AUP74_RS05295 c9c9ed2301da4871b85a58949f535ac7 733 SUPERFAMILY SSF82784 1 126 6.81E-20 T 11-11-2016 IPR003718 OsmC/Ohr family AUP74_RS05295 c9c9ed2301da4871b85a58949f535ac7 733 Pfam PF02566 OsmC-like protein 32 127 1.1E-10 T 11-11-2016 IPR003718 OsmC/Ohr family AUP74_RS05295 c9c9ed2301da4871b85a58949f535ac7 733 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 205 540 6.0E-73 T 11-11-2016 IPR003776 YcaO-like domain AUP74_RS05295 c9c9ed2301da4871b85a58949f535ac7 733 TIGRFAM TIGR00702 TIGR00702: YcaO-type kinase domain 159 551 1.1E-99 T 11-11-2016 IPR003776 YcaO-like domain AUP74_RS05295 c9c9ed2301da4871b85a58949f535ac7 733 Gene3D G3DSA:3.30.300.20 1 129 8.7E-32 T 11-11-2016 IPR015946 K homology domain-like, alpha/beta AUP74_RS05295 c9c9ed2301da4871b85a58949f535ac7 733 TIGRFAM TIGR03549 TIGR03549: YcaO domain protein 2 727 0.0 T 11-11-2016 IPR019938 YcaO domain protein AUP74_RS16860 5242ff3586b964a49146017a0dde08e7 199 Gene3D G3DSA:2.102.10.10 6 197 2.5E-40 T 11-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AUP74_RS16860 5242ff3586b964a49146017a0dde08e7 199 SUPERFAMILY SSF50022 30 195 3.98E-40 T 11-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AUP74_RS16860 5242ff3586b964a49146017a0dde08e7 199 Pfam PF00355 Rieske [2Fe-2S] domain 54 178 2.8E-12 T 11-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AUP74_RS16860 5242ff3586b964a49146017a0dde08e7 199 Pfam PF10399 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal 2 40 6.3E-16 T 11-11-2016 IPR019470 Ubiquitinol-cytochrome C reductase, Fe-S subunit, TAT signal GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 AUP74_RS16860 5242ff3586b964a49146017a0dde08e7 199 TIGRFAM TIGR01416 Rieske_proteo: ubiquinol-cytochrome c reductase, iron-sulfur subunit 9 192 3.4E-71 T 11-11-2016 IPR006317 Ubiquinol-cytochrome c reductase, iron-sulphur subunit GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 AUP74_RS16860 5242ff3586b964a49146017a0dde08e7 199 PRINTS PR00162 Rieske 2Fe-2S subunit signature 119 130 6.4E-7 T 11-11-2016 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 AUP74_RS16860 5242ff3586b964a49146017a0dde08e7 199 PRINTS PR00162 Rieske 2Fe-2S subunit signature 151 163 6.4E-7 T 11-11-2016 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 AUP74_RS06300 9880123d40007acf065c7b44b00394f3 343 Gene3D G3DSA:2.40.128.130 35 343 7.2E-30 T 11-11-2016 IPR005546 Autotransporter beta-domain AUP74_RS06300 9880123d40007acf065c7b44b00394f3 343 SMART SM00869 74 330 3.5E-4 T 11-11-2016 IPR005546 Autotransporter beta-domain AUP74_RS06300 9880123d40007acf065c7b44b00394f3 343 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 34 343 8.0E-16 T 11-11-2016 IPR006315 Outer membrane autotransporter barrel GO:0019867 AUP74_RS06300 9880123d40007acf065c7b44b00394f3 343 SUPERFAMILY SSF103515 47 343 2.35E-13 T 11-11-2016 IPR005546 Autotransporter beta-domain AUP74_RS01515 a72a0e6a1eaf0abb0a7e00b1dfd370d9 1121 Gene3D G3DSA:2.60.40.10 364 464 2.0E-16 T 11-11-2016 IPR013783 Immunoglobulin-like fold AUP74_RS01515 a72a0e6a1eaf0abb0a7e00b1dfd370d9 1121 Pfam PF00128 Alpha amylase, catalytic domain 613 658 1.6E-4 T 11-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AUP74_RS01515 a72a0e6a1eaf0abb0a7e00b1dfd370d9 1121 Pfam PF11852 Domain of unknown function (DUF3372) 947 1108 1.2E-52 T 11-11-2016 IPR024561 Alpha-1,6-glucosidases, pullulanase-type, C-terminal AUP74_RS01515 a72a0e6a1eaf0abb0a7e00b1dfd370d9 1121 SUPERFAMILY SSF81296 235 356 2.8E-26 T 11-11-2016 IPR014756 Immunoglobulin E-set AUP74_RS01515 a72a0e6a1eaf0abb0a7e00b1dfd370d9 1121 SUPERFAMILY SSF81296 357 470 3.8E-21 T 11-11-2016 IPR014756 Immunoglobulin E-set AUP74_RS01515 a72a0e6a1eaf0abb0a7e00b1dfd370d9 1121 SUPERFAMILY SSF51445 462 1005 3.15E-130 T 11-11-2016 IPR017853 Glycoside hydrolase superfamily AUP74_RS01515 a72a0e6a1eaf0abb0a7e00b1dfd370d9 1121 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 364 450 8.9E-14 T 11-11-2016 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 AUP74_RS01515 a72a0e6a1eaf0abb0a7e00b1dfd370d9 1121 TIGRFAM TIGR02103 pullul_strch: alpha-1,6-glucosidases, pullulanase-type 239 1109 0.0 T 11-11-2016 IPR011839 Alpha-1,6-glucosidases, pullulanase-type GO:0005975|GO:0051060 AUP74_RS01515 a72a0e6a1eaf0abb0a7e00b1dfd370d9 1121 SMART SM00642 584 966 0.0083 T 11-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AUP74_RS01515 a72a0e6a1eaf0abb0a7e00b1dfd370d9 1121 SUPERFAMILY SSF51011 1011 1112 1.98E-24 T 11-11-2016 AUP74_RS01515 a72a0e6a1eaf0abb0a7e00b1dfd370d9 1121 Gene3D G3DSA:3.20.20.80 479 945 2.6E-88 T 11-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 AUP74_RS01515 a72a0e6a1eaf0abb0a7e00b1dfd370d9 1121 Gene3D G3DSA:3.20.20.80 980 1006 2.6E-88 T 11-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 AUP74_RS07995 af55cfa8cb0233858c4989134a45c525 348 Pfam PF13437 HlyD family secretion protein 209 288 5.3E-6 T 11-11-2016 AUP74_RS07995 af55cfa8cb0233858c4989134a45c525 348 Gene3D G3DSA:2.40.50.100 49 78 4.6E-8 T 11-11-2016 AUP74_RS07995 af55cfa8cb0233858c4989134a45c525 348 Gene3D G3DSA:2.40.50.100 202 238 4.6E-8 T 11-11-2016 AUP74_RS07995 af55cfa8cb0233858c4989134a45c525 348 Pfam PF13533 Biotin-lipoyl like 52 83 1.2E-6 T 11-11-2016 AUP74_RS07995 af55cfa8cb0233858c4989134a45c525 348 SUPERFAMILY SSF111369 116 170 1.02E-5 T 11-11-2016 AUP74_RS12855 e05379b513f24a5a1e3b0fbff088f8e2 192 ProDom PD037115 UPF0274 YCFC HI0638 METABOLISM UNCHARACTERIZED VV1342 PURINE INVOLVED SO2634 HFLD 1 183 3.0E-40 T 11-11-2016 IPR007451 Uncharacterised protein family UPF0274 AUP74_RS12855 e05379b513f24a5a1e3b0fbff088f8e2 192 SUPERFAMILY SSF101322 2 187 1.44E-56 T 11-11-2016 IPR007451 Uncharacterised protein family UPF0274 AUP74_RS12855 e05379b513f24a5a1e3b0fbff088f8e2 192 Pfam PF04356 Protein of unknown function (DUF489) 1 177 2.4E-60 T 11-11-2016 IPR007451 Uncharacterised protein family UPF0274 AUP74_RS12855 e05379b513f24a5a1e3b0fbff088f8e2 192 Hamap MF_00695 High frequency lysogenization protein HflD [hflD]. 1 185 26.738 T 11-11-2016 IPR007451 Uncharacterised protein family UPF0274 AUP74_RS12855 e05379b513f24a5a1e3b0fbff088f8e2 192 Gene3D G3DSA:1.10.3890.10 1 187 2.5E-64 T 11-11-2016 IPR007451 Uncharacterised protein family UPF0274 AUP74_RS02250 a4679caf0771d1b6e7dad74e42d81c29 950 SUPERFAMILY SSF81301 47 291 2.4E-80 T 11-11-2016 AUP74_RS02250 a4679caf0771d1b6e7dad74e42d81c29 950 SUPERFAMILY SSF81301 534 818 9.48E-86 T 11-11-2016 AUP74_RS02250 a4679caf0771d1b6e7dad74e42d81c29 950 Hamap MF_00802 Glutamate-ammonia-ligase adenylyltransferase [glnE]. 42 950 19.152 T 11-11-2016 IPR023057 Glutamate-ammonia-ligase adenylyltransferase GO:0008882 AUP74_RS02250 a4679caf0771d1b6e7dad74e42d81c29 950 SUPERFAMILY SSF81593 292 438 2.67E-41 T 11-11-2016 AUP74_RS02250 a4679caf0771d1b6e7dad74e42d81c29 950 Pfam PF08335 GlnD PII-uridylyltransferase 302 440 3.9E-37 T 11-11-2016 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 AUP74_RS02250 a4679caf0771d1b6e7dad74e42d81c29 950 Pfam PF08335 GlnD PII-uridylyltransferase 832 922 5.4E-13 T 11-11-2016 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 AUP74_RS02250 a4679caf0771d1b6e7dad74e42d81c29 950 SUPERFAMILY SSF81593 821 950 5.1E-31 T 11-11-2016 AUP74_RS02250 a4679caf0771d1b6e7dad74e42d81c29 950 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 560 811 3.3E-88 T 11-11-2016 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 AUP74_RS02250 a4679caf0771d1b6e7dad74e42d81c29 950 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 53 280 5.8E-77 T 11-11-2016 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 AUP74_RS02250 a4679caf0771d1b6e7dad74e42d81c29 950 Gene3D G3DSA:3.30.460.10 646 816 2.9E-61 T 11-11-2016 AUP74_RS02250 a4679caf0771d1b6e7dad74e42d81c29 950 Gene3D G3DSA:3.30.460.10 120 290 1.2E-64 T 11-11-2016 AUP74_RS08075 fa8405c09033b3529616416c14f81530 280 Pfam PF00809 Pterin binding enzyme 18 262 2.4E-83 T 11-11-2016 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AUP74_RS08075 fa8405c09033b3529616416c14f81530 280 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 17 32 - T 11-11-2016 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AUP74_RS08075 fa8405c09033b3529616416c14f81530 280 Gene3D G3DSA:3.20.20.20 12 277 4.3E-104 T 11-11-2016 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AUP74_RS08075 fa8405c09033b3529616416c14f81530 280 SUPERFAMILY SSF51717 3 276 4.19E-100 T 11-11-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AUP74_RS08075 fa8405c09033b3529616416c14f81530 280 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 56 69 - T 11-11-2016 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AUP74_RS08075 fa8405c09033b3529616416c14f81530 280 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 16 274 6.5E-97 T 11-11-2016 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 AUP74_RS16650 4699e346afd57bb3ff11aeb0de9e565b 173 Gene3D G3DSA:3.30.700.10 7 173 3.7E-38 T 11-11-2016 AUP74_RS16650 4699e346afd57bb3ff11aeb0de9e565b 173 Pfam PF13633 Prokaryotic N-terminal methylation site 5 30 1.8E-11 T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS16650 4699e346afd57bb3ff11aeb0de9e565b 173 Pfam PF00114 Pilin (bacterial filament) 35 173 1.9E-12 T 11-11-2016 IPR001082 Fimbrial protein pilin GO:0007155|GO:0009289 AUP74_RS16650 4699e346afd57bb3ff11aeb0de9e565b 173 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 5 25 - T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS16650 4699e346afd57bb3ff11aeb0de9e565b 173 SUPERFAMILY SSF54523 7 126 4.03E-20 T 11-11-2016 AUP74_RS16650 4699e346afd57bb3ff11aeb0de9e565b 173 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 27 5.1E-9 T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS15675 c3ea27449dd9fa989c7e2d000c6a8bbd 224 SUPERFAMILY SSF48150 7 218 1.19E-66 T 11-11-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AUP74_RS15675 c3ea27449dd9fa989c7e2d000c6a8bbd 224 PIRSF PIRSF001435 6 220 1.7E-48 T 11-11-2016 IPR005759 Endonuclease III GO:0003906|GO:0006284 AUP74_RS15675 c3ea27449dd9fa989c7e2d000c6a8bbd 224 ProSitePatterns PS01155 Endonuclease III family signature. 110 139 - T 11-11-2016 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 AUP74_RS15675 c3ea27449dd9fa989c7e2d000c6a8bbd 224 Gene3D G3DSA:1.10.1670.10 131 214 2.7E-30 T 11-11-2016 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 AUP74_RS15675 c3ea27449dd9fa989c7e2d000c6a8bbd 224 TIGRFAM TIGR01083 nth: endonuclease III 12 198 4.0E-69 T 11-11-2016 IPR005759 Endonuclease III GO:0003906|GO:0006284 AUP74_RS15675 c3ea27449dd9fa989c7e2d000c6a8bbd 224 Hamap MF_00942 Endonuclease III [nth]. 8 217 34.891 T 11-11-2016 IPR005759 Endonuclease III GO:0003906|GO:0006284 AUP74_RS15675 c3ea27449dd9fa989c7e2d000c6a8bbd 224 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 42 176 2.1E-21 T 11-11-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AUP74_RS15675 c3ea27449dd9fa989c7e2d000c6a8bbd 224 SMART SM00478 46 193 1.9E-56 T 11-11-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AUP74_RS15675 c3ea27449dd9fa989c7e2d000c6a8bbd 224 Gene3D G3DSA:1.10.340.30 33 130 1.5E-31 T 11-11-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AUP74_RS13325 5cbec480250bb2d4118c9f2ebeccd9bb 158 SUPERFAMILY SSF46785 4 63 1.25E-15 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS13325 5cbec480250bb2d4118c9f2ebeccd9bb 158 Gene3D G3DSA:1.10.10.10 1 54 7.8E-23 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS13325 5cbec480250bb2d4118c9f2ebeccd9bb 158 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 51 1.4E-17 T 11-11-2016 AUP74_RS13325 5cbec480250bb2d4118c9f2ebeccd9bb 158 Pfam PF01037 Lrp/AsnC ligand binding domain 71 143 6.1E-23 T 11-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AUP74_RS13325 5cbec480250bb2d4118c9f2ebeccd9bb 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 2.0E-14 T 11-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 AUP74_RS13325 5cbec480250bb2d4118c9f2ebeccd9bb 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 2.0E-14 T 11-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 AUP74_RS13325 5cbec480250bb2d4118c9f2ebeccd9bb 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 2.0E-14 T 11-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 AUP74_RS13325 5cbec480250bb2d4118c9f2ebeccd9bb 158 SUPERFAMILY SSF54909 64 152 4.83E-23 T 11-11-2016 IPR011008 Dimeric alpha-beta barrel AUP74_RS13325 5cbec480250bb2d4118c9f2ebeccd9bb 158 Gene3D G3DSA:3.30.70.920 57 140 1.9E-31 T 11-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AUP74_RS13325 5cbec480250bb2d4118c9f2ebeccd9bb 158 ProSitePatterns PS00519 AsnC-type HTH domain signature. 22 48 - T 11-11-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site AUP74_RS13325 5cbec480250bb2d4118c9f2ebeccd9bb 158 SMART SM00344 4 113 2.8E-45 T 11-11-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AUP74_RS14865 ffd51b9c130c6f4da7b8efc0193fc64b 378 SUPERFAMILY SSF88659 229 298 1.66E-5 T 11-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS14865 ffd51b9c130c6f4da7b8efc0193fc64b 378 Pfam PF04542 Sigma-70 region 2 155 223 2.8E-18 T 11-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS14865 ffd51b9c130c6f4da7b8efc0193fc64b 378 SUPERFAMILY SSF88659 285 377 4.3E-22 T 11-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS14865 ffd51b9c130c6f4da7b8efc0193fc64b 378 PRINTS PR00046 Major sigma-70 factor signature 362 373 1.3E-19 T 11-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS14865 ffd51b9c130c6f4da7b8efc0193fc64b 378 PRINTS PR00046 Major sigma-70 factor signature 203 211 1.3E-19 T 11-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS14865 ffd51b9c130c6f4da7b8efc0193fc64b 378 PRINTS PR00046 Major sigma-70 factor signature 179 192 1.3E-19 T 11-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS14865 ffd51b9c130c6f4da7b8efc0193fc64b 378 PRINTS PR00046 Major sigma-70 factor signature 347 362 1.3E-19 T 11-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS14865 ffd51b9c130c6f4da7b8efc0193fc64b 378 PRINTS PR00046 Major sigma-70 factor signature 326 338 1.3E-19 T 11-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS14865 ffd51b9c130c6f4da7b8efc0193fc64b 378 Gene3D G3DSA:1.10.10.10 317 377 3.7E-16 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS14865 ffd51b9c130c6f4da7b8efc0193fc64b 378 Pfam PF04545 Sigma-70, region 4 323 375 1.2E-14 T 11-11-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS14865 ffd51b9c130c6f4da7b8efc0193fc64b 378 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 179 192 - T 11-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS14865 ffd51b9c130c6f4da7b8efc0193fc64b 378 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 151 376 1.9E-36 T 11-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS14865 ffd51b9c130c6f4da7b8efc0193fc64b 378 SUPERFAMILY SSF88946 52 77 4.55E-38 T 11-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS14865 ffd51b9c130c6f4da7b8efc0193fc64b 378 SUPERFAMILY SSF88946 139 219 4.55E-38 T 11-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS14865 ffd51b9c130c6f4da7b8efc0193fc64b 378 Gene3D G3DSA:1.10.601.10 147 221 8.7E-41 T 11-11-2016 AUP74_RS14865 ffd51b9c130c6f4da7b8efc0193fc64b 378 Gene3D G3DSA:1.10.601.10 21 85 8.7E-41 T 11-11-2016 AUP74_RS06090 0ea306e6a0e05cecedd622200a3455ba 376 Gene3D G3DSA:3.40.50.1000 220 352 4.6E-35 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS06090 0ea306e6a0e05cecedd622200a3455ba 376 Gene3D G3DSA:1.10.150.210 168 219 5.9E-24 T 11-11-2016 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 AUP74_RS06090 0ea306e6a0e05cecedd622200a3455ba 376 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 159 329 5.5E-32 T 11-11-2016 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 AUP74_RS06090 0ea306e6a0e05cecedd622200a3455ba 376 Pfam PF12710 haloacid dehalogenase-like hydrolase 159 327 9.9E-22 T 11-11-2016 AUP74_RS06090 0ea306e6a0e05cecedd622200a3455ba 376 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 156 357 3.5E-65 T 11-11-2016 AUP74_RS06090 0ea306e6a0e05cecedd622200a3455ba 376 SUPERFAMILY SSF56784 158 363 4.4E-44 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS11355 5d1ef540dda49bf1780d83bc39bf7b44 529 Gene3D G3DSA:3.50.50.60 211 326 3.3E-24 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS11355 5d1ef540dda49bf1780d83bc39bf7b44 529 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 264 274 1.1E-63 T 11-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AUP74_RS11355 5d1ef540dda49bf1780d83bc39bf7b44 529 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 438 459 1.1E-63 T 11-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AUP74_RS11355 5d1ef540dda49bf1780d83bc39bf7b44 529 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 473 491 1.1E-63 T 11-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AUP74_RS11355 5d1ef540dda49bf1780d83bc39bf7b44 529 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 212 234 1.1E-63 T 11-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AUP74_RS11355 5d1ef540dda49bf1780d83bc39bf7b44 529 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 399 415 1.1E-63 T 11-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AUP74_RS11355 5d1ef540dda49bf1780d83bc39bf7b44 529 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 310 318 1.1E-63 T 11-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AUP74_RS11355 5d1ef540dda49bf1780d83bc39bf7b44 529 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 347 371 1.1E-63 T 11-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AUP74_RS11355 5d1ef540dda49bf1780d83bc39bf7b44 529 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 244 259 1.1E-63 T 11-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AUP74_RS11355 5d1ef540dda49bf1780d83bc39bf7b44 529 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 332 344 1.1E-63 T 11-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AUP74_RS11355 5d1ef540dda49bf1780d83bc39bf7b44 529 Gene3D G3DSA:3.50.50.60 436 513 7.7E-14 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS11355 5d1ef540dda49bf1780d83bc39bf7b44 529 SUPERFAMILY SSF51905 205 509 1.69E-54 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS11355 5d1ef540dda49bf1780d83bc39bf7b44 529 SUPERFAMILY SSF52833 1 99 6.26E-26 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS11355 5d1ef540dda49bf1780d83bc39bf7b44 529 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 211 488 2.4E-47 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS11355 5d1ef540dda49bf1780d83bc39bf7b44 529 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 463 485 1.9E-39 T 11-11-2016 AUP74_RS11355 5d1ef540dda49bf1780d83bc39bf7b44 529 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 436 452 1.9E-39 T 11-11-2016 AUP74_RS11355 5d1ef540dda49bf1780d83bc39bf7b44 529 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 213 232 1.9E-39 T 11-11-2016 AUP74_RS11355 5d1ef540dda49bf1780d83bc39bf7b44 529 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 351 369 1.9E-39 T 11-11-2016 AUP74_RS11355 5d1ef540dda49bf1780d83bc39bf7b44 529 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 309 327 1.9E-39 T 11-11-2016 AUP74_RS11355 5d1ef540dda49bf1780d83bc39bf7b44 529 Gene3D G3DSA:3.50.50.60 327 435 2.1E-32 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS11355 5d1ef540dda49bf1780d83bc39bf7b44 529 SUPERFAMILY SSF52833 103 195 6.8E-23 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS11355 5d1ef540dda49bf1780d83bc39bf7b44 529 Gene3D G3DSA:3.40.30.10 1 92 5.3E-29 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS11355 5d1ef540dda49bf1780d83bc39bf7b44 529 Pfam PF13192 Thioredoxin domain 123 193 1.1E-9 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS11355 5d1ef540dda49bf1780d83bc39bf7b44 529 PIRSF PIRSF000238 1 516 7.7E-259 T 11-11-2016 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 AUP74_RS11355 5d1ef540dda49bf1780d83bc39bf7b44 529 Gene3D G3DSA:3.40.30.10 102 194 1.5E-37 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS11355 5d1ef540dda49bf1780d83bc39bf7b44 529 TIGRFAM TIGR03140 AhpF: alkyl hydroperoxide reductase subunit F 1 513 1.7E-245 T 11-11-2016 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 AUP74_RS11355 5d1ef540dda49bf1780d83bc39bf7b44 529 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 339 359 - T 11-11-2016 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 AUP74_RS12140 8470ed7a5e3d145e96639001ca0d4845 231 SUPERFAMILY SSF46894 146 222 9.52E-23 T 11-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AUP74_RS12140 8470ed7a5e3d145e96639001ca0d4845 231 SMART SM00448 3 123 1.2E-35 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS12140 8470ed7a5e3d145e96639001ca0d4845 231 Gene3D G3DSA:3.40.50.2300 2 130 1.7E-40 T 11-11-2016 AUP74_RS12140 8470ed7a5e3d145e96639001ca0d4845 231 SMART SM00421 159 216 7.6E-27 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS12140 8470ed7a5e3d145e96639001ca0d4845 231 Pfam PF00072 Response regulator receiver domain 5 124 1.5E-28 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS12140 8470ed7a5e3d145e96639001ca0d4845 231 SUPERFAMILY SSF52172 2 142 1.14E-35 T 11-11-2016 IPR011006 CheY-like superfamily AUP74_RS12140 8470ed7a5e3d145e96639001ca0d4845 231 Gene3D G3DSA:1.10.10.10 131 222 1.1E-33 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS12140 8470ed7a5e3d145e96639001ca0d4845 231 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 192 204 4.7E-14 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS12140 8470ed7a5e3d145e96639001ca0d4845 231 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 176 4.7E-14 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS12140 8470ed7a5e3d145e96639001ca0d4845 231 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 192 4.7E-14 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS12140 8470ed7a5e3d145e96639001ca0d4845 231 Pfam PF00196 Bacterial regulatory proteins, luxR family 161 216 1.9E-20 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS12140 8470ed7a5e3d145e96639001ca0d4845 231 ProSitePatterns PS00622 LuxR-type HTH domain signature. 176 203 - T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS09775 205a4540dca11e5c743e85a97257c4d4 381 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 371 2.0E-159 T 11-11-2016 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 AUP74_RS09775 205a4540dca11e5c743e85a97257c4d4 381 Gene3D G3DSA:3.40.50.1770 196 359 3.6E-31 T 11-11-2016 AUP74_RS09775 205a4540dca11e5c743e85a97257c4d4 381 PIRSF PIRSF000183 1 371 1.9E-157 T 11-11-2016 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 AUP74_RS09775 205a4540dca11e5c743e85a97257c4d4 381 SMART SM01003 4 137 1.3E-78 T 11-11-2016 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal AUP74_RS09775 205a4540dca11e5c743e85a97257c4d4 381 SUPERFAMILY SSF51735 137 303 1.73E-51 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS09775 205a4540dca11e5c743e85a97257c4d4 381 SUPERFAMILY SSF52283 305 360 3.83E-67 T 11-11-2016 AUP74_RS09775 205a4540dca11e5c743e85a97257c4d4 381 SUPERFAMILY SSF52283 1 137 3.83E-67 T 11-11-2016 AUP74_RS09775 205a4540dca11e5c743e85a97257c4d4 381 Gene3D G3DSA:3.40.50.1770 1 176 9.4E-61 T 11-11-2016 AUP74_RS09775 205a4540dca11e5c743e85a97257c4d4 381 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 173 198 - T 11-11-2016 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 AUP74_RS09775 205a4540dca11e5c743e85a97257c4d4 381 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 1.5E-46 T 11-11-2016 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal AUP74_RS09775 205a4540dca11e5c743e85a97257c4d4 381 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 352 7.2E-83 T 11-11-2016 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain AUP74_RS09775 205a4540dca11e5c743e85a97257c4d4 381 Gene3D G3DSA:3.40.50.720 177 195 1.2E-6 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS09775 205a4540dca11e5c743e85a97257c4d4 381 SMART SM01002 149 297 3.5E-91 T 11-11-2016 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain AUP74_RS15050 699745de5280f2276bb26c3e10a47638 490 PRINTS PR00934 X-His dipeptidase (M25) signature 159 177 1.6E-71 T 11-11-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 AUP74_RS15050 699745de5280f2276bb26c3e10a47638 490 PRINTS PR00934 X-His dipeptidase (M25) signature 206 223 1.6E-71 T 11-11-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 AUP74_RS15050 699745de5280f2276bb26c3e10a47638 490 PRINTS PR00934 X-His dipeptidase (M25) signature 252 271 1.6E-71 T 11-11-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 AUP74_RS15050 699745de5280f2276bb26c3e10a47638 490 PRINTS PR00934 X-His dipeptidase (M25) signature 367 385 1.6E-71 T 11-11-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 AUP74_RS15050 699745de5280f2276bb26c3e10a47638 490 PRINTS PR00934 X-His dipeptidase (M25) signature 101 119 1.6E-71 T 11-11-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 AUP74_RS15050 699745de5280f2276bb26c3e10a47638 490 PRINTS PR00934 X-His dipeptidase (M25) signature 135 152 1.6E-71 T 11-11-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 AUP74_RS15050 699745de5280f2276bb26c3e10a47638 490 PRINTS PR00934 X-His dipeptidase (M25) signature 80 99 1.6E-71 T 11-11-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 AUP74_RS15050 699745de5280f2276bb26c3e10a47638 490 PRINTS PR00934 X-His dipeptidase (M25) signature 454 476 1.6E-71 T 11-11-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 AUP74_RS15050 699745de5280f2276bb26c3e10a47638 490 PRINTS PR00934 X-His dipeptidase (M25) signature 432 448 1.6E-71 T 11-11-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 AUP74_RS15050 699745de5280f2276bb26c3e10a47638 490 Pfam PF01546 Peptidase family M20/M25/M40 73 484 6.0E-19 T 11-11-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 AUP74_RS15050 699745de5280f2276bb26c3e10a47638 490 SUPERFAMILY SSF53187 401 486 2.77E-65 T 11-11-2016 AUP74_RS15050 699745de5280f2276bb26c3e10a47638 490 SUPERFAMILY SSF53187 11 182 2.77E-65 T 11-11-2016 AUP74_RS15050 699745de5280f2276bb26c3e10a47638 490 Gene3D G3DSA:3.40.630.10 2 181 1.6E-104 T 11-11-2016 AUP74_RS15050 699745de5280f2276bb26c3e10a47638 490 Gene3D G3DSA:3.40.630.10 401 487 1.6E-104 T 11-11-2016 AUP74_RS15050 699745de5280f2276bb26c3e10a47638 490 TIGRFAM TIGR01893 aa-his-dipept: Xaa-His dipeptidase 8 486 6.0E-167 T 11-11-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 AUP74_RS15050 699745de5280f2276bb26c3e10a47638 490 PIRSF PIRSF016599 1 489 2.2E-185 T 11-11-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 AUP74_RS00690 8d2fc4d038cf04a86975820405e415c4 234 Pfam PF13661 2OG-Fe(II) oxygenase superfamily 137 229 4.8E-25 T 11-11-2016 AUP74_RS00690 8d2fc4d038cf04a86975820405e415c4 234 SMART SM00702 21 229 7.8E-4 T 11-11-2016 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 AUP74_RS01615 d42c6c6b7dcf37c72230caf59476e91c 455 SUPERFAMILY SSF102114 10 442 1.28E-125 T 11-11-2016 AUP74_RS01615 d42c6c6b7dcf37c72230caf59476e91c 455 Pfam PF04055 Radical SAM superfamily 54 225 1.5E-19 T 11-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 AUP74_RS01615 d42c6c6b7dcf37c72230caf59476e91c 455 Pfam PF06969 HemN C-terminal domain 361 428 3.8E-13 T 11-11-2016 IPR010723 HemN, C-terminal AUP74_RS01615 d42c6c6b7dcf37c72230caf59476e91c 455 TIGRFAM TIGR00538 hemN: oxygen-independent coproporphyrinogen III oxidase 10 455 2.0E-145 T 11-11-2016 IPR004558 Coproporphyrinogen III oxidase, oxygen-independent, HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.99.22 AUP74_RS01615 d42c6c6b7dcf37c72230caf59476e91c 455 PIRSF PIRSF000167 5 453 2.0E-150 T 11-11-2016 IPR004558 Coproporphyrinogen III oxidase, oxygen-independent, HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.99.22 AUP74_RS01615 d42c6c6b7dcf37c72230caf59476e91c 455 Gene3D G3DSA:3.80.30.20 51 246 2.9E-29 T 11-11-2016 IPR023404 Radical SAM, alpha/beta horseshoe AUP74_RS01615 d42c6c6b7dcf37c72230caf59476e91c 455 SMART SM00729 49 267 2.5E-44 T 11-11-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 AUP74_RS01980 07a4bde1b88658eb16e8df84750fafd4 620 Gene3D G3DSA:2.60.40.10 25 113 1.1E-28 T 11-11-2016 IPR013783 Immunoglobulin-like fold AUP74_RS01980 07a4bde1b88658eb16e8df84750fafd4 620 Pfam PF00128 Alpha amylase, catalytic domain 167 484 6.5E-48 T 11-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AUP74_RS01980 07a4bde1b88658eb16e8df84750fafd4 620 SMART SM00642 133 533 1.0E-59 T 11-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AUP74_RS01980 07a4bde1b88658eb16e8df84750fafd4 620 Pfam PF09087 Cyclomaltodextrinase, N-terminal 29 115 4.2E-28 T 11-11-2016 IPR015171 Cyclomaltodextrinase, N-terminal AUP74_RS01980 07a4bde1b88658eb16e8df84750fafd4 620 SUPERFAMILY SSF51445 129 542 8.22E-99 T 11-11-2016 IPR017853 Glycoside hydrolase superfamily AUP74_RS01980 07a4bde1b88658eb16e8df84750fafd4 620 SUPERFAMILY SSF81296 27 116 4.34E-25 T 11-11-2016 IPR014756 Immunoglobulin E-set AUP74_RS01980 07a4bde1b88658eb16e8df84750fafd4 620 Pfam PF10438 Cyclo-malto-dextrinase C-terminal domain 544 618 1.5E-24 T 11-11-2016 IPR019492 Cyclo-malto-dextrinase, C-terminal AUP74_RS01980 07a4bde1b88658eb16e8df84750fafd4 620 Gene3D G3DSA:3.20.20.80 130 541 3.5E-100 T 11-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 AUP74_RS01980 07a4bde1b88658eb16e8df84750fafd4 620 SUPERFAMILY SSF51011 543 619 2.21E-14 T 11-11-2016 AUP74_RS01980 07a4bde1b88658eb16e8df84750fafd4 620 Gene3D G3DSA:2.60.40.1180 543 619 4.6E-25 T 11-11-2016 IPR013780 Glycosyl hydrolase, all-beta AUP74_RS00940 1883108346d8b3b29b41e90ac1890826 202 Pfam PF01330 RuvA N terminal domain 1 62 2.3E-20 T 11-11-2016 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 AUP74_RS00940 1883108346d8b3b29b41e90ac1890826 202 Pfam PF14520 Helix-hairpin-helix domain 72 130 2.6E-17 T 11-11-2016 AUP74_RS00940 1883108346d8b3b29b41e90ac1890826 202 SMART SM00278 73 92 0.24 T 11-11-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AUP74_RS00940 1883108346d8b3b29b41e90ac1890826 202 SMART SM00278 108 127 0.067 T 11-11-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AUP74_RS00940 1883108346d8b3b29b41e90ac1890826 202 Gene3D G3DSA:1.10.150.20 67 132 6.7E-29 T 11-11-2016 AUP74_RS00940 1883108346d8b3b29b41e90ac1890826 202 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 197 1.2E-53 T 11-11-2016 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 AUP74_RS00940 1883108346d8b3b29b41e90ac1890826 202 Pfam PF07499 RuvA, C-terminal domain 154 199 6.4E-14 T 11-11-2016 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 AUP74_RS00940 1883108346d8b3b29b41e90ac1890826 202 Gene3D G3DSA:1.10.8.10 154 199 1.7E-17 T 11-11-2016 AUP74_RS00940 1883108346d8b3b29b41e90ac1890826 202 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 200 30.33 T 11-11-2016 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 AUP74_RS00940 1883108346d8b3b29b41e90ac1890826 202 SUPERFAMILY SSF46929 155 199 2.35E-10 T 11-11-2016 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 AUP74_RS00940 1883108346d8b3b29b41e90ac1890826 202 Gene3D G3DSA:2.40.50.140 1 65 2.8E-25 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS00940 1883108346d8b3b29b41e90ac1890826 202 SUPERFAMILY SSF47781 66 133 1.72E-21 T 11-11-2016 IPR010994 RuvA domain 2-like AUP74_RS00940 1883108346d8b3b29b41e90ac1890826 202 SUPERFAMILY SSF50249 1 63 8.0E-17 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS05240 672102cd7b6ea66d92d4778375e10806 624 Gene3D G3DSA:3.40.50.300 397 452 1.9E-9 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05240 672102cd7b6ea66d92d4778375e10806 624 SUPERFAMILY SSF52540 346 455 7.16E-47 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05240 672102cd7b6ea66d92d4778375e10806 624 SUPERFAMILY SSF52540 11 288 7.16E-47 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05240 672102cd7b6ea66d92d4778375e10806 624 Gene3D G3DSA:3.40.50.300 11 227 4.7E-34 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05240 672102cd7b6ea66d92d4778375e10806 624 Pfam PF13538 UvrD-like helicase C-terminal domain 402 452 1.6E-8 T 11-11-2016 IPR027785 UvrD-like helicase C-terminal domain AUP74_RS05240 672102cd7b6ea66d92d4778375e10806 624 Pfam PF00580 UvrD/REP helicase N-terminal domain 116 190 3.7E-8 T 11-11-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 AUP74_RS05240 672102cd7b6ea66d92d4778375e10806 624 Pfam PF00580 UvrD/REP helicase N-terminal domain 13 85 2.1E-13 T 11-11-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 AUP74_RS10865 107600fb438d99f05657496f5c0ad2c9 583 SUPERFAMILY SSF81606 184 384 7.32E-8 T 11-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 AUP74_RS10865 107600fb438d99f05657496f5c0ad2c9 583 SMART SM00331 170 384 6.2E-20 T 11-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 AUP74_RS10865 107600fb438d99f05657496f5c0ad2c9 583 Gene3D G3DSA:3.40.50.2300 1 125 1.6E-5 T 11-11-2016 AUP74_RS10865 107600fb438d99f05657496f5c0ad2c9 583 SUPERFAMILY SSF52172 1 142 8.56E-7 T 11-11-2016 IPR011006 CheY-like superfamily AUP74_RS10865 107600fb438d99f05657496f5c0ad2c9 583 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 196 384 1.6E-34 T 11-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 AUP74_RS10865 107600fb438d99f05657496f5c0ad2c9 583 SUPERFAMILY SSF55874 434 464 1.29E-5 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS10865 107600fb438d99f05657496f5c0ad2c9 583 SUPERFAMILY SSF55874 493 551 1.29E-5 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS06770 6515f034613674b434a6c35bfc96b370 232 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 43.254 T 11-11-2016 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 AUP74_RS06770 6515f034613674b434a6c35bfc96b370 232 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 228 2.9E-104 T 11-11-2016 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 AUP74_RS06770 6515f034613674b434a6c35bfc96b370 232 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 11-11-2016 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06770 6515f034613674b434a6c35bfc96b370 232 SUPERFAMILY SSF56808 6 225 9.81E-81 T 11-11-2016 IPR023674 Ribosomal protein L1-like AUP74_RS06770 6515f034613674b434a6c35bfc96b370 232 PIRSF PIRSF002155 1 227 2.7E-78 T 11-11-2016 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06770 6515f034613674b434a6c35bfc96b370 232 Gene3D G3DSA:3.40.50.790 69 159 3.9E-41 T 11-11-2016 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich AUP74_RS06770 6515f034613674b434a6c35bfc96b370 232 Pfam PF00687 Ribosomal protein L1p/L10e family 30 220 1.8E-51 T 11-11-2016 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein AUP74_RS06770 6515f034613674b434a6c35bfc96b370 232 Gene3D G3DSA:3.30.190.20 161 225 2.2E-45 T 11-11-2016 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 AUP74_RS06770 6515f034613674b434a6c35bfc96b370 232 Gene3D G3DSA:3.30.190.20 18 68 2.2E-45 T 11-11-2016 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 AUP74_RS09825 a91b4442ad23d0de1ee64d312a011be6 365 Pfam PF09839 Uncharacterized protein conserved in bacteria (DUF2066) 27 259 7.0E-60 T 11-11-2016 IPR018642 Protein of unknown function DUF2066 AUP74_RS07350 9940030657c54b50028ae5f16fcd0d66 527 Gene3D G3DSA:2.40.30.10 290 392 1.3E-24 T 11-11-2016 AUP74_RS07350 9940030657c54b50028ae5f16fcd0d66 527 SUPERFAMILY SSF54980 391 466 1.47E-18 T 11-11-2016 IPR009022 Elongation factor G, III-V domain AUP74_RS07350 9940030657c54b50028ae5f16fcd0d66 527 Gene3D G3DSA:3.40.50.300 14 279 4.8E-64 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS07350 9940030657c54b50028ae5f16fcd0d66 527 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 57 72 - T 11-11-2016 IPR031157 Tr-type G domain, conserved site AUP74_RS07350 9940030657c54b50028ae5f16fcd0d66 527 PRINTS PR00315 GTP-binding elongation factor signature 100 111 5.2E-11 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AUP74_RS07350 9940030657c54b50028ae5f16fcd0d66 527 PRINTS PR00315 GTP-binding elongation factor signature 136 145 5.2E-11 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AUP74_RS07350 9940030657c54b50028ae5f16fcd0d66 527 PRINTS PR00315 GTP-binding elongation factor signature 15 28 5.2E-11 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AUP74_RS07350 9940030657c54b50028ae5f16fcd0d66 527 PRINTS PR00315 GTP-binding elongation factor signature 64 72 5.2E-11 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AUP74_RS07350 9940030657c54b50028ae5f16fcd0d66 527 PRINTS PR00315 GTP-binding elongation factor signature 84 94 5.2E-11 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AUP74_RS07350 9940030657c54b50028ae5f16fcd0d66 527 SUPERFAMILY SSF52540 11 275 6.75E-84 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS07350 9940030657c54b50028ae5f16fcd0d66 527 Pfam PF16658 Class II release factor RF3, C-terminal domain 385 511 7.1E-47 T 11-11-2016 IPR032090 Peptide chain release factor 3, C-terminal AUP74_RS07350 9940030657c54b50028ae5f16fcd0d66 527 SUPERFAMILY SSF50447 260 391 3.77E-29 T 11-11-2016 IPR009000 Translation protein, beta-barrel domain AUP74_RS07350 9940030657c54b50028ae5f16fcd0d66 527 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 17 147 1.4E-17 T 11-11-2016 IPR005225 Small GTP-binding protein domain GO:0005525 AUP74_RS07350 9940030657c54b50028ae5f16fcd0d66 527 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 7 527 1.4E-265 T 11-11-2016 IPR004548 Peptide chain release factor 3 GO:0005525|GO:0005737|GO:0006415|GO:0016149 AUP74_RS07350 9940030657c54b50028ae5f16fcd0d66 527 Pfam PF03144 Elongation factor Tu domain 2 312 378 7.0E-10 T 11-11-2016 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AUP74_RS07350 9940030657c54b50028ae5f16fcd0d66 527 Pfam PF00009 Elongation factor Tu GTP binding domain 14 275 7.4E-45 T 11-11-2016 AUP74_RS07350 9940030657c54b50028ae5f16fcd0d66 527 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 4 525 51.057 T 11-11-2016 IPR004548 Peptide chain release factor 3 GO:0005525|GO:0005737|GO:0006415|GO:0016149 AUP74_RS07350 9940030657c54b50028ae5f16fcd0d66 527 Gene3D G3DSA:3.30.70.870 393 462 6.2E-15 T 11-11-2016 AUP74_RS16230 ad67b8da7356429e04883080a3671130 422 Pfam PF00268 Ribonucleotide reductase, small chain 103 390 4.4E-83 T 11-11-2016 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AUP74_RS16230 ad67b8da7356429e04883080a3671130 422 Gene3D G3DSA:1.10.620.20 91 397 1.0E-108 T 11-11-2016 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 AUP74_RS16230 ad67b8da7356429e04883080a3671130 422 PIRSF PIRSF000355 77 422 1.5E-138 T 11-11-2016 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AUP74_RS16230 ad67b8da7356429e04883080a3671130 422 SUPERFAMILY SSF47240 68 396 9.28E-98 T 11-11-2016 IPR009078 Ferritin-like superfamily AUP74_RS12000 cef5deffa6d2bd9094a3ac1653e4f4a1 214 Gene3D G3DSA:1.10.357.10 5 210 1.9E-33 T 11-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 AUP74_RS12000 cef5deffa6d2bd9094a3ac1653e4f4a1 214 SUPERFAMILY SSF48498 86 212 2.93E-32 T 11-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AUP74_RS12000 cef5deffa6d2bd9094a3ac1653e4f4a1 214 SUPERFAMILY SSF46689 5 78 1.8E-17 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS12000 cef5deffa6d2bd9094a3ac1653e4f4a1 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 1.5E-12 T 11-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AUP74_RS12000 cef5deffa6d2bd9094a3ac1653e4f4a1 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 7.7E-6 T 11-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AUP74_RS12000 cef5deffa6d2bd9094a3ac1653e4f4a1 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 7.7E-6 T 11-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AUP74_RS14150 9477bc039ce724096203ce179a883ca2 395 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 11-11-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 AUP74_RS14150 9477bc039ce724096203ce179a883ca2 395 Gene3D G3DSA:3.90.1150.10 252 385 3.1E-38 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS14150 9477bc039ce724096203ce179a883ca2 395 Gene3D G3DSA:3.40.640.10 47 251 5.1E-70 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AUP74_RS14150 9477bc039ce724096203ce179a883ca2 395 Pfam PF00155 Aminotransferase class I and II 33 382 9.0E-72 T 11-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AUP74_RS14150 9477bc039ce724096203ce179a883ca2 395 SUPERFAMILY SSF53383 20 386 4.65E-111 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase AUP74_RS16685 d06fcaba3b2619197fb61f331fd047a1 74 SUPERFAMILY SSF57716 12 64 7.98E-21 T 11-11-2016 AUP74_RS16685 d06fcaba3b2619197fb61f331fd047a1 74 Pfam PF03884 Domain of unknown function (DUF329) 13 61 4.4E-26 T 11-11-2016 IPR005584 DNA gyrase inhibitor YacG GO:0008270 AUP74_RS16685 d06fcaba3b2619197fb61f331fd047a1 74 Gene3D G3DSA:3.30.50.10 6 64 5.9E-26 T 11-11-2016 IPR013088 Zinc finger, NHR/GATA-type GO:0006355|GO:0008270 AUP74_RS16685 d06fcaba3b2619197fb61f331fd047a1 74 Hamap MF_00649 DNA gyrase inhibitor YacG [yacG]. 9 68 19.803 T 11-11-2016 IPR005584 DNA gyrase inhibitor YacG GO:0008270 AUP74_RS04155 77adf83c309803c2fcbac16c38001da8 431 Gene3D G3DSA:1.10.287.130 194 253 8.2E-22 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS04155 77adf83c309803c2fcbac16c38001da8 431 Gene3D G3DSA:3.30.450.20 97 193 8.4E-7 T 11-11-2016 AUP74_RS04155 77adf83c309803c2fcbac16c38001da8 431 SUPERFAMILY SSF55874 257 421 1.57E-40 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS04155 77adf83c309803c2fcbac16c38001da8 431 SUPERFAMILY SSF47384 188 267 8.44E-21 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS04155 77adf83c309803c2fcbac16c38001da8 431 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 312 423 9.3E-23 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS04155 77adf83c309803c2fcbac16c38001da8 431 SMART SM00388 202 268 5.7E-22 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS04155 77adf83c309803c2fcbac16c38001da8 431 SMART SM00387 312 424 7.3E-35 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS04155 77adf83c309803c2fcbac16c38001da8 431 Gene3D G3DSA:3.30.565.10 254 421 4.3E-41 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS04155 77adf83c309803c2fcbac16c38001da8 431 Pfam PF00512 His Kinase A (phospho-acceptor) domain 202 267 1.6E-18 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS04155 77adf83c309803c2fcbac16c38001da8 431 SUPERFAMILY SSF55785 85 194 6.7E-6 T 11-11-2016 IPR000014 PAS domain AUP74_RS04155 77adf83c309803c2fcbac16c38001da8 431 Pfam PF11808 Domain of unknown function (DUF3329) 9 88 4.8E-21 T 11-11-2016 IPR021766 Protein of unknown function DUF3329 GO:0004673 AUP74_RS04155 77adf83c309803c2fcbac16c38001da8 431 PRINTS PR00344 Bacterial sensor protein C-terminal signature 367 377 1.0E-13 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS04155 77adf83c309803c2fcbac16c38001da8 431 PRINTS PR00344 Bacterial sensor protein C-terminal signature 408 421 1.0E-13 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS04155 77adf83c309803c2fcbac16c38001da8 431 PRINTS PR00344 Bacterial sensor protein C-terminal signature 349 363 1.0E-13 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS04155 77adf83c309803c2fcbac16c38001da8 431 PRINTS PR00344 Bacterial sensor protein C-terminal signature 384 402 1.0E-13 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS04155 77adf83c309803c2fcbac16c38001da8 431 TIGRFAM TIGR02966 phoR_proteo: phosphate regulon sensor kinase PhoR 92 420 8.6E-123 T 11-11-2016 IPR014310 Signal transduction histidine kinase, phosphate regulon sensor PhoR GO:0000155|GO:0000160|GO:0004673|GO:0016021 AUP74_RS11170 11a57411b5fc97f75649b54270e5600e 328 Pfam PF12833 Helix-turn-helix domain 239 317 8.9E-26 T 11-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AUP74_RS11170 11a57411b5fc97f75649b54270e5600e 328 SUPERFAMILY SSF46689 269 320 9.86E-14 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS11170 11a57411b5fc97f75649b54270e5600e 328 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 270 312 - T 11-11-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AUP74_RS11170 11a57411b5fc97f75649b54270e5600e 328 Gene3D G3DSA:3.40.50.880 3 224 5.3E-39 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS11170 11a57411b5fc97f75649b54270e5600e 328 Gene3D G3DSA:1.10.10.60 225 269 4.4E-15 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS11170 11a57411b5fc97f75649b54270e5600e 328 SMART SM00342 233 316 4.2E-32 T 11-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AUP74_RS11170 11a57411b5fc97f75649b54270e5600e 328 SUPERFAMILY SSF52317 1 198 6.87E-36 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS11170 11a57411b5fc97f75649b54270e5600e 328 SUPERFAMILY SSF46689 217 267 7.17E-10 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS11170 11a57411b5fc97f75649b54270e5600e 328 Gene3D G3DSA:1.10.10.60 270 318 3.3E-16 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS11170 11a57411b5fc97f75649b54270e5600e 328 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 285 300 7.0E-7 T 11-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AUP74_RS11170 11a57411b5fc97f75649b54270e5600e 328 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 300 316 7.0E-7 T 11-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AUP74_RS11170 11a57411b5fc97f75649b54270e5600e 328 Pfam PF01965 DJ-1/PfpI family 3 139 1.8E-13 T 11-11-2016 IPR002818 DJ-1/PfpI AUP74_RS01725 4262f6b10a635525ba031ee1d663fef3 318 Gene3D G3DSA:3.40.50.1820 46 313 1.0E-51 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS01725 4262f6b10a635525ba031ee1d663fef3 318 SUPERFAMILY SSF53474 46 314 5.04E-52 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS01725 4262f6b10a635525ba031ee1d663fef3 318 Pfam PF00561 alpha/beta hydrolase fold 69 299 1.9E-17 T 11-11-2016 IPR000073 Alpha/beta hydrolase fold-1 AUP74_RS01725 4262f6b10a635525ba031ee1d663fef3 318 PRINTS PR00111 Alpha/beta hydrolase fold signature 152 165 1.6E-11 T 11-11-2016 IPR000073 Alpha/beta hydrolase fold-1 AUP74_RS01725 4262f6b10a635525ba031ee1d663fef3 318 PRINTS PR00111 Alpha/beta hydrolase fold signature 93 108 1.6E-11 T 11-11-2016 IPR000073 Alpha/beta hydrolase fold-1 AUP74_RS01725 4262f6b10a635525ba031ee1d663fef3 318 PRINTS PR00111 Alpha/beta hydrolase fold signature 254 268 1.6E-11 T 11-11-2016 IPR000073 Alpha/beta hydrolase fold-1 AUP74_RS01725 4262f6b10a635525ba031ee1d663fef3 318 PRINTS PR00111 Alpha/beta hydrolase fold signature 138 151 1.6E-11 T 11-11-2016 IPR000073 Alpha/beta hydrolase fold-1 AUP74_RS11400 16e437fa1f8030de38a2f8e25c864bb7 381 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 41 366 5.2E-64 T 11-11-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 AUP74_RS11400 16e437fa1f8030de38a2f8e25c864bb7 381 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 55 268 6.8E-21 T 11-11-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AUP74_RS11400 16e437fa1f8030de38a2f8e25c864bb7 381 SUPERFAMILY SSF111369 55 230 1.44E-16 T 11-11-2016 AUP74_RS11400 16e437fa1f8030de38a2f8e25c864bb7 381 Gene3D G3DSA:2.40.50.100 67 99 5.1E-13 T 11-11-2016 AUP74_RS11400 16e437fa1f8030de38a2f8e25c864bb7 381 Gene3D G3DSA:2.40.50.100 174 207 5.1E-13 T 11-11-2016 AUP74_RS13910 377f0526fdbd6a823ea07cff2702ee6e 291 Gene3D G3DSA:1.10.10.10 3 76 2.0E-25 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS13910 377f0526fdbd6a823ea07cff2702ee6e 291 SUPERFAMILY SSF46689 2 76 2.15E-19 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS13910 377f0526fdbd6a823ea07cff2702ee6e 291 Pfam PF01418 Helix-turn-helix domain, rpiR family 1 75 5.6E-23 T 11-11-2016 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 AUP74_RS13910 377f0526fdbd6a823ea07cff2702ee6e 291 Gene3D G3DSA:3.40.50.10490 108 267 2.3E-33 T 11-11-2016 AUP74_RS13910 377f0526fdbd6a823ea07cff2702ee6e 291 SUPERFAMILY SSF53697 108 274 7.31E-33 T 11-11-2016 AUP74_RS13910 377f0526fdbd6a823ea07cff2702ee6e 291 Pfam PF01380 SIS domain 128 256 7.7E-20 T 11-11-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 AUP74_RS09725 d54eb842fbc8de510d8078f51b36b2ba 422 SUPERFAMILY SSF53383 4 421 1.03E-132 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase AUP74_RS09725 d54eb842fbc8de510d8078f51b36b2ba 422 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 10 419 1.5E-182 T 11-11-2016 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 AUP74_RS09725 d54eb842fbc8de510d8078f51b36b2ba 422 PIRSF PIRSF000521 23 422 3.1E-29 T 11-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AUP74_RS09725 d54eb842fbc8de510d8078f51b36b2ba 422 Pfam PF00202 Aminotransferase class-III 24 419 2.4E-128 T 11-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AUP74_RS09725 d54eb842fbc8de510d8078f51b36b2ba 422 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 1 422 49.307 T 11-11-2016 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 AUP74_RS09725 d54eb842fbc8de510d8078f51b36b2ba 422 Gene3D G3DSA:3.90.1150.10 3 58 3.3E-59 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS09725 d54eb842fbc8de510d8078f51b36b2ba 422 Gene3D G3DSA:3.90.1150.10 330 420 3.3E-59 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS09725 d54eb842fbc8de510d8078f51b36b2ba 422 Gene3D G3DSA:3.40.640.10 59 325 4.1E-91 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AUP74_RS09725 d54eb842fbc8de510d8078f51b36b2ba 422 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 240 277 - T 11-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AUP74_RS01205 b363228eb0f0f8e14cfefd6e2de335af 459 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 7 429 1.2E-160 T 11-11-2016 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 AUP74_RS01205 b363228eb0f0f8e14cfefd6e2de335af 459 PIRSF PIRSF006446 1 452 5.3E-180 T 11-11-2016 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 AUP74_RS02715 7d9626b9f8d349f61673473e30efc2db 308 Gene3D G3DSA:3.40.50.1820 20 292 2.1E-52 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS02715 7d9626b9f8d349f61673473e30efc2db 308 Pfam PF12697 Alpha/beta hydrolase family 34 287 3.1E-13 T 11-11-2016 IPR000073 Alpha/beta hydrolase fold-1 AUP74_RS02715 7d9626b9f8d349f61673473e30efc2db 308 PRINTS PR00412 Epoxide hydrolase signature 237 253 1.7E-8 T 11-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 AUP74_RS02715 7d9626b9f8d349f61673473e30efc2db 308 PRINTS PR00412 Epoxide hydrolase signature 270 292 1.7E-8 T 11-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 AUP74_RS02715 7d9626b9f8d349f61673473e30efc2db 308 PRINTS PR00412 Epoxide hydrolase signature 102 115 1.7E-8 T 11-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 AUP74_RS02715 7d9626b9f8d349f61673473e30efc2db 308 PRINTS PR00412 Epoxide hydrolase signature 38 56 1.7E-8 T 11-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 AUP74_RS02715 7d9626b9f8d349f61673473e30efc2db 308 SUPERFAMILY SSF53474 14 292 1.52E-50 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS07985 b949158c3900dddf71f83a032d5ef941 1076 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 709 723 - T 11-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AUP74_RS07985 b949158c3900dddf71f83a032d5ef941 1076 Gene3D G3DSA:3.30.1490.20 686 745 7.2E-25 T 11-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 AUP74_RS07985 b949158c3900dddf71f83a032d5ef941 1076 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 427 547 3.0E-39 T 11-11-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 AUP74_RS07985 b949158c3900dddf71f83a032d5ef941 1076 SUPERFAMILY SSF56059 673 933 3.36E-102 T 11-11-2016 AUP74_RS07985 b949158c3900dddf71f83a032d5ef941 1076 SUPERFAMILY SSF52440 1 127 4.75E-49 T 11-11-2016 IPR016185 Pre-ATP-grasp domain AUP74_RS07985 b949158c3900dddf71f83a032d5ef941 1076 Gene3D G3DSA:3.30.470.20 746 934 2.9E-75 T 11-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 AUP74_RS07985 b949158c3900dddf71f83a032d5ef941 1076 Gene3D G3DSA:3.30.470.20 200 399 7.3E-76 T 11-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 AUP74_RS07985 b949158c3900dddf71f83a032d5ef941 1076 SUPERFAMILY SSF48108 396 554 8.24E-52 T 11-11-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 AUP74_RS07985 b949158c3900dddf71f83a032d5ef941 1076 SUPERFAMILY SSF56059 128 401 1.94E-108 T 11-11-2016 AUP74_RS07985 b949158c3900dddf71f83a032d5ef941 1076 Pfam PF02142 MGS-like domain 956 1041 1.5E-22 T 11-11-2016 IPR011607 Methylglyoxal synthase-like domain AUP74_RS07985 b949158c3900dddf71f83a032d5ef941 1076 SMART SM01096 424 547 3.5E-72 T 11-11-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 AUP74_RS07985 b949158c3900dddf71f83a032d5ef941 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 380 398 3.9E-66 T 11-11-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 AUP74_RS07985 b949158c3900dddf71f83a032d5ef941 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 3.9E-66 T 11-11-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 AUP74_RS07985 b949158c3900dddf71f83a032d5ef941 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 3.9E-66 T 11-11-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 AUP74_RS07985 b949158c3900dddf71f83a032d5ef941 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 3.9E-66 T 11-11-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 AUP74_RS07985 b949158c3900dddf71f83a032d5ef941 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 3.9E-66 T 11-11-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 AUP74_RS07985 b949158c3900dddf71f83a032d5ef941 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 3.9E-66 T 11-11-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 AUP74_RS07985 b949158c3900dddf71f83a032d5ef941 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 3.9E-66 T 11-11-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 AUP74_RS07985 b949158c3900dddf71f83a032d5ef941 1076 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 11-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AUP74_RS07985 b949158c3900dddf71f83a032d5ef941 1076 Gene3D G3DSA:1.10.1030.10 400 538 3.6E-49 T 11-11-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 AUP74_RS07985 b949158c3900dddf71f83a032d5ef941 1076 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 11-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AUP74_RS07985 b949158c3900dddf71f83a032d5ef941 1076 Gene3D G3DSA:3.40.50.20 539 662 1.3E-61 T 11-11-2016 IPR016185 Pre-ATP-grasp domain AUP74_RS07985 b949158c3900dddf71f83a032d5ef941 1076 SMART SM00851 955 1041 5.4E-37 T 11-11-2016 IPR011607 Methylglyoxal synthase-like domain AUP74_RS07985 b949158c3900dddf71f83a032d5ef941 1076 Gene3D G3DSA:3.40.50.1380 938 1071 2.5E-45 T 11-11-2016 IPR011607 Methylglyoxal synthase-like domain AUP74_RS07985 b949158c3900dddf71f83a032d5ef941 1076 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 838 845 - T 11-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AUP74_RS07985 b949158c3900dddf71f83a032d5ef941 1076 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1062 13.083 T 11-11-2016 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 AUP74_RS07985 b949158c3900dddf71f83a032d5ef941 1076 SUPERFAMILY SSF52335 936 1071 6.54E-42 T 11-11-2016 IPR011607 Methylglyoxal synthase-like domain AUP74_RS07985 b949158c3900dddf71f83a032d5ef941 1076 Gene3D G3DSA:3.40.50.20 3 108 1.2E-44 T 11-11-2016 IPR016185 Pre-ATP-grasp domain AUP74_RS07985 b949158c3900dddf71f83a032d5ef941 1076 SUPERFAMILY SSF52440 557 675 1.15E-49 T 11-11-2016 IPR016185 Pre-ATP-grasp domain AUP74_RS07985 b949158c3900dddf71f83a032d5ef941 1076 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 673 875 2.7E-33 T 11-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AUP74_RS07985 b949158c3900dddf71f83a032d5ef941 1076 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 1.9E-71 T 11-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AUP74_RS07985 b949158c3900dddf71f83a032d5ef941 1076 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1052 0.0 T 11-11-2016 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 AUP74_RS07985 b949158c3900dddf71f83a032d5ef941 1076 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1067 13.512 T 11-11-2016 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 AUP74_RS07985 b949158c3900dddf71f83a032d5ef941 1076 Gene3D G3DSA:3.30.1490.20 141 199 1.1E-23 T 11-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 AUP74_RS05940 45f79e693743844e5fadb006c618e97c 237 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 130 222 7.9E-11 T 11-11-2016 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 AUP74_RS05940 45f79e693743844e5fadb006c618e97c 237 SMART SM00702 3 223 3.2E-7 T 11-11-2016 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 AUP74_RS05215 7e1508c44b3c21e867e623207375899e 589 Pfam PF05960 Bacterial protein of unknown function (DUF885) 47 579 1.9E-173 T 11-11-2016 IPR010281 Protein of unknown function DUF885 AUP74_RS07905 1ea42c889275523e7ee9f9abb0b0f3a2 575 SUPERFAMILY SSF55826 218 392 5.23E-30 T 11-11-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 AUP74_RS07905 1ea42c889275523e7ee9f9abb0b0f3a2 575 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 4.0E-20 T 11-11-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 AUP74_RS07905 1ea42c889275523e7ee9f9abb0b0f3a2 575 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 4.0E-20 T 11-11-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 AUP74_RS07905 1ea42c889275523e7ee9f9abb0b0f3a2 575 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 4.0E-20 T 11-11-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 AUP74_RS07905 1ea42c889275523e7ee9f9abb0b0f3a2 575 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 4.0E-20 T 11-11-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 AUP74_RS07905 1ea42c889275523e7ee9f9abb0b0f3a2 575 Gene3D G3DSA:3.30.930.10 12 234 3.2E-109 T 11-11-2016 AUP74_RS07905 1ea42c889275523e7ee9f9abb0b0f3a2 575 Gene3D G3DSA:3.30.930.10 391 473 3.2E-109 T 11-11-2016 AUP74_RS07905 1ea42c889275523e7ee9f9abb0b0f3a2 575 Pfam PF03129 Anticodon binding domain 477 571 2.1E-14 T 11-11-2016 IPR004154 Anticodon-binding AUP74_RS07905 1ea42c889275523e7ee9f9abb0b0f3a2 575 SUPERFAMILY SSF52954 466 574 7.25E-27 T 11-11-2016 IPR004154 Anticodon-binding AUP74_RS07905 1ea42c889275523e7ee9f9abb0b0f3a2 575 PIRSF PIRSF001535 1 575 1.1E-267 T 11-11-2016 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 AUP74_RS07905 1ea42c889275523e7ee9f9abb0b0f3a2 575 SUPERFAMILY SSF55681 409 480 9.96E-107 T 11-11-2016 AUP74_RS07905 1ea42c889275523e7ee9f9abb0b0f3a2 575 SUPERFAMILY SSF55681 10 237 9.96E-107 T 11-11-2016 AUP74_RS07905 1ea42c889275523e7ee9f9abb0b0f3a2 575 Gene3D G3DSA:3.90.960.10 254 390 2.5E-32 T 11-11-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 AUP74_RS07905 1ea42c889275523e7ee9f9abb0b0f3a2 575 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 461 3.7E-49 T 11-11-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS07905 1ea42c889275523e7ee9f9abb0b0f3a2 575 Gene3D G3DSA:3.40.50.800 474 573 6.8E-25 T 11-11-2016 IPR004154 Anticodon-binding AUP74_RS07905 1ea42c889275523e7ee9f9abb0b0f3a2 575 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 574 41.566 T 11-11-2016 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 AUP74_RS07905 1ea42c889275523e7ee9f9abb0b0f3a2 575 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 571 4.8E-243 T 11-11-2016 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 AUP74_RS07905 1ea42c889275523e7ee9f9abb0b0f3a2 575 Pfam PF04073 Aminoacyl-tRNA editing domain 257 377 6.8E-25 T 11-11-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 AUP74_RS07535 80182974542dbe7b51ce2beaa9ab5718 150 SUPERFAMILY SSF52335 7 147 4.84E-54 T 11-11-2016 IPR011607 Methylglyoxal synthase-like domain AUP74_RS07535 80182974542dbe7b51ce2beaa9ab5718 150 Gene3D G3DSA:3.40.50.1380 6 149 3.3E-61 T 11-11-2016 IPR011607 Methylglyoxal synthase-like domain AUP74_RS07535 80182974542dbe7b51ce2beaa9ab5718 150 Pfam PF02142 MGS-like domain 26 117 3.9E-17 T 11-11-2016 IPR011607 Methylglyoxal synthase-like domain AUP74_RS07535 80182974542dbe7b51ce2beaa9ab5718 150 ProSitePatterns PS01335 Methylglyoxal synthase active site. 65 73 - T 11-11-2016 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 AUP74_RS07535 80182974542dbe7b51ce2beaa9ab5718 150 SMART SM00851 25 118 5.6E-26 T 11-11-2016 IPR011607 Methylglyoxal synthase-like domain AUP74_RS07535 80182974542dbe7b51ce2beaa9ab5718 150 TIGRFAM TIGR00160 MGSA: methylglyoxal synthase 11 149 5.3E-58 T 11-11-2016 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 AUP74_RS07535 80182974542dbe7b51ce2beaa9ab5718 150 Hamap MF_00549 Methylglyoxal synthase [mgsA]. 12 131 35.934 T 11-11-2016 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 AUP74_RS07535 80182974542dbe7b51ce2beaa9ab5718 150 PIRSF PIRSF006614 8 150 1.0E-60 T 11-11-2016 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 AUP74_RS05220 8b42708663f5320d707727a14d0b5dc8 748 Gene3D G3DSA:3.30.565.10 18 228 1.8E-27 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS05220 8b42708663f5320d707727a14d0b5dc8 748 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 31 147 4.1E-25 T 11-11-2016 AUP74_RS05220 8b42708663f5320d707727a14d0b5dc8 748 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 636 745 1.1E-12 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS05220 8b42708663f5320d707727a14d0b5dc8 748 PRINTS PR00344 Bacterial sensor protein C-terminal signature 732 745 1.5E-7 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS05220 8b42708663f5320d707727a14d0b5dc8 748 PRINTS PR00344 Bacterial sensor protein C-terminal signature 677 691 1.5E-7 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS05220 8b42708663f5320d707727a14d0b5dc8 748 PRINTS PR00344 Bacterial sensor protein C-terminal signature 695 705 1.5E-7 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS05220 8b42708663f5320d707727a14d0b5dc8 748 PRINTS PR00344 Bacterial sensor protein C-terminal signature 706 724 1.5E-7 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS05220 8b42708663f5320d707727a14d0b5dc8 748 SUPERFAMILY SSF55874 604 744 1.83E-22 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS05220 8b42708663f5320d707727a14d0b5dc8 748 SMART SM00387 635 748 1.2E-16 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS05220 8b42708663f5320d707727a14d0b5dc8 748 SUPERFAMILY SSF55874 18 139 1.02E-23 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS05220 8b42708663f5320d707727a14d0b5dc8 748 Gene3D G3DSA:3.30.565.10 598 744 3.6E-24 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS11295 72b76bc661ab2af36a6ad19b7c85781a 740 Pfam PF13361 UvrD-like helicase C-terminal domain 495 617 1.8E-20 T 11-11-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 AUP74_RS11295 72b76bc661ab2af36a6ad19b7c85781a 740 Pfam PF00580 UvrD/REP helicase N-terminal domain 6 269 6.1E-31 T 11-11-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 AUP74_RS11295 72b76bc661ab2af36a6ad19b7c85781a 740 Gene3D G3DSA:3.40.50.300 555 644 9.4E-40 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11295 72b76bc661ab2af36a6ad19b7c85781a 740 Gene3D G3DSA:3.40.50.300 286 395 9.4E-40 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11295 72b76bc661ab2af36a6ad19b7c85781a 740 SUPERFAMILY SSF52540 5 642 5.33E-97 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11295 72b76bc661ab2af36a6ad19b7c85781a 740 Gene3D G3DSA:3.40.50.300 5 143 7.2E-49 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11295 72b76bc661ab2af36a6ad19b7c85781a 740 Gene3D G3DSA:3.40.50.300 177 278 7.2E-49 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05190 530fd8f8d693433ce9011b04c5961d41 495 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 39 488 8.6E-87 T 11-11-2016 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 AUP74_RS05190 530fd8f8d693433ce9011b04c5961d41 495 Pfam PF00939 Sodium:sulfate symporter transmembrane region 27 489 6.2E-81 T 11-11-2016 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 AUP74_RS05190 530fd8f8d693433ce9011b04c5961d41 495 ProSitePatterns PS01271 Sodium:sulfate symporter family signature. 439 455 - T 11-11-2016 IPR031312 Sodium/sulphate symporter, conserved site Reactome: R-HSA-433137 AUP74_RS04785 c92b1812b546aa80c223f730258741ab 909 SMART SM00482 667 873 1.5E-122 T 11-11-2016 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS04785 c92b1812b546aa80c223f730258741ab 909 Gene3D G3DSA:3.40.50.1010 10 188 1.4E-68 T 11-11-2016 IPR029060 PIN domain-like AUP74_RS04785 c92b1812b546aa80c223f730258741ab 909 SUPERFAMILY SSF88723 9 172 2.07E-55 T 11-11-2016 IPR029060 PIN domain-like AUP74_RS04785 c92b1812b546aa80c223f730258741ab 909 TIGRFAM TIGR00593 pola: DNA polymerase I 11 909 7.5E-293 T 11-11-2016 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS04785 c92b1812b546aa80c223f730258741ab 909 SUPERFAMILY SSF53098 314 499 1.43E-56 T 11-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 AUP74_RS04785 c92b1812b546aa80c223f730258741ab 909 PRINTS PR00868 DNA-polymerase family A (pol I) signature 711 724 1.7E-79 T 11-11-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS04785 c92b1812b546aa80c223f730258741ab 909 PRINTS PR00868 DNA-polymerase family A (pol I) signature 772 783 1.7E-79 T 11-11-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS04785 c92b1812b546aa80c223f730258741ab 909 PRINTS PR00868 DNA-polymerase family A (pol I) signature 735 760 1.7E-79 T 11-11-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS04785 c92b1812b546aa80c223f730258741ab 909 PRINTS PR00868 DNA-polymerase family A (pol I) signature 681 704 1.7E-79 T 11-11-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS04785 c92b1812b546aa80c223f730258741ab 909 PRINTS PR00868 DNA-polymerase family A (pol I) signature 794 805 1.7E-79 T 11-11-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS04785 c92b1812b546aa80c223f730258741ab 909 PRINTS PR00868 DNA-polymerase family A (pol I) signature 856 869 1.7E-79 T 11-11-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS04785 c92b1812b546aa80c223f730258741ab 909 PRINTS PR00868 DNA-polymerase family A (pol I) signature 659 674 1.7E-79 T 11-11-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS04785 c92b1812b546aa80c223f730258741ab 909 PRINTS PR00868 DNA-polymerase family A (pol I) signature 826 842 1.7E-79 T 11-11-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS04785 c92b1812b546aa80c223f730258741ab 909 PRINTS PR00868 DNA-polymerase family A (pol I) signature 636 658 1.7E-79 T 11-11-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS04785 c92b1812b546aa80c223f730258741ab 909 SUPERFAMILY SSF56672 504 909 3.67E-161 T 11-11-2016 AUP74_RS04785 c92b1812b546aa80c223f730258741ab 909 SMART SM00474 311 498 1.5E-43 T 11-11-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 AUP74_RS04785 c92b1812b546aa80c223f730258741ab 909 Gene3D G3DSA:1.20.1060.10 524 644 3.2E-37 T 11-11-2016 AUP74_RS04785 c92b1812b546aa80c223f730258741ab 909 Gene3D G3DSA:3.30.70.370 800 909 1.6E-68 T 11-11-2016 AUP74_RS04785 c92b1812b546aa80c223f730258741ab 909 Gene3D G3DSA:3.30.70.370 645 692 1.6E-68 T 11-11-2016 AUP74_RS04785 c92b1812b546aa80c223f730258741ab 909 Pfam PF00476 DNA polymerase family A 532 907 2.0E-159 T 11-11-2016 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS04785 c92b1812b546aa80c223f730258741ab 909 Gene3D G3DSA:1.10.150.20 189 255 2.3E-25 T 11-11-2016 AUP74_RS04785 c92b1812b546aa80c223f730258741ab 909 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 173 274 7.8E-29 T 11-11-2016 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 AUP74_RS04785 c92b1812b546aa80c223f730258741ab 909 SMART SM00279 175 210 6.5E-14 T 11-11-2016 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 AUP74_RS04785 c92b1812b546aa80c223f730258741ab 909 Pfam PF01612 3'-5' exonuclease 311 495 1.6E-40 T 11-11-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 AUP74_RS04785 c92b1812b546aa80c223f730258741ab 909 ProSitePatterns PS00447 DNA polymerase family A signature. 735 754 - T 11-11-2016 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS04785 c92b1812b546aa80c223f730258741ab 909 SMART SM00475 9 270 3.4E-119 T 11-11-2016 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 AUP74_RS04785 c92b1812b546aa80c223f730258741ab 909 Gene3D G3DSA:3.30.420.10 309 523 1.6E-85 T 11-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 AUP74_RS04785 c92b1812b546aa80c223f730258741ab 909 Gene3D G3DSA:1.10.150.20 693 799 8.3E-36 T 11-11-2016 AUP74_RS04785 c92b1812b546aa80c223f730258741ab 909 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 11 172 2.8E-53 T 11-11-2016 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 AUP74_RS04785 c92b1812b546aa80c223f730258741ab 909 SUPERFAMILY SSF47807 173 294 1.11E-30 T 11-11-2016 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 AUP74_RS04435 841431559a359ce871b3a81133b02673 268 SUPERFAMILY SSF52540 3 252 3.19E-67 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04435 841431559a359ce871b3a81133b02673 268 Pfam PF13614 AAA domain 3 177 4.4E-61 T 11-11-2016 IPR025669 AAA domain AUP74_RS04435 841431559a359ce871b3a81133b02673 268 Gene3D G3DSA:3.40.50.300 3 251 9.3E-72 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS00280 2f81b53be55c6cb68b4db5f0d2b53772 554 Gene3D G3DSA:3.40.50.10490 1 98 1.2E-151 T 11-11-2016 AUP74_RS00280 2f81b53be55c6cb68b4db5f0d2b53772 554 Gene3D G3DSA:3.40.50.10490 260 497 1.2E-151 T 11-11-2016 AUP74_RS00280 2f81b53be55c6cb68b4db5f0d2b53772 554 Gene3D G3DSA:3.40.50.10490 143 181 1.2E-151 T 11-11-2016 AUP74_RS00280 2f81b53be55c6cb68b4db5f0d2b53772 554 PRINTS PR00662 Glucose-6-phosphate isomerase signature 494 507 5.9E-53 T 11-11-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS00280 2f81b53be55c6cb68b4db5f0d2b53772 554 PRINTS PR00662 Glucose-6-phosphate isomerase signature 335 356 5.9E-53 T 11-11-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS00280 2f81b53be55c6cb68b4db5f0d2b53772 554 PRINTS PR00662 Glucose-6-phosphate isomerase signature 480 494 5.9E-53 T 11-11-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS00280 2f81b53be55c6cb68b4db5f0d2b53772 554 PRINTS PR00662 Glucose-6-phosphate isomerase signature 462 480 5.9E-53 T 11-11-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS00280 2f81b53be55c6cb68b4db5f0d2b53772 554 PRINTS PR00662 Glucose-6-phosphate isomerase signature 146 165 5.9E-53 T 11-11-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS00280 2f81b53be55c6cb68b4db5f0d2b53772 554 PRINTS PR00662 Glucose-6-phosphate isomerase signature 258 276 5.9E-53 T 11-11-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS00280 2f81b53be55c6cb68b4db5f0d2b53772 554 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 494 511 - T 11-11-2016 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS00280 2f81b53be55c6cb68b4db5f0d2b53772 554 Pfam PF00342 Phosphoglucose isomerase 48 537 1.4E-189 T 11-11-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS00280 2f81b53be55c6cb68b4db5f0d2b53772 554 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 42 521 39.336 T 11-11-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS00280 2f81b53be55c6cb68b4db5f0d2b53772 554 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 262 275 - T 11-11-2016 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS00280 2f81b53be55c6cb68b4db5f0d2b53772 554 SUPERFAMILY SSF53697 1 543 1.08E-194 T 11-11-2016 AUP74_RS00280 2f81b53be55c6cb68b4db5f0d2b53772 554 Gene3D G3DSA:1.10.1390.10 499 544 1.6E-14 T 11-11-2016 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS05370 2504dc737c155a9513a76d2eb47940c4 166 Pfam PF00583 Acetyltransferase (GNAT) family 59 132 4.0E-14 T 11-11-2016 IPR000182 GNAT domain GO:0008080 AUP74_RS05370 2504dc737c155a9513a76d2eb47940c4 166 Gene3D G3DSA:3.40.630.30 7 142 2.0E-26 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS05370 2504dc737c155a9513a76d2eb47940c4 166 SUPERFAMILY SSF55729 4 140 1.83E-23 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS06545 f2146d36d3ed15565eb2f0b29c54bf58 192 Pfam PF03923 Uncharacterized lipoprotein 67 189 4.5E-17 T 11-11-2016 IPR005619 Uncharacterised protein family, YajG AUP74_RS02980 fa7ac2db5fa3590ee674bddc02cbdc95 667 SUPERFAMILY SSF52518 348 528 1.44E-65 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS02980 fa7ac2db5fa3590ee674bddc02cbdc95 667 Gene3D G3DSA:3.40.50.970 331 538 1.0E-75 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS02980 fa7ac2db5fa3590ee674bddc02cbdc95 667 Gene3D G3DSA:3.40.50.970 9 326 1.8E-133 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS02980 fa7ac2db5fa3590ee674bddc02cbdc95 667 SUPERFAMILY SSF52922 537 667 3.28E-41 T 11-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 AUP74_RS02980 fa7ac2db5fa3590ee674bddc02cbdc95 667 Gene3D G3DSA:3.40.50.920 543 666 2.2E-46 T 11-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 AUP74_RS02980 fa7ac2db5fa3590ee674bddc02cbdc95 667 TIGRFAM TIGR00232 tktlase_bact: transketolase 10 666 0.0 T 11-11-2016 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 AUP74_RS02980 fa7ac2db5fa3590ee674bddc02cbdc95 667 Pfam PF02780 Transketolase, C-terminal domain 545 658 6.3E-11 T 11-11-2016 IPR033248 Transketolase, C-terminal domain AUP74_RS02980 fa7ac2db5fa3590ee674bddc02cbdc95 667 Pfam PF02779 Transketolase, pyrimidine binding domain 358 528 1.4E-43 T 11-11-2016 IPR005475 Transketolase-like, pyrimidine-binding domain AUP74_RS02980 fa7ac2db5fa3590ee674bddc02cbdc95 667 ProSitePatterns PS00802 Transketolase signature 2. 472 488 - T 11-11-2016 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AUP74_RS02980 fa7ac2db5fa3590ee674bddc02cbdc95 667 ProSitePatterns PS00801 Transketolase signature 1. 16 36 - T 11-11-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AUP74_RS02980 fa7ac2db5fa3590ee674bddc02cbdc95 667 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 8 338 6.3E-166 T 11-11-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AUP74_RS02980 fa7ac2db5fa3590ee674bddc02cbdc95 667 SUPERFAMILY SSF52518 10 334 3.48E-121 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS02980 fa7ac2db5fa3590ee674bddc02cbdc95 667 SMART SM00861 359 531 4.6E-65 T 11-11-2016 IPR005475 Transketolase-like, pyrimidine-binding domain AUP74_RS04265 5ca6e70a554c748ff4fa80f922b39c2f 378 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 52 339 4.9E-62 T 11-11-2016 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 AUP74_RS04265 5ca6e70a554c748ff4fa80f922b39c2f 378 PIRSF PIRSF039026 19 373 1.5E-137 T 11-11-2016 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like AUP74_RS04265 5ca6e70a554c748ff4fa80f922b39c2f 378 SUPERFAMILY SSF53850 156 295 3.11E-6 T 11-11-2016 AUP74_RS04405 1ab8acbfaaa6f751c0a34a8fb3004602 178 PRINTS PR00125 ATP synthase delta subunit signature 7 26 3.4E-25 T 11-11-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 AUP74_RS04405 1ab8acbfaaa6f751c0a34a8fb3004602 178 PRINTS PR00125 ATP synthase delta subunit signature 136 151 3.4E-25 T 11-11-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 AUP74_RS04405 1ab8acbfaaa6f751c0a34a8fb3004602 178 PRINTS PR00125 ATP synthase delta subunit signature 86 100 3.4E-25 T 11-11-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 AUP74_RS04405 1ab8acbfaaa6f751c0a34a8fb3004602 178 PRINTS PR00125 ATP synthase delta subunit signature 75 86 3.4E-25 T 11-11-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 AUP74_RS04405 1ab8acbfaaa6f751c0a34a8fb3004602 178 PRINTS PR00125 ATP synthase delta subunit signature 151 169 3.4E-25 T 11-11-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 AUP74_RS04405 1ab8acbfaaa6f751c0a34a8fb3004602 178 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 138 157 - T 11-11-2016 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210 AUP74_RS04405 1ab8acbfaaa6f751c0a34a8fb3004602 178 Pfam PF00213 ATP synthase delta (OSCP) subunit 7 176 9.5E-55 T 11-11-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 AUP74_RS04405 1ab8acbfaaa6f751c0a34a8fb3004602 178 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 8 175 6.4E-49 T 11-11-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 AUP74_RS04405 1ab8acbfaaa6f751c0a34a8fb3004602 178 Gene3D G3DSA:1.10.520.20 2 105 3.1E-32 T 11-11-2016 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210 AUP74_RS04405 1ab8acbfaaa6f751c0a34a8fb3004602 178 SUPERFAMILY SSF47928 3 106 8.5E-25 T 11-11-2016 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210 AUP74_RS04405 1ab8acbfaaa6f751c0a34a8fb3004602 178 Hamap MF_01416 ATP synthase subunit delta [atpD]. 3 178 20.022 T 11-11-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 AUP74_RS16550 eaac041f5c58330f753e1a57f06ad35e 480 SUPERFAMILY SSF55424 350 474 1.12E-41 T 11-11-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 AUP74_RS16550 eaac041f5c58330f753e1a57f06ad35e 480 Gene3D G3DSA:3.50.50.60 2 147 1.6E-39 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS16550 eaac041f5c58330f753e1a57f06ad35e 480 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 287 2.7E-37 T 11-11-2016 AUP74_RS16550 eaac041f5c58330f753e1a57f06ad35e 480 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 2.7E-37 T 11-11-2016 AUP74_RS16550 eaac041f5c58330f753e1a57f06ad35e 480 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 183 201 2.7E-37 T 11-11-2016 AUP74_RS16550 eaac041f5c58330f753e1a57f06ad35e 480 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 2.7E-37 T 11-11-2016 AUP74_RS16550 eaac041f5c58330f753e1a57f06ad35e 480 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 300 322 2.7E-37 T 11-11-2016 AUP74_RS16550 eaac041f5c58330f753e1a57f06ad35e 480 Gene3D G3DSA:3.30.390.30 342 472 2.1E-47 T 11-11-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AUP74_RS16550 eaac041f5c58330f753e1a57f06ad35e 480 Gene3D G3DSA:3.50.50.60 148 341 4.2E-51 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS16550 eaac041f5c58330f753e1a57f06ad35e 480 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 335 7.5E-69 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS16550 eaac041f5c58330f753e1a57f06ad35e 480 PIRSF PIRSF000350 1 472 3.0E-86 T 11-11-2016 AUP74_RS16550 eaac041f5c58330f753e1a57f06ad35e 480 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 354 463 5.9E-38 T 11-11-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AUP74_RS16550 eaac041f5c58330f753e1a57f06ad35e 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 437 457 3.5E-78 T 11-11-2016 AUP74_RS16550 eaac041f5c58330f753e1a57f06ad35e 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 183 208 3.5E-78 T 11-11-2016 AUP74_RS16550 eaac041f5c58330f753e1a57f06ad35e 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 3.5E-78 T 11-11-2016 AUP74_RS16550 eaac041f5c58330f753e1a57f06ad35e 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 45 60 3.5E-78 T 11-11-2016 AUP74_RS16550 eaac041f5c58330f753e1a57f06ad35e 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 156 3.5E-78 T 11-11-2016 AUP74_RS16550 eaac041f5c58330f753e1a57f06ad35e 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 272 286 3.5E-78 T 11-11-2016 AUP74_RS16550 eaac041f5c58330f753e1a57f06ad35e 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 315 322 3.5E-78 T 11-11-2016 AUP74_RS16550 eaac041f5c58330f753e1a57f06ad35e 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 350 371 3.5E-78 T 11-11-2016 AUP74_RS16550 eaac041f5c58330f753e1a57f06ad35e 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 415 430 3.5E-78 T 11-11-2016 AUP74_RS16550 eaac041f5c58330f753e1a57f06ad35e 480 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 46 56 - T 11-11-2016 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 AUP74_RS16550 eaac041f5c58330f753e1a57f06ad35e 480 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 473 1.5E-161 T 11-11-2016 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 AUP74_RS16550 eaac041f5c58330f753e1a57f06ad35e 480 SUPERFAMILY SSF51905 1 345 2.06E-64 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS04630 b55538475487c835e7515ab7f5960790 475 Gene3D G3DSA:3.40.309.10 257 443 4.4E-57 T 11-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 AUP74_RS04630 b55538475487c835e7515ab7f5960790 475 Pfam PF00171 Aldehyde dehydrogenase family 13 467 4.2E-156 T 11-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 AUP74_RS04630 b55538475487c835e7515ab7f5960790 475 SUPERFAMILY SSF53720 4 468 3.4E-155 T 11-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AUP74_RS04630 b55538475487c835e7515ab7f5960790 475 Gene3D G3DSA:3.40.605.10 4 256 4.1E-93 T 11-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AUP74_RS06550 6fbe43cc21d381a03cba5f6550974abc 590 SMART SM00267 154 326 7.7E-56 T 11-11-2016 IPR000160 GGDEF domain AUP74_RS06550 6fbe43cc21d381a03cba5f6550974abc 590 Gene3D G3DSA:3.30.450.20 36 152 2.2E-6 T 11-11-2016 AUP74_RS06550 6fbe43cc21d381a03cba5f6550974abc 590 Pfam PF00563 EAL domain 344 577 1.3E-64 T 11-11-2016 IPR001633 EAL domain AUP74_RS06550 6fbe43cc21d381a03cba5f6550974abc 590 SUPERFAMILY SSF55073 170 328 2.9E-42 T 11-11-2016 IPR029787 Nucleotide cyclase AUP74_RS06550 6fbe43cc21d381a03cba5f6550974abc 590 Gene3D G3DSA:3.30.70.270 167 329 6.9E-49 T 11-11-2016 AUP74_RS06550 6fbe43cc21d381a03cba5f6550974abc 590 SMART SM00052 337 588 9.1E-76 T 11-11-2016 IPR001633 EAL domain AUP74_RS06550 6fbe43cc21d381a03cba5f6550974abc 590 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 162 325 5.1E-36 T 11-11-2016 IPR000160 GGDEF domain AUP74_RS06550 6fbe43cc21d381a03cba5f6550974abc 590 SUPERFAMILY SSF141868 344 581 7.19E-72 T 11-11-2016 IPR001633 EAL domain AUP74_RS06550 6fbe43cc21d381a03cba5f6550974abc 590 Pfam PF00990 Diguanylate cyclase, GGDEF domain 166 322 5.1E-40 T 11-11-2016 IPR000160 GGDEF domain AUP74_RS06550 6fbe43cc21d381a03cba5f6550974abc 590 Gene3D G3DSA:3.20.20.450 341 582 1.4E-77 T 11-11-2016 IPR001633 EAL domain AUP74_RS02385 86cd99877d532b3b452bf7501b7f11b2 219 Gene3D G3DSA:1.20.1440.100 15 78 1.8E-29 T 11-11-2016 AUP74_RS02385 86cd99877d532b3b452bf7501b7f11b2 219 Gene3D G3DSA:3.40.50.1000 79 218 3.2E-50 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS02385 86cd99877d532b3b452bf7501b7f11b2 219 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 3 191 1.5E-28 T 11-11-2016 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 AUP74_RS02385 86cd99877d532b3b452bf7501b7f11b2 219 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 3 203 9.3E-45 T 11-11-2016 IPR006385 HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial AUP74_RS02385 86cd99877d532b3b452bf7501b7f11b2 219 SUPERFAMILY SSF56784 2 212 1.76E-39 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS02385 86cd99877d532b3b452bf7501b7f11b2 219 Pfam PF12710 haloacid dehalogenase-like hydrolase 4 189 4.6E-39 T 11-11-2016 AUP74_RS00830 2daf34b9757a403ccd17dd93d26c08dc 558 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 11-11-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 AUP74_RS00830 2daf34b9757a403ccd17dd93d26c08dc 558 Pfam PF02817 e3 binding domain 258 292 4.6E-13 T 11-11-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 AUP74_RS00830 2daf34b9757a403ccd17dd93d26c08dc 558 TIGRFAM TIGR01348 PDHac_trf_long: dihydrolipoyllysine-residue acetyltransferase 115 558 6.2E-171 T 11-11-2016 IPR006256 Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex GO:0004742|GO:0006096|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 AUP74_RS00830 2daf34b9757a403ccd17dd93d26c08dc 558 Gene3D G3DSA:4.10.320.10 254 302 1.2E-17 T 11-11-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 AUP74_RS00830 2daf34b9757a403ccd17dd93d26c08dc 558 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 331 557 5.8E-77 T 11-11-2016 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 AUP74_RS00830 2daf34b9757a403ccd17dd93d26c08dc 558 SUPERFAMILY SSF47005 254 297 4.19E-11 T 11-11-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 AUP74_RS00830 2daf34b9757a403ccd17dd93d26c08dc 558 Gene3D G3DSA:2.40.50.100 127 200 1.1E-20 T 11-11-2016 AUP74_RS00830 2daf34b9757a403ccd17dd93d26c08dc 558 Gene3D G3DSA:2.40.50.100 6 79 1.4E-20 T 11-11-2016 AUP74_RS00830 2daf34b9757a403ccd17dd93d26c08dc 558 SUPERFAMILY SSF51230 126 215 1.44E-19 T 11-11-2016 IPR011053 Single hybrid motif AUP74_RS00830 2daf34b9757a403ccd17dd93d26c08dc 558 Gene3D G3DSA:3.30.559.10 323 558 7.8E-84 T 11-11-2016 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 AUP74_RS00830 2daf34b9757a403ccd17dd93d26c08dc 558 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 148 177 - T 11-11-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 AUP74_RS00830 2daf34b9757a403ccd17dd93d26c08dc 558 Pfam PF00364 Biotin-requiring enzyme 5 76 1.6E-19 T 11-11-2016 IPR000089 Biotin/lipoyl attachment AUP74_RS00830 2daf34b9757a403ccd17dd93d26c08dc 558 Pfam PF00364 Biotin-requiring enzyme 126 196 2.8E-19 T 11-11-2016 IPR000089 Biotin/lipoyl attachment AUP74_RS00830 2daf34b9757a403ccd17dd93d26c08dc 558 SUPERFAMILY SSF51230 4 92 9.16E-21 T 11-11-2016 IPR011053 Single hybrid motif AUP74_RS00830 2daf34b9757a403ccd17dd93d26c08dc 558 SUPERFAMILY SSF52777 317 558 4.89E-82 T 11-11-2016 AUP74_RS00545 ad5a5f8a2678df0ab6fbf59831fe594e 172 SUPERFAMILY SSF52091 5 104 5.3E-10 T 11-11-2016 IPR002645 STAS domain AUP74_RS00545 ad5a5f8a2678df0ab6fbf59831fe594e 172 PIRSF PIRSF029548 1 160 9.6E-36 T 11-11-2016 IPR014557 Uncharacterised conserved protein UCP029548, STAS-type AUP74_RS00545 ad5a5f8a2678df0ab6fbf59831fe594e 172 Gene3D G3DSA:3.30.750.24 6 106 9.9E-10 T 11-11-2016 IPR002645 STAS domain AUP74_RS12045 24c49f122765adc5a7e39eb4a983da2d 226 SUPERFAMILY SSF48008 86 223 1.46E-29 T 11-11-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal AUP74_RS12045 24c49f122765adc5a7e39eb4a983da2d 226 Gene3D G3DSA:1.20.120.530 83 225 2.0E-31 T 11-11-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal AUP74_RS12045 24c49f122765adc5a7e39eb4a983da2d 226 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 79 6.5E-15 T 11-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AUP74_RS12045 24c49f122765adc5a7e39eb4a983da2d 226 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 53 3.4E-5 T 11-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AUP74_RS12045 24c49f122765adc5a7e39eb4a983da2d 226 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 69 3.4E-5 T 11-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AUP74_RS12045 24c49f122765adc5a7e39eb4a983da2d 226 Gene3D G3DSA:1.10.10.10 11 79 2.2E-20 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS12045 24c49f122765adc5a7e39eb4a983da2d 226 Pfam PF07729 FCD domain 89 215 2.1E-26 T 11-11-2016 IPR011711 GntR, C-terminal AUP74_RS12045 24c49f122765adc5a7e39eb4a983da2d 226 SMART SM00345 21 79 1.6E-10 T 11-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AUP74_RS12045 24c49f122765adc5a7e39eb4a983da2d 226 SUPERFAMILY SSF46785 13 83 4.1E-18 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS12045 24c49f122765adc5a7e39eb4a983da2d 226 SMART SM00895 89 216 2.3E-26 T 11-11-2016 IPR011711 GntR, C-terminal AUP74_RS08150 56eaa9ec86aeffd03cfe5499bfa217c1 1691 SUPERFAMILY SSF56935 1538 1666 2.88E-5 T 11-11-2016 AUP74_RS08150 56eaa9ec86aeffd03cfe5499bfa217c1 1691 SUPERFAMILY SSF103088 245 358 3.53E-16 T 11-11-2016 IPR006665 OmpA-like domain AUP74_RS08150 56eaa9ec86aeffd03cfe5499bfa217c1 1691 Gene3D G3DSA:2.40.160.60 1197 1356 8.5E-4 T 11-11-2016 AUP74_RS08150 56eaa9ec86aeffd03cfe5499bfa217c1 1691 Gene3D G3DSA:3.30.1330.60 77 194 8.8E-14 T 11-11-2016 IPR006665 OmpA-like domain AUP74_RS08150 56eaa9ec86aeffd03cfe5499bfa217c1 1691 Gene3D G3DSA:3.30.1330.60 239 358 6.7E-16 T 11-11-2016 IPR006665 OmpA-like domain AUP74_RS08150 56eaa9ec86aeffd03cfe5499bfa217c1 1691 SUPERFAMILY SSF103088 77 194 1.29E-11 T 11-11-2016 IPR006665 OmpA-like domain AUP74_RS08150 56eaa9ec86aeffd03cfe5499bfa217c1 1691 SUPERFAMILY SSF56935 1197 1269 3.81E-7 T 11-11-2016 AUP74_RS08150 56eaa9ec86aeffd03cfe5499bfa217c1 1691 SUPERFAMILY SSF56935 1473 1546 3.81E-7 T 11-11-2016 AUP74_RS08150 56eaa9ec86aeffd03cfe5499bfa217c1 1691 SUPERFAMILY SSF56935 1309 1438 3.81E-7 T 11-11-2016 AUP74_RS08150 56eaa9ec86aeffd03cfe5499bfa217c1 1691 Gene3D G3DSA:2.40.160.10 1423 1545 9.3E-5 T 11-11-2016 IPR023614 Porin domain AUP74_RS08150 56eaa9ec86aeffd03cfe5499bfa217c1 1691 Pfam PF00691 OmpA family 86 188 5.9E-6 T 11-11-2016 IPR006665 OmpA-like domain AUP74_RS02520 84dbb1b26530281751ddfef30574978c 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 119 1.4E-37 T 11-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 AUP74_RS02520 84dbb1b26530281751ddfef30574978c 382 SUPERFAMILY SSF47203 229 380 6.77E-49 T 11-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AUP74_RS02520 84dbb1b26530281751ddfef30574978c 382 SUPERFAMILY SSF56645 5 242 6.54E-92 T 11-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 AUP74_RS02520 84dbb1b26530281751ddfef30574978c 382 PIRSF PIRSF016578 2 381 1.8E-17 T 11-11-2016 AUP74_RS02520 84dbb1b26530281751ddfef30574978c 382 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 11-11-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AUP74_RS02520 84dbb1b26530281751ddfef30574978c 382 Gene3D G3DSA:2.40.110.10 123 219 2.3E-43 T 11-11-2016 AUP74_RS02520 84dbb1b26530281751ddfef30574978c 382 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 125 137 - T 11-11-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AUP74_RS02520 84dbb1b26530281751ddfef30574978c 382 Gene3D G3DSA:1.20.140.10 220 381 3.9E-58 T 11-11-2016 AUP74_RS02520 84dbb1b26530281751ddfef30574978c 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 378 1.2E-40 T 11-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AUP74_RS02520 84dbb1b26530281751ddfef30574978c 382 Gene3D G3DSA:1.10.540.10 6 120 5.1E-40 T 11-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 AUP74_RS02520 84dbb1b26530281751ddfef30574978c 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 218 3.5E-27 T 11-11-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 AUP74_RS00700 7e04453c03f26778ff093b46ac8f3390 883 Pfam PF07715 TonB-dependent Receptor Plug Domain 47 160 2.7E-23 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS00700 7e04453c03f26778ff093b46ac8f3390 883 SUPERFAMILY SSF56935 33 225 2.81E-102 T 11-11-2016 AUP74_RS00700 7e04453c03f26778ff093b46ac8f3390 883 SUPERFAMILY SSF56935 269 317 2.81E-102 T 11-11-2016 AUP74_RS00700 7e04453c03f26778ff093b46ac8f3390 883 SUPERFAMILY SSF56935 376 883 2.81E-102 T 11-11-2016 AUP74_RS00700 7e04453c03f26778ff093b46ac8f3390 883 Gene3D G3DSA:2.170.130.10 34 160 2.5E-34 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS00700 7e04453c03f26778ff093b46ac8f3390 883 Pfam PF00593 TonB dependent receptor 567 882 2.3E-31 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS00700 7e04453c03f26778ff093b46ac8f3390 883 Gene3D G3DSA:2.40.170.20 631 883 8.1E-85 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS00700 7e04453c03f26778ff093b46ac8f3390 883 Gene3D G3DSA:2.40.170.20 161 226 8.1E-85 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS00700 7e04453c03f26778ff093b46ac8f3390 883 Gene3D G3DSA:2.40.170.20 378 598 8.1E-85 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS00700 7e04453c03f26778ff093b46ac8f3390 883 Gene3D G3DSA:2.40.170.20 268 308 8.1E-85 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS10510 07f422c63ebae3014a43580d24d9b7b4 74 Pfam PF06794 Uncharacterised protein family (UPF0270) 1 67 2.0E-26 T 11-11-2016 IPR010648 Uncharacterised protein family UPF0270 AUP74_RS10510 07f422c63ebae3014a43580d24d9b7b4 74 SUPERFAMILY SSF118001 1 70 6.54E-24 T 11-11-2016 IPR010648 Uncharacterised protein family UPF0270 AUP74_RS10510 07f422c63ebae3014a43580d24d9b7b4 74 Gene3D G3DSA:1.10.10.610 1 71 1.3E-27 T 11-11-2016 IPR010648 Uncharacterised protein family UPF0270 AUP74_RS10510 07f422c63ebae3014a43580d24d9b7b4 74 ProDom PD026997 UPF0270 YHEU SO0879 3D-STRUCTURE LYASE PLU0398 YPO0179/Y3960/YP0178 ENOLASE HD0737 PSPTO1630 1 65 1.0E-13 T 11-11-2016 IPR010648 Uncharacterised protein family UPF0270 AUP74_RS12835 7f506390c526929230a35fa8db8dd371 94 SMART SM00357 3 67 6.9E-27 T 11-11-2016 IPR011129 Cold shock protein GO:0003676 AUP74_RS12835 7f506390c526929230a35fa8db8dd371 94 TIGRFAM TIGR02381 cspD: cold shock domain protein CspD 1 65 1.2E-35 T 11-11-2016 IPR012751 CspD, cold shock GO:0003676|GO:0005737|GO:0006355|GO:0006950 AUP74_RS12835 7f506390c526929230a35fa8db8dd371 94 PIRSF PIRSF002599 1 90 6.7E-24 T 11-11-2016 IPR012156 Cold shock, CspA GO:0003676 AUP74_RS12835 7f506390c526929230a35fa8db8dd371 94 PRINTS PR00050 Cold shock protein signature 25 34 8.1E-17 T 11-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AUP74_RS12835 7f506390c526929230a35fa8db8dd371 94 PRINTS PR00050 Cold shock protein signature 4 19 8.1E-17 T 11-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AUP74_RS12835 7f506390c526929230a35fa8db8dd371 94 PRINTS PR00050 Cold shock protein signature 40 58 8.1E-17 T 11-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AUP74_RS12835 7f506390c526929230a35fa8db8dd371 94 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 11-11-2016 IPR019844 Cold-shock conserved site AUP74_RS12835 7f506390c526929230a35fa8db8dd371 94 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 1.5E-28 T 11-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AUP74_RS12835 7f506390c526929230a35fa8db8dd371 94 Gene3D G3DSA:2.40.50.140 1 66 2.8E-29 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS12835 7f506390c526929230a35fa8db8dd371 94 SUPERFAMILY SSF50249 1 65 9.79E-24 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS02525 c5f9681c77522f3279292ee13b93c468 396 Gene3D G3DSA:3.30.1540.10 239 304 8.2E-6 T 11-11-2016 AUP74_RS02525 c5f9681c77522f3279292ee13b93c468 396 Pfam PF02515 CoA-transferase family III 8 371 8.5E-95 T 11-11-2016 IPR003673 CoA-transferase family III GO:0003824 AUP74_RS02525 c5f9681c77522f3279292ee13b93c468 396 Gene3D G3DSA:3.40.50.10540 305 395 2.5E-108 T 11-11-2016 IPR023606 CoA-transferase family III domain AUP74_RS02525 c5f9681c77522f3279292ee13b93c468 396 Gene3D G3DSA:3.40.50.10540 4 221 2.5E-108 T 11-11-2016 IPR023606 CoA-transferase family III domain AUP74_RS02525 c5f9681c77522f3279292ee13b93c468 396 SUPERFAMILY SSF89796 3 395 7.19E-118 T 11-11-2016 IPR023606 CoA-transferase family III domain AUP74_RS05550 cc75797471d39b1fffe90920b0017052 419 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 419 249.025 T 11-11-2016 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 AUP74_RS05550 cc75797471d39b1fffe90920b0017052 419 SMART SM00959 5 47 8.4E-18 T 11-11-2016 IPR011112 Rho termination factor, N-terminal GO:0006353 AUP74_RS05550 cc75797471d39b1fffe90920b0017052 419 SUPERFAMILY SSF52540 90 371 2.55E-66 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05550 cc75797471d39b1fffe90920b0017052 419 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 160 363 9.8E-23 T 11-11-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AUP74_RS05550 cc75797471d39b1fffe90920b0017052 419 Gene3D G3DSA:2.40.50.140 49 116 2.5E-36 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS05550 cc75797471d39b1fffe90920b0017052 419 SMART SM00382 170 328 2.7E-5 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS05550 cc75797471d39b1fffe90920b0017052 419 SUPERFAMILY SSF50249 48 125 6.28E-29 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS05550 cc75797471d39b1fffe90920b0017052 419 TIGRFAM TIGR00767 rho: transcription termination factor Rho 2 417 3.9E-215 T 11-11-2016 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 AUP74_RS05550 cc75797471d39b1fffe90920b0017052 419 Pfam PF07498 Rho termination factor, N-terminal domain 5 47 5.7E-18 T 11-11-2016 IPR011112 Rho termination factor, N-terminal GO:0006353 AUP74_RS05550 cc75797471d39b1fffe90920b0017052 419 Gene3D G3DSA:3.40.50.300 132 418 8.2E-102 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05550 cc75797471d39b1fffe90920b0017052 419 Pfam PF07497 Rho termination factor, RNA-binding domain 52 125 5.7E-32 T 11-11-2016 IPR011113 Rho termination factor, RNA-binding GO:0003723|GO:0006353 AUP74_RS05550 cc75797471d39b1fffe90920b0017052 419 SUPERFAMILY SSF68912 1 46 9.42E-13 T 11-11-2016 IPR011112 Rho termination factor, N-terminal GO:0006353 AUP74_RS05550 cc75797471d39b1fffe90920b0017052 419 Gene3D G3DSA:1.10.720.10 1 47 6.9E-22 T 11-11-2016 AUP74_RS05550 cc75797471d39b1fffe90920b0017052 419 SMART SM00357 52 118 2.8E-18 T 11-11-2016 IPR011129 Cold shock protein GO:0003676 AUP74_RS16780 54339bb4c5b81286453c3145878481e2 147 Pfam PF02381 MraZ protein, putative antitoxin-like 79 131 4.9E-15 T 11-11-2016 IPR020603 MraZ domain AUP74_RS16780 54339bb4c5b81286453c3145878481e2 147 Pfam PF02381 MraZ protein, putative antitoxin-like 2 75 3.2E-15 T 11-11-2016 IPR020603 MraZ domain AUP74_RS16780 54339bb4c5b81286453c3145878481e2 147 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 3 142 8.0E-45 T 11-11-2016 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 AUP74_RS16780 54339bb4c5b81286453c3145878481e2 147 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 147 50.6 T 11-11-2016 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 AUP74_RS16780 54339bb4c5b81286453c3145878481e2 147 SUPERFAMILY SSF89447 2 135 1.5E-43 T 11-11-2016 AUP74_RS16780 54339bb4c5b81286453c3145878481e2 147 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 2 146 1.9E-42 T 11-11-2016 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 AUP74_RS02610 d72260a7ad7ef06f703da9136615eba4 495 SMART SM00220 11 265 6.5E-57 T 11-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AUP74_RS02610 d72260a7ad7ef06f703da9136615eba4 495 Gene3D G3DSA:3.30.200.20 7 118 8.8E-28 T 11-11-2016 AUP74_RS02610 d72260a7ad7ef06f703da9136615eba4 495 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 127 139 - T 11-11-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AUP74_RS02610 d72260a7ad7ef06f703da9136615eba4 495 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 11-11-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 AUP74_RS02610 d72260a7ad7ef06f703da9136615eba4 495 Pfam PF00069 Protein kinase domain 11 252 9.6E-50 T 11-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AUP74_RS02610 d72260a7ad7ef06f703da9136615eba4 495 SUPERFAMILY SSF48452 327 469 4.64E-7 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS02610 d72260a7ad7ef06f703da9136615eba4 495 Gene3D G3DSA:1.10.510.10 119 261 8.2E-41 T 11-11-2016 AUP74_RS02610 d72260a7ad7ef06f703da9136615eba4 495 Gene3D G3DSA:1.25.40.10 344 472 4.6E-7 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS02610 d72260a7ad7ef06f703da9136615eba4 495 SUPERFAMILY SSF56112 5 264 4.86E-69 T 11-11-2016 IPR011009 Protein kinase-like domain AUP74_RS01815 561889a5b5a47c23a3232e169fc541de 503 Pfam PF07690 Major Facilitator Superfamily 19 410 2.6E-60 T 11-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AUP74_RS01815 561889a5b5a47c23a3232e169fc541de 503 PRINTS PR01036 Tetracycline resistance protein TetB signature 109 129 7.4E-9 T 11-11-2016 AUP74_RS01815 561889a5b5a47c23a3232e169fc541de 503 PRINTS PR01036 Tetracycline resistance protein TetB signature 263 288 7.4E-9 T 11-11-2016 AUP74_RS01815 561889a5b5a47c23a3232e169fc541de 503 PRINTS PR01036 Tetracycline resistance protein TetB signature 18 42 7.4E-9 T 11-11-2016 AUP74_RS01815 561889a5b5a47c23a3232e169fc541de 503 PRINTS PR01036 Tetracycline resistance protein TetB signature 401 420 7.4E-9 T 11-11-2016 AUP74_RS01815 561889a5b5a47c23a3232e169fc541de 503 PRINTS PR01036 Tetracycline resistance protein TetB signature 205 223 7.4E-9 T 11-11-2016 AUP74_RS01815 561889a5b5a47c23a3232e169fc541de 503 PRINTS PR01036 Tetracycline resistance protein TetB signature 139 163 7.4E-9 T 11-11-2016 AUP74_RS01815 561889a5b5a47c23a3232e169fc541de 503 Gene3D G3DSA:1.20.1250.20 11 193 1.1E-33 T 11-11-2016 AUP74_RS01815 561889a5b5a47c23a3232e169fc541de 503 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 15 465 8.1E-121 T 11-11-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 AUP74_RS01815 561889a5b5a47c23a3232e169fc541de 503 SUPERFAMILY SSF103473 6 196 1.57E-71 T 11-11-2016 IPR020846 Major facilitator superfamily domain AUP74_RS01815 561889a5b5a47c23a3232e169fc541de 503 SUPERFAMILY SSF103473 249 420 1.57E-71 T 11-11-2016 IPR020846 Major facilitator superfamily domain AUP74_RS01815 561889a5b5a47c23a3232e169fc541de 503 SUPERFAMILY SSF103473 467 495 1.57E-71 T 11-11-2016 IPR020846 Major facilitator superfamily domain AUP74_RS01815 561889a5b5a47c23a3232e169fc541de 503 Gene3D G3DSA:1.20.1250.20 472 490 1.8E-17 T 11-11-2016 AUP74_RS01815 561889a5b5a47c23a3232e169fc541de 503 Gene3D G3DSA:1.20.1250.20 264 421 1.8E-17 T 11-11-2016 AUP74_RS14905 d9388324dfa0fd0b69f0193eac31c9ec 169 SUPERFAMILY SSF52540 2 167 1.3E-24 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS14905 d9388324dfa0fd0b69f0193eac31c9ec 169 Pfam PF01202 Shikimate kinase 13 166 3.5E-31 T 11-11-2016 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 AUP74_RS14905 d9388324dfa0fd0b69f0193eac31c9ec 169 Hamap MF_00109 Shikimate kinase [aroK]. 4 167 21.374 T 11-11-2016 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 AUP74_RS14905 d9388324dfa0fd0b69f0193eac31c9ec 169 PRINTS PR01100 Shikimate kinase family signature 7 22 1.9E-19 T 11-11-2016 AUP74_RS14905 d9388324dfa0fd0b69f0193eac31c9ec 169 PRINTS PR01100 Shikimate kinase family signature 76 85 1.9E-19 T 11-11-2016 AUP74_RS14905 d9388324dfa0fd0b69f0193eac31c9ec 169 PRINTS PR01100 Shikimate kinase family signature 97 114 1.9E-19 T 11-11-2016 AUP74_RS14905 d9388324dfa0fd0b69f0193eac31c9ec 169 PRINTS PR01100 Shikimate kinase family signature 59 67 1.9E-19 T 11-11-2016 AUP74_RS14905 d9388324dfa0fd0b69f0193eac31c9ec 169 PRINTS PR01100 Shikimate kinase family signature 31 44 1.9E-19 T 11-11-2016 AUP74_RS14905 d9388324dfa0fd0b69f0193eac31c9ec 169 Gene3D G3DSA:3.40.50.300 1 167 2.6E-44 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS14585 0f6fb5e8a20064ee4cbf0763355cbcc6 317 SUPERFAMILY SSF51569 3 288 7.77E-66 T 11-11-2016 AUP74_RS14585 0f6fb5e8a20064ee4cbf0763355cbcc6 317 Gene3D G3DSA:3.20.20.70 4 289 2.8E-68 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS14585 0f6fb5e8a20064ee4cbf0763355cbcc6 317 Pfam PF00682 HMGL-like 6 282 1.7E-47 T 11-11-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 AUP74_RS12955 ee9c18ea736d5d015c6ceaf809bd9734 323 Gene3D G3DSA:1.10.10.10 1 82 1.1E-21 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS12955 ee9c18ea736d5d015c6ceaf809bd9734 323 SUPERFAMILY SSF53850 90 319 6.63E-42 T 11-11-2016 AUP74_RS12955 ee9c18ea736d5d015c6ceaf809bd9734 323 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 64 4.5E-16 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS12955 ee9c18ea736d5d015c6ceaf809bd9734 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 9.1E-8 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS12955 ee9c18ea736d5d015c6ceaf809bd9734 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 9.1E-8 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS12955 ee9c18ea736d5d015c6ceaf809bd9734 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 9.1E-8 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS12955 ee9c18ea736d5d015c6ceaf809bd9734 323 SUPERFAMILY SSF46785 1 89 2.18E-15 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS12955 ee9c18ea736d5d015c6ceaf809bd9734 323 Pfam PF03466 LysR substrate binding domain 90 262 8.2E-41 T 11-11-2016 IPR005119 LysR, substrate-binding AUP74_RS12955 ee9c18ea736d5d015c6ceaf809bd9734 323 Gene3D G3DSA:3.40.190.10 91 183 8.7E-22 T 11-11-2016 AUP74_RS12955 ee9c18ea736d5d015c6ceaf809bd9734 323 Gene3D G3DSA:3.40.190.10 184 259 2.4E-27 T 11-11-2016 AUP74_RS06205 31d3405d58ca2323c3a3df027f5cdc8a 154 Gene3D G3DSA:3.10.590.10 2 150 3.5E-30 T 11-11-2016 IPR002740 EVE domain AUP74_RS06205 31d3405d58ca2323c3a3df027f5cdc8a 154 SUPERFAMILY SSF88697 2 152 2.65E-59 T 11-11-2016 IPR015947 PUA-like domain AUP74_RS06205 31d3405d58ca2323c3a3df027f5cdc8a 154 Pfam PF01878 EVE domain 2 149 4.8E-55 T 11-11-2016 IPR002740 EVE domain AUP74_RS12935 85ffbcf97eaa199d3eddcb68dd7f7b04 775 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 679 697 - T 11-11-2016 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 AUP74_RS12935 85ffbcf97eaa199d3eddcb68dd7f7b04 775 PIRSF PIRSF000854 1 775 0.0 T 11-11-2016 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 AUP74_RS12935 85ffbcf97eaa199d3eddcb68dd7f7b04 775 Gene3D G3DSA:3.20.20.60 466 772 3.0E-102 T 11-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AUP74_RS12935 85ffbcf97eaa199d3eddcb68dd7f7b04 775 Gene3D G3DSA:3.50.30.10 358 457 1.6E-35 T 11-11-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 AUP74_RS12935 85ffbcf97eaa199d3eddcb68dd7f7b04 775 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 399 410 - T 11-11-2016 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 AUP74_RS12935 85ffbcf97eaa199d3eddcb68dd7f7b04 775 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 2 773 0.0 T 11-11-2016 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 AUP74_RS12935 85ffbcf97eaa199d3eddcb68dd7f7b04 775 Pfam PF00391 PEP-utilising enzyme, mobile domain 369 440 1.4E-25 T 11-11-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 AUP74_RS12935 85ffbcf97eaa199d3eddcb68dd7f7b04 775 Gene3D G3DSA:3.30.470.20 181 341 1.5E-58 T 11-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 AUP74_RS12935 85ffbcf97eaa199d3eddcb68dd7f7b04 775 Gene3D G3DSA:3.30.1490.20 3 178 8.9E-64 T 11-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 AUP74_RS12935 85ffbcf97eaa199d3eddcb68dd7f7b04 775 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 5 328 4.0E-117 T 11-11-2016 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 AUP74_RS12935 85ffbcf97eaa199d3eddcb68dd7f7b04 775 SUPERFAMILY SSF52009 334 452 3.14E-34 T 11-11-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 AUP74_RS12935 85ffbcf97eaa199d3eddcb68dd7f7b04 775 SUPERFAMILY SSF51621 448 773 1.36E-95 T 11-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AUP74_RS12935 85ffbcf97eaa199d3eddcb68dd7f7b04 775 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 467 764 6.0E-58 T 11-11-2016 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 AUP74_RS12935 85ffbcf97eaa199d3eddcb68dd7f7b04 775 SUPERFAMILY SSF56059 2 367 1.29E-101 T 11-11-2016 AUP74_RS12935 85ffbcf97eaa199d3eddcb68dd7f7b04 775 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 696 711 2.4E-5 T 11-11-2016 AUP74_RS12935 85ffbcf97eaa199d3eddcb68dd7f7b04 775 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 679 694 2.4E-5 T 11-11-2016 AUP74_RS12935 85ffbcf97eaa199d3eddcb68dd7f7b04 775 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 732 744 2.4E-5 T 11-11-2016 AUP74_RS09275 7a17a4d33dda35ea6ebdde0176859b26 424 SUPERFAMILY SSF142019 17 239 1.83E-81 T 11-11-2016 AUP74_RS09275 7a17a4d33dda35ea6ebdde0176859b26 424 SMART SM00928 329 374 8.3E-22 T 11-11-2016 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09275 7a17a4d33dda35ea6ebdde0176859b26 424 SUPERFAMILY SSF142984 241 324 1.83E-22 T 11-11-2016 AUP74_RS09275 7a17a4d33dda35ea6ebdde0176859b26 424 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 342 353 - T 11-11-2016 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09275 7a17a4d33dda35ea6ebdde0176859b26 424 Pfam PF10531 SLBB domain 246 289 1.5E-9 T 11-11-2016 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09275 7a17a4d33dda35ea6ebdde0176859b26 424 SUPERFAMILY SSF140490 326 423 6.02E-32 T 11-11-2016 AUP74_RS09275 7a17a4d33dda35ea6ebdde0176859b26 424 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 332 415 9.3E-26 T 11-11-2016 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09275 7a17a4d33dda35ea6ebdde0176859b26 424 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 46 219 5.4E-51 T 11-11-2016 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS00540 c730e65fe478a71a528249f8a7f3b0d2 153 Gene3D G3DSA:1.10.3680.10 15 146 5.6E-19 T 11-11-2016 IPR029024 TerB-like AUP74_RS00540 c730e65fe478a71a528249f8a7f3b0d2 153 SUPERFAMILY SSF158682 18 147 2.75E-25 T 11-11-2016 IPR029024 TerB-like AUP74_RS00540 c730e65fe478a71a528249f8a7f3b0d2 153 Pfam PF05099 Tellurite resistance protein TerB 12 144 8.4E-36 T 11-11-2016 IPR007791 Co-chaperone DjlA, N-terminal AUP74_RS12915 6e657251a68fb83a2fb481bd943a9313 742 Gene3D G3DSA:3.40.810.20 488 623 5.6E-15 T 11-11-2016 AUP74_RS12915 6e657251a68fb83a2fb481bd943a9313 742 SUPERFAMILY SSF100950 306 334 2.15E-44 T 11-11-2016 AUP74_RS12915 6e657251a68fb83a2fb481bd943a9313 742 SUPERFAMILY SSF100950 427 629 2.15E-44 T 11-11-2016 AUP74_RS12915 6e657251a68fb83a2fb481bd943a9313 742 SUPERFAMILY SSF100950 232 273 2.15E-44 T 11-11-2016 AUP74_RS12915 6e657251a68fb83a2fb481bd943a9313 742 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 441 604 3.4E-45 T 11-11-2016 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain AUP74_RS12915 6e657251a68fb83a2fb481bd943a9313 742 Gene3D G3DSA:3.40.1080.10 132 222 1.0E-4 T 11-11-2016 AUP74_RS12915 6e657251a68fb83a2fb481bd943a9313 742 Gene3D G3DSA:3.30.750.70 311 341 1.4E-24 T 11-11-2016 AUP74_RS12915 6e657251a68fb83a2fb481bd943a9313 742 Gene3D G3DSA:3.30.750.70 432 457 1.4E-24 T 11-11-2016 AUP74_RS12915 6e657251a68fb83a2fb481bd943a9313 742 Gene3D G3DSA:3.30.750.70 231 276 1.4E-24 T 11-11-2016 AUP74_RS14465 2f3d9f2f3b8e2d64db28a65ec26caab8 490 Gene3D G3DSA:3.40.309.10 269 444 4.4E-47 T 11-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 AUP74_RS14465 2f3d9f2f3b8e2d64db28a65ec26caab8 490 SUPERFAMILY SSF53720 6 481 5.89E-116 T 11-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AUP74_RS14465 2f3d9f2f3b8e2d64db28a65ec26caab8 490 Pfam PF00171 Aldehyde dehydrogenase family 32 478 1.8E-113 T 11-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 AUP74_RS14465 2f3d9f2f3b8e2d64db28a65ec26caab8 490 Gene3D G3DSA:3.40.605.10 9 268 1.2E-60 T 11-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AUP74_RS09845 82f2150224c8eaa5e1d69210948af3bb 503 Gene3D G3DSA:3.40.1030.10 166 418 1.9E-65 T 11-11-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AUP74_RS09845 82f2150224c8eaa5e1d69210948af3bb 503 Hamap MF_00703 Putative thymidine phosphorylase. 8 501 51.937 T 11-11-2016 IPR028579 Putative thymidine phosphorylase KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181 AUP74_RS09845 82f2150224c8eaa5e1d69210948af3bb 503 Pfam PF00591 Glycosyl transferase family, a/b domain 170 241 2.0E-6 T 11-11-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AUP74_RS09845 82f2150224c8eaa5e1d69210948af3bb 503 SMART SM00941 430 497 9.1E-14 T 11-11-2016 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AUP74_RS09845 82f2150224c8eaa5e1d69210948af3bb 503 Pfam PF02885 Glycosyl transferase family, helical bundle domain 99 159 7.6E-12 T 11-11-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 AUP74_RS09845 82f2150224c8eaa5e1d69210948af3bb 503 Gene3D G3DSA:3.90.1170.30 419 493 1.6E-12 T 11-11-2016 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AUP74_RS09845 82f2150224c8eaa5e1d69210948af3bb 503 TIGRFAM TIGR02645 ARCH_P_rylase: putative thymidine phosphorylase 10 487 1.0E-160 T 11-11-2016 IPR013466 Thymidine phosphorylase/AMP phosphorylase GO:0016763 AUP74_RS09845 82f2150224c8eaa5e1d69210948af3bb 503 SUPERFAMILY SSF52418 164 417 9.42E-61 T 11-11-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AUP74_RS09845 82f2150224c8eaa5e1d69210948af3bb 503 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 203 218 - T 11-11-2016 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AUP74_RS09845 82f2150224c8eaa5e1d69210948af3bb 503 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 434 493 9.5E-8 T 11-11-2016 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AUP74_RS09845 82f2150224c8eaa5e1d69210948af3bb 503 SUPERFAMILY SSF47648 95 162 9.81E-13 T 11-11-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 AUP74_RS09845 82f2150224c8eaa5e1d69210948af3bb 503 Gene3D G3DSA:1.20.970.10 95 160 4.8E-13 T 11-11-2016 AUP74_RS09845 82f2150224c8eaa5e1d69210948af3bb 503 SUPERFAMILY SSF54680 417 497 1.44E-13 T 11-11-2016 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AUP74_RS06915 0203e5d64c64d07a4dff2f0ad8ebaab6 61 PIRSF PIRSF002211 1 61 8.6E-28 T 11-11-2016 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 AUP74_RS06915 0203e5d64c64d07a4dff2f0ad8ebaab6 61 SUPERFAMILY SSF55129 4 59 2.22E-21 T 11-11-2016 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain AUP74_RS06915 0203e5d64c64d07a4dff2f0ad8ebaab6 61 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 6 59 3.8E-24 T 11-11-2016 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 AUP74_RS06915 0203e5d64c64d07a4dff2f0ad8ebaab6 61 Gene3D G3DSA:3.30.1390.20 3 59 9.1E-30 T 11-11-2016 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain AUP74_RS06915 0203e5d64c64d07a4dff2f0ad8ebaab6 61 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 2 60 21.082 T 11-11-2016 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 AUP74_RS06915 0203e5d64c64d07a4dff2f0ad8ebaab6 61 Pfam PF00327 Ribosomal protein L30p/L7e 6 56 7.6E-21 T 11-11-2016 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain AUP74_RS09285 7757353649f37706d395ab15f785eee4 573 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 226 237 - T 11-11-2016 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09285 7757353649f37706d395ab15f785eee4 573 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 189 573 5.5E-162 T 11-11-2016 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09285 7757353649f37706d395ab15f785eee4 573 Gene3D G3DSA:1.10.645.10 192 565 2.1E-56 T 11-11-2016 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09285 7757353649f37706d395ab15f785eee4 573 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 79 134 1.0E-16 T 11-11-2016 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09285 7757353649f37706d395ab15f785eee4 573 SUPERFAMILY SSF143243 12 203 1.57E-56 T 11-11-2016 AUP74_RS09285 7757353649f37706d395ab15f785eee4 573 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 1 159 25.992 T 11-11-2016 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09285 7757353649f37706d395ab15f785eee4 573 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 183 573 44.015 T 11-11-2016 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09285 7757353649f37706d395ab15f785eee4 573 Hamap MF_01359 NADH-quinone oxidoreductase subunit C/D [nuoC]. 3 573 66.55 T 11-11-2016 IPR023062 NADH dehydrogenase, subunit CD GO:0030964|GO:0050136|GO:0055114 KEGG: 00190+1.6.5.11 AUP74_RS09285 7757353649f37706d395ab15f785eee4 573 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 19 149 1.2E-37 T 11-11-2016 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09285 7757353649f37706d395ab15f785eee4 573 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 20 151 8.3E-40 T 11-11-2016 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09285 7757353649f37706d395ab15f785eee4 573 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 112 133 - T 11-11-2016 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09285 7757353649f37706d395ab15f785eee4 573 SUPERFAMILY SSF56762 199 573 6.28E-130 T 11-11-2016 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09285 7757353649f37706d395ab15f785eee4 573 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 303 573 4.2E-110 T 11-11-2016 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS11710 49401975c4f5bd911bf6af0a3bbcddb8 389 Gene3D G3DSA:3.40.50.720 286 389 3.5E-48 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS11710 49401975c4f5bd911bf6af0a3bbcddb8 389 SUPERFAMILY SSF48179 192 288 9.52E-31 T 11-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AUP74_RS11710 49401975c4f5bd911bf6af0a3bbcddb8 389 Gene3D G3DSA:3.40.50.720 2 198 5.2E-68 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS11710 49401975c4f5bd911bf6af0a3bbcddb8 389 SMART SM00984 301 388 3.1E-13 T 11-11-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AUP74_RS11710 49401975c4f5bd911bf6af0a3bbcddb8 389 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 302 376 1.2E-8 T 11-11-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AUP74_RS11710 49401975c4f5bd911bf6af0a3bbcddb8 389 Gene3D G3DSA:1.10.1040.10 199 285 4.0E-34 T 11-11-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AUP74_RS11710 49401975c4f5bd911bf6af0a3bbcddb8 389 SUPERFAMILY SSF52413 284 388 4.97E-27 T 11-11-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AUP74_RS11710 49401975c4f5bd911bf6af0a3bbcddb8 389 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 3 378 5.1E-104 T 11-11-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AUP74_RS11710 49401975c4f5bd911bf6af0a3bbcddb8 389 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 193 282 1.7E-26 T 11-11-2016 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AUP74_RS11710 49401975c4f5bd911bf6af0a3bbcddb8 389 PIRSF PIRSF500134 2 348 9.5E-121 T 11-11-2016 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00500+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346 AUP74_RS11710 49401975c4f5bd911bf6af0a3bbcddb8 389 SUPERFAMILY SSF51735 2 195 1.07E-48 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS11710 49401975c4f5bd911bf6af0a3bbcddb8 389 PIRSF PIRSF000124 2 389 2.9E-135 T 11-11-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AUP74_RS11710 49401975c4f5bd911bf6af0a3bbcddb8 389 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3 170 1.5E-31 T 11-11-2016 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AUP74_RS10570 16d31031e1150d088d91e5f9278fe631 146 SUPERFAMILY SSF51316 5 135 1.15E-57 T 11-11-2016 IPR011057 Mss4-like AUP74_RS10570 16d31031e1150d088d91e5f9278fe631 146 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 5 132 2.0E-52 T 11-11-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 AUP74_RS10570 16d31031e1150d088d91e5f9278fe631 146 Pfam PF01641 SelR domain 10 126 8.0E-52 T 11-11-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 AUP74_RS10570 16d31031e1150d088d91e5f9278fe631 146 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 2 129 35.771 T 11-11-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 AUP74_RS10570 16d31031e1150d088d91e5f9278fe631 146 Gene3D G3DSA:2.170.150.20 3 135 1.8E-60 T 11-11-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 AUP74_RS06865 50409e80749e5c1367004e2c1f7883c4 63 Pfam PF00831 Ribosomal L29 protein 5 60 1.8E-22 T 11-11-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06865 50409e80749e5c1367004e2c1f7883c4 63 SUPERFAMILY SSF46561 1 61 3.66E-21 T 11-11-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06865 50409e80749e5c1367004e2c1f7883c4 63 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 1.2E-22 T 11-11-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06865 50409e80749e5c1367004e2c1f7883c4 63 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 18.357 T 11-11-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06865 50409e80749e5c1367004e2c1f7883c4 63 Gene3D G3DSA:1.10.287.310 1 60 5.9E-26 T 11-11-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06865 50409e80749e5c1367004e2c1f7883c4 63 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 11-11-2016 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS13875 cb00fa0ad8745fb45fdaf46243d09fd3 99 Pfam PF07130 YebG protein 1 71 1.1E-21 T 11-11-2016 IPR009813 Uncharacterised protein family YebG AUP74_RS13875 cb00fa0ad8745fb45fdaf46243d09fd3 99 Gene3D G3DSA:1.10.10.710 18 85 3.4E-22 T 11-11-2016 IPR009813 Uncharacterised protein family YebG AUP74_RS16800 47ae7963d9011d003e2f1bde00339e97 639 SUPERFAMILY SSF53822 465 616 3.24E-73 T 11-11-2016 IPR028082 Periplasmic binding protein-like I AUP74_RS16800 47ae7963d9011d003e2f1bde00339e97 639 SUPERFAMILY SSF53822 271 437 3.24E-73 T 11-11-2016 IPR028082 Periplasmic binding protein-like I AUP74_RS16800 47ae7963d9011d003e2f1bde00339e97 639 Gene3D G3DSA:3.40.50.2300 380 540 1.4E-43 T 11-11-2016 AUP74_RS16800 47ae7963d9011d003e2f1bde00339e97 639 Pfam PF04348 LppC putative lipoprotein 47 610 8.3E-114 T 11-11-2016 IPR007443 Penicillin-binding protein activator LpoA AUP74_RS16800 47ae7963d9011d003e2f1bde00339e97 639 Gene3D G3DSA:3.40.50.2300 541 602 3.3E-49 T 11-11-2016 AUP74_RS16800 47ae7963d9011d003e2f1bde00339e97 639 Gene3D G3DSA:3.40.50.2300 270 377 3.3E-49 T 11-11-2016 AUP74_RS08290 824d5ac2078844fa84560ce6a3a59498 235 Pfam PF03749 Sugar fermentation stimulation protein 13 224 2.8E-72 T 11-11-2016 IPR005224 Sugar fermentation stimulation protein AUP74_RS08290 824d5ac2078844fa84560ce6a3a59498 235 Hamap MF_00095 Sugar fermentation stimulation protein A [sfsA]. 1 233 54.252 T 11-11-2016 IPR005224 Sugar fermentation stimulation protein AUP74_RS08290 824d5ac2078844fa84560ce6a3a59498 235 TIGRFAM TIGR00230 sfsA: sugar fermentation stimulation protein 5 223 1.2E-66 T 11-11-2016 IPR005224 Sugar fermentation stimulation protein AUP74_RS14745 0f8f2850f870e1ac420898800232da2c 670 Gene3D G3DSA:4.10.860.10 630 667 3.6E-15 T 11-11-2016 IPR001943 UVR domain GO:0005515 AUP74_RS14745 0f8f2850f870e1ac420898800232da2c 670 Gene3D G3DSA:3.40.50.300 389 410 3.4E-54 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS14745 0f8f2850f870e1ac420898800232da2c 670 Gene3D G3DSA:3.40.50.300 7 90 3.4E-54 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS14745 0f8f2850f870e1ac420898800232da2c 670 Gene3D G3DSA:3.40.50.300 279 339 3.4E-54 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS14745 0f8f2850f870e1ac420898800232da2c 670 SMART SM00490 460 546 3.7E-19 T 11-11-2016 IPR001650 Helicase, C-terminal AUP74_RS14745 0f8f2850f870e1ac420898800232da2c 670 Gene3D G3DSA:3.30.2060.10 161 231 2.3E-7 T 11-11-2016 AUP74_RS14745 0f8f2850f870e1ac420898800232da2c 670 Gene3D G3DSA:3.40.50.300 419 581 1.1E-40 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS14745 0f8f2850f870e1ac420898800232da2c 670 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 6 666 0.0 T 11-11-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 AUP74_RS14745 0f8f2850f870e1ac420898800232da2c 670 SUPERFAMILY SSF52540 38 83 8.57E-36 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS14745 0f8f2850f870e1ac420898800232da2c 670 SUPERFAMILY SSF52540 459 582 8.57E-36 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS14745 0f8f2850f870e1ac420898800232da2c 670 Pfam PF12344 Ultra-violet resistance protein B 552 593 1.6E-21 T 11-11-2016 IPR024759 UvrB, YAD/RRR-motif-containing domain AUP74_RS14745 0f8f2850f870e1ac420898800232da2c 670 Hamap MF_00204 UvrABC system protein B [uvrB]. 4 668 43.475 T 11-11-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 AUP74_RS14745 0f8f2850f870e1ac420898800232da2c 670 SMART SM00487 10 425 1.4E-27 T 11-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain AUP74_RS14745 0f8f2850f870e1ac420898800232da2c 670 SUPERFAMILY SSF46600 628 667 1.7E-10 T 11-11-2016 IPR001943 UVR domain GO:0005515 AUP74_RS14745 0f8f2850f870e1ac420898800232da2c 670 SUPERFAMILY SSF52540 5 415 1.19E-139 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS14745 0f8f2850f870e1ac420898800232da2c 670 Pfam PF04851 Type III restriction enzyme, res subunit 14 120 3.1E-9 T 11-11-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 AUP74_RS14745 0f8f2850f870e1ac420898800232da2c 670 Pfam PF02151 UvrB/uvrC motif 635 667 6.3E-10 T 11-11-2016 IPR001943 UVR domain GO:0005515 AUP74_RS14745 0f8f2850f870e1ac420898800232da2c 670 Pfam PF00271 Helicase conserved C-terminal domain 436 545 3.1E-19 T 11-11-2016 IPR001650 Helicase, C-terminal AUP74_RS09580 e4667d421d78c15068c32d7585bde991 97 SMART SM00883 2 95 1.5E-53 T 11-11-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AUP74_RS09580 e4667d421d78c15068c32d7585bde991 97 Hamap MF_00580 10 kDa chaperonin [groS]. 2 96 26.482 T 11-11-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AUP74_RS09580 e4667d421d78c15068c32d7585bde991 97 Pfam PF00166 Chaperonin 10 Kd subunit 2 94 6.0E-32 T 11-11-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AUP74_RS09580 e4667d421d78c15068c32d7585bde991 97 SUPERFAMILY SSF50129 1 96 8.67E-34 T 11-11-2016 IPR011032 GroES-like AUP74_RS09580 e4667d421d78c15068c32d7585bde991 97 PRINTS PR00297 10kDa chaperonin signature 25 46 1.5E-30 T 11-11-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AUP74_RS09580 e4667d421d78c15068c32d7585bde991 97 PRINTS PR00297 10kDa chaperonin signature 3 18 1.5E-30 T 11-11-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AUP74_RS09580 e4667d421d78c15068c32d7585bde991 97 PRINTS PR00297 10kDa chaperonin signature 60 72 1.5E-30 T 11-11-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AUP74_RS09580 e4667d421d78c15068c32d7585bde991 97 PRINTS PR00297 10kDa chaperonin signature 82 95 1.5E-30 T 11-11-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AUP74_RS09580 e4667d421d78c15068c32d7585bde991 97 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 11-11-2016 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 AUP74_RS09580 e4667d421d78c15068c32d7585bde991 97 Gene3D G3DSA:2.30.33.40 1 96 2.5E-35 T 11-11-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AUP74_RS00175 47c0b78855d9d0179992237438af6d5f 186 Pfam PF03550 Outer membrane lipoprotein LolB 28 184 4.0E-44 T 11-11-2016 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 AUP74_RS00175 47c0b78855d9d0179992237438af6d5f 186 SUPERFAMILY SSF89392 7 185 1.22E-42 T 11-11-2016 IPR029046 Lipoprotein localisation LolA/LolB/LppX AUP74_RS00175 47c0b78855d9d0179992237438af6d5f 186 TIGRFAM TIGR00548 lolB: outer membrane lipoprotein LolB 2 185 3.5E-36 T 11-11-2016 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 AUP74_RS00175 47c0b78855d9d0179992237438af6d5f 186 Gene3D G3DSA:2.50.20.10 2 184 1.3E-53 T 11-11-2016 AUP74_RS05100 d82a8916d961d7841feada9f77798549 473 Gene3D G3DSA:3.40.720.10 14 373 2.2E-86 T 11-11-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 AUP74_RS05100 d82a8916d961d7841feada9f77798549 473 Gene3D G3DSA:3.30.1120.10 374 437 2.6E-4 T 11-11-2016 AUP74_RS05100 d82a8916d961d7841feada9f77798549 473 SUPERFAMILY SSF53649 4 419 3.63E-102 T 11-11-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 AUP74_RS05100 d82a8916d961d7841feada9f77798549 473 Pfam PF00884 Sulfatase 15 321 6.9E-60 T 11-11-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 AUP74_RS15650 aaf5f8c4f59a80b7c61ce4b4e0604399 287 Pfam PF00889 Elongation factor TS 72 266 2.1E-65 T 11-11-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AUP74_RS15650 aaf5f8c4f59a80b7c61ce4b4e0604399 287 SUPERFAMILY SSF46934 1 55 1.05E-17 T 11-11-2016 IPR009060 UBA-like GO:0005515 AUP74_RS15650 aaf5f8c4f59a80b7c61ce4b4e0604399 287 Gene3D G3DSA:3.30.479.20 231 269 2.5E-29 T 11-11-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AUP74_RS15650 aaf5f8c4f59a80b7c61ce4b4e0604399 287 Gene3D G3DSA:3.30.479.20 170 185 2.5E-29 T 11-11-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AUP74_RS15650 aaf5f8c4f59a80b7c61ce4b4e0604399 287 Gene3D G3DSA:3.30.479.20 56 94 2.5E-29 T 11-11-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AUP74_RS15650 aaf5f8c4f59a80b7c61ce4b4e0604399 287 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 284 1.3E-98 T 11-11-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AUP74_RS15650 aaf5f8c4f59a80b7c61ce4b4e0604399 287 Gene3D G3DSA:1.10.286.20 186 230 2.2E-18 T 11-11-2016 AUP74_RS15650 aaf5f8c4f59a80b7c61ce4b4e0604399 287 Gene3D G3DSA:1.10.8.10 1 54 4.0E-25 T 11-11-2016 AUP74_RS15650 aaf5f8c4f59a80b7c61ce4b4e0604399 287 SUPERFAMILY SSF54713 144 285 2.35E-52 T 11-11-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AUP74_RS15650 aaf5f8c4f59a80b7c61ce4b4e0604399 287 SUPERFAMILY SSF54713 56 141 9.37E-17 T 11-11-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AUP74_RS15650 aaf5f8c4f59a80b7c61ce4b4e0604399 287 Hamap MF_00050 Elongation factor Ts [tsf]. 1 283 74.578 T 11-11-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AUP74_RS15650 aaf5f8c4f59a80b7c61ce4b4e0604399 287 ProSitePatterns PS01127 Elongation factor Ts signature 2. 76 86 - T 11-11-2016 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AUP74_RS06825 679b0b7016ec90c2dc6037ce5f2ad303 211 Gene3D G3DSA:2.40.30.10 4 33 1.1E-10 T 11-11-2016 AUP74_RS06825 679b0b7016ec90c2dc6037ce5f2ad303 211 Gene3D G3DSA:2.40.30.10 160 209 1.1E-10 T 11-11-2016 AUP74_RS06825 679b0b7016ec90c2dc6037ce5f2ad303 211 SUPERFAMILY SSF50447 1 210 4.24E-85 T 11-11-2016 IPR009000 Translation protein, beta-barrel domain AUP74_RS06825 679b0b7016ec90c2dc6037ce5f2ad303 211 Gene3D G3DSA:4.10.960.10 89 159 4.3E-34 T 11-11-2016 AUP74_RS06825 679b0b7016ec90c2dc6037ce5f2ad303 211 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 206 3.1E-93 T 11-11-2016 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06825 679b0b7016ec90c2dc6037ce5f2ad303 211 Pfam PF00297 Ribosomal protein L3 85 184 9.5E-19 T 11-11-2016 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS06825 679b0b7016ec90c2dc6037ce5f2ad303 211 ProSitePatterns PS00474 Ribosomal protein L3 signature. 103 126 - T 11-11-2016 IPR019926 Ribosomal protein L3, conserved site AUP74_RS06825 679b0b7016ec90c2dc6037ce5f2ad303 211 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 209 40.613 T 11-11-2016 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS05665 06401252671b829b276348bd97e201eb 305 PIRSF PIRSF001438 1 305 3.9E-117 T 11-11-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AUP74_RS05665 06401252671b829b276348bd97e201eb 305 SUPERFAMILY SSF53850 5 210 1.97E-81 T 11-11-2016 AUP74_RS05665 06401252671b829b276348bd97e201eb 305 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 230 246 - T 11-11-2016 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AUP74_RS05665 06401252671b829b276348bd97e201eb 305 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 5 296 39.125 T 11-11-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AUP74_RS05665 06401252671b829b276348bd97e201eb 305 Gene3D G3DSA:3.30.160.40 220 304 1.0E-26 T 11-11-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AUP74_RS05665 06401252671b829b276348bd97e201eb 305 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 6 296 7.9E-107 T 11-11-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AUP74_RS05665 06401252671b829b276348bd97e201eb 305 SUPERFAMILY SSF54782 219 304 3.79E-27 T 11-11-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AUP74_RS05665 06401252671b829b276348bd97e201eb 305 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 6 208 3.2E-74 T 11-11-2016 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AUP74_RS05665 06401252671b829b276348bd97e201eb 305 PRINTS PR00151 Porphobilinogen deaminase signature 76 95 6.5E-50 T 11-11-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AUP74_RS05665 06401252671b829b276348bd97e201eb 305 PRINTS PR00151 Porphobilinogen deaminase signature 45 65 6.5E-50 T 11-11-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AUP74_RS05665 06401252671b829b276348bd97e201eb 305 PRINTS PR00151 Porphobilinogen deaminase signature 124 141 6.5E-50 T 11-11-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AUP74_RS05665 06401252671b829b276348bd97e201eb 305 PRINTS PR00151 Porphobilinogen deaminase signature 143 160 6.5E-50 T 11-11-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AUP74_RS05665 06401252671b829b276348bd97e201eb 305 PRINTS PR00151 Porphobilinogen deaminase signature 229 246 6.5E-50 T 11-11-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AUP74_RS05665 06401252671b829b276348bd97e201eb 305 Gene3D G3DSA:3.40.190.10 110 199 9.0E-39 T 11-11-2016 AUP74_RS05665 06401252671b829b276348bd97e201eb 305 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 226 294 2.3E-20 T 11-11-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AUP74_RS05665 06401252671b829b276348bd97e201eb 305 Gene3D G3DSA:3.40.190.10 5 109 1.0E-45 T 11-11-2016 AUP74_RS01670 10ab7d015f6964f86b8179fd00eec478 205 SUPERFAMILY SSF53335 22 203 1.15E-33 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS01670 10ab7d015f6964f86b8179fd00eec478 205 Pfam PF08241 Methyltransferase domain 38 134 1.4E-18 T 11-11-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 AUP74_RS01670 10ab7d015f6964f86b8179fd00eec478 205 Gene3D G3DSA:3.40.50.150 31 185 6.3E-28 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS03205 f3e57983e1a5807b83df42be014f7950 517 Pfam PF01676 Metalloenzyme superfamily 12 501 1.6E-75 T 11-11-2016 IPR006124 Metalloenzyme GO:0003824|GO:0046872 AUP74_RS03205 f3e57983e1a5807b83df42be014f7950 517 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 89 301 9.9E-79 T 11-11-2016 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AUP74_RS03205 f3e57983e1a5807b83df42be014f7950 517 SUPERFAMILY SSF53649 313 513 1.44E-69 T 11-11-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 AUP74_RS03205 f3e57983e1a5807b83df42be014f7950 517 SUPERFAMILY SSF53649 11 84 1.44E-69 T 11-11-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 AUP74_RS03205 f3e57983e1a5807b83df42be014f7950 517 SUPERFAMILY SSF64158 84 312 1.28E-83 T 11-11-2016 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AUP74_RS03205 f3e57983e1a5807b83df42be014f7950 517 Gene3D G3DSA:3.40.1450.10 85 313 1.9E-92 T 11-11-2016 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AUP74_RS03205 f3e57983e1a5807b83df42be014f7950 517 PIRSF PIRSF001492 5 516 1.5E-200 T 11-11-2016 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AUP74_RS03205 f3e57983e1a5807b83df42be014f7950 517 Gene3D G3DSA:3.40.720.10 12 84 7.0E-80 T 11-11-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 AUP74_RS03205 f3e57983e1a5807b83df42be014f7950 517 Gene3D G3DSA:3.40.720.10 317 513 7.0E-80 T 11-11-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 AUP74_RS03205 f3e57983e1a5807b83df42be014f7950 517 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 12 513 5.6E-222 T 11-11-2016 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AUP74_RS03205 f3e57983e1a5807b83df42be014f7950 517 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 11 514 50.065 T 11-11-2016 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AUP74_RS14940 4d742b4bfa89c0f9fd04609054cdc63e 461 Gene3D G3DSA:3.10.20.70 18 126 2.4E-7 T 11-11-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AUP74_RS14940 4d742b4bfa89c0f9fd04609054cdc63e 461 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 260 275 - T 11-11-2016 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 AUP74_RS14940 4d742b4bfa89c0f9fd04609054cdc63e 461 Gene3D G3DSA:3.30.590.10 127 446 2.2E-94 T 11-11-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 AUP74_RS14940 4d742b4bfa89c0f9fd04609054cdc63e 461 SUPERFAMILY SSF54368 19 123 4.58E-11 T 11-11-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AUP74_RS14940 4d742b4bfa89c0f9fd04609054cdc63e 461 SMART SM01230 123 379 1.3E-101 T 11-11-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AUP74_RS14940 4d742b4bfa89c0f9fd04609054cdc63e 461 SUPERFAMILY SSF55931 125 459 2.26E-103 T 11-11-2016 AUP74_RS14940 4d742b4bfa89c0f9fd04609054cdc63e 461 Pfam PF00120 Glutamine synthetase, catalytic domain 124 457 1.4E-103 T 11-11-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AUP74_RS03520 2fa5303adf0fe6b8c627e88715f012bf 292 SUPERFAMILY SSF118352 228 285 2.09E-17 T 11-11-2016 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 AUP74_RS03520 2fa5303adf0fe6b8c627e88715f012bf 292 PIRSF PIRSF005261 1 287 6.4E-76 T 11-11-2016 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 AUP74_RS03520 2fa5303adf0fe6b8c627e88715f012bf 292 Gene3D G3DSA:3.90.1280.10 227 285 3.6E-22 T 11-11-2016 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 AUP74_RS03520 2fa5303adf0fe6b8c627e88715f012bf 292 Pfam PF01430 Hsp33 protein 3 276 3.9E-81 T 11-11-2016 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 AUP74_RS03520 2fa5303adf0fe6b8c627e88715f012bf 292 SUPERFAMILY SSF64397 2 236 4.32E-64 T 11-11-2016 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 AUP74_RS03520 2fa5303adf0fe6b8c627e88715f012bf 292 Gene3D G3DSA:1.10.287.480 181 217 3.7E-11 T 11-11-2016 IPR023212 Heat shock protein Hsp33, helix hairpin bin domain AUP74_RS03520 2fa5303adf0fe6b8c627e88715f012bf 292 Hamap MF_00117 33 kDa chaperonin [hslO]. 2 287 29.729 T 11-11-2016 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 AUP74_RS03520 2fa5303adf0fe6b8c627e88715f012bf 292 Gene3D G3DSA:3.55.30.10 1 173 1.2E-57 T 11-11-2016 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 AUP74_RS03570 3791f5b17daa7a00dabb9dd6ac69ab28 366 SUPERFAMILY SSF47384 133 198 2.16E-14 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS03570 3791f5b17daa7a00dabb9dd6ac69ab28 366 SUPERFAMILY SSF55874 208 363 1.96E-32 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS03570 3791f5b17daa7a00dabb9dd6ac69ab28 366 SUPERFAMILY SSF55785 17 111 1.56E-10 T 11-11-2016 IPR000014 PAS domain AUP74_RS03570 3791f5b17daa7a00dabb9dd6ac69ab28 366 Pfam PF00512 His Kinase A (phospho-acceptor) domain 143 198 2.9E-16 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS03570 3791f5b17daa7a00dabb9dd6ac69ab28 366 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 246 364 1.0E-13 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS03570 3791f5b17daa7a00dabb9dd6ac69ab28 366 PRINTS PR00344 Bacterial sensor protein C-terminal signature 297 311 1.6E-11 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS03570 3791f5b17daa7a00dabb9dd6ac69ab28 366 PRINTS PR00344 Bacterial sensor protein C-terminal signature 315 325 1.6E-11 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS03570 3791f5b17daa7a00dabb9dd6ac69ab28 366 PRINTS PR00344 Bacterial sensor protein C-terminal signature 349 362 1.6E-11 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS03570 3791f5b17daa7a00dabb9dd6ac69ab28 366 PRINTS PR00344 Bacterial sensor protein C-terminal signature 326 344 1.6E-11 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS03570 3791f5b17daa7a00dabb9dd6ac69ab28 366 SMART SM00388 141 206 8.1E-14 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS03570 3791f5b17daa7a00dabb9dd6ac69ab28 366 SMART SM00387 245 365 1.3E-26 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS03570 3791f5b17daa7a00dabb9dd6ac69ab28 366 Gene3D G3DSA:3.30.450.20 17 112 6.3E-19 T 11-11-2016 AUP74_RS03570 3791f5b17daa7a00dabb9dd6ac69ab28 366 Pfam PF08448 PAS fold 23 111 2.6E-8 T 11-11-2016 IPR013656 PAS fold-4 AUP74_RS03570 3791f5b17daa7a00dabb9dd6ac69ab28 366 Gene3D G3DSA:3.30.565.10 205 364 1.6E-35 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS03570 3791f5b17daa7a00dabb9dd6ac69ab28 366 SMART SM00091 17 85 1.1E-5 T 11-11-2016 IPR000014 PAS domain AUP74_RS03570 3791f5b17daa7a00dabb9dd6ac69ab28 366 Gene3D G3DSA:1.10.287.130 136 198 1.9E-13 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS00615 1b3c3f66e49a2a34557d3f87c35a3477 377 Gene3D G3DSA:3.30.420.10 8 186 2.9E-14 T 11-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 AUP74_RS00615 1b3c3f66e49a2a34557d3f87c35a3477 377 SUPERFAMILY SSF53098 5 215 1.52E-65 T 11-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 AUP74_RS00615 1b3c3f66e49a2a34557d3f87c35a3477 377 SMART SM00474 8 176 1.1E-41 T 11-11-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 AUP74_RS00615 1b3c3f66e49a2a34557d3f87c35a3477 377 Pfam PF00570 HRDC domain 218 284 4.7E-12 T 11-11-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 AUP74_RS00615 1b3c3f66e49a2a34557d3f87c35a3477 377 SUPERFAMILY SSF47819 199 291 6.76E-23 T 11-11-2016 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 AUP74_RS00615 1b3c3f66e49a2a34557d3f87c35a3477 377 Hamap MF_01899 Ribonuclease D [rnd]. 8 368 38.974 T 11-11-2016 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 AUP74_RS00615 1b3c3f66e49a2a34557d3f87c35a3477 377 SMART SM00341 215 294 0.0017 T 11-11-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 AUP74_RS00615 1b3c3f66e49a2a34557d3f87c35a3477 377 TIGRFAM TIGR01388 rnd: ribonuclease D 10 364 7.7E-114 T 11-11-2016 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 AUP74_RS00615 1b3c3f66e49a2a34557d3f87c35a3477 377 Pfam PF01612 3'-5' exonuclease 9 175 3.9E-38 T 11-11-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 AUP74_RS00615 1b3c3f66e49a2a34557d3f87c35a3477 377 SUPERFAMILY SSF47819 297 368 1.51E-11 T 11-11-2016 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 AUP74_RS16075 5b94ba162b3873d7f9b6eaa2dcdf3b28 271 SUPERFAMILY SSF51366 7 250 6.4E-82 T 11-11-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 AUP74_RS16075 5b94ba162b3873d7f9b6eaa2dcdf3b28 271 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 19 268 32.686 T 11-11-2016 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AUP74_RS16075 5b94ba162b3873d7f9b6eaa2dcdf3b28 271 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 13 264 3.2E-68 T 11-11-2016 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AUP74_RS16075 5b94ba162b3873d7f9b6eaa2dcdf3b28 271 Pfam PF00290 Tryptophan synthase alpha chain 13 260 1.1E-79 T 11-11-2016 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AUP74_RS16075 5b94ba162b3873d7f9b6eaa2dcdf3b28 271 Gene3D G3DSA:3.20.20.70 7 270 2.6E-93 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS16075 5b94ba162b3873d7f9b6eaa2dcdf3b28 271 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 53 66 - T 11-11-2016 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AUP74_RS12710 b49a3dc12190edf64c86e6467f9a309c 89 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 24 78 3.7E-14 T 11-11-2016 IPR005953 ATPase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 AUP74_RS12710 b49a3dc12190edf64c86e6467f9a309c 89 Hamap MF_01396 ATP synthase subunit c [atpH]. 11 79 15.059 T 11-11-2016 AUP74_RS12710 b49a3dc12190edf64c86e6467f9a309c 89 Pfam PF00137 ATP synthase subunit C 15 76 2.4E-14 T 11-11-2016 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 AUP74_RS12710 b49a3dc12190edf64c86e6467f9a309c 89 Gene3D G3DSA:1.20.20.10 14 78 4.7E-22 T 11-11-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 AUP74_RS12710 b49a3dc12190edf64c86e6467f9a309c 89 SUPERFAMILY SSF81333 9 81 1.57E-18 T 11-11-2016 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 AUP74_RS12710 b49a3dc12190edf64c86e6467f9a309c 89 ProSitePatterns PS00605 ATP synthase c subunit signature. 42 63 - T 11-11-2016 IPR020537 ATPase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210 AUP74_RS12710 b49a3dc12190edf64c86e6467f9a309c 89 PRINTS PR00124 ATP synthase C subunit signature 35 50 1.4E-15 T 11-11-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 AUP74_RS12710 b49a3dc12190edf64c86e6467f9a309c 89 PRINTS PR00124 ATP synthase C subunit signature 52 77 1.4E-15 T 11-11-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 AUP74_RS12710 b49a3dc12190edf64c86e6467f9a309c 89 PRINTS PR00124 ATP synthase C subunit signature 14 33 1.4E-15 T 11-11-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 AUP74_RS07785 f14b418d29c08996ecf3bfe74ca28cf5 313 Gene3D G3DSA:3.40.50.720 15 112 4.8E-29 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS07785 f14b418d29c08996ecf3bfe74ca28cf5 313 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 223 239 - T 11-11-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site AUP74_RS07785 f14b418d29c08996ecf3bfe74ca28cf5 313 Gene3D G3DSA:3.40.50.720 113 288 1.2E-58 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS07785 f14b418d29c08996ecf3bfe74ca28cf5 313 SUPERFAMILY SSF51735 102 287 2.06E-51 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS07785 f14b418d29c08996ecf3bfe74ca28cf5 313 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 108 286 1.8E-54 T 11-11-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 AUP74_RS07785 f14b418d29c08996ecf3bfe74ca28cf5 313 SUPERFAMILY SSF52283 21 137 4.16E-30 T 11-11-2016 AUP74_RS07785 f14b418d29c08996ecf3bfe74ca28cf5 313 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 24 310 1.2E-22 T 11-11-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 AUP74_RS00070 bf0028ffc89ffd50e0e01f3dcd7017f2 495 Gene3D G3DSA:2.40.50.140 30 124 2.4E-32 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS00070 bf0028ffc89ffd50e0e01f3dcd7017f2 495 Pfam PF10150 Ribonuclease E/G family 122 399 1.4E-100 T 11-11-2016 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 AUP74_RS00070 bf0028ffc89ffd50e0e01f3dcd7017f2 495 SUPERFAMILY SSF50249 39 123 1.62E-18 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS00070 bf0028ffc89ffd50e0e01f3dcd7017f2 495 Pfam PF00575 S1 RNA binding domain 38 76 8.6E-6 T 11-11-2016 IPR003029 S1 domain GO:0003676 AUP74_RS00070 bf0028ffc89ffd50e0e01f3dcd7017f2 495 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 432 2.0E-155 T 11-11-2016 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 AUP74_RS00070 bf0028ffc89ffd50e0e01f3dcd7017f2 495 SMART SM00316 37 120 1.3E-10 T 11-11-2016 IPR022967 RNA-binding domain, S1 AUP74_RS10325 71d8c51974e3dfc121747df06cc5cfb4 455 Pfam PF00171 Aldehyde dehydrogenase family 4 452 1.7E-139 T 11-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 AUP74_RS10325 71d8c51974e3dfc121747df06cc5cfb4 455 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 259 270 - T 11-11-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 AUP74_RS10325 71d8c51974e3dfc121747df06cc5cfb4 455 SUPERFAMILY SSF53720 4 454 5.37E-134 T 11-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AUP74_RS10325 71d8c51974e3dfc121747df06cc5cfb4 455 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 231 238 - T 11-11-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 AUP74_RS10325 71d8c51974e3dfc121747df06cc5cfb4 455 Gene3D G3DSA:3.40.309.10 245 428 4.2E-66 T 11-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 AUP74_RS10325 71d8c51974e3dfc121747df06cc5cfb4 455 Gene3D G3DSA:3.40.605.10 4 244 7.5E-72 T 11-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AUP74_RS03070 b557f1ff3038be9373c6cc1ed4d1ad34 547 SUPERFAMILY SSF51905 500 536 3.89E-51 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS03070 b557f1ff3038be9373c6cc1ed4d1ad34 547 SUPERFAMILY SSF51905 31 351 3.89E-51 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS03070 b557f1ff3038be9373c6cc1ed4d1ad34 547 Gene3D G3DSA:3.50.50.60 229 342 1.9E-37 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS03070 b557f1ff3038be9373c6cc1ed4d1ad34 547 Gene3D G3DSA:3.50.50.60 31 97 1.9E-37 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS03070 b557f1ff3038be9373c6cc1ed4d1ad34 547 Pfam PF13450 NAD(P)-binding Rossmann-like domain 36 102 3.5E-13 T 11-11-2016 AUP74_RS08815 0553b7ad24b18f93b5d1a5bb97f4ead5 422 PIRSF PIRSF000124 8 422 3.8E-81 T 11-11-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AUP74_RS08815 0553b7ad24b18f93b5d1a5bb97f4ead5 422 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 9 197 3.1E-57 T 11-11-2016 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AUP74_RS08815 0553b7ad24b18f93b5d1a5bb97f4ead5 422 SUPERFAMILY SSF52413 311 421 2.62E-23 T 11-11-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AUP74_RS08815 0553b7ad24b18f93b5d1a5bb97f4ead5 422 SUPERFAMILY SSF48179 215 308 9.01E-29 T 11-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AUP74_RS08815 0553b7ad24b18f93b5d1a5bb97f4ead5 422 PIRSF PIRSF500136 1 422 7.3E-144 T 11-11-2016 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 AUP74_RS08815 0553b7ad24b18f93b5d1a5bb97f4ead5 422 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 325 421 9.1E-20 T 11-11-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AUP74_RS08815 0553b7ad24b18f93b5d1a5bb97f4ead5 422 SMART SM00984 325 422 2.7E-23 T 11-11-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AUP74_RS08815 0553b7ad24b18f93b5d1a5bb97f4ead5 422 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 9 418 3.8E-119 T 11-11-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AUP74_RS08815 0553b7ad24b18f93b5d1a5bb97f4ead5 422 Gene3D G3DSA:3.40.50.720 4 236 1.4E-65 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS08815 0553b7ad24b18f93b5d1a5bb97f4ead5 422 Gene3D G3DSA:3.40.50.720 247 421 2.3E-47 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS08815 0553b7ad24b18f93b5d1a5bb97f4ead5 422 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 215 302 2.3E-26 T 11-11-2016 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AUP74_RS08815 0553b7ad24b18f93b5d1a5bb97f4ead5 422 SUPERFAMILY SSF51735 9 207 6.96E-45 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS01220 920d7a49663aad3a25dc244524d7134c 584 Gene3D G3DSA:1.10.760.10 487 509 1.3E-21 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS01220 920d7a49663aad3a25dc244524d7134c 584 Gene3D G3DSA:1.10.760.10 301 440 1.3E-21 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS01220 920d7a49663aad3a25dc244524d7134c 584 SUPERFAMILY SSF46626 307 441 4.12E-15 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS01220 920d7a49663aad3a25dc244524d7134c 584 SUPERFAMILY SSF46626 488 511 4.12E-15 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS01220 920d7a49663aad3a25dc244524d7134c 584 SUPERFAMILY SSF46626 39 112 1.48E-12 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS01220 920d7a49663aad3a25dc244524d7134c 584 SUPERFAMILY SSF46626 175 220 1.48E-12 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS01220 920d7a49663aad3a25dc244524d7134c 584 Pfam PF03150 Di-haem cytochrome c peroxidase 44 265 7.0E-23 T 11-11-2016 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 AUP74_RS01220 920d7a49663aad3a25dc244524d7134c 584 Gene3D G3DSA:1.10.760.10 41 141 7.0E-15 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS01220 920d7a49663aad3a25dc244524d7134c 584 Gene3D G3DSA:1.10.760.10 178 267 7.0E-15 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS15635 427168164134ab0f4ee0a8071d361afd 251 Gene3D G3DSA:3.40.1180.10 14 242 2.9E-94 T 11-11-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 AUP74_RS15635 427168164134ab0f4ee0a8071d361afd 251 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 13 241 39.62 T 11-11-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 AUP74_RS15635 427168164134ab0f4ee0a8071d361afd 251 SUPERFAMILY SSF64005 12 235 1.83E-83 T 11-11-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 AUP74_RS15635 427168164134ab0f4ee0a8071d361afd 251 Pfam PF01255 Putative undecaprenyl diphosphate synthase 20 240 1.5E-78 T 11-11-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 AUP74_RS15635 427168164134ab0f4ee0a8071d361afd 251 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 14 240 3.8E-87 T 11-11-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 AUP74_RS06060 fee7d9cb887ec509cd8eb045270b420d 345 TIGRFAM TIGR00238 TIGR00238: KamA family protein 23 338 6.6E-104 T 11-11-2016 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase AUP74_RS06060 fee7d9cb887ec509cd8eb045270b420d 345 SUPERFAMILY SSF102114 110 334 1.2E-27 T 11-11-2016 AUP74_RS06060 fee7d9cb887ec509cd8eb045270b420d 345 PIRSF PIRSF004911 5 345 1.7E-110 T 11-11-2016 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase AUP74_RS06060 fee7d9cb887ec509cd8eb045270b420d 345 Gene3D G3DSA:3.20.20.70 115 327 2.6E-15 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS06060 fee7d9cb887ec509cd8eb045270b420d 345 Pfam PF04055 Radical SAM superfamily 129 275 2.5E-7 T 11-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 AUP74_RS06060 fee7d9cb887ec509cd8eb045270b420d 345 TIGRFAM TIGR03821 EFP_modif_epmB: EF-P beta-lysylation protein EpmB 25 345 4.1E-146 T 11-11-2016 IPR022462 Lysine-2,3-aminomutase-like AUP74_RS06470 adcd674d6d6d0a43863091ee0aa856df 211 Pfam PF00325 Bacterial regulatory proteins, crp family 167 197 3.3E-14 T 11-11-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AUP74_RS06470 adcd674d6d6d0a43863091ee0aa856df 211 ProSitePatterns PS00042 Crp-type HTH domain signature. 169 192 - T 11-11-2016 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 AUP74_RS06470 adcd674d6d6d0a43863091ee0aa856df 211 ProSitePatterns PS00888 Cyclic nucleotide-binding domain signature 1. 32 48 - T 11-11-2016 IPR018488 Cyclic nucleotide-binding, conserved site AUP74_RS06470 adcd674d6d6d0a43863091ee0aa856df 211 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 73 90 - T 11-11-2016 IPR018488 Cyclic nucleotide-binding, conserved site AUP74_RS06470 adcd674d6d6d0a43863091ee0aa856df 211 Gene3D G3DSA:2.60.120.10 8 138 1.2E-41 T 11-11-2016 IPR014710 RmlC-like jelly roll fold AUP74_RS06470 adcd674d6d6d0a43863091ee0aa856df 211 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 167 183 4.2E-9 T 11-11-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AUP74_RS06470 adcd674d6d6d0a43863091ee0aa856df 211 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 183 198 4.2E-9 T 11-11-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AUP74_RS06470 adcd674d6d6d0a43863091ee0aa856df 211 SUPERFAMILY SSF51206 14 138 7.2E-38 T 11-11-2016 IPR018490 Cyclic nucleotide-binding-like AUP74_RS06470 adcd674d6d6d0a43863091ee0aa856df 211 Pfam PF00027 Cyclic nucleotide-binding domain 23 111 2.0E-24 T 11-11-2016 IPR000595 Cyclic nucleotide-binding domain AUP74_RS06470 adcd674d6d6d0a43863091ee0aa856df 211 SMART SM00100 5 123 3.2E-28 T 11-11-2016 IPR000595 Cyclic nucleotide-binding domain AUP74_RS06470 adcd674d6d6d0a43863091ee0aa856df 211 SMART SM00419 161 209 1.2E-13 T 11-11-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AUP74_RS06470 adcd674d6d6d0a43863091ee0aa856df 211 SUPERFAMILY SSF46785 140 208 9.67E-16 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS06470 adcd674d6d6d0a43863091ee0aa856df 211 Gene3D G3DSA:1.10.10.10 140 208 8.0E-25 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS14945 8b33fd62fb8906923af08c0a4f89d94d 449 Gene3D G3DSA:3.40.640.10 66 339 2.9E-80 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AUP74_RS14945 8b33fd62fb8906923af08c0a4f89d94d 449 PIRSF PIRSF000521 27 444 1.0E-27 T 11-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AUP74_RS14945 8b33fd62fb8906923af08c0a4f89d94d 449 Gene3D G3DSA:3.90.1150.10 340 445 1.8E-48 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS14945 8b33fd62fb8906923af08c0a4f89d94d 449 Gene3D G3DSA:3.90.1150.10 4 64 1.8E-48 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS14945 8b33fd62fb8906923af08c0a4f89d94d 449 Pfam PF00202 Aminotransferase class-III 29 441 1.5E-101 T 11-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AUP74_RS14945 8b33fd62fb8906923af08c0a4f89d94d 449 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 251 288 - T 11-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AUP74_RS14945 8b33fd62fb8906923af08c0a4f89d94d 449 SUPERFAMILY SSF53383 1 443 6.69E-121 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase AUP74_RS08665 5c3981ba2f0a55ab1d197e8114df4c68 295 Pfam PF04321 RmlD substrate binding domain 1 286 5.3E-106 T 11-11-2016 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581 AUP74_RS08665 5c3981ba2f0a55ab1d197e8114df4c68 295 Gene3D G3DSA:3.40.50.720 1 181 4.7E-31 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS08665 5c3981ba2f0a55ab1d197e8114df4c68 295 SUPERFAMILY SSF51735 1 287 2.31E-97 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS08665 5c3981ba2f0a55ab1d197e8114df4c68 295 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 286 2.6E-106 T 11-11-2016 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581 AUP74_RS08665 5c3981ba2f0a55ab1d197e8114df4c68 295 Gene3D G3DSA:3.90.25.10 213 277 7.7E-30 T 11-11-2016 AUP74_RS02745 5f465189903689a4d29914a1450d8c1a 401 Gene3D G3DSA:1.20.1250.20 28 209 4.1E-16 T 11-11-2016 AUP74_RS02745 5f465189903689a4d29914a1450d8c1a 401 Gene3D G3DSA:1.20.1250.20 223 389 1.0E-9 T 11-11-2016 AUP74_RS02745 5f465189903689a4d29914a1450d8c1a 401 SUPERFAMILY SSF103473 16 392 9.42E-33 T 11-11-2016 IPR020846 Major facilitator superfamily domain AUP74_RS02745 5f465189903689a4d29914a1450d8c1a 401 Pfam PF07690 Major Facilitator Superfamily 29 348 1.1E-14 T 11-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AUP74_RS12970 cfeebaecd24a09c23ea493b4da1f96f4 779 Pfam PF07715 TonB-dependent Receptor Plug Domain 42 148 1.1E-15 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS12970 cfeebaecd24a09c23ea493b4da1f96f4 779 Gene3D G3DSA:2.40.170.20 158 779 7.3E-85 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS12970 cfeebaecd24a09c23ea493b4da1f96f4 779 Gene3D G3DSA:2.170.130.10 23 157 5.3E-31 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS12970 cfeebaecd24a09c23ea493b4da1f96f4 779 SUPERFAMILY SSF56935 561 779 1.94E-110 T 11-11-2016 AUP74_RS12970 cfeebaecd24a09c23ea493b4da1f96f4 779 SUPERFAMILY SSF56935 24 369 1.94E-110 T 11-11-2016 AUP74_RS12970 cfeebaecd24a09c23ea493b4da1f96f4 779 SUPERFAMILY SSF56935 406 528 1.94E-110 T 11-11-2016 AUP74_RS10140 5ac377a543c9b4d99d6479e82e9b4bf9 878 SUPERFAMILY SSF63737 5 197 2.62E-43 T 11-11-2016 AUP74_RS10140 5ac377a543c9b4d99d6479e82e9b4bf9 878 Gene3D G3DSA:1.10.390.10 313 456 1.8E-32 T 11-11-2016 AUP74_RS10140 5ac377a543c9b4d99d6479e82e9b4bf9 878 Gene3D G3DSA:1.25.50.10 550 876 6.6E-118 T 11-11-2016 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal AUP74_RS10140 5ac377a543c9b4d99d6479e82e9b4bf9 878 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 263 273 1.8E-8 T 11-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AUP74_RS10140 5ac377a543c9b4d99d6479e82e9b4bf9 878 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 318 330 1.8E-8 T 11-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AUP74_RS10140 5ac377a543c9b4d99d6479e82e9b4bf9 878 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 181 196 1.8E-8 T 11-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AUP74_RS10140 5ac377a543c9b4d99d6479e82e9b4bf9 878 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 299 314 1.8E-8 T 11-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AUP74_RS10140 5ac377a543c9b4d99d6479e82e9b4bf9 878 SUPERFAMILY SSF55486 208 455 3.85E-76 T 11-11-2016 AUP74_RS10140 5ac377a543c9b4d99d6479e82e9b4bf9 878 TIGRFAM TIGR02414 pepN_proteo: aminopeptidase N 13 875 0.0 T 11-11-2016 IPR012779 Peptidase M1, alanyl aminopeptidase GO:0008270 AUP74_RS10140 5ac377a543c9b4d99d6479e82e9b4bf9 878 Pfam PF01433 Peptidase family M1 119 389 1.1E-68 T 11-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AUP74_RS10140 5ac377a543c9b4d99d6479e82e9b4bf9 878 Pfam PF11940 Domain of unknown function (DUF3458) 465 833 2.3E-139 T 11-11-2016 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal AUP74_RS07685 358c1cae30cbd40dee0f73d6a3f8c399 853 Gene3D G3DSA:3.40.190.10 390 470 6.4E-18 T 11-11-2016 AUP74_RS07685 358c1cae30cbd40dee0f73d6a3f8c399 853 Gene3D G3DSA:3.40.190.10 185 243 7.1E-16 T 11-11-2016 AUP74_RS07685 358c1cae30cbd40dee0f73d6a3f8c399 853 Gene3D G3DSA:3.40.190.10 582 622 6.4E-18 T 11-11-2016 AUP74_RS07685 358c1cae30cbd40dee0f73d6a3f8c399 853 Gene3D G3DSA:3.40.190.10 348 375 7.1E-16 T 11-11-2016 AUP74_RS07685 358c1cae30cbd40dee0f73d6a3f8c399 853 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 399 605 6.8E-27 T 11-11-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AUP74_RS07685 358c1cae30cbd40dee0f73d6a3f8c399 853 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 189 375 5.3E-28 T 11-11-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AUP74_RS07685 358c1cae30cbd40dee0f73d6a3f8c399 853 Gene3D G3DSA:3.40.190.10 471 562 7.4E-7 T 11-11-2016 AUP74_RS07685 358c1cae30cbd40dee0f73d6a3f8c399 853 Gene3D G3DSA:3.40.190.10 244 330 2.9E-13 T 11-11-2016 AUP74_RS07685 358c1cae30cbd40dee0f73d6a3f8c399 853 SUPERFAMILY SSF53955 641 811 4.36E-39 T 11-11-2016 IPR023346 Lysozyme-like domain AUP74_RS07685 358c1cae30cbd40dee0f73d6a3f8c399 853 SUPERFAMILY SSF53850 159 376 2.45E-32 T 11-11-2016 AUP74_RS07685 358c1cae30cbd40dee0f73d6a3f8c399 853 Pfam PF01464 Transglycosylase SLT domain 645 756 6.0E-24 T 11-11-2016 IPR008258 Transglycosylase SLT domain 1 AUP74_RS07685 358c1cae30cbd40dee0f73d6a3f8c399 853 SUPERFAMILY SSF53850 385 623 1.77E-33 T 11-11-2016 AUP74_RS07685 358c1cae30cbd40dee0f73d6a3f8c399 853 Gene3D G3DSA:1.10.530.10 635 750 3.2E-42 T 11-11-2016 AUP74_RS07685 358c1cae30cbd40dee0f73d6a3f8c399 853 Gene3D G3DSA:1.10.530.10 786 808 3.2E-42 T 11-11-2016 AUP74_RS07685 358c1cae30cbd40dee0f73d6a3f8c399 853 SMART SM00062 167 385 5.6E-16 T 11-11-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AUP74_RS07685 358c1cae30cbd40dee0f73d6a3f8c399 853 SMART SM00062 393 623 2.0E-18 T 11-11-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AUP74_RS13120 bab7b0781052c108e35e86d0a802f488 565 PIRSF PIRSF000137 1 543 3.5E-143 T 11-11-2016 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 AUP74_RS13120 bab7b0781052c108e35e86d0a802f488 565 SUPERFAMILY SSF51905 477 535 9.07E-87 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS13120 bab7b0781052c108e35e86d0a802f488 565 SUPERFAMILY SSF51905 7 294 9.07E-87 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS13120 bab7b0781052c108e35e86d0a802f488 565 Pfam PF05199 GMC oxidoreductase 392 527 2.4E-39 T 11-11-2016 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 AUP74_RS13120 bab7b0781052c108e35e86d0a802f488 565 Pfam PF00732 GMC oxidoreductase 10 301 1.2E-91 T 11-11-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 AUP74_RS13120 bab7b0781052c108e35e86d0a802f488 565 Gene3D G3DSA:3.50.50.60 193 319 1.2E-122 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS13120 bab7b0781052c108e35e86d0a802f488 565 Gene3D G3DSA:3.50.50.60 5 131 1.2E-122 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS13120 bab7b0781052c108e35e86d0a802f488 565 Gene3D G3DSA:3.50.50.60 471 534 1.2E-122 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS13120 bab7b0781052c108e35e86d0a802f488 565 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 260 274 - T 11-11-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 AUP74_RS13120 bab7b0781052c108e35e86d0a802f488 565 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 87 110 - T 11-11-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 AUP74_RS13120 bab7b0781052c108e35e86d0a802f488 565 TIGRFAM TIGR01810 betA: choline dehydrogenase 11 536 9.4E-237 T 11-11-2016 IPR011533 Oxygen-dependent choline dehydrogenase GO:0008812|GO:0019285 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494 AUP74_RS13120 bab7b0781052c108e35e86d0a802f488 565 SUPERFAMILY SSF54373 296 478 8.04E-58 T 11-11-2016 AUP74_RS09785 7e238541de69969ce1050157903bb6a2 238 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 4 227 1.7E-32 T 11-11-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AUP74_RS09785 7e238541de69969ce1050157903bb6a2 238 PIRSF PIRSF015601 2 235 2.6E-51 T 11-11-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AUP74_RS09785 7e238541de69969ce1050157903bb6a2 238 Pfam PF04452 RNA methyltransferase 17 234 1.9E-48 T 11-11-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AUP74_RS09785 7e238541de69969ce1050157903bb6a2 238 SUPERFAMILY SSF88697 7 66 1.12E-5 T 11-11-2016 IPR015947 PUA-like domain AUP74_RS09785 7e238541de69969ce1050157903bb6a2 238 Gene3D G3DSA:3.40.1280.10 5 233 4.4E-62 T 11-11-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AUP74_RS09785 7e238541de69969ce1050157903bb6a2 238 SUPERFAMILY SSF75217 72 234 2.09E-36 T 11-11-2016 IPR029028 Alpha/beta knot methyltransferases AUP74_RS14350 daac6bee568c39200d323329a8ecec17 405 SUPERFAMILY SSF55973 6 110 5.89E-44 T 11-11-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AUP74_RS14350 daac6bee568c39200d323329a8ecec17 405 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 235 370 6.9E-66 T 11-11-2016 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AUP74_RS14350 daac6bee568c39200d323329a8ecec17 405 Gene3D G3DSA:3.30.300.10 137 235 5.8E-42 T 11-11-2016 AUP74_RS14350 daac6bee568c39200d323329a8ecec17 405 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 117 127 - T 11-11-2016 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AUP74_RS14350 daac6bee568c39200d323329a8ecec17 405 Pfam PF02772 S-adenosylmethionine synthetase, central domain 115 233 4.1E-44 T 11-11-2016 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AUP74_RS14350 daac6bee568c39200d323329a8ecec17 405 Gene3D G3DSA:3.30.300.10 12 136 2.8E-46 T 11-11-2016 AUP74_RS14350 daac6bee568c39200d323329a8ecec17 405 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 261 269 - T 11-11-2016 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AUP74_RS14350 daac6bee568c39200d323329a8ecec17 405 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 6 370 5.7E-180 T 11-11-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AUP74_RS14350 daac6bee568c39200d323329a8ecec17 405 PIRSF PIRSF000497 1 404 1.4E-168 T 11-11-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AUP74_RS14350 daac6bee568c39200d323329a8ecec17 405 SUPERFAMILY SSF55973 112 234 5.1E-50 T 11-11-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AUP74_RS14350 daac6bee568c39200d323329a8ecec17 405 Gene3D G3DSA:3.30.300.10 246 403 1.5E-68 T 11-11-2016 AUP74_RS14350 daac6bee568c39200d323329a8ecec17 405 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 6 101 1.7E-39 T 11-11-2016 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AUP74_RS14350 daac6bee568c39200d323329a8ecec17 405 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 3 403 56.084 T 11-11-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AUP74_RS14350 daac6bee568c39200d323329a8ecec17 405 SUPERFAMILY SSF55973 235 367 5.49E-64 T 11-11-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AUP74_RS13595 74afb633356390bbaf255bf50546029e 237 SUPERFAMILY SSF51735 8 224 1.83E-43 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS13595 74afb633356390bbaf255bf50546029e 237 Pfam PF00106 short chain dehydrogenase 8 150 8.9E-32 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS13595 74afb633356390bbaf255bf50546029e 237 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 94 122 - T 11-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AUP74_RS13595 74afb633356390bbaf255bf50546029e 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 36 47 9.1E-8 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS13595 74afb633356390bbaf255bf50546029e 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 145 9.1E-8 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS13595 74afb633356390bbaf255bf50546029e 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 107 126 9.1E-8 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS13595 74afb633356390bbaf255bf50546029e 237 Gene3D G3DSA:3.40.50.720 8 154 7.2E-38 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS09955 561bb5b638d1723362b6209c8ad9e9fd 284 ProSitePatterns PS00194 Thioredoxin family active site. 27 45 - T 11-11-2016 IPR017937 Thioredoxin, conserved site GO:0045454 AUP74_RS09955 561bb5b638d1723362b6209c8ad9e9fd 284 Pfam PF14559 Tetratricopeptide repeat 124 190 5.0E-15 T 11-11-2016 AUP74_RS09955 561bb5b638d1723362b6209c8ad9e9fd 284 Pfam PF00085 Thioredoxin 7 108 1.1E-26 T 11-11-2016 IPR013766 Thioredoxin domain GO:0045454 AUP74_RS09955 561bb5b638d1723362b6209c8ad9e9fd 284 Pfam PF14561 Tetratricopeptide repeat 195 284 3.0E-27 T 11-11-2016 AUP74_RS09955 561bb5b638d1723362b6209c8ad9e9fd 284 Gene3D G3DSA:1.25.40.10 197 284 3.2E-29 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS09955 561bb5b638d1723362b6209c8ad9e9fd 284 TIGRFAM TIGR01068 thioredoxin: thioredoxin 21 109 1.3E-30 T 11-11-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 AUP74_RS09955 561bb5b638d1723362b6209c8ad9e9fd 284 Gene3D G3DSA:3.40.30.10 4 109 8.4E-34 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS09955 561bb5b638d1723362b6209c8ad9e9fd 284 PRINTS PR00421 Thioredoxin family signature 26 34 1.6E-6 T 11-11-2016 AUP74_RS09955 561bb5b638d1723362b6209c8ad9e9fd 284 PRINTS PR00421 Thioredoxin family signature 34 43 1.6E-6 T 11-11-2016 AUP74_RS09955 561bb5b638d1723362b6209c8ad9e9fd 284 PRINTS PR00421 Thioredoxin family signature 74 85 1.6E-6 T 11-11-2016 AUP74_RS09955 561bb5b638d1723362b6209c8ad9e9fd 284 SUPERFAMILY SSF52833 4 112 2.18E-36 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS09955 561bb5b638d1723362b6209c8ad9e9fd 284 SUPERFAMILY SSF48452 105 247 2.2E-11 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS09955 561bb5b638d1723362b6209c8ad9e9fd 284 Gene3D G3DSA:1.25.40.10 110 196 1.4E-25 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS06895 c29c274c3cb6da397e66df5e751dd91c 130 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 130 31.23 T 11-11-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06895 c29c274c3cb6da397e66df5e751dd91c 130 Pfam PF00410 Ribosomal protein S8 5 130 6.9E-48 T 11-11-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06895 c29c274c3cb6da397e66df5e751dd91c 130 Gene3D G3DSA:3.30.1370.30 2 71 1.9E-25 T 11-11-2016 AUP74_RS06895 c29c274c3cb6da397e66df5e751dd91c 130 Gene3D G3DSA:3.30.1490.10 74 130 6.3E-28 T 11-11-2016 AUP74_RS06895 c29c274c3cb6da397e66df5e751dd91c 130 ProSitePatterns PS00053 Ribosomal protein S8 signature. 100 117 - T 11-11-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06895 c29c274c3cb6da397e66df5e751dd91c 130 SUPERFAMILY SSF56047 2 130 1.03E-44 T 11-11-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS03150 64141a52ebffc41fcfea78f1646cdb17 1121 Gene3D G3DSA:3.30.565.10 821 975 2.1E-36 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS03150 64141a52ebffc41fcfea78f1646cdb17 1121 SUPERFAMILY SSF55874 808 973 9.3E-37 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS03150 64141a52ebffc41fcfea78f1646cdb17 1121 SUPERFAMILY SSF52172 996 1110 5.12E-20 T 11-11-2016 IPR011006 CheY-like superfamily AUP74_RS03150 64141a52ebffc41fcfea78f1646cdb17 1121 SUPERFAMILY SSF55785 602 710 8.95E-8 T 11-11-2016 IPR000014 PAS domain AUP74_RS03150 64141a52ebffc41fcfea78f1646cdb17 1121 Pfam PF00512 His Kinase A (phospho-acceptor) domain 754 818 1.4E-9 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS03150 64141a52ebffc41fcfea78f1646cdb17 1121 Gene3D G3DSA:3.40.50.2300 993 1109 6.9E-19 T 11-11-2016 AUP74_RS03150 64141a52ebffc41fcfea78f1646cdb17 1121 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 863 973 1.8E-19 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS03150 64141a52ebffc41fcfea78f1646cdb17 1121 SMART SM00387 862 975 1.7E-25 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS03150 64141a52ebffc41fcfea78f1646cdb17 1121 SUPERFAMILY SSF47384 739 819 1.04E-11 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS03150 64141a52ebffc41fcfea78f1646cdb17 1121 Gene3D G3DSA:1.10.287.130 746 814 4.6E-8 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS03150 64141a52ebffc41fcfea78f1646cdb17 1121 Pfam PF12860 PAS fold 606 718 8.1E-45 T 11-11-2016 AUP74_RS03150 64141a52ebffc41fcfea78f1646cdb17 1121 Gene3D G3DSA:3.30.450.20 601 714 2.4E-11 T 11-11-2016 AUP74_RS03150 64141a52ebffc41fcfea78f1646cdb17 1121 SMART SM00448 996 1105 2.7E-17 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS03150 64141a52ebffc41fcfea78f1646cdb17 1121 Pfam PF00072 Response regulator receiver domain 998 1105 8.4E-14 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS03150 64141a52ebffc41fcfea78f1646cdb17 1121 PRINTS PR00344 Bacterial sensor protein C-terminal signature 898 912 2.5E-9 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS03150 64141a52ebffc41fcfea78f1646cdb17 1121 PRINTS PR00344 Bacterial sensor protein C-terminal signature 916 926 2.5E-9 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS03150 64141a52ebffc41fcfea78f1646cdb17 1121 PRINTS PR00344 Bacterial sensor protein C-terminal signature 935 953 2.5E-9 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS03150 64141a52ebffc41fcfea78f1646cdb17 1121 PRINTS PR00344 Bacterial sensor protein C-terminal signature 959 972 2.5E-9 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS03150 64141a52ebffc41fcfea78f1646cdb17 1121 SMART SM00388 753 818 6.5E-10 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS06215 b1f715105d78ff9efeec8d963eed0272 272 SMART SM00448 8 118 3.1E-29 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS06215 b1f715105d78ff9efeec8d963eed0272 272 SUPERFAMILY SSF52172 7 130 2.85E-32 T 11-11-2016 IPR011006 CheY-like superfamily AUP74_RS06215 b1f715105d78ff9efeec8d963eed0272 272 SMART SM00850 176 272 5.8E-31 T 11-11-2016 IPR007492 LytTR DNA-binding domain GO:0003677 AUP74_RS06215 b1f715105d78ff9efeec8d963eed0272 272 Gene3D G3DSA:2.20.25.10 238 268 7.0E-4 T 11-11-2016 AUP74_RS06215 b1f715105d78ff9efeec8d963eed0272 272 Pfam PF00072 Response regulator receiver domain 11 118 1.8E-25 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS06215 b1f715105d78ff9efeec8d963eed0272 272 Gene3D G3DSA:3.40.50.2300 4 129 2.4E-32 T 11-11-2016 AUP74_RS06215 b1f715105d78ff9efeec8d963eed0272 272 Pfam PF04397 LytTr DNA-binding domain 177 270 5.9E-24 T 11-11-2016 IPR007492 LytTR DNA-binding domain GO:0003677 AUP74_RS06215 b1f715105d78ff9efeec8d963eed0272 272 Gene3D G3DSA:2.40.50.40 167 234 1.4E-19 T 11-11-2016 AUP74_RS16885 6b3b863501dcfece2387bec0b4a8c19a 394 Hamap MF_00066 Sulfate adenylyltransferase [sat]. 27 393 46.079 T 11-11-2016 IPR020792 Sulphate adenylyltransferase, prokaryotic-type GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 AUP74_RS16885 6b3b863501dcfece2387bec0b4a8c19a 394 Gene3D G3DSA:3.40.50.620 187 393 4.0E-77 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS16885 6b3b863501dcfece2387bec0b4a8c19a 394 Gene3D G3DSA:3.10.400.10 2 186 5.1E-51 T 11-11-2016 AUP74_RS16885 6b3b863501dcfece2387bec0b4a8c19a 394 SUPERFAMILY SSF52374 175 393 5.33E-78 T 11-11-2016 AUP74_RS16885 6b3b863501dcfece2387bec0b4a8c19a 394 Pfam PF01747 ATP-sulfurylase 178 389 4.7E-75 T 11-11-2016 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 AUP74_RS16885 6b3b863501dcfece2387bec0b4a8c19a 394 SUPERFAMILY SSF88697 2 171 8.55E-43 T 11-11-2016 IPR015947 PUA-like domain AUP74_RS16885 6b3b863501dcfece2387bec0b4a8c19a 394 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 4 389 1.6E-123 T 11-11-2016 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 AUP74_RS16885 6b3b863501dcfece2387bec0b4a8c19a 394 Pfam PF14306 PUA-like domain 3 165 8.1E-36 T 11-11-2016 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 AUP74_RS04750 8b710d2d5be9ac87eedd38e8d1eda74a 214 Pfam PF01613 Flavin reductase like domain 35 168 1.0E-16 T 11-11-2016 IPR002563 Flavin reductase like domain GO:0010181 AUP74_RS04750 8b710d2d5be9ac87eedd38e8d1eda74a 214 SUPERFAMILY SSF50475 9 200 2.4E-34 T 11-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 AUP74_RS04750 8b710d2d5be9ac87eedd38e8d1eda74a 214 SMART SM00903 27 177 0.0013 T 11-11-2016 IPR002563 Flavin reductase like domain GO:0010181 AUP74_RS04750 8b710d2d5be9ac87eedd38e8d1eda74a 214 Gene3D G3DSA:2.30.110.10 18 194 1.8E-43 T 11-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 AUP74_RS14835 429879a6389ed45698232fd98adf8f8a 224 SUPERFAMILY SSF56784 1 216 6.04E-57 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS14835 429879a6389ed45698232fd98adf8f8a 224 Gene3D G3DSA:1.10.150.240 16 83 1.6E-8 T 11-11-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 AUP74_RS14835 429879a6389ed45698232fd98adf8f8a 224 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 4 214 2.2E-50 T 11-11-2016 IPR006346 2-phosphoglycolate phosphatase, prokaryotic GO:0008967|GO:0046295 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 AUP74_RS14835 429879a6389ed45698232fd98adf8f8a 224 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 77 182 3.7E-12 T 11-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 AUP74_RS14835 429879a6389ed45698232fd98adf8f8a 224 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 87 178 4.4E-10 T 11-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 AUP74_RS14835 429879a6389ed45698232fd98adf8f8a 224 Gene3D G3DSA:3.40.50.1000 1 15 3.2E-42 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS14835 429879a6389ed45698232fd98adf8f8a 224 Gene3D G3DSA:3.40.50.1000 88 216 3.2E-42 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS14835 429879a6389ed45698232fd98adf8f8a 224 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 183 1.1E-36 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS07165 578df11781a873cb2d3d6ba1966fc37d 532 Gene3D G3DSA:3.30.450.20 200 238 1.2E-5 T 11-11-2016 AUP74_RS07165 578df11781a873cb2d3d6ba1966fc37d 532 Gene3D G3DSA:3.30.565.10 377 524 3.8E-28 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS07165 578df11781a873cb2d3d6ba1966fc37d 532 SMART SM00387 417 528 1.8E-25 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS07165 578df11781a873cb2d3d6ba1966fc37d 532 SUPERFAMILY SSF55874 367 524 1.11E-27 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS07165 578df11781a873cb2d3d6ba1966fc37d 532 PRINTS PR00344 Bacterial sensor protein C-terminal signature 488 506 3.3E-9 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS07165 578df11781a873cb2d3d6ba1966fc37d 532 PRINTS PR00344 Bacterial sensor protein C-terminal signature 459 473 3.3E-9 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS07165 578df11781a873cb2d3d6ba1966fc37d 532 PRINTS PR00344 Bacterial sensor protein C-terminal signature 477 487 3.3E-9 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS07165 578df11781a873cb2d3d6ba1966fc37d 532 SMART SM00388 310 376 5.1E-15 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS07165 578df11781a873cb2d3d6ba1966fc37d 532 Pfam PF00512 His Kinase A (phospho-acceptor) domain 310 374 4.4E-13 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS07165 578df11781a873cb2d3d6ba1966fc37d 532 SUPERFAMILY SSF47384 303 374 8.44E-13 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS07165 578df11781a873cb2d3d6ba1966fc37d 532 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 418 522 5.0E-16 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS07165 578df11781a873cb2d3d6ba1966fc37d 532 Gene3D G3DSA:1.10.287.130 308 372 7.1E-12 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS02590 1ef5dca2dcbcb2f7ef6a859b958b8f6d 69 SUPERFAMILY SSF50249 3 68 4.14E-23 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS02590 1ef5dca2dcbcb2f7ef6a859b958b8f6d 69 Gene3D G3DSA:2.40.50.140 5 68 2.1E-28 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS02590 1ef5dca2dcbcb2f7ef6a859b958b8f6d 69 Pfam PF00313 'Cold-shock' DNA-binding domain 5 68 1.2E-27 T 11-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AUP74_RS02590 1ef5dca2dcbcb2f7ef6a859b958b8f6d 69 SMART SM00357 6 69 6.7E-27 T 11-11-2016 IPR011129 Cold shock protein GO:0003676 AUP74_RS02590 1ef5dca2dcbcb2f7ef6a859b958b8f6d 69 ProSitePatterns PS00352 'Cold-shock' domain signature. 18 36 - T 11-11-2016 IPR019844 Cold-shock conserved site AUP74_RS02590 1ef5dca2dcbcb2f7ef6a859b958b8f6d 69 PIRSF PIRSF002599 1 69 7.1E-23 T 11-11-2016 IPR012156 Cold shock, CspA GO:0003676 AUP74_RS02590 1ef5dca2dcbcb2f7ef6a859b958b8f6d 69 PRINTS PR00050 Cold shock protein signature 27 36 2.9E-16 T 11-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AUP74_RS02590 1ef5dca2dcbcb2f7ef6a859b958b8f6d 69 PRINTS PR00050 Cold shock protein signature 7 22 2.9E-16 T 11-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AUP74_RS02590 1ef5dca2dcbcb2f7ef6a859b958b8f6d 69 PRINTS PR00050 Cold shock protein signature 42 60 2.9E-16 T 11-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AUP74_RS06410 ab5ecc2438873b01bb3ee15e19ccf6b1 265 SUPERFAMILY SSF53335 15 261 2.89E-81 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS06410 ab5ecc2438873b01bb3ee15e19ccf6b1 265 Pfam PF00398 Ribosomal RNA adenine dimethylase 7 260 3.2E-69 T 11-11-2016 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm AUP74_RS06410 ab5ecc2438873b01bb3ee15e19ccf6b1 265 Gene3D G3DSA:3.40.50.150 6 195 1.2E-72 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS06410 ab5ecc2438873b01bb3ee15e19ccf6b1 265 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 39 66 - T 11-11-2016 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 AUP74_RS06410 ab5ecc2438873b01bb3ee15e19ccf6b1 265 SMART SM00650 23 194 4.8E-86 T 11-11-2016 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 AUP74_RS06410 ab5ecc2438873b01bb3ee15e19ccf6b1 265 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 7 261 58.637 T 11-11-2016 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 AUP74_RS06410 ab5ecc2438873b01bb3ee15e19ccf6b1 265 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 8 260 1.3E-87 T 11-11-2016 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 AUP74_RS06410 ab5ecc2438873b01bb3ee15e19ccf6b1 265 Gene3D G3DSA:1.10.8.100 197 262 7.4E-24 T 11-11-2016 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201 AUP74_RS00620 cb375f160833442929289d054c0f433a 204 SUPERFAMILY SSF111304 2 197 6.41E-71 T 11-11-2016 IPR023627 Recombination protein RecR AUP74_RS00620 cb375f160833442929289d054c0f433a 204 SMART SM00493 79 164 4.1E-17 T 11-11-2016 IPR006171 Toprim domain AUP74_RS00620 cb375f160833442929289d054c0f433a 204 ProSitePatterns PS01300 RecR protein signature. 56 77 - T 11-11-2016 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 AUP74_RS00620 cb375f160833442929289d054c0f433a 204 TIGRFAM TIGR00615 recR: recombination protein RecR 2 195 3.0E-73 T 11-11-2016 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 AUP74_RS00620 cb375f160833442929289d054c0f433a 204 Hamap MF_00017 Recombination protein RecR [recR]. 1 197 98.253 T 11-11-2016 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 AUP74_RS00620 cb375f160833442929289d054c0f433a 204 Pfam PF02132 RecR protein 40 77 2.1E-12 T 11-11-2016 IPR023628 Recombination protein RecR, C4-type zinc finger AUP74_RS00620 cb375f160833442929289d054c0f433a 204 Pfam PF13662 Toprim domain 80 170 6.5E-24 T 11-11-2016 IPR006171 Toprim domain AUP74_RS11580 a372b7ae9c8a1a7e9f3f9d58e6f26b3e 169 PIRSF PIRSF001467 1 162 3.4E-30 T 11-11-2016 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 AUP74_RS11580 a372b7ae9c8a1a7e9f3f9d58e6f26b3e 169 SUPERFAMILY SSF50891 1 162 1.24E-60 T 11-11-2016 IPR029000 Cyclophilin-like domain AUP74_RS11580 a372b7ae9c8a1a7e9f3f9d58e6f26b3e 169 Gene3D G3DSA:2.40.100.10 2 162 5.5E-56 T 11-11-2016 IPR029000 Cyclophilin-like domain AUP74_RS11580 a372b7ae9c8a1a7e9f3f9d58e6f26b3e 169 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 15 30 3.9E-13 T 11-11-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 AUP74_RS11580 a372b7ae9c8a1a7e9f3f9d58e6f26b3e 169 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 118 133 3.9E-13 T 11-11-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 AUP74_RS11580 a372b7ae9c8a1a7e9f3f9d58e6f26b3e 169 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 41 53 3.9E-13 T 11-11-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 AUP74_RS11580 a372b7ae9c8a1a7e9f3f9d58e6f26b3e 169 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 2 160 1.2E-49 T 11-11-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 AUP74_RS11580 a372b7ae9c8a1a7e9f3f9d58e6f26b3e 169 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 36 53 - T 11-11-2016 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 AUP74_RS10485 206447c363c7a351941d52314b3f2e1b 174 Pfam PF00258 Flavodoxin 7 162 3.9E-27 T 11-11-2016 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 AUP74_RS10485 206447c363c7a351941d52314b3f2e1b 174 TIGRFAM TIGR01752 flav_long: flavodoxin 5 170 8.9E-67 T 11-11-2016 IPR010086 Flavodoxin, long chain GO:0010181 AUP74_RS10485 206447c363c7a351941d52314b3f2e1b 174 Gene3D G3DSA:3.40.50.360 5 170 2.0E-56 T 11-11-2016 IPR029039 Flavoprotein-like domain AUP74_RS10485 206447c363c7a351941d52314b3f2e1b 174 PIRSF PIRSF038996 2 174 1.2E-59 T 11-11-2016 IPR010086 Flavodoxin, long chain GO:0010181 AUP74_RS10485 206447c363c7a351941d52314b3f2e1b 174 SUPERFAMILY SSF52218 5 172 1.86E-46 T 11-11-2016 IPR029039 Flavoprotein-like domain AUP74_RS10485 206447c363c7a351941d52314b3f2e1b 174 ProSitePatterns PS00201 Flavodoxin signature. 7 23 - T 11-11-2016 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 AUP74_RS09220 35926f4f545df7b1e887f957a13eaca2 400 Pfam PF03616 Sodium/glutamate symporter 5 368 3.8E-122 T 11-11-2016 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 AUP74_RS09220 35926f4f545df7b1e887f957a13eaca2 400 TIGRFAM TIGR00210 gltS: sodium/glutamate symporter 6 399 3.2E-145 T 11-11-2016 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 AUP74_RS15465 8b9f25f28cd9755b1e3c65a4bb4a89f4 178 SUPERFAMILY SSF52980 4 177 3.75E-74 T 11-11-2016 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AUP74_RS15465 8b9f25f28cd9755b1e3c65a4bb4a89f4 178 Gene3D G3DSA:3.10.640.10 1 178 2.6E-82 T 11-11-2016 AUP74_RS15465 8b9f25f28cd9755b1e3c65a4bb4a89f4 178 SMART SM01322 1 176 3.2E-118 T 11-11-2016 IPR009822 YaeQ AUP74_RS15465 8b9f25f28cd9755b1e3c65a4bb4a89f4 178 PIRSF PIRSF011484 1 178 4.9E-75 T 11-11-2016 IPR009822 YaeQ AUP74_RS15465 8b9f25f28cd9755b1e3c65a4bb4a89f4 178 Pfam PF07152 YaeQ protein 1 173 1.0E-78 T 11-11-2016 IPR009822 YaeQ AUP74_RS09350 f89f38589f1f51253b6928635d7ed4bf 898 Gene3D G3DSA:2.60.40.320 840 887 1.7E-10 T 11-11-2016 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 AUP74_RS09350 f89f38589f1f51253b6928635d7ed4bf 898 Pfam PF03174 Chitobiase/beta-hexosaminidase C-terminal domain 814 885 1.2E-16 T 11-11-2016 AUP74_RS09350 f89f38589f1f51253b6928635d7ed4bf 898 SMART SM01081 33 203 7.7E-42 T 11-11-2016 IPR004866 Chitobiase/beta-hexosaminidases, N-terminal domain KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 AUP74_RS09350 f89f38589f1f51253b6928635d7ed4bf 898 SUPERFAMILY SSF81296 790 888 3.78E-23 T 11-11-2016 IPR014756 Immunoglobulin E-set AUP74_RS09350 f89f38589f1f51253b6928635d7ed4bf 898 PRINTS PR00738 Glycosyl hydrolase family 20 signature 304 324 5.0E-48 T 11-11-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 AUP74_RS09350 f89f38589f1f51253b6928635d7ed4bf 898 PRINTS PR00738 Glycosyl hydrolase family 20 signature 535 548 5.0E-48 T 11-11-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 AUP74_RS09350 f89f38589f1f51253b6928635d7ed4bf 898 PRINTS PR00738 Glycosyl hydrolase family 20 signature 508 526 5.0E-48 T 11-11-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 AUP74_RS09350 f89f38589f1f51253b6928635d7ed4bf 898 PRINTS PR00738 Glycosyl hydrolase family 20 signature 337 354 5.0E-48 T 11-11-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 AUP74_RS09350 f89f38589f1f51253b6928635d7ed4bf 898 PRINTS PR00738 Glycosyl hydrolase family 20 signature 738 754 5.0E-48 T 11-11-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 AUP74_RS09350 f89f38589f1f51253b6928635d7ed4bf 898 PRINTS PR00738 Glycosyl hydrolase family 20 signature 443 460 5.0E-48 T 11-11-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 AUP74_RS09350 f89f38589f1f51253b6928635d7ed4bf 898 PRINTS PR00738 Glycosyl hydrolase family 20 signature 366 387 5.0E-48 T 11-11-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 AUP74_RS09350 f89f38589f1f51253b6928635d7ed4bf 898 PRINTS PR00738 Glycosyl hydrolase family 20 signature 756 773 5.0E-48 T 11-11-2016 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 AUP74_RS09350 f89f38589f1f51253b6928635d7ed4bf 898 Gene3D G3DSA:3.20.20.80 341 839 8.4E-136 T 11-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 AUP74_RS09350 f89f38589f1f51253b6928635d7ed4bf 898 Gene3D G3DSA:3.30.379.10 222 340 8.8E-19 T 11-11-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 AUP74_RS09350 f89f38589f1f51253b6928635d7ed4bf 898 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 222 340 7.4E-13 T 11-11-2016 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 AUP74_RS09350 f89f38589f1f51253b6928635d7ed4bf 898 Gene3D G3DSA:2.60.40.290 28 170 1.0E-34 T 11-11-2016 IPR012291 Cellulose-binding family II/chitobiase, carbohydrate-binding domain GO:0004553|GO:0030247 AUP74_RS09350 f89f38589f1f51253b6928635d7ed4bf 898 Pfam PF03173 Putative carbohydrate binding domain 37 201 8.8E-38 T 11-11-2016 IPR004866 Chitobiase/beta-hexosaminidases, N-terminal domain KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 AUP74_RS09350 f89f38589f1f51253b6928635d7ed4bf 898 SUPERFAMILY SSF49384 29 205 3.14E-40 T 11-11-2016 IPR008965 Carbohydrate-binding domain GO:0030246 AUP74_RS09350 f89f38589f1f51253b6928635d7ed4bf 898 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 343 774 1.8E-98 T 11-11-2016 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 AUP74_RS09350 f89f38589f1f51253b6928635d7ed4bf 898 SUPERFAMILY SSF51445 343 778 7.72E-127 T 11-11-2016 IPR017853 Glycoside hydrolase superfamily AUP74_RS09350 f89f38589f1f51253b6928635d7ed4bf 898 SUPERFAMILY SSF55545 219 342 3.01E-21 T 11-11-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 AUP74_RS02720 ec55510320bfa818d156f8a8076dbd88 509 Pfam PF01752 Collagenase 131 240 4.2E-6 T 11-11-2016 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 AUP74_RS02720 ec55510320bfa818d156f8a8076dbd88 509 Gene3D G3DSA:1.25.40.10 319 365 9.0E-6 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS12390 21a6b59ae4e163ed8c6880fb35d21056 333 SMART SM00846 3 152 1.2E-62 T 11-11-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS12390 21a6b59ae4e163ed8c6880fb35d21056 333 PIRSF PIRSF000149 1 333 4.1E-117 T 11-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS12390 21a6b59ae4e163ed8c6880fb35d21056 333 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 313 4.5E-62 T 11-11-2016 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS12390 21a6b59ae4e163ed8c6880fb35d21056 333 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 152 9.1E-47 T 11-11-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS12390 21a6b59ae4e163ed8c6880fb35d21056 333 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 324 3.3E-119 T 11-11-2016 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS12390 21a6b59ae4e163ed8c6880fb35d21056 333 Gene3D G3DSA:3.40.50.720 1 160 1.5E-56 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS12390 21a6b59ae4e163ed8c6880fb35d21056 333 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 11-11-2016 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS12390 21a6b59ae4e163ed8c6880fb35d21056 333 SUPERFAMILY SSF51735 1 180 7.64E-50 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS12390 21a6b59ae4e163ed8c6880fb35d21056 333 SUPERFAMILY SSF55347 152 314 9.52E-67 T 11-11-2016 AUP74_RS12390 21a6b59ae4e163ed8c6880fb35d21056 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 108 121 5.3E-31 T 11-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS12390 21a6b59ae4e163ed8c6880fb35d21056 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 5.3E-31 T 11-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS12390 21a6b59ae4e163ed8c6880fb35d21056 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 5.3E-31 T 11-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS12390 21a6b59ae4e163ed8c6880fb35d21056 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 5.3E-31 T 11-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS12390 21a6b59ae4e163ed8c6880fb35d21056 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 5.3E-31 T 11-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS12390 21a6b59ae4e163ed8c6880fb35d21056 333 Gene3D G3DSA:3.30.360.10 161 315 1.3E-69 T 11-11-2016 AUP74_RS00300 3835344d2c00510977fe8d05ca660379 332 SUPERFAMILY SSF53697 6 329 1.21E-62 T 11-11-2016 AUP74_RS00300 3835344d2c00510977fe8d05ca660379 332 Gene3D G3DSA:3.40.50.10490 5 172 2.2E-26 T 11-11-2016 AUP74_RS00300 3835344d2c00510977fe8d05ca660379 332 Gene3D G3DSA:3.40.50.10490 179 332 8.7E-29 T 11-11-2016 AUP74_RS00300 3835344d2c00510977fe8d05ca660379 332 Pfam PF01380 SIS domain 43 164 8.3E-17 T 11-11-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 AUP74_RS00300 3835344d2c00510977fe8d05ca660379 332 Pfam PF01380 SIS domain 199 265 1.8E-7 T 11-11-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 AUP74_RS06870 adb5d28f576013a44ca26fbb5c5cd3d3 87 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 5 83 25.801 T 11-11-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS06870 adb5d28f576013a44ca26fbb5c5cd3d3 87 ProSitePatterns PS00056 Ribosomal protein S17 signature. 58 70 - T 11-11-2016 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06870 adb5d28f576013a44ca26fbb5c5cd3d3 87 Pfam PF00366 Ribosomal protein S17 12 77 6.3E-32 T 11-11-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS06870 adb5d28f576013a44ca26fbb5c5cd3d3 87 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 7 77 2.0E-37 T 11-11-2016 IPR019984 Ribosomal protein S17, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS06870 adb5d28f576013a44ca26fbb5c5cd3d3 87 PRINTS PR00973 Ribosomal protein S17 family signature 68 75 1.5E-11 T 11-11-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS06870 adb5d28f576013a44ca26fbb5c5cd3d3 87 PRINTS PR00973 Ribosomal protein S17 family signature 26 49 1.5E-11 T 11-11-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS06870 adb5d28f576013a44ca26fbb5c5cd3d3 87 PRINTS PR00973 Ribosomal protein S17 family signature 58 68 1.5E-11 T 11-11-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS06870 adb5d28f576013a44ca26fbb5c5cd3d3 87 SUPERFAMILY SSF50249 7 84 5.57E-32 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS06870 adb5d28f576013a44ca26fbb5c5cd3d3 87 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 8 77 6.0E-28 T 11-11-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS06870 adb5d28f576013a44ca26fbb5c5cd3d3 87 Gene3D G3DSA:2.40.50.140 7 84 3.9E-35 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS00305 09303badd9688339f43520e10abc071c 315 SUPERFAMILY SSF53067 121 290 1.94E-40 T 11-11-2016 AUP74_RS00305 09303badd9688339f43520e10abc071c 315 SUPERFAMILY SSF53067 9 118 2.81E-24 T 11-11-2016 AUP74_RS00305 09303badd9688339f43520e10abc071c 315 Gene3D G3DSA:3.30.420.40 10 84 2.8E-5 T 11-11-2016 AUP74_RS00305 09303badd9688339f43520e10abc071c 315 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 12 290 4.9E-34 T 11-11-2016 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 AUP74_RS12565 8e763a2e634c89d902b7e776c893a3eb 164 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 82 4.2E-8 T 11-11-2016 IPR013078 Histidine phosphatase superfamily, clade-1 AUP74_RS12565 8e763a2e634c89d902b7e776c893a3eb 164 Gene3D G3DSA:3.40.50.1240 2 161 6.1E-45 T 11-11-2016 IPR029033 Histidine phosphatase superfamily AUP74_RS12565 8e763a2e634c89d902b7e776c893a3eb 164 SUPERFAMILY SSF53254 2 148 1.81E-23 T 11-11-2016 IPR029033 Histidine phosphatase superfamily AUP74_RS04470 4d72c124318ecb3df81441d2c25f1f76 509 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 6 507 1.1E-181 T 11-11-2016 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 AUP74_RS04470 4d72c124318ecb3df81441d2c25f1f76 509 Pfam PF11638 DnaA N-terminal domain 3 66 2.3E-18 T 11-11-2016 IPR024633 DnaA N-terminal domain AUP74_RS04470 4d72c124318ecb3df81441d2c25f1f76 509 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 207 227 6.8E-54 T 11-11-2016 IPR020591 Chromosomal replication control, initiator DnaA-like AUP74_RS04470 4d72c124318ecb3df81441d2c25f1f76 509 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 271 285 6.8E-54 T 11-11-2016 IPR020591 Chromosomal replication control, initiator DnaA-like AUP74_RS04470 4d72c124318ecb3df81441d2c25f1f76 509 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 467 486 6.8E-54 T 11-11-2016 IPR020591 Chromosomal replication control, initiator DnaA-like AUP74_RS04470 4d72c124318ecb3df81441d2c25f1f76 509 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 239 253 6.8E-54 T 11-11-2016 IPR020591 Chromosomal replication control, initiator DnaA-like AUP74_RS04470 4d72c124318ecb3df81441d2c25f1f76 509 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 305 332 6.8E-54 T 11-11-2016 IPR020591 Chromosomal replication control, initiator DnaA-like AUP74_RS04470 4d72c124318ecb3df81441d2c25f1f76 509 SMART SM00382 206 336 1.7E-6 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS04470 4d72c124318ecb3df81441d2c25f1f76 509 Gene3D G3DSA:1.10.8.60 340 407 2.1E-27 T 11-11-2016 AUP74_RS04470 4d72c124318ecb3df81441d2c25f1f76 509 Gene3D G3DSA:3.40.50.300 170 338 1.6E-61 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04470 4d72c124318ecb3df81441d2c25f1f76 509 Gene3D G3DSA:1.10.1750.10 408 508 1.6E-41 T 11-11-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 AUP74_RS04470 4d72c124318ecb3df81441d2c25f1f76 509 SUPERFAMILY SSF52540 174 385 2.11E-44 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04470 4d72c124318ecb3df81441d2c25f1f76 509 ProSitePatterns PS01008 DnaA protein signature. 467 486 - T 11-11-2016 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 AUP74_RS04470 4d72c124318ecb3df81441d2c25f1f76 509 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 418 486 2.8E-32 T 11-11-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 AUP74_RS04470 4d72c124318ecb3df81441d2c25f1f76 509 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 3 508 34.047 T 11-11-2016 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 AUP74_RS04470 4d72c124318ecb3df81441d2c25f1f76 509 SMART SM00760 417 486 3.4E-44 T 11-11-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 AUP74_RS04470 4d72c124318ecb3df81441d2c25f1f76 509 SUPERFAMILY SSF48295 405 507 8.11E-38 T 11-11-2016 IPR010921 Trp repressor/replication initiator GO:0043565 AUP74_RS04470 4d72c124318ecb3df81441d2c25f1f76 509 Pfam PF00308 Bacterial dnaA protein 174 391 2.1E-96 T 11-11-2016 IPR013317 Chromosomal replication initiator protein DnaA AUP74_RS14045 c0d904f95b3030e30f343b8903c74d25 237 SUPERFAMILY SSF50891 97 228 5.69E-43 T 11-11-2016 IPR029000 Cyclophilin-like domain AUP74_RS14045 c0d904f95b3030e30f343b8903c74d25 237 Pfam PF02682 Allophanate hydrolase subunit 1 2 211 1.1E-64 T 11-11-2016 IPR003833 Carboxyltransferase domain, subdomain C and D AUP74_RS14045 c0d904f95b3030e30f343b8903c74d25 237 Gene3D G3DSA:3.30.1360.40 3 79 1.5E-14 T 11-11-2016 IPR024946 Arginine repressor C-terminal-like domain AUP74_RS14045 c0d904f95b3030e30f343b8903c74d25 237 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 8 220 7.3E-52 T 11-11-2016 IPR010016 KipI family AUP74_RS14045 c0d904f95b3030e30f343b8903c74d25 237 Gene3D G3DSA:2.40.100.10 97 232 9.4E-49 T 11-11-2016 IPR029000 Cyclophilin-like domain AUP74_RS14045 c0d904f95b3030e30f343b8903c74d25 237 SMART SM00796 2 211 1.0E-77 T 11-11-2016 IPR003833 Carboxyltransferase domain, subdomain C and D AUP74_RS14045 c0d904f95b3030e30f343b8903c74d25 237 SUPERFAMILY SSF160467 3 101 5.49E-15 T 11-11-2016 AUP74_RS06175 b78bb149e487746ac7d25f1c40ab98dd 161 Pfam PF03734 L,D-transpeptidase catalytic domain 26 159 4.5E-17 T 11-11-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 AUP74_RS06175 b78bb149e487746ac7d25f1c40ab98dd 161 Gene3D G3DSA:2.40.440.10 22 160 4.0E-20 T 11-11-2016 AUP74_RS06175 b78bb149e487746ac7d25f1c40ab98dd 161 SUPERFAMILY SSF141523 24 160 4.05E-25 T 11-11-2016 AUP74_RS03990 dd854b2693b75d05923cca23cdb65625 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 21.613 T 11-11-2016 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS03990 dd854b2693b75d05923cca23cdb65625 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 57 7.9E-28 T 11-11-2016 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS03990 dd854b2693b75d05923cca23cdb65625 78 SUPERFAMILY SSF143800 2 77 1.96E-30 T 11-11-2016 AUP74_RS03990 dd854b2693b75d05923cca23cdb65625 78 Pfam PF00830 Ribosomal L28 family 3 62 5.0E-26 T 11-11-2016 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS03990 dd854b2693b75d05923cca23cdb65625 78 Gene3D G3DSA:2.30.170.40 2 78 5.8E-36 T 11-11-2016 AUP74_RS11730 a90b94b9ef8c6ef1bcf15299b7d3eb8d 231 SMART SM00382 38 211 1.2E-9 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS11730 a90b94b9ef8c6ef1bcf15299b7d3eb8d 231 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AUP74_RS11730 a90b94b9ef8c6ef1bcf15299b7d3eb8d 231 Pfam PF00005 ABC transporter 29 160 7.6E-21 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AUP74_RS11730 a90b94b9ef8c6ef1bcf15299b7d3eb8d 231 Gene3D G3DSA:3.40.50.300 4 223 9.2E-44 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11730 a90b94b9ef8c6ef1bcf15299b7d3eb8d 231 SUPERFAMILY SSF52540 4 223 1.01E-39 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03955 587a0236d754508d423fa585cb4e7e83 158 Gene3D G3DSA:3.40.50.620 1 157 1.0E-53 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS03955 587a0236d754508d423fa585cb4e7e83 158 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 158 36.332 T 11-11-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 AUP74_RS03955 587a0236d754508d423fa585cb4e7e83 158 Pfam PF01467 Cytidylyltransferase-like 5 133 2.0E-18 T 11-11-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AUP74_RS03955 587a0236d754508d423fa585cb4e7e83 158 SUPERFAMILY SSF52374 1 156 1.15E-45 T 11-11-2016 AUP74_RS03955 587a0236d754508d423fa585cb4e7e83 158 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 63 8.2E-20 T 11-11-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AUP74_RS03955 587a0236d754508d423fa585cb4e7e83 158 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 4 157 1.7E-58 T 11-11-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 AUP74_RS03955 587a0236d754508d423fa585cb4e7e83 158 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 11 68 5.0E-4 T 11-11-2016 AUP74_RS03955 587a0236d754508d423fa585cb4e7e83 158 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 85 101 1.5E-49 T 11-11-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 AUP74_RS03955 587a0236d754508d423fa585cb4e7e83 158 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 1.5E-49 T 11-11-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 AUP74_RS03955 587a0236d754508d423fa585cb4e7e83 158 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 1.5E-49 T 11-11-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 AUP74_RS03955 587a0236d754508d423fa585cb4e7e83 158 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 49 73 1.5E-49 T 11-11-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 AUP74_RS03955 587a0236d754508d423fa585cb4e7e83 158 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 112 134 1.5E-49 T 11-11-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 AUP74_RS16150 80fcab603fd1ce1bd6c73aa31f22834e 179 SUPERFAMILY SSF55620 1 179 4.74E-77 T 11-11-2016 AUP74_RS16150 80fcab603fd1ce1bd6c73aa31f22834e 179 Gene3D G3DSA:3.30.1130.10 51 179 1.4E-61 T 11-11-2016 AUP74_RS16150 80fcab603fd1ce1bd6c73aa31f22834e 179 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 1 179 36.263 T 11-11-2016 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 AUP74_RS16150 80fcab603fd1ce1bd6c73aa31f22834e 179 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 1 179 7.6E-77 T 11-11-2016 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 AUP74_RS16150 80fcab603fd1ce1bd6c73aa31f22834e 179 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 58 74 - T 11-11-2016 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 AUP74_RS16150 80fcab603fd1ce1bd6c73aa31f22834e 179 Gene3D G3DSA:1.10.286.10 1 48 4.6E-20 T 11-11-2016 AUP74_RS16150 80fcab603fd1ce1bd6c73aa31f22834e 179 Pfam PF01227 GTP cyclohydrolase I 2 178 9.1E-76 T 11-11-2016 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 AUP74_RS02915 2762be656ec7679755475005208d3568 520 SUPERFAMILY SSF52743 94 491 1.52E-89 T 11-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AUP74_RS02915 2762be656ec7679755475005208d3568 520 Gene3D G3DSA:3.50.30.30 293 421 6.0E-35 T 11-11-2016 AUP74_RS02915 2762be656ec7679755475005208d3568 520 PRINTS PR00723 Subtilisin serine protease family (S8) signature 113 132 1.1E-17 T 11-11-2016 IPR015500 Peptidase S8, subtilisin-related AUP74_RS02915 2762be656ec7679755475005208d3568 520 PRINTS PR00723 Subtilisin serine protease family (S8) signature 151 164 1.1E-17 T 11-11-2016 IPR015500 Peptidase S8, subtilisin-related AUP74_RS02915 2762be656ec7679755475005208d3568 520 PRINTS PR00723 Subtilisin serine protease family (S8) signature 429 445 1.1E-17 T 11-11-2016 IPR015500 Peptidase S8, subtilisin-related AUP74_RS02915 2762be656ec7679755475005208d3568 520 Pfam PF02225 PA domain 329 408 1.5E-10 T 11-11-2016 IPR003137 PA domain AUP74_RS02915 2762be656ec7679755475005208d3568 520 Gene3D G3DSA:3.30.70.80 22 94 1.1E-15 T 11-11-2016 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 AUP74_RS02915 2762be656ec7679755475005208d3568 520 Gene3D G3DSA:3.40.50.200 424 491 3.0E-78 T 11-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AUP74_RS02915 2762be656ec7679755475005208d3568 520 Gene3D G3DSA:3.40.50.200 99 292 3.0E-78 T 11-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AUP74_RS02915 2762be656ec7679755475005208d3568 520 SUPERFAMILY SSF54897 27 91 1.25E-9 T 11-11-2016 IPR009020 Proteinase propeptide inhibitor AUP74_RS02915 2762be656ec7679755475005208d3568 520 Pfam PF00082 Subtilase family 405 480 3.6E-14 T 11-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AUP74_RS02915 2762be656ec7679755475005208d3568 520 Pfam PF00082 Subtilase family 117 303 2.7E-27 T 11-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AUP74_RS02915 2762be656ec7679755475005208d3568 520 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 430 440 - T 11-11-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site AUP74_RS02915 2762be656ec7679755475005208d3568 520 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 155 165 - T 11-11-2016 IPR022398 Peptidase S8, subtilisin, His-active site AUP74_RS08975 12f86258bb6baea708928bef8be51e3e 865 Pfam PF00593 TonB dependent receptor 556 827 2.1E-18 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS08975 12f86258bb6baea708928bef8be51e3e 865 Gene3D G3DSA:2.170.130.10 56 182 1.6E-28 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS08975 12f86258bb6baea708928bef8be51e3e 865 SUPERFAMILY SSF56935 689 858 9.89E-88 T 11-11-2016 AUP74_RS08975 12f86258bb6baea708928bef8be51e3e 865 SUPERFAMILY SSF56935 380 657 9.89E-88 T 11-11-2016 AUP74_RS08975 12f86258bb6baea708928bef8be51e3e 865 SUPERFAMILY SSF56935 40 318 9.89E-88 T 11-11-2016 AUP74_RS08975 12f86258bb6baea708928bef8be51e3e 865 Gene3D G3DSA:2.40.170.20 183 314 1.8E-70 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS08975 12f86258bb6baea708928bef8be51e3e 865 Gene3D G3DSA:2.40.170.20 375 865 1.8E-70 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS08975 12f86258bb6baea708928bef8be51e3e 865 Pfam PF07715 TonB-dependent Receptor Plug Domain 55 179 3.1E-18 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS03160 38660d535e8ace4e6f7d6ffe2795e6c8 478 Pfam PF00224 Pyruvate kinase, barrel domain 2 341 1.2E-115 T 11-11-2016 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AUP74_RS03160 38660d535e8ace4e6f7d6ffe2795e6c8 478 Pfam PF02887 Pyruvate kinase, alpha/beta domain 361 475 8.3E-27 T 11-11-2016 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AUP74_RS03160 38660d535e8ace4e6f7d6ffe2795e6c8 478 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 3 477 8.4E-153 T 11-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AUP74_RS03160 38660d535e8ace4e6f7d6ffe2795e6c8 478 SUPERFAMILY SSF52935 326 477 9.55E-34 T 11-11-2016 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AUP74_RS03160 38660d535e8ace4e6f7d6ffe2795e6c8 478 Gene3D G3DSA:2.40.33.10 74 168 9.8E-23 T 11-11-2016 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AUP74_RS03160 38660d535e8ace4e6f7d6ffe2795e6c8 478 SUPERFAMILY SSF50800 71 164 9.77E-21 T 11-11-2016 IPR011037 Pyruvate kinase-like, insert domain AUP74_RS03160 38660d535e8ace4e6f7d6ffe2795e6c8 478 ProSitePatterns PS00110 Pyruvate kinase active site signature. 215 227 - T 11-11-2016 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AUP74_RS03160 38660d535e8ace4e6f7d6ffe2795e6c8 478 Gene3D G3DSA:3.20.20.60 3 73 1.2E-90 T 11-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AUP74_RS03160 38660d535e8ace4e6f7d6ffe2795e6c8 478 Gene3D G3DSA:3.20.20.60 169 328 1.2E-90 T 11-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AUP74_RS03160 38660d535e8ace4e6f7d6ffe2795e6c8 478 Gene3D G3DSA:3.40.1380.20 329 478 2.5E-36 T 11-11-2016 IPR015794 Pyruvate kinase, alpha/beta GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AUP74_RS03160 38660d535e8ace4e6f7d6ffe2795e6c8 478 SUPERFAMILY SSF51621 168 345 2.62E-87 T 11-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AUP74_RS03160 38660d535e8ace4e6f7d6ffe2795e6c8 478 SUPERFAMILY SSF51621 2 76 2.62E-87 T 11-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AUP74_RS03160 38660d535e8ace4e6f7d6ffe2795e6c8 478 PRINTS PR01050 Pyruvate kinase family signature 247 271 4.0E-50 T 11-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AUP74_RS03160 38660d535e8ace4e6f7d6ffe2795e6c8 478 PRINTS PR01050 Pyruvate kinase family signature 60 76 4.0E-50 T 11-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AUP74_RS03160 38660d535e8ace4e6f7d6ffe2795e6c8 478 PRINTS PR01050 Pyruvate kinase family signature 272 296 4.0E-50 T 11-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AUP74_RS03160 38660d535e8ace4e6f7d6ffe2795e6c8 478 PRINTS PR01050 Pyruvate kinase family signature 316 332 4.0E-50 T 11-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AUP74_RS03160 38660d535e8ace4e6f7d6ffe2795e6c8 478 PRINTS PR01050 Pyruvate kinase family signature 187 201 4.0E-50 T 11-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AUP74_RS03160 38660d535e8ace4e6f7d6ffe2795e6c8 478 PRINTS PR01050 Pyruvate kinase family signature 220 246 4.0E-50 T 11-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AUP74_RS03160 38660d535e8ace4e6f7d6ffe2795e6c8 478 PRINTS PR01050 Pyruvate kinase family signature 297 315 4.0E-50 T 11-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AUP74_RS00380 0d404388dc8ca0e575d2bff5e63fb7a2 525 SUPERFAMILY SSF56317 224 490 3.01E-45 T 11-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AUP74_RS00380 0d404388dc8ca0e575d2bff5e63fb7a2 525 Pfam PF00795 Carbon-nitrogen hydrolase 227 480 9.4E-32 T 11-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AUP74_RS00380 0d404388dc8ca0e575d2bff5e63fb7a2 525 Gene3D G3DSA:3.60.110.10 218 476 9.2E-33 T 11-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AUP74_RS00380 0d404388dc8ca0e575d2bff5e63fb7a2 525 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 3 495 21.865 T 11-11-2016 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 AUP74_RS00380 0d404388dc8ca0e575d2bff5e63fb7a2 525 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 62 458 9.7E-96 T 11-11-2016 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 AUP74_RS01780 e8561e5d14b70aed9cf4c251b8736527 202 Pfam PF01914 MarC family integral membrane protein 3 199 7.2E-44 T 11-11-2016 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 AUP74_RS01780 e8561e5d14b70aed9cf4c251b8736527 202 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 3 196 3.4E-39 T 11-11-2016 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 AUP74_RS15910 856d6263c797420cc467b8113ec49723 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 7.0E-17 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS15910 856d6263c797420cc467b8113ec49723 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 7.0E-17 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS15910 856d6263c797420cc467b8113ec49723 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 7.0E-17 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS15910 856d6263c797420cc467b8113ec49723 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 7.0E-17 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS15910 856d6263c797420cc467b8113ec49723 231 SUPERFAMILY SSF51735 4 231 5.72E-77 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS15910 856d6263c797420cc467b8113ec49723 231 Pfam PF00106 short chain dehydrogenase 4 192 2.1E-32 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS15910 856d6263c797420cc467b8113ec49723 231 Gene3D G3DSA:3.40.50.720 4 231 1.2E-69 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS05070 bb6da4f8c9752ca43815241d95f13e79 253 SUPERFAMILY SSF89550 2 207 3.73E-11 T 11-11-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AUP74_RS05070 bb6da4f8c9752ca43815241d95f13e79 253 PIRSF PIRSF016557 1 251 2.8E-60 T 11-11-2016 IPR016667 Capsular polysaccharide synthesis, CpsB/CapC GO:0004725|GO:0030145 AUP74_RS05165 8ebdaafc2991ff3b242d50df9dcecf62 389 Pfam PF02638 Glycosyl hydrolase-like 10 34 317 2.4E-64 T 11-11-2016 IPR003790 Glycosyl hydrolase-like 10 AUP74_RS05165 8ebdaafc2991ff3b242d50df9dcecf62 389 SUPERFAMILY SSF51445 34 299 6.61E-38 T 11-11-2016 IPR017853 Glycoside hydrolase superfamily AUP74_RS05165 8ebdaafc2991ff3b242d50df9dcecf62 389 Gene3D G3DSA:3.20.20.80 106 303 9.5E-8 T 11-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 AUP74_RS07065 e0b8fe472510bf5773b4c4821974f49f 229 Pfam PF00691 OmpA family 119 206 1.8E-16 T 11-11-2016 IPR006665 OmpA-like domain AUP74_RS07065 e0b8fe472510bf5773b4c4821974f49f 229 Gene3D G3DSA:3.30.1330.60 104 220 3.3E-25 T 11-11-2016 IPR006665 OmpA-like domain AUP74_RS07065 e0b8fe472510bf5773b4c4821974f49f 229 PRINTS PR01021 OMPA domain signature 150 165 1.7E-5 T 11-11-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AUP74_RS07065 e0b8fe472510bf5773b4c4821974f49f 229 PRINTS PR01021 OMPA domain signature 165 181 1.7E-5 T 11-11-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AUP74_RS07065 e0b8fe472510bf5773b4c4821974f49f 229 SUPERFAMILY SSF103088 114 220 2.35E-24 T 11-11-2016 IPR006665 OmpA-like domain AUP74_RS08070 898be58d76880de67dd33b2e6f7f5fde 639 Gene3D G3DSA:1.10.8.60 334 407 9.2E-29 T 11-11-2016 AUP74_RS08070 898be58d76880de67dd33b2e6f7f5fde 639 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 190 322 2.4E-46 T 11-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 AUP74_RS08070 898be58d76880de67dd33b2e6f7f5fde 639 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 100 590 1.6E-234 T 11-11-2016 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 AUP74_RS08070 898be58d76880de67dd33b2e6f7f5fde 639 SMART SM00382 186 325 7.9E-25 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS08070 898be58d76880de67dd33b2e6f7f5fde 639 Pfam PF01434 Peptidase family M41 384 588 1.0E-78 T 11-11-2016 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 AUP74_RS08070 898be58d76880de67dd33b2e6f7f5fde 639 SUPERFAMILY SSF52540 146 393 2.32E-71 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS08070 898be58d76880de67dd33b2e6f7f5fde 639 SUPERFAMILY SSF140990 404 601 3.14E-74 T 11-11-2016 AUP74_RS08070 898be58d76880de67dd33b2e6f7f5fde 639 Pfam PF06480 FtsH Extracellular 6 89 4.7E-11 T 11-11-2016 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 AUP74_RS08070 898be58d76880de67dd33b2e6f7f5fde 639 Gene3D G3DSA:3.40.50.300 150 333 1.5E-63 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS08070 898be58d76880de67dd33b2e6f7f5fde 639 ProSitePatterns PS00674 AAA-protein family signature. 293 311 - T 11-11-2016 IPR003960 ATPase, AAA-type, conserved site GO:0005524 AUP74_RS08070 898be58d76880de67dd33b2e6f7f5fde 639 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 3 599 37.426 T 11-11-2016 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 AUP74_RS05085 62956d2a6ba0dbe772bc80390e4bbfe8 366 Gene3D G3DSA:3.10.180.10 5 149 2.1E-46 T 11-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AUP74_RS05085 62956d2a6ba0dbe772bc80390e4bbfe8 366 PIRSF PIRSF009283 1 355 2.2E-112 T 11-11-2016 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 AUP74_RS05085 62956d2a6ba0dbe772bc80390e4bbfe8 366 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 160 276 3.1E-19 T 11-11-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AUP74_RS05085 62956d2a6ba0dbe772bc80390e4bbfe8 366 SUPERFAMILY SSF54593 5 342 1.69E-84 T 11-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AUP74_RS05085 62956d2a6ba0dbe772bc80390e4bbfe8 366 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 13 354 6.5E-121 T 11-11-2016 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 AUP74_RS05085 62956d2a6ba0dbe772bc80390e4bbfe8 366 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 5 143 1.5E-69 T 11-11-2016 AUP74_RS05085 62956d2a6ba0dbe772bc80390e4bbfe8 366 Gene3D G3DSA:3.10.180.10 156 355 7.9E-68 T 11-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AUP74_RS16585 be7721d254e00ae1a13a3f697f1224d6 430 Gene3D G3DSA:1.10.230.10 282 375 3.9E-40 T 11-11-2016 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 AUP74_RS16585 be7721d254e00ae1a13a3f697f1224d6 430 Gene3D G3DSA:1.10.580.10 53 281 2.2E-100 T 11-11-2016 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 AUP74_RS16585 be7721d254e00ae1a13a3f697f1224d6 430 PRINTS PR00143 Citrate synthase signature 242 270 2.5E-54 T 11-11-2016 IPR002020 Citrate synthase GO:0046912 AUP74_RS16585 be7721d254e00ae1a13a3f697f1224d6 430 PRINTS PR00143 Citrate synthase signature 361 377 2.5E-54 T 11-11-2016 IPR002020 Citrate synthase GO:0046912 AUP74_RS16585 be7721d254e00ae1a13a3f697f1224d6 430 PRINTS PR00143 Citrate synthase signature 381 395 2.5E-54 T 11-11-2016 IPR002020 Citrate synthase GO:0046912 AUP74_RS16585 be7721d254e00ae1a13a3f697f1224d6 430 PRINTS PR00143 Citrate synthase signature 297 317 2.5E-54 T 11-11-2016 IPR002020 Citrate synthase GO:0046912 AUP74_RS16585 be7721d254e00ae1a13a3f697f1224d6 430 PRINTS PR00143 Citrate synthase signature 166 179 2.5E-54 T 11-11-2016 IPR002020 Citrate synthase GO:0046912 AUP74_RS16585 be7721d254e00ae1a13a3f697f1224d6 430 PRINTS PR00143 Citrate synthase signature 220 235 2.5E-54 T 11-11-2016 IPR002020 Citrate synthase GO:0046912 AUP74_RS16585 be7721d254e00ae1a13a3f697f1224d6 430 PIRSF PIRSF001369 39 430 2.3E-173 T 11-11-2016 IPR024176 Citrate synthase, bacterial-type AUP74_RS16585 be7721d254e00ae1a13a3f697f1224d6 430 SUPERFAMILY SSF48256 15 429 3.27E-168 T 11-11-2016 IPR002020 Citrate synthase GO:0046912 AUP74_RS16585 be7721d254e00ae1a13a3f697f1224d6 430 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 16 423 3.7E-229 T 11-11-2016 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 AUP74_RS16585 be7721d254e00ae1a13a3f697f1224d6 430 Pfam PF00285 Citrate synthase, C-terminal domain 47 412 8.2E-135 T 11-11-2016 IPR002020 Citrate synthase GO:0046912 AUP74_RS16585 be7721d254e00ae1a13a3f697f1224d6 430 ProSitePatterns PS00480 Citrate synthase signature. 304 316 - T 11-11-2016 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 AUP74_RS16910 d24e9cfb956bb3b0c6aef769cea223be 420 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 417 5.8E-174 T 11-11-2016 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AUP74_RS16910 d24e9cfb956bb3b0c6aef769cea223be 420 Gene3D G3DSA:3.65.10.10 21 220 7.0E-71 T 11-11-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 AUP74_RS16910 d24e9cfb956bb3b0c6aef769cea223be 420 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 418 45.937 T 11-11-2016 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AUP74_RS16910 d24e9cfb956bb3b0c6aef769cea223be 420 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 408 5.2E-107 T 11-11-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 AUP74_RS16910 d24e9cfb956bb3b0c6aef769cea223be 420 SUPERFAMILY SSF55205 1 418 2.13E-141 T 11-11-2016 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 AUP74_RS16910 d24e9cfb956bb3b0c6aef769cea223be 420 Gene3D G3DSA:3.65.10.10 221 417 1.6E-55 T 11-11-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 AUP74_RS04500 1d804e07ba09f14575a5165711d26cca 722 Pfam PF07715 TonB-dependent Receptor Plug Domain 43 152 5.6E-15 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS04500 1d804e07ba09f14575a5165711d26cca 722 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 705 722 - T 11-11-2016 IPR010917 TonB-dependent receptor, conserved site AUP74_RS04500 1d804e07ba09f14575a5165711d26cca 722 Gene3D G3DSA:2.170.130.10 23 152 1.6E-19 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS04500 1d804e07ba09f14575a5165711d26cca 722 Gene3D G3DSA:2.40.170.20 153 722 2.4E-83 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS04500 1d804e07ba09f14575a5165711d26cca 722 SUPERFAMILY SSF56935 23 722 1.02E-97 T 11-11-2016 AUP74_RS04500 1d804e07ba09f14575a5165711d26cca 722 Pfam PF00593 TonB dependent receptor 476 720 2.0E-24 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS15830 e95bdd4d8cf0876b76990b1eff58132c 92 SUPERFAMILY SSF51182 15 89 1.13E-12 T 11-11-2016 IPR011051 RmlC-like cupin domain AUP74_RS15830 e95bdd4d8cf0876b76990b1eff58132c 92 Gene3D G3DSA:2.60.120.10 16 88 6.1E-11 T 11-11-2016 IPR014710 RmlC-like jelly roll fold AUP74_RS15830 e95bdd4d8cf0876b76990b1eff58132c 92 Pfam PF07883 Cupin domain 29 87 2.7E-7 T 11-11-2016 IPR013096 Cupin 2, conserved barrel AUP74_RS16280 150195f6eed3dfb06c023d23c1e868ce 391 Gene3D G3DSA:2.115.10.20 23 364 4.3E-86 T 11-11-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain AUP74_RS16280 150195f6eed3dfb06c023d23c1e868ce 391 Hamap MF_00928 4-O-beta-D-mannosyl-D-glucose phosphorylase. 3 387 69.678 T 11-11-2016 IPR028583 4-O-beta-D-mannosyl-D-glucose phosphorylase MetaCyc: PWY-7456 AUP74_RS16280 150195f6eed3dfb06c023d23c1e868ce 391 Pfam PF04041 beta-1,4-mannooligosaccharide phosphorylase 70 360 2.6E-20 T 11-11-2016 IPR007184 Mannoside phosphorylase AUP74_RS16280 150195f6eed3dfb06c023d23c1e868ce 391 SUPERFAMILY SSF75005 47 369 3.44E-74 T 11-11-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain AUP74_RS16280 150195f6eed3dfb06c023d23c1e868ce 391 PIRSF PIRSF016202 20 365 2.4E-83 T 11-11-2016 IPR007184 Mannoside phosphorylase AUP74_RS08570 6ac62e409851254caf2064a8c75474b0 1156 SUPERFAMILY SSF47384 764 850 2.75E-11 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS08570 6ac62e409851254caf2064a8c75474b0 1156 SUPERFAMILY SSF52172 1026 1146 4.13E-21 T 11-11-2016 IPR011006 CheY-like superfamily AUP74_RS08570 6ac62e409851254caf2064a8c75474b0 1156 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 894 1002 9.3E-20 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS08570 6ac62e409851254caf2064a8c75474b0 1156 SMART SM00388 781 849 1.2E-7 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS08570 6ac62e409851254caf2064a8c75474b0 1156 SMART SM00448 1027 1139 2.6E-13 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS08570 6ac62e409851254caf2064a8c75474b0 1156 SUPERFAMILY SSF55785 626 748 4.19E-12 T 11-11-2016 IPR000014 PAS domain AUP74_RS08570 6ac62e409851254caf2064a8c75474b0 1156 SMART SM00387 893 1004 1.8E-28 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS08570 6ac62e409851254caf2064a8c75474b0 1156 Gene3D G3DSA:1.10.287.130 773 845 5.2E-4 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS08570 6ac62e409851254caf2064a8c75474b0 1156 Pfam PF00072 Response regulator receiver domain 1029 1139 6.7E-11 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS08570 6ac62e409851254caf2064a8c75474b0 1156 PRINTS PR00344 Bacterial sensor protein C-terminal signature 964 982 4.6E-12 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS08570 6ac62e409851254caf2064a8c75474b0 1156 PRINTS PR00344 Bacterial sensor protein C-terminal signature 929 943 4.6E-12 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS08570 6ac62e409851254caf2064a8c75474b0 1156 PRINTS PR00344 Bacterial sensor protein C-terminal signature 947 957 4.6E-12 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS08570 6ac62e409851254caf2064a8c75474b0 1156 PRINTS PR00344 Bacterial sensor protein C-terminal signature 988 1001 4.6E-12 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS08570 6ac62e409851254caf2064a8c75474b0 1156 SUPERFAMILY SSF55874 840 1002 1.24E-38 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS08570 6ac62e409851254caf2064a8c75474b0 1156 Gene3D G3DSA:3.40.50.2300 1025 1145 6.6E-20 T 11-11-2016 AUP74_RS08570 6ac62e409851254caf2064a8c75474b0 1156 Gene3D G3DSA:3.30.450.20 626 749 8.5E-17 T 11-11-2016 AUP74_RS08570 6ac62e409851254caf2064a8c75474b0 1156 Pfam PF12860 PAS fold 639 753 7.7E-43 T 11-11-2016 AUP74_RS08570 6ac62e409851254caf2064a8c75474b0 1156 Gene3D G3DSA:3.30.565.10 850 1006 4.2E-39 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS08570 6ac62e409851254caf2064a8c75474b0 1156 Pfam PF00512 His Kinase A (phospho-acceptor) domain 781 849 9.8E-7 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS09820 afdcbfc065b316cb83c1ef1c8d353a27 349 Gene3D G3DSA:3.90.650.10 173 342 3.6E-69 T 11-11-2016 IPR010918 AIR synthase-related protein, C-terminal domain AUP74_RS09820 afdcbfc065b316cb83c1ef1c8d353a27 349 Pfam PF00586 AIR synthase related protein, N-terminal domain 61 166 1.1E-14 T 11-11-2016 IPR016188 PurM-like, N-terminal domain AUP74_RS09820 afdcbfc065b316cb83c1ef1c8d353a27 349 SUPERFAMILY SSF56042 173 339 1.5E-62 T 11-11-2016 IPR010918 AIR synthase-related protein, C-terminal domain AUP74_RS09820 afdcbfc065b316cb83c1ef1c8d353a27 349 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 9 335 5.4E-146 T 11-11-2016 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AUP74_RS09820 afdcbfc065b316cb83c1ef1c8d353a27 349 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 9 346 47.887 T 11-11-2016 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AUP74_RS09820 afdcbfc065b316cb83c1ef1c8d353a27 349 Gene3D G3DSA:3.30.1330.10 24 172 1.1E-62 T 11-11-2016 IPR016188 PurM-like, N-terminal domain AUP74_RS09820 afdcbfc065b316cb83c1ef1c8d353a27 349 SUPERFAMILY SSF55326 9 172 9.87E-53 T 11-11-2016 AUP74_RS09820 afdcbfc065b316cb83c1ef1c8d353a27 349 Pfam PF02769 AIR synthase related protein, C-terminal domain 178 338 2.3E-37 T 11-11-2016 IPR010918 AIR synthase-related protein, C-terminal domain AUP74_RS07935 011372e73e640b49be996631c48171c8 555 Pfam PF02463 RecF/RecN/SMC N terminal domain 4 512 8.4E-19 T 11-11-2016 IPR003395 RecF/RecN/SMC, N-terminal AUP74_RS07935 011372e73e640b49be996631c48171c8 555 Gene3D G3DSA:3.40.50.300 1 206 5.8E-67 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS07935 011372e73e640b49be996631c48171c8 555 PIRSF PIRSF003128 1 555 1.1E-157 T 11-11-2016 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 AUP74_RS07935 011372e73e640b49be996631c48171c8 555 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 553 3.0E-150 T 11-11-2016 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 AUP74_RS07935 011372e73e640b49be996631c48171c8 555 SUPERFAMILY SSF52540 349 513 6.09E-64 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS07935 011372e73e640b49be996631c48171c8 555 SUPERFAMILY SSF52540 1 199 6.09E-64 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS07935 011372e73e640b49be996631c48171c8 555 SUPERFAMILY SSF52540 286 321 6.09E-64 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS07935 011372e73e640b49be996631c48171c8 555 Gene3D G3DSA:3.40.50.300 397 508 1.4E-5 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04605 0e6c7bf4ee692764cdfe93f06040b22d 274 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 2 270 33.113 T 11-11-2016 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 AUP74_RS04605 0e6c7bf4ee692764cdfe93f06040b22d 274 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 119 192 8.7E-9 T 11-11-2016 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase AUP74_RS04605 0e6c7bf4ee692764cdfe93f06040b22d 274 SUPERFAMILY SSF51735 103 267 1.64E-41 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS04605 0e6c7bf4ee692764cdfe93f06040b22d 274 Gene3D G3DSA:3.40.192.10 2 109 3.1E-39 T 11-11-2016 AUP74_RS04605 0e6c7bf4ee692764cdfe93f06040b22d 274 SUPERFAMILY SSF53223 3 102 2.07E-32 T 11-11-2016 AUP74_RS04605 0e6c7bf4ee692764cdfe93f06040b22d 274 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 7 89 2.9E-26 T 11-11-2016 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 AUP74_RS04605 0e6c7bf4ee692764cdfe93f06040b22d 274 Gene3D G3DSA:3.40.50.720 110 245 4.1E-46 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS04605 0e6c7bf4ee692764cdfe93f06040b22d 274 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 4 270 1.8E-83 T 11-11-2016 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 AUP74_RS04110 874647f8aacdeba8a49c068d0d71bce2 86 Pfam PF04226 Transglycosylase associated protein 33 83 1.7E-13 T 11-11-2016 IPR007341 Transglycosylase-associated protein GO:0016021 AUP74_RS14155 d13b547547855f26a7f33a6be2ea2dd5 534 SUPERFAMILY SSF52518 358 529 3.42E-43 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS14155 d13b547547855f26a7f33a6be2ea2dd5 534 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 172 1.0E-54 T 11-11-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 AUP74_RS14155 d13b547547855f26a7f33a6be2ea2dd5 534 Gene3D G3DSA:3.40.50.1220 185 371 3.0E-44 T 11-11-2016 IPR029035 DHS-like NAD/FAD-binding domain AUP74_RS14155 d13b547547855f26a7f33a6be2ea2dd5 534 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 417 436 - T 11-11-2016 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 AUP74_RS14155 d13b547547855f26a7f33a6be2ea2dd5 534 Gene3D G3DSA:3.40.50.970 2 179 4.6E-60 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS14155 d13b547547855f26a7f33a6be2ea2dd5 534 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 193 323 1.6E-29 T 11-11-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 AUP74_RS14155 d13b547547855f26a7f33a6be2ea2dd5 534 SUPERFAMILY SSF52518 2 179 2.07E-53 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS14155 d13b547547855f26a7f33a6be2ea2dd5 534 Gene3D G3DSA:3.40.50.970 372 529 4.0E-44 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS14155 d13b547547855f26a7f33a6be2ea2dd5 534 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 387 527 1.9E-29 T 11-11-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AUP74_RS14155 d13b547547855f26a7f33a6be2ea2dd5 534 SUPERFAMILY SSF52467 157 345 4.09E-40 T 11-11-2016 IPR029035 DHS-like NAD/FAD-binding domain AUP74_RS05255 a5ab15363e269ff6bf70dd7dcab693ff 561 SUPERFAMILY SSF52540 222 549 3.44E-41 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05255 a5ab15363e269ff6bf70dd7dcab693ff 561 Gene3D G3DSA:3.40.50.300 221 403 4.5E-21 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05255 a5ab15363e269ff6bf70dd7dcab693ff 561 Gene3D G3DSA:3.40.50.300 404 551 9.0E-11 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05255 a5ab15363e269ff6bf70dd7dcab693ff 561 Pfam PF08378 Nuclease-related domain 19 125 1.2E-9 T 11-11-2016 IPR011528 Nuclease-related domain, NERD AUP74_RS05255 a5ab15363e269ff6bf70dd7dcab693ff 561 Pfam PF13538 UvrD-like helicase C-terminal domain 499 544 1.3E-6 T 11-11-2016 IPR027785 UvrD-like helicase C-terminal domain AUP74_RS05255 a5ab15363e269ff6bf70dd7dcab693ff 561 Pfam PF13245 Part of AAA domain 239 290 6.4E-6 T 11-11-2016 AUP74_RS12180 f6dc68ff611891ddedc152df33df69f7 810 SMART SM00849 560 753 5.3E-9 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS12180 f6dc68ff611891ddedc152df33df69f7 810 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 252 450 6.2E-19 T 11-11-2016 IPR004477 ComEC/Rec2-related protein AUP74_RS12180 f6dc68ff611891ddedc152df33df69f7 810 Gene3D G3DSA:3.60.15.10 550 772 4.4E-26 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS12180 f6dc68ff611891ddedc152df33df69f7 810 Pfam PF03772 Competence protein 231 516 1.4E-49 T 11-11-2016 IPR004477 ComEC/Rec2-related protein AUP74_RS12180 f6dc68ff611891ddedc152df33df69f7 810 Pfam PF13567 Domain of unknown function (DUF4131) 14 194 5.3E-26 T 11-11-2016 IPR025405 Domain of unknown function DUF4131 AUP74_RS12180 f6dc68ff611891ddedc152df33df69f7 810 SUPERFAMILY SSF56281 552 787 7.47E-43 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS12180 f6dc68ff611891ddedc152df33df69f7 810 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 150 782 9.9E-93 T 11-11-2016 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 AUP74_RS12180 f6dc68ff611891ddedc152df33df69f7 810 Pfam PF00753 Metallo-beta-lactamase superfamily 557 740 1.8E-13 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS01855 1e2010af6d2d381373ac436f541c3cc4 265 Pfam PF03649 Uncharacterised protein family (UPF0014) 8 251 2.1E-84 T 11-11-2016 IPR005226 UPF0014 family AUP74_RS01855 1e2010af6d2d381373ac436f541c3cc4 265 TIGRFAM TIGR00245 TIGR00245: TIGR00245 family protein 7 256 9.2E-57 T 11-11-2016 IPR005226 UPF0014 family AUP74_RS00250 b2f4c9d6d187e185239826ddcb569ab3 479 Gene3D G3DSA:3.40.1380.20 329 478 4.1E-29 T 11-11-2016 IPR015794 Pyruvate kinase, alpha/beta GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AUP74_RS00250 b2f4c9d6d187e185239826ddcb569ab3 479 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 3 478 3.2E-157 T 11-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AUP74_RS00250 b2f4c9d6d187e185239826ddcb569ab3 479 SUPERFAMILY SSF51621 157 342 2.27E-88 T 11-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AUP74_RS00250 b2f4c9d6d187e185239826ddcb569ab3 479 SUPERFAMILY SSF51621 2 75 2.27E-88 T 11-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AUP74_RS00250 b2f4c9d6d187e185239826ddcb569ab3 479 Pfam PF00224 Pyruvate kinase, barrel domain 3 345 8.3E-126 T 11-11-2016 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AUP74_RS00250 b2f4c9d6d187e185239826ddcb569ab3 479 Gene3D G3DSA:2.40.33.10 74 169 1.4E-28 T 11-11-2016 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AUP74_RS00250 b2f4c9d6d187e185239826ddcb569ab3 479 SUPERFAMILY SSF50800 71 166 1.31E-24 T 11-11-2016 IPR011037 Pyruvate kinase-like, insert domain AUP74_RS00250 b2f4c9d6d187e185239826ddcb569ab3 479 SUPERFAMILY SSF52935 327 478 3.53E-26 T 11-11-2016 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AUP74_RS00250 b2f4c9d6d187e185239826ddcb569ab3 479 Gene3D G3DSA:3.20.20.60 170 328 4.4E-93 T 11-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AUP74_RS00250 b2f4c9d6d187e185239826ddcb569ab3 479 Gene3D G3DSA:3.20.20.60 3 73 4.4E-93 T 11-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AUP74_RS00250 b2f4c9d6d187e185239826ddcb569ab3 479 Pfam PF02887 Pyruvate kinase, alpha/beta domain 362 475 8.6E-22 T 11-11-2016 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AUP74_RS00250 b2f4c9d6d187e185239826ddcb569ab3 479 ProSitePatterns PS00110 Pyruvate kinase active site signature. 215 227 - T 11-11-2016 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AUP74_RS00250 b2f4c9d6d187e185239826ddcb569ab3 479 PRINTS PR01050 Pyruvate kinase family signature 247 271 1.5E-52 T 11-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AUP74_RS00250 b2f4c9d6d187e185239826ddcb569ab3 479 PRINTS PR01050 Pyruvate kinase family signature 187 201 1.5E-52 T 11-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AUP74_RS00250 b2f4c9d6d187e185239826ddcb569ab3 479 PRINTS PR01050 Pyruvate kinase family signature 60 76 1.5E-52 T 11-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AUP74_RS00250 b2f4c9d6d187e185239826ddcb569ab3 479 PRINTS PR01050 Pyruvate kinase family signature 316 332 1.5E-52 T 11-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AUP74_RS00250 b2f4c9d6d187e185239826ddcb569ab3 479 PRINTS PR01050 Pyruvate kinase family signature 297 315 1.5E-52 T 11-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AUP74_RS00250 b2f4c9d6d187e185239826ddcb569ab3 479 PRINTS PR01050 Pyruvate kinase family signature 220 246 1.5E-52 T 11-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AUP74_RS00250 b2f4c9d6d187e185239826ddcb569ab3 479 PRINTS PR01050 Pyruvate kinase family signature 272 296 1.5E-52 T 11-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AUP74_RS10625 16dda8f01a10234f926bd77ff32bd8d5 276 PIRSF PIRSF004750 2 276 1.2E-106 T 11-11-2016 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 AUP74_RS10625 16dda8f01a10234f926bd77ff32bd8d5 276 SUPERFAMILY SSF55620 180 268 1.85E-8 T 11-11-2016 AUP74_RS10625 16dda8f01a10234f926bd77ff32bd8d5 276 Pfam PF14489 QueF-like protein 190 263 6.3E-22 T 11-11-2016 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 AUP74_RS10625 16dda8f01a10234f926bd77ff32bd8d5 276 Gene3D G3DSA:3.30.1130.10 141 263 1.9E-45 T 11-11-2016 AUP74_RS10625 16dda8f01a10234f926bd77ff32bd8d5 276 Gene3D G3DSA:3.30.1130.10 17 130 2.6E-35 T 11-11-2016 AUP74_RS10625 16dda8f01a10234f926bd77ff32bd8d5 276 Hamap MF_00817 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 276 127.511 T 11-11-2016 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 AUP74_RS10625 16dda8f01a10234f926bd77ff32bd8d5 276 Pfam PF14819 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term 17 127 7.3E-43 T 11-11-2016 IPR029139 NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 AUP74_RS10625 16dda8f01a10234f926bd77ff32bd8d5 276 TIGRFAM TIGR03138 QueF: queuine synthase 8 267 3.4E-112 T 11-11-2016 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 AUP74_RS12540 4ae8db783d011b8637d1cb3bdb42fc84 546 Gene3D G3DSA:3.40.50.1220 178 330 9.7E-40 T 11-11-2016 IPR029035 DHS-like NAD/FAD-binding domain AUP74_RS12540 4ae8db783d011b8637d1cb3bdb42fc84 546 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 165 1.4E-51 T 11-11-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 AUP74_RS12540 4ae8db783d011b8637d1cb3bdb42fc84 546 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 186 319 3.9E-30 T 11-11-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 AUP74_RS12540 4ae8db783d011b8637d1cb3bdb42fc84 546 Gene3D G3DSA:3.40.50.970 335 532 8.7E-57 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS12540 4ae8db783d011b8637d1cb3bdb42fc84 546 Gene3D G3DSA:3.40.50.970 1 177 6.3E-64 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS12540 4ae8db783d011b8637d1cb3bdb42fc84 546 SUPERFAMILY SSF52518 355 533 1.75E-57 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS12540 4ae8db783d011b8637d1cb3bdb42fc84 546 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 415 434 - T 11-11-2016 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 AUP74_RS12540 4ae8db783d011b8637d1cb3bdb42fc84 546 SUPERFAMILY SSF52518 1 179 6.45E-47 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS12540 4ae8db783d011b8637d1cb3bdb42fc84 546 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 378 524 1.1E-39 T 11-11-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AUP74_RS12540 4ae8db783d011b8637d1cb3bdb42fc84 546 SUPERFAMILY SSF52467 178 362 3.27E-43 T 11-11-2016 IPR029035 DHS-like NAD/FAD-binding domain AUP74_RS05140 691142e731cd7cb3ba4260b4e0cf3572 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 264 1.6E-18 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AUP74_RS05140 691142e731cd7cb3ba4260b4e0cf3572 275 SUPERFAMILY SSF161098 3 275 5.14E-75 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AUP74_RS05140 691142e731cd7cb3ba4260b4e0cf3572 275 Gene3D G3DSA:1.10.3720.10 2 262 6.3E-66 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AUP74_RS14955 74d45aafad36585304aa5ea38d9c4dc9 425 TIGRFAM TIGR02069 cyanophycinase: cyanophycinase 36 316 2.2E-52 T 11-11-2016 IPR011811 Peptidase S51, cyanophycinase GO:0016787|GO:0044260 MetaCyc: PWY-7052 AUP74_RS14955 74d45aafad36585304aa5ea38d9c4dc9 425 SUPERFAMILY SSF52317 53 287 6.87E-15 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS14955 74d45aafad36585304aa5ea38d9c4dc9 425 Gene3D G3DSA:3.40.50.880 41 289 1.5E-19 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS14955 74d45aafad36585304aa5ea38d9c4dc9 425 Pfam PF03575 Peptidase family S51 38 269 5.5E-10 T 11-11-2016 IPR005320 Peptidase S51 GO:0006508|GO:0008236 AUP74_RS04665 c6bcddb6f2919959b3e6cb01d4b39f65 89 TIGRFAM TIGR02443 TIGR02443: conserved hypothetical protein 10 51 3.6E-15 T 11-11-2016 IPR012658 Conserved hypothetical protein CHP02443 AUP74_RS04665 c6bcddb6f2919959b3e6cb01d4b39f65 89 Pfam PF09526 Probable metal-binding protein (DUF2387) 10 75 2.2E-24 T 11-11-2016 IPR012658 Conserved hypothetical protein CHP02443 AUP74_RS01110 0d432970f854744f32d8dd137a48f0b5 116 Pfam PF03334 Na+/H+ antiporter subunit 11 90 2.8E-24 T 11-11-2016 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 AUP74_RS01110 0d432970f854744f32d8dd137a48f0b5 116 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 11 100 4.8E-23 T 11-11-2016 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 AUP74_RS11190 dca0a00df110dbfc1925584a9fa53aa8 391 SUPERFAMILY SSF53901 266 390 1.04E-40 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS11190 dca0a00df110dbfc1925584a9fa53aa8 391 Pfam PF02803 Thiolase, C-terminal domain 266 390 1.2E-46 T 11-11-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 AUP74_RS11190 dca0a00df110dbfc1925584a9fa53aa8 391 PIRSF PIRSF000429 2 391 1.7E-133 T 11-11-2016 IPR002155 Thiolase GO:0008152|GO:0016747 AUP74_RS11190 dca0a00df110dbfc1925584a9fa53aa8 391 SUPERFAMILY SSF53901 4 262 1.92E-76 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS11190 dca0a00df110dbfc1925584a9fa53aa8 391 Pfam PF00108 Thiolase, N-terminal domain 9 257 3.4E-74 T 11-11-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 AUP74_RS11190 dca0a00df110dbfc1925584a9fa53aa8 391 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 10 389 1.9E-137 T 11-11-2016 IPR002155 Thiolase GO:0008152|GO:0016747 AUP74_RS11190 dca0a00df110dbfc1925584a9fa53aa8 391 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 91 109 - T 11-11-2016 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 AUP74_RS11190 dca0a00df110dbfc1925584a9fa53aa8 391 Gene3D G3DSA:3.40.47.10 188 271 3.8E-62 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS11190 dca0a00df110dbfc1925584a9fa53aa8 391 Gene3D G3DSA:3.40.47.10 7 130 3.8E-62 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS11190 dca0a00df110dbfc1925584a9fa53aa8 391 ProSitePatterns PS00737 Thiolases signature 2. 337 353 - T 11-11-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 AUP74_RS11190 dca0a00df110dbfc1925584a9fa53aa8 391 TIGRFAM TIGR02445 fadA: acetyl-CoA C-acyltransferase FadA 7 391 4.1E-188 T 11-11-2016 IPR012805 Acetyl-CoA C-acyltransferase FadA GO:0003988|GO:0005737|GO:0006631|GO:0016042 KEGG: 00062+2.3.1.16|KEGG: 00071+2.3.1.16|KEGG: 00280+2.3.1.16|KEGG: 00281+2.3.1.16|KEGG: 00362+2.3.1.16|KEGG: 00592+2.3.1.16|KEGG: 00642+2.3.1.16|MetaCyc: PWY-5136|MetaCyc: PWY-6435|MetaCyc: PWY-6863|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-7094|MetaCyc: PWY-7288|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7339|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7726 AUP74_RS11190 dca0a00df110dbfc1925584a9fa53aa8 391 Gene3D G3DSA:3.40.47.10 146 187 1.1E-54 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS11190 dca0a00df110dbfc1925584a9fa53aa8 391 Gene3D G3DSA:3.40.47.10 272 390 1.1E-54 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS01555 81bcf0b3d21e7183a77dcda80306148a 220 Gene3D G3DSA:2.40.30.20 5 104 4.3E-31 T 11-11-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 AUP74_RS01555 81bcf0b3d21e7183a77dcda80306148a 220 Gene3D G3DSA:2.40.30.20 105 194 5.3E-31 T 11-11-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 AUP74_RS01555 81bcf0b3d21e7183a77dcda80306148a 220 SUPERFAMILY SSF63380 93 194 3.4E-31 T 11-11-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 AUP74_RS01555 81bcf0b3d21e7183a77dcda80306148a 220 PIRSF PIRSF000498 1 212 2.1E-76 T 11-11-2016 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AUP74_RS01555 81bcf0b3d21e7183a77dcda80306148a 220 Pfam PF00677 Lumazine binding domain 100 184 3.5E-21 T 11-11-2016 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AUP74_RS01555 81bcf0b3d21e7183a77dcda80306148a 220 Pfam PF00677 Lumazine binding domain 3 87 6.7E-22 T 11-11-2016 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AUP74_RS01555 81bcf0b3d21e7183a77dcda80306148a 220 SUPERFAMILY SSF63380 1 89 3.06E-26 T 11-11-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 AUP74_RS01555 81bcf0b3d21e7183a77dcda80306148a 220 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 198 1.4E-64 T 11-11-2016 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AUP74_RS06345 4acab3a0ab4d356f57d598fc81574fcc 304 Gene3D G3DSA:3.40.50.1820 68 304 1.6E-28 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS06345 4acab3a0ab4d356f57d598fc81574fcc 304 SUPERFAMILY SSF53474 64 304 7.9E-28 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS06345 4acab3a0ab4d356f57d598fc81574fcc 304 Pfam PF01738 Dienelactone hydrolase family 120 284 6.2E-8 T 11-11-2016 IPR002925 Dienelactone hydrolase GO:0016787 AUP74_RS01845 8db5e8e18cfbfeed68433a821dccd297 749 SUPERFAMILY SSF56719 33 485 3.92E-157 T 11-11-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AUP74_RS01845 8db5e8e18cfbfeed68433a821dccd297 749 Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. 6 745 33.788 T 11-11-2016 IPR005742 DNA topoisomerase IV, subunit A, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AUP74_RS01845 8db5e8e18cfbfeed68433a821dccd297 749 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 598 635 0.011 T 11-11-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AUP74_RS01845 8db5e8e18cfbfeed68433a821dccd297 749 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 650 697 2.2E-6 T 11-11-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AUP74_RS01845 8db5e8e18cfbfeed68433a821dccd297 749 SUPERFAMILY SSF101904 500 743 8.11E-50 T 11-11-2016 AUP74_RS01845 8db5e8e18cfbfeed68433a821dccd297 749 Gene3D G3DSA:3.30.1360.40 240 333 5.2E-26 T 11-11-2016 IPR024946 Arginine repressor C-terminal-like domain AUP74_RS01845 8db5e8e18cfbfeed68433a821dccd297 749 SMART SM00434 13 463 1.9E-231 T 11-11-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS01845 8db5e8e18cfbfeed68433a821dccd297 749 Gene3D G3DSA:2.120.10.90 498 738 5.3E-24 T 11-11-2016 AUP74_RS01845 8db5e8e18cfbfeed68433a821dccd297 749 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 34 470 2.2E-136 T 11-11-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS01845 8db5e8e18cfbfeed68433a821dccd297 749 TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 11 745 0.0 T 11-11-2016 AUP74_RS01845 8db5e8e18cfbfeed68433a821dccd297 749 Gene3D G3DSA:3.90.199.10 335 399 2.7E-108 T 11-11-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS01845 8db5e8e18cfbfeed68433a821dccd297 749 Gene3D G3DSA:3.90.199.10 33 239 2.7E-108 T 11-11-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS00870 2e14082f002296c9b9c97ef0084a6244 502 SUPERFAMILY SSF48452 328 481 1.42E-15 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS00870 2e14082f002296c9b9c97ef0084a6244 502 SUPERFAMILY SSF48452 176 391 3.04E-7 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS00870 2e14082f002296c9b9c97ef0084a6244 502 Pfam PF14559 Tetratricopeptide repeat 371 435 1.1E-10 T 11-11-2016 AUP74_RS00870 2e14082f002296c9b9c97ef0084a6244 502 Pfam PF01435 Peptidase family M48 89 275 1.7E-33 T 11-11-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 AUP74_RS00870 2e14082f002296c9b9c97ef0084a6244 502 Gene3D G3DSA:1.25.40.10 284 489 2.6E-18 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS00870 2e14082f002296c9b9c97ef0084a6244 502 Gene3D G3DSA:3.30.2010.10 86 168 5.9E-18 T 11-11-2016 AUP74_RS00870 2e14082f002296c9b9c97ef0084a6244 502 Hamap MF_00997 Beta-barrel assembly-enhancing protease [bepA]. 36 502 35.811 T 11-11-2016 IPR030873 Beta-barrel assembly-enhancing protease GO:0006508|GO:0008237|GO:0016020|GO:0061077 AUP74_RS04455 64827bec592bec5fa34579b64bcd53b7 552 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 4 547 23.676 T 11-11-2016 IPR019998 Membrane insertase YidC GO:0016021|GO:0051205 AUP74_RS04455 64827bec592bec5fa34579b64bcd53b7 552 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 366 545 1.3E-72 T 11-11-2016 IPR028055 Membrane insertase YidC/Oxa1, C-terminal AUP74_RS04455 64827bec592bec5fa34579b64bcd53b7 552 Pfam PF02096 60Kd inner membrane protein 367 545 5.9E-62 T 11-11-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 AUP74_RS04455 64827bec592bec5fa34579b64bcd53b7 552 Pfam PF14849 YidC periplasmic domain 80 354 9.1E-81 T 11-11-2016 IPR028053 Membrane insertase YidC, N-terminal AUP74_RS04455 64827bec592bec5fa34579b64bcd53b7 552 PRINTS PR01900 YidC translocation/secretion protein signature 481 496 3.3E-18 T 11-11-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 AUP74_RS04455 64827bec592bec5fa34579b64bcd53b7 552 PRINTS PR01900 YidC translocation/secretion protein signature 500 524 3.3E-18 T 11-11-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 AUP74_RS04455 64827bec592bec5fa34579b64bcd53b7 552 PRINTS PR01900 YidC translocation/secretion protein signature 352 368 3.3E-18 T 11-11-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 AUP74_RS04455 64827bec592bec5fa34579b64bcd53b7 552 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 3 361 1.9E-100 T 11-11-2016 IPR028053 Membrane insertase YidC, N-terminal AUP74_RS04455 64827bec592bec5fa34579b64bcd53b7 552 PRINTS PR00701 60kDa inner membrane protein signature 2 23 4.1E-81 T 11-11-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 AUP74_RS04455 64827bec592bec5fa34579b64bcd53b7 552 PRINTS PR00701 60kDa inner membrane protein signature 336 356 4.1E-81 T 11-11-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 AUP74_RS04455 64827bec592bec5fa34579b64bcd53b7 552 PRINTS PR00701 60kDa inner membrane protein signature 263 278 4.1E-81 T 11-11-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 AUP74_RS04455 64827bec592bec5fa34579b64bcd53b7 552 PRINTS PR00701 60kDa inner membrane protein signature 85 106 4.1E-81 T 11-11-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 AUP74_RS04455 64827bec592bec5fa34579b64bcd53b7 552 PRINTS PR00701 60kDa inner membrane protein signature 428 451 4.1E-81 T 11-11-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 AUP74_RS04455 64827bec592bec5fa34579b64bcd53b7 552 PRINTS PR00701 60kDa inner membrane protein signature 475 497 4.1E-81 T 11-11-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 AUP74_RS04455 64827bec592bec5fa34579b64bcd53b7 552 PRINTS PR00701 60kDa inner membrane protein signature 175 195 4.1E-81 T 11-11-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 AUP74_RS04455 64827bec592bec5fa34579b64bcd53b7 552 PRINTS PR00701 60kDa inner membrane protein signature 511 534 4.1E-81 T 11-11-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 AUP74_RS04455 64827bec592bec5fa34579b64bcd53b7 552 PRINTS PR00701 60kDa inner membrane protein signature 230 248 4.1E-81 T 11-11-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 AUP74_RS11395 94a0798f0009ef7149d066740934b78d 1052 SUPERFAMILY SSF82693 269 325 8.37E-14 T 11-11-2016 AUP74_RS11395 94a0798f0009ef7149d066740934b78d 1052 SUPERFAMILY SSF82693 148 183 8.37E-14 T 11-11-2016 AUP74_RS11395 94a0798f0009ef7149d066740934b78d 1052 SUPERFAMILY SSF82693 39 130 5.75E-14 T 11-11-2016 AUP74_RS11395 94a0798f0009ef7149d066740934b78d 1052 Gene3D G3DSA:3.30.2090.10 708 791 1.0E-6 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS11395 94a0798f0009ef7149d066740934b78d 1052 SUPERFAMILY SSF82866 301 492 6.67E-38 T 11-11-2016 AUP74_RS11395 94a0798f0009ef7149d066740934b78d 1052 Gene3D G3DSA:1.10.3850.10 277 492 2.0E-47 T 11-11-2016 AUP74_RS11395 94a0798f0009ef7149d066740934b78d 1052 Gene3D G3DSA:1.10.3850.10 801 1036 2.4E-53 T 11-11-2016 AUP74_RS11395 94a0798f0009ef7149d066740934b78d 1052 Gene3D G3DSA:3.30.70.1430 39 137 3.8E-17 T 11-11-2016 AUP74_RS11395 94a0798f0009ef7149d066740934b78d 1052 SUPERFAMILY SSF82866 795 1039 1.44E-41 T 11-11-2016 AUP74_RS11395 94a0798f0009ef7149d066740934b78d 1052 Gene3D G3DSA:3.30.2090.10 184 265 1.7E-14 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS11395 94a0798f0009ef7149d066740934b78d 1052 SUPERFAMILY SSF82714 184 266 1.14E-12 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS11395 94a0798f0009ef7149d066740934b78d 1052 PRINTS PR00702 Acriflavin resistance protein family signature 441 464 5.7E-39 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS11395 94a0798f0009ef7149d066740934b78d 1052 PRINTS PR00702 Acriflavin resistance protein family signature 539 556 5.7E-39 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS11395 94a0798f0009ef7149d066740934b78d 1052 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 5.7E-39 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS11395 94a0798f0009ef7149d066740934b78d 1052 PRINTS PR00702 Acriflavin resistance protein family signature 466 489 5.7E-39 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS11395 94a0798f0009ef7149d066740934b78d 1052 PRINTS PR00702 Acriflavin resistance protein family signature 360 381 5.7E-39 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS11395 94a0798f0009ef7149d066740934b78d 1052 PRINTS PR00702 Acriflavin resistance protein family signature 388 412 5.7E-39 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS11395 94a0798f0009ef7149d066740934b78d 1052 PRINTS PR00702 Acriflavin resistance protein family signature 333 356 5.7E-39 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS11395 94a0798f0009ef7149d066740934b78d 1052 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 5.7E-39 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS11395 94a0798f0009ef7149d066740934b78d 1052 SUPERFAMILY SSF82714 709 793 1.31E-9 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS11395 94a0798f0009ef7149d066740934b78d 1052 Pfam PF00873 AcrB/AcrD/AcrF family 1 1033 2.1E-177 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS16840 be83378b4f43f9a2aa8b6167de9f22a6 397 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 223 328 7.2E-24 T 11-11-2016 IPR000160 GGDEF domain AUP74_RS16840 be83378b4f43f9a2aa8b6167de9f22a6 397 Gene3D G3DSA:3.30.70.270 226 394 3.3E-43 T 11-11-2016 AUP74_RS16840 be83378b4f43f9a2aa8b6167de9f22a6 397 Pfam PF00990 Diguanylate cyclase, GGDEF domain 224 332 1.5E-21 T 11-11-2016 IPR000160 GGDEF domain AUP74_RS16840 be83378b4f43f9a2aa8b6167de9f22a6 397 Pfam PF00990 Diguanylate cyclase, GGDEF domain 347 392 5.3E-6 T 11-11-2016 IPR000160 GGDEF domain AUP74_RS16840 be83378b4f43f9a2aa8b6167de9f22a6 397 SUPERFAMILY SSF55073 229 394 2.28E-35 T 11-11-2016 IPR029787 Nucleotide cyclase AUP74_RS16840 be83378b4f43f9a2aa8b6167de9f22a6 397 SMART SM00267 212 396 3.2E-35 T 11-11-2016 IPR000160 GGDEF domain AUP74_RS09470 c17df24b649955afb1ed70b261cf1a1d 293 Gene3D G3DSA:1.10.760.10 206 289 1.1E-27 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS09470 c17df24b649955afb1ed70b261cf1a1d 293 PRINTS PR00605 Class IC cytochrome C signature 130 141 1.3E-5 T 11-11-2016 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 AUP74_RS09470 c17df24b649955afb1ed70b261cf1a1d 293 PRINTS PR00605 Class IC cytochrome C signature 260 282 1.3E-5 T 11-11-2016 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 AUP74_RS09470 c17df24b649955afb1ed70b261cf1a1d 293 Pfam PF14715 N-terminal domain of cytochrome oxidase-cbb3, FixP 31 77 6.8E-23 T 11-11-2016 IPR032858 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal AUP74_RS09470 c17df24b649955afb1ed70b261cf1a1d 293 PIRSF PIRSF000006 1 289 1.1E-97 T 11-11-2016 IPR004678 Cytochrome c oxidase cbb3-type, subunit III AUP74_RS09470 c17df24b649955afb1ed70b261cf1a1d 293 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 207 282 1.9E-12 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS09470 c17df24b649955afb1ed70b261cf1a1d 293 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 120 194 9.0E-12 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS09470 c17df24b649955afb1ed70b261cf1a1d 293 Gene3D G3DSA:1.10.760.10 55 76 5.6E-27 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS09470 c17df24b649955afb1ed70b261cf1a1d 293 Gene3D G3DSA:1.10.760.10 115 204 5.6E-27 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS09470 c17df24b649955afb1ed70b261cf1a1d 293 TIGRFAM TIGR00782 ccoP: cytochrome c oxidase, cbb3-type, subunit III 27 288 4.9E-85 T 11-11-2016 IPR004678 Cytochrome c oxidase cbb3-type, subunit III AUP74_RS09470 c17df24b649955afb1ed70b261cf1a1d 293 SUPERFAMILY SSF46626 49 72 1.17E-30 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS09470 c17df24b649955afb1ed70b261cf1a1d 293 SUPERFAMILY SSF46626 100 203 1.17E-30 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS09470 c17df24b649955afb1ed70b261cf1a1d 293 SUPERFAMILY SSF46626 203 288 1.41E-25 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS06560 b1a96b6f6103540d242e91e8e6cb9a52 877 Gene3D G3DSA:1.10.3810.10 164 334 5.8E-60 T 11-11-2016 AUP74_RS06560 b1a96b6f6103540d242e91e8e6cb9a52 877 Gene3D G3DSA:3.30.2060.10 68 152 1.1E-13 T 11-11-2016 AUP74_RS06560 b1a96b6f6103540d242e91e8e6cb9a52 877 Pfam PF14814 Bifunctional transglycosylase second domain 68 151 7.0E-16 T 11-11-2016 IPR028166 Bifunctional transglycosylase second domain KEGG: 00500+2.4.1.12|KEGG: 00550+2.4.1.129|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AUP74_RS06560 b1a96b6f6103540d242e91e8e6cb9a52 877 Pfam PF00905 Penicillin binding protein transpeptidase domain 429 671 2.7E-24 T 11-11-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 AUP74_RS06560 b1a96b6f6103540d242e91e8e6cb9a52 877 Gene3D G3DSA:1.20.5.100 14 51 4.9E-6 T 11-11-2016 AUP74_RS06560 b1a96b6f6103540d242e91e8e6cb9a52 877 Gene3D G3DSA:3.40.710.10 335 740 1.1E-106 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS06560 b1a96b6f6103540d242e91e8e6cb9a52 877 Pfam PF00912 Transglycosylase 163 333 1.1E-53 T 11-11-2016 IPR001264 Glycosyl transferase, family 51 AUP74_RS06560 b1a96b6f6103540d242e91e8e6cb9a52 877 PIRSF PIRSF002799 1 778 4.7E-266 T 11-11-2016 IPR011813 Penicillin-binding protein 1B GO:0008233|GO:0008955|GO:0009252|GO:0009274|GO:0046677 KEGG: 00500+2.4.1.12|KEGG: 00550+2.4.1.129|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AUP74_RS06560 b1a96b6f6103540d242e91e8e6cb9a52 877 SUPERFAMILY SSF53955 151 355 6.75E-63 T 11-11-2016 IPR023346 Lysozyme-like domain AUP74_RS06560 b1a96b6f6103540d242e91e8e6cb9a52 877 TIGRFAM TIGR02071 PBP_1b: penicillin-binding protein 1B 27 743 1.9E-242 T 11-11-2016 IPR011813 Penicillin-binding protein 1B GO:0008233|GO:0008955|GO:0009252|GO:0009274|GO:0046677 KEGG: 00500+2.4.1.12|KEGG: 00550+2.4.1.129|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AUP74_RS06560 b1a96b6f6103540d242e91e8e6cb9a52 877 SUPERFAMILY SSF56601 315 337 2.82E-110 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS06560 b1a96b6f6103540d242e91e8e6cb9a52 877 SUPERFAMILY SSF56601 366 750 2.82E-110 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS10475 1114ecb832123c6d9dc780f053cf2b40 210 Pfam PF04367 Protein of unknown function (DUF502) 65 163 2.1E-6 T 11-11-2016 IPR007462 Protein of unknown function DUF502 AUP74_RS09385 9a35c6a715ed7bd0c8b0ec1fad5b71bd 343 Pfam PF00107 Zinc-binding dehydrogenase 156 250 1.5E-13 T 11-11-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AUP74_RS09385 9a35c6a715ed7bd0c8b0ec1fad5b71bd 343 SUPERFAMILY SSF51735 116 252 1.71E-34 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS09385 9a35c6a715ed7bd0c8b0ec1fad5b71bd 343 Gene3D G3DSA:3.40.50.720 151 245 1.7E-19 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS09385 9a35c6a715ed7bd0c8b0ec1fad5b71bd 343 SMART SM00829 14 338 5.0E-61 T 11-11-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AUP74_RS09385 9a35c6a715ed7bd0c8b0ec1fad5b71bd 343 SUPERFAMILY SSF50129 4 150 8.67E-33 T 11-11-2016 IPR011032 GroES-like AUP74_RS09385 9a35c6a715ed7bd0c8b0ec1fad5b71bd 343 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 93 1.3E-6 T 11-11-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AUP74_RS09385 9a35c6a715ed7bd0c8b0ec1fad5b71bd 343 Gene3D G3DSA:3.90.180.10 6 150 3.5E-41 T 11-11-2016 IPR011032 GroES-like AUP74_RS07755 1e3a4500e04290cde426b12933cc0238 406 Pfam PF13480 Acetyltransferase (GNAT) domain 199 343 1.8E-20 T 11-11-2016 AUP74_RS07755 1e3a4500e04290cde426b12933cc0238 406 SUPERFAMILY SSF55729 198 357 2.73E-17 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 SUPERFAMILY SSF56719 395 561 4.97E-88 T 11-11-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 SUPERFAMILY SSF56719 732 796 4.97E-88 T 11-11-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 Pfam PF01751 Toprim domain 420 532 5.7E-18 T 11-11-2016 IPR006171 Toprim domain AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 4 806 104.387 T 11-11-2016 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 34 176 1.9E-24 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 Gene3D G3DSA:3.30.230.10 221 393 9.1E-74 T 11-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 734 795 6.4E-32 T 11-11-2016 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 Gene3D G3DSA:3.30.565.10 17 219 1.5E-92 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 7 806 1.3E-304 T 11-11-2016 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 Gene3D G3DSA:3.40.50.670 405 551 4.0E-102 T 11-11-2016 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 Gene3D G3DSA:3.40.50.670 720 788 4.0E-102 T 11-11-2016 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 PRINTS PR01159 DNA gyrase subunit B signature 361 375 8.2E-76 T 11-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 PRINTS PR01159 DNA gyrase subunit B signature 471 480 8.2E-76 T 11-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 PRINTS PR01159 DNA gyrase subunit B signature 182 197 8.2E-76 T 11-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 PRINTS PR01159 DNA gyrase subunit B signature 313 329 8.2E-76 T 11-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 PRINTS PR01159 DNA gyrase subunit B signature 197 210 8.2E-76 T 11-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 PRINTS PR01159 DNA gyrase subunit B signature 221 243 8.2E-76 T 11-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 PRINTS PR01159 DNA gyrase subunit B signature 775 791 8.2E-76 T 11-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 PRINTS PR01159 DNA gyrase subunit B signature 375 395 8.2E-76 T 11-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 PRINTS PR01159 DNA gyrase subunit B signature 7 17 8.2E-76 T 11-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 PRINTS PR01159 DNA gyrase subunit B signature 759 771 8.2E-76 T 11-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 SUPERFAMILY SSF54211 222 393 2.09E-58 T 11-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 Pfam PF00204 DNA gyrase B 222 391 1.5E-57 T 11-11-2016 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 SMART SM00433 37 799 3.8E-280 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 SMART SM00387 33 177 4.0E-30 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 ProSitePatterns PS00177 DNA topoisomerase II signature. 423 431 - T 11-11-2016 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 SUPERFAMILY SSF55874 7 219 1.44E-74 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 PRINTS PR00418 DNA topoisomerase II family signature 738 754 5.0E-70 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 PRINTS PR00418 DNA topoisomerase II family signature 115 129 5.0E-70 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 PRINTS PR00418 DNA topoisomerase II family signature 269 282 5.0E-70 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 PRINTS PR00418 DNA topoisomerase II family signature 526 538 5.0E-70 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 PRINTS PR00418 DNA topoisomerase II family signature 506 523 5.0E-70 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 PRINTS PR00418 DNA topoisomerase II family signature 72 85 5.0E-70 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 PRINTS PR00418 DNA topoisomerase II family signature 421 435 5.0E-70 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 PRINTS PR00418 DNA topoisomerase II family signature 37 52 5.0E-70 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS04485 e8074c03c637990127a7272f5217c687 806 PRINTS PR00418 DNA topoisomerase II family signature 488 504 5.0E-70 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS14820 283a8213052d69bb1e8886051915e754 854 SUPERFAMILY SSF101904 534 850 6.8E-106 T 11-11-2016 AUP74_RS14820 283a8213052d69bb1e8886051915e754 854 Gene3D G3DSA:1.10.268.10 363 497 1.7E-45 T 11-11-2016 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS14820 283a8213052d69bb1e8886051915e754 854 Gene3D G3DSA:3.30.1360.40 236 333 1.1E-34 T 11-11-2016 IPR024946 Arginine repressor C-terminal-like domain AUP74_RS14820 283a8213052d69bb1e8886051915e754 854 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 539 586 3.0E-9 T 11-11-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AUP74_RS14820 283a8213052d69bb1e8886051915e754 854 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 744 787 1.4E-11 T 11-11-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AUP74_RS14820 283a8213052d69bb1e8886051915e754 854 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 589 639 1.4E-11 T 11-11-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AUP74_RS14820 283a8213052d69bb1e8886051915e754 854 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 647 689 7.5E-8 T 11-11-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AUP74_RS14820 283a8213052d69bb1e8886051915e754 854 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 794 840 6.4E-14 T 11-11-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AUP74_RS14820 283a8213052d69bb1e8886051915e754 854 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 694 738 5.9E-10 T 11-11-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AUP74_RS14820 283a8213052d69bb1e8886051915e754 854 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 32 507 6.1E-153 T 11-11-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS14820 283a8213052d69bb1e8886051915e754 854 Gene3D G3DSA:3.90.199.10 34 216 3.3E-86 T 11-11-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS14820 283a8213052d69bb1e8886051915e754 854 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 8 841 0.0 T 11-11-2016 AUP74_RS14820 283a8213052d69bb1e8886051915e754 854 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 5 842 24.054 T 11-11-2016 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AUP74_RS14820 283a8213052d69bb1e8886051915e754 854 SMART SM00434 11 500 5.2E-292 T 11-11-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS14820 283a8213052d69bb1e8886051915e754 854 Gene3D G3DSA:2.120.10.90 532 840 3.6E-130 T 11-11-2016 AUP74_RS14820 283a8213052d69bb1e8886051915e754 854 SUPERFAMILY SSF56719 30 523 1.19E-181 T 11-11-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AUP74_RS15540 5d9cf95dca8f63466f46923bdc98fbeb 248 SUPERFAMILY SSF52833 105 246 4.37E-28 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS15540 5d9cf95dca8f63466f46923bdc98fbeb 248 Gene3D G3DSA:3.40.30.10 120 246 1.4E-35 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS15540 5d9cf95dca8f63466f46923bdc98fbeb 248 Pfam PF13098 Thioredoxin-like domain 121 246 3.1E-24 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS15540 5d9cf95dca8f63466f46923bdc98fbeb 248 Pfam PF10411 Disulfide bond isomerase protein N-terminus 35 88 1.0E-14 T 11-11-2016 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal AUP74_RS15540 5d9cf95dca8f63466f46923bdc98fbeb 248 Gene3D G3DSA:3.10.450.70 32 93 3.5E-16 T 11-11-2016 IPR009094 Disulphide bond isomerase, DsbC, N-terminal AUP74_RS15540 5d9cf95dca8f63466f46923bdc98fbeb 248 SUPERFAMILY SSF54423 34 90 1.31E-10 T 11-11-2016 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal AUP74_RS01825 c95095c6b84b2e06bb0b1824f44a2ec1 157 Pfam PF01047 MarR family 49 106 1.6E-15 T 11-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AUP74_RS01825 c95095c6b84b2e06bb0b1824f44a2ec1 157 SMART SM00347 42 142 7.1E-23 T 11-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AUP74_RS01825 c95095c6b84b2e06bb0b1824f44a2ec1 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 98 2.9E-13 T 11-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AUP74_RS01825 c95095c6b84b2e06bb0b1824f44a2ec1 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 102 118 2.9E-13 T 11-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AUP74_RS01825 c95095c6b84b2e06bb0b1824f44a2ec1 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 132 152 2.9E-13 T 11-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AUP74_RS01825 c95095c6b84b2e06bb0b1824f44a2ec1 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 82 2.9E-13 T 11-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AUP74_RS01825 c95095c6b84b2e06bb0b1824f44a2ec1 157 SUPERFAMILY SSF46785 22 156 6.51E-34 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS01825 c95095c6b84b2e06bb0b1824f44a2ec1 157 Gene3D G3DSA:1.10.10.10 20 156 3.1E-35 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS06495 0bb064dc64b7b6490a0684847484d564 102 Pfam PF02954 Bacterial regulatory protein, Fis family 59 99 6.5E-15 T 11-11-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AUP74_RS06495 0bb064dc64b7b6490a0684847484d564 102 Gene3D G3DSA:1.10.10.60 31 101 8.9E-26 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS06495 0bb064dc64b7b6490a0684847484d564 102 SUPERFAMILY SSF46689 24 101 1.88E-23 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS06495 0bb064dc64b7b6490a0684847484d564 102 PIRSF PIRSF002097 6 102 9.1E-39 T 11-11-2016 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 AUP74_RS06495 0bb064dc64b7b6490a0684847484d564 102 PRINTS PR01591 DNA-binding protein FIS signature 30 46 1.3E-12 T 11-11-2016 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 AUP74_RS06495 0bb064dc64b7b6490a0684847484d564 102 PRINTS PR01591 DNA-binding protein FIS signature 61 73 1.3E-12 T 11-11-2016 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 AUP74_RS06495 0bb064dc64b7b6490a0684847484d564 102 PRINTS PR01591 DNA-binding protein FIS signature 46 61 1.3E-12 T 11-11-2016 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 AUP74_RS06495 0bb064dc64b7b6490a0684847484d564 102 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 65 82 4.8E-12 T 11-11-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AUP74_RS06495 0bb064dc64b7b6490a0684847484d564 102 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 82 102 4.8E-12 T 11-11-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AUP74_RS07515 7815a53aa943cb7a67e1ab90d0d7d527 307 SUPERFAMILY SSF52540 59 303 2.3E-23 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS07515 7815a53aa943cb7a67e1ab90d0d7d527 307 Gene3D G3DSA:3.40.50.300 41 302 8.2E-73 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS00905 b53396c7317abb8ab214dc70c6bfaf0f 159 PRINTS PR01021 OMPA domain signature 104 120 2.5E-17 T 11-11-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AUP74_RS00905 b53396c7317abb8ab214dc70c6bfaf0f 159 PRINTS PR01021 OMPA domain signature 60 82 2.5E-17 T 11-11-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AUP74_RS00905 b53396c7317abb8ab214dc70c6bfaf0f 159 PRINTS PR01021 OMPA domain signature 89 104 2.5E-17 T 11-11-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AUP74_RS00905 b53396c7317abb8ab214dc70c6bfaf0f 159 ProSitePatterns PS01068 OmpA-like domain. 91 135 - T 11-11-2016 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 AUP74_RS00905 b53396c7317abb8ab214dc70c6bfaf0f 159 Pfam PF00691 OmpA family 59 153 3.2E-19 T 11-11-2016 IPR006665 OmpA-like domain AUP74_RS00905 b53396c7317abb8ab214dc70c6bfaf0f 159 Gene3D G3DSA:3.30.1330.60 37 158 4.5E-32 T 11-11-2016 IPR006665 OmpA-like domain AUP74_RS00905 b53396c7317abb8ab214dc70c6bfaf0f 159 SUPERFAMILY SSF103088 35 158 2.75E-33 T 11-11-2016 IPR006665 OmpA-like domain AUP74_RS04025 36257c86d5c3d66d2ba61354376ab73d 218 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 11 188 1.1E-60 T 11-11-2016 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 AUP74_RS04025 36257c86d5c3d66d2ba61354376ab73d 218 Gene3D G3DSA:3.40.50.2020 7 213 1.6E-78 T 11-11-2016 IPR029057 Phosphoribosyltransferase-like AUP74_RS04025 36257c86d5c3d66d2ba61354376ab73d 218 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 218 33.427 T 11-11-2016 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 AUP74_RS04025 36257c86d5c3d66d2ba61354376ab73d 218 SUPERFAMILY SSF53271 1 212 1.52E-45 T 11-11-2016 IPR029057 Phosphoribosyltransferase-like AUP74_RS04025 36257c86d5c3d66d2ba61354376ab73d 218 Pfam PF00156 Phosphoribosyl transferase domain 41 160 5.6E-13 T 11-11-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 AUP74_RS11775 dbd73d852c3353a9fd26b9c12f095fd2 323 PIRSF PIRSF002849 1 323 1.2E-128 T 11-11-2016 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted AUP74_RS11775 dbd73d852c3353a9fd26b9c12f095fd2 323 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 41 171 7.9E-64 T 11-11-2016 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 AUP74_RS11775 dbd73d852c3353a9fd26b9c12f095fd2 323 Gene3D G3DSA:3.40.50.300 22 187 2.4E-42 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11775 dbd73d852c3353a9fd26b9c12f095fd2 323 Gene3D G3DSA:1.10.8.300 205 320 2.4E-42 T 11-11-2016 AUP74_RS11775 dbd73d852c3353a9fd26b9c12f095fd2 323 SUPERFAMILY SSF52540 9 296 4.76E-40 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04770 341dc570baecce1da84e84411cbaf730 259 Pfam PF00005 ABC transporter 23 153 3.5E-27 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AUP74_RS04770 341dc570baecce1da84e84411cbaf730 259 SUPERFAMILY SSF52540 4 218 4.44E-52 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04770 341dc570baecce1da84e84411cbaf730 259 SMART SM00382 32 201 2.7E-11 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS04770 341dc570baecce1da84e84411cbaf730 259 Gene3D G3DSA:3.40.50.300 5 218 2.1E-53 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04770 341dc570baecce1da84e84411cbaf730 259 ProSitePatterns PS00211 ABC transporters family signature. 125 139 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AUP74_RS13680 c743b97d3294ae1bb0ddee7faff7f226 431 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 21 417 2.1E-46 T 11-11-2016 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) AUP74_RS13680 c743b97d3294ae1bb0ddee7faff7f226 431 SUPERFAMILY SSF56935 31 429 1.21E-55 T 11-11-2016 AUP74_RS13680 c743b97d3294ae1bb0ddee7faff7f226 431 Gene3D G3DSA:2.40.160.60 34 428 3.3E-73 T 11-11-2016 AUP74_RS10090 dd40a6c9f990dbf3984713c2efa102d6 163 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 2 154 1.1E-68 T 11-11-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 AUP74_RS10090 dd40a6c9f990dbf3984713c2efa102d6 163 Gene3D G3DSA:3.30.1330.50 1 155 4.8E-71 T 11-11-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 AUP74_RS10090 dd40a6c9f990dbf3984713c2efa102d6 163 Pfam PF02542 YgbB family 1 154 3.2E-66 T 11-11-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 AUP74_RS10090 dd40a6c9f990dbf3984713c2efa102d6 163 SUPERFAMILY SSF69765 1 155 6.28E-66 T 11-11-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 AUP74_RS10090 dd40a6c9f990dbf3984713c2efa102d6 163 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 1 156 35.611 T 11-11-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 AUP74_RS10090 dd40a6c9f990dbf3984713c2efa102d6 163 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 35 50 - T 11-11-2016 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 AUP74_RS05670 fdc405ba41ce2278b0c6c45243cc241c 140 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 7 135 6.7E-40 T 11-11-2016 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 AUP74_RS05670 fdc405ba41ce2278b0c6c45243cc241c 140 Gene3D G3DSA:3.30.420.140 5 138 2.8E-42 T 11-11-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 AUP74_RS05670 fdc405ba41ce2278b0c6c45243cc241c 140 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 4 139 22.996 T 11-11-2016 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 AUP74_RS05670 fdc405ba41ce2278b0c6c45243cc241c 140 SUPERFAMILY SSF53098 5 136 2.58E-39 T 11-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 AUP74_RS05670 fdc405ba41ce2278b0c6c45243cc241c 140 Pfam PF03652 Holliday junction resolvase 5 136 8.2E-39 T 11-11-2016 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 AUP74_RS05670 fdc405ba41ce2278b0c6c45243cc241c 140 SMART SM00732 4 104 5.6E-30 T 11-11-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 AUP74_RS12795 8dd8f11dbbcbdf54adf36f9e5d75b94b 203 Hamap MF_00240 Outer-membrane lipoprotein carrier protein [lolA]. 8 202 29.575 T 11-11-2016 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 AUP74_RS12795 8dd8f11dbbcbdf54adf36f9e5d75b94b 203 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 36 192 8.5E-48 T 11-11-2016 IPR004564 Outer membrane lipoprotein carrier protein LolA-like AUP74_RS12795 8dd8f11dbbcbdf54adf36f9e5d75b94b 203 SUPERFAMILY SSF89392 22 201 6.28E-48 T 11-11-2016 IPR029046 Lipoprotein localisation LolA/LolB/LppX AUP74_RS12795 8dd8f11dbbcbdf54adf36f9e5d75b94b 203 TIGRFAM TIGR00547 lolA: outer membrane lipoprotein carrier protein LolA 2 199 1.1E-29 T 11-11-2016 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 AUP74_RS12795 8dd8f11dbbcbdf54adf36f9e5d75b94b 203 Gene3D G3DSA:2.50.20.10 23 201 2.0E-55 T 11-11-2016 AUP74_RS02640 29751c1f382faa5f1c81fa7d666385c1 446 Gene3D G3DSA:3.90.1150.10 345 441 3.0E-35 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS02640 29751c1f382faa5f1c81fa7d666385c1 446 Gene3D G3DSA:3.90.1150.10 8 65 3.0E-35 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS02640 29751c1f382faa5f1c81fa7d666385c1 446 Pfam PF00202 Aminotransferase class-III 27 439 4.6E-109 T 11-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AUP74_RS02640 29751c1f382faa5f1c81fa7d666385c1 446 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 251 288 - T 11-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AUP74_RS02640 29751c1f382faa5f1c81fa7d666385c1 446 Gene3D G3DSA:3.40.640.10 67 343 2.7E-80 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AUP74_RS02640 29751c1f382faa5f1c81fa7d666385c1 446 SUPERFAMILY SSF53383 24 440 3.06E-113 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase AUP74_RS11845 a2dfcaa3d986521a47ceb29128aea3db 905 Pfam PF01751 Toprim domain 5 154 1.4E-32 T 11-11-2016 IPR006171 Toprim domain AUP74_RS11845 a2dfcaa3d986521a47ceb29128aea3db 905 Gene3D G3DSA:2.20.25.10 818 873 2.1E-28 T 11-11-2016 AUP74_RS11845 a2dfcaa3d986521a47ceb29128aea3db 905 Pfam PF01131 DNA topoisomerase 169 576 8.9E-128 T 11-11-2016 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AUP74_RS11845 a2dfcaa3d986521a47ceb29128aea3db 905 Gene3D G3DSA:3.30.65.10 717 754 2.5E-10 T 11-11-2016 AUP74_RS11845 a2dfcaa3d986521a47ceb29128aea3db 905 Gene3D G3DSA:3.30.65.10 755 815 3.9E-23 T 11-11-2016 AUP74_RS11845 a2dfcaa3d986521a47ceb29128aea3db 905 Gene3D G3DSA:3.30.65.10 597 645 1.4E-13 T 11-11-2016 AUP74_RS11845 a2dfcaa3d986521a47ceb29128aea3db 905 SMART SM00437 284 539 6.3E-115 T 11-11-2016 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 AUP74_RS11845 a2dfcaa3d986521a47ceb29128aea3db 905 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 733 55.958 T 11-11-2016 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 AUP74_RS11845 a2dfcaa3d986521a47ceb29128aea3db 905 SUPERFAMILY SSF56712 3 619 3.4E-199 T 11-11-2016 IPR023405 DNA topoisomerase, type IA, core domain AUP74_RS11845 a2dfcaa3d986521a47ceb29128aea3db 905 SMART SM00493 3 144 1.2E-31 T 11-11-2016 IPR006171 Toprim domain AUP74_RS11845 a2dfcaa3d986521a47ceb29128aea3db 905 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 321 335 - T 11-11-2016 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 AUP74_RS11845 a2dfcaa3d986521a47ceb29128aea3db 905 SUPERFAMILY SSF57783 710 753 4.76E-7 T 11-11-2016 AUP74_RS11845 a2dfcaa3d986521a47ceb29128aea3db 905 Gene3D G3DSA:2.70.20.10 225 347 1.4E-34 T 11-11-2016 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 AUP74_RS11845 a2dfcaa3d986521a47ceb29128aea3db 905 Gene3D G3DSA:2.70.20.10 350 485 1.2E-35 T 11-11-2016 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 AUP74_RS11845 a2dfcaa3d986521a47ceb29128aea3db 905 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 326 335 1.8E-36 T 11-11-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 AUP74_RS11845 a2dfcaa3d986521a47ceb29128aea3db 905 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 203 221 1.8E-36 T 11-11-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 AUP74_RS11845 a2dfcaa3d986521a47ceb29128aea3db 905 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 402 418 1.8E-36 T 11-11-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 AUP74_RS11845 a2dfcaa3d986521a47ceb29128aea3db 905 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 502 516 1.8E-36 T 11-11-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 AUP74_RS11845 a2dfcaa3d986521a47ceb29128aea3db 905 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 118 131 1.8E-36 T 11-11-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 AUP74_RS11845 a2dfcaa3d986521a47ceb29128aea3db 905 SUPERFAMILY SSF57783 819 873 8.5E-22 T 11-11-2016 AUP74_RS11845 a2dfcaa3d986521a47ceb29128aea3db 905 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 719 755 4.6E-11 T 11-11-2016 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 AUP74_RS11845 a2dfcaa3d986521a47ceb29128aea3db 905 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 607 632 1.1E-6 T 11-11-2016 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 AUP74_RS11845 a2dfcaa3d986521a47ceb29128aea3db 905 SUPERFAMILY SSF57783 754 814 3.06E-17 T 11-11-2016 AUP74_RS11845 a2dfcaa3d986521a47ceb29128aea3db 905 Gene3D G3DSA:3.40.50.140 1 175 1.5E-56 T 11-11-2016 IPR006171 Toprim domain AUP74_RS11845 a2dfcaa3d986521a47ceb29128aea3db 905 SMART SM00436 145 233 3.8E-49 T 11-11-2016 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 AUP74_RS11845 a2dfcaa3d986521a47ceb29128aea3db 905 Gene3D G3DSA:1.10.460.10 176 223 1.5E-56 T 11-11-2016 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 AUP74_RS11845 a2dfcaa3d986521a47ceb29128aea3db 905 Gene3D G3DSA:1.10.460.10 486 590 1.5E-56 T 11-11-2016 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 AUP74_RS11845 a2dfcaa3d986521a47ceb29128aea3db 905 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 644 3.2E-249 T 11-11-2016 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 AUP74_RS11845 a2dfcaa3d986521a47ceb29128aea3db 905 Pfam PF08272 Topoisomerase I zinc-ribbon-like 768 803 1.2E-12 T 11-11-2016 IPR013263 DNA topoisomerase I, zinc ribbon-like, bacterial-type GO:0003677|GO:0003917|GO:0006265 AUP74_RS11845 a2dfcaa3d986521a47ceb29128aea3db 905 Pfam PF08272 Topoisomerase I zinc-ribbon-like 834 873 2.1E-20 T 11-11-2016 IPR013263 DNA topoisomerase I, zinc ribbon-like, bacterial-type GO:0003677|GO:0003917|GO:0006265 AUP74_RS16575 c62c771d069e14be637a15e48c5be808 122 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 10 108 1.3E-8 T 11-11-2016 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AUP74_RS16575 c62c771d069e14be637a15e48c5be808 122 SUPERFAMILY SSF81343 5 122 4.58E-27 T 11-11-2016 AUP74_RS16575 c62c771d069e14be637a15e48c5be808 122 PIRSF PIRSF000169 1 122 2.4E-39 T 11-11-2016 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 AUP74_RS16575 c62c771d069e14be637a15e48c5be808 122 Gene3D G3DSA:1.20.1300.10 1 122 3.6E-35 T 11-11-2016 AUP74_RS16575 c62c771d069e14be637a15e48c5be808 122 TIGRFAM TIGR02968 succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein 10 120 1.6E-32 T 11-11-2016 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 AUP74_RS04890 249e896ef06bcac09460cab2dfdc4f3f 175 SUPERFAMILY SSF50814 5 172 8.73E-54 T 11-11-2016 IPR011038 Calycin-like AUP74_RS04890 249e896ef06bcac09460cab2dfdc4f3f 175 Pfam PF08212 Lipocalin-like domain 29 167 1.7E-45 T 11-11-2016 IPR000566 Lipocalin/cytosolic fatty-acid binding domain AUP74_RS04890 249e896ef06bcac09460cab2dfdc4f3f 175 Gene3D G3DSA:2.40.128.20 10 169 2.6E-54 T 11-11-2016 IPR012674 Calycin AUP74_RS04890 249e896ef06bcac09460cab2dfdc4f3f 175 ProSitePatterns PS00213 Lipocalin signature. 27 40 - T 11-11-2016 IPR022272 Lipocalin family conserved site AUP74_RS04890 249e896ef06bcac09460cab2dfdc4f3f 175 PRINTS PR01171 Bacterial lipocalin signature 28 42 1.4E-36 T 11-11-2016 IPR002446 Lipocalin, bacterial GO:0005215 AUP74_RS04890 249e896ef06bcac09460cab2dfdc4f3f 175 PRINTS PR01171 Bacterial lipocalin signature 98 112 1.4E-36 T 11-11-2016 IPR002446 Lipocalin, bacterial GO:0005215 AUP74_RS04890 249e896ef06bcac09460cab2dfdc4f3f 175 PRINTS PR01171 Bacterial lipocalin signature 157 167 1.4E-36 T 11-11-2016 IPR002446 Lipocalin, bacterial GO:0005215 AUP74_RS04890 249e896ef06bcac09460cab2dfdc4f3f 175 PRINTS PR01171 Bacterial lipocalin signature 64 73 1.4E-36 T 11-11-2016 IPR002446 Lipocalin, bacterial GO:0005215 AUP74_RS04890 249e896ef06bcac09460cab2dfdc4f3f 175 PRINTS PR01171 Bacterial lipocalin signature 115 123 1.4E-36 T 11-11-2016 IPR002446 Lipocalin, bacterial GO:0005215 AUP74_RS04890 249e896ef06bcac09460cab2dfdc4f3f 175 PRINTS PR01171 Bacterial lipocalin signature 130 141 1.4E-36 T 11-11-2016 IPR002446 Lipocalin, bacterial GO:0005215 AUP74_RS04890 249e896ef06bcac09460cab2dfdc4f3f 175 PRINTS PR01171 Bacterial lipocalin signature 45 61 1.4E-36 T 11-11-2016 IPR002446 Lipocalin, bacterial GO:0005215 AUP74_RS04890 249e896ef06bcac09460cab2dfdc4f3f 175 PIRSF PIRSF036893 2 175 8.8E-45 T 11-11-2016 IPR022271 Lipocalin, ApoD type AUP74_RS00655 3db6183cb1fb387069d7dd0be10c658c 872 SUPERFAMILY SSF56935 310 597 2.78E-85 T 11-11-2016 AUP74_RS00655 3db6183cb1fb387069d7dd0be10c658c 872 SUPERFAMILY SSF56935 30 225 2.78E-85 T 11-11-2016 AUP74_RS00655 3db6183cb1fb387069d7dd0be10c658c 872 SUPERFAMILY SSF56935 699 872 2.78E-85 T 11-11-2016 AUP74_RS00655 3db6183cb1fb387069d7dd0be10c658c 872 SUPERFAMILY SSF56935 625 669 2.78E-85 T 11-11-2016 AUP74_RS00655 3db6183cb1fb387069d7dd0be10c658c 872 Gene3D G3DSA:2.40.170.20 292 872 8.9E-71 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS00655 3db6183cb1fb387069d7dd0be10c658c 872 Gene3D G3DSA:2.40.170.20 169 228 8.9E-71 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS00655 3db6183cb1fb387069d7dd0be10c658c 872 Pfam PF07715 TonB-dependent Receptor Plug Domain 53 165 9.0E-20 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS00655 3db6183cb1fb387069d7dd0be10c658c 872 Gene3D G3DSA:2.170.130.10 29 168 2.8E-31 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS00655 3db6183cb1fb387069d7dd0be10c658c 872 Pfam PF00593 TonB dependent receptor 569 870 1.4E-18 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS16890 59eb2feddb5e0ec31d81028c4a7f978d 380 SMART SM00228 279 361 3.7E-11 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS16890 59eb2feddb5e0ec31d81028c4a7f978d 380 Pfam PF13180 PDZ domain 279 369 5.2E-18 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS16890 59eb2feddb5e0ec31d81028c4a7f978d 380 SUPERFAMILY SSF50494 47 276 1.45E-56 T 11-11-2016 IPR009003 Peptidase S1, PA clan AUP74_RS16890 59eb2feddb5e0ec31d81028c4a7f978d 380 Gene3D G3DSA:2.40.10.10 42 163 8.3E-31 T 11-11-2016 AUP74_RS16890 59eb2feddb5e0ec31d81028c4a7f978d 380 Pfam PF13365 Trypsin-like peptidase domain 100 240 6.1E-32 T 11-11-2016 AUP74_RS16890 59eb2feddb5e0ec31d81028c4a7f978d 380 Gene3D G3DSA:2.40.10.10 164 281 6.1E-36 T 11-11-2016 AUP74_RS16890 59eb2feddb5e0ec31d81028c4a7f978d 380 SUPERFAMILY SSF50156 261 369 1.45E-22 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS16890 59eb2feddb5e0ec31d81028c4a7f978d 380 PRINTS PR00834 HtrA/DegQ protease family signature 233 250 3.6E-50 T 11-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AUP74_RS16890 59eb2feddb5e0ec31d81028c4a7f978d 380 PRINTS PR00834 HtrA/DegQ protease family signature 109 121 3.6E-50 T 11-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AUP74_RS16890 59eb2feddb5e0ec31d81028c4a7f978d 380 PRINTS PR00834 HtrA/DegQ protease family signature 170 194 3.6E-50 T 11-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AUP74_RS16890 59eb2feddb5e0ec31d81028c4a7f978d 380 PRINTS PR00834 HtrA/DegQ protease family signature 211 228 3.6E-50 T 11-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AUP74_RS16890 59eb2feddb5e0ec31d81028c4a7f978d 380 PRINTS PR00834 HtrA/DegQ protease family signature 319 331 3.6E-50 T 11-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AUP74_RS16890 59eb2feddb5e0ec31d81028c4a7f978d 380 PRINTS PR00834 HtrA/DegQ protease family signature 130 150 3.6E-50 T 11-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AUP74_RS16890 59eb2feddb5e0ec31d81028c4a7f978d 380 Gene3D G3DSA:2.30.42.10 282 377 2.1E-26 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS06760 6f12d6f174d57626cddab376fd107ed8 177 Gene3D G3DSA:2.30.30.30 116 176 3.2E-31 T 11-11-2016 IPR014722 Ribosomal protein L2 domain 2 AUP74_RS06760 6f12d6f174d57626cddab376fd107ed8 177 PRINTS PR00338 Transcription termination factor NUSG signature 153 169 2.1E-19 T 11-11-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 AUP74_RS06760 6f12d6f174d57626cddab376fd107ed8 177 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 2.1E-19 T 11-11-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 AUP74_RS06760 6f12d6f174d57626cddab376fd107ed8 177 PRINTS PR00338 Transcription termination factor NUSG signature 135 150 2.1E-19 T 11-11-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 AUP74_RS06760 6f12d6f174d57626cddab376fd107ed8 177 Pfam PF02357 Transcription termination factor nusG 3 108 1.5E-28 T 11-11-2016 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 AUP74_RS06760 6f12d6f174d57626cddab376fd107ed8 177 SMART SM00739 123 150 6.3E-6 T 11-11-2016 IPR005824 KOW AUP74_RS06760 6f12d6f174d57626cddab376fd107ed8 177 Pfam PF00467 KOW motif 126 160 1.4E-7 T 11-11-2016 IPR005824 KOW AUP74_RS06760 6f12d6f174d57626cddab376fd107ed8 177 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 176 1.4E-69 T 11-11-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 AUP74_RS06760 6f12d6f174d57626cddab376fd107ed8 177 SUPERFAMILY SSF50104 121 176 3.56E-19 T 11-11-2016 IPR008991 Translation protein SH3-like domain AUP74_RS06760 6f12d6f174d57626cddab376fd107ed8 177 SUPERFAMILY SSF82679 3 113 9.42E-40 T 11-11-2016 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 AUP74_RS06760 6f12d6f174d57626cddab376fd107ed8 177 ProSitePatterns PS01014 Transcription termination factor nusG signature. 160 169 - T 11-11-2016 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site AUP74_RS06760 6f12d6f174d57626cddab376fd107ed8 177 Gene3D G3DSA:3.30.70.940 3 113 1.2E-44 T 11-11-2016 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 AUP74_RS06760 6f12d6f174d57626cddab376fd107ed8 177 SMART SM00738 2 111 5.1E-50 T 11-11-2016 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 AUP74_RS06760 6f12d6f174d57626cddab376fd107ed8 177 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 177 25.007 T 11-11-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 AUP74_RS01770 96fc3afce541b9b2df3f481522ac4142 869 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 36 867 7.9E-173 T 11-11-2016 IPR010104 Bacterial TonB-dependent receptor AUP74_RS01770 96fc3afce541b9b2df3f481522ac4142 869 SUPERFAMILY SSF56935 500 867 2.62E-88 T 11-11-2016 AUP74_RS01770 96fc3afce541b9b2df3f481522ac4142 869 SUPERFAMILY SSF56935 27 229 2.62E-88 T 11-11-2016 AUP74_RS01770 96fc3afce541b9b2df3f481522ac4142 869 SUPERFAMILY SSF56935 260 461 2.62E-88 T 11-11-2016 AUP74_RS01770 96fc3afce541b9b2df3f481522ac4142 869 Gene3D G3DSA:2.40.170.20 498 867 4.6E-61 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS01770 96fc3afce541b9b2df3f481522ac4142 869 Gene3D G3DSA:2.40.170.20 160 460 4.6E-61 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS01770 96fc3afce541b9b2df3f481522ac4142 869 Pfam PF07715 TonB-dependent Receptor Plug Domain 55 160 2.1E-14 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS01770 96fc3afce541b9b2df3f481522ac4142 869 Pfam PF00593 TonB dependent receptor 595 867 2.0E-28 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS01770 96fc3afce541b9b2df3f481522ac4142 869 Gene3D G3DSA:2.170.130.10 55 159 2.3E-15 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS01770 96fc3afce541b9b2df3f481522ac4142 869 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 44 - T 11-11-2016 IPR010916 TonB box, conserved site AUP74_RS03180 a7538a419c463e41c7750cd8b12fb9db 290 Gene3D G3DSA:3.40.50.720 12 255 1.5E-51 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS03180 a7538a419c463e41c7750cd8b12fb9db 290 SUPERFAMILY SSF51735 17 256 6.4E-51 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS03180 a7538a419c463e41c7750cd8b12fb9db 290 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 102 113 2.4E-5 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS03180 a7538a419c463e41c7750cd8b12fb9db 290 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 163 2.4E-5 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS03180 a7538a419c463e41c7750cd8b12fb9db 290 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 177 196 2.4E-5 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS03180 a7538a419c463e41c7750cd8b12fb9db 290 Pfam PF00106 short chain dehydrogenase 20 209 1.4E-34 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS03180 a7538a419c463e41c7750cd8b12fb9db 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 21 38 5.3E-15 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS03180 a7538a419c463e41c7750cd8b12fb9db 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 102 113 5.3E-15 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS03180 a7538a419c463e41c7750cd8b12fb9db 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 196 5.3E-15 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS03180 a7538a419c463e41c7750cd8b12fb9db 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 165 5.3E-15 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS04320 ea448e7057cadaaa823bc7bf48dc0fff 619 Pfam PF00999 Sodium/hydrogen exchanger family 12 378 5.2E-64 T 11-11-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 AUP74_RS04320 ea448e7057cadaaa823bc7bf48dc0fff 619 Gene3D G3DSA:3.40.50.720 405 540 8.4E-34 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS04320 ea448e7057cadaaa823bc7bf48dc0fff 619 Pfam PF02254 TrkA-N domain 412 525 3.2E-23 T 11-11-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 AUP74_RS04320 ea448e7057cadaaa823bc7bf48dc0fff 619 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 14 289 3.4E-76 T 11-11-2016 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 AUP74_RS04320 ea448e7057cadaaa823bc7bf48dc0fff 619 SUPERFAMILY SSF51735 412 539 3.95E-31 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS08295 f9be61ab26d445c7528930652df74b15 114 SUPERFAMILY SSF50022 2 111 1.57E-22 T 11-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AUP74_RS08295 f9be61ab26d445c7528930652df74b15 114 Gene3D G3DSA:2.102.10.10 1 112 3.9E-22 T 11-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AUP74_RS08295 f9be61ab26d445c7528930652df74b15 114 Pfam PF00355 Rieske [2Fe-2S] domain 4 94 1.8E-13 T 11-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AUP74_RS05985 938e78b11311632584e39b453bc3c2e4 397 SUPERFAMILY SSF51735 2 185 2.67E-19 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS05985 938e78b11311632584e39b453bc3c2e4 397 Gene3D G3DSA:3.40.50.720 1 186 7.7E-34 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS05985 938e78b11311632584e39b453bc3c2e4 397 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 4 133 1.1E-38 T 11-11-2016 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 AUP74_RS05985 938e78b11311632584e39b453bc3c2e4 397 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 137 385 1.3E-37 T 11-11-2016 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 AUP74_RS06485 c50f1e91de2105890517aee2ee265fae 428 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 102 3.0E-34 T 11-11-2016 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AUP74_RS06485 c50f1e91de2105890517aee2ee265fae 428 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 290 297 - T 11-11-2016 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AUP74_RS06485 c50f1e91de2105890517aee2ee265fae 428 Gene3D G3DSA:3.30.1490.20 121 190 4.3E-31 T 11-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 AUP74_RS06485 c50f1e91de2105890517aee2ee265fae 428 Gene3D G3DSA:3.30.470.20 191 328 9.3E-65 T 11-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 AUP74_RS06485 c50f1e91de2105890517aee2ee265fae 428 SMART SM01210 330 423 2.2E-55 T 11-11-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AUP74_RS06485 c50f1e91de2105890517aee2ee265fae 428 SMART SM01209 103 296 2.5E-140 T 11-11-2016 AUP74_RS06485 c50f1e91de2105890517aee2ee265fae 428 SUPERFAMILY SSF51246 329 423 3.92E-34 T 11-11-2016 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AUP74_RS06485 c50f1e91de2105890517aee2ee265fae 428 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 423 6.2E-181 T 11-11-2016 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AUP74_RS06485 c50f1e91de2105890517aee2ee265fae 428 Gene3D G3DSA:3.40.50.20 2 95 1.7E-36 T 11-11-2016 IPR016185 Pre-ATP-grasp domain AUP74_RS06485 c50f1e91de2105890517aee2ee265fae 428 Gene3D G3DSA:3.90.600.10 331 422 8.9E-36 T 11-11-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AUP74_RS06485 c50f1e91de2105890517aee2ee265fae 428 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 331 421 2.6E-31 T 11-11-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AUP74_RS06485 c50f1e91de2105890517aee2ee265fae 428 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 423 43.197 T 11-11-2016 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AUP74_RS06485 c50f1e91de2105890517aee2ee265fae 428 SUPERFAMILY SSF56059 104 324 1.17E-66 T 11-11-2016 AUP74_RS06485 c50f1e91de2105890517aee2ee265fae 428 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 103 296 2.8E-83 T 11-11-2016 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AUP74_RS06485 c50f1e91de2105890517aee2ee265fae 428 SUPERFAMILY SSF52440 1 103 2.16E-35 T 11-11-2016 IPR016185 Pre-ATP-grasp domain AUP74_RS03235 926d22ded2614deeba759f2b026f12e1 214 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 4 209 4.5E-63 T 11-11-2016 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 AUP74_RS03235 926d22ded2614deeba759f2b026f12e1 214 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 3 210 33.911 T 11-11-2016 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 AUP74_RS03235 926d22ded2614deeba759f2b026f12e1 214 Gene3D G3DSA:3.40.50.880 1 210 5.6E-74 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS03235 926d22ded2614deeba759f2b026f12e1 214 PIRSF PIRSF000495 2 212 8.2E-66 T 11-11-2016 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 AUP74_RS03235 926d22ded2614deeba759f2b026f12e1 214 SUPERFAMILY SSF52317 2 210 5.62E-54 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS03235 926d22ded2614deeba759f2b026f12e1 214 Pfam PF00117 Glutamine amidotransferase class-I 6 207 3.8E-19 T 11-11-2016 IPR017926 Glutamine amidotransferase AUP74_RS06040 e65e09d9815dff74814c7daa0c6842c3 269 Gene3D G3DSA:2.160.10.10 143 256 3.8E-28 T 11-11-2016 AUP74_RS06040 e65e09d9815dff74814c7daa0c6842c3 269 Gene3D G3DSA:1.10.3130.10 6 142 1.5E-49 T 11-11-2016 AUP74_RS06040 e65e09d9815dff74814c7daa0c6842c3 269 SMART SM00971 9 113 8.2E-51 T 11-11-2016 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 AUP74_RS06040 e65e09d9815dff74814c7daa0c6842c3 269 SUPERFAMILY SSF51161 7 244 2.63E-61 T 11-11-2016 IPR011004 Trimeric LpxA-like AUP74_RS06040 e65e09d9815dff74814c7daa0c6842c3 269 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 193 227 3.9E-6 T 11-11-2016 IPR001451 Hexapeptide repeat AUP74_RS06040 e65e09d9815dff74814c7daa0c6842c3 269 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 202 230 - T 11-11-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 AUP74_RS06040 e65e09d9815dff74814c7daa0c6842c3 269 Pfam PF06426 Serine acetyltransferase, N-terminal 9 113 2.2E-38 T 11-11-2016 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 AUP74_RS06040 e65e09d9815dff74814c7daa0c6842c3 269 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 82 242 3.2E-68 T 11-11-2016 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 AUP74_RS06425 2cc2f0ad732bfad8396b84580d6b53d1 873 Hamap MF_01411 LPS-assembly protein LptD [lptD]. 10 849 18.896 T 11-11-2016 IPR020889 LPS-assembly protein LptD GO:0009279|GO:0010033|GO:0015920|GO:0043165 AUP74_RS06425 2cc2f0ad732bfad8396b84580d6b53d1 873 Gene3D G3DSA:2.60.450.10 107 260 4.7E-14 T 11-11-2016 AUP74_RS06425 2cc2f0ad732bfad8396b84580d6b53d1 873 Pfam PF04453 Organic solvent tolerance protein 373 777 6.6E-68 T 11-11-2016 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 AUP74_RS06425 2cc2f0ad732bfad8396b84580d6b53d1 873 Pfam PF03968 OstA-like protein 116 242 3.2E-8 T 11-11-2016 IPR005653 Organic solvent tolerance-like, N-terminal AUP74_RS06120 0fdff8b1d64bcd2a3d3a7c3319ddae7e 666 Gene3D G3DSA:3.30.1490.20 129 202 7.6E-27 T 11-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 AUP74_RS06120 0fdff8b1d64bcd2a3d3a7c3319ddae7e 666 SUPERFAMILY SSF51246 331 447 1.88E-41 T 11-11-2016 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AUP74_RS06120 0fdff8b1d64bcd2a3d3a7c3319ddae7e 666 SUPERFAMILY SSF52440 1 113 1.51E-49 T 11-11-2016 IPR016185 Pre-ATP-grasp domain AUP74_RS06120 0fdff8b1d64bcd2a3d3a7c3319ddae7e 666 SUPERFAMILY SSF51230 592 660 1.31E-19 T 11-11-2016 IPR011053 Single hybrid motif AUP74_RS06120 0fdff8b1d64bcd2a3d3a7c3319ddae7e 666 Pfam PF02785 Biotin carboxylase C-terminal domain 336 443 1.7E-39 T 11-11-2016 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AUP74_RS06120 0fdff8b1d64bcd2a3d3a7c3319ddae7e 666 Gene3D G3DSA:3.30.470.20 205 447 4.3E-105 T 11-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 AUP74_RS06120 0fdff8b1d64bcd2a3d3a7c3319ddae7e 666 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 11-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AUP74_RS06120 0fdff8b1d64bcd2a3d3a7c3319ddae7e 666 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 2.3E-45 T 11-11-2016 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AUP74_RS06120 0fdff8b1d64bcd2a3d3a7c3319ddae7e 666 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 617 634 - T 11-11-2016 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AUP74_RS06120 0fdff8b1d64bcd2a3d3a7c3319ddae7e 666 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 11-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AUP74_RS06120 0fdff8b1d64bcd2a3d3a7c3319ddae7e 666 Gene3D G3DSA:2.40.50.100 593 660 7.6E-23 T 11-11-2016 AUP74_RS06120 0fdff8b1d64bcd2a3d3a7c3319ddae7e 666 SMART SM00878 336 443 6.7E-62 T 11-11-2016 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AUP74_RS06120 0fdff8b1d64bcd2a3d3a7c3319ddae7e 666 Pfam PF00364 Biotin-requiring enzyme 595 659 3.8E-15 T 11-11-2016 IPR000089 Biotin/lipoyl attachment AUP74_RS06120 0fdff8b1d64bcd2a3d3a7c3319ddae7e 666 Gene3D G3DSA:3.40.50.20 1 128 1.0E-52 T 11-11-2016 IPR016185 Pre-ATP-grasp domain AUP74_RS06120 0fdff8b1d64bcd2a3d3a7c3319ddae7e 666 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 323 3.0E-70 T 11-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AUP74_RS06120 0fdff8b1d64bcd2a3d3a7c3319ddae7e 666 SUPERFAMILY SSF56059 83 348 8.66E-67 T 11-11-2016 AUP74_RS06890 00cfe0fce0fb526eec5e7823b2cd68b1 101 ProSitePatterns PS00527 Ribosomal protein S14 signature. 62 85 - T 11-11-2016 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06890 00cfe0fce0fb526eec5e7823b2cd68b1 101 SUPERFAMILY SSF57716 2 101 5.27E-38 T 11-11-2016 AUP74_RS06890 00cfe0fce0fb526eec5e7823b2cd68b1 101 Gene3D G3DSA:4.10.830.10 41 101 1.2E-30 T 11-11-2016 AUP74_RS06890 00cfe0fce0fb526eec5e7823b2cd68b1 101 Pfam PF00253 Ribosomal protein S14p/S29e 47 100 4.6E-26 T 11-11-2016 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS06890 00cfe0fce0fb526eec5e7823b2cd68b1 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 26.786 T 11-11-2016 IPR023036 Ribosomal protein S14, bacterial/plastid AUP74_RS01495 e6100a8d68d2bfe3f6b52fb662f6e627 639 Gene3D G3DSA:3.40.50.920 501 624 8.3E-35 T 11-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 AUP74_RS01495 e6100a8d68d2bfe3f6b52fb662f6e627 639 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 18 624 3.6E-261 T 11-11-2016 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AUP74_RS01495 e6100a8d68d2bfe3f6b52fb662f6e627 639 Pfam PF02779 Transketolase, pyrimidine binding domain 325 483 1.2E-36 T 11-11-2016 IPR005475 Transketolase-like, pyrimidine-binding domain AUP74_RS01495 e6100a8d68d2bfe3f6b52fb662f6e627 639 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 15 283 1.7E-118 T 11-11-2016 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AUP74_RS01495 e6100a8d68d2bfe3f6b52fb662f6e627 639 Gene3D G3DSA:3.40.50.970 340 500 1.6E-34 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS01495 e6100a8d68d2bfe3f6b52fb662f6e627 639 SUPERFAMILY SSF52518 244 386 1.85E-76 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS01495 e6100a8d68d2bfe3f6b52fb662f6e627 639 SUPERFAMILY SSF52518 11 200 1.85E-76 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS01495 e6100a8d68d2bfe3f6b52fb662f6e627 639 Gene3D G3DSA:3.40.50.970 243 339 3.0E-74 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS01495 e6100a8d68d2bfe3f6b52fb662f6e627 639 Gene3D G3DSA:3.40.50.970 29 202 3.0E-74 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS01495 e6100a8d68d2bfe3f6b52fb662f6e627 639 SUPERFAMILY SSF52922 497 624 8.38E-32 T 11-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 AUP74_RS01495 e6100a8d68d2bfe3f6b52fb662f6e627 639 ProSitePatterns PS00802 Transketolase signature 2. 430 446 - T 11-11-2016 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AUP74_RS01495 e6100a8d68d2bfe3f6b52fb662f6e627 639 SMART SM00861 324 488 1.1E-63 T 11-11-2016 IPR005475 Transketolase-like, pyrimidine-binding domain AUP74_RS01495 e6100a8d68d2bfe3f6b52fb662f6e627 639 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 14 625 45.309 T 11-11-2016 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AUP74_RS01495 e6100a8d68d2bfe3f6b52fb662f6e627 639 SUPERFAMILY SSF52518 322 509 1.03E-58 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS01495 e6100a8d68d2bfe3f6b52fb662f6e627 639 Pfam PF02780 Transketolase, C-terminal domain 500 616 3.3E-28 T 11-11-2016 IPR033248 Transketolase, C-terminal domain AUP74_RS00370 72b1ca504550055f6758881248b8a461 161 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 113 123 - T 11-11-2016 IPR020549 Endoribonuclease YbeY, conserved site AUP74_RS00370 72b1ca504550055f6758881248b8a461 161 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 5 147 24.263 T 11-11-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 AUP74_RS00370 72b1ca504550055f6758881248b8a461 161 Gene3D G3DSA:3.40.390.30 16 152 2.3E-49 T 11-11-2016 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 AUP74_RS00370 72b1ca504550055f6758881248b8a461 161 SUPERFAMILY SSF55486 5 149 4.88E-48 T 11-11-2016 AUP74_RS00370 72b1ca504550055f6758881248b8a461 161 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 39 143 6.4E-36 T 11-11-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 AUP74_RS00370 72b1ca504550055f6758881248b8a461 161 Pfam PF02130 Uncharacterized protein family UPF0054 19 141 6.9E-38 T 11-11-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 AUP74_RS05055 d1040f5bb9de1e48970cb02c48d6192d 401 Pfam PF10082 Putative beta-barrel porin 2 46 397 3.2E-19 T 11-11-2016 IPR018759 Putative beta-barrel porin 2 AUP74_RS16715 b71af3c43c73ea2bc36e13d130ba694f 400 SMART SM00865 207 331 3.6E-51 T 11-11-2016 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-983189 AUP74_RS16715 b71af3c43c73ea2bc36e13d130ba694f 400 ProSitePatterns PS01134 FtsZ protein signature 1. 44 78 - T 11-11-2016 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 AUP74_RS16715 b71af3c43c73ea2bc36e13d130ba694f 400 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 14 173 2.0E-37 T 11-11-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AUP74_RS16715 b71af3c43c73ea2bc36e13d130ba694f 400 ProSitePatterns PS01135 FtsZ protein signature 2. 97 118 - T 11-11-2016 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 AUP74_RS16715 b71af3c43c73ea2bc36e13d130ba694f 400 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 9 333 8.1E-122 T 11-11-2016 IPR000158 Cell division protein FtsZ GO:0005525 AUP74_RS16715 b71af3c43c73ea2bc36e13d130ba694f 400 SMART SM00864 13 205 2.4E-108 T 11-11-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AUP74_RS16715 b71af3c43c73ea2bc36e13d130ba694f 400 Pfam PF12327 FtsZ family, C-terminal domain 222 322 1.7E-29 T 11-11-2016 IPR024757 Cell division protein FtsZ, C-terminal AUP74_RS16715 b71af3c43c73ea2bc36e13d130ba694f 400 SUPERFAMILY SSF55307 204 325 5.95E-38 T 11-11-2016 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 AUP74_RS16715 b71af3c43c73ea2bc36e13d130ba694f 400 SUPERFAMILY SSF52490 14 205 1.31E-65 T 11-11-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AUP74_RS16715 b71af3c43c73ea2bc36e13d130ba694f 400 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 9 381 36.59 T 11-11-2016 IPR000158 Cell division protein FtsZ GO:0005525 AUP74_RS16715 b71af3c43c73ea2bc36e13d130ba694f 400 PRINTS PR00423 Cell division protein FtsZ signature 126 147 2.4E-48 T 11-11-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AUP74_RS16715 b71af3c43c73ea2bc36e13d130ba694f 400 PRINTS PR00423 Cell division protein FtsZ signature 189 211 2.4E-48 T 11-11-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AUP74_RS16715 b71af3c43c73ea2bc36e13d130ba694f 400 PRINTS PR00423 Cell division protein FtsZ signature 212 233 2.4E-48 T 11-11-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AUP74_RS16715 b71af3c43c73ea2bc36e13d130ba694f 400 PRINTS PR00423 Cell division protein FtsZ signature 98 118 2.4E-48 T 11-11-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AUP74_RS16715 b71af3c43c73ea2bc36e13d130ba694f 400 Gene3D G3DSA:3.30.1330.20 215 325 6.2E-41 T 11-11-2016 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-983189 AUP74_RS16715 b71af3c43c73ea2bc36e13d130ba694f 400 Gene3D G3DSA:3.40.50.1440 14 214 4.4E-88 T 11-11-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AUP74_RS05105 9cccff1467e9fffef7bae2f34c7d68bd 283 Gene3D G3DSA:3.60.110.10 1 282 4.4E-79 T 11-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AUP74_RS05105 9cccff1467e9fffef7bae2f34c7d68bd 283 Pfam PF00795 Carbon-nitrogen hydrolase 6 273 6.5E-47 T 11-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AUP74_RS05105 9cccff1467e9fffef7bae2f34c7d68bd 283 SUPERFAMILY SSF56317 1 278 4.84E-73 T 11-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AUP74_RS10780 8ad07d269deadeb2637baa57ddbffdb3 374 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 153 301 2.9E-13 T 11-11-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AUP74_RS10780 8ad07d269deadeb2637baa57ddbffdb3 374 SUPERFAMILY SSF111369 160 310 1.57E-10 T 11-11-2016 AUP74_RS10780 8ad07d269deadeb2637baa57ddbffdb3 374 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 270 294 4.8E-5 T 11-11-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 AUP74_RS10780 8ad07d269deadeb2637baa57ddbffdb3 374 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 347 362 4.8E-5 T 11-11-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 AUP74_RS10780 8ad07d269deadeb2637baa57ddbffdb3 374 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 54 74 4.8E-5 T 11-11-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 AUP74_RS10780 8ad07d269deadeb2637baa57ddbffdb3 374 SUPERFAMILY SSF111369 42 124 6.41E-11 T 11-11-2016 AUP74_RS10780 8ad07d269deadeb2637baa57ddbffdb3 374 Gene3D G3DSA:2.40.50.100 45 76 1.6E-16 T 11-11-2016 AUP74_RS10780 8ad07d269deadeb2637baa57ddbffdb3 374 Gene3D G3DSA:2.40.50.100 224 257 1.6E-16 T 11-11-2016 AUP74_RS10780 8ad07d269deadeb2637baa57ddbffdb3 374 Pfam PF13533 Biotin-lipoyl like 43 88 2.9E-11 T 11-11-2016 AUP74_RS13615 84b59078f5a7985611024c4fee034962 353 Gene3D G3DSA:3.40.50.720 166 286 6.0E-33 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS13615 84b59078f5a7985611024c4fee034962 353 SMART SM00829 7 338 0.0022 T 11-11-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AUP74_RS13615 84b59078f5a7985611024c4fee034962 353 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 23 101 2.8E-12 T 11-11-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AUP74_RS13615 84b59078f5a7985611024c4fee034962 353 SUPERFAMILY SSF51735 138 305 5.38E-32 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS13615 84b59078f5a7985611024c4fee034962 353 Pfam PF00107 Zinc-binding dehydrogenase 174 301 2.1E-19 T 11-11-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AUP74_RS13615 84b59078f5a7985611024c4fee034962 353 Gene3D G3DSA:3.90.180.10 5 165 2.0E-32 T 11-11-2016 IPR011032 GroES-like AUP74_RS13615 84b59078f5a7985611024c4fee034962 353 SUPERFAMILY SSF50129 6 180 6.85E-35 T 11-11-2016 IPR011032 GroES-like AUP74_RS14555 ac0697c1145262ae2a3b68d78bbc1958 249 SUPERFAMILY SSF53474 62 217 8.87E-20 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS14555 ac0697c1145262ae2a3b68d78bbc1958 249 Gene3D G3DSA:3.40.50.1820 67 214 5.8E-13 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS14555 ac0697c1145262ae2a3b68d78bbc1958 249 Pfam PF12695 Alpha/beta hydrolase family 68 237 5.8E-41 T 11-11-2016 IPR029059 Alpha/beta hydrolase fold-5 AUP74_RS15735 7fcd9172cf57b317c2d762b45287f3b7 379 Pfam PF04079 Segregation and condensation complex subunit ScpB 10 171 9.7E-54 T 11-11-2016 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 AUP74_RS15735 7fcd9172cf57b317c2d762b45287f3b7 379 SUPERFAMILY SSF46785 86 162 1.41E-26 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS15735 7fcd9172cf57b317c2d762b45287f3b7 379 Gene3D G3DSA:1.10.10.10 5 84 1.3E-19 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS15735 7fcd9172cf57b317c2d762b45287f3b7 379 Gene3D G3DSA:1.10.10.10 86 162 1.2E-36 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS15735 7fcd9172cf57b317c2d762b45287f3b7 379 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 8 175 3.3E-37 T 11-11-2016 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 AUP74_RS15735 7fcd9172cf57b317c2d762b45287f3b7 379 SUPERFAMILY SSF46785 8 85 1.04E-15 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS06935 30399165f72830ca011a9c61c4f67f34 118 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 11-11-2016 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06935 30399165f72830ca011a9c61c4f67f34 118 Pfam PF00416 Ribosomal protein S13/S18 3 108 1.1E-30 T 11-11-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06935 30399165f72830ca011a9c61c4f67f34 118 PIRSF PIRSF002134 1 118 1.8E-39 T 11-11-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06935 30399165f72830ca011a9c61c4f67f34 118 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 3.3E-52 T 11-11-2016 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS06935 30399165f72830ca011a9c61c4f67f34 118 SUPERFAMILY SSF46946 2 114 7.51E-44 T 11-11-2016 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 AUP74_RS06935 30399165f72830ca011a9c61c4f67f34 118 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 118 25.05 T 11-11-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06935 30399165f72830ca011a9c61c4f67f34 118 Gene3D G3DSA:1.10.8.50 1 71 1.7E-28 T 11-11-2016 AUP74_RS06935 30399165f72830ca011a9c61c4f67f34 118 Gene3D G3DSA:4.10.910.10 72 118 1.7E-25 T 11-11-2016 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS04595 7384fb62fbeed56233d8e731d689dbd6 301 PIRSF PIRSF000166 2 301 1.7E-126 T 11-11-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AUP74_RS04595 7384fb62fbeed56233d8e731d689dbd6 301 Pfam PF01218 Coproporphyrinogen III oxidase 9 301 2.2E-132 T 11-11-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AUP74_RS04595 7384fb62fbeed56233d8e731d689dbd6 301 Gene3D G3DSA:3.40.1500.10 5 301 1.2E-134 T 11-11-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AUP74_RS04595 7384fb62fbeed56233d8e731d689dbd6 301 ProSitePatterns PS01021 Coproporphyrinogen III oxidase signature. 165 189 - T 11-11-2016 IPR018375 Coproporphyrinogen III oxidase, conserved site GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AUP74_RS04595 7384fb62fbeed56233d8e731d689dbd6 301 SUPERFAMILY SSF102886 5 301 3.53E-138 T 11-11-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AUP74_RS04595 7384fb62fbeed56233d8e731d689dbd6 301 Hamap MF_00333 Oxygen-dependent coproporphyrinogen-III oxidase [hemF]. 3 276 57.133 T 11-11-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AUP74_RS04595 7384fb62fbeed56233d8e731d689dbd6 301 PRINTS PR00073 Coprogen oxidase signature 30 46 2.1E-87 T 11-11-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AUP74_RS04595 7384fb62fbeed56233d8e731d689dbd6 301 PRINTS PR00073 Coprogen oxidase signature 261 287 2.1E-87 T 11-11-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AUP74_RS04595 7384fb62fbeed56233d8e731d689dbd6 301 PRINTS PR00073 Coprogen oxidase signature 47 68 2.1E-87 T 11-11-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AUP74_RS04595 7384fb62fbeed56233d8e731d689dbd6 301 PRINTS PR00073 Coprogen oxidase signature 161 190 2.1E-87 T 11-11-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AUP74_RS04595 7384fb62fbeed56233d8e731d689dbd6 301 PRINTS PR00073 Coprogen oxidase signature 233 260 2.1E-87 T 11-11-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AUP74_RS04595 7384fb62fbeed56233d8e731d689dbd6 301 PRINTS PR00073 Coprogen oxidase signature 124 146 2.1E-87 T 11-11-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AUP74_RS04595 7384fb62fbeed56233d8e731d689dbd6 301 PRINTS PR00073 Coprogen oxidase signature 89 113 2.1E-87 T 11-11-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AUP74_RS09325 5f55c348dd57b3a2b93bac75e1fd93dd 488 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 342 349 - T 11-11-2016 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 AUP74_RS09325 5f55c348dd57b3a2b93bac75e1fd93dd 488 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 3 488 35.826 T 11-11-2016 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 AUP74_RS09325 5f55c348dd57b3a2b93bac75e1fd93dd 488 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 179 481 1.7E-124 T 11-11-2016 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 AUP74_RS09325 5f55c348dd57b3a2b93bac75e1fd93dd 488 Gene3D G3DSA:3.40.220.10 1 153 2.0E-31 T 11-11-2016 AUP74_RS09325 5f55c348dd57b3a2b93bac75e1fd93dd 488 PRINTS PR00481 Cytosol aminopeptidase signature 257 274 2.3E-55 T 11-11-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 AUP74_RS09325 5f55c348dd57b3a2b93bac75e1fd93dd 488 PRINTS PR00481 Cytosol aminopeptidase signature 316 337 2.3E-55 T 11-11-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 AUP74_RS09325 5f55c348dd57b3a2b93bac75e1fd93dd 488 PRINTS PR00481 Cytosol aminopeptidase signature 366 381 2.3E-55 T 11-11-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 AUP74_RS09325 5f55c348dd57b3a2b93bac75e1fd93dd 488 PRINTS PR00481 Cytosol aminopeptidase signature 338 358 2.3E-55 T 11-11-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 AUP74_RS09325 5f55c348dd57b3a2b93bac75e1fd93dd 488 PRINTS PR00481 Cytosol aminopeptidase signature 279 300 2.3E-55 T 11-11-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 AUP74_RS09325 5f55c348dd57b3a2b93bac75e1fd93dd 488 Gene3D G3DSA:3.40.630.10 175 487 1.1E-143 T 11-11-2016 AUP74_RS09325 5f55c348dd57b3a2b93bac75e1fd93dd 488 SUPERFAMILY SSF52949 1 173 3.12E-23 T 11-11-2016 AUP74_RS09325 5f55c348dd57b3a2b93bac75e1fd93dd 488 SUPERFAMILY SSF53187 174 487 2.13E-126 T 11-11-2016 AUP74_RS09325 5f55c348dd57b3a2b93bac75e1fd93dd 488 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 19 141 2.9E-15 T 11-11-2016 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 AUP74_RS07340 0db80fd27e9403645462f9ed2184a4aa 459 Pfam PF01554 MatE 25 185 1.3E-26 T 11-11-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AUP74_RS07340 0db80fd27e9403645462f9ed2184a4aa 459 Pfam PF01554 MatE 250 411 5.5E-22 T 11-11-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AUP74_RS07340 0db80fd27e9403645462f9ed2184a4aa 459 TIGRFAM TIGR00797 matE: MATE efflux family protein 25 413 3.8E-58 T 11-11-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AUP74_RS07340 0db80fd27e9403645462f9ed2184a4aa 459 PIRSF PIRSF006603 3 455 2.0E-105 T 11-11-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AUP74_RS04055 b349e94d72abcaf455967cbba8c2ba95 417 SUPERFAMILY SSF51230 196 262 7.85E-9 T 11-11-2016 IPR011053 Single hybrid motif AUP74_RS04055 b349e94d72abcaf455967cbba8c2ba95 417 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 229 330 2.0E-11 T 11-11-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AUP74_RS04055 b349e94d72abcaf455967cbba8c2ba95 417 Gene3D G3DSA:2.40.50.100 190 252 4.0E-10 T 11-11-2016 AUP74_RS08270 f288d6a9c4a3dcc60973bcf66a454833 462 Pfam PF00072 Response regulator receiver domain 4 109 4.7E-21 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS08270 f288d6a9c4a3dcc60973bcf66a454833 462 Gene3D G3DSA:3.40.50.300 134 308 7.8E-61 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS08270 f288d6a9c4a3dcc60973bcf66a454833 462 SUPERFAMILY SSF52540 136 375 7.9E-73 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS08270 f288d6a9c4a3dcc60973bcf66a454833 462 Gene3D G3DSA:1.10.10.60 362 450 2.8E-9 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS08270 f288d6a9c4a3dcc60973bcf66a454833 462 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 222 237 - T 11-11-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 AUP74_RS08270 f288d6a9c4a3dcc60973bcf66a454833 462 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 160 173 - T 11-11-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 AUP74_RS08270 f288d6a9c4a3dcc60973bcf66a454833 462 SUPERFAMILY SSF52172 2 180 1.57E-38 T 11-11-2016 IPR011006 CheY-like superfamily AUP74_RS08270 f288d6a9c4a3dcc60973bcf66a454833 462 Pfam PF00158 Sigma-54 interaction domain 136 302 6.9E-72 T 11-11-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 AUP74_RS08270 f288d6a9c4a3dcc60973bcf66a454833 462 SMART SM00382 156 299 2.4E-13 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS08270 f288d6a9c4a3dcc60973bcf66a454833 462 Gene3D G3DSA:1.10.8.60 309 361 2.4E-21 T 11-11-2016 AUP74_RS08270 f288d6a9c4a3dcc60973bcf66a454833 462 SMART SM00448 2 109 6.0E-28 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS08270 f288d6a9c4a3dcc60973bcf66a454833 462 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 349 358 - T 11-11-2016 IPR025944 Sigma-54 interaction domain, conserved site AUP74_RS08270 f288d6a9c4a3dcc60973bcf66a454833 462 Gene3D G3DSA:3.40.50.2300 1 121 1.4E-30 T 11-11-2016 AUP74_RS06315 3af46913b4c5e980a67214352863657a 666 SMART SM00493 269 340 3.6E-18 T 11-11-2016 IPR006171 Toprim domain AUP74_RS06315 3af46913b4c5e980a67214352863657a 666 SUPERFAMILY SSF57783 5 101 7.82E-37 T 11-11-2016 AUP74_RS06315 3af46913b4c5e980a67214352863657a 666 Gene3D G3DSA:3.90.580.10 2 101 1.5E-41 T 11-11-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 AUP74_RS06315 3af46913b4c5e980a67214352863657a 666 Hamap MF_00974 DNA primase [dnaG]. 4 644 29.063 T 11-11-2016 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 AUP74_RS06315 3af46913b4c5e980a67214352863657a 666 Pfam PF13662 Toprim domain 270 337 4.5E-16 T 11-11-2016 IPR006171 Toprim domain AUP74_RS06315 3af46913b4c5e980a67214352863657a 666 Gene3D G3DSA:3.90.980.10 115 250 6.9E-46 T 11-11-2016 IPR013264 DNA primase, catalytic core, N-terminal AUP74_RS06315 3af46913b4c5e980a67214352863657a 666 TIGRFAM TIGR01391 dnaG: DNA primase 5 428 3.2E-141 T 11-11-2016 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 AUP74_RS06315 3af46913b4c5e980a67214352863657a 666 SUPERFAMILY SSF117023 523 660 2.88E-17 T 11-11-2016 AUP74_RS06315 3af46913b4c5e980a67214352863657a 666 Gene3D G3DSA:3.40.1360.10 251 375 1.8E-44 T 11-11-2016 AUP74_RS06315 3af46913b4c5e980a67214352863657a 666 Pfam PF08275 DNA primase catalytic core, N-terminal domain 126 261 1.8E-38 T 11-11-2016 IPR013264 DNA primase, catalytic core, N-terminal AUP74_RS06315 3af46913b4c5e980a67214352863657a 666 Pfam PF08278 DNA primase DnaG DnaB-binding 522 658 6.7E-20 T 11-11-2016 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 AUP74_RS06315 3af46913b4c5e980a67214352863657a 666 Gene3D G3DSA:1.20.50.20 379 436 5.7E-20 T 11-11-2016 AUP74_RS06315 3af46913b4c5e980a67214352863657a 666 SMART SM00766 521 662 4.2E-11 T 11-11-2016 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 AUP74_RS06315 3af46913b4c5e980a67214352863657a 666 Gene3D G3DSA:1.10.860.10 510 661 8.3E-23 T 11-11-2016 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal AUP74_RS06315 3af46913b4c5e980a67214352863657a 666 Pfam PF10410 DnaB-helicase binding domain of primase 381 434 2.2E-11 T 11-11-2016 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 AUP74_RS06315 3af46913b4c5e980a67214352863657a 666 PIRSF PIRSF002811 2 659 8.5E-145 T 11-11-2016 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 AUP74_RS06315 3af46913b4c5e980a67214352863657a 666 SMART SM00400 36 90 4.0E-36 T 11-11-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 AUP74_RS06315 3af46913b4c5e980a67214352863657a 666 Pfam PF01807 CHC2 zinc finger 6 100 2.2E-40 T 11-11-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 AUP74_RS06315 3af46913b4c5e980a67214352863657a 666 SUPERFAMILY SSF56731 115 434 1.96E-104 T 11-11-2016 AUP74_RS00160 b04040a63f7cbdb6705567364706e2c9 361 SMART SM00937 67 180 1.9E-69 T 11-11-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 AUP74_RS00160 b04040a63f7cbdb6705567364706e2c9 361 Gene3D G3DSA:1.20.58.410 8 95 7.4E-23 T 11-11-2016 AUP74_RS00160 b04040a63f7cbdb6705567364706e2c9 361 SUPERFAMILY SSF75620 12 355 4.84E-138 T 11-11-2016 AUP74_RS00160 b04040a63f7cbdb6705567364706e2c9 361 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 5 359 41.866 T 11-11-2016 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 AUP74_RS00160 b04040a63f7cbdb6705567364706e2c9 361 Gene3D G3DSA:3.30.160.20 214 289 1.8E-36 T 11-11-2016 IPR014720 Double-stranded RNA-binding domain AUP74_RS00160 b04040a63f7cbdb6705567364706e2c9 361 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 1 358 6.6E-173 T 11-11-2016 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 AUP74_RS00160 b04040a63f7cbdb6705567364706e2c9 361 Pfam PF00472 RF-1 domain 215 323 1.0E-42 T 11-11-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 AUP74_RS00160 b04040a63f7cbdb6705567364706e2c9 361 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 230 246 - T 11-11-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 AUP74_RS00160 b04040a63f7cbdb6705567364706e2c9 361 Pfam PF03462 PCRF domain 13 205 1.6E-76 T 11-11-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 AUP74_RS06715 0ce8773952e3573f5a6183ab91b25ba7 243 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 243 17.051 T 11-11-2016 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 AUP74_RS06715 0ce8773952e3573f5a6183ab91b25ba7 243 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 89 239 5.6E-26 T 11-11-2016 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 AUP74_RS06715 0ce8773952e3573f5a6183ab91b25ba7 243 Pfam PF03309 Type III pantothenate kinase 2 198 1.2E-40 T 11-11-2016 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 AUP74_RS06715 0ce8773952e3573f5a6183ab91b25ba7 243 SUPERFAMILY SSF53067 115 240 7.45E-27 T 11-11-2016 AUP74_RS06715 0ce8773952e3573f5a6183ab91b25ba7 243 Gene3D G3DSA:3.30.420.40 86 240 1.0E-39 T 11-11-2016 AUP74_RS06715 0ce8773952e3573f5a6183ab91b25ba7 243 SUPERFAMILY SSF53067 1 112 7.77E-21 T 11-11-2016 AUP74_RS14530 dd2e2e24d03497d428a66bac7eb4657e 427 Gene3D G3DSA:2.40.110.10 156 239 8.3E-22 T 11-11-2016 AUP74_RS14530 dd2e2e24d03497d428a66bac7eb4657e 427 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 151 237 6.5E-13 T 11-11-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 AUP74_RS14530 dd2e2e24d03497d428a66bac7eb4657e 427 SUPERFAMILY SSF47203 271 404 1.13E-9 T 11-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AUP74_RS14530 dd2e2e24d03497d428a66bac7eb4657e 427 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 16 105 7.7E-11 T 11-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 AUP74_RS14530 dd2e2e24d03497d428a66bac7eb4657e 427 SUPERFAMILY SSF56645 16 246 5.5E-38 T 11-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 AUP74_RS14530 dd2e2e24d03497d428a66bac7eb4657e 427 Gene3D G3DSA:1.10.540.10 13 101 8.6E-17 T 11-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 AUP74_RS14530 dd2e2e24d03497d428a66bac7eb4657e 427 Gene3D G3DSA:1.20.140.10 240 405 1.5E-12 T 11-11-2016 AUP74_RS14530 dd2e2e24d03497d428a66bac7eb4657e 427 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 276 378 5.8E-5 T 11-11-2016 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain AUP74_RS03120 66368042770d001793d75e5bb3d7c975 139 SUPERFAMILY SSF54637 20 131 1.07E-26 T 11-11-2016 IPR029069 HotDog domain AUP74_RS03120 66368042770d001793d75e5bb3d7c975 139 Pfam PF01575 MaoC like domain 16 116 1.8E-24 T 11-11-2016 IPR002539 MaoC-like domain AUP74_RS03120 66368042770d001793d75e5bb3d7c975 139 Gene3D G3DSA:3.10.129.10 7 131 1.0E-33 T 11-11-2016 IPR029069 HotDog domain AUP74_RS03120 66368042770d001793d75e5bb3d7c975 139 PRINTS PR01483 Fatty acid synthase signature 25 47 7.0E-6 T 11-11-2016 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 AUP74_RS03120 66368042770d001793d75e5bb3d7c975 139 PRINTS PR01483 Fatty acid synthase signature 47 68 7.0E-6 T 11-11-2016 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 AUP74_RS06830 82b8b35a9ae7835fc9134447fc09d9dd 204 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 204 34.358 T 11-11-2016 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06830 82b8b35a9ae7835fc9134447fc09d9dd 204 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 16 201 4.3E-76 T 11-11-2016 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06830 82b8b35a9ae7835fc9134447fc09d9dd 204 SUPERFAMILY SSF52166 8 203 1.09E-74 T 11-11-2016 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 AUP74_RS06830 82b8b35a9ae7835fc9134447fc09d9dd 204 Gene3D G3DSA:3.40.1370.10 56 203 3.0E-60 T 11-11-2016 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 AUP74_RS06830 82b8b35a9ae7835fc9134447fc09d9dd 204 Pfam PF00573 Ribosomal protein L4/L1 family 15 201 1.7E-64 T 11-11-2016 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 AUP74_RS10920 6500883436c7d090eb1f3e92b35b7f8e 363 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 45 153 6.4E-14 T 11-11-2016 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 AUP74_RS10920 6500883436c7d090eb1f3e92b35b7f8e 363 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 223 334 4.0E-13 T 11-11-2016 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 AUP74_RS10920 6500883436c7d090eb1f3e92b35b7f8e 363 Pfam PF03061 Thioesterase superfamily 71 148 5.2E-7 T 11-11-2016 IPR006683 Thioesterase domain Reactome: R-HSA-75105 AUP74_RS10920 6500883436c7d090eb1f3e92b35b7f8e 363 Pfam PF03061 Thioesterase superfamily 251 326 3.1E-7 T 11-11-2016 IPR006683 Thioesterase domain Reactome: R-HSA-75105 AUP74_RS10920 6500883436c7d090eb1f3e92b35b7f8e 363 SUPERFAMILY SSF54637 15 155 7.66E-22 T 11-11-2016 IPR029069 HotDog domain AUP74_RS10920 6500883436c7d090eb1f3e92b35b7f8e 363 Gene3D G3DSA:3.10.129.10 33 159 7.7E-24 T 11-11-2016 IPR029069 HotDog domain AUP74_RS10920 6500883436c7d090eb1f3e92b35b7f8e 363 Gene3D G3DSA:3.10.129.10 215 336 1.5E-21 T 11-11-2016 IPR029069 HotDog domain AUP74_RS10920 6500883436c7d090eb1f3e92b35b7f8e 363 SUPERFAMILY SSF54637 211 332 2.83E-21 T 11-11-2016 IPR029069 HotDog domain AUP74_RS09310 09c9d15f530f5091a1562e2bfe0643a2 923 SUPERFAMILY SSF52374 578 610 9.81E-137 T 11-11-2016 AUP74_RS09310 09c9d15f530f5091a1562e2bfe0643a2 923 SUPERFAMILY SSF52374 1 191 9.81E-137 T 11-11-2016 AUP74_RS09310 09c9d15f530f5091a1562e2bfe0643a2 923 SUPERFAMILY SSF52374 340 540 9.81E-137 T 11-11-2016 AUP74_RS09310 09c9d15f530f5091a1562e2bfe0643a2 923 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 53 - T 11-11-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS09310 09c9d15f530f5091a1562e2bfe0643a2 923 Gene3D G3DSA:3.90.740.10 193 336 1.3E-52 T 11-11-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AUP74_RS09310 09c9d15f530f5091a1562e2bfe0643a2 923 SUPERFAMILY SSF50677 189 341 1.57E-66 T 11-11-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AUP74_RS09310 09c9d15f530f5091a1562e2bfe0643a2 923 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 13 600 9.5E-222 T 11-11-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS09310 09c9d15f530f5091a1562e2bfe0643a2 923 Gene3D G3DSA:1.10.287.380 849 920 1.5E-10 T 11-11-2016 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 AUP74_RS09310 09c9d15f530f5091a1562e2bfe0643a2 923 Gene3D G3DSA:3.40.50.620 3 192 5.2E-143 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS09310 09c9d15f530f5091a1562e2bfe0643a2 923 Gene3D G3DSA:3.40.50.620 578 599 5.2E-143 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS09310 09c9d15f530f5091a1562e2bfe0643a2 923 Gene3D G3DSA:3.40.50.620 340 540 5.2E-143 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS09310 09c9d15f530f5091a1562e2bfe0643a2 923 PRINTS PR00986 Valyl-tRNA synthetase signature 229 246 2.0E-37 T 11-11-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AUP74_RS09310 09c9d15f530f5091a1562e2bfe0643a2 923 PRINTS PR00986 Valyl-tRNA synthetase signature 444 465 2.0E-37 T 11-11-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AUP74_RS09310 09c9d15f530f5091a1562e2bfe0643a2 923 PRINTS PR00986 Valyl-tRNA synthetase signature 345 358 2.0E-37 T 11-11-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AUP74_RS09310 09c9d15f530f5091a1562e2bfe0643a2 923 PRINTS PR00986 Valyl-tRNA synthetase signature 475 493 2.0E-37 T 11-11-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AUP74_RS09310 09c9d15f530f5091a1562e2bfe0643a2 923 PRINTS PR00986 Valyl-tRNA synthetase signature 35 46 2.0E-37 T 11-11-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AUP74_RS09310 09c9d15f530f5091a1562e2bfe0643a2 923 TIGRFAM TIGR00422 valS: valine--tRNA ligase 1 902 0.0 T 11-11-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AUP74_RS09310 09c9d15f530f5091a1562e2bfe0643a2 923 Pfam PF08264 Anticodon-binding domain of tRNA 644 794 7.3E-47 T 11-11-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 AUP74_RS09310 09c9d15f530f5091a1562e2bfe0643a2 923 SUPERFAMILY SSF47323 611 871 6.73E-72 T 11-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS09310 09c9d15f530f5091a1562e2bfe0643a2 923 Hamap MF_02004 Valine--tRNA ligase [valS]. 1 921 16.219 T 11-11-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AUP74_RS09310 09c9d15f530f5091a1562e2bfe0643a2 923 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 856 920 8.4E-21 T 11-11-2016 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 AUP74_RS09310 09c9d15f530f5091a1562e2bfe0643a2 923 SUPERFAMILY SSF46589 856 920 2.88E-17 T 11-11-2016 IPR010978 tRNA-binding arm GO:0000166 AUP74_RS09310 09c9d15f530f5091a1562e2bfe0643a2 923 Gene3D G3DSA:1.10.730.10 600 788 7.1E-68 T 11-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS07715 6f157032c41805dca6a6133523dc1190 690 Hamap MF_00461 Electron transport complex subunit RsxC [rsxC]. 1 690 188.467 T 11-11-2016 IPR010208 Electron transport complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 AUP74_RS07715 6f157032c41805dca6a6133523dc1190 690 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 130 276 1.3E-48 T 11-11-2016 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS07715 6f157032c41805dca6a6133523dc1190 690 SUPERFAMILY SSF46548 326 435 2.09E-19 T 11-11-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 AUP74_RS07715 6f157032c41805dca6a6133523dc1190 690 Gene3D G3DSA:1.10.1060.10 351 441 1.8E-18 T 11-11-2016 AUP74_RS07715 6f157032c41805dca6a6133523dc1190 690 TIGRFAM TIGR01945 rnfC: electron transport complex, RnfABCDGE type, C subunit 5 436 2.4E-183 T 11-11-2016 IPR010208 Electron transport complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 AUP74_RS07715 6f157032c41805dca6a6133523dc1190 690 SUPERFAMILY SSF142019 85 294 1.18E-58 T 11-11-2016 AUP74_RS07715 6f157032c41805dca6a6133523dc1190 690 Pfam PF13375 RnfC Barrel sandwich hybrid domain 5 106 4.9E-36 T 11-11-2016 IPR026902 RnfC Barrel sandwich hybrid domain AUP74_RS07715 6f157032c41805dca6a6133523dc1190 690 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 408 419 - T 11-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AUP74_RS07715 6f157032c41805dca6a6133523dc1190 690 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 369 380 - T 11-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AUP74_RS07715 6f157032c41805dca6a6133523dc1190 690 Pfam PF13237 4Fe-4S dicluster domain 367 419 8.6E-9 T 11-11-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AUP74_RS15815 da8d065c01bf3fb49c910b752f2b6325 778 Gene3D G3DSA:3.40.190.10 388 484 5.9E-8 T 11-11-2016 AUP74_RS15815 da8d065c01bf3fb49c910b752f2b6325 778 Pfam PF01464 Transglycosylase SLT domain 559 665 7.9E-26 T 11-11-2016 IPR008258 Transglycosylase SLT domain 1 AUP74_RS15815 da8d065c01bf3fb49c910b752f2b6325 778 Gene3D G3DSA:3.40.190.10 109 197 9.4E-10 T 11-11-2016 AUP74_RS15815 da8d065c01bf3fb49c910b752f2b6325 778 SUPERFAMILY SSF53850 308 536 6.21E-35 T 11-11-2016 AUP74_RS15815 da8d065c01bf3fb49c910b752f2b6325 778 Gene3D G3DSA:1.10.530.10 554 736 4.4E-45 T 11-11-2016 AUP74_RS15815 da8d065c01bf3fb49c910b752f2b6325 778 Gene3D G3DSA:3.40.190.10 495 535 1.7E-16 T 11-11-2016 AUP74_RS15815 da8d065c01bf3fb49c910b752f2b6325 778 Gene3D G3DSA:3.40.190.10 309 387 1.7E-16 T 11-11-2016 AUP74_RS15815 da8d065c01bf3fb49c910b752f2b6325 778 SMART SM00062 312 536 1.7E-27 T 11-11-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AUP74_RS15815 da8d065c01bf3fb49c910b752f2b6325 778 SUPERFAMILY SSF53850 109 291 2.09E-16 T 11-11-2016 AUP74_RS15815 da8d065c01bf3fb49c910b752f2b6325 778 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 109 291 1.3E-13 T 11-11-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AUP74_RS15815 da8d065c01bf3fb49c910b752f2b6325 778 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 324 534 4.2E-29 T 11-11-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AUP74_RS15815 da8d065c01bf3fb49c910b752f2b6325 778 SUPERFAMILY SSF53955 555 731 1.42E-40 T 11-11-2016 IPR023346 Lysozyme-like domain AUP74_RS05775 131f62689c8d07c32ee292c0267b5d17 456 Gene3D G3DSA:1.10.3210.10 171 288 9.9E-8 T 11-11-2016 IPR006674 HD domain AUP74_RS05775 131f62689c8d07c32ee292c0267b5d17 456 SUPERFAMILY SSF109604 168 336 1.31E-14 T 11-11-2016 AUP74_RS05775 131f62689c8d07c32ee292c0267b5d17 456 Pfam PF11871 Domain of unknown function (DUF3391) 7 146 1.7E-20 T 11-11-2016 IPR021812 Protein of unknown function DUF3391 AUP74_RS05775 131f62689c8d07c32ee292c0267b5d17 456 Pfam PF13487 HD domain 238 294 2.8E-13 T 11-11-2016 AUP74_RS14025 6ee8a74543de144394468244a95c9502 254 SUPERFAMILY SSF88713 2 244 8.15E-91 T 11-11-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AUP74_RS14025 6ee8a74543de144394468244a95c9502 254 Pfam PF03746 LamB/YcsF family 2 242 1.1E-96 T 11-11-2016 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF AUP74_RS09405 d0905311dd774b91e7aba75afd5768a5 346 Gene3D G3DSA:3.40.1780.10 176 337 1.4E-103 T 11-11-2016 AUP74_RS09405 d0905311dd774b91e7aba75afd5768a5 346 Gene3D G3DSA:3.40.1780.10 1 62 1.4E-103 T 11-11-2016 AUP74_RS09405 d0905311dd774b91e7aba75afd5768a5 346 SUPERFAMILY SSF111337 4 337 3.4E-138 T 11-11-2016 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 AUP74_RS09405 d0905311dd774b91e7aba75afd5768a5 346 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 337 6.8E-148 T 11-11-2016 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 AUP74_RS09405 d0905311dd774b91e7aba75afd5768a5 346 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 338 47.767 T 11-11-2016 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 AUP74_RS09405 d0905311dd774b91e7aba75afd5768a5 346 Pfam PF02547 Queuosine biosynthesis protein 4 337 2.0E-136 T 11-11-2016 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 AUP74_RS09405 d0905311dd774b91e7aba75afd5768a5 346 Gene3D G3DSA:2.40.10.240 64 134 2.3E-17 T 11-11-2016 AUP74_RS00430 b62339de71002ba6588ebd1d62824be9 553 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 189 201 - T 11-11-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AUP74_RS00430 b62339de71002ba6588ebd1d62824be9 553 SUPERFAMILY SSF56645 75 300 1.44E-34 T 11-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 AUP74_RS00430 b62339de71002ba6588ebd1d62824be9 553 Gene3D G3DSA:2.40.110.10 187 284 1.2E-19 T 11-11-2016 AUP74_RS00430 b62339de71002ba6588ebd1d62824be9 553 Gene3D G3DSA:1.20.140.10 285 449 5.1E-39 T 11-11-2016 AUP74_RS00430 b62339de71002ba6588ebd1d62824be9 553 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 404 423 - T 11-11-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AUP74_RS00430 b62339de71002ba6588ebd1d62824be9 553 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 187 279 1.6E-15 T 11-11-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 AUP74_RS00430 b62339de71002ba6588ebd1d62824be9 553 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 291 445 7.8E-29 T 11-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AUP74_RS00430 b62339de71002ba6588ebd1d62824be9 553 SUPERFAMILY SSF47203 297 448 1.53E-37 T 11-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AUP74_RS09940 f384b58e69905d21adb5be4a07fe4196 250 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 1 233 2.8E-68 T 11-11-2016 AUP74_RS09940 f384b58e69905d21adb5be4a07fe4196 250 Gene3D G3DSA:3.40.190.10 101 195 2.6E-15 T 11-11-2016 AUP74_RS09940 f384b58e69905d21adb5be4a07fe4196 250 SUPERFAMILY SSF53850 19 207 9.02E-47 T 11-11-2016 AUP74_RS09940 f384b58e69905d21adb5be4a07fe4196 250 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 1 216 4.7E-71 T 11-11-2016 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 AUP74_RS09940 f384b58e69905d21adb5be4a07fe4196 250 Gene3D G3DSA:3.40.190.10 17 100 6.1E-5 T 11-11-2016 AUP74_RS06350 3388cfba22226a42c92c00c26909bbfb 367 Gene3D G3DSA:3.40.50.880 43 282 2.3E-70 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS06350 3388cfba22226a42c92c00c26909bbfb 367 SUPERFAMILY SSF52317 58 279 5.32E-56 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS06350 3388cfba22226a42c92c00c26909bbfb 367 Pfam PF01965 DJ-1/PfpI family 77 277 4.3E-10 T 11-11-2016 IPR002818 DJ-1/PfpI AUP74_RS04395 c2a09156343be52ded1d897f85205510 286 Gene3D G3DSA:1.10.287.80 235 281 7.9E-32 T 11-11-2016 AUP74_RS04395 c2a09156343be52ded1d897f85205510 286 Gene3D G3DSA:1.10.287.80 19 60 2.1E-38 T 11-11-2016 AUP74_RS04395 c2a09156343be52ded1d897f85205510 286 Gene3D G3DSA:1.10.287.80 201 234 2.1E-38 T 11-11-2016 AUP74_RS04395 c2a09156343be52ded1d897f85205510 286 SUPERFAMILY SSF52943 3 286 9.42E-94 T 11-11-2016 IPR023633 ATPase, F1 complex, gamma subunit domain Reactome: R-HSA-163210 AUP74_RS04395 c2a09156343be52ded1d897f85205510 286 Gene3D G3DSA:3.40.1380.10 63 191 3.0E-41 T 11-11-2016 AUP74_RS04395 c2a09156343be52ded1d897f85205510 286 Pfam PF00231 ATP synthase 5 285 3.3E-90 T 11-11-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 AUP74_RS04395 c2a09156343be52ded1d897f85205510 286 PRINTS PR00126 ATP synthase gamma subunit signature 233 252 1.0E-35 T 11-11-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 AUP74_RS04395 c2a09156343be52ded1d897f85205510 286 PRINTS PR00126 ATP synthase gamma subunit signature 264 285 1.0E-35 T 11-11-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 AUP74_RS04395 c2a09156343be52ded1d897f85205510 286 PRINTS PR00126 ATP synthase gamma subunit signature 166 183 1.0E-35 T 11-11-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 AUP74_RS04395 c2a09156343be52ded1d897f85205510 286 PRINTS PR00126 ATP synthase gamma subunit signature 73 92 1.0E-35 T 11-11-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 AUP74_RS04395 c2a09156343be52ded1d897f85205510 286 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 286 2.5E-106 T 11-11-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 AUP74_RS04395 c2a09156343be52ded1d897f85205510 286 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 272 285 - T 11-11-2016 IPR023632 ATPase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210 AUP74_RS04395 c2a09156343be52ded1d897f85205510 286 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 286 35.768 T 11-11-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 AUP74_RS02430 d8c8c2f669a909dfc1c3c9d879f0ce11 334 SUPERFAMILY SSF144091 126 317 5.49E-33 T 11-11-2016 AUP74_RS02430 d8c8c2f669a909dfc1c3c9d879f0ce11 334 Pfam PF16733 Rhomboid N-terminal domain 4 64 1.4E-14 T 11-11-2016 IPR031976 Rhomboid protease, N-terminal AUP74_RS02430 d8c8c2f669a909dfc1c3c9d879f0ce11 334 Pfam PF01694 Rhomboid family 175 315 7.5E-26 T 11-11-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 AUP74_RS02430 d8c8c2f669a909dfc1c3c9d879f0ce11 334 Gene3D G3DSA:1.20.1540.10 171 314 8.7E-30 T 11-11-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 AUP74_RS12860 d9bc6de4dfa33e8ca6dae0792d3d5c65 457 Pfam PF08328 Adenylosuccinate lyase C-terminal 333 447 4.0E-50 T 11-11-2016 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234 AUP74_RS12860 d9bc6de4dfa33e8ca6dae0792d3d5c65 457 Gene3D G3DSA:1.20.200.10 122 391 7.2E-90 T 11-11-2016 AUP74_RS12860 d9bc6de4dfa33e8ca6dae0792d3d5c65 457 SUPERFAMILY SSF48557 5 449 3.61E-108 T 11-11-2016 IPR008948 L-Aspartase-like GO:0003824 AUP74_RS12860 d9bc6de4dfa33e8ca6dae0792d3d5c65 457 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 14 456 2.1E-138 T 11-11-2016 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AUP74_RS12860 d9bc6de4dfa33e8ca6dae0792d3d5c65 457 PRINTS PR00149 Fumarate lyase superfamily signature 253 280 3.9E-18 T 11-11-2016 IPR000362 Fumarate lyase family AUP74_RS12860 d9bc6de4dfa33e8ca6dae0792d3d5c65 457 PRINTS PR00149 Fumarate lyase superfamily signature 296 312 3.9E-18 T 11-11-2016 IPR000362 Fumarate lyase family AUP74_RS12860 d9bc6de4dfa33e8ca6dae0792d3d5c65 457 PRINTS PR00149 Fumarate lyase superfamily signature 119 137 3.9E-18 T 11-11-2016 IPR000362 Fumarate lyase family AUP74_RS12860 d9bc6de4dfa33e8ca6dae0792d3d5c65 457 PRINTS PR00149 Fumarate lyase superfamily signature 165 183 3.9E-18 T 11-11-2016 IPR000362 Fumarate lyase family AUP74_RS12860 d9bc6de4dfa33e8ca6dae0792d3d5c65 457 Gene3D G3DSA:1.10.275.10 4 121 1.8E-50 T 11-11-2016 IPR024083 Fumarase/histidase, N-terminal AUP74_RS12860 d9bc6de4dfa33e8ca6dae0792d3d5c65 457 ProSitePatterns PS00163 Fumarate lyases signature. 296 305 - T 11-11-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 AUP74_RS12860 d9bc6de4dfa33e8ca6dae0792d3d5c65 457 Pfam PF00206 Lyase 16 314 1.8E-71 T 11-11-2016 IPR022761 Fumarate lyase, N-terminal AUP74_RS12860 d9bc6de4dfa33e8ca6dae0792d3d5c65 457 Gene3D G3DSA:1.10.40.30 392 447 3.0E-32 T 11-11-2016 AUP74_RS08245 df3c4a1bcda69e92a9fa71b1c5154a1b 264 SUPERFAMILY SSF54637 114 262 1.63E-28 T 11-11-2016 IPR029069 HotDog domain AUP74_RS08245 df3c4a1bcda69e92a9fa71b1c5154a1b 264 Gene3D G3DSA:3.10.129.10 121 259 2.0E-9 T 11-11-2016 IPR029069 HotDog domain AUP74_RS08245 df3c4a1bcda69e92a9fa71b1c5154a1b 264 Pfam PF13622 Thioesterase-like superfamily 19 262 2.8E-48 T 11-11-2016 AUP74_RS08245 df3c4a1bcda69e92a9fa71b1c5154a1b 264 Gene3D G3DSA:3.10.129.10 18 106 1.2E-11 T 11-11-2016 IPR029069 HotDog domain AUP74_RS08245 df3c4a1bcda69e92a9fa71b1c5154a1b 264 SUPERFAMILY SSF54637 13 106 3.74E-17 T 11-11-2016 IPR029069 HotDog domain AUP74_RS13220 5ac8d953512109cdeb20a614337967f0 357 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 7 350 6.6E-155 T 11-11-2016 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 AUP74_RS13220 5ac8d953512109cdeb20a614337967f0 357 Gene3D G3DSA:3.20.20.70 11 351 2.0E-149 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS13220 5ac8d953512109cdeb20a614337967f0 357 SUPERFAMILY SSF51569 8 349 7.6E-135 T 11-11-2016 AUP74_RS13220 5ac8d953512109cdeb20a614337967f0 357 PIRSF PIRSF001361 1 355 1.8E-160 T 11-11-2016 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 AUP74_RS13220 5ac8d953512109cdeb20a614337967f0 357 Pfam PF00793 DAHP synthetase I family 45 340 8.6E-96 T 11-11-2016 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 AUP74_RS13590 8f3572c203b72cf0f809b8c2b6ff7f3e 658 SUPERFAMILY SSF82171 59 366 1.92E-36 T 11-11-2016 AUP74_RS13590 8f3572c203b72cf0f809b8c2b6ff7f3e 658 Gene3D G3DSA:2.120.10.30 55 299 8.7E-34 T 11-11-2016 IPR011042 Six-bladed beta-propeller, TolB-like AUP74_RS13590 8f3572c203b72cf0f809b8c2b6ff7f3e 658 Gene3D G3DSA:3.40.50.1820 307 640 2.1E-82 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS13590 8f3572c203b72cf0f809b8c2b6ff7f3e 658 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 106 365 1.4E-5 T 11-11-2016 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 AUP74_RS13590 8f3572c203b72cf0f809b8c2b6ff7f3e 658 Pfam PF00326 Prolyl oligopeptidase family 431 641 7.5E-45 T 11-11-2016 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 AUP74_RS13590 8f3572c203b72cf0f809b8c2b6ff7f3e 658 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 499 519 3.5E-6 T 11-11-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 AUP74_RS13590 8f3572c203b72cf0f809b8c2b6ff7f3e 658 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 557 572 3.5E-6 T 11-11-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 AUP74_RS13590 8f3572c203b72cf0f809b8c2b6ff7f3e 658 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 415 433 3.5E-6 T 11-11-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 AUP74_RS13590 8f3572c203b72cf0f809b8c2b6ff7f3e 658 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 441 465 3.5E-6 T 11-11-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 AUP74_RS13590 8f3572c203b72cf0f809b8c2b6ff7f3e 658 SUPERFAMILY SSF53474 385 641 6.46E-62 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 Gene3D G3DSA:1.20.120.160 953 1054 7.0E-8 T 11-11-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 Gene3D G3DSA:1.20.120.160 1266 1367 7.8E-23 T 11-11-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 SMART SM00448 1978 2091 3.3E-38 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 SUPERFAMILY SSF52172 1978 2096 4.84E-37 T 11-11-2016 IPR011006 CheY-like superfamily AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 SUPERFAMILY SSF50341 1807 1944 1.44E-23 T 11-11-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 SUPERFAMILY SSF47226 1266 1373 1.24E-21 T 11-11-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 SUPERFAMILY SSF47226 954 1072 1.71E-7 T 11-11-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 Pfam PF01584 CheW-like domain 1813 1946 9.1E-23 T 11-11-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 SUPERFAMILY SSF47226 428 535 5.1E-12 T 11-11-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 Pfam PF00072 Response regulator receiver domain 1980 2092 6.4E-26 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 SUPERFAMILY SSF55874 1624 1805 1.03E-34 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1712 1726 4.2E-10 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1768 1786 4.2E-10 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1792 1805 4.2E-10 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1671 1807 1.2E-16 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 SMART SM00260 1800 1944 2.2E-26 T 11-11-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 1486 1621 1.5E-5 T 11-11-2016 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 Gene3D G3DSA:1.10.287.560 1486 1540 2.0E-7 T 11-11-2016 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 SMART SM00073 808 909 0.0083 T 11-11-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 SMART SM00073 659 756 0.005 T 11-11-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 SMART SM00073 1267 1367 3.1E-7 T 11-11-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 Gene3D G3DSA:1.20.120.160 658 783 2.7E-27 T 11-11-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 Gene3D G3DSA:1.20.120.160 11 143 2.4E-12 T 11-11-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 Gene3D G3DSA:1.20.120.160 809 937 3.9E-21 T 11-11-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 Gene3D G3DSA:3.30.565.10 1623 1806 3.5E-32 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 Gene3D G3DSA:3.40.50.2300 1974 2096 2.6E-38 T 11-11-2016 AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 Pfam PF01627 Hpt domain 661 758 4.5E-11 T 11-11-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 Pfam PF01627 Hpt domain 1270 1360 2.2E-14 T 11-11-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 Pfam PF01627 Hpt domain 10 100 3.7E-7 T 11-11-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 Pfam PF01627 Hpt domain 813 914 3.4E-10 T 11-11-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 SUPERFAMILY SSF47226 658 775 2.88E-22 T 11-11-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 SMART SM01231 1485 1622 3.4E-11 T 11-11-2016 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 SUPERFAMILY SSF47226 9 131 4.06E-15 T 11-11-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 SMART SM00387 1667 1808 9.2E-22 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 Gene3D G3DSA:2.30.30.40 1899 1943 2.4E-20 T 11-11-2016 AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 Gene3D G3DSA:2.30.30.40 1808 1829 2.4E-20 T 11-11-2016 AUP74_RS05710 02c2815dad0163ba179f25eba54f5222 2101 SUPERFAMILY SSF47226 812 933 6.02E-18 T 11-11-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 AUP74_RS07045 5c23c23b417d76811cc51d16841ef794 377 PRINTS PR00474 Glutamate 5-kinase family signature 51 65 3.5E-53 T 11-11-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 AUP74_RS07045 5c23c23b417d76811cc51d16841ef794 377 PRINTS PR00474 Glutamate 5-kinase family signature 218 238 3.5E-53 T 11-11-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 AUP74_RS07045 5c23c23b417d76811cc51d16841ef794 377 PRINTS PR00474 Glutamate 5-kinase family signature 157 184 3.5E-53 T 11-11-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 AUP74_RS07045 5c23c23b417d76811cc51d16841ef794 377 PRINTS PR00474 Glutamate 5-kinase family signature 85 113 3.5E-53 T 11-11-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 AUP74_RS07045 5c23c23b417d76811cc51d16841ef794 377 PRINTS PR00474 Glutamate 5-kinase family signature 125 146 3.5E-53 T 11-11-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 AUP74_RS07045 5c23c23b417d76811cc51d16841ef794 377 SUPERFAMILY SSF53633 14 266 3.8E-67 T 11-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase AUP74_RS07045 5c23c23b417d76811cc51d16841ef794 377 Hamap MF_00456 Glutamate 5-kinase [proB]. 14 267 36.11 T 11-11-2016 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AUP74_RS07045 5c23c23b417d76811cc51d16841ef794 377 Gene3D G3DSA:2.30.130.10 283 374 4.9E-26 T 11-11-2016 IPR015947 PUA-like domain AUP74_RS07045 5c23c23b417d76811cc51d16841ef794 377 Pfam PF00696 Amino acid kinase family 15 243 3.6E-43 T 11-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase AUP74_RS07045 5c23c23b417d76811cc51d16841ef794 377 Pfam PF01472 PUA domain 286 356 2.1E-18 T 11-11-2016 IPR002478 PUA domain GO:0003723 AUP74_RS07045 5c23c23b417d76811cc51d16841ef794 377 TIGRFAM TIGR01027 proB: glutamate 5-kinase 15 375 5.2E-128 T 11-11-2016 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AUP74_RS07045 5c23c23b417d76811cc51d16841ef794 377 Gene3D G3DSA:3.40.1160.10 10 271 4.0E-57 T 11-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase AUP74_RS07045 5c23c23b417d76811cc51d16841ef794 377 SMART SM00359 286 369 3.0E-15 T 11-11-2016 IPR002478 PUA domain GO:0003723 AUP74_RS07045 5c23c23b417d76811cc51d16841ef794 377 PIRSF PIRSF000729 10 377 1.8E-125 T 11-11-2016 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 AUP74_RS07045 5c23c23b417d76811cc51d16841ef794 377 ProSitePatterns PS00902 Glutamate 5-kinase signature. 216 233 - T 11-11-2016 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AUP74_RS07045 5c23c23b417d76811cc51d16841ef794 377 SUPERFAMILY SSF88697 285 376 1.49E-22 T 11-11-2016 IPR015947 PUA-like domain AUP74_RS16695 d38a351dfd85aa8df928f69bf09d00f0 399 Gene3D G3DSA:3.60.70.12 4 270 5.7E-101 T 11-11-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AUP74_RS16695 d38a351dfd85aa8df928f69bf09d00f0 399 SUPERFAMILY SSF56266 9 396 5.1E-138 T 11-11-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AUP74_RS16695 d38a351dfd85aa8df928f69bf09d00f0 399 Pfam PF01960 ArgJ family 14 399 8.6E-145 T 11-11-2016 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AUP74_RS16695 d38a351dfd85aa8df928f69bf09d00f0 399 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 10 399 1.7E-123 T 11-11-2016 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AUP74_RS16695 d38a351dfd85aa8df928f69bf09d00f0 399 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 19 399 1.0E-118 T 11-11-2016 AUP74_RS16695 d38a351dfd85aa8df928f69bf09d00f0 399 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 399 146.923 T 11-11-2016 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AUP74_RS01150 5c84d1e386206f9e49a6c1207346a8b0 320 SUPERFAMILY SSF53474 129 316 1.57E-34 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS01150 5c84d1e386206f9e49a6c1207346a8b0 320 TIGRFAM TIGR01840 esterase_phb: esterase, PHB depolymerase family 44 253 1.4E-50 T 11-11-2016 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 AUP74_RS01150 5c84d1e386206f9e49a6c1207346a8b0 320 Pfam PF10503 Esterase PHB depolymerase 47 252 5.3E-27 T 11-11-2016 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 AUP74_RS01150 5c84d1e386206f9e49a6c1207346a8b0 320 Gene3D G3DSA:3.40.50.1820 28 303 1.1E-36 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS01150 5c84d1e386206f9e49a6c1207346a8b0 320 SUPERFAMILY SSF53474 30 129 2.3E-13 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS04195 65c4c51903a15c13ebe8a608cdc7a416 289 Gene3D G3DSA:3.40.50.300 42 284 1.9E-68 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04195 65c4c51903a15c13ebe8a608cdc7a416 289 Pfam PF00005 ABC transporter 58 213 5.2E-30 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AUP74_RS04195 65c4c51903a15c13ebe8a608cdc7a416 289 SUPERFAMILY SSF52540 42 276 1.25E-58 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04195 65c4c51903a15c13ebe8a608cdc7a416 289 SMART SM00382 66 260 3.3E-8 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS04195 65c4c51903a15c13ebe8a608cdc7a416 289 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 42 289 3.5E-121 T 11-11-2016 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 AUP74_RS04195 65c4c51903a15c13ebe8a608cdc7a416 289 ProSitePatterns PS00211 ABC transporters family signature. 186 200 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AUP74_RS06930 a3cff07c79ff15c6cd711305a87e9215 38 Pfam PF00444 Ribosomal protein L36 1 38 4.4E-21 T 11-11-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06930 a3cff07c79ff15c6cd711305a87e9215 38 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 37 - T 11-11-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06930 a3cff07c79ff15c6cd711305a87e9215 38 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 38 1.1E-21 T 11-11-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06930 a3cff07c79ff15c6cd711305a87e9215 38 SUPERFAMILY SSF57840 1 38 2.88E-17 T 11-11-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06930 a3cff07c79ff15c6cd711305a87e9215 38 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 38 18.586 T 11-11-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06930 a3cff07c79ff15c6cd711305a87e9215 38 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 38 9.0E-9 T 11-11-2016 AUP74_RS00180 77dec1abc296cb190be9c24d13914b65 294 Gene3D G3DSA:3.30.230.10 4 157 1.8E-53 T 11-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AUP74_RS00180 77dec1abc296cb190be9c24d13914b65 294 Pfam PF08544 GHMP kinases C terminal 206 262 1.1E-6 T 11-11-2016 IPR013750 GHMP kinase, C-terminal domain AUP74_RS00180 77dec1abc296cb190be9c24d13914b65 294 Gene3D G3DSA:3.30.70.890 161 285 4.2E-35 T 11-11-2016 IPR013750 GHMP kinase, C-terminal domain AUP74_RS00180 77dec1abc296cb190be9c24d13914b65 294 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 1 285 4.3E-86 T 11-11-2016 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 AUP74_RS00180 77dec1abc296cb190be9c24d13914b65 294 SUPERFAMILY SSF54211 3 156 6.75E-44 T 11-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold AUP74_RS00180 77dec1abc296cb190be9c24d13914b65 294 PIRSF PIRSF010376 1 288 9.6E-84 T 11-11-2016 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 AUP74_RS00180 77dec1abc296cb190be9c24d13914b65 294 Pfam PF00288 GHMP kinases N terminal domain 86 142 1.2E-7 T 11-11-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 AUP74_RS00180 77dec1abc296cb190be9c24d13914b65 294 Hamap MF_00061 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 3 273 32.475 T 11-11-2016 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 AUP74_RS00180 77dec1abc296cb190be9c24d13914b65 294 SUPERFAMILY SSF55060 160 283 6.71E-28 T 11-11-2016 IPR013750 GHMP kinase, C-terminal domain AUP74_RS08265 e0260a1068a555218ce83c452d9a6974 449 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 210 271 2.8E-22 T 11-11-2016 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 AUP74_RS08265 e0260a1068a555218ce83c452d9a6974 449 SUPERFAMILY SSF81891 181 416 2.22E-51 T 11-11-2016 AUP74_RS08265 e0260a1068a555218ce83c452d9a6974 449 Pfam PF12626 Polymerase A arginine-rich C-terminus 324 439 5.9E-43 T 11-11-2016 IPR025866 Polymerase A arginine-rich C-terminal domain AUP74_RS08265 e0260a1068a555218ce83c452d9a6974 449 Pfam PF01743 Poly A polymerase head domain 54 183 8.7E-35 T 11-11-2016 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 AUP74_RS08265 e0260a1068a555218ce83c452d9a6974 449 SUPERFAMILY SSF81301 27 180 2.72E-37 T 11-11-2016 AUP74_RS08265 e0260a1068a555218ce83c452d9a6974 449 Hamap MF_00957 Poly(A) polymerase I [pcnB]. 18 449 36.823 T 11-11-2016 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 AUP74_RS08265 e0260a1068a555218ce83c452d9a6974 449 Gene3D G3DSA:1.10.3090.10 183 415 2.8E-52 T 11-11-2016 AUP74_RS08265 e0260a1068a555218ce83c452d9a6974 449 TIGRFAM TIGR01942 pcnB: poly(A) polymerase 23 448 4.9E-164 T 11-11-2016 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 AUP74_RS08265 e0260a1068a555218ce83c452d9a6974 449 Gene3D G3DSA:3.30.460.10 35 182 5.8E-47 T 11-11-2016 AUP74_RS12230 ec891f0fe4d7f8ca31299fb8737f96e2 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 205 1.8E-17 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS12230 ec891f0fe4d7f8ca31299fb8737f96e2 217 SUPERFAMILY SSF52172 2 128 2.85E-35 T 11-11-2016 IPR011006 CheY-like superfamily AUP74_RS12230 ec891f0fe4d7f8ca31299fb8737f96e2 217 Gene3D G3DSA:1.10.10.10 119 213 3.2E-22 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS12230 ec891f0fe4d7f8ca31299fb8737f96e2 217 Gene3D G3DSA:3.40.50.2300 2 118 5.1E-37 T 11-11-2016 AUP74_RS12230 ec891f0fe4d7f8ca31299fb8737f96e2 217 Pfam PF00072 Response regulator receiver domain 4 115 7.6E-28 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS12230 ec891f0fe4d7f8ca31299fb8737f96e2 217 SMART SM00448 2 115 2.5E-30 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS12230 ec891f0fe4d7f8ca31299fb8737f96e2 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 1.1E-8 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS12230 ec891f0fe4d7f8ca31299fb8737f96e2 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 1.1E-8 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS12230 ec891f0fe4d7f8ca31299fb8737f96e2 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 1.1E-8 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS12230 ec891f0fe4d7f8ca31299fb8737f96e2 217 SMART SM00421 148 205 3.0E-16 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS12230 ec891f0fe4d7f8ca31299fb8737f96e2 217 SUPERFAMILY SSF46894 142 212 4.42E-18 T 11-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AUP74_RS12230 ec891f0fe4d7f8ca31299fb8737f96e2 217 ProSitePatterns PS00622 LuxR-type HTH domain signature. 165 192 - T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS11245 1a1eab839911dafa56b48311fe03b961 145 Hamap MF_00042 Ribonuclease H [rnhA]. 1 145 34.722 T 11-11-2016 IPR022892 Ribonuclease H GO:0004523 AUP74_RS11245 1a1eab839911dafa56b48311fe03b961 145 Pfam PF00075 RNase H 2 140 6.8E-52 T 11-11-2016 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 AUP74_RS11245 1a1eab839911dafa56b48311fe03b961 145 Gene3D G3DSA:3.30.420.10 2 142 7.7E-63 T 11-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 AUP74_RS11245 1a1eab839911dafa56b48311fe03b961 145 SUPERFAMILY SSF53098 2 141 1.26E-58 T 11-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 AUP74_RS09270 e22efecbd0f9c0ce5b3132fb911a13e3 959 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 4 685 5.7E-151 T 11-11-2016 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09270 e22efecbd0f9c0ce5b3132fb911a13e3 959 SUPERFAMILY SSF54292 1 74 2.08E-16 T 11-11-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AUP74_RS09270 e22efecbd0f9c0ce5b3132fb911a13e3 959 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 103 115 - T 11-11-2016 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09270 e22efecbd0f9c0ce5b3132fb911a13e3 959 SUPERFAMILY SSF50692 851 941 1.31E-8 T 11-11-2016 IPR009010 Aspartate decarboxylase-like domain AUP74_RS09270 e22efecbd0f9c0ce5b3132fb911a13e3 959 Gene3D G3DSA:2.40.40.20 862 942 1.3E-5 T 11-11-2016 AUP74_RS09270 e22efecbd0f9c0ce5b3132fb911a13e3 959 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 31 48 - T 11-11-2016 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09270 e22efecbd0f9c0ce5b3132fb911a13e3 959 SMART SM00929 88 128 2.3E-17 T 11-11-2016 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09270 e22efecbd0f9c0ce5b3132fb911a13e3 959 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 150 160 - T 11-11-2016 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09270 e22efecbd0f9c0ce5b3132fb911a13e3 959 SUPERFAMILY SSF54862 83 211 7.95E-30 T 11-11-2016 AUP74_RS09270 e22efecbd0f9c0ce5b3132fb911a13e3 959 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 4 74 6.0E-11 T 11-11-2016 AUP74_RS09270 e22efecbd0f9c0ce5b3132fb911a13e3 959 Gene3D G3DSA:3.30.70.20 198 228 4.3E-4 T 11-11-2016 AUP74_RS09270 e22efecbd0f9c0ce5b3132fb911a13e3 959 Gene3D G3DSA:3.30.70.20 147 157 4.3E-4 T 11-11-2016 AUP74_RS09270 e22efecbd0f9c0ce5b3132fb911a13e3 959 Gene3D G3DSA:3.40.50.740 534 696 4.3E-14 T 11-11-2016 AUP74_RS09270 e22efecbd0f9c0ce5b3132fb911a13e3 959 Gene3D G3DSA:3.40.50.740 331 362 4.3E-14 T 11-11-2016 AUP74_RS09270 e22efecbd0f9c0ce5b3132fb911a13e3 959 Gene3D G3DSA:3.10.20.30 7 51 1.8E-5 T 11-11-2016 IPR012675 Beta-grasp domain AUP74_RS09270 e22efecbd0f9c0ce5b3132fb911a13e3 959 Gene3D G3DSA:2.20.25.90 229 282 7.6E-10 T 11-11-2016 AUP74_RS09270 e22efecbd0f9c0ce5b3132fb911a13e3 959 SUPERFAMILY SSF53706 219 724 7.15E-48 T 11-11-2016 AUP74_RS09270 e22efecbd0f9c0ce5b3132fb911a13e3 959 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 88 125 1.4E-13 T 11-11-2016 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09270 e22efecbd0f9c0ce5b3132fb911a13e3 959 SMART SM00926 221 281 1.1E-5 T 11-11-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09270 e22efecbd0f9c0ce5b3132fb911a13e3 959 Pfam PF01568 Molydopterin dinucleotide binding domain 877 940 7.3E-6 T 11-11-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 AUP74_RS09495 3610e8cc80279397636a8d6639be85d4 243 Pfam PF13386 Cytochrome C biogenesis protein transmembrane region 9 209 1.1E-50 T 11-11-2016 AUP74_RS09760 e03d6c00d7890f2b0bbb44f2051f118d 170 Pfam PF01661 Macro domain 18 130 2.0E-42 T 11-11-2016 IPR002589 Macro domain AUP74_RS09760 e03d6c00d7890f2b0bbb44f2051f118d 170 Gene3D G3DSA:3.40.220.10 2 165 1.3E-64 T 11-11-2016 AUP74_RS09760 e03d6c00d7890f2b0bbb44f2051f118d 170 SUPERFAMILY SSF52949 2 163 5.89E-62 T 11-11-2016 AUP74_RS09760 e03d6c00d7890f2b0bbb44f2051f118d 170 SMART SM00506 1 130 2.0E-47 T 11-11-2016 IPR002589 Macro domain AUP74_RS01675 e78dee1292268308f83b557a46370027 215 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 42 215 2.1E-59 T 11-11-2016 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 AUP74_RS01675 e78dee1292268308f83b557a46370027 215 SUPERFAMILY SSF52540 21 215 5.08E-66 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS01675 e78dee1292268308f83b557a46370027 215 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 40 215 1.3E-62 T 11-11-2016 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 AUP74_RS01675 e78dee1292268308f83b557a46370027 215 PIRSF PIRSF015617 15 215 1.5E-63 T 11-11-2016 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 AUP74_RS01675 e78dee1292268308f83b557a46370027 215 Gene3D G3DSA:3.40.50.300 17 215 2.2E-72 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05545 0315e90ae3cfdbcfd37a2ecae006f6cf 109 PIRSF PIRSF000077 3 109 3.2E-43 T 11-11-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 AUP74_RS05545 0315e90ae3cfdbcfd37a2ecae006f6cf 109 SUPERFAMILY SSF52833 3 109 6.56E-40 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS05545 0315e90ae3cfdbcfd37a2ecae006f6cf 109 PRINTS PR00421 Thioredoxin family signature 25 33 6.5E-10 T 11-11-2016 AUP74_RS05545 0315e90ae3cfdbcfd37a2ecae006f6cf 109 PRINTS PR00421 Thioredoxin family signature 33 42 6.5E-10 T 11-11-2016 AUP74_RS05545 0315e90ae3cfdbcfd37a2ecae006f6cf 109 PRINTS PR00421 Thioredoxin family signature 73 84 6.5E-10 T 11-11-2016 AUP74_RS05545 0315e90ae3cfdbcfd37a2ecae006f6cf 109 ProSitePatterns PS00194 Thioredoxin family active site. 26 44 - T 11-11-2016 IPR017937 Thioredoxin, conserved site GO:0045454 AUP74_RS05545 0315e90ae3cfdbcfd37a2ecae006f6cf 109 Gene3D G3DSA:3.40.30.10 3 109 1.3E-39 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS05545 0315e90ae3cfdbcfd37a2ecae006f6cf 109 Pfam PF00085 Thioredoxin 6 107 7.5E-35 T 11-11-2016 IPR013766 Thioredoxin domain GO:0045454 AUP74_RS05545 0315e90ae3cfdbcfd37a2ecae006f6cf 109 TIGRFAM TIGR01068 thioredoxin: thioredoxin 10 108 8.2E-37 T 11-11-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 AUP74_RS09890 e9543363939e369ba3e50c5853f86695 250 Pfam PF01728 FtsJ-like methyltransferase 62 247 9.2E-21 T 11-11-2016 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 AUP74_RS09890 e9543363939e369ba3e50c5853f86695 250 SUPERFAMILY SSF55174 1 53 1.62E-6 T 11-11-2016 AUP74_RS09890 e9543363939e369ba3e50c5853f86695 250 PIRSF PIRSF005578 1 250 2.1E-90 T 11-11-2016 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 AUP74_RS09890 e9543363939e369ba3e50c5853f86695 250 SUPERFAMILY SSF53335 57 249 8.45E-28 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS09890 e9543363939e369ba3e50c5853f86695 250 Gene3D G3DSA:3.40.50.150 94 182 1.1E-8 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS09890 e9543363939e369ba3e50c5853f86695 250 Gene3D G3DSA:3.10.290.10 1 93 1.3E-16 T 11-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 AUP74_RS09890 e9543363939e369ba3e50c5853f86695 250 SMART SM00363 1 69 0.0057 T 11-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 AUP74_RS09890 e9543363939e369ba3e50c5853f86695 250 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 2 242 3.9E-56 T 11-11-2016 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 AUP74_RS09890 e9543363939e369ba3e50c5853f86695 250 Pfam PF01479 S4 domain 1 32 1.4E-7 T 11-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 AUP74_RS15665 42f98f16edd565ee6c07c4a894560a37 907 SUPERFAMILY SSF81593 210 319 6.2E-10 T 11-11-2016 AUP74_RS15665 42f98f16edd565ee6c07c4a894560a37 907 SUPERFAMILY SSF55021 824 902 4.58E-11 T 11-11-2016 AUP74_RS15665 42f98f16edd565ee6c07c4a894560a37 907 SUPERFAMILY SSF55021 715 787 4.23E-8 T 11-11-2016 AUP74_RS15665 42f98f16edd565ee6c07c4a894560a37 907 Gene3D G3DSA:3.30.460.10 87 175 2.1E-9 T 11-11-2016 AUP74_RS15665 42f98f16edd565ee6c07c4a894560a37 907 Gene3D G3DSA:3.30.70.260 825 898 5.5E-11 T 11-11-2016 AUP74_RS15665 42f98f16edd565ee6c07c4a894560a37 907 PIRSF PIRSF006288 22 905 0.0 T 11-11-2016 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 AUP74_RS15665 42f98f16edd565ee6c07c4a894560a37 907 Pfam PF08335 GlnD PII-uridylyltransferase 191 329 2.5E-36 T 11-11-2016 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 AUP74_RS15665 42f98f16edd565ee6c07c4a894560a37 907 Gene3D G3DSA:1.10.3210.10 437 626 1.1E-24 T 11-11-2016 IPR006674 HD domain AUP74_RS15665 42f98f16edd565ee6c07c4a894560a37 907 SMART SM00471 463 610 1.1E-9 T 11-11-2016 IPR003607 HD/PDEase domain AUP74_RS15665 42f98f16edd565ee6c07c4a894560a37 907 Pfam PF01966 HD domain 494 573 1.6E-9 T 11-11-2016 IPR006674 HD domain AUP74_RS15665 42f98f16edd565ee6c07c4a894560a37 907 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 48 897 8.5E-282 T 11-11-2016 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 AUP74_RS15665 42f98f16edd565ee6c07c4a894560a37 907 SUPERFAMILY SSF109604 434 568 2.79E-12 T 11-11-2016 AUP74_RS15665 42f98f16edd565ee6c07c4a894560a37 907 Pfam PF01909 Nucleotidyltransferase domain 81 114 3.2E-5 T 11-11-2016 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AUP74_RS15665 42f98f16edd565ee6c07c4a894560a37 907 SUPERFAMILY SSF81301 54 182 4.46E-23 T 11-11-2016 AUP74_RS15665 42f98f16edd565ee6c07c4a894560a37 907 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 907 307.992 T 11-11-2016 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 AUP74_RS01575 dbc6e663676920119a1e368e47c5357c 556 Gene3D G3DSA:3.40.50.1770 29 101 6.2E-4 T 11-11-2016 AUP74_RS01575 dbc6e663676920119a1e368e47c5357c 556 SUPERFAMILY SSF51905 492 555 1.74E-49 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS01575 dbc6e663676920119a1e368e47c5357c 556 SUPERFAMILY SSF51905 92 398 1.74E-49 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS01575 dbc6e663676920119a1e368e47c5357c 556 Pfam PF01593 Flavin containing amine oxidoreductase 101 553 2.7E-46 T 11-11-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 AUP74_RS01575 dbc6e663676920119a1e368e47c5357c 556 PRINTS PR00757 Flavin-containing amine oxidase signature 93 112 1.2E-6 T 11-11-2016 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 AUP74_RS01575 dbc6e663676920119a1e368e47c5357c 556 PRINTS PR00757 Flavin-containing amine oxidase signature 535 552 1.2E-6 T 11-11-2016 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 AUP74_RS01575 dbc6e663676920119a1e368e47c5357c 556 Gene3D G3DSA:3.90.660.10 386 414 4.8E-7 T 11-11-2016 AUP74_RS01575 dbc6e663676920119a1e368e47c5357c 556 Gene3D G3DSA:3.90.660.10 123 194 4.8E-7 T 11-11-2016 AUP74_RS01575 dbc6e663676920119a1e368e47c5357c 556 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 54 83 9.4E-4 T 11-11-2016 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal AUP74_RS01575 dbc6e663676920119a1e368e47c5357c 556 SUPERFAMILY SSF54373 387 503 1.77E-5 T 11-11-2016 AUP74_RS01575 dbc6e663676920119a1e368e47c5357c 556 Gene3D G3DSA:3.50.50.60 102 122 2.5E-34 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS01575 dbc6e663676920119a1e368e47c5357c 556 Gene3D G3DSA:3.50.50.60 492 554 2.5E-34 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS01575 dbc6e663676920119a1e368e47c5357c 556 Gene3D G3DSA:3.50.50.60 299 382 2.5E-34 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS00735 c570c5ee1fa78ffd131f0ccc3aa3f4f5 291 SMART SM01130 1 289 4.8E-149 T 11-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 AUP74_RS00735 c570c5ee1fa78ffd131f0ccc3aa3f4f5 291 Pfam PF00701 Dihydrodipicolinate synthetase family 2 286 4.7E-105 T 11-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 AUP74_RS00735 c570c5ee1fa78ffd131f0ccc3aa3f4f5 291 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 133 163 - T 11-11-2016 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AUP74_RS00735 c570c5ee1fa78ffd131f0ccc3aa3f4f5 291 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 38 55 - T 11-11-2016 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AUP74_RS00735 c570c5ee1fa78ffd131f0ccc3aa3f4f5 291 Gene3D G3DSA:3.20.20.70 1 291 1.5E-124 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS00735 c570c5ee1fa78ffd131f0ccc3aa3f4f5 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 103 119 7.2E-35 T 11-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 AUP74_RS00735 c570c5ee1fa78ffd131f0ccc3aa3f4f5 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 71 89 7.2E-35 T 11-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 AUP74_RS00735 c570c5ee1fa78ffd131f0ccc3aa3f4f5 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 35 56 7.2E-35 T 11-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 AUP74_RS00735 c570c5ee1fa78ffd131f0ccc3aa3f4f5 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 128 145 7.2E-35 T 11-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 AUP74_RS00735 c570c5ee1fa78ffd131f0ccc3aa3f4f5 291 SUPERFAMILY SSF51569 1 291 5.55E-108 T 11-11-2016 AUP74_RS00735 c570c5ee1fa78ffd131f0ccc3aa3f4f5 291 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 1 287 68.877 T 11-11-2016 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AUP74_RS00735 c570c5ee1fa78ffd131f0ccc3aa3f4f5 291 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 5 287 1.5E-115 T 11-11-2016 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AUP74_RS00735 c570c5ee1fa78ffd131f0ccc3aa3f4f5 291 PIRSF PIRSF001365 1 291 7.8E-100 T 11-11-2016 IPR002220 DapA-like GO:0008152|GO:0016829 AUP74_RS04220 76a068874eb5774fd8e0c250904d2592 453 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 10 442 3.4E-86 T 11-11-2016 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit AUP74_RS04220 76a068874eb5774fd8e0c250904d2592 453 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 20 448 9.8E-97 T 11-11-2016 IPR004681 TRAP transporter permease protein GO:0016021 AUP74_RS13785 0bfdea90ff90afd85e6313bc39284a38 745 Gene3D G3DSA:1.20.1050.40 59 191 1.1E-25 T 11-11-2016 IPR024080 Neurolysin/Thimet oligopeptidase, N-terminal AUP74_RS13785 0bfdea90ff90afd85e6313bc39284a38 745 Pfam PF01432 Peptidase family M3 276 724 4.9E-100 T 11-11-2016 IPR001567 Peptidase M3A/M3B GO:0004222|GO:0006508 AUP74_RS13785 0bfdea90ff90afd85e6313bc39284a38 745 Gene3D G3DSA:1.10.1370.10 194 399 3.1E-109 T 11-11-2016 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 AUP74_RS13785 0bfdea90ff90afd85e6313bc39284a38 745 Gene3D G3DSA:1.10.1370.10 553 733 3.1E-109 T 11-11-2016 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 AUP74_RS13785 0bfdea90ff90afd85e6313bc39284a38 745 SUPERFAMILY SSF55486 61 726 2.26E-169 T 11-11-2016 AUP74_RS13785 0bfdea90ff90afd85e6313bc39284a38 745 Gene3D G3DSA:3.40.390.10 409 552 6.6E-36 T 11-11-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 AUP74_RS02425 31ece2dff6cb97201e7403b7260cbf42 368 Pfam PF00571 CBS domain 266 316 3.4E-8 T 11-11-2016 IPR000644 CBS domain AUP74_RS02425 31ece2dff6cb97201e7403b7260cbf42 368 Pfam PF00571 CBS domain 195 253 4.4E-4 T 11-11-2016 IPR000644 CBS domain AUP74_RS02425 31ece2dff6cb97201e7403b7260cbf42 368 SUPERFAMILY SSF54631 188 318 7.43E-25 T 11-11-2016 AUP74_RS02425 31ece2dff6cb97201e7403b7260cbf42 368 Gene3D G3DSA:3.10.580.10 189 319 1.3E-16 T 11-11-2016 AUP74_RS02425 31ece2dff6cb97201e7403b7260cbf42 368 SMART SM00116 268 316 1.2 T 11-11-2016 IPR000644 CBS domain AUP74_RS02425 31ece2dff6cb97201e7403b7260cbf42 368 SMART SM00116 204 254 10.0 T 11-11-2016 IPR000644 CBS domain AUP74_RS02425 31ece2dff6cb97201e7403b7260cbf42 368 Pfam PF01595 Domain of unknown function DUF21 9 179 4.3E-29 T 11-11-2016 IPR002550 Domain of unknown function DUF21 AUP74_RS09770 48b81f0c8ee031bd94172d79ddd49874 161 ProSitePatterns PS00519 AsnC-type HTH domain signature. 26 52 - T 11-11-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site AUP74_RS09770 48b81f0c8ee031bd94172d79ddd49874 161 Gene3D G3DSA:3.30.70.920 61 157 1.3E-33 T 11-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AUP74_RS09770 48b81f0c8ee031bd94172d79ddd49874 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 24 35 2.3E-17 T 11-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 AUP74_RS09770 48b81f0c8ee031bd94172d79ddd49874 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 8 24 2.3E-17 T 11-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 AUP74_RS09770 48b81f0c8ee031bd94172d79ddd49874 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 35 54 2.3E-17 T 11-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 AUP74_RS09770 48b81f0c8ee031bd94172d79ddd49874 161 SUPERFAMILY SSF54909 70 156 1.61E-22 T 11-11-2016 IPR011008 Dimeric alpha-beta barrel AUP74_RS09770 48b81f0c8ee031bd94172d79ddd49874 161 SUPERFAMILY SSF46785 8 66 2.58E-18 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS09770 48b81f0c8ee031bd94172d79ddd49874 161 Gene3D G3DSA:1.10.10.10 11 60 5.0E-25 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS09770 48b81f0c8ee031bd94172d79ddd49874 161 Pfam PF13412 Winged helix-turn-helix DNA-binding 8 55 2.5E-17 T 11-11-2016 AUP74_RS09770 48b81f0c8ee031bd94172d79ddd49874 161 SMART SM00344 8 117 8.1E-47 T 11-11-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AUP74_RS09770 48b81f0c8ee031bd94172d79ddd49874 161 Pfam PF01037 Lrp/AsnC ligand binding domain 74 148 1.6E-24 T 11-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AUP74_RS13025 fbb49248fca659f51836b251a4835cf0 257 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 190 206 - T 11-11-2016 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 AUP74_RS13025 fbb49248fca659f51836b251a4835cf0 257 SUPERFAMILY SSF51556 1 254 2.14E-92 T 11-11-2016 IPR032466 Metal-dependent hydrolase AUP74_RS13025 fbb49248fca659f51836b251a4835cf0 257 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 1 253 1.4E-87 T 11-11-2016 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 AUP74_RS13025 fbb49248fca659f51836b251a4835cf0 257 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 1 9 - T 11-11-2016 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 AUP74_RS13025 fbb49248fca659f51836b251a4835cf0 257 Gene3D G3DSA:3.20.20.140 1 253 2.8E-88 T 11-11-2016 AUP74_RS13025 fbb49248fca659f51836b251a4835cf0 257 PIRSF PIRSF005902 1 257 6.2E-80 T 11-11-2016 IPR001130 TatD family GO:0016788 AUP74_RS13025 fbb49248fca659f51836b251a4835cf0 257 Pfam PF01026 TatD related DNase 2 253 3.5E-79 T 11-11-2016 IPR001130 TatD family GO:0016788 AUP74_RS09860 647bb6c81457aa815cc3a43ad936d25f 193 SUPERFAMILY SSF54719 84 192 7.07E-47 T 11-11-2016 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 AUP74_RS09860 647bb6c81457aa815cc3a43ad936d25f 193 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 82 2.8E-34 T 11-11-2016 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 AUP74_RS09860 647bb6c81457aa815cc3a43ad936d25f 193 PRINTS PR01703 Manganese superoxide dismutase signature 118 126 7.3E-23 T 11-11-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 AUP74_RS09860 647bb6c81457aa815cc3a43ad936d25f 193 PRINTS PR01703 Manganese superoxide dismutase signature 65 78 7.3E-23 T 11-11-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 AUP74_RS09860 647bb6c81457aa815cc3a43ad936d25f 193 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 7.3E-23 T 11-11-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 AUP74_RS09860 647bb6c81457aa815cc3a43ad936d25f 193 PRINTS PR01703 Manganese superoxide dismutase signature 156 168 7.3E-23 T 11-11-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 AUP74_RS09860 647bb6c81457aa815cc3a43ad936d25f 193 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 7.3E-23 T 11-11-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 AUP74_RS09860 647bb6c81457aa815cc3a43ad936d25f 193 Gene3D G3DSA:1.10.287.990 20 82 5.6E-24 T 11-11-2016 AUP74_RS09860 647bb6c81457aa815cc3a43ad936d25f 193 SUPERFAMILY SSF46609 1 84 4.58E-36 T 11-11-2016 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 AUP74_RS09860 647bb6c81457aa815cc3a43ad936d25f 193 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 89 191 1.9E-41 T 11-11-2016 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 AUP74_RS09860 647bb6c81457aa815cc3a43ad936d25f 193 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 158 165 - T 11-11-2016 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 AUP74_RS09860 647bb6c81457aa815cc3a43ad936d25f 193 PIRSF PIRSF000349 1 193 1.6E-89 T 11-11-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 AUP74_RS15530 6d53287a6f6a0b292e36b0ce4df42bce 465 Gene3D G3DSA:3.40.50.1100 202 434 4.3E-91 T 11-11-2016 AUP74_RS15530 6d53287a6f6a0b292e36b0ce4df42bce 465 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 99 407 1.4E-22 T 11-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme AUP74_RS15530 6d53287a6f6a0b292e36b0ce4df42bce 465 Gene3D G3DSA:3.40.50.1100 129 201 3.1E-6 T 11-11-2016 AUP74_RS15530 6d53287a6f6a0b292e36b0ce4df42bce 465 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 102 116 - T 11-11-2016 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 AUP74_RS15530 6d53287a6f6a0b292e36b0ce4df42bce 465 TIGRFAM TIGR00260 thrC: threonine synthase 69 423 1.1E-81 T 11-11-2016 IPR004450 Threonine synthase-like AUP74_RS15530 6d53287a6f6a0b292e36b0ce4df42bce 465 Gene3D G3DSA:3.90.1380.10 2 85 5.6E-29 T 11-11-2016 IPR029144 Threonine synthase, N-terminal AUP74_RS15530 6d53287a6f6a0b292e36b0ce4df42bce 465 Pfam PF14821 Threonine synthase N terminus 2 80 9.6E-28 T 11-11-2016 IPR029144 Threonine synthase, N-terminal AUP74_RS15530 6d53287a6f6a0b292e36b0ce4df42bce 465 SUPERFAMILY SSF53686 2 460 3.03E-157 T 11-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme AUP74_RS03920 5d685795ab6a59d9c9ced033db12283f 238 Pfam PF02390 Putative methyltransferase 64 233 1.8E-58 T 11-11-2016 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 AUP74_RS03920 5d685795ab6a59d9c9ced033db12283f 238 SUPERFAMILY SSF53335 14 237 1.43E-43 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS03920 5d685795ab6a59d9c9ced033db12283f 238 Gene3D G3DSA:3.40.50.150 62 205 6.3E-18 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS03920 5d685795ab6a59d9c9ced033db12283f 238 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 59 234 2.8E-60 T 11-11-2016 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 AUP74_RS03920 5d685795ab6a59d9c9ced033db12283f 238 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 24 238 31.119 T 11-11-2016 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 AUP74_RS13175 0b2f8f406476ff97409a0f267782088b 112 Pfam PF04358 DsrC like protein 7 112 2.8E-39 T 11-11-2016 IPR007453 Sulphur transfer protein DsrC/TusE AUP74_RS13175 0b2f8f406476ff97409a0f267782088b 112 Gene3D G3DSA:1.10.10.370 43 112 5.4E-30 T 11-11-2016 AUP74_RS13175 0b2f8f406476ff97409a0f267782088b 112 PIRSF PIRSF006223 5 112 5.5E-37 T 11-11-2016 IPR007453 Sulphur transfer protein DsrC/TusE AUP74_RS13175 0b2f8f406476ff97409a0f267782088b 112 Gene3D G3DSA:3.30.1420.10 4 42 1.4E-15 T 11-11-2016 AUP74_RS13175 0b2f8f406476ff97409a0f267782088b 112 TIGRFAM TIGR03342 dsrC_tusE_dsvC: sulfur relay protein, TusE/DsrC/DsvC family 6 112 1.2E-44 T 11-11-2016 IPR007453 Sulphur transfer protein DsrC/TusE AUP74_RS13175 0b2f8f406476ff97409a0f267782088b 112 SUPERFAMILY SSF69721 5 112 1.12E-36 T 11-11-2016 IPR025526 DsrC-like domain AUP74_RS03225 11c84fa4aabb0019c37ef0c452712a2f 257 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 3 256 4.1E-116 T 11-11-2016 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 AUP74_RS03225 11c84fa4aabb0019c37ef0c452712a2f 257 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 2 256 49.349 T 11-11-2016 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 AUP74_RS03225 11c84fa4aabb0019c37ef0c452712a2f 257 Gene3D G3DSA:3.20.20.70 5 256 8.4E-111 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS03225 11c84fa4aabb0019c37ef0c452712a2f 257 Pfam PF00977 Histidine biosynthesis protein 6 239 3.3E-92 T 11-11-2016 IPR006062 Histidine biosynthesis GO:0000105 AUP74_RS03225 11c84fa4aabb0019c37ef0c452712a2f 257 SUPERFAMILY SSF51366 3 256 7.85E-87 T 11-11-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 AUP74_RS13545 639f786884f0a20d3f7a0f3eb3d36bf5 170 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 30 61 - T 11-11-2016 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 AUP74_RS13545 639f786884f0a20d3f7a0f3eb3d36bf5 170 Hamap MF_00105 Transcription elongation factor GreA [greA]. 15 167 25.802 T 11-11-2016 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 AUP74_RS13545 639f786884f0a20d3f7a0f3eb3d36bf5 170 Gene3D G3DSA:3.10.50.30 89 168 4.7E-27 T 11-11-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 AUP74_RS13545 639f786884f0a20d3f7a0f3eb3d36bf5 170 PIRSF PIRSF006092 14 170 2.5E-45 T 11-11-2016 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 AUP74_RS13545 639f786884f0a20d3f7a0f3eb3d36bf5 170 SUPERFAMILY SSF54534 94 168 5.49E-20 T 11-11-2016 AUP74_RS13545 639f786884f0a20d3f7a0f3eb3d36bf5 170 Hamap MF_00930 Transcription elongation factor GreB [greB]. 14 169 49.818 T 11-11-2016 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 AUP74_RS13545 639f786884f0a20d3f7a0f3eb3d36bf5 170 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 96 168 5.4E-23 T 11-11-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 AUP74_RS13545 639f786884f0a20d3f7a0f3eb3d36bf5 170 Pfam PF03449 Transcription elongation factor, N-terminal 18 87 7.0E-24 T 11-11-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 AUP74_RS13545 639f786884f0a20d3f7a0f3eb3d36bf5 170 TIGRFAM TIGR01461 greB: transcription elongation factor GreB 17 168 3.0E-64 T 11-11-2016 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 AUP74_RS13545 639f786884f0a20d3f7a0f3eb3d36bf5 170 SUPERFAMILY SSF46557 17 90 6.54E-25 T 11-11-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 AUP74_RS13545 639f786884f0a20d3f7a0f3eb3d36bf5 170 Gene3D G3DSA:1.10.287.180 18 88 2.5E-23 T 11-11-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 AUP74_RS12920 1c3af442e2dccb50de2c51590aaf31aa 740 SUPERFAMILY SSF47203 303 448 3.06E-25 T 11-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AUP74_RS12920 1c3af442e2dccb50de2c51590aaf31aa 740 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 303 446 1.7E-15 T 11-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AUP74_RS12920 1c3af442e2dccb50de2c51590aaf31aa 740 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 180 271 3.4E-9 T 11-11-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 AUP74_RS12920 1c3af442e2dccb50de2c51590aaf31aa 740 SUPERFAMILY SSF56645 62 298 4.71E-47 T 11-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 AUP74_RS12920 1c3af442e2dccb50de2c51590aaf31aa 740 Gene3D G3DSA:1.20.140.10 293 449 7.0E-27 T 11-11-2016 AUP74_RS12920 1c3af442e2dccb50de2c51590aaf31aa 740 Gene3D G3DSA:1.10.540.10 39 177 1.8E-31 T 11-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 AUP74_RS12920 1c3af442e2dccb50de2c51590aaf31aa 740 Gene3D G3DSA:2.40.110.10 180 292 8.3E-18 T 11-11-2016 AUP74_RS12920 1c3af442e2dccb50de2c51590aaf31aa 740 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 81 175 9.4E-18 T 11-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 AUP74_RS12920 1c3af442e2dccb50de2c51590aaf31aa 740 Pfam PF09317 Domain of unknown function (DUF1974) 457 735 1.4E-93 T 11-11-2016 IPR015396 Acyl-CoA dehydrogenase, C-termina, bacterial type GO:0003995|GO:0033539|GO:0055114 AUP74_RS12275 50b9e1e5a99455f93474c163bcf6e41e 228 Gene3D G3DSA:1.10.357.10 12 194 2.1E-28 T 11-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 AUP74_RS12275 50b9e1e5a99455f93474c163bcf6e41e 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 2.3E-9 T 11-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AUP74_RS12275 50b9e1e5a99455f93474c163bcf6e41e 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 2.3E-9 T 11-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AUP74_RS12275 50b9e1e5a99455f93474c163bcf6e41e 228 SUPERFAMILY SSF48498 118 197 4.89E-5 T 11-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AUP74_RS12275 50b9e1e5a99455f93474c163bcf6e41e 228 SUPERFAMILY SSF46689 10 81 8.98E-17 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS12275 50b9e1e5a99455f93474c163bcf6e41e 228 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 61 2.6E-14 T 11-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AUP74_RS10440 102df1a39bc3e69505a3722618c2c9f0 102 Gene3D G3DSA:3.30.300.90 1 99 3.1E-29 T 11-11-2016 IPR002634 BolA protein AUP74_RS10440 102df1a39bc3e69505a3722618c2c9f0 102 Pfam PF01722 BolA-like protein 12 84 1.2E-26 T 11-11-2016 IPR002634 BolA protein AUP74_RS10440 102df1a39bc3e69505a3722618c2c9f0 102 PIRSF PIRSF003113 1 97 1.8E-31 T 11-11-2016 IPR002634 BolA protein AUP74_RS10440 102df1a39bc3e69505a3722618c2c9f0 102 SUPERFAMILY SSF82657 2 88 4.45E-27 T 11-11-2016 IPR002634 BolA protein AUP74_RS01650 c043fd6e460b8f4973f96e42734d1b9a 905 Pfam PF00593 TonB dependent receptor 585 904 2.9E-23 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS01650 c043fd6e460b8f4973f96e42734d1b9a 905 Gene3D G3DSA:2.170.130.10 41 182 8.7E-29 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS01650 c043fd6e460b8f4973f96e42734d1b9a 905 SUPERFAMILY SSF56935 725 905 7.33E-79 T 11-11-2016 AUP74_RS01650 c043fd6e460b8f4973f96e42734d1b9a 905 SUPERFAMILY SSF56935 475 689 7.33E-79 T 11-11-2016 AUP74_RS01650 c043fd6e460b8f4973f96e42734d1b9a 905 SUPERFAMILY SSF56935 310 443 7.33E-79 T 11-11-2016 AUP74_RS01650 c043fd6e460b8f4973f96e42734d1b9a 905 SUPERFAMILY SSF56935 46 244 7.33E-79 T 11-11-2016 AUP74_RS01650 c043fd6e460b8f4973f96e42734d1b9a 905 Gene3D G3DSA:2.40.170.20 287 905 5.9E-66 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS01650 c043fd6e460b8f4973f96e42734d1b9a 905 Gene3D G3DSA:2.40.170.20 183 242 5.9E-66 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS01650 c043fd6e460b8f4973f96e42734d1b9a 905 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 888 905 - T 11-11-2016 IPR010917 TonB-dependent receptor, conserved site AUP74_RS01650 c043fd6e460b8f4973f96e42734d1b9a 905 Pfam PF07715 TonB-dependent Receptor Plug Domain 63 179 3.1E-17 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS03625 c98fefe68473fbc8e19b06abe9920512 360 Gene3D G3DSA:3.30.70.270 202 358 1.2E-48 T 11-11-2016 AUP74_RS03625 c98fefe68473fbc8e19b06abe9920512 360 Pfam PF00990 Diguanylate cyclase, GGDEF domain 200 356 1.1E-44 T 11-11-2016 IPR000160 GGDEF domain AUP74_RS03625 c98fefe68473fbc8e19b06abe9920512 360 SMART SM00267 189 360 5.1E-53 T 11-11-2016 IPR000160 GGDEF domain AUP74_RS03625 c98fefe68473fbc8e19b06abe9920512 360 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 196 358 5.1E-48 T 11-11-2016 IPR000160 GGDEF domain AUP74_RS03625 c98fefe68473fbc8e19b06abe9920512 360 SUPERFAMILY SSF55073 205 358 1.18E-44 T 11-11-2016 IPR029787 Nucleotide cyclase AUP74_RS08205 d8cbc15e99d768631ef95f15beb654f1 313 Gene3D G3DSA:2.30.130.10 249 311 8.8E-21 T 11-11-2016 IPR015947 PUA-like domain AUP74_RS08205 d8cbc15e99d768631ef95f15beb654f1 313 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 33 184 6.7E-56 T 11-11-2016 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 AUP74_RS08205 d8cbc15e99d768631ef95f15beb654f1 313 Pfam PF09157 Pseudouridine synthase II TruB, C-terminal 250 310 3.7E-17 T 11-11-2016 IPR015240 tRNA pseudouridine synthase II, TruB, subfamily 1, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS08205 d8cbc15e99d768631ef95f15beb654f1 313 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 185 244 8.4E-18 T 11-11-2016 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 AUP74_RS08205 d8cbc15e99d768631ef95f15beb654f1 313 SUPERFAMILY SSF55120 10 242 2.42E-76 T 11-11-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS08205 d8cbc15e99d768631ef95f15beb654f1 313 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 11 310 18.887 T 11-11-2016 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS08205 d8cbc15e99d768631ef95f15beb654f1 313 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 11 223 1.9E-75 T 11-11-2016 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS08205 d8cbc15e99d768631ef95f15beb654f1 313 SUPERFAMILY SSF88697 249 311 1.49E-10 T 11-11-2016 IPR015947 PUA-like domain AUP74_RS10985 93f69186eaa4a48d0243bc28de91f2f1 464 Pfam PF10415 Fumarase C C-terminus 403 454 1.5E-17 T 11-11-2016 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AUP74_RS10985 93f69186eaa4a48d0243bc28de91f2f1 464 Gene3D G3DSA:1.10.40.30 414 457 8.8E-18 T 11-11-2016 AUP74_RS10985 93f69186eaa4a48d0243bc28de91f2f1 464 Hamap MF_00743 Fumarate hydratase class II [fumC]. 5 457 74.639 T 11-11-2016 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AUP74_RS10985 93f69186eaa4a48d0243bc28de91f2f1 464 Gene3D G3DSA:1.20.200.10 134 413 3.8E-86 T 11-11-2016 AUP74_RS10985 93f69186eaa4a48d0243bc28de91f2f1 464 Gene3D G3DSA:1.10.275.10 4 133 4.6E-50 T 11-11-2016 IPR024083 Fumarase/histidase, N-terminal AUP74_RS10985 93f69186eaa4a48d0243bc28de91f2f1 464 Pfam PF00206 Lyase 13 337 5.8E-97 T 11-11-2016 IPR022761 Fumarate lyase, N-terminal AUP74_RS10985 93f69186eaa4a48d0243bc28de91f2f1 464 SUPERFAMILY SSF48557 5 453 1.91E-136 T 11-11-2016 IPR008948 L-Aspartase-like GO:0003824 AUP74_RS10985 93f69186eaa4a48d0243bc28de91f2f1 464 ProSitePatterns PS00163 Fumarate lyases signature. 312 321 - T 11-11-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 AUP74_RS10985 93f69186eaa4a48d0243bc28de91f2f1 464 PRINTS PR00149 Fumarate lyase superfamily signature 175 193 2.7E-31 T 11-11-2016 IPR000362 Fumarate lyase family AUP74_RS10985 93f69186eaa4a48d0243bc28de91f2f1 464 PRINTS PR00149 Fumarate lyase superfamily signature 266 293 2.7E-31 T 11-11-2016 IPR000362 Fumarate lyase family AUP74_RS10985 93f69186eaa4a48d0243bc28de91f2f1 464 PRINTS PR00149 Fumarate lyase superfamily signature 129 147 2.7E-31 T 11-11-2016 IPR000362 Fumarate lyase family AUP74_RS10985 93f69186eaa4a48d0243bc28de91f2f1 464 PRINTS PR00149 Fumarate lyase superfamily signature 312 328 2.7E-31 T 11-11-2016 IPR000362 Fumarate lyase family AUP74_RS04880 d1225cdcb5ae84ae09595202c4fd9ab0 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 2.1E-17 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS04880 d1225cdcb5ae84ae09595202c4fd9ab0 293 Gene3D G3DSA:3.40.190.10 88 175 2.3E-16 T 11-11-2016 AUP74_RS04880 d1225cdcb5ae84ae09595202c4fd9ab0 293 SUPERFAMILY SSF53850 91 292 6.62E-45 T 11-11-2016 AUP74_RS04880 d1225cdcb5ae84ae09595202c4fd9ab0 293 Gene3D G3DSA:1.10.10.10 4 87 2.9E-22 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS04880 d1225cdcb5ae84ae09595202c4fd9ab0 293 SUPERFAMILY SSF46785 1 111 1.69E-20 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS04880 d1225cdcb5ae84ae09595202c4fd9ab0 293 Pfam PF03466 LysR substrate binding domain 89 291 5.6E-50 T 11-11-2016 IPR005119 LysR, substrate-binding AUP74_RS04880 d1225cdcb5ae84ae09595202c4fd9ab0 293 Gene3D G3DSA:3.40.190.10 176 259 1.9E-21 T 11-11-2016 AUP74_RS06925 c4c189634f63a6dc539eec0fc3ddff27 448 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 23 433 2.1E-130 T 11-11-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AUP74_RS06925 c4c189634f63a6dc539eec0fc3ddff27 448 Hamap MF_01465 Protein translocase subunit SecY [secY]. 11 437 29.311 T 11-11-2016 IPR026593 Protein translocase subunit SecY AUP74_RS06925 c4c189634f63a6dc539eec0fc3ddff27 448 Gene3D G3DSA:1.10.3370.10 10 441 2.3E-158 T 11-11-2016 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AUP74_RS06925 c4c189634f63a6dc539eec0fc3ddff27 448 SUPERFAMILY SSF103491 10 428 2.22E-128 T 11-11-2016 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AUP74_RS06925 c4c189634f63a6dc539eec0fc3ddff27 448 PIRSF PIRSF004557 6 444 4.9E-124 T 11-11-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AUP74_RS06925 c4c189634f63a6dc539eec0fc3ddff27 448 PRINTS PR00303 Preprotein translocase SecY subunit signature 273 292 3.3E-95 T 11-11-2016 AUP74_RS06925 c4c189634f63a6dc539eec0fc3ddff27 448 PRINTS PR00303 Preprotein translocase SecY subunit signature 76 96 3.3E-95 T 11-11-2016 AUP74_RS06925 c4c189634f63a6dc539eec0fc3ddff27 448 PRINTS PR00303 Preprotein translocase SecY subunit signature 117 140 3.3E-95 T 11-11-2016 AUP74_RS06925 c4c189634f63a6dc539eec0fc3ddff27 448 PRINTS PR00303 Preprotein translocase SecY subunit signature 179 202 3.3E-95 T 11-11-2016 AUP74_RS06925 c4c189634f63a6dc539eec0fc3ddff27 448 PRINTS PR00303 Preprotein translocase SecY subunit signature 153 178 3.3E-95 T 11-11-2016 AUP74_RS06925 c4c189634f63a6dc539eec0fc3ddff27 448 PRINTS PR00303 Preprotein translocase SecY subunit signature 319 341 3.3E-95 T 11-11-2016 AUP74_RS06925 c4c189634f63a6dc539eec0fc3ddff27 448 PRINTS PR00303 Preprotein translocase SecY subunit signature 406 424 3.3E-95 T 11-11-2016 AUP74_RS06925 c4c189634f63a6dc539eec0fc3ddff27 448 PRINTS PR00303 Preprotein translocase SecY subunit signature 374 392 3.3E-95 T 11-11-2016 AUP74_RS06925 c4c189634f63a6dc539eec0fc3ddff27 448 PRINTS PR00303 Preprotein translocase SecY subunit signature 24 42 3.3E-95 T 11-11-2016 AUP74_RS06925 c4c189634f63a6dc539eec0fc3ddff27 448 Pfam PF00344 SecY translocase 77 421 4.3E-115 T 11-11-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AUP74_RS06925 c4c189634f63a6dc539eec0fc3ddff27 448 ProSitePatterns PS00755 Protein secY signature 1. 77 96 - T 11-11-2016 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AUP74_RS03490 6edc8e81749827c05ad01fb2ab127364 305 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 31 49 - T 11-11-2016 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 AUP74_RS03490 6edc8e81749827c05ad01fb2ab127364 305 TIGRFAM TIGR01136 cysKM: cysteine synthase 7 300 5.4E-119 T 11-11-2016 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 AUP74_RS03490 6edc8e81749827c05ad01fb2ab127364 305 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 288 3.3E-64 T 11-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme AUP74_RS03490 6edc8e81749827c05ad01fb2ab127364 305 Gene3D G3DSA:3.40.50.1100 1 40 2.8E-62 T 11-11-2016 AUP74_RS03490 6edc8e81749827c05ad01fb2ab127364 305 Gene3D G3DSA:3.40.50.1100 148 299 2.8E-62 T 11-11-2016 AUP74_RS03490 6edc8e81749827c05ad01fb2ab127364 305 Gene3D G3DSA:3.40.50.1100 41 142 1.8E-41 T 11-11-2016 AUP74_RS03490 6edc8e81749827c05ad01fb2ab127364 305 SUPERFAMILY SSF53686 3 299 9.95E-92 T 11-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme AUP74_RS03490 6edc8e81749827c05ad01fb2ab127364 305 TIGRFAM TIGR01139 cysK: cysteine synthase A 7 300 1.5E-123 T 11-11-2016 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 AUP74_RS12655 06ae4c675b66c4473be5701bab273f2d 913 SUPERFAMILY SSF81660 337 540 3.6E-30 T 11-11-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 AUP74_RS12655 06ae4c675b66c4473be5701bab273f2d 913 SUPERFAMILY SSF81653 121 226 1.57E-30 T 11-11-2016 AUP74_RS12655 06ae4c675b66c4473be5701bab273f2d 913 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 167 181 1.4E-36 T 11-11-2016 AUP74_RS12655 06ae4c675b66c4473be5701bab273f2d 913 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 558 568 1.4E-36 T 11-11-2016 AUP74_RS12655 06ae4c675b66c4473be5701bab273f2d 913 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 641 660 1.4E-36 T 11-11-2016 AUP74_RS12655 06ae4c675b66c4473be5701bab273f2d 913 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 536 547 1.4E-36 T 11-11-2016 AUP74_RS12655 06ae4c675b66c4473be5701bab273f2d 913 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 665 677 1.4E-36 T 11-11-2016 AUP74_RS12655 06ae4c675b66c4473be5701bab273f2d 913 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 330 344 1.4E-36 T 11-11-2016 AUP74_RS12655 06ae4c675b66c4473be5701bab273f2d 913 Gene3D G3DSA:2.70.150.10 27 60 6.4E-38 T 11-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 AUP74_RS12655 06ae4c675b66c4473be5701bab273f2d 913 Gene3D G3DSA:2.70.150.10 115 227 6.4E-38 T 11-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 AUP74_RS12655 06ae4c675b66c4473be5701bab273f2d 913 SMART SM00831 9 82 4.0E-29 T 11-11-2016 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 AUP74_RS12655 06ae4c675b66c4473be5701bab273f2d 913 SUPERFAMILY SSF56784 328 348 8.24E-53 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS12655 06ae4c675b66c4473be5701bab273f2d 913 SUPERFAMILY SSF56784 489 743 8.24E-53 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS12655 06ae4c675b66c4473be5701bab273f2d 913 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 613 731 2.8E-33 T 11-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AUP74_RS12655 06ae4c675b66c4473be5701bab273f2d 913 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 89 355 1.5E-39 T 11-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AUP74_RS12655 06ae4c675b66c4473be5701bab273f2d 913 Gene3D G3DSA:1.20.1110.10 610 895 6.1E-101 T 11-11-2016 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 AUP74_RS12655 06ae4c675b66c4473be5701bab273f2d 913 Gene3D G3DSA:1.20.1110.10 61 114 6.1E-101 T 11-11-2016 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 AUP74_RS12655 06ae4c675b66c4473be5701bab273f2d 913 SUPERFAMILY SSF81665 8 120 5.49E-114 T 11-11-2016 AUP74_RS12655 06ae4c675b66c4473be5701bab273f2d 913 SUPERFAMILY SSF81665 691 894 5.49E-114 T 11-11-2016 AUP74_RS12655 06ae4c675b66c4473be5701bab273f2d 913 SUPERFAMILY SSF81665 231 324 5.49E-114 T 11-11-2016 AUP74_RS12655 06ae4c675b66c4473be5701bab273f2d 913 Pfam PF00122 E1-E2 ATPase 88 321 1.4E-64 T 11-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 AUP74_RS12655 06ae4c675b66c4473be5701bab273f2d 913 Pfam PF00702 haloacid dehalogenase-like hydrolase 328 654 6.4E-20 T 11-11-2016 AUP74_RS12655 06ae4c675b66c4473be5701bab273f2d 913 Pfam PF00690 Cation transporter/ATPase, N-terminus 10 77 1.1E-17 T 11-11-2016 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 AUP74_RS12655 06ae4c675b66c4473be5701bab273f2d 913 Gene3D G3DSA:3.40.1110.10 321 543 9.4E-37 T 11-11-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 AUP74_RS12655 06ae4c675b66c4473be5701bab273f2d 913 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 673 698 2.4E-16 T 11-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AUP74_RS12655 06ae4c675b66c4473be5701bab273f2d 913 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 492 510 2.4E-16 T 11-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AUP74_RS12655 06ae4c675b66c4473be5701bab273f2d 913 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 613 629 2.4E-16 T 11-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AUP74_RS12655 06ae4c675b66c4473be5701bab273f2d 913 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 641 657 2.4E-16 T 11-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AUP74_RS12655 06ae4c675b66c4473be5701bab273f2d 913 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 332 338 - T 11-11-2016 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 AUP74_RS12655 06ae4c675b66c4473be5701bab273f2d 913 Pfam PF00689 Cation transporting ATPase, C-terminus 725 894 2.9E-40 T 11-11-2016 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 AUP74_RS00375 4d09c7e46af75d148315db26a01c8283 269 Pfam PF00571 CBS domain 127 167 1.2E-5 T 11-11-2016 IPR000644 CBS domain AUP74_RS00375 4d09c7e46af75d148315db26a01c8283 269 Pfam PF00571 CBS domain 47 104 7.0E-4 T 11-11-2016 IPR000644 CBS domain AUP74_RS00375 4d09c7e46af75d148315db26a01c8283 269 SUPERFAMILY SSF56176 182 267 2.13E-22 T 11-11-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 AUP74_RS00375 4d09c7e46af75d148315db26a01c8283 269 SMART SM01091 184 262 2.7E-28 T 11-11-2016 IPR005170 Transporter-associated domain AUP74_RS00375 4d09c7e46af75d148315db26a01c8283 269 SMART SM00116 56 105 0.19 T 11-11-2016 IPR000644 CBS domain AUP74_RS00375 4d09c7e46af75d148315db26a01c8283 269 SMART SM00116 119 167 1.5 T 11-11-2016 IPR000644 CBS domain AUP74_RS00375 4d09c7e46af75d148315db26a01c8283 269 Gene3D G3DSA:3.10.580.10 36 175 1.9E-19 T 11-11-2016 AUP74_RS00375 4d09c7e46af75d148315db26a01c8283 269 Gene3D G3DSA:3.30.465.10 176 261 9.8E-28 T 11-11-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 AUP74_RS00375 4d09c7e46af75d148315db26a01c8283 269 SUPERFAMILY SSF54631 35 170 4.42E-32 T 11-11-2016 AUP74_RS00375 4d09c7e46af75d148315db26a01c8283 269 Pfam PF03471 Transporter associated domain 185 261 6.2E-21 T 11-11-2016 IPR005170 Transporter-associated domain AUP74_RS10210 21f5b45559a59f908ff04df5fbd68a07 174 Pfam PF02627 Carboxymuconolactone decarboxylase family 47 121 1.4E-6 T 11-11-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AUP74_RS10210 21f5b45559a59f908ff04df5fbd68a07 174 SUPERFAMILY SSF69118 9 174 3.88E-37 T 11-11-2016 IPR029032 AhpD-like Reactome: R-HSA-5628897 AUP74_RS10210 21f5b45559a59f908ff04df5fbd68a07 174 Gene3D G3DSA:1.20.5.810 15 54 1.8E-8 T 11-11-2016 AUP74_RS10210 21f5b45559a59f908ff04df5fbd68a07 174 Gene3D G3DSA:1.20.1290.10 59 174 2.4E-19 T 11-11-2016 IPR029032 AhpD-like Reactome: R-HSA-5628897 AUP74_RS11830 1db94d0caa6ca579c3f64b72580c3d9c 638 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AUP74_RS11830 1db94d0caa6ca579c3f64b72580c3d9c 638 SUPERFAMILY SSF52540 329 511 2.54E-43 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11830 1db94d0caa6ca579c3f64b72580c3d9c 638 Gene3D G3DSA:3.40.50.300 305 539 2.7E-46 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11830 1db94d0caa6ca579c3f64b72580c3d9c 638 ProSitePatterns PS00211 ABC transporters family signature. 436 450 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AUP74_RS11830 1db94d0caa6ca579c3f64b72580c3d9c 638 SMART SM00382 26 214 6.5E-14 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS11830 1db94d0caa6ca579c3f64b72580c3d9c 638 SMART SM00382 339 510 1.1E-13 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS11830 1db94d0caa6ca579c3f64b72580c3d9c 638 Pfam PF00005 ABC transporter 331 464 7.2E-25 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AUP74_RS11830 1db94d0caa6ca579c3f64b72580c3d9c 638 Pfam PF00005 ABC transporter 19 169 3.9E-22 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AUP74_RS11830 1db94d0caa6ca579c3f64b72580c3d9c 638 Pfam PF16326 ABC transporter C-terminal domain 567 635 2.0E-19 T 11-11-2016 IPR032524 ABC transporter Uup, C-terminal GO:0003677 AUP74_RS11830 1db94d0caa6ca579c3f64b72580c3d9c 638 Pfam PF12848 ABC transporter 208 281 1.2E-7 T 11-11-2016 IPR032781 ABC-transporter extension domain AUP74_RS11830 1db94d0caa6ca579c3f64b72580c3d9c 638 SUPERFAMILY SSF52540 2 227 6.64E-43 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11830 1db94d0caa6ca579c3f64b72580c3d9c 638 Gene3D G3DSA:3.40.50.300 2 266 4.1E-46 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS00910 982e8c49f7b7e4fd947335e4b4de4bb0 431 SUPERFAMILY SSF69304 155 428 9.02E-55 T 11-11-2016 AUP74_RS00910 982e8c49f7b7e4fd947335e4b4de4bb0 431 SUPERFAMILY SSF52964 30 160 7.19E-37 T 11-11-2016 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 AUP74_RS00910 982e8c49f7b7e4fd947335e4b4de4bb0 431 Pfam PF07676 WD40-like Beta Propeller Repeat 281 316 3.9E-12 T 11-11-2016 IPR011659 WD40-like Beta Propeller AUP74_RS00910 982e8c49f7b7e4fd947335e4b4de4bb0 431 Pfam PF07676 WD40-like Beta Propeller Repeat 203 228 9.8E-4 T 11-11-2016 IPR011659 WD40-like Beta Propeller AUP74_RS00910 982e8c49f7b7e4fd947335e4b4de4bb0 431 Pfam PF07676 WD40-like Beta Propeller Repeat 237 272 2.0E-10 T 11-11-2016 IPR011659 WD40-like Beta Propeller AUP74_RS00910 982e8c49f7b7e4fd947335e4b4de4bb0 431 Pfam PF04052 TolB amino-terminal domain 26 127 4.7E-28 T 11-11-2016 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 AUP74_RS00910 982e8c49f7b7e4fd947335e4b4de4bb0 431 TIGRFAM TIGR02800 propeller_TolB: Tol-Pal system beta propeller repeat protein TolB 19 427 1.5E-154 T 11-11-2016 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 AUP74_RS00910 982e8c49f7b7e4fd947335e4b4de4bb0 431 Gene3D G3DSA:3.40.50.10070 24 151 5.5E-45 T 11-11-2016 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 AUP74_RS00910 982e8c49f7b7e4fd947335e4b4de4bb0 431 Gene3D G3DSA:2.130.10.10 152 428 1.4E-74 T 11-11-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 AUP74_RS00910 982e8c49f7b7e4fd947335e4b4de4bb0 431 Hamap MF_00671 Protein TolB [tolB]. 4 426 34.292 T 11-11-2016 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 AUP74_RS15400 9dd994af1f3888e97c47975320348657 315 Pfam PF13378 Enolase C-terminal domain-like 129 312 5.4E-31 T 11-11-2016 IPR029065 Enolase C-terminal domain-like AUP74_RS15400 9dd994af1f3888e97c47975320348657 315 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 166 197 - T 11-11-2016 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 AUP74_RS15400 9dd994af1f3888e97c47975320348657 315 SMART SM00922 123 216 1.4E-20 T 11-11-2016 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal AUP74_RS15400 9dd994af1f3888e97c47975320348657 315 Gene3D G3DSA:3.20.20.120 111 308 8.1E-60 T 11-11-2016 IPR029065 Enolase C-terminal domain-like AUP74_RS15400 9dd994af1f3888e97c47975320348657 315 Gene3D G3DSA:3.30.390.10 1 99 6.0E-40 T 11-11-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AUP74_RS15400 9dd994af1f3888e97c47975320348657 315 SUPERFAMILY SSF51604 111 303 3.93E-53 T 11-11-2016 IPR029065 Enolase C-terminal domain-like AUP74_RS15400 9dd994af1f3888e97c47975320348657 315 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 4 103 5.2E-12 T 11-11-2016 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain AUP74_RS15400 9dd994af1f3888e97c47975320348657 315 SUPERFAMILY SSF54826 3 105 7.07E-26 T 11-11-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AUP74_RS07315 7205b81217527c44a5b4bd002c58c688 159 SUPERFAMILY SSF52833 4 159 2.48E-63 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS07315 7205b81217527c44a5b4bd002c58c688 159 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 60 67 - T 11-11-2016 IPR029760 Glutathione peroxidase conserved site Reactome: R-HSA-3299685 AUP74_RS07315 7205b81217527c44a5b4bd002c58c688 159 Gene3D G3DSA:3.40.30.10 4 159 4.7E-73 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS07315 7205b81217527c44a5b4bd002c58c688 159 ProSitePatterns PS00460 Glutathione peroxidases active site. 24 39 - T 11-11-2016 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 AUP74_RS07315 7205b81217527c44a5b4bd002c58c688 159 PIRSF PIRSF000303 1 159 1.0E-66 T 11-11-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 AUP74_RS07315 7205b81217527c44a5b4bd002c58c688 159 Pfam PF00255 Glutathione peroxidase 4 111 2.7E-41 T 11-11-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 AUP74_RS07315 7205b81217527c44a5b4bd002c58c688 159 PRINTS PR01011 Glutathione peroxidase family signature 57 73 1.7E-20 T 11-11-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 AUP74_RS07315 7205b81217527c44a5b4bd002c58c688 159 PRINTS PR01011 Glutathione peroxidase family signature 22 39 1.7E-20 T 11-11-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 AUP74_RS07315 7205b81217527c44a5b4bd002c58c688 159 PRINTS PR01011 Glutathione peroxidase family signature 123 132 1.7E-20 T 11-11-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 AUP74_RS12620 ca811b30136db814f7dc6caa6504024b 442 Gene3D G3DSA:1.10.645.10 3 428 3.5E-88 T 11-11-2016 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS12620 ca811b30136db814f7dc6caa6504024b 442 SUPERFAMILY SSF56762 8 428 4.32E-94 T 11-11-2016 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS12620 ca811b30136db814f7dc6caa6504024b 442 Pfam PF00374 Nickel-dependent hydrogenase 292 428 1.7E-8 T 11-11-2016 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 AUP74_RS12620 ca811b30136db814f7dc6caa6504024b 442 Pfam PF00374 Nickel-dependent hydrogenase 45 130 1.7E-18 T 11-11-2016 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 AUP74_RS12620 ca811b30136db814f7dc6caa6504024b 442 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 419 428 - T 11-11-2016 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 AUP74_RS00995 8b780c11a23341122a1bed6e3b5e0c8d 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 67 6.2E-18 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS00995 8b780c11a23341122a1bed6e3b5e0c8d 308 Pfam PF03466 LysR substrate binding domain 92 301 5.3E-33 T 11-11-2016 IPR005119 LysR, substrate-binding AUP74_RS00995 8b780c11a23341122a1bed6e3b5e0c8d 308 Gene3D G3DSA:3.40.190.10 182 270 1.2E-17 T 11-11-2016 AUP74_RS00995 8b780c11a23341122a1bed6e3b5e0c8d 308 SUPERFAMILY SSF46785 11 115 3.91E-20 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS00995 8b780c11a23341122a1bed6e3b5e0c8d 308 SUPERFAMILY SSF53850 93 304 3.08E-36 T 11-11-2016 AUP74_RS00995 8b780c11a23341122a1bed6e3b5e0c8d 308 Gene3D G3DSA:3.40.190.10 96 181 3.6E-18 T 11-11-2016 AUP74_RS00995 8b780c11a23341122a1bed6e3b5e0c8d 308 Gene3D G3DSA:1.10.10.10 11 87 2.8E-21 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS05690 2703a2d4d41a58ef5172d60af5c92bea 131 SUPERFAMILY SSF52172 6 126 8.82E-37 T 11-11-2016 IPR011006 CheY-like superfamily AUP74_RS05690 2703a2d4d41a58ef5172d60af5c92bea 131 Pfam PF00072 Response regulator receiver domain 10 121 1.5E-27 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS05690 2703a2d4d41a58ef5172d60af5c92bea 131 SMART SM00448 8 121 2.0E-37 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS05690 2703a2d4d41a58ef5172d60af5c92bea 131 Gene3D G3DSA:3.40.50.2300 6 127 1.5E-37 T 11-11-2016 AUP74_RS08610 dfaafb0ac67c816d0099068e96c9ca4b 661 ProSitePatterns PS01303 BCCT family of transporters signature. 316 325 - T 11-11-2016 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 AUP74_RS08610 dfaafb0ac67c816d0099068e96c9ca4b 661 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 16 497 1.5E-189 T 11-11-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 AUP74_RS08610 dfaafb0ac67c816d0099068e96c9ca4b 661 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 54 498 3.4E-159 T 11-11-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 AUP74_RS12120 5dbde4fdb8bc68dba5d18ec0b8d7568b 307 Gene3D G3DSA:3.40.630.10 250 303 3.5E-63 T 11-11-2016 AUP74_RS12120 5dbde4fdb8bc68dba5d18ec0b8d7568b 307 Gene3D G3DSA:3.40.630.10 14 213 3.5E-63 T 11-11-2016 AUP74_RS12120 5dbde4fdb8bc68dba5d18ec0b8d7568b 307 SUPERFAMILY SSF53187 32 289 5.95E-36 T 11-11-2016 AUP74_RS12120 5dbde4fdb8bc68dba5d18ec0b8d7568b 307 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 80 178 1.4E-7 T 11-11-2016 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 AUP74_RS11960 4daa9dc9146f52b19a24fccf48a46c82 154 Pfam PF03061 Thioesterase superfamily 57 145 4.9E-15 T 11-11-2016 IPR006683 Thioesterase domain Reactome: R-HSA-75105 AUP74_RS11960 4daa9dc9146f52b19a24fccf48a46c82 154 SUPERFAMILY SSF54637 5 153 3.57E-24 T 11-11-2016 IPR029069 HotDog domain AUP74_RS11960 4daa9dc9146f52b19a24fccf48a46c82 154 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 27 152 7.0E-11 T 11-11-2016 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 AUP74_RS11960 4daa9dc9146f52b19a24fccf48a46c82 154 Gene3D G3DSA:3.10.129.10 9 153 2.8E-29 T 11-11-2016 IPR029069 HotDog domain AUP74_RS01230 27575d1e4408d6b2cb270e5fe930509e 218 Gene3D G3DSA:2.60.120.10 128 217 1.2E-26 T 11-11-2016 IPR014710 RmlC-like jelly roll fold AUP74_RS01230 27575d1e4408d6b2cb270e5fe930509e 218 Gene3D G3DSA:2.60.120.10 18 127 8.3E-40 T 11-11-2016 IPR014710 RmlC-like jelly roll fold AUP74_RS01230 27575d1e4408d6b2cb270e5fe930509e 218 SUPERFAMILY SSF51182 119 218 2.24E-23 T 11-11-2016 IPR011051 RmlC-like cupin domain AUP74_RS01230 27575d1e4408d6b2cb270e5fe930509e 218 Pfam PF12973 ChrR Cupin-like domain 128 215 5.5E-31 T 11-11-2016 IPR025979 ChrR-like cupin domain AUP74_RS01230 27575d1e4408d6b2cb270e5fe930509e 218 Pfam PF12973 ChrR Cupin-like domain 19 110 4.7E-38 T 11-11-2016 IPR025979 ChrR-like cupin domain AUP74_RS01230 27575d1e4408d6b2cb270e5fe930509e 218 SUPERFAMILY SSF51182 3 131 3.67E-36 T 11-11-2016 IPR011051 RmlC-like cupin domain AUP74_RS06850 e49527ebe4d23e918c2ae9ad5e69d12e 110 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 28.696 T 11-11-2016 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06850 e49527ebe4d23e918c2ae9ad5e69d12e 110 SUPERFAMILY SSF54843 1 110 2.88E-43 T 11-11-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 AUP74_RS06850 e49527ebe4d23e918c2ae9ad5e69d12e 110 Gene3D G3DSA:3.90.470.10 1 110 4.3E-44 T 11-11-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 AUP74_RS06850 e49527ebe4d23e918c2ae9ad5e69d12e 110 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 11-11-2016 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06850 e49527ebe4d23e918c2ae9ad5e69d12e 110 Pfam PF00237 Ribosomal protein L22p/L17e 9 107 2.8E-34 T 11-11-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 AUP74_RS06850 e49527ebe4d23e918c2ae9ad5e69d12e 110 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 2.5E-47 T 11-11-2016 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS09370 6e28303fec1ca48cbc9f1011b5174e81 151 Pfam PF14437 MafB19-like deaminase 9 149 2.5E-31 T 11-11-2016 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 AUP74_RS09370 6e28303fec1ca48cbc9f1011b5174e81 151 SUPERFAMILY SSF53927 4 151 1.84E-54 T 11-11-2016 IPR016193 Cytidine deaminase-like GO:0003824 AUP74_RS09370 6e28303fec1ca48cbc9f1011b5174e81 151 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 10 151 44.668 T 11-11-2016 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 AUP74_RS09370 6e28303fec1ca48cbc9f1011b5174e81 151 Gene3D G3DSA:3.40.140.10 3 149 2.9E-55 T 11-11-2016 AUP74_RS09370 6e28303fec1ca48cbc9f1011b5174e81 151 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 55 92 - T 11-11-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 AUP74_RS10540 26f8291ca27aa7f5cbb1f549d6192d96 316 SUPERFAMILY SSF47807 181 300 1.79E-24 T 11-11-2016 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 AUP74_RS10540 26f8291ca27aa7f5cbb1f549d6192d96 316 SMART SM00475 18 278 4.1E-75 T 11-11-2016 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 AUP74_RS10540 26f8291ca27aa7f5cbb1f549d6192d96 316 SMART SM00279 183 218 4.9E-13 T 11-11-2016 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 AUP74_RS10540 26f8291ca27aa7f5cbb1f549d6192d96 316 Gene3D G3DSA:1.10.150.20 196 262 5.5E-24 T 11-11-2016 AUP74_RS10540 26f8291ca27aa7f5cbb1f549d6192d96 316 Gene3D G3DSA:3.40.50.1010 20 195 2.8E-47 T 11-11-2016 IPR029060 PIN domain-like AUP74_RS10540 26f8291ca27aa7f5cbb1f549d6192d96 316 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 20 180 5.2E-37 T 11-11-2016 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 AUP74_RS10540 26f8291ca27aa7f5cbb1f549d6192d96 316 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 181 281 7.7E-28 T 11-11-2016 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 AUP74_RS10540 26f8291ca27aa7f5cbb1f549d6192d96 316 SUPERFAMILY SSF88723 19 169 1.18E-38 T 11-11-2016 IPR029060 PIN domain-like AUP74_RS15360 c00954f1ced5190a638e4c9e0ac2bc8f 140 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 35 124 4.2E-23 T 11-11-2016 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 AUP74_RS15360 c00954f1ced5190a638e4c9e0ac2bc8f 140 Gene3D G3DSA:3.90.1590.10 13 139 1.8E-32 T 11-11-2016 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 AUP74_RS15360 c00954f1ced5190a638e4c9e0ac2bc8f 140 SUPERFAMILY SSF51316 10 139 3.35E-37 T 11-11-2016 IPR011057 Mss4-like AUP74_RS09355 34ea300ff1f1e1f152def74b0df55384 228 Pfam PF13847 Methyltransferase domain 53 154 4.2E-15 T 11-11-2016 IPR025714 Methyltransferase domain AUP74_RS09355 34ea300ff1f1e1f152def74b0df55384 228 SUPERFAMILY SSF53335 13 207 7.37E-27 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS09355 34ea300ff1f1e1f152def74b0df55384 228 Gene3D G3DSA:3.40.50.150 10 203 2.1E-23 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS13820 e4c797508a1183ad7a00598ba7956ded 165 Gene3D G3DSA:1.10.10.10 13 155 1.2E-37 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS13820 e4c797508a1183ad7a00598ba7956ded 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 82 97 1.5E-8 T 11-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AUP74_RS13820 e4c797508a1183ad7a00598ba7956ded 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 131 151 1.5E-8 T 11-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AUP74_RS13820 e4c797508a1183ad7a00598ba7956ded 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 81 1.5E-8 T 11-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AUP74_RS13820 e4c797508a1183ad7a00598ba7956ded 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 101 117 1.5E-8 T 11-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AUP74_RS13820 e4c797508a1183ad7a00598ba7956ded 165 SMART SM00347 41 141 2.0E-20 T 11-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AUP74_RS13820 e4c797508a1183ad7a00598ba7956ded 165 Pfam PF12802 MarR family 48 105 1.3E-10 T 11-11-2016 AUP74_RS13820 e4c797508a1183ad7a00598ba7956ded 165 SUPERFAMILY SSF46785 13 157 5.2E-31 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS05535 2e7f24ddbc7e8d7ddeaff52cf3cff364 205 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 2 196 49.421 T 11-11-2016 IPR020922 Non-canonical purine NTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 AUP74_RS05535 2e7f24ddbc7e8d7ddeaff52cf3cff364 205 SUPERFAMILY SSF52972 3 195 2.88E-69 T 11-11-2016 IPR029001 Inosine triphosphate pyrophosphatase-like AUP74_RS05535 2e7f24ddbc7e8d7ddeaff52cf3cff364 205 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 3 194 1.3E-54 T 11-11-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206|Reactome: R-HSA-15869 AUP74_RS05535 2e7f24ddbc7e8d7ddeaff52cf3cff364 205 Pfam PF01725 Ham1 family 4 191 2.4E-52 T 11-11-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206|Reactome: R-HSA-15869 AUP74_RS05535 2e7f24ddbc7e8d7ddeaff52cf3cff364 205 Gene3D G3DSA:3.90.950.10 3 196 1.1E-76 T 11-11-2016 IPR029001 Inosine triphosphate pyrophosphatase-like AUP74_RS00195 184201c8ec26f3468bd5d279a65bbc8e 212 SUPERFAMILY SSF50715 4 198 1.15E-56 T 11-11-2016 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AUP74_RS00195 184201c8ec26f3468bd5d279a65bbc8e 212 Gene3D G3DSA:2.170.120.20 100 198 1.8E-31 T 11-11-2016 IPR020057 Ribosomal protein L25, beta domain AUP74_RS00195 184201c8ec26f3468bd5d279a65bbc8e 212 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 6 174 2.7E-45 T 11-11-2016 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 AUP74_RS00195 184201c8ec26f3468bd5d279a65bbc8e 212 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 4 189 30.193 T 11-11-2016 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 AUP74_RS00195 184201c8ec26f3468bd5d279a65bbc8e 212 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 8 97 4.0E-25 T 11-11-2016 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 AUP74_RS00195 184201c8ec26f3468bd5d279a65bbc8e 212 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 102 192 5.0E-30 T 11-11-2016 IPR020057 Ribosomal protein L25, beta domain AUP74_RS00195 184201c8ec26f3468bd5d279a65bbc8e 212 Gene3D G3DSA:2.40.240.10 4 97 1.2E-33 T 11-11-2016 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AUP74_RS00195 184201c8ec26f3468bd5d279a65bbc8e 212 Hamap MF_01336 50S ribosomal protein L25 [rplY]. 4 97 21.491 T 11-11-2016 IPR020055 Ribosomal protein L25, short-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 AUP74_RS00195 184201c8ec26f3468bd5d279a65bbc8e 212 Pfam PF01386 Ribosomal L25p family 6 94 3.7E-26 T 11-11-2016 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 AUP74_RS06805 05affa8f2a513fca2724e0b56503fb70 701 Gene3D G3DSA:3.30.70.240 611 698 2.0E-32 T 11-11-2016 IPR000640 Translation elongation factor EFG, V domain AUP74_RS06805 05affa8f2a513fca2724e0b56503fb70 701 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 186 3.2E-34 T 11-11-2016 IPR005225 Small GTP-binding protein domain GO:0005525 AUP74_RS06805 05affa8f2a513fca2724e0b56503fb70 701 PRINTS PR00315 GTP-binding elongation factor signature 101 112 9.6E-17 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AUP74_RS06805 05affa8f2a513fca2724e0b56503fb70 701 PRINTS PR00315 GTP-binding elongation factor signature 85 95 9.6E-17 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AUP74_RS06805 05affa8f2a513fca2724e0b56503fb70 701 PRINTS PR00315 GTP-binding elongation factor signature 137 146 9.6E-17 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AUP74_RS06805 05affa8f2a513fca2724e0b56503fb70 701 PRINTS PR00315 GTP-binding elongation factor signature 12 25 9.6E-17 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AUP74_RS06805 05affa8f2a513fca2724e0b56503fb70 701 PRINTS PR00315 GTP-binding elongation factor signature 58 66 9.6E-17 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AUP74_RS06805 05affa8f2a513fca2724e0b56503fb70 701 TIGRFAM TIGR00484 EF-G: translation elongation factor G 2 700 0.0 T 11-11-2016 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AUP74_RS06805 05affa8f2a513fca2724e0b56503fb70 701 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 11-11-2016 IPR031157 Tr-type G domain, conserved site AUP74_RS06805 05affa8f2a513fca2724e0b56503fb70 701 Gene3D G3DSA:3.30.70.870 412 486 1.7E-39 T 11-11-2016 AUP74_RS06805 05affa8f2a513fca2724e0b56503fb70 701 Pfam PF14492 Elongation Factor G, domain II 410 484 8.7E-35 T 11-11-2016 IPR009022 Elongation factor G, III-V domain AUP74_RS06805 05affa8f2a513fca2724e0b56503fb70 701 SUPERFAMILY SSF54980 611 698 2.73E-30 T 11-11-2016 IPR009022 Elongation factor G, III-V domain AUP74_RS06805 05affa8f2a513fca2724e0b56503fb70 701 Pfam PF00679 Elongation factor G C-terminus 608 694 8.0E-31 T 11-11-2016 IPR000640 Translation elongation factor EFG, V domain AUP74_RS06805 05affa8f2a513fca2724e0b56503fb70 701 SMART SM00838 608 695 2.8E-60 T 11-11-2016 IPR000640 Translation elongation factor EFG, V domain AUP74_RS06805 05affa8f2a513fca2724e0b56503fb70 701 SUPERFAMILY SSF54211 485 603 3.03E-42 T 11-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold AUP74_RS06805 05affa8f2a513fca2724e0b56503fb70 701 Gene3D G3DSA:3.30.230.10 490 610 6.5E-48 T 11-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AUP74_RS06805 05affa8f2a513fca2724e0b56503fb70 701 Gene3D G3DSA:3.40.50.300 6 292 9.5E-105 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS06805 05affa8f2a513fca2724e0b56503fb70 701 Pfam PF03764 Elongation factor G, domain IV 485 603 3.6E-44 T 11-11-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 AUP74_RS06805 05affa8f2a513fca2724e0b56503fb70 701 Hamap MF_00054_B Elongation factor G [fusA]. 6 699 110.574 T 11-11-2016 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AUP74_RS06805 05affa8f2a513fca2724e0b56503fb70 701 SUPERFAMILY SSF52540 6 287 9.14E-108 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS06805 05affa8f2a513fca2724e0b56503fb70 701 SMART SM00889 486 606 3.0E-70 T 11-11-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 AUP74_RS06805 05affa8f2a513fca2724e0b56503fb70 701 SUPERFAMILY SSF50447 271 410 6.06E-34 T 11-11-2016 IPR009000 Translation protein, beta-barrel domain AUP74_RS06805 05affa8f2a513fca2724e0b56503fb70 701 Gene3D G3DSA:2.40.30.10 311 411 2.7E-37 T 11-11-2016 AUP74_RS06805 05affa8f2a513fca2724e0b56503fb70 701 Pfam PF03144 Elongation factor Tu domain 2 330 397 1.8E-15 T 11-11-2016 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AUP74_RS06805 05affa8f2a513fca2724e0b56503fb70 701 Pfam PF00009 Elongation factor Tu GTP binding domain 9 287 1.7E-68 T 11-11-2016 AUP74_RS06805 05affa8f2a513fca2724e0b56503fb70 701 SUPERFAMILY SSF54980 410 487 1.19E-25 T 11-11-2016 IPR009022 Elongation factor G, III-V domain AUP74_RS11165 828cdc77f612dca1266f6f06a06a14bb 224 Pfam PF13489 Methyltransferase domain 68 200 1.0E-19 T 11-11-2016 AUP74_RS11165 828cdc77f612dca1266f6f06a06a14bb 224 SUPERFAMILY SSF53335 54 201 1.62E-20 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS11165 828cdc77f612dca1266f6f06a06a14bb 224 Gene3D G3DSA:3.40.50.150 73 202 1.2E-14 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS12645 fce7d0b83603497a2f9f6b2312b245e9 179 Pfam PF00583 Acetyltransferase (GNAT) family 92 162 1.8E-5 T 11-11-2016 IPR000182 GNAT domain GO:0008080 AUP74_RS12645 fce7d0b83603497a2f9f6b2312b245e9 179 SUPERFAMILY SSF55729 26 164 9.41E-18 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS12645 fce7d0b83603497a2f9f6b2312b245e9 179 Gene3D G3DSA:3.40.630.30 17 169 2.1E-16 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS07185 0372892db68ccdc62e4160b7b21834c5 254 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 29 252 2.1E-62 T 11-11-2016 IPR003730 Multi-copper polyphenol oxidoreductase, laccase AUP74_RS07185 0372892db68ccdc62e4160b7b21834c5 254 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 22 251 1.1E-72 T 11-11-2016 IPR003730 Multi-copper polyphenol oxidoreductase, laccase AUP74_RS07185 0372892db68ccdc62e4160b7b21834c5 254 Gene3D G3DSA:3.60.140.10 4 253 1.6E-93 T 11-11-2016 IPR003730 Multi-copper polyphenol oxidoreductase, laccase AUP74_RS07185 0372892db68ccdc62e4160b7b21834c5 254 SUPERFAMILY SSF64438 4 253 4.94E-81 T 11-11-2016 IPR011324 Cytotoxic necrotizing factor-like, catalytic AUP74_RS10065 4602442810ed0413ddb4f35c69367384 545 SUPERFAMILY SSF52540 1 268 1.11E-119 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS10065 4602442810ed0413ddb4f35c69367384 545 Gene3D G3DSA:3.40.50.880 286 541 2.9E-98 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS10065 4602442810ed0413ddb4f35c69367384 545 Hamap MF_01227 CTP synthase [pyrG]. 2 540 51.063 T 11-11-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 AUP74_RS10065 4602442810ed0413ddb4f35c69367384 545 Gene3D G3DSA:3.40.50.300 1 279 7.5E-130 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS10065 4602442810ed0413ddb4f35c69367384 545 Pfam PF00117 Glutamine amidotransferase class-I 300 534 6.9E-59 T 11-11-2016 IPR017926 Glutamine amidotransferase AUP74_RS10065 4602442810ed0413ddb4f35c69367384 545 Pfam PF06418 CTP synthase N-terminus 3 265 4.4E-123 T 11-11-2016 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 AUP74_RS10065 4602442810ed0413ddb4f35c69367384 545 SUPERFAMILY SSF52317 287 542 1.12E-86 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS10065 4602442810ed0413ddb4f35c69367384 545 TIGRFAM TIGR00337 PyrG: CTP synthase 2 535 1.2E-246 T 11-11-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 AUP74_RS04330 c0a5805b37a63ba8726b219894bc6148 609 SUPERFAMILY SSF56235 2 235 1.46E-74 T 11-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal AUP74_RS04330 c0a5805b37a63ba8726b219894bc6148 609 Gene3D G3DSA:3.40.50.10490 444 609 4.3E-64 T 11-11-2016 AUP74_RS04330 c0a5805b37a63ba8726b219894bc6148 609 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 609 40.12 T 11-11-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 AUP74_RS04330 c0a5805b37a63ba8726b219894bc6148 609 SUPERFAMILY SSF53697 245 609 2.5E-111 T 11-11-2016 AUP74_RS04330 c0a5805b37a63ba8726b219894bc6148 609 Gene3D G3DSA:3.60.20.10 2 235 1.2E-78 T 11-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal AUP74_RS04330 c0a5805b37a63ba8726b219894bc6148 609 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 609 6.6E-254 T 11-11-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 AUP74_RS04330 c0a5805b37a63ba8726b219894bc6148 609 Pfam PF01380 SIS domain 462 591 7.0E-25 T 11-11-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 AUP74_RS04330 c0a5805b37a63ba8726b219894bc6148 609 Pfam PF01380 SIS domain 292 418 2.1E-31 T 11-11-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 AUP74_RS04330 c0a5805b37a63ba8726b219894bc6148 609 Pfam PF13522 Glutamine amidotransferase domain 65 184 4.9E-23 T 11-11-2016 AUP74_RS04330 c0a5805b37a63ba8726b219894bc6148 609 Gene3D G3DSA:3.40.50.10490 244 443 1.4E-68 T 11-11-2016 AUP74_RS09710 75d489e0174ce54b4318bca73f56027a 335 Pfam PF13343 Bacterial extracellular solute-binding protein 65 302 1.8E-20 T 11-11-2016 AUP74_RS09710 75d489e0174ce54b4318bca73f56027a 335 Gene3D G3DSA:3.40.190.10 265 299 1.4E-28 T 11-11-2016 AUP74_RS09710 75d489e0174ce54b4318bca73f56027a 335 Gene3D G3DSA:3.40.190.10 3 114 1.4E-28 T 11-11-2016 AUP74_RS09710 75d489e0174ce54b4318bca73f56027a 335 PIRSF PIRSF002825 1 335 1.2E-87 T 11-11-2016 IPR026045 Ferric binding protein AUP74_RS09710 75d489e0174ce54b4318bca73f56027a 335 SUPERFAMILY SSF53850 15 330 2.52E-75 T 11-11-2016 AUP74_RS09710 75d489e0174ce54b4318bca73f56027a 335 Gene3D G3DSA:3.40.190.10 118 264 8.3E-54 T 11-11-2016 AUP74_RS10910 47ef7e4f76627891e6e810895741e479 202 Gene3D G3DSA:3.30.70.240 137 188 6.2E-8 T 11-11-2016 IPR000640 Translation elongation factor EFG, V domain AUP74_RS10910 47ef7e4f76627891e6e810895741e479 202 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 79 108 - T 11-11-2016 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site AUP74_RS10910 47ef7e4f76627891e6e810895741e479 202 Pfam PF09186 Domain of unknown function (DUF1949) 140 185 1.0E-7 T 11-11-2016 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal AUP74_RS10910 47ef7e4f76627891e6e810895741e479 202 Gene3D G3DSA:3.30.230.30 3 129 4.5E-39 T 11-11-2016 IPR001498 Impact, N-terminal AUP74_RS10910 47ef7e4f76627891e6e810895741e479 202 SUPERFAMILY SSF54980 136 188 7.91E-9 T 11-11-2016 IPR009022 Elongation factor G, III-V domain AUP74_RS10910 47ef7e4f76627891e6e810895741e479 202 SUPERFAMILY SSF54211 3 130 2.24E-38 T 11-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold AUP74_RS10910 47ef7e4f76627891e6e810895741e479 202 Pfam PF01205 Uncharacterized protein family UPF0029 17 124 1.1E-25 T 11-11-2016 IPR001498 Impact, N-terminal AUP74_RS12905 56ee333491ef5d36d048996752de316a 710 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 405 705 3.1E-131 T 11-11-2016 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 AUP74_RS12905 56ee333491ef5d36d048996752de316a 710 SUPERFAMILY SSF75138 228 351 6.47E-26 T 11-11-2016 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like AUP74_RS12905 56ee333491ef5d36d048996752de316a 710 SUPERFAMILY SSF53659 391 708 1.93E-94 T 11-11-2016 AUP74_RS12905 56ee333491ef5d36d048996752de316a 710 Gene3D G3DSA:3.40.50.300 14 222 3.1E-9 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS12905 56ee333491ef5d36d048996752de316a 710 PIRSF PIRSF006107 1 710 0.0 T 11-11-2016 IPR016475 Phosphate acetyltransferase, bacteria GO:0008959 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 AUP74_RS12905 56ee333491ef5d36d048996752de316a 710 Pfam PF13500 AAA domain 3 228 1.9E-32 T 11-11-2016 AUP74_RS12905 56ee333491ef5d36d048996752de316a 710 Pfam PF07085 DRTGG domain 232 343 1.4E-28 T 11-11-2016 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 AUP74_RS12905 56ee333491ef5d36d048996752de316a 710 Pfam PF01515 Phosphate acetyl/butaryl transferase 390 705 8.9E-126 T 11-11-2016 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 AUP74_RS12905 56ee333491ef5d36d048996752de316a 710 Gene3D G3DSA:3.40.1390.20 224 364 6.3E-32 T 11-11-2016 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like AUP74_RS12905 56ee333491ef5d36d048996752de316a 710 Gene3D G3DSA:3.40.50.10750 522 681 2.2E-66 T 11-11-2016 AUP74_RS12905 56ee333491ef5d36d048996752de316a 710 SUPERFAMILY SSF52540 4 239 3.56E-20 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11815 74dfc0fa8a4e0ec67f775baa14770dff 294 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 11 93 5.7E-12 T 11-11-2016 IPR032030 YscD, cytoplasmic domain AUP74_RS11815 74dfc0fa8a4e0ec67f775baa14770dff 294 SUPERFAMILY SSF49879 11 89 6.12E-14 T 11-11-2016 IPR008984 SMAD/FHA domain GO:0005515 AUP74_RS11815 74dfc0fa8a4e0ec67f775baa14770dff 294 Gene3D G3DSA:2.60.200.20 14 91 1.7E-14 T 11-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 AUP74_RS11815 74dfc0fa8a4e0ec67f775baa14770dff 294 Pfam PF00498 FHA domain 131 192 1.1E-16 T 11-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 AUP74_RS11815 74dfc0fa8a4e0ec67f775baa14770dff 294 SMART SM00240 20 70 1.0 T 11-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 AUP74_RS11815 74dfc0fa8a4e0ec67f775baa14770dff 294 SMART SM00240 129 179 5.9E-14 T 11-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 AUP74_RS11815 74dfc0fa8a4e0ec67f775baa14770dff 294 Gene3D G3DSA:2.60.200.20 104 200 1.8E-22 T 11-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 AUP74_RS11815 74dfc0fa8a4e0ec67f775baa14770dff 294 SUPERFAMILY SSF49879 105 211 1.42E-22 T 11-11-2016 IPR008984 SMAD/FHA domain GO:0005515 AUP74_RS04970 2d06464e6cc140c560aa505bbdd6afd1 319 Gene3D G3DSA:1.10.287.110 1 114 1.6E-33 T 11-11-2016 IPR001623 DnaJ domain AUP74_RS04970 2d06464e6cc140c560aa505bbdd6afd1 319 Gene3D G3DSA:2.60.260.20 217 291 2.2E-13 T 11-11-2016 AUP74_RS04970 2d06464e6cc140c560aa505bbdd6afd1 319 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 11-11-2016 IPR018253 DnaJ domain, conserved site AUP74_RS04970 2d06464e6cc140c560aa505bbdd6afd1 319 SMART SM00271 4 61 3.6E-29 T 11-11-2016 IPR001623 DnaJ domain AUP74_RS04970 2d06464e6cc140c560aa505bbdd6afd1 319 Gene3D G3DSA:2.60.260.20 128 213 1.1E-19 T 11-11-2016 AUP74_RS04970 2d06464e6cc140c560aa505bbdd6afd1 319 SUPERFAMILY SSF49493 220 302 2.09E-16 T 11-11-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 AUP74_RS04970 2d06464e6cc140c560aa505bbdd6afd1 319 Pfam PF01556 DnaJ C terminal domain 139 291 5.5E-32 T 11-11-2016 IPR002939 Chaperone DnaJ, C-terminal AUP74_RS04970 2d06464e6cc140c560aa505bbdd6afd1 319 PRINTS PR00625 DnaJ domain signature 7 25 4.6E-26 T 11-11-2016 IPR001623 DnaJ domain AUP74_RS04970 2d06464e6cc140c560aa505bbdd6afd1 319 PRINTS PR00625 DnaJ domain signature 41 61 4.6E-26 T 11-11-2016 IPR001623 DnaJ domain AUP74_RS04970 2d06464e6cc140c560aa505bbdd6afd1 319 PRINTS PR00625 DnaJ domain signature 61 80 4.6E-26 T 11-11-2016 IPR001623 DnaJ domain AUP74_RS04970 2d06464e6cc140c560aa505bbdd6afd1 319 PRINTS PR00625 DnaJ domain signature 25 40 4.6E-26 T 11-11-2016 IPR001623 DnaJ domain AUP74_RS04970 2d06464e6cc140c560aa505bbdd6afd1 319 Pfam PF00226 DnaJ domain 5 66 3.1E-26 T 11-11-2016 IPR001623 DnaJ domain AUP74_RS04970 2d06464e6cc140c560aa505bbdd6afd1 319 SUPERFAMILY SSF46565 1 118 5.36E-32 T 11-11-2016 IPR001623 DnaJ domain AUP74_RS04970 2d06464e6cc140c560aa505bbdd6afd1 319 SUPERFAMILY SSF49493 130 225 1.44E-16 T 11-11-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 AUP74_RS11235 7c32d849cf7c347cfca3626f8b652510 255 TIGRFAM TIGR03413 GSH_gloB: hydroxyacylglutathione hydrolase 4 255 4.7E-98 T 11-11-2016 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 AUP74_RS11235 7c32d849cf7c347cfca3626f8b652510 255 Pfam PF00753 Metallo-beta-lactamase superfamily 16 167 1.2E-11 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS11235 7c32d849cf7c347cfca3626f8b652510 255 SMART SM00849 12 167 2.2E-32 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS11235 7c32d849cf7c347cfca3626f8b652510 255 Pfam PF16123 Hydroxyacylglutathione hydrolase C-terminus 168 255 7.1E-29 T 11-11-2016 IPR032282 Hydroxyacylglutathione hydrolase, C-terminal domain KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 AUP74_RS11235 7c32d849cf7c347cfca3626f8b652510 255 Hamap MF_01374 Hydroxyacylglutathione hydrolase [gloB]. 2 255 42.478 T 11-11-2016 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 AUP74_RS11235 7c32d849cf7c347cfca3626f8b652510 255 PIRSF PIRSF005457 1 255 2.7E-95 T 11-11-2016 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 AUP74_RS11235 7c32d849cf7c347cfca3626f8b652510 255 SUPERFAMILY SSF56281 3 255 4.06E-71 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS11235 7c32d849cf7c347cfca3626f8b652510 255 Gene3D G3DSA:3.60.15.10 4 255 5.0E-88 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS16565 38cfd1276fea800dda9c779afc159e88 234 Gene3D G3DSA:3.10.20.30 2 103 7.9E-36 T 11-11-2016 IPR012675 Beta-grasp domain AUP74_RS16565 38cfd1276fea800dda9c779afc159e88 234 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 6 226 2.0E-85 T 11-11-2016 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 AUP74_RS16565 38cfd1276fea800dda9c779afc159e88 234 Gene3D G3DSA:1.10.1060.10 104 232 2.2E-48 T 11-11-2016 AUP74_RS16565 38cfd1276fea800dda9c779afc159e88 234 SUPERFAMILY SSF46548 104 230 5.58E-39 T 11-11-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 AUP74_RS16565 38cfd1276fea800dda9c779afc159e88 234 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 145 156 - T 11-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AUP74_RS16565 38cfd1276fea800dda9c779afc159e88 234 SUPERFAMILY SSF54292 2 103 8.61E-26 T 11-11-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AUP74_RS16565 38cfd1276fea800dda9c779afc159e88 234 Pfam PF13534 4Fe-4S dicluster domain 144 217 8.0E-10 T 11-11-2016 AUP74_RS16565 38cfd1276fea800dda9c779afc159e88 234 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 4 108 1.5E-31 T 11-11-2016 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 AUP74_RS12020 e610ffbc221b849d469760f661462525 251 SMART SM00382 52 242 1.8E-14 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS12020 e610ffbc221b849d469760f661462525 251 TIGRFAM TIGR02211 LolD_lipo_ex: lipoprotein releasing system, ATP-binding protein 23 242 8.8E-97 T 11-11-2016 IPR011924 Lipoprotein releasing system, ATP-binding protein GO:0005524|GO:0006810|GO:0016020 AUP74_RS12020 e610ffbc221b849d469760f661462525 251 Pfam PF00005 ABC transporter 43 191 4.1E-31 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AUP74_RS12020 e610ffbc221b849d469760f661462525 251 Gene3D G3DSA:3.40.50.300 23 243 1.1E-66 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS12020 e610ffbc221b849d469760f661462525 251 SUPERFAMILY SSF52540 24 245 3.12E-68 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS12020 e610ffbc221b849d469760f661462525 251 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AUP74_RS06240 8540747602d6ee536a6366b11233dfac 429 Pfam PF12404 Peptidase 5 83 1.2E-26 T 11-11-2016 IPR008330 Peptidase M17, peptidase B GO:0004177|GO:0005737|GO:0006508|GO:0008235|GO:0030145 KEGG: 00480+3.4.11.23 AUP74_RS06240 8540747602d6ee536a6366b11233dfac 429 Gene3D G3DSA:3.40.630.10 97 428 3.2E-109 T 11-11-2016 AUP74_RS06240 8540747602d6ee536a6366b11233dfac 429 SUPERFAMILY SSF53187 108 428 1.1E-96 T 11-11-2016 AUP74_RS06240 8540747602d6ee536a6366b11233dfac 429 PRINTS PR00481 Cytosol aminopeptidase signature 214 235 1.9E-43 T 11-11-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 AUP74_RS06240 8540747602d6ee536a6366b11233dfac 429 PRINTS PR00481 Cytosol aminopeptidase signature 251 272 1.9E-43 T 11-11-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 AUP74_RS06240 8540747602d6ee536a6366b11233dfac 429 PRINTS PR00481 Cytosol aminopeptidase signature 192 209 1.9E-43 T 11-11-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 AUP74_RS06240 8540747602d6ee536a6366b11233dfac 429 PRINTS PR00481 Cytosol aminopeptidase signature 273 293 1.9E-43 T 11-11-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 AUP74_RS06240 8540747602d6ee536a6366b11233dfac 429 PRINTS PR00481 Cytosol aminopeptidase signature 301 316 1.9E-43 T 11-11-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 AUP74_RS06240 8540747602d6ee536a6366b11233dfac 429 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 277 284 - T 11-11-2016 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 AUP74_RS06240 8540747602d6ee536a6366b11233dfac 429 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 111 422 1.3E-94 T 11-11-2016 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 AUP74_RS06240 8540747602d6ee536a6366b11233dfac 429 PIRSF PIRSF036388 1 429 1.9E-185 T 11-11-2016 IPR008330 Peptidase M17, peptidase B GO:0004177|GO:0005737|GO:0006508|GO:0008235|GO:0030145 KEGG: 00480+3.4.11.23 AUP74_RS00410 acca86689e127986003da84c72470bef 865 SUPERFAMILY SSF47323 665 864 4.49E-37 T 11-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS00410 acca86689e127986003da84c72470bef 865 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 53 - T 11-11-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS00410 acca86689e127986003da84c72470bef 865 PRINTS PR00985 Leucyl-tRNA synthetase signature 488 506 4.5E-53 T 11-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AUP74_RS00410 acca86689e127986003da84c72470bef 865 PRINTS PR00985 Leucyl-tRNA synthetase signature 185 198 4.5E-53 T 11-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AUP74_RS00410 acca86689e127986003da84c72470bef 865 PRINTS PR00985 Leucyl-tRNA synthetase signature 527 549 4.5E-53 T 11-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AUP74_RS00410 acca86689e127986003da84c72470bef 865 PRINTS PR00985 Leucyl-tRNA synthetase signature 215 234 4.5E-53 T 11-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AUP74_RS00410 acca86689e127986003da84c72470bef 865 PRINTS PR00985 Leucyl-tRNA synthetase signature 560 570 4.5E-53 T 11-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AUP74_RS00410 acca86689e127986003da84c72470bef 865 PRINTS PR00985 Leucyl-tRNA synthetase signature 127 144 4.5E-53 T 11-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AUP74_RS00410 acca86689e127986003da84c72470bef 865 PRINTS PR00985 Leucyl-tRNA synthetase signature 153 169 4.5E-53 T 11-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AUP74_RS00410 acca86689e127986003da84c72470bef 865 Gene3D G3DSA:3.40.50.620 3 222 1.4E-154 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS00410 acca86689e127986003da84c72470bef 865 Gene3D G3DSA:3.40.50.620 428 576 1.4E-154 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS00410 acca86689e127986003da84c72470bef 865 Gene3D G3DSA:3.40.50.620 621 650 1.4E-154 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS00410 acca86689e127986003da84c72470bef 865 Gene3D G3DSA:3.90.740.10 223 427 1.1E-57 T 11-11-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AUP74_RS00410 acca86689e127986003da84c72470bef 865 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 5 865 0.0 T 11-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AUP74_RS00410 acca86689e127986003da84c72470bef 865 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 15 172 2.8E-29 T 11-11-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS00410 acca86689e127986003da84c72470bef 865 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 622 658 3.7E-5 T 11-11-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS00410 acca86689e127986003da84c72470bef 865 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 421 593 1.1E-10 T 11-11-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS00410 acca86689e127986003da84c72470bef 865 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 4 864 23.666 T 11-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AUP74_RS00410 acca86689e127986003da84c72470bef 865 Pfam PF08264 Anticodon-binding domain of tRNA 705 826 2.8E-15 T 11-11-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 AUP74_RS00410 acca86689e127986003da84c72470bef 865 SUPERFAMILY SSF52374 4 226 7.8E-146 T 11-11-2016 AUP74_RS00410 acca86689e127986003da84c72470bef 865 SUPERFAMILY SSF52374 419 670 7.8E-146 T 11-11-2016 AUP74_RS00410 acca86689e127986003da84c72470bef 865 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 221 406 1.5E-77 T 11-11-2016 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 AUP74_RS00410 acca86689e127986003da84c72470bef 865 SUPERFAMILY SSF50677 226 418 1.47E-55 T 11-11-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AUP74_RS00410 acca86689e127986003da84c72470bef 865 Gene3D G3DSA:1.10.730.10 651 800 4.9E-44 T 11-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS08195 2bfc146dae06115aa9c2a87c35eec208 917 SUPERFAMILY SSF50447 592 672 1.81E-23 T 11-11-2016 IPR009000 Translation protein, beta-barrel domain AUP74_RS08195 2bfc146dae06115aa9c2a87c35eec208 917 Pfam PF08364 Bacterial translation initiation factor IF-2 associated region 61 98 3.8E-13 T 11-11-2016 IPR013575 Initiation factor 2 associated domain, bacterial AUP74_RS08195 2bfc146dae06115aa9c2a87c35eec208 917 Pfam PF00009 Elongation factor Tu GTP binding domain 422 577 2.8E-33 T 11-11-2016 AUP74_RS08195 2bfc146dae06115aa9c2a87c35eec208 917 Gene3D G3DSA:3.40.50.10050 718 796 1.0E-23 T 11-11-2016 IPR023115 Translation initiation factor IF- 2, domain 3 AUP74_RS08195 2bfc146dae06115aa9c2a87c35eec208 917 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 915 17.342 T 11-11-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 AUP74_RS08195 2bfc146dae06115aa9c2a87c35eec208 917 Gene3D G3DSA:3.40.50.300 411 576 4.7E-47 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS08195 2bfc146dae06115aa9c2a87c35eec208 917 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 336 915 1.3E-258 T 11-11-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 AUP74_RS08195 2bfc146dae06115aa9c2a87c35eec208 917 SUPERFAMILY SSF46955 3 51 3.66E-8 T 11-11-2016 IPR009061 Putative DNA-binding domain AUP74_RS08195 2bfc146dae06115aa9c2a87c35eec208 917 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 341 391 2.3E-17 T 11-11-2016 IPR006847 Translation initiation factor IF-2, N-terminal AUP74_RS08195 2bfc146dae06115aa9c2a87c35eec208 917 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 47 1.2E-6 T 11-11-2016 IPR006847 Translation initiation factor IF-2, N-terminal AUP74_RS08195 2bfc146dae06115aa9c2a87c35eec208 917 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 420 576 3.1E-32 T 11-11-2016 IPR005225 Small GTP-binding protein domain GO:0005525 AUP74_RS08195 2bfc146dae06115aa9c2a87c35eec208 917 Gene3D G3DSA:2.40.30.10 819 915 2.3E-38 T 11-11-2016 AUP74_RS08195 2bfc146dae06115aa9c2a87c35eec208 917 ProSitePatterns PS01176 Initiation factor 2 signature. 868 890 - T 11-11-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 AUP74_RS08195 2bfc146dae06115aa9c2a87c35eec208 917 SUPERFAMILY SSF50447 819 915 6.48E-33 T 11-11-2016 IPR009000 Translation protein, beta-barrel domain AUP74_RS08195 2bfc146dae06115aa9c2a87c35eec208 917 Gene3D G3DSA:3.30.56.50 2 51 1.6E-17 T 11-11-2016 AUP74_RS08195 2bfc146dae06115aa9c2a87c35eec208 917 Gene3D G3DSA:2.40.30.10 591 681 7.3E-23 T 11-11-2016 AUP74_RS08195 2bfc146dae06115aa9c2a87c35eec208 917 SUPERFAMILY SSF52156 695 824 4.45E-36 T 11-11-2016 IPR023115 Translation initiation factor IF- 2, domain 3 AUP74_RS08195 2bfc146dae06115aa9c2a87c35eec208 917 Pfam PF11987 Translation-initiation factor 2 702 807 4.8E-35 T 11-11-2016 IPR023115 Translation initiation factor IF- 2, domain 3 AUP74_RS08195 2bfc146dae06115aa9c2a87c35eec208 917 SUPERFAMILY SSF52540 404 586 6.96E-51 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11790 1a5c5a075044050ff911e9143aff0a04 83 Gene3D G3DSA:1.10.10.620 1 64 3.4E-24 T 11-11-2016 IPR023200 Ribosome modulation factor-like domain AUP74_RS11790 1a5c5a075044050ff911e9143aff0a04 83 Pfam PF04957 Ribosome modulation factor 1 54 1.3E-22 T 11-11-2016 IPR007040 Ribosome modulation factor AUP74_RS11790 1a5c5a075044050ff911e9143aff0a04 83 ProDom PD051650 RIBOSOME MODULATION FACTOR E FACTOR-RELATED DIMERIZATION BIOGENESIS RIBOSOMES INVOLVED 70S 1 50 5.0E-10 T 11-11-2016 IPR007040 Ribosome modulation factor AUP74_RS11805 86194383518ce68785ac7335ff45a032 813 Gene3D G3DSA:1.10.510.10 124 271 1.3E-40 T 11-11-2016 AUP74_RS11805 86194383518ce68785ac7335ff45a032 813 Pfam PF08308 PEGA domain 502 564 1.1E-4 T 11-11-2016 IPR013229 PEGA AUP74_RS11805 86194383518ce68785ac7335ff45a032 813 Gene3D G3DSA:2.60.40.1120 524 563 1.6E-4 T 11-11-2016 IPR014766 Carboxypeptidase, regulatory domain AUP74_RS11805 86194383518ce68785ac7335ff45a032 813 Pfam PF03781 Sulfatase-modifying factor enzyme 1 582 809 9.2E-52 T 11-11-2016 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 AUP74_RS11805 86194383518ce68785ac7335ff45a032 813 SUPERFAMILY SSF56112 14 270 1.35E-75 T 11-11-2016 IPR011009 Protein kinase-like domain AUP74_RS11805 86194383518ce68785ac7335ff45a032 813 Pfam PF00069 Protein kinase domain 16 258 6.4E-50 T 11-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AUP74_RS11805 86194383518ce68785ac7335ff45a032 813 SMART SM00220 16 272 2.8E-66 T 11-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AUP74_RS11805 86194383518ce68785ac7335ff45a032 813 Gene3D G3DSA:3.30.200.20 12 123 6.1E-31 T 11-11-2016 AUP74_RS11805 86194383518ce68785ac7335ff45a032 813 Gene3D G3DSA:3.90.1580.10 578 812 3.6E-64 T 11-11-2016 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 AUP74_RS11805 86194383518ce68785ac7335ff45a032 813 SUPERFAMILY SSF56436 582 811 2.35E-60 T 11-11-2016 IPR016187 C-type lectin fold AUP74_RS11805 86194383518ce68785ac7335ff45a032 813 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 11-11-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AUP74_RS06270 75b0f38de187ad9a4cf731fdd6776074 74 SMART SM00530 11 66 2.5E-16 T 11-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AUP74_RS06270 75b0f38de187ad9a4cf731fdd6776074 74 SUPERFAMILY SSF47413 10 72 4.29E-17 T 11-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AUP74_RS06270 75b0f38de187ad9a4cf731fdd6776074 74 Pfam PF01381 Helix-turn-helix 12 66 1.9E-17 T 11-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AUP74_RS06270 75b0f38de187ad9a4cf731fdd6776074 74 Gene3D G3DSA:1.10.260.40 10 71 1.5E-19 T 11-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AUP74_RS01990 223f11494e823392c3e55d9e40b88d14 632 SUPERFAMILY SSF51011 546 631 9.16E-7 T 11-11-2016 AUP74_RS01990 223f11494e823392c3e55d9e40b88d14 632 Pfam PF00128 Alpha amylase, catalytic domain 86 462 3.2E-18 T 11-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AUP74_RS01990 223f11494e823392c3e55d9e40b88d14 632 SUPERFAMILY SSF51445 45 528 3.63E-86 T 11-11-2016 IPR017853 Glycoside hydrolase superfamily AUP74_RS01990 223f11494e823392c3e55d9e40b88d14 632 Gene3D G3DSA:3.20.20.80 45 521 6.1E-83 T 11-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 AUP74_RS01990 223f11494e823392c3e55d9e40b88d14 632 SMART SM00642 51 521 1.2E-7 T 11-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AUP74_RS01990 223f11494e823392c3e55d9e40b88d14 632 Gene3D G3DSA:2.60.40.1180 548 630 8.9E-11 T 11-11-2016 IPR013780 Glycosyl hydrolase, all-beta AUP74_RS16720 8ac6172f2b14fa0d3ed67ac972436a38 411 SMART SM00842 10 196 1.2E-109 T 11-11-2016 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 AUP74_RS16720 8ac6172f2b14fa0d3ed67ac972436a38 411 SUPERFAMILY SSF53067 9 197 6.26E-65 T 11-11-2016 AUP74_RS16720 8ac6172f2b14fa0d3ed67ac972436a38 411 Gene3D G3DSA:3.30.1490.110 98 157 5.6E-19 T 11-11-2016 AUP74_RS16720 8ac6172f2b14fa0d3ed67ac972436a38 411 Pfam PF14450 Cell division protein FtsA 11 193 3.1E-12 T 11-11-2016 AUP74_RS16720 8ac6172f2b14fa0d3ed67ac972436a38 411 Pfam PF14450 Cell division protein FtsA 207 374 3.9E-25 T 11-11-2016 AUP74_RS16720 8ac6172f2b14fa0d3ed67ac972436a38 411 Gene3D G3DSA:3.30.420.40 298 351 2.7E-34 T 11-11-2016 AUP74_RS16720 8ac6172f2b14fa0d3ed67ac972436a38 411 Gene3D G3DSA:3.30.420.40 210 234 2.7E-34 T 11-11-2016 AUP74_RS16720 8ac6172f2b14fa0d3ed67ac972436a38 411 Gene3D G3DSA:3.30.420.40 158 209 2.8E-26 T 11-11-2016 AUP74_RS16720 8ac6172f2b14fa0d3ed67ac972436a38 411 Gene3D G3DSA:3.30.420.40 3 83 2.8E-26 T 11-11-2016 AUP74_RS16720 8ac6172f2b14fa0d3ed67ac972436a38 411 Pfam PF02491 SHS2 domain inserted in FTSA 85 161 8.2E-34 T 11-11-2016 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 AUP74_RS16720 8ac6172f2b14fa0d3ed67ac972436a38 411 SUPERFAMILY SSF53067 198 378 3.62E-50 T 11-11-2016 AUP74_RS16720 8ac6172f2b14fa0d3ed67ac972436a38 411 Hamap MF_02033 Cell division protein FtsA [ftsA]. 6 411 31.827 T 11-11-2016 IPR020823 Cell division protein FtsA GO:0007049 AUP74_RS16720 8ac6172f2b14fa0d3ed67ac972436a38 411 PIRSF PIRSF003101 1 411 9.2E-162 T 11-11-2016 IPR020823 Cell division protein FtsA GO:0007049 AUP74_RS16720 8ac6172f2b14fa0d3ed67ac972436a38 411 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 9 378 6.3E-159 T 11-11-2016 IPR020823 Cell division protein FtsA GO:0007049 AUP74_RS16720 8ac6172f2b14fa0d3ed67ac972436a38 411 Gene3D G3DSA:3.90.640.10 235 297 5.7E-20 T 11-11-2016 AUP74_RS15905 966e7e025d8a7f962db08b7a8225482a 212 SUPERFAMILY SSF88659 135 199 1.01E-11 T 11-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS15905 966e7e025d8a7f962db08b7a8225482a 212 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 26 198 2.1E-25 T 11-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS15905 966e7e025d8a7f962db08b7a8225482a 212 SUPERFAMILY SSF88946 25 106 1.02E-18 T 11-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS15905 966e7e025d8a7f962db08b7a8225482a 212 Gene3D G3DSA:1.10.10.10 135 200 8.1E-12 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS15905 966e7e025d8a7f962db08b7a8225482a 212 Gene3D G3DSA:1.10.1740.10 26 108 2.1E-19 T 11-11-2016 AUP74_RS15905 966e7e025d8a7f962db08b7a8225482a 212 Pfam PF04542 Sigma-70 region 2 24 92 2.4E-15 T 11-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS15905 966e7e025d8a7f962db08b7a8225482a 212 TIGRFAM TIGR02943 Sig70_famx1: RNA polymerase sigma-70 factor, TIGR02943 family 21 205 3.9E-75 T 11-11-2016 IPR014289 RNA polymerase sigma-24-related AUP74_RS15905 966e7e025d8a7f962db08b7a8225482a 212 Pfam PF08281 Sigma-70, region 4 144 194 1.3E-8 T 11-11-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS11590 41eeca572ce277f5fdbd8be4e79a1571 458 Gene3D G3DSA:1.20.120.640 307 390 5.4E-15 T 11-11-2016 AUP74_RS11590 41eeca572ce277f5fdbd8be4e79a1571 458 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 2.1E-28 T 11-11-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 AUP74_RS11590 41eeca572ce277f5fdbd8be4e79a1571 458 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 2.1E-28 T 11-11-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 AUP74_RS11590 41eeca572ce277f5fdbd8be4e79a1571 458 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 2.1E-28 T 11-11-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 AUP74_RS11590 41eeca572ce277f5fdbd8be4e79a1571 458 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 2.1E-28 T 11-11-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 AUP74_RS11590 41eeca572ce277f5fdbd8be4e79a1571 458 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 457 1.6E-159 T 11-11-2016 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 AUP74_RS11590 41eeca572ce277f5fdbd8be4e79a1571 458 Pfam PF09190 DALR domain 341 398 1.8E-16 T 11-11-2016 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 AUP74_RS11590 41eeca572ce277f5fdbd8be4e79a1571 458 Gene3D G3DSA:3.40.50.620 21 305 3.4E-102 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS11590 41eeca572ce277f5fdbd8be4e79a1571 458 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 458 38.074 T 11-11-2016 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 AUP74_RS11590 41eeca572ce277f5fdbd8be4e79a1571 458 SMART SM00840 340 398 1.8E-19 T 11-11-2016 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 AUP74_RS11590 41eeca572ce277f5fdbd8be4e79a1571 458 SUPERFAMILY SSF47323 316 457 4.18E-33 T 11-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS11590 41eeca572ce277f5fdbd8be4e79a1571 458 SUPERFAMILY SSF52374 4 314 4.16E-93 T 11-11-2016 AUP74_RS11590 41eeca572ce277f5fdbd8be4e79a1571 458 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 312 3.0E-123 T 11-11-2016 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 AUP74_RS00005 abaf54ea9f4049c09fdf8db035654b44 188 TIGRFAM TIGR04409 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC 3 185 9.9E-32 T 11-11-2016 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 AUP74_RS00005 abaf54ea9f4049c09fdf8db035654b44 188 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 8 186 3.6E-33 T 11-11-2016 IPR010664 Lipopolysaccharide assembly, LptC-related AUP74_RS00005 abaf54ea9f4049c09fdf8db035654b44 188 Hamap MF_01915 Lipopolysaccharide export system protein LptC [lptC]. 1 188 19.773 T 11-11-2016 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 AUP74_RS07750 8737628d4a4cc926ba47ff293f65f18c 296 Gene3D G3DSA:3.30.1600.10 145 218 2.8E-21 T 11-11-2016 IPR026591 Sirtuin family, catalytic core small domain AUP74_RS07750 8737628d4a4cc926ba47ff293f65f18c 296 Gene3D G3DSA:3.30.1600.10 58 93 2.8E-21 T 11-11-2016 IPR026591 Sirtuin family, catalytic core small domain AUP74_RS07750 8737628d4a4cc926ba47ff293f65f18c 296 Hamap MF_01967 NAD-dependent protein deacetylase [cobB]. 23 292 58.819 T 11-11-2016 IPR026587 Sirtuin, class II AUP74_RS07750 8737628d4a4cc926ba47ff293f65f18c 296 SUPERFAMILY SSF52467 29 292 2.91E-81 T 11-11-2016 IPR029035 DHS-like NAD/FAD-binding domain AUP74_RS07750 8737628d4a4cc926ba47ff293f65f18c 296 Pfam PF02146 Sir2 family 47 248 1.8E-49 T 11-11-2016 IPR003000 Sirtuin family GO:0070403 AUP74_RS07750 8737628d4a4cc926ba47ff293f65f18c 296 Gene3D G3DSA:3.40.50.1220 224 295 3.5E-41 T 11-11-2016 IPR029035 DHS-like NAD/FAD-binding domain AUP74_RS07750 8737628d4a4cc926ba47ff293f65f18c 296 Gene3D G3DSA:3.40.50.1220 28 57 3.5E-41 T 11-11-2016 IPR029035 DHS-like NAD/FAD-binding domain AUP74_RS07750 8737628d4a4cc926ba47ff293f65f18c 296 Gene3D G3DSA:3.40.50.1220 107 144 3.5E-41 T 11-11-2016 IPR029035 DHS-like NAD/FAD-binding domain AUP74_RS03670 bc79022ba94d698239611abbd368a45b 280 SUPERFAMILY SSF82689 168 267 2.62E-28 T 11-11-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 AUP74_RS03670 bc79022ba94d698239611abbd368a45b 280 SUPERFAMILY SSF50182 101 167 1.34E-16 T 11-11-2016 IPR010920 LSM domain AUP74_RS03670 bc79022ba94d698239611abbd368a45b 280 Pfam PF00924 Mechanosensitive ion channel 60 256 1.2E-54 T 11-11-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 AUP74_RS03670 bc79022ba94d698239611abbd368a45b 280 Gene3D G3DSA:3.30.70.100 170 253 3.6E-24 T 11-11-2016 AUP74_RS03670 bc79022ba94d698239611abbd368a45b 280 SUPERFAMILY SSF82861 21 100 1.83E-15 T 11-11-2016 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 AUP74_RS03670 bc79022ba94d698239611abbd368a45b 280 Gene3D G3DSA:2.30.30.60 117 166 1.8E-17 T 11-11-2016 AUP74_RS13640 536694468e8f731c2ade512710210d89 691 SMART SM00028 590 623 6.5 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS13640 536694468e8f731c2ade512710210d89 691 SMART SM00028 556 589 46.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS13640 536694468e8f731c2ade512710210d89 691 SMART SM00028 624 657 130.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS13640 536694468e8f731c2ade512710210d89 691 SMART SM00028 522 555 2.2E-5 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS13640 536694468e8f731c2ade512710210d89 691 Pfam PF13435 Cytochrome c554 and c-prime 114 153 4.0E-4 T 11-11-2016 IPR023155 Cytochrome c-552/4 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 AUP74_RS13640 536694468e8f731c2ade512710210d89 691 Gene3D G3DSA:1.10.710.10 91 222 1.5E-32 T 11-11-2016 IPR023155 Cytochrome c-552/4 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 AUP74_RS13640 536694468e8f731c2ade512710210d89 691 Gene3D G3DSA:1.10.710.10 261 365 1.5E-32 T 11-11-2016 IPR023155 Cytochrome c-552/4 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 AUP74_RS13640 536694468e8f731c2ade512710210d89 691 Gene3D G3DSA:1.25.40.10 502 683 1.4E-31 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS13640 536694468e8f731c2ade512710210d89 691 SUPERFAMILY SSF48452 503 683 3.03E-25 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS13640 536694468e8f731c2ade512710210d89 691 Pfam PF07719 Tetratricopeptide repeat 522 553 4.9E-5 T 11-11-2016 IPR013105 Tetratricopeptide repeat 2 AUP74_RS13640 536694468e8f731c2ade512710210d89 691 Pfam PF13429 Tetratricopeptide repeat 560 684 9.9E-9 T 11-11-2016 AUP74_RS13640 536694468e8f731c2ade512710210d89 691 SUPERFAMILY SSF48695 28 218 3.69E-60 T 11-11-2016 IPR011031 Multihaem cytochrome AUP74_RS13640 536694468e8f731c2ade512710210d89 691 SUPERFAMILY SSF48695 251 381 3.69E-60 T 11-11-2016 IPR011031 Multihaem cytochrome AUP74_RS12590 65444e578e74f748a3be1a9a7d451cb1 346 SUPERFAMILY SSF55326 15 162 2.79E-35 T 11-11-2016 AUP74_RS12590 65444e578e74f748a3be1a9a7d451cb1 346 Gene3D G3DSA:3.30.1330.10 38 161 2.3E-26 T 11-11-2016 IPR016188 PurM-like, N-terminal domain AUP74_RS12590 65444e578e74f748a3be1a9a7d451cb1 346 SUPERFAMILY SSF56042 170 342 6.58E-41 T 11-11-2016 IPR010918 AIR synthase-related protein, C-terminal domain AUP74_RS12590 65444e578e74f748a3be1a9a7d451cb1 346 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 15 346 2.2E-136 T 11-11-2016 IPR011854 Hydrogenase expression/formation protein HypE AUP74_RS12590 65444e578e74f748a3be1a9a7d451cb1 346 Pfam PF02769 AIR synthase related protein, C-terminal domain 172 316 5.4E-25 T 11-11-2016 IPR010918 AIR synthase-related protein, C-terminal domain AUP74_RS12590 65444e578e74f748a3be1a9a7d451cb1 346 Gene3D G3DSA:3.90.650.10 172 315 3.6E-23 T 11-11-2016 IPR010918 AIR synthase-related protein, C-terminal domain AUP74_RS12590 65444e578e74f748a3be1a9a7d451cb1 346 PIRSF PIRSF005644 10 346 2.2E-124 T 11-11-2016 IPR011854 Hydrogenase expression/formation protein HypE AUP74_RS12590 65444e578e74f748a3be1a9a7d451cb1 346 Pfam PF00586 AIR synthase related protein, N-terminal domain 48 159 5.3E-18 T 11-11-2016 IPR016188 PurM-like, N-terminal domain AUP74_RS04845 4d7d007f602b66dee43646ee05e9887a 136 SUPERFAMILY SSF55021 69 129 1.5E-18 T 11-11-2016 AUP74_RS04845 4d7d007f602b66dee43646ee05e9887a 136 Gene3D G3DSA:3.30.2130.10 1 130 2.2E-46 T 11-11-2016 AUP74_RS04845 4d7d007f602b66dee43646ee05e9887a 136 Pfam PF13840 ACT domain 71 127 1.4E-10 T 11-11-2016 IPR027795 GATS-like ACT domain AUP74_RS04845 4d7d007f602b66dee43646ee05e9887a 136 SUPERFAMILY SSF55021 3 65 4.3E-13 T 11-11-2016 AUP74_RS04845 4d7d007f602b66dee43646ee05e9887a 136 Pfam PF10000 ACT domain 3 68 1.1E-15 T 11-11-2016 IPR018717 Domain of unknown function DUF2241 AUP74_RS07080 5ed560f39ed01ac69502ead4ff9b645a 934 Gene3D G3DSA:3.40.50.620 405 632 9.9E-137 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS07080 5ed560f39ed01ac69502ead4ff9b645a 934 Gene3D G3DSA:3.40.50.620 17 205 9.9E-137 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS07080 5ed560f39ed01ac69502ead4ff9b645a 934 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 2 925 21.213 T 11-11-2016 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 AUP74_RS07080 5ed560f39ed01ac69502ead4ff9b645a 934 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 15 841 2.2E-285 T 11-11-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AUP74_RS07080 5ed560f39ed01ac69502ead4ff9b645a 934 SUPERFAMILY SSF50677 204 403 8.24E-55 T 11-11-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AUP74_RS07080 5ed560f39ed01ac69502ead4ff9b645a 934 SUPERFAMILY SSF47323 651 925 6.35E-75 T 11-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS07080 5ed560f39ed01ac69502ead4ff9b645a 934 Gene3D G3DSA:1.10.730.10 641 788 3.0E-43 T 11-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS07080 5ed560f39ed01ac69502ead4ff9b645a 934 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 58 69 - T 11-11-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS07080 5ed560f39ed01ac69502ead4ff9b645a 934 Pfam PF06827 Zinc finger found in FPG and IleRS 896 922 4.4E-6 T 11-11-2016 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 AUP74_RS07080 5ed560f39ed01ac69502ead4ff9b645a 934 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 240 263 1.8E-32 T 11-11-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AUP74_RS07080 5ed560f39ed01ac69502ead4ff9b645a 934 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 401 416 1.8E-32 T 11-11-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AUP74_RS07080 5ed560f39ed01ac69502ead4ff9b645a 934 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 526 539 1.8E-32 T 11-11-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AUP74_RS07080 5ed560f39ed01ac69502ead4ff9b645a 934 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 560 569 1.8E-32 T 11-11-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AUP74_RS07080 5ed560f39ed01ac69502ead4ff9b645a 934 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 51 62 1.8E-32 T 11-11-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AUP74_RS07080 5ed560f39ed01ac69502ead4ff9b645a 934 SUPERFAMILY SSF52374 403 647 4.22E-137 T 11-11-2016 AUP74_RS07080 5ed560f39ed01ac69502ead4ff9b645a 934 SUPERFAMILY SSF52374 3 202 4.22E-137 T 11-11-2016 AUP74_RS07080 5ed560f39ed01ac69502ead4ff9b645a 934 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 28 640 1.5E-224 T 11-11-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS07080 5ed560f39ed01ac69502ead4ff9b645a 934 Gene3D G3DSA:3.90.740.10 241 404 5.3E-58 T 11-11-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AUP74_RS07080 5ed560f39ed01ac69502ead4ff9b645a 934 Pfam PF08264 Anticodon-binding domain of tRNA 684 838 4.9E-26 T 11-11-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 AUP74_RS02440 d3ae5ef182caeb0a86744566a7167cc2 399 SUPERFAMILY SSF51905 270 389 6.39E-43 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS02440 d3ae5ef182caeb0a86744566a7167cc2 399 SUPERFAMILY SSF51905 1 176 6.39E-43 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS02440 d3ae5ef182caeb0a86744566a7167cc2 399 Gene3D G3DSA:3.50.50.60 281 318 1.7E-28 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS02440 d3ae5ef182caeb0a86744566a7167cc2 399 Gene3D G3DSA:3.50.50.60 1 179 1.7E-28 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS02440 d3ae5ef182caeb0a86744566a7167cc2 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 314 1.7E-5 T 11-11-2016 AUP74_RS02440 d3ae5ef182caeb0a86744566a7167cc2 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 155 170 1.7E-5 T 11-11-2016 AUP74_RS02440 d3ae5ef182caeb0a86744566a7167cc2 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 298 1.7E-5 T 11-11-2016 AUP74_RS02440 d3ae5ef182caeb0a86744566a7167cc2 399 Pfam PF01494 FAD binding domain 37 351 2.6E-23 T 11-11-2016 IPR002938 FAD-binding domain GO:0071949 AUP74_RS02440 d3ae5ef182caeb0a86744566a7167cc2 399 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 1 396 2.0E-95 T 11-11-2016 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 AUP74_RS06940 9859be6b900fe6ed250a5ba89fed1636 129 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 129 33.043 T 11-11-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 AUP74_RS06940 9859be6b900fe6ed250a5ba89fed1636 129 PIRSF PIRSF002131 1 129 3.7E-53 T 11-11-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 AUP74_RS06940 9859be6b900fe6ed250a5ba89fed1636 129 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 10 126 6.9E-57 T 11-11-2016 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS06940 9859be6b900fe6ed250a5ba89fed1636 129 SUPERFAMILY SSF53137 15 129 4.58E-48 T 11-11-2016 AUP74_RS06940 9859be6b900fe6ed250a5ba89fed1636 129 Pfam PF00411 Ribosomal protein S11 19 128 8.5E-52 T 11-11-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 AUP74_RS06940 9859be6b900fe6ed250a5ba89fed1636 129 Gene3D G3DSA:3.30.420.80 7 129 1.8E-55 T 11-11-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 AUP74_RS15690 6e1c1eac6a5cb883b814a96a2a7bb4e1 377 SUPERFAMILY SSF53187 294 373 1.13E-64 T 11-11-2016 AUP74_RS15690 6e1c1eac6a5cb883b814a96a2a7bb4e1 377 SUPERFAMILY SSF53187 4 180 1.13E-64 T 11-11-2016 AUP74_RS15690 6e1c1eac6a5cb883b814a96a2a7bb4e1 377 SUPERFAMILY SSF55031 181 290 3.89E-30 T 11-11-2016 IPR011650 Peptidase M20, dimerisation domain AUP74_RS15690 6e1c1eac6a5cb883b814a96a2a7bb4e1 377 Pfam PF07687 Peptidase dimerisation domain 177 283 1.3E-25 T 11-11-2016 IPR011650 Peptidase M20, dimerisation domain AUP74_RS15690 6e1c1eac6a5cb883b814a96a2a7bb4e1 377 Pfam PF01546 Peptidase family M20/M25/M40 64 372 4.9E-44 T 11-11-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 AUP74_RS15690 6e1c1eac6a5cb883b814a96a2a7bb4e1 377 Gene3D G3DSA:3.40.630.10 318 373 5.6E-70 T 11-11-2016 AUP74_RS15690 6e1c1eac6a5cb883b814a96a2a7bb4e1 377 Gene3D G3DSA:3.40.630.10 5 189 5.6E-70 T 11-11-2016 AUP74_RS15690 6e1c1eac6a5cb883b814a96a2a7bb4e1 377 Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. 2 377 51.408 T 11-11-2016 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 AUP74_RS15690 6e1c1eac6a5cb883b814a96a2a7bb4e1 377 TIGRFAM TIGR01246 dapE_proteo: succinyl-diaminopimelate desuccinylase 6 373 8.1E-163 T 11-11-2016 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 AUP74_RS15690 6e1c1eac6a5cb883b814a96a2a7bb4e1 377 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 99 137 - T 11-11-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 AUP74_RS15690 6e1c1eac6a5cb883b814a96a2a7bb4e1 377 Gene3D G3DSA:3.30.70.360 190 290 3.2E-34 T 11-11-2016 IPR011650 Peptidase M20, dimerisation domain AUP74_RS04560 54810b79507b7fcf16ab82c30a2adf1a 438 Pfam PF01029 NusB family 9 127 1.0E-17 T 11-11-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 AUP74_RS04560 54810b79507b7fcf16ab82c30a2adf1a 438 Gene3D G3DSA:3.40.50.150 233 438 6.8E-54 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS04560 54810b79507b7fcf16ab82c30a2adf1a 438 Gene3D G3DSA:3.30.70.1170 174 231 6.8E-24 T 11-11-2016 AUP74_RS04560 54810b79507b7fcf16ab82c30a2adf1a 438 Pfam PF01189 16S rRNA methyltransferase RsmB/F 241 436 1.8E-64 T 11-11-2016 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AUP74_RS04560 54810b79507b7fcf16ab82c30a2adf1a 438 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 317 328 - T 11-11-2016 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AUP74_RS04560 54810b79507b7fcf16ab82c30a2adf1a 438 SUPERFAMILY SSF53335 146 437 5.73E-70 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS04560 54810b79507b7fcf16ab82c30a2adf1a 438 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 10 437 4.5E-123 T 11-11-2016 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AUP74_RS04560 54810b79507b7fcf16ab82c30a2adf1a 438 SUPERFAMILY SSF48013 8 150 4.45E-28 T 11-11-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 AUP74_RS04560 54810b79507b7fcf16ab82c30a2adf1a 438 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 252 262 6.5E-31 T 11-11-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AUP74_RS04560 54810b79507b7fcf16ab82c30a2adf1a 438 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 420 437 6.5E-31 T 11-11-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AUP74_RS04560 54810b79507b7fcf16ab82c30a2adf1a 438 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 318 330 6.5E-31 T 11-11-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AUP74_RS04560 54810b79507b7fcf16ab82c30a2adf1a 438 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 223 237 6.5E-31 T 11-11-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AUP74_RS04560 54810b79507b7fcf16ab82c30a2adf1a 438 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 368 384 6.5E-31 T 11-11-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AUP74_RS04560 54810b79507b7fcf16ab82c30a2adf1a 438 Gene3D G3DSA:1.10.940.10 5 150 4.1E-34 T 11-11-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 AUP74_RS01705 c7952bda09edfc47f934a0190bea63b8 257 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 10 231 1.7E-96 T 11-11-2016 IPR022488 Polyphosphate kinase-2-related AUP74_RS01705 c7952bda09edfc47f934a0190bea63b8 257 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 9 232 6.5E-106 T 11-11-2016 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 AUP74_RS01705 c7952bda09edfc47f934a0190bea63b8 257 Gene3D G3DSA:3.40.50.300 5 231 2.1E-96 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS01705 c7952bda09edfc47f934a0190bea63b8 257 PIRSF PIRSF028756 2 249 2.5E-105 T 11-11-2016 IPR016898 Polyphosphate kinase 2 AUP74_RS01705 c7952bda09edfc47f934a0190bea63b8 257 SUPERFAMILY SSF52540 37 224 3.6E-26 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS16680 8f5640eac0768c66d2dd03b069208017 203 SUPERFAMILY SSF52540 2 193 1.9E-38 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS16680 8f5640eac0768c66d2dd03b069208017 203 Gene3D G3DSA:3.40.50.300 4 199 2.4E-69 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS16680 8f5640eac0768c66d2dd03b069208017 203 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 4 198 27.705 T 11-11-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 AUP74_RS16680 8f5640eac0768c66d2dd03b069208017 203 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 6 189 3.7E-55 T 11-11-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 AUP74_RS16680 8f5640eac0768c66d2dd03b069208017 203 Pfam PF01121 Dephospho-CoA kinase 5 181 1.4E-65 T 11-11-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 AUP74_RS05355 d4e3e88ef5cc4d0266b81f67075cb804 677 Pfam PF00580 UvrD/REP helicase N-terminal domain 4 272 3.0E-74 T 11-11-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 AUP74_RS05355 d4e3e88ef5cc4d0266b81f67075cb804 677 Gene3D G3DSA:1.10.486.10 390 530 7.6E-37 T 11-11-2016 AUP74_RS05355 d4e3e88ef5cc4d0266b81f67075cb804 677 TIGRFAM TIGR01074 rep: ATP-dependent DNA helicase Rep 3 675 4.5E-303 T 11-11-2016 IPR005752 ATP-dependent DNA helicase Rep GO:0003677|GO:0004003|GO:0005524|GO:0006268 AUP74_RS05355 d4e3e88ef5cc4d0266b81f67075cb804 677 Gene3D G3DSA:3.40.50.300 189 286 2.3E-64 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05355 d4e3e88ef5cc4d0266b81f67075cb804 677 Gene3D G3DSA:3.40.50.300 2 111 2.3E-64 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05355 d4e3e88ef5cc4d0266b81f67075cb804 677 Gene3D G3DSA:1.10.10.160 115 188 4.1E-20 T 11-11-2016 IPR013986 DExx box DNA helicase domain AUP74_RS05355 d4e3e88ef5cc4d0266b81f67075cb804 677 Hamap MF_01920 ATP-dependent DNA helicase Rep [rep]. 2 677 39.058 T 11-11-2016 IPR005752 ATP-dependent DNA helicase Rep GO:0003677|GO:0004003|GO:0005524|GO:0006268 AUP74_RS05355 d4e3e88ef5cc4d0266b81f67075cb804 677 Pfam PF13361 UvrD-like helicase C-terminal domain 278 622 4.7E-68 T 11-11-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 AUP74_RS05355 d4e3e88ef5cc4d0266b81f67075cb804 677 Gene3D G3DSA:3.40.50.300 287 389 9.0E-66 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05355 d4e3e88ef5cc4d0266b81f67075cb804 677 Gene3D G3DSA:3.40.50.300 560 647 9.0E-66 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05355 d4e3e88ef5cc4d0266b81f67075cb804 677 SUPERFAMILY SSF52540 2 646 1.41E-164 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11685 1674f0bf35d02481a08e2f95bf124dc4 326 SUPERFAMILY SSF50129 14 150 8.99E-30 T 11-11-2016 IPR011032 GroES-like AUP74_RS11685 1674f0bf35d02481a08e2f95bf124dc4 326 Gene3D G3DSA:3.40.50.720 124 293 4.1E-51 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS11685 1674f0bf35d02481a08e2f95bf124dc4 326 SMART SM00829 10 324 9.2E-10 T 11-11-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AUP74_RS11685 1674f0bf35d02481a08e2f95bf124dc4 326 Gene3D G3DSA:3.90.180.10 17 95 4.9E-15 T 11-11-2016 IPR011032 GroES-like AUP74_RS11685 1674f0bf35d02481a08e2f95bf124dc4 326 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 91 5.7E-9 T 11-11-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AUP74_RS11685 1674f0bf35d02481a08e2f95bf124dc4 326 SUPERFAMILY SSF51735 116 292 2.71E-50 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS11685 1674f0bf35d02481a08e2f95bf124dc4 326 Pfam PF00107 Zinc-binding dehydrogenase 153 267 9.2E-18 T 11-11-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AUP74_RS06800 e7eef7533f3fac784e06cf4cb62ef316 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 155 8.0E-69 T 11-11-2016 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 AUP74_RS06800 e7eef7533f3fac784e06cf4cb62ef316 156 PIRSF PIRSF002122 3 156 8.2E-61 T 11-11-2016 IPR000235 Ribosomal protein S5/S7 GO:0006412 AUP74_RS06800 e7eef7533f3fac784e06cf4cb62ef316 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 3.5E-67 T 11-11-2016 IPR023798 Ribosomal protein S7 domain AUP74_RS06800 e7eef7533f3fac784e06cf4cb62ef316 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 36.309 T 11-11-2016 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 AUP74_RS06800 e7eef7533f3fac784e06cf4cb62ef316 156 SUPERFAMILY SSF47973 6 149 1.09E-62 T 11-11-2016 IPR023798 Ribosomal protein S7 domain AUP74_RS06800 e7eef7533f3fac784e06cf4cb62ef316 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 11-11-2016 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06800 e7eef7533f3fac784e06cf4cb62ef316 156 Gene3D G3DSA:1.10.455.10 8 156 4.4E-66 T 11-11-2016 IPR023798 Ribosomal protein S7 domain AUP74_RS10245 a6871e0750f4450a934d433d53569918 492 PIRSF PIRSF000538 1 492 2.6E-159 T 11-11-2016 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 AUP74_RS10245 a6871e0750f4450a934d433d53569918 492 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 258 446 3.4E-53 T 11-11-2016 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 AUP74_RS10245 a6871e0750f4450a934d433d53569918 492 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 1 488 6.4E-194 T 11-11-2016 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 AUP74_RS10245 a6871e0750f4450a934d433d53569918 492 Gene3D G3DSA:3.30.420.40 250 490 4.7E-87 T 11-11-2016 AUP74_RS10245 a6871e0750f4450a934d433d53569918 492 SUPERFAMILY SSF53067 250 488 3.37E-73 T 11-11-2016 AUP74_RS10245 a6871e0750f4450a934d433d53569918 492 SUPERFAMILY SSF53067 2 251 6.31E-87 T 11-11-2016 AUP74_RS10245 a6871e0750f4450a934d433d53569918 492 Gene3D G3DSA:3.30.420.40 1 249 3.1E-94 T 11-11-2016 AUP74_RS10245 a6871e0750f4450a934d433d53569918 492 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 1 248 6.4E-73 T 11-11-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 AUP74_RS10245 a6871e0750f4450a934d433d53569918 492 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 358 378 - T 11-11-2016 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 AUP74_RS04810 6f9dc753231500d1938cc01bf58555f6 604 PRINTS PR01183 Ribonucleotide reductase large chain signature 363 385 4.4E-29 T 11-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AUP74_RS04810 6f9dc753231500d1938cc01bf58555f6 604 PRINTS PR01183 Ribonucleotide reductase large chain signature 325 348 4.4E-29 T 11-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AUP74_RS04810 6f9dc753231500d1938cc01bf58555f6 604 PRINTS PR01183 Ribonucleotide reductase large chain signature 446 473 4.4E-29 T 11-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AUP74_RS04810 6f9dc753231500d1938cc01bf58555f6 604 PRINTS PR01183 Ribonucleotide reductase large chain signature 287 298 4.4E-29 T 11-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AUP74_RS04810 6f9dc753231500d1938cc01bf58555f6 604 PRINTS PR01183 Ribonucleotide reductase large chain signature 160 179 4.4E-29 T 11-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AUP74_RS04810 6f9dc753231500d1938cc01bf58555f6 604 PRINTS PR01183 Ribonucleotide reductase large chain signature 391 414 4.4E-29 T 11-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AUP74_RS04810 6f9dc753231500d1938cc01bf58555f6 604 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 12 586 6.0E-169 T 11-11-2016 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AUP74_RS04810 6f9dc753231500d1938cc01bf58555f6 604 Gene3D G3DSA:3.20.70.20 253 411 1.6E-131 T 11-11-2016 AUP74_RS04810 6f9dc753231500d1938cc01bf58555f6 604 Gene3D G3DSA:3.20.70.20 4 202 1.6E-131 T 11-11-2016 AUP74_RS04810 6f9dc753231500d1938cc01bf58555f6 604 Gene3D G3DSA:3.20.70.20 539 582 1.6E-131 T 11-11-2016 AUP74_RS04810 6f9dc753231500d1938cc01bf58555f6 604 Gene3D G3DSA:3.20.70.20 446 492 1.6E-131 T 11-11-2016 AUP74_RS04810 6f9dc753231500d1938cc01bf58555f6 604 Pfam PF02867 Ribonucleotide reductase, barrel domain 85 580 6.1E-133 T 11-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AUP74_RS04810 6f9dc753231500d1938cc01bf58555f6 604 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 9 79 1.1E-8 T 11-11-2016 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AUP74_RS04810 6f9dc753231500d1938cc01bf58555f6 604 SUPERFAMILY SSF51998 3 202 9.16E-151 T 11-11-2016 AUP74_RS04810 6f9dc753231500d1938cc01bf58555f6 604 SUPERFAMILY SSF51998 446 594 9.16E-151 T 11-11-2016 AUP74_RS04810 6f9dc753231500d1938cc01bf58555f6 604 SUPERFAMILY SSF51998 253 411 9.16E-151 T 11-11-2016 AUP74_RS06005 8bfd29eb16081f93e33f9076069036df 117 Pfam PF05899 Protein of unknown function (DUF861) 41 112 1.1E-18 T 11-11-2016 IPR008579 Domain of unknown function DUF861, cupin-3 KEGG: 00230+3.5.3.26|MetaCyc: PWY-5692|MetaCyc: PWY-5698 AUP74_RS06005 8bfd29eb16081f93e33f9076069036df 117 Gene3D G3DSA:2.60.120.10 18 116 4.5E-32 T 11-11-2016 IPR014710 RmlC-like jelly roll fold AUP74_RS06005 8bfd29eb16081f93e33f9076069036df 117 SUPERFAMILY SSF51182 22 115 4.78E-20 T 11-11-2016 IPR011051 RmlC-like cupin domain AUP74_RS13440 f7fa43e386ad25180b72b0680e0acc7d 250 SUPERFAMILY SSF53335 2 247 5.36E-62 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS13440 f7fa43e386ad25180b72b0680e0acc7d 250 Pfam PF04445 Putative SAM-dependent methyltransferase 25 247 1.4E-81 T 11-11-2016 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 AUP74_RS13440 f7fa43e386ad25180b72b0680e0acc7d 250 Gene3D G3DSA:3.40.50.150 52 248 4.4E-66 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS13440 f7fa43e386ad25180b72b0680e0acc7d 250 Hamap MF_01523 Ribosomal RNA small subunit methyltransferase J [rsmJ]. 11 249 36.361 T 11-11-2016 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 AUP74_RS12305 94aa43a72b3c4cafdd3f1eed09c3490d 249 SMART SM00893 23 211 5.5E-72 T 11-11-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 AUP74_RS12305 94aa43a72b3c4cafdd3f1eed09c3490d 249 PIRSF PIRSF000090 1 249 3.0E-86 T 11-11-2016 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105 AUP74_RS12305 94aa43a72b3c4cafdd3f1eed09c3490d 249 Gene3D G3DSA:3.40.50.620 1 247 5.0E-106 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS12305 94aa43a72b3c4cafdd3f1eed09c3490d 249 SUPERFAMILY SSF52402 1 242 3.56E-86 T 11-11-2016 AUP74_RS12305 94aa43a72b3c4cafdd3f1eed09c3490d 249 Pfam PF01012 Electron transfer flavoprotein domain 26 206 1.3E-46 T 11-11-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 AUP74_RS12305 94aa43a72b3c4cafdd3f1eed09c3490d 249 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 11-11-2016 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105 AUP74_RS09815 9e3962d05923834f24c4035208b59a29 224 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 142 165 - T 11-11-2016 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AUP74_RS09815 9e3962d05923834f24c4035208b59a29 224 Gene3D G3DSA:3.40.50.170 10 201 6.4E-72 T 11-11-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AUP74_RS09815 9e3962d05923834f24c4035208b59a29 224 SUPERFAMILY SSF53328 11 205 4.45E-67 T 11-11-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AUP74_RS09815 9e3962d05923834f24c4035208b59a29 224 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 11 200 4.8E-77 T 11-11-2016 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 AUP74_RS09815 9e3962d05923834f24c4035208b59a29 224 Pfam PF00551 Formyl transferase 11 190 3.4E-61 T 11-11-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AUP74_RS09815 9e3962d05923834f24c4035208b59a29 224 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 11 196 31.843 T 11-11-2016 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 AUP74_RS00930 eb1c6a26549ce4efe0265d0c4e62c270 136 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 8 123 8.6E-31 T 11-11-2016 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 AUP74_RS00930 eb1c6a26549ce4efe0265d0c4e62c270 136 Gene3D G3DSA:3.10.129.10 3 133 1.6E-45 T 11-11-2016 IPR029069 HotDog domain AUP74_RS00930 eb1c6a26549ce4efe0265d0c4e62c270 136 SUPERFAMILY SSF54637 3 131 1.28E-38 T 11-11-2016 IPR029069 HotDog domain AUP74_RS00930 eb1c6a26549ce4efe0265d0c4e62c270 136 PIRSF PIRSF003230 1 136 5.5E-43 T 11-11-2016 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 AUP74_RS00930 eb1c6a26549ce4efe0265d0c4e62c270 136 Pfam PF03061 Thioesterase superfamily 19 100 1.3E-14 T 11-11-2016 IPR006683 Thioesterase domain Reactome: R-HSA-75105 AUP74_RS16090 425423b8fe373d62e4565047348ebeed 292 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 24 267 34.197 T 11-11-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS16090 425423b8fe373d62e4565047348ebeed 292 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 24 262 3.5E-67 T 11-11-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS16090 425423b8fe373d62e4565047348ebeed 292 SUPERFAMILY SSF55120 23 274 2.16E-87 T 11-11-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS16090 425423b8fe373d62e4565047348ebeed 292 Gene3D G3DSA:3.30.70.580 24 128 3.8E-36 T 11-11-2016 IPR020094 Pseudouridine synthase I, TruA, N-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS16090 425423b8fe373d62e4565047348ebeed 292 Gene3D G3DSA:3.30.70.660 130 266 3.0E-47 T 11-11-2016 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS16090 425423b8fe373d62e4565047348ebeed 292 PIRSF PIRSF001430 23 279 1.6E-75 T 11-11-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS16090 425423b8fe373d62e4565047348ebeed 292 Pfam PF01416 tRNA pseudouridine synthase 170 268 5.3E-32 T 11-11-2016 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS16090 425423b8fe373d62e4565047348ebeed 292 Pfam PF01416 tRNA pseudouridine synthase 31 127 6.3E-10 T 11-11-2016 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS12525 05aa9993f71822bcc591331ccc8cee7c 269 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 22 263 1.9E-29 T 11-11-2016 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 AUP74_RS12525 05aa9993f71822bcc591331ccc8cee7c 269 SUPERFAMILY SSF53213 6 263 2.75E-85 T 11-11-2016 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 AUP74_RS12525 05aa9993f71822bcc591331ccc8cee7c 269 Gene3D G3DSA:3.40.830.10 4 263 1.5E-89 T 11-11-2016 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 AUP74_RS12525 05aa9993f71822bcc591331ccc8cee7c 269 PIRSF PIRSF006157 1 265 4.1E-86 T 11-11-2016 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA type GO:0008270|GO:0016701|GO:0055114 AUP74_RS15785 81fe328fc3d20270b603bb326734a369 255 SMART SM00967 19 97 1.1E-5 T 11-11-2016 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 AUP74_RS15785 81fe328fc3d20270b603bb326734a369 255 Gene3D G3DSA:3.30.1330.30 19 90 1.8E-10 T 11-11-2016 IPR029064 50S ribosomal protein L30e-like AUP74_RS15785 81fe328fc3d20270b603bb326734a369 255 Pfam PF00588 SpoU rRNA Methylase family 113 249 2.1E-32 T 11-11-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 AUP74_RS15785 81fe328fc3d20270b603bb326734a369 255 SUPERFAMILY SSF75217 112 251 7.85E-36 T 11-11-2016 IPR029028 Alpha/beta knot methyltransferases AUP74_RS15785 81fe328fc3d20270b603bb326734a369 255 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 20 96 6.4E-8 T 11-11-2016 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 AUP74_RS15785 81fe328fc3d20270b603bb326734a369 255 SUPERFAMILY SSF55315 15 90 1.18E-7 T 11-11-2016 IPR029064 50S ribosomal protein L30e-like AUP74_RS15785 81fe328fc3d20270b603bb326734a369 255 Gene3D G3DSA:3.40.1280.10 112 251 9.4E-43 T 11-11-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AUP74_RS03875 d09e2dd2139e4e39bf9401d6ae1c1785 163 Gene3D G3DSA:1.20.1550.10 2 162 4.0E-49 T 11-11-2016 IPR023380 Disulphide bond formation protein DsbB-like domain AUP74_RS03875 d09e2dd2139e4e39bf9401d6ae1c1785 163 Hamap MF_00286 Disulfide bond formation protein B [dsbB]. 2 163 23.02 T 11-11-2016 IPR022920 Disulphide bond formation protein DsbB AUP74_RS03875 d09e2dd2139e4e39bf9401d6ae1c1785 163 SUPERFAMILY SSF158442 10 158 8.24E-42 T 11-11-2016 AUP74_RS03875 d09e2dd2139e4e39bf9401d6ae1c1785 163 Pfam PF02600 Disulfide bond formation protein DsbB 7 157 2.1E-40 T 11-11-2016 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 AUP74_RS10165 56d31a33f0ff0189881c25f19d110a7b 410 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 131 233 3.1E-18 T 11-11-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 AUP74_RS10165 56d31a33f0ff0189881c25f19d110a7b 410 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 245 395 1.1E-34 T 11-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AUP74_RS10165 56d31a33f0ff0189881c25f19d110a7b 410 SUPERFAMILY SSF47203 243 398 3.54E-41 T 11-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AUP74_RS10165 56d31a33f0ff0189881c25f19d110a7b 410 Gene3D G3DSA:1.20.140.10 236 398 3.2E-45 T 11-11-2016 AUP74_RS10165 56d31a33f0ff0189881c25f19d110a7b 410 Gene3D G3DSA:2.40.110.10 130 235 1.0E-38 T 11-11-2016 AUP74_RS10165 56d31a33f0ff0189881c25f19d110a7b 410 Gene3D G3DSA:1.10.540.10 2 129 7.7E-36 T 11-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 AUP74_RS10165 56d31a33f0ff0189881c25f19d110a7b 410 SUPERFAMILY SSF56645 2 258 4.71E-67 T 11-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 AUP74_RS10165 56d31a33f0ff0189881c25f19d110a7b 410 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 127 1.8E-15 T 11-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 AUP74_RS12505 5ab2dae0f4cf6cf315d3f68f638fe112 132 Pfam PF07883 Cupin domain 42 105 1.7E-13 T 11-11-2016 IPR013096 Cupin 2, conserved barrel AUP74_RS12505 5ab2dae0f4cf6cf315d3f68f638fe112 132 Gene3D G3DSA:2.60.120.10 8 130 1.2E-36 T 11-11-2016 IPR014710 RmlC-like jelly roll fold AUP74_RS12505 5ab2dae0f4cf6cf315d3f68f638fe112 132 SUPERFAMILY SSF51182 7 130 3.26E-33 T 11-11-2016 IPR011051 RmlC-like cupin domain AUP74_RS03045 fa65cf4e9056bc320b8d3658668f9b00 333 SMART SM00342 247 329 1.5E-25 T 11-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AUP74_RS03045 fa65cf4e9056bc320b8d3658668f9b00 333 Gene3D G3DSA:1.10.10.60 282 331 4.1E-16 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS03045 fa65cf4e9056bc320b8d3658668f9b00 333 SUPERFAMILY SSF46689 283 331 2.2E-13 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS03045 fa65cf4e9056bc320b8d3658668f9b00 333 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 283 325 - T 11-11-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AUP74_RS03045 fa65cf4e9056bc320b8d3658668f9b00 333 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 298 313 3.0E-7 T 11-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AUP74_RS03045 fa65cf4e9056bc320b8d3658668f9b00 333 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 313 329 3.0E-7 T 11-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AUP74_RS03045 fa65cf4e9056bc320b8d3658668f9b00 333 Pfam PF12833 Helix-turn-helix domain 253 331 7.8E-22 T 11-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AUP74_RS03045 fa65cf4e9056bc320b8d3658668f9b00 333 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 33 204 7.0E-31 T 11-11-2016 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal AUP74_RS01685 d0f8cb0d10d7316abdf20be6c7a771c2 258 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AUP74_RS01685 d0f8cb0d10d7316abdf20be6c7a771c2 258 SMART SM00382 34 216 2.3E-13 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS01685 d0f8cb0d10d7316abdf20be6c7a771c2 258 Gene3D G3DSA:3.40.50.300 12 229 3.0E-60 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS01685 d0f8cb0d10d7316abdf20be6c7a771c2 258 Pfam PF00005 ABC transporter 25 169 1.1E-27 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AUP74_RS01685 d0f8cb0d10d7316abdf20be6c7a771c2 258 SUPERFAMILY SSF52540 12 229 4.46E-57 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS16110 713e6c19a646f90847f5b389b960968c 371 TIGRFAM TIGR01745 asd_gamma: aspartate-semialdehyde dehydrogenase 3 368 4.6E-191 T 11-11-2016 IPR011534 Aspartate-semialdehyde dehydrogenase, gamma-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 AUP74_RS16110 713e6c19a646f90847f5b389b960968c 371 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 122 8.0E-23 T 11-11-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 AUP74_RS16110 713e6c19a646f90847f5b389b960968c 371 PIRSF PIRSF000148 1 371 2.9E-66 T 11-11-2016 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 AUP74_RS16110 713e6c19a646f90847f5b389b960968c 371 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 262 276 - T 11-11-2016 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 AUP74_RS16110 713e6c19a646f90847f5b389b960968c 371 SUPERFAMILY SSF51735 1 148 2.15E-50 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS16110 713e6c19a646f90847f5b389b960968c 371 SUPERFAMILY SSF55347 135 355 4.64E-80 T 11-11-2016 AUP74_RS16110 713e6c19a646f90847f5b389b960968c 371 Gene3D G3DSA:3.40.50.720 1 143 6.0E-59 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS16110 713e6c19a646f90847f5b389b960968c 371 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 145 354 7.1E-56 T 11-11-2016 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AUP74_RS16110 713e6c19a646f90847f5b389b960968c 371 Gene3D G3DSA:3.30.360.10 144 351 4.5E-78 T 11-11-2016 AUP74_RS16110 713e6c19a646f90847f5b389b960968c 371 SMART SM00859 3 123 1.5E-25 T 11-11-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 AUP74_RS16110 713e6c19a646f90847f5b389b960968c 371 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 1 368 34.273 T 11-11-2016 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 AUP74_RS06785 4470e9d1cdcbaad5fc8674defd05d230 1357 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 8 1354 0.0 T 11-11-2016 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS06785 4470e9d1cdcbaad5fc8674defd05d230 1357 Pfam PF00562 RNA polymerase Rpb2, domain 6 722 1279 1.4E-158 T 11-11-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS06785 4470e9d1cdcbaad5fc8674defd05d230 1357 Pfam PF04563 RNA polymerase beta subunit 27 504 3.6E-42 T 11-11-2016 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS06785 4470e9d1cdcbaad5fc8674defd05d230 1357 Gene3D G3DSA:2.40.50.100 719 797 1.1E-30 T 11-11-2016 AUP74_RS06785 4470e9d1cdcbaad5fc8674defd05d230 1357 Pfam PF10385 RNA polymerase beta subunit external 1 domain 596 661 2.7E-24 T 11-11-2016 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS06785 4470e9d1cdcbaad5fc8674defd05d230 1357 Gene3D G3DSA:2.30.150.10 597 661 2.3E-27 T 11-11-2016 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS06785 4470e9d1cdcbaad5fc8674defd05d230 1357 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 13 1357 12.353 T 11-11-2016 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS06785 4470e9d1cdcbaad5fc8674defd05d230 1357 Gene3D G3DSA:3.90.1100.10 450 596 4.9E-149 T 11-11-2016 AUP74_RS06785 4470e9d1cdcbaad5fc8674defd05d230 1357 Gene3D G3DSA:3.90.1100.10 664 718 4.9E-149 T 11-11-2016 AUP74_RS06785 4470e9d1cdcbaad5fc8674defd05d230 1357 Gene3D G3DSA:3.90.1100.10 20 155 4.9E-149 T 11-11-2016 AUP74_RS06785 4470e9d1cdcbaad5fc8674defd05d230 1357 SUPERFAMILY SSF64484 1056 1356 0.0 T 11-11-2016 AUP74_RS06785 4470e9d1cdcbaad5fc8674defd05d230 1357 SUPERFAMILY SSF64484 11 230 0.0 T 11-11-2016 AUP74_RS06785 4470e9d1cdcbaad5fc8674defd05d230 1357 SUPERFAMILY SSF64484 348 944 0.0 T 11-11-2016 AUP74_RS06785 4470e9d1cdcbaad5fc8674defd05d230 1357 Gene3D G3DSA:2.40.270.10 798 825 3.1E-87 T 11-11-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS06785 4470e9d1cdcbaad5fc8674defd05d230 1357 Gene3D G3DSA:2.40.270.10 1077 1257 3.1E-87 T 11-11-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS06785 4470e9d1cdcbaad5fc8674defd05d230 1357 Gene3D G3DSA:3.90.1110.10 351 449 2.2E-68 T 11-11-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS06785 4470e9d1cdcbaad5fc8674defd05d230 1357 Gene3D G3DSA:3.90.1110.10 157 234 2.2E-68 T 11-11-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS06785 4470e9d1cdcbaad5fc8674defd05d230 1357 Pfam PF04560 RNA polymerase Rpb2, domain 7 1281 1355 3.4E-26 T 11-11-2016 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS06785 4470e9d1cdcbaad5fc8674defd05d230 1357 Pfam PF04561 RNA polymerase Rpb2, domain 2 156 227 1.9E-7 T 11-11-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS06785 4470e9d1cdcbaad5fc8674defd05d230 1357 Pfam PF04561 RNA polymerase Rpb2, domain 2 353 459 1.5E-17 T 11-11-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS06785 4470e9d1cdcbaad5fc8674defd05d230 1357 Pfam PF04565 RNA polymerase Rpb2, domain 3 518 585 1.6E-30 T 11-11-2016 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS06785 4470e9d1cdcbaad5fc8674defd05d230 1357 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1080 1092 - T 11-11-2016 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS06785 4470e9d1cdcbaad5fc8674defd05d230 1357 Gene3D G3DSA:2.40.50.150 833 942 2.7E-56 T 11-11-2016 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS06785 4470e9d1cdcbaad5fc8674defd05d230 1357 Gene3D G3DSA:2.40.50.150 1062 1076 2.7E-56 T 11-11-2016 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS02450 c51607cc064bb4ef14e74832bf32a4f5 186 Pfam PF03695 Uncharacterised protein family (UPF0149) 12 172 1.1E-29 T 11-11-2016 IPR011978 Uncharacterised protein family UPF0149 AUP74_RS02450 c51607cc064bb4ef14e74832bf32a4f5 186 SUPERFAMILY SSF101327 6 171 8.76E-30 T 11-11-2016 IPR011978 Uncharacterised protein family UPF0149 AUP74_RS00920 85d2d8f8f25ed3223a2b43f44e7b5a77 143 TIGRFAM TIGR02801 tolR: protein TolR 13 139 1.4E-42 T 11-11-2016 IPR014168 Biopolymer transport, TolR GO:0015031|GO:0016021 AUP74_RS00920 85d2d8f8f25ed3223a2b43f44e7b5a77 143 Pfam PF02472 Biopolymer transport protein ExbD/TolR 10 140 1.5E-26 T 11-11-2016 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 AUP74_RS16700 2d7483145be84185166a84812d508472 915 ProSitePatterns PS01312 SecA family signature. 494 509 - T 11-11-2016 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 AUP74_RS16700 2d7483145be84185166a84812d508472 915 SUPERFAMILY SSF52540 411 617 1.0E-58 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS16700 2d7483145be84185166a84812d508472 915 SMART SM00958 228 352 6.2E-72 T 11-11-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 AUP74_RS16700 2d7483145be84185166a84812d508472 915 Pfam PF07516 SecA Wing and Scaffold domain 616 833 3.1E-67 T 11-11-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 AUP74_RS16700 2d7483145be84185166a84812d508472 915 Pfam PF02810 SEC-C motif 889 907 1.7E-10 T 11-11-2016 IPR004027 SEC-C motif AUP74_RS16700 2d7483145be84185166a84812d508472 915 Gene3D G3DSA:3.40.50.300 411 618 3.4E-90 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS16700 2d7483145be84185166a84812d508472 915 SUPERFAMILY SSF81886 885 897 2.75E-81 T 11-11-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 AUP74_RS16700 2d7483145be84185166a84812d508472 915 SUPERFAMILY SSF81886 619 844 2.75E-81 T 11-11-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 AUP74_RS16700 2d7483145be84185166a84812d508472 915 Hamap MF_01382 Protein translocase subunit SecA [secA]. 5 836 20.063 T 11-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AUP74_RS16700 2d7483145be84185166a84812d508472 915 Gene3D G3DSA:1.10.3060.10 647 834 1.4E-58 T 11-11-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 AUP74_RS16700 2d7483145be84185166a84812d508472 915 SUPERFAMILY SSF52540 362 409 1.97E-86 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS16700 2d7483145be84185166a84812d508472 915 SUPERFAMILY SSF52540 5 228 1.97E-86 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS16700 2d7483145be84185166a84812d508472 915 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 28 821 0.0 T 11-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AUP74_RS16700 2d7483145be84185166a84812d508472 915 PRINTS PR00906 SecA protein signature 170 190 2.6E-69 T 11-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AUP74_RS16700 2d7483145be84185166a84812d508472 915 PRINTS PR00906 SecA protein signature 407 420 2.6E-69 T 11-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AUP74_RS16700 2d7483145be84185166a84812d508472 915 PRINTS PR00906 SecA protein signature 63 87 2.6E-69 T 11-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AUP74_RS16700 2d7483145be84185166a84812d508472 915 PRINTS PR00906 SecA protein signature 117 127 2.6E-69 T 11-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AUP74_RS16700 2d7483145be84185166a84812d508472 915 PRINTS PR00906 SecA protein signature 333 355 2.6E-69 T 11-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AUP74_RS16700 2d7483145be84185166a84812d508472 915 PRINTS PR00906 SecA protein signature 101 115 2.6E-69 T 11-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AUP74_RS16700 2d7483145be84185166a84812d508472 915 PRINTS PR00906 SecA protein signature 370 387 2.6E-69 T 11-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AUP74_RS16700 2d7483145be84185166a84812d508472 915 Gene3D G3DSA:3.90.1440.10 230 362 2.2E-44 T 11-11-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 AUP74_RS16700 2d7483145be84185166a84812d508472 915 Pfam PF01043 SecA preprotein cross-linking domain 232 352 6.1E-36 T 11-11-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 AUP74_RS16700 2d7483145be84185166a84812d508472 915 Pfam PF07517 SecA DEAD-like domain 7 396 8.4E-135 T 11-11-2016 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 AUP74_RS16700 2d7483145be84185166a84812d508472 915 SUPERFAMILY SSF81767 227 362 1.1E-41 T 11-11-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 AUP74_RS16700 2d7483145be84185166a84812d508472 915 SMART SM00957 6 396 6.0E-298 T 11-11-2016 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 AUP74_RS16700 2d7483145be84185166a84812d508472 915 Gene3D G3DSA:3.40.50.300 363 410 1.1E-128 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS16700 2d7483145be84185166a84812d508472 915 Gene3D G3DSA:3.40.50.300 4 228 1.1E-128 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS15025 159ef1f1c450f89f426566317a9ba1ae 437 Pfam PF00924 Mechanosensitive ion channel 213 420 2.7E-46 T 11-11-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 AUP74_RS15025 159ef1f1c450f89f426566317a9ba1ae 437 SUPERFAMILY SSF50182 255 322 3.6E-14 T 11-11-2016 IPR010920 LSM domain AUP74_RS15025 159ef1f1c450f89f426566317a9ba1ae 437 Gene3D G3DSA:3.30.70.100 327 418 1.5E-11 T 11-11-2016 AUP74_RS15025 159ef1f1c450f89f426566317a9ba1ae 437 SUPERFAMILY SSF82861 170 254 3.14E-12 T 11-11-2016 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 AUP74_RS15025 159ef1f1c450f89f426566317a9ba1ae 437 SUPERFAMILY SSF82689 325 430 1.02E-20 T 11-11-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 AUP74_RS15025 159ef1f1c450f89f426566317a9ba1ae 437 Gene3D G3DSA:2.30.30.60 273 321 3.0E-13 T 11-11-2016 AUP74_RS15025 159ef1f1c450f89f426566317a9ba1ae 437 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 286 320 - T 11-11-2016 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 AUP74_RS00805 1a864914ee4d989d0559368f1512d848 447 SUPERFAMILY SSF52172 3 197 2.13E-31 T 11-11-2016 IPR011006 CheY-like superfamily AUP74_RS00805 1a864914ee4d989d0559368f1512d848 447 SUPERFAMILY SSF46689 361 445 3.72E-10 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS00805 1a864914ee4d989d0559368f1512d848 447 Gene3D G3DSA:3.40.50.2300 2 137 2.4E-28 T 11-11-2016 AUP74_RS00805 1a864914ee4d989d0559368f1512d848 447 Gene3D G3DSA:3.40.50.300 153 327 2.5E-50 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS00805 1a864914ee4d989d0559368f1512d848 447 Pfam PF00072 Response regulator receiver domain 4 119 1.3E-17 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS00805 1a864914ee4d989d0559368f1512d848 447 Gene3D G3DSA:1.10.10.60 406 445 3.9E-12 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS00805 1a864914ee4d989d0559368f1512d848 447 Pfam PF02954 Bacterial regulatory protein, Fis family 408 443 1.3E-12 T 11-11-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AUP74_RS00805 1a864914ee4d989d0559368f1512d848 447 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 242 257 - T 11-11-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 AUP74_RS00805 1a864914ee4d989d0559368f1512d848 447 Pfam PF00158 Sigma-54 interaction domain 156 323 1.4E-61 T 11-11-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 AUP74_RS00805 1a864914ee4d989d0559368f1512d848 447 Gene3D G3DSA:1.10.8.60 329 399 1.0E-17 T 11-11-2016 AUP74_RS00805 1a864914ee4d989d0559368f1512d848 447 SMART SM00382 175 319 2.0E-7 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS00805 1a864914ee4d989d0559368f1512d848 447 SMART SM00448 2 119 9.1E-18 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS00805 1a864914ee4d989d0559368f1512d848 447 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 409 426 4.3E-9 T 11-11-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AUP74_RS00805 1a864914ee4d989d0559368f1512d848 447 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 426 446 4.3E-9 T 11-11-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AUP74_RS00805 1a864914ee4d989d0559368f1512d848 447 SUPERFAMILY SSF52540 154 389 2.8E-60 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS00625 ce1a4fc55babe6be999ad83487b21b5e 114 Pfam PF02575 YbaB/EbfC DNA-binding family 8 104 4.0E-28 T 11-11-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family AUP74_RS00625 ce1a4fc55babe6be999ad83487b21b5e 114 Gene3D G3DSA:3.30.1310.10 2 114 6.4E-42 T 11-11-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family AUP74_RS00625 ce1a4fc55babe6be999ad83487b21b5e 114 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 2 98 21.695 T 11-11-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family AUP74_RS00625 ce1a4fc55babe6be999ad83487b21b5e 114 SUPERFAMILY SSF82607 8 99 3.14E-30 T 11-11-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family AUP74_RS00625 ce1a4fc55babe6be999ad83487b21b5e 114 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 3 104 4.4E-30 T 11-11-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family AUP74_RS00625 ce1a4fc55babe6be999ad83487b21b5e 114 PIRSF PIRSF004555 1 114 9.5E-34 T 11-11-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family AUP74_RS02005 199c4c87933a6651539fb4c27837481e 118 Gene3D G3DSA:2.60.40.420 20 118 8.3E-6 T 11-11-2016 IPR008972 Cupredoxin AUP74_RS02005 199c4c87933a6651539fb4c27837481e 118 Pfam PF13473 Cupredoxin-like domain 15 117 1.2E-28 T 11-11-2016 IPR028096 EfeO-type cupredoxin-like domain AUP74_RS02005 199c4c87933a6651539fb4c27837481e 118 SUPERFAMILY SSF49503 18 118 1.05E-15 T 11-11-2016 IPR008972 Cupredoxin AUP74_RS07735 64ce4e997284473f0ead316bf75d09f3 142 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 17 123 6.0E-10 T 11-11-2016 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 AUP74_RS07735 64ce4e997284473f0ead316bf75d09f3 142 SUPERFAMILY SSF54427 15 132 7.03E-23 T 11-11-2016 IPR032710 NTF2-like domain AUP74_RS07735 64ce4e997284473f0ead316bf75d09f3 142 Pfam PF14534 Domain of unknown function (DUF4440) 20 125 1.8E-14 T 11-11-2016 IPR027843 Domain of unknown function DUF4440 AUP74_RS07735 64ce4e997284473f0ead316bf75d09f3 142 Gene3D G3DSA:3.10.450.50 17 128 5.6E-17 T 11-11-2016 IPR032710 NTF2-like domain AUP74_RS16730 9aa56bbcdd7f437f9e1c70d26d6b9ba4 487 Pfam PF01225 Mur ligase family, catalytic domain 22 121 2.9E-28 T 11-11-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 AUP74_RS16730 9aa56bbcdd7f437f9e1c70d26d6b9ba4 487 SUPERFAMILY SSF51984 21 107 5.62E-30 T 11-11-2016 AUP74_RS16730 9aa56bbcdd7f437f9e1c70d26d6b9ba4 487 Gene3D G3DSA:3.40.1190.10 109 326 2.6E-81 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AUP74_RS16730 9aa56bbcdd7f437f9e1c70d26d6b9ba4 487 Pfam PF08245 Mur ligase middle domain 125 305 4.0E-29 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AUP74_RS16730 9aa56bbcdd7f437f9e1c70d26d6b9ba4 487 Pfam PF02875 Mur ligase family, glutamate ligase domain 325 418 5.1E-22 T 11-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AUP74_RS16730 9aa56bbcdd7f437f9e1c70d26d6b9ba4 487 SUPERFAMILY SSF53623 106 323 1.57E-72 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AUP74_RS16730 9aa56bbcdd7f437f9e1c70d26d6b9ba4 487 Gene3D G3DSA:3.90.190.20 327 477 5.3E-56 T 11-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AUP74_RS16730 9aa56bbcdd7f437f9e1c70d26d6b9ba4 487 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 20 481 43.681 T 11-11-2016 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AUP74_RS16730 9aa56bbcdd7f437f9e1c70d26d6b9ba4 487 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 22 475 3.4E-174 T 11-11-2016 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AUP74_RS16730 9aa56bbcdd7f437f9e1c70d26d6b9ba4 487 SUPERFAMILY SSF53244 324 476 3.66E-46 T 11-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AUP74_RS16730 9aa56bbcdd7f437f9e1c70d26d6b9ba4 487 Gene3D G3DSA:3.40.50.720 21 108 1.5E-38 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS00090 2f2d3eb16f8af60f6b3411dddbe4506c 344 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 9 336 8.7E-159 T 11-11-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 AUP74_RS00090 2f2d3eb16f8af60f6b3411dddbe4506c 344 Gene3D G3DSA:3.30.420.40 265 319 1.3E-33 T 11-11-2016 AUP74_RS00090 2f2d3eb16f8af60f6b3411dddbe4506c 344 Gene3D G3DSA:3.30.420.40 162 188 1.3E-33 T 11-11-2016 AUP74_RS00090 2f2d3eb16f8af60f6b3411dddbe4506c 344 Gene3D G3DSA:3.30.420.40 9 161 1.5E-44 T 11-11-2016 AUP74_RS00090 2f2d3eb16f8af60f6b3411dddbe4506c 344 Gene3D G3DSA:3.90.640.10 189 261 8.4E-28 T 11-11-2016 AUP74_RS00090 2f2d3eb16f8af60f6b3411dddbe4506c 344 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 302 328 2.7E-63 T 11-11-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 AUP74_RS00090 2f2d3eb16f8af60f6b3411dddbe4506c 344 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 70 93 2.7E-63 T 11-11-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 AUP74_RS00090 2f2d3eb16f8af60f6b3411dddbe4506c 344 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 189 209 2.7E-63 T 11-11-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 AUP74_RS00090 2f2d3eb16f8af60f6b3411dddbe4506c 344 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 134 153 2.7E-63 T 11-11-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 AUP74_RS00090 2f2d3eb16f8af60f6b3411dddbe4506c 344 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 50 68 2.7E-63 T 11-11-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 AUP74_RS00090 2f2d3eb16f8af60f6b3411dddbe4506c 344 Pfam PF06723 MreB/Mbl protein 11 336 3.6E-146 T 11-11-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 AUP74_RS00090 2f2d3eb16f8af60f6b3411dddbe4506c 344 SUPERFAMILY SSF53067 9 150 4.68E-38 T 11-11-2016 AUP74_RS00090 2f2d3eb16f8af60f6b3411dddbe4506c 344 SUPERFAMILY SSF53067 152 336 2.76E-49 T 11-11-2016 AUP74_RS03190 e6e500322da7ceddbc6fd44bcd55c6b8 167 TIGRFAM TIGR00809 secB: protein-export chaperone SecB 17 156 2.4E-51 T 11-11-2016 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 AUP74_RS03190 e6e500322da7ceddbc6fd44bcd55c6b8 167 Hamap MF_00821 Protein-export protein SecB [secB]. 1 153 32.22 T 11-11-2016 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 AUP74_RS03190 e6e500322da7ceddbc6fd44bcd55c6b8 167 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 21 38 2.3E-32 T 11-11-2016 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 AUP74_RS03190 e6e500322da7ceddbc6fd44bcd55c6b8 167 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 81 101 2.3E-32 T 11-11-2016 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 AUP74_RS03190 e6e500322da7ceddbc6fd44bcd55c6b8 167 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 131 149 2.3E-32 T 11-11-2016 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 AUP74_RS03190 e6e500322da7ceddbc6fd44bcd55c6b8 167 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 105 127 2.3E-32 T 11-11-2016 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 AUP74_RS03190 e6e500322da7ceddbc6fd44bcd55c6b8 167 Gene3D G3DSA:3.10.420.10 11 159 9.8E-57 T 11-11-2016 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 AUP74_RS03190 e6e500322da7ceddbc6fd44bcd55c6b8 167 SUPERFAMILY SSF54611 18 157 1.37E-49 T 11-11-2016 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 AUP74_RS03190 e6e500322da7ceddbc6fd44bcd55c6b8 167 Pfam PF02556 Preprotein translocase subunit SecB 15 151 1.9E-53 T 11-11-2016 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 AUP74_RS09100 6a5aa17e806d6a1635180c5ed6b29445 159 Pfam PF02082 Transcriptional regulator 1 83 7.1E-29 T 11-11-2016 IPR000944 Transcription regulator Rrf2-type AUP74_RS09100 6a5aa17e806d6a1635180c5ed6b29445 159 SUPERFAMILY SSF46785 2 133 2.72E-36 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS09100 6a5aa17e806d6a1635180c5ed6b29445 159 Gene3D G3DSA:1.10.10.10 1 136 9.8E-33 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS09100 6a5aa17e806d6a1635180c5ed6b29445 159 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 130 1.6E-46 T 11-11-2016 IPR000944 Transcription regulator Rrf2-type AUP74_RS09100 6a5aa17e806d6a1635180c5ed6b29445 159 TIGRFAM TIGR02010 IscR: iron-sulfur cluster assembly transcription factor IscR 1 133 1.0E-62 T 11-11-2016 IPR010242 Transcription factor HTH, IscR GO:0003690|GO:0003700|GO:0006355 AUP74_RS09100 6a5aa17e806d6a1635180c5ed6b29445 159 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 11-11-2016 IPR030489 Transcription regulator Rrf2-type, conserved site AUP74_RS02625 f6872c58cb7cae6cb629ec5488f8a14c 727 Pfam PF00593 TonB dependent receptor 467 726 9.9E-18 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS02625 f6872c58cb7cae6cb629ec5488f8a14c 727 SUPERFAMILY SSF56935 39 727 1.76E-114 T 11-11-2016 AUP74_RS02625 f6872c58cb7cae6cb629ec5488f8a14c 727 Pfam PF07715 TonB-dependent Receptor Plug Domain 57 162 2.7E-14 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS02625 f6872c58cb7cae6cb629ec5488f8a14c 727 Gene3D G3DSA:2.170.130.10 38 171 2.4E-28 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS02625 f6872c58cb7cae6cb629ec5488f8a14c 727 Gene3D G3DSA:2.40.170.20 172 727 1.6E-87 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS15670 a4a77b1196722eadbe8ed947620987a3 390 Pfam PF00155 Aminotransferase class I and II 31 385 1.0E-46 T 11-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AUP74_RS15670 a4a77b1196722eadbe8ed947620987a3 390 Gene3D G3DSA:3.90.1150.10 261 389 1.4E-24 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS15670 a4a77b1196722eadbe8ed947620987a3 390 TIGRFAM TIGR03538 DapC_gpp: succinyldiaminopimelate transaminase 1 389 2.8E-195 T 11-11-2016 IPR019878 Succinyldiaminopimelate transaminase, DapC, beta/gammaproteobacteria GO:0009016|GO:0009089 AUP74_RS15670 a4a77b1196722eadbe8ed947620987a3 390 Gene3D G3DSA:3.40.640.10 42 260 1.6E-66 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AUP74_RS15670 a4a77b1196722eadbe8ed947620987a3 390 SUPERFAMILY SSF53383 1 389 1.9E-94 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase AUP74_RS04870 ff6cf158e53f028424c0d723ae4fb951 493 Gene3D G3DSA:3.30.470.20 286 476 2.5E-15 T 11-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 AUP74_RS04870 ff6cf158e53f028424c0d723ae4fb951 493 Pfam PF08443 RimK-like ATP-grasp domain 282 459 7.5E-8 T 11-11-2016 IPR013651 ATP-grasp fold, RimK-type AUP74_RS04870 ff6cf158e53f028424c0d723ae4fb951 493 Gene3D G3DSA:3.40.50.20 227 285 1.3E-5 T 11-11-2016 IPR016185 Pre-ATP-grasp domain AUP74_RS04870 ff6cf158e53f028424c0d723ae4fb951 493 SUPERFAMILY SSF56059 273 480 1.51E-41 T 11-11-2016 AUP74_RS04870 ff6cf158e53f028424c0d723ae4fb951 493 Pfam PF14401 RimK-like ATPgrasp N-terminal domain 27 171 3.6E-42 T 11-11-2016 IPR025839 RimK-like ATPgrasp N-terminal domain AUP74_RS13165 c8da2de4a0ed3869cc9c7488dd32e20a 120 Pfam PF02635 DsrE/DsrF-like family 4 120 1.4E-23 T 11-11-2016 IPR003787 Sulphur relay, DsrE/F-like protein AUP74_RS13165 c8da2de4a0ed3869cc9c7488dd32e20a 120 Gene3D G3DSA:3.40.1260.10 5 120 6.5E-36 T 11-11-2016 IPR027396 DsrEFH-like AUP74_RS13165 c8da2de4a0ed3869cc9c7488dd32e20a 120 SUPERFAMILY SSF75169 5 120 4.19E-31 T 11-11-2016 IPR027396 DsrEFH-like AUP74_RS13165 c8da2de4a0ed3869cc9c7488dd32e20a 120 TIGRFAM TIGR03010 sulf_tusC_dsrF: sulfur relay protein TusC/DsrF 6 120 1.2E-32 T 11-11-2016 IPR017462 Sulphur relay, TusC/DsrF AUP74_RS13675 affee5f5b0d318db1ee0c60b9538c1b0 645 Pfam PF00753 Metallo-beta-lactamase superfamily 113 338 6.0E-40 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS13675 affee5f5b0d318db1ee0c60b9538c1b0 645 SUPERFAMILY SSF56281 15 516 8.12E-154 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS13675 affee5f5b0d318db1ee0c60b9538c1b0 645 SUPERFAMILY SSF55718 523 645 2.26E-37 T 11-11-2016 IPR003033 SCP2 sterol-binding domain AUP74_RS13675 affee5f5b0d318db1ee0c60b9538c1b0 645 Gene3D G3DSA:3.30.1050.10 527 634 6.5E-10 T 11-11-2016 IPR003033 SCP2 sterol-binding domain AUP74_RS13675 affee5f5b0d318db1ee0c60b9538c1b0 645 Pfam PF14864 Alkyl sulfatase C-terminal 521 645 1.7E-43 T 11-11-2016 IPR029229 Alkyl sulfatase, C-terminal AUP74_RS13675 affee5f5b0d318db1ee0c60b9538c1b0 645 SMART SM00849 116 338 2.9E-25 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS13675 affee5f5b0d318db1ee0c60b9538c1b0 645 Pfam PF14863 Alkyl sulfatase dimerisation 375 513 3.0E-58 T 11-11-2016 IPR029228 Alkyl sulfatase dimerisation domain GO:0046983 AUP74_RS13675 affee5f5b0d318db1ee0c60b9538c1b0 645 Gene3D G3DSA:3.60.15.10 101 202 1.4E-41 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS13675 affee5f5b0d318db1ee0c60b9538c1b0 645 Gene3D G3DSA:3.60.15.10 244 369 1.4E-41 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS10045 93a2a696dce30f8ffe05a22b8d7dbd22 302 SUPERFAMILY SSF82549 3 299 5.23E-40 T 11-11-2016 AUP74_RS10045 93a2a696dce30f8ffe05a22b8d7dbd22 302 Gene3D G3DSA:3.40.50.10170 2 158 7.6E-26 T 11-11-2016 AUP74_RS10045 93a2a696dce30f8ffe05a22b8d7dbd22 302 Pfam PF02645 Uncharacterised protein, DegV family COG1307 2 298 1.7E-41 T 11-11-2016 IPR003797 DegV AUP74_RS10045 93a2a696dce30f8ffe05a22b8d7dbd22 302 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 2 296 6.5E-33 T 11-11-2016 IPR003797 DegV AUP74_RS10045 93a2a696dce30f8ffe05a22b8d7dbd22 302 Gene3D G3DSA:3.30.1180.10 160 299 4.0E-12 T 11-11-2016 AUP74_RS08200 ce499cd5593388f82f209624541d6a02 132 Gene3D G3DSA:3.30.300.20 4 119 8.2E-36 T 11-11-2016 IPR015946 K homology domain-like, alpha/beta AUP74_RS08200 ce499cd5593388f82f209624541d6a02 132 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 10 99 2.0E-26 T 11-11-2016 IPR000238 Ribosome-binding factor A GO:0006364 AUP74_RS08200 ce499cd5593388f82f209624541d6a02 132 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 3 119 21.494 T 11-11-2016 IPR000238 Ribosome-binding factor A GO:0006364 AUP74_RS08200 ce499cd5593388f82f209624541d6a02 132 Pfam PF02033 Ribosome-binding factor A 7 112 2.9E-28 T 11-11-2016 IPR000238 Ribosome-binding factor A GO:0006364 AUP74_RS08200 ce499cd5593388f82f209624541d6a02 132 SUPERFAMILY SSF89919 2 104 7.33E-31 T 11-11-2016 IPR023799 Ribosome-binding factor A domain AUP74_RS08200 ce499cd5593388f82f209624541d6a02 132 ProSitePatterns PS01319 Ribosome-binding factor A signature. 78 99 - T 11-11-2016 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 AUP74_RS08200 ce499cd5593388f82f209624541d6a02 132 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 116 1.4E-30 T 11-11-2016 IPR000238 Ribosome-binding factor A GO:0006364 AUP74_RS00530 ccabb887c705fc4bef3aabb4d736a783 311 PIRSF PIRSF006621 1 297 1.2E-69 T 11-11-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 AUP74_RS00530 ccabb887c705fc4bef3aabb4d736a783 311 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 76 94 - T 11-11-2016 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 AUP74_RS00530 ccabb887c705fc4bef3aabb4d736a783 311 Hamap MF_02041 tRNA-dihydrouridine(20/20a) synthase [dusA]. 1 309 49.875 T 11-11-2016 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 AUP74_RS00530 ccabb887c705fc4bef3aabb4d736a783 311 TIGRFAM TIGR00742 yjbN: tRNA dihydrouridine synthase A 1 308 1.1E-143 T 11-11-2016 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 AUP74_RS00530 ccabb887c705fc4bef3aabb4d736a783 311 Pfam PF01207 Dihydrouridine synthase (Dus) 1 299 3.2E-82 T 11-11-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 AUP74_RS00530 ccabb887c705fc4bef3aabb4d736a783 311 Gene3D G3DSA:3.20.20.70 1 235 1.8E-70 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS00530 ccabb887c705fc4bef3aabb4d736a783 311 SUPERFAMILY SSF51395 1 304 1.33E-67 T 11-11-2016 AUP74_RS12630 32d2a514c556bd0641ab76f0be642ed2 273 Gene3D G3DSA:2.10.240.10 232 264 4.5E-10 T 11-11-2016 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain AUP74_RS12630 32d2a514c556bd0641ab76f0be642ed2 273 Gene3D G3DSA:3.40.50.80 89 228 7.1E-31 T 11-11-2016 AUP74_RS12630 32d2a514c556bd0641ab76f0be642ed2 273 Pfam PF00175 Oxidoreductase NAD-binding domain 112 212 1.4E-13 T 11-11-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AUP74_RS12630 32d2a514c556bd0641ab76f0be642ed2 273 PIRSF PIRSF006816 2 270 1.5E-58 T 11-11-2016 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 AUP74_RS12630 32d2a514c556bd0641ab76f0be642ed2 273 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 232 264 5.3E-9 T 11-11-2016 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain AUP74_RS12630 32d2a514c556bd0641ab76f0be642ed2 273 Gene3D G3DSA:2.40.30.10 7 88 8.3E-9 T 11-11-2016 AUP74_RS12630 32d2a514c556bd0641ab76f0be642ed2 273 SUPERFAMILY SSF63380 3 99 1.67E-13 T 11-11-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 AUP74_RS12630 32d2a514c556bd0641ab76f0be642ed2 273 SUPERFAMILY SSF52343 94 264 5.11E-33 T 11-11-2016 AUP74_RS12630 32d2a514c556bd0641ab76f0be642ed2 273 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 150 161 7.1E-6 T 11-11-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AUP74_RS12630 32d2a514c556bd0641ab76f0be642ed2 273 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 110 129 7.1E-6 T 11-11-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AUP74_RS12630 32d2a514c556bd0641ab76f0be642ed2 273 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 138 147 7.1E-6 T 11-11-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AUP74_RS12630 32d2a514c556bd0641ab76f0be642ed2 273 PRINTS PR00410 Phenol hydroxylase reductase family signature 110 129 1.7E-7 T 11-11-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 AUP74_RS12630 32d2a514c556bd0641ab76f0be642ed2 273 PRINTS PR00410 Phenol hydroxylase reductase family signature 35 47 1.7E-7 T 11-11-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 AUP74_RS12630 32d2a514c556bd0641ab76f0be642ed2 273 PRINTS PR00410 Phenol hydroxylase reductase family signature 200 208 1.7E-7 T 11-11-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 AUP74_RS08110 81a72e8a8cf80f5e1a73a61829de1c33 1044 Pfam PF13432 Tetratricopeptide repeat 378 409 0.0018 T 11-11-2016 AUP74_RS08110 81a72e8a8cf80f5e1a73a61829de1c33 1044 Pfam PF13432 Tetratricopeptide repeat 486 542 0.0081 T 11-11-2016 AUP74_RS08110 81a72e8a8cf80f5e1a73a61829de1c33 1044 Gene3D G3DSA:1.25.40.10 772 855 1.4E-5 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS08110 81a72e8a8cf80f5e1a73a61829de1c33 1044 Gene3D G3DSA:1.25.40.10 584 771 1.4E-9 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS08110 81a72e8a8cf80f5e1a73a61829de1c33 1044 Gene3D G3DSA:1.25.40.10 253 322 5.2E-14 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS08110 81a72e8a8cf80f5e1a73a61829de1c33 1044 Gene3D G3DSA:1.25.40.10 372 407 5.2E-14 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS08110 81a72e8a8cf80f5e1a73a61829de1c33 1044 Pfam PF13525 Outer membrane lipoprotein 213 307 1.4E-6 T 11-11-2016 AUP74_RS08110 81a72e8a8cf80f5e1a73a61829de1c33 1044 Gene3D G3DSA:1.25.40.10 194 248 1.3E-7 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS08110 81a72e8a8cf80f5e1a73a61829de1c33 1044 Gene3D G3DSA:1.25.40.10 44 87 1.3E-7 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS08110 81a72e8a8cf80f5e1a73a61829de1c33 1044 SMART SM00028 289 322 28.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS08110 81a72e8a8cf80f5e1a73a61829de1c33 1044 SMART SM00028 372 405 7.3 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS08110 81a72e8a8cf80f5e1a73a61829de1c33 1044 SMART SM00028 252 285 0.35 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS08110 81a72e8a8cf80f5e1a73a61829de1c33 1044 SMART SM00028 637 670 160.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS08110 81a72e8a8cf80f5e1a73a61829de1c33 1044 SMART SM00028 793 826 110.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS08110 81a72e8a8cf80f5e1a73a61829de1c33 1044 SMART SM00028 215 248 450.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS08110 81a72e8a8cf80f5e1a73a61829de1c33 1044 SMART SM00028 682 715 38.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS08110 81a72e8a8cf80f5e1a73a61829de1c33 1044 SUPERFAMILY SSF48452 640 725 1.74E-13 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS08110 81a72e8a8cf80f5e1a73a61829de1c33 1044 SUPERFAMILY SSF48452 193 320 1.74E-13 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS08110 81a72e8a8cf80f5e1a73a61829de1c33 1044 SUPERFAMILY SSF48452 370 408 1.74E-13 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS08110 81a72e8a8cf80f5e1a73a61829de1c33 1044 SUPERFAMILY SSF48452 800 825 1.74E-13 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS08110 81a72e8a8cf80f5e1a73a61829de1c33 1044 SUPERFAMILY SSF48452 750 844 3.42E-5 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS08110 81a72e8a8cf80f5e1a73a61829de1c33 1044 Pfam PF13174 Tetratricopeptide repeat 794 824 0.047 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS10275 af794b8bd9685d3efa30fd362e1663d8 412 SUPERFAMILY SSF53633 4 241 7.46E-74 T 11-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase AUP74_RS10275 af794b8bd9685d3efa30fd362e1663d8 412 SUPERFAMILY SSF55021 331 406 7.64E-25 T 11-11-2016 AUP74_RS10275 af794b8bd9685d3efa30fd362e1663d8 412 SUPERFAMILY SSF55021 249 328 1.26E-16 T 11-11-2016 AUP74_RS10275 af794b8bd9685d3efa30fd362e1663d8 412 Gene3D G3DSA:3.40.1160.10 1 245 1.7E-73 T 11-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase AUP74_RS10275 af794b8bd9685d3efa30fd362e1663d8 412 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 61 404 3.6E-119 T 11-11-2016 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 AUP74_RS10275 af794b8bd9685d3efa30fd362e1663d8 412 Pfam PF13840 ACT domain 338 401 4.3E-14 T 11-11-2016 IPR027795 GATS-like ACT domain AUP74_RS10275 af794b8bd9685d3efa30fd362e1663d8 412 Pfam PF00696 Amino acid kinase family 3 229 1.1E-49 T 11-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase AUP74_RS10275 af794b8bd9685d3efa30fd362e1663d8 412 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 11-11-2016 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 AUP74_RS10275 af794b8bd9685d3efa30fd362e1663d8 412 PIRSF PIRSF000726 56 411 4.1E-145 T 11-11-2016 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 AUP74_RS10275 af794b8bd9685d3efa30fd362e1663d8 412 Pfam PF01842 ACT domain 268 327 2.3E-6 T 11-11-2016 IPR002912 ACT domain GO:0008152|GO:0016597 AUP74_RS10275 af794b8bd9685d3efa30fd362e1663d8 412 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 406 1.6E-135 T 11-11-2016 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 AUP74_RS04040 ec6654c947a4e4341f5c3393859863a6 291 Pfam PF08340 Domain of unknown function (DUF1732) 207 291 1.8E-34 T 11-11-2016 IPR013551 Domain of unknown function DUF1732 AUP74_RS04040 ec6654c947a4e4341f5c3393859863a6 291 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 6 291 1.7E-91 T 11-11-2016 IPR005229 Conserved hypothetical protein CHP00255 AUP74_RS04040 ec6654c947a4e4341f5c3393859863a6 291 Pfam PF03755 YicC-like family, N-terminal region 6 157 4.7E-42 T 11-11-2016 IPR013527 YicC-like, N-terminal AUP74_RS16815 38e3aac27ed9b56833615c10f6e27f4c 199 Pfam PF04972 BON domain 132 197 7.9E-17 T 11-11-2016 IPR007055 BON domain AUP74_RS16815 38e3aac27ed9b56833615c10f6e27f4c 199 Pfam PF04972 BON domain 55 122 4.1E-16 T 11-11-2016 IPR007055 BON domain AUP74_RS16815 38e3aac27ed9b56833615c10f6e27f4c 199 SMART SM00749 63 123 27.0 T 11-11-2016 IPR014004 Transport-associated and nodulation domain, bacteria AUP74_RS16815 38e3aac27ed9b56833615c10f6e27f4c 199 SMART SM00749 137 199 1.8E-5 T 11-11-2016 IPR014004 Transport-associated and nodulation domain, bacteria AUP74_RS08330 a0bd3b4378b61e817d417443c7b13e06 178 Gene3D G3DSA:3.90.80.10 3 175 9.8E-60 T 11-11-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 AUP74_RS08330 a0bd3b4378b61e817d417443c7b13e06 178 SUPERFAMILY SSF50324 3 174 4.06E-67 T 11-11-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 AUP74_RS08330 a0bd3b4378b61e817d417443c7b13e06 178 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 14 174 35.879 T 11-11-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 AUP74_RS08330 a0bd3b4378b61e817d417443c7b13e06 178 Pfam PF00719 Inorganic pyrophosphatase 18 173 2.9E-52 T 11-11-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 AUP74_RS08330 a0bd3b4378b61e817d417443c7b13e06 178 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 66 72 - T 11-11-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 AUP74_RS14635 81d8279d3f2025777660867b1ec5d28b 216 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 188 1.5E-60 T 11-11-2016 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 AUP74_RS14635 81d8279d3f2025777660867b1ec5d28b 216 Gene3D G3DSA:3.20.19.10 4 194 1.9E-43 T 11-11-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel AUP74_RS14635 81d8279d3f2025777660867b1ec5d28b 216 SUPERFAMILY SSF52016 2 198 2.55E-53 T 11-11-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel AUP74_RS14635 81d8279d3f2025777660867b1ec5d28b 216 Pfam PF00694 Aconitase C-terminal domain 1 125 6.2E-29 T 11-11-2016 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS14635 81d8279d3f2025777660867b1ec5d28b 216 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 203 38.354 T 11-11-2016 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 AUP74_RS12600 088839fb7802f26941b221e1d5830dc1 84 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 43 59 1.6E-14 T 11-11-2016 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AUP74_RS12600 088839fb7802f26941b221e1d5830dc1 84 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 22 38 1.6E-14 T 11-11-2016 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AUP74_RS12600 088839fb7802f26941b221e1d5830dc1 84 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 1.6E-14 T 11-11-2016 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AUP74_RS12600 088839fb7802f26941b221e1d5830dc1 84 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 61 73 1.6E-14 T 11-11-2016 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AUP74_RS12600 088839fb7802f26941b221e1d5830dc1 84 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 75 1.4E-23 T 11-11-2016 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AUP74_RS12600 088839fb7802f26941b221e1d5830dc1 84 Pfam PF01455 HupF/HypC family 1 67 9.8E-25 T 11-11-2016 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AUP74_RS12600 088839fb7802f26941b221e1d5830dc1 84 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 11-11-2016 IPR019812 Hydrogenase assembly chaperone, conserved site AUP74_RS12600 088839fb7802f26941b221e1d5830dc1 84 SUPERFAMILY SSF159127 1 78 1.07E-21 T 11-11-2016 AUP74_RS03325 063003bc2d5ab83d777c8e0a3886c000 234 ProDom PD080812 PLASMID Y4OB BMEII097 AGR_L_107P MLL2216 BMEII0977 ATU4831 13 119 7.0E-23 T 11-11-2016 IPR020358 Uncharacterised protein family Y4oB AUP74_RS03325 063003bc2d5ab83d777c8e0a3886c000 234 Pfam PF09722 Protein of unknown function (DUF2384) 72 121 1.3E-7 T 11-11-2016 IPR024467 Domain of unknown function DUF2384 AUP74_RS01875 19340c46ba418b77217400ae0b4c0ea5 435 Gene3D G3DSA:3.50.50.60 1 129 8.9E-19 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS01875 19340c46ba418b77217400ae0b4c0ea5 435 Gene3D G3DSA:3.50.50.60 130 346 1.4E-32 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS01875 19340c46ba418b77217400ae0b4c0ea5 435 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 1.2E-13 T 11-11-2016 AUP74_RS01875 19340c46ba418b77217400ae0b4c0ea5 435 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 120 138 1.2E-13 T 11-11-2016 AUP74_RS01875 19340c46ba418b77217400ae0b4c0ea5 435 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 175 193 1.2E-13 T 11-11-2016 AUP74_RS01875 19340c46ba418b77217400ae0b4c0ea5 435 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 296 318 1.2E-13 T 11-11-2016 AUP74_RS01875 19340c46ba418b77217400ae0b4c0ea5 435 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 339 8.1E-59 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS01875 19340c46ba418b77217400ae0b4c0ea5 435 SUPERFAMILY SSF51905 1 225 1.69E-28 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS01875 19340c46ba418b77217400ae0b4c0ea5 435 SUPERFAMILY SSF51905 168 352 3.19E-24 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS01875 19340c46ba418b77217400ae0b4c0ea5 435 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 175 200 3.2E-9 T 11-11-2016 AUP74_RS01875 19340c46ba418b77217400ae0b4c0ea5 435 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 3.2E-9 T 11-11-2016 AUP74_RS01875 19340c46ba418b77217400ae0b4c0ea5 435 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 311 318 3.2E-9 T 11-11-2016 AUP74_RS13700 6906e2c9630b4612a91698c9b8af6430 169 ProSitePatterns PS00519 AsnC-type HTH domain signature. 26 52 - T 11-11-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site AUP74_RS13700 6906e2c9630b4612a91698c9b8af6430 169 SUPERFAMILY SSF46785 8 65 3.03E-18 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS13700 6906e2c9630b4612a91698c9b8af6430 169 Pfam PF01037 Lrp/AsnC ligand binding domain 74 147 5.8E-22 T 11-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AUP74_RS13700 6906e2c9630b4612a91698c9b8af6430 169 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 24 35 7.8E-19 T 11-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 AUP74_RS13700 6906e2c9630b4612a91698c9b8af6430 169 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 8 24 7.8E-19 T 11-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 AUP74_RS13700 6906e2c9630b4612a91698c9b8af6430 169 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 35 54 7.8E-19 T 11-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 AUP74_RS13700 6906e2c9630b4612a91698c9b8af6430 169 SUPERFAMILY SSF54909 69 155 2.82E-21 T 11-11-2016 IPR011008 Dimeric alpha-beta barrel AUP74_RS13700 6906e2c9630b4612a91698c9b8af6430 169 Pfam PF13412 Winged helix-turn-helix DNA-binding 8 55 1.6E-20 T 11-11-2016 AUP74_RS13700 6906e2c9630b4612a91698c9b8af6430 169 Gene3D G3DSA:3.30.70.920 61 156 4.5E-31 T 11-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AUP74_RS13700 6906e2c9630b4612a91698c9b8af6430 169 Gene3D G3DSA:1.10.10.10 9 60 9.5E-26 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS13700 6906e2c9630b4612a91698c9b8af6430 169 SMART SM00344 8 117 1.9E-44 T 11-11-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AUP74_RS09245 a1938a66ae0b9a5e36a68fa8363411fc 610 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 90 110 3.1E-7 T 11-11-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 AUP74_RS09245 a1938a66ae0b9a5e36a68fa8363411fc 610 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 269 291 3.1E-7 T 11-11-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 AUP74_RS09245 a1938a66ae0b9a5e36a68fa8363411fc 610 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 422 444 3.1E-7 T 11-11-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 AUP74_RS09245 a1938a66ae0b9a5e36a68fa8363411fc 610 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 88 113 7.6E-57 T 11-11-2016 AUP74_RS09245 a1938a66ae0b9a5e36a68fa8363411fc 610 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 163 184 7.6E-57 T 11-11-2016 AUP74_RS09245 a1938a66ae0b9a5e36a68fa8363411fc 610 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 251 277 7.6E-57 T 11-11-2016 AUP74_RS09245 a1938a66ae0b9a5e36a68fa8363411fc 610 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 423 442 7.6E-57 T 11-11-2016 AUP74_RS09245 a1938a66ae0b9a5e36a68fa8363411fc 610 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 116 136 7.6E-57 T 11-11-2016 AUP74_RS09245 a1938a66ae0b9a5e36a68fa8363411fc 610 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 319 331 7.6E-57 T 11-11-2016 AUP74_RS09245 a1938a66ae0b9a5e36a68fa8363411fc 610 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 229 250 7.6E-57 T 11-11-2016 AUP74_RS09245 a1938a66ae0b9a5e36a68fa8363411fc 610 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 72 127 1.1E-20 T 11-11-2016 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09245 a1938a66ae0b9a5e36a68fa8363411fc 610 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 4 607 1.7E-198 T 11-11-2016 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09245 a1938a66ae0b9a5e36a68fa8363411fc 610 Pfam PF00361 Proton-conducting membrane transporter 139 430 2.3E-90 T 11-11-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS15300 8f693001866ef715d8c0f2bf7409ac8c 265 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 263 17.119 T 11-11-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 AUP74_RS15300 8f693001866ef715d8c0f2bf7409ac8c 265 Pfam PF02673 Bacitracin resistance protein BacA 7 257 2.3E-74 T 11-11-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 AUP74_RS15300 8f693001866ef715d8c0f2bf7409ac8c 265 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 7 256 7.6E-68 T 11-11-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 AUP74_RS06160 6eedcbeb6477dde020fae8da46c6b143 355 SMART SM00729 52 264 2.2E-39 T 11-11-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 AUP74_RS06160 6eedcbeb6477dde020fae8da46c6b143 355 PIRSF PIRSF001619 2 328 1.7E-136 T 11-11-2016 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 AUP74_RS06160 6eedcbeb6477dde020fae8da46c6b143 355 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 229 320 7.8E-19 T 11-11-2016 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 AUP74_RS06160 6eedcbeb6477dde020fae8da46c6b143 355 SUPERFAMILY SSF102114 14 322 3.27E-94 T 11-11-2016 AUP74_RS06160 6eedcbeb6477dde020fae8da46c6b143 355 Pfam PF04055 Radical SAM superfamily 59 210 2.2E-16 T 11-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 AUP74_RS06160 6eedcbeb6477dde020fae8da46c6b143 355 Gene3D G3DSA:3.20.20.70 14 322 1.6E-104 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS06160 6eedcbeb6477dde020fae8da46c6b143 355 TIGRFAM TIGR00433 bioB: biotin synthase 23 319 2.0E-126 T 11-11-2016 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 AUP74_RS06160 6eedcbeb6477dde020fae8da46c6b143 355 Hamap MF_01694 Biotin synthase [bioB]. 14 322 42.726 T 11-11-2016 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 AUP74_RS06160 6eedcbeb6477dde020fae8da46c6b143 355 SMART SM00876 229 321 4.8E-48 T 11-11-2016 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 AUP74_RS00760 d5eaed2cbe0b14bdb82f321ae2194a77 347 Pfam PF00248 Aldo/keto reductase family 16 338 4.4E-71 T 11-11-2016 IPR023210 NADP-dependent oxidoreductase domain AUP74_RS00760 d5eaed2cbe0b14bdb82f321ae2194a77 347 SUPERFAMILY SSF51430 1 345 2.62E-103 T 11-11-2016 IPR023210 NADP-dependent oxidoreductase domain AUP74_RS00760 d5eaed2cbe0b14bdb82f321ae2194a77 347 Gene3D G3DSA:3.20.20.100 1 344 2.0E-102 T 11-11-2016 IPR023210 NADP-dependent oxidoreductase domain AUP74_RS15500 bc58806f37347078dfa3b8a84f6944ad 280 Gene3D G3DSA:3.30.160.20 143 221 9.1E-37 T 11-11-2016 IPR014720 Double-stranded RNA-binding domain AUP74_RS15500 bc58806f37347078dfa3b8a84f6944ad 280 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 1 278 1.2E-135 T 11-11-2016 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 AUP74_RS15500 bc58806f37347078dfa3b8a84f6944ad 280 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 160 176 - T 11-11-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 AUP74_RS15500 bc58806f37347078dfa3b8a84f6944ad 280 Pfam PF03462 PCRF domain 6 135 4.1E-43 T 11-11-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 AUP74_RS15500 bc58806f37347078dfa3b8a84f6944ad 280 Pfam PF00472 RF-1 domain 144 252 3.1E-38 T 11-11-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 AUP74_RS15500 bc58806f37347078dfa3b8a84f6944ad 280 SUPERFAMILY SSF75620 4 277 5.36E-117 T 11-11-2016 AUP74_RS15500 bc58806f37347078dfa3b8a84f6944ad 280 SMART SM00937 1 110 5.3E-52 T 11-11-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 AUP74_RS15365 d36bd9d978602e6b43b32ccde3dd639a 308 Hamap MF_00367 GTPase Era [era]. 15 305 36.029 T 11-11-2016 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 AUP74_RS15365 d36bd9d978602e6b43b32ccde3dd639a 308 Pfam PF01926 50S ribosome-binding GTPase 20 134 6.9E-24 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 AUP74_RS15365 d36bd9d978602e6b43b32ccde3dd639a 308 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 19 177 1.5E-30 T 11-11-2016 IPR005225 Small GTP-binding protein domain GO:0005525 AUP74_RS15365 d36bd9d978602e6b43b32ccde3dd639a 308 Gene3D G3DSA:3.30.300.20 203 302 1.6E-39 T 11-11-2016 IPR015946 K homology domain-like, alpha/beta AUP74_RS15365 d36bd9d978602e6b43b32ccde3dd639a 308 Gene3D G3DSA:3.40.50.300 14 202 2.9E-44 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS15365 d36bd9d978602e6b43b32ccde3dd639a 308 Pfam PF07650 KH domain 218 293 3.7E-18 T 11-11-2016 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS15365 d36bd9d978602e6b43b32ccde3dd639a 308 TIGRFAM TIGR00436 era: GTP-binding protein Era 18 288 4.5E-98 T 11-11-2016 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 AUP74_RS15365 d36bd9d978602e6b43b32ccde3dd639a 308 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 69 84 1.5E-6 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 AUP74_RS15365 d36bd9d978602e6b43b32ccde3dd639a 308 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 20 40 1.5E-6 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 AUP74_RS15365 d36bd9d978602e6b43b32ccde3dd639a 308 SUPERFAMILY SSF54814 191 306 1.96E-41 T 11-11-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 AUP74_RS15365 d36bd9d978602e6b43b32ccde3dd639a 308 SUPERFAMILY SSF52540 20 214 3.78E-46 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS08430 5e972adfe3f598ff5e71f52bb5a00af5 158 Pfam PF02590 Predicted SPOUT methyltransferase 1 157 1.1E-51 T 11-11-2016 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AUP74_RS08430 5e972adfe3f598ff5e71f52bb5a00af5 158 Gene3D G3DSA:3.40.1280.10 1 158 3.3E-56 T 11-11-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AUP74_RS08430 5e972adfe3f598ff5e71f52bb5a00af5 158 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 158 29.089 T 11-11-2016 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AUP74_RS08430 5e972adfe3f598ff5e71f52bb5a00af5 158 PIRSF PIRSF004505 1 158 3.9E-47 T 11-11-2016 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AUP74_RS08430 5e972adfe3f598ff5e71f52bb5a00af5 158 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 2 158 1.2E-57 T 11-11-2016 IPR016051 Ribosomal RNA large subunit methyltransferase H GO:0005737|GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AUP74_RS08430 5e972adfe3f598ff5e71f52bb5a00af5 158 SUPERFAMILY SSF75217 1 156 2.35E-50 T 11-11-2016 IPR029028 Alpha/beta knot methyltransferases AUP74_RS16210 818e367d6fb726adfe22522eeaf5db22 111 Gene3D G3DSA:3.40.30.10 7 101 6.7E-32 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS16210 818e367d6fb726adfe22522eeaf5db22 111 Pfam PF00462 Glutaredoxin 16 80 8.3E-18 T 11-11-2016 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 AUP74_RS16210 818e367d6fb726adfe22522eeaf5db22 111 PIRSF PIRSF005894 1 107 6.9E-50 T 11-11-2016 IPR014434 Monothiol glutaredoxin AUP74_RS16210 818e367d6fb726adfe22522eeaf5db22 111 SUPERFAMILY SSF52833 1 102 4.05E-34 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS16210 818e367d6fb726adfe22522eeaf5db22 111 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 4 100 1.3E-46 T 11-11-2016 IPR004480 Monothiol glutaredoxin-related AUP74_RS06100 7c36969413547ffb648a6d6b258bcf53 135 Gene3D G3DSA:1.10.1660.10 66 128 9.4E-16 T 11-11-2016 AUP74_RS06100 7c36969413547ffb648a6d6b258bcf53 135 SUPERFAMILY SSF46955 13 122 4.76E-27 T 11-11-2016 IPR009061 Putative DNA-binding domain AUP74_RS06100 7c36969413547ffb648a6d6b258bcf53 135 Gene3D G3DSA:1.10.1660.10 12 65 4.1E-22 T 11-11-2016 AUP74_RS06100 7c36969413547ffb648a6d6b258bcf53 135 SMART SM00422 13 80 6.9E-21 T 11-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AUP74_RS06100 7c36969413547ffb648a6d6b258bcf53 135 Pfam PF13411 MerR HTH family regulatory protein 13 78 1.0E-17 T 11-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AUP74_RS12900 aab443b3e9452ad98b2ac17a4c761664 403 TIGRFAM TIGR00016 ackA: acetate kinase 5 398 1.5E-146 T 11-11-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AUP74_RS12900 aab443b3e9452ad98b2ac17a4c761664 403 Gene3D G3DSA:3.30.420.40 106 206 4.4E-10 T 11-11-2016 AUP74_RS12900 aab443b3e9452ad98b2ac17a4c761664 403 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 205 222 - T 11-11-2016 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AUP74_RS12900 aab443b3e9452ad98b2ac17a4c761664 403 Hamap MF_00020 Acetate kinase [ackA]. 1 401 174.269 T 11-11-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AUP74_RS12900 aab443b3e9452ad98b2ac17a4c761664 403 SUPERFAMILY SSF53067 158 399 3.39E-84 T 11-11-2016 AUP74_RS12900 aab443b3e9452ad98b2ac17a4c761664 403 SUPERFAMILY SSF53067 6 198 2.52E-60 T 11-11-2016 AUP74_RS12900 aab443b3e9452ad98b2ac17a4c761664 403 Gene3D G3DSA:3.30.420.40 207 397 2.7E-71 T 11-11-2016 AUP74_RS12900 aab443b3e9452ad98b2ac17a4c761664 403 PRINTS PR00471 Acetate kinase family signature 302 315 4.0E-43 T 11-11-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AUP74_RS12900 aab443b3e9452ad98b2ac17a4c761664 403 PRINTS PR00471 Acetate kinase family signature 175 188 4.0E-43 T 11-11-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AUP74_RS12900 aab443b3e9452ad98b2ac17a4c761664 403 PRINTS PR00471 Acetate kinase family signature 7 18 4.0E-43 T 11-11-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AUP74_RS12900 aab443b3e9452ad98b2ac17a4c761664 403 PRINTS PR00471 Acetate kinase family signature 324 340 4.0E-43 T 11-11-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AUP74_RS12900 aab443b3e9452ad98b2ac17a4c761664 403 PRINTS PR00471 Acetate kinase family signature 205 226 4.0E-43 T 11-11-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AUP74_RS12900 aab443b3e9452ad98b2ac17a4c761664 403 PRINTS PR00471 Acetate kinase family signature 379 391 4.0E-43 T 11-11-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AUP74_RS12900 aab443b3e9452ad98b2ac17a4c761664 403 PIRSF PIRSF000722 3 402 1.1E-135 T 11-11-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AUP74_RS12900 aab443b3e9452ad98b2ac17a4c761664 403 Pfam PF00871 Acetokinase family 7 392 3.9E-142 T 11-11-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AUP74_RS07950 3a8750c57f268fdd0dd91a28551816bc 372 SMART SM00271 4 62 3.1E-33 T 11-11-2016 IPR001623 DnaJ domain AUP74_RS07950 3a8750c57f268fdd0dd91a28551816bc 372 SUPERFAMILY SSF49493 209 263 4.06E-22 T 11-11-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 AUP74_RS07950 3a8750c57f268fdd0dd91a28551816bc 372 SUPERFAMILY SSF49493 110 148 4.06E-22 T 11-11-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 AUP74_RS07950 3a8750c57f268fdd0dd91a28551816bc 372 SUPERFAMILY SSF49493 255 340 4.84E-22 T 11-11-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 AUP74_RS07950 3a8750c57f268fdd0dd91a28551816bc 372 PRINTS PR00625 DnaJ domain signature 25 40 1.7E-33 T 11-11-2016 IPR001623 DnaJ domain AUP74_RS07950 3a8750c57f268fdd0dd91a28551816bc 372 PRINTS PR00625 DnaJ domain signature 62 81 1.7E-33 T 11-11-2016 IPR001623 DnaJ domain AUP74_RS07950 3a8750c57f268fdd0dd91a28551816bc 372 PRINTS PR00625 DnaJ domain signature 42 62 1.7E-33 T 11-11-2016 IPR001623 DnaJ domain AUP74_RS07950 3a8750c57f268fdd0dd91a28551816bc 372 PRINTS PR00625 DnaJ domain signature 7 25 1.7E-33 T 11-11-2016 IPR001623 DnaJ domain AUP74_RS07950 3a8750c57f268fdd0dd91a28551816bc 372 SUPERFAMILY SSF57938 130 207 7.59E-22 T 11-11-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 AUP74_RS07950 3a8750c57f268fdd0dd91a28551816bc 372 ProSitePatterns PS00636 Nt-dnaJ domain signature. 47 66 - T 11-11-2016 IPR018253 DnaJ domain, conserved site AUP74_RS07950 3a8750c57f268fdd0dd91a28551816bc 372 Pfam PF00226 DnaJ domain 5 67 1.2E-27 T 11-11-2016 IPR001623 DnaJ domain AUP74_RS07950 3a8750c57f268fdd0dd91a28551816bc 372 SUPERFAMILY SSF46565 1 106 2.09E-38 T 11-11-2016 IPR001623 DnaJ domain AUP74_RS07950 3a8750c57f268fdd0dd91a28551816bc 372 Gene3D G3DSA:1.10.287.110 1 100 1.6E-38 T 11-11-2016 IPR001623 DnaJ domain AUP74_RS07950 3a8750c57f268fdd0dd91a28551816bc 372 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 366 42.605 T 11-11-2016 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 AUP74_RS07950 3a8750c57f268fdd0dd91a28551816bc 372 Gene3D G3DSA:2.10.230.10 137 206 1.9E-23 T 11-11-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 AUP74_RS07950 3a8750c57f268fdd0dd91a28551816bc 372 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 344 3.3E-138 T 11-11-2016 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 AUP74_RS07950 3a8750c57f268fdd0dd91a28551816bc 372 Gene3D G3DSA:2.60.260.20 104 136 5.2E-24 T 11-11-2016 AUP74_RS07950 3a8750c57f268fdd0dd91a28551816bc 372 Gene3D G3DSA:2.60.260.20 207 250 5.2E-24 T 11-11-2016 AUP74_RS07950 3a8750c57f268fdd0dd91a28551816bc 372 Gene3D G3DSA:2.60.260.20 252 329 2.2E-22 T 11-11-2016 AUP74_RS07950 3a8750c57f268fdd0dd91a28551816bc 372 Pfam PF01556 DnaJ C terminal domain 117 329 7.0E-43 T 11-11-2016 IPR002939 Chaperone DnaJ, C-terminal AUP74_RS07950 3a8750c57f268fdd0dd91a28551816bc 372 Pfam PF00684 DnaJ central domain 143 203 7.0E-14 T 11-11-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 AUP74_RS01560 d9600a358e35aefde4b4befa6365f51e 377 Gene3D G3DSA:3.40.430.10 133 371 2.2E-74 T 11-11-2016 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 AUP74_RS01560 d9600a358e35aefde4b4befa6365f51e 377 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 6 103 3.7E-18 T 11-11-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 AUP74_RS01560 d9600a358e35aefde4b4befa6365f51e 377 Pfam PF01872 RibD C-terminal domain 150 365 7.8E-54 T 11-11-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 AUP74_RS01560 d9600a358e35aefde4b4befa6365f51e 377 SUPERFAMILY SSF53597 148 370 4.42E-58 T 11-11-2016 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 AUP74_RS01560 d9600a358e35aefde4b4befa6365f51e 377 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 9 369 1.7E-117 T 11-11-2016 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 AUP74_RS01560 d9600a358e35aefde4b4befa6365f51e 377 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 91 - T 11-11-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 AUP74_RS01560 d9600a358e35aefde4b4befa6365f51e 377 PIRSF PIRSF006769 2 375 1.3E-125 T 11-11-2016 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 AUP74_RS01560 d9600a358e35aefde4b4befa6365f51e 377 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 149 372 4.2E-60 T 11-11-2016 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 AUP74_RS01560 d9600a358e35aefde4b4befa6365f51e 377 Gene3D G3DSA:3.40.140.10 6 132 3.2E-33 T 11-11-2016 AUP74_RS01560 d9600a358e35aefde4b4befa6365f51e 377 SUPERFAMILY SSF53927 6 146 2.8E-45 T 11-11-2016 IPR016193 Cytidine deaminase-like GO:0003824 AUP74_RS13100 d925b9d3af4cd6d642fe6b61c27f7309 340 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 36 331 2.9E-73 T 11-11-2016 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS13100 d925b9d3af4cd6d642fe6b61c27f7309 340 Pfam PF00849 RNA pseudouridylate synthase 120 267 3.3E-28 T 11-11-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS13100 d925b9d3af4cd6d642fe6b61c27f7309 340 Pfam PF01479 S4 domain 39 85 1.2E-9 T 11-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 AUP74_RS13100 d925b9d3af4cd6d642fe6b61c27f7309 340 Gene3D G3DSA:3.10.290.10 39 87 2.3E-8 T 11-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 AUP74_RS13100 d925b9d3af4cd6d642fe6b61c27f7309 340 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 158 172 - T 11-11-2016 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS13100 d925b9d3af4cd6d642fe6b61c27f7309 340 SUPERFAMILY SSF55174 38 89 2.22E-9 T 11-11-2016 AUP74_RS13100 d925b9d3af4cd6d642fe6b61c27f7309 340 SUPERFAMILY SSF55120 107 331 1.18E-52 T 11-11-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS13100 d925b9d3af4cd6d642fe6b61c27f7309 340 SMART SM00363 39 97 1.4E-7 T 11-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 AUP74_RS14450 08880543ee081e1dec8546e29e1b78ee 443 SUPERFAMILY SSF103473 15 427 2.88E-48 T 11-11-2016 IPR020846 Major facilitator superfamily domain AUP74_RS14450 08880543ee081e1dec8546e29e1b78ee 443 Gene3D G3DSA:1.20.1250.20 19 203 1.2E-23 T 11-11-2016 AUP74_RS14450 08880543ee081e1dec8546e29e1b78ee 443 Gene3D G3DSA:1.20.1250.20 232 429 5.7E-20 T 11-11-2016 AUP74_RS14450 08880543ee081e1dec8546e29e1b78ee 443 ProSitePatterns PS00216 Sugar transport proteins signature 1. 77 93 - T 11-11-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AUP74_RS14450 08880543ee081e1dec8546e29e1b78ee 443 Pfam PF07690 Major Facilitator Superfamily 24 386 3.6E-34 T 11-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AUP74_RS11460 bca86cb0a895d90d6cdaa8f38140cce7 836 SMART SM00491 662 801 5.2E-15 T 11-11-2016 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 AUP74_RS11460 bca86cb0a895d90d6cdaa8f38140cce7 836 Pfam PF00270 DEAD/DEAH box helicase 234 296 3.0E-4 T 11-11-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AUP74_RS11460 bca86cb0a895d90d6cdaa8f38140cce7 836 Gene3D G3DSA:3.40.50.300 379 430 2.1E-11 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11460 bca86cb0a895d90d6cdaa8f38140cce7 836 Gene3D G3DSA:3.40.50.300 233 324 2.1E-11 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11460 bca86cb0a895d90d6cdaa8f38140cce7 836 Gene3D G3DSA:3.40.50.300 571 597 2.1E-11 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11460 bca86cb0a895d90d6cdaa8f38140cce7 836 SMART SM00488 214 464 5.8E-6 T 11-11-2016 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 AUP74_RS11460 bca86cb0a895d90d6cdaa8f38140cce7 836 Pfam PF13307 Helicase C-terminal domain 647 813 4.4E-31 T 11-11-2016 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 AUP74_RS11460 bca86cb0a895d90d6cdaa8f38140cce7 836 Pfam PF06733 DEAD_2 313 429 9.7E-12 T 11-11-2016 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 AUP74_RS11460 bca86cb0a895d90d6cdaa8f38140cce7 836 SUPERFAMILY SSF52540 577 794 7.45E-15 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11460 bca86cb0a895d90d6cdaa8f38140cce7 836 SUPERFAMILY SSF52540 237 295 7.45E-15 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11460 bca86cb0a895d90d6cdaa8f38140cce7 836 SUPERFAMILY SSF52540 360 433 7.45E-15 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03930 2fba1d551c82e18d2c3734f661b0ecf7 284 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 16 283 8.0E-123 T 11-11-2016 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 AUP74_RS03930 2fba1d551c82e18d2c3734f661b0ecf7 284 Hamap MF_00961 RNA polymerase sigma factor RpoH [rpoH]. 2 284 51.722 T 11-11-2016 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 AUP74_RS03930 2fba1d551c82e18d2c3734f661b0ecf7 284 Gene3D G3DSA:1.10.601.10 17 123 1.1E-34 T 11-11-2016 AUP74_RS03930 2fba1d551c82e18d2c3734f661b0ecf7 284 SUPERFAMILY SSF88946 15 123 4.97E-39 T 11-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS03930 2fba1d551c82e18d2c3734f661b0ecf7 284 SUPERFAMILY SSF88659 197 283 7.66E-18 T 11-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS03930 2fba1d551c82e18d2c3734f661b0ecf7 284 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 252 278 - T 11-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS03930 2fba1d551c82e18d2c3734f661b0ecf7 284 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 78 91 - T 11-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS03930 2fba1d551c82e18d2c3734f661b0ecf7 284 Pfam PF04545 Sigma-70, region 4 229 280 5.2E-16 T 11-11-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS03930 2fba1d551c82e18d2c3734f661b0ecf7 284 Pfam PF04542 Sigma-70 region 2 54 123 5.1E-17 T 11-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS03930 2fba1d551c82e18d2c3734f661b0ecf7 284 Gene3D G3DSA:1.10.10.10 226 283 1.9E-19 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS03930 2fba1d551c82e18d2c3734f661b0ecf7 284 PRINTS PR00046 Major sigma-70 factor signature 252 267 5.5E-18 T 11-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS03930 2fba1d551c82e18d2c3734f661b0ecf7 284 PRINTS PR00046 Major sigma-70 factor signature 78 91 5.5E-18 T 11-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS03930 2fba1d551c82e18d2c3734f661b0ecf7 284 PRINTS PR00046 Major sigma-70 factor signature 267 278 5.5E-18 T 11-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS03930 2fba1d551c82e18d2c3734f661b0ecf7 284 PRINTS PR00046 Major sigma-70 factor signature 233 245 5.5E-18 T 11-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS03930 2fba1d551c82e18d2c3734f661b0ecf7 284 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 49 281 1.1E-33 T 11-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS09000 4acc472f1506689835ccfaa567d6f9cf 578 SUPERFAMILY SSF52374 110 455 4.13E-88 T 11-11-2016 AUP74_RS09000 4acc472f1506689835ccfaa567d6f9cf 578 Gene3D G3DSA:3.40.50.620 110 454 1.4E-109 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS09000 4acc472f1506689835ccfaa567d6f9cf 578 SUPERFAMILY SSF55190 1 96 1.44E-23 T 11-11-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 AUP74_RS09000 4acc472f1506689835ccfaa567d6f9cf 578 Hamap MF_00123 Arginine--tRNA ligase [argS]. 5 578 27.339 T 11-11-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AUP74_RS09000 4acc472f1506689835ccfaa567d6f9cf 578 SMART SM01016 1 87 4.4E-34 T 11-11-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 AUP74_RS09000 4acc472f1506689835ccfaa567d6f9cf 578 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 123 134 - T 11-11-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS09000 4acc472f1506689835ccfaa567d6f9cf 578 SMART SM00836 461 578 1.3E-39 T 11-11-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 AUP74_RS09000 4acc472f1506689835ccfaa567d6f9cf 578 Gene3D G3DSA:3.30.1360.70 1 103 2.9E-35 T 11-11-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 AUP74_RS09000 4acc472f1506689835ccfaa567d6f9cf 578 Pfam PF05746 DALR anticodon binding domain 461 578 9.0E-34 T 11-11-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 AUP74_RS09000 4acc472f1506689835ccfaa567d6f9cf 578 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 7 87 3.7E-22 T 11-11-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 AUP74_RS09000 4acc472f1506689835ccfaa567d6f9cf 578 SUPERFAMILY SSF47323 456 578 2.09E-35 T 11-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS09000 4acc472f1506689835ccfaa567d6f9cf 578 Gene3D G3DSA:1.10.730.10 455 578 1.9E-37 T 11-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS09000 4acc472f1506689835ccfaa567d6f9cf 578 Pfam PF00750 tRNA synthetases class I (R) 111 447 9.9E-136 T 11-11-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AUP74_RS09000 4acc472f1506689835ccfaa567d6f9cf 578 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 3 578 7.0E-175 T 11-11-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AUP74_RS09000 4acc472f1506689835ccfaa567d6f9cf 578 PRINTS PR01038 Arginyl-tRNA synthetase signature 154 167 7.2E-26 T 11-11-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AUP74_RS09000 4acc472f1506689835ccfaa567d6f9cf 578 PRINTS PR01038 Arginyl-tRNA synthetase signature 130 146 7.2E-26 T 11-11-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AUP74_RS09000 4acc472f1506689835ccfaa567d6f9cf 578 PRINTS PR01038 Arginyl-tRNA synthetase signature 115 130 7.2E-26 T 11-11-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AUP74_RS09000 4acc472f1506689835ccfaa567d6f9cf 578 PRINTS PR01038 Arginyl-tRNA synthetase signature 304 325 7.2E-26 T 11-11-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AUP74_RS03845 3d912c09de33496ec9bfa959c4298f2a 70 Pfam PF01197 Ribosomal protein L31 1 65 2.7E-31 T 11-11-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS03845 3d912c09de33496ec9bfa959c4298f2a 70 ProSitePatterns PS01143 Ribosomal protein L31 signature. 35 56 - T 11-11-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS03845 3d912c09de33496ec9bfa959c4298f2a 70 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 68 29.656 T 11-11-2016 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS03845 3d912c09de33496ec9bfa959c4298f2a 70 SUPERFAMILY SSF143800 1 66 1.18E-27 T 11-11-2016 AUP74_RS03845 3d912c09de33496ec9bfa959c4298f2a 70 PRINTS PR01249 Ribosomal protein L31 signature 46 64 2.1E-21 T 11-11-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS03845 3d912c09de33496ec9bfa959c4298f2a 70 PRINTS PR01249 Ribosomal protein L31 signature 31 46 2.1E-21 T 11-11-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS03845 3d912c09de33496ec9bfa959c4298f2a 70 PRINTS PR01249 Ribosomal protein L31 signature 2 19 2.1E-21 T 11-11-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS03845 3d912c09de33496ec9bfa959c4298f2a 70 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 66 1.6E-33 T 11-11-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS13495 5c9dc074b5800a663b936c15e96c0374 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 71 5.5E-15 T 11-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AUP74_RS13495 5c9dc074b5800a663b936c15e96c0374 202 Gene3D G3DSA:1.10.10.60 20 71 7.1E-19 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS13495 5c9dc074b5800a663b936c15e96c0374 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 2.9E-9 T 11-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AUP74_RS13495 5c9dc074b5800a663b936c15e96c0374 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 2.9E-9 T 11-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AUP74_RS13495 5c9dc074b5800a663b936c15e96c0374 202 Gene3D G3DSA:1.10.357.10 72 199 9.3E-27 T 11-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 AUP74_RS13495 5c9dc074b5800a663b936c15e96c0374 202 SUPERFAMILY SSF46689 19 99 5.08E-18 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS13495 5c9dc074b5800a663b936c15e96c0374 202 SUPERFAMILY SSF48498 95 199 3.56E-6 T 11-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AUP74_RS04685 a6eaf959a2d57196aa70866cff00a4cc 371 SUPERFAMILY SSF46626 263 359 4.87E-23 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS04685 a6eaf959a2d57196aa70866cff00a4cc 371 SUPERFAMILY SSF81464 14 109 6.21E-29 T 11-11-2016 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS04685 a6eaf959a2d57196aa70866cff00a4cc 371 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 29 248 5.7E-61 T 11-11-2016 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS04685 a6eaf959a2d57196aa70866cff00a4cc 371 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 271 345 9.8E-13 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS04685 a6eaf959a2d57196aa70866cff00a4cc 371 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 17 100 4.5E-15 T 11-11-2016 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS04685 a6eaf959a2d57196aa70866cff00a4cc 371 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 117 238 9.5E-37 T 11-11-2016 IPR002429 Cytochrome c oxidase subunit II C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS04685 a6eaf959a2d57196aa70866cff00a4cc 371 PRINTS PR01166 Cytochrome c oxidase subunit II signature 89 109 2.8E-40 T 11-11-2016 AUP74_RS04685 a6eaf959a2d57196aa70866cff00a4cc 371 PRINTS PR01166 Cytochrome c oxidase subunit II signature 202 219 2.8E-40 T 11-11-2016 AUP74_RS04685 a6eaf959a2d57196aa70866cff00a4cc 371 PRINTS PR01166 Cytochrome c oxidase subunit II signature 182 202 2.8E-40 T 11-11-2016 AUP74_RS04685 a6eaf959a2d57196aa70866cff00a4cc 371 PRINTS PR01166 Cytochrome c oxidase subunit II signature 158 179 2.8E-40 T 11-11-2016 AUP74_RS04685 a6eaf959a2d57196aa70866cff00a4cc 371 PRINTS PR01166 Cytochrome c oxidase subunit II signature 77 89 2.8E-40 T 11-11-2016 AUP74_RS04685 a6eaf959a2d57196aa70866cff00a4cc 371 PRINTS PR01166 Cytochrome c oxidase subunit II signature 111 130 2.8E-40 T 11-11-2016 AUP74_RS04685 a6eaf959a2d57196aa70866cff00a4cc 371 PRINTS PR01166 Cytochrome c oxidase subunit II signature 220 237 2.8E-40 T 11-11-2016 AUP74_RS04685 a6eaf959a2d57196aa70866cff00a4cc 371 Gene3D G3DSA:2.60.40.420 106 283 2.3E-56 T 11-11-2016 IPR008972 Cupredoxin AUP74_RS04685 a6eaf959a2d57196aa70866cff00a4cc 371 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 183 231 - T 11-11-2016 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS04685 a6eaf959a2d57196aa70866cff00a4cc 371 Gene3D G3DSA:1.10.760.10 284 363 6.5E-23 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS04685 a6eaf959a2d57196aa70866cff00a4cc 371 Gene3D G3DSA:1.10.287.90 17 105 4.3E-28 T 11-11-2016 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS04685 a6eaf959a2d57196aa70866cff00a4cc 371 SUPERFAMILY SSF49503 109 303 2.74E-51 T 11-11-2016 IPR008972 Cupredoxin AUP74_RS02010 6e23bd710d0e7b4d01f94001159886d1 451 SUPERFAMILY SSF55874 273 439 2.36E-35 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS02010 6e23bd710d0e7b4d01f94001159886d1 451 SMART SM00387 327 441 5.6E-31 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS02010 6e23bd710d0e7b4d01f94001159886d1 451 SMART SM00388 215 283 1.5E-12 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS02010 6e23bd710d0e7b4d01f94001159886d1 451 SUPERFAMILY SSF47384 199 281 1.51E-14 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS02010 6e23bd710d0e7b4d01f94001159886d1 451 Gene3D G3DSA:1.10.287.130 207 268 2.4E-10 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS02010 6e23bd710d0e7b4d01f94001159886d1 451 Pfam PF00512 His Kinase A (phospho-acceptor) domain 217 279 1.3E-12 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS02010 6e23bd710d0e7b4d01f94001159886d1 451 Gene3D G3DSA:3.30.565.10 269 439 8.1E-37 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS02010 6e23bd710d0e7b4d01f94001159886d1 451 Pfam PF00672 HAMP domain 145 209 6.3E-8 T 11-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 AUP74_RS02010 6e23bd710d0e7b4d01f94001159886d1 451 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 328 438 3.6E-18 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS02010 6e23bd710d0e7b4d01f94001159886d1 451 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 392 8.8E-10 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS02010 6e23bd710d0e7b4d01f94001159886d1 451 PRINTS PR00344 Bacterial sensor protein C-terminal signature 364 378 8.8E-10 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS02010 6e23bd710d0e7b4d01f94001159886d1 451 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 418 8.8E-10 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS08465 b9b057e311aed6c2904e4816791523bf 234 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 23 205 8.0E-64 T 11-11-2016 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 AUP74_RS08465 b9b057e311aed6c2904e4816791523bf 234 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 67 82 - T 11-11-2016 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 AUP74_RS08465 b9b057e311aed6c2904e4816791523bf 234 Gene3D G3DSA:3.90.1550.10 3 205 1.3E-68 T 11-11-2016 AUP74_RS08465 b9b057e311aed6c2904e4816791523bf 234 SUPERFAMILY SSF55681 3 206 2.98E-65 T 11-11-2016 AUP74_RS08465 b9b057e311aed6c2904e4816791523bf 234 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 71 124 3.0E-15 T 11-11-2016 AUP74_RS08465 b9b057e311aed6c2904e4816791523bf 234 Hamap MF_00013 Octanoyltransferase [lipB]. 1 208 37.315 T 11-11-2016 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 AUP74_RS08465 b9b057e311aed6c2904e4816791523bf 234 PIRSF PIRSF016262 1 218 3.0E-58 T 11-11-2016 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 AUP74_RS08465 b9b057e311aed6c2904e4816791523bf 234 Pfam PF03099 Biotin/lipoate A/B protein ligase family 55 160 2.3E-8 T 11-11-2016 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 AUP74_RS10410 c198ac135773c79698db9945d5e6485e 572 Pfam PF14792 DNA polymerase beta palm 163 211 1.6E-6 T 11-11-2016 IPR028207 DNA polymerase beta, palm domain AUP74_RS10410 c198ac135773c79698db9945d5e6485e 572 Gene3D G3DSA:1.10.150.110 2 86 5.9E-22 T 11-11-2016 IPR027421 DNA polymerase family X lyase domain AUP74_RS10410 c198ac135773c79698db9945d5e6485e 572 SUPERFAMILY SSF158702 59 149 4.97E-8 T 11-11-2016 AUP74_RS10410 c198ac135773c79698db9945d5e6485e 572 SMART SM00483 3 316 4.0E-22 T 11-11-2016 IPR002054 DNA-directed DNA polymerase X GO:0003677|GO:0003887 AUP74_RS10410 c198ac135773c79698db9945d5e6485e 572 SUPERFAMILY SSF81301 161 316 1.96E-39 T 11-11-2016 AUP74_RS10410 c198ac135773c79698db9945d5e6485e 572 SMART SM00278 94 113 0.43 T 11-11-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AUP74_RS10410 c198ac135773c79698db9945d5e6485e 572 SMART SM00278 129 148 33.0 T 11-11-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AUP74_RS10410 c198ac135773c79698db9945d5e6485e 572 SMART SM00278 54 73 980.0 T 11-11-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AUP74_RS10410 c198ac135773c79698db9945d5e6485e 572 Gene3D G3DSA:1.10.150.20 94 148 2.6E-6 T 11-11-2016 AUP74_RS10410 c198ac135773c79698db9945d5e6485e 572 Gene3D G3DSA:3.20.20.140 338 568 1.3E-47 T 11-11-2016 AUP74_RS10410 c198ac135773c79698db9945d5e6485e 572 Pfam PF14716 Helix-hairpin-helix domain 5 73 5.3E-22 T 11-11-2016 IPR010996 DNA polymerase beta-like, N-terminal domain AUP74_RS10410 c198ac135773c79698db9945d5e6485e 572 Pfam PF14520 Helix-hairpin-helix domain 95 151 1.5E-10 T 11-11-2016 AUP74_RS10410 c198ac135773c79698db9945d5e6485e 572 SMART SM00481 340 419 2.8E-10 T 11-11-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 AUP74_RS10410 c198ac135773c79698db9945d5e6485e 572 Gene3D G3DSA:3.30.460.10 149 257 3.8E-16 T 11-11-2016 AUP74_RS10410 c198ac135773c79698db9945d5e6485e 572 SUPERFAMILY SSF89550 339 569 1.2E-48 T 11-11-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AUP74_RS10410 c198ac135773c79698db9945d5e6485e 572 PIRSF PIRSF005047 3 572 6.9E-225 T 11-11-2016 IPR022311 Uncharacterised conserved protein UCP005047, YshC KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS10410 c198ac135773c79698db9945d5e6485e 572 Gene3D G3DSA:3.30.210.10 258 316 3.6E-21 T 11-11-2016 IPR029398 DNA polymerase beta, thumb domain AUP74_RS10410 c198ac135773c79698db9945d5e6485e 572 Pfam PF14791 DNA polymerase beta thumb 256 316 6.5E-17 T 11-11-2016 IPR029398 DNA polymerase beta, thumb domain AUP74_RS10410 c198ac135773c79698db9945d5e6485e 572 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 298 315 3.1E-5 T 11-11-2016 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS10410 c198ac135773c79698db9945d5e6485e 572 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 61 78 3.1E-5 T 11-11-2016 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS10410 c198ac135773c79698db9945d5e6485e 572 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 241 249 3.1E-5 T 11-11-2016 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS10410 c198ac135773c79698db9945d5e6485e 572 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 256 263 3.1E-5 T 11-11-2016 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS10410 c198ac135773c79698db9945d5e6485e 572 SUPERFAMILY SSF47802 1 84 1.31E-19 T 11-11-2016 IPR010996 DNA polymerase beta-like, N-terminal domain AUP74_RS10225 fae1727fc02966299f2fc00bf52a1e88 887 SMART SM00534 612 799 8.6E-120 T 11-11-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 AUP74_RS10225 fae1727fc02966299f2fc00bf52a1e88 887 Pfam PF05190 MutS family domain IV 433 523 7.5E-32 T 11-11-2016 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 AUP74_RS10225 fae1727fc02966299f2fc00bf52a1e88 887 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 13 879 25.524 T 11-11-2016 IPR005748 DNA mismatch repair protein MutS, type 1 GO:0005524|GO:0006298|GO:0030983 AUP74_RS10225 fae1727fc02966299f2fc00bf52a1e88 887 Pfam PF05192 MutS domain III 276 564 9.2E-40 T 11-11-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 AUP74_RS10225 fae1727fc02966299f2fc00bf52a1e88 887 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 13 885 0.0 T 11-11-2016 IPR005748 DNA mismatch repair protein MutS, type 1 GO:0005524|GO:0006298|GO:0030983 AUP74_RS10225 fae1727fc02966299f2fc00bf52a1e88 887 Pfam PF01624 MutS domain I 14 125 1.7E-41 T 11-11-2016 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 AUP74_RS10225 fae1727fc02966299f2fc00bf52a1e88 887 SUPERFAMILY SSF55271 7 121 1.07E-41 T 11-11-2016 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 AUP74_RS10225 fae1727fc02966299f2fc00bf52a1e88 887 SUPERFAMILY SSF53150 120 272 1.02E-41 T 11-11-2016 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 AUP74_RS10225 fae1727fc02966299f2fc00bf52a1e88 887 Pfam PF05188 MutS domain II 134 259 1.8E-25 T 11-11-2016 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 AUP74_RS10225 fae1727fc02966299f2fc00bf52a1e88 887 Gene3D G3DSA:3.30.420.110 132 262 5.2E-39 T 11-11-2016 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 AUP74_RS10225 fae1727fc02966299f2fc00bf52a1e88 887 Gene3D G3DSA:3.40.50.300 573 802 1.7E-82 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS10225 fae1727fc02966299f2fc00bf52a1e88 887 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 693 709 - T 11-11-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 AUP74_RS10225 fae1727fc02966299f2fc00bf52a1e88 887 SMART SM00533 289 596 1.6E-111 T 11-11-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 AUP74_RS10225 fae1727fc02966299f2fc00bf52a1e88 887 Gene3D G3DSA:3.40.1170.10 7 126 5.9E-52 T 11-11-2016 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 AUP74_RS10225 fae1727fc02966299f2fc00bf52a1e88 887 SUPERFAMILY SSF52540 573 802 5.31E-59 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS10225 fae1727fc02966299f2fc00bf52a1e88 887 Gene3D G3DSA:1.10.1420.10 322 482 7.7E-57 T 11-11-2016 AUP74_RS10225 fae1727fc02966299f2fc00bf52a1e88 887 Pfam PF00488 MutS domain V 615 802 2.1E-85 T 11-11-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 AUP74_RS10225 fae1727fc02966299f2fc00bf52a1e88 887 SUPERFAMILY SSF48334 273 569 7.32E-90 T 11-11-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 AUP74_RS10800 27badf531b9d60c45246d849e874306c 215 Pfam PF04231 Endonuclease I 41 211 6.4E-42 T 11-11-2016 IPR007346 Endonuclease I GO:0004518 AUP74_RS10800 27badf531b9d60c45246d849e874306c 215 SUPERFAMILY SSF54060 2 213 4.47E-78 T 11-11-2016 AUP74_RS09515 68cb9017a6ba1df2ef3098f23be62f84 787 Pfam PF07793 Protein of unknown function (DUF1631) 34 778 8.9E-189 T 11-11-2016 IPR012434 Protein of unknown function DUF1631 AUP74_RS02245 3b4854573e7a0c25f0d11333d77df264 318 ProSitePatterns PS00770 Aminotransferases class-IV signature. 194 222 - T 11-11-2016 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 AUP74_RS02245 3b4854573e7a0c25f0d11333d77df264 318 SUPERFAMILY SSF56752 1 303 3.53E-103 T 11-11-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 AUP74_RS02245 3b4854573e7a0c25f0d11333d77df264 318 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 11 306 2.4E-133 T 11-11-2016 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108 AUP74_RS02245 3b4854573e7a0c25f0d11333d77df264 318 Gene3D G3DSA:3.30.470.10 8 130 3.3E-40 T 11-11-2016 AUP74_RS02245 3b4854573e7a0c25f0d11333d77df264 318 Gene3D G3DSA:3.20.10.10 135 295 3.5E-60 T 11-11-2016 AUP74_RS02245 3b4854573e7a0c25f0d11333d77df264 318 Pfam PF01063 Amino-transferase class IV 36 265 1.5E-54 T 11-11-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 AUP74_RS05375 950f1008773518fbf22656096d9e2db1 296 Pfam PF00753 Metallo-beta-lactamase superfamily 61 247 9.5E-28 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS05375 950f1008773518fbf22656096d9e2db1 296 SMART SM00849 59 247 4.7E-26 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS05375 950f1008773518fbf22656096d9e2db1 296 ProSitePatterns PS00743 Beta-lactamases class B signature 1. 103 123 - T 11-11-2016 IPR001018 Beta-lactamase, class-B, conserved site GO:0008270|GO:0008800|GO:0017001 AUP74_RS05375 950f1008773518fbf22656096d9e2db1 296 Gene3D G3DSA:3.60.15.10 29 275 6.3E-46 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS05375 950f1008773518fbf22656096d9e2db1 296 SUPERFAMILY SSF56281 34 264 1.17E-42 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS16115 c8a5e7bf6d7a314821de67ba7aee0395 357 SMART SM01329 4 353 2.0E-213 T 11-11-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AUP74_RS16115 c8a5e7bf6d7a314821de67ba7aee0395 357 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 3 357 52.949 T 11-11-2016 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 AUP74_RS16115 c8a5e7bf6d7a314821de67ba7aee0395 357 SUPERFAMILY SSF53659 2 356 2.5E-126 T 11-11-2016 AUP74_RS16115 c8a5e7bf6d7a314821de67ba7aee0395 357 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 4 351 1.9E-162 T 11-11-2016 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 AUP74_RS16115 c8a5e7bf6d7a314821de67ba7aee0395 357 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 4 353 2.6E-141 T 11-11-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AUP74_RS16115 c8a5e7bf6d7a314821de67ba7aee0395 357 Gene3D G3DSA:3.40.718.10 2 356 3.3E-135 T 11-11-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AUP74_RS16115 c8a5e7bf6d7a314821de67ba7aee0395 357 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 244 263 - T 11-11-2016 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 AUP74_RS15160 0a800b4dfbaaef8141170032ffd2cbd7 601 Pfam PF07969 Amidohydrolase family 86 575 9.2E-92 T 11-11-2016 IPR013108 Amidohydrolase 3 AUP74_RS15160 0a800b4dfbaaef8141170032ffd2cbd7 601 Gene3D G3DSA:2.30.40.10 38 99 5.9E-19 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS15160 0a800b4dfbaaef8141170032ffd2cbd7 601 Gene3D G3DSA:2.30.40.10 548 577 5.9E-19 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS15160 0a800b4dfbaaef8141170032ffd2cbd7 601 Gene3D G3DSA:3.20.20.140 100 119 4.3E-23 T 11-11-2016 AUP74_RS15160 0a800b4dfbaaef8141170032ffd2cbd7 601 Gene3D G3DSA:3.20.20.140 239 517 4.3E-23 T 11-11-2016 AUP74_RS15160 0a800b4dfbaaef8141170032ffd2cbd7 601 Gene3D G3DSA:2.30.40.10 518 547 3.3E-5 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS15160 0a800b4dfbaaef8141170032ffd2cbd7 601 SUPERFAMILY SSF51556 97 156 3.44E-30 T 11-11-2016 IPR032466 Metal-dependent hydrolase AUP74_RS15160 0a800b4dfbaaef8141170032ffd2cbd7 601 SUPERFAMILY SSF51556 233 536 3.44E-30 T 11-11-2016 IPR032466 Metal-dependent hydrolase AUP74_RS15160 0a800b4dfbaaef8141170032ffd2cbd7 601 SUPERFAMILY SSF51338 34 98 1.06E-20 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS15160 0a800b4dfbaaef8141170032ffd2cbd7 601 SUPERFAMILY SSF51338 535 576 1.06E-20 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS13465 34153adcbdf64322c549bda392dfb47f 75 Pfam PF04102 SlyX 9 75 2.8E-19 T 11-11-2016 IPR007236 SlyX AUP74_RS13465 34153adcbdf64322c549bda392dfb47f 75 Hamap MF_00715 Protein SlyX [slyX]. 7 75 13.911 T 11-11-2016 IPR007236 SlyX AUP74_RS13465 34153adcbdf64322c549bda392dfb47f 75 Gene3D G3DSA:1.20.5.300 3 52 2.9E-14 T 11-11-2016 AUP74_RS07325 80d99b246eeb7fc3915f8db134298ae8 511 SUPERFAMILY SSF110921 393 501 3.27E-27 T 11-11-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AUP74_RS07325 80d99b246eeb7fc3915f8db134298ae8 511 SMART SM00917 373 502 1.6E-41 T 11-11-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AUP74_RS07325 80d99b246eeb7fc3915f8db134298ae8 511 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 7 499 5.9E-219 T 11-11-2016 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AUP74_RS07325 80d99b246eeb7fc3915f8db134298ae8 511 SUPERFAMILY SSF51569 3 294 2.01E-98 T 11-11-2016 AUP74_RS07325 80d99b246eeb7fc3915f8db134298ae8 511 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 5 511 43.042 T 11-11-2016 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AUP74_RS07325 80d99b246eeb7fc3915f8db134298ae8 511 Pfam PF08502 LeuA allosteric (dimerisation) domain 373 500 1.3E-34 T 11-11-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AUP74_RS07325 80d99b246eeb7fc3915f8db134298ae8 511 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 202 215 - T 11-11-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AUP74_RS07325 80d99b246eeb7fc3915f8db134298ae8 511 Pfam PF00682 HMGL-like 8 276 3.4E-98 T 11-11-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 AUP74_RS07325 80d99b246eeb7fc3915f8db134298ae8 511 Gene3D G3DSA:3.20.20.70 3 349 3.2E-148 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS07325 80d99b246eeb7fc3915f8db134298ae8 511 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 15 31 - T 11-11-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AUP74_RS05060 a47a008141449a8ef840b138b36dc3d8 153 Gene3D G3DSA:3.30.1950.10 9 74 8.7E-15 T 11-11-2016 AUP74_RS05060 a47a008141449a8ef840b138b36dc3d8 153 Pfam PF10531 SLBB domain 81 128 3.1E-10 T 11-11-2016 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS05060 a47a008141449a8ef840b138b36dc3d8 153 Pfam PF02563 Polysaccharide biosynthesis/export protein 2 74 3.1E-15 T 11-11-2016 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 AUP74_RS05060 a47a008141449a8ef840b138b36dc3d8 153 Gene3D G3DSA:3.10.560.10 75 149 1.3E-12 T 11-11-2016 AUP74_RS09740 169c35ed02908f14d214f115fb993a12 203 SUPERFAMILY SSF52266 14 192 6.72E-50 T 11-11-2016 IPR013830 SGNH hydrolase-type esterase domain AUP74_RS09740 169c35ed02908f14d214f115fb993a12 203 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 17 176 2.9E-25 T 11-11-2016 IPR013830 SGNH hydrolase-type esterase domain AUP74_RS09740 169c35ed02908f14d214f115fb993a12 203 Gene3D G3DSA:3.40.50.1110 14 194 7.4E-55 T 11-11-2016 IPR013830 SGNH hydrolase-type esterase domain AUP74_RS11745 cf221d57ae8e5582a9555a94454270e8 324 Gene3D G3DSA:3.40.50.2000 141 292 3.1E-23 T 11-11-2016 AUP74_RS11745 cf221d57ae8e5582a9555a94454270e8 324 SUPERFAMILY SSF53756 25 317 1.79E-64 T 11-11-2016 AUP74_RS11745 cf221d57ae8e5582a9555a94454270e8 324 Pfam PF00534 Glycosyl transferases group 1 141 292 2.0E-28 T 11-11-2016 IPR001296 Glycosyl transferase, family 1 AUP74_RS15975 f8a24612aabf51dfb54ff501ca82b04f 118 SUPERFAMILY SSF52833 4 111 7.35E-27 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS15975 f8a24612aabf51dfb54ff501ca82b04f 118 Pfam PF00578 AhpC/TSA family 4 91 8.3E-13 T 11-11-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AUP74_RS15975 f8a24612aabf51dfb54ff501ca82b04f 118 Gene3D G3DSA:3.40.30.10 4 110 1.5E-25 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS12705 066a3b45185372fe7d02c459f5df967c 254 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 202 10.014 T 11-11-2016 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 AUP74_RS12705 066a3b45185372fe7d02c459f5df967c 254 Pfam PF00213 ATP synthase delta (OSCP) subunit 177 241 4.3E-8 T 11-11-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 AUP74_RS12705 066a3b45185372fe7d02c459f5df967c 254 Pfam PF00430 ATP synthase B/B' CF(0) 7 137 1.5E-13 T 11-11-2016 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 AUP74_RS06910 0829f2bb415489a9c3d5296d2d3fef37 168 Pfam PF03719 Ribosomal protein S5, C-terminal domain 89 159 2.1E-32 T 11-11-2016 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 AUP74_RS06910 0829f2bb415489a9c3d5296d2d3fef37 168 SUPERFAMILY SSF54211 81 161 1.09E-27 T 11-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold AUP74_RS06910 0829f2bb415489a9c3d5296d2d3fef37 168 SUPERFAMILY SSF54768 10 78 1.88E-23 T 11-11-2016 AUP74_RS06910 0829f2bb415489a9c3d5296d2d3fef37 168 Pfam PF00333 Ribosomal protein S5, N-terminal domain 13 76 3.7E-28 T 11-11-2016 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 AUP74_RS06910 0829f2bb415489a9c3d5296d2d3fef37 168 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 165 34.356 T 11-11-2016 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 AUP74_RS06910 0829f2bb415489a9c3d5296d2d3fef37 168 Gene3D G3DSA:3.30.230.10 79 161 6.9E-34 T 11-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AUP74_RS06910 0829f2bb415489a9c3d5296d2d3fef37 168 ProSitePatterns PS00585 Ribosomal protein S5 signature. 30 62 - T 11-11-2016 IPR018192 Ribosomal protein S5, N-terminal, conserved site AUP74_RS06910 0829f2bb415489a9c3d5296d2d3fef37 168 Gene3D G3DSA:3.30.160.20 11 74 4.8E-29 T 11-11-2016 IPR014720 Double-stranded RNA-binding domain AUP74_RS06910 0829f2bb415489a9c3d5296d2d3fef37 168 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 12 165 1.1E-67 T 11-11-2016 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 AUP74_RS08210 99652e63758896e9766e039eb70fb4ab 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 2.6E-37 T 11-11-2016 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS08210 99652e63758896e9766e039eb70fb4ab 89 Pfam PF00312 Ribosomal protein S15 8 88 7.8E-37 T 11-11-2016 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS08210 99652e63758896e9766e039eb70fb4ab 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 11 88 5.0E-24 T 11-11-2016 AUP74_RS08210 99652e63758896e9766e039eb70fb4ab 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 21.631 T 11-11-2016 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS08210 99652e63758896e9766e039eb70fb4ab 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 11-11-2016 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS08210 99652e63758896e9766e039eb70fb4ab 89 SMART SM01387 8 88 2.0E-50 T 11-11-2016 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS08210 99652e63758896e9766e039eb70fb4ab 89 SUPERFAMILY SSF47060 3 89 1.68E-34 T 11-11-2016 IPR009068 S15/NS1, RNA-binding AUP74_RS08210 99652e63758896e9766e039eb70fb4ab 89 Gene3D G3DSA:1.10.287.10 3 89 1.6E-38 T 11-11-2016 IPR009068 S15/NS1, RNA-binding AUP74_RS06795 1345e596045402b757e05e4af403eec1 123 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 123 4.8E-70 T 11-11-2016 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06795 1345e596045402b757e05e4af403eec1 123 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 11-11-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS06795 1345e596045402b757e05e4af403eec1 123 SUPERFAMILY SSF50249 3 123 3.94E-51 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS06795 1345e596045402b757e05e4af403eec1 123 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.207 T 11-11-2016 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06795 1345e596045402b757e05e4af403eec1 123 PIRSF PIRSF002133 1 123 7.1E-54 T 11-11-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS06795 1345e596045402b757e05e4af403eec1 123 Pfam PF00164 Ribosomal protein S12/S23 4 123 9.6E-43 T 11-11-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS06795 1345e596045402b757e05e4af403eec1 123 PRINTS PR01034 Ribosomal protein S12 signature 42 57 2.0E-59 T 11-11-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS06795 1345e596045402b757e05e4af403eec1 123 PRINTS PR01034 Ribosomal protein S12 signature 94 110 2.0E-59 T 11-11-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS06795 1345e596045402b757e05e4af403eec1 123 PRINTS PR01034 Ribosomal protein S12 signature 110 122 2.0E-59 T 11-11-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS06795 1345e596045402b757e05e4af403eec1 123 PRINTS PR01034 Ribosomal protein S12 signature 58 77 2.0E-59 T 11-11-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS06795 1345e596045402b757e05e4af403eec1 123 PRINTS PR01034 Ribosomal protein S12 signature 27 42 2.0E-59 T 11-11-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS06795 1345e596045402b757e05e4af403eec1 123 PRINTS PR01034 Ribosomal protein S12 signature 77 94 2.0E-59 T 11-11-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS06795 1345e596045402b757e05e4af403eec1 123 Gene3D G3DSA:2.40.50.140 1 123 8.5E-65 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS01535 a8233a0e271fef86818664eaaa43f397 316 PIRSF PIRSF005303 1 316 8.2E-79 T 11-11-2016 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 AUP74_RS01535 a8233a0e271fef86818664eaaa43f397 316 Pfam PF00586 AIR synthase related protein, N-terminal domain 29 137 6.9E-24 T 11-11-2016 IPR016188 PurM-like, N-terminal domain AUP74_RS01535 a8233a0e271fef86818664eaaa43f397 316 SUPERFAMILY SSF56042 140 294 1.64E-35 T 11-11-2016 IPR010918 AIR synthase-related protein, C-terminal domain AUP74_RS01535 a8233a0e271fef86818664eaaa43f397 316 Gene3D G3DSA:3.90.650.10 143 316 3.7E-43 T 11-11-2016 IPR010918 AIR synthase-related protein, C-terminal domain AUP74_RS01535 a8233a0e271fef86818664eaaa43f397 316 Pfam PF02769 AIR synthase related protein, C-terminal domain 149 274 8.4E-7 T 11-11-2016 IPR010918 AIR synthase-related protein, C-terminal domain AUP74_RS01535 a8233a0e271fef86818664eaaa43f397 316 Gene3D G3DSA:3.30.1330.10 2 140 4.1E-42 T 11-11-2016 IPR016188 PurM-like, N-terminal domain AUP74_RS01535 a8233a0e271fef86818664eaaa43f397 316 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 4 313 27.828 T 11-11-2016 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 AUP74_RS01535 a8233a0e271fef86818664eaaa43f397 316 SUPERFAMILY SSF55326 2 137 2.09E-33 T 11-11-2016 AUP74_RS01535 a8233a0e271fef86818664eaaa43f397 316 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 5 316 2.3E-89 T 11-11-2016 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 AUP74_RS05450 6330b74439b1daef8bab93683b6a5e90 276 SUPERFAMILY SSF54506 2 274 2.22E-53 T 11-11-2016 AUP74_RS05450 6330b74439b1daef8bab93683b6a5e90 276 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 3 276 39.076 T 11-11-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AUP74_RS05450 6330b74439b1daef8bab93683b6a5e90 276 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 66 80 - T 11-11-2016 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AUP74_RS05450 6330b74439b1daef8bab93683b6a5e90 276 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 4 274 1.9E-89 T 11-11-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AUP74_RS05450 6330b74439b1daef8bab93683b6a5e90 276 Gene3D G3DSA:3.10.310.10 123 264 4.2E-51 T 11-11-2016 AUP74_RS05450 6330b74439b1daef8bab93683b6a5e90 276 Pfam PF01678 Diaminopimelate epimerase 5 124 2.0E-31 T 11-11-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AUP74_RS05450 6330b74439b1daef8bab93683b6a5e90 276 Pfam PF01678 Diaminopimelate epimerase 154 268 2.0E-29 T 11-11-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AUP74_RS05450 6330b74439b1daef8bab93683b6a5e90 276 Gene3D G3DSA:3.10.310.10 3 122 1.7E-48 T 11-11-2016 AUP74_RS02530 07a550c2c333deccfa369738cec3e567 437 Pfam PF00875 DNA photolyase 3 171 3.3E-40 T 11-11-2016 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 AUP74_RS02530 07a550c2c333deccfa369738cec3e567 437 SUPERFAMILY SSF48173 208 433 4.58E-67 T 11-11-2016 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 AUP74_RS02530 07a550c2c333deccfa369738cec3e567 437 Pfam PF03441 FAD binding domain of DNA photolyase 289 433 3.3E-35 T 11-11-2016 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 AUP74_RS02530 07a550c2c333deccfa369738cec3e567 437 PRINTS PR00147 DNA photolyase signature 336 352 3.7E-6 T 11-11-2016 IPR002081 Cryptochrome/DNA photolyase class 1 AUP74_RS02530 07a550c2c333deccfa369738cec3e567 437 PRINTS PR00147 DNA photolyase signature 395 409 3.7E-6 T 11-11-2016 IPR002081 Cryptochrome/DNA photolyase class 1 AUP74_RS02530 07a550c2c333deccfa369738cec3e567 437 PRINTS PR00147 DNA photolyase signature 356 374 3.7E-6 T 11-11-2016 IPR002081 Cryptochrome/DNA photolyase class 1 AUP74_RS02530 07a550c2c333deccfa369738cec3e567 437 Gene3D G3DSA:1.10.579.10 298 433 2.8E-46 T 11-11-2016 AUP74_RS02530 07a550c2c333deccfa369738cec3e567 437 Gene3D G3DSA:1.25.40.80 148 297 5.1E-54 T 11-11-2016 AUP74_RS02530 07a550c2c333deccfa369738cec3e567 437 Gene3D G3DSA:3.40.50.620 2 147 8.8E-41 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS02530 07a550c2c333deccfa369738cec3e567 437 TIGRFAM TIGR02765 crypto_DASH: cryptochrome, DASH family 2 434 2.7E-148 T 11-11-2016 IPR014133 Cryptochrome DASH GO:0003913|GO:0006281 AUP74_RS02530 07a550c2c333deccfa369738cec3e567 437 SUPERFAMILY SSF52425 2 183 1.11E-48 T 11-11-2016 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 AUP74_RS12965 bad50363ec2de151b7feb3776e1f3fe7 227 SUPERFAMILY SSF46689 21 93 3.84E-16 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS12965 bad50363ec2de151b7feb3776e1f3fe7 227 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 77 1.4E-13 T 11-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AUP74_RS12965 bad50363ec2de151b7feb3776e1f3fe7 227 Gene3D G3DSA:1.10.357.10 16 206 3.6E-25 T 11-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 AUP74_RS12965 bad50363ec2de151b7feb3776e1f3fe7 227 ProSitePatterns PS01081 TetR-type HTH domain signature. 44 75 - T 11-11-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AUP74_RS12965 bad50363ec2de151b7feb3776e1f3fe7 227 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 45 9.6E-9 T 11-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AUP74_RS12965 bad50363ec2de151b7feb3776e1f3fe7 227 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 53 76 9.6E-9 T 11-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AUP74_RS09010 cdba463e937f381ac74981b7ae97613f 338 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 7 147 8.6E-39 T 11-11-2016 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 AUP74_RS09010 cdba463e937f381ac74981b7ae97613f 338 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 7 316 1.6E-92 T 11-11-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 AUP74_RS09010 cdba463e937f381ac74981b7ae97613f 338 Gene3D G3DSA:3.40.50.1370 143 303 3.5E-50 T 11-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AUP74_RS09010 cdba463e937f381ac74981b7ae97613f 338 Gene3D G3DSA:3.40.50.1370 4 142 9.4E-48 T 11-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AUP74_RS09010 cdba463e937f381ac74981b7ae97613f 338 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 266 275 6.3E-20 T 11-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AUP74_RS09010 cdba463e937f381ac74981b7ae97613f 338 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 51 70 6.3E-20 T 11-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AUP74_RS09010 cdba463e937f381ac74981b7ae97613f 338 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 6.3E-20 T 11-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AUP74_RS09010 cdba463e937f381ac74981b7ae97613f 338 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 281 304 6.3E-20 T 11-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AUP74_RS09010 cdba463e937f381ac74981b7ae97613f 338 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 51 58 - T 11-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AUP74_RS09010 cdba463e937f381ac74981b7ae97613f 338 PRINTS PR00101 Aspartate carbamoyltransferase signature 80 89 6.6E-30 T 11-11-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 AUP74_RS09010 cdba463e937f381ac74981b7ae97613f 338 PRINTS PR00101 Aspartate carbamoyltransferase signature 41 63 6.6E-30 T 11-11-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 AUP74_RS09010 cdba463e937f381ac74981b7ae97613f 338 PRINTS PR00101 Aspartate carbamoyltransferase signature 134 151 6.6E-30 T 11-11-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 AUP74_RS09010 cdba463e937f381ac74981b7ae97613f 338 PRINTS PR00101 Aspartate carbamoyltransferase signature 230 239 6.6E-30 T 11-11-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 AUP74_RS09010 cdba463e937f381ac74981b7ae97613f 338 PRINTS PR00101 Aspartate carbamoyltransferase signature 297 311 6.6E-30 T 11-11-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 AUP74_RS09010 cdba463e937f381ac74981b7ae97613f 338 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 160 314 1.1E-27 T 11-11-2016 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 AUP74_RS09010 cdba463e937f381ac74981b7ae97613f 338 SUPERFAMILY SSF53671 2 317 6.68E-87 T 11-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AUP74_RS08670 b9331d26ce4455b068d0c43778e3878b 351 SUPERFAMILY SSF51735 2 349 2.61E-86 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS08670 b9331d26ce4455b068d0c43778e3878b 351 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 4 351 1.3E-148 T 11-11-2016 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 AUP74_RS08670 b9331d26ce4455b068d0c43778e3878b 351 Gene3D G3DSA:3.40.50.720 1 191 1.8E-64 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS08670 b9331d26ce4455b068d0c43778e3878b 351 Gene3D G3DSA:3.90.25.10 192 349 5.7E-47 T 11-11-2016 AUP74_RS08670 b9331d26ce4455b068d0c43778e3878b 351 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 11-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AUP74_RS08670 b9331d26ce4455b068d0c43778e3878b 351 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 336 7.3E-92 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS13510 8240e026c8b1c08b98ff51379d2b0042 403 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 11-11-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AUP74_RS13510 8240e026c8b1c08b98ff51379d2b0042 403 Gene3D G3DSA:2.40.110.10 122 218 1.1E-38 T 11-11-2016 AUP74_RS13510 8240e026c8b1c08b98ff51379d2b0042 403 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 375 4.2E-41 T 11-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AUP74_RS13510 8240e026c8b1c08b98ff51379d2b0042 403 Gene3D G3DSA:1.20.140.10 219 382 1.6E-50 T 11-11-2016 AUP74_RS13510 8240e026c8b1c08b98ff51379d2b0042 403 SUPERFAMILY SSF56645 2 241 2.23E-78 T 11-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 AUP74_RS13510 8240e026c8b1c08b98ff51379d2b0042 403 SUPERFAMILY SSF47203 229 376 2.9E-39 T 11-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AUP74_RS13510 8240e026c8b1c08b98ff51379d2b0042 403 Gene3D G3DSA:1.10.540.10 3 119 3.7E-33 T 11-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 AUP74_RS13510 8240e026c8b1c08b98ff51379d2b0042 403 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 11-11-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AUP74_RS13510 8240e026c8b1c08b98ff51379d2b0042 403 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 8.6E-26 T 11-11-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 AUP74_RS13510 8240e026c8b1c08b98ff51379d2b0042 403 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 4 118 1.4E-30 T 11-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 AUP74_RS06080 977e5fccb50336561aa2c8fa7f507f7b 345 SUPERFAMILY SSF111369 42 257 9.81E-39 T 11-11-2016 AUP74_RS06080 977e5fccb50336561aa2c8fa7f507f7b 345 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 28 336 5.1E-73 T 11-11-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 AUP74_RS06080 977e5fccb50336561aa2c8fa7f507f7b 345 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 55 252 4.8E-27 T 11-11-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AUP74_RS06080 977e5fccb50336561aa2c8fa7f507f7b 345 Gene3D G3DSA:2.40.50.100 53 86 1.5E-12 T 11-11-2016 AUP74_RS06080 977e5fccb50336561aa2c8fa7f507f7b 345 Gene3D G3DSA:2.40.50.100 147 178 1.5E-12 T 11-11-2016 AUP74_RS05785 bcdf8e821de23d03d7533ad1cef4a306 268 ProSitePatterns PS00380 Rhodanese signature 1. 34 45 - T 11-11-2016 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 AUP74_RS05785 bcdf8e821de23d03d7533ad1cef4a306 268 Gene3D G3DSA:3.40.250.10 144 267 1.9E-32 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS05785 bcdf8e821de23d03d7533ad1cef4a306 268 SMART SM00450 147 264 1.1E-16 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS05785 bcdf8e821de23d03d7533ad1cef4a306 268 SMART SM00450 9 124 1.2E-21 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS05785 bcdf8e821de23d03d7533ad1cef4a306 268 SUPERFAMILY SSF52821 6 141 7.86E-37 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS05785 bcdf8e821de23d03d7533ad1cef4a306 268 SUPERFAMILY SSF52821 142 267 4.06E-29 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS05785 bcdf8e821de23d03d7533ad1cef4a306 268 Pfam PF00581 Rhodanese-like domain 11 120 1.5E-18 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS05785 bcdf8e821de23d03d7533ad1cef4a306 268 Pfam PF00581 Rhodanese-like domain 149 259 1.3E-14 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS05785 bcdf8e821de23d03d7533ad1cef4a306 268 Gene3D G3DSA:3.40.250.10 6 139 6.0E-38 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS07980 438f3378e7c92619d9d3d36365d1a9d0 378 Gene3D G3DSA:3.40.50.880 156 376 8.8E-82 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS07980 438f3378e7c92619d9d3d36365d1a9d0 378 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 5 378 48.144 T 11-11-2016 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 AUP74_RS07980 438f3378e7c92619d9d3d36365d1a9d0 378 PRINTS PR00096 Glutamine amidotransferase superfamily signature 264 275 6.8E-11 T 11-11-2016 AUP74_RS07980 438f3378e7c92619d9d3d36365d1a9d0 378 PRINTS PR00096 Glutamine amidotransferase superfamily signature 349 362 6.8E-11 T 11-11-2016 AUP74_RS07980 438f3378e7c92619d9d3d36365d1a9d0 378 PRINTS PR00096 Glutamine amidotransferase superfamily signature 236 245 6.8E-11 T 11-11-2016 AUP74_RS07980 438f3378e7c92619d9d3d36365d1a9d0 378 PRINTS PR00097 Anthranilate synthase component II signature 349 362 1.9E-5 T 11-11-2016 AUP74_RS07980 438f3378e7c92619d9d3d36365d1a9d0 378 PRINTS PR00097 Anthranilate synthase component II signature 236 245 1.9E-5 T 11-11-2016 AUP74_RS07980 438f3378e7c92619d9d3d36365d1a9d0 378 PRINTS PR00097 Anthranilate synthase component II signature 264 275 1.9E-5 T 11-11-2016 AUP74_RS07980 438f3378e7c92619d9d3d36365d1a9d0 378 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 7 375 3.4E-146 T 11-11-2016 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 AUP74_RS07980 438f3378e7c92619d9d3d36365d1a9d0 378 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 194 208 3.7E-39 T 11-11-2016 AUP74_RS07980 438f3378e7c92619d9d3d36365d1a9d0 378 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 264 280 3.7E-39 T 11-11-2016 AUP74_RS07980 438f3378e7c92619d9d3d36365d1a9d0 378 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 281 298 3.7E-39 T 11-11-2016 AUP74_RS07980 438f3378e7c92619d9d3d36365d1a9d0 378 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 306 317 3.7E-39 T 11-11-2016 AUP74_RS07980 438f3378e7c92619d9d3d36365d1a9d0 378 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 233 247 3.7E-39 T 11-11-2016 AUP74_RS07980 438f3378e7c92619d9d3d36365d1a9d0 378 SUPERFAMILY SSF52021 6 142 1.7E-54 T 11-11-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 AUP74_RS07980 438f3378e7c92619d9d3d36365d1a9d0 378 SMART SM01097 5 135 4.2E-86 T 11-11-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 AUP74_RS07980 438f3378e7c92619d9d3d36365d1a9d0 378 Pfam PF00117 Glutamine amidotransferase class-I 197 372 2.2E-48 T 11-11-2016 IPR017926 Glutamine amidotransferase AUP74_RS07980 438f3378e7c92619d9d3d36365d1a9d0 378 SUPERFAMILY SSF52317 155 377 1.83E-62 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS07980 438f3378e7c92619d9d3d36365d1a9d0 378 Gene3D G3DSA:3.50.30.20 6 144 3.2E-59 T 11-11-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 AUP74_RS07980 438f3378e7c92619d9d3d36365d1a9d0 378 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 7 134 2.8E-50 T 11-11-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 AUP74_RS03605 1c311f6d87f45863eb5b4f3f17e80c3a 393 SUPERFAMILY SSF47384 169 243 1.73E-9 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS03605 1c311f6d87f45863eb5b4f3f17e80c3a 393 Gene3D G3DSA:1.10.287.130 185 241 3.6E-8 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS03605 1c311f6d87f45863eb5b4f3f17e80c3a 393 Gene3D G3DSA:3.30.565.10 251 391 3.2E-22 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS03605 1c311f6d87f45863eb5b4f3f17e80c3a 393 PRINTS PR00344 Bacterial sensor protein C-terminal signature 322 336 1.5E-5 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS03605 1c311f6d87f45863eb5b4f3f17e80c3a 393 PRINTS PR00344 Bacterial sensor protein C-terminal signature 352 370 1.5E-5 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS03605 1c311f6d87f45863eb5b4f3f17e80c3a 393 SUPERFAMILY SSF55874 235 390 5.37E-23 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS03605 1c311f6d87f45863eb5b4f3f17e80c3a 393 SMART SM00387 287 393 1.6E-16 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS03605 1c311f6d87f45863eb5b4f3f17e80c3a 393 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 291 391 4.9E-14 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS03605 1c311f6d87f45863eb5b4f3f17e80c3a 393 Pfam PF00512 His Kinase A (phospho-acceptor) domain 187 243 3.2E-6 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS03605 1c311f6d87f45863eb5b4f3f17e80c3a 393 SMART SM00388 186 245 3.4E-6 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS13225 7fde7f322dca9eb79c28023f7d93ce03 93 Pfam PF04248 Domain of unknown function (DUF427) 1 87 5.0E-33 T 11-11-2016 IPR007361 Domain of unknown function DUF427 AUP74_RS06330 47eb77284a09ad9b27d972b5d8e8b16e 349 ProSitePatterns PS01016 Glycoprotease family signature. 96 116 - T 11-11-2016 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 AUP74_RS06330 47eb77284a09ad9b27d972b5d8e8b16e 349 Pfam PF00814 Glycoprotease family 24 312 4.5E-100 T 11-11-2016 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 AUP74_RS06330 47eb77284a09ad9b27d972b5d8e8b16e 349 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 311 1.6E-118 T 11-11-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 AUP74_RS06330 47eb77284a09ad9b27d972b5d8e8b16e 349 SUPERFAMILY SSF53067 3 123 2.94E-31 T 11-11-2016 AUP74_RS06330 47eb77284a09ad9b27d972b5d8e8b16e 349 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 3 318 6.3E-135 T 11-11-2016 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 AUP74_RS06330 47eb77284a09ad9b27d972b5d8e8b16e 349 Gene3D G3DSA:3.30.420.40 2 159 5.1E-47 T 11-11-2016 AUP74_RS06330 47eb77284a09ad9b27d972b5d8e8b16e 349 SUPERFAMILY SSF53067 101 314 1.53E-43 T 11-11-2016 AUP74_RS06330 47eb77284a09ad9b27d972b5d8e8b16e 349 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 336 63.643 T 11-11-2016 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 AUP74_RS06330 47eb77284a09ad9b27d972b5d8e8b16e 349 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 131 143 8.0E-51 T 11-11-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 AUP74_RS06330 47eb77284a09ad9b27d972b5d8e8b16e 349 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 154 175 8.0E-51 T 11-11-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 AUP74_RS06330 47eb77284a09ad9b27d972b5d8e8b16e 349 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 97 116 8.0E-51 T 11-11-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 AUP74_RS06330 47eb77284a09ad9b27d972b5d8e8b16e 349 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 76 96 8.0E-51 T 11-11-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 AUP74_RS06330 47eb77284a09ad9b27d972b5d8e8b16e 349 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 268 277 8.0E-51 T 11-11-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 AUP74_RS06330 47eb77284a09ad9b27d972b5d8e8b16e 349 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 8.0E-51 T 11-11-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 AUP74_RS06445 5deb9ec167c0c0129c4eb478fe368675 503 Pfam PF00425 chorismate binding enzyme 223 476 7.0E-97 T 11-11-2016 IPR015890 Chorismate-utilising enzyme, C-terminal AUP74_RS06445 5deb9ec167c0c0129c4eb478fe368675 503 Pfam PF04715 Anthranilate synthase component I, N terminal region 26 165 1.8E-35 T 11-11-2016 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058|GO:0016833 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AUP74_RS06445 5deb9ec167c0c0129c4eb478fe368675 503 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 26 484 5.9E-175 T 11-11-2016 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AUP74_RS06445 5deb9ec167c0c0129c4eb478fe368675 503 Gene3D G3DSA:3.60.120.10 13 487 3.7E-179 T 11-11-2016 IPR005801 ADC synthase GO:0009058 AUP74_RS06445 5deb9ec167c0c0129c4eb478fe368675 503 SUPERFAMILY SSF56322 14 483 8.24E-160 T 11-11-2016 IPR005801 ADC synthase GO:0009058 AUP74_RS06445 5deb9ec167c0c0129c4eb478fe368675 503 PRINTS PR00095 Anthranilate synthase component I signature 338 351 7.9E-26 T 11-11-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AUP74_RS06445 5deb9ec167c0c0129c4eb478fe368675 503 PRINTS PR00095 Anthranilate synthase component I signature 433 447 7.9E-26 T 11-11-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AUP74_RS06445 5deb9ec167c0c0129c4eb478fe368675 503 PRINTS PR00095 Anthranilate synthase component I signature 324 337 7.9E-26 T 11-11-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AUP74_RS06445 5deb9ec167c0c0129c4eb478fe368675 503 PRINTS PR00095 Anthranilate synthase component I signature 418 432 7.9E-26 T 11-11-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AUP74_RS16745 4f9121ce3533ef846e2bc7a1bc1d378e 461 SUPERFAMILY SSF53244 311 451 1.1E-42 T 11-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AUP74_RS16745 4f9121ce3533ef846e2bc7a1bc1d378e 461 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 8 451 34.264 T 11-11-2016 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AUP74_RS16745 4f9121ce3533ef846e2bc7a1bc1d378e 461 Pfam PF02875 Mur ligase family, glutamate ligase domain 314 374 8.1E-8 T 11-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AUP74_RS16745 4f9121ce3533ef846e2bc7a1bc1d378e 461 Gene3D G3DSA:3.40.50.720 9 97 2.3E-19 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS16745 4f9121ce3533ef846e2bc7a1bc1d378e 461 Pfam PF08245 Mur ligase middle domain 119 291 1.7E-28 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AUP74_RS16745 4f9121ce3533ef846e2bc7a1bc1d378e 461 SUPERFAMILY SSF53623 112 309 1.83E-53 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AUP74_RS16745 4f9121ce3533ef846e2bc7a1bc1d378e 461 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 11 449 3.5E-125 T 11-11-2016 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AUP74_RS16745 4f9121ce3533ef846e2bc7a1bc1d378e 461 Gene3D G3DSA:3.40.1190.10 98 311 8.3E-66 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AUP74_RS16745 4f9121ce3533ef846e2bc7a1bc1d378e 461 Gene3D G3DSA:3.90.190.20 314 448 2.2E-45 T 11-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AUP74_RS16745 4f9121ce3533ef846e2bc7a1bc1d378e 461 SUPERFAMILY SSF51984 11 98 7.98E-16 T 11-11-2016 AUP74_RS07690 83db6e42146adcede1137858062da85a 747 SMART SM00062 78 296 4.0E-26 T 11-11-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AUP74_RS07690 83db6e42146adcede1137858062da85a 747 SMART SM00062 304 529 1.6E-29 T 11-11-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AUP74_RS07690 83db6e42146adcede1137858062da85a 747 Gene3D G3DSA:3.40.190.10 97 152 8.5E-17 T 11-11-2016 AUP74_RS07690 83db6e42146adcede1137858062da85a 747 Gene3D G3DSA:3.40.190.10 255 284 8.5E-17 T 11-11-2016 AUP74_RS07690 83db6e42146adcede1137858062da85a 747 SUPERFAMILY SSF53850 76 284 1.9E-32 T 11-11-2016 AUP74_RS07690 83db6e42146adcede1137858062da85a 747 SUPERFAMILY SSF53955 547 715 4.97E-41 T 11-11-2016 IPR023346 Lysozyme-like domain AUP74_RS07690 83db6e42146adcede1137858062da85a 747 Gene3D G3DSA:3.40.190.10 381 469 1.0E-10 T 11-11-2016 AUP74_RS07690 83db6e42146adcede1137858062da85a 747 Gene3D G3DSA:3.40.190.10 153 251 5.8E-10 T 11-11-2016 AUP74_RS07690 83db6e42146adcede1137858062da85a 747 SUPERFAMILY SSF53850 296 529 5.27E-37 T 11-11-2016 AUP74_RS07690 83db6e42146adcede1137858062da85a 747 Gene3D G3DSA:3.40.190.10 301 380 8.0E-19 T 11-11-2016 AUP74_RS07690 83db6e42146adcede1137858062da85a 747 Gene3D G3DSA:3.40.190.10 488 528 8.0E-19 T 11-11-2016 AUP74_RS07690 83db6e42146adcede1137858062da85a 747 Gene3D G3DSA:1.10.530.10 546 716 5.9E-43 T 11-11-2016 AUP74_RS07690 83db6e42146adcede1137858062da85a 747 Pfam PF01464 Transglycosylase SLT domain 553 661 5.4E-25 T 11-11-2016 IPR008258 Transglycosylase SLT domain 1 AUP74_RS07690 83db6e42146adcede1137858062da85a 747 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 310 527 3.6E-32 T 11-11-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AUP74_RS07690 83db6e42146adcede1137858062da85a 747 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 101 284 7.1E-30 T 11-11-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AUP74_RS09485 5b5fc1159e4a2421403b89f8f315f81a 819 SUPERFAMILY SSF55008 93 162 7.98E-18 T 11-11-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 AUP74_RS09485 5b5fc1159e4a2421403b89f8f315f81a 819 Gene3D G3DSA:3.30.70.100 96 162 1.7E-18 T 11-11-2016 AUP74_RS09485 5b5fc1159e4a2421403b89f8f315f81a 819 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 362 376 4.3E-17 T 11-11-2016 AUP74_RS09485 5b5fc1159e4a2421403b89f8f315f81a 819 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 510 524 4.3E-17 T 11-11-2016 AUP74_RS09485 5b5fc1159e4a2421403b89f8f315f81a 819 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 718 730 4.3E-17 T 11-11-2016 AUP74_RS09485 5b5fc1159e4a2421403b89f8f315f81a 819 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 695 714 4.3E-17 T 11-11-2016 AUP74_RS09485 5b5fc1159e4a2421403b89f8f315f81a 819 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 642 652 4.3E-17 T 11-11-2016 AUP74_RS09485 5b5fc1159e4a2421403b89f8f315f81a 819 Pfam PF12156 Putative metal-binding domain of cation transport ATPase 5 86 2.8E-24 T 11-11-2016 IPR021993 Putative metal-binding domain of cation transport ATPase AUP74_RS09485 5b5fc1159e4a2421403b89f8f315f81a 819 Pfam PF00122 E1-E2 ATPase 284 501 8.1E-56 T 11-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 AUP74_RS09485 5b5fc1159e4a2421403b89f8f315f81a 819 ProSitePatterns PS01229 Hypothetical cof family signature 2. 695 717 - T 11-11-2016 AUP74_RS09485 5b5fc1159e4a2421403b89f8f315f81a 819 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 278 798 5.9E-110 T 11-11-2016 AUP74_RS09485 5b5fc1159e4a2421403b89f8f315f81a 819 SUPERFAMILY SSF81653 315 412 4.45E-24 T 11-11-2016 AUP74_RS09485 5b5fc1159e4a2421403b89f8f315f81a 819 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 286 774 2.5E-63 T 11-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AUP74_RS09485 5b5fc1159e4a2421403b89f8f315f81a 819 SUPERFAMILY SSF56784 565 795 2.95E-44 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS09485 5b5fc1159e4a2421403b89f8f315f81a 819 SUPERFAMILY SSF56784 509 528 2.95E-44 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS09485 5b5fc1159e4a2421403b89f8f315f81a 819 Gene3D G3DSA:2.70.150.10 277 413 2.3E-24 T 11-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 AUP74_RS09485 5b5fc1159e4a2421403b89f8f315f81a 819 Pfam PF00702 haloacid dehalogenase-like hydrolase 509 709 7.2E-29 T 11-11-2016 AUP74_RS09485 5b5fc1159e4a2421403b89f8f315f81a 819 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 251 797 2.3E-151 T 11-11-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AUP74_RS09485 5b5fc1159e4a2421403b89f8f315f81a 819 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 512 518 - T 11-11-2016 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 AUP74_RS09485 5b5fc1159e4a2421403b89f8f315f81a 819 Pfam PF00403 Heavy-metal-associated domain 101 155 2.3E-9 T 11-11-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 AUP74_RS09485 5b5fc1159e4a2421403b89f8f315f81a 819 SUPERFAMILY SSF81665 412 503 5.75E-7 T 11-11-2016 AUP74_RS09485 5b5fc1159e4a2421403b89f8f315f81a 819 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 233 797 3.6E-146 T 11-11-2016 AUP74_RS09485 5b5fc1159e4a2421403b89f8f315f81a 819 Gene3D G3DSA:3.40.50.1000 484 526 3.7E-45 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS09485 5b5fc1159e4a2421403b89f8f315f81a 819 Gene3D G3DSA:3.40.50.1000 615 764 3.7E-45 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS02095 f0397e1c8cf5e8591013ad77f8209bd3 753 SUPERFAMILY SSF161098 519 734 5.23E-54 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AUP74_RS02095 f0397e1c8cf5e8591013ad77f8209bd3 753 SUPERFAMILY SSF160964 422 480 7.59E-6 T 11-11-2016 AUP74_RS02095 f0397e1c8cf5e8591013ad77f8209bd3 753 PRINTS PR00181 Maltose binding protein signature 132 151 1.2E-5 T 11-11-2016 IPR006060 Maltose binding protein GO:0005363|GO:0015768 AUP74_RS02095 f0397e1c8cf5e8591013ad77f8209bd3 753 PRINTS PR00181 Maltose binding protein signature 232 251 1.2E-5 T 11-11-2016 IPR006060 Maltose binding protein GO:0005363|GO:0015768 AUP74_RS02095 f0397e1c8cf5e8591013ad77f8209bd3 753 PRINTS PR00181 Maltose binding protein signature 297 318 1.2E-5 T 11-11-2016 IPR006060 Maltose binding protein GO:0005363|GO:0015768 AUP74_RS02095 f0397e1c8cf5e8591013ad77f8209bd3 753 PRINTS PR00181 Maltose binding protein signature 356 375 1.2E-5 T 11-11-2016 IPR006060 Maltose binding protein GO:0005363|GO:0015768 AUP74_RS02095 f0397e1c8cf5e8591013ad77f8209bd3 753 PRINTS PR00181 Maltose binding protein signature 69 87 1.2E-5 T 11-11-2016 IPR006060 Maltose binding protein GO:0005363|GO:0015768 AUP74_RS02095 f0397e1c8cf5e8591013ad77f8209bd3 753 Pfam PF13416 Bacterial extracellular solute-binding protein 45 340 1.7E-29 T 11-11-2016 AUP74_RS02095 f0397e1c8cf5e8591013ad77f8209bd3 753 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 541 741 6.6E-23 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AUP74_RS02095 f0397e1c8cf5e8591013ad77f8209bd3 753 SUPERFAMILY SSF53850 27 393 4.12E-73 T 11-11-2016 AUP74_RS02095 f0397e1c8cf5e8591013ad77f8209bd3 753 Gene3D G3DSA:3.40.190.10 154 327 2.6E-37 T 11-11-2016 AUP74_RS02095 f0397e1c8cf5e8591013ad77f8209bd3 753 Gene3D G3DSA:1.20.58.370 444 478 8.1E-6 T 11-11-2016 AUP74_RS02095 f0397e1c8cf5e8591013ad77f8209bd3 753 Gene3D G3DSA:3.40.190.10 34 153 9.5E-10 T 11-11-2016 AUP74_RS02095 f0397e1c8cf5e8591013ad77f8209bd3 753 Gene3D G3DSA:1.10.3720.10 520 742 1.1E-58 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AUP74_RS05095 f296d8fc61858a295e8031904739c506 335 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 79 332 4.5E-40 T 11-11-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 AUP74_RS05095 f296d8fc61858a295e8031904739c506 335 Gene3D G3DSA:3.90.850.10 65 269 3.8E-40 T 11-11-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 AUP74_RS05095 f296d8fc61858a295e8031904739c506 335 Gene3D G3DSA:3.90.850.10 305 315 3.8E-40 T 11-11-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 AUP74_RS05095 f296d8fc61858a295e8031904739c506 335 SUPERFAMILY SSF56529 75 332 3.27E-56 T 11-11-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 AUP74_RS01795 82fefb23fd255eeb531b1af9c430667e 691 SUPERFAMILY SSF143724 107 310 2.94E-53 T 11-11-2016 AUP74_RS01795 82fefb23fd255eeb531b1af9c430667e 691 Gene3D G3DSA:3.30.870.10 318 495 6.1E-61 T 11-11-2016 AUP74_RS01795 82fefb23fd255eeb531b1af9c430667e 691 Gene3D G3DSA:3.30.870.10 496 676 3.3E-60 T 11-11-2016 AUP74_RS01795 82fefb23fd255eeb531b1af9c430667e 691 Pfam PF13090 Polyphosphate kinase C-terminal domain 327 670 2.5E-132 T 11-11-2016 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 AUP74_RS01795 82fefb23fd255eeb531b1af9c430667e 691 Gene3D G3DSA:3.30.1840.10 106 301 4.0E-48 T 11-11-2016 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 AUP74_RS01795 82fefb23fd255eeb531b1af9c430667e 691 SUPERFAMILY SSF56024 315 487 1.6E-47 T 11-11-2016 AUP74_RS01795 82fefb23fd255eeb531b1af9c430667e 691 Pfam PF02503 Polyphosphate kinase middle domain 119 319 2.9E-44 T 11-11-2016 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 AUP74_RS01795 82fefb23fd255eeb531b1af9c430667e 691 Pfam PF13089 Polyphosphate kinase N-terminal domain 9 110 1.6E-30 T 11-11-2016 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 AUP74_RS01795 82fefb23fd255eeb531b1af9c430667e 691 SUPERFAMILY SSF56024 498 675 3.81E-57 T 11-11-2016 AUP74_RS01795 82fefb23fd255eeb531b1af9c430667e 691 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 9 671 1.8E-221 T 11-11-2016 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 AUP74_RS01795 82fefb23fd255eeb531b1af9c430667e 691 SUPERFAMILY SSF140356 4 104 8.76E-29 T 11-11-2016 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 AUP74_RS01795 82fefb23fd255eeb531b1af9c430667e 691 PIRSF PIRSF015589 1 689 1.2E-228 T 11-11-2016 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 AUP74_RS14755 fb9468486555c438701f69c5ac1adc89 647 Pfam PF02719 Polysaccharide biosynthesis protein 277 570 2.9E-123 T 11-11-2016 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain AUP74_RS14755 fb9468486555c438701f69c5ac1adc89 647 Gene3D G3DSA:3.90.25.10 462 533 8.3E-9 T 11-11-2016 AUP74_RS14755 fb9468486555c438701f69c5ac1adc89 647 Pfam PF13727 CoA-binding domain 62 232 8.5E-11 T 11-11-2016 AUP74_RS14755 fb9468486555c438701f69c5ac1adc89 647 SUPERFAMILY SSF53335 104 335 1.23E-18 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS14755 fb9468486555c438701f69c5ac1adc89 647 Gene3D G3DSA:3.40.50.720 276 461 2.7E-45 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS14755 fb9468486555c438701f69c5ac1adc89 647 Gene3D G3DSA:3.40.50.720 137 220 4.8E-14 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS14755 fb9468486555c438701f69c5ac1adc89 647 SUPERFAMILY SSF51735 274 532 5.29E-57 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS06140 5bbdd98466d194f1d22c6f98d31b3b5a 284 SUPERFAMILY SSF47226 161 273 9.89E-7 T 11-11-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 AUP74_RS06140 5bbdd98466d194f1d22c6f98d31b3b5a 284 Gene3D G3DSA:1.20.120.160 161 272 5.5E-4 T 11-11-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 AUP74_RS02840 d408d472919ebb3f92f1cf7f2d7c18c8 240 Pfam PF04402 Protein of unknown function (DUF541) 42 214 2.2E-19 T 11-11-2016 IPR007497 Protein of unknown function DUF541 AUP74_RS02840 d408d472919ebb3f92f1cf7f2d7c18c8 240 PIRSF PIRSF029033 1 240 4.3E-103 T 11-11-2016 IPR016907 Uncharacterised conserved protein UCP029033, periplasmic protein AUP74_RS12225 257d69dd4943332138fda8cf29550de2 190 SUPERFAMILY SSF51197 4 187 2.95E-53 T 11-11-2016 AUP74_RS12225 257d69dd4943332138fda8cf29550de2 190 Gene3D G3DSA:2.60.120.590 8 186 5.1E-34 T 11-11-2016 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like AUP74_RS12225 257d69dd4943332138fda8cf29550de2 190 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 9 184 2.9E-24 T 11-11-2016 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like AUP74_RS08020 506de77ad3e18d83fa43172f0b1bde87 312 Gene3D G3DSA:3.20.20.190 31 288 2.7E-57 T 11-11-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 AUP74_RS08020 506de77ad3e18d83fa43172f0b1bde87 312 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 46 279 2.0E-28 T 11-11-2016 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 AUP74_RS08020 506de77ad3e18d83fa43172f0b1bde87 312 SUPERFAMILY SSF51695 33 285 8.37E-54 T 11-11-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 AUP74_RS11325 2caea93749e1372257a415897d6fd558 136 TIGRFAM TIGR01244 TIGR01244: TIGR01244 family protein 3 131 1.2E-28 T 11-11-2016 IPR005939 Beta-lactamase hydrolase-like GO:0016787 AUP74_RS11325 2caea93749e1372257a415897d6fd558 136 Pfam PF04273 Putative phosphatase (DUF442) 3 103 3.9E-22 T 11-11-2016 IPR005939 Beta-lactamase hydrolase-like GO:0016787 AUP74_RS11325 2caea93749e1372257a415897d6fd558 136 Gene3D G3DSA:3.90.190.10 1 131 1.5E-33 T 11-11-2016 IPR029021 Protein-tyrosine phosphatase-like AUP74_RS05660 f7750a5525a844dcfd7e58b50c969376 254 Pfam PF02602 Uroporphyrinogen-III synthase HemD 21 245 1.1E-39 T 11-11-2016 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AUP74_RS05660 f7750a5525a844dcfd7e58b50c969376 254 Gene3D G3DSA:3.40.50.10090 1 122 7.8E-21 T 11-11-2016 AUP74_RS05660 f7750a5525a844dcfd7e58b50c969376 254 Gene3D G3DSA:3.40.50.10090 128 252 3.2E-12 T 11-11-2016 AUP74_RS05660 f7750a5525a844dcfd7e58b50c969376 254 SUPERFAMILY SSF69618 3 248 1.2E-55 T 11-11-2016 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AUP74_RS01470 e0718540e736c45da5515afd23c0e349 338 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 89 100 - T 11-11-2016 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AUP74_RS01470 e0718540e736c45da5515afd23c0e349 338 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 278 306 - T 11-11-2016 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AUP74_RS01470 e0718540e736c45da5515afd23c0e349 338 Gene3D G3DSA:3.30.470.20 111 129 9.1E-39 T 11-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 AUP74_RS01470 e0718540e736c45da5515afd23c0e349 338 Gene3D G3DSA:3.30.470.20 203 335 9.1E-39 T 11-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 AUP74_RS01470 e0718540e736c45da5515afd23c0e349 338 Gene3D G3DSA:3.30.1490.20 152 202 2.1E-15 T 11-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 AUP74_RS01470 e0718540e736c45da5515afd23c0e349 338 PIRSF PIRSF039102 8 338 1.9E-70 T 11-11-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AUP74_RS01470 e0718540e736c45da5515afd23c0e349 338 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 9 336 31.07 T 11-11-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AUP74_RS01470 e0718540e736c45da5515afd23c0e349 338 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 12 335 8.4E-87 T 11-11-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AUP74_RS01470 e0718540e736c45da5515afd23c0e349 338 Pfam PF01820 D-ala D-ala ligase N-terminus 12 112 1.0E-15 T 11-11-2016 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AUP74_RS01470 e0718540e736c45da5515afd23c0e349 338 Pfam PF07478 D-ala D-ala ligase C-terminus 131 332 2.0E-50 T 11-11-2016 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AUP74_RS01470 e0718540e736c45da5515afd23c0e349 338 Gene3D G3DSA:3.40.50.20 12 109 2.2E-16 T 11-11-2016 IPR016185 Pre-ATP-grasp domain AUP74_RS01470 e0718540e736c45da5515afd23c0e349 338 SUPERFAMILY SSF52440 11 121 1.06E-22 T 11-11-2016 IPR016185 Pre-ATP-grasp domain AUP74_RS01470 e0718540e736c45da5515afd23c0e349 338 SUPERFAMILY SSF56059 122 330 1.26E-40 T 11-11-2016 AUP74_RS05800 b0a41e3134321a6a1d72b9af0b4c8757 370 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 197 208 - T 11-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AUP74_RS05800 b0a41e3134321a6a1d72b9af0b4c8757 370 Gene3D G3DSA:3.30.70.20 194 262 5.3E-6 T 11-11-2016 AUP74_RS05800 b0a41e3134321a6a1d72b9af0b4c8757 370 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 13 352 8.3E-147 T 11-11-2016 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 AUP74_RS05800 b0a41e3134321a6a1d72b9af0b4c8757 370 Pfam PF08331 Domain of unknown function (DUF1730) 61 143 2.5E-19 T 11-11-2016 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 AUP74_RS05800 b0a41e3134321a6a1d72b9af0b4c8757 370 SUPERFAMILY SSF46548 142 260 2.98E-16 T 11-11-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 AUP74_RS05800 b0a41e3134321a6a1d72b9af0b4c8757 370 Pfam PF13484 4Fe-4S double cluster binding domain 196 260 1.1E-18 T 11-11-2016 AUP74_RS05800 b0a41e3134321a6a1d72b9af0b4c8757 370 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 6 319 48.918 T 11-11-2016 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 AUP74_RS08435 94caf3bb73de8973537824f54dd6f5ed 632 SUPERFAMILY SSF56601 253 608 1.24E-95 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS08435 94caf3bb73de8973537824f54dd6f5ed 632 SUPERFAMILY SSF56519 56 251 2.22E-49 T 11-11-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 AUP74_RS08435 94caf3bb73de8973537824f54dd6f5ed 632 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 20 608 2.2E-231 T 11-11-2016 IPR017790 Penicillin-binding protein 2 GO:0016020 AUP74_RS08435 94caf3bb73de8973537824f54dd6f5ed 632 Pfam PF03717 Penicillin-binding Protein dimerisation domain 65 238 1.1E-43 T 11-11-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 AUP74_RS08435 94caf3bb73de8973537824f54dd6f5ed 632 Gene3D G3DSA:3.90.1310.10 130 251 2.6E-35 T 11-11-2016 AUP74_RS08435 94caf3bb73de8973537824f54dd6f5ed 632 Pfam PF00905 Penicillin binding protein transpeptidase domain 270 603 2.0E-72 T 11-11-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 AUP74_RS08435 94caf3bb73de8973537824f54dd6f5ed 632 Gene3D G3DSA:3.40.710.10 253 609 2.2E-105 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS12960 b31796faae4509aed8949ced3c24f4e0 300 SUPERFAMILY SSF56784 158 283 1.67E-5 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS12960 b31796faae4509aed8949ced3c24f4e0 300 Pfam PF06189 5'-nucleotidase 37 296 5.6E-113 T 11-11-2016 IPR010394 5-nucleotidase GO:0000166|GO:0000287|GO:0005737|GO:0008253|GO:0009117 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|Reactome: R-HSA-74259 AUP74_RS07200 69818e29b30f8c6b81ee2decf2ca9cee 1024 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 1.6E-72 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS07200 69818e29b30f8c6b81ee2decf2ca9cee 1024 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.6E-72 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS07200 69818e29b30f8c6b81ee2decf2ca9cee 1024 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 1.6E-72 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS07200 69818e29b30f8c6b81ee2decf2ca9cee 1024 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 1.6E-72 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS07200 69818e29b30f8c6b81ee2decf2ca9cee 1024 PRINTS PR00702 Acriflavin resistance protein family signature 543 560 1.6E-72 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS07200 69818e29b30f8c6b81ee2decf2ca9cee 1024 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.6E-72 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS07200 69818e29b30f8c6b81ee2decf2ca9cee 1024 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 1.6E-72 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS07200 69818e29b30f8c6b81ee2decf2ca9cee 1024 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 1.6E-72 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS07200 69818e29b30f8c6b81ee2decf2ca9cee 1024 PRINTS PR00702 Acriflavin resistance protein family signature 610 624 1.6E-72 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS07200 69818e29b30f8c6b81ee2decf2ca9cee 1024 SUPERFAMILY SSF82714 183 265 1.14E-15 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS07200 69818e29b30f8c6b81ee2decf2ca9cee 1024 SUPERFAMILY SSF82693 556 656 4.71E-14 T 11-11-2016 AUP74_RS07200 69818e29b30f8c6b81ee2decf2ca9cee 1024 SUPERFAMILY SSF82866 289 490 1.83E-49 T 11-11-2016 AUP74_RS07200 69818e29b30f8c6b81ee2decf2ca9cee 1024 Gene3D G3DSA:3.30.70.1430 42 141 1.6E-21 T 11-11-2016 AUP74_RS07200 69818e29b30f8c6b81ee2decf2ca9cee 1024 SUPERFAMILY SSF82866 790 1012 9.42E-47 T 11-11-2016 AUP74_RS07200 69818e29b30f8c6b81ee2decf2ca9cee 1024 SUPERFAMILY SSF82714 706 792 2.35E-16 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS07200 69818e29b30f8c6b81ee2decf2ca9cee 1024 SUPERFAMILY SSF82693 267 324 1.12E-18 T 11-11-2016 AUP74_RS07200 69818e29b30f8c6b81ee2decf2ca9cee 1024 SUPERFAMILY SSF82693 137 181 1.12E-18 T 11-11-2016 AUP74_RS07200 69818e29b30f8c6b81ee2decf2ca9cee 1024 Gene3D G3DSA:3.30.2090.10 183 268 5.8E-18 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS07200 69818e29b30f8c6b81ee2decf2ca9cee 1024 Gene3D G3DSA:3.30.2090.10 705 794 6.6E-17 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS07200 69818e29b30f8c6b81ee2decf2ca9cee 1024 SUPERFAMILY SSF82693 42 128 1.15E-19 T 11-11-2016 AUP74_RS07200 69818e29b30f8c6b81ee2decf2ca9cee 1024 Pfam PF00873 AcrB/AcrD/AcrF family 4 1009 1.4E-257 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS07200 69818e29b30f8c6b81ee2decf2ca9cee 1024 Gene3D G3DSA:3.30.70.1430 559 656 7.1E-12 T 11-11-2016 AUP74_RS07200 69818e29b30f8c6b81ee2decf2ca9cee 1024 Gene3D G3DSA:1.10.3850.10 798 1012 5.6E-57 T 11-11-2016 AUP74_RS07200 69818e29b30f8c6b81ee2decf2ca9cee 1024 Gene3D G3DSA:1.20.1640.10 285 497 7.9E-59 T 11-11-2016 AUP74_RS08995 41e3063db651aa2fd52876becd2eeb92 293 Pfam PF04321 RmlD substrate binding domain 1 290 4.0E-60 T 11-11-2016 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581 AUP74_RS08995 41e3063db651aa2fd52876becd2eeb92 293 SUPERFAMILY SSF51735 1 275 2.16E-68 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS08995 41e3063db651aa2fd52876becd2eeb92 293 Gene3D G3DSA:3.40.50.720 1 241 4.6E-47 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS04350 bc24fc5dd9e1acc740ebe24ca88f6659 371 SUPERFAMILY SSF52518 29 359 5.34E-92 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS04350 bc24fc5dd9e1acc740ebe24ca88f6659 371 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 16 358 2.4E-132 T 11-11-2016 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 AUP74_RS04350 bc24fc5dd9e1acc740ebe24ca88f6659 371 Pfam PF00676 Dehydrogenase E1 component 44 334 3.7E-75 T 11-11-2016 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 AUP74_RS04350 bc24fc5dd9e1acc740ebe24ca88f6659 371 Gene3D G3DSA:3.40.50.970 10 358 4.7E-115 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS13750 44396d47f182f0fbf1ab8ff98690ca9d 206 Gene3D G3DSA:1.10.10.10 145 205 7.1E-17 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS13750 44396d47f182f0fbf1ab8ff98690ca9d 206 SUPERFAMILY SSF88659 119 205 4.36E-14 T 11-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS13750 44396d47f182f0fbf1ab8ff98690ca9d 206 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 39 204 5.9E-29 T 11-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS13750 44396d47f182f0fbf1ab8ff98690ca9d 206 SUPERFAMILY SSF88946 20 131 1.16E-24 T 11-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS13750 44396d47f182f0fbf1ab8ff98690ca9d 206 Pfam PF08281 Sigma-70, region 4 149 200 7.0E-15 T 11-11-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS13750 44396d47f182f0fbf1ab8ff98690ca9d 206 Pfam PF04542 Sigma-70 region 2 43 115 1.7E-18 T 11-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS13750 44396d47f182f0fbf1ab8ff98690ca9d 206 Gene3D G3DSA:1.10.1740.10 21 136 2.4E-23 T 11-11-2016 AUP74_RS14790 069f318777a92a18a17a67e03d012c52 102 Pfam PF00216 Bacterial DNA-binding protein 1 91 1.7E-29 T 11-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 AUP74_RS14790 069f318777a92a18a17a67e03d012c52 102 SMART SM00411 1 91 6.0E-44 T 11-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 AUP74_RS14790 069f318777a92a18a17a67e03d012c52 102 Gene3D G3DSA:4.10.520.10 1 92 9.4E-35 T 11-11-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 AUP74_RS14790 069f318777a92a18a17a67e03d012c52 102 Hamap MF_00381 Integration host factor subunit beta [ihfB]. 1 94 29.117 T 11-11-2016 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 AUP74_RS14790 069f318777a92a18a17a67e03d012c52 102 SUPERFAMILY SSF47729 1 91 6.33E-31 T 11-11-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 AUP74_RS14790 069f318777a92a18a17a67e03d012c52 102 TIGRFAM TIGR00988 hip: integration host factor, beta subunit 1 92 2.3E-46 T 11-11-2016 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 AUP74_RS14790 069f318777a92a18a17a67e03d012c52 102 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 6.8E-19 T 11-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 AUP74_RS14790 069f318777a92a18a17a67e03d012c52 102 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 6.8E-19 T 11-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 AUP74_RS14790 069f318777a92a18a17a67e03d012c52 102 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 6.8E-19 T 11-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 AUP74_RS14790 069f318777a92a18a17a67e03d012c52 102 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 11-11-2016 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 AUP74_RS00085 c7e89820ec82e0dda14fd3cc3b773ff9 266 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 21 257 8.1E-53 T 11-11-2016 IPR007221 Rod shape-determining protein MreC GO:0008360 AUP74_RS00085 c7e89820ec82e0dda14fd3cc3b773ff9 266 Pfam PF04085 rod shape-determining protein MreC 109 253 1.2E-35 T 11-11-2016 IPR007221 Rod shape-determining protein MreC GO:0008360 AUP74_RS00085 c7e89820ec82e0dda14fd3cc3b773ff9 266 PIRSF PIRSF038471 1 264 9.8E-65 T 11-11-2016 IPR007221 Rod shape-determining protein MreC GO:0008360 AUP74_RS08365 dde0d99411e09308fd86c1ba2165aa0b 463 Gene3D G3DSA:3.40.1190.10 93 318 3.4E-88 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AUP74_RS08365 dde0d99411e09308fd86c1ba2165aa0b 463 Pfam PF01225 Mur ligase family, catalytic domain 2 95 1.4E-17 T 11-11-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 AUP74_RS08365 dde0d99411e09308fd86c1ba2165aa0b 463 Gene3D G3DSA:3.90.190.20 319 455 4.0E-31 T 11-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AUP74_RS08365 dde0d99411e09308fd86c1ba2165aa0b 463 Gene3D G3DSA:3.40.50.720 1 90 1.7E-40 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS08365 dde0d99411e09308fd86c1ba2165aa0b 463 Pfam PF02875 Mur ligase family, glutamate ligase domain 317 365 2.0E-10 T 11-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AUP74_RS08365 dde0d99411e09308fd86c1ba2165aa0b 463 SUPERFAMILY SSF53244 316 453 1.16E-37 T 11-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AUP74_RS08365 dde0d99411e09308fd86c1ba2165aa0b 463 SUPERFAMILY SSF51984 1 90 2.75E-23 T 11-11-2016 AUP74_RS08365 dde0d99411e09308fd86c1ba2165aa0b 463 TIGRFAM TIGR01081 mpl: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 2 454 2.4E-209 T 11-11-2016 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 AUP74_RS08365 dde0d99411e09308fd86c1ba2165aa0b 463 Pfam PF08245 Mur ligase middle domain 108 297 7.4E-22 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AUP74_RS08365 dde0d99411e09308fd86c1ba2165aa0b 463 Hamap MF_02020 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase [mpl]. 1 455 58.6 T 11-11-2016 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 AUP74_RS08365 dde0d99411e09308fd86c1ba2165aa0b 463 SUPERFAMILY SSF53623 95 314 9.55E-53 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AUP74_RS11210 ab1abb750dade373dfe4b81d0ebbd391 429 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 10 413 2.6E-206 T 11-11-2016 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 AUP74_RS11210 ab1abb750dade373dfe4b81d0ebbd391 429 SMART SM00382 114 266 4.1E-11 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS11210 ab1abb750dade373dfe4b81d0ebbd391 429 Gene3D G3DSA:3.40.50.300 65 256 8.4E-51 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11210 ab1abb750dade373dfe4b81d0ebbd391 429 Gene3D G3DSA:3.40.50.300 296 312 8.4E-51 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11210 ab1abb750dade373dfe4b81d0ebbd391 429 Pfam PF07724 AAA domain (Cdc48 subfamily) 115 312 1.6E-48 T 11-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 AUP74_RS11210 ab1abb750dade373dfe4b81d0ebbd391 429 SUPERFAMILY SSF57716 14 49 9.98E-12 T 11-11-2016 AUP74_RS11210 ab1abb750dade373dfe4b81d0ebbd391 429 SMART SM01086 319 414 1.8E-34 T 11-11-2016 IPR019489 Clp ATPase, C-terminal AUP74_RS11210 ab1abb750dade373dfe4b81d0ebbd391 429 Gene3D G3DSA:1.10.8.60 318 417 1.5E-38 T 11-11-2016 AUP74_RS11210 ab1abb750dade373dfe4b81d0ebbd391 429 Pfam PF06689 ClpX C4-type zinc finger 14 51 7.7E-20 T 11-11-2016 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 AUP74_RS11210 ab1abb750dade373dfe4b81d0ebbd391 429 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 417 53.134 T 11-11-2016 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 AUP74_RS11210 ab1abb750dade373dfe4b81d0ebbd391 429 SMART SM00994 13 52 7.6E-24 T 11-11-2016 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 AUP74_RS11210 ab1abb750dade373dfe4b81d0ebbd391 429 SUPERFAMILY SSF52540 62 404 8.14E-72 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11210 ab1abb750dade373dfe4b81d0ebbd391 429 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 319 396 7.3E-16 T 11-11-2016 IPR019489 Clp ATPase, C-terminal AUP74_RS04080 2dbc8a038fa99b64cb0713116b5311cf 414 Pfam PF04116 Fatty acid hydroxylase superfamily 87 219 1.1E-28 T 11-11-2016 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0006633|GO:0016491|GO:0055114 AUP74_RS15820 0bcea5684c56ebab6c845d4e5c2860b9 839 SUPERFAMILY SSF53850 131 314 2.08E-24 T 11-11-2016 AUP74_RS15820 0bcea5684c56ebab6c845d4e5c2860b9 839 SUPERFAMILY SSF53850 327 560 3.77E-37 T 11-11-2016 AUP74_RS15820 0bcea5684c56ebab6c845d4e5c2860b9 839 Gene3D G3DSA:3.40.190.10 291 314 1.1E-10 T 11-11-2016 AUP74_RS15820 0bcea5684c56ebab6c845d4e5c2860b9 839 Gene3D G3DSA:3.40.190.10 131 182 1.1E-10 T 11-11-2016 AUP74_RS15820 0bcea5684c56ebab6c845d4e5c2860b9 839 Gene3D G3DSA:3.40.190.10 333 411 2.3E-20 T 11-11-2016 AUP74_RS15820 0bcea5684c56ebab6c845d4e5c2860b9 839 Gene3D G3DSA:3.40.190.10 522 560 2.3E-20 T 11-11-2016 AUP74_RS15820 0bcea5684c56ebab6c845d4e5c2860b9 839 Gene3D G3DSA:1.10.530.10 578 751 3.0E-40 T 11-11-2016 AUP74_RS15820 0bcea5684c56ebab6c845d4e5c2860b9 839 SMART SM00062 122 326 4.4E-6 T 11-11-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AUP74_RS15820 0bcea5684c56ebab6c845d4e5c2860b9 839 SMART SM00062 335 560 8.3E-27 T 11-11-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AUP74_RS15820 0bcea5684c56ebab6c845d4e5c2860b9 839 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 131 314 1.2E-22 T 11-11-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AUP74_RS15820 0bcea5684c56ebab6c845d4e5c2860b9 839 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 340 558 1.6E-34 T 11-11-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AUP74_RS15820 0bcea5684c56ebab6c845d4e5c2860b9 839 Gene3D G3DSA:3.40.190.10 183 286 1.2E-8 T 11-11-2016 AUP74_RS15820 0bcea5684c56ebab6c845d4e5c2860b9 839 Gene3D G3DSA:3.40.190.10 412 510 9.6E-13 T 11-11-2016 AUP74_RS15820 0bcea5684c56ebab6c845d4e5c2860b9 839 Pfam PF01464 Transglycosylase SLT domain 584 692 1.1E-21 T 11-11-2016 IPR008258 Transglycosylase SLT domain 1 AUP74_RS15820 0bcea5684c56ebab6c845d4e5c2860b9 839 SUPERFAMILY SSF53955 579 749 2.25E-36 T 11-11-2016 IPR023346 Lysozyme-like domain AUP74_RS01280 0bfcaf646117677c26662bd0e6f5bc4d 525 Pfam PF00924 Mechanosensitive ion channel 274 474 8.3E-39 T 11-11-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 AUP74_RS01280 0bfcaf646117677c26662bd0e6f5bc4d 525 SUPERFAMILY SSF82861 233 315 1.96E-13 T 11-11-2016 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 AUP74_RS01280 0bfcaf646117677c26662bd0e6f5bc4d 525 Gene3D G3DSA:3.30.70.100 387 472 6.8E-11 T 11-11-2016 AUP74_RS01280 0bfcaf646117677c26662bd0e6f5bc4d 525 SUPERFAMILY SSF50182 317 375 3.27E-10 T 11-11-2016 IPR010920 LSM domain AUP74_RS01280 0bfcaf646117677c26662bd0e6f5bc4d 525 Gene3D G3DSA:2.30.30.60 334 374 6.0E-10 T 11-11-2016 AUP74_RS01280 0bfcaf646117677c26662bd0e6f5bc4d 525 SUPERFAMILY SSF82689 382 485 4.32E-20 T 11-11-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 AUP74_RS04355 7f24b5a36d068897e1aff7f0e8643105 453 SUPERFAMILY SSF53448 1 249 1.48E-58 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases AUP74_RS04355 7f24b5a36d068897e1aff7f0e8643105 453 Gene3D G3DSA:3.90.550.10 2 240 1.8E-67 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases AUP74_RS04355 7f24b5a36d068897e1aff7f0e8643105 453 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 400 428 - T 11-11-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 AUP74_RS04355 7f24b5a36d068897e1aff7f0e8643105 453 Gene3D G3DSA:2.160.10.10 244 320 3.3E-17 T 11-11-2016 AUP74_RS04355 7f24b5a36d068897e1aff7f0e8643105 453 SUPERFAMILY SSF51161 251 435 1.48E-49 T 11-11-2016 IPR011004 Trimeric LpxA-like AUP74_RS04355 7f24b5a36d068897e1aff7f0e8643105 453 Gene3D G3DSA:2.160.10.10 321 452 2.7E-32 T 11-11-2016 AUP74_RS04355 7f24b5a36d068897e1aff7f0e8643105 453 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 2 449 41.806 T 11-11-2016 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 AUP74_RS04355 7f24b5a36d068897e1aff7f0e8643105 453 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 267 296 1.0E-4 T 11-11-2016 IPR001451 Hexapeptide repeat AUP74_RS04355 7f24b5a36d068897e1aff7f0e8643105 453 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 315 346 3.9E-6 T 11-11-2016 IPR001451 Hexapeptide repeat AUP74_RS04355 7f24b5a36d068897e1aff7f0e8643105 453 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 392 426 2.2E-7 T 11-11-2016 IPR001451 Hexapeptide repeat AUP74_RS04355 7f24b5a36d068897e1aff7f0e8643105 453 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 4 452 1.3E-186 T 11-11-2016 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 AUP74_RS04355 7f24b5a36d068897e1aff7f0e8643105 453 Pfam PF12804 MobA-like NTP transferase domain 5 123 7.2E-25 T 11-11-2016 IPR025877 MobA-like NTP transferase AUP74_RS06840 7115e7598e2929bc7bc25d45782f044a 274 Gene3D G3DSA:2.40.50.140 1 113 5.1E-49 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS06840 7115e7598e2929bc7bc25d45782f044a 274 Gene3D G3DSA:2.30.30.30 119 195 5.9E-32 T 11-11-2016 IPR014722 Ribosomal protein L2 domain 2 AUP74_RS06840 7115e7598e2929bc7bc25d45782f044a 274 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 47.01 T 11-11-2016 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06840 7115e7598e2929bc7bc25d45782f044a 274 PIRSF PIRSF002158 13 274 2.6E-102 T 11-11-2016 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS06840 7115e7598e2929bc7bc25d45782f044a 274 SMART SM01382 124 252 1.7E-92 T 11-11-2016 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 AUP74_RS06840 7115e7598e2929bc7bc25d45782f044a 274 SUPERFAMILY SSF50249 3 124 1.1E-47 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS06840 7115e7598e2929bc7bc25d45782f044a 274 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 250 4.8E-57 T 11-11-2016 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 AUP74_RS06840 7115e7598e2929bc7bc25d45782f044a 274 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 273 1.4E-129 T 11-11-2016 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06840 7115e7598e2929bc7bc25d45782f044a 274 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 11-11-2016 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06840 7115e7598e2929bc7bc25d45782f044a 274 SUPERFAMILY SSF50104 126 272 1.14E-61 T 11-11-2016 IPR008991 Translation protein SH3-like domain AUP74_RS06840 7115e7598e2929bc7bc25d45782f044a 274 Gene3D G3DSA:4.10.950.10 196 272 3.2E-35 T 11-11-2016 IPR014726 Ribosomal protein L2, domain 3 AUP74_RS06840 7115e7598e2929bc7bc25d45782f044a 274 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 1.5E-33 T 11-11-2016 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS06840 7115e7598e2929bc7bc25d45782f044a 274 SMART SM01383 42 118 3.7E-45 T 11-11-2016 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS09260 aca09533e1ed9b468dd07da17f439ac4 171 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 51 62 - T 11-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AUP74_RS09260 aca09533e1ed9b468dd07da17f439ac4 171 Gene3D G3DSA:3.30.70.20 18 108 2.2E-17 T 11-11-2016 AUP74_RS09260 aca09533e1ed9b468dd07da17f439ac4 171 SUPERFAMILY SSF54862 24 135 2.18E-25 T 11-11-2016 AUP74_RS09260 aca09533e1ed9b468dd07da17f439ac4 171 Pfam PF12838 4Fe-4S dicluster domain 50 103 8.6E-11 T 11-11-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AUP74_RS09260 aca09533e1ed9b468dd07da17f439ac4 171 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 90 101 - T 11-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AUP74_RS09260 aca09533e1ed9b468dd07da17f439ac4 171 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 1 139 26.841 T 11-11-2016 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09260 aca09533e1ed9b468dd07da17f439ac4 171 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 7 128 4.6E-49 T 11-11-2016 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS07965 04a456f9b90f7877a234923303fd8139 270 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 149 166 - T 11-11-2016 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AUP74_RS07965 04a456f9b90f7877a234923303fd8139 270 SUPERFAMILY SSF51735 3 125 7.33E-45 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS07965 04a456f9b90f7877a234923303fd8139 270 SUPERFAMILY SSF51735 235 270 7.33E-45 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS07965 04a456f9b90f7877a234923303fd8139 270 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 127 268 7.5E-41 T 11-11-2016 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AUP74_RS07965 04a456f9b90f7877a234923303fd8139 270 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 3 269 2.2E-92 T 11-11-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AUP74_RS07965 04a456f9b90f7877a234923303fd8139 270 PIRSF PIRSF000161 1 270 1.3E-83 T 11-11-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AUP74_RS07965 04a456f9b90f7877a234923303fd8139 270 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 3 124 1.3E-35 T 11-11-2016 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AUP74_RS07965 04a456f9b90f7877a234923303fd8139 270 Gene3D G3DSA:3.40.50.720 2 162 6.4E-55 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS07965 04a456f9b90f7877a234923303fd8139 270 SUPERFAMILY SSF55347 127 235 9.16E-38 T 11-11-2016 AUP74_RS07965 04a456f9b90f7877a234923303fd8139 270 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 3 269 35.041 T 11-11-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AUP74_RS12715 a204dceeaed82ff91a4f114d6ca8db49 232 ProSitePatterns PS00449 ATP synthase a subunit signature. 159 168 - T 11-11-2016 IPR023011 ATPase, F0 complex, subunit A, active site Reactome: R-HSA-163210 AUP74_RS12715 a204dceeaed82ff91a4f114d6ca8db49 232 PRINTS PR00123 ATP synthase A subunit signature 140 155 1.4E-15 T 11-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 AUP74_RS12715 a204dceeaed82ff91a4f114d6ca8db49 232 PRINTS PR00123 ATP synthase A subunit signature 156 178 1.4E-15 T 11-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 AUP74_RS12715 a204dceeaed82ff91a4f114d6ca8db49 232 PRINTS PR00123 ATP synthase A subunit signature 200 215 1.4E-15 T 11-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 AUP74_RS12715 a204dceeaed82ff91a4f114d6ca8db49 232 PRINTS PR00123 ATP synthase A subunit signature 80 96 1.4E-15 T 11-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 AUP74_RS12715 a204dceeaed82ff91a4f114d6ca8db49 232 SUPERFAMILY SSF81336 73 213 7.45E-33 T 11-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 AUP74_RS12715 a204dceeaed82ff91a4f114d6ca8db49 232 Gene3D G3DSA:1.20.120.220 73 215 3.6E-36 T 11-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 AUP74_RS12715 a204dceeaed82ff91a4f114d6ca8db49 232 Hamap MF_01393 ATP synthase subunit a [atpB]. 1 220 14.265 T 11-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 AUP74_RS12715 a204dceeaed82ff91a4f114d6ca8db49 232 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 20 214 2.4E-30 T 11-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 AUP74_RS12715 a204dceeaed82ff91a4f114d6ca8db49 232 Pfam PF00119 ATP synthase A chain 23 213 3.0E-43 T 11-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 AUP74_RS03590 2644ba2971b3d76b60469fc6f0b00a30 244 Pfam PF06629 MltA-interacting protein MipA 14 238 3.6E-23 T 11-11-2016 IPR010583 MltA-interacting MipA AUP74_RS03590 2644ba2971b3d76b60469fc6f0b00a30 244 Gene3D G3DSA:2.40.170.20 127 241 1.1E-4 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS06370 f826ff53fb80ccbe622029b856e6d54c 406 SUPERFAMILY SSF81301 1 119 3.16E-29 T 11-11-2016 AUP74_RS06370 f826ff53fb80ccbe622029b856e6d54c 406 Hamap MF_01261 Multifunctional CCA protein [cca]. 1 404 52.016 T 11-11-2016 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 AUP74_RS06370 f826ff53fb80ccbe622029b856e6d54c 406 Gene3D G3DSA:3.30.460.10 1 121 1.0E-29 T 11-11-2016 AUP74_RS06370 f826ff53fb80ccbe622029b856e6d54c 406 SUPERFAMILY SSF81891 120 358 4.45E-53 T 11-11-2016 AUP74_RS06370 f826ff53fb80ccbe622029b856e6d54c 406 Hamap MF_01262 CCA-adding enzyme [cca]. 1 398 41.373 T 11-11-2016 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 AUP74_RS06370 f826ff53fb80ccbe622029b856e6d54c 406 PIRSF PIRSF000813 1 405 3.3E-186 T 11-11-2016 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 AUP74_RS06370 f826ff53fb80ccbe622029b856e6d54c 406 Gene3D G3DSA:1.10.3090.10 122 357 2.2E-53 T 11-11-2016 AUP74_RS06370 f826ff53fb80ccbe622029b856e6d54c 406 Pfam PF01743 Poly A polymerase head domain 3 122 4.1E-18 T 11-11-2016 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 AUP74_RS06370 f826ff53fb80ccbe622029b856e6d54c 406 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 149 212 1.0E-12 T 11-11-2016 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 AUP74_RS06370 f826ff53fb80ccbe622029b856e6d54c 406 Pfam PF01966 HD domain 241 307 7.1E-6 T 11-11-2016 IPR006674 HD domain AUP74_RS00810 cafe3846876deb2c5bf82c60d929b316 445 Pfam PF13188 PAS domain 121 179 2.4E-5 T 11-11-2016 IPR000014 PAS domain AUP74_RS00810 cafe3846876deb2c5bf82c60d929b316 445 SUPERFAMILY SSF55874 307 442 1.03E-29 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS00810 cafe3846876deb2c5bf82c60d929b316 445 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 339 443 3.1E-18 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS00810 cafe3846876deb2c5bf82c60d929b316 445 SUPERFAMILY SSF55785 108 218 1.99E-5 T 11-11-2016 IPR000014 PAS domain AUP74_RS00810 cafe3846876deb2c5bf82c60d929b316 445 Gene3D G3DSA:3.30.565.10 280 442 3.3E-29 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS00810 cafe3846876deb2c5bf82c60d929b316 445 Gene3D G3DSA:3.30.450.20 116 218 1.2E-7 T 11-11-2016 AUP74_RS00810 cafe3846876deb2c5bf82c60d929b316 445 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 389 4.4E-9 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS00810 cafe3846876deb2c5bf82c60d929b316 445 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 441 4.4E-9 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS00810 cafe3846876deb2c5bf82c60d929b316 445 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 422 4.4E-9 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS00810 cafe3846876deb2c5bf82c60d929b316 445 SMART SM00387 338 444 3.2E-29 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS11865 53958921202972d4222e752c9427dfa9 212 Gene3D G3DSA:3.40.50.450 30 210 3.9E-61 T 11-11-2016 AUP74_RS11865 53958921202972d4222e752c9427dfa9 212 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 32 204 8.6E-44 T 11-11-2016 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG AUP74_RS11865 53958921202972d4222e752c9427dfa9 212 SUPERFAMILY SSF102405 3 204 7.17E-60 T 11-11-2016 AUP74_RS11865 53958921202972d4222e752c9427dfa9 212 Pfam PF03641 Possible lysine decarboxylase 74 203 1.1E-31 T 11-11-2016 IPR031100 LOG family AUP74_RS03115 dfbad8d66e9f7888f5df57731785c1f4 126 SUPERFAMILY SSF54637 8 123 9.92E-17 T 11-11-2016 IPR029069 HotDog domain AUP74_RS03115 dfbad8d66e9f7888f5df57731785c1f4 126 Gene3D G3DSA:3.10.129.10 8 124 1.3E-17 T 11-11-2016 IPR029069 HotDog domain AUP74_RS03240 ba97bd13c464ccea2fd88704488360a5 195 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 61 74 - T 11-11-2016 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 AUP74_RS03240 ba97bd13c464ccea2fd88704488360a5 195 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 2 195 42.423 T 11-11-2016 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 AUP74_RS03240 ba97bd13c464ccea2fd88704488360a5 195 Gene3D G3DSA:3.30.230.40 1 88 2.2E-37 T 11-11-2016 AUP74_RS03240 ba97bd13c464ccea2fd88704488360a5 195 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 156 168 - T 11-11-2016 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 AUP74_RS03240 ba97bd13c464ccea2fd88704488360a5 195 SUPERFAMILY SSF54211 1 86 7.84E-33 T 11-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold AUP74_RS03240 ba97bd13c464ccea2fd88704488360a5 195 Gene3D G3DSA:3.30.230.40 90 195 1.5E-33 T 11-11-2016 AUP74_RS03240 ba97bd13c464ccea2fd88704488360a5 195 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 31 174 5.6E-64 T 11-11-2016 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 AUP74_RS03240 ba97bd13c464ccea2fd88704488360a5 195 SUPERFAMILY SSF54211 88 178 7.21E-36 T 11-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold AUP74_RS06505 1149e029bf6cbd8985fd2b70c9f18180 387 TIGRFAM TIGR02098 MJ0042_CXXC: MJ0042 family finger-like domain 5 40 2.6E-15 T 11-11-2016 IPR011723 Zinc finger/thioredoxin putative AUP74_RS06505 1149e029bf6cbd8985fd2b70c9f18180 387 Pfam PF11906 Protein of unknown function (DUF3426) 237 382 1.1E-36 T 11-11-2016 IPR021834 Protein of unknown function DUF3426 AUP74_RS06505 1149e029bf6cbd8985fd2b70c9f18180 387 Pfam PF13717 zinc-ribbon domain 6 39 8.6E-10 T 11-11-2016 AUP74_RS08455 a9d19e5d79ed2e01b8adb997d7436b88 383 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 273 363 2.7E-25 T 11-11-2016 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AUP74_RS08455 a9d19e5d79ed2e01b8adb997d7436b88 383 Gene3D G3DSA:3.40.710.10 6 271 3.5E-99 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS08455 a9d19e5d79ed2e01b8adb997d7436b88 383 Gene3D G3DSA:2.60.410.10 273 363 1.2E-27 T 11-11-2016 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AUP74_RS08455 a9d19e5d79ed2e01b8adb997d7436b88 383 SMART SM00936 273 363 7.4E-32 T 11-11-2016 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AUP74_RS08455 a9d19e5d79ed2e01b8adb997d7436b88 383 SUPERFAMILY SSF69189 273 365 1.06E-24 T 11-11-2016 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AUP74_RS08455 a9d19e5d79ed2e01b8adb997d7436b88 383 SUPERFAMILY SSF56601 1 272 5.24E-84 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS08455 a9d19e5d79ed2e01b8adb997d7436b88 383 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 28 253 1.3E-84 T 11-11-2016 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 AUP74_RS08455 a9d19e5d79ed2e01b8adb997d7436b88 383 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 140 153 4.0E-18 T 11-11-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 AUP74_RS08455 a9d19e5d79ed2e01b8adb997d7436b88 383 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 60 71 4.0E-18 T 11-11-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 AUP74_RS08455 a9d19e5d79ed2e01b8adb997d7436b88 383 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 113 130 4.0E-18 T 11-11-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 AUP74_RS01880 1aec65aed1b0c8647bfab03edead9b96 234 Gene3D G3DSA:3.30.1600.10 112 156 5.5E-25 T 11-11-2016 IPR026591 Sirtuin family, catalytic core small domain AUP74_RS01880 1aec65aed1b0c8647bfab03edead9b96 234 Gene3D G3DSA:3.30.1600.10 20 59 5.5E-25 T 11-11-2016 IPR026591 Sirtuin family, catalytic core small domain AUP74_RS01880 1aec65aed1b0c8647bfab03edead9b96 234 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 4 234 58.297 T 11-11-2016 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 AUP74_RS01880 1aec65aed1b0c8647bfab03edead9b96 234 Gene3D G3DSA:3.40.50.1220 163 227 7.8E-41 T 11-11-2016 IPR029035 DHS-like NAD/FAD-binding domain AUP74_RS01880 1aec65aed1b0c8647bfab03edead9b96 234 Gene3D G3DSA:3.40.50.1220 69 111 7.8E-41 T 11-11-2016 IPR029035 DHS-like NAD/FAD-binding domain AUP74_RS01880 1aec65aed1b0c8647bfab03edead9b96 234 Gene3D G3DSA:3.40.50.1220 3 19 7.8E-41 T 11-11-2016 IPR029035 DHS-like NAD/FAD-binding domain AUP74_RS01880 1aec65aed1b0c8647bfab03edead9b96 234 Pfam PF02146 Sir2 family 11 184 3.8E-49 T 11-11-2016 IPR003000 Sirtuin family GO:0070403 AUP74_RS01880 1aec65aed1b0c8647bfab03edead9b96 234 SUPERFAMILY SSF52467 2 232 1.22E-73 T 11-11-2016 IPR029035 DHS-like NAD/FAD-binding domain AUP74_RS13205 b2706dd9452b5045f388075c3fc6d145 284 Hamap MF_00258 Glutamate racemase [murI]. 16 270 29.354 T 11-11-2016 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AUP74_RS13205 b2706dd9452b5045f388075c3fc6d145 284 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 83 91 - T 11-11-2016 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AUP74_RS13205 b2706dd9452b5045f388075c3fc6d145 284 SUPERFAMILY SSF53681 121 262 3.05E-29 T 11-11-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AUP74_RS13205 b2706dd9452b5045f388075c3fc6d145 284 Pfam PF01177 Asp/Glu/Hydantoin racemase 63 230 5.5E-22 T 11-11-2016 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AUP74_RS13205 b2706dd9452b5045f388075c3fc6d145 284 Gene3D G3DSA:3.40.50.1860 19 182 5.3E-40 T 11-11-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AUP74_RS13205 b2706dd9452b5045f388075c3fc6d145 284 SUPERFAMILY SSF53681 19 119 3.24E-25 T 11-11-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AUP74_RS13205 b2706dd9452b5045f388075c3fc6d145 284 TIGRFAM TIGR00067 glut_race: glutamate racemase 19 239 1.8E-51 T 11-11-2016 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AUP74_RS02810 b16831c5bd3f54635097fe51fd911e9d 276 Gene3D G3DSA:3.30.470.20 68 149 4.0E-4 T 11-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 AUP74_RS02810 b16831c5bd3f54635097fe51fd911e9d 276 Gene3D G3DSA:3.30.470.20 150 227 5.6E-11 T 11-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 AUP74_RS02810 b16831c5bd3f54635097fe51fd911e9d 276 SUPERFAMILY SSF56059 60 251 1.48E-27 T 11-11-2016 AUP74_RS02810 b16831c5bd3f54635097fe51fd911e9d 276 Pfam PF08443 RimK-like ATP-grasp domain 83 237 1.5E-18 T 11-11-2016 IPR013651 ATP-grasp fold, RimK-type AUP74_RS05845 6be544e4a8353bef011a2ff8bdfad16e 291 PIRSF PIRSF005651 1 291 3.1E-92 T 11-11-2016 IPR010200 HflC GO:0016021|GO:0052547 AUP74_RS05845 6be544e4a8353bef011a2ff8bdfad16e 291 SUPERFAMILY SSF117892 53 190 1.57E-25 T 11-11-2016 IPR001107 Band 7 domain AUP74_RS05845 6be544e4a8353bef011a2ff8bdfad16e 291 Pfam PF01145 SPFH domain / Band 7 family 25 202 1.2E-29 T 11-11-2016 IPR001107 Band 7 domain AUP74_RS05845 6be544e4a8353bef011a2ff8bdfad16e 291 SMART SM00244 21 185 7.6E-37 T 11-11-2016 IPR001107 Band 7 domain AUP74_RS05845 6be544e4a8353bef011a2ff8bdfad16e 291 TIGRFAM TIGR01932 hflC: HflC protein 152 285 1.9E-47 T 11-11-2016 IPR010200 HflC GO:0016021|GO:0052547 AUP74_RS05845 6be544e4a8353bef011a2ff8bdfad16e 291 PRINTS PR00721 Stomatin signature 180 201 2.5E-6 T 11-11-2016 IPR001972 Stomatin family GO:0016020 AUP74_RS05845 6be544e4a8353bef011a2ff8bdfad16e 291 PRINTS PR00721 Stomatin signature 28 50 2.5E-6 T 11-11-2016 IPR001972 Stomatin family GO:0016020 AUP74_RS05845 6be544e4a8353bef011a2ff8bdfad16e 291 PRINTS PR00721 Stomatin signature 161 179 2.5E-6 T 11-11-2016 IPR001972 Stomatin family GO:0016020 AUP74_RS05845 6be544e4a8353bef011a2ff8bdfad16e 291 PRINTS PR00721 Stomatin signature 115 132 2.5E-6 T 11-11-2016 IPR001972 Stomatin family GO:0016020 AUP74_RS08335 070d945ceee2ccd53bdd242f2b50f9da 457 SUPERFAMILY SSF55931 117 455 4.22E-103 T 11-11-2016 AUP74_RS08335 070d945ceee2ccd53bdd242f2b50f9da 457 Pfam PF00120 Glutamine synthetase, catalytic domain 117 453 3.7E-94 T 11-11-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AUP74_RS08335 070d945ceee2ccd53bdd242f2b50f9da 457 Gene3D G3DSA:3.30.590.10 119 445 1.9E-93 T 11-11-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 AUP74_RS08335 070d945ceee2ccd53bdd242f2b50f9da 457 SMART SM01230 116 372 5.9E-97 T 11-11-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AUP74_RS12830 1fb20af071d01b487a1d9dc3ec47d58f 125 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 14 115 29.391 T 11-11-2016 IPR022935 ATP-dependent Clp protease adaptor protein ClpS AUP74_RS12830 1fb20af071d01b487a1d9dc3ec47d58f 125 SUPERFAMILY SSF54736 35 118 8.89E-33 T 11-11-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like AUP74_RS12830 1fb20af071d01b487a1d9dc3ec47d58f 125 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 37 116 8.4E-36 T 11-11-2016 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 AUP74_RS12830 1fb20af071d01b487a1d9dc3ec47d58f 125 Gene3D G3DSA:3.30.1390.10 28 120 1.7E-44 T 11-11-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like AUP74_RS07025 5d64cf181e5a32ba29b3c7604e618af9 320 Gene3D G3DSA:1.10.600.10 4 319 4.9E-102 T 11-11-2016 IPR008949 Isoprenoid synthase domain AUP74_RS07025 5d64cf181e5a32ba29b3c7604e618af9 320 SUPERFAMILY SSF48576 5 319 1.35E-100 T 11-11-2016 IPR008949 Isoprenoid synthase domain AUP74_RS07025 5d64cf181e5a32ba29b3c7604e618af9 320 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 79 93 - T 11-11-2016 IPR000092 Polyprenyl synthetase GO:0008299 AUP74_RS07025 5d64cf181e5a32ba29b3c7604e618af9 320 Pfam PF00348 Polyprenyl synthetase 29 264 2.0E-75 T 11-11-2016 IPR000092 Polyprenyl synthetase GO:0008299 AUP74_RS06115 b82b343e374dfaf766f96920c595d001 265 SUPERFAMILY SSF52096 2 260 2.99E-75 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS06115 b82b343e374dfaf766f96920c595d001 265 Gene3D G3DSA:3.90.226.10 2 202 9.6E-62 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS06115 b82b343e374dfaf766f96920c595d001 265 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 103 123 - T 11-11-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 AUP74_RS06115 b82b343e374dfaf766f96920c595d001 265 Gene3D G3DSA:1.10.12.10 205 261 2.1E-11 T 11-11-2016 IPR014748 Crontonase, C-terminal AUP74_RS06115 b82b343e374dfaf766f96920c595d001 265 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 260 4.9E-55 T 11-11-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 AUP74_RS10735 96155ad7a435c45ddbc99b0c1d25dac4 319 SUPERFAMILY SSF56235 5 277 3.94E-73 T 11-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal AUP74_RS10735 96155ad7a435c45ddbc99b0c1d25dac4 319 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 5 273 2.3E-41 T 11-11-2016 IPR029132 Choloylglycine hydrolase/NAAA C-terminal AUP74_RS10735 96155ad7a435c45ddbc99b0c1d25dac4 319 Gene3D G3DSA:3.60.60.10 5 288 2.5E-81 T 11-11-2016 IPR003199 Choloylglycine hydrolase/Peptidase C59 family GO:0016811 Reactome: R-HSA-1660662 AUP74_RS04655 45e4be3d96891ca4af98d107f52f0f4c 185 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 100 133 1.1E-5 T 11-11-2016 IPR001451 Hexapeptide repeat AUP74_RS04655 45e4be3d96891ca4af98d107f52f0f4c 185 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 17 50 2.9E-6 T 11-11-2016 IPR001451 Hexapeptide repeat AUP74_RS04655 45e4be3d96891ca4af98d107f52f0f4c 185 Gene3D G3DSA:2.160.10.10 15 179 6.1E-44 T 11-11-2016 AUP74_RS04655 45e4be3d96891ca4af98d107f52f0f4c 185 SUPERFAMILY SSF51161 16 180 8.32E-43 T 11-11-2016 IPR011004 Trimeric LpxA-like AUP74_RS09415 c583710e80ef1ed0b7a16bccd4cc5465 622 Gene3D G3DSA:1.20.1640.10 456 616 1.1E-25 T 11-11-2016 AUP74_RS09415 c583710e80ef1ed0b7a16bccd4cc5465 622 Pfam PF02355 Protein export membrane protein 445 606 5.7E-20 T 11-11-2016 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial AUP74_RS09415 c583710e80ef1ed0b7a16bccd4cc5465 622 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 124 608 4.8E-133 T 11-11-2016 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 AUP74_RS09415 c583710e80ef1ed0b7a16bccd4cc5465 622 Pfam PF13721 SecD export protein N-terminal TM region 1 104 1.5E-31 T 11-11-2016 IPR027398 SecD export protein N-terminal TM domain AUP74_RS09415 c583710e80ef1ed0b7a16bccd4cc5465 622 PRINTS PR00702 Acriflavin resistance protein family signature 457 480 1.4E-5 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS09415 c583710e80ef1ed0b7a16bccd4cc5465 622 PRINTS PR00702 Acriflavin resistance protein family signature 510 534 1.4E-5 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS09415 c583710e80ef1ed0b7a16bccd4cc5465 622 PRINTS PR00702 Acriflavin resistance protein family signature 585 608 1.4E-5 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS09415 c583710e80ef1ed0b7a16bccd4cc5465 622 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 382 601 4.6E-73 T 11-11-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial AUP74_RS09415 c583710e80ef1ed0b7a16bccd4cc5465 622 Pfam PF07549 SecD/SecF GG Motif 118 141 6.1E-6 T 11-11-2016 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site AUP74_RS09415 c583710e80ef1ed0b7a16bccd4cc5465 622 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 2 622 47.765 T 11-11-2016 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 AUP74_RS09415 c583710e80ef1ed0b7a16bccd4cc5465 622 SUPERFAMILY SSF82866 331 351 1.28E-45 T 11-11-2016 AUP74_RS09415 c583710e80ef1ed0b7a16bccd4cc5465 622 SUPERFAMILY SSF82866 418 613 1.28E-45 T 11-11-2016 AUP74_RS02665 0678a1c2c6cd4bbea3c9ffbd4c96d374 891 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 45 881 3.3E-244 T 11-11-2016 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 AUP74_RS02665 0678a1c2c6cd4bbea3c9ffbd4c96d374 891 SUPERFAMILY SSF63737 55 237 2.75E-38 T 11-11-2016 AUP74_RS02665 0678a1c2c6cd4bbea3c9ffbd4c96d374 891 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 299 309 6.1E-20 T 11-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AUP74_RS02665 0678a1c2c6cd4bbea3c9ffbd4c96d374 891 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 220 235 6.1E-20 T 11-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AUP74_RS02665 0678a1c2c6cd4bbea3c9ffbd4c96d374 891 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 333 348 6.1E-20 T 11-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AUP74_RS02665 0678a1c2c6cd4bbea3c9ffbd4c96d374 891 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 173 188 6.1E-20 T 11-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AUP74_RS02665 0678a1c2c6cd4bbea3c9ffbd4c96d374 891 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 352 364 6.1E-20 T 11-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AUP74_RS02665 0678a1c2c6cd4bbea3c9ffbd4c96d374 891 Gene3D G3DSA:1.10.390.10 346 492 2.6E-41 T 11-11-2016 AUP74_RS02665 0678a1c2c6cd4bbea3c9ffbd4c96d374 891 Pfam PF11838 ERAP1-like C-terminal domain 564 874 2.0E-23 T 11-11-2016 IPR024571 ERAP1-like C-terminal domain AUP74_RS02665 0678a1c2c6cd4bbea3c9ffbd4c96d374 891 Pfam PF01433 Peptidase family M1 55 425 2.2E-79 T 11-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AUP74_RS02665 0678a1c2c6cd4bbea3c9ffbd4c96d374 891 SUPERFAMILY SSF55486 245 490 5.77E-73 T 11-11-2016 AUP74_RS14915 5e3e0240db6f3a1e9ca4ec3f68bd4b4b 205 Pfam PF13578 Methyltransferase domain 38 166 8.3E-20 T 11-11-2016 AUP74_RS14915 5e3e0240db6f3a1e9ca4ec3f68bd4b4b 205 SUPERFAMILY SSF53335 24 173 1.16E-8 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS14915 5e3e0240db6f3a1e9ca4ec3f68bd4b4b 205 Gene3D G3DSA:3.40.50.150 21 167 1.8E-8 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS15350 7f327255ac9f904093a81cf3b74f8f01 131 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 126 5.0E-15 T 11-11-2016 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 AUP74_RS15350 7f327255ac9f904093a81cf3b74f8f01 131 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 2 126 6.1E-27 T 11-11-2016 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 AUP74_RS15350 7f327255ac9f904093a81cf3b74f8f01 131 Gene3D G3DSA:3.90.470.20 2 126 2.2E-33 T 11-11-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 AUP74_RS15350 7f327255ac9f904093a81cf3b74f8f01 131 SUPERFAMILY SSF56214 2 126 4.19E-27 T 11-11-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 AUP74_RS15350 7f327255ac9f904093a81cf3b74f8f01 131 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 127 22.7 T 11-11-2016 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 AUP74_RS15350 7f327255ac9f904093a81cf3b74f8f01 131 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 123 2.7E-20 T 11-11-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 AUP74_RS15350 7f327255ac9f904093a81cf3b74f8f01 131 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 2 126 3.9E-31 T 11-11-2016 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 AUP74_RS06500 de05134142a04f637c45a4d163aed9f2 312 Gene3D G3DSA:1.10.1200.80 235 303 3.2E-18 T 11-11-2016 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 AUP74_RS06500 de05134142a04f637c45a4d163aed9f2 312 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 1 300 3.7E-116 T 11-11-2016 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 AUP74_RS06500 de05134142a04f637c45a4d163aed9f2 312 SUPERFAMILY SSF51395 1 302 5.31E-85 T 11-11-2016 AUP74_RS06500 de05134142a04f637c45a4d163aed9f2 312 Hamap MF_02042 tRNA-dihydrouridine synthase B [dusB]. 1 305 44.998 T 11-11-2016 IPR032887 tRNA-dihydrouridine synthase B GO:0002943|GO:0017150 AUP74_RS06500 de05134142a04f637c45a4d163aed9f2 312 PIRSF PIRSF006621 1 308 6.8E-98 T 11-11-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 AUP74_RS06500 de05134142a04f637c45a4d163aed9f2 312 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 78 96 - T 11-11-2016 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 AUP74_RS06500 de05134142a04f637c45a4d163aed9f2 312 Pfam PF01207 Dihydrouridine synthase (Dus) 1 297 1.4E-99 T 11-11-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 AUP74_RS06500 de05134142a04f637c45a4d163aed9f2 312 Gene3D G3DSA:3.20.20.70 1 230 1.1E-79 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS00850 e7861277a4e788c2396b49fe9f1fe9bd 481 Pfam PF06863 Protein of unknown function (DUF1254) 78 210 1.3E-42 T 11-11-2016 IPR010679 Domain of unknown function DUF1254 AUP74_RS00850 e7861277a4e788c2396b49fe9f1fe9bd 481 Gene3D G3DSA:1.10.3360.10 227 302 4.1E-9 T 11-11-2016 IPR023289 VPA0735-like domain AUP74_RS00850 e7861277a4e788c2396b49fe9f1fe9bd 481 Pfam PF06742 Protein of unknown function (DUF1214) 347 459 9.0E-38 T 11-11-2016 IPR010621 Domain of unknown function DUF1214 AUP74_RS00850 e7861277a4e788c2396b49fe9f1fe9bd 481 SUPERFAMILY SSF160935 16 478 8.37E-131 T 11-11-2016 AUP74_RS00850 e7861277a4e788c2396b49fe9f1fe9bd 481 Gene3D G3DSA:2.60.120.600 303 479 4.4E-57 T 11-11-2016 IPR010621 Domain of unknown function DUF1214 AUP74_RS00850 e7861277a4e788c2396b49fe9f1fe9bd 481 Gene3D G3DSA:2.60.40.1610 91 226 6.2E-23 T 11-11-2016 IPR010679 Domain of unknown function DUF1254 AUP74_RS06985 c8c614bd03bae2fd176f3b3588ecfccf 941 SUPERFAMILY SSF52540 436 569 2.86E-42 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS06985 c8c614bd03bae2fd176f3b3588ecfccf 941 SUPERFAMILY SSF52540 6 204 2.86E-42 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS06985 c8c614bd03bae2fd176f3b3588ecfccf 941 SUPERFAMILY SSF52540 617 912 4.6E-53 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS06985 c8c614bd03bae2fd176f3b3588ecfccf 941 ProSitePatterns PS00211 ABC transporters family signature. 487 501 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AUP74_RS06985 c8c614bd03bae2fd176f3b3588ecfccf 941 Gene3D G3DSA:3.40.50.300 3 89 6.4E-55 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS06985 c8c614bd03bae2fd176f3b3588ecfccf 941 Gene3D G3DSA:3.40.50.300 607 674 2.6E-59 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS06985 c8c614bd03bae2fd176f3b3588ecfccf 941 Gene3D G3DSA:3.40.50.300 821 938 2.6E-59 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS06985 c8c614bd03bae2fd176f3b3588ecfccf 941 Gene3D G3DSA:3.40.50.300 478 597 6.4E-55 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS06985 c8c614bd03bae2fd176f3b3588ecfccf 941 Hamap MF_00205 UvrABC system protein A [uvrA]. 1 940 22.846 T 11-11-2016 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 AUP74_RS06985 c8c614bd03bae2fd176f3b3588ecfccf 941 Gene3D G3DSA:3.30.1490.20 130 153 5.3E-27 T 11-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 AUP74_RS06985 c8c614bd03bae2fd176f3b3588ecfccf 941 Gene3D G3DSA:3.30.1490.20 200 248 5.3E-27 T 11-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 AUP74_RS06985 c8c614bd03bae2fd176f3b3588ecfccf 941 Gene3D G3DSA:1.20.1580.10 91 129 5.1E-52 T 11-11-2016 AUP74_RS06985 c8c614bd03bae2fd176f3b3588ecfccf 941 Gene3D G3DSA:1.20.1580.10 406 477 5.1E-52 T 11-11-2016 AUP74_RS06985 c8c614bd03bae2fd176f3b3588ecfccf 941 Gene3D G3DSA:1.20.1580.10 250 283 5.1E-52 T 11-11-2016 AUP74_RS06985 c8c614bd03bae2fd176f3b3588ecfccf 941 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 4 925 0.0 T 11-11-2016 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 AUP74_RS06985 c8c614bd03bae2fd176f3b3588ecfccf 941 ProSitePatterns PS00211 ABC transporters family signature. 830 844 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AUP74_RS06985 c8c614bd03bae2fd176f3b3588ecfccf 941 Gene3D G3DSA:1.20.1580.10 694 820 1.4E-56 T 11-11-2016 AUP74_RS06985 c8c614bd03bae2fd176f3b3588ecfccf 941 Gene3D G3DSA:1.10.8.280 285 405 1.5E-44 T 11-11-2016 AUP74_RS03800 3025978b02c8df40c141fd122fe4b4d7 716 SUPERFAMILY SSF56935 30 716 7.33E-109 T 11-11-2016 AUP74_RS03800 3025978b02c8df40c141fd122fe4b4d7 716 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 699 716 - T 11-11-2016 IPR010917 TonB-dependent receptor, conserved site AUP74_RS03800 3025978b02c8df40c141fd122fe4b4d7 716 Gene3D G3DSA:2.170.130.10 29 167 2.9E-31 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS03800 3025978b02c8df40c141fd122fe4b4d7 716 Pfam PF07715 TonB-dependent Receptor Plug Domain 52 157 7.1E-16 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS03800 3025978b02c8df40c141fd122fe4b4d7 716 Gene3D G3DSA:2.40.170.20 168 716 1.3E-72 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS03800 3025978b02c8df40c141fd122fe4b4d7 716 Pfam PF00593 TonB dependent receptor 445 696 9.2E-18 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS07990 64a355b7402648e2c0b6861e81ec4f37 158 SUPERFAMILY SSF54534 82 157 5.49E-25 T 11-11-2016 AUP74_RS07990 64a355b7402648e2c0b6861e81ec4f37 158 Pfam PF03449 Transcription elongation factor, N-terminal 4 74 3.3E-32 T 11-11-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 AUP74_RS07990 64a355b7402648e2c0b6861e81ec4f37 158 Gene3D G3DSA:1.10.287.180 3 75 1.0E-34 T 11-11-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 AUP74_RS07990 64a355b7402648e2c0b6861e81ec4f37 158 PIRSF PIRSF006092 2 158 7.1E-52 T 11-11-2016 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 AUP74_RS07990 64a355b7402648e2c0b6861e81ec4f37 158 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 156 33.397 T 11-11-2016 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 AUP74_RS07990 64a355b7402648e2c0b6861e81ec4f37 158 SUPERFAMILY SSF46557 3 77 4.97E-29 T 11-11-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 AUP74_RS07990 64a355b7402648e2c0b6861e81ec4f37 158 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 5 156 7.5E-60 T 11-11-2016 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 AUP74_RS07990 64a355b7402648e2c0b6861e81ec4f37 158 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 82 156 2.8E-30 T 11-11-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 AUP74_RS07990 64a355b7402648e2c0b6861e81ec4f37 158 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 121 137 - T 11-11-2016 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 AUP74_RS07990 64a355b7402648e2c0b6861e81ec4f37 158 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 11-11-2016 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 AUP74_RS07990 64a355b7402648e2c0b6861e81ec4f37 158 Gene3D G3DSA:3.10.50.30 81 156 1.4E-31 T 11-11-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 AUP74_RS01100 f17ebfc0eb7edc2a9b0676b4f1f429b9 157 Pfam PF01899 Na+/H+ ion antiporter subunit 7 154 1.1E-39 T 11-11-2016 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 AUP74_RS01100 f17ebfc0eb7edc2a9b0676b4f1f429b9 157 PIRSF PIRSF019239 1 157 5.8E-41 T 11-11-2016 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 AUP74_RS08370 0732a578ac22b9210d96992809f6d2a7 204 SUPERFAMILY SSF52507 1 194 1.15E-51 T 11-11-2016 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 AUP74_RS08370 0732a578ac22b9210d96992809f6d2a7 204 Gene3D G3DSA:3.40.50.1950 1 194 3.0E-65 T 11-11-2016 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 AUP74_RS08370 0732a578ac22b9210d96992809f6d2a7 204 Pfam PF02441 Flavoprotein 1 138 1.3E-19 T 11-11-2016 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 AUP74_RS08370 0732a578ac22b9210d96992809f6d2a7 204 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 1 194 31.472 T 11-11-2016 IPR004507 Flavin prenyltransferase UbiX/Pad1 AUP74_RS08370 0732a578ac22b9210d96992809f6d2a7 204 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 1 192 7.9E-57 T 11-11-2016 IPR004507 Flavin prenyltransferase UbiX/Pad1 AUP74_RS15240 071495e91e613672a35b8d80bd459c6a 310 Gene3D G3DSA:2.30.30.60 121 168 2.8E-15 T 11-11-2016 AUP74_RS15240 071495e91e613672a35b8d80bd459c6a 310 Gene3D G3DSA:3.30.70.100 174 260 8.8E-17 T 11-11-2016 AUP74_RS15240 071495e91e613672a35b8d80bd459c6a 310 SUPERFAMILY SSF82861 21 104 7.85E-6 T 11-11-2016 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 AUP74_RS15240 071495e91e613672a35b8d80bd459c6a 310 Pfam PF00924 Mechanosensitive ion channel 64 261 1.2E-37 T 11-11-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 AUP74_RS15240 071495e91e613672a35b8d80bd459c6a 310 SUPERFAMILY SSF50182 105 168 9.81E-16 T 11-11-2016 IPR010920 LSM domain AUP74_RS15240 071495e91e613672a35b8d80bd459c6a 310 SUPERFAMILY SSF82689 173 273 4.32E-21 T 11-11-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 AUP74_RS03485 749f5997c5305ee143fd6c406ae24bfc 281 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 228 242 - T 11-11-2016 IPR020550 Inositol monophosphatase, conserved site GO:0046854 AUP74_RS03485 749f5997c5305ee143fd6c406ae24bfc 281 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 86 99 - T 11-11-2016 IPR020583 Inositol monophosphatase, metal-binding site AUP74_RS03485 749f5997c5305ee143fd6c406ae24bfc 281 TIGRFAM TIGR01331 bisphos_cysQ: 3'(2'),5'-bisphosphate nucleotidase 6 267 1.2E-86 T 11-11-2016 IPR006240 3(2),5 -bisphosphate nucleotidase, bacterial GO:0000287|GO:0016020 KEGG: 00920+3.1.3.7 AUP74_RS03485 749f5997c5305ee143fd6c406ae24bfc 281 Gene3D G3DSA:3.40.190.80 167 271 2.4E-40 T 11-11-2016 AUP74_RS03485 749f5997c5305ee143fd6c406ae24bfc 281 Gene3D G3DSA:3.30.540.10 4 159 4.6E-40 T 11-11-2016 AUP74_RS03485 749f5997c5305ee143fd6c406ae24bfc 281 Pfam PF00459 Inositol monophosphatase family 10 248 9.6E-47 T 11-11-2016 IPR000760 Inositol monophosphatase GO:0046854 AUP74_RS03485 749f5997c5305ee143fd6c406ae24bfc 281 SUPERFAMILY SSF56655 5 279 6.02E-69 T 11-11-2016 AUP74_RS00445 6e941a9756e0e45061855cb3a61f01f6 134 PRINTS PR00502 NUDIX hydrolase family signature 48 63 3.9E-6 T 11-11-2016 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AUP74_RS00445 6e941a9756e0e45061855cb3a61f01f6 134 PRINTS PR00502 NUDIX hydrolase family signature 34 48 3.9E-6 T 11-11-2016 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AUP74_RS00445 6e941a9756e0e45061855cb3a61f01f6 134 Gene3D G3DSA:3.90.79.10 3 115 2.2E-25 T 11-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 AUP74_RS00445 6e941a9756e0e45061855cb3a61f01f6 134 Pfam PF00293 NUDIX domain 7 111 3.9E-17 T 11-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 AUP74_RS00445 6e941a9756e0e45061855cb3a61f01f6 134 SUPERFAMILY SSF55811 5 113 1.49E-24 T 11-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 AUP74_RS04310 58ee6accca03d7faefde4443f05599a7 289 Pfam PF02678 Pirin 34 127 2.2E-34 T 11-11-2016 IPR003829 Pirin, N-terminal domain AUP74_RS04310 58ee6accca03d7faefde4443f05599a7 289 Pfam PF05726 Pirin C-terminal cupin domain 188 287 4.3E-26 T 11-11-2016 IPR008778 Pirin, C-terminal domain AUP74_RS04310 58ee6accca03d7faefde4443f05599a7 289 SUPERFAMILY SSF51182 15 287 1.78E-73 T 11-11-2016 IPR011051 RmlC-like cupin domain AUP74_RS04310 58ee6accca03d7faefde4443f05599a7 289 PIRSF PIRSF006232 9 289 2.9E-83 T 11-11-2016 IPR012093 Pirin AUP74_RS04310 58ee6accca03d7faefde4443f05599a7 289 Gene3D G3DSA:2.60.120.10 14 261 3.8E-70 T 11-11-2016 IPR014710 RmlC-like jelly roll fold AUP74_RS11780 8be46515f951d2b2c5eee5ebe7418b8b 1626 Gene3D G3DSA:3.40.50.720 951 1062 6.0E-37 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS11780 8be46515f951d2b2c5eee5ebe7418b8b 1626 Gene3D G3DSA:3.40.50.720 1117 1189 6.0E-37 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS11780 8be46515f951d2b2c5eee5ebe7418b8b 1626 SUPERFAMILY SSF53223 763 965 1.34E-26 T 11-11-2016 AUP74_RS11780 8be46515f951d2b2c5eee5ebe7418b8b 1626 PIRSF PIRSF036761 3 1618 0.0 T 11-11-2016 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 AUP74_RS11780 8be46515f951d2b2c5eee5ebe7418b8b 1626 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 76 1611 0.0 T 11-11-2016 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 AUP74_RS11780 8be46515f951d2b2c5eee5ebe7418b8b 1626 SUPERFAMILY SSF51735 1092 1227 9.19E-29 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS11780 8be46515f951d2b2c5eee5ebe7418b8b 1626 SUPERFAMILY SSF51735 954 1056 9.19E-29 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS14875 83bb1db4e9dd94ff17de876c39cf60f9 348 Gene3D G3DSA:3.40.50.2000 155 269 2.2E-10 T 11-11-2016 AUP74_RS14875 83bb1db4e9dd94ff17de876c39cf60f9 348 Pfam PF00534 Glycosyl transferases group 1 167 270 2.7E-13 T 11-11-2016 IPR001296 Glycosyl transferase, family 1 AUP74_RS14875 83bb1db4e9dd94ff17de876c39cf60f9 348 SUPERFAMILY SSF53756 4 331 7.18E-37 T 11-11-2016 AUP74_RS08725 13dc810d560f5e26ad85d70e0354486b 288 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 286 2.9E-153 T 11-11-2016 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 AUP74_RS08725 13dc810d560f5e26ad85d70e0354486b 288 Pfam PF00483 Nucleotidyl transferase 2 237 3.6E-70 T 11-11-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 AUP74_RS08725 13dc810d560f5e26ad85d70e0354486b 288 SUPERFAMILY SSF53448 1 286 9.01E-92 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases AUP74_RS08725 13dc810d560f5e26ad85d70e0354486b 288 Gene3D G3DSA:3.90.550.10 1 262 2.8E-66 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases AUP74_RS07125 511f14356a71022a7c5e9bed0b5e1edf 174 SUPERFAMILY SSF54523 11 91 9.42E-17 T 11-11-2016 AUP74_RS07125 511f14356a71022a7c5e9bed0b5e1edf 174 Gene3D G3DSA:3.30.700.10 11 53 3.9E-8 T 11-11-2016 AUP74_RS07125 511f14356a71022a7c5e9bed0b5e1edf 174 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 9 29 - T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS07125 511f14356a71022a7c5e9bed0b5e1edf 174 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 30 3.5E-8 T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS07125 511f14356a71022a7c5e9bed0b5e1edf 174 Pfam PF12019 Type II transport protein GspH 46 163 1.5E-14 T 11-11-2016 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 AUP74_RS07125 511f14356a71022a7c5e9bed0b5e1edf 174 Pfam PF13633 Prokaryotic N-terminal methylation site 8 33 8.5E-9 T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS10070 9e5854c231d522b09a0fd49a4311f816 281 SUPERFAMILY SSF51569 3 276 1.01E-102 T 11-11-2016 AUP74_RS10070 9e5854c231d522b09a0fd49a4311f816 281 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 16 273 2.7E-116 T 11-11-2016 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 AUP74_RS10070 9e5854c231d522b09a0fd49a4311f816 281 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 11 275 48.923 T 11-11-2016 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 AUP74_RS10070 9e5854c231d522b09a0fd49a4311f816 281 Gene3D G3DSA:3.20.20.70 14 276 9.8E-107 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS10070 9e5854c231d522b09a0fd49a4311f816 281 Pfam PF00793 DAHP synthetase I family 8 272 6.4E-69 T 11-11-2016 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 AUP74_RS15425 acd1b4eacdbba655d5fc3ec70c0ae31d 535 Gene3D G3DSA:1.20.58.100 412 513 1.1E-30 T 11-11-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AUP74_RS15425 acd1b4eacdbba655d5fc3ec70c0ae31d 535 Pfam PF02910 Fumarate reductase flavoprotein C-term 433 513 1.0E-11 T 11-11-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AUP74_RS15425 acd1b4eacdbba655d5fc3ec70c0ae31d 535 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 7 512 1.6E-197 T 11-11-2016 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 AUP74_RS15425 acd1b4eacdbba655d5fc3ec70c0ae31d 535 SUPERFAMILY SSF56425 230 345 4.64E-42 T 11-11-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 AUP74_RS15425 acd1b4eacdbba655d5fc3ec70c0ae31d 535 SUPERFAMILY SSF46977 417 515 5.63E-29 T 11-11-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AUP74_RS15425 acd1b4eacdbba655d5fc3ec70c0ae31d 535 Gene3D G3DSA:3.50.50.60 4 235 8.7E-101 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS15425 acd1b4eacdbba655d5fc3ec70c0ae31d 535 Gene3D G3DSA:3.50.50.60 341 403 8.7E-101 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS15425 acd1b4eacdbba655d5fc3ec70c0ae31d 535 SUPERFAMILY SSF51905 348 440 4.54E-71 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS15425 acd1b4eacdbba655d5fc3ec70c0ae31d 535 SUPERFAMILY SSF51905 5 247 4.54E-71 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS15425 acd1b4eacdbba655d5fc3ec70c0ae31d 535 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 347 369 5.6E-9 T 11-11-2016 AUP74_RS15425 acd1b4eacdbba655d5fc3ec70c0ae31d 535 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 5.6E-9 T 11-11-2016 AUP74_RS15425 acd1b4eacdbba655d5fc3ec70c0ae31d 535 PIRSF PIRSF000171 2 533 6.9E-33 T 11-11-2016 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit Reactome: R-HSA-611105|Reactome: R-HSA-71403 AUP74_RS15425 acd1b4eacdbba655d5fc3ec70c0ae31d 535 Pfam PF00890 FAD binding domain 8 384 1.2E-100 T 11-11-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 AUP74_RS15425 acd1b4eacdbba655d5fc3ec70c0ae31d 535 Gene3D G3DSA:3.90.700.10 236 340 1.9E-38 T 11-11-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 AUP74_RS04095 43a03964f89f72a4f7d99e1586df1553 706 Gene3D G3DSA:3.30.460.10 196 325 4.1E-42 T 11-11-2016 AUP74_RS04095 43a03964f89f72a4f7d99e1586df1553 706 SUPERFAMILY SSF55021 633 703 1.96E-8 T 11-11-2016 AUP74_RS04095 43a03964f89f72a4f7d99e1586df1553 706 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 26 703 2.0E-241 T 11-11-2016 IPR004811 RelA/SpoT family GO:0015969 AUP74_RS04095 43a03964f89f72a4f7d99e1586df1553 706 Pfam PF13291 ACT domain 628 704 1.3E-16 T 11-11-2016 IPR002912 ACT domain GO:0008152|GO:0016597 AUP74_RS04095 43a03964f89f72a4f7d99e1586df1553 706 SUPERFAMILY SSF81301 181 396 9.65E-59 T 11-11-2016 AUP74_RS04095 43a03964f89f72a4f7d99e1586df1553 706 SMART SM00471 41 153 1.9E-9 T 11-11-2016 IPR003607 HD/PDEase domain AUP74_RS04095 43a03964f89f72a4f7d99e1586df1553 706 Gene3D G3DSA:3.30.70.260 633 702 8.8E-11 T 11-11-2016 AUP74_RS04095 43a03964f89f72a4f7d99e1586df1553 706 SUPERFAMILY SSF81271 379 452 8.94E-21 T 11-11-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 AUP74_RS04095 43a03964f89f72a4f7d99e1586df1553 706 SMART SM00954 235 345 1.2E-58 T 11-11-2016 IPR007685 RelA/SpoT GO:0015969 AUP74_RS04095 43a03964f89f72a4f7d99e1586df1553 706 Pfam PF13328 HD domain 26 175 3.3E-53 T 11-11-2016 IPR003607 HD/PDEase domain AUP74_RS04095 43a03964f89f72a4f7d99e1586df1553 706 SUPERFAMILY SSF109604 4 189 2.2E-71 T 11-11-2016 AUP74_RS04095 43a03964f89f72a4f7d99e1586df1553 706 Pfam PF04607 Region found in RelA / SpoT proteins 235 344 2.7E-35 T 11-11-2016 IPR007685 RelA/SpoT GO:0015969 AUP74_RS04095 43a03964f89f72a4f7d99e1586df1553 706 Gene3D G3DSA:3.10.20.30 391 453 6.7E-23 T 11-11-2016 IPR012675 Beta-grasp domain AUP74_RS04095 43a03964f89f72a4f7d99e1586df1553 706 Pfam PF02824 TGS domain 392 451 4.9E-19 T 11-11-2016 IPR004095 TGS KEGG: 00970+6.1.1.3 AUP74_RS04505 7639781035a43f5801408079d28d7085 391 SUPERFAMILY SSF53335 81 387 3.56E-68 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS04505 7639781035a43f5801408079d28d7085 391 Gene3D G3DSA:3.30.750.80 74 177 7.0E-29 T 11-11-2016 AUP74_RS04505 7639781035a43f5801408079d28d7085 391 SUPERFAMILY SSF88697 3 71 3.23E-11 T 11-11-2016 IPR015947 PUA-like domain AUP74_RS04505 7639781035a43f5801408079d28d7085 391 Gene3D G3DSA:3.40.50.150 181 388 1.2E-56 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS04505 7639781035a43f5801408079d28d7085 391 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 112 348 4.9E-17 T 11-11-2016 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 AUP74_RS04505 7639781035a43f5801408079d28d7085 391 Gene3D G3DSA:2.30.130.10 3 70 1.1E-14 T 11-11-2016 IPR015947 PUA-like domain AUP74_RS10765 0ebd9d56bba5d245c203968e8b24d335 419 PRINTS PR00762 Chloride channel signature 97 116 8.4E-23 T 11-11-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AUP74_RS10765 0ebd9d56bba5d245c203968e8b24d335 419 PRINTS PR00762 Chloride channel signature 148 167 8.4E-23 T 11-11-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AUP74_RS10765 0ebd9d56bba5d245c203968e8b24d335 419 PRINTS PR00762 Chloride channel signature 364 383 8.4E-23 T 11-11-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AUP74_RS10765 0ebd9d56bba5d245c203968e8b24d335 419 PRINTS PR00762 Chloride channel signature 311 331 8.4E-23 T 11-11-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AUP74_RS10765 0ebd9d56bba5d245c203968e8b24d335 419 PRINTS PR00762 Chloride channel signature 346 362 8.4E-23 T 11-11-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AUP74_RS10765 0ebd9d56bba5d245c203968e8b24d335 419 Gene3D G3DSA:1.10.3080.10 2 405 9.2E-64 T 11-11-2016 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 AUP74_RS10765 0ebd9d56bba5d245c203968e8b24d335 419 Pfam PF00654 Voltage gated chloride channel 57 396 3.3E-54 T 11-11-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AUP74_RS10765 0ebd9d56bba5d245c203968e8b24d335 419 SUPERFAMILY SSF81340 4 407 7.06E-68 T 11-11-2016 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 AUP74_RS08775 b9ae876e5db7c5328f26ab22471691e4 409 SUPERFAMILY SSF56935 73 312 1.12E-5 T 11-11-2016 AUP74_RS08775 b9ae876e5db7c5328f26ab22471691e4 409 Pfam PF10082 Putative beta-barrel porin 2 39 407 4.9E-37 T 11-11-2016 IPR018759 Putative beta-barrel porin 2 AUP74_RS14520 5d73720898b85e61653bfbebf26cab17 273 Gene3D G3DSA:3.40.50.1820 10 266 1.8E-40 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS14520 5d73720898b85e61653bfbebf26cab17 273 Pfam PF00561 alpha/beta hydrolase fold 32 141 3.8E-14 T 11-11-2016 IPR000073 Alpha/beta hydrolase fold-1 AUP74_RS14520 5d73720898b85e61653bfbebf26cab17 273 SUPERFAMILY SSF53474 10 266 1.25E-41 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS14520 5d73720898b85e61653bfbebf26cab17 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 101 114 6.3E-6 T 11-11-2016 IPR000073 Alpha/beta hydrolase fold-1 AUP74_RS14520 5d73720898b85e61653bfbebf26cab17 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 115 128 6.3E-6 T 11-11-2016 IPR000073 Alpha/beta hydrolase fold-1 AUP74_RS14520 5d73720898b85e61653bfbebf26cab17 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 57 72 6.3E-6 T 11-11-2016 IPR000073 Alpha/beta hydrolase fold-1 AUP74_RS15040 1e70d51948b65a482ce19173216cb32a 357 Gene3D G3DSA:3.40.50.720 153 336 1.0E-51 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS15040 1e70d51948b65a482ce19173216cb32a 357 PIRSF PIRSF000188 1 354 2.8E-147 T 11-11-2016 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 AUP74_RS15040 1e70d51948b65a482ce19173216cb32a 357 Gene3D G3DSA:3.40.192.10 1 152 9.1E-65 T 11-11-2016 AUP74_RS15040 1e70d51948b65a482ce19173216cb32a 357 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 176 196 1.1E-14 T 11-11-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 AUP74_RS15040 1e70d51948b65a482ce19173216cb32a 357 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 286 297 1.1E-14 T 11-11-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 AUP74_RS15040 1e70d51948b65a482ce19173216cb32a 357 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 66 80 1.1E-14 T 11-11-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 AUP74_RS15040 1e70d51948b65a482ce19173216cb32a 357 SUPERFAMILY SSF51735 144 344 1.82E-50 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS15040 1e70d51948b65a482ce19173216cb32a 357 SUPERFAMILY SSF53223 7 136 8.32E-42 T 11-11-2016 AUP74_RS15040 1e70d51948b65a482ce19173216cb32a 357 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 221 331 3.1E-9 T 11-11-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 AUP74_RS15040 1e70d51948b65a482ce19173216cb32a 357 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 21 130 1.2E-25 T 11-11-2016 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 AUP74_RS15040 1e70d51948b65a482ce19173216cb32a 357 SMART SM00839 144 352 2.6E-71 T 11-11-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 AUP74_RS15040 1e70d51948b65a482ce19173216cb32a 357 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 74 87 - T 11-11-2016 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-70614 AUP74_RS04335 5dc6b20845d0a545b503b95b7509058f 256 SUPERFAMILY SSF46785 7 64 7.46E-14 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS04335 5dc6b20845d0a545b503b95b7509058f 256 SMART SM01134 70 231 1.0E-61 T 11-11-2016 AUP74_RS04335 5dc6b20845d0a545b503b95b7509058f 256 Pfam PF08220 DeoR-like helix-turn-helix domain 9 60 7.0E-15 T 11-11-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AUP74_RS04335 5dc6b20845d0a545b503b95b7509058f 256 Gene3D G3DSA:3.40.50.1360 81 221 5.2E-17 T 11-11-2016 AUP74_RS04335 5dc6b20845d0a545b503b95b7509058f 256 SMART SM00420 9 61 1.9E-11 T 11-11-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AUP74_RS04335 5dc6b20845d0a545b503b95b7509058f 256 SUPERFAMILY SSF100950 74 231 5.5E-33 T 11-11-2016 AUP74_RS04335 5dc6b20845d0a545b503b95b7509058f 256 Gene3D G3DSA:1.10.10.10 7 80 7.9E-11 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS04335 5dc6b20845d0a545b503b95b7509058f 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 41 59 9.0E-8 T 11-11-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AUP74_RS04335 5dc6b20845d0a545b503b95b7509058f 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 27 41 9.0E-8 T 11-11-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AUP74_RS04335 5dc6b20845d0a545b503b95b7509058f 256 ProSitePatterns PS00894 DeoR-type HTH domain signature. 9 43 - T 11-11-2016 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 AUP74_RS04335 5dc6b20845d0a545b503b95b7509058f 256 Pfam PF00455 DeoR C terminal sensor domain 74 229 8.9E-44 T 11-11-2016 IPR014036 DeoR C-terminal sensor domain AUP74_RS08420 d259057e612d3ad38b4ed38642637316 221 Pfam PF01467 Cytidylyltransferase-like 10 187 8.3E-29 T 11-11-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AUP74_RS08420 d259057e612d3ad38b4ed38642637316 221 Gene3D G3DSA:3.40.50.620 7 216 2.4E-66 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS08420 d259057e612d3ad38b4ed38642637316 221 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 8 68 1.2E-10 T 11-11-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AUP74_RS08420 d259057e612d3ad38b4ed38642637316 221 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 6 214 30.354 T 11-11-2016 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 AUP74_RS08420 d259057e612d3ad38b4ed38642637316 221 SUPERFAMILY SSF52374 6 216 1.41E-53 T 11-11-2016 AUP74_RS08420 d259057e612d3ad38b4ed38642637316 221 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 10 213 6.7E-49 T 11-11-2016 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 AUP74_RS12815 c74ab72c4b2d78421e669bdd13ebde49 239 PIRSF PIRSF037208 1 239 2.0E-91 T 11-11-2016 IPR017138 Putative arginyl-tRNA--protein transferase, prokaryotic AUP74_RS12815 c74ab72c4b2d78421e669bdd13ebde49 239 Pfam PF04377 Arginine-tRNA-protein transferase, C terminus 108 229 1.2E-39 T 11-11-2016 IPR007472 Arginine-tRNA-protein transferase, C-terminal GO:0004057|GO:0016598 AUP74_RS12815 c74ab72c4b2d78421e669bdd13ebde49 239 Pfam PF04376 Arginine-tRNA-protein transferase, N terminus 18 88 2.0E-18 T 11-11-2016 IPR007471 Arginine-tRNA-protein transferase, N-terminal GO:0004057|GO:0016598 AUP74_RS12815 c74ab72c4b2d78421e669bdd13ebde49 239 SUPERFAMILY SSF55729 83 234 2.28E-30 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS12815 c74ab72c4b2d78421e669bdd13ebde49 239 Hamap MF_00689 Putative arginyl-tRNA--protein transferase [ate]. 3 238 44.173 T 11-11-2016 IPR017138 Putative arginyl-tRNA--protein transferase, prokaryotic AUP74_RS12815 c74ab72c4b2d78421e669bdd13ebde49 239 Gene3D G3DSA:3.40.630.30 105 212 7.5E-4 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS16020 6088fc896d16dad76d531ece0aa7af28 585 SUPERFAMILY SSF51011 506 583 2.96E-12 T 11-11-2016 AUP74_RS16020 6088fc896d16dad76d531ece0aa7af28 585 Pfam PF00128 Alpha amylase, catalytic domain 94 351 2.6E-23 T 11-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AUP74_RS16020 6088fc896d16dad76d531ece0aa7af28 585 SUPERFAMILY SSF51445 414 501 1.42E-92 T 11-11-2016 IPR017853 Glycoside hydrolase superfamily AUP74_RS16020 6088fc896d16dad76d531ece0aa7af28 585 SUPERFAMILY SSF51445 39 378 1.42E-92 T 11-11-2016 IPR017853 Glycoside hydrolase superfamily AUP74_RS16020 6088fc896d16dad76d531ece0aa7af28 585 SMART SM00642 63 494 8.3E-8 T 11-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AUP74_RS16020 6088fc896d16dad76d531ece0aa7af28 585 Gene3D G3DSA:2.60.40.1180 513 583 2.9E-18 T 11-11-2016 IPR013780 Glycosyl hydrolase, all-beta AUP74_RS16020 6088fc896d16dad76d531ece0aa7af28 585 Gene3D G3DSA:3.20.20.80 223 496 1.6E-107 T 11-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 AUP74_RS16020 6088fc896d16dad76d531ece0aa7af28 585 Gene3D G3DSA:3.20.20.80 61 148 1.6E-107 T 11-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 AUP74_RS16020 6088fc896d16dad76d531ece0aa7af28 585 Gene3D G3DSA:3.90.400.10 149 217 4.7E-19 T 11-11-2016 AUP74_RS16020 6088fc896d16dad76d531ece0aa7af28 585 PIRSF PIRSF003059 16 583 2.1E-179 T 11-11-2016 IPR016377 Sucrose phosphorylase GO:0005985|GO:0009018 KEGG: 00500+2.4.1.7|MetaCyc: PWY-5384 AUP74_RS05475 12d8e1d48ef8bf6d35b6eedf78ebef40 362 Pfam PF06580 Histidine kinase 158 235 5.7E-24 T 11-11-2016 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 AUP74_RS05475 12d8e1d48ef8bf6d35b6eedf78ebef40 362 SUPERFAMILY SSF55874 210 344 3.34E-10 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS05475 12d8e1d48ef8bf6d35b6eedf78ebef40 362 Gene3D G3DSA:3.30.565.10 207 345 1.5E-8 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS04885 6c483b5da1205534d28f5309011b6aa0 258 SUPERFAMILY SSF63380 7 100 5.91E-24 T 11-11-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 AUP74_RS04885 6c483b5da1205534d28f5309011b6aa0 258 SUPERFAMILY SSF52343 104 252 1.83E-40 T 11-11-2016 AUP74_RS04885 6c483b5da1205534d28f5309011b6aa0 258 Gene3D G3DSA:3.40.50.80 99 257 1.0E-45 T 11-11-2016 AUP74_RS04885 6c483b5da1205534d28f5309011b6aa0 258 Gene3D G3DSA:2.40.30.10 8 98 2.1E-29 T 11-11-2016 AUP74_RS04885 6c483b5da1205534d28f5309011b6aa0 258 Pfam PF00175 Oxidoreductase NAD-binding domain 113 228 2.4E-9 T 11-11-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AUP74_RS04885 6c483b5da1205534d28f5309011b6aa0 258 Pfam PF00970 Oxidoreductase FAD-binding domain 16 98 4.8E-6 T 11-11-2016 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 AUP74_RS06380 195d1417df603efc514662049db30483 526 Pfam PF04293 SpoVR like protein 22 453 2.2E-176 T 11-11-2016 IPR007390 Sporulation stage V, protein R AUP74_RS00865 3c2a15eafbcb200f8a6f7e0afedadded 92 SUPERFAMILY SSF64307 15 89 8.5E-20 T 11-11-2016 IPR001455 TusA-like domain AUP74_RS00865 3c2a15eafbcb200f8a6f7e0afedadded 92 Pfam PF01206 Sulfurtransferase TusA 22 89 4.3E-17 T 11-11-2016 IPR001455 TusA-like domain AUP74_RS00865 3c2a15eafbcb200f8a6f7e0afedadded 92 Gene3D G3DSA:3.30.110.40 17 89 5.0E-21 T 11-11-2016 IPR001455 TusA-like domain AUP74_RS02670 2285e62a829f19b1b7965c3cf2f8286e 834 Gene3D G3DSA:1.10.390.10 291 438 1.3E-44 T 11-11-2016 AUP74_RS02670 2285e62a829f19b1b7965c3cf2f8286e 834 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 1 826 4.6E-243 T 11-11-2016 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 AUP74_RS02670 2285e62a829f19b1b7965c3cf2f8286e 834 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 117 132 1.4E-16 T 11-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AUP74_RS02670 2285e62a829f19b1b7965c3cf2f8286e 834 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 165 180 1.4E-16 T 11-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AUP74_RS02670 2285e62a829f19b1b7965c3cf2f8286e 834 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 278 293 1.4E-16 T 11-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AUP74_RS02670 2285e62a829f19b1b7965c3cf2f8286e 834 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 244 254 1.4E-16 T 11-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AUP74_RS02670 2285e62a829f19b1b7965c3cf2f8286e 834 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 297 309 1.4E-16 T 11-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AUP74_RS02670 2285e62a829f19b1b7965c3cf2f8286e 834 Pfam PF01433 Peptidase family M1 4 370 2.7E-79 T 11-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AUP74_RS02670 2285e62a829f19b1b7965c3cf2f8286e 834 SUPERFAMILY SSF55486 189 436 3.42E-76 T 11-11-2016 AUP74_RS02670 2285e62a829f19b1b7965c3cf2f8286e 834 Pfam PF11838 ERAP1-like C-terminal domain 509 815 1.8E-27 T 11-11-2016 IPR024571 ERAP1-like C-terminal domain AUP74_RS02670 2285e62a829f19b1b7965c3cf2f8286e 834 SUPERFAMILY SSF63737 6 182 1.26E-38 T 11-11-2016 AUP74_RS13270 ee5910a49e21b83c2decd5fd808ff09e 553 Gene3D G3DSA:3.30.413.10 409 549 4.0E-35 T 11-11-2016 AUP74_RS13270 ee5910a49e21b83c2decd5fd808ff09e 553 Gene3D G3DSA:3.30.413.10 120 274 2.4E-43 T 11-11-2016 AUP74_RS13270 ee5910a49e21b83c2decd5fd808ff09e 553 SUPERFAMILY SSF55124 1 125 2.62E-27 T 11-11-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AUP74_RS13270 ee5910a49e21b83c2decd5fd808ff09e 553 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 119 272 4.9E-44 T 11-11-2016 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AUP74_RS13270 ee5910a49e21b83c2decd5fd808ff09e 553 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 413 549 2.0E-11 T 11-11-2016 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AUP74_RS13270 ee5910a49e21b83c2decd5fd808ff09e 553 SUPERFAMILY SSF56014 409 551 3.01E-40 T 11-11-2016 AUP74_RS13270 ee5910a49e21b83c2decd5fd808ff09e 553 SUPERFAMILY SSF55124 251 275 1.52E-21 T 11-11-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AUP74_RS13270 ee5910a49e21b83c2decd5fd808ff09e 553 SUPERFAMILY SSF55124 316 422 1.52E-21 T 11-11-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AUP74_RS13270 ee5910a49e21b83c2decd5fd808ff09e 553 SUPERFAMILY SSF56014 120 278 2.88E-49 T 11-11-2016 AUP74_RS13270 ee5910a49e21b83c2decd5fd808ff09e 553 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 347 399 1.6E-12 T 11-11-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AUP74_RS13270 ee5910a49e21b83c2decd5fd808ff09e 553 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 53 111 1.9E-17 T 11-11-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AUP74_RS13270 ee5910a49e21b83c2decd5fd808ff09e 553 Gene3D G3DSA:3.90.480.10 52 117 1.8E-34 T 11-11-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AUP74_RS13270 ee5910a49e21b83c2decd5fd808ff09e 553 Gene3D G3DSA:3.90.480.10 322 404 1.8E-34 T 11-11-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AUP74_RS04940 3ec13275b3196acc76058b0b3063ee8c 460 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 171 420 4.3E-66 T 11-11-2016 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 AUP74_RS04940 3ec13275b3196acc76058b0b3063ee8c 460 PIRSF PIRSF005943 1 460 6.5E-183 T 11-11-2016 IPR016471 Nicotinamide phosphoribosyl transferase Reactome: R-HSA-1368108|Reactome: R-HSA-197264 AUP74_RS04940 3ec13275b3196acc76058b0b3063ee8c 460 SUPERFAMILY SSF51690 140 459 1.84E-42 T 11-11-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 AUP74_RS04940 3ec13275b3196acc76058b0b3063ee8c 460 Gene3D G3DSA:3.20.140.10 127 396 6.7E-7 T 11-11-2016 AUP74_RS11145 400e83167172a66b83b999a754adb6c1 119 Gene3D G3DSA:3.30.160.100 8 103 5.0E-15 T 11-11-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 AUP74_RS11145 400e83167172a66b83b999a754adb6c1 119 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 8 102 8.5E-12 T 11-11-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 AUP74_RS11145 400e83167172a66b83b999a754adb6c1 119 SUPERFAMILY SSF69754 8 113 9.68E-17 T 11-11-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 AUP74_RS13735 7e404c7bf288b2522cb10341705feb8c 416 Pfam PF01593 Flavin containing amine oxidoreductase 10 302 2.1E-21 T 11-11-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 AUP74_RS13735 7e404c7bf288b2522cb10341705feb8c 416 Gene3D G3DSA:3.50.50.60 1 110 5.4E-33 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS13735 7e404c7bf288b2522cb10341705feb8c 416 Gene3D G3DSA:3.50.50.60 201 301 5.4E-33 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS13735 7e404c7bf288b2522cb10341705feb8c 416 SUPERFAMILY SSF51905 1 301 1.42E-54 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS13735 7e404c7bf288b2522cb10341705feb8c 416 SUPERFAMILY SSF51905 381 412 1.42E-54 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS05750 4a7d2d24a7fc926a5f0199c477221657 164 Gene3D G3DSA:3.40.50.300 1 159 8.8E-49 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05750 4a7d2d24a7fc926a5f0199c477221657 164 Pfam PF01202 Shikimate kinase 1 157 7.2E-52 T 11-11-2016 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 AUP74_RS05750 4a7d2d24a7fc926a5f0199c477221657 164 SUPERFAMILY SSF52540 1 157 8.75E-27 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05750 4a7d2d24a7fc926a5f0199c477221657 164 Hamap MF_00109 Shikimate kinase [aroK]. 1 158 24.927 T 11-11-2016 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 AUP74_RS05750 4a7d2d24a7fc926a5f0199c477221657 164 PRINTS PR01100 Shikimate kinase family signature 47 55 1.5E-17 T 11-11-2016 AUP74_RS05750 4a7d2d24a7fc926a5f0199c477221657 164 PRINTS PR01100 Shikimate kinase family signature 65 74 1.5E-17 T 11-11-2016 AUP74_RS05750 4a7d2d24a7fc926a5f0199c477221657 164 PRINTS PR01100 Shikimate kinase family signature 86 103 1.5E-17 T 11-11-2016 AUP74_RS05750 4a7d2d24a7fc926a5f0199c477221657 164 PRINTS PR01100 Shikimate kinase family signature 19 32 1.5E-17 T 11-11-2016 AUP74_RS05750 4a7d2d24a7fc926a5f0199c477221657 164 ProSitePatterns PS01128 Shikimate kinase signature. 48 73 - T 11-11-2016 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 AUP74_RS16255 f89c1fbf03e434d33e10ec2136c7b8f3 967 Pfam PF00593 TonB dependent receptor 685 966 4.6E-28 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS16255 f89c1fbf03e434d33e10ec2136c7b8f3 967 SUPERFAMILY SSF56935 27 225 5.31E-72 T 11-11-2016 AUP74_RS16255 f89c1fbf03e434d33e10ec2136c7b8f3 967 SUPERFAMILY SSF56935 281 417 5.31E-72 T 11-11-2016 AUP74_RS16255 f89c1fbf03e434d33e10ec2136c7b8f3 967 SUPERFAMILY SSF56935 455 518 5.31E-72 T 11-11-2016 AUP74_RS16255 f89c1fbf03e434d33e10ec2136c7b8f3 967 SUPERFAMILY SSF56935 588 967 5.31E-72 T 11-11-2016 AUP74_RS16255 f89c1fbf03e434d33e10ec2136c7b8f3 967 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 38 967 4.5E-175 T 11-11-2016 IPR010104 Bacterial TonB-dependent receptor AUP74_RS16255 f89c1fbf03e434d33e10ec2136c7b8f3 967 Gene3D G3DSA:2.40.170.20 475 513 1.4E-50 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS16255 f89c1fbf03e434d33e10ec2136c7b8f3 967 Gene3D G3DSA:2.40.170.20 551 552 1.4E-50 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS16255 f89c1fbf03e434d33e10ec2136c7b8f3 967 Gene3D G3DSA:2.40.170.20 361 430 1.4E-50 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS16255 f89c1fbf03e434d33e10ec2136c7b8f3 967 Gene3D G3DSA:2.40.170.20 590 967 1.4E-50 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS16255 f89c1fbf03e434d33e10ec2136c7b8f3 967 Gene3D G3DSA:2.40.170.20 164 323 1.4E-50 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS16255 f89c1fbf03e434d33e10ec2136c7b8f3 967 Pfam PF07715 TonB-dependent Receptor Plug Domain 56 154 3.0E-9 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS16255 f89c1fbf03e434d33e10ec2136c7b8f3 967 Gene3D G3DSA:2.170.130.10 57 163 4.6E-14 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS13170 42bfc2da92bf2d7c2e9d6094a77a17ad 91 Gene3D G3DSA:3.40.1260.10 1 88 1.7E-24 T 11-11-2016 IPR027396 DsrEFH-like AUP74_RS13170 42bfc2da92bf2d7c2e9d6094a77a17ad 91 SUPERFAMILY SSF75169 3 90 2.5E-20 T 11-11-2016 IPR027396 DsrEFH-like AUP74_RS13170 42bfc2da92bf2d7c2e9d6094a77a17ad 91 TIGRFAM TIGR03011 sulf_tusB_dsrH: sulfur relay protein TusB/DsrH 3 90 1.3E-22 T 11-11-2016 IPR007215 Sulphur relay, TusB/DsrH GO:0002143|GO:0005737 AUP74_RS13170 42bfc2da92bf2d7c2e9d6094a77a17ad 91 Pfam PF04077 DsrH like protein 9 85 2.5E-19 T 11-11-2016 IPR007215 Sulphur relay, TusB/DsrH GO:0002143|GO:0005737 AUP74_RS00130 36960145849916900714213d1d80f1a5 519 Pfam PF00270 DEAD/DEAH box helicase 131 305 1.4E-47 T 11-11-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AUP74_RS00130 36960145849916900714213d1d80f1a5 519 SMART SM00487 125 332 1.1E-51 T 11-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain AUP74_RS00130 36960145849916900714213d1d80f1a5 519 Pfam PF00271 Helicase conserved C-terminal domain 340 449 5.6E-28 T 11-11-2016 IPR001650 Helicase, C-terminal AUP74_RS00130 36960145849916900714213d1d80f1a5 519 Hamap MF_00661 ATP-dependent RNA helicase RhlB [rhlB]. 105 487 51.397 T 11-11-2016 IPR023554 ATP-dependent RNA helicase RhlB type GO:0004004 AUP74_RS00130 36960145849916900714213d1d80f1a5 519 SMART SM00490 368 449 1.1E-30 T 11-11-2016 IPR001650 Helicase, C-terminal AUP74_RS00130 36960145849916900714213d1d80f1a5 519 SUPERFAMILY SSF52540 182 467 1.44E-72 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS00130 36960145849916900714213d1d80f1a5 519 Gene3D G3DSA:3.40.50.300 324 482 3.9E-48 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS00130 36960145849916900714213d1d80f1a5 519 Gene3D G3DSA:3.40.50.300 105 323 6.3E-77 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS00130 36960145849916900714213d1d80f1a5 519 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 261 269 - T 11-11-2016 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site AUP74_RS16080 be27e0ebefca1f9b7a6800dd2c6d7388 405 Gene3D G3DSA:3.40.50.1100 110 187 4.1E-22 T 11-11-2016 AUP74_RS16080 be27e0ebefca1f9b7a6800dd2c6d7388 405 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 12 401 52.876 T 11-11-2016 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AUP74_RS16080 be27e0ebefca1f9b7a6800dd2c6d7388 405 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 91 105 - T 11-11-2016 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AUP74_RS16080 be27e0ebefca1f9b7a6800dd2c6d7388 405 Gene3D G3DSA:3.40.50.1100 188 400 3.1E-97 T 11-11-2016 AUP74_RS16080 be27e0ebefca1f9b7a6800dd2c6d7388 405 PIRSF PIRSF001413 2 405 2.5E-164 T 11-11-2016 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AUP74_RS16080 be27e0ebefca1f9b7a6800dd2c6d7388 405 SUPERFAMILY SSF53686 13 398 8.64E-149 T 11-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme AUP74_RS16080 be27e0ebefca1f9b7a6800dd2c6d7388 405 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 64 388 2.7E-49 T 11-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme AUP74_RS16080 be27e0ebefca1f9b7a6800dd2c6d7388 405 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 17 399 1.1E-187 T 11-11-2016 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AUP74_RS10795 535294fd7a671e7d49e1a86a6d92c687 201 Pfam PF01914 MarC family integral membrane protein 3 198 3.7E-24 T 11-11-2016 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 AUP74_RS05645 67ee73a884c9717b07d7c57d323bf29d 750 Gene3D G3DSA:2.170.130.10 30 167 1.0E-27 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS05645 67ee73a884c9717b07d7c57d323bf29d 750 SUPERFAMILY SSF56935 30 750 1.44E-102 T 11-11-2016 AUP74_RS05645 67ee73a884c9717b07d7c57d323bf29d 750 Gene3D G3DSA:2.40.170.20 184 750 9.9E-71 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS05645 67ee73a884c9717b07d7c57d323bf29d 750 Pfam PF00593 TonB dependent receptor 496 748 3.4E-23 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS05645 67ee73a884c9717b07d7c57d323bf29d 750 Pfam PF07715 TonB-dependent Receptor Plug Domain 49 157 7.5E-13 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS04440 db6b6b92a0aee854dece8d61a4dfb141 217 Gene3D G3DSA:3.40.50.150 6 211 1.1E-62 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS04440 db6b6b92a0aee854dece8d61a4dfb141 217 SUPERFAMILY SSF53335 11 209 1.69E-38 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS04440 db6b6b92a0aee854dece8d61a4dfb141 217 PIRSF PIRSF003078 1 212 2.3E-57 T 11-11-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 AUP74_RS04440 db6b6b92a0aee854dece8d61a4dfb141 217 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 28 208 1.9E-53 T 11-11-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 AUP74_RS04440 db6b6b92a0aee854dece8d61a4dfb141 217 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 16 206 26.943 T 11-11-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 AUP74_RS04440 db6b6b92a0aee854dece8d61a4dfb141 217 Pfam PF02527 rRNA small subunit methyltransferase G 24 205 4.2E-56 T 11-11-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 AUP74_RS04275 efa7dc3201a8e56f5349fde671199a68 731 Pfam PF00580 UvrD/REP helicase N-terminal domain 10 271 2.4E-73 T 11-11-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 AUP74_RS04275 efa7dc3201a8e56f5349fde671199a68 731 Gene3D G3DSA:3.40.50.300 286 387 1.8E-73 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04275 efa7dc3201a8e56f5349fde671199a68 731 Gene3D G3DSA:3.40.50.300 555 645 1.8E-73 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04275 efa7dc3201a8e56f5349fde671199a68 731 SUPERFAMILY SSF52540 4 645 5.21E-179 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04275 efa7dc3201a8e56f5349fde671199a68 731 Gene3D G3DSA:1.10.486.10 388 543 7.1E-48 T 11-11-2016 AUP74_RS04275 efa7dc3201a8e56f5349fde671199a68 731 Gene3D G3DSA:3.40.50.300 191 285 8.4E-71 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04275 efa7dc3201a8e56f5349fde671199a68 731 Gene3D G3DSA:3.40.50.300 3 110 8.4E-71 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04275 efa7dc3201a8e56f5349fde671199a68 731 Pfam PF13361 UvrD-like helicase C-terminal domain 277 619 2.9E-76 T 11-11-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 AUP74_RS04275 efa7dc3201a8e56f5349fde671199a68 731 Gene3D G3DSA:1.10.10.160 114 190 8.6E-20 T 11-11-2016 IPR013986 DExx box DNA helicase domain AUP74_RS16865 adb98d0a57f001bfde0680441ef91e10 130 SUPERFAMILY SSF54211 5 130 4.93E-47 T 11-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold AUP74_RS16865 adb98d0a57f001bfde0680441ef91e10 130 Gene3D G3DSA:3.30.230.10 5 130 7.6E-50 T 11-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AUP74_RS16865 adb98d0a57f001bfde0680441ef91e10 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 1.6E-46 T 11-11-2016 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 AUP74_RS16865 adb98d0a57f001bfde0680441ef91e10 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 32.421 T 11-11-2016 IPR023035 Ribosomal protein S9, bacterial/plastid AUP74_RS16865 adb98d0a57f001bfde0680441ef91e10 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 11-11-2016 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 AUP74_RS00935 2cec2e9eb946ac0f80496f3188af52f9 338 Gene3D G3DSA:1.10.8.60 189 261 3.9E-34 T 11-11-2016 AUP74_RS00935 2cec2e9eb946ac0f80496f3188af52f9 338 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 338 183.659 T 11-11-2016 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 AUP74_RS00935 2cec2e9eb946ac0f80496f3188af52f9 338 SMART SM00382 57 184 3.9E-12 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS00935 2cec2e9eb946ac0f80496f3188af52f9 338 SUPERFAMILY SSF52540 26 257 5.14E-54 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS00935 2cec2e9eb946ac0f80496f3188af52f9 338 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 17 241 3.3E-116 T 11-11-2016 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 AUP74_RS00935 2cec2e9eb946ac0f80496f3188af52f9 338 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 29 333 1.1E-147 T 11-11-2016 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 AUP74_RS00935 2cec2e9eb946ac0f80496f3188af52f9 338 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 259 332 6.9E-34 T 11-11-2016 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 AUP74_RS00935 2cec2e9eb946ac0f80496f3188af52f9 338 Gene3D G3DSA:1.10.10.10 263 334 2.9E-35 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS00935 2cec2e9eb946ac0f80496f3188af52f9 338 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 256 338 6.0E-30 T 11-11-2016 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 AUP74_RS00935 2cec2e9eb946ac0f80496f3188af52f9 338 Gene3D G3DSA:3.40.50.300 26 181 1.7E-30 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS00935 2cec2e9eb946ac0f80496f3188af52f9 338 SUPERFAMILY SSF46785 263 336 1.85E-25 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS12240 3a6515104957fbe294ba2d8e2a6a2faf 188 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 47 69 - T 11-11-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AUP74_RS12240 3a6515104957fbe294ba2d8e2a6a2faf 188 PIRSF PIRSF000847 1 187 6.6E-47 T 11-11-2016 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 AUP74_RS12240 3a6515104957fbe294ba2d8e2a6a2faf 188 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 2 180 8.9E-54 T 11-11-2016 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 AUP74_RS12240 3a6515104957fbe294ba2d8e2a6a2faf 188 Pfam PF01066 CDP-alcohol phosphatidyltransferase 3 69 3.6E-17 T 11-11-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AUP74_RS01480 263bbc4cde8e031c6ca65a22723d89cc 497 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 420 483 7.2E-7 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS01480 263bbc4cde8e031c6ca65a22723d89cc 497 Gene3D G3DSA:1.10.760.10 434 485 4.1E-7 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS01480 263bbc4cde8e031c6ca65a22723d89cc 497 SUPERFAMILY SSF50952 48 403 7.06E-37 T 11-11-2016 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 AUP74_RS01480 263bbc4cde8e031c6ca65a22723d89cc 497 Gene3D G3DSA:2.120.10.30 47 392 4.7E-61 T 11-11-2016 IPR011042 Six-bladed beta-propeller, TolB-like AUP74_RS01480 263bbc4cde8e031c6ca65a22723d89cc 497 Pfam PF07995 Glucose / Sorbosone dehydrogenase 63 318 4.8E-15 T 11-11-2016 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 AUP74_RS01480 263bbc4cde8e031c6ca65a22723d89cc 497 Gene3D G3DSA:1.10.760.10 401 433 8.7E-4 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS01480 263bbc4cde8e031c6ca65a22723d89cc 497 SUPERFAMILY SSF46626 406 487 3.78E-12 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS01010 12692f135abb88a1fe074fcf22255ab0 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.9E-34 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS01010 12692f135abb88a1fe074fcf22255ab0 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 1.9E-34 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS01010 12692f135abb88a1fe074fcf22255ab0 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 1.9E-34 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS01010 12692f135abb88a1fe074fcf22255ab0 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.9E-34 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS01010 12692f135abb88a1fe074fcf22255ab0 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.9E-34 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS01010 12692f135abb88a1fe074fcf22255ab0 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.9E-34 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS01010 12692f135abb88a1fe074fcf22255ab0 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 11-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AUP74_RS01010 12692f135abb88a1fe074fcf22255ab0 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 4.0E-11 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS01010 12692f135abb88a1fe074fcf22255ab0 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 4.0E-11 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS01010 12692f135abb88a1fe074fcf22255ab0 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 4.0E-11 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS01010 12692f135abb88a1fe074fcf22255ab0 255 SUPERFAMILY SSF51735 4 244 4.37E-71 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS01010 12692f135abb88a1fe074fcf22255ab0 255 Gene3D G3DSA:3.40.50.720 2 244 3.4E-75 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS01010 12692f135abb88a1fe074fcf22255ab0 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 244 7.9E-57 T 11-11-2016 AUP74_RS12890 3c39dc53451c72a626ee83c5f4b47e83 311 SUPERFAMILY SSF46785 3 85 5.16E-20 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS12890 3c39dc53451c72a626ee83c5f4b47e83 311 Gene3D G3DSA:3.40.190.10 172 279 4.3E-24 T 11-11-2016 AUP74_RS12890 3c39dc53451c72a626ee83c5f4b47e83 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 2.9E-16 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS12890 3c39dc53451c72a626ee83c5f4b47e83 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 6.8E-6 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS12890 3c39dc53451c72a626ee83c5f4b47e83 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 6.8E-6 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS12890 3c39dc53451c72a626ee83c5f4b47e83 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 6.8E-6 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS12890 3c39dc53451c72a626ee83c5f4b47e83 311 Gene3D G3DSA:3.40.190.10 283 310 2.7E-29 T 11-11-2016 AUP74_RS12890 3c39dc53451c72a626ee83c5f4b47e83 311 Gene3D G3DSA:3.40.190.10 90 171 2.7E-29 T 11-11-2016 AUP74_RS12890 3c39dc53451c72a626ee83c5f4b47e83 311 Pfam PF03466 LysR substrate binding domain 94 306 2.1E-19 T 11-11-2016 IPR005119 LysR, substrate-binding AUP74_RS12890 3c39dc53451c72a626ee83c5f4b47e83 311 SUPERFAMILY SSF53850 90 306 8.51E-38 T 11-11-2016 AUP74_RS12890 3c39dc53451c72a626ee83c5f4b47e83 311 Gene3D G3DSA:1.10.10.10 1 86 1.4E-30 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS12350 c9349bb37cbfa594846072e18403a6d1 253 SUPERFAMILY SSF54523 41 211 1.41E-30 T 11-11-2016 AUP74_RS12350 c9349bb37cbfa594846072e18403a6d1 253 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 1 25 2.8E-10 T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS12350 c9349bb37cbfa594846072e18403a6d1 253 Pfam PF11612 Type II secretion system (T2SS), protein J 57 207 1.0E-28 T 11-11-2016 IPR010055 Type II secretion system protein J GO:0008565|GO:0015627|GO:0015628 AUP74_RS12350 c9349bb37cbfa594846072e18403a6d1 253 TIGRFAM TIGR01711 gspJ: type II secretion system protein J 6 208 1.5E-29 T 11-11-2016 IPR010055 Type II secretion system protein J GO:0008565|GO:0015627|GO:0015628 AUP74_RS12350 c9349bb37cbfa594846072e18403a6d1 253 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 5 25 - T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS12350 c9349bb37cbfa594846072e18403a6d1 253 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 25 1.2E-9 T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS12350 c9349bb37cbfa594846072e18403a6d1 253 Gene3D G3DSA:2.10.70.20 153 210 1.1E-6 T 11-11-2016 AUP74_RS12350 c9349bb37cbfa594846072e18403a6d1 253 Gene3D G3DSA:3.10.610.10 37 150 2.3E-17 T 11-11-2016 AUP74_RS12765 eaa597e6cfcb3097588696fa4813430c 785 PIRSF PIRSF001227 11 779 2.8E-153 T 11-11-2016 IPR014395 Penicillin acylase GO:0016811 AUP74_RS12765 eaa597e6cfcb3097588696fa4813430c 785 Gene3D G3DSA:1.10.439.10 50 187 4.5E-43 T 11-11-2016 IPR023343 Penicillin amidase type, domain1 GO:0016811 AUP74_RS12765 eaa597e6cfcb3097588696fa4813430c 785 Gene3D G3DSA:3.60.20.10 262 340 1.1E-75 T 11-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal AUP74_RS12765 eaa597e6cfcb3097588696fa4813430c 785 Gene3D G3DSA:3.60.20.10 413 613 1.1E-75 T 11-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal AUP74_RS12765 eaa597e6cfcb3097588696fa4813430c 785 SUPERFAMILY SSF56235 50 777 8.49E-174 T 11-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal AUP74_RS12765 eaa597e6cfcb3097588696fa4813430c 785 Gene3D G3DSA:2.30.120.10 341 404 2.1E-13 T 11-11-2016 AUP74_RS12765 eaa597e6cfcb3097588696fa4813430c 785 Pfam PF01804 Penicillin amidase 52 774 6.2E-143 T 11-11-2016 IPR002692 Penicillin/cephalosporin acylase GO:0016787|GO:0017000 AUP74_RS05960 75677a3e0c1e3bb04b4ca9ea5adb3eff 148 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 2.1E-19 T 11-11-2016 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS05960 75677a3e0c1e3bb04b4ca9ea5adb3eff 148 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 11-11-2016 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS05960 75677a3e0c1e3bb04b4ca9ea5adb3eff 148 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 146 9.9E-26 T 11-11-2016 IPR020069 Ribosomal protein L9, C-terminal AUP74_RS05960 75677a3e0c1e3bb04b4ca9ea5adb3eff 148 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 148 1.5E-47 T 11-11-2016 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS05960 75677a3e0c1e3bb04b4ca9ea5adb3eff 148 Gene3D G3DSA:3.40.5.10 1 52 4.9E-22 T 11-11-2016 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS05960 75677a3e0c1e3bb04b4ca9ea5adb3eff 148 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 25.122 T 11-11-2016 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS05960 75677a3e0c1e3bb04b4ca9ea5adb3eff 148 SUPERFAMILY SSF55658 1 56 1.62E-16 T 11-11-2016 IPR009027 Ribosomal protein L9/RNase H1, N-terminal AUP74_RS05960 75677a3e0c1e3bb04b4ca9ea5adb3eff 148 Gene3D G3DSA:3.10.430.100 62 148 8.6E-28 T 11-11-2016 IPR020069 Ribosomal protein L9, C-terminal AUP74_RS05960 75677a3e0c1e3bb04b4ca9ea5adb3eff 148 SUPERFAMILY SSF55653 61 147 1.83E-24 T 11-11-2016 IPR020069 Ribosomal protein L9, C-terminal AUP74_RS12430 9fbaac302a7dabd85bdd76b3163672c2 130 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 12 99 5.5E-23 T 11-11-2016 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 AUP74_RS12430 9fbaac302a7dabd85bdd76b3163672c2 130 Pfam PF03334 Na+/H+ antiporter subunit 13 91 3.1E-27 T 11-11-2016 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 AUP74_RS10435 92f20ef14596ceecd129fdd4e060f377 260 Pfam PF00226 DnaJ domain 189 254 9.2E-11 T 11-11-2016 IPR001623 DnaJ domain AUP74_RS10435 92f20ef14596ceecd129fdd4e060f377 260 SMART SM00271 187 252 4.4E-10 T 11-11-2016 IPR001623 DnaJ domain AUP74_RS10435 92f20ef14596ceecd129fdd4e060f377 260 PRINTS PR00625 DnaJ domain signature 208 223 7.8E-10 T 11-11-2016 IPR001623 DnaJ domain AUP74_RS10435 92f20ef14596ceecd129fdd4e060f377 260 PRINTS PR00625 DnaJ domain signature 232 252 7.8E-10 T 11-11-2016 IPR001623 DnaJ domain AUP74_RS10435 92f20ef14596ceecd129fdd4e060f377 260 PRINTS PR00625 DnaJ domain signature 190 208 7.8E-10 T 11-11-2016 IPR001623 DnaJ domain AUP74_RS10435 92f20ef14596ceecd129fdd4e060f377 260 Gene3D G3DSA:1.10.287.110 190 254 2.2E-13 T 11-11-2016 IPR001623 DnaJ domain AUP74_RS10435 92f20ef14596ceecd129fdd4e060f377 260 SUPERFAMILY SSF46565 184 254 6.58E-15 T 11-11-2016 IPR001623 DnaJ domain AUP74_RS10435 92f20ef14596ceecd129fdd4e060f377 260 SUPERFAMILY SSF158682 46 202 6.28E-31 T 11-11-2016 IPR029024 TerB-like AUP74_RS10435 92f20ef14596ceecd129fdd4e060f377 260 Gene3D G3DSA:1.10.3680.10 20 189 2.4E-28 T 11-11-2016 IPR029024 TerB-like AUP74_RS10435 92f20ef14596ceecd129fdd4e060f377 260 Pfam PF05099 Tellurite resistance protein TerB 51 170 6.1E-28 T 11-11-2016 IPR007791 Co-chaperone DjlA, N-terminal AUP74_RS00245 c0ea3bb68da59b01c4738c61627039f2 848 Gene3D G3DSA:2.170.130.10 52 165 1.6E-20 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS00245 c0ea3bb68da59b01c4738c61627039f2 848 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 33 848 7.4E-187 T 11-11-2016 IPR010104 Bacterial TonB-dependent receptor AUP74_RS00245 c0ea3bb68da59b01c4738c61627039f2 848 Pfam PF00593 TonB dependent receptor 564 846 2.4E-31 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS00245 c0ea3bb68da59b01c4738c61627039f2 848 SUPERFAMILY SSF56935 24 453 4.58E-96 T 11-11-2016 AUP74_RS00245 c0ea3bb68da59b01c4738c61627039f2 848 SUPERFAMILY SSF56935 496 848 4.58E-96 T 11-11-2016 AUP74_RS00245 c0ea3bb68da59b01c4738c61627039f2 848 Gene3D G3DSA:2.40.170.20 166 278 6.8E-63 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS00245 c0ea3bb68da59b01c4738c61627039f2 848 Gene3D G3DSA:2.40.170.20 511 848 6.8E-63 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS00245 c0ea3bb68da59b01c4738c61627039f2 848 Gene3D G3DSA:2.40.170.20 395 459 6.8E-63 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS00245 c0ea3bb68da59b01c4738c61627039f2 848 Gene3D G3DSA:2.40.170.20 319 357 6.8E-63 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS00245 c0ea3bb68da59b01c4738c61627039f2 848 Pfam PF07715 TonB-dependent Receptor Plug Domain 52 162 3.8E-17 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS15175 7b9b895f5c3343f010bfe0c7b86212c6 426 SUPERFAMILY SSF51556 78 378 7.74E-107 T 11-11-2016 IPR032466 Metal-dependent hydrolase AUP74_RS15175 7b9b895f5c3343f010bfe0c7b86212c6 426 SUPERFAMILY SSF51338 40 87 5.94E-7 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS15175 7b9b895f5c3343f010bfe0c7b86212c6 426 Gene3D G3DSA:3.20.20.140 80 366 1.4E-94 T 11-11-2016 AUP74_RS15175 7b9b895f5c3343f010bfe0c7b86212c6 426 Gene3D G3DSA:2.30.40.10 22 79 3.3E-25 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS15175 7b9b895f5c3343f010bfe0c7b86212c6 426 Gene3D G3DSA:2.30.40.10 393 422 3.3E-25 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS15175 7b9b895f5c3343f010bfe0c7b86212c6 426 SUPERFAMILY SSF51338 353 423 6.98E-24 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS15175 7b9b895f5c3343f010bfe0c7b86212c6 426 Pfam PF01979 Amidohydrolase family 74 418 1.2E-51 T 11-11-2016 IPR006680 Amidohydrolase-related GO:0016787 AUP74_RS15175 7b9b895f5c3343f010bfe0c7b86212c6 426 Gene3D G3DSA:2.30.40.10 367 392 1.7E-6 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS14345 a3be3be2a116a2fbc020eae2c2f11ff3 460 PIRSF PIRSF001109 1 460 1.6E-181 T 11-11-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AUP74_RS14345 a3be3be2a116a2fbc020eae2c2f11ff3 460 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 78 92 - T 11-11-2016 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AUP74_RS14345 a3be3be2a116a2fbc020eae2c2f11ff3 460 SMART SM00997 196 372 4.4E-85 T 11-11-2016 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AUP74_RS14345 a3be3be2a116a2fbc020eae2c2f11ff3 460 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 6 146 1.6E-73 T 11-11-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AUP74_RS14345 a3be3be2a116a2fbc020eae2c2f11ff3 460 Gene3D G3DSA:3.40.50.1480 6 197 8.5E-131 T 11-11-2016 AUP74_RS14345 a3be3be2a116a2fbc020eae2c2f11ff3 460 Gene3D G3DSA:3.40.50.1480 373 460 8.5E-131 T 11-11-2016 AUP74_RS14345 a3be3be2a116a2fbc020eae2c2f11ff3 460 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 218 235 - T 11-11-2016 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AUP74_RS14345 a3be3be2a116a2fbc020eae2c2f11ff3 460 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 7 452 4.0E-157 T 11-11-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AUP74_RS14345 a3be3be2a116a2fbc020eae2c2f11ff3 460 Gene3D G3DSA:3.40.50.720 198 371 8.4E-44 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS14345 a3be3be2a116a2fbc020eae2c2f11ff3 460 SMART SM00996 6 459 3.2E-278 T 11-11-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AUP74_RS14345 a3be3be2a116a2fbc020eae2c2f11ff3 460 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 2 452 44.33 T 11-11-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AUP74_RS14345 a3be3be2a116a2fbc020eae2c2f11ff3 460 SUPERFAMILY SSF52283 373 460 3.06E-109 T 11-11-2016 AUP74_RS14345 a3be3be2a116a2fbc020eae2c2f11ff3 460 SUPERFAMILY SSF52283 4 195 3.06E-109 T 11-11-2016 AUP74_RS14345 a3be3be2a116a2fbc020eae2c2f11ff3 460 SUPERFAMILY SSF51735 196 373 4.13E-52 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS14345 a3be3be2a116a2fbc020eae2c2f11ff3 460 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 196 372 4.7E-58 T 11-11-2016 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AUP74_RS01420 8c2aca4c74541da8dd0673d1b3b20b53 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 80 3.0E-8 T 11-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AUP74_RS01420 8c2aca4c74541da8dd0673d1b3b20b53 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 100 3.0E-8 T 11-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AUP74_RS01420 8c2aca4c74541da8dd0673d1b3b20b53 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 48 64 3.0E-8 T 11-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AUP74_RS01420 8c2aca4c74541da8dd0673d1b3b20b53 169 SUPERFAMILY SSF46785 4 140 2.39E-32 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS01420 8c2aca4c74541da8dd0673d1b3b20b53 169 Gene3D G3DSA:1.10.10.10 2 139 2.1E-38 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS01420 8c2aca4c74541da8dd0673d1b3b20b53 169 Pfam PF01047 MarR family 31 89 3.3E-19 T 11-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AUP74_RS01420 8c2aca4c74541da8dd0673d1b3b20b53 169 SMART SM00347 24 124 3.8E-24 T 11-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AUP74_RS01415 6d9e2a9dca0b077f9b9f0eeafa41a980 162 TIGRFAM TIGR02406 ectoine_EctA: diaminobutyrate acetyltransferase 2 156 2.1E-62 T 11-11-2016 IPR012772 L-2,4-diaminobutyric acid acetyltransferase GO:0019491|GO:0033816 KEGG: 00250+2.3.1.17|KEGG: 00260+2.3.1.178 AUP74_RS01415 6d9e2a9dca0b077f9b9f0eeafa41a980 162 Gene3D G3DSA:3.40.630.30 2 158 7.8E-71 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS01415 6d9e2a9dca0b077f9b9f0eeafa41a980 162 Pfam PF00583 Acetyltransferase (GNAT) family 45 119 2.1E-9 T 11-11-2016 IPR000182 GNAT domain GO:0008080 AUP74_RS01415 6d9e2a9dca0b077f9b9f0eeafa41a980 162 SUPERFAMILY SSF55729 2 121 1.92E-16 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS06480 e2e1ed80f547d40f437bd9a93d1c0e6e 214 SUPERFAMILY SSF47240 49 128 5.66E-18 T 11-11-2016 IPR009078 Ferritin-like superfamily AUP74_RS06480 e2e1ed80f547d40f437bd9a93d1c0e6e 214 Hamap MF_01658 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase [coq7]. 13 214 31.997 T 11-11-2016 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 AUP74_RS06480 e2e1ed80f547d40f437bd9a93d1c0e6e 214 Gene3D G3DSA:1.20.1260.10 51 181 1.6E-9 T 11-11-2016 IPR012347 Ferritin-related AUP74_RS06480 e2e1ed80f547d40f437bd9a93d1c0e6e 214 Pfam PF03232 Ubiquinone biosynthesis protein COQ7 54 212 2.6E-41 T 11-11-2016 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 AUP74_RS03565 75d1508d18787ac5ed5c39b7622a6cc9 470 Pfam PF02954 Bacterial regulatory protein, Fis family 423 463 3.7E-14 T 11-11-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AUP74_RS03565 75d1508d18787ac5ed5c39b7622a6cc9 470 SMART SM00382 161 304 2.3E-11 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS03565 75d1508d18787ac5ed5c39b7622a6cc9 470 Gene3D G3DSA:1.10.8.60 314 388 6.4E-22 T 11-11-2016 AUP74_RS03565 75d1508d18787ac5ed5c39b7622a6cc9 470 Gene3D G3DSA:3.40.50.2300 3 132 9.6E-35 T 11-11-2016 AUP74_RS03565 75d1508d18787ac5ed5c39b7622a6cc9 470 SUPERFAMILY SSF52172 4 186 8.25E-42 T 11-11-2016 IPR011006 CheY-like superfamily AUP74_RS03565 75d1508d18787ac5ed5c39b7622a6cc9 470 TIGRFAM TIGR01818 ntrC: nitrogen regulation protein NR(I) 5 463 7.8E-230 T 11-11-2016 IPR010114 Signal transduction response regulator, nitrogen regulation NR(I) GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0006808 AUP74_RS03565 75d1508d18787ac5ed5c39b7622a6cc9 470 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 446 466 8.8E-9 T 11-11-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AUP74_RS03565 75d1508d18787ac5ed5c39b7622a6cc9 470 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 429 446 8.8E-9 T 11-11-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AUP74_RS03565 75d1508d18787ac5ed5c39b7622a6cc9 470 SUPERFAMILY SSF46689 381 465 3.27E-20 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS03565 75d1508d18787ac5ed5c39b7622a6cc9 470 Gene3D G3DSA:1.10.10.60 396 466 1.8E-21 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS03565 75d1508d18787ac5ed5c39b7622a6cc9 470 SUPERFAMILY SSF52540 140 384 3.52E-73 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03565 75d1508d18787ac5ed5c39b7622a6cc9 470 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 227 242 - T 11-11-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 AUP74_RS03565 75d1508d18787ac5ed5c39b7622a6cc9 470 Pfam PF00158 Sigma-54 interaction domain 141 308 6.9E-72 T 11-11-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 AUP74_RS03565 75d1508d18787ac5ed5c39b7622a6cc9 470 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 354 363 - T 11-11-2016 IPR025944 Sigma-54 interaction domain, conserved site AUP74_RS03565 75d1508d18787ac5ed5c39b7622a6cc9 470 Gene3D G3DSA:3.40.50.300 139 312 9.4E-61 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03565 75d1508d18787ac5ed5c39b7622a6cc9 470 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 165 178 - T 11-11-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 AUP74_RS03565 75d1508d18787ac5ed5c39b7622a6cc9 470 SMART SM00448 3 114 7.4E-32 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS03565 75d1508d18787ac5ed5c39b7622a6cc9 470 Pfam PF00072 Response regulator receiver domain 5 112 3.1E-26 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS09080 bcfc2ca38e0c84c7254fb9df41e13372 381 PRINTS PR00075 Fatty acid desaturase family 1 signature 61 81 7.7E-34 T 11-11-2016 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 AUP74_RS09080 bcfc2ca38e0c84c7254fb9df41e13372 381 PRINTS PR00075 Fatty acid desaturase family 1 signature 11 31 7.7E-34 T 11-11-2016 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 AUP74_RS09080 bcfc2ca38e0c84c7254fb9df41e13372 381 PRINTS PR00075 Fatty acid desaturase family 1 signature 157 175 7.7E-34 T 11-11-2016 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 AUP74_RS09080 bcfc2ca38e0c84c7254fb9df41e13372 381 PRINTS PR00075 Fatty acid desaturase family 1 signature 188 209 7.7E-34 T 11-11-2016 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 AUP74_RS09080 bcfc2ca38e0c84c7254fb9df41e13372 381 PRINTS PR00075 Fatty acid desaturase family 1 signature 99 128 7.7E-34 T 11-11-2016 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 AUP74_RS09080 bcfc2ca38e0c84c7254fb9df41e13372 381 PRINTS PR00075 Fatty acid desaturase family 1 signature 231 245 7.7E-34 T 11-11-2016 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 AUP74_RS09080 bcfc2ca38e0c84c7254fb9df41e13372 381 Pfam PF00487 Fatty acid desaturase 39 262 2.5E-22 T 11-11-2016 IPR005804 Fatty acid desaturase domain GO:0006629 AUP74_RS02445 d07bec29363f0421a8c95b69bca8e966 442 Gene3D G3DSA:3.90.230.10 177 434 3.6E-83 T 11-11-2016 IPR000994 Peptidase M24, structural domain AUP74_RS02445 d07bec29363f0421a8c95b69bca8e966 442 SUPERFAMILY SSF55920 174 432 5.76E-83 T 11-11-2016 IPR000994 Peptidase M24, structural domain AUP74_RS02445 d07bec29363f0421a8c95b69bca8e966 442 Pfam PF00557 Metallopeptidase family M24 180 409 2.4E-61 T 11-11-2016 IPR000994 Peptidase M24, structural domain AUP74_RS02445 d07bec29363f0421a8c95b69bca8e966 442 Pfam PF05195 Aminopeptidase P, N-terminal domain 8 127 7.4E-38 T 11-11-2016 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 AUP74_RS02445 d07bec29363f0421a8c95b69bca8e966 442 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 347 359 - T 11-11-2016 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site AUP74_RS02445 d07bec29363f0421a8c95b69bca8e966 442 SMART SM01011 3 137 7.2E-60 T 11-11-2016 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 AUP74_RS02445 d07bec29363f0421a8c95b69bca8e966 442 SUPERFAMILY SSF53092 3 173 6.28E-47 T 11-11-2016 IPR028980 Creatinase/Aminopeptidase P, N-terminal AUP74_RS02445 d07bec29363f0421a8c95b69bca8e966 442 PRINTS PR00599 Methionine aminopeptidase-1 signature 252 268 3.0E-5 T 11-11-2016 IPR001714 Peptidase M24, methionine aminopeptidase AUP74_RS02445 d07bec29363f0421a8c95b69bca8e966 442 PRINTS PR00599 Methionine aminopeptidase-1 signature 370 382 3.0E-5 T 11-11-2016 IPR001714 Peptidase M24, methionine aminopeptidase AUP74_RS02445 d07bec29363f0421a8c95b69bca8e966 442 Gene3D G3DSA:3.40.350.10 3 176 2.7E-53 T 11-11-2016 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal AUP74_RS15715 ce9ab71b9c5dc38c83d8f3b38b80198e 235 SUPERFAMILY SSF46894 135 230 2.55E-22 T 11-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AUP74_RS15715 ce9ab71b9c5dc38c83d8f3b38b80198e 235 Gene3D G3DSA:1.10.10.10 133 231 2.2E-24 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS15715 ce9ab71b9c5dc38c83d8f3b38b80198e 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 229 6.3E-20 T 11-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AUP74_RS15715 ce9ab71b9c5dc38c83d8f3b38b80198e 235 SMART SM00448 2 116 1.3E-40 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS15715 ce9ab71b9c5dc38c83d8f3b38b80198e 235 SMART SM00862 153 229 1.4E-19 T 11-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AUP74_RS15715 ce9ab71b9c5dc38c83d8f3b38b80198e 235 Gene3D G3DSA:3.40.50.2300 1 128 3.7E-39 T 11-11-2016 AUP74_RS15715 ce9ab71b9c5dc38c83d8f3b38b80198e 235 SUPERFAMILY SSF52172 2 127 2.13E-39 T 11-11-2016 IPR011006 CheY-like superfamily AUP74_RS15715 ce9ab71b9c5dc38c83d8f3b38b80198e 235 Pfam PF00072 Response regulator receiver domain 4 116 3.4E-26 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS13245 076f7ae215d2e7538e6d577cb366bfee 332 Pfam PF03537 Glycoside-hydrolase family GH114 213 327 8.8E-11 T 11-11-2016 IPR004352 Glycoside-hydrolase family GH114, TIM-barrel domain AUP74_RS13245 076f7ae215d2e7538e6d577cb366bfee 332 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 286 304 1.0E-10 T 11-11-2016 IPR016062 Hypothetical protein TM1410-related AUP74_RS13245 076f7ae215d2e7538e6d577cb366bfee 332 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 211 224 1.0E-10 T 11-11-2016 IPR016062 Hypothetical protein TM1410-related AUP74_RS13245 076f7ae215d2e7538e6d577cb366bfee 332 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 244 263 1.0E-10 T 11-11-2016 IPR016062 Hypothetical protein TM1410-related AUP74_RS13245 076f7ae215d2e7538e6d577cb366bfee 332 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 267 284 1.0E-10 T 11-11-2016 IPR016062 Hypothetical protein TM1410-related AUP74_RS13245 076f7ae215d2e7538e6d577cb366bfee 332 SUPERFAMILY SSF51445 206 328 4.42E-14 T 11-11-2016 IPR017853 Glycoside hydrolase superfamily AUP74_RS02580 3695a8451555c2bb65d3bef8ffbb11c5 229 SUPERFAMILY SSF47616 81 228 4.04E-38 T 11-11-2016 IPR010987 Glutathione S-transferase, C-terminal-like AUP74_RS02580 3695a8451555c2bb65d3bef8ffbb11c5 229 Pfam PF14497 Glutathione S-transferase, C-terminal domain 118 204 6.4E-13 T 11-11-2016 IPR004046 Glutathione S-transferase, C-terminal AUP74_RS02580 3695a8451555c2bb65d3bef8ffbb11c5 229 Gene3D G3DSA:1.20.1050.10 112 208 9.1E-12 T 11-11-2016 IPR010987 Glutathione S-transferase, C-terminal-like AUP74_RS02580 3695a8451555c2bb65d3bef8ffbb11c5 229 Gene3D G3DSA:3.40.30.10 1 106 9.5E-19 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS02580 3695a8451555c2bb65d3bef8ffbb11c5 229 SUPERFAMILY SSF52833 2 79 5.36E-12 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS14455 ec791d4364dcb7841f4d95ccda4625b6 271 Pfam PF06405 Red chlorophyll catabolite reductase (RCC reductase) 54 262 1.2E-10 T 11-11-2016 IPR009439 Red chlorophyll catabolite reductase AUP74_RS10970 24ca72f5666d3422c5e1f1ba43b4e635 679 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 413 440 2.0E-10 T 11-11-2016 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 AUP74_RS10970 24ca72f5666d3422c5e1f1ba43b4e635 679 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 10 324 3.6E-134 T 11-11-2016 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 AUP74_RS10970 24ca72f5666d3422c5e1f1ba43b4e635 679 Gene3D G3DSA:3.30.470.30 125 258 4.4E-52 T 11-11-2016 AUP74_RS10970 24ca72f5666d3422c5e1f1ba43b4e635 679 Gene3D G3DSA:3.40.50.10190 597 675 1.2E-23 T 11-11-2016 IPR001357 BRCT domain AUP74_RS10970 24ca72f5666d3422c5e1f1ba43b4e635 679 Pfam PF14520 Helix-hairpin-helix domain 452 507 2.2E-5 T 11-11-2016 AUP74_RS10970 24ca72f5666d3422c5e1f1ba43b4e635 679 SUPERFAMILY SSF47781 409 590 5.56E-62 T 11-11-2016 IPR010994 RuvA domain 2-like AUP74_RS10970 24ca72f5666d3422c5e1f1ba43b4e635 679 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 337 352 - T 11-11-2016 IPR033136 NAD-dependent DNA ligase, conserved site AUP74_RS10970 24ca72f5666d3422c5e1f1ba43b4e635 679 SMART SM00532 9 454 3.8E-273 T 11-11-2016 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 AUP74_RS10970 24ca72f5666d3422c5e1f1ba43b4e635 679 Gene3D G3DSA:2.40.50.140 325 397 4.7E-35 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS10970 24ca72f5666d3422c5e1f1ba43b4e635 679 SMART SM00278 518 537 180.0 T 11-11-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AUP74_RS10970 24ca72f5666d3422c5e1f1ba43b4e635 679 SMART SM00278 452 471 63.0 T 11-11-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AUP74_RS10970 24ca72f5666d3422c5e1f1ba43b4e635 679 SMART SM00278 550 569 330.0 T 11-11-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AUP74_RS10970 24ca72f5666d3422c5e1f1ba43b4e635 679 SMART SM00278 486 505 0.42 T 11-11-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AUP74_RS10970 24ca72f5666d3422c5e1f1ba43b4e635 679 Gene3D G3DSA:1.10.150.20 510 589 5.8E-31 T 11-11-2016 AUP74_RS10970 24ca72f5666d3422c5e1f1ba43b4e635 679 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 328 404 1.5E-35 T 11-11-2016 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 AUP74_RS10970 24ca72f5666d3422c5e1f1ba43b4e635 679 Gene3D G3DSA:1.10.150.20 441 509 1.5E-28 T 11-11-2016 AUP74_RS10970 24ca72f5666d3422c5e1f1ba43b4e635 679 SMART SM00292 598 675 5.3E-8 T 11-11-2016 IPR001357 BRCT domain AUP74_RS10970 24ca72f5666d3422c5e1f1ba43b4e635 679 SUPERFAMILY SSF52113 597 674 4.67E-17 T 11-11-2016 IPR001357 BRCT domain AUP74_RS10970 24ca72f5666d3422c5e1f1ba43b4e635 679 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 121 150 - T 11-11-2016 IPR018239 NAD-dependent DNA ligase, active site AUP74_RS10970 24ca72f5666d3422c5e1f1ba43b4e635 679 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 600 671 9.9E-8 T 11-11-2016 IPR001357 BRCT domain AUP74_RS10970 24ca72f5666d3422c5e1f1ba43b4e635 679 Hamap MF_01588 DNA ligase [ligA]. 8 672 54.39 T 11-11-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 AUP74_RS10970 24ca72f5666d3422c5e1f1ba43b4e635 679 SUPERFAMILY SSF56091 9 322 5.16E-123 T 11-11-2016 AUP74_RS10970 24ca72f5666d3422c5e1f1ba43b4e635 679 PIRSF PIRSF001604 1 677 7.4E-251 T 11-11-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 AUP74_RS10970 24ca72f5666d3422c5e1f1ba43b4e635 679 Pfam PF12826 Helix-hairpin-helix motif 516 578 1.7E-22 T 11-11-2016 AUP74_RS10970 24ca72f5666d3422c5e1f1ba43b4e635 679 SUPERFAMILY SSF50249 324 405 1.08E-28 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS10970 24ca72f5666d3422c5e1f1ba43b4e635 679 Gene3D G3DSA:1.10.287.610 8 73 5.2E-27 T 11-11-2016 AUP74_RS10970 24ca72f5666d3422c5e1f1ba43b4e635 679 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 18 668 1.1E-259 T 11-11-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 AUP74_RS06230 3ee73d6d6f6b5165536bff46b1b77ad8 467 SUPERFAMILY SSF144091 131 288 6.93E-31 T 11-11-2016 AUP74_RS06230 3ee73d6d6f6b5165536bff46b1b77ad8 467 SUPERFAMILY SSF144091 12 52 6.93E-31 T 11-11-2016 AUP74_RS06230 3ee73d6d6f6b5165536bff46b1b77ad8 467 Gene3D G3DSA:1.20.1540.10 121 285 5.0E-32 T 11-11-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 AUP74_RS06230 3ee73d6d6f6b5165536bff46b1b77ad8 467 Gene3D G3DSA:1.20.1540.10 15 38 5.0E-32 T 11-11-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 AUP74_RS06230 3ee73d6d6f6b5165536bff46b1b77ad8 467 Pfam PF01694 Rhomboid family 139 287 2.7E-28 T 11-11-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 AUP74_RS10905 77eecc6ee41bb9ceba644aa5dad048f9 194 TIGRFAM TIGR00385 dsbE: periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily 6 172 1.3E-54 T 11-11-2016 IPR004799 Periplasmic protein thiol:disulphide oxidoreductase DsbE GO:0015036|GO:0017004|GO:0030288 AUP74_RS10905 77eecc6ee41bb9ceba644aa5dad048f9 194 Pfam PF08534 Redoxin 37 158 1.1E-21 T 11-11-2016 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 AUP74_RS10905 77eecc6ee41bb9ceba644aa5dad048f9 194 Gene3D G3DSA:3.40.30.10 7 174 1.2E-40 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS10905 77eecc6ee41bb9ceba644aa5dad048f9 194 SUPERFAMILY SSF52833 41 174 1.19E-35 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS08385 1ed58a13304911aabb146c5e1c68328a 500 SUPERFAMILY SSF51905 2 82 1.01E-23 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS08385 1ed58a13304911aabb146c5e1c68328a 500 SUPERFAMILY SSF51905 315 419 1.01E-23 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS08385 1ed58a13304911aabb146c5e1c68328a 500 SUPERFAMILY SSF51905 132 228 1.01E-23 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS08385 1ed58a13304911aabb146c5e1c68328a 500 PIRSF PIRSF011396 1 499 7.1E-138 T 11-11-2016 IPR006905 Tryptophan halogenase AUP74_RS08385 1ed58a13304911aabb146c5e1c68328a 500 Pfam PF04820 Tryptophan halogenase 1 464 1.3E-115 T 11-11-2016 IPR006905 Tryptophan halogenase AUP74_RS08385 1ed58a13304911aabb146c5e1c68328a 500 Gene3D G3DSA:3.50.50.60 148 226 7.3E-41 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS08385 1ed58a13304911aabb146c5e1c68328a 500 Gene3D G3DSA:3.50.50.60 310 353 7.3E-41 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS08385 1ed58a13304911aabb146c5e1c68328a 500 Gene3D G3DSA:3.50.50.60 2 67 7.3E-41 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS06070 98db98df79f04616c84c4fac837419fd 695 SUPERFAMILY SSF52172 5 122 1.99E-8 T 11-11-2016 IPR011006 CheY-like superfamily AUP74_RS06070 98db98df79f04616c84c4fac837419fd 695 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 272 423 4.8E-24 T 11-11-2016 IPR000160 GGDEF domain AUP74_RS06070 98db98df79f04616c84c4fac837419fd 695 Pfam PF00990 Diguanylate cyclase, GGDEF domain 272 425 1.4E-26 T 11-11-2016 IPR000160 GGDEF domain AUP74_RS06070 98db98df79f04616c84c4fac837419fd 695 Gene3D G3DSA:3.30.450.20 141 246 1.5E-10 T 11-11-2016 AUP74_RS06070 98db98df79f04616c84c4fac837419fd 695 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 144 237 5.9E-7 T 11-11-2016 IPR000014 PAS domain AUP74_RS06070 98db98df79f04616c84c4fac837419fd 695 Pfam PF00563 EAL domain 451 684 1.3E-44 T 11-11-2016 IPR001633 EAL domain AUP74_RS06070 98db98df79f04616c84c4fac837419fd 695 SMART SM00052 445 689 1.1E-25 T 11-11-2016 IPR001633 EAL domain AUP74_RS06070 98db98df79f04616c84c4fac837419fd 695 Pfam PF00989 PAS fold 147 236 2.2E-8 T 11-11-2016 IPR013767 PAS fold GO:0006355 AUP74_RS06070 98db98df79f04616c84c4fac837419fd 695 SUPERFAMILY SSF55785 137 247 2.27E-8 T 11-11-2016 IPR000014 PAS domain AUP74_RS06070 98db98df79f04616c84c4fac837419fd 695 Gene3D G3DSA:3.40.50.2300 6 114 3.6E-9 T 11-11-2016 AUP74_RS06070 98db98df79f04616c84c4fac837419fd 695 SMART SM00267 260 435 4.1E-31 T 11-11-2016 IPR000160 GGDEF domain AUP74_RS06070 98db98df79f04616c84c4fac837419fd 695 SUPERFAMILY SSF55073 276 427 2.67E-26 T 11-11-2016 IPR029787 Nucleotide cyclase AUP74_RS06070 98db98df79f04616c84c4fac837419fd 695 SUPERFAMILY SSF141868 452 686 1.05E-42 T 11-11-2016 IPR001633 EAL domain AUP74_RS06070 98db98df79f04616c84c4fac837419fd 695 Gene3D G3DSA:3.30.70.270 273 440 9.8E-33 T 11-11-2016 AUP74_RS06070 98db98df79f04616c84c4fac837419fd 695 SMART SM00091 144 210 0.0014 T 11-11-2016 IPR000014 PAS domain AUP74_RS06070 98db98df79f04616c84c4fac837419fd 695 Gene3D G3DSA:3.20.20.450 452 687 2.7E-45 T 11-11-2016 IPR001633 EAL domain AUP74_RS00565 c3d70d0a25cee16524acba291a280671 285 Hamap MF_00697 UPF0276 protein . 14 280 44.976 T 11-11-2016 IPR007801 Uncharacterised protein family UPF0276 AUP74_RS00565 c3d70d0a25cee16524acba291a280671 285 SUPERFAMILY SSF51658 33 223 6.47E-13 T 11-11-2016 IPR013022 Xylose isomerase-like, TIM barrel domain AUP74_RS00565 c3d70d0a25cee16524acba291a280671 285 Gene3D G3DSA:3.20.20.150 12 275 4.2E-100 T 11-11-2016 IPR013022 Xylose isomerase-like, TIM barrel domain AUP74_RS00565 c3d70d0a25cee16524acba291a280671 285 Pfam PF05114 Protein of unknown function (DUF692) 13 272 2.0E-104 T 11-11-2016 IPR007801 Uncharacterised protein family UPF0276 AUP74_RS11085 709168af22fe1cce32dfe4500c78856f 555 Gene3D G3DSA:3.90.1010.10 428 546 7.7E-34 T 11-11-2016 AUP74_RS11085 709168af22fe1cce32dfe4500c78856f 555 SUPERFAMILY SSF53383 8 401 1.88E-107 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase AUP74_RS11085 709168af22fe1cce32dfe4500c78856f 555 Gene3D G3DSA:3.90.1150.10 285 400 1.6E-20 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS11085 709168af22fe1cce32dfe4500c78856f 555 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 217 236 - T 11-11-2016 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site AUP74_RS11085 709168af22fe1cce32dfe4500c78856f 555 Gene3D G3DSA:3.40.640.10 38 284 1.2E-74 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AUP74_RS11085 709168af22fe1cce32dfe4500c78856f 555 Pfam PF02657 Fe-S metabolism associated domain 429 544 4.9E-30 T 11-11-2016 IPR003808 Fe-S metabolism associated domain, SufE-like AUP74_RS11085 709168af22fe1cce32dfe4500c78856f 555 Pfam PF00266 Aminotransferase class-V 27 394 1.6E-119 T 11-11-2016 IPR000192 Aminotransferase class V domain AUP74_RS11085 709168af22fe1cce32dfe4500c78856f 555 SUPERFAMILY SSF82649 428 544 8.89E-30 T 11-11-2016 AUP74_RS10750 993d929576cef8b32f5243fd7231f6a5 418 Pfam PF06738 Putative threonine/serine exporter 36 255 1.7E-31 T 11-11-2016 IPR010619 Putative threonine/serine exporter AUP74_RS13895 63647838d68ea4ae706c221a51b107a4 105 SUPERFAMILY SSF47413 20 60 2.62E-10 T 11-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AUP74_RS13895 63647838d68ea4ae706c221a51b107a4 105 SMART SM00530 26 76 6.4E-6 T 11-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AUP74_RS13895 63647838d68ea4ae706c221a51b107a4 105 Pfam PF13560 Helix-turn-helix domain 23 75 5.5E-9 T 11-11-2016 AUP74_RS13895 63647838d68ea4ae706c221a51b107a4 105 Gene3D G3DSA:1.10.260.40 22 60 1.1E-9 T 11-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AUP74_RS00205 1f6cb6c1f449a8bf64bb24e3c14ca612 363 Pfam PF06071 Protein of unknown function (DUF933) 279 362 2.4E-39 T 11-11-2016 IPR013029 Domain of unknown function DUF933 AUP74_RS00205 1f6cb6c1f449a8bf64bb24e3c14ca612 363 PIRSF PIRSF006641 1 363 7.5E-157 T 11-11-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 AUP74_RS00205 1f6cb6c1f449a8bf64bb24e3c14ca612 363 Gene3D G3DSA:3.10.20.30 267 363 7.6E-50 T 11-11-2016 IPR012675 Beta-grasp domain AUP74_RS00205 1f6cb6c1f449a8bf64bb24e3c14ca612 363 Gene3D G3DSA:3.40.50.300 201 266 5.6E-44 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS00205 1f6cb6c1f449a8bf64bb24e3c14ca612 363 Gene3D G3DSA:3.40.50.300 4 131 5.6E-44 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS00205 1f6cb6c1f449a8bf64bb24e3c14ca612 363 Gene3D G3DSA:1.10.150.300 132 200 1.5E-25 T 11-11-2016 IPR023192 TGS-like domain AUP74_RS00205 1f6cb6c1f449a8bf64bb24e3c14ca612 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 5.2E-33 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 AUP74_RS00205 1f6cb6c1f449a8bf64bb24e3c14ca612 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 5.2E-33 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 AUP74_RS00205 1f6cb6c1f449a8bf64bb24e3c14ca612 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 5.2E-33 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 AUP74_RS00205 1f6cb6c1f449a8bf64bb24e3c14ca612 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 5.2E-33 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 AUP74_RS00205 1f6cb6c1f449a8bf64bb24e3c14ca612 363 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 363 45.413 T 11-11-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 AUP74_RS00205 1f6cb6c1f449a8bf64bb24e3c14ca612 363 SUPERFAMILY SSF52540 3 301 1.12E-82 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS00205 1f6cb6c1f449a8bf64bb24e3c14ca612 363 Pfam PF01926 50S ribosome-binding GTPase 5 120 3.3E-21 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 AUP74_RS00205 1f6cb6c1f449a8bf64bb24e3c14ca612 363 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 363 6.7E-161 T 11-11-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 AUP74_RS00205 1f6cb6c1f449a8bf64bb24e3c14ca612 363 SUPERFAMILY SSF81271 279 360 5.89E-36 T 11-11-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 AUP74_RS10620 4c7c9b3e4f083a2919adc422b354426d 257 Pfam PF01061 ABC-2 type transporter 9 218 1.0E-39 T 11-11-2016 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AUP74_RS10620 4c7c9b3e4f083a2919adc422b354426d 257 PIRSF PIRSF006648 4 254 1.2E-24 T 11-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 AUP74_RS10620 4c7c9b3e4f083a2919adc422b354426d 257 PRINTS PR00164 ABC-2 type transport system membrane protein signature 177 196 7.8E-6 T 11-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 AUP74_RS10620 4c7c9b3e4f083a2919adc422b354426d 257 PRINTS PR00164 ABC-2 type transport system membrane protein signature 139 163 7.8E-6 T 11-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 AUP74_RS10620 4c7c9b3e4f083a2919adc422b354426d 257 PRINTS PR00164 ABC-2 type transport system membrane protein signature 59 81 7.8E-6 T 11-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 AUP74_RS10620 4c7c9b3e4f083a2919adc422b354426d 257 PRINTS PR00164 ABC-2 type transport system membrane protein signature 197 216 7.8E-6 T 11-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 AUP74_RS14470 5c81e0d7ea23e8e0959ac552c1e3fcd0 153 Pfam PF09912 Uncharacterized protein conserved in bacteria (DUF2141) 38 142 4.3E-28 T 11-11-2016 IPR018673 Protein of unknown function DUF2141 AUP74_RS06085 bffb8427a9c8f1373792349ea21b00fc 1037 Gene3D G3DSA:1.10.3850.10 800 1015 7.1E-56 T 11-11-2016 AUP74_RS06085 bffb8427a9c8f1373792349ea21b00fc 1037 SUPERFAMILY SSF82693 555 659 1.46E-16 T 11-11-2016 AUP74_RS06085 bffb8427a9c8f1373792349ea21b00fc 1037 SUPERFAMILY SSF82714 182 265 1.07E-18 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS06085 bffb8427a9c8f1373792349ea21b00fc 1037 SUPERFAMILY SSF82866 793 1015 4.05E-46 T 11-11-2016 AUP74_RS06085 bffb8427a9c8f1373792349ea21b00fc 1037 Gene3D G3DSA:1.20.1640.10 285 496 7.5E-58 T 11-11-2016 AUP74_RS06085 bffb8427a9c8f1373792349ea21b00fc 1037 Gene3D G3DSA:3.30.2090.10 181 266 1.8E-23 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS06085 bffb8427a9c8f1373792349ea21b00fc 1037 Gene3D G3DSA:3.30.2090.10 706 793 1.3E-20 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS06085 bffb8427a9c8f1373792349ea21b00fc 1037 Gene3D G3DSA:3.30.70.1430 557 653 7.1E-10 T 11-11-2016 AUP74_RS06085 bffb8427a9c8f1373792349ea21b00fc 1037 SUPERFAMILY SSF82714 707 792 4.32E-18 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS06085 bffb8427a9c8f1373792349ea21b00fc 1037 Gene3D G3DSA:3.30.70.1430 40 141 7.8E-30 T 11-11-2016 AUP74_RS06085 bffb8427a9c8f1373792349ea21b00fc 1037 SUPERFAMILY SSF82693 136 181 5.41E-22 T 11-11-2016 AUP74_RS06085 bffb8427a9c8f1373792349ea21b00fc 1037 SUPERFAMILY SSF82693 268 324 5.41E-22 T 11-11-2016 AUP74_RS06085 bffb8427a9c8f1373792349ea21b00fc 1037 Pfam PF00873 AcrB/AcrD/AcrF family 3 1012 1.6E-297 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS06085 bffb8427a9c8f1373792349ea21b00fc 1037 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 1.1E-78 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS06085 bffb8427a9c8f1373792349ea21b00fc 1037 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.1E-78 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS06085 bffb8427a9c8f1373792349ea21b00fc 1037 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 1.1E-78 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS06085 bffb8427a9c8f1373792349ea21b00fc 1037 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.1E-78 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS06085 bffb8427a9c8f1373792349ea21b00fc 1037 PRINTS PR00702 Acriflavin resistance protein family signature 613 627 1.1E-78 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS06085 bffb8427a9c8f1373792349ea21b00fc 1037 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 1.1E-78 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS06085 bffb8427a9c8f1373792349ea21b00fc 1037 PRINTS PR00702 Acriflavin resistance protein family signature 439 462 1.1E-78 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS06085 bffb8427a9c8f1373792349ea21b00fc 1037 PRINTS PR00702 Acriflavin resistance protein family signature 542 559 1.1E-78 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS06085 bffb8427a9c8f1373792349ea21b00fc 1037 PRINTS PR00702 Acriflavin resistance protein family signature 464 487 1.1E-78 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS06085 bffb8427a9c8f1373792349ea21b00fc 1037 SUPERFAMILY SSF82693 40 134 2.17E-25 T 11-11-2016 AUP74_RS06085 bffb8427a9c8f1373792349ea21b00fc 1037 SUPERFAMILY SSF82866 295 490 1.12E-48 T 11-11-2016 AUP74_RS15420 143351d980e331fda19441c83e20a19e 204 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 185 6.1E-31 T 11-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS15420 143351d980e331fda19441c83e20a19e 204 Pfam PF04542 Sigma-70 region 2 28 95 6.0E-17 T 11-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS15420 143351d980e331fda19441c83e20a19e 204 Pfam PF08281 Sigma-70, region 4 134 184 9.1E-20 T 11-11-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS15420 143351d980e331fda19441c83e20a19e 204 SUPERFAMILY SSF88659 125 186 2.24E-18 T 11-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS15420 143351d980e331fda19441c83e20a19e 204 Gene3D G3DSA:1.10.10.10 126 187 5.7E-26 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS15420 143351d980e331fda19441c83e20a19e 204 TIGRFAM TIGR02939 RpoE_Sigma70: RNA polymerase sigma factor RpoE 6 192 6.2E-97 T 11-11-2016 IPR014286 RNA polymerase sigma-70 RpoE type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS15420 143351d980e331fda19441c83e20a19e 204 Gene3D G3DSA:1.10.1740.10 6 113 1.2E-36 T 11-11-2016 AUP74_RS15420 143351d980e331fda19441c83e20a19e 204 SUPERFAMILY SSF88946 7 109 3.61E-31 T 11-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS05820 3661e00c5291bf53ec49fa8b95cdd86e 634 Gene3D G3DSA:3.30.230.10 220 331 3.5E-38 T 11-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AUP74_RS05820 3661e00c5291bf53ec49fa8b95cdd86e 634 SUPERFAMILY SSF55874 3 210 9.56E-52 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS05820 3661e00c5291bf53ec49fa8b95cdd86e 634 SMART SM00853 447 590 3.5E-54 T 11-11-2016 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 AUP74_RS05820 3661e00c5291bf53ec49fa8b95cdd86e 634 Pfam PF08676 MutL C terminal dimerisation domain 443 590 1.1E-50 T 11-11-2016 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 AUP74_RS05820 3661e00c5291bf53ec49fa8b95cdd86e 634 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 95 101 - T 11-11-2016 IPR014762 DNA mismatch repair, conserved site AUP74_RS05820 3661e00c5291bf53ec49fa8b95cdd86e 634 SMART SM01340 214 332 1.9E-59 T 11-11-2016 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 AUP74_RS05820 3661e00c5291bf53ec49fa8b95cdd86e 634 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 3 630 28.934 T 11-11-2016 IPR020667 DNA mismatch repair protein, MutL GO:0006298 AUP74_RS05820 3661e00c5291bf53ec49fa8b95cdd86e 634 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 4 312 1.7E-101 T 11-11-2016 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 AUP74_RS05820 3661e00c5291bf53ec49fa8b95cdd86e 634 Gene3D G3DSA:3.30.565.10 4 219 1.8E-72 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS05820 3661e00c5291bf53ec49fa8b95cdd86e 634 SUPERFAMILY SSF54211 193 332 1.06E-38 T 11-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold AUP74_RS05820 3661e00c5291bf53ec49fa8b95cdd86e 634 SUPERFAMILY SSF118116 443 632 6.67E-62 T 11-11-2016 AUP74_RS05820 3661e00c5291bf53ec49fa8b95cdd86e 634 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 26 126 7.4E-10 T 11-11-2016 AUP74_RS05820 3661e00c5291bf53ec49fa8b95cdd86e 634 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 215 331 5.1E-39 T 11-11-2016 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 AUP74_RS12800 58434dd597cd114e573ed75474703d2f 780 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 24 196 5.0E-41 T 11-11-2016 IPR025199 DNA translocase FtsK, 4TM region AUP74_RS12800 58434dd597cd114e573ed75474703d2f 780 SUPERFAMILY SSF52540 362 677 1.59E-52 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS12800 58434dd597cd114e573ed75474703d2f 780 Gene3D G3DSA:3.40.50.300 363 675 1.5E-95 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS12800 58434dd597cd114e573ed75474703d2f 780 SUPERFAMILY SSF46785 714 778 2.07E-22 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS12800 58434dd597cd114e573ed75474703d2f 780 SMART SM00843 714 779 3.7E-41 T 11-11-2016 IPR018541 FtsK gamma domain AUP74_RS12800 58434dd597cd114e573ed75474703d2f 780 Pfam PF09397 Ftsk gamma domain 716 776 9.6E-28 T 11-11-2016 IPR018541 FtsK gamma domain AUP74_RS12800 58434dd597cd114e573ed75474703d2f 780 Pfam PF01580 FtsK/SpoIIIE family 389 607 3.7E-68 T 11-11-2016 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 AUP74_RS00785 36c5aaf9ccfbeb404d116eaf9e658d76 426 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 189 332 1.3E-13 T 11-11-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AUP74_RS00785 36c5aaf9ccfbeb404d116eaf9e658d76 426 Pfam PF13533 Biotin-lipoyl like 94 130 3.4E-5 T 11-11-2016 AUP74_RS00785 36c5aaf9ccfbeb404d116eaf9e658d76 426 Gene3D G3DSA:2.40.50.100 236 272 8.3E-11 T 11-11-2016 AUP74_RS00785 36c5aaf9ccfbeb404d116eaf9e658d76 426 Gene3D G3DSA:2.40.50.100 82 114 8.3E-11 T 11-11-2016 AUP74_RS00785 36c5aaf9ccfbeb404d116eaf9e658d76 426 SUPERFAMILY SSF111369 75 177 1.44E-5 T 11-11-2016 AUP74_RS12725 e6b3cd1c2e1550ca946ae4301374ee2f 141 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 13 82 3.0E-4 T 11-11-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 AUP74_RS12725 e6b3cd1c2e1550ca946ae4301374ee2f 141 Gene3D G3DSA:2.60.15.10 5 84 4.9E-12 T 11-11-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 AUP74_RS12725 e6b3cd1c2e1550ca946ae4301374ee2f 141 SUPERFAMILY SSF51344 5 85 1.7E-14 T 11-11-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 AUP74_RS12725 e6b3cd1c2e1550ca946ae4301374ee2f 141 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 4 136 10.601 T 11-11-2016 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 AUP74_RS12725 e6b3cd1c2e1550ca946ae4301374ee2f 141 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 6 84 1.4E-14 T 11-11-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 AUP74_RS12300 5af213d2787066f316ede29f0abd2e72 545 SUPERFAMILY SSF54373 207 303 2.04E-35 T 11-11-2016 AUP74_RS12300 5af213d2787066f316ede29f0abd2e72 545 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 442 542 8.9E-51 T 11-11-2016 IPR007859 ETF-QO/FixX GO:0051536|GO:0055114 Reactome: R-HSA-611105 AUP74_RS12300 5af213d2787066f316ede29f0abd2e72 545 Gene3D G3DSA:3.50.50.60 8 46 1.1E-48 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS12300 5af213d2787066f316ede29f0abd2e72 545 Gene3D G3DSA:3.50.50.60 113 218 1.1E-48 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS12300 5af213d2787066f316ede29f0abd2e72 545 Gene3D G3DSA:3.50.50.60 305 443 1.1E-48 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS12300 5af213d2787066f316ede29f0abd2e72 545 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 175 190 5.8E-5 T 11-11-2016 AUP74_RS12300 5af213d2787066f316ede29f0abd2e72 545 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 9 31 5.8E-5 T 11-11-2016 AUP74_RS12300 5af213d2787066f316ede29f0abd2e72 545 SUPERFAMILY SSF54862 446 545 4.85E-31 T 11-11-2016 AUP74_RS12300 5af213d2787066f316ede29f0abd2e72 545 Pfam PF13450 NAD(P)-binding Rossmann-like domain 12 53 4.8E-8 T 11-11-2016 AUP74_RS12300 5af213d2787066f316ede29f0abd2e72 545 SUPERFAMILY SSF51905 304 444 6.87E-59 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS12300 5af213d2787066f316ede29f0abd2e72 545 SUPERFAMILY SSF51905 4 206 6.87E-59 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS03690 478aa0c4559d59f12ef7b5b7267dff37 145 Gene3D G3DSA:3.50.80.10 2 145 4.2E-53 T 11-11-2016 IPR023509 D-Tyr tRNAtyr deacylase-like domain AUP74_RS03690 478aa0c4559d59f12ef7b5b7267dff37 145 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 3 145 7.7E-60 T 11-11-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 AUP74_RS03690 478aa0c4559d59f12ef7b5b7267dff37 145 SUPERFAMILY SSF69500 2 144 2.49E-52 T 11-11-2016 IPR023509 D-Tyr tRNAtyr deacylase-like domain AUP74_RS03690 478aa0c4559d59f12ef7b5b7267dff37 145 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 4 144 4.0E-49 T 11-11-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 AUP74_RS03690 478aa0c4559d59f12ef7b5b7267dff37 145 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 33.518 T 11-11-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 AUP74_RS01620 d9f2a0f7d733bcaf2f27f0159c3acc2c 299 TIGRFAM TIGR01692 HIBADH: 3-hydroxyisobutyrate dehydrogenase 6 294 3.1E-119 T 11-11-2016 IPR011548 3-hydroxyisobutyrate dehydrogenase GO:0008442|GO:0051287|GO:0055114 KEGG: 00280+1.1.1.31|Reactome: R-HSA-70895 AUP74_RS01620 d9f2a0f7d733bcaf2f27f0159c3acc2c 299 SUPERFAMILY SSF48179 163 294 4.65E-37 T 11-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AUP74_RS01620 d9f2a0f7d733bcaf2f27f0159c3acc2c 299 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 162 1.2E-47 T 11-11-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 AUP74_RS01620 d9f2a0f7d733bcaf2f27f0159c3acc2c 299 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 292 9.4E-32 T 11-11-2016 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 AUP74_RS01620 d9f2a0f7d733bcaf2f27f0159c3acc2c 299 Gene3D G3DSA:3.40.50.720 2 163 5.1E-56 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS01620 d9f2a0f7d733bcaf2f27f0159c3acc2c 299 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 6 19 - T 11-11-2016 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 AUP74_RS01620 d9f2a0f7d733bcaf2f27f0159c3acc2c 299 PIRSF PIRSF000103 1 299 4.6E-79 T 11-11-2016 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 AUP74_RS01620 d9f2a0f7d733bcaf2f27f0159c3acc2c 299 SUPERFAMILY SSF51735 1 162 6.52E-45 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS01620 d9f2a0f7d733bcaf2f27f0159c3acc2c 299 Gene3D G3DSA:1.10.1040.10 164 295 3.2E-41 T 11-11-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AUP74_RS05520 f9c689d4b2340160f4723f77824cb045 386 SUPERFAMILY SSF53474 11 372 2.87E-102 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS05520 f9c689d4b2340160f4723f77824cb045 386 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 20 373 9.8E-139 T 11-11-2016 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 AUP74_RS05520 f9c689d4b2340160f4723f77824cb045 386 Pfam PF00561 alpha/beta hydrolase fold 49 359 1.7E-32 T 11-11-2016 IPR000073 Alpha/beta hydrolase fold-1 AUP74_RS05520 f9c689d4b2340160f4723f77824cb045 386 Hamap MF_00296 Homoserine O-acetyltransferase [metX]. 6 375 48.474 T 11-11-2016 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 AUP74_RS05520 f9c689d4b2340160f4723f77824cb045 386 PIRSF PIRSF000443 2 382 2.1E-131 T 11-11-2016 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 AUP74_RS05520 f9c689d4b2340160f4723f77824cb045 386 Gene3D G3DSA:3.40.50.1820 243 359 3.8E-35 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS05520 f9c689d4b2340160f4723f77824cb045 386 Gene3D G3DSA:3.40.50.1820 31 206 3.8E-35 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS10115 85ec340a6037b51e3fa1f566ee530175 352 Hamap MF_00959 RNA polymerase sigma factor RpoS [rpoS]. 31 349 39.99 T 11-11-2016 IPR012761 RNA polymerase sigma factor RpoS GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS10115 85ec340a6037b51e3fa1f566ee530175 352 Gene3D G3DSA:1.10.10.10 188 237 7.4E-15 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS10115 85ec340a6037b51e3fa1f566ee530175 352 Pfam PF00140 Sigma-70 factor, region 1.2 77 109 1.0E-12 T 11-11-2016 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS10115 85ec340a6037b51e3fa1f566ee530175 352 Pfam PF04539 Sigma-70 region 3 195 269 5.0E-21 T 11-11-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS10115 85ec340a6037b51e3fa1f566ee530175 352 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 308 334 - T 11-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS10115 85ec340a6037b51e3fa1f566ee530175 352 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 111 337 2.2E-35 T 11-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS10115 85ec340a6037b51e3fa1f566ee530175 352 Gene3D G3DSA:1.10.10.10 279 344 1.2E-22 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS10115 85ec340a6037b51e3fa1f566ee530175 352 SUPERFAMILY SSF88659 246 343 7.29E-24 T 11-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS10115 85ec340a6037b51e3fa1f566ee530175 352 SUPERFAMILY SSF88659 188 261 1.22E-14 T 11-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS10115 85ec340a6037b51e3fa1f566ee530175 352 PRINTS PR00046 Major sigma-70 factor signature 323 334 3.3E-26 T 11-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS10115 85ec340a6037b51e3fa1f566ee530175 352 PRINTS PR00046 Major sigma-70 factor signature 139 152 3.3E-26 T 11-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS10115 85ec340a6037b51e3fa1f566ee530175 352 PRINTS PR00046 Major sigma-70 factor signature 287 299 3.3E-26 T 11-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS10115 85ec340a6037b51e3fa1f566ee530175 352 PRINTS PR00046 Major sigma-70 factor signature 163 171 3.3E-26 T 11-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS10115 85ec340a6037b51e3fa1f566ee530175 352 PRINTS PR00046 Major sigma-70 factor signature 308 323 3.3E-26 T 11-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS10115 85ec340a6037b51e3fa1f566ee530175 352 Gene3D G3DSA:1.10.601.10 23 184 2.4E-58 T 11-11-2016 AUP74_RS10115 85ec340a6037b51e3fa1f566ee530175 352 TIGRFAM TIGR02394 rpoS_proteo: RNA polymerase sigma factor RpoS 73 348 1.4E-139 T 11-11-2016 IPR012761 RNA polymerase sigma factor RpoS GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS10115 85ec340a6037b51e3fa1f566ee530175 352 Pfam PF04542 Sigma-70 region 2 115 184 2.0E-21 T 11-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS10115 85ec340a6037b51e3fa1f566ee530175 352 Pfam PF04545 Sigma-70, region 4 283 336 3.9E-16 T 11-11-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS10115 85ec340a6037b51e3fa1f566ee530175 352 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 139 152 - T 11-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS10115 85ec340a6037b51e3fa1f566ee530175 352 SUPERFAMILY SSF88946 77 185 1.02E-45 T 11-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS09320 528553bff3b67ce82c5217715066d9a8 142 SUPERFAMILY SSF102400 1 139 8.89E-41 T 11-11-2016 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 AUP74_RS09320 528553bff3b67ce82c5217715066d9a8 142 Pfam PF04364 DNA polymerase III chi subunit, HolC 1 135 3.6E-37 T 11-11-2016 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 AUP74_RS09320 528553bff3b67ce82c5217715066d9a8 142 Gene3D G3DSA:3.40.50.10110 1 139 9.0E-42 T 11-11-2016 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 AUP74_RS00650 ccceebf3162a232daeb3d0a6dbccd087 926 Pfam PF07715 TonB-dependent Receptor Plug Domain 49 161 3.5E-26 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS00650 ccceebf3162a232daeb3d0a6dbccd087 926 SUPERFAMILY SSF56935 469 617 3.14E-96 T 11-11-2016 AUP74_RS00650 ccceebf3162a232daeb3d0a6dbccd087 926 SUPERFAMILY SSF56935 293 425 3.14E-96 T 11-11-2016 AUP74_RS00650 ccceebf3162a232daeb3d0a6dbccd087 926 SUPERFAMILY SSF56935 739 926 3.14E-96 T 11-11-2016 AUP74_RS00650 ccceebf3162a232daeb3d0a6dbccd087 926 SUPERFAMILY SSF56935 34 228 3.14E-96 T 11-11-2016 AUP74_RS00650 ccceebf3162a232daeb3d0a6dbccd087 926 SUPERFAMILY SSF56935 646 697 3.14E-96 T 11-11-2016 AUP74_RS00650 ccceebf3162a232daeb3d0a6dbccd087 926 Gene3D G3DSA:2.40.170.20 466 605 2.4E-74 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS00650 ccceebf3162a232daeb3d0a6dbccd087 926 Gene3D G3DSA:2.40.170.20 366 412 2.4E-74 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS00650 ccceebf3162a232daeb3d0a6dbccd087 926 Gene3D G3DSA:2.40.170.20 165 256 2.4E-74 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS00650 ccceebf3162a232daeb3d0a6dbccd087 926 Gene3D G3DSA:2.40.170.20 641 926 2.4E-74 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS00650 ccceebf3162a232daeb3d0a6dbccd087 926 Gene3D G3DSA:2.40.170.20 292 327 2.4E-74 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS00650 ccceebf3162a232daeb3d0a6dbccd087 926 Gene3D G3DSA:2.170.130.10 50 164 1.5E-38 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS00650 ccceebf3162a232daeb3d0a6dbccd087 926 Pfam PF00593 TonB dependent receptor 578 925 5.7E-26 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS01785 f986d4d9d9d18bce6a3d88bd91dc8fa6 583 Hamap MF_00747 Isocitrate dehydrogenase kinase/phosphatase [aceK]. 3 574 42.808 T 11-11-2016 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 AUP74_RS01785 f986d4d9d9d18bce6a3d88bd91dc8fa6 583 PIRSF PIRSF000719 2 579 5.9E-229 T 11-11-2016 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 AUP74_RS01785 f986d4d9d9d18bce6a3d88bd91dc8fa6 583 ProDom PD043552 KINASE KINASE/PHOSPHATASE ISOCITRATE DEHYDROGENASE 3.1.3.- IDH TRANSFERASE IDHK/P HYDROLASE ENZYME 11 576 9.0E-156 T 11-11-2016 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 AUP74_RS01785 f986d4d9d9d18bce6a3d88bd91dc8fa6 583 Pfam PF06315 Isocitrate dehydrogenase kinase/phosphatase (AceK) 11 570 1.4E-240 T 11-11-2016 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 AUP74_RS13280 b00e762532b283f602d08f18eef35b7d 466 Pfam PF01336 OB-fold nucleic acid binding domain 21 99 2.3E-8 T 11-11-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 AUP74_RS13280 b00e762532b283f602d08f18eef35b7d 466 Gene3D G3DSA:3.30.930.10 108 464 4.9E-116 T 11-11-2016 AUP74_RS13280 b00e762532b283f602d08f18eef35b7d 466 Gene3D G3DSA:2.40.50.140 15 104 1.8E-14 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS13280 b00e762532b283f602d08f18eef35b7d 466 Pfam PF00152 tRNA synthetases class II (D, K and N) 118 460 6.6E-87 T 11-11-2016 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS13280 b00e762532b283f602d08f18eef35b7d 466 SUPERFAMILY SSF50249 15 102 1.16E-14 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS13280 b00e762532b283f602d08f18eef35b7d 466 SUPERFAMILY SSF55681 96 465 6.43E-101 T 11-11-2016 AUP74_RS13280 b00e762532b283f602d08f18eef35b7d 466 PRINTS PR01042 Aspartyl-tRNA synthetase signature 208 220 7.4E-14 T 11-11-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS13280 b00e762532b283f602d08f18eef35b7d 466 PRINTS PR01042 Aspartyl-tRNA synthetase signature 421 435 7.4E-14 T 11-11-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS13280 b00e762532b283f602d08f18eef35b7d 466 PRINTS PR01042 Aspartyl-tRNA synthetase signature 381 397 7.4E-14 T 11-11-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS13280 b00e762532b283f602d08f18eef35b7d 466 PRINTS PR01042 Aspartyl-tRNA synthetase signature 224 237 7.4E-14 T 11-11-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS13280 b00e762532b283f602d08f18eef35b7d 466 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 6 466 45.826 T 11-11-2016 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 AUP74_RS13280 b00e762532b283f602d08f18eef35b7d 466 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 6 466 2.3E-202 T 11-11-2016 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 AUP74_RS09540 7309995270b144444986ef38651b2849 330 SUPERFAMILY SSF53686 13 318 4.85E-91 T 11-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme AUP74_RS09540 7309995270b144444986ef38651b2849 330 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 23 311 4.4E-79 T 11-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme AUP74_RS09540 7309995270b144444986ef38651b2849 330 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 49 62 - T 11-11-2016 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 AUP74_RS09540 7309995270b144444986ef38651b2849 330 Gene3D G3DSA:3.40.50.1100 76 322 3.7E-74 T 11-11-2016 AUP74_RS11550 91d9acf1dab35984f2a530d6bdc34673 207 SUPERFAMILY SSF47240 8 203 1.87E-78 T 11-11-2016 IPR009078 Ferritin-like superfamily AUP74_RS11550 91d9acf1dab35984f2a530d6bdc34673 207 PIRSF PIRSF020736 1 205 2.0E-90 T 11-11-2016 IPR010386 tRNA-hydroxylase MiaE GO:0006400|GO:0045301 AUP74_RS11550 91d9acf1dab35984f2a530d6bdc34673 207 Pfam PF06175 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) 61 200 3.5E-62 T 11-11-2016 IPR010386 tRNA-hydroxylase MiaE GO:0006400|GO:0045301 AUP74_RS11550 91d9acf1dab35984f2a530d6bdc34673 207 Pfam PF06175 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) 8 58 6.2E-16 T 11-11-2016 IPR010386 tRNA-hydroxylase MiaE GO:0006400|GO:0045301 AUP74_RS11550 91d9acf1dab35984f2a530d6bdc34673 207 Gene3D G3DSA:1.20.1260.10 7 204 3.2E-87 T 11-11-2016 IPR012347 Ferritin-related AUP74_RS12165 b9045c4bd9bd809c4b652ba20a24db1c 467 Pfam PF00270 DEAD/DEAH box helicase 34 199 2.8E-47 T 11-11-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AUP74_RS12165 b9045c4bd9bd809c4b652ba20a24db1c 467 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 158 166 - T 11-11-2016 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site AUP74_RS12165 b9045c4bd9bd809c4b652ba20a24db1c 467 Pfam PF00271 Helicase conserved C-terminal domain 237 344 1.9E-26 T 11-11-2016 IPR001650 Helicase, C-terminal AUP74_RS12165 b9045c4bd9bd809c4b652ba20a24db1c 467 SUPERFAMILY SSF52540 79 364 1.2E-73 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS12165 b9045c4bd9bd809c4b652ba20a24db1c 467 Gene3D G3DSA:3.40.50.300 5 214 6.8E-80 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS12165 b9045c4bd9bd809c4b652ba20a24db1c 467 Pfam PF03880 DbpA RNA binding domain 393 463 3.8E-24 T 11-11-2016 IPR005580 DbpA, RNA-binding domain AUP74_RS12165 b9045c4bd9bd809c4b652ba20a24db1c 467 SMART SM00487 29 226 2.9E-60 T 11-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain AUP74_RS12165 b9045c4bd9bd809c4b652ba20a24db1c 467 Gene3D G3DSA:3.40.50.300 219 376 1.7E-48 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS12165 b9045c4bd9bd809c4b652ba20a24db1c 467 SMART SM00490 263 344 4.0E-30 T 11-11-2016 IPR001650 Helicase, C-terminal AUP74_RS13425 214405a15b5425ba0dee4e0e65450ad4 247 Hamap MF_01589 Carboxy-S-adenosyl-L-methionine synthase [cmoA]. 3 242 41.029 T 11-11-2016 IPR005271 Carboxy-S-adenosyl-L-methionine synthase GO:0002098 AUP74_RS13425 214405a15b5425ba0dee4e0e65450ad4 247 PIRSF PIRSF006325 1 243 1.8E-99 T 11-11-2016 IPR005271 Carboxy-S-adenosyl-L-methionine synthase GO:0002098 AUP74_RS13425 214405a15b5425ba0dee4e0e65450ad4 247 TIGRFAM TIGR00740 TIGR00740: tRNA (cmo5U34)-methyltransferase 4 242 3.3E-93 T 11-11-2016 IPR005271 Carboxy-S-adenosyl-L-methionine synthase GO:0002098 AUP74_RS13425 214405a15b5425ba0dee4e0e65450ad4 247 Pfam PF13649 Methyltransferase domain 62 158 2.6E-10 T 11-11-2016 AUP74_RS13425 214405a15b5425ba0dee4e0e65450ad4 247 SUPERFAMILY SSF53335 20 242 4.34E-37 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS13425 214405a15b5425ba0dee4e0e65450ad4 247 Gene3D G3DSA:3.40.50.150 19 242 3.8E-57 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS05335 cec6048f1d5826d5d86663451485799e 138 PRINTS PR00607 Class IE cytochrome C signature 80 90 5.4E-17 T 11-11-2016 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 AUP74_RS05335 cec6048f1d5826d5d86663451485799e 138 PRINTS PR00607 Class IE cytochrome C signature 108 120 5.4E-17 T 11-11-2016 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 AUP74_RS05335 cec6048f1d5826d5d86663451485799e 138 PRINTS PR00607 Class IE cytochrome C signature 69 80 5.4E-17 T 11-11-2016 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 AUP74_RS05335 cec6048f1d5826d5d86663451485799e 138 PRINTS PR00607 Class IE cytochrome C signature 123 134 5.4E-17 T 11-11-2016 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 AUP74_RS05335 cec6048f1d5826d5d86663451485799e 138 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 60 133 4.8E-19 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS05335 cec6048f1d5826d5d86663451485799e 138 SUPERFAMILY SSF46626 59 135 7.45E-21 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS05335 cec6048f1d5826d5d86663451485799e 138 Gene3D G3DSA:1.10.760.10 59 135 7.5E-37 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS14050 e1b9d16975b60079160209c067d82d86 268 SUPERFAMILY SSF160920 3 252 3.66E-98 T 11-11-2016 AUP74_RS14050 e1b9d16975b60079160209c067d82d86 268 Pfam PF07286 Protein of unknown function (DUF1445) 109 251 8.2E-61 T 11-11-2016 IPR009906 Protein of unknown function DUF1445 AUP74_RS14050 e1b9d16975b60079160209c067d82d86 268 PIRSF PIRSF029755 1 260 7.7E-102 T 11-11-2016 IPR016938 Uncharacterised protein family UPF0317 AUP74_RS14050 e1b9d16975b60079160209c067d82d86 268 Gene3D G3DSA:3.40.1640.10 2 161 6.9E-56 T 11-11-2016 AUP74_RS16215 757561c9418e380708e02c645743fdf3 388 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 1 380 7.6E-144 T 11-11-2016 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 AUP74_RS16215 757561c9418e380708e02c645743fdf3 388 Pfam PF00202 Aminotransferase class-III 5 378 2.1E-115 T 11-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AUP74_RS16215 757561c9418e380708e02c645743fdf3 388 Gene3D G3DSA:3.40.640.10 43 274 7.3E-86 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AUP74_RS16215 757561c9418e380708e02c645743fdf3 388 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 1 381 43.802 T 11-11-2016 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 AUP74_RS16215 757561c9418e380708e02c645743fdf3 388 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 207 244 - T 11-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AUP74_RS16215 757561c9418e380708e02c645743fdf3 388 Gene3D G3DSA:3.90.1150.10 275 382 3.3E-35 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS16215 757561c9418e380708e02c645743fdf3 388 SUPERFAMILY SSF53383 2 380 1.04E-122 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase AUP74_RS16625 802bf7a164fb39dc860e9bd99f7b79be 189 SUPERFAMILY SSF51283 3 188 5.1E-51 T 11-11-2016 IPR029054 dUTPase-like AUP74_RS16625 802bf7a164fb39dc860e9bd99f7b79be 189 Hamap MF_00146 Deoxycytidine triphosphate deaminase [dcd]. 1 189 27.784 T 11-11-2016 IPR011962 Deoxycytidine triphosphate deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 AUP74_RS16625 802bf7a164fb39dc860e9bd99f7b79be 189 Gene3D G3DSA:2.70.40.10 3 188 1.6E-67 T 11-11-2016 IPR029054 dUTPase-like AUP74_RS16625 802bf7a164fb39dc860e9bd99f7b79be 189 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 4 188 2.1E-48 T 11-11-2016 IPR011962 Deoxycytidine triphosphate deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 AUP74_RS16625 802bf7a164fb39dc860e9bd99f7b79be 189 Pfam PF00692 dUTPase 81 184 1.1E-7 T 11-11-2016 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 AUP74_RS04200 05705f4e55dd4ff2a8dc11ecd576251e 428 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 226 426 2.1E-22 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AUP74_RS04200 05705f4e55dd4ff2a8dc11ecd576251e 428 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 186 425 1.3E-66 T 11-11-2016 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 AUP74_RS04200 05705f4e55dd4ff2a8dc11ecd576251e 428 Pfam PF11812 Domain of unknown function (DUF3333) 14 156 1.0E-46 T 11-11-2016 IPR024573 Domain of unknown function DUF3333 AUP74_RS04200 05705f4e55dd4ff2a8dc11ecd576251e 428 Gene3D G3DSA:1.10.3720.10 185 427 2.2E-46 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AUP74_RS04200 05705f4e55dd4ff2a8dc11ecd576251e 428 SUPERFAMILY SSF161098 175 414 1.57E-39 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AUP74_RS02750 91a544ec1ee843a1e6676f586ae42641 601 Gene3D G3DSA:3.40.640.10 171 380 6.5E-34 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AUP74_RS02750 91a544ec1ee843a1e6676f586ae42641 601 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 69 3.9E-5 T 11-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AUP74_RS02750 91a544ec1ee843a1e6676f586ae42641 601 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 53 3.9E-5 T 11-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AUP74_RS02750 91a544ec1ee843a1e6676f586ae42641 601 SUPERFAMILY SSF46785 8 81 4.28E-18 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS02750 91a544ec1ee843a1e6676f586ae42641 601 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 79 4.1E-13 T 11-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AUP74_RS02750 91a544ec1ee843a1e6676f586ae42641 601 SMART SM00345 20 79 4.6E-12 T 11-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AUP74_RS02750 91a544ec1ee843a1e6676f586ae42641 601 SUPERFAMILY SSF53383 131 482 5.39E-57 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase AUP74_RS02750 91a544ec1ee843a1e6676f586ae42641 601 Gene3D G3DSA:1.10.10.10 8 80 1.0E-22 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS06440 f424bf32b24b83b6fc5fc6c22b4e34e5 221 SUPERFAMILY SSF51366 4 217 1.31E-75 T 11-11-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 AUP74_RS06440 f424bf32b24b83b6fc5fc6c22b4e34e5 221 PIRSF PIRSF001461 1 221 8.3E-101 T 11-11-2016 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 AUP74_RS06440 f424bf32b24b83b6fc5fc6c22b4e34e5 221 Gene3D G3DSA:3.20.20.70 2 220 2.1E-95 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS06440 f424bf32b24b83b6fc5fc6c22b4e34e5 221 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 33 47 - T 11-11-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 AUP74_RS06440 f424bf32b24b83b6fc5fc6c22b4e34e5 221 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 5 216 3.3E-95 T 11-11-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 AUP74_RS06440 f424bf32b24b83b6fc5fc6c22b4e34e5 221 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 136 158 - T 11-11-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 AUP74_RS06440 f424bf32b24b83b6fc5fc6c22b4e34e5 221 Pfam PF00834 Ribulose-phosphate 3 epimerase family 5 203 1.0E-87 T 11-11-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 AUP74_RS10180 289f8982946eefa3682daa5c411a7a7a 261 Gene3D G3DSA:3.40.50.720 5 259 9.3E-82 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS10180 289f8982946eefa3682daa5c411a7a7a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 2.8E-39 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS10180 289f8982946eefa3682daa5c411a7a7a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 2.8E-39 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS10180 289f8982946eefa3682daa5c411a7a7a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 2.8E-39 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS10180 289f8982946eefa3682daa5c411a7a7a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 2.8E-39 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS10180 289f8982946eefa3682daa5c411a7a7a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 2.8E-39 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS10180 289f8982946eefa3682daa5c411a7a7a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 2.8E-39 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS10180 289f8982946eefa3682daa5c411a7a7a 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 259 3.5E-65 T 11-11-2016 AUP74_RS10180 289f8982946eefa3682daa5c411a7a7a 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 1.6E-12 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS10180 289f8982946eefa3682daa5c411a7a7a 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 1.6E-12 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS10180 289f8982946eefa3682daa5c411a7a7a 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 1.6E-12 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS10180 289f8982946eefa3682daa5c411a7a7a 261 SUPERFAMILY SSF51735 6 260 1.31E-78 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS10180 289f8982946eefa3682daa5c411a7a7a 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 11-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AUP74_RS01360 702870a9b90971d72a473ce16d35ca1c 145 Pfam PF10116 Protein required for attachment to host cells 5 141 1.2E-37 T 11-11-2016 IPR019291 Host attachment protein AUP74_RS13255 0a34080b9e6a4199a62c1816019cbec8 200 Gene3D G3DSA:2.60.300.12 6 103 3.4E-17 T 11-11-2016 IPR000361 FeS cluster biogenesis AUP74_RS13255 0a34080b9e6a4199a62c1816019cbec8 200 Pfam PF01106 NifU-like domain 120 186 2.3E-21 T 11-11-2016 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 AUP74_RS13255 0a34080b9e6a4199a62c1816019cbec8 200 Hamap MF_01637 Fe/S biogenesis protein NfuA [nfuA]. 9 200 40.222 T 11-11-2016 IPR017726 Fe/S biogenesis protein NfuA GO:0016226|GO:0051539|GO:0051604 AUP74_RS13255 0a34080b9e6a4199a62c1816019cbec8 200 SUPERFAMILY SSF117916 104 194 5.67E-25 T 11-11-2016 AUP74_RS13255 0a34080b9e6a4199a62c1816019cbec8 200 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 127 186 4.0E-22 T 11-11-2016 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 AUP74_RS13255 0a34080b9e6a4199a62c1816019cbec8 200 SUPERFAMILY SSF89360 5 103 1.33E-20 T 11-11-2016 IPR000361 FeS cluster biogenesis AUP74_RS13255 0a34080b9e6a4199a62c1816019cbec8 200 Pfam PF01521 Iron-sulphur cluster biosynthesis 9 104 3.0E-10 T 11-11-2016 IPR000361 FeS cluster biogenesis AUP74_RS13255 0a34080b9e6a4199a62c1816019cbec8 200 TIGRFAM TIGR03341 YhgI_GntY: IscR-regulated protein YhgI 10 200 3.6E-92 T 11-11-2016 IPR017726 Fe/S biogenesis protein NfuA GO:0016226|GO:0051539|GO:0051604 AUP74_RS02880 f34efebd3a60a9abb8f4118cba3c178b 354 Gene3D G3DSA:3.20.20.70 1 335 1.2E-109 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS02880 f34efebd3a60a9abb8f4118cba3c178b 354 TIGRFAM TIGR01521 FruBisAldo_II_B: fructose-bisphosphate aldolase, class II, Calvin cycle subtype 3 349 1.9E-204 T 11-11-2016 IPR006412 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 AUP74_RS02880 f34efebd3a60a9abb8f4118cba3c178b 354 Pfam PF01116 Fructose-bisphosphate aldolase class-II 5 327 2.9E-92 T 11-11-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 AUP74_RS02880 f34efebd3a60a9abb8f4118cba3c178b 354 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 139 150 - T 11-11-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 AUP74_RS02880 f34efebd3a60a9abb8f4118cba3c178b 354 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 73 85 - T 11-11-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 AUP74_RS02880 f34efebd3a60a9abb8f4118cba3c178b 354 PIRSF PIRSF001359 1 329 1.8E-82 T 11-11-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 AUP74_RS02880 f34efebd3a60a9abb8f4118cba3c178b 354 SUPERFAMILY SSF51569 3 328 1.9E-107 T 11-11-2016 AUP74_RS02880 f34efebd3a60a9abb8f4118cba3c178b 354 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 329 4.2E-96 T 11-11-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 AUP74_RS04620 5455c838c9b98cccb6c2747695d8d118 413 SUPERFAMILY SSF53187 8 225 3.71E-97 T 11-11-2016 AUP74_RS04620 5455c838c9b98cccb6c2747695d8d118 413 SUPERFAMILY SSF53187 338 412 3.71E-97 T 11-11-2016 AUP74_RS04620 5455c838c9b98cccb6c2747695d8d118 413 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 12 409 5.5E-123 T 11-11-2016 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 AUP74_RS04620 5455c838c9b98cccb6c2747695d8d118 413 Gene3D G3DSA:3.40.630.10 353 412 3.6E-117 T 11-11-2016 AUP74_RS04620 5455c838c9b98cccb6c2747695d8d118 413 Gene3D G3DSA:3.40.630.10 6 227 3.6E-117 T 11-11-2016 AUP74_RS04620 5455c838c9b98cccb6c2747695d8d118 413 Pfam PF07687 Peptidase dimerisation domain 212 316 7.7E-8 T 11-11-2016 IPR011650 Peptidase M20, dimerisation domain AUP74_RS04620 5455c838c9b98cccb6c2747695d8d118 413 Pfam PF01546 Peptidase family M20/M25/M40 82 408 8.0E-37 T 11-11-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 AUP74_RS04620 5455c838c9b98cccb6c2747695d8d118 413 SUPERFAMILY SSF55031 215 331 5.98E-26 T 11-11-2016 IPR011650 Peptidase M20, dimerisation domain AUP74_RS04620 5455c838c9b98cccb6c2747695d8d118 413 PIRSF PIRSF001235 6 413 6.5E-134 T 11-11-2016 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 AUP74_RS04620 5455c838c9b98cccb6c2747695d8d118 413 Gene3D G3DSA:3.30.70.360 228 331 1.4E-32 T 11-11-2016 IPR011650 Peptidase M20, dimerisation domain AUP74_RS05555 c82f7ec5dc8de639fe2f5350ffb42c56 89 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 3 73 2.4E-24 T 11-11-2016 IPR000504 RNA recognition motif domain GO:0003676 AUP74_RS05555 c82f7ec5dc8de639fe2f5350ffb42c56 89 Gene3D G3DSA:3.30.70.330 2 88 1.1E-31 T 11-11-2016 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 AUP74_RS05555 c82f7ec5dc8de639fe2f5350ffb42c56 89 SMART SM00360 2 75 2.5E-28 T 11-11-2016 IPR000504 RNA recognition motif domain GO:0003676 AUP74_RS05555 c82f7ec5dc8de639fe2f5350ffb42c56 89 SUPERFAMILY SSF54928 2 88 4.7E-32 T 11-11-2016 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 AUP74_RS02910 e25170634f028a213cd97af4f7460a68 945 Pfam PF05193 Peptidase M16 inactive domain 223 396 6.7E-28 T 11-11-2016 IPR007863 Peptidase M16, C-terminal AUP74_RS02910 e25170634f028a213cd97af4f7460a68 945 Pfam PF05193 Peptidase M16 inactive domain 664 841 1.1E-30 T 11-11-2016 IPR007863 Peptidase M16, C-terminal AUP74_RS02910 e25170634f028a213cd97af4f7460a68 945 SUPERFAMILY SSF63411 492 713 3.14E-43 T 11-11-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AUP74_RS02910 e25170634f028a213cd97af4f7460a68 945 SUPERFAMILY SSF63411 289 462 1.75E-25 T 11-11-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AUP74_RS02910 e25170634f028a213cd97af4f7460a68 945 SUPERFAMILY SSF63411 722 923 4.83E-31 T 11-11-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AUP74_RS02910 e25170634f028a213cd97af4f7460a68 945 SUPERFAMILY SSF63411 53 269 4.03E-55 T 11-11-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AUP74_RS02910 e25170634f028a213cd97af4f7460a68 945 Gene3D G3DSA:3.30.830.10 496 714 4.8E-43 T 11-11-2016 IPR011237 Peptidase M16 domain GO:0046872 AUP74_RS02910 e25170634f028a213cd97af4f7460a68 945 Gene3D G3DSA:3.30.830.10 52 269 1.2E-52 T 11-11-2016 IPR011237 Peptidase M16 domain GO:0046872 AUP74_RS02910 e25170634f028a213cd97af4f7460a68 945 Pfam PF00675 Insulinase (Peptidase family M16) 65 201 7.0E-16 T 11-11-2016 IPR011765 Peptidase M16, N-terminal AUP74_RS02910 e25170634f028a213cd97af4f7460a68 945 Pfam PF00675 Insulinase (Peptidase family M16) 508 630 3.8E-12 T 11-11-2016 IPR011765 Peptidase M16, N-terminal AUP74_RS02910 e25170634f028a213cd97af4f7460a68 945 Gene3D G3DSA:3.30.830.10 304 461 5.7E-13 T 11-11-2016 IPR011237 Peptidase M16 domain GO:0046872 AUP74_RS02910 e25170634f028a213cd97af4f7460a68 945 Gene3D G3DSA:3.30.830.10 721 910 1.5E-21 T 11-11-2016 IPR011237 Peptidase M16 domain GO:0046872 AUP74_RS04115 1ab7d9a4c916863646abde6a16e58ab5 307 Gene3D G3DSA:3.40.190.10 176 277 1.8E-31 T 11-11-2016 AUP74_RS04115 1ab7d9a4c916863646abde6a16e58ab5 307 Gene3D G3DSA:3.40.190.10 93 175 2.1E-17 T 11-11-2016 AUP74_RS04115 1ab7d9a4c916863646abde6a16e58ab5 307 SUPERFAMILY SSF53850 87 302 3.62E-42 T 11-11-2016 AUP74_RS04115 1ab7d9a4c916863646abde6a16e58ab5 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.9E-8 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS04115 1ab7d9a4c916863646abde6a16e58ab5 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.9E-8 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS04115 1ab7d9a4c916863646abde6a16e58ab5 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.9E-8 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS04115 1ab7d9a4c916863646abde6a16e58ab5 307 Gene3D G3DSA:1.10.10.10 1 82 1.2E-25 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS04115 1ab7d9a4c916863646abde6a16e58ab5 307 SUPERFAMILY SSF46785 1 84 1.01E-20 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS04115 1ab7d9a4c916863646abde6a16e58ab5 307 Pfam PF03466 LysR substrate binding domain 87 299 8.2E-48 T 11-11-2016 IPR005119 LysR, substrate-binding AUP74_RS04115 1ab7d9a4c916863646abde6a16e58ab5 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.0E-18 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS12220 e1dc197cee0239bf36bd157f001b4430 338 Pfam PF01565 FAD binding domain 21 152 2.4E-23 T 11-11-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AUP74_RS12220 e1dc197cee0239bf36bd157f001b4430 338 SUPERFAMILY SSF56194 212 337 1.83E-41 T 11-11-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AUP74_RS12220 e1dc197cee0239bf36bd157f001b4430 338 SUPERFAMILY SSF56176 7 194 1.54E-42 T 11-11-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 AUP74_RS12220 e1dc197cee0239bf36bd157f001b4430 338 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 338 78.518 T 11-11-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AUP74_RS12220 e1dc197cee0239bf36bd157f001b4430 338 Gene3D G3DSA:3.90.78.10 239 337 3.3E-37 T 11-11-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AUP74_RS12220 e1dc197cee0239bf36bd157f001b4430 338 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 8 336 3.0E-63 T 11-11-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AUP74_RS12220 e1dc197cee0239bf36bd157f001b4430 338 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 214 336 2.9E-32 T 11-11-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AUP74_RS12220 e1dc197cee0239bf36bd157f001b4430 338 Gene3D G3DSA:3.30.43.10 7 70 2.4E-21 T 11-11-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 AUP74_RS12220 e1dc197cee0239bf36bd157f001b4430 338 Gene3D G3DSA:3.30.465.10 75 238 1.0E-50 T 11-11-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 AUP74_RS12320 750fd0d7ad7b5d33c8fddca42f664641 634 Pfam PF03958 Bacterial type II/III secretion system short domain 244 318 7.4E-15 T 11-11-2016 IPR005644 NolW-like AUP74_RS12320 750fd0d7ad7b5d33c8fddca42f664641 634 Pfam PF03958 Bacterial type II/III secretion system short domain 106 165 1.1E-10 T 11-11-2016 IPR005644 NolW-like AUP74_RS12320 750fd0d7ad7b5d33c8fddca42f664641 634 Pfam PF03958 Bacterial type II/III secretion system short domain 170 237 3.6E-13 T 11-11-2016 IPR005644 NolW-like AUP74_RS12320 750fd0d7ad7b5d33c8fddca42f664641 634 Pfam PF00263 Bacterial type II and III secretion system protein 404 569 3.7E-49 T 11-11-2016 IPR004846 Type II/III secretion system GO:0009306 AUP74_RS12320 750fd0d7ad7b5d33c8fddca42f664641 634 PRINTS PR00811 Bacterial general secretion pathway protein D signature 557 571 3.6E-31 T 11-11-2016 IPR001775 GspD/PilQ family AUP74_RS12320 750fd0d7ad7b5d33c8fddca42f664641 634 PRINTS PR00811 Bacterial general secretion pathway protein D signature 534 552 3.6E-31 T 11-11-2016 IPR001775 GspD/PilQ family AUP74_RS12320 750fd0d7ad7b5d33c8fddca42f664641 634 PRINTS PR00811 Bacterial general secretion pathway protein D signature 399 423 3.6E-31 T 11-11-2016 IPR001775 GspD/PilQ family AUP74_RS12320 750fd0d7ad7b5d33c8fddca42f664641 634 PRINTS PR00811 Bacterial general secretion pathway protein D signature 434 444 3.6E-31 T 11-11-2016 IPR001775 GspD/PilQ family AUP74_RS12320 750fd0d7ad7b5d33c8fddca42f664641 634 PRINTS PR00811 Bacterial general secretion pathway protein D signature 318 328 3.6E-31 T 11-11-2016 IPR001775 GspD/PilQ family AUP74_RS12320 750fd0d7ad7b5d33c8fddca42f664641 634 TIGRFAM TIGR02517 type_II_gspD: type II secretion system protein D 11 571 1.3E-157 T 11-11-2016 IPR013356 Type II secretion system GspD GO:0008565|GO:0015627|GO:0015628|GO:0019867 AUP74_RS14895 7406a2345ab1857b2d31d0d3032eb3cb 1184 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 466 615 5.8E-6 T 11-11-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AUP74_RS14895 7406a2345ab1857b2d31d0d3032eb3cb 1184 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 740 926 2.4E-22 T 11-11-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 AUP74_RS14895 7406a2345ab1857b2d31d0d3032eb3cb 1184 Gene3D G3DSA:3.40.920.10 732 927 2.0E-15 T 11-11-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 AUP74_RS14895 7406a2345ab1857b2d31d0d3032eb3cb 1184 Gene3D G3DSA:3.40.50.970 499 679 5.5E-10 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS14895 7406a2345ab1857b2d31d0d3032eb3cb 1184 Gene3D G3DSA:3.40.50.970 437 494 0.001 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS14895 7406a2345ab1857b2d31d0d3032eb3cb 1184 SUPERFAMILY SSF52922 286 368 4.93E-5 T 11-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 AUP74_RS14895 7406a2345ab1857b2d31d0d3032eb3cb 1184 SUPERFAMILY SSF52518 446 629 5.81E-14 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS14895 7406a2345ab1857b2d31d0d3032eb3cb 1184 SUPERFAMILY SSF53323 732 973 1.06E-24 T 11-11-2016 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 AUP74_RS14895 7406a2345ab1857b2d31d0d3032eb3cb 1184 SUPERFAMILY SSF52518 58 214 5.71E-16 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS08450 068ac72d239cb13168d261fa84a93ae0 285 Pfam PF05036 Sporulation related domain 210 273 8.0E-12 T 11-11-2016 IPR007730 Sporulation-related domain GO:0042834 AUP74_RS08450 068ac72d239cb13168d261fa84a93ae0 285 SUPERFAMILY SSF110997 210 284 1.7E-10 T 11-11-2016 IPR007730 Sporulation-related domain GO:0042834 AUP74_RS08450 068ac72d239cb13168d261fa84a93ae0 285 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 85 258 2.5E-46 T 11-11-2016 IPR012997 Rare lipoprotein A AUP74_RS08450 068ac72d239cb13168d261fa84a93ae0 285 Gene3D G3DSA:2.40.40.10 123 170 2.4E-4 T 11-11-2016 IPR009009 RlpA-like protein, double-psi beta-barrel domain AUP74_RS08450 068ac72d239cb13168d261fa84a93ae0 285 Gene3D G3DSA:3.30.70.1070 209 277 8.5E-12 T 11-11-2016 IPR007730 Sporulation-related domain GO:0042834 AUP74_RS08450 068ac72d239cb13168d261fa84a93ae0 285 SUPERFAMILY SSF50685 74 172 2.89E-13 T 11-11-2016 IPR009009 RlpA-like protein, double-psi beta-barrel domain AUP74_RS08450 068ac72d239cb13168d261fa84a93ae0 285 Pfam PF03330 Lytic transglycolase 83 172 7.8E-29 T 11-11-2016 IPR009009 RlpA-like protein, double-psi beta-barrel domain AUP74_RS11020 9cafe78789623d1bae6e149c014f4d82 565 Pfam PF02225 PA domain 147 231 2.5E-5 T 11-11-2016 IPR003137 PA domain AUP74_RS11020 9cafe78789623d1bae6e149c014f4d82 565 Pfam PF04389 Peptidase family M28 313 520 2.1E-43 T 11-11-2016 IPR007484 Peptidase M28 AUP74_RS11020 9cafe78789623d1bae6e149c014f4d82 565 SUPERFAMILY SSF52025 146 234 4.05E-6 T 11-11-2016 AUP74_RS11020 9cafe78789623d1bae6e149c014f4d82 565 SUPERFAMILY SSF53187 297 542 1.14E-61 T 11-11-2016 AUP74_RS11020 9cafe78789623d1bae6e149c014f4d82 565 SUPERFAMILY SSF53187 43 87 1.14E-61 T 11-11-2016 AUP74_RS11020 9cafe78789623d1bae6e149c014f4d82 565 Gene3D G3DSA:3.40.630.10 310 549 5.7E-60 T 11-11-2016 AUP74_RS11020 9cafe78789623d1bae6e149c014f4d82 565 Gene3D G3DSA:3.40.630.10 35 99 5.7E-60 T 11-11-2016 AUP74_RS04135 91642ba711c2d8df76362b4a111285cb 436 Gene3D G3DSA:1.10.3860.10 2 412 1.0E-131 T 11-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AUP74_RS04135 91642ba711c2d8df76362b4a111285cb 436 SUPERFAMILY SSF118215 3 409 6.67E-119 T 11-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AUP74_RS04135 91642ba711c2d8df76362b4a111285cb 436 Pfam PF00375 Sodium:dicarboxylate symporter family 3 407 1.4E-129 T 11-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AUP74_RS04135 91642ba711c2d8df76362b4a111285cb 436 PRINTS PR00173 Glutamate-aspartate symporter signature 300 326 1.2E-44 T 11-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AUP74_RS04135 91642ba711c2d8df76362b4a111285cb 436 PRINTS PR00173 Glutamate-aspartate symporter signature 198 217 1.2E-44 T 11-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AUP74_RS04135 91642ba711c2d8df76362b4a111285cb 436 PRINTS PR00173 Glutamate-aspartate symporter signature 1 20 1.2E-44 T 11-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AUP74_RS04135 91642ba711c2d8df76362b4a111285cb 436 PRINTS PR00173 Glutamate-aspartate symporter signature 87 112 1.2E-44 T 11-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AUP74_RS04135 91642ba711c2d8df76362b4a111285cb 436 PRINTS PR00173 Glutamate-aspartate symporter signature 335 354 1.2E-44 T 11-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AUP74_RS04135 91642ba711c2d8df76362b4a111285cb 436 PRINTS PR00173 Glutamate-aspartate symporter signature 233 252 1.2E-44 T 11-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AUP74_RS04135 91642ba711c2d8df76362b4a111285cb 436 PRINTS PR00173 Glutamate-aspartate symporter signature 362 382 1.2E-44 T 11-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AUP74_RS03825 50656e8d1ceea4646511dbd55f95edf6 179 PIRSF PIRSF039093 1 179 4.2E-89 T 11-11-2016 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 AUP74_RS03825 50656e8d1ceea4646511dbd55f95edf6 179 SUPERFAMILY SSF56235 3 177 1.4E-58 T 11-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal AUP74_RS03825 50656e8d1ceea4646511dbd55f95edf6 179 Pfam PF00227 Proteasome subunit 5 175 2.7E-22 T 11-11-2016 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 AUP74_RS03825 50656e8d1ceea4646511dbd55f95edf6 179 Gene3D G3DSA:3.60.20.10 7 177 4.2E-85 T 11-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal AUP74_RS03825 50656e8d1ceea4646511dbd55f95edf6 179 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 6 177 41.744 T 11-11-2016 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 AUP74_RS03825 50656e8d1ceea4646511dbd55f95edf6 179 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 7 177 1.2E-86 T 11-11-2016 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 AUP74_RS01265 fc7e095526e4a5dc633003899459a529 699 Gene3D G3DSA:2.40.170.20 176 699 6.4E-111 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS01265 fc7e095526e4a5dc633003899459a529 699 SUPERFAMILY SSF56935 25 699 1.83E-112 T 11-11-2016 AUP74_RS01265 fc7e095526e4a5dc633003899459a529 699 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 40 - T 11-11-2016 IPR010916 TonB box, conserved site AUP74_RS01265 fc7e095526e4a5dc633003899459a529 699 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 62 696 4.9E-98 T 11-11-2016 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 AUP74_RS01265 fc7e095526e4a5dc633003899459a529 699 Pfam PF07715 TonB-dependent Receptor Plug Domain 61 158 4.3E-14 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS01265 fc7e095526e4a5dc633003899459a529 699 Pfam PF00593 TonB dependent receptor 468 698 7.0E-20 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS01265 fc7e095526e4a5dc633003899459a529 699 Gene3D G3DSA:2.170.130.10 40 167 1.2E-32 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS12850 26add08643a3eaf655343ad5f0f37c16 376 Gene3D G3DSA:3.40.50.620 5 216 4.6E-96 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS12850 26add08643a3eaf655343ad5f0f37c16 376 Gene3D G3DSA:2.30.30.280 217 284 2.3E-32 T 11-11-2016 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 AUP74_RS12850 26add08643a3eaf655343ad5f0f37c16 376 Gene3D G3DSA:2.40.30.10 286 367 6.6E-32 T 11-11-2016 AUP74_RS12850 26add08643a3eaf655343ad5f0f37c16 376 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 11 365 39.093 T 11-11-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 AUP74_RS12850 26add08643a3eaf655343ad5f0f37c16 376 SUPERFAMILY SSF52402 10 248 1.21E-58 T 11-11-2016 AUP74_RS12850 26add08643a3eaf655343ad5f0f37c16 376 Pfam PF03054 tRNA methyl transferase 11 364 6.4E-138 T 11-11-2016 AUP74_RS12850 26add08643a3eaf655343ad5f0f37c16 376 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 11 364 3.6E-141 T 11-11-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 AUP74_RS09135 1610c7f11b9e1ded63ec8bb33c07e1ee 64 TIGRFAM TIGR03412 iscX_yfhJ: FeS assembly protein IscX 2 64 6.2E-35 T 11-11-2016 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 AUP74_RS09135 1610c7f11b9e1ded63ec8bb33c07e1ee 64 Pfam PF04384 Iron-sulphur cluster assembly 1 63 2.4E-33 T 11-11-2016 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 AUP74_RS09135 1610c7f11b9e1ded63ec8bb33c07e1ee 64 Gene3D G3DSA:1.10.10.600 1 64 1.8E-33 T 11-11-2016 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 AUP74_RS09135 1610c7f11b9e1ded63ec8bb33c07e1ee 64 SUPERFAMILY SSF140319 1 62 1.26E-27 T 11-11-2016 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 AUP74_RS09135 1610c7f11b9e1ded63ec8bb33c07e1ee 64 PIRSF PIRSF039003 1 64 3.6E-35 T 11-11-2016 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 AUP74_RS07850 6aab1cf36c38cd4f9f154f1c7861bc3d 397 Gene3D G3DSA:3.40.640.10 49 278 1.5E-62 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AUP74_RS07850 6aab1cf36c38cd4f9f154f1c7861bc3d 397 SUPERFAMILY SSF53383 23 389 3.23E-97 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase AUP74_RS07850 6aab1cf36c38cd4f9f154f1c7861bc3d 397 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 237 250 - T 11-11-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 AUP74_RS07850 6aab1cf36c38cd4f9f154f1c7861bc3d 397 Pfam PF00155 Aminotransferase class I and II 36 385 1.6E-62 T 11-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AUP74_RS07850 6aab1cf36c38cd4f9f154f1c7861bc3d 397 Gene3D G3DSA:3.90.1150.10 279 391 1.4E-31 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS00045 402410820b1364f9acf6cbba4fca1775 447 Pfam PF03448 MgtE intracellular N domain 31 132 2.0E-26 T 11-11-2016 IPR006668 Magnesium transporter, MgtE intracellular domain AUP74_RS00045 402410820b1364f9acf6cbba4fca1775 447 Gene3D G3DSA:3.10.580.10 126 255 6.3E-22 T 11-11-2016 AUP74_RS00045 402410820b1364f9acf6cbba4fca1775 447 SMART SM00116 205 253 0.0056 T 11-11-2016 IPR000644 CBS domain AUP74_RS00045 402410820b1364f9acf6cbba4fca1775 447 SMART SM00116 141 194 20.0 T 11-11-2016 IPR000644 CBS domain AUP74_RS00045 402410820b1364f9acf6cbba4fca1775 447 SUPERFAMILY SSF158791 7 131 6.41E-31 T 11-11-2016 AUP74_RS00045 402410820b1364f9acf6cbba4fca1775 447 Gene3D G3DSA:1.25.60.10 5 125 3.2E-29 T 11-11-2016 AUP74_RS00045 402410820b1364f9acf6cbba4fca1775 447 SUPERFAMILY SSF161093 276 446 2.09E-45 T 11-11-2016 AUP74_RS00045 402410820b1364f9acf6cbba4fca1775 447 SMART SM00924 31 134 3.5E-36 T 11-11-2016 IPR006668 Magnesium transporter, MgtE intracellular domain AUP74_RS00045 402410820b1364f9acf6cbba4fca1775 447 Gene3D G3DSA:1.10.357.20 276 445 3.2E-46 T 11-11-2016 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 AUP74_RS00045 402410820b1364f9acf6cbba4fca1775 447 SUPERFAMILY SSF54631 133 273 3.92E-32 T 11-11-2016 AUP74_RS00045 402410820b1364f9acf6cbba4fca1775 447 TIGRFAM TIGR00400 mgtE: magnesium transporter 14 443 6.9E-92 T 11-11-2016 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 AUP74_RS00045 402410820b1364f9acf6cbba4fca1775 447 Pfam PF01769 Divalent cation transporter 318 439 1.8E-20 T 11-11-2016 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 AUP74_RS00045 402410820b1364f9acf6cbba4fca1775 447 Pfam PF00571 CBS domain 198 252 3.3E-7 T 11-11-2016 IPR000644 CBS domain AUP74_RS00045 402410820b1364f9acf6cbba4fca1775 447 Pfam PF00571 CBS domain 135 191 2.0E-5 T 11-11-2016 IPR000644 CBS domain AUP74_RS05455 d1b0c29edd6aaf35c827848d97bf2129 417 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 34 281 1.1E-72 T 11-11-2016 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 AUP74_RS05455 d1b0c29edd6aaf35c827848d97bf2129 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 57 75 2.6E-26 T 11-11-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AUP74_RS05455 d1b0c29edd6aaf35c827848d97bf2129 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 190 203 2.6E-26 T 11-11-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AUP74_RS05455 d1b0c29edd6aaf35c827848d97bf2129 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 77 89 2.6E-26 T 11-11-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AUP74_RS05455 d1b0c29edd6aaf35c827848d97bf2129 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 270 289 2.6E-26 T 11-11-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AUP74_RS05455 d1b0c29edd6aaf35c827848d97bf2129 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 368 381 2.6E-26 T 11-11-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AUP74_RS05455 d1b0c29edd6aaf35c827848d97bf2129 417 Gene3D G3DSA:3.20.20.10 36 266 2.1E-84 T 11-11-2016 IPR029066 PLP-binding barrel AUP74_RS05455 d1b0c29edd6aaf35c827848d97bf2129 417 PRINTS PR01181 Diaminopimelate decarboxylase signature 75 92 2.3E-30 T 11-11-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AUP74_RS05455 d1b0c29edd6aaf35c827848d97bf2129 417 PRINTS PR01181 Diaminopimelate decarboxylase signature 164 173 2.3E-30 T 11-11-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AUP74_RS05455 d1b0c29edd6aaf35c827848d97bf2129 417 PRINTS PR01181 Diaminopimelate decarboxylase signature 378 400 2.3E-30 T 11-11-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AUP74_RS05455 d1b0c29edd6aaf35c827848d97bf2129 417 PRINTS PR01181 Diaminopimelate decarboxylase signature 298 316 2.3E-30 T 11-11-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AUP74_RS05455 d1b0c29edd6aaf35c827848d97bf2129 417 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 15 411 42.167 T 11-11-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AUP74_RS05455 d1b0c29edd6aaf35c827848d97bf2129 417 SUPERFAMILY SSF50621 255 410 1.0E-50 T 11-11-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AUP74_RS05455 d1b0c29edd6aaf35c827848d97bf2129 417 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 286 388 2.8E-17 T 11-11-2016 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 AUP74_RS05455 d1b0c29edd6aaf35c827848d97bf2129 417 SUPERFAMILY SSF51419 26 281 3.27E-80 T 11-11-2016 IPR029066 PLP-binding barrel AUP74_RS05455 d1b0c29edd6aaf35c827848d97bf2129 417 Gene3D G3DSA:2.40.37.10 267 411 8.1E-46 T 11-11-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AUP74_RS05455 d1b0c29edd6aaf35c827848d97bf2129 417 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 57 75 - T 11-11-2016 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site AUP74_RS05455 d1b0c29edd6aaf35c827848d97bf2129 417 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 7 410 2.3E-160 T 11-11-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AUP74_RS10220 9857b24046764b80cd4192691c4b0a76 107 SUPERFAMILY SSF54862 1 97 2.88E-24 T 11-11-2016 AUP74_RS10220 9857b24046764b80cd4192691c4b0a76 107 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 11-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AUP74_RS10220 9857b24046764b80cd4192691c4b0a76 107 Gene3D G3DSA:3.30.70.20 4 101 3.7E-22 T 11-11-2016 AUP74_RS10220 9857b24046764b80cd4192691c4b0a76 107 PRINTS PR00354 7Fe ferredoxin signature 19 29 1.4E-18 T 11-11-2016 IPR000813 7Fe ferredoxin GO:0009055 AUP74_RS10220 9857b24046764b80cd4192691c4b0a76 107 PRINTS PR00354 7Fe ferredoxin signature 9 19 1.4E-18 T 11-11-2016 IPR000813 7Fe ferredoxin GO:0009055 AUP74_RS10220 9857b24046764b80cd4192691c4b0a76 107 PRINTS PR00354 7Fe ferredoxin signature 35 52 1.4E-18 T 11-11-2016 IPR000813 7Fe ferredoxin GO:0009055 AUP74_RS10220 9857b24046764b80cd4192691c4b0a76 107 Pfam PF00037 4Fe-4S binding domain 34 55 1.2E-6 T 11-11-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AUP74_RS10220 9857b24046764b80cd4192691c4b0a76 107 Pfam PF11953 Domain of unknown function (DUF3470) 66 107 2.0E-23 T 11-11-2016 IPR022569 Ferredoxin, C-terminal AUP74_RS00435 99333e91d120a94a1275414ce46e2dd1 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 50 203 7.1E-13 T 11-11-2016 AUP74_RS00435 99333e91d120a94a1275414ce46e2dd1 244 Gene3D G3DSA:3.40.50.720 7 244 6.3E-41 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS00435 99333e91d120a94a1275414ce46e2dd1 244 SUPERFAMILY SSF51735 7 244 3.15E-38 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS00435 99333e91d120a94a1275414ce46e2dd1 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.2E-5 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS00435 99333e91d120a94a1275414ce46e2dd1 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.2E-5 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS00435 99333e91d120a94a1275414ce46e2dd1 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 2.2E-5 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS11425 4cd2c01139ee6f4e66f4fbcf94dec37f 725 PRINTS PR00458 Haem peroxidase superfamily signature 132 149 2.3E-16 T 11-11-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AUP74_RS11425 4cd2c01139ee6f4e66f4fbcf94dec37f 725 PRINTS PR00458 Haem peroxidase superfamily signature 294 309 2.3E-16 T 11-11-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AUP74_RS11425 4cd2c01139ee6f4e66f4fbcf94dec37f 725 PRINTS PR00458 Haem peroxidase superfamily signature 235 250 2.3E-16 T 11-11-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AUP74_RS11425 4cd2c01139ee6f4e66f4fbcf94dec37f 725 PRINTS PR00458 Haem peroxidase superfamily signature 72 86 2.3E-16 T 11-11-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AUP74_RS11425 4cd2c01139ee6f4e66f4fbcf94dec37f 725 PRINTS PR00458 Haem peroxidase superfamily signature 150 162 2.3E-16 T 11-11-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AUP74_RS11425 4cd2c01139ee6f4e66f4fbcf94dec37f 725 Gene3D G3DSA:1.10.420.10 286 385 2.5E-43 T 11-11-2016 AUP74_RS11425 4cd2c01139ee6f4e66f4fbcf94dec37f 725 Gene3D G3DSA:1.10.420.10 228 250 2.5E-43 T 11-11-2016 AUP74_RS11425 4cd2c01139ee6f4e66f4fbcf94dec37f 725 Hamap MF_01961 Catalase-peroxidase [katG]. 2 715 40.919 T 11-11-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 AUP74_RS11425 4cd2c01139ee6f4e66f4fbcf94dec37f 725 SUPERFAMILY SSF48113 408 713 8.69E-111 T 11-11-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 AUP74_RS11425 4cd2c01139ee6f4e66f4fbcf94dec37f 725 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 235 245 - T 11-11-2016 IPR019793 Peroxidases heam-ligand binding site Reactome: R-HSA-2408557 AUP74_RS11425 4cd2c01139ee6f4e66f4fbcf94dec37f 725 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 458 484 2.3E-46 T 11-11-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 AUP74_RS11425 4cd2c01139ee6f4e66f4fbcf94dec37f 725 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 49 74 2.3E-46 T 11-11-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 AUP74_RS11425 4cd2c01139ee6f4e66f4fbcf94dec37f 725 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 34 47 2.3E-46 T 11-11-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 AUP74_RS11425 4cd2c01139ee6f4e66f4fbcf94dec37f 725 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 243 266 2.3E-46 T 11-11-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 AUP74_RS11425 4cd2c01139ee6f4e66f4fbcf94dec37f 725 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 8 30 2.3E-46 T 11-11-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 AUP74_RS11425 4cd2c01139ee6f4e66f4fbcf94dec37f 725 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 2 715 0.0 T 11-11-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 AUP74_RS11425 4cd2c01139ee6f4e66f4fbcf94dec37f 725 ProSitePatterns PS00436 Peroxidases active site signature. 72 83 - T 11-11-2016 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 AUP74_RS11425 4cd2c01139ee6f4e66f4fbcf94dec37f 725 Gene3D G3DSA:1.10.520.10 410 567 1.5E-63 T 11-11-2016 AUP74_RS11425 4cd2c01139ee6f4e66f4fbcf94dec37f 725 Gene3D G3DSA:1.10.520.10 693 714 1.5E-63 T 11-11-2016 AUP74_RS11425 4cd2c01139ee6f4e66f4fbcf94dec37f 725 Gene3D G3DSA:1.10.520.10 29 171 6.1E-69 T 11-11-2016 AUP74_RS11425 4cd2c01139ee6f4e66f4fbcf94dec37f 725 Gene3D G3DSA:1.10.520.10 203 227 6.1E-69 T 11-11-2016 AUP74_RS11425 4cd2c01139ee6f4e66f4fbcf94dec37f 725 Pfam PF00141 Peroxidase 381 688 4.5E-39 T 11-11-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AUP74_RS11425 4cd2c01139ee6f4e66f4fbcf94dec37f 725 Pfam PF00141 Peroxidase 58 374 1.2E-48 T 11-11-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AUP74_RS11425 4cd2c01139ee6f4e66f4fbcf94dec37f 725 SUPERFAMILY SSF48113 6 407 5.3E-144 T 11-11-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 AUP74_RS11425 4cd2c01139ee6f4e66f4fbcf94dec37f 725 Gene3D G3DSA:1.10.420.10 568 689 1.5E-46 T 11-11-2016 AUP74_RS10690 077b70feaaefdf31bce8340f4c15fef8 391 Pfam PF13437 HlyD family secretion protein 187 295 1.1E-7 T 11-11-2016 AUP74_RS10690 077b70feaaefdf31bce8340f4c15fef8 391 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 47 384 2.3E-47 T 11-11-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 AUP74_RS10690 077b70feaaefdf31bce8340f4c15fef8 391 Pfam PF13533 Biotin-lipoyl like 71 119 1.4E-6 T 11-11-2016 AUP74_RS10690 077b70feaaefdf31bce8340f4c15fef8 391 Gene3D G3DSA:2.40.50.100 70 104 1.6E-9 T 11-11-2016 AUP74_RS10690 077b70feaaefdf31bce8340f4c15fef8 391 Gene3D G3DSA:2.40.50.100 181 212 1.6E-9 T 11-11-2016 AUP74_RS10690 077b70feaaefdf31bce8340f4c15fef8 391 SUPERFAMILY SSF111369 58 291 2.35E-25 T 11-11-2016 AUP74_RS14930 5f50fe50f49ff2cbfe348e8121a435ce 446 Pfam PF00534 Glycosyl transferases group 1 249 401 9.0E-34 T 11-11-2016 IPR001296 Glycosyl transferase, family 1 AUP74_RS14930 5f50fe50f49ff2cbfe348e8121a435ce 446 Gene3D G3DSA:3.40.50.2000 214 400 3.4E-30 T 11-11-2016 AUP74_RS14930 5f50fe50f49ff2cbfe348e8121a435ce 446 Pfam PF13439 Glycosyltransferase Family 4 33 234 1.2E-27 T 11-11-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AUP74_RS14930 5f50fe50f49ff2cbfe348e8121a435ce 446 SUPERFAMILY SSF53756 21 424 2.22E-88 T 11-11-2016 AUP74_RS12810 6f672f91019b7133a8a5921704b7e7d4 239 SUPERFAMILY SSF55729 10 235 2.38E-92 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS12810 6f672f91019b7133a8a5921704b7e7d4 239 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 45 223 3.4E-67 T 11-11-2016 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 AUP74_RS12810 6f672f91019b7133a8a5921704b7e7d4 239 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 42 211 4.7E-74 T 11-11-2016 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 AUP74_RS12810 6f672f91019b7133a8a5921704b7e7d4 239 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 239 94.695 T 11-11-2016 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 AUP74_RS01025 659202e5ea4c3a6ba24e4b933c23816c 514 Pfam PF02638 Glycosyl hydrolase-like 10 54 366 6.0E-63 T 11-11-2016 IPR003790 Glycosyl hydrolase-like 10 AUP74_RS01025 659202e5ea4c3a6ba24e4b933c23816c 514 SUPERFAMILY SSF51445 84 358 4.83E-19 T 11-11-2016 IPR017853 Glycoside hydrolase superfamily AUP74_RS10080 457015c3569b0e328006859a34b96b3f 96 Hamap MF_00599 Cell division protein FtsB [ftsB]. 1 90 26.855 T 11-11-2016 IPR023081 Cell division protein FtsB AUP74_RS10080 457015c3569b0e328006859a34b96b3f 96 Pfam PF04977 Septum formation initiator 11 89 9.1E-19 T 11-11-2016 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 AUP74_RS07580 1c8c344a31da8259419d992726bf21f1 367 Gene3D G3DSA:3.20.20.190 30 355 1.2E-77 T 11-11-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 AUP74_RS07580 1c8c344a31da8259419d992726bf21f1 367 SUPERFAMILY SSF51695 31 355 3.4E-77 T 11-11-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 AUP74_RS07580 1c8c344a31da8259419d992726bf21f1 367 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 36 349 6.4E-55 T 11-11-2016 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 AUP74_RS13180 36d6c254e9246394d3513b2d5c4786bb 135 ProSitePatterns PS01314 Uncharacterized protein family UPF0047 signature. 98 116 - T 11-11-2016 IPR001602 Uncharacterised protein family UPF0047 AUP74_RS13180 36d6c254e9246394d3513b2d5c4786bb 135 PIRSF PIRSF004681 3 135 5.5E-48 T 11-11-2016 IPR001602 Uncharacterised protein family UPF0047 AUP74_RS13180 36d6c254e9246394d3513b2d5c4786bb 135 SUPERFAMILY SSF111038 10 134 1.57E-47 T 11-11-2016 IPR001602 Uncharacterised protein family UPF0047 AUP74_RS13180 36d6c254e9246394d3513b2d5c4786bb 135 Pfam PF01894 Uncharacterised protein family UPF0047 18 133 9.2E-39 T 11-11-2016 IPR001602 Uncharacterised protein family UPF0047 AUP74_RS13180 36d6c254e9246394d3513b2d5c4786bb 135 Gene3D G3DSA:2.60.120.460 5 134 6.7E-52 T 11-11-2016 IPR001602 Uncharacterised protein family UPF0047 AUP74_RS13180 36d6c254e9246394d3513b2d5c4786bb 135 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 11 134 1.0E-42 T 11-11-2016 IPR001602 Uncharacterised protein family UPF0047 AUP74_RS14015 4bf633351e83702d827b4f1e8be24028 326 SUPERFAMILY SSF55846 47 219 1.7E-39 T 11-11-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 AUP74_RS14015 4bf633351e83702d827b4f1e8be24028 326 SUPERFAMILY SSF47090 245 305 1.65E-14 T 11-11-2016 IPR002477 Peptidoglycan binding-like AUP74_RS14015 4bf633351e83702d827b4f1e8be24028 326 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 51 204 2.3E-17 T 11-11-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 AUP74_RS14015 4bf633351e83702d827b4f1e8be24028 326 SMART SM00644 41 203 1.6E-21 T 11-11-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 AUP74_RS14015 4bf633351e83702d827b4f1e8be24028 326 Gene3D G3DSA:3.40.80.10 43 222 3.8E-48 T 11-11-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 AUP74_RS16690 a26f5485dd46c4dd4045aede756021f2 134 Gene3D G3DSA:3.90.79.10 5 129 1.2E-37 T 11-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 AUP74_RS16690 a26f5485dd46c4dd4045aede756021f2 134 TIGRFAM TIGR00586 mutt: mutator mutT protein 2 128 5.4E-39 T 11-11-2016 IPR003561 Mutator MutT GO:0006281|GO:0008413 MetaCyc: PWY-6502 AUP74_RS16690 a26f5485dd46c4dd4045aede756021f2 134 SUPERFAMILY SSF55811 3 128 4.33E-39 T 11-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 AUP74_RS16690 a26f5485dd46c4dd4045aede756021f2 134 PRINTS PR00502 NUDIX hydrolase family signature 34 48 1.3E-7 T 11-11-2016 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AUP74_RS16690 a26f5485dd46c4dd4045aede756021f2 134 PRINTS PR00502 NUDIX hydrolase family signature 48 63 1.3E-7 T 11-11-2016 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AUP74_RS16690 a26f5485dd46c4dd4045aede756021f2 134 Pfam PF00293 NUDIX domain 6 118 1.3E-20 T 11-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 AUP74_RS04450 24366137d09e2119e9bf653485a3684f 462 Gene3D G3DSA:1.20.120.430 392 462 1.5E-56 T 11-11-2016 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 AUP74_RS04450 24366137d09e2119e9bf653485a3684f 462 Gene3D G3DSA:1.20.120.430 255 278 1.5E-56 T 11-11-2016 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 AUP74_RS04450 24366137d09e2119e9bf653485a3684f 462 Gene3D G3DSA:1.20.120.430 129 189 1.5E-56 T 11-11-2016 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 AUP74_RS04450 24366137d09e2119e9bf653485a3684f 462 Pfam PF10396 GTP-binding protein TrmE N-terminus 14 127 6.7E-38 T 11-11-2016 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 AUP74_RS04450 24366137d09e2119e9bf653485a3684f 462 Gene3D G3DSA:3.30.1360.120 9 128 3.9E-45 T 11-11-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 AUP74_RS04450 24366137d09e2119e9bf653485a3684f 462 SUPERFAMILY SSF116878 387 462 4.84E-48 T 11-11-2016 AUP74_RS04450 24366137d09e2119e9bf653485a3684f 462 SUPERFAMILY SSF116878 128 227 4.84E-48 T 11-11-2016 AUP74_RS04450 24366137d09e2119e9bf653485a3684f 462 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 224 378 8.8E-21 T 11-11-2016 IPR005225 Small GTP-binding protein domain GO:0005525 AUP74_RS04450 24366137d09e2119e9bf653485a3684f 462 SUPERFAMILY SSF52540 80 159 5.31E-45 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04450 24366137d09e2119e9bf653485a3684f 462 SUPERFAMILY SSF52540 195 380 5.31E-45 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04450 24366137d09e2119e9bf653485a3684f 462 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 19 462 1.4E-105 T 11-11-2016 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 AUP74_RS04450 24366137d09e2119e9bf653485a3684f 462 Pfam PF12631 MnmE helical domain 130 459 2.2E-58 T 11-11-2016 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 AUP74_RS04450 24366137d09e2119e9bf653485a3684f 462 Gene3D G3DSA:3.40.50.300 293 383 3.0E-10 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04450 24366137d09e2119e9bf653485a3684f 462 Gene3D G3DSA:3.40.50.300 218 254 2.6E-8 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04450 24366137d09e2119e9bf653485a3684f 462 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 13 462 32.74 T 11-11-2016 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 AUP74_RS04450 24366137d09e2119e9bf653485a3684f 462 Pfam PF01926 50S ribosome-binding GTPase 225 343 8.2E-24 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 AUP74_RS01255 960c7a7ee409667e028e9201d1e48dd3 465 Pfam PF05694 56kDa selenium binding protein (SBP56) 4 462 4.8E-198 T 11-11-2016 IPR008826 Selenium-binding protein GO:0008430 AUP74_RS01255 960c7a7ee409667e028e9201d1e48dd3 465 SUPERFAMILY SSF75011 38 402 2.48E-23 T 11-11-2016 AUP74_RS01255 960c7a7ee409667e028e9201d1e48dd3 465 Gene3D G3DSA:2.130.10.10 324 403 1.4E-9 T 11-11-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 AUP74_RS01255 960c7a7ee409667e028e9201d1e48dd3 465 Gene3D G3DSA:2.130.10.10 92 155 1.4E-9 T 11-11-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 AUP74_RS01255 960c7a7ee409667e028e9201d1e48dd3 465 Gene3D G3DSA:2.130.10.10 228 250 1.4E-9 T 11-11-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 AUP74_RS13950 85d037ed27c7da249448384622889d73 397 Pfam PF07075 Protein of unknown function (DUF1343) 52 394 3.1E-115 T 11-11-2016 IPR008302 Uncharacterised conserved protein UCP016719 AUP74_RS13950 85d037ed27c7da249448384622889d73 397 PIRSF PIRSF016719 2 395 2.5E-100 T 11-11-2016 IPR008302 Uncharacterised conserved protein UCP016719 AUP74_RS12845 53f90cac2223710b1d7dfe3edc237b76 198 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 8 175 4.3E-53 T 11-11-2016 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 AUP74_RS12845 53f90cac2223710b1d7dfe3edc237b76 198 Pfam PF00849 RNA pseudouridylate synthase 4 148 2.8E-16 T 11-11-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS12845 53f90cac2223710b1d7dfe3edc237b76 198 SUPERFAMILY SSF55120 4 178 4.64E-44 T 11-11-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS12845 53f90cac2223710b1d7dfe3edc237b76 198 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 39 53 - T 11-11-2016 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 AUP74_RS01490 2e2dd20bb13b82207a0367f6cab81a4b 301 Gene3D G3DSA:1.10.600.10 8 299 1.3E-89 T 11-11-2016 IPR008949 Isoprenoid synthase domain AUP74_RS01490 2e2dd20bb13b82207a0367f6cab81a4b 301 Pfam PF00348 Polyprenyl synthetase 38 271 1.4E-54 T 11-11-2016 IPR000092 Polyprenyl synthetase GO:0008299 AUP74_RS01490 2e2dd20bb13b82207a0367f6cab81a4b 301 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 220 232 - T 11-11-2016 IPR000092 Polyprenyl synthetase GO:0008299 AUP74_RS01490 2e2dd20bb13b82207a0367f6cab81a4b 301 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 90 106 - T 11-11-2016 IPR000092 Polyprenyl synthetase GO:0008299 AUP74_RS01490 2e2dd20bb13b82207a0367f6cab81a4b 301 SUPERFAMILY SSF48576 17 295 4.8E-81 T 11-11-2016 IPR008949 Isoprenoid synthase domain AUP74_RS05505 2c616615142bc1be67b4b770b0b4662c 270 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 95 1.3E-19 T 11-11-2016 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal AUP74_RS05505 2c616615142bc1be67b4b770b0b4662c 270 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 4 264 2.2E-71 T 11-11-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 AUP74_RS05505 2c616615142bc1be67b4b770b0b4662c 270 Gene3D G3DSA:3.40.50.720 2 157 5.8E-44 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS05505 2c616615142bc1be67b4b770b0b4662c 270 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 160 264 2.6E-31 T 11-11-2016 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 AUP74_RS05505 2c616615142bc1be67b4b770b0b4662c 270 PIRSF PIRSF000193 1 267 3.9E-71 T 11-11-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 AUP74_RS05505 2c616615142bc1be67b4b770b0b4662c 270 Gene3D G3DSA:1.10.3730.10 159 264 1.1E-32 T 11-11-2016 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 AUP74_RS05505 2c616615142bc1be67b4b770b0b4662c 270 SUPERFAMILY SSF51735 3 158 1.84E-36 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS05505 2c616615142bc1be67b4b770b0b4662c 270 SUPERFAMILY SSF48179 159 267 1.02E-31 T 11-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AUP74_RS05505 2c616615142bc1be67b4b770b0b4662c 270 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 1 264 23.767 T 11-11-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 AUP74_RS05760 dc411dcc85aa20763b4ca394418af92e 1482 SUPERFAMILY SSF56235 15 431 1.64E-142 T 11-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal AUP74_RS05760 dc411dcc85aa20763b4ca394418af92e 1482 SUPERFAMILY SSF51395 449 1189 1.79E-247 T 11-11-2016 AUP74_RS05760 dc411dcc85aa20763b4ca394418af92e 1482 Gene3D G3DSA:3.20.20.70 792 1191 3.2E-163 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS05760 dc411dcc85aa20763b4ca394418af92e 1482 Pfam PF00310 Glutamine amidotransferases class-II 15 428 5.1E-166 T 11-11-2016 IPR017932 Glutamine amidotransferase type 2 domain AUP74_RS05760 dc411dcc85aa20763b4ca394418af92e 1482 Gene3D G3DSA:2.160.20.60 1213 1467 7.5E-96 T 11-11-2016 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 AUP74_RS05760 dc411dcc85aa20763b4ca394418af92e 1482 SUPERFAMILY SSF69336 1214 1467 6.8E-91 T 11-11-2016 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 AUP74_RS05760 dc411dcc85aa20763b4ca394418af92e 1482 Gene3D G3DSA:3.60.20.10 15 436 1.1E-163 T 11-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal AUP74_RS05760 dc411dcc85aa20763b4ca394418af92e 1482 Pfam PF04898 Glutamate synthase central domain 458 737 1.7E-103 T 11-11-2016 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 AUP74_RS05760 dc411dcc85aa20763b4ca394418af92e 1482 Pfam PF01493 GXGXG motif 1237 1422 8.7E-79 T 11-11-2016 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 AUP74_RS05760 dc411dcc85aa20763b4ca394418af92e 1482 Gene3D G3DSA:3.20.20.70 448 776 1.3E-92 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS05760 dc411dcc85aa20763b4ca394418af92e 1482 Pfam PF01645 Conserved region in glutamate synthase 794 1157 8.7E-148 T 11-11-2016 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 AUP74_RS09005 66b0924bf6caa4ecfd8438fd93cb9617 475 Pfam PF00929 Exonuclease 8 187 2.3E-21 T 11-11-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III AUP74_RS09005 66b0924bf6caa4ecfd8438fd93cb9617 475 PIRSF PIRSF000977 1 473 1.7E-191 T 11-11-2016 IPR023607 Exodeoxyribonuclease I GO:0004529 AUP74_RS09005 66b0924bf6caa4ecfd8438fd93cb9617 475 Pfam PF08411 Exonuclease C-terminal 207 471 4.6E-89 T 11-11-2016 IPR013620 Exonuclease C-terminal GO:0006281|GO:0008852 AUP74_RS09005 66b0924bf6caa4ecfd8438fd93cb9617 475 Gene3D G3DSA:3.30.420.10 3 195 3.9E-76 T 11-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 AUP74_RS09005 66b0924bf6caa4ecfd8438fd93cb9617 475 SMART SM00479 5 198 0.0016 T 11-11-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III AUP74_RS09005 66b0924bf6caa4ecfd8438fd93cb9617 475 SUPERFAMILY SSF53098 5 459 9.87E-116 T 11-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 AUP74_RS11520 5380eba34e205f4e1c8f57d8d24b0537 871 ProSitePatterns PS01244 Aconitase family signature 2. 760 773 - T 11-11-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 AUP74_RS11520 5380eba34e205f4e1c8f57d8d24b0537 871 Gene3D G3DSA:3.30.499.10 683 857 1.7E-52 T 11-11-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS11520 5380eba34e205f4e1c8f57d8d24b0537 871 Gene3D G3DSA:3.40.1060.10 519 681 7.9E-87 T 11-11-2016 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS11520 5380eba34e205f4e1c8f57d8d24b0537 871 Gene3D G3DSA:3.20.19.10 162 359 3.0E-85 T 11-11-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel AUP74_RS11520 5380eba34e205f4e1c8f57d8d24b0537 871 Gene3D G3DSA:3.30.499.10 401 518 1.8E-62 T 11-11-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS11520 5380eba34e205f4e1c8f57d8d24b0537 871 SUPERFAMILY SSF74778 2 159 1.31E-67 T 11-11-2016 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 AUP74_RS11520 5380eba34e205f4e1c8f57d8d24b0537 871 Pfam PF06434 Aconitate hydratase 2 N-terminus 168 381 1.5E-93 T 11-11-2016 IPR015929 Aconitase B, N-terminal GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 AUP74_RS11520 5380eba34e205f4e1c8f57d8d24b0537 871 Pfam PF11791 Aconitate B N-terminal domain 4 156 4.9E-66 T 11-11-2016 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 AUP74_RS11520 5380eba34e205f4e1c8f57d8d24b0537 871 SUPERFAMILY SSF53732 377 855 1.31E-149 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS11520 5380eba34e205f4e1c8f57d8d24b0537 871 Pfam PF00330 Aconitase family (aconitate hydratase) 471 817 1.8E-39 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS11520 5380eba34e205f4e1c8f57d8d24b0537 871 TIGRFAM TIGR00117 acnB: aconitate hydratase 2 1 852 0.0 T 11-11-2016 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 AUP74_RS11520 5380eba34e205f4e1c8f57d8d24b0537 871 PIRSF PIRSF036687 1 858 0.0 T 11-11-2016 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 AUP74_RS11520 5380eba34e205f4e1c8f57d8d24b0537 871 SUPERFAMILY SSF52016 162 371 1.47E-67 T 11-11-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel AUP74_RS11520 5380eba34e205f4e1c8f57d8d24b0537 871 ProSitePatterns PS00450 Aconitase family signature 1. 701 718 - T 11-11-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 AUP74_RS08800 6c2795e5347cfdd79f0b2194c32ccb71 350 Pfam PF01757 Acyltransferase family 6 306 1.7E-30 T 11-11-2016 IPR002656 Acyltransferase 3 GO:0016747 AUP74_RS00840 3626b1c62380df19f5783cd8327fc42d 190 TIGRFAM TIGR03784 marine_sortase: sortase, marine proteobacterial type 6 179 5.8E-59 T 11-11-2016 IPR022445 Sortase, proteobacterial type AUP74_RS00840 3626b1c62380df19f5783cd8327fc42d 190 SUPERFAMILY SSF63817 47 181 9.42E-16 T 11-11-2016 IPR023365 Sortase domain AUP74_RS00840 3626b1c62380df19f5783cd8327fc42d 190 Pfam PF04203 Sortase family 67 180 2.2E-16 T 11-11-2016 IPR005754 Sortase family AUP74_RS00840 3626b1c62380df19f5783cd8327fc42d 190 TIGRFAM TIGR01076 sortase_fam: sortase 68 180 1.0E-10 T 11-11-2016 IPR005754 Sortase family AUP74_RS03080 77125d048f4d9b7c97faeb8f8e56e9d2 318 Hamap MF_00737 Formimidoylglutamase [hutG]. 5 313 40.738 T 11-11-2016 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 AUP74_RS03080 77125d048f4d9b7c97faeb8f8e56e9d2 318 Gene3D G3DSA:3.40.800.10 3 313 7.3E-101 T 11-11-2016 IPR023696 Ureohydrolase domain AUP74_RS03080 77125d048f4d9b7c97faeb8f8e56e9d2 318 Pfam PF00491 Arginase family 40 310 2.6E-58 T 11-11-2016 IPR006035 Ureohydrolase GO:0046872 AUP74_RS03080 77125d048f4d9b7c97faeb8f8e56e9d2 318 SUPERFAMILY SSF52768 9 311 1.58E-78 T 11-11-2016 AUP74_RS03080 77125d048f4d9b7c97faeb8f8e56e9d2 318 PRINTS PR00116 Arginase signature 239 268 3.9E-6 T 11-11-2016 IPR006035 Ureohydrolase GO:0046872 AUP74_RS03080 77125d048f4d9b7c97faeb8f8e56e9d2 318 PRINTS PR00116 Arginase signature 119 134 3.9E-6 T 11-11-2016 IPR006035 Ureohydrolase GO:0046872 AUP74_RS03080 77125d048f4d9b7c97faeb8f8e56e9d2 318 PRINTS PR00116 Arginase signature 274 288 3.9E-6 T 11-11-2016 IPR006035 Ureohydrolase GO:0046872 AUP74_RS03080 77125d048f4d9b7c97faeb8f8e56e9d2 318 TIGRFAM TIGR01227 hutG: formimidoylglutamase 10 308 2.2E-89 T 11-11-2016 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 AUP74_RS12530 39f69bd215a7b0114ff63f9675a1f9f5 197 Pfam PF02525 Flavodoxin-like fold 5 195 1.8E-44 T 11-11-2016 IPR003680 Flavodoxin-like fold AUP74_RS12530 39f69bd215a7b0114ff63f9675a1f9f5 197 Gene3D G3DSA:3.40.50.360 1 197 1.0E-65 T 11-11-2016 IPR029039 Flavoprotein-like domain AUP74_RS12530 39f69bd215a7b0114ff63f9675a1f9f5 197 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 197 30.31 T 11-11-2016 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 AUP74_RS12530 39f69bd215a7b0114ff63f9675a1f9f5 197 SUPERFAMILY SSF52218 2 196 2.58E-54 T 11-11-2016 IPR029039 Flavoprotein-like domain AUP74_RS12475 dad6af0546da93e4bf449f36e01a8078 1056 Gene3D G3DSA:3.30.70.1430 38 139 9.5E-35 T 11-11-2016 AUP74_RS12475 dad6af0546da93e4bf449f36e01a8078 1056 SUPERFAMILY SSF82866 296 497 6.02E-49 T 11-11-2016 AUP74_RS12475 dad6af0546da93e4bf449f36e01a8078 1056 SUPERFAMILY SSF82714 723 810 2.09E-22 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS12475 dad6af0546da93e4bf449f36e01a8078 1056 Gene3D G3DSA:3.30.70.1430 568 672 6.4E-36 T 11-11-2016 AUP74_RS12475 dad6af0546da93e4bf449f36e01a8078 1056 Gene3D G3DSA:1.10.3850.10 815 1028 2.0E-54 T 11-11-2016 AUP74_RS12475 dad6af0546da93e4bf449f36e01a8078 1056 Gene3D G3DSA:1.10.3850.10 278 498 2.3E-56 T 11-11-2016 AUP74_RS12475 dad6af0546da93e4bf449f36e01a8078 1056 Gene3D G3DSA:3.30.2090.10 722 810 9.5E-27 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS12475 dad6af0546da93e4bf449f36e01a8078 1056 SUPERFAMILY SSF82693 673 722 1.88E-29 T 11-11-2016 AUP74_RS12475 dad6af0546da93e4bf449f36e01a8078 1056 SUPERFAMILY SSF82693 809 857 1.88E-29 T 11-11-2016 AUP74_RS12475 dad6af0546da93e4bf449f36e01a8078 1056 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1044 0.0 T 11-11-2016 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 AUP74_RS12475 dad6af0546da93e4bf449f36e01a8078 1056 SUPERFAMILY SSF82693 566 672 3.4E-31 T 11-11-2016 AUP74_RS12475 dad6af0546da93e4bf449f36e01a8078 1056 Gene3D G3DSA:3.30.2090.10 181 275 2.0E-26 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS12475 dad6af0546da93e4bf449f36e01a8078 1056 SUPERFAMILY SSF82866 832 1026 2.22E-41 T 11-11-2016 AUP74_RS12475 dad6af0546da93e4bf449f36e01a8078 1056 SUPERFAMILY SSF82693 135 182 5.06E-27 T 11-11-2016 AUP74_RS12475 dad6af0546da93e4bf449f36e01a8078 1056 SUPERFAMILY SSF82693 274 330 5.06E-27 T 11-11-2016 AUP74_RS12475 dad6af0546da93e4bf449f36e01a8078 1056 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 1.5E-107 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS12475 dad6af0546da93e4bf449f36e01a8078 1056 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 1.5E-107 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS12475 dad6af0546da93e4bf449f36e01a8078 1056 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 1.5E-107 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS12475 dad6af0546da93e4bf449f36e01a8078 1056 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 1.5E-107 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS12475 dad6af0546da93e4bf449f36e01a8078 1056 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 1.5E-107 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS12475 dad6af0546da93e4bf449f36e01a8078 1056 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 1.5E-107 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS12475 dad6af0546da93e4bf449f36e01a8078 1056 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 1.5E-107 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS12475 dad6af0546da93e4bf449f36e01a8078 1056 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 1.5E-107 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS12475 dad6af0546da93e4bf449f36e01a8078 1056 PRINTS PR00702 Acriflavin resistance protein family signature 622 636 1.5E-107 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS12475 dad6af0546da93e4bf449f36e01a8078 1056 Pfam PF00873 AcrB/AcrD/AcrF family 1 1026 0.0 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS12475 dad6af0546da93e4bf449f36e01a8078 1056 SUPERFAMILY SSF82693 38 130 2.41E-26 T 11-11-2016 AUP74_RS12475 dad6af0546da93e4bf449f36e01a8078 1056 SUPERFAMILY SSF82714 182 272 1.09E-21 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS06590 74e59859848788b24695673f9442f5bf 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 161 180 1.1E-56 T 11-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AUP74_RS06590 74e59859848788b24695673f9442f5bf 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 199 218 1.1E-56 T 11-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AUP74_RS06590 74e59859848788b24695673f9442f5bf 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 278 293 1.1E-56 T 11-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AUP74_RS06590 74e59859848788b24695673f9442f5bf 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 308 327 1.1E-56 T 11-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AUP74_RS06590 74e59859848788b24695673f9442f5bf 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 130 144 1.1E-56 T 11-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AUP74_RS06590 74e59859848788b24695673f9442f5bf 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 253 269 1.1E-56 T 11-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AUP74_RS06590 74e59859848788b24695673f9442f5bf 336 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 253 265 - T 11-11-2016 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AUP74_RS06590 74e59859848788b24695673f9442f5bf 336 SUPERFAMILY SSF51569 8 335 1.99E-140 T 11-11-2016 AUP74_RS06590 74e59859848788b24695673f9442f5bf 336 SMART SM01004 10 334 3.5E-233 T 11-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AUP74_RS06590 74e59859848788b24695673f9442f5bf 336 PIRSF PIRSF001415 4 336 2.8E-146 T 11-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AUP74_RS06590 74e59859848788b24695673f9442f5bf 336 Gene3D G3DSA:3.20.20.70 9 335 9.1E-147 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS06590 74e59859848788b24695673f9442f5bf 336 Pfam PF00490 Delta-aminolevulinic acid dehydratase 13 332 6.7E-138 T 11-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AUP74_RS01820 a574218a015925fad5d0645f1395e5da 352 Pfam PF13533 Biotin-lipoyl like 43 92 1.6E-14 T 11-11-2016 AUP74_RS01820 a574218a015925fad5d0645f1395e5da 352 Gene3D G3DSA:2.40.50.100 43 77 3.0E-14 T 11-11-2016 AUP74_RS01820 a574218a015925fad5d0645f1395e5da 352 Gene3D G3DSA:2.40.50.100 200 230 3.0E-14 T 11-11-2016 AUP74_RS01820 a574218a015925fad5d0645f1395e5da 352 Pfam PF13437 HlyD family secretion protein 203 321 1.3E-11 T 11-11-2016 AUP74_RS01820 a574218a015925fad5d0645f1395e5da 352 SUPERFAMILY SSF111369 41 117 1.09E-13 T 11-11-2016 AUP74_RS01820 a574218a015925fad5d0645f1395e5da 352 SUPERFAMILY SSF111369 179 260 1.09E-13 T 11-11-2016 AUP74_RS08515 8d35891de10ee7a03b6b65bbb8660298 430 SUPERFAMILY SSF103473 20 414 5.75E-35 T 11-11-2016 IPR020846 Major facilitator superfamily domain AUP74_RS08515 8d35891de10ee7a03b6b65bbb8660298 430 Gene3D G3DSA:1.20.1250.20 24 237 2.1E-17 T 11-11-2016 AUP74_RS08515 8d35891de10ee7a03b6b65bbb8660298 430 Gene3D G3DSA:1.20.1250.20 243 412 1.1E-7 T 11-11-2016 AUP74_RS08515 8d35891de10ee7a03b6b65bbb8660298 430 Pfam PF07690 Major Facilitator Superfamily 30 370 4.8E-17 T 11-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AUP74_RS08515 8d35891de10ee7a03b6b65bbb8660298 430 TIGRFAM TIGR01272 gluP: glucose/galactose transporter WARNING 104 419 1.5E-105 T 11-11-2016 IPR005964 Bacterial glucose/galactose transporter GO:0005354|GO:0005355|GO:0009276|GO:0015757|GO:0015758|GO:0016021 AUP74_RS01760 62d3304d63c6e97f0b9941e9dd56cd09 179 SUPERFAMILY SSF109604 13 105 1.14E-12 T 11-11-2016 AUP74_RS01760 62d3304d63c6e97f0b9941e9dd56cd09 179 Gene3D G3DSA:1.10.3210.10 30 108 6.0E-5 T 11-11-2016 IPR006674 HD domain AUP74_RS10040 adacf1212b18f7bd859dcfc63a403691 318 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 6 148 3.8E-64 T 11-11-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 AUP74_RS10040 adacf1212b18f7bd859dcfc63a403691 318 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 5 316 48.662 T 11-11-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 AUP74_RS10040 adacf1212b18f7bd859dcfc63a403691 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 169 182 4.5E-42 T 11-11-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 AUP74_RS10040 adacf1212b18f7bd859dcfc63a403691 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 197 206 4.5E-42 T 11-11-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 AUP74_RS10040 adacf1212b18f7bd859dcfc63a403691 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 153 166 4.5E-42 T 11-11-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 AUP74_RS10040 adacf1212b18f7bd859dcfc63a403691 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 134 150 4.5E-42 T 11-11-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 AUP74_RS10040 adacf1212b18f7bd859dcfc63a403691 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 88 99 4.5E-42 T 11-11-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 AUP74_RS10040 adacf1212b18f7bd859dcfc63a403691 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 113 131 4.5E-42 T 11-11-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 AUP74_RS10040 adacf1212b18f7bd859dcfc63a403691 318 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 2 316 1.5E-147 T 11-11-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 AUP74_RS10040 adacf1212b18f7bd859dcfc63a403691 318 SUPERFAMILY SSF52096 5 314 6.43E-101 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS10040 adacf1212b18f7bd859dcfc63a403691 318 Gene3D G3DSA:3.90.226.10 55 272 1.2E-47 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS15805 52a3137242be48f6295cd0f9884d2efe 495 Gene3D G3DSA:3.20.20.70 8 490 9.1E-199 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS15805 52a3137242be48f6295cd0f9884d2efe 495 SUPERFAMILY SSF54631 99 206 7.56E-25 T 11-11-2016 AUP74_RS15805 52a3137242be48f6295cd0f9884d2efe 495 Pfam PF00571 CBS domain 99 143 7.8E-9 T 11-11-2016 IPR000644 CBS domain AUP74_RS15805 52a3137242be48f6295cd0f9884d2efe 495 SMART SM01240 11 479 0.0 T 11-11-2016 AUP74_RS15805 52a3137242be48f6295cd0f9884d2efe 495 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 12 492 82.942 T 11-11-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 AUP74_RS15805 52a3137242be48f6295cd0f9884d2efe 495 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 298 310 - T 11-11-2016 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 AUP74_RS15805 52a3137242be48f6295cd0f9884d2efe 495 SUPERFAMILY SSF51412 7 94 1.02E-126 T 11-11-2016 AUP74_RS15805 52a3137242be48f6295cd0f9884d2efe 495 SUPERFAMILY SSF51412 220 483 1.02E-126 T 11-11-2016 AUP74_RS15805 52a3137242be48f6295cd0f9884d2efe 495 SMART SM00116 161 209 2.2E-5 T 11-11-2016 IPR000644 CBS domain AUP74_RS15805 52a3137242be48f6295cd0f9884d2efe 495 SMART SM00116 100 147 1.8E-8 T 11-11-2016 IPR000644 CBS domain AUP74_RS15805 52a3137242be48f6295cd0f9884d2efe 495 PIRSF PIRSF000130 1 493 4.9E-204 T 11-11-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 AUP74_RS15805 52a3137242be48f6295cd0f9884d2efe 495 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 12 479 2.8E-162 T 11-11-2016 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 AUP74_RS15805 52a3137242be48f6295cd0f9884d2efe 495 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 12 460 2.1E-186 T 11-11-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 AUP74_RS11690 d640e51125e5deaab178b78ae7d6c8cb 121 Pfam PF09722 Protein of unknown function (DUF2384) 72 119 9.6E-12 T 11-11-2016 IPR024467 Domain of unknown function DUF2384 AUP74_RS05870 8857666544cd4bb4362f21f6051dd3c9 338 Gene3D G3DSA:3.40.630.10 33 227 2.9E-24 T 11-11-2016 AUP74_RS05870 8857666544cd4bb4362f21f6051dd3c9 338 SUPERFAMILY SSF53187 20 315 4.3E-74 T 11-11-2016 AUP74_RS05870 8857666544cd4bb4362f21f6051dd3c9 338 PIRSF PIRSF039012 1 320 3.0E-89 T 11-11-2016 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 AUP74_RS05870 8857666544cd4bb4362f21f6051dd3c9 338 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 45 313 4.3E-59 T 11-11-2016 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 AUP74_RS05735 d5cbd3230a0cb5b217b52d6f0bd7ba7e 206 Gene3D G3DSA:3.30.70.60 103 205 1.4E-35 T 11-11-2016 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 AUP74_RS05735 d5cbd3230a0cb5b217b52d6f0bd7ba7e 206 Gene3D G3DSA:1.10.287.540 68 102 1.9E-17 T 11-11-2016 IPR023218 UPF0291 structural domain AUP74_RS05735 d5cbd3230a0cb5b217b52d6f0bd7ba7e 206 PIRSF PIRSF016482 4 205 1.5E-60 T 11-11-2016 IPR007445 Pilus assembly protein, PilO AUP74_RS05735 d5cbd3230a0cb5b217b52d6f0bd7ba7e 206 Pfam PF04350 Pilus assembly protein, PilO 59 201 2.2E-52 T 11-11-2016 IPR007445 Pilus assembly protein, PilO AUP74_RS03305 ba341e812b8d56d4e74abf6ce112b782 320 Gene3D G3DSA:1.10.443.10 130 258 6.2E-7 T 11-11-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 AUP74_RS03305 ba341e812b8d56d4e74abf6ce112b782 320 Pfam PF12835 Integrase 133 257 3.6E-6 T 11-11-2016 IPR024456 Integrase catalytic domain, putative AUP74_RS03305 ba341e812b8d56d4e74abf6ce112b782 320 SUPERFAMILY SSF56349 26 263 4.41E-12 T 11-11-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AUP74_RS03305 ba341e812b8d56d4e74abf6ce112b782 320 Gene3D G3DSA:1.10.150.130 32 94 2.5E-4 T 11-11-2016 IPR023109 Integrase/recombinase, N-terminal AUP74_RS10615 fa939ac93d1868d4ea3f8dd32b86b38e 310 SUPERFAMILY SSF52540 4 229 2.27E-63 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS10615 fa939ac93d1868d4ea3f8dd32b86b38e 310 Gene3D G3DSA:3.40.50.300 2 226 1.1E-68 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS10615 fa939ac93d1868d4ea3f8dd32b86b38e 310 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AUP74_RS10615 fa939ac93d1868d4ea3f8dd32b86b38e 310 Pfam PF00005 ABC transporter 21 165 6.0E-31 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AUP74_RS10615 fa939ac93d1868d4ea3f8dd32b86b38e 310 SMART SM00382 30 213 3.8E-13 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS13630 8f49297f400e086232e5fa55dc1e8517 502 Pfam PF14707 C-terminal region of aryl-sulfatase 384 479 3.1E-7 T 11-11-2016 AUP74_RS13630 8f49297f400e086232e5fa55dc1e8517 502 Gene3D G3DSA:3.40.720.10 12 395 1.2E-92 T 11-11-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 AUP74_RS13630 8f49297f400e086232e5fa55dc1e8517 502 SUPERFAMILY SSF53649 10 487 4.8E-117 T 11-11-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 AUP74_RS13630 8f49297f400e086232e5fa55dc1e8517 502 Pfam PF00884 Sulfatase 14 341 1.2E-58 T 11-11-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 AUP74_RS13630 8f49297f400e086232e5fa55dc1e8517 502 Gene3D G3DSA:3.30.1120.10 396 455 2.8E-9 T 11-11-2016 AUP74_RS11140 ff277d78c436eced487f893a1b74ba0c 451 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 318 1.4E-69 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS11140 ff277d78c436eced487f893a1b74ba0c 451 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 338 446 5.4E-37 T 11-11-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AUP74_RS11140 ff277d78c436eced487f893a1b74ba0c 451 SUPERFAMILY SSF55424 335 448 2.92E-38 T 11-11-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 AUP74_RS11140 ff277d78c436eced487f893a1b74ba0c 451 Gene3D G3DSA:3.50.50.60 5 135 1.8E-39 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS11140 ff277d78c436eced487f893a1b74ba0c 451 SUPERFAMILY SSF51905 5 359 2.05E-57 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS11140 ff277d78c436eced487f893a1b74ba0c 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 6.8E-70 T 11-11-2016 AUP74_RS11140 ff277d78c436eced487f893a1b74ba0c 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 421 441 6.8E-70 T 11-11-2016 AUP74_RS11140 ff277d78c436eced487f893a1b74ba0c 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 255 269 6.8E-70 T 11-11-2016 AUP74_RS11140 ff277d78c436eced487f893a1b74ba0c 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 6.8E-70 T 11-11-2016 AUP74_RS11140 ff277d78c436eced487f893a1b74ba0c 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 334 355 6.8E-70 T 11-11-2016 AUP74_RS11140 ff277d78c436eced487f893a1b74ba0c 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 399 414 6.8E-70 T 11-11-2016 AUP74_RS11140 ff277d78c436eced487f893a1b74ba0c 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 298 305 6.8E-70 T 11-11-2016 AUP74_RS11140 ff277d78c436eced487f893a1b74ba0c 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 135 144 6.8E-70 T 11-11-2016 AUP74_RS11140 ff277d78c436eced487f893a1b74ba0c 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 169 194 6.8E-70 T 11-11-2016 AUP74_RS11140 ff277d78c436eced487f893a1b74ba0c 451 Gene3D G3DSA:3.30.390.30 337 450 8.0E-47 T 11-11-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AUP74_RS11140 ff277d78c436eced487f893a1b74ba0c 451 PIRSF PIRSF000350 2 443 2.2E-85 T 11-11-2016 AUP74_RS11140 ff277d78c436eced487f893a1b74ba0c 451 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 270 5.4E-30 T 11-11-2016 AUP74_RS11140 ff277d78c436eced487f893a1b74ba0c 451 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 5.4E-30 T 11-11-2016 AUP74_RS11140 ff277d78c436eced487f893a1b74ba0c 451 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 150 5.4E-30 T 11-11-2016 AUP74_RS11140 ff277d78c436eced487f893a1b74ba0c 451 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 283 305 5.4E-30 T 11-11-2016 AUP74_RS11140 ff277d78c436eced487f893a1b74ba0c 451 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 5.4E-30 T 11-11-2016 AUP74_RS11140 ff277d78c436eced487f893a1b74ba0c 451 Gene3D G3DSA:3.50.50.60 136 324 3.5E-53 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS11140 ff277d78c436eced487f893a1b74ba0c 451 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 40 50 - T 11-11-2016 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 AUP74_RS03000 eb12b3895564aed10fa7b2f0e65e815b 277 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 7 274 2.5E-95 T 11-11-2016 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 AUP74_RS03000 eb12b3895564aed10fa7b2f0e65e815b 277 Pfam PF02219 Methylenetetrahydrofolate reductase 3 274 1.4E-80 T 11-11-2016 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 AUP74_RS03000 eb12b3895564aed10fa7b2f0e65e815b 277 Gene3D G3DSA:3.20.20.220 3 276 1.5E-99 T 11-11-2016 IPR029041 FAD-linked oxidoreductase-like AUP74_RS03000 eb12b3895564aed10fa7b2f0e65e815b 277 SUPERFAMILY SSF51730 3 275 2.16E-93 T 11-11-2016 IPR029041 FAD-linked oxidoreductase-like AUP74_RS11785 a5b747588b19e7fb71ceaf50e42c54c6 345 Gene3D G3DSA:3.20.20.70 1 336 6.0E-128 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS11785 a5b747588b19e7fb71ceaf50e42c54c6 345 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 79 98 - T 11-11-2016 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 AUP74_RS11785 a5b747588b19e7fb71ceaf50e42c54c6 345 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 1 335 50.405 T 11-11-2016 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 AUP74_RS11785 a5b747588b19e7fb71ceaf50e42c54c6 345 PIRSF PIRSF000164 19 344 8.9E-99 T 11-11-2016 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 AUP74_RS11785 a5b747588b19e7fb71ceaf50e42c54c6 345 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 2 336 1.3E-132 T 11-11-2016 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 AUP74_RS11785 a5b747588b19e7fb71ceaf50e42c54c6 345 SUPERFAMILY SSF51395 1 336 5.0E-105 T 11-11-2016 AUP74_RS11785 a5b747588b19e7fb71ceaf50e42c54c6 345 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 291 311 - T 11-11-2016 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 AUP74_RS11785 a5b747588b19e7fb71ceaf50e42c54c6 345 Pfam PF01180 Dihydroorotate dehydrogenase 46 333 1.2E-88 T 11-11-2016 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 AUP74_RS16795 dfc0bcae0bf895851e2244b8c297c3bb 280 SUPERFAMILY SSF53790 6 225 5.5E-80 T 11-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 AUP74_RS16795 dfc0bcae0bf895851e2244b8c297c3bb 280 Gene3D G3DSA:3.30.950.10 115 228 3.0E-43 T 11-11-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 AUP74_RS16795 dfc0bcae0bf895851e2244b8c297c3bb 280 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 7 207 7.4E-31 T 11-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 AUP74_RS16795 dfc0bcae0bf895851e2244b8c297c3bb 280 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 84 95 - T 11-11-2016 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AUP74_RS16795 dfc0bcae0bf895851e2244b8c297c3bb 280 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 6 227 37.558 T 11-11-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AUP74_RS16795 dfc0bcae0bf895851e2244b8c297c3bb 280 PIRSF PIRSF005917 1 280 4.5E-103 T 11-11-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AUP74_RS16795 dfc0bcae0bf895851e2244b8c297c3bb 280 Gene3D G3DSA:3.40.1010.10 6 114 1.8E-13 T 11-11-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 AUP74_RS16795 dfc0bcae0bf895851e2244b8c297c3bb 280 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 6 277 1.0E-91 T 11-11-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AUP74_RS01140 049b14adc2e247d2024dea7c45d18518 257 SMART SM01007 24 204 1.3E-64 T 11-11-2016 IPR001303 Class II aldolase/adducin N-terminal AUP74_RS01140 049b14adc2e247d2024dea7c45d18518 257 Gene3D G3DSA:3.40.225.10 19 227 5.5E-62 T 11-11-2016 IPR001303 Class II aldolase/adducin N-terminal AUP74_RS01140 049b14adc2e247d2024dea7c45d18518 257 SUPERFAMILY SSF53639 18 224 2.75E-60 T 11-11-2016 IPR001303 Class II aldolase/adducin N-terminal AUP74_RS01140 049b14adc2e247d2024dea7c45d18518 257 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 25 204 2.2E-44 T 11-11-2016 IPR001303 Class II aldolase/adducin N-terminal AUP74_RS02240 ad24082df4d5f3962d5631d31f221d51 446 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 421 4.3E-139 T 11-11-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AUP74_RS02240 ad24082df4d5f3962d5631d31f221d51 446 SMART SM00984 321 425 1.1E-52 T 11-11-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AUP74_RS02240 ad24082df4d5f3962d5631d31f221d51 446 Gene3D G3DSA:3.40.50.720 236 442 7.4E-76 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS02240 ad24082df4d5f3962d5631d31f221d51 446 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 187 7.4E-65 T 11-11-2016 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AUP74_RS02240 ad24082df4d5f3962d5631d31f221d51 446 SUPERFAMILY SSF52413 306 436 6.15E-42 T 11-11-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AUP74_RS02240 ad24082df4d5f3962d5631d31f221d51 446 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 321 424 5.1E-31 T 11-11-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AUP74_RS02240 ad24082df4d5f3962d5631d31f221d51 446 PIRSF PIRSF000124 1 440 3.0E-150 T 11-11-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AUP74_RS02240 ad24082df4d5f3962d5631d31f221d51 446 Gene3D G3DSA:1.20.5.100 208 235 6.2E-18 T 11-11-2016 AUP74_RS02240 ad24082df4d5f3962d5631d31f221d51 446 PIRSF PIRSF500134 1 443 7.9E-190 T 11-11-2016 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00500+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346 AUP74_RS02240 ad24082df4d5f3962d5631d31f221d51 446 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 205 297 2.4E-37 T 11-11-2016 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AUP74_RS02240 ad24082df4d5f3962d5631d31f221d51 446 SUPERFAMILY SSF48179 205 303 1.22E-32 T 11-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AUP74_RS02240 ad24082df4d5f3962d5631d31f221d51 446 SUPERFAMILY SSF51735 1 196 1.9E-52 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS02240 ad24082df4d5f3962d5631d31f221d51 446 Gene3D G3DSA:3.40.50.720 1 207 4.1E-76 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS12355 5241285742dd1fc58d7c5f4f20dc9220 336 PIRSF PIRSF002786 7 315 2.2E-62 T 11-11-2016 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 AUP74_RS12355 5241285742dd1fc58d7c5f4f20dc9220 336 Gene3D G3DSA:3.30.1300.30 271 311 2.5E-6 T 11-11-2016 AUP74_RS12355 5241285742dd1fc58d7c5f4f20dc9220 336 Gene3D G3DSA:3.30.1300.30 36 110 2.5E-6 T 11-11-2016 AUP74_RS12355 5241285742dd1fc58d7c5f4f20dc9220 336 SUPERFAMILY SSF158544 113 214 6.02E-23 T 11-11-2016 AUP74_RS12355 5241285742dd1fc58d7c5f4f20dc9220 336 Gene3D G3DSA:1.10.40.60 112 214 8.3E-26 T 11-11-2016 AUP74_RS12355 5241285742dd1fc58d7c5f4f20dc9220 336 SUPERFAMILY SSF54523 44 112 2.04E-8 T 11-11-2016 AUP74_RS12355 5241285742dd1fc58d7c5f4f20dc9220 336 SUPERFAMILY SSF54523 270 311 2.04E-8 T 11-11-2016 AUP74_RS12355 5241285742dd1fc58d7c5f4f20dc9220 336 Pfam PF03934 Type II secretion system (T2SS), protein K 37 300 4.9E-58 T 11-11-2016 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 AUP74_RS15445 cb3a03e8d8e034ec073f55c3034486be 240 Gene3D G3DSA:3.40.470.10 5 227 5.2E-103 T 11-11-2016 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AUP74_RS15445 cb3a03e8d8e034ec073f55c3034486be 240 SMART SM00986 55 215 1.6E-39 T 11-11-2016 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AUP74_RS15445 cb3a03e8d8e034ec073f55c3034486be 240 SUPERFAMILY SSF52141 7 226 1.31E-94 T 11-11-2016 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AUP74_RS15445 cb3a03e8d8e034ec073f55c3034486be 240 SMART SM00987 55 215 1.6E-39 T 11-11-2016 AUP74_RS15445 cb3a03e8d8e034ec073f55c3034486be 240 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 63 72 - T 11-11-2016 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AUP74_RS15445 cb3a03e8d8e034ec073f55c3034486be 240 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 11 219 1.0E-82 T 11-11-2016 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AUP74_RS15445 cb3a03e8d8e034ec073f55c3034486be 240 Pfam PF03167 Uracil DNA glycosylase superfamily 60 215 6.9E-23 T 11-11-2016 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AUP74_RS15445 cb3a03e8d8e034ec073f55c3034486be 240 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 10 226 40.828 T 11-11-2016 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AUP74_RS05400 f2460628334101b4dcc6e02547ca8c00 498 Gene3D G3DSA:3.40.50.300 189 381 8.6E-50 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05400 f2460628334101b4dcc6e02547ca8c00 498 Gene3D G3DSA:3.30.230.10 10 150 5.4E-26 T 11-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AUP74_RS05400 f2460628334101b4dcc6e02547ca8c00 498 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 395 487 2.2E-29 T 11-11-2016 IPR025158 Mg chelatase-related protein, C-terminal domain AUP74_RS05400 f2460628334101b4dcc6e02547ca8c00 498 SMART SM00382 209 385 1.4E-9 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS05400 f2460628334101b4dcc6e02547ca8c00 498 SUPERFAMILY SSF52540 189 491 3.84E-45 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05400 f2460628334101b4dcc6e02547ca8c00 498 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 141 2.9E-45 T 11-11-2016 AUP74_RS05400 f2460628334101b4dcc6e02547ca8c00 498 Pfam PF01078 Magnesium chelatase, subunit ChlI 189 388 3.1E-93 T 11-11-2016 IPR000523 Magnesium chelatase ChlI domain AUP74_RS05400 f2460628334101b4dcc6e02547ca8c00 498 SUPERFAMILY SSF54211 7 166 2.5E-29 T 11-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold AUP74_RS05400 f2460628334101b4dcc6e02547ca8c00 498 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 7 487 2.3E-187 T 11-11-2016 IPR004482 Mg chelatase-related protein AUP74_RS08960 fa73795b3231cb0220d2799607584309 215 Pfam PF00313 'Cold-shock' DNA-binding domain 4 62 4.3E-9 T 11-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AUP74_RS08960 fa73795b3231cb0220d2799607584309 215 SMART SM00357 4 68 1.6E-4 T 11-11-2016 IPR011129 Cold shock protein GO:0003676 AUP74_RS08960 fa73795b3231cb0220d2799607584309 215 Gene3D G3DSA:2.40.50.140 4 69 1.0E-17 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS08960 fa73795b3231cb0220d2799607584309 215 SUPERFAMILY SSF50249 3 69 1.79E-12 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS08960 fa73795b3231cb0220d2799607584309 215 ProSitePatterns PS00352 'Cold-shock' domain signature. 16 35 - T 11-11-2016 IPR019844 Cold-shock conserved site AUP74_RS08960 fa73795b3231cb0220d2799607584309 215 Pfam PF06961 Protein of unknown function (DUF1294) 116 170 1.9E-22 T 11-11-2016 IPR010718 Protein of unknown function DUF1294 AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 Gene3D G3DSA:2.40.50.140 21 100 2.6E-13 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 Gene3D G3DSA:2.40.50.140 280 357 1.1E-29 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 Gene3D G3DSA:2.40.50.140 192 279 1.9E-30 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 SUPERFAMILY SSF50249 105 184 5.58E-14 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 3 520 2.6E-212 T 11-11-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 SUPERFAMILY SSF50249 189 277 8.95E-27 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 PIRSF PIRSF002111 1 534 8.4E-217 T 11-11-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 SUPERFAMILY SSF50249 429 534 7.15E-22 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 Gene3D G3DSA:2.40.50.140 101 172 2.0E-13 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 Gene3D G3DSA:2.40.50.140 445 521 1.2E-20 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 SUPERFAMILY SSF50249 1 112 1.72E-20 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 SMART SM00316 449 520 1.6E-17 T 11-11-2016 IPR022967 RNA-binding domain, S1 AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 SMART SM00316 190 260 1.4E-27 T 11-11-2016 IPR022967 RNA-binding domain, S1 AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 SMART SM00316 103 171 1.1E-7 T 11-11-2016 IPR022967 RNA-binding domain, S1 AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 SMART SM00316 19 87 1.3E-8 T 11-11-2016 IPR022967 RNA-binding domain, S1 AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 SMART SM00316 275 347 1.2E-25 T 11-11-2016 IPR022967 RNA-binding domain, S1 AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 SMART SM00316 362 434 9.4E-19 T 11-11-2016 IPR022967 RNA-binding domain, S1 AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 Gene3D G3DSA:2.40.50.140 358 439 6.8E-25 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 Pfam PF00575 S1 RNA binding domain 102 171 3.5E-11 T 11-11-2016 IPR003029 S1 domain GO:0003676 AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 Pfam PF00575 S1 RNA binding domain 451 520 1.7E-12 T 11-11-2016 IPR003029 S1 domain GO:0003676 AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 Pfam PF00575 S1 RNA binding domain 275 347 8.0E-21 T 11-11-2016 IPR003029 S1 domain GO:0003676 AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 Pfam PF00575 S1 RNA binding domain 19 85 7.8E-9 T 11-11-2016 IPR003029 S1 domain GO:0003676 AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 Pfam PF00575 S1 RNA binding domain 189 260 7.6E-21 T 11-11-2016 IPR003029 S1 domain GO:0003676 AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 Pfam PF00575 S1 RNA binding domain 360 434 7.6E-19 T 11-11-2016 IPR003029 S1 domain GO:0003676 AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 SUPERFAMILY SSF50249 255 361 3.13E-27 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 PRINTS PR00681 Ribosomal protein S1 signature 290 309 1.2E-87 T 11-11-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 PRINTS PR00681 Ribosomal protein S1 signature 126 143 1.2E-87 T 11-11-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 PRINTS PR00681 Ribosomal protein S1 signature 21 39 1.2E-87 T 11-11-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 PRINTS PR00681 Ribosomal protein S1 signature 84 103 1.2E-87 T 11-11-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 PRINTS PR00681 Ribosomal protein S1 signature 155 175 1.2E-87 T 11-11-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 PRINTS PR00681 Ribosomal protein S1 signature 108 124 1.2E-87 T 11-11-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 PRINTS PR00681 Ribosomal protein S1 signature 39 53 1.2E-87 T 11-11-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 PRINTS PR00681 Ribosomal protein S1 signature 330 348 1.2E-87 T 11-11-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 PRINTS PR00681 Ribosomal protein S1 signature 212 233 1.2E-87 T 11-11-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 AUP74_RS14795 56a587f42fbea8827a747c1308ec41e6 559 SUPERFAMILY SSF50249 347 439 1.27E-20 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS15345 d7dbdac0029e940f9f4861ff12c13b1a 946 SUPERFAMILY SSF55874 352 524 3.92E-28 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS15345 d7dbdac0029e940f9f4861ff12c13b1a 946 Pfam PF01627 Hpt domain 839 925 3.4E-7 T 11-11-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 AUP74_RS15345 d7dbdac0029e940f9f4861ff12c13b1a 946 PRINTS PR00344 Bacterial sensor protein C-terminal signature 486 504 5.9E-6 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS15345 d7dbdac0029e940f9f4861ff12c13b1a 946 PRINTS PR00344 Bacterial sensor protein C-terminal signature 510 523 5.9E-6 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS15345 d7dbdac0029e940f9f4861ff12c13b1a 946 SMART SM00304 206 258 0.0045 T 11-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 AUP74_RS15345 d7dbdac0029e940f9f4861ff12c13b1a 946 SMART SM00448 541 659 0.21 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS15345 d7dbdac0029e940f9f4861ff12c13b1a 946 SMART SM00448 684 797 8.3E-42 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS15345 d7dbdac0029e940f9f4861ff12c13b1a 946 Pfam PF00672 HAMP domain 187 254 1.7E-7 T 11-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 AUP74_RS15345 d7dbdac0029e940f9f4861ff12c13b1a 946 SUPERFAMILY SSF52172 539 670 2.7E-13 T 11-11-2016 IPR011006 CheY-like superfamily AUP74_RS15345 d7dbdac0029e940f9f4861ff12c13b1a 946 Pfam PF00512 His Kinase A (phospho-acceptor) domain 299 363 4.4E-19 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS15345 d7dbdac0029e940f9f4861ff12c13b1a 946 SMART SM00073 828 926 4.3E-4 T 11-11-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 AUP74_RS15345 d7dbdac0029e940f9f4861ff12c13b1a 946 Gene3D G3DSA:1.20.120.160 830 926 3.9E-12 T 11-11-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 AUP74_RS15345 d7dbdac0029e940f9f4861ff12c13b1a 946 SUPERFAMILY SSF47384 284 364 1.61E-22 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS15345 d7dbdac0029e940f9f4861ff12c13b1a 946 SMART SM00388 298 363 1.3E-24 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS15345 d7dbdac0029e940f9f4861ff12c13b1a 946 Gene3D G3DSA:1.10.287.130 291 348 1.8E-17 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS15345 d7dbdac0029e940f9f4861ff12c13b1a 946 SUPERFAMILY SSF52172 684 819 4.27E-42 T 11-11-2016 IPR011006 CheY-like superfamily AUP74_RS15345 d7dbdac0029e940f9f4861ff12c13b1a 946 SMART SM00387 410 526 1.5E-12 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS15345 d7dbdac0029e940f9f4861ff12c13b1a 946 Pfam PF00072 Response regulator receiver domain 686 797 1.5E-30 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS15345 d7dbdac0029e940f9f4861ff12c13b1a 946 Gene3D G3DSA:3.40.50.2300 683 809 1.5E-43 T 11-11-2016 AUP74_RS15345 d7dbdac0029e940f9f4861ff12c13b1a 946 Gene3D G3DSA:3.30.565.10 349 524 5.6E-28 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS15345 d7dbdac0029e940f9f4861ff12c13b1a 946 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 410 524 3.9E-14 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS15345 d7dbdac0029e940f9f4861ff12c13b1a 946 Gene3D G3DSA:3.40.50.2300 539 671 1.9E-10 T 11-11-2016 AUP74_RS15345 d7dbdac0029e940f9f4861ff12c13b1a 946 SUPERFAMILY SSF47226 780 901 6.67E-16 T 11-11-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 AUP74_RS09175 192b3da6f30c8eb9e8138b970e2f3ba3 389 TIGRFAM TIGR03300 assembly_YfgL: outer membrane assembly lipoprotein YfgL 10 383 6.3E-130 T 11-11-2016 IPR017687 Outer membrane protein assembly factor BamB AUP74_RS09175 192b3da6f30c8eb9e8138b970e2f3ba3 389 Hamap MF_00923 Outer membrane protein assembly factor BamB [bamB]. 5 385 37.217 T 11-11-2016 IPR017687 Outer membrane protein assembly factor BamB AUP74_RS09175 192b3da6f30c8eb9e8138b970e2f3ba3 389 Gene3D G3DSA:2.140.10.10 10 385 8.5E-80 T 11-11-2016 IPR027295 Quinoprotein alcohol dehydrogenase-like domain AUP74_RS09175 192b3da6f30c8eb9e8138b970e2f3ba3 389 Pfam PF13360 PQQ-like domain 81 311 2.2E-56 T 11-11-2016 IPR002372 Pyrrolo-quinoline quinone repeat AUP74_RS09175 192b3da6f30c8eb9e8138b970e2f3ba3 389 SMART SM00564 323 354 0.27 T 11-11-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AUP74_RS09175 192b3da6f30c8eb9e8138b970e2f3ba3 389 SMART SM00564 193 224 0.0018 T 11-11-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AUP74_RS09175 192b3da6f30c8eb9e8138b970e2f3ba3 389 SMART SM00564 68 99 4.7E-4 T 11-11-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AUP74_RS09175 192b3da6f30c8eb9e8138b970e2f3ba3 389 SMART SM00564 148 179 0.41 T 11-11-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AUP74_RS09175 192b3da6f30c8eb9e8138b970e2f3ba3 389 SMART SM00564 244 275 7.2E-5 T 11-11-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AUP74_RS09175 192b3da6f30c8eb9e8138b970e2f3ba3 389 SMART SM00564 281 313 0.0078 T 11-11-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AUP74_RS09175 192b3da6f30c8eb9e8138b970e2f3ba3 389 SMART SM00564 107 139 1.1 T 11-11-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AUP74_RS09175 192b3da6f30c8eb9e8138b970e2f3ba3 389 SUPERFAMILY SSF50998 35 383 3.3E-81 T 11-11-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AUP74_RS00255 c57ccc6eefd805d8881bcb59be653365 344 PIRSF PIRSF000149 1 335 9.1E-137 T 11-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS00255 c57ccc6eefd805d8881bcb59be653365 344 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 159 313 4.5E-61 T 11-11-2016 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS00255 c57ccc6eefd805d8881bcb59be653365 344 SUPERFAMILY SSF51735 1 179 1.57E-59 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS00255 c57ccc6eefd805d8881bcb59be653365 344 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 152 159 - T 11-11-2016 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS00255 c57ccc6eefd805d8881bcb59be653365 344 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 1.7E-125 T 11-11-2016 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS00255 c57ccc6eefd805d8881bcb59be653365 344 Gene3D G3DSA:3.40.50.720 1 162 7.4E-71 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS00255 c57ccc6eefd805d8881bcb59be653365 344 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 4 154 1.3E-55 T 11-11-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS00255 c57ccc6eefd805d8881bcb59be653365 344 SUPERFAMILY SSF55347 154 314 6.85E-65 T 11-11-2016 AUP74_RS00255 c57ccc6eefd805d8881bcb59be653365 344 Gene3D G3DSA:3.30.360.10 163 315 7.4E-68 T 11-11-2016 AUP74_RS00255 c57ccc6eefd805d8881bcb59be653365 344 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 148 166 2.9E-35 T 11-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS00255 c57ccc6eefd805d8881bcb59be653365 344 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 270 285 2.9E-35 T 11-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS00255 c57ccc6eefd805d8881bcb59be653365 344 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 112 125 2.9E-35 T 11-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS00255 c57ccc6eefd805d8881bcb59be653365 344 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 175 191 2.9E-35 T 11-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS00255 c57ccc6eefd805d8881bcb59be653365 344 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 231 248 2.9E-35 T 11-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS00255 c57ccc6eefd805d8881bcb59be653365 344 SMART SM00846 3 154 5.8E-92 T 11-11-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS12295 67e0a7a604a17a8166f3def5c71e1abf 209 Pfam PF00857 Isochorismatase family 4 190 8.2E-28 T 11-11-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 AUP74_RS12295 67e0a7a604a17a8166f3def5c71e1abf 209 SUPERFAMILY SSF52499 2 199 5.1E-34 T 11-11-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 AUP74_RS12295 67e0a7a604a17a8166f3def5c71e1abf 209 Gene3D G3DSA:3.40.50.850 2 197 2.3E-37 T 11-11-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 AUP74_RS07175 26551c98e06ea36c042840ef44a185ee 316 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 12 256 7.5E-82 T 11-11-2016 IPR017689 Outer membrane protein assembly factor BamD AUP74_RS07175 26551c98e06ea36c042840ef44a185ee 316 Hamap MF_00922 Outer membrane protein assembly factor BamD [bamD]. 10 252 36.783 T 11-11-2016 IPR017689 Outer membrane protein assembly factor BamD AUP74_RS07175 26551c98e06ea36c042840ef44a185ee 316 Gene3D G3DSA:1.25.40.10 41 217 9.1E-4 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS07175 26551c98e06ea36c042840ef44a185ee 316 Pfam PF13525 Outer membrane lipoprotein 41 243 6.4E-71 T 11-11-2016 AUP74_RS07175 26551c98e06ea36c042840ef44a185ee 316 SUPERFAMILY SSF48452 43 128 5.58E-6 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS10685 a514cad6b796a799b6ccda0b1d0db4db 1045 SUPERFAMILY SSF82693 265 320 5.75E-12 T 11-11-2016 AUP74_RS10685 a514cad6b796a799b6ccda0b1d0db4db 1045 SUPERFAMILY SSF82693 140 178 5.75E-12 T 11-11-2016 AUP74_RS10685 a514cad6b796a799b6ccda0b1d0db4db 1045 SUPERFAMILY SSF82866 289 490 1.31E-32 T 11-11-2016 AUP74_RS10685 a514cad6b796a799b6ccda0b1d0db4db 1045 Gene3D G3DSA:3.30.70.1430 43 136 2.6E-18 T 11-11-2016 AUP74_RS10685 a514cad6b796a799b6ccda0b1d0db4db 1045 PRINTS PR00702 Acriflavin resistance protein family signature 381 405 1.8E-16 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS10685 a514cad6b796a799b6ccda0b1d0db4db 1045 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 1.8E-16 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS10685 a514cad6b796a799b6ccda0b1d0db4db 1045 PRINTS PR00702 Acriflavin resistance protein family signature 327 350 1.8E-16 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS10685 a514cad6b796a799b6ccda0b1d0db4db 1045 PRINTS PR00702 Acriflavin resistance protein family signature 464 487 1.8E-16 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS10685 a514cad6b796a799b6ccda0b1d0db4db 1045 Gene3D G3DSA:3.30.70.1430 565 659 5.4E-4 T 11-11-2016 AUP74_RS10685 a514cad6b796a799b6ccda0b1d0db4db 1045 SUPERFAMILY SSF82714 181 264 1.57E-14 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS10685 a514cad6b796a799b6ccda0b1d0db4db 1045 Pfam PF00873 AcrB/AcrD/AcrF family 10 1013 5.0E-163 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS10685 a514cad6b796a799b6ccda0b1d0db4db 1045 SUPERFAMILY SSF82714 713 795 1.29E-12 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS10685 a514cad6b796a799b6ccda0b1d0db4db 1045 Gene3D G3DSA:1.10.3850.10 271 489 2.5E-39 T 11-11-2016 AUP74_RS10685 a514cad6b796a799b6ccda0b1d0db4db 1045 Gene3D G3DSA:1.10.3850.10 801 1015 7.3E-48 T 11-11-2016 AUP74_RS10685 a514cad6b796a799b6ccda0b1d0db4db 1045 Gene3D G3DSA:3.30.2090.10 711 795 4.6E-14 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS10685 a514cad6b796a799b6ccda0b1d0db4db 1045 Gene3D G3DSA:3.30.2090.10 180 265 1.7E-15 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS10685 a514cad6b796a799b6ccda0b1d0db4db 1045 SUPERFAMILY SSF82693 42 130 2.25E-17 T 11-11-2016 AUP74_RS10685 a514cad6b796a799b6ccda0b1d0db4db 1045 SUPERFAMILY SSF82866 793 1015 9.94E-42 T 11-11-2016 AUP74_RS11345 c0f880dc85f0b6c55d9c28791e346494 200 PIRSF PIRSF029811 6 200 8.0E-63 T 11-11-2016 IPR027016 Uncharacterised protein with YceI domain AUP74_RS11345 c0f880dc85f0b6c55d9c28791e346494 200 Pfam PF04264 YceI-like domain 30 195 5.6E-9 T 11-11-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like AUP74_RS11345 c0f880dc85f0b6c55d9c28791e346494 200 SUPERFAMILY SSF101874 28 199 8.63E-16 T 11-11-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like AUP74_RS11345 c0f880dc85f0b6c55d9c28791e346494 200 Gene3D G3DSA:2.40.128.110 27 197 4.7E-9 T 11-11-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like AUP74_RS11345 c0f880dc85f0b6c55d9c28791e346494 200 SMART SM00867 29 198 2.9E-10 T 11-11-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like AUP74_RS14830 bf44e813af5977f915a4c920ba3445f7 233 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 8 226 8.3E-87 T 11-11-2016 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 AUP74_RS14830 bf44e813af5977f915a4c920ba3445f7 233 Gene3D G3DSA:3.40.50.150 19 215 3.3E-50 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS14830 bf44e813af5977f915a4c920ba3445f7 233 SUPERFAMILY SSF53335 10 230 1.5E-48 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS14830 bf44e813af5977f915a4c920ba3445f7 233 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 6 232 39.833 T 11-11-2016 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 AUP74_RS14830 bf44e813af5977f915a4c920ba3445f7 233 Pfam PF13489 Methyltransferase domain 47 198 1.3E-27 T 11-11-2016 AUP74_RS07565 bb98fc46c067b128f075a12d04701e0f 106 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 105 23.571 T 11-11-2016 IPR002765 Uncharacterised protein family UPF0145 AUP74_RS07565 bb98fc46c067b128f075a12d04701e0f 106 Gene3D G3DSA:3.30.110.70 1 105 2.1E-35 T 11-11-2016 IPR002765 Uncharacterised protein family UPF0145 AUP74_RS07565 bb98fc46c067b128f075a12d04701e0f 106 SUPERFAMILY SSF117782 1 105 3.53E-36 T 11-11-2016 IPR002765 Uncharacterised protein family UPF0145 AUP74_RS07565 bb98fc46c067b128f075a12d04701e0f 106 Pfam PF01906 Putative heavy-metal-binding 1 104 4.9E-37 T 11-11-2016 IPR002765 Uncharacterised protein family UPF0145 AUP74_RS09340 7cea7fe98e4738e3992eff9a89157780 164 Pfam PF06271 RDD family 15 152 2.8E-23 T 11-11-2016 IPR010432 RDD AUP74_RS09590 422c0af7a1229865758e4644621be8d4 546 SMART SM00220 11 265 9.6E-50 T 11-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AUP74_RS09590 422c0af7a1229865758e4644621be8d4 546 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 127 139 - T 11-11-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AUP74_RS09590 422c0af7a1229865758e4644621be8d4 546 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 11-11-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 AUP74_RS09590 422c0af7a1229865758e4644621be8d4 546 Gene3D G3DSA:1.10.510.10 120 269 2.1E-42 T 11-11-2016 AUP74_RS09590 422c0af7a1229865758e4644621be8d4 546 Gene3D G3DSA:1.25.40.10 351 505 2.3E-9 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS09590 422c0af7a1229865758e4644621be8d4 546 SUPERFAMILY SSF56112 7 259 1.07E-65 T 11-11-2016 IPR011009 Protein kinase-like domain AUP74_RS09590 422c0af7a1229865758e4644621be8d4 546 SUPERFAMILY SSF48452 376 504 6.64E-8 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS09590 422c0af7a1229865758e4644621be8d4 546 Pfam PF00069 Protein kinase domain 11 258 6.3E-46 T 11-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AUP74_RS09590 422c0af7a1229865758e4644621be8d4 546 Gene3D G3DSA:3.30.200.20 9 119 6.5E-24 T 11-11-2016 AUP74_RS05205 d6d69c7f3d9c10db3cdbed0b508a51bf 209 Gene3D G3DSA:1.10.10.10 123 185 2.2E-21 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS05205 d6d69c7f3d9c10db3cdbed0b508a51bf 209 SUPERFAMILY SSF88659 111 186 1.61E-17 T 11-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS05205 d6d69c7f3d9c10db3cdbed0b508a51bf 209 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 29 185 1.6E-25 T 11-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS05205 d6d69c7f3d9c10db3cdbed0b508a51bf 209 Pfam PF08281 Sigma-70, region 4 130 181 1.3E-18 T 11-11-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS05205 d6d69c7f3d9c10db3cdbed0b508a51bf 209 SUPERFAMILY SSF88946 26 102 9.81E-13 T 11-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS05205 d6d69c7f3d9c10db3cdbed0b508a51bf 209 Pfam PF04542 Sigma-70 region 2 32 96 1.9E-10 T 11-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS05205 d6d69c7f3d9c10db3cdbed0b508a51bf 209 Gene3D G3DSA:1.10.1740.10 28 106 1.9E-12 T 11-11-2016 AUP74_RS01885 a446fa0791d40fa14fdaaaae346b76d3 150 SMART SM00855 1 102 4.0E-8 T 11-11-2016 IPR013078 Histidine phosphatase superfamily, clade-1 AUP74_RS01885 a446fa0791d40fa14fdaaaae346b76d3 150 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 2 70 2.2E-18 T 11-11-2016 IPR013078 Histidine phosphatase superfamily, clade-1 AUP74_RS01885 a446fa0791d40fa14fdaaaae346b76d3 150 SUPERFAMILY SSF53254 2 141 3.14E-23 T 11-11-2016 IPR029033 Histidine phosphatase superfamily AUP74_RS01885 a446fa0791d40fa14fdaaaae346b76d3 150 Gene3D G3DSA:3.40.50.1240 2 133 2.9E-24 T 11-11-2016 IPR029033 Histidine phosphatase superfamily AUP74_RS02960 8d1ec9fcb8f705858f77fbccfec48890 429 Pfam PF13354 Beta-lactamase enzyme family 86 362 2.6E-14 T 11-11-2016 AUP74_RS02960 8d1ec9fcb8f705858f77fbccfec48890 429 SUPERFAMILY SSF56601 81 197 9.01E-20 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS02960 8d1ec9fcb8f705858f77fbccfec48890 429 SUPERFAMILY SSF56601 257 281 9.01E-20 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS02960 8d1ec9fcb8f705858f77fbccfec48890 429 SUPERFAMILY SSF56601 310 392 9.01E-20 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS02960 8d1ec9fcb8f705858f77fbccfec48890 429 Gene3D G3DSA:3.40.710.10 55 195 9.5E-32 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS02960 8d1ec9fcb8f705858f77fbccfec48890 429 Gene3D G3DSA:3.40.710.10 262 412 9.5E-32 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS00210 1aa49124b719b3299601bed045fcd156 304 SUPERFAMILY SSF103481 196 302 1.57E-5 T 11-11-2016 AUP74_RS00210 1aa49124b719b3299601bed045fcd156 304 SUPERFAMILY SSF103481 42 142 5.36E-9 T 11-11-2016 AUP74_RS00210 1aa49124b719b3299601bed045fcd156 304 Pfam PF00892 EamA-like transporter family 9 139 4.7E-19 T 11-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 AUP74_RS00210 1aa49124b719b3299601bed045fcd156 304 Pfam PF00892 EamA-like transporter family 160 297 5.1E-14 T 11-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 AUP74_RS13775 58e978bf5016543664c895e9d746aa91 554 Gene3D G3DSA:3.20.20.140 93 106 1.1E-35 T 11-11-2016 AUP74_RS13775 58e978bf5016543664c895e9d746aa91 554 Gene3D G3DSA:3.20.20.140 221 493 1.1E-35 T 11-11-2016 AUP74_RS13775 58e978bf5016543664c895e9d746aa91 554 SUPERFAMILY SSF51338 509 552 2.44E-11 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS13775 58e978bf5016543664c895e9d746aa91 554 SUPERFAMILY SSF51338 39 84 2.44E-11 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS13775 58e978bf5016543664c895e9d746aa91 554 Gene3D G3DSA:2.30.40.10 494 553 1.0E-6 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS13775 58e978bf5016543664c895e9d746aa91 554 SUPERFAMILY SSF51556 215 509 7.66E-38 T 11-11-2016 IPR032466 Metal-dependent hydrolase AUP74_RS13775 58e978bf5016543664c895e9d746aa91 554 SUPERFAMILY SSF51556 83 139 7.66E-38 T 11-11-2016 IPR032466 Metal-dependent hydrolase AUP74_RS13775 58e978bf5016543664c895e9d746aa91 554 Pfam PF07969 Amidohydrolase family 74 550 3.6E-97 T 11-11-2016 IPR013108 Amidohydrolase 3 AUP74_RS13775 58e978bf5016543664c895e9d746aa91 554 Gene3D G3DSA:2.30.40.10 26 92 5.8E-10 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS00635 d1a3a8af8b64948721c53fe6df516b37 174 SUPERFAMILY SSF88946 8 88 3.45E-15 T 11-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS00635 d1a3a8af8b64948721c53fe6df516b37 174 Gene3D G3DSA:1.10.1740.10 6 77 7.0E-16 T 11-11-2016 AUP74_RS00635 d1a3a8af8b64948721c53fe6df516b37 174 Pfam PF04542 Sigma-70 region 2 12 76 6.3E-13 T 11-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS00635 d1a3a8af8b64948721c53fe6df516b37 174 Pfam PF08281 Sigma-70, region 4 115 167 1.3E-16 T 11-11-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS00635 d1a3a8af8b64948721c53fe6df516b37 174 SUPERFAMILY SSF88659 109 171 6.76E-15 T 11-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS00635 d1a3a8af8b64948721c53fe6df516b37 174 Gene3D G3DSA:1.10.10.10 110 172 4.8E-17 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS00635 d1a3a8af8b64948721c53fe6df516b37 174 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 170 2.4E-24 T 11-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS06790 c265ae40aa4e91b9f4e45c307ec6ab5a 1409 Hamap MF_01323 DNA-directed RNA polymerase subunit gamma [rpoC1]. 13 742 32.15 T 11-11-2016 AUP74_RS06790 c265ae40aa4e91b9f4e45c307ec6ab5a 1409 Pfam PF04983 RNA polymerase Rpb1, domain 3 489 643 3.4E-28 T 11-11-2016 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS06790 c265ae40aa4e91b9f4e45c307ec6ab5a 1409 Pfam PF05000 RNA polymerase Rpb1, domain 4 674 751 1.6E-16 T 11-11-2016 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS06790 c265ae40aa4e91b9f4e45c307ec6ab5a 1409 Pfam PF00623 RNA polymerase Rpb1, domain 2 344 392 1.3E-7 T 11-11-2016 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS06790 c265ae40aa4e91b9f4e45c307ec6ab5a 1409 Pfam PF00623 RNA polymerase Rpb1, domain 2 388 485 1.1E-26 T 11-11-2016 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS06790 c265ae40aa4e91b9f4e45c307ec6ab5a 1409 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 19 1372 0.0 T 11-11-2016 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS06790 c265ae40aa4e91b9f4e45c307ec6ab5a 1409 Gene3D G3DSA:2.40.50.100 1156 1217 3.2E-4 T 11-11-2016 AUP74_RS06790 c265ae40aa4e91b9f4e45c307ec6ab5a 1409 Pfam PF04997 RNA polymerase Rpb1, domain 1 15 342 1.9E-88 T 11-11-2016 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS06790 c265ae40aa4e91b9f4e45c307ec6ab5a 1409 Gene3D G3DSA:2.40.40.20 349 376 2.8E-36 T 11-11-2016 AUP74_RS06790 c265ae40aa4e91b9f4e45c307ec6ab5a 1409 Gene3D G3DSA:2.40.40.20 417 489 2.8E-36 T 11-11-2016 AUP74_RS06790 c265ae40aa4e91b9f4e45c307ec6ab5a 1409 SUPERFAMILY SSF64484 16 944 0.0 T 11-11-2016 AUP74_RS06790 c265ae40aa4e91b9f4e45c307ec6ab5a 1409 SUPERFAMILY SSF64484 1133 1373 0.0 T 11-11-2016 AUP74_RS06790 c265ae40aa4e91b9f4e45c307ec6ab5a 1409 Pfam PF04998 RNA polymerase Rpb1, domain 5 766 1321 5.2E-76 T 11-11-2016 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS06790 c265ae40aa4e91b9f4e45c307ec6ab5a 1409 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 15 1382 10.47 T 11-11-2016 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS06790 c265ae40aa4e91b9f4e45c307ec6ab5a 1409 SMART SM00663 235 514 3.1E-180 T 11-11-2016 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS02510 134699c3296d6fef0e30f51221cf5205 402 SUPERFAMILY SSF53901 1 276 2.75E-61 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS02510 134699c3296d6fef0e30f51221cf5205 402 Gene3D G3DSA:3.40.47.10 186 285 1.2E-56 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS02510 134699c3296d6fef0e30f51221cf5205 402 Gene3D G3DSA:3.40.47.10 5 127 1.2E-56 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS02510 134699c3296d6fef0e30f51221cf5205 402 ProSitePatterns PS00099 Thiolases active site. 383 396 - T 11-11-2016 IPR020610 Thiolase, active site GO:0008152|GO:0016747 AUP74_RS02510 134699c3296d6fef0e30f51221cf5205 402 Gene3D G3DSA:3.40.47.10 148 185 5.6E-58 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS02510 134699c3296d6fef0e30f51221cf5205 402 Gene3D G3DSA:3.40.47.10 286 401 5.6E-58 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS02510 134699c3296d6fef0e30f51221cf5205 402 Pfam PF02803 Thiolase, C-terminal domain 280 401 9.2E-47 T 11-11-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 AUP74_RS02510 134699c3296d6fef0e30f51221cf5205 402 ProSitePatterns PS00737 Thiolases signature 2. 348 364 - T 11-11-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 AUP74_RS02510 134699c3296d6fef0e30f51221cf5205 402 PIRSF PIRSF000429 1 402 1.4E-111 T 11-11-2016 IPR002155 Thiolase GO:0008152|GO:0016747 AUP74_RS02510 134699c3296d6fef0e30f51221cf5205 402 SUPERFAMILY SSF53901 280 401 2.56E-44 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS02510 134699c3296d6fef0e30f51221cf5205 402 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 400 1.0E-130 T 11-11-2016 IPR002155 Thiolase GO:0008152|GO:0016747 AUP74_RS02510 134699c3296d6fef0e30f51221cf5205 402 Pfam PF00108 Thiolase, N-terminal domain 6 227 1.3E-42 T 11-11-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 AUP74_RS02260 500554b3f1e390402dea6f32fa62e75f 225 SUPERFAMILY SSF109755 30 209 2.22E-12 T 11-11-2016 AUP74_RS02260 500554b3f1e390402dea6f32fa62e75f 225 Pfam PF01865 Protein of unknown function DUF47 7 224 1.9E-55 T 11-11-2016 IPR018445 Putative phosphate transport regulator AUP74_RS02260 500554b3f1e390402dea6f32fa62e75f 225 TIGRFAM TIGR00153 TIGR00153: TIGR00153 family protein 5 225 3.1E-50 T 11-11-2016 IPR002727 Protein of unknown function DUF47 AUP74_RS14325 044df093c6c1ff53276c15534b9dbf1e 372 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 136 365 1.7E-18 T 11-11-2016 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 AUP74_RS14325 044df093c6c1ff53276c15534b9dbf1e 372 Gene3D G3DSA:3.20.20.210 3 370 1.5E-62 T 11-11-2016 AUP74_RS14325 044df093c6c1ff53276c15534b9dbf1e 372 SUPERFAMILY SSF51726 9 370 3.14E-50 T 11-11-2016 AUP74_RS00490 2b70b6c7ed80b26b3ffabb61687c457f 491 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 9 20 - T 11-11-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS00490 2b70b6c7ed80b26b3ffabb61687c457f 491 PRINTS PR00987 Glutamyl-tRNA synthetase signature 191 201 4.8E-23 T 11-11-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 AUP74_RS00490 2b70b6c7ed80b26b3ffabb61687c457f 491 PRINTS PR00987 Glutamyl-tRNA synthetase signature 6 18 4.8E-23 T 11-11-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 AUP74_RS00490 2b70b6c7ed80b26b3ffabb61687c457f 491 PRINTS PR00987 Glutamyl-tRNA synthetase signature 35 48 4.8E-23 T 11-11-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 AUP74_RS00490 2b70b6c7ed80b26b3ffabb61687c457f 491 PRINTS PR00987 Glutamyl-tRNA synthetase signature 207 215 4.8E-23 T 11-11-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 AUP74_RS00490 2b70b6c7ed80b26b3ffabb61687c457f 491 PRINTS PR00987 Glutamyl-tRNA synthetase signature 20 31 4.8E-23 T 11-11-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 AUP74_RS00490 2b70b6c7ed80b26b3ffabb61687c457f 491 Hamap MF_00022_B Glutamate--tRNA ligase [gltX]. 3 469 30.348 T 11-11-2016 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 AUP74_RS00490 2b70b6c7ed80b26b3ffabb61687c457f 491 SUPERFAMILY SSF52374 3 306 4.56E-109 T 11-11-2016 AUP74_RS00490 2b70b6c7ed80b26b3ffabb61687c457f 491 Gene3D G3DSA:3.90.800.10 68 192 1.8E-37 T 11-11-2016 AUP74_RS00490 2b70b6c7ed80b26b3ffabb61687c457f 491 Gene3D G3DSA:1.10.10.350 386 469 2.8E-14 T 11-11-2016 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 AUP74_RS00490 2b70b6c7ed80b26b3ffabb61687c457f 491 Gene3D G3DSA:1.10.1160.10 244 327 8.2E-31 T 11-11-2016 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 AUP74_RS00490 2b70b6c7ed80b26b3ffabb61687c457f 491 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 2 466 1.6E-132 T 11-11-2016 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 AUP74_RS00490 2b70b6c7ed80b26b3ffabb61687c457f 491 Gene3D G3DSA:3.40.50.620 2 67 1.6E-49 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS00490 2b70b6c7ed80b26b3ffabb61687c457f 491 Gene3D G3DSA:3.40.50.620 193 242 1.6E-49 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS00490 2b70b6c7ed80b26b3ffabb61687c457f 491 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 3 318 1.9E-109 T 11-11-2016 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 AUP74_RS00490 2b70b6c7ed80b26b3ffabb61687c457f 491 SUPERFAMILY SSF48163 312 469 1.22E-35 T 11-11-2016 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 AUP74_RS04525 e94a9e7d6748f13a9d5ac95e5135d894 693 Gene3D G3DSA:1.10.730.10 584 678 1.2E-5 T 11-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS04525 e94a9e7d6748f13a9d5ac95e5135d894 693 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 5 551 1.7E-216 T 11-11-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AUP74_RS04525 e94a9e7d6748f13a9d5ac95e5135d894 693 Pfam PF05746 DALR anticodon binding domain 583 680 1.5E-8 T 11-11-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 AUP74_RS04525 e94a9e7d6748f13a9d5ac95e5135d894 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 393 412 9.5E-35 T 11-11-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AUP74_RS04525 e94a9e7d6748f13a9d5ac95e5135d894 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 245 260 9.5E-35 T 11-11-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AUP74_RS04525 e94a9e7d6748f13a9d5ac95e5135d894 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 49 61 9.5E-35 T 11-11-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AUP74_RS04525 e94a9e7d6748f13a9d5ac95e5135d894 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 317 333 9.5E-35 T 11-11-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AUP74_RS04525 e94a9e7d6748f13a9d5ac95e5135d894 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 6 19 9.5E-35 T 11-11-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AUP74_RS04525 e94a9e7d6748f13a9d5ac95e5135d894 693 SUPERFAMILY SSF109604 338 496 1.07E-18 T 11-11-2016 AUP74_RS04525 e94a9e7d6748f13a9d5ac95e5135d894 693 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 2 689 1.4E-254 T 11-11-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AUP74_RS04525 e94a9e7d6748f13a9d5ac95e5135d894 693 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 2 689 26.621 T 11-11-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AUP74_RS08355 5f78f863e858d7a8479e17fb3e440ed6 332 Pfam PF00296 Luciferase-like monooxygenase 16 301 1.3E-35 T 11-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AUP74_RS08355 5f78f863e858d7a8479e17fb3e440ed6 332 SUPERFAMILY SSF51679 4 324 4.71E-83 T 11-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AUP74_RS08355 5f78f863e858d7a8479e17fb3e440ed6 332 Gene3D G3DSA:3.20.20.30 5 323 3.6E-88 T 11-11-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AUP74_RS08355 5f78f863e858d7a8479e17fb3e440ed6 332 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 5 322 2.4E-131 T 11-11-2016 IPR019949 Luciferase family oxidoreductase, group 1 AUP74_RS03025 1138463886b3c90362d1a83c464e4b9b 1045 SUPERFAMILY SSF82714 181 263 5.36E-14 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS03025 1138463886b3c90362d1a83c464e4b9b 1045 Pfam PF00873 AcrB/AcrD/AcrF family 5 1021 3.0E-168 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS03025 1138463886b3c90362d1a83c464e4b9b 1045 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 3.5E-21 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS03025 1138463886b3c90362d1a83c464e4b9b 1045 PRINTS PR00702 Acriflavin resistance protein family signature 327 350 3.5E-21 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS03025 1138463886b3c90362d1a83c464e4b9b 1045 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 3.5E-21 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS03025 1138463886b3c90362d1a83c464e4b9b 1045 PRINTS PR00702 Acriflavin resistance protein family signature 459 482 3.5E-21 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS03025 1138463886b3c90362d1a83c464e4b9b 1045 PRINTS PR00702 Acriflavin resistance protein family signature 381 405 3.5E-21 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS03025 1138463886b3c90362d1a83c464e4b9b 1045 PRINTS PR00702 Acriflavin resistance protein family signature 434 457 3.5E-21 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS03025 1138463886b3c90362d1a83c464e4b9b 1045 Gene3D G3DSA:3.30.2090.10 724 796 5.5E-10 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS03025 1138463886b3c90362d1a83c464e4b9b 1045 Gene3D G3DSA:3.30.70.1430 43 140 4.4E-20 T 11-11-2016 AUP74_RS03025 1138463886b3c90362d1a83c464e4b9b 1045 SUPERFAMILY SSF82866 290 484 3.01E-35 T 11-11-2016 AUP74_RS03025 1138463886b3c90362d1a83c464e4b9b 1045 Gene3D G3DSA:3.30.2090.10 180 265 8.9E-12 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS03025 1138463886b3c90362d1a83c464e4b9b 1045 Gene3D G3DSA:3.30.70.1320 267 304 2.9E-11 T 11-11-2016 AUP74_RS03025 1138463886b3c90362d1a83c464e4b9b 1045 Gene3D G3DSA:3.30.70.1320 154 175 2.9E-11 T 11-11-2016 AUP74_RS03025 1138463886b3c90362d1a83c464e4b9b 1045 SUPERFAMILY SSF82714 725 797 6.15E-9 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS03025 1138463886b3c90362d1a83c464e4b9b 1045 Gene3D G3DSA:1.20.1640.10 305 490 2.6E-38 T 11-11-2016 AUP74_RS03025 1138463886b3c90362d1a83c464e4b9b 1045 Gene3D G3DSA:1.10.3850.10 804 1021 2.8E-55 T 11-11-2016 AUP74_RS03025 1138463886b3c90362d1a83c464e4b9b 1045 SUPERFAMILY SSF82693 42 130 3.92E-17 T 11-11-2016 AUP74_RS03025 1138463886b3c90362d1a83c464e4b9b 1045 SUPERFAMILY SSF82693 265 321 8.89E-16 T 11-11-2016 AUP74_RS03025 1138463886b3c90362d1a83c464e4b9b 1045 SUPERFAMILY SSF82693 136 178 8.89E-16 T 11-11-2016 AUP74_RS03025 1138463886b3c90362d1a83c464e4b9b 1045 SUPERFAMILY SSF82866 798 1021 6.54E-47 T 11-11-2016 AUP74_RS15570 0d440cc628fc8d0afe67bb6f18a055d2 470 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 269 282 - T 11-11-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AUP74_RS15570 0d440cc628fc8d0afe67bb6f18a055d2 470 Gene3D G3DSA:1.10.260.30 329 431 1.9E-38 T 11-11-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 AUP74_RS15570 0d440cc628fc8d0afe67bb6f18a055d2 470 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 449 34.493 T 11-11-2016 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 AUP74_RS15570 0d440cc628fc8d0afe67bb6f18a055d2 470 Gene3D G3DSA:1.20.120.140 2 88 1.9E-35 T 11-11-2016 AUP74_RS15570 0d440cc628fc8d0afe67bb6f18a055d2 470 SMART SM00963 1 86 5.9E-35 T 11-11-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AUP74_RS15570 0d440cc628fc8d0afe67bb6f18a055d2 470 Pfam PF00448 SRP54-type protein, GTPase domain 100 296 8.1E-74 T 11-11-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AUP74_RS15570 0d440cc628fc8d0afe67bb6f18a055d2 470 Pfam PF02978 Signal peptide binding domain 329 427 1.0E-32 T 11-11-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 AUP74_RS15570 0d440cc628fc8d0afe67bb6f18a055d2 470 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 429 2.1E-178 T 11-11-2016 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 AUP74_RS15570 0d440cc628fc8d0afe67bb6f18a055d2 470 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 2.5E-22 T 11-11-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AUP74_RS15570 0d440cc628fc8d0afe67bb6f18a055d2 470 SMART SM00382 99 301 5.1E-10 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS15570 0d440cc628fc8d0afe67bb6f18a055d2 470 SMART SM00962 100 296 1.9E-114 T 11-11-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AUP74_RS15570 0d440cc628fc8d0afe67bb6f18a055d2 470 SUPERFAMILY SSF52540 42 352 1.86E-56 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS15570 0d440cc628fc8d0afe67bb6f18a055d2 470 SUPERFAMILY SSF47446 298 430 6.11E-44 T 11-11-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 AUP74_RS15570 0d440cc628fc8d0afe67bb6f18a055d2 470 Gene3D G3DSA:3.40.50.300 94 297 5.8E-76 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS16515 a7bbdd1a7de34cae9de2fee928474e08 1287 SUPERFAMILY SSF56042 816 1025 1.42E-54 T 11-11-2016 IPR010918 AIR synthase-related protein, C-terminal domain AUP74_RS16515 a7bbdd1a7de34cae9de2fee928474e08 1287 SUPERFAMILY SSF55326 219 421 2.41E-59 T 11-11-2016 AUP74_RS16515 a7bbdd1a7de34cae9de2fee928474e08 1287 Hamap MF_00419 Phosphoribosylformylglycinamidine synthase [purL]. 1 1287 21.073 T 11-11-2016 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AUP74_RS16515 a7bbdd1a7de34cae9de2fee928474e08 1287 SMART SM01211 1031 1286 6.9E-148 T 11-11-2016 AUP74_RS16515 a7bbdd1a7de34cae9de2fee928474e08 1287 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 1031 1286 1.8E-103 T 11-11-2016 AUP74_RS16515 a7bbdd1a7de34cae9de2fee928474e08 1287 TIGRFAM TIGR01735 FGAM_synt: phosphoribosylformylglycinamidine synthase 3 1285 0.0 T 11-11-2016 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AUP74_RS16515 a7bbdd1a7de34cae9de2fee928474e08 1287 SUPERFAMILY SSF55326 615 810 1.88E-68 T 11-11-2016 AUP74_RS16515 a7bbdd1a7de34cae9de2fee928474e08 1287 SUPERFAMILY SSF109736 155 218 1.2E-21 T 11-11-2016 AUP74_RS16515 a7bbdd1a7de34cae9de2fee928474e08 1287 Pfam PF02769 AIR synthase related protein, C-terminal domain 425 579 1.4E-29 T 11-11-2016 IPR010918 AIR synthase-related protein, C-terminal domain AUP74_RS16515 a7bbdd1a7de34cae9de2fee928474e08 1287 Pfam PF02769 AIR synthase related protein, C-terminal domain 829 958 2.1E-14 T 11-11-2016 IPR010918 AIR synthase-related protein, C-terminal domain AUP74_RS16515 a7bbdd1a7de34cae9de2fee928474e08 1287 Gene3D G3DSA:3.40.50.880 1031 1260 2.9E-11 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS16515 a7bbdd1a7de34cae9de2fee928474e08 1287 Gene3D G3DSA:3.30.1330.10 209 415 3.9E-38 T 11-11-2016 IPR016188 PurM-like, N-terminal domain AUP74_RS16515 a7bbdd1a7de34cae9de2fee928474e08 1287 Gene3D G3DSA:3.30.1330.10 639 803 8.2E-18 T 11-11-2016 IPR016188 PurM-like, N-terminal domain AUP74_RS16515 a7bbdd1a7de34cae9de2fee928474e08 1287 SUPERFAMILY SSF56042 424 609 1.18E-53 T 11-11-2016 IPR010918 AIR synthase-related protein, C-terminal domain AUP74_RS16515 a7bbdd1a7de34cae9de2fee928474e08 1287 SUPERFAMILY SSF52317 1028 1285 3.96E-95 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS16515 a7bbdd1a7de34cae9de2fee928474e08 1287 SUPERFAMILY SSF82697 1 149 2.04E-47 T 11-11-2016 AUP74_RS14375 a0fc53fe1176a848402861dd0e3d2ea2 389 SUPERFAMILY SSF56645 6 246 3.53E-69 T 11-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 AUP74_RS14375 a0fc53fe1176a848402861dd0e3d2ea2 389 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 122 134 - T 11-11-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AUP74_RS14375 a0fc53fe1176a848402861dd0e3d2ea2 389 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 115 1.5E-26 T 11-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 AUP74_RS14375 a0fc53fe1176a848402861dd0e3d2ea2 389 Gene3D G3DSA:1.10.540.10 6 116 7.3E-30 T 11-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 AUP74_RS14375 a0fc53fe1176a848402861dd0e3d2ea2 389 Gene3D G3DSA:1.20.140.10 223 384 8.4E-66 T 11-11-2016 AUP74_RS14375 a0fc53fe1176a848402861dd0e3d2ea2 389 SUPERFAMILY SSF47203 233 384 5.32E-54 T 11-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AUP74_RS14375 a0fc53fe1176a848402861dd0e3d2ea2 389 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 221 3.0E-21 T 11-11-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 AUP74_RS14375 a0fc53fe1176a848402861dd0e3d2ea2 389 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 383 3.2E-49 T 11-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AUP74_RS14375 a0fc53fe1176a848402861dd0e3d2ea2 389 Gene3D G3DSA:2.40.110.10 120 222 8.7E-34 T 11-11-2016 AUP74_RS14120 46da5f8d1632226623be69b2dea67143 178 SUPERFAMILY SSF46689 4 74 1.07E-14 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS14120 46da5f8d1632226623be69b2dea67143 178 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 2.6E-8 T 11-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AUP74_RS14120 46da5f8d1632226623be69b2dea67143 178 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 2.6E-8 T 11-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AUP74_RS14120 46da5f8d1632226623be69b2dea67143 178 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 55 1.0E-13 T 11-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AUP74_RS14120 46da5f8d1632226623be69b2dea67143 178 Gene3D G3DSA:1.10.357.10 6 173 1.6E-26 T 11-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 AUP74_RS10265 49a0324c64d6f630f2abbf23249d65f2 115 Pfam PF01230 HIT domain 13 107 2.9E-24 T 11-11-2016 IPR001310 Histidine triad (HIT) protein AUP74_RS10265 49a0324c64d6f630f2abbf23249d65f2 115 SUPERFAMILY SSF54197 3 108 3.4E-31 T 11-11-2016 IPR011146 HIT-like domain GO:0003824 AUP74_RS10265 49a0324c64d6f630f2abbf23249d65f2 115 Gene3D G3DSA:3.30.428.10 3 109 2.2E-31 T 11-11-2016 IPR011146 HIT-like domain GO:0003824 AUP74_RS10265 49a0324c64d6f630f2abbf23249d65f2 115 ProSitePatterns PS00892 HIT domain signature. 86 104 - T 11-11-2016 IPR019808 Histidine triad, conserved site AUP74_RS10265 49a0324c64d6f630f2abbf23249d65f2 115 PRINTS PR00332 Histidine triad family signature 27 45 1.7E-14 T 11-11-2016 IPR001310 Histidine triad (HIT) protein AUP74_RS10265 49a0324c64d6f630f2abbf23249d65f2 115 PRINTS PR00332 Histidine triad family signature 93 103 1.7E-14 T 11-11-2016 IPR001310 Histidine triad (HIT) protein AUP74_RS10265 49a0324c64d6f630f2abbf23249d65f2 115 PRINTS PR00332 Histidine triad family signature 6 22 1.7E-14 T 11-11-2016 IPR001310 Histidine triad (HIT) protein AUP74_RS00715 fe1b52abc42752a2b2369fefc0d57eeb 512 Gene3D G3DSA:1.20.1250.20 285 494 6.4E-11 T 11-11-2016 AUP74_RS00715 fe1b52abc42752a2b2369fefc0d57eeb 512 Gene3D G3DSA:1.20.1250.20 34 194 5.3E-14 T 11-11-2016 AUP74_RS00715 fe1b52abc42752a2b2369fefc0d57eeb 512 ProSitePatterns PS01022 PTR2 family proton/oligopeptide symporters signature 1. 78 102 - T 11-11-2016 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 AUP74_RS00715 fe1b52abc42752a2b2369fefc0d57eeb 512 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 11 484 2.2E-118 T 11-11-2016 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 AUP74_RS00715 fe1b52abc42752a2b2369fefc0d57eeb 512 Pfam PF00854 POT family 90 454 5.2E-65 T 11-11-2016 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 AUP74_RS00715 fe1b52abc42752a2b2369fefc0d57eeb 512 SUPERFAMILY SSF103473 275 492 5.84E-30 T 11-11-2016 IPR020846 Major facilitator superfamily domain AUP74_RS00715 fe1b52abc42752a2b2369fefc0d57eeb 512 SUPERFAMILY SSF103473 14 206 5.84E-30 T 11-11-2016 IPR020846 Major facilitator superfamily domain AUP74_RS14610 8774866fe0f753bac2f5cf6797a2bc14 268 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 260 1.2E-46 T 11-11-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 AUP74_RS14610 8774866fe0f753bac2f5cf6797a2bc14 268 SUPERFAMILY SSF52096 1 261 9.37E-64 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS14610 8774866fe0f753bac2f5cf6797a2bc14 268 Gene3D G3DSA:3.90.226.10 1 257 1.4E-62 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS14610 8774866fe0f753bac2f5cf6797a2bc14 268 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 11-11-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 AUP74_RS06010 53990fbac677a25d9469499750b35bbe 645 Pfam PF00501 AMP-binding enzyme 88 519 8.5E-91 T 11-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 AUP74_RS06010 53990fbac677a25d9469499750b35bbe 645 Pfam PF13193 AMP-binding enzyme C-terminal domain 528 606 2.2E-21 T 11-11-2016 IPR025110 AMP-binding enzyme C-terminal domain AUP74_RS06010 53990fbac677a25d9469499750b35bbe 645 Gene3D G3DSA:3.40.50.980 78 263 1.1E-45 T 11-11-2016 AUP74_RS06010 53990fbac677a25d9469499750b35bbe 645 SUPERFAMILY SSF56801 17 639 6.02E-182 T 11-11-2016 AUP74_RS06010 53990fbac677a25d9469499750b35bbe 645 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 24 80 2.1E-20 T 11-11-2016 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 AUP74_RS06010 53990fbac677a25d9469499750b35bbe 645 Gene3D G3DSA:3.30.300.30 515 635 1.1E-23 T 11-11-2016 AUP74_RS06010 53990fbac677a25d9469499750b35bbe 645 Gene3D G3DSA:2.30.38.10 436 513 9.8E-8 T 11-11-2016 AUP74_RS06010 53990fbac677a25d9469499750b35bbe 645 ProSitePatterns PS00455 Putative AMP-binding domain signature. 258 269 - T 11-11-2016 IPR020845 AMP-binding, conserved site AUP74_RS06010 53990fbac677a25d9469499750b35bbe 645 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 20 640 0.0 T 11-11-2016 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: R-HSA-71384 AUP74_RS06010 53990fbac677a25d9469499750b35bbe 645 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 2 642 53.1 T 11-11-2016 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: R-HSA-71384 AUP74_RS06010 53990fbac677a25d9469499750b35bbe 645 Gene3D G3DSA:3.40.50.980 264 421 3.8E-26 T 11-11-2016 AUP74_RS07840 ea1ad08cf9220511ddd598386030ca31 487 ProSitePatterns PS00691 DNA photolyases class 1 signature 2. 366 385 - T 11-11-2016 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal AUP74_RS07840 ea1ad08cf9220511ddd598386030ca31 487 SUPERFAMILY SSF52425 10 192 3.53E-50 T 11-11-2016 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 AUP74_RS07840 ea1ad08cf9220511ddd598386030ca31 487 Pfam PF00875 DNA photolyase 11 180 1.4E-46 T 11-11-2016 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 AUP74_RS07840 ea1ad08cf9220511ddd598386030ca31 487 Pfam PF03441 FAD binding domain of DNA photolyase 296 483 1.4E-80 T 11-11-2016 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 AUP74_RS07840 ea1ad08cf9220511ddd598386030ca31 487 SUPERFAMILY SSF48173 221 486 9.03E-102 T 11-11-2016 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 AUP74_RS07840 ea1ad08cf9220511ddd598386030ca31 487 PRINTS PR00147 DNA photolyase signature 150 166 1.9E-27 T 11-11-2016 IPR002081 Cryptochrome/DNA photolyase class 1 AUP74_RS07840 ea1ad08cf9220511ddd598386030ca31 487 PRINTS PR00147 DNA photolyase signature 346 362 1.9E-27 T 11-11-2016 IPR002081 Cryptochrome/DNA photolyase class 1 AUP74_RS07840 ea1ad08cf9220511ddd598386030ca31 487 PRINTS PR00147 DNA photolyase signature 366 384 1.9E-27 T 11-11-2016 IPR002081 Cryptochrome/DNA photolyase class 1 AUP74_RS07840 ea1ad08cf9220511ddd598386030ca31 487 PRINTS PR00147 DNA photolyase signature 405 419 1.9E-27 T 11-11-2016 IPR002081 Cryptochrome/DNA photolyase class 1 AUP74_RS07840 ea1ad08cf9220511ddd598386030ca31 487 Gene3D G3DSA:1.25.40.80 155 307 5.2E-40 T 11-11-2016 AUP74_RS07840 ea1ad08cf9220511ddd598386030ca31 487 Gene3D G3DSA:1.10.579.10 308 485 2.3E-71 T 11-11-2016 AUP74_RS07840 ea1ad08cf9220511ddd598386030ca31 487 Gene3D G3DSA:3.40.50.620 7 154 8.5E-46 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS01330 6052731a3d6f127dadacfdb7f15f6cc6 377 SUPERFAMILY SSF50129 323 374 8.47E-12 T 11-11-2016 IPR011032 GroES-like AUP74_RS01330 6052731a3d6f127dadacfdb7f15f6cc6 377 Gene3D G3DSA:3.90.180.10 4 194 1.2E-70 T 11-11-2016 IPR011032 GroES-like AUP74_RS01330 6052731a3d6f127dadacfdb7f15f6cc6 377 Gene3D G3DSA:3.40.50.720 195 313 1.3E-42 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS01330 6052731a3d6f127dadacfdb7f15f6cc6 377 SUPERFAMILY SSF50129 5 189 5.33E-76 T 11-11-2016 IPR011032 GroES-like AUP74_RS01330 6052731a3d6f127dadacfdb7f15f6cc6 377 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 66 80 - T 11-11-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 AUP74_RS01330 6052731a3d6f127dadacfdb7f15f6cc6 377 Pfam PF00107 Zinc-binding dehydrogenase 202 328 5.0E-26 T 11-11-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AUP74_RS01330 6052731a3d6f127dadacfdb7f15f6cc6 377 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 33 159 5.8E-25 T 11-11-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AUP74_RS01330 6052731a3d6f127dadacfdb7f15f6cc6 377 SUPERFAMILY SSF51735 165 338 9.63E-48 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS01330 6052731a3d6f127dadacfdb7f15f6cc6 377 TIGRFAM TIGR02818 adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 7 374 7.4E-220 T 11-11-2016 IPR014183 Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase GO:0006069|GO:0008270|GO:0051903|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00620+1.1.1.28|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00680+1.1.1.284|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-1801|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6454|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-6901|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396|Reactome: R-HSA-71384 AUP74_RS03185 4d828e8e7a0e0f5736fdfb2908dfc69c 154 SUPERFAMILY SSF54637 3 142 6.08E-29 T 11-11-2016 IPR029069 HotDog domain AUP74_RS03185 4d828e8e7a0e0f5736fdfb2908dfc69c 154 Pfam PF13279 Thioesterase-like superfamily 15 131 8.8E-6 T 11-11-2016 AUP74_RS03185 4d828e8e7a0e0f5736fdfb2908dfc69c 154 Gene3D G3DSA:3.10.129.10 3 139 5.6E-28 T 11-11-2016 IPR029069 HotDog domain AUP74_RS06950 447f9f914a43d50856f8bca3ba133e60 334 Gene3D G3DSA:1.10.150.20 244 325 7.1E-37 T 11-11-2016 AUP74_RS06950 447f9f914a43d50856f8bca3ba133e60 334 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 29 227 1.9E-24 T 11-11-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS06950 447f9f914a43d50856f8bca3ba133e60 334 SMART SM00662 23 233 1.0E-104 T 11-11-2016 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS06950 447f9f914a43d50856f8bca3ba133e60 334 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 246 307 7.0E-24 T 11-11-2016 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS06950 447f9f914a43d50856f8bca3ba133e60 334 SUPERFAMILY SSF56553 53 177 4.32E-43 T 11-11-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS06950 447f9f914a43d50856f8bca3ba133e60 334 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 255 328 3.0E-35 T 11-11-2016 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS06950 447f9f914a43d50856f8bca3ba133e60 334 SUPERFAMILY SSF47789 250 323 6.93E-26 T 11-11-2016 AUP74_RS06950 447f9f914a43d50856f8bca3ba133e60 334 Gene3D G3DSA:2.170.120.12 66 176 2.4E-42 T 11-11-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS06950 447f9f914a43d50856f8bca3ba133e60 334 Gene3D G3DSA:3.30.1360.10 10 65 3.5E-10 T 11-11-2016 AUP74_RS06950 447f9f914a43d50856f8bca3ba133e60 334 SUPERFAMILY SSF55257 6 53 5.99E-33 T 11-11-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS06950 447f9f914a43d50856f8bca3ba133e60 334 SUPERFAMILY SSF55257 178 232 5.99E-33 T 11-11-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS06950 447f9f914a43d50856f8bca3ba133e60 334 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 24 315 4.7E-113 T 11-11-2016 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS06950 447f9f914a43d50856f8bca3ba133e60 334 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 5 316 36.29 T 11-11-2016 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS06950 447f9f914a43d50856f8bca3ba133e60 334 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 60 155 1.2E-25 T 11-11-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS00295 e3c816b9bcc8b5ad575552a465e1b220 375 PIRSF PIRSF038994 14 375 4.7E-105 T 11-11-2016 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 AUP74_RS00295 e3c816b9bcc8b5ad575552a465e1b220 375 SUPERFAMILY SSF51338 11 50 3.93E-7 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS00295 e3c816b9bcc8b5ad575552a465e1b220 375 SUPERFAMILY SSF51338 343 373 3.93E-7 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS00295 e3c816b9bcc8b5ad575552a465e1b220 375 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 46 369 3.3E-86 T 11-11-2016 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 AUP74_RS00295 e3c816b9bcc8b5ad575552a465e1b220 375 SUPERFAMILY SSF51556 51 341 6.24E-96 T 11-11-2016 IPR032466 Metal-dependent hydrolase AUP74_RS00295 e3c816b9bcc8b5ad575552a465e1b220 375 Gene3D G3DSA:3.20.20.140 51 341 1.3E-92 T 11-11-2016 AUP74_RS00295 e3c816b9bcc8b5ad575552a465e1b220 375 Pfam PF01979 Amidohydrolase family 48 372 1.3E-21 T 11-11-2016 IPR006680 Amidohydrolase-related GO:0016787 AUP74_RS02220 c261cf427fc41cda24a307276f503ec6 363 SUPERFAMILY SSF53756 2 361 4.71E-66 T 11-11-2016 AUP74_RS02220 c261cf427fc41cda24a307276f503ec6 363 Gene3D G3DSA:3.40.50.2000 155 342 1.0E-31 T 11-11-2016 AUP74_RS02220 c261cf427fc41cda24a307276f503ec6 363 Pfam PF00534 Glycosyl transferases group 1 181 342 7.5E-35 T 11-11-2016 IPR001296 Glycosyl transferase, family 1 AUP74_RS02220 c261cf427fc41cda24a307276f503ec6 363 Pfam PF13439 Glycosyltransferase Family 4 14 161 2.6E-14 T 11-11-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AUP74_RS02115 8d2cca08a9810d115b9a70c4ff393b2c 453 Pfam PF00271 Helicase conserved C-terminal domain 232 338 1.6E-28 T 11-11-2016 IPR001650 Helicase, C-terminal AUP74_RS02115 8d2cca08a9810d115b9a70c4ff393b2c 453 Pfam PF00270 DEAD/DEAH box helicase 25 193 3.2E-48 T 11-11-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AUP74_RS02115 8d2cca08a9810d115b9a70c4ff393b2c 453 SMART SM00490 257 338 3.2E-32 T 11-11-2016 IPR001650 Helicase, C-terminal AUP74_RS02115 8d2cca08a9810d115b9a70c4ff393b2c 453 Gene3D G3DSA:3.40.50.300 212 376 3.5E-53 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS02115 8d2cca08a9810d115b9a70c4ff393b2c 453 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 152 160 - T 11-11-2016 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site AUP74_RS02115 8d2cca08a9810d115b9a70c4ff393b2c 453 SMART SM00487 20 221 7.5E-61 T 11-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain AUP74_RS02115 8d2cca08a9810d115b9a70c4ff393b2c 453 Hamap MF_00968 ATP-dependent RNA helicase RhlE [rhlE]. 1 448 49.844 T 11-11-2016 IPR028622 ATP-dependent RNA helicase RhlE GO:0004004|GO:0042255 AUP74_RS02115 8d2cca08a9810d115b9a70c4ff393b2c 453 SUPERFAMILY SSF52540 73 359 2.0E-75 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS02115 8d2cca08a9810d115b9a70c4ff393b2c 453 Gene3D G3DSA:3.40.50.300 3 211 3.8E-80 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS16775 b2d4ca7da614874c31b7fd6fba2458f8 313 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 6 307 38.938 T 11-11-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AUP74_RS16775 b2d4ca7da614874c31b7fd6fba2458f8 313 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 2 306 1.5E-114 T 11-11-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AUP74_RS16775 b2d4ca7da614874c31b7fd6fba2458f8 313 PIRSF PIRSF004486 1 308 1.6E-104 T 11-11-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AUP74_RS16775 b2d4ca7da614874c31b7fd6fba2458f8 313 SUPERFAMILY SSF81799 113 212 9.81E-38 T 11-11-2016 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AUP74_RS16775 b2d4ca7da614874c31b7fd6fba2458f8 313 SUPERFAMILY SSF53335 212 307 7.29E-45 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS16775 b2d4ca7da614874c31b7fd6fba2458f8 313 SUPERFAMILY SSF53335 6 112 7.29E-45 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS16775 b2d4ca7da614874c31b7fd6fba2458f8 313 Gene3D G3DSA:3.40.50.150 215 307 3.5E-48 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS16775 b2d4ca7da614874c31b7fd6fba2458f8 313 Gene3D G3DSA:3.40.50.150 6 109 3.5E-48 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS16775 b2d4ca7da614874c31b7fd6fba2458f8 313 Gene3D G3DSA:1.10.150.170 112 214 3.4E-39 T 11-11-2016 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AUP74_RS16775 b2d4ca7da614874c31b7fd6fba2458f8 313 Pfam PF01795 MraW methylase family 5 306 2.4E-113 T 11-11-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AUP74_RS06390 60ae263f9e38411190ceeff654a28927 640 SMART SM00763 19 376 4.4E-213 T 11-11-2016 IPR013153 PrkA AAA domain AUP74_RS06390 60ae263f9e38411190ceeff654a28927 640 Pfam PF08298 PrkA AAA domain 20 376 4.8E-176 T 11-11-2016 IPR013153 PrkA AAA domain AUP74_RS06390 60ae263f9e38411190ceeff654a28927 640 Pfam PF06798 PrkA serine protein kinase C-terminal domain 379 632 1.9E-77 T 11-11-2016 IPR010650 PrkA C-terminal domain AUP74_RS06390 60ae263f9e38411190ceeff654a28927 640 PIRSF PIRSF000549 1 640 7.4E-290 T 11-11-2016 IPR016230 Serine-protein kinase, PrkA GO:0004672 AUP74_RS06390 60ae263f9e38411190ceeff654a28927 640 SUPERFAMILY SSF52540 75 363 1.41E-17 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS06390 60ae263f9e38411190ceeff654a28927 640 Gene3D G3DSA:3.40.50.300 75 154 1.2E-8 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS06390 60ae263f9e38411190ceeff654a28927 640 Gene3D G3DSA:3.40.50.300 239 325 1.2E-8 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS13445 aacc8fd7b0fb5f5a37aef97de799ba38 122 Gene3D G3DSA:3.40.50.10600 1 119 1.1E-24 T 11-11-2016 IPR021866 SpoIIAA-like AUP74_RS13445 aacc8fd7b0fb5f5a37aef97de799ba38 122 Pfam PF11964 SpoIIAA-like 12 118 2.0E-10 T 11-11-2016 IPR021866 SpoIIAA-like AUP74_RS13445 aacc8fd7b0fb5f5a37aef97de799ba38 122 SUPERFAMILY SSF52091 1 118 5.89E-25 T 11-11-2016 IPR002645 STAS domain AUP74_RS01275 90e9fb756ea1a308db0e340caf5a8cc1 302 Pfam PF03466 LysR substrate binding domain 98 300 1.8E-15 T 11-11-2016 IPR005119 LysR, substrate-binding AUP74_RS01275 90e9fb756ea1a308db0e340caf5a8cc1 302 Gene3D G3DSA:3.40.190.10 98 173 4.2E-25 T 11-11-2016 AUP74_RS01275 90e9fb756ea1a308db0e340caf5a8cc1 302 Gene3D G3DSA:3.40.190.10 275 301 4.2E-25 T 11-11-2016 AUP74_RS01275 90e9fb756ea1a308db0e340caf5a8cc1 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 66 6.7E-17 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS01275 90e9fb756ea1a308db0e340caf5a8cc1 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 4.1E-7 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS01275 90e9fb756ea1a308db0e340caf5a8cc1 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 4.1E-7 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS01275 90e9fb756ea1a308db0e340caf5a8cc1 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 4.1E-7 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS01275 90e9fb756ea1a308db0e340caf5a8cc1 302 SUPERFAMILY SSF53850 99 299 1.81E-31 T 11-11-2016 AUP74_RS01275 90e9fb756ea1a308db0e340caf5a8cc1 302 Gene3D G3DSA:1.10.10.10 1 85 5.2E-27 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS01275 90e9fb756ea1a308db0e340caf5a8cc1 302 Gene3D G3DSA:3.40.190.10 174 270 1.2E-21 T 11-11-2016 AUP74_RS01275 90e9fb756ea1a308db0e340caf5a8cc1 302 SUPERFAMILY SSF46785 3 85 1.03E-18 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS02105 476e3b5179384f7ae15fbefabc99ef5e 101 Pfam PF13432 Tetratricopeptide repeat 21 77 1.2E-5 T 11-11-2016 AUP74_RS02105 476e3b5179384f7ae15fbefabc99ef5e 101 Gene3D G3DSA:1.25.40.10 7 94 2.6E-12 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS02105 476e3b5179384f7ae15fbefabc99ef5e 101 SUPERFAMILY SSF48452 4 84 1.76E-12 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS02105 476e3b5179384f7ae15fbefabc99ef5e 101 SMART SM00028 16 49 29.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS02105 476e3b5179384f7ae15fbefabc99ef5e 101 SMART SM00028 50 83 2.6 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS14615 abb59783ad585f0ee4a71b302f151c1f 435 Pfam PF01425 Amidase 6 416 1.9E-81 T 11-11-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AUP74_RS14615 abb59783ad585f0ee4a71b302f151c1f 435 Gene3D G3DSA:3.90.1300.10 1 427 5.3E-114 T 11-11-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AUP74_RS14615 abb59783ad585f0ee4a71b302f151c1f 435 SUPERFAMILY SSF75304 1 427 4.19E-108 T 11-11-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AUP74_RS14725 7125b4a136810ace9de62cd13759b884 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 2.5E-18 T 11-11-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 AUP74_RS14725 7125b4a136810ace9de62cd13759b884 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 2.5E-18 T 11-11-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 AUP74_RS14725 7125b4a136810ace9de62cd13759b884 65 PRINTS PR00064 Ribosomal protein L35 signature 4 21 2.5E-18 T 11-11-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 AUP74_RS14725 7125b4a136810ace9de62cd13759b884 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 4 63 2.6E-20 T 11-11-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 AUP74_RS14725 7125b4a136810ace9de62cd13759b884 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 2 64 14.397 T 11-11-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 AUP74_RS14725 7125b4a136810ace9de62cd13759b884 65 SUPERFAMILY SSF143034 4 62 1.96E-18 T 11-11-2016 AUP74_RS14725 7125b4a136810ace9de62cd13759b884 65 Pfam PF01632 Ribosomal protein L35 4 62 9.7E-22 T 11-11-2016 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS14725 7125b4a136810ace9de62cd13759b884 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 6 31 - T 11-11-2016 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS01455 ec3f773e2efb166ad49266dc04668f74 361 SUPERFAMILY SSF49879 14 111 1.13E-15 T 11-11-2016 IPR008984 SMAD/FHA domain GO:0005515 AUP74_RS01455 ec3f773e2efb166ad49266dc04668f74 361 Gene3D G3DSA:2.60.200.20 12 112 1.7E-17 T 11-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 AUP74_RS01455 ec3f773e2efb166ad49266dc04668f74 361 Pfam PF00498 FHA domain 26 98 6.8E-8 T 11-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 AUP74_RS02285 1098cbdd6656cb8b19804206e5ce3b02 386 SUPERFAMILY SSF55031 184 297 5.53E-21 T 11-11-2016 IPR011650 Peptidase M20, dimerisation domain AUP74_RS02285 1098cbdd6656cb8b19804206e5ce3b02 386 Gene3D G3DSA:3.40.630.10 8 192 7.7E-60 T 11-11-2016 AUP74_RS02285 1098cbdd6656cb8b19804206e5ce3b02 386 Gene3D G3DSA:3.40.630.10 326 385 7.7E-60 T 11-11-2016 AUP74_RS02285 1098cbdd6656cb8b19804206e5ce3b02 386 Hamap MF_01108 Acetylornithine deacetylase [argE]. 3 386 50.647 T 11-11-2016 IPR010169 Acetylornithine deacetylase ArgE GO:0005737|GO:0006526|GO:0008777 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154 AUP74_RS02285 1098cbdd6656cb8b19804206e5ce3b02 386 Pfam PF07687 Peptidase dimerisation domain 182 286 4.5E-21 T 11-11-2016 IPR011650 Peptidase M20, dimerisation domain AUP74_RS02285 1098cbdd6656cb8b19804206e5ce3b02 386 Pfam PF01546 Peptidase family M20/M25/M40 80 382 2.1E-30 T 11-11-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 AUP74_RS02285 1098cbdd6656cb8b19804206e5ce3b02 386 TIGRFAM TIGR01892 AcOrn-deacetyl: acetylornithine deacetylase (ArgE) 12 379 9.5E-114 T 11-11-2016 IPR010169 Acetylornithine deacetylase ArgE GO:0005737|GO:0006526|GO:0008777 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154 AUP74_RS02285 1098cbdd6656cb8b19804206e5ce3b02 386 Gene3D G3DSA:3.30.70.360 193 289 5.2E-23 T 11-11-2016 IPR011650 Peptidase M20, dimerisation domain AUP74_RS02285 1098cbdd6656cb8b19804206e5ce3b02 386 SUPERFAMILY SSF53187 308 385 2.86E-54 T 11-11-2016 AUP74_RS02285 1098cbdd6656cb8b19804206e5ce3b02 386 SUPERFAMILY SSF53187 5 183 2.86E-54 T 11-11-2016 AUP74_RS09925 d0987a53b013c31fde22358a429ccca0 306 SUPERFAMILY SSF46785 5 110 5.28E-16 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS09925 d0987a53b013c31fde22358a429ccca0 306 Gene3D G3DSA:1.10.10.10 6 84 1.2E-18 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS09925 d0987a53b013c31fde22358a429ccca0 306 Gene3D G3DSA:3.40.190.10 94 177 4.6E-13 T 11-11-2016 AUP74_RS09925 d0987a53b013c31fde22358a429ccca0 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 3.7E-13 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS09925 d0987a53b013c31fde22358a429ccca0 306 SUPERFAMILY SSF53850 95 296 3.48E-32 T 11-11-2016 AUP74_RS09925 d0987a53b013c31fde22358a429ccca0 306 Pfam PF03466 LysR substrate binding domain 94 290 4.3E-34 T 11-11-2016 IPR005119 LysR, substrate-binding AUP74_RS09925 d0987a53b013c31fde22358a429ccca0 306 Gene3D G3DSA:3.40.190.10 178 260 1.7E-21 T 11-11-2016 AUP74_RS08805 f9d85bf415351be4eae28b20c2fe4d42 575 Pfam PF02080 TrkA-C domain 295 350 1.5E-9 T 11-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AUP74_RS08805 f9d85bf415351be4eae28b20c2fe4d42 575 Pfam PF02080 TrkA-C domain 209 276 5.0E-9 T 11-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AUP74_RS08805 f9d85bf415351be4eae28b20c2fe4d42 575 Gene3D G3DSA:3.30.70.1450 291 350 2.2E-17 T 11-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AUP74_RS08805 f9d85bf415351be4eae28b20c2fe4d42 575 Gene3D G3DSA:3.30.70.1450 206 284 8.9E-16 T 11-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AUP74_RS08805 f9d85bf415351be4eae28b20c2fe4d42 575 SUPERFAMILY SSF116726 290 352 2.88E-14 T 11-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AUP74_RS08805 f9d85bf415351be4eae28b20c2fe4d42 575 SUPERFAMILY SSF116726 206 281 9.02E-15 T 11-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AUP74_RS08805 f9d85bf415351be4eae28b20c2fe4d42 575 Pfam PF03600 Citrate transporter 18 520 1.7E-33 T 11-11-2016 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 AUP74_RS14130 fa6b9d0073dd128047a8599c0ec68f10 394 Gene3D G3DSA:3.40.640.10 6 256 7.0E-99 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AUP74_RS14130 fa6b9d0073dd128047a8599c0ec68f10 394 Gene3D G3DSA:3.90.1150.10 258 393 4.4E-50 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS14130 fa6b9d0073dd128047a8599c0ec68f10 394 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 8 390 1.5E-144 T 11-11-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AUP74_RS14130 fa6b9d0073dd128047a8599c0ec68f10 394 PIRSF PIRSF001434 1 394 4.1E-146 T 11-11-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AUP74_RS14130 fa6b9d0073dd128047a8599c0ec68f10 394 SUPERFAMILY SSF53383 27 392 4.03E-120 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase AUP74_RS14130 fa6b9d0073dd128047a8599c0ec68f10 394 TIGRFAM TIGR01328 met_gam_lyase: methionine gamma-lyase 6 392 9.5E-168 T 11-11-2016 IPR006237 L-methionine gamma-lyase GO:0018826 KEGG: 00270+4.4.1.11|KEGG: 00450+4.4.1.11|KEGG: 00920+4.4.1.2 AUP74_RS14130 fa6b9d0073dd128047a8599c0ec68f10 394 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 200 214 - T 11-11-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AUP74_RS09085 90c48379219e45f6a4c06cf9af52eb49 642 SMART SM00086 222 264 8.0E-7 T 11-11-2016 IPR001610 PAC motif AUP74_RS09085 90c48379219e45f6a4c06cf9af52eb49 642 SMART SM00086 87 132 370.0 T 11-11-2016 IPR001610 PAC motif AUP74_RS09085 90c48379219e45f6a4c06cf9af52eb49 642 Pfam PF00512 His Kinase A (phospho-acceptor) domain 291 349 2.0E-13 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS09085 90c48379219e45f6a4c06cf9af52eb49 642 Pfam PF08447 PAS fold 189 257 3.1E-13 T 11-11-2016 IPR013655 PAS fold-3 GO:0005515 AUP74_RS09085 90c48379219e45f6a4c06cf9af52eb49 642 PRINTS PR00344 Bacterial sensor protein C-terminal signature 469 487 3.0E-15 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS09085 90c48379219e45f6a4c06cf9af52eb49 642 PRINTS PR00344 Bacterial sensor protein C-terminal signature 493 506 3.0E-15 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS09085 90c48379219e45f6a4c06cf9af52eb49 642 PRINTS PR00344 Bacterial sensor protein C-terminal signature 453 463 3.0E-15 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS09085 90c48379219e45f6a4c06cf9af52eb49 642 PRINTS PR00344 Bacterial sensor protein C-terminal signature 435 449 3.0E-15 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS09085 90c48379219e45f6a4c06cf9af52eb49 642 Gene3D G3DSA:3.30.450.20 145 262 2.0E-19 T 11-11-2016 AUP74_RS09085 90c48379219e45f6a4c06cf9af52eb49 642 Gene3D G3DSA:3.30.565.10 353 508 1.3E-39 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS09085 90c48379219e45f6a4c06cf9af52eb49 642 Gene3D G3DSA:3.40.50.2300 531 613 6.5E-7 T 11-11-2016 AUP74_RS09085 90c48379219e45f6a4c06cf9af52eb49 642 SMART SM00388 284 350 1.1E-13 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS09085 90c48379219e45f6a4c06cf9af52eb49 642 SUPERFAMILY SSF47384 271 351 8.04E-16 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS09085 90c48379219e45f6a4c06cf9af52eb49 642 SMART SM00387 397 509 6.4E-34 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS09085 90c48379219e45f6a4c06cf9af52eb49 642 SUPERFAMILY SSF55874 340 507 4.45E-40 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS09085 90c48379219e45f6a4c06cf9af52eb49 642 Gene3D G3DSA:1.10.287.130 276 346 6.0E-12 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS09085 90c48379219e45f6a4c06cf9af52eb49 642 SUPERFAMILY SSF52172 529 595 2.13E-8 T 11-11-2016 IPR011006 CheY-like superfamily AUP74_RS09085 90c48379219e45f6a4c06cf9af52eb49 642 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 398 506 5.2E-24 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS09085 90c48379219e45f6a4c06cf9af52eb49 642 SUPERFAMILY SSF55785 153 265 9.07E-17 T 11-11-2016 IPR000014 PAS domain AUP74_RS03100 47d317dd626cc03b6e1b5e3f542c6f3b 516 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 139 155 - T 11-11-2016 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 AUP74_RS03100 47d317dd626cc03b6e1b5e3f542c6f3b 516 SUPERFAMILY SSF48557 5 503 5.18E-191 T 11-11-2016 IPR008948 L-Aspartase-like GO:0003824 AUP74_RS03100 47d317dd626cc03b6e1b5e3f542c6f3b 516 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 3 509 44.248 T 11-11-2016 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AUP74_RS03100 47d317dd626cc03b6e1b5e3f542c6f3b 516 Gene3D G3DSA:1.20.200.10 198 502 2.5E-124 T 11-11-2016 AUP74_RS03100 47d317dd626cc03b6e1b5e3f542c6f3b 516 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 5 512 4.9E-211 T 11-11-2016 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AUP74_RS03100 47d317dd626cc03b6e1b5e3f542c6f3b 516 Gene3D G3DSA:1.10.275.10 4 197 2.2E-74 T 11-11-2016 IPR024083 Fumarase/histidase, N-terminal AUP74_RS03100 47d317dd626cc03b6e1b5e3f542c6f3b 516 Pfam PF00221 Aromatic amino acid lyase 11 475 3.1E-186 T 11-11-2016 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 AUP74_RS03950 ab8d9c859f820198de961a9aca0908e4 202 PIRSF PIRSF004553 20 197 7.1E-50 T 11-11-2016 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AUP74_RS03950 ab8d9c859f820198de961a9aca0908e4 202 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 17 194 2.5E-48 T 11-11-2016 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AUP74_RS03950 ab8d9c859f820198de961a9aca0908e4 202 Pfam PF03602 Conserved hypothetical protein 95 21 193 1.6E-52 T 11-11-2016 AUP74_RS03950 ab8d9c859f820198de961a9aca0908e4 202 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 133 139 - T 11-11-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 AUP74_RS03950 ab8d9c859f820198de961a9aca0908e4 202 Gene3D G3DSA:3.40.50.150 19 197 6.6E-60 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS03950 ab8d9c859f820198de961a9aca0908e4 202 SUPERFAMILY SSF53335 20 193 4.78E-49 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS12325 048ff603d3cecc50cda22766195e8cfc 498 SMART SM00382 251 377 0.0013 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS12325 048ff603d3cecc50cda22766195e8cfc 498 Pfam PF00437 Type II/IV secretion system protein 126 390 2.5E-87 T 11-11-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 AUP74_RS12325 048ff603d3cecc50cda22766195e8cfc 498 Gene3D G3DSA:3.30.450.90 98 223 5.7E-53 T 11-11-2016 AUP74_RS12325 048ff603d3cecc50cda22766195e8cfc 498 Gene3D G3DSA:3.40.50.300 229 496 6.8E-98 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS12325 048ff603d3cecc50cda22766195e8cfc 498 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 9 80 4.4E-5 T 11-11-2016 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 AUP74_RS12325 048ff603d3cecc50cda22766195e8cfc 498 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 318 332 - T 11-11-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 AUP74_RS12325 048ff603d3cecc50cda22766195e8cfc 498 SUPERFAMILY SSF52540 108 495 1.11E-99 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS12325 048ff603d3cecc50cda22766195e8cfc 498 TIGRFAM TIGR02533 type_II_gspE: type II secretion system protein E 12 495 3.2E-209 T 11-11-2016 IPR013369 Type II secretion system GspE GO:0005524|GO:0008565|GO:0015627|GO:0015628 AUP74_RS12325 048ff603d3cecc50cda22766195e8cfc 498 SUPERFAMILY SSF160246 13 77 1.24E-14 T 11-11-2016 AUP74_RS07345 3e1602bcd76c5e5ac86fda337e2a1bec 592 Gene3D G3DSA:3.40.350.10 3 115 1.0E-16 T 11-11-2016 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal AUP74_RS07345 3e1602bcd76c5e5ac86fda337e2a1bec 592 Pfam PF00557 Metallopeptidase family M24 310 526 5.9E-45 T 11-11-2016 IPR000994 Peptidase M24, structural domain AUP74_RS07345 3e1602bcd76c5e5ac86fda337e2a1bec 592 SUPERFAMILY SSF53092 3 129 4.88E-11 T 11-11-2016 IPR028980 Creatinase/Aminopeptidase P, N-terminal AUP74_RS07345 3e1602bcd76c5e5ac86fda337e2a1bec 592 Pfam PF01321 Creatinase/Prolidase N-terminal domain 5 130 5.0E-17 T 11-11-2016 IPR000587 Creatinase, N-terminal GO:0016787 AUP74_RS07345 3e1602bcd76c5e5ac86fda337e2a1bec 592 Pfam PF16189 Creatinase/Prolidase N-terminal domain 146 305 1.3E-31 T 11-11-2016 AUP74_RS07345 3e1602bcd76c5e5ac86fda337e2a1bec 592 Pfam PF16188 C-terminal region of peptidase_M24 533 592 1.2E-22 T 11-11-2016 IPR032416 Peptidase M24, C-terminal domain AUP74_RS07345 3e1602bcd76c5e5ac86fda337e2a1bec 592 Gene3D G3DSA:3.90.230.10 300 558 1.0E-57 T 11-11-2016 IPR000994 Peptidase M24, structural domain AUP74_RS07345 3e1602bcd76c5e5ac86fda337e2a1bec 592 SUPERFAMILY SSF55920 302 556 3.14E-55 T 11-11-2016 IPR000994 Peptidase M24, structural domain AUP74_RS02515 d7eb7c9cf8d384fc96bffc4b016da40c 720 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 323 501 1.2E-60 T 11-11-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 AUP74_RS02515 d7eb7c9cf8d384fc96bffc4b016da40c 720 Gene3D G3DSA:3.90.226.10 2 201 4.4E-53 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS02515 d7eb7c9cf8d384fc96bffc4b016da40c 720 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 200 1.9E-31 T 11-11-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 AUP74_RS02515 d7eb7c9cf8d384fc96bffc4b016da40c 720 SUPERFAMILY SSF48179 628 715 1.53E-18 T 11-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AUP74_RS02515 d7eb7c9cf8d384fc96bffc4b016da40c 720 Gene3D G3DSA:3.40.50.720 317 505 1.3E-57 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS02515 d7eb7c9cf8d384fc96bffc4b016da40c 720 SUPERFAMILY SSF52096 3 299 2.38E-61 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS02515 d7eb7c9cf8d384fc96bffc4b016da40c 720 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 504 603 4.1E-19 T 11-11-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 AUP74_RS02515 d7eb7c9cf8d384fc96bffc4b016da40c 720 Gene3D G3DSA:1.10.1040.10 506 603 6.2E-16 T 11-11-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AUP74_RS02515 d7eb7c9cf8d384fc96bffc4b016da40c 720 SUPERFAMILY SSF48179 503 642 3.4E-21 T 11-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AUP74_RS02515 d7eb7c9cf8d384fc96bffc4b016da40c 720 SUPERFAMILY SSF51735 320 502 3.38E-55 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS02515 d7eb7c9cf8d384fc96bffc4b016da40c 720 Gene3D G3DSA:1.10.1040.10 635 715 3.6E-12 T 11-11-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AUP74_RS09460 a1dae8955407ee45f53307f636ced07d 205 TIGRFAM TIGR00781 ccoO: cytochrome c oxidase, cbb3-type, subunit II 4 176 2.1E-81 T 11-11-2016 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO AUP74_RS09460 a1dae8955407ee45f53307f636ced07d 205 SUPERFAMILY SSF46626 14 197 3.21E-30 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS09460 a1dae8955407ee45f53307f636ced07d 205 Pfam PF02433 Cytochrome C oxidase, mono-heme subunit/FixO 4 177 8.1E-79 T 11-11-2016 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO AUP74_RS09460 a1dae8955407ee45f53307f636ced07d 205 Gene3D G3DSA:1.10.760.10 15 198 5.5E-33 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS12650 beb1d4ee7aca8306632a7195d5e6add5 804 SUPERFAMILY SSF52009 366 477 4.06E-28 T 11-11-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 AUP74_RS12650 beb1d4ee7aca8306632a7195d5e6add5 804 SUPERFAMILY SSF56059 5 391 2.24E-94 T 11-11-2016 AUP74_RS12650 beb1d4ee7aca8306632a7195d5e6add5 804 PIRSF PIRSF000854 2 804 0.0 T 11-11-2016 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 AUP74_RS12650 beb1d4ee7aca8306632a7195d5e6add5 804 Gene3D G3DSA:3.30.470.20 199 356 4.3E-49 T 11-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 AUP74_RS12650 beb1d4ee7aca8306632a7195d5e6add5 804 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 21 351 5.0E-105 T 11-11-2016 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 AUP74_RS12650 beb1d4ee7aca8306632a7195d5e6add5 804 Pfam PF00391 PEP-utilising enzyme, mobile domain 395 466 2.8E-22 T 11-11-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 AUP74_RS12650 beb1d4ee7aca8306632a7195d5e6add5 804 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 425 436 - T 11-11-2016 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 AUP74_RS12650 beb1d4ee7aca8306632a7195d5e6add5 804 Gene3D G3DSA:3.20.20.60 491 801 2.1E-96 T 11-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AUP74_RS12650 beb1d4ee7aca8306632a7195d5e6add5 804 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 8 802 0.0 T 11-11-2016 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 AUP74_RS12650 beb1d4ee7aca8306632a7195d5e6add5 804 Gene3D G3DSA:3.30.1490.20 6 196 3.3E-62 T 11-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 AUP74_RS12650 beb1d4ee7aca8306632a7195d5e6add5 804 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 490 800 3.3E-57 T 11-11-2016 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 AUP74_RS12650 beb1d4ee7aca8306632a7195d5e6add5 804 Gene3D G3DSA:3.50.30.10 386 482 4.9E-28 T 11-11-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 AUP74_RS12650 beb1d4ee7aca8306632a7195d5e6add5 804 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 706 724 - T 11-11-2016 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 AUP74_RS12650 beb1d4ee7aca8306632a7195d5e6add5 804 SUPERFAMILY SSF51621 473 802 1.51E-91 T 11-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AUP74_RS03035 49d8857443ba65768c807b249bd9ff16 782 Gene3D G3DSA:1.10.3500.10 109 327 5.5E-98 T 11-11-2016 IPR023323 Tex-like domain AUP74_RS03035 49d8857443ba65768c807b249bd9ff16 782 Gene3D G3DSA:1.10.3500.10 456 502 5.5E-98 T 11-11-2016 IPR023323 Tex-like domain AUP74_RS03035 49d8857443ba65768c807b249bd9ff16 782 SUPERFAMILY SSF47781 565 637 1.8E-19 T 11-11-2016 IPR010994 RuvA domain 2-like AUP74_RS03035 49d8857443ba65768c807b249bd9ff16 782 Gene3D G3DSA:2.40.50.140 641 727 7.0E-29 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS03035 49d8857443ba65768c807b249bd9ff16 782 Pfam PF12836 Helix-hairpin-helix motif 496 560 6.4E-25 T 11-11-2016 AUP74_RS03035 49d8857443ba65768c807b249bd9ff16 782 Pfam PF16921 Tex protein YqgF-like domain 331 456 7.0E-53 T 11-11-2016 IPR032639 Tex protein, YqgF-like domain AUP74_RS03035 49d8857443ba65768c807b249bd9ff16 782 SMART SM00732 331 429 4.7E-33 T 11-11-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 AUP74_RS03035 49d8857443ba65768c807b249bd9ff16 782 SUPERFAMILY SSF50249 642 729 1.04E-25 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS03035 49d8857443ba65768c807b249bd9ff16 782 SUPERFAMILY SSF47781 475 563 4.34E-26 T 11-11-2016 IPR010994 RuvA domain 2-like AUP74_RS03035 49d8857443ba65768c807b249bd9ff16 782 SUPERFAMILY SSF158832 1 326 3.01E-118 T 11-11-2016 AUP74_RS03035 49d8857443ba65768c807b249bd9ff16 782 SUPERFAMILY SSF53098 327 474 5.23E-50 T 11-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 AUP74_RS03035 49d8857443ba65768c807b249bd9ff16 782 SMART SM00316 654 725 8.7E-24 T 11-11-2016 IPR022967 RNA-binding domain, S1 AUP74_RS03035 49d8857443ba65768c807b249bd9ff16 782 Gene3D G3DSA:1.10.150.310 504 635 2.0E-46 T 11-11-2016 IPR023097 Tex RuvX-like domain AUP74_RS03035 49d8857443ba65768c807b249bd9ff16 782 Pfam PF00575 S1 RNA binding domain 654 725 3.2E-21 T 11-11-2016 IPR003029 S1 domain GO:0003676 AUP74_RS03035 49d8857443ba65768c807b249bd9ff16 782 Pfam PF09371 Tex-like protein N-terminal domain 8 197 3.3E-71 T 11-11-2016 IPR018974 Tex-like protein, N-terminal AUP74_RS03035 49d8857443ba65768c807b249bd9ff16 782 Gene3D G3DSA:3.30.420.140 331 455 1.7E-50 T 11-11-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 AUP74_RS03035 49d8857443ba65768c807b249bd9ff16 782 Gene3D G3DSA:1.10.10.650 3 108 7.1E-48 T 11-11-2016 IPR023319 Tex-like protein, HTH domain AUP74_RS02460 918b098ceebdea4c14f3748ffedbba2d 106 Pfam PF05164 Cell division protein ZapA 11 93 1.1E-22 T 11-11-2016 IPR007838 Cell division protein ZapA-like AUP74_RS02460 918b098ceebdea4c14f3748ffedbba2d 106 SUPERFAMILY SSF102829 10 95 7.45E-21 T 11-11-2016 IPR007838 Cell division protein ZapA-like AUP74_RS00285 28ccdf8cff1fe0129b0586d6dd7cc8f6 348 SUPERFAMILY SSF47413 2 60 6.22E-19 T 11-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AUP74_RS00285 28ccdf8cff1fe0129b0586d6dd7cc8f6 348 Gene3D G3DSA:1.10.260.40 3 54 5.2E-26 T 11-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AUP74_RS00285 28ccdf8cff1fe0129b0586d6dd7cc8f6 348 Pfam PF13377 Periplasmic binding protein-like domain 174 343 2.0E-30 T 11-11-2016 AUP74_RS00285 28ccdf8cff1fe0129b0586d6dd7cc8f6 348 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 1.0E-19 T 11-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AUP74_RS00285 28ccdf8cff1fe0129b0586d6dd7cc8f6 348 Gene3D G3DSA:3.40.50.2300 55 177 3.2E-29 T 11-11-2016 AUP74_RS00285 28ccdf8cff1fe0129b0586d6dd7cc8f6 348 SMART SM00354 2 72 1.4E-27 T 11-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AUP74_RS00285 28ccdf8cff1fe0129b0586d6dd7cc8f6 348 Gene3D G3DSA:3.40.50.2300 178 313 1.4E-48 T 11-11-2016 AUP74_RS00285 28ccdf8cff1fe0129b0586d6dd7cc8f6 348 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 11-11-2016 AUP74_RS00285 28ccdf8cff1fe0129b0586d6dd7cc8f6 348 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 2.0E-5 T 11-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AUP74_RS00285 28ccdf8cff1fe0129b0586d6dd7cc8f6 348 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 2.0E-5 T 11-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AUP74_RS00285 28ccdf8cff1fe0129b0586d6dd7cc8f6 348 SUPERFAMILY SSF53822 62 346 1.14E-63 T 11-11-2016 IPR028082 Periplasmic binding protein-like I AUP74_RS07705 5ee56f8f321f14d332c6b2effd2c21c3 229 SMART SM00900 105 197 1.4E-35 T 11-11-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 AUP74_RS07705 5ee56f8f321f14d332c6b2effd2c21c3 229 Hamap MF_00479 Electron transport complex subunit RsxG [rsxG]. 3 199 25.667 T 11-11-2016 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 AUP74_RS07705 5ee56f8f321f14d332c6b2effd2c21c3 229 PIRSF PIRSF006091 1 210 1.9E-67 T 11-11-2016 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 AUP74_RS07705 5ee56f8f321f14d332c6b2effd2c21c3 229 Pfam PF04205 FMN-binding domain 105 194 1.1E-20 T 11-11-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 AUP74_RS07705 5ee56f8f321f14d332c6b2effd2c21c3 229 TIGRFAM TIGR01947 rnfG: electron transport complex, RnfABCDGE type, G subunit 11 197 1.1E-55 T 11-11-2016 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 AUP74_RS08040 5849d0a55bce129d6458d1eea729fcd6 515 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 143 369 6.6E-73 T 11-11-2016 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain AUP74_RS08040 5849d0a55bce129d6458d1eea729fcd6 515 SMART SM01003 4 139 4.5E-68 T 11-11-2016 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal AUP74_RS08040 5849d0a55bce129d6458d1eea729fcd6 515 SUPERFAMILY SSF52283 2 170 8.5E-53 T 11-11-2016 AUP74_RS08040 5849d0a55bce129d6458d1eea729fcd6 515 SMART SM01002 148 312 9.2E-85 T 11-11-2016 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain AUP74_RS08040 5849d0a55bce129d6458d1eea729fcd6 515 Gene3D G3DSA:3.40.50.1770 3 189 7.1E-69 T 11-11-2016 AUP74_RS08040 5849d0a55bce129d6458d1eea729fcd6 515 ProSitePatterns PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1. 4 30 - T 11-11-2016 IPR008142 Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 GO:0016491|GO:0055114 Reactome: R-HSA-71403 AUP74_RS08040 5849d0a55bce129d6458d1eea729fcd6 515 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 431 515 3.1E-35 T 11-11-2016 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 AUP74_RS08040 5849d0a55bce129d6458d1eea729fcd6 515 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 172 197 - T 11-11-2016 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 AUP74_RS08040 5849d0a55bce129d6458d1eea729fcd6 515 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 5 139 1.1E-47 T 11-11-2016 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal AUP74_RS08040 5849d0a55bce129d6458d1eea729fcd6 515 TIGRFAM TIGR00561 pntA: NAD(P)(+) transhydrogenase (AB-specific), alpha subunit 3 515 1.8E-230 T 11-11-2016 IPR026255 NAD(P) transhydrogenase, alpha subunit GO:0008746|GO:0015992|GO:0055114 KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 AUP74_RS08040 5849d0a55bce129d6458d1eea729fcd6 515 Gene3D G3DSA:3.40.50.1770 190 372 1.4E-47 T 11-11-2016 AUP74_RS08040 5849d0a55bce129d6458d1eea729fcd6 515 SUPERFAMILY SSF51735 139 318 2.73E-39 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS08040 5849d0a55bce129d6458d1eea729fcd6 515 PIRSF PIRSF000203 1 515 2.3E-245 T 11-11-2016 IPR026255 NAD(P) transhydrogenase, alpha subunit GO:0008746|GO:0015992|GO:0055114 KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 AUP74_RS08545 fb1f9129e3802b78171bc832bc6846ea 705 SUPERFAMILY SSF49899 14 257 2.49E-66 T 11-11-2016 IPR013320 Concanavalin A-like lectin/glucanase domain AUP74_RS08545 fb1f9129e3802b78171bc832bc6846ea 705 Pfam PF00801 PKD domain 522 589 7.0E-14 T 11-11-2016 IPR000601 PKD domain AUP74_RS08545 fb1f9129e3802b78171bc832bc6846ea 705 SUPERFAMILY SSF49299 517 599 8.37E-23 T 11-11-2016 IPR000601 PKD domain AUP74_RS08545 fb1f9129e3802b78171bc832bc6846ea 705 SUPERFAMILY SSF49373 612 689 5.1E-6 T 11-11-2016 IPR008964 Invasin/intimin cell-adhesion fragments AUP74_RS08545 fb1f9129e3802b78171bc832bc6846ea 705 SMART SM00089 517 600 1.2E-21 T 11-11-2016 IPR022409 PKD/Chitinase domain AUP74_RS08545 fb1f9129e3802b78171bc832bc6846ea 705 Gene3D G3DSA:2.60.40.670 522 598 2.6E-21 T 11-11-2016 IPR000601 PKD domain AUP74_RS08545 fb1f9129e3802b78171bc832bc6846ea 705 Pfam PF00722 Glycosyl hydrolases family 16 56 253 9.6E-30 T 11-11-2016 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 AUP74_RS08545 fb1f9129e3802b78171bc832bc6846ea 705 Gene3D G3DSA:2.60.120.200 11 256 4.9E-75 T 11-11-2016 IPR013320 Concanavalin A-like lectin/glucanase domain AUP74_RS14810 c7a92af4a5f95568b4d728ff88050ed8 367 SMART SM00830 16 97 1.5E-31 T 11-11-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AUP74_RS14810 c7a92af4a5f95568b4d728ff88050ed8 367 PIRSF PIRSF001500 5 367 7.5E-143 T 11-11-2016 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 AUP74_RS14810 c7a92af4a5f95568b4d728ff88050ed8 367 SUPERFAMILY SSF48600 11 101 5.86E-21 T 11-11-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AUP74_RS14810 c7a92af4a5f95568b4d728ff88050ed8 367 Gene3D G3DSA:3.40.190.10 183 262 3.5E-30 T 11-11-2016 AUP74_RS14810 c7a92af4a5f95568b4d728ff88050ed8 367 SUPERFAMILY SSF55021 269 364 4.93E-27 T 11-11-2016 AUP74_RS14810 c7a92af4a5f95568b4d728ff88050ed8 367 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 312 319 - T 11-11-2016 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 AUP74_RS14810 c7a92af4a5f95568b4d728ff88050ed8 367 TIGRFAM TIGR01807 CM_P2: chorismate mutase 12 87 1.2E-29 T 11-11-2016 IPR010957 Gamma/beta/epsilon proteobacterial P-protein, chorismate mutase domain GO:0004106|GO:0005737|GO:0009094 KEGG: 00400+5.4.99.5+4.2.1.51|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7432|MetaCyc: PWY-7626 AUP74_RS14810 c7a92af4a5f95568b4d728ff88050ed8 367 Gene3D G3DSA:3.40.190.10 95 182 1.0E-31 T 11-11-2016 AUP74_RS14810 c7a92af4a5f95568b4d728ff88050ed8 367 Gene3D G3DSA:3.30.70.260 279 364 8.3E-30 T 11-11-2016 AUP74_RS14810 c7a92af4a5f95568b4d728ff88050ed8 367 Pfam PF01842 ACT domain 285 350 7.0E-11 T 11-11-2016 IPR002912 ACT domain GO:0008152|GO:0016597 AUP74_RS14810 c7a92af4a5f95568b4d728ff88050ed8 367 Pfam PF01817 Chorismate mutase type II 16 95 1.6E-23 T 11-11-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AUP74_RS14810 c7a92af4a5f95568b4d728ff88050ed8 367 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 250 272 - T 11-11-2016 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 AUP74_RS14810 c7a92af4a5f95568b4d728ff88050ed8 367 Gene3D G3DSA:1.20.59.10 6 94 5.6E-24 T 11-11-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AUP74_RS14810 c7a92af4a5f95568b4d728ff88050ed8 367 SUPERFAMILY SSF53850 98 283 2.82E-61 T 11-11-2016 AUP74_RS14810 c7a92af4a5f95568b4d728ff88050ed8 367 Pfam PF00800 Prephenate dehydratase 99 275 1.3E-63 T 11-11-2016 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 AUP74_RS14920 2ecae0f143711696038b25dfeef7b728 369 Gene3D G3DSA:1.50.10.20 12 140 7.4E-11 T 11-11-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid AUP74_RS14920 2ecae0f143711696038b25dfeef7b728 369 Gene3D G3DSA:1.50.10.20 256 300 7.4E-11 T 11-11-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid AUP74_RS14920 2ecae0f143711696038b25dfeef7b728 369 SUPERFAMILY SSF48208 32 330 1.7E-38 T 11-11-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 AUP74_RS12340 9780e02bdbf6294483871f4bf65f08f2 190 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 9 31 2.0E-9 T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS12340 9780e02bdbf6294483871f4bf65f08f2 190 Pfam PF13633 Prokaryotic N-terminal methylation site 9 31 1.5E-9 T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS12340 9780e02bdbf6294483871f4bf65f08f2 190 PRINTS PR00885 Bacterial general secretion pathway protein H signature 6 20 9.1E-11 T 11-11-2016 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 AUP74_RS12340 9780e02bdbf6294483871f4bf65f08f2 190 PRINTS PR00885 Bacterial general secretion pathway protein H signature 142 157 9.1E-11 T 11-11-2016 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 AUP74_RS12340 9780e02bdbf6294483871f4bf65f08f2 190 PRINTS PR00885 Bacterial general secretion pathway protein H signature 21 35 9.1E-11 T 11-11-2016 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 AUP74_RS12340 9780e02bdbf6294483871f4bf65f08f2 190 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 9 29 - T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS12340 9780e02bdbf6294483871f4bf65f08f2 190 SUPERFAMILY SSF54523 11 79 1.65E-14 T 11-11-2016 AUP74_RS12340 9780e02bdbf6294483871f4bf65f08f2 190 Gene3D G3DSA:3.55.40.10 57 178 7.6E-15 T 11-11-2016 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 AUP74_RS12340 9780e02bdbf6294483871f4bf65f08f2 190 Gene3D G3DSA:3.30.700.10 11 56 1.0E-5 T 11-11-2016 AUP74_RS00605 b088ae66f8da4f4d6bed1c24e4478e45 148 PIRSF PIRSF006173 1 147 5.5E-65 T 11-11-2016 IPR008228 Uncharacterised conserved protein UCP006173 AUP74_RS00605 b088ae66f8da4f4d6bed1c24e4478e45 148 Pfam PF03692 Putative zinc- or iron-chelating domain 24 92 2.4E-6 T 11-11-2016 IPR005358 Putative zinc- or iron-chelating domain containing protein AUP74_RS00605 b088ae66f8da4f4d6bed1c24e4478e45 148 Hamap MF_00676 UPF0260 protein YcgN [ycgN]. 2 147 40.91 T 11-11-2016 IPR008228 Uncharacterised conserved protein UCP006173 AUP74_RS09585 4cf42d5d048d1b161294209822916d7d 546 Gene3D G3DSA:1.10.560.10 369 517 1.0E-40 T 11-11-2016 IPR027413 GroEL-like equatorial domain AUP74_RS09585 4cf42d5d048d1b161294209822916d7d 546 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 11-11-2016 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020 AUP74_RS09585 4cf42d5d048d1b161294209822916d7d 546 Gene3D G3DSA:3.50.7.10 189 368 1.5E-100 T 11-11-2016 IPR027409 GroEL-like apical domain AUP74_RS09585 4cf42d5d048d1b161294209822916d7d 546 Gene3D G3DSA:1.10.560.10 3 188 2.9E-47 T 11-11-2016 IPR027413 GroEL-like equatorial domain AUP74_RS09585 4cf42d5d048d1b161294209822916d7d 546 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 523 1.6E-95 T 11-11-2016 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 AUP74_RS09585 4cf42d5d048d1b161294209822916d7d 546 SUPERFAMILY SSF52029 185 376 2.97E-85 T 11-11-2016 IPR027409 GroEL-like apical domain AUP74_RS09585 4cf42d5d048d1b161294209822916d7d 546 PRINTS PR00298 60kDa chaperonin signature 27 53 8.2E-75 T 11-11-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 AUP74_RS09585 4cf42d5d048d1b161294209822916d7d 546 PRINTS PR00298 60kDa chaperonin signature 350 375 8.2E-75 T 11-11-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 AUP74_RS09585 4cf42d5d048d1b161294209822916d7d 546 PRINTS PR00298 60kDa chaperonin signature 398 419 8.2E-75 T 11-11-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 AUP74_RS09585 4cf42d5d048d1b161294209822916d7d 546 PRINTS PR00298 60kDa chaperonin signature 83 110 8.2E-75 T 11-11-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 AUP74_RS09585 4cf42d5d048d1b161294209822916d7d 546 PRINTS PR00298 60kDa chaperonin signature 268 291 8.2E-75 T 11-11-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 AUP74_RS09585 4cf42d5d048d1b161294209822916d7d 546 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 526 1.6E-256 T 11-11-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 AUP74_RS09585 4cf42d5d048d1b161294209822916d7d 546 Hamap MF_00600 60 kDa chaperonin [groL]. 2 545 41.823 T 11-11-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 AUP74_RS09585 4cf42d5d048d1b161294209822916d7d 546 SUPERFAMILY SSF48592 406 520 2.14E-76 T 11-11-2016 AUP74_RS09585 4cf42d5d048d1b161294209822916d7d 546 SUPERFAMILY SSF48592 7 134 2.14E-76 T 11-11-2016 AUP74_RS09585 4cf42d5d048d1b161294209822916d7d 546 SUPERFAMILY SSF54849 137 204 6.64E-25 T 11-11-2016 AUP74_RS15035 694b065a5a9ab8a67d4370a1b376eccd 940 SUPERFAMILY SSF63411 735 928 1.69E-29 T 11-11-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AUP74_RS15035 694b065a5a9ab8a67d4370a1b376eccd 940 SUPERFAMILY SSF63411 291 473 5.17E-31 T 11-11-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AUP74_RS15035 694b065a5a9ab8a67d4370a1b376eccd 940 SUPERFAMILY SSF63411 502 719 6.33E-45 T 11-11-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AUP74_RS15035 694b065a5a9ab8a67d4370a1b376eccd 940 Gene3D G3DSA:3.30.830.10 63 281 8.0E-53 T 11-11-2016 IPR011237 Peptidase M16 domain GO:0046872 AUP74_RS15035 694b065a5a9ab8a67d4370a1b376eccd 940 Gene3D G3DSA:3.30.830.10 734 919 4.9E-18 T 11-11-2016 IPR011237 Peptidase M16 domain GO:0046872 AUP74_RS15035 694b065a5a9ab8a67d4370a1b376eccd 940 Gene3D G3DSA:3.30.830.10 298 473 1.0E-18 T 11-11-2016 IPR011237 Peptidase M16 domain GO:0046872 AUP74_RS15035 694b065a5a9ab8a67d4370a1b376eccd 940 Pfam PF05193 Peptidase M16 inactive domain 231 405 4.9E-30 T 11-11-2016 IPR007863 Peptidase M16, C-terminal AUP74_RS15035 694b065a5a9ab8a67d4370a1b376eccd 940 Pfam PF05193 Peptidase M16 inactive domain 671 848 1.7E-25 T 11-11-2016 IPR007863 Peptidase M16, C-terminal AUP74_RS15035 694b065a5a9ab8a67d4370a1b376eccd 940 Pfam PF00675 Insulinase (Peptidase family M16) 74 193 2.2E-15 T 11-11-2016 IPR011765 Peptidase M16, N-terminal AUP74_RS15035 694b065a5a9ab8a67d4370a1b376eccd 940 Pfam PF00675 Insulinase (Peptidase family M16) 515 633 1.4E-8 T 11-11-2016 IPR011765 Peptidase M16, N-terminal AUP74_RS15035 694b065a5a9ab8a67d4370a1b376eccd 940 Gene3D G3DSA:3.30.830.10 505 716 2.1E-42 T 11-11-2016 IPR011237 Peptidase M16 domain GO:0046872 AUP74_RS15035 694b065a5a9ab8a67d4370a1b376eccd 940 SUPERFAMILY SSF63411 62 280 1.76E-53 T 11-11-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AUP74_RS05805 ce054ee6b88c361ee42c7cf5038367dd 493 Pfam PF03853 YjeF-related protein N-terminus 30 189 2.4E-40 T 11-11-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 AUP74_RS05805 ce054ee6b88c361ee42c7cf5038367dd 493 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 9 211 23.321 T 11-11-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 AUP74_RS05805 ce054ee6b88c361ee42c7cf5038367dd 493 Pfam PF01256 Carbohydrate kinase 248 485 1.1E-56 T 11-11-2016 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 AUP74_RS05805 ce054ee6b88c361ee42c7cf5038367dd 493 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 232 491 1.2E-60 T 11-11-2016 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 AUP74_RS05805 ce054ee6b88c361ee42c7cf5038367dd 493 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 9 211 1.6E-45 T 11-11-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 AUP74_RS05805 ce054ee6b88c361ee42c7cf5038367dd 493 Gene3D G3DSA:3.40.50.10260 6 237 3.4E-64 T 11-11-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 AUP74_RS05805 ce054ee6b88c361ee42c7cf5038367dd 493 PIRSF PIRSF017184 5 493 8.5E-127 T 11-11-2016 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 AUP74_RS05805 ce054ee6b88c361ee42c7cf5038367dd 493 SUPERFAMILY SSF53613 230 491 3.71E-69 T 11-11-2016 IPR029056 Ribokinase-like AUP74_RS05805 ce054ee6b88c361ee42c7cf5038367dd 493 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 225 493 20.977 T 11-11-2016 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 AUP74_RS05805 ce054ee6b88c361ee42c7cf5038367dd 493 SUPERFAMILY SSF64153 6 247 3.4E-57 T 11-11-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 AUP74_RS05805 ce054ee6b88c361ee42c7cf5038367dd 493 Gene3D G3DSA:3.40.1190.20 238 491 4.3E-80 T 11-11-2016 IPR029056 Ribokinase-like AUP74_RS04915 14ea8bb871a67e7f3edee6d7bdfbd959 340 PIRSF PIRSF002849 1 339 1.5E-123 T 11-11-2016 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted AUP74_RS04915 14ea8bb871a67e7f3edee6d7bdfbd959 340 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 50 184 1.2E-62 T 11-11-2016 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 AUP74_RS04915 14ea8bb871a67e7f3edee6d7bdfbd959 340 Gene3D G3DSA:1.10.8.300 216 332 2.2E-33 T 11-11-2016 AUP74_RS04915 14ea8bb871a67e7f3edee6d7bdfbd959 340 SUPERFAMILY SSF52540 15 310 4.86E-46 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04915 14ea8bb871a67e7f3edee6d7bdfbd959 340 Gene3D G3DSA:3.40.50.300 32 200 3.0E-43 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS16385 0ae6194d7abfc2e7f093436f320595f1 485 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 45 435 9.8E-77 T 11-11-2016 IPR017439 Amidohydrolase GO:0016787 AUP74_RS16385 0ae6194d7abfc2e7f093436f320595f1 485 Gene3D G3DSA:3.40.630.10 322 354 3.5E-63 T 11-11-2016 AUP74_RS16385 0ae6194d7abfc2e7f093436f320595f1 485 Gene3D G3DSA:3.40.630.10 28 213 3.5E-63 T 11-11-2016 AUP74_RS16385 0ae6194d7abfc2e7f093436f320595f1 485 Gene3D G3DSA:3.40.630.10 386 462 3.5E-63 T 11-11-2016 AUP74_RS16385 0ae6194d7abfc2e7f093436f320595f1 485 SUPERFAMILY SSF55031 215 321 3.66E-22 T 11-11-2016 IPR011650 Peptidase M20, dimerisation domain AUP74_RS16385 0ae6194d7abfc2e7f093436f320595f1 485 SUPERFAMILY SSF53187 386 451 2.95E-56 T 11-11-2016 AUP74_RS16385 0ae6194d7abfc2e7f093436f320595f1 485 SUPERFAMILY SSF53187 34 226 2.95E-56 T 11-11-2016 AUP74_RS16385 0ae6194d7abfc2e7f093436f320595f1 485 SUPERFAMILY SSF53187 325 354 2.95E-56 T 11-11-2016 AUP74_RS16385 0ae6194d7abfc2e7f093436f320595f1 485 Pfam PF07687 Peptidase dimerisation domain 214 307 6.9E-10 T 11-11-2016 IPR011650 Peptidase M20, dimerisation domain AUP74_RS16385 0ae6194d7abfc2e7f093436f320595f1 485 Gene3D G3DSA:3.30.70.360 215 319 2.4E-24 T 11-11-2016 IPR011650 Peptidase M20, dimerisation domain AUP74_RS16385 0ae6194d7abfc2e7f093436f320595f1 485 PIRSF PIRSF037227 27 485 2.3E-162 T 11-11-2016 IPR017145 Aminobenzoyl-glutamate utilization protein B AUP74_RS16385 0ae6194d7abfc2e7f093436f320595f1 485 Pfam PF01546 Peptidase family M20/M25/M40 106 311 6.4E-7 T 11-11-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 AUP74_RS10450 3f617cd1ba54ee35f314425d2ce4e35e 515 Gene3D G3DSA:3.40.605.10 19 275 8.9E-89 T 11-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AUP74_RS10450 3f617cd1ba54ee35f314425d2ce4e35e 515 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 23 498 3.6E-201 T 11-11-2016 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 AUP74_RS10450 3f617cd1ba54ee35f314425d2ce4e35e 515 Pfam PF00171 Aldehyde dehydrogenase family 34 494 2.0E-136 T 11-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 AUP74_RS10450 3f617cd1ba54ee35f314425d2ce4e35e 515 Gene3D G3DSA:3.40.309.10 276 467 8.5E-64 T 11-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 AUP74_RS10450 3f617cd1ba54ee35f314425d2ce4e35e 515 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 290 301 - T 11-11-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 AUP74_RS10450 3f617cd1ba54ee35f314425d2ce4e35e 515 SUPERFAMILY SSF53720 12 499 1.2E-147 T 11-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AUP74_RS16755 fbf465f12e0bb7dc62619c89d392ab3c 461 Gene3D G3DSA:3.40.1190.10 83 311 5.5E-64 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AUP74_RS16755 fbf465f12e0bb7dc62619c89d392ab3c 461 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 5 452 30.986 T 11-11-2016 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AUP74_RS16755 fbf465f12e0bb7dc62619c89d392ab3c 461 Pfam PF08245 Mur ligase middle domain 106 295 5.8E-42 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AUP74_RS16755 fbf465f12e0bb7dc62619c89d392ab3c 461 Gene3D G3DSA:3.40.1390.10 4 81 1.1E-14 T 11-11-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 AUP74_RS16755 fbf465f12e0bb7dc62619c89d392ab3c 461 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 30 451 2.4E-126 T 11-11-2016 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AUP74_RS16755 fbf465f12e0bb7dc62619c89d392ab3c 461 Gene3D G3DSA:3.90.190.20 315 454 3.4E-43 T 11-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AUP74_RS16755 fbf465f12e0bb7dc62619c89d392ab3c 461 SUPERFAMILY SSF53623 102 311 4.71E-51 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AUP74_RS16755 fbf465f12e0bb7dc62619c89d392ab3c 461 Pfam PF02875 Mur ligase family, glutamate ligase domain 315 391 1.3E-13 T 11-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AUP74_RS16755 fbf465f12e0bb7dc62619c89d392ab3c 461 SUPERFAMILY SSF63418 4 98 3.92E-15 T 11-11-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 AUP74_RS16755 fbf465f12e0bb7dc62619c89d392ab3c 461 SUPERFAMILY SSF53244 315 451 2.38E-37 T 11-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AUP74_RS12160 97a49fb9e3c2dc4d66352866c2991342 398 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 14 397 1.1E-187 T 11-11-2016 IPR005862 Phosphoribosylglycinamide formyltransferase 2 GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 AUP74_RS12160 97a49fb9e3c2dc4d66352866c2991342 398 SUPERFAMILY SSF52440 4 112 2.88E-34 T 11-11-2016 IPR016185 Pre-ATP-grasp domain AUP74_RS12160 97a49fb9e3c2dc4d66352866c2991342 398 Hamap MF_01643 Phosphoribosylglycinamide formyltransferase 2 [purT]. 8 397 52.485 T 11-11-2016 IPR005862 Phosphoribosylglycinamide formyltransferase 2 GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 AUP74_RS12160 97a49fb9e3c2dc4d66352866c2991342 398 Pfam PF02222 ATP-grasp domain 123 300 4.1E-54 T 11-11-2016 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type AUP74_RS12160 97a49fb9e3c2dc4d66352866c2991342 398 Gene3D G3DSA:3.40.50.20 5 120 5.3E-40 T 11-11-2016 IPR016185 Pre-ATP-grasp domain AUP74_RS12160 97a49fb9e3c2dc4d66352866c2991342 398 Gene3D G3DSA:3.30.1490.20 123 198 1.3E-26 T 11-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 AUP74_RS12160 97a49fb9e3c2dc4d66352866c2991342 398 Pfam PF01370 NAD dependent epimerase/dehydratase family 19 81 2.7E-5 T 11-11-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 AUP74_RS12160 97a49fb9e3c2dc4d66352866c2991342 398 Gene3D G3DSA:3.30.470.20 199 391 5.9E-69 T 11-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 AUP74_RS12160 97a49fb9e3c2dc4d66352866c2991342 398 SUPERFAMILY SSF51246 326 395 2.04E-14 T 11-11-2016 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AUP74_RS12160 97a49fb9e3c2dc4d66352866c2991342 398 SUPERFAMILY SSF56059 113 321 7.95E-57 T 11-11-2016 AUP74_RS11925 acd5fccac8a2b56864341e7bf59a1c15 260 PIRSF PIRSF009437 1 260 3.4E-92 T 11-11-2016 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0055114 AUP74_RS11925 acd5fccac8a2b56864341e7bf59a1c15 260 SMART SM00900 145 246 1.1E-28 T 11-11-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 AUP74_RS11925 acd5fccac8a2b56864341e7bf59a1c15 260 TIGRFAM TIGR01938 nqrC: NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit 4 254 2.0E-81 T 11-11-2016 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0055114 AUP74_RS11925 acd5fccac8a2b56864341e7bf59a1c15 260 Hamap MF_00427 Na(+)-translocating NADH-quinone reductase subunit C [nqrC]. 5 260 35.201 T 11-11-2016 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0055114 AUP74_RS11925 acd5fccac8a2b56864341e7bf59a1c15 260 Pfam PF04205 FMN-binding domain 145 243 8.0E-16 T 11-11-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 AUP74_RS08065 82b2996dfd10d9b64a8bd369bacf4b34 207 PIRSF PIRSF005461 1 207 6.5E-80 T 11-11-2016 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 AUP74_RS08065 82b2996dfd10d9b64a8bd369bacf4b34 207 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 8 204 30.526 T 11-11-2016 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 AUP74_RS08065 82b2996dfd10d9b64a8bd369bacf4b34 207 Pfam PF01728 FtsJ-like methyltransferase 28 204 4.7E-59 T 11-11-2016 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 AUP74_RS08065 82b2996dfd10d9b64a8bd369bacf4b34 207 Gene3D G3DSA:3.40.50.150 3 206 2.2E-72 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS08065 82b2996dfd10d9b64a8bd369bacf4b34 207 SUPERFAMILY SSF53335 27 206 5.47E-46 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS12545 5bb72c40fd2f7778557d63b2f9b342a1 477 Gene3D G3DSA:3.40.309.10 264 446 1.8E-57 T 11-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 AUP74_RS12545 5bb72c40fd2f7778557d63b2f9b342a1 477 SUPERFAMILY SSF53720 4 474 1.31E-133 T 11-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AUP74_RS12545 5bb72c40fd2f7778557d63b2f9b342a1 477 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 248 255 - T 11-11-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 AUP74_RS12545 5bb72c40fd2f7778557d63b2f9b342a1 477 Gene3D G3DSA:3.40.605.10 5 263 1.7E-74 T 11-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AUP74_RS12545 5bb72c40fd2f7778557d63b2f9b342a1 477 Pfam PF00171 Aldehyde dehydrogenase family 21 467 2.8E-137 T 11-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 AUP74_RS03200 c549b1a5c522cacf6d6b5fad41eb9a1c 130 SMART SM00450 30 126 6.1E-21 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS03200 c549b1a5c522cacf6d6b5fad41eb9a1c 130 SUPERFAMILY SSF52821 5 129 4.85E-30 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS03200 c549b1a5c522cacf6d6b5fad41eb9a1c 130 Pfam PF00581 Rhodanese-like domain 32 122 2.4E-15 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS03200 c549b1a5c522cacf6d6b5fad41eb9a1c 130 Gene3D G3DSA:3.40.250.10 12 130 2.8E-26 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS04445 e9e6393083a036a6115aa4dbfd0cfd7d 629 Pfam PF13932 GidA associated domain 403 613 4.0E-72 T 11-11-2016 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 AUP74_RS04445 e9e6393083a036a6115aa4dbfd0cfd7d 629 Gene3D G3DSA:3.50.50.60 6 233 8.0E-49 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS04445 e9e6393083a036a6115aa4dbfd0cfd7d 629 SUPERFAMILY SSF51905 97 261 3.09E-49 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS04445 e9e6393083a036a6115aa4dbfd0cfd7d 629 SUPERFAMILY SSF51905 5 66 3.09E-49 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS04445 e9e6393083a036a6115aa4dbfd0cfd7d 629 SMART SM01228 544 615 1.5E-41 T 11-11-2016 AUP74_RS04445 e9e6393083a036a6115aa4dbfd0cfd7d 629 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 5 622 42.077 T 11-11-2016 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 AUP74_RS04445 e9e6393083a036a6115aa4dbfd0cfd7d 629 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 273 287 - T 11-11-2016 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 AUP74_RS04445 e9e6393083a036a6115aa4dbfd0cfd7d 629 Pfam PF01134 Glucose inhibited division protein A 8 398 2.7E-163 T 11-11-2016 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 AUP74_RS04445 e9e6393083a036a6115aa4dbfd0cfd7d 629 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 7 620 1.8E-275 T 11-11-2016 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 AUP74_RS04445 e9e6393083a036a6115aa4dbfd0cfd7d 629 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 368 391 - T 11-11-2016 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 AUP74_RS00645 8bcbc7bf935062b03001fa5fdad2cac7 916 Gene3D G3DSA:2.40.170.20 491 915 5.7E-82 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS00645 8bcbc7bf935062b03001fa5fdad2cac7 916 Gene3D G3DSA:2.40.170.20 206 265 5.7E-82 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS00645 8bcbc7bf935062b03001fa5fdad2cac7 916 Gene3D G3DSA:2.40.170.20 307 458 5.7E-82 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS00645 8bcbc7bf935062b03001fa5fdad2cac7 916 Pfam PF00593 TonB dependent receptor 592 907 7.0E-32 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS00645 8bcbc7bf935062b03001fa5fdad2cac7 916 Pfam PF07715 TonB-dependent Receptor Plug Domain 92 202 3.2E-23 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS00645 8bcbc7bf935062b03001fa5fdad2cac7 916 Gene3D G3DSA:2.170.130.10 91 205 3.7E-36 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS00645 8bcbc7bf935062b03001fa5fdad2cac7 916 SUPERFAMILY SSF56935 71 267 7.02E-96 T 11-11-2016 AUP74_RS00645 8bcbc7bf935062b03001fa5fdad2cac7 916 SUPERFAMILY SSF56935 400 460 7.02E-96 T 11-11-2016 AUP74_RS00645 8bcbc7bf935062b03001fa5fdad2cac7 916 SUPERFAMILY SSF56935 492 915 7.02E-96 T 11-11-2016 AUP74_RS00645 8bcbc7bf935062b03001fa5fdad2cac7 916 SUPERFAMILY SSF56935 325 373 7.02E-96 T 11-11-2016 AUP74_RS07030 77d7abe357e03d3058e3b728df6609ad 103 SUPERFAMILY SSF141091 1 101 8.63E-40 T 11-11-2016 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS07030 77d7abe357e03d3058e3b728df6609ad 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 101 4.1E-41 T 11-11-2016 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS07030 77d7abe357e03d3058e3b728df6609ad 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 11-11-2016 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS07030 77d7abe357e03d3058e3b728df6609ad 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 1.2E-43 T 11-11-2016 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS07030 77d7abe357e03d3058e3b728df6609ad 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 27.834 T 11-11-2016 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS02190 9e74b78bebb854591075872a8d7fbc47 495 Pfam PF02321 Outer membrane efflux protein 265 460 2.7E-33 T 11-11-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 AUP74_RS02190 9e74b78bebb854591075872a8d7fbc47 495 Pfam PF02321 Outer membrane efflux protein 45 230 1.3E-22 T 11-11-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 AUP74_RS02190 9e74b78bebb854591075872a8d7fbc47 495 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 35 474 1.0E-95 T 11-11-2016 IPR010130 Type I secretion outer membrane protein, TolC GO:0006810|GO:0019867 AUP74_RS02190 9e74b78bebb854591075872a8d7fbc47 495 Gene3D G3DSA:1.20.1600.10 33 463 2.8E-72 T 11-11-2016 AUP74_RS02190 9e74b78bebb854591075872a8d7fbc47 495 SUPERFAMILY SSF56954 13 463 1.11E-81 T 11-11-2016 AUP74_RS09565 53a61f3884127ea857e0923d02752930 253 SUPERFAMILY SSF51735 1 252 4.27E-70 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS09565 53a61f3884127ea857e0923d02752930 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 2.0E-33 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS09565 53a61f3884127ea857e0923d02752930 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 2.0E-33 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS09565 53a61f3884127ea857e0923d02752930 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 2.0E-33 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS09565 53a61f3884127ea857e0923d02752930 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.0E-33 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS09565 53a61f3884127ea857e0923d02752930 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 2.0E-33 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS09565 53a61f3884127ea857e0923d02752930 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.0E-33 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS09565 53a61f3884127ea857e0923d02752930 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 11-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AUP74_RS09565 53a61f3884127ea857e0923d02752930 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 1.9E-10 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS09565 53a61f3884127ea857e0923d02752930 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.9E-10 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS09565 53a61f3884127ea857e0923d02752930 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 1.9E-10 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS09565 53a61f3884127ea857e0923d02752930 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 251 1.6E-56 T 11-11-2016 AUP74_RS09565 53a61f3884127ea857e0923d02752930 253 Gene3D G3DSA:3.40.50.720 2 251 2.8E-77 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS09565 53a61f3884127ea857e0923d02752930 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 194 3.1E-4 T 11-11-2016 AUP74_RS16750 c0e7a41dd48d8fbf9a647a392ea329ff 361 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 37 361 5.6E-137 T 11-11-2016 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AUP74_RS16750 c0e7a41dd48d8fbf9a647a392ea329ff 361 ProSitePatterns PS01348 MraY family signature 2. 190 201 - T 11-11-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AUP74_RS16750 c0e7a41dd48d8fbf9a647a392ea329ff 361 Pfam PF00953 Glycosyl transferase family 4 99 285 5.0E-37 T 11-11-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 AUP74_RS16750 c0e7a41dd48d8fbf9a647a392ea329ff 361 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 25 359 24.6 T 11-11-2016 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AUP74_RS16750 c0e7a41dd48d8fbf9a647a392ea329ff 361 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 68 80 7.4E-5 T 11-11-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AUP74_RS15775 a6242db5ee1f513333379f665fb9b22c 252 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 4 248 8.2E-65 T 11-11-2016 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 AUP74_RS15775 a6242db5ee1f513333379f665fb9b22c 252 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 252 82.947 T 11-11-2016 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 AUP74_RS15775 a6242db5ee1f513333379f665fb9b22c 252 Gene3D G3DSA:3.20.20.70 2 250 4.4E-86 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS15775 a6242db5ee1f513333379f665fb9b22c 252 SUPERFAMILY SSF63892 2 250 1.57E-79 T 11-11-2016 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 AUP74_RS15775 a6242db5ee1f513333379f665fb9b22c 252 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 4 248 2.9E-85 T 11-11-2016 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 AUP74_RS15800 fc63e6d64f8a30fba461b505e3e1f611 525 SUPERFAMILY SSF52317 8 237 1.15E-56 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS15800 fc63e6d64f8a30fba461b505e3e1f611 525 PRINTS PR00096 Glutamine amidotransferase superfamily signature 81 92 9.8E-7 T 11-11-2016 AUP74_RS15800 fc63e6d64f8a30fba461b505e3e1f611 525 PRINTS PR00096 Glutamine amidotransferase superfamily signature 177 190 9.8E-7 T 11-11-2016 AUP74_RS15800 fc63e6d64f8a30fba461b505e3e1f611 525 PRINTS PR00096 Glutamine amidotransferase superfamily signature 54 63 9.8E-7 T 11-11-2016 AUP74_RS15800 fc63e6d64f8a30fba461b505e3e1f611 525 Gene3D G3DSA:3.40.50.620 223 399 2.4E-61 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS15800 fc63e6d64f8a30fba461b505e3e1f611 525 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 10 205 3.3E-78 T 11-11-2016 IPR004739 GMP synthase, N-terminal GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 AUP74_RS15800 fc63e6d64f8a30fba461b505e3e1f611 525 Pfam PF00958 GMP synthase C terminal domain 433 524 2.1E-42 T 11-11-2016 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 AUP74_RS15800 fc63e6d64f8a30fba461b505e3e1f611 525 Gene3D G3DSA:3.40.50.880 6 222 4.4E-60 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS15800 fc63e6d64f8a30fba461b505e3e1f611 525 SUPERFAMILY SSF54810 405 525 7.72E-51 T 11-11-2016 AUP74_RS15800 fc63e6d64f8a30fba461b505e3e1f611 525 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 7 525 55.716 T 11-11-2016 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 AUP74_RS15800 fc63e6d64f8a30fba461b505e3e1f611 525 PRINTS PR00097 Anthranilate synthase component II signature 81 92 1.3E-5 T 11-11-2016 AUP74_RS15800 fc63e6d64f8a30fba461b505e3e1f611 525 PRINTS PR00097 Anthranilate synthase component II signature 177 190 1.3E-5 T 11-11-2016 AUP74_RS15800 fc63e6d64f8a30fba461b505e3e1f611 525 PRINTS PR00097 Anthranilate synthase component II signature 54 63 1.3E-5 T 11-11-2016 AUP74_RS15800 fc63e6d64f8a30fba461b505e3e1f611 525 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 212 525 1.6E-151 T 11-11-2016 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 AUP74_RS15800 fc63e6d64f8a30fba461b505e3e1f611 525 Gene3D G3DSA:3.30.300.10 401 525 1.6E-53 T 11-11-2016 AUP74_RS15800 fc63e6d64f8a30fba461b505e3e1f611 525 Pfam PF00117 Glutamine amidotransferase class-I 12 200 4.6E-38 T 11-11-2016 IPR017926 Glutamine amidotransferase AUP74_RS15800 fc63e6d64f8a30fba461b505e3e1f611 525 Pfam PF02540 NAD synthase 214 294 2.4E-9 T 11-11-2016 IPR022310 NAD/GMP synthase AUP74_RS15800 fc63e6d64f8a30fba461b505e3e1f611 525 SUPERFAMILY SSF52402 193 446 1.54E-58 T 11-11-2016 AUP74_RS08710 77c4af91da106fc5d739ac9ae623c200 182 Gene3D G3DSA:2.60.120.10 1 178 3.2E-79 T 11-11-2016 IPR014710 RmlC-like jelly roll fold AUP74_RS08710 77c4af91da106fc5d739ac9ae623c200 182 SUPERFAMILY SSF51182 1 177 4.98E-74 T 11-11-2016 IPR011051 RmlC-like cupin domain AUP74_RS08710 77c4af91da106fc5d739ac9ae623c200 182 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 2 175 1.3E-74 T 11-11-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 AUP74_RS08710 77c4af91da106fc5d739ac9ae623c200 182 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 5 174 2.4E-71 T 11-11-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 AUP74_RS08710 77c4af91da106fc5d739ac9ae623c200 182 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 167 8.0E-67 T 11-11-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 AUP74_RS12945 3f8dee07096f1ef2bdadf89b1e57de34 446 SUPERFAMILY SSF56322 17 443 7.46E-126 T 11-11-2016 IPR005801 ADC synthase GO:0009058 AUP74_RS12945 3f8dee07096f1ef2bdadf89b1e57de34 446 Pfam PF04715 Anthranilate synthase component I, N terminal region 13 133 3.7E-15 T 11-11-2016 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058|GO:0016833 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AUP74_RS12945 3f8dee07096f1ef2bdadf89b1e57de34 446 Gene3D G3DSA:3.60.120.10 10 443 8.5E-137 T 11-11-2016 IPR005801 ADC synthase GO:0009058 AUP74_RS12945 3f8dee07096f1ef2bdadf89b1e57de34 446 Pfam PF00425 chorismate binding enzyme 181 434 3.3E-93 T 11-11-2016 IPR015890 Chorismate-utilising enzyme, C-terminal AUP74_RS12945 3f8dee07096f1ef2bdadf89b1e57de34 446 PRINTS PR00095 Anthranilate synthase component I signature 296 309 1.9E-15 T 11-11-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AUP74_RS12945 3f8dee07096f1ef2bdadf89b1e57de34 446 PRINTS PR00095 Anthranilate synthase component I signature 376 390 1.9E-15 T 11-11-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AUP74_RS12945 3f8dee07096f1ef2bdadf89b1e57de34 446 PRINTS PR00095 Anthranilate synthase component I signature 391 405 1.9E-15 T 11-11-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AUP74_RS12945 3f8dee07096f1ef2bdadf89b1e57de34 446 PRINTS PR00095 Anthranilate synthase component I signature 282 295 1.9E-15 T 11-11-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AUP74_RS12945 3f8dee07096f1ef2bdadf89b1e57de34 446 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 89 435 9.8E-113 T 11-11-2016 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 AUP74_RS14960 a865d8a96594f74b0991595cec989aae 312 Gene3D G3DSA:3.40.50.880 9 156 3.4E-15 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS14960 a865d8a96594f74b0991595cec989aae 312 SMART SM00342 206 289 2.1E-24 T 11-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AUP74_RS14960 a865d8a96594f74b0991595cec989aae 312 Gene3D G3DSA:1.10.10.60 244 292 1.6E-19 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS14960 a865d8a96594f74b0991595cec989aae 312 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 273 289 1.2E-6 T 11-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AUP74_RS14960 a865d8a96594f74b0991595cec989aae 312 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 258 273 1.2E-6 T 11-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AUP74_RS14960 a865d8a96594f74b0991595cec989aae 312 SUPERFAMILY SSF46689 190 239 2.02E-5 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS14960 a865d8a96594f74b0991595cec989aae 312 SUPERFAMILY SSF46689 242 293 4.12E-15 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS14960 a865d8a96594f74b0991595cec989aae 312 Gene3D G3DSA:1.10.10.60 189 243 1.4E-8 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS14960 a865d8a96594f74b0991595cec989aae 312 SUPERFAMILY SSF52317 9 156 1.22E-16 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS14960 a865d8a96594f74b0991595cec989aae 312 Pfam PF12833 Helix-turn-helix domain 212 290 4.7E-23 T 11-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AUP74_RS00535 6c90eb936a6369b6ba1f4aaac27b51b5 325 Hamap MF_00492 Transaldolase [tal]. 1 313 48.587 T 11-11-2016 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 AUP74_RS00535 6c90eb936a6369b6ba1f4aaac27b51b5 325 TIGRFAM TIGR00874 talAB: transaldolase 2 310 1.4E-135 T 11-11-2016 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 AUP74_RS00535 6c90eb936a6369b6ba1f4aaac27b51b5 325 Gene3D G3DSA:3.20.20.70 1 310 1.1E-119 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS00535 6c90eb936a6369b6ba1f4aaac27b51b5 325 ProSitePatterns PS00958 Transaldolase active site. 125 142 - T 11-11-2016 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 AUP74_RS00535 6c90eb936a6369b6ba1f4aaac27b51b5 325 SUPERFAMILY SSF51569 1 310 3.39E-105 T 11-11-2016 AUP74_RS00535 6c90eb936a6369b6ba1f4aaac27b51b5 325 Pfam PF00923 Transaldolase 13 308 1.7E-96 T 11-11-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 AUP74_RS00535 6c90eb936a6369b6ba1f4aaac27b51b5 325 ProSitePatterns PS01054 Transaldolase signature 1. 30 38 - T 11-11-2016 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 AUP74_RS12235 979e3f1466af06bcf78aae0870745867 615 Pfam PF02151 UvrB/uvrC motif 214 246 1.8E-10 T 11-11-2016 IPR001943 UVR domain GO:0005515 AUP74_RS12235 979e3f1466af06bcf78aae0870745867 615 SUPERFAMILY SSF47781 526 614 2.67E-25 T 11-11-2016 IPR010994 RuvA domain 2-like AUP74_RS12235 979e3f1466af06bcf78aae0870745867 615 SUPERFAMILY SSF46600 199 251 1.05E-13 T 11-11-2016 IPR001943 UVR domain GO:0005515 AUP74_RS12235 979e3f1466af06bcf78aae0870745867 615 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 390 546 2.7E-50 T 11-11-2016 IPR001162 UvrC family homology region AUP74_RS12235 979e3f1466af06bcf78aae0870745867 615 SMART SM00465 25 106 2.5E-22 T 11-11-2016 IPR000305 GIY-YIG nuclease superfamily AUP74_RS12235 979e3f1466af06bcf78aae0870745867 615 SUPERFAMILY SSF82771 25 108 1.83E-22 T 11-11-2016 IPR000305 GIY-YIG nuclease superfamily AUP74_RS12235 979e3f1466af06bcf78aae0870745867 615 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 16 593 1.3E-194 T 11-11-2016 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 AUP74_RS12235 979e3f1466af06bcf78aae0870745867 615 Hamap MF_00203 UvrABC system protein C [uvrC]. 12 611 29.37 T 11-11-2016 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 AUP74_RS12235 979e3f1466af06bcf78aae0870745867 615 Pfam PF14520 Helix-hairpin-helix domain 562 612 4.6E-11 T 11-11-2016 AUP74_RS12235 979e3f1466af06bcf78aae0870745867 615 Gene3D G3DSA:3.40.1440.10 25 103 4.1E-8 T 11-11-2016 IPR027299 GIY-YIG domain AUP74_RS12235 979e3f1466af06bcf78aae0870745867 615 Gene3D G3DSA:1.10.150.20 560 613 1.5E-24 T 11-11-2016 AUP74_RS12235 979e3f1466af06bcf78aae0870745867 615 SMART SM00278 560 579 2.0 T 11-11-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AUP74_RS12235 979e3f1466af06bcf78aae0870745867 615 SMART SM00278 592 611 1.2 T 11-11-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AUP74_RS12235 979e3f1466af06bcf78aae0870745867 615 Pfam PF01541 GIY-YIG catalytic domain 26 101 2.1E-10 T 11-11-2016 IPR000305 GIY-YIG nuclease superfamily AUP74_RS12235 979e3f1466af06bcf78aae0870745867 615 Gene3D G3DSA:4.10.860.10 191 251 8.7E-20 T 11-11-2016 IPR001943 UVR domain GO:0005515 AUP74_RS08080 7f3de08a4531244d3c2f27b6751349b9 450 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 2 447 46.803 T 11-11-2016 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS08080 7f3de08a4531244d3c2f27b6751349b9 450 SUPERFAMILY SSF53738 261 368 6.67E-27 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS08080 7f3de08a4531244d3c2f27b6751349b9 450 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 161 257 5.3E-18 T 11-11-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS08080 7f3de08a4531244d3c2f27b6751349b9 450 SUPERFAMILY SSF53738 160 260 2.51E-30 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS08080 7f3de08a4531244d3c2f27b6751349b9 450 Gene3D G3DSA:3.40.120.10 254 370 8.0E-30 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS08080 7f3de08a4531244d3c2f27b6751349b9 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 177 196 8.9E-15 T 11-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS08080 7f3de08a4531244d3c2f27b6751349b9 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 237 252 8.9E-15 T 11-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS08080 7f3de08a4531244d3c2f27b6751349b9 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 100 114 8.9E-15 T 11-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS08080 7f3de08a4531244d3c2f27b6751349b9 450 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 6 445 6.5E-185 T 11-11-2016 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS08080 7f3de08a4531244d3c2f27b6751349b9 450 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 139 3.5E-42 T 11-11-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS08080 7f3de08a4531244d3c2f27b6751349b9 450 SUPERFAMILY SSF55957 361 447 1.27E-21 T 11-11-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS08080 7f3de08a4531244d3c2f27b6751349b9 450 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 101 110 - T 11-11-2016 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS08080 7f3de08a4531244d3c2f27b6751349b9 450 Gene3D G3DSA:3.30.310.50 372 446 7.0E-16 T 11-11-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS08080 7f3de08a4531244d3c2f27b6751349b9 450 Gene3D G3DSA:3.40.120.10 3 152 1.4E-45 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS08080 7f3de08a4531244d3c2f27b6751349b9 450 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 376 444 2.1E-15 T 11-11-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS08080 7f3de08a4531244d3c2f27b6751349b9 450 Gene3D G3DSA:3.40.120.10 179 253 7.7E-30 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS08080 7f3de08a4531244d3c2f27b6751349b9 450 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 261 367 2.3E-28 T 11-11-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS08080 7f3de08a4531244d3c2f27b6751349b9 450 SUPERFAMILY SSF53738 2 184 1.81E-47 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS16145 105f24ffb3de03b13f4bfe2a0df232aa 313 Gene3D G3DSA:1.10.8.10 21 111 3.1E-7 T 11-11-2016 AUP74_RS16145 105f24ffb3de03b13f4bfe2a0df232aa 313 Hamap MF_02125 50S ribosomal protein L3 glutamine methyltransferase [prmB]. 11 305 50.578 T 11-11-2016 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 AUP74_RS16145 105f24ffb3de03b13f4bfe2a0df232aa 313 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 209 215 - T 11-11-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 AUP74_RS16145 105f24ffb3de03b13f4bfe2a0df232aa 313 TIGRFAM TIGR03533 L3_gln_methyl: protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 18 299 3.0E-128 T 11-11-2016 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 AUP74_RS16145 105f24ffb3de03b13f4bfe2a0df232aa 313 Pfam PF05175 Methyltransferase small domain 140 220 3.5E-18 T 11-11-2016 IPR007848 Methyltransferase small domain GO:0008168 AUP74_RS16145 105f24ffb3de03b13f4bfe2a0df232aa 313 PIRSF PIRSF037167 2 312 3.3E-132 T 11-11-2016 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 AUP74_RS16145 105f24ffb3de03b13f4bfe2a0df232aa 313 SUPERFAMILY SSF53335 21 298 5.96E-51 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS16145 105f24ffb3de03b13f4bfe2a0df232aa 313 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 20 307 3.0E-79 T 11-11-2016 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 AUP74_RS16145 105f24ffb3de03b13f4bfe2a0df232aa 313 Gene3D G3DSA:3.40.50.150 113 290 2.9E-50 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS05135 a15de588ae69a7812cfe1dfcc9a47fc9 286 SUPERFAMILY SSF161098 51 277 7.59E-65 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AUP74_RS05135 a15de588ae69a7812cfe1dfcc9a47fc9 286 Gene3D G3DSA:1.10.3720.10 56 285 8.6E-68 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AUP74_RS05135 a15de588ae69a7812cfe1dfcc9a47fc9 286 Gene3D G3DSA:1.20.58.370 7 40 1.7E-4 T 11-11-2016 AUP74_RS05135 a15de588ae69a7812cfe1dfcc9a47fc9 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 65 276 1.2E-15 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AUP74_RS05135 a15de588ae69a7812cfe1dfcc9a47fc9 286 SUPERFAMILY SSF160964 4 53 3.14E-5 T 11-11-2016 AUP74_RS10095 68d4af3d50e035a4bcb834b20892fa3a 325 SUPERFAMILY SSF55120 14 313 1.58E-77 T 11-11-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS10095 68d4af3d50e035a4bcb834b20892fa3a 325 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 82 95 - T 11-11-2016 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Reactome: R-HSA-6782315 AUP74_RS10095 68d4af3d50e035a4bcb834b20892fa3a 325 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 230 313 4.3E-7 T 11-11-2016 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS10095 68d4af3d50e035a4bcb834b20892fa3a 325 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 21 174 9.3E-42 T 11-11-2016 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS10095 68d4af3d50e035a4bcb834b20892fa3a 325 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 10 318 26.016 T 11-11-2016 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS13260 a69c0df0f5e1f5b8854442bc658ad5a4 1231 TIGRFAM TIGR02082 metH: methionine synthase 18 1199 0.0 T 11-11-2016 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AUP74_RS13260 a69c0df0f5e1f5b8854442bc658ad5a4 1231 Gene3D G3DSA:3.40.50.280 748 898 1.1E-63 T 11-11-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 AUP74_RS13260 a69c0df0f5e1f5b8854442bc658ad5a4 1231 Gene3D G3DSA:3.20.20.20 367 639 8.2E-115 T 11-11-2016 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AUP74_RS13260 a69c0df0f5e1f5b8854442bc658ad5a4 1231 Pfam PF02607 B12 binding domain 662 734 8.4E-24 T 11-11-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AUP74_RS13260 a69c0df0f5e1f5b8854442bc658ad5a4 1231 SUPERFAMILY SSF56507 906 1229 7.59E-128 T 11-11-2016 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AUP74_RS13260 a69c0df0f5e1f5b8854442bc658ad5a4 1231 Pfam PF00809 Pterin binding enzyme 363 601 4.3E-57 T 11-11-2016 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AUP74_RS13260 a69c0df0f5e1f5b8854442bc658ad5a4 1231 PIRSF PIRSF000381 6 1202 0.0 T 11-11-2016 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AUP74_RS13260 a69c0df0f5e1f5b8854442bc658ad5a4 1231 Gene3D G3DSA:3.20.20.330 6 366 8.4E-125 T 11-11-2016 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 AUP74_RS13260 a69c0df0f5e1f5b8854442bc658ad5a4 1231 Pfam PF02310 B12 binding domain 751 843 5.3E-19 T 11-11-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 AUP74_RS13260 a69c0df0f5e1f5b8854442bc658ad5a4 1231 SUPERFAMILY SSF52242 746 897 7.33E-44 T 11-11-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 AUP74_RS13260 a69c0df0f5e1f5b8854442bc658ad5a4 1231 SUPERFAMILY SSF47644 655 741 1.28E-28 T 11-11-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AUP74_RS13260 a69c0df0f5e1f5b8854442bc658ad5a4 1231 Gene3D G3DSA:3.10.196.10 962 1230 3.3E-106 T 11-11-2016 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AUP74_RS13260 a69c0df0f5e1f5b8854442bc658ad5a4 1231 Gene3D G3DSA:1.10.1240.10 653 739 3.0E-38 T 11-11-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AUP74_RS13260 a69c0df0f5e1f5b8854442bc658ad5a4 1231 SMART SM01018 659 742 7.9E-45 T 11-11-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AUP74_RS13260 a69c0df0f5e1f5b8854442bc658ad5a4 1231 SUPERFAMILY SSF82282 13 402 7.72E-118 T 11-11-2016 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 AUP74_RS13260 a69c0df0f5e1f5b8854442bc658ad5a4 1231 Pfam PF02574 Homocysteine S-methyltransferase 22 328 3.5E-91 T 11-11-2016 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 AUP74_RS13260 a69c0df0f5e1f5b8854442bc658ad5a4 1231 SUPERFAMILY SSF51717 359 633 3.53E-90 T 11-11-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AUP74_RS13260 a69c0df0f5e1f5b8854442bc658ad5a4 1231 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 943 1215 9.4E-123 T 11-11-2016 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AUP74_RS08300 ee66f6d80666d55fab1f002cfa38066b 355 Gene3D G3DSA:2.30.42.10 256 353 1.1E-18 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS08300 ee66f6d80666d55fab1f002cfa38066b 355 Pfam PF13180 PDZ domain 271 351 3.8E-12 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS08300 ee66f6d80666d55fab1f002cfa38066b 355 SUPERFAMILY SSF50494 42 250 1.57E-59 T 11-11-2016 IPR009003 Peptidase S1, PA clan AUP74_RS08300 ee66f6d80666d55fab1f002cfa38066b 355 Gene3D G3DSA:2.40.10.10 144 255 7.9E-46 T 11-11-2016 AUP74_RS08300 ee66f6d80666d55fab1f002cfa38066b 355 Pfam PF13365 Trypsin-like peptidase domain 77 215 7.2E-33 T 11-11-2016 AUP74_RS08300 ee66f6d80666d55fab1f002cfa38066b 355 PRINTS PR00834 HtrA/DegQ protease family signature 300 312 1.5E-45 T 11-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AUP74_RS08300 ee66f6d80666d55fab1f002cfa38066b 355 PRINTS PR00834 HtrA/DegQ protease family signature 86 98 1.5E-45 T 11-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AUP74_RS08300 ee66f6d80666d55fab1f002cfa38066b 355 PRINTS PR00834 HtrA/DegQ protease family signature 107 127 1.5E-45 T 11-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AUP74_RS08300 ee66f6d80666d55fab1f002cfa38066b 355 PRINTS PR00834 HtrA/DegQ protease family signature 186 203 1.5E-45 T 11-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AUP74_RS08300 ee66f6d80666d55fab1f002cfa38066b 355 PRINTS PR00834 HtrA/DegQ protease family signature 149 173 1.5E-45 T 11-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AUP74_RS08300 ee66f6d80666d55fab1f002cfa38066b 355 PRINTS PR00834 HtrA/DegQ protease family signature 208 225 1.5E-45 T 11-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AUP74_RS08300 ee66f6d80666d55fab1f002cfa38066b 355 Gene3D G3DSA:2.40.10.10 34 143 1.9E-29 T 11-11-2016 AUP74_RS08300 ee66f6d80666d55fab1f002cfa38066b 355 SUPERFAMILY SSF50156 236 351 2.93E-15 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS16100 b9ed3142d0669378dc433619a3bfcc93 331 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 142 313 1.8E-14 T 11-11-2016 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AUP74_RS16100 b9ed3142d0669378dc433619a3bfcc93 331 SUPERFAMILY SSF51735 10 154 4.16E-11 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS16100 b9ed3142d0669378dc433619a3bfcc93 331 SUPERFAMILY SSF55347 138 314 5.54E-22 T 11-11-2016 AUP74_RS16100 b9ed3142d0669378dc433619a3bfcc93 331 Gene3D G3DSA:3.40.50.720 9 146 2.7E-14 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS16100 b9ed3142d0669378dc433619a3bfcc93 331 Gene3D G3DSA:3.30.360.10 147 310 1.7E-24 T 11-11-2016 AUP74_RS16100 b9ed3142d0669378dc433619a3bfcc93 331 PIRSF PIRSF000148 6 331 2.1E-48 T 11-11-2016 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 AUP74_RS07040 e8db3d025fb6ba9772de7d88ea9689a2 400 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 11-11-2016 IPR006074 GTP1/OBG, conserved site GO:0005525 AUP74_RS07040 e8db3d025fb6ba9772de7d88ea9689a2 400 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 332 2.0E-146 T 11-11-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 AUP74_RS07040 e8db3d025fb6ba9772de7d88ea9689a2 400 Pfam PF01018 GTP1/OBG 3 158 8.6E-63 T 11-11-2016 IPR006169 GTP1/OBG domain GO:0005525 AUP74_RS07040 e8db3d025fb6ba9772de7d88ea9689a2 400 Gene3D G3DSA:3.40.50.300 160 342 1.8E-47 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS07040 e8db3d025fb6ba9772de7d88ea9689a2 400 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 2.3E-34 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 AUP74_RS07040 e8db3d025fb6ba9772de7d88ea9689a2 400 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 2.3E-34 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 AUP74_RS07040 e8db3d025fb6ba9772de7d88ea9689a2 400 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 2.3E-34 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 AUP74_RS07040 e8db3d025fb6ba9772de7d88ea9689a2 400 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 2.3E-34 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 AUP74_RS07040 e8db3d025fb6ba9772de7d88ea9689a2 400 PIRSF PIRSF002401 1 380 2.3E-138 T 11-11-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 AUP74_RS07040 e8db3d025fb6ba9772de7d88ea9689a2 400 Gene3D G3DSA:2.70.210.12 2 156 1.7E-60 T 11-11-2016 IPR006169 GTP1/OBG domain GO:0005525 AUP74_RS07040 e8db3d025fb6ba9772de7d88ea9689a2 400 Hamap MF_01454 GTPase Obg [obg]. 2 333 48.158 T 11-11-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 AUP74_RS07040 e8db3d025fb6ba9772de7d88ea9689a2 400 Pfam PF01926 50S ribosome-binding GTPase 162 284 1.0E-22 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 AUP74_RS07040 e8db3d025fb6ba9772de7d88ea9689a2 400 SUPERFAMILY SSF82051 2 158 2.62E-58 T 11-11-2016 IPR006169 GTP1/OBG domain GO:0005525 AUP74_RS07040 e8db3d025fb6ba9772de7d88ea9689a2 400 SUPERFAMILY SSF52540 151 345 2.87E-47 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS01425 67009f7663a3445764bfc6fb427601fa 327 SMART SM00240 18 68 2.8E-9 T 11-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 AUP74_RS01425 67009f7663a3445764bfc6fb427601fa 327 SUPERFAMILY SSF49879 17 86 1.17E-19 T 11-11-2016 IPR008984 SMAD/FHA domain GO:0005515 AUP74_RS01425 67009f7663a3445764bfc6fb427601fa 327 Pfam PF00498 FHA domain 20 85 4.0E-14 T 11-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 AUP74_RS01425 67009f7663a3445764bfc6fb427601fa 327 Gene3D G3DSA:2.60.200.20 5 86 1.2E-19 T 11-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 AUP74_RS03580 88c1544ddd02286faaf109c80e4d56a6 468 Gene3D G3DSA:3.10.20.70 5 104 5.3E-36 T 11-11-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AUP74_RS03580 88c1544ddd02286faaf109c80e4d56a6 468 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 258 273 - T 11-11-2016 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 AUP74_RS03580 88c1544ddd02286faaf109c80e4d56a6 468 Gene3D G3DSA:3.30.590.10 105 454 2.4E-134 T 11-11-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 AUP74_RS03580 88c1544ddd02286faaf109c80e4d56a6 468 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 385 397 - T 11-11-2016 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AUP74_RS03580 88c1544ddd02286faaf109c80e4d56a6 468 SUPERFAMILY SSF54368 4 99 3.92E-33 T 11-11-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AUP74_RS03580 88c1544ddd02286faaf109c80e4d56a6 468 ProSitePatterns PS00180 Glutamine synthetase signature 1. 49 67 - T 11-11-2016 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 AUP74_RS03580 88c1544ddd02286faaf109c80e4d56a6 468 Pfam PF00120 Glutamine synthetase, catalytic domain 101 465 4.5E-135 T 11-11-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AUP74_RS03580 88c1544ddd02286faaf109c80e4d56a6 468 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 14 94 1.8E-29 T 11-11-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AUP74_RS03580 88c1544ddd02286faaf109c80e4d56a6 468 SMART SM01230 101 378 6.0E-141 T 11-11-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AUP74_RS03580 88c1544ddd02286faaf109c80e4d56a6 468 SUPERFAMILY SSF55931 101 467 6.38E-136 T 11-11-2016 AUP74_RS03580 88c1544ddd02286faaf109c80e4d56a6 468 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 6 467 2.0E-201 T 11-11-2016 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AUP74_RS02505 dc635f611aa74641ddcf23cea86f34ea 404 Pfam PF00691 OmpA family 300 394 2.9E-21 T 11-11-2016 IPR006665 OmpA-like domain AUP74_RS02505 dc635f611aa74641ddcf23cea86f34ea 404 Gene3D G3DSA:3.30.1330.60 292 401 1.8E-35 T 11-11-2016 IPR006665 OmpA-like domain AUP74_RS02505 dc635f611aa74641ddcf23cea86f34ea 404 SUPERFAMILY SSF103088 293 400 5.23E-32 T 11-11-2016 IPR006665 OmpA-like domain AUP74_RS02505 dc635f611aa74641ddcf23cea86f34ea 404 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 345 362 5.4E-7 T 11-11-2016 AUP74_RS02505 dc635f611aa74641ddcf23cea86f34ea 404 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 383 403 5.4E-7 T 11-11-2016 AUP74_RS02505 dc635f611aa74641ddcf23cea86f34ea 404 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 363 382 5.4E-7 T 11-11-2016 AUP74_RS02505 dc635f611aa74641ddcf23cea86f34ea 404 Pfam PF06078 Bacterial protein of unknown function (DUF937) 7 139 1.8E-11 T 11-11-2016 IPR009282 Protein of unknown function DUF937 AUP74_RS02505 dc635f611aa74641ddcf23cea86f34ea 404 PRINTS PR01021 OMPA domain signature 345 361 4.0E-5 T 11-11-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AUP74_RS02505 dc635f611aa74641ddcf23cea86f34ea 404 PRINTS PR01021 OMPA domain signature 330 345 4.0E-5 T 11-11-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AUP74_RS11565 59f09715df6b583cf06d4e87b9075bbc 210 Pfam PF00881 Nitroreductase family 18 160 1.1E-13 T 11-11-2016 IPR029479 Nitroreductase Reactome: R-HSA-209968 AUP74_RS11565 59f09715df6b583cf06d4e87b9075bbc 210 SUPERFAMILY SSF55469 14 207 5.89E-40 T 11-11-2016 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AUP74_RS11565 59f09715df6b583cf06d4e87b9075bbc 210 Gene3D G3DSA:3.40.109.10 12 209 3.8E-37 T 11-11-2016 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AUP74_RS11565 59f09715df6b583cf06d4e87b9075bbc 210 Hamap MF_01204 Probable malonic semialdehyde reductase RutE [rutE]. 2 210 44.234 T 11-11-2016 IPR023936 NADH dehydrogenase/NAD(P)H nitroreductase, putative, RutE GO:0016491|GO:0055114 AUP74_RS06860 e185a2e150bd4f96dba3a9ace9dc693c 137 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 39.089 T 11-11-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06860 e185a2e150bd4f96dba3a9ace9dc693c 137 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 1.9E-48 T 11-11-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 AUP74_RS06860 e185a2e150bd4f96dba3a9ace9dc693c 137 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 11-11-2016 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS06860 e185a2e150bd4f96dba3a9ace9dc693c 137 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 6.0E-61 T 11-11-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06860 e185a2e150bd4f96dba3a9ace9dc693c 137 SUPERFAMILY SSF54686 1 134 1.44E-55 T 11-11-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 AUP74_RS06860 e185a2e150bd4f96dba3a9ace9dc693c 137 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 11-11-2016 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS06860 e185a2e150bd4f96dba3a9ace9dc693c 137 Gene3D G3DSA:3.90.1170.10 23 134 5.0E-54 T 11-11-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 AUP74_RS06860 e185a2e150bd4f96dba3a9ace9dc693c 137 PRINTS PR00060 Ribosomal protein L16 signature 42 53 1.2E-40 T 11-11-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06860 e185a2e150bd4f96dba3a9ace9dc693c 137 PRINTS PR00060 Ribosomal protein L16 signature 88 117 1.2E-40 T 11-11-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06860 e185a2e150bd4f96dba3a9ace9dc693c 137 PRINTS PR00060 Ribosomal protein L16 signature 58 87 1.2E-40 T 11-11-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06860 e185a2e150bd4f96dba3a9ace9dc693c 137 PRINTS PR00060 Ribosomal protein L16 signature 24 36 1.2E-40 T 11-11-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS01945 384154dc0ff3baa528543d9cbb03e18d 216 Gene3D G3DSA:3.60.15.10 4 212 7.8E-59 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS01945 384154dc0ff3baa528543d9cbb03e18d 216 SMART SM00849 14 194 3.1E-36 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS01945 384154dc0ff3baa528543d9cbb03e18d 216 Pfam PF00753 Metallo-beta-lactamase superfamily 11 194 5.8E-31 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS01945 384154dc0ff3baa528543d9cbb03e18d 216 SUPERFAMILY SSF56281 4 210 1.0E-57 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS06705 d69a4261a4d57595232469c7ac09a853 386 PRINTS PR00992 Alanine racemase signature 170 181 9.8E-40 T 11-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AUP74_RS06705 d69a4261a4d57595232469c7ac09a853 386 PRINTS PR00992 Alanine racemase signature 358 371 9.8E-40 T 11-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AUP74_RS06705 d69a4261a4d57595232469c7ac09a853 386 PRINTS PR00992 Alanine racemase signature 283 298 9.8E-40 T 11-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AUP74_RS06705 d69a4261a4d57595232469c7ac09a853 386 PRINTS PR00992 Alanine racemase signature 212 239 9.8E-40 T 11-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AUP74_RS06705 d69a4261a4d57595232469c7ac09a853 386 PRINTS PR00992 Alanine racemase signature 266 281 9.8E-40 T 11-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AUP74_RS06705 d69a4261a4d57595232469c7ac09a853 386 PRINTS PR00992 Alanine racemase signature 74 92 9.8E-40 T 11-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AUP74_RS06705 d69a4261a4d57595232469c7ac09a853 386 PRINTS PR00992 Alanine racemase signature 304 321 9.8E-40 T 11-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AUP74_RS06705 d69a4261a4d57595232469c7ac09a853 386 PRINTS PR00992 Alanine racemase signature 136 148 9.8E-40 T 11-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AUP74_RS06705 d69a4261a4d57595232469c7ac09a853 386 PRINTS PR00992 Alanine racemase signature 38 54 9.8E-40 T 11-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AUP74_RS06705 d69a4261a4d57595232469c7ac09a853 386 SUPERFAMILY SSF50621 243 377 1.33E-33 T 11-11-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AUP74_RS06705 d69a4261a4d57595232469c7ac09a853 386 Hamap MF_01201 Alanine racemase. 12 376 26.044 T 11-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AUP74_RS06705 d69a4261a4d57595232469c7ac09a853 386 Pfam PF01168 Alanine racemase, N-terminal domain 19 239 4.2E-54 T 11-11-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AUP74_RS06705 d69a4261a4d57595232469c7ac09a853 386 Gene3D G3DSA:3.20.20.10 24 232 1.3E-55 T 11-11-2016 IPR029066 PLP-binding barrel AUP74_RS06705 d69a4261a4d57595232469c7ac09a853 386 SUPERFAMILY SSF51419 19 243 3.05E-52 T 11-11-2016 IPR029066 PLP-binding barrel AUP74_RS06705 d69a4261a4d57595232469c7ac09a853 386 Pfam PF00842 Alanine racemase, C-terminal domain 250 375 1.2E-27 T 11-11-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AUP74_RS06705 d69a4261a4d57595232469c7ac09a853 386 TIGRFAM TIGR00492 alr: alanine racemase 17 376 1.7E-65 T 11-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AUP74_RS06705 d69a4261a4d57595232469c7ac09a853 386 SMART SM01005 250 376 2.7E-37 T 11-11-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AUP74_RS06705 d69a4261a4d57595232469c7ac09a853 386 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 43 53 - T 11-11-2016 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AUP74_RS06705 d69a4261a4d57595232469c7ac09a853 386 Gene3D G3DSA:2.40.37.10 233 378 3.2E-41 T 11-11-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AUP74_RS09755 a7f643c542a553fea1f12d59a6f96df1 488 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 417 437 - T 11-11-2016 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 AUP74_RS09755 a7f643c542a553fea1f12d59a6f96df1 488 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 7 482 2.9E-180 T 11-11-2016 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 AUP74_RS09755 a7f643c542a553fea1f12d59a6f96df1 488 Pfam PF00474 Sodium:solute symporter family 35 435 1.9E-91 T 11-11-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 AUP74_RS09755 a7f643c542a553fea1f12d59a6f96df1 488 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 35 435 8.3E-88 T 11-11-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 AUP74_RS09755 a7f643c542a553fea1f12d59a6f96df1 488 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 157 182 - T 11-11-2016 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 AUP74_RS06290 c82b5015089778527490259243ab0045 416 Pfam PF13356 Domain of unknown function (DUF4102) 3 89 3.6E-17 T 11-11-2016 IPR025166 Domain of unknown function DUF4102 AUP74_RS06290 c82b5015089778527490259243ab0045 416 SUPERFAMILY SSF56349 100 385 2.5E-59 T 11-11-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AUP74_RS06290 c82b5015089778527490259243ab0045 416 Gene3D G3DSA:1.10.443.10 209 381 2.5E-23 T 11-11-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 AUP74_RS06290 c82b5015089778527490259243ab0045 416 Gene3D G3DSA:1.10.150.130 100 194 3.3E-18 T 11-11-2016 IPR023109 Integrase/recombinase, N-terminal AUP74_RS06290 c82b5015089778527490259243ab0045 416 Pfam PF00589 Phage integrase family 210 362 1.9E-13 T 11-11-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AUP74_RS02125 cedd9f02f78e0d95c015cb76f3f87887 956 Pfam PF08238 Sel1 repeat 670 703 0.33 T 11-11-2016 IPR006597 Sel1-like repeat AUP74_RS02125 cedd9f02f78e0d95c015cb76f3f87887 956 Pfam PF08238 Sel1 repeat 641 669 8.0E-4 T 11-11-2016 IPR006597 Sel1-like repeat AUP74_RS02125 cedd9f02f78e0d95c015cb76f3f87887 956 Gene3D G3DSA:1.25.40.10 619 765 3.0E-18 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS02125 cedd9f02f78e0d95c015cb76f3f87887 956 Pfam PF00326 Prolyl oligopeptidase family 417 622 2.1E-26 T 11-11-2016 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 AUP74_RS02125 cedd9f02f78e0d95c015cb76f3f87887 956 Pfam PF12975 Domain of unknown function (DUF3859) 837 949 4.9E-13 T 11-11-2016 IPR024331 Domain of unknown function DUF3859 AUP74_RS02125 cedd9f02f78e0d95c015cb76f3f87887 956 SUPERFAMILY SSF81901 646 767 2.35E-12 T 11-11-2016 AUP74_RS02125 cedd9f02f78e0d95c015cb76f3f87887 956 SUPERFAMILY SSF53474 378 622 1.71E-47 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS02125 cedd9f02f78e0d95c015cb76f3f87887 956 SMART SM00671 670 704 5.6 T 11-11-2016 IPR006597 Sel1-like repeat AUP74_RS02125 cedd9f02f78e0d95c015cb76f3f87887 956 SMART SM00671 634 669 0.038 T 11-11-2016 IPR006597 Sel1-like repeat AUP74_RS02125 cedd9f02f78e0d95c015cb76f3f87887 956 Gene3D G3DSA:3.40.50.1820 327 618 5.1E-49 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS02125 cedd9f02f78e0d95c015cb76f3f87887 956 SUPERFAMILY SSF82171 29 260 1.2E-7 T 11-11-2016 AUP74_RS02125 cedd9f02f78e0d95c015cb76f3f87887 956 SUPERFAMILY SSF82171 319 365 1.2E-7 T 11-11-2016 AUP74_RS07460 41be808ad456104ef47043ccc3ef1d4d 628 SUPERFAMILY SSF69593 387 610 3.01E-31 T 11-11-2016 AUP74_RS07460 41be808ad456104ef47043ccc3ef1d4d 628 Pfam PF01553 Acyltransferase 443 571 3.4E-27 T 11-11-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 AUP74_RS07460 41be808ad456104ef47043ccc3ef1d4d 628 Gene3D G3DSA:1.20.1250.20 224 426 1.4E-9 T 11-11-2016 AUP74_RS07460 41be808ad456104ef47043ccc3ef1d4d 628 Gene3D G3DSA:1.20.1250.20 13 197 2.0E-5 T 11-11-2016 AUP74_RS07460 41be808ad456104ef47043ccc3ef1d4d 628 SUPERFAMILY SSF103473 10 427 3.92E-25 T 11-11-2016 IPR020846 Major facilitator superfamily domain AUP74_RS07460 41be808ad456104ef47043ccc3ef1d4d 628 Pfam PF07690 Major Facilitator Superfamily 19 316 1.4E-9 T 11-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AUP74_RS07460 41be808ad456104ef47043ccc3ef1d4d 628 SMART SM00563 458 574 5.2E-29 T 11-11-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 AUP74_RS07460 41be808ad456104ef47043ccc3ef1d4d 628 Gene3D G3DSA:3.40.1130.10 427 571 1.2E-17 T 11-11-2016 AUP74_RS07015 1cb6894a38df5ffe8b5b0112d3c04dd0 282 SUPERFAMILY SSF53448 3 270 5.86E-61 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases AUP74_RS07015 1cb6894a38df5ffe8b5b0112d3c04dd0 282 Pfam PF00483 Nucleotidyl transferase 10 266 2.1E-27 T 11-11-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 AUP74_RS07015 1cb6894a38df5ffe8b5b0112d3c04dd0 282 Gene3D G3DSA:3.90.550.10 4 268 1.8E-64 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases AUP74_RS07015 1cb6894a38df5ffe8b5b0112d3c04dd0 282 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 2 263 5.3E-117 T 11-11-2016 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343 AUP74_RS12820 aa42faeb74406a3e2dffb10664dfbde7 72 Gene3D G3DSA:2.40.50.140 1 71 6.0E-39 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS12820 aa42faeb74406a3e2dffb10664dfbde7 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 27.238 T 11-11-2016 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 AUP74_RS12820 aa42faeb74406a3e2dffb10664dfbde7 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 4.1E-28 T 11-11-2016 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 AUP74_RS12820 aa42faeb74406a3e2dffb10664dfbde7 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 70 9.7E-38 T 11-11-2016 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 AUP74_RS12820 aa42faeb74406a3e2dffb10664dfbde7 72 SMART SM00316 4 72 5.3E-5 T 11-11-2016 IPR022967 RNA-binding domain, S1 AUP74_RS12820 aa42faeb74406a3e2dffb10664dfbde7 72 SUPERFAMILY SSF50249 1 70 2.1E-28 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS12775 e7be9fe111d460756e582b82bf04866d 460 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 297 330 - T 11-11-2016 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 AUP74_RS12775 e7be9fe111d460756e582b82bf04866d 460 SUPERFAMILY SSF53790 213 460 1.7E-82 T 11-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 AUP74_RS12775 e7be9fe111d460756e582b82bf04866d 460 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 4 206 1.6E-64 T 11-11-2016 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 AUP74_RS12775 e7be9fe111d460756e582b82bf04866d 460 SUPERFAMILY SSF75615 114 208 6.15E-21 T 11-11-2016 AUP74_RS12775 e7be9fe111d460756e582b82bf04866d 460 Gene3D G3DSA:3.40.1010.10 216 332 6.2E-47 T 11-11-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 AUP74_RS12775 e7be9fe111d460756e582b82bf04866d 460 SUPERFAMILY SSF51735 2 113 5.32E-23 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS12775 e7be9fe111d460756e582b82bf04866d 460 Gene3D G3DSA:3.30.950.10 333 459 5.7E-49 T 11-11-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 AUP74_RS12775 e7be9fe111d460756e582b82bf04866d 460 Gene3D G3DSA:3.40.50.720 2 111 1.7E-33 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS12775 e7be9fe111d460756e582b82bf04866d 460 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 217 452 9.8E-92 T 11-11-2016 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 AUP74_RS12775 e7be9fe111d460756e582b82bf04866d 460 Hamap MF_01646 Siroheme synthase [cysG]. 1 460 49.688 T 11-11-2016 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 AUP74_RS12775 e7be9fe111d460756e582b82bf04866d 460 Gene3D G3DSA:1.10.8.210 150 209 9.1E-17 T 11-11-2016 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 AUP74_RS12775 e7be9fe111d460756e582b82bf04866d 460 Pfam PF13241 Putative NAD(P)-binding 6 115 2.5E-27 T 11-11-2016 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 AUP74_RS12775 e7be9fe111d460756e582b82bf04866d 460 Gene3D G3DSA:3.30.160.110 113 147 1.1E-14 T 11-11-2016 AUP74_RS12775 e7be9fe111d460756e582b82bf04866d 460 Pfam PF10414 Sirohaem synthase dimerisation region 150 206 9.3E-18 T 11-11-2016 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 AUP74_RS12775 e7be9fe111d460756e582b82bf04866d 460 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 219 428 1.2E-51 T 11-11-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 AUP74_RS12775 e7be9fe111d460756e582b82bf04866d 460 PIRSF PIRSF036426 1 460 9.0E-192 T 11-11-2016 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 AUP74_RS11860 373ad4b05fb59c2e55550aa9ba73b75b 201 Gene3D G3DSA:2.10.109.10 75 199 1.4E-43 T 11-11-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain AUP74_RS11860 373ad4b05fb59c2e55550aa9ba73b75b 201 Pfam PF01726 LexA DNA binding domain 1 65 4.3E-30 T 11-11-2016 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 AUP74_RS11860 373ad4b05fb59c2e55550aa9ba73b75b 201 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 110 120 2.2E-13 T 11-11-2016 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 AUP74_RS11860 373ad4b05fb59c2e55550aa9ba73b75b 201 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 149 161 2.2E-13 T 11-11-2016 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 AUP74_RS11860 373ad4b05fb59c2e55550aa9ba73b75b 201 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 121 132 2.2E-13 T 11-11-2016 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 AUP74_RS11860 373ad4b05fb59c2e55550aa9ba73b75b 201 SUPERFAMILY SSF51306 75 198 3.84E-36 T 11-11-2016 IPR015927 Peptidase S24/S26A/S26B/S26C AUP74_RS11860 373ad4b05fb59c2e55550aa9ba73b75b 201 Pfam PF00717 Peptidase S24-like 113 167 4.4E-13 T 11-11-2016 IPR019759 Peptidase S24/S26A/S26B AUP74_RS11860 373ad4b05fb59c2e55550aa9ba73b75b 201 Gene3D G3DSA:1.10.10.10 1 69 9.4E-29 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS11860 373ad4b05fb59c2e55550aa9ba73b75b 201 TIGRFAM TIGR00498 lexA: repressor LexA 1 199 4.2E-75 T 11-11-2016 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 AUP74_RS11860 373ad4b05fb59c2e55550aa9ba73b75b 201 SUPERFAMILY SSF46785 3 70 6.92E-21 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS11860 373ad4b05fb59c2e55550aa9ba73b75b 201 Hamap MF_00015 LexA repressor [lexA]. 3 200 32.435 T 11-11-2016 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 AUP74_RS15155 56bcbe8cdd7f74203e740c4dd990430f 506 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 279 291 - T 11-11-2016 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AUP74_RS15155 56bcbe8cdd7f74203e740c4dd990430f 506 PIRSF PIRSF000109 1 505 5.6E-174 T 11-11-2016 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AUP74_RS15155 56bcbe8cdd7f74203e740c4dd990430f 506 Gene3D G3DSA:1.10.1040.10 206 461 3.4E-106 T 11-11-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AUP74_RS15155 56bcbe8cdd7f74203e740c4dd990430f 506 SMART SM01350 204 497 2.4E-197 T 11-11-2016 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AUP74_RS15155 56bcbe8cdd7f74203e740c4dd990430f 506 SUPERFAMILY SSF48179 202 500 7.48E-118 T 11-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AUP74_RS15155 56bcbe8cdd7f74203e740c4dd990430f 506 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 204 496 1.7E-121 T 11-11-2016 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AUP74_RS15155 56bcbe8cdd7f74203e740c4dd990430f 506 Gene3D G3DSA:1.20.5.320 463 503 4.6E-19 T 11-11-2016 IPR012284 6-phosphogluconate dehydrogenase, domain 3 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AUP74_RS15155 56bcbe8cdd7f74203e740c4dd990430f 506 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 6 29 2.5E-39 T 11-11-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AUP74_RS15155 56bcbe8cdd7f74203e740c4dd990430f 506 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 275 302 2.5E-39 T 11-11-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AUP74_RS15155 56bcbe8cdd7f74203e740c4dd990430f 506 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 384 406 2.5E-39 T 11-11-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AUP74_RS15155 56bcbe8cdd7f74203e740c4dd990430f 506 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 74 103 2.5E-39 T 11-11-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AUP74_RS15155 56bcbe8cdd7f74203e740c4dd990430f 506 Gene3D G3DSA:3.40.50.720 6 205 5.2E-44 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS15155 56bcbe8cdd7f74203e740c4dd990430f 506 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 7 172 3.0E-33 T 11-11-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 AUP74_RS15155 56bcbe8cdd7f74203e740c4dd990430f 506 SUPERFAMILY SSF51735 6 172 2.25E-38 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS15155 56bcbe8cdd7f74203e740c4dd990430f 506 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 7 498 7.9E-171 T 11-11-2016 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AUP74_RS14705 b7f70f78540d83079762bdf5473b5304 101 Pfam PF00216 Bacterial DNA-binding protein 5 93 6.5E-31 T 11-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 AUP74_RS14705 b7f70f78540d83079762bdf5473b5304 101 SUPERFAMILY SSF47729 5 95 5.59E-32 T 11-11-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 AUP74_RS14705 b7f70f78540d83079762bdf5473b5304 101 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 3 99 30.242 T 11-11-2016 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 AUP74_RS14705 b7f70f78540d83079762bdf5473b5304 101 PRINTS PR01727 Prokaryotic integration host factor signature 44 59 2.3E-17 T 11-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 AUP74_RS14705 b7f70f78540d83079762bdf5473b5304 101 PRINTS PR01727 Prokaryotic integration host factor signature 78 92 2.3E-17 T 11-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 AUP74_RS14705 b7f70f78540d83079762bdf5473b5304 101 PRINTS PR01727 Prokaryotic integration host factor signature 62 75 2.3E-17 T 11-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 AUP74_RS14705 b7f70f78540d83079762bdf5473b5304 101 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 50 69 - T 11-11-2016 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 AUP74_RS14705 b7f70f78540d83079762bdf5473b5304 101 TIGRFAM TIGR00987 himA: integration host factor, alpha subunit 4 98 1.8E-50 T 11-11-2016 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 AUP74_RS14705 b7f70f78540d83079762bdf5473b5304 101 SMART SM00411 5 94 4.9E-40 T 11-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 AUP74_RS14705 b7f70f78540d83079762bdf5473b5304 101 Gene3D G3DSA:4.10.520.10 4 95 1.1E-35 T 11-11-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 AUP74_RS10805 9bd800a83a6f5e8d293856fdcd7f6d71 226 Gene3D G3DSA:3.40.50.880 1 225 1.5E-98 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS10805 9bd800a83a6f5e8d293856fdcd7f6d71 226 Pfam PF01965 DJ-1/PfpI family 25 222 1.2E-17 T 11-11-2016 IPR002818 DJ-1/PfpI AUP74_RS10805 9bd800a83a6f5e8d293856fdcd7f6d71 226 SUPERFAMILY SSF52317 1 224 2.66E-80 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS06515 acb0cb78316e27f132f36e5f73ce7b63 446 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 154 168 - T 11-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AUP74_RS06515 acb0cb78316e27f132f36e5f73ce7b63 446 SUPERFAMILY SSF56059 83 352 5.3E-68 T 11-11-2016 AUP74_RS06515 acb0cb78316e27f132f36e5f73ce7b63 446 SUPERFAMILY SSF52440 1 113 4.24E-46 T 11-11-2016 IPR016185 Pre-ATP-grasp domain AUP74_RS06515 acb0cb78316e27f132f36e5f73ce7b63 446 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 322 2.2E-81 T 11-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AUP74_RS06515 acb0cb78316e27f132f36e5f73ce7b63 446 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 11-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AUP74_RS06515 acb0cb78316e27f132f36e5f73ce7b63 446 Pfam PF02785 Biotin carboxylase C-terminal domain 336 441 1.9E-38 T 11-11-2016 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AUP74_RS06515 acb0cb78316e27f132f36e5f73ce7b63 446 SMART SM00878 336 441 3.2E-63 T 11-11-2016 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AUP74_RS06515 acb0cb78316e27f132f36e5f73ce7b63 446 SUPERFAMILY SSF51246 331 444 4.92E-42 T 11-11-2016 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AUP74_RS06515 acb0cb78316e27f132f36e5f73ce7b63 446 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 444 7.9E-228 T 11-11-2016 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 AUP74_RS06515 acb0cb78316e27f132f36e5f73ce7b63 446 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 8.4E-44 T 11-11-2016 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AUP74_RS06515 acb0cb78316e27f132f36e5f73ce7b63 446 Gene3D G3DSA:3.40.50.20 1 129 9.1E-50 T 11-11-2016 IPR016185 Pre-ATP-grasp domain AUP74_RS06515 acb0cb78316e27f132f36e5f73ce7b63 446 Gene3D G3DSA:3.30.1490.20 130 203 1.3E-28 T 11-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 AUP74_RS06515 acb0cb78316e27f132f36e5f73ce7b63 446 Gene3D G3DSA:3.30.470.20 204 444 3.5E-97 T 11-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 AUP74_RS10785 3654da2f9dcc8dee2567333dcf6963f3 491 SUPERFAMILY SSF56954 4 459 2.22E-97 T 11-11-2016 AUP74_RS10785 3654da2f9dcc8dee2567333dcf6963f3 491 Gene3D G3DSA:1.20.1600.10 54 459 3.3E-100 T 11-11-2016 AUP74_RS10785 3654da2f9dcc8dee2567333dcf6963f3 491 Pfam PF02321 Outer membrane efflux protein 63 245 2.5E-29 T 11-11-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 AUP74_RS10785 3654da2f9dcc8dee2567333dcf6963f3 491 Pfam PF02321 Outer membrane efflux protein 276 440 4.3E-16 T 11-11-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 AUP74_RS10785 3654da2f9dcc8dee2567333dcf6963f3 491 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 11 457 3.8E-94 T 11-11-2016 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 AUP74_RS02945 9a055ce0b8d0fa8a44cef61d2aa4cb4f 1339 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 198 209 - T 11-11-2016 IPR023827 Peptidase S8, subtilisin, Asp-active site AUP74_RS02945 9a055ce0b8d0fa8a44cef61d2aa4cb4f 1339 Pfam PF00082 Subtilase family 194 462 1.8E-52 T 11-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AUP74_RS02945 9a055ce0b8d0fa8a44cef61d2aa4cb4f 1339 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 241 251 - T 11-11-2016 IPR022398 Peptidase S8, subtilisin, His-active site AUP74_RS02945 9a055ce0b8d0fa8a44cef61d2aa4cb4f 1339 Pfam PF02412 Thrombospondin type 3 repeat 1117 1142 0.013 T 11-11-2016 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 AUP74_RS02945 9a055ce0b8d0fa8a44cef61d2aa4cb4f 1339 Gene3D G3DSA:4.10.1080.10 1096 1221 3.0E-23 T 11-11-2016 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 AUP74_RS02945 9a055ce0b8d0fa8a44cef61d2aa4cb4f 1339 SUPERFAMILY SSF103647 1090 1184 1.44E-12 T 11-11-2016 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 AUP74_RS02945 9a055ce0b8d0fa8a44cef61d2aa4cb4f 1339 SUPERFAMILY SSF52743 70 473 9.3E-82 T 11-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AUP74_RS02945 9a055ce0b8d0fa8a44cef61d2aa4cb4f 1339 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 414 424 - T 11-11-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site AUP74_RS02945 9a055ce0b8d0fa8a44cef61d2aa4cb4f 1339 Gene3D G3DSA:3.40.50.200 144 473 2.4E-82 T 11-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AUP74_RS02945 9a055ce0b8d0fa8a44cef61d2aa4cb4f 1339 PRINTS PR00723 Subtilisin serine protease family (S8) signature 413 429 1.3E-18 T 11-11-2016 IPR015500 Peptidase S8, subtilisin-related AUP74_RS02945 9a055ce0b8d0fa8a44cef61d2aa4cb4f 1339 PRINTS PR00723 Subtilisin serine protease family (S8) signature 237 250 1.3E-18 T 11-11-2016 IPR015500 Peptidase S8, subtilisin-related AUP74_RS02945 9a055ce0b8d0fa8a44cef61d2aa4cb4f 1339 PRINTS PR00723 Subtilisin serine protease family (S8) signature 193 212 1.3E-18 T 11-11-2016 IPR015500 Peptidase S8, subtilisin-related AUP74_RS08145 478cbb6ade227169b80d50c4bffbb96b 3462 SUPERFAMILY SSF117074 2818 2903 1.83E-8 T 11-11-2016 AUP74_RS08145 478cbb6ade227169b80d50c4bffbb96b 3462 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 1326 1435 7.6E-11 T 11-11-2016 IPR026466 Fimbrial isopeptide formation D2 domain AUP74_RS08145 478cbb6ade227169b80d50c4bffbb96b 3462 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 1755 1878 9.2E-8 T 11-11-2016 IPR026466 Fimbrial isopeptide formation D2 domain AUP74_RS08145 478cbb6ade227169b80d50c4bffbb96b 3462 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1336 1380 8.7E-6 T 11-11-2016 IPR001434 Domain of unknown function DUF11 AUP74_RS08145 478cbb6ade227169b80d50c4bffbb96b 3462 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1465 1515 8.6E-6 T 11-11-2016 IPR001434 Domain of unknown function DUF11 AUP74_RS08145 478cbb6ade227169b80d50c4bffbb96b 3462 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 353 394 5.6E-5 T 11-11-2016 IPR001434 Domain of unknown function DUF11 AUP74_RS08145 478cbb6ade227169b80d50c4bffbb96b 3462 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1770 1804 5.8E-9 T 11-11-2016 IPR001434 Domain of unknown function DUF11 AUP74_RS08145 478cbb6ade227169b80d50c4bffbb96b 3462 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2566 2612 4.3E-15 T 11-11-2016 IPR001434 Domain of unknown function DUF11 AUP74_RS08145 478cbb6ade227169b80d50c4bffbb96b 3462 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 853 888 8.4E-7 T 11-11-2016 IPR001434 Domain of unknown function DUF11 AUP74_RS08145 478cbb6ade227169b80d50c4bffbb96b 3462 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2246 2277 1.8E-4 T 11-11-2016 IPR001434 Domain of unknown function DUF11 AUP74_RS08145 478cbb6ade227169b80d50c4bffbb96b 3462 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2401 2449 3.4E-11 T 11-11-2016 IPR001434 Domain of unknown function DUF11 AUP74_RS08145 478cbb6ade227169b80d50c4bffbb96b 3462 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 3136 3187 6.3E-7 T 11-11-2016 IPR001434 Domain of unknown function DUF11 AUP74_RS08145 478cbb6ade227169b80d50c4bffbb96b 3462 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 697 745 2.6E-6 T 11-11-2016 IPR001434 Domain of unknown function DUF11 AUP74_RS08145 478cbb6ade227169b80d50c4bffbb96b 3462 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2722 2771 1.2E-6 T 11-11-2016 IPR001434 Domain of unknown function DUF11 AUP74_RS08145 478cbb6ade227169b80d50c4bffbb96b 3462 Pfam PF01345 Domain of unknown function DUF11 3119 3182 1.7E-8 T 11-11-2016 IPR001434 Domain of unknown function DUF11 AUP74_RS08145 478cbb6ade227169b80d50c4bffbb96b 3462 Pfam PF01345 Domain of unknown function DUF11 2399 2444 6.1E-11 T 11-11-2016 IPR001434 Domain of unknown function DUF11 AUP74_RS08145 478cbb6ade227169b80d50c4bffbb96b 3462 Pfam PF01345 Domain of unknown function DUF11 850 887 1.3E-6 T 11-11-2016 IPR001434 Domain of unknown function DUF11 AUP74_RS08145 478cbb6ade227169b80d50c4bffbb96b 3462 Pfam PF01345 Domain of unknown function DUF11 2690 2766 4.7E-6 T 11-11-2016 IPR001434 Domain of unknown function DUF11 AUP74_RS08145 478cbb6ade227169b80d50c4bffbb96b 3462 Pfam PF01345 Domain of unknown function DUF11 326 393 3.0E-7 T 11-11-2016 IPR001434 Domain of unknown function DUF11 AUP74_RS08145 478cbb6ade227169b80d50c4bffbb96b 3462 Pfam PF01345 Domain of unknown function DUF11 2552 2606 1.7E-11 T 11-11-2016 IPR001434 Domain of unknown function DUF11 AUP74_RS08145 478cbb6ade227169b80d50c4bffbb96b 3462 Pfam PF01345 Domain of unknown function DUF11 1766 1806 6.0E-11 T 11-11-2016 IPR001434 Domain of unknown function DUF11 AUP74_RS08145 478cbb6ade227169b80d50c4bffbb96b 3462 Gene3D G3DSA:2.60.40.10 2853 2920 2.9E-11 T 11-11-2016 IPR013783 Immunoglobulin-like fold AUP74_RS15765 746f105154bf8eb0a349591f2ea11603 228 Gene3D G3DSA:2.30.30.40 54 88 4.5E-4 T 11-11-2016 AUP74_RS15765 746f105154bf8eb0a349591f2ea11603 228 TIGRFAM TIGR04211 SH3_and_anchor: SH3 domain protein 29 226 9.3E-56 T 11-11-2016 IPR016476 SH3 domain protein AUP74_RS15765 746f105154bf8eb0a349591f2ea11603 228 Pfam PF08239 Bacterial SH3 domain 38 88 6.2E-8 T 11-11-2016 IPR003646 SH3-like domain, bacterial-type AUP74_RS15765 746f105154bf8eb0a349591f2ea11603 228 SMART SM00287 25 92 9.0E-5 T 11-11-2016 IPR003646 SH3-like domain, bacterial-type AUP74_RS03945 a0ac8f1100a7c608d981834e837e1039 404 SMART SM00382 194 372 5.9E-9 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS03945 a0ac8f1100a7c608d981834e837e1039 404 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 123 396 62.718 T 11-11-2016 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 AUP74_RS03945 a0ac8f1100a7c608d981834e837e1039 404 SUPERFAMILY SSF52540 145 398 7.44E-52 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03945 a0ac8f1100a7c608d981834e837e1039 404 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 124 395 8.3E-111 T 11-11-2016 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 AUP74_RS03945 a0ac8f1100a7c608d981834e837e1039 404 SMART SM00963 99 180 2.7E-27 T 11-11-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AUP74_RS03945 a0ac8f1100a7c608d981834e837e1039 404 SMART SM00962 195 396 7.4E-122 T 11-11-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AUP74_RS03945 a0ac8f1100a7c608d981834e837e1039 404 Pfam PF00448 SRP54-type protein, GTPase domain 196 395 1.9E-77 T 11-11-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AUP74_RS03945 a0ac8f1100a7c608d981834e837e1039 404 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 369 382 - T 11-11-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AUP74_RS03945 a0ac8f1100a7c608d981834e837e1039 404 Gene3D G3DSA:3.40.50.300 192 396 7.1E-83 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03945 a0ac8f1100a7c608d981834e837e1039 404 Pfam PF02881 SRP54-type protein, helical bundle domain 112 176 7.5E-15 T 11-11-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AUP74_RS03945 a0ac8f1100a7c608d981834e837e1039 404 Gene3D G3DSA:1.20.120.140 85 176 1.1E-31 T 11-11-2016 AUP74_RS06150 2d9bd0055c9284e51b4016c6bf149e3f 381 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 291 377 3.4E-20 T 11-11-2016 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 AUP74_RS06150 2d9bd0055c9284e51b4016c6bf149e3f 381 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 156 223 3.6E-16 T 11-11-2016 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 AUP74_RS06150 2d9bd0055c9284e51b4016c6bf149e3f 381 Gene3D G3DSA:3.40.47.10 8 210 1.6E-46 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS06150 2d9bd0055c9284e51b4016c6bf149e3f 381 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 153 169 - T 11-11-2016 IPR018201 Beta-ketoacyl synthase, active site AUP74_RS06150 2d9bd0055c9284e51b4016c6bf149e3f 381 SUPERFAMILY SSF53901 7 378 5.22E-52 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS06150 2d9bd0055c9284e51b4016c6bf149e3f 381 Gene3D G3DSA:3.40.47.10 211 377 5.6E-26 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS12215 ee35c6720ed6e5ffcdeef818e3294dca 256 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 6 248 6.7E-90 T 11-11-2016 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 AUP74_RS12215 ee35c6720ed6e5ffcdeef818e3294dca 256 Pfam PF02348 Cytidylyltransferase 9 228 4.8E-54 T 11-11-2016 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 AUP74_RS12215 ee35c6720ed6e5ffcdeef818e3294dca 256 Gene3D G3DSA:3.90.550.10 9 256 1.4E-73 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases AUP74_RS12215 ee35c6720ed6e5ffcdeef818e3294dca 256 Hamap MF_00057 3-deoxy-manno-octulosonate cytidylyltransferase [kdsB]. 5 255 42.771 T 11-11-2016 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 AUP74_RS12215 ee35c6720ed6e5ffcdeef818e3294dca 256 SUPERFAMILY SSF53448 7 254 3.6E-57 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases AUP74_RS10025 806d4300b010f98da4bf0b0b98288b21 176 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 122 1.8E-8 T 11-11-2016 IPR001451 Hexapeptide repeat AUP74_RS10025 806d4300b010f98da4bf0b0b98288b21 176 SUPERFAMILY SSF51161 12 168 9.84E-46 T 11-11-2016 IPR011004 Trimeric LpxA-like AUP74_RS10025 806d4300b010f98da4bf0b0b98288b21 176 Gene3D G3DSA:2.160.10.10 14 168 6.0E-43 T 11-11-2016 AUP74_RS12280 701f7297b0d6f327a434af16888e5831 190 Pfam PF06938 Protein of unknown function (DUF1285) 35 164 1.8E-47 T 11-11-2016 IPR010707 Protein of unknown function DUF1285 AUP74_RS12280 701f7297b0d6f327a434af16888e5831 190 Gene3D G3DSA:3.10.540.10 17 85 9.0E-35 T 11-11-2016 AUP74_RS12280 701f7297b0d6f327a434af16888e5831 190 Gene3D G3DSA:2.30.270.10 86 155 1.3E-19 T 11-11-2016 IPR023361 Protein of unknown function DUF1285, beta-roll domain AUP74_RS06055 69fc61d2d44d0485e58c015606d834b6 190 SMART SM00841 131 186 3.0E-31 T 11-11-2016 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 AUP74_RS06055 69fc61d2d44d0485e58c015606d834b6 190 Pfam PF09285 Elongation factor P, C-terminal 131 186 4.9E-25 T 11-11-2016 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 AUP74_RS06055 69fc61d2d44d0485e58c015606d834b6 190 Pfam PF01132 Elongation factor P (EF-P) OB domain 70 123 1.2E-24 T 11-11-2016 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 AUP74_RS06055 69fc61d2d44d0485e58c015606d834b6 190 TIGRFAM TIGR00038 efp: translation elongation factor P 4 187 4.4E-78 T 11-11-2016 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 AUP74_RS06055 69fc61d2d44d0485e58c015606d834b6 190 SUPERFAMILY SSF50104 2 63 2.31E-21 T 11-11-2016 IPR008991 Translation protein SH3-like domain AUP74_RS06055 69fc61d2d44d0485e58c015606d834b6 190 Gene3D G3DSA:2.40.50.140 131 187 4.4E-27 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS06055 69fc61d2d44d0485e58c015606d834b6 190 PIRSF PIRSF005901 2 188 1.3E-67 T 11-11-2016 IPR020599 Translation elongation factor P/YeiP AUP74_RS06055 69fc61d2d44d0485e58c015606d834b6 190 SUPERFAMILY SSF50249 69 128 2.1E-18 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS06055 69fc61d2d44d0485e58c015606d834b6 190 Gene3D G3DSA:2.30.30.30 1 65 2.9E-30 T 11-11-2016 IPR014722 Ribosomal protein L2 domain 2 AUP74_RS06055 69fc61d2d44d0485e58c015606d834b6 190 Gene3D G3DSA:2.40.50.140 66 129 5.9E-27 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS06055 69fc61d2d44d0485e58c015606d834b6 190 SUPERFAMILY SSF50249 130 187 1.88E-17 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS06055 69fc61d2d44d0485e58c015606d834b6 190 Hamap MF_00141 Elongation factor P [efp]. 3 187 48.972 T 11-11-2016 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 AUP74_RS06055 69fc61d2d44d0485e58c015606d834b6 190 SMART SM01185 69 123 7.6E-29 T 11-11-2016 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 AUP74_RS06055 69fc61d2d44d0485e58c015606d834b6 190 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 5 62 2.1E-26 T 11-11-2016 IPR013185 Translation elongation factor, KOW-like AUP74_RS06055 69fc61d2d44d0485e58c015606d834b6 190 ProSitePatterns PS01275 Elongation factor P signature. 152 171 - T 11-11-2016 IPR013852 Translation elongation factor P/YeiP, conserved site AUP74_RS15320 5f740325ca65fc71711c6deaff313fcd 217 TIGRFAM TIGR01351 adk: adenylate kinase 2 216 1.2E-74 T 11-11-2016 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219 AUP74_RS15320 5f740325ca65fc71711c6deaff313fcd 217 Pfam PF00406 Adenylate kinase 5 185 1.3E-55 T 11-11-2016 AUP74_RS15320 5f740325ca65fc71711c6deaff313fcd 217 Hamap MF_00235 Adenylate kinase [adk]. 1 217 52.753 T 11-11-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AUP74_RS15320 5f740325ca65fc71711c6deaff313fcd 217 PRINTS PR00094 Adenylate kinase signature 173 187 4.6E-35 T 11-11-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AUP74_RS15320 5f740325ca65fc71711c6deaff313fcd 217 PRINTS PR00094 Adenylate kinase signature 4 17 4.6E-35 T 11-11-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AUP74_RS15320 5f740325ca65fc71711c6deaff313fcd 217 PRINTS PR00094 Adenylate kinase signature 81 97 4.6E-35 T 11-11-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AUP74_RS15320 5f740325ca65fc71711c6deaff313fcd 217 PRINTS PR00094 Adenylate kinase signature 32 46 4.6E-35 T 11-11-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AUP74_RS15320 5f740325ca65fc71711c6deaff313fcd 217 PRINTS PR00094 Adenylate kinase signature 156 171 4.6E-35 T 11-11-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AUP74_RS15320 5f740325ca65fc71711c6deaff313fcd 217 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 11-11-2016 AUP74_RS15320 5f740325ca65fc71711c6deaff313fcd 217 Pfam PF05191 Adenylate kinase, active site lid 123 158 7.9E-16 T 11-11-2016 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219 AUP74_RS15320 5f740325ca65fc71711c6deaff313fcd 217 SUPERFAMILY SSF52540 1 216 1.2E-44 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS15320 5f740325ca65fc71711c6deaff313fcd 217 Gene3D G3DSA:3.40.50.300 1 215 2.1E-79 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS14680 8ae3d17534648a1e2520fc01442a912f 457 Pfam PF14793 Domain of unknown function (DUF4478) 9 116 7.5E-44 T 11-11-2016 IPR027820 Domain of unknown function DUF4478 AUP74_RS14680 8ae3d17534648a1e2520fc01442a912f 457 Pfam PF03641 Possible lysine decarboxylase 192 331 2.3E-32 T 11-11-2016 IPR031100 LOG family AUP74_RS14680 8ae3d17534648a1e2520fc01442a912f 457 Pfam PF11892 Domain of unknown function (DUF3412) 335 454 7.4E-56 T 11-11-2016 IPR021826 Protein of unknown function DUF3412 AUP74_RS14680 8ae3d17534648a1e2520fc01442a912f 457 SUPERFAMILY SSF102405 129 331 1.18E-40 T 11-11-2016 AUP74_RS14680 8ae3d17534648a1e2520fc01442a912f 457 Gene3D G3DSA:3.40.50.450 129 454 3.7E-118 T 11-11-2016 AUP74_RS14680 8ae3d17534648a1e2520fc01442a912f 457 Gene3D G3DSA:3.30.1850.10 7 117 1.5E-45 T 11-11-2016 IPR027820 Domain of unknown function DUF4478 AUP74_RS16085 0813cffa91d747c358ca7991600f87e6 225 Gene3D G3DSA:3.20.20.70 1 202 9.4E-69 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS16085 0813cffa91d747c358ca7991600f87e6 225 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 1 203 40.671 T 11-11-2016 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 AUP74_RS16085 0813cffa91d747c358ca7991600f87e6 225 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 3 198 1.8E-44 T 11-11-2016 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 AUP74_RS16085 0813cffa91d747c358ca7991600f87e6 225 SUPERFAMILY SSF51366 1 201 2.35E-60 T 11-11-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 AUP74_RS04520 ebc1e17f2dcd832273b22db116be94ce 185 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 3 144 4.4E-40 T 11-11-2016 IPR006543 Histidinol-phosphate phosphatase GO:0016791 AUP74_RS04520 ebc1e17f2dcd832273b22db116be94ce 185 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 3 146 5.1E-30 T 11-11-2016 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 AUP74_RS04520 ebc1e17f2dcd832273b22db116be94ce 185 Gene3D G3DSA:3.40.50.1000 1 177 9.9E-51 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS04520 ebc1e17f2dcd832273b22db116be94ce 185 PIRSF PIRSF004682 1 175 4.6E-49 T 11-11-2016 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 AUP74_RS04520 ebc1e17f2dcd832273b22db116be94ce 185 Pfam PF13242 HAD-hyrolase-like 99 174 3.3E-11 T 11-11-2016 AUP74_RS04520 ebc1e17f2dcd832273b22db116be94ce 185 SUPERFAMILY SSF56784 2 181 2.81E-41 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS10060 0dabed0b1c3d203404dff88e6a4521dd 423 Gene3D G3DSA:3.40.50.620 15 165 1.4E-14 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS10060 0dabed0b1c3d203404dff88e6a4521dd 423 Pfam PF01171 PP-loop family 15 185 1.2E-55 T 11-11-2016 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 AUP74_RS10060 0dabed0b1c3d203404dff88e6a4521dd 423 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 346 390 5.4E-16 T 11-11-2016 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 AUP74_RS10060 0dabed0b1c3d203404dff88e6a4521dd 423 Pfam PF11734 TilS substrate C-terminal domain 346 409 1.8E-22 T 11-11-2016 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 AUP74_RS10060 0dabed0b1c3d203404dff88e6a4521dd 423 SUPERFAMILY SSF82829 232 308 2.2E-17 T 11-11-2016 AUP74_RS10060 0dabed0b1c3d203404dff88e6a4521dd 423 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 1 296 24.35 T 11-11-2016 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 AUP74_RS10060 0dabed0b1c3d203404dff88e6a4521dd 423 SUPERFAMILY SSF52402 12 217 1.12E-58 T 11-11-2016 AUP74_RS10060 0dabed0b1c3d203404dff88e6a4521dd 423 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 15 189 1.1E-53 T 11-11-2016 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 AUP74_RS10060 0dabed0b1c3d203404dff88e6a4521dd 423 Pfam PF09179 TilS substrate binding domain 239 304 8.2E-15 T 11-11-2016 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 AUP74_RS10060 0dabed0b1c3d203404dff88e6a4521dd 423 SMART SM00977 345 416 1.4E-21 T 11-11-2016 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 AUP74_RS10060 0dabed0b1c3d203404dff88e6a4521dd 423 SUPERFAMILY SSF56037 313 411 6.28E-22 T 11-11-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 AUP74_RS12055 7a976acad235d53553943f66b4a7e91f 375 Pfam PF00285 Citrate synthase, C-terminal domain 10 356 6.7E-119 T 11-11-2016 IPR002020 Citrate synthase GO:0046912 AUP74_RS12055 7a976acad235d53553943f66b4a7e91f 375 PRINTS PR00143 Citrate synthase signature 197 225 1.7E-38 T 11-11-2016 IPR002020 Citrate synthase GO:0046912 AUP74_RS12055 7a976acad235d53553943f66b4a7e91f 375 PRINTS PR00143 Citrate synthase signature 125 138 1.7E-38 T 11-11-2016 IPR002020 Citrate synthase GO:0046912 AUP74_RS12055 7a976acad235d53553943f66b4a7e91f 375 PRINTS PR00143 Citrate synthase signature 175 190 1.7E-38 T 11-11-2016 IPR002020 Citrate synthase GO:0046912 AUP74_RS12055 7a976acad235d53553943f66b4a7e91f 375 PRINTS PR00143 Citrate synthase signature 327 341 1.7E-38 T 11-11-2016 IPR002020 Citrate synthase GO:0046912 AUP74_RS12055 7a976acad235d53553943f66b4a7e91f 375 PRINTS PR00143 Citrate synthase signature 307 323 1.7E-38 T 11-11-2016 IPR002020 Citrate synthase GO:0046912 AUP74_RS12055 7a976acad235d53553943f66b4a7e91f 375 PRINTS PR00143 Citrate synthase signature 250 270 1.7E-38 T 11-11-2016 IPR002020 Citrate synthase GO:0046912 AUP74_RS12055 7a976acad235d53553943f66b4a7e91f 375 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 10 374 4.4E-158 T 11-11-2016 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 AUP74_RS12055 7a976acad235d53553943f66b4a7e91f 375 ProSitePatterns PS00480 Citrate synthase signature. 257 269 - T 11-11-2016 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 AUP74_RS12055 7a976acad235d53553943f66b4a7e91f 375 SUPERFAMILY SSF48256 9 374 2.22E-129 T 11-11-2016 IPR002020 Citrate synthase GO:0046912 AUP74_RS12055 7a976acad235d53553943f66b4a7e91f 375 Gene3D G3DSA:1.10.230.10 235 321 2.9E-28 T 11-11-2016 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 AUP74_RS12055 7a976acad235d53553943f66b4a7e91f 375 Gene3D G3DSA:1.10.580.10 16 234 1.2E-79 T 11-11-2016 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 AUP74_RS12055 7a976acad235d53553943f66b4a7e91f 375 PIRSF PIRSF001369 2 375 1.5E-119 T 11-11-2016 IPR024176 Citrate synthase, bacterial-type AUP74_RS11490 b8e0fa6df38e5cc12fee1e49fab3d640 121 Gene3D G3DSA:2.40.50.140 21 103 2.7E-4 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS11490 b8e0fa6df38e5cc12fee1e49fab3d640 121 SUPERFAMILY SSF50249 33 104 1.48E-6 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS14685 42c9ef1c3736f9073598f93b31ddeb69 506 SUPERFAMILY SSF55073 292 472 2.35E-55 T 11-11-2016 IPR029787 Nucleotide cyclase AUP74_RS14685 42c9ef1c3736f9073598f93b31ddeb69 506 Pfam PF00672 HAMP domain 191 257 8.5E-16 T 11-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 AUP74_RS14685 42c9ef1c3736f9073598f93b31ddeb69 506 SUPERFAMILY SSF158472 210 258 4.58E-10 T 11-11-2016 AUP74_RS14685 42c9ef1c3736f9073598f93b31ddeb69 506 Gene3D G3DSA:3.30.70.1230 294 474 1.4E-48 T 11-11-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 AUP74_RS14685 42c9ef1c3736f9073598f93b31ddeb69 506 SMART SM00044 258 454 1.7E-19 T 11-11-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 AUP74_RS14685 42c9ef1c3736f9073598f93b31ddeb69 506 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 294 467 9.6E-35 T 11-11-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 AUP74_RS14685 42c9ef1c3736f9073598f93b31ddeb69 506 SMART SM00304 210 262 1.2E-9 T 11-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 AUP74_RS05930 4cbe35952acfef8269381b3cf5697f06 914 SUPERFAMILY SSF50249 149 248 3.56E-16 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS05930 4cbe35952acfef8269381b3cf5697f06 914 Pfam PF00773 RNB domain 271 601 1.9E-106 T 11-11-2016 AUP74_RS05930 4cbe35952acfef8269381b3cf5697f06 914 SMART SM00316 670 753 7.9E-13 T 11-11-2016 IPR022967 RNA-binding domain, S1 AUP74_RS05930 4cbe35952acfef8269381b3cf5697f06 914 Pfam PF08206 Ribonuclease B OB domain 98 155 1.9E-18 T 11-11-2016 IPR013223 Ribonuclease B, N-terminal OB domain AUP74_RS05930 4cbe35952acfef8269381b3cf5697f06 914 SMART SM00955 271 603 8.9E-185 T 11-11-2016 AUP74_RS05930 4cbe35952acfef8269381b3cf5697f06 914 SUPERFAMILY SSF50249 231 670 5.14E-148 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS05930 4cbe35952acfef8269381b3cf5697f06 914 SUPERFAMILY SSF50249 672 751 2.36E-21 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS05930 4cbe35952acfef8269381b3cf5697f06 914 Hamap MF_01895 Ribonuclease R [rnr]. 49 753 56.923 T 11-11-2016 IPR011805 Ribonuclease R GO:0003723|GO:0004518 AUP74_RS05930 4cbe35952acfef8269381b3cf5697f06 914 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 91 750 2.5E-222 T 11-11-2016 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 AUP74_RS05930 4cbe35952acfef8269381b3cf5697f06 914 Gene3D G3DSA:2.40.50.140 672 762 5.8E-20 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS05930 4cbe35952acfef8269381b3cf5697f06 914 ProSitePatterns PS01175 Ribonuclease II family signature. 570 594 - T 11-11-2016 IPR022966 Ribonuclease II/R, conserved site AUP74_RS05930 4cbe35952acfef8269381b3cf5697f06 914 SUPERFAMILY SSF50249 79 158 3.36E-16 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS05930 4cbe35952acfef8269381b3cf5697f06 914 SMART SM00357 97 156 2.2E-13 T 11-11-2016 IPR011129 Cold shock protein GO:0003676 AUP74_RS05930 4cbe35952acfef8269381b3cf5697f06 914 TIGRFAM TIGR02063 RNase_R: ribonuclease R 30 753 1.1E-259 T 11-11-2016 IPR011805 Ribonuclease R GO:0003723|GO:0004518 AUP74_RS05930 4cbe35952acfef8269381b3cf5697f06 914 Pfam PF00575 S1 RNA binding domain 671 750 1.7E-11 T 11-11-2016 IPR003029 S1 domain GO:0003676 AUP74_RS08275 0db9674f38523bd694274e21bdaf570e 985 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 875 985 1.9E-18 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS08275 0db9674f38523bd694274e21bdaf570e 985 PRINTS PR00344 Bacterial sensor protein C-terminal signature 930 940 1.3E-15 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS08275 0db9674f38523bd694274e21bdaf570e 985 PRINTS PR00344 Bacterial sensor protein C-terminal signature 971 984 1.3E-15 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS08275 0db9674f38523bd694274e21bdaf570e 985 PRINTS PR00344 Bacterial sensor protein C-terminal signature 912 926 1.3E-15 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS08275 0db9674f38523bd694274e21bdaf570e 985 PRINTS PR00344 Bacterial sensor protein C-terminal signature 943 961 1.3E-15 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS08275 0db9674f38523bd694274e21bdaf570e 985 Gene3D G3DSA:1.10.287.130 762 826 1.7E-7 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS08275 0db9674f38523bd694274e21bdaf570e 985 Pfam PF00512 His Kinase A (phospho-acceptor) domain 767 829 3.8E-9 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS08275 0db9674f38523bd694274e21bdaf570e 985 SMART SM00091 637 705 7.0E-4 T 11-11-2016 IPR000014 PAS domain AUP74_RS08275 0db9674f38523bd694274e21bdaf570e 985 SMART SM00388 766 831 4.2E-7 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS08275 0db9674f38523bd694274e21bdaf570e 985 SMART SM00387 875 985 1.7E-31 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS08275 0db9674f38523bd694274e21bdaf570e 985 Pfam PF00989 PAS fold 640 682 2.6E-5 T 11-11-2016 IPR013767 PAS fold GO:0006355 AUP74_RS08275 0db9674f38523bd694274e21bdaf570e 985 SUPERFAMILY SSF55785 629 721 7.04E-8 T 11-11-2016 IPR000014 PAS domain AUP74_RS08275 0db9674f38523bd694274e21bdaf570e 985 SUPERFAMILY SSF47384 762 829 1.71E-9 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS08275 0db9674f38523bd694274e21bdaf570e 985 Gene3D G3DSA:3.30.565.10 836 985 2.3E-39 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS08275 0db9674f38523bd694274e21bdaf570e 985 SUPERFAMILY SSF55874 831 985 5.5E-40 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS08275 0db9674f38523bd694274e21bdaf570e 985 Gene3D G3DSA:3.30.450.20 631 688 5.6E-8 T 11-11-2016 AUP74_RS08275 0db9674f38523bd694274e21bdaf570e 985 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 639 758 6.1E-8 T 11-11-2016 IPR000014 PAS domain AUP74_RS05685 c76bbe0665ae6ff83724f0da0dcbef6d 318 SUPERFAMILY SSF52440 5 123 3.16E-38 T 11-11-2016 IPR016185 Pre-ATP-grasp domain AUP74_RS05685 c76bbe0665ae6ff83724f0da0dcbef6d 318 Gene3D G3DSA:3.30.1490.20 140 192 1.3E-24 T 11-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 AUP74_RS05685 c76bbe0665ae6ff83724f0da0dcbef6d 318 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 125 297 4.0E-74 T 11-11-2016 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 AUP74_RS05685 c76bbe0665ae6ff83724f0da0dcbef6d 318 Gene3D G3DSA:3.40.50.20 5 130 6.8E-46 T 11-11-2016 IPR016185 Pre-ATP-grasp domain AUP74_RS05685 c76bbe0665ae6ff83724f0da0dcbef6d 318 Hamap MF_00162 Glutathione synthetase [gshB]. 1 317 159.836 T 11-11-2016 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 AUP74_RS05685 c76bbe0665ae6ff83724f0da0dcbef6d 318 Gene3D G3DSA:3.30.470.20 193 301 3.5E-49 T 11-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 AUP74_RS05685 c76bbe0665ae6ff83724f0da0dcbef6d 318 Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain 5 121 2.1E-38 T 11-11-2016 IPR004215 Prokaryotic glutathione synthetase, N-terminal GO:0004363|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 AUP74_RS05685 c76bbe0665ae6ff83724f0da0dcbef6d 318 TIGRFAM TIGR01380 glut_syn: glutathione synthase 5 312 7.0E-125 T 11-11-2016 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 AUP74_RS05685 c76bbe0665ae6ff83724f0da0dcbef6d 318 SUPERFAMILY SSF56059 124 314 1.04E-57 T 11-11-2016 AUP74_RS15185 023ba0ae77cdedae7e7a0aa0e7b41c49 346 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 159 171 - T 11-11-2016 IPR033140 Lipase, GDXG, putative serine active site AUP74_RS15185 023ba0ae77cdedae7e7a0aa0e7b41c49 346 Gene3D G3DSA:3.40.50.1820 58 327 1.5E-52 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS15185 023ba0ae77cdedae7e7a0aa0e7b41c49 346 Pfam PF07859 alpha/beta hydrolase fold 88 289 2.9E-27 T 11-11-2016 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 AUP74_RS15185 023ba0ae77cdedae7e7a0aa0e7b41c49 346 SUPERFAMILY SSF53474 38 297 1.54E-46 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS05990 1dab56cf3945ae452c56f116ed95ffeb 640 SUPERFAMILY SSF50621 462 567 4.66E-6 T 11-11-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AUP74_RS05990 1dab56cf3945ae452c56f116ed95ffeb 640 Gene3D G3DSA:2.40.37.10 337 362 1.6E-11 T 11-11-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AUP74_RS05990 1dab56cf3945ae452c56f116ed95ffeb 640 Gene3D G3DSA:2.40.37.10 458 572 1.6E-11 T 11-11-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AUP74_RS05990 1dab56cf3945ae452c56f116ed95ffeb 640 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 100 349 6.3E-37 T 11-11-2016 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 AUP74_RS05990 1dab56cf3945ae452c56f116ed95ffeb 640 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 128 140 3.2E-16 T 11-11-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AUP74_RS05990 1dab56cf3945ae452c56f116ed95ffeb 640 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 245 258 3.2E-16 T 11-11-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AUP74_RS05990 1dab56cf3945ae452c56f116ed95ffeb 640 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 104 122 3.2E-16 T 11-11-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AUP74_RS05990 1dab56cf3945ae452c56f116ed95ffeb 640 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 545 558 3.2E-16 T 11-11-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AUP74_RS05990 1dab56cf3945ae452c56f116ed95ffeb 640 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 339 358 3.2E-16 T 11-11-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AUP74_RS05990 1dab56cf3945ae452c56f116ed95ffeb 640 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 444 564 3.5E-24 T 11-11-2016 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 AUP74_RS05990 1dab56cf3945ae452c56f116ed95ffeb 640 PRINTS PR01180 Arginine decarboxylase signature 178 199 2.8E-59 T 11-11-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AUP74_RS05990 1dab56cf3945ae452c56f116ed95ffeb 640 PRINTS PR01180 Arginine decarboxylase signature 329 346 2.8E-59 T 11-11-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AUP74_RS05990 1dab56cf3945ae452c56f116ed95ffeb 640 PRINTS PR01180 Arginine decarboxylase signature 152 167 2.8E-59 T 11-11-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AUP74_RS05990 1dab56cf3945ae452c56f116ed95ffeb 640 PRINTS PR01180 Arginine decarboxylase signature 202 224 2.8E-59 T 11-11-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AUP74_RS05990 1dab56cf3945ae452c56f116ed95ffeb 640 PRINTS PR01180 Arginine decarboxylase signature 467 488 2.8E-59 T 11-11-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AUP74_RS05990 1dab56cf3945ae452c56f116ed95ffeb 640 PRINTS PR01180 Arginine decarboxylase signature 492 517 2.8E-59 T 11-11-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AUP74_RS05990 1dab56cf3945ae452c56f116ed95ffeb 640 PRINTS PR01180 Arginine decarboxylase signature 545 566 2.8E-59 T 11-11-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AUP74_RS05990 1dab56cf3945ae452c56f116ed95ffeb 640 PRINTS PR01180 Arginine decarboxylase signature 96 110 2.8E-59 T 11-11-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AUP74_RS05990 1dab56cf3945ae452c56f116ed95ffeb 640 Gene3D G3DSA:3.20.20.10 77 336 3.3E-48 T 11-11-2016 IPR029066 PLP-binding barrel AUP74_RS05990 1dab56cf3945ae452c56f116ed95ffeb 640 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 104 122 - T 11-11-2016 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site AUP74_RS05990 1dab56cf3945ae452c56f116ed95ffeb 640 PIRSF PIRSF001336 1 640 1.2E-241 T 11-11-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AUP74_RS05990 1dab56cf3945ae452c56f116ed95ffeb 640 SUPERFAMILY SSF51419 74 351 6.17E-55 T 11-11-2016 IPR029066 PLP-binding barrel AUP74_RS05990 1dab56cf3945ae452c56f116ed95ffeb 640 TIGRFAM TIGR01273 speA: arginine decarboxylase 9 638 2.1E-208 T 11-11-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AUP74_RS06565 0c3fc43590ce906bc32e77e10f364f01 197 Pfam PF01694 Rhomboid family 38 187 4.2E-27 T 11-11-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 AUP74_RS06565 0c3fc43590ce906bc32e77e10f364f01 197 Gene3D G3DSA:1.20.1540.10 10 189 1.1E-35 T 11-11-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 AUP74_RS06565 0c3fc43590ce906bc32e77e10f364f01 197 SUPERFAMILY SSF144091 9 194 3.27E-33 T 11-11-2016 AUP74_RS01580 15d1d1f1e7e1b229ea1b425442210d54 422 Pfam PF00464 Serine hydroxymethyltransferase 9 386 1.0E-185 T 11-11-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AUP74_RS01580 15d1d1f1e7e1b229ea1b425442210d54 422 Gene3D G3DSA:3.90.1150.10 286 420 6.0E-53 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS01580 15d1d1f1e7e1b229ea1b425442210d54 422 Gene3D G3DSA:3.40.640.10 37 285 8.1E-112 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AUP74_RS01580 15d1d1f1e7e1b229ea1b425442210d54 422 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 222 238 - T 11-11-2016 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0004372|GO:0006544|GO:0006563|GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AUP74_RS01580 15d1d1f1e7e1b229ea1b425442210d54 422 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 420 54.162 T 11-11-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AUP74_RS01580 15d1d1f1e7e1b229ea1b425442210d54 422 SUPERFAMILY SSF53383 7 419 6.46E-187 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase AUP74_RS01580 15d1d1f1e7e1b229ea1b425442210d54 422 PIRSF PIRSF000412 2 422 9.4E-170 T 11-11-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AUP74_RS13185 bf5216d9f3960decb12cbe14a3545917 362 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 295 324 - T 11-11-2016 IPR030390 RNA methyltransferase TrmA, active site AUP74_RS13185 bf5216d9f3960decb12cbe14a3545917 362 Gene3D G3DSA:3.40.50.150 152 361 1.3E-45 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS13185 bf5216d9f3960decb12cbe14a3545917 362 SUPERFAMILY SSF53335 10 361 2.31E-52 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS13185 bf5216d9f3960decb12cbe14a3545917 362 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 10 362 5.8E-160 T 11-11-2016 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 AUP74_RS13185 bf5216d9f3960decb12cbe14a3545917 362 Hamap MF_01011 tRNA/tmRNA (uracil-C(5))-methyltransferase [trmA]. 4 362 41.551 T 11-11-2016 IPR011869 tRNA/tmRNA (uracil-C(5))-methyltransferase, TrmA GO:0006396|GO:0030697 AUP74_RS13185 bf5216d9f3960decb12cbe14a3545917 362 TIGRFAM TIGR02143 trmA_only: tRNA (uracil(54)-C(5))-methyltransferase 10 362 8.5E-161 T 11-11-2016 IPR011869 tRNA/tmRNA (uracil-C(5))-methyltransferase, TrmA GO:0006396|GO:0030697 AUP74_RS13185 bf5216d9f3960decb12cbe14a3545917 362 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 344 354 - T 11-11-2016 IPR030391 RNA methyltransferase TrmA, conserved site AUP74_RS13600 355bfed47dac7ecada5b6e0e61085a80 559 SMART SM00919 269 525 1.6E-118 T 11-11-2016 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 AUP74_RS13600 355bfed47dac7ecada5b6e0e61085a80 559 SMART SM01274 79 259 3.5E-105 T 11-11-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 AUP74_RS13600 355bfed47dac7ecada5b6e0e61085a80 559 SUPERFAMILY SSF53223 5 268 1.65E-108 T 11-11-2016 AUP74_RS13600 355bfed47dac7ecada5b6e0e61085a80 559 Pfam PF00390 Malic enzyme, N-terminal domain 79 259 4.7E-77 T 11-11-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 AUP74_RS13600 355bfed47dac7ecada5b6e0e61085a80 559 Gene3D G3DSA:3.40.50.10380 15 266 3.7E-116 T 11-11-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 AUP74_RS13600 355bfed47dac7ecada5b6e0e61085a80 559 PIRSF PIRSF000106 1 557 1.8E-220 T 11-11-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 AUP74_RS13600 355bfed47dac7ecada5b6e0e61085a80 559 ProSitePatterns PS00331 Malic enzymes signature. 265 281 - T 11-11-2016 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 AUP74_RS13600 355bfed47dac7ecada5b6e0e61085a80 559 PRINTS PR00072 Malic enzyme signature 240 258 9.7E-73 T 11-11-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 AUP74_RS13600 355bfed47dac7ecada5b6e0e61085a80 559 PRINTS PR00072 Malic enzyme signature 85 109 9.7E-73 T 11-11-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 AUP74_RS13600 355bfed47dac7ecada5b6e0e61085a80 559 PRINTS PR00072 Malic enzyme signature 265 281 9.7E-73 T 11-11-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 AUP74_RS13600 355bfed47dac7ecada5b6e0e61085a80 559 PRINTS PR00072 Malic enzyme signature 145 174 9.7E-73 T 11-11-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 AUP74_RS13600 355bfed47dac7ecada5b6e0e61085a80 559 PRINTS PR00072 Malic enzyme signature 181 203 9.7E-73 T 11-11-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 AUP74_RS13600 355bfed47dac7ecada5b6e0e61085a80 559 PRINTS PR00072 Malic enzyme signature 296 312 9.7E-73 T 11-11-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 AUP74_RS13600 355bfed47dac7ecada5b6e0e61085a80 559 PRINTS PR00072 Malic enzyme signature 402 418 9.7E-73 T 11-11-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 AUP74_RS13600 355bfed47dac7ecada5b6e0e61085a80 559 SUPERFAMILY SSF51735 269 556 4.73E-92 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS13600 355bfed47dac7ecada5b6e0e61085a80 559 Pfam PF03949 Malic enzyme, NAD binding domain 269 524 1.5E-99 T 11-11-2016 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 AUP74_RS13600 355bfed47dac7ecada5b6e0e61085a80 559 Gene3D G3DSA:3.40.50.720 267 556 7.1E-105 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS03210 da780a8160116ba49eb19778e5a6983f 377 Pfam PF01551 Peptidase family M23 278 371 1.6E-23 T 11-11-2016 IPR016047 Peptidase M23 AUP74_RS03210 da780a8160116ba49eb19778e5a6983f 377 Gene3D G3DSA:1.10.287.950 17 109 4.1E-4 T 11-11-2016 AUP74_RS03210 da780a8160116ba49eb19778e5a6983f 377 SUPERFAMILY SSF51261 169 375 2.98E-43 T 11-11-2016 IPR011055 Duplicated hybrid motif AUP74_RS03210 da780a8160116ba49eb19778e5a6983f 377 Gene3D G3DSA:2.70.70.10 242 376 5.0E-35 T 11-11-2016 AUP74_RS16410 5b6f696bc671e438584a5751fe75f46f 337 Pfam PF01370 NAD dependent epimerase/dehydratase family 8 220 1.0E-25 T 11-11-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 AUP74_RS16410 5b6f696bc671e438584a5751fe75f46f 337 Gene3D G3DSA:3.40.50.720 7 322 8.3E-44 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS16410 5b6f696bc671e438584a5751fe75f46f 337 SUPERFAMILY SSF51735 295 327 1.51E-51 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS16410 5b6f696bc671e438584a5751fe75f46f 337 SUPERFAMILY SSF51735 7 266 1.51E-51 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS04805 f99e26f4df44828fc48fdb0ece219057 324 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 6 126 2.2E-30 T 11-11-2016 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AUP74_RS04805 f99e26f4df44828fc48fdb0ece219057 324 SUPERFAMILY SSF53271 76 315 1.74E-35 T 11-11-2016 IPR029057 Phosphoribosyltransferase-like AUP74_RS04805 f99e26f4df44828fc48fdb0ece219057 324 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 7 314 3.1E-68 T 11-11-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AUP74_RS04805 f99e26f4df44828fc48fdb0ece219057 324 Gene3D G3DSA:3.40.50.2020 3 166 1.4E-39 T 11-11-2016 IPR029057 Phosphoribosyltransferase-like AUP74_RS04805 f99e26f4df44828fc48fdb0ece219057 324 Pfam PF14572 Phosphoribosyl synthetase-associated domain 219 316 1.6E-15 T 11-11-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AUP74_RS04805 f99e26f4df44828fc48fdb0ece219057 324 SMART SM01400 6 126 4.1E-41 T 11-11-2016 AUP74_RS04805 f99e26f4df44828fc48fdb0ece219057 324 Gene3D G3DSA:3.40.50.2020 167 293 8.0E-31 T 11-11-2016 IPR029057 Phosphoribosyltransferase-like AUP74_RS16825 391a16a1960c2c7d2f048b49bf70e9b4 198 SUPERFAMILY SSF140478 26 176 1.31E-52 T 11-11-2016 IPR023353 LemA-like domain AUP74_RS16825 391a16a1960c2c7d2f048b49bf70e9b4 198 Pfam PF04011 LemA family 10 198 1.1E-63 T 11-11-2016 IPR007156 LemA AUP74_RS16825 391a16a1960c2c7d2f048b49bf70e9b4 198 Gene3D G3DSA:1.20.1440.20 15 198 2.8E-60 T 11-11-2016 IPR023353 LemA-like domain AUP74_RS11935 f01a4aff2cfede2eb150efc8a9642a2b 202 Hamap MF_00429 Na(+)-translocating NADH-quinone reductase subunit E [nqrE]. 1 202 29.391 T 11-11-2016 IPR010967 Na(+)-translocating NADH-quinone reductase subunit E GO:0009276|GO:0016021|GO:0016655|GO:0022904|GO:0055114 AUP74_RS11935 f01a4aff2cfede2eb150efc8a9642a2b 202 TIGRFAM TIGR01940 nqrE: NADH:ubiquinone oxidoreductase, Na(+)-translocating, E subunit 2 201 1.9E-105 T 11-11-2016 IPR010967 Na(+)-translocating NADH-quinone reductase subunit E GO:0009276|GO:0016021|GO:0016655|GO:0022904|GO:0055114 AUP74_RS11935 f01a4aff2cfede2eb150efc8a9642a2b 202 Pfam PF02508 Rnf-Nqr subunit, membrane protein 4 200 5.7E-61 T 11-11-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 AUP74_RS11935 f01a4aff2cfede2eb150efc8a9642a2b 202 PIRSF PIRSF006102 1 202 2.0E-62 T 11-11-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 AUP74_RS08550 947e03d2aa2494166871d8adeb14c3cb 717 SUPERFAMILY SSF53474 449 691 8.2E-50 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS08550 947e03d2aa2494166871d8adeb14c3cb 717 Gene3D G3DSA:2.130.10.120 105 439 7.9E-103 T 11-11-2016 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 AUP74_RS08550 947e03d2aa2494166871d8adeb14c3cb 717 Pfam PF00326 Prolyl oligopeptidase family 496 710 2.1E-68 T 11-11-2016 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 AUP74_RS08550 947e03d2aa2494166871d8adeb14c3cb 717 Gene3D G3DSA:3.40.50.1820 448 705 1.4E-47 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS08550 947e03d2aa2494166871d8adeb14c3cb 717 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 640 662 6.0E-62 T 11-11-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 AUP74_RS08550 947e03d2aa2494166871d8adeb14c3cb 717 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 507 531 6.0E-62 T 11-11-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 AUP74_RS08550 947e03d2aa2494166871d8adeb14c3cb 717 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 481 499 6.0E-62 T 11-11-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 AUP74_RS08550 947e03d2aa2494166871d8adeb14c3cb 717 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 565 585 6.0E-62 T 11-11-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 AUP74_RS08550 947e03d2aa2494166871d8adeb14c3cb 717 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 621 636 6.0E-62 T 11-11-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 AUP74_RS08550 947e03d2aa2494166871d8adeb14c3cb 717 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 535 554 6.0E-62 T 11-11-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 AUP74_RS08550 947e03d2aa2494166871d8adeb14c3cb 717 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 40 439 1.3E-129 T 11-11-2016 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 AUP74_RS08550 947e03d2aa2494166871d8adeb14c3cb 717 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 542 572 - T 11-11-2016 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 AUP74_RS08550 947e03d2aa2494166871d8adeb14c3cb 717 SUPERFAMILY SSF50993 34 445 1.12E-100 T 11-11-2016 AUP74_RS13355 2b5499904395043486d891c28252c9a3 394 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 346 365 - T 11-11-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AUP74_RS13355 2b5499904395043486d891c28252c9a3 394 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 241 386 4.0E-24 T 11-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AUP74_RS13355 2b5499904395043486d891c28252c9a3 394 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 136 227 4.4E-21 T 11-11-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 AUP74_RS13355 2b5499904395043486d891c28252c9a3 394 SUPERFAMILY SSF56645 9 239 1.57E-76 T 11-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 AUP74_RS13355 2b5499904395043486d891c28252c9a3 394 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 138 150 - T 11-11-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AUP74_RS13355 2b5499904395043486d891c28252c9a3 394 Gene3D G3DSA:1.20.140.10 240 392 1.8E-37 T 11-11-2016 AUP74_RS13355 2b5499904395043486d891c28252c9a3 394 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 21 132 2.8E-32 T 11-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 AUP74_RS13355 2b5499904395043486d891c28252c9a3 394 SUPERFAMILY SSF47203 243 392 5.15E-39 T 11-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AUP74_RS13355 2b5499904395043486d891c28252c9a3 394 Gene3D G3DSA:1.10.540.10 9 134 2.0E-42 T 11-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 AUP74_RS13355 2b5499904395043486d891c28252c9a3 394 Gene3D G3DSA:2.40.110.10 135 234 6.8E-33 T 11-11-2016 AUP74_RS06530 8c5ba20a0c39fbee83fe41004f94a4b9 601 Gene3D G3DSA:3.40.30.10 476 586 3.3E-18 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS06530 8c5ba20a0c39fbee83fe41004f94a4b9 601 Pfam PF11412 Disulphide bond corrector protein DsbC 43 156 1.4E-23 T 11-11-2016 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain AUP74_RS06530 8c5ba20a0c39fbee83fe41004f94a4b9 601 Gene3D G3DSA:2.60.40.1250 39 158 9.7E-30 T 11-11-2016 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain AUP74_RS06530 8c5ba20a0c39fbee83fe41004f94a4b9 601 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 198 373 2.4E-8 T 11-11-2016 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 AUP74_RS06530 8c5ba20a0c39fbee83fe41004f94a4b9 601 SUPERFAMILY SSF52833 475 587 1.71E-14 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS06530 8c5ba20a0c39fbee83fe41004f94a4b9 601 SUPERFAMILY SSF74863 41 157 2.22E-27 T 11-11-2016 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain AUP74_RS06530 8c5ba20a0c39fbee83fe41004f94a4b9 601 Pfam PF13899 Thioredoxin-like 476 561 1.7E-15 T 11-11-2016 AUP74_RS01165 b9c2aa8394ca7881dab06446968f2a24 730 Gene3D G3DSA:3.40.50.920 591 719 1.8E-25 T 11-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 AUP74_RS01165 b9c2aa8394ca7881dab06446968f2a24 730 Gene3D G3DSA:3.40.50.970 396 590 1.0E-58 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS01165 b9c2aa8394ca7881dab06446968f2a24 730 SUPERFAMILY SSF52518 399 599 6.35E-54 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS01165 b9c2aa8394ca7881dab06446968f2a24 730 Pfam PF00676 Dehydrogenase E1 component 37 347 2.1E-60 T 11-11-2016 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 AUP74_RS01165 b9c2aa8394ca7881dab06446968f2a24 730 Gene3D G3DSA:3.40.50.970 21 350 2.0E-103 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS01165 b9c2aa8394ca7881dab06446968f2a24 730 SMART SM00861 398 574 7.5E-40 T 11-11-2016 IPR005475 Transketolase-like, pyrimidine-binding domain AUP74_RS01165 b9c2aa8394ca7881dab06446968f2a24 730 Pfam PF02780 Transketolase, C-terminal domain 590 704 3.6E-19 T 11-11-2016 IPR033248 Transketolase, C-terminal domain AUP74_RS01165 b9c2aa8394ca7881dab06446968f2a24 730 SUPERFAMILY SSF52922 584 717 1.96E-22 T 11-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 AUP74_RS01165 b9c2aa8394ca7881dab06446968f2a24 730 Pfam PF02779 Transketolase, pyrimidine binding domain 402 573 3.1E-35 T 11-11-2016 IPR005475 Transketolase-like, pyrimidine-binding domain AUP74_RS01165 b9c2aa8394ca7881dab06446968f2a24 730 SUPERFAMILY SSF52518 33 351 9.5E-73 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS10000 dbf4a68616a0f781aad4134ce5a69abb 604 SUPERFAMILY SSF52540 346 589 8.49E-91 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS10000 dbf4a68616a0f781aad4134ce5a69abb 604 Pfam PF00005 ABC transporter 370 519 1.2E-36 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AUP74_RS10000 dbf4a68616a0f781aad4134ce5a69abb 604 ProSitePatterns PS00211 ABC transporters family signature. 491 505 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AUP74_RS10000 dbf4a68616a0f781aad4134ce5a69abb 604 Gene3D G3DSA:1.20.1560.10 19 345 2.9E-60 T 11-11-2016 AUP74_RS10000 dbf4a68616a0f781aad4134ce5a69abb 604 SMART SM00382 379 571 1.6E-16 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS10000 dbf4a68616a0f781aad4134ce5a69abb 604 Gene3D G3DSA:3.40.50.300 353 584 7.6E-82 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS10000 dbf4a68616a0f781aad4134ce5a69abb 604 Pfam PF00664 ABC transporter transmembrane region 32 307 7.8E-38 T 11-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 AUP74_RS10000 dbf4a68616a0f781aad4134ce5a69abb 604 SUPERFAMILY SSF90123 19 336 3.66E-59 T 11-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 AUP74_RS11820 80d4829c4e0036732a3b8dd12a60a8c5 82 Gene3D G3DSA:3.40.30.10 4 80 1.6E-20 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS11820 80d4829c4e0036732a3b8dd12a60a8c5 82 Pfam PF05768 Glutaredoxin-like domain (DUF836) 5 78 5.3E-14 T 11-11-2016 IPR008554 Glutaredoxin-like AUP74_RS11820 80d4829c4e0036732a3b8dd12a60a8c5 82 SUPERFAMILY SSF52833 5 79 6.83E-14 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS16415 27285b9e57b5c4c582b5bfcfdf09b885 158 SUPERFAMILY SSF51182 7 140 3.02E-22 T 11-11-2016 IPR011051 RmlC-like cupin domain AUP74_RS16415 27285b9e57b5c4c582b5bfcfdf09b885 158 Gene3D G3DSA:2.60.120.10 11 151 3.3E-40 T 11-11-2016 IPR014710 RmlC-like jelly roll fold AUP74_RS05650 98368beba7ef14345d518cb88fe57668 413 SUPERFAMILY SSF48452 95 204 1.11E-9 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS05650 98368beba7ef14345d518cb88fe57668 413 SUPERFAMILY SSF48452 335 386 1.11E-9 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS05650 98368beba7ef14345d518cb88fe57668 413 Gene3D G3DSA:1.25.40.10 90 389 9.9E-15 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS05650 98368beba7ef14345d518cb88fe57668 413 Pfam PF07219 HemY protein N-terminus 27 132 8.1E-24 T 11-11-2016 IPR010817 HemY, N-terminal AUP74_RS05650 98368beba7ef14345d518cb88fe57668 413 TIGRFAM TIGR00540 TPR_hemY_coli: heme biosynthesis-associated TPR protein 9 387 3.3E-93 T 11-11-2016 IPR005254 Heme biosynthesis-associated TPR protein GO:0016020|GO:0042168 AUP74_RS04235 04a4033acdbcc0545d45fd4e75a99fdb 1042 SUPERFAMILY SSF82714 716 799 3.14E-18 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS04235 04a4033acdbcc0545d45fd4e75a99fdb 1042 Pfam PF00873 AcrB/AcrD/AcrF family 6 1032 9.4E-242 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS04235 04a4033acdbcc0545d45fd4e75a99fdb 1042 SUPERFAMILY SSF82693 46 127 9.94E-21 T 11-11-2016 AUP74_RS04235 04a4033acdbcc0545d45fd4e75a99fdb 1042 SUPERFAMILY SSF82693 271 328 3.14E-22 T 11-11-2016 AUP74_RS04235 04a4033acdbcc0545d45fd4e75a99fdb 1042 SUPERFAMILY SSF82693 137 184 3.14E-22 T 11-11-2016 AUP74_RS04235 04a4033acdbcc0545d45fd4e75a99fdb 1042 Gene3D G3DSA:1.10.3850.10 806 1035 2.2E-54 T 11-11-2016 AUP74_RS04235 04a4033acdbcc0545d45fd4e75a99fdb 1042 Gene3D G3DSA:1.10.3850.10 276 500 4.5E-69 T 11-11-2016 AUP74_RS04235 04a4033acdbcc0545d45fd4e75a99fdb 1042 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1037 0.0 T 11-11-2016 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 AUP74_RS04235 04a4033acdbcc0545d45fd4e75a99fdb 1042 SUPERFAMILY SSF82866 294 499 8.63E-43 T 11-11-2016 AUP74_RS04235 04a4033acdbcc0545d45fd4e75a99fdb 1042 SUPERFAMILY SSF82866 798 1037 6.67E-50 T 11-11-2016 AUP74_RS04235 04a4033acdbcc0545d45fd4e75a99fdb 1042 SUPERFAMILY SSF82714 185 269 1.06E-17 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS04235 04a4033acdbcc0545d45fd4e75a99fdb 1042 Gene3D G3DSA:3.30.2090.10 716 804 2.6E-19 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS04235 04a4033acdbcc0545d45fd4e75a99fdb 1042 PRINTS PR00702 Acriflavin resistance protein family signature 334 357 1.0E-33 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS04235 04a4033acdbcc0545d45fd4e75a99fdb 1042 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 1.0E-33 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS04235 04a4033acdbcc0545d45fd4e75a99fdb 1042 PRINTS PR00702 Acriflavin resistance protein family signature 471 494 1.0E-33 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS04235 04a4033acdbcc0545d45fd4e75a99fdb 1042 PRINTS PR00702 Acriflavin resistance protein family signature 361 382 1.0E-33 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS04235 04a4033acdbcc0545d45fd4e75a99fdb 1042 PRINTS PR00702 Acriflavin resistance protein family signature 545 562 1.0E-33 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS04235 04a4033acdbcc0545d45fd4e75a99fdb 1042 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 1.0E-33 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS04235 04a4033acdbcc0545d45fd4e75a99fdb 1042 PRINTS PR00702 Acriflavin resistance protein family signature 389 413 1.0E-33 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS04235 04a4033acdbcc0545d45fd4e75a99fdb 1042 Gene3D G3DSA:3.30.70.1430 46 142 6.3E-25 T 11-11-2016 AUP74_RS04235 04a4033acdbcc0545d45fd4e75a99fdb 1042 Gene3D G3DSA:3.30.2090.10 185 269 1.0E-16 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS09190 1a73eb9886b4e919425017cf57e6da46 228 Gene3D G3DSA:2.40.30.70 1 151 2.9E-51 T 11-11-2016 IPR023370 TsaA-like domain AUP74_RS09190 1a73eb9886b4e919425017cf57e6da46 228 SUPERFAMILY SSF118196 2 219 5.89E-70 T 11-11-2016 IPR023370 TsaA-like domain AUP74_RS09190 1a73eb9886b4e919425017cf57e6da46 228 Pfam PF01980 Uncharacterised protein family UPF0066 17 138 1.8E-42 T 11-11-2016 IPR023370 TsaA-like domain AUP74_RS09190 1a73eb9886b4e919425017cf57e6da46 228 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 1 144 2.4E-42 T 11-11-2016 IPR023370 TsaA-like domain AUP74_RS13410 8ea757a9804345b17546ac741bbdfd69 114 PIRSF PIRSF029826 1 113 1.0E-31 T 11-11-2016 IPR011394 NTP Pyrophosphohydrolase MazG-related, RS21-C6 AUP74_RS13410 8ea757a9804345b17546ac741bbdfd69 114 SUPERFAMILY SSF101386 5 104 2.36E-24 T 11-11-2016 AUP74_RS13410 8ea757a9804345b17546ac741bbdfd69 114 Pfam PF12643 MazG-like family 31 110 2.8E-12 T 11-11-2016 IPR025984 MazG-like domain KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 AUP74_RS13410 8ea757a9804345b17546ac741bbdfd69 114 Gene3D G3DSA:1.10.287.1080 1 94 2.6E-19 T 11-11-2016 AUP74_RS16220 aa8f7ecddfbea26fda01b5cdc1b1ccbc 304 PRINTS PR00102 Ornithine carbamoyltransferase signature 120 134 2.1E-30 T 11-11-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AUP74_RS16220 aa8f7ecddfbea26fda01b5cdc1b1ccbc 304 PRINTS PR00102 Ornithine carbamoyltransferase signature 279 290 2.1E-30 T 11-11-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AUP74_RS16220 aa8f7ecddfbea26fda01b5cdc1b1ccbc 304 PRINTS PR00102 Ornithine carbamoyltransferase signature 80 93 2.1E-30 T 11-11-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AUP74_RS16220 aa8f7ecddfbea26fda01b5cdc1b1ccbc 304 PRINTS PR00102 Ornithine carbamoyltransferase signature 47 61 2.1E-30 T 11-11-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AUP74_RS16220 aa8f7ecddfbea26fda01b5cdc1b1ccbc 304 PRINTS PR00102 Ornithine carbamoyltransferase signature 216 226 2.1E-30 T 11-11-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AUP74_RS16220 aa8f7ecddfbea26fda01b5cdc1b1ccbc 304 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 4 299 1.2E-111 T 11-11-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AUP74_RS16220 aa8f7ecddfbea26fda01b5cdc1b1ccbc 304 SUPERFAMILY SSF53671 2 301 3.54E-101 T 11-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AUP74_RS16220 aa8f7ecddfbea26fda01b5cdc1b1ccbc 304 Gene3D G3DSA:3.40.50.1370 2 140 9.5E-57 T 11-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AUP74_RS16220 aa8f7ecddfbea26fda01b5cdc1b1ccbc 304 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 151 298 5.0E-46 T 11-11-2016 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 AUP74_RS16220 aa8f7ecddfbea26fda01b5cdc1b1ccbc 304 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 4 143 1.1E-50 T 11-11-2016 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 AUP74_RS16220 aa8f7ecddfbea26fda01b5cdc1b1ccbc 304 Gene3D G3DSA:3.40.50.1370 141 287 3.1E-52 T 11-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AUP74_RS16220 aa8f7ecddfbea26fda01b5cdc1b1ccbc 304 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 252 261 7.2E-17 T 11-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AUP74_RS16220 aa8f7ecddfbea26fda01b5cdc1b1ccbc 304 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 49 68 7.2E-17 T 11-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AUP74_RS16220 aa8f7ecddfbea26fda01b5cdc1b1ccbc 304 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 265 288 7.2E-17 T 11-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AUP74_RS16220 aa8f7ecddfbea26fda01b5cdc1b1ccbc 304 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 131 142 7.2E-17 T 11-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AUP74_RS16220 aa8f7ecddfbea26fda01b5cdc1b1ccbc 304 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 49 56 - T 11-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AUP74_RS16220 aa8f7ecddfbea26fda01b5cdc1b1ccbc 304 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 3 301 76.872 T 11-11-2016 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 AUP74_RS08175 f3e953dc9b4eb6af20bd39c5507f7d48 698 Gene3D G3DSA:2.170.130.10 21 145 4.9E-26 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS08175 f3e953dc9b4eb6af20bd39c5507f7d48 698 Gene3D G3DSA:2.40.170.20 146 695 8.2E-58 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS08175 f3e953dc9b4eb6af20bd39c5507f7d48 698 SUPERFAMILY SSF56935 18 695 8.06E-85 T 11-11-2016 AUP74_RS08175 f3e953dc9b4eb6af20bd39c5507f7d48 698 Pfam PF07715 TonB-dependent Receptor Plug Domain 42 145 1.4E-14 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS08175 f3e953dc9b4eb6af20bd39c5507f7d48 698 Pfam PF00593 TonB dependent receptor 450 694 3.6E-17 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS15080 4cff309c2d23257ce7b8a48a0db96ded 295 SUPERFAMILY SSF53850 92 289 2.26E-26 T 11-11-2016 AUP74_RS15080 4cff309c2d23257ce7b8a48a0db96ded 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 6.0E-9 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS15080 4cff309c2d23257ce7b8a48a0db96ded 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 6.0E-9 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS15080 4cff309c2d23257ce7b8a48a0db96ded 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 6.0E-9 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS15080 4cff309c2d23257ce7b8a48a0db96ded 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 1.5E-21 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS15080 4cff309c2d23257ce7b8a48a0db96ded 295 SUPERFAMILY SSF46785 2 85 2.85E-23 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS15080 4cff309c2d23257ce7b8a48a0db96ded 295 Gene3D G3DSA:1.10.10.10 4 83 1.0E-27 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS15080 4cff309c2d23257ce7b8a48a0db96ded 295 Gene3D G3DSA:3.40.190.10 199 257 1.1E-8 T 11-11-2016 AUP74_RS15080 4cff309c2d23257ce7b8a48a0db96ded 295 Pfam PF03466 LysR substrate binding domain 92 289 1.8E-23 T 11-11-2016 IPR005119 LysR, substrate-binding AUP74_RS15080 4cff309c2d23257ce7b8a48a0db96ded 295 Gene3D G3DSA:3.40.190.10 84 198 1.8E-11 T 11-11-2016 AUP74_RS03130 224c5761b24f5f71e9da46eafe84f0a0 254 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 251 5.1E-43 T 11-11-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 AUP74_RS03130 224c5761b24f5f71e9da46eafe84f0a0 254 SUPERFAMILY SSF52096 4 253 8.07E-62 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS03130 224c5761b24f5f71e9da46eafe84f0a0 254 Gene3D G3DSA:3.90.226.10 4 251 1.3E-58 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS00520 59f88e077b82d343f0deece4df43770e 230 SUPERFAMILY SSF51695 2 219 6.54E-21 T 11-11-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 AUP74_RS00520 59f88e077b82d343f0deece4df43770e 230 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 5 74 7.6E-6 T 11-11-2016 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 AUP74_RS00520 59f88e077b82d343f0deece4df43770e 230 Gene3D G3DSA:3.20.20.190 2 151 9.4E-14 T 11-11-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 AUP74_RS00015 4f9aee1fe9dda9653e95fede954463cd 241 Pfam PF00005 ABC transporter 20 166 1.7E-35 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AUP74_RS00015 4f9aee1fe9dda9653e95fede954463cd 241 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 215 236 3.5E-9 T 11-11-2016 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal AUP74_RS00015 4f9aee1fe9dda9653e95fede954463cd 241 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 4 240 1.2E-119 T 11-11-2016 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 AUP74_RS00015 4f9aee1fe9dda9653e95fede954463cd 241 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AUP74_RS00015 4f9aee1fe9dda9653e95fede954463cd 241 Gene3D G3DSA:3.40.50.300 4 235 1.1E-70 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS00015 4f9aee1fe9dda9653e95fede954463cd 241 SMART SM00382 28 237 8.1E-9 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS00015 4f9aee1fe9dda9653e95fede954463cd 241 SUPERFAMILY SSF52540 4 236 2.66E-65 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS15440 3ed4f9d98d6715e35578a9608e6b4496 317 Gene3D G3DSA:3.30.70.1400 10 94 1.7E-26 T 11-11-2016 AUP74_RS15440 3ed4f9d98d6715e35578a9608e6b4496 317 PIRSF PIRSF006487 1 304 5.1E-17 T 11-11-2016 IPR028896 Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 AUP74_RS15440 3ed4f9d98d6715e35578a9608e6b4496 317 Pfam PF01571 Aminomethyltransferase folate-binding domain 3 175 4.1E-15 T 11-11-2016 IPR006222 Glycine cleavage T-protein-like, N-terminal AUP74_RS15440 3ed4f9d98d6715e35578a9608e6b4496 317 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 177 241 1.3E-25 T 11-11-2016 IPR017703 YgfZ/GcvT conserved site AUP74_RS15440 3ed4f9d98d6715e35578a9608e6b4496 317 SUPERFAMILY SSF103025 3 231 2.98E-57 T 11-11-2016 AUP74_RS15440 3ed4f9d98d6715e35578a9608e6b4496 317 SUPERFAMILY SSF101790 234 309 3.2E-6 T 11-11-2016 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain AUP74_RS13840 d2ccd63edd963899ef2f9fbbe63e39cf 158 SUPERFAMILY SSF117070 8 152 2.35E-22 T 11-11-2016 AUP74_RS13840 d2ccd63edd963899ef2f9fbbe63e39cf 158 Gene3D G3DSA:2.60.40.10 42 104 4.5E-7 T 11-11-2016 IPR013783 Immunoglobulin-like fold AUP74_RS13840 d2ccd63edd963899ef2f9fbbe63e39cf 158 SMART SM00769 32 153 2.4E-8 T 11-11-2016 IPR013990 Water stress and hypersensitive response domain GO:0009269 AUP74_RS13840 d2ccd63edd963899ef2f9fbbe63e39cf 158 Pfam PF03168 Late embryogenesis abundant protein 53 139 6.2E-7 T 11-11-2016 IPR004864 Late embryogenesis abundant protein, LEA-14 AUP74_RS11975 29259b79d97b6a50f8295b96a0a80d3c 543 Gene3D G3DSA:2.30.38.10 339 418 8.9E-20 T 11-11-2016 AUP74_RS11975 29259b79d97b6a50f8295b96a0a80d3c 543 Gene3D G3DSA:3.40.50.980 13 186 5.0E-30 T 11-11-2016 AUP74_RS11975 29259b79d97b6a50f8295b96a0a80d3c 543 SUPERFAMILY SSF56801 9 524 5.63E-125 T 11-11-2016 AUP74_RS11975 29259b79d97b6a50f8295b96a0a80d3c 543 Gene3D G3DSA:3.30.300.30 422 523 1.8E-21 T 11-11-2016 AUP74_RS11975 29259b79d97b6a50f8295b96a0a80d3c 543 Pfam PF13193 AMP-binding enzyme C-terminal domain 436 513 4.2E-13 T 11-11-2016 IPR025110 AMP-binding enzyme C-terminal domain AUP74_RS11975 29259b79d97b6a50f8295b96a0a80d3c 543 Pfam PF00501 AMP-binding enzyme 19 427 1.2E-84 T 11-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 AUP74_RS11975 29259b79d97b6a50f8295b96a0a80d3c 543 ProSitePatterns PS00455 Putative AMP-binding domain signature. 181 192 - T 11-11-2016 IPR020845 AMP-binding, conserved site AUP74_RS11975 29259b79d97b6a50f8295b96a0a80d3c 543 Gene3D G3DSA:3.40.50.980 187 332 2.6E-31 T 11-11-2016 AUP74_RS00150 20e9723b27f73d38c37f516b37295b8f 300 SUPERFAMILY SSF160240 219 286 4.05E-11 T 11-11-2016 AUP74_RS00150 20e9723b27f73d38c37f516b37295b8f 300 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 16 286 7.8E-85 T 11-11-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AUP74_RS00150 20e9723b27f73d38c37f516b37295b8f 300 Gene3D G3DSA:1.20.1510.10 17 207 5.7E-57 T 11-11-2016 IPR027469 Cation efflux protein transmembrane domain AUP74_RS00150 20e9723b27f73d38c37f516b37295b8f 300 Pfam PF01545 Cation efflux family 19 207 6.0E-45 T 11-11-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AUP74_RS00150 20e9723b27f73d38c37f516b37295b8f 300 Gene3D G3DSA:3.30.70.1350 221 286 2.9E-5 T 11-11-2016 IPR027470 Cation efflux protein, cytoplasmic domain AUP74_RS00150 20e9723b27f73d38c37f516b37295b8f 300 SUPERFAMILY SSF161111 14 208 9.55E-53 T 11-11-2016 AUP74_RS09070 915d816474c67ccc7e4b357cc1f06d67 510 Pfam PF14402 7 transmembrane helices usually fused to an inactive transglutaminase 199 508 3.2E-133 T 11-11-2016 IPR025840 7 transmembrane helices usually fused to an inactive transglutaminase AUP74_RS09070 915d816474c67ccc7e4b357cc1f06d67 510 Pfam PF14400 Inactive transglutaminase fused to 7 transmembrane helices 24 185 3.3E-44 T 11-11-2016 IPR025838 Inactive transglutaminase fused to 7 transmembrane helices AUP74_RS10280 c14418bfc786d2e40051af404456e80c 64 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 48 1.0E-19 T 11-11-2016 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 AUP74_RS10280 c14418bfc786d2e40051af404456e80c 64 SUPERFAMILY SSF117130 1 54 1.1E-20 T 11-11-2016 AUP74_RS10280 c14418bfc786d2e40051af404456e80c 64 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 58 4.1E-30 T 11-11-2016 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 AUP74_RS10280 c14418bfc786d2e40051af404456e80c 64 Pfam PF02599 Global regulator protein family 1 52 3.0E-26 T 11-11-2016 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 AUP74_RS10280 c14418bfc786d2e40051af404456e80c 64 Hamap MF_00167 Carbon storage regulator [csrA]. 1 64 20.698 T 11-11-2016 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 AUP74_RS06650 d2a1c2335154ede5bc4c5c34618df20c 434 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 6 432 43.314 T 11-11-2016 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 AUP74_RS06650 d2a1c2335154ede5bc4c5c34618df20c 434 Pfam PF00579 tRNA synthetases class I (W and Y) 36 329 5.9E-84 T 11-11-2016 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS06650 d2a1c2335154ede5bc4c5c34618df20c 434 SUPERFAMILY SSF55174 327 432 2.75E-13 T 11-11-2016 AUP74_RS06650 d2a1c2335154ede5bc4c5c34618df20c 434 Gene3D G3DSA:3.10.290.10 323 432 8.8E-19 T 11-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 AUP74_RS06650 d2a1c2335154ede5bc4c5c34618df20c 434 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 189 211 1.3E-29 T 11-11-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AUP74_RS06650 d2a1c2335154ede5bc4c5c34618df20c 434 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 222 234 1.3E-29 T 11-11-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AUP74_RS06650 d2a1c2335154ede5bc4c5c34618df20c 434 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 47 69 1.3E-29 T 11-11-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AUP74_RS06650 d2a1c2335154ede5bc4c5c34618df20c 434 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 168 183 1.3E-29 T 11-11-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AUP74_RS06650 d2a1c2335154ede5bc4c5c34618df20c 434 SUPERFAMILY SSF52374 8 329 1.04E-95 T 11-11-2016 AUP74_RS06650 d2a1c2335154ede5bc4c5c34618df20c 434 Gene3D G3DSA:1.10.240.10 239 322 1.1E-39 T 11-11-2016 AUP74_RS06650 d2a1c2335154ede5bc4c5c34618df20c 434 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 6 428 2.4E-118 T 11-11-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AUP74_RS06650 d2a1c2335154ede5bc4c5c34618df20c 434 Gene3D G3DSA:3.40.50.620 6 238 5.5E-96 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS14000 fe3ee5881727f8bbcc5bcad1e4f39c0d 392 Gene3D G3DSA:1.20.1250.20 198 376 1.7E-10 T 11-11-2016 AUP74_RS14000 fe3ee5881727f8bbcc5bcad1e4f39c0d 392 Pfam PF07690 Major Facilitator Superfamily 15 317 8.8E-9 T 11-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AUP74_RS14000 fe3ee5881727f8bbcc5bcad1e4f39c0d 392 SUPERFAMILY SSF103473 7 376 9.55E-29 T 11-11-2016 IPR020846 Major facilitator superfamily domain AUP74_RS14000 fe3ee5881727f8bbcc5bcad1e4f39c0d 392 Gene3D G3DSA:1.20.1250.20 11 188 3.1E-12 T 11-11-2016 AUP74_RS04640 c31c64161724a544a9de8a10375e53b6 773 Pfam PF00593 TonB dependent receptor 485 771 7.3E-16 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS04640 c31c64161724a544a9de8a10375e53b6 773 Gene3D G3DSA:2.40.170.20 169 772 6.2E-74 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS04640 c31c64161724a544a9de8a10375e53b6 773 Pfam PF07715 TonB-dependent Receptor Plug Domain 52 159 2.0E-12 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS04640 c31c64161724a544a9de8a10375e53b6 773 Gene3D G3DSA:2.170.130.10 30 168 3.2E-29 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS04640 c31c64161724a544a9de8a10375e53b6 773 SUPERFAMILY SSF56935 657 772 1.34E-103 T 11-11-2016 AUP74_RS04640 c31c64161724a544a9de8a10375e53b6 773 SUPERFAMILY SSF56935 29 624 1.34E-103 T 11-11-2016 AUP74_RS01170 c53146eab4fd68f661541fd719972eff 463 Gene3D G3DSA:1.20.1250.20 7 196 5.5E-37 T 11-11-2016 AUP74_RS01170 c53146eab4fd68f661541fd719972eff 463 Pfam PF07690 Major Facilitator Superfamily 16 365 4.5E-45 T 11-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AUP74_RS01170 c53146eab4fd68f661541fd719972eff 463 SUPERFAMILY SSF103473 3 378 2.22E-61 T 11-11-2016 IPR020846 Major facilitator superfamily domain AUP74_RS01170 c53146eab4fd68f661541fd719972eff 463 SUPERFAMILY SSF103473 419 444 2.22E-61 T 11-11-2016 IPR020846 Major facilitator superfamily domain AUP74_RS01170 c53146eab4fd68f661541fd719972eff 463 Gene3D G3DSA:1.20.1250.20 420 433 7.3E-12 T 11-11-2016 AUP74_RS01170 c53146eab4fd68f661541fd719972eff 463 Gene3D G3DSA:1.20.1250.20 211 379 7.3E-12 T 11-11-2016 AUP74_RS13525 7654257e89d2029410896f93ed1175e3 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 15 127 1.7E-27 T 11-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 AUP74_RS13525 7654257e89d2029410896f93ed1175e3 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 131 225 7.5E-22 T 11-11-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 AUP74_RS13525 7654257e89d2029410896f93ed1175e3 387 Gene3D G3DSA:1.10.540.10 10 127 3.7E-33 T 11-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 AUP74_RS13525 7654257e89d2029410896f93ed1175e3 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 237 385 9.0E-42 T 11-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AUP74_RS13525 7654257e89d2029410896f93ed1175e3 387 SUPERFAMILY SSF47203 235 385 1.45E-40 T 11-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AUP74_RS13525 7654257e89d2029410896f93ed1175e3 387 Gene3D G3DSA:2.40.110.10 131 226 2.6E-36 T 11-11-2016 AUP74_RS13525 7654257e89d2029410896f93ed1175e3 387 SUPERFAMILY SSF56645 6 250 1.44E-73 T 11-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 AUP74_RS13525 7654257e89d2029410896f93ed1175e3 387 Gene3D G3DSA:1.20.140.10 227 385 4.8E-57 T 11-11-2016 AUP74_RS00010 214adeb2540191aed4ca7224b6a337d5 181 Gene3D G3DSA:2.60.450.10 25 161 4.0E-34 T 11-11-2016 AUP74_RS00010 214adeb2540191aed4ca7224b6a337d5 181 Hamap MF_01914 Lipopolysaccharide export system protein LptA [lptA]. 8 165 22.297 T 11-11-2016 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 AUP74_RS00010 214adeb2540191aed4ca7224b6a337d5 181 TIGRFAM TIGR03002 outer_YhbN_LptA: lipopolysaccharide transport periplasmic protein LptA 24 165 3.8E-43 T 11-11-2016 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 AUP74_RS00010 214adeb2540191aed4ca7224b6a337d5 181 Pfam PF03968 OstA-like protein 34 145 7.8E-27 T 11-11-2016 IPR005653 Organic solvent tolerance-like, N-terminal AUP74_RS00235 d1da86113355c2d77d0a06b1500db770 522 Pfam PF04820 Tryptophan halogenase 13 472 9.1E-132 T 11-11-2016 IPR006905 Tryptophan halogenase AUP74_RS00235 d1da86113355c2d77d0a06b1500db770 522 Gene3D G3DSA:3.50.50.60 331 375 2.4E-54 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS00235 d1da86113355c2d77d0a06b1500db770 522 Gene3D G3DSA:3.50.50.60 9 83 2.4E-54 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS00235 d1da86113355c2d77d0a06b1500db770 522 Gene3D G3DSA:3.50.50.60 165 245 2.4E-54 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS00235 d1da86113355c2d77d0a06b1500db770 522 SUPERFAMILY SSF51905 12 98 1.05E-33 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS00235 d1da86113355c2d77d0a06b1500db770 522 SUPERFAMILY SSF51905 156 247 1.05E-33 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS00235 d1da86113355c2d77d0a06b1500db770 522 SUPERFAMILY SSF51905 336 442 1.05E-33 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS00235 d1da86113355c2d77d0a06b1500db770 522 PIRSF PIRSF011396 5 519 1.5E-159 T 11-11-2016 IPR006905 Tryptophan halogenase AUP74_RS06525 1238a3cb1ad3d77d5201d21bb504242d 151 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 151 71.647 T 11-11-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AUP74_RS06525 1238a3cb1ad3d77d5201d21bb504242d 151 PIRSF PIRSF001399 1 147 2.2E-59 T 11-11-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AUP74_RS06525 1238a3cb1ad3d77d5201d21bb504242d 151 Pfam PF01220 Dehydroquinase class II 3 140 6.0E-60 T 11-11-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AUP74_RS06525 1238a3cb1ad3d77d5201d21bb504242d 151 ProSitePatterns PS01029 Dehydroquinase class II signature. 7 24 - T 11-11-2016 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AUP74_RS06525 1238a3cb1ad3d77d5201d21bb504242d 151 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 17 144 1.0E-42 T 11-11-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AUP74_RS06525 1238a3cb1ad3d77d5201d21bb504242d 151 Gene3D G3DSA:3.40.50.9100 2 144 4.9E-66 T 11-11-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AUP74_RS06525 1238a3cb1ad3d77d5201d21bb504242d 151 SUPERFAMILY SSF52304 3 146 2.88E-61 T 11-11-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AUP74_RS06525 1238a3cb1ad3d77d5201d21bb504242d 151 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 3 143 6.9E-58 T 11-11-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AUP74_RS05705 b2fd9bad440b016d8f4a00c868887370 714 SUPERFAMILY SSF58104 371 673 3.01E-66 T 11-11-2016 AUP74_RS05705 b2fd9bad440b016d8f4a00c868887370 714 Pfam PF13675 Type IV pili methyl-accepting chemotaxis transducer N-term 45 141 2.7E-9 T 11-11-2016 IPR029095 NarX-like, N-terminal AUP74_RS05705 b2fd9bad440b016d8f4a00c868887370 714 Gene3D G3DSA:1.10.287.950 422 639 1.1E-52 T 11-11-2016 AUP74_RS05705 b2fd9bad440b016d8f4a00c868887370 714 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 470 667 1.7E-49 T 11-11-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 AUP74_RS05705 b2fd9bad440b016d8f4a00c868887370 714 SMART SM00283 407 668 7.4E-94 T 11-11-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 AUP74_RS10670 9e7698ad5194a100c8ade0b9f3d609c7 860 ProSitePatterns PS00523 Sulfatases signature 1. 125 137 - T 11-11-2016 IPR024607 Sulfatase, conserved site AUP74_RS10670 9e7698ad5194a100c8ade0b9f3d609c7 860 Pfam PF00884 Sulfatase 81 519 8.7E-71 T 11-11-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 AUP74_RS10670 9e7698ad5194a100c8ade0b9f3d609c7 860 Gene3D G3DSA:3.40.720.10 80 546 6.5E-95 T 11-11-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 AUP74_RS10670 9e7698ad5194a100c8ade0b9f3d609c7 860 Gene3D G3DSA:3.30.1120.10 550 642 9.4E-19 T 11-11-2016 AUP74_RS10670 9e7698ad5194a100c8ade0b9f3d609c7 860 SUPERFAMILY SSF53649 81 636 1.96E-115 T 11-11-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 AUP74_RS06510 88cc526ea926afe5d384541ac83cf185 293 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 291 31.758 T 11-11-2016 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 AUP74_RS06510 88cc526ea926afe5d384541ac83cf185 293 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 3 291 1.5E-90 T 11-11-2016 AUP74_RS06510 88cc526ea926afe5d384541ac83cf185 293 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 285 1.5E-85 T 11-11-2016 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 AUP74_RS06510 88cc526ea926afe5d384541ac83cf185 293 Gene3D G3DSA:3.40.50.150 97 286 2.0E-38 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS06510 88cc526ea926afe5d384541ac83cf185 293 PIRSF PIRSF000401 1 293 6.0E-85 T 11-11-2016 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 AUP74_RS06510 88cc526ea926afe5d384541ac83cf185 293 SUPERFAMILY SSF53335 48 272 3.8E-40 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS00575 7f02df81046b33c04213b43e876adb7c 1313 Gene3D G3DSA:3.40.50.300 86 242 3.0E-48 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS00575 7f02df81046b33c04213b43e876adb7c 1313 Gene3D G3DSA:3.40.50.300 286 430 5.0E-13 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS00575 7f02df81046b33c04213b43e876adb7c 1313 SMART SM00487 84 268 3.1E-28 T 11-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain AUP74_RS00575 7f02df81046b33c04213b43e876adb7c 1313 Pfam PF00271 Helicase conserved C-terminal domain 290 414 1.1E-10 T 11-11-2016 IPR001650 Helicase, C-terminal AUP74_RS00575 7f02df81046b33c04213b43e876adb7c 1313 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 603 703 3.1E-18 T 11-11-2016 IPR011709 Domain of unknown function DUF1605 AUP74_RS00575 7f02df81046b33c04213b43e876adb7c 1313 SMART SM00847 475 565 1.8E-33 T 11-11-2016 IPR007502 Helicase-associated domain GO:0004386 AUP74_RS00575 7f02df81046b33c04213b43e876adb7c 1313 SUPERFAMILY SSF52540 83 599 3.51E-107 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS00575 7f02df81046b33c04213b43e876adb7c 1313 SMART SM00382 101 381 8.5E-5 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS00575 7f02df81046b33c04213b43e876adb7c 1313 Pfam PF04408 Helicase associated domain (HA2) 478 562 3.4E-18 T 11-11-2016 IPR007502 Helicase-associated domain GO:0004386 AUP74_RS00575 7f02df81046b33c04213b43e876adb7c 1313 SMART SM00490 315 415 7.3E-15 T 11-11-2016 IPR001650 Helicase, C-terminal AUP74_RS00575 7f02df81046b33c04213b43e876adb7c 1313 Pfam PF11898 Domain of unknown function (DUF3418) 718 1302 2.1E-195 T 11-11-2016 IPR024590 RNA helicase HrpA, C-terminal AUP74_RS00575 7f02df81046b33c04213b43e876adb7c 1313 Pfam PF00270 DEAD/DEAH box helicase 94 244 1.9E-6 T 11-11-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AUP74_RS00575 7f02df81046b33c04213b43e876adb7c 1313 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 21 1302 0.0 T 11-11-2016 IPR010222 RNA helicase HrpA GO:0004004 AUP74_RS08745 ca34fd43bc6f98cfca9d075b17f8bf04 143 Gene3D G3DSA:2.160.10.10 6 127 3.7E-38 T 11-11-2016 AUP74_RS08745 ca34fd43bc6f98cfca9d075b17f8bf04 143 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 73 107 9.9E-10 T 11-11-2016 IPR001451 Hexapeptide repeat AUP74_RS08745 ca34fd43bc6f98cfca9d075b17f8bf04 143 SUPERFAMILY SSF51161 5 129 4.85E-38 T 11-11-2016 IPR011004 Trimeric LpxA-like AUP74_RS02415 8502bdd355397305e67bcd9018993736 188 Pfam PF00571 CBS domain 41 84 9.7E-4 T 11-11-2016 IPR000644 CBS domain AUP74_RS02415 8502bdd355397305e67bcd9018993736 188 Gene3D G3DSA:3.10.580.10 31 105 5.4E-6 T 11-11-2016 AUP74_RS02415 8502bdd355397305e67bcd9018993736 188 SUPERFAMILY SSF54631 35 161 7.64E-12 T 11-11-2016 AUP74_RS02415 8502bdd355397305e67bcd9018993736 188 Gene3D G3DSA:3.10.580.10 106 168 9.8E-4 T 11-11-2016 AUP74_RS10445 ae358abc6875d80094bbb854e8b31202 274 Pfam PF03922 OmpW family 44 274 2.1E-16 T 11-11-2016 IPR005618 Outer membrane protein, OmpW GO:0019867 AUP74_RS10445 ae358abc6875d80094bbb854e8b31202 274 Gene3D G3DSA:2.40.160.20 43 274 8.0E-25 T 11-11-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AUP74_RS10445 ae358abc6875d80094bbb854e8b31202 274 SUPERFAMILY SSF56925 43 274 1.02E-12 T 11-11-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AUP74_RS10445 ae358abc6875d80094bbb854e8b31202 274 ProSitePatterns PS00695 Enterobacterial virulence outer membrane protein signature 2. 266 274 - T 11-11-2016 IPR000758 Virulence-related outer membrane protein GO:0009279 AUP74_RS03440 51daf01ca99a764541d0dce8916a258e 258 Pfam PF08447 PAS fold 58 153 1.2E-8 T 11-11-2016 IPR013655 PAS fold-3 GO:0005515 AUP74_RS03440 51daf01ca99a764541d0dce8916a258e 258 SMART SM00421 195 252 1.4E-16 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS03440 51daf01ca99a764541d0dce8916a258e 258 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 212 228 5.7E-11 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS03440 51daf01ca99a764541d0dce8916a258e 258 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 228 240 5.7E-11 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS03440 51daf01ca99a764541d0dce8916a258e 258 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 198 212 5.7E-11 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS03440 51daf01ca99a764541d0dce8916a258e 258 SUPERFAMILY SSF46894 194 257 8.16E-17 T 11-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AUP74_RS03440 51daf01ca99a764541d0dce8916a258e 258 ProSitePatterns PS00622 LuxR-type HTH domain signature. 212 239 - T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS03440 51daf01ca99a764541d0dce8916a258e 258 SUPERFAMILY SSF55785 53 157 1.43E-7 T 11-11-2016 IPR000014 PAS domain AUP74_RS03440 51daf01ca99a764541d0dce8916a258e 258 Pfam PF00196 Bacterial regulatory proteins, luxR family 197 249 8.0E-15 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS03440 51daf01ca99a764541d0dce8916a258e 258 Gene3D G3DSA:3.30.450.20 57 168 3.8E-20 T 11-11-2016 AUP74_RS03440 51daf01ca99a764541d0dce8916a258e 258 Gene3D G3DSA:1.10.10.10 198 257 1.6E-19 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS03440 51daf01ca99a764541d0dce8916a258e 258 SMART SM00091 33 100 9.6E-4 T 11-11-2016 IPR000014 PAS domain AUP74_RS04305 4aea4da1cc121887a0c5a3197dc5ef8d 295 SUPERFAMILY SSF46785 5 85 7.2E-18 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS04305 4aea4da1cc121887a0c5a3197dc5ef8d 295 Gene3D G3DSA:1.10.10.10 5 87 1.4E-21 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS04305 4aea4da1cc121887a0c5a3197dc5ef8d 295 Pfam PF03466 LysR substrate binding domain 93 289 1.9E-25 T 11-11-2016 IPR005119 LysR, substrate-binding AUP74_RS04305 4aea4da1cc121887a0c5a3197dc5ef8d 295 Gene3D G3DSA:3.40.190.10 172 254 3.5E-10 T 11-11-2016 AUP74_RS04305 4aea4da1cc121887a0c5a3197dc5ef8d 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 2.3E-17 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS04305 4aea4da1cc121887a0c5a3197dc5ef8d 295 SUPERFAMILY SSF53850 95 290 4.19E-27 T 11-11-2016 AUP74_RS04305 4aea4da1cc121887a0c5a3197dc5ef8d 295 Gene3D G3DSA:3.40.190.10 96 171 2.0E-5 T 11-11-2016 AUP74_RS16805 a9aab9a8b77f335dfbd4b8168e1ca44c 109 Hamap MF_00048 UPF0102 protein YraN [yraN]. 1 103 18.762 T 11-11-2016 IPR003509 Uncharacterised protein family UPF0102 AUP74_RS16805 a9aab9a8b77f335dfbd4b8168e1ca44c 109 SUPERFAMILY SSF52980 2 91 6.3E-22 T 11-11-2016 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AUP74_RS16805 a9aab9a8b77f335dfbd4b8168e1ca44c 109 Gene3D G3DSA:3.40.1350.10 2 108 2.4E-37 T 11-11-2016 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 Reactome: R-HSA-6784531 AUP74_RS16805 a9aab9a8b77f335dfbd4b8168e1ca44c 109 Pfam PF02021 Uncharacterised protein family UPF0102 2 90 1.4E-28 T 11-11-2016 IPR003509 Uncharacterised protein family UPF0102 AUP74_RS16805 a9aab9a8b77f335dfbd4b8168e1ca44c 109 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 2 109 5.8E-34 T 11-11-2016 IPR003509 Uncharacterised protein family UPF0102 AUP74_RS12730 57e9e83b2c006e58694efa7791e641e0 466 SUPERFAMILY SSF52540 87 358 1.18E-83 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS12730 57e9e83b2c006e58694efa7791e641e0 466 SUPERFAMILY SSF50615 10 85 4.32E-18 T 11-11-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AUP74_RS12730 57e9e83b2c006e58694efa7791e641e0 466 Gene3D G3DSA:2.40.10.170 7 85 9.7E-19 T 11-11-2016 AUP74_RS12730 57e9e83b2c006e58694efa7791e641e0 466 SUPERFAMILY SSF47917 356 463 1.49E-36 T 11-11-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AUP74_RS12730 57e9e83b2c006e58694efa7791e641e0 466 Hamap MF_01347 ATP synthase subunit beta [atpB]. 13 466 44.625 T 11-11-2016 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 AUP74_RS12730 57e9e83b2c006e58694efa7791e641e0 466 Gene3D G3DSA:1.10.1140.10 357 463 7.8E-35 T 11-11-2016 IPR024034 ATPase, F1 complex beta subunit/V1 complex, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AUP74_RS12730 57e9e83b2c006e58694efa7791e641e0 466 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 18 83 9.1E-8 T 11-11-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AUP74_RS12730 57e9e83b2c006e58694efa7791e641e0 466 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 140 353 1.7E-60 T 11-11-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AUP74_RS12730 57e9e83b2c006e58694efa7791e641e0 466 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 15 464 1.1E-173 T 11-11-2016 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 AUP74_RS12730 57e9e83b2c006e58694efa7791e641e0 466 Gene3D G3DSA:3.40.50.300 87 354 1.8E-90 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS12730 57e9e83b2c006e58694efa7791e641e0 466 SMART SM00382 152 392 0.0023 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS08360 0dd9da7530fad4776dbff3e6f9b083e3 420 PIRSF PIRSF036483 2 418 2.7E-205 T 11-11-2016 IPR011404 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, XF0274 GO:0006096|GO:0047334 KEGG: 00051+2.7.1.90|MetaCyc: PWY-1042 AUP74_RS08360 0dd9da7530fad4776dbff3e6f9b083e3 420 Gene3D G3DSA:3.40.50.450 2 239 6.5E-52 T 11-11-2016 AUP74_RS08360 0dd9da7530fad4776dbff3e6f9b083e3 420 Pfam PF00365 Phosphofructokinase 10 321 7.1E-45 T 11-11-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AUP74_RS08360 0dd9da7530fad4776dbff3e6f9b083e3 420 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 179 195 1.9E-10 T 11-11-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AUP74_RS08360 0dd9da7530fad4776dbff3e6f9b083e3 420 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 237 249 1.9E-10 T 11-11-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AUP74_RS08360 0dd9da7530fad4776dbff3e6f9b083e3 420 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 137 154 1.9E-10 T 11-11-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AUP74_RS08360 0dd9da7530fad4776dbff3e6f9b083e3 420 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 8 27 1.9E-10 T 11-11-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AUP74_RS08360 0dd9da7530fad4776dbff3e6f9b083e3 420 Hamap MF_01978 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 3 399 44.551 T 11-11-2016 IPR011404 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, XF0274 GO:0006096|GO:0047334 KEGG: 00051+2.7.1.90|MetaCyc: PWY-1042 AUP74_RS08360 0dd9da7530fad4776dbff3e6f9b083e3 420 SUPERFAMILY SSF53784 3 413 1.96E-109 T 11-11-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AUP74_RS12050 57f2bd0658efb0ac1b00159d6955dda9 292 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 8 291 8.6E-130 T 11-11-2016 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 AUP74_RS12050 57f2bd0658efb0ac1b00159d6955dda9 292 Gene3D G3DSA:3.20.20.60 8 285 1.2E-99 T 11-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AUP74_RS12050 57f2bd0658efb0ac1b00159d6955dda9 292 Pfam PF13714 Phosphoenolpyruvate phosphomutase 11 255 3.2E-51 T 11-11-2016 AUP74_RS12050 57f2bd0658efb0ac1b00159d6955dda9 292 SUPERFAMILY SSF51621 7 290 1.39E-101 T 11-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AUP74_RS12050 57f2bd0658efb0ac1b00159d6955dda9 292 ProSitePatterns PS00161 Isocitrate lyase signature. 121 126 - T 11-11-2016 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 AUP74_RS12050 57f2bd0658efb0ac1b00159d6955dda9 292 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 5 292 49.609 T 11-11-2016 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 AUP74_RS05310 69d1d45a42cbadf98b17e93ec29f73ea 226 SUPERFAMILY SSF53955 50 218 2.78E-52 T 11-11-2016 IPR023346 Lysozyme-like domain AUP74_RS05310 69d1d45a42cbadf98b17e93ec29f73ea 226 Pfam PF00912 Transglycosylase 50 210 5.2E-45 T 11-11-2016 IPR001264 Glycosyl transferase, family 51 AUP74_RS05310 69d1d45a42cbadf98b17e93ec29f73ea 226 TIGRFAM TIGR02070 mono_pep_trsgly: monofunctional biosynthetic peptidoglycan transglycosylase 22 218 2.0E-74 T 11-11-2016 IPR011812 Monofunctional biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 AUP74_RS05310 69d1d45a42cbadf98b17e93ec29f73ea 226 Hamap MF_00766 Monofunctional biosynthetic peptidoglycan transglycosylase [mtgA]. 4 220 39.181 T 11-11-2016 IPR011812 Monofunctional biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 AUP74_RS05310 69d1d45a42cbadf98b17e93ec29f73ea 226 Gene3D G3DSA:1.10.3810.10 49 217 1.2E-53 T 11-11-2016 AUP74_RS11625 24fa6f589225477a0b0dc23d29136293 256 SUPERFAMILY SSF53335 4 147 2.32E-20 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS11625 24fa6f589225477a0b0dc23d29136293 256 Gene3D G3DSA:3.40.50.150 5 229 2.4E-21 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS11625 24fa6f589225477a0b0dc23d29136293 256 Pfam PF13649 Methyltransferase domain 64 144 2.1E-6 T 11-11-2016 AUP74_RS09870 b7be3f3f2d770e38730bd936c98507f4 502 SUPERFAMILY SSF117457 316 486 1.44E-62 T 11-11-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 AUP74_RS09870 b7be3f3f2d770e38730bd936c98507f4 502 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 325 486 3.9E-47 T 11-11-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 AUP74_RS09870 b7be3f3f2d770e38730bd936c98507f4 502 PIRSF PIRSF001394 1 502 7.5E-216 T 11-11-2016 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 AUP74_RS09870 b7be3f3f2d770e38730bd936c98507f4 502 Pfam PF05681 Fumarate hydratase (Fumerase) 11 284 9.8E-100 T 11-11-2016 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 AUP74_RS09870 b7be3f3f2d770e38730bd936c98507f4 502 Gene3D G3DSA:3.20.130.10 302 487 3.2E-73 T 11-11-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 AUP74_RS09870 b7be3f3f2d770e38730bd936c98507f4 502 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 11 283 6.1E-64 T 11-11-2016 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 AUP74_RS09870 b7be3f3f2d770e38730bd936c98507f4 502 Pfam PF05683 Fumarase C-terminus 288 488 5.1E-81 T 11-11-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 AUP74_RS07475 caba37c8ff731d7b6510bd0c443c8f69 450 Gene3D G3DSA:3.40.192.10 70 190 2.0E-63 T 11-11-2016 AUP74_RS07475 caba37c8ff731d7b6510bd0c443c8f69 450 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 204 448 7.3E-74 T 11-11-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 AUP74_RS07475 caba37c8ff731d7b6510bd0c443c8f69 450 Gene3D G3DSA:1.10.285.10 18 69 6.0E-15 T 11-11-2016 AUP74_RS07475 caba37c8ff731d7b6510bd0c443c8f69 450 SMART SM00839 206 448 7.9E-74 T 11-11-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 AUP74_RS07475 caba37c8ff731d7b6510bd0c443c8f69 450 SUPERFAMILY SSF51735 204 449 7.88E-69 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS07475 caba37c8ff731d7b6510bd0c443c8f69 450 SUPERFAMILY SSF53223 8 198 4.16E-69 T 11-11-2016 AUP74_RS07475 caba37c8ff731d7b6510bd0c443c8f69 450 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 59 187 7.3E-52 T 11-11-2016 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 AUP74_RS07475 caba37c8ff731d7b6510bd0c443c8f69 450 PIRSF PIRSF000185 25 450 3.8E-117 T 11-11-2016 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 AUP74_RS07475 caba37c8ff731d7b6510bd0c443c8f69 450 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 124 137 - T 11-11-2016 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-70614 AUP74_RS07475 caba37c8ff731d7b6510bd0c443c8f69 450 Gene3D G3DSA:3.40.50.720 204 449 3.4E-71 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS07475 caba37c8ff731d7b6510bd0c443c8f69 450 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 195 217 2.8E-31 T 11-11-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 AUP74_RS07475 caba37c8ff731d7b6510bd0c443c8f69 450 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 116 130 2.8E-31 T 11-11-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 AUP74_RS07475 caba37c8ff731d7b6510bd0c443c8f69 450 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 237 257 2.8E-31 T 11-11-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 AUP74_RS07475 caba37c8ff731d7b6510bd0c443c8f69 450 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 374 385 2.8E-31 T 11-11-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 AUP74_RS09420 27b957a7e344da0bcc5add6481aa1141 333 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 48 305 8.3E-80 T 11-11-2016 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 AUP74_RS09420 27b957a7e344da0bcc5add6481aa1141 333 PRINTS PR01755 Bacterial translocase SecF protein signature 173 187 2.6E-29 T 11-11-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial AUP74_RS09420 27b957a7e344da0bcc5add6481aa1141 333 PRINTS PR01755 Bacterial translocase SecF protein signature 47 62 2.6E-29 T 11-11-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial AUP74_RS09420 27b957a7e344da0bcc5add6481aa1141 333 PRINTS PR01755 Bacterial translocase SecF protein signature 221 239 2.6E-29 T 11-11-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial AUP74_RS09420 27b957a7e344da0bcc5add6481aa1141 333 PRINTS PR01755 Bacterial translocase SecF protein signature 253 268 2.6E-29 T 11-11-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial AUP74_RS09420 27b957a7e344da0bcc5add6481aa1141 333 Gene3D G3DSA:1.20.1640.10 115 307 9.2E-30 T 11-11-2016 AUP74_RS09420 27b957a7e344da0bcc5add6481aa1141 333 Pfam PF02355 Protein export membrane protein 133 312 2.9E-66 T 11-11-2016 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial AUP74_RS09420 27b957a7e344da0bcc5add6481aa1141 333 SUPERFAMILY SSF82866 125 310 2.09E-36 T 11-11-2016 AUP74_RS09420 27b957a7e344da0bcc5add6481aa1141 333 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 20 316 28.495 T 11-11-2016 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 AUP74_RS09420 27b957a7e344da0bcc5add6481aa1141 333 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 126 302 1.2E-52 T 11-11-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial AUP74_RS09420 27b957a7e344da0bcc5add6481aa1141 333 Pfam PF07549 SecD/SecF GG Motif 43 68 2.9E-9 T 11-11-2016 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site AUP74_RS11695 49fe6d9fa9b579b94f81cb312263e149 265 Pfam PF08808 RES domain 62 225 3.6E-19 T 11-11-2016 IPR014914 RES domain AUP74_RS11695 49fe6d9fa9b579b94f81cb312263e149 265 SMART SM00953 70 221 8.6E-18 T 11-11-2016 IPR014914 RES domain AUP74_RS07925 7f39c84c1f390fd0cd121aef13dce9df 247 Gene3D G3DSA:1.10.10.200 1 79 9.8E-33 T 11-11-2016 IPR017856 Integrase, N-terminal zinc-binding domain-like AUP74_RS07925 7f39c84c1f390fd0cd121aef13dce9df 247 Gene3D G3DSA:3.30.1270.10 211 246 2.4E-42 T 11-11-2016 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS07925 7f39c84c1f390fd0cd121aef13dce9df 247 Gene3D G3DSA:3.30.1270.10 81 133 2.4E-42 T 11-11-2016 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS07925 7f39c84c1f390fd0cd121aef13dce9df 247 SUPERFAMILY SSF75625 3 245 1.12E-97 T 11-11-2016 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS07925 7f39c84c1f390fd0cd121aef13dce9df 247 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 236 5.2E-102 T 11-11-2016 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS07925 7f39c84c1f390fd0cd121aef13dce9df 247 Gene3D G3DSA:3.30.70.980 134 204 6.5E-29 T 11-11-2016 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS07925 7f39c84c1f390fd0cd121aef13dce9df 247 Pfam PF01709 Transcriptional regulator 5 236 3.5E-97 T 11-11-2016 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS07925 7f39c84c1f390fd0cd121aef13dce9df 247 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 238 36.283 T 11-11-2016 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS14545 0b05af9823e788ed145f75d6d20f71b8 442 Gene3D G3DSA:1.20.1250.20 22 213 8.1E-22 T 11-11-2016 AUP74_RS14545 0b05af9823e788ed145f75d6d20f71b8 442 Gene3D G3DSA:1.20.1250.20 236 429 6.1E-26 T 11-11-2016 AUP74_RS14545 0b05af9823e788ed145f75d6d20f71b8 442 SUPERFAMILY SSF103473 23 429 4.45E-51 T 11-11-2016 IPR020846 Major facilitator superfamily domain AUP74_RS14545 0b05af9823e788ed145f75d6d20f71b8 442 Pfam PF07690 Major Facilitator Superfamily 28 330 2.0E-25 T 11-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AUP74_RS10515 6041df1ea560bfaa1229800bae7c3e80 217 SUPERFAMILY SSF53474 6 215 4.63E-27 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS10515 6041df1ea560bfaa1229800bae7c3e80 217 Gene3D G3DSA:3.40.50.1820 12 212 6.3E-33 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS10230 9fed30c0e0f4c8405443665a23f8d36e 175 Gene3D G3DSA:3.90.950.20 8 172 3.4E-56 T 11-11-2016 IPR008136 CinA, C-terminal AUP74_RS10230 9fed30c0e0f4c8405443665a23f8d36e 175 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 18 166 7.4E-50 T 11-11-2016 IPR008136 CinA, C-terminal AUP74_RS10230 9fed30c0e0f4c8405443665a23f8d36e 175 Pfam PF02464 Competence-damaged protein 13 169 6.7E-58 T 11-11-2016 IPR008136 CinA, C-terminal AUP74_RS10230 9fed30c0e0f4c8405443665a23f8d36e 175 SUPERFAMILY SSF142433 9 171 2.48E-53 T 11-11-2016 IPR008136 CinA, C-terminal AUP74_RS09435 0a1dfbb65d33f21c4b3034c674c4f2de 646 SUPERFAMILY SSF53474 135 316 5.99E-22 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS09435 0a1dfbb65d33f21c4b3034c674c4f2de 646 Pfam PF10503 Esterase PHB depolymerase 58 229 2.3E-20 T 11-11-2016 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 AUP74_RS09435 0a1dfbb65d33f21c4b3034c674c4f2de 646 TIGRFAM TIGR01840 esterase_phb: esterase, PHB depolymerase family 45 248 2.7E-42 T 11-11-2016 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 AUP74_RS09435 0a1dfbb65d33f21c4b3034c674c4f2de 646 Gene3D G3DSA:3.40.50.1820 42 309 1.5E-20 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS09435 0a1dfbb65d33f21c4b3034c674c4f2de 646 SUPERFAMILY SSF53474 37 175 4.87E-13 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS09435 0a1dfbb65d33f21c4b3034c674c4f2de 646 Gene3D G3DSA:2.60.40.1560 422 496 9.7E-6 T 11-11-2016 AUP74_RS12825 2e707d4538e7b1a6b9033bf3d77e3054 760 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 311 323 - T 11-11-2016 IPR018368 ClpA/B, conserved site 1 GO:0005524 AUP74_RS12825 2e707d4538e7b1a6b9033bf3d77e3054 760 SMART SM01086 662 752 6.2E-26 T 11-11-2016 IPR019489 Clp ATPase, C-terminal AUP74_RS12825 2e707d4538e7b1a6b9033bf3d77e3054 760 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 527 545 - T 11-11-2016 IPR028299 ClpA/B, conserved site 2 AUP74_RS12825 2e707d4538e7b1a6b9033bf3d77e3054 760 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 604 618 1.8E-37 T 11-11-2016 IPR001270 ClpA/B family GO:0005524 AUP74_RS12825 2e707d4538e7b1a6b9033bf3d77e3054 760 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 500 518 1.8E-37 T 11-11-2016 IPR001270 ClpA/B family GO:0005524 AUP74_RS12825 2e707d4538e7b1a6b9033bf3d77e3054 760 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 542 560 1.8E-37 T 11-11-2016 IPR001270 ClpA/B family GO:0005524 AUP74_RS12825 2e707d4538e7b1a6b9033bf3d77e3054 760 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 571 589 1.8E-37 T 11-11-2016 IPR001270 ClpA/B family GO:0005524 AUP74_RS12825 2e707d4538e7b1a6b9033bf3d77e3054 760 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 220 332 1.0E-12 T 11-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 AUP74_RS12825 2e707d4538e7b1a6b9033bf3d77e3054 760 Gene3D G3DSA:1.10.1780.10 1 142 2.6E-41 T 11-11-2016 IPR004176 Clp, N-terminal GO:0019538 AUP74_RS12825 2e707d4538e7b1a6b9033bf3d77e3054 760 TIGRFAM TIGR02639 ClpA: ATP-dependent Clp protease ATP-binding subunit ClpA 3 744 0.0 T 11-11-2016 IPR013461 ATP-dependent Clp protease ATP-binding subunit ClpA GO:0004176 AUP74_RS12825 2e707d4538e7b1a6b9033bf3d77e3054 760 SUPERFAMILY SSF52540 176 462 6.05E-69 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS12825 2e707d4538e7b1a6b9033bf3d77e3054 760 SMART SM00382 496 632 1.3E-9 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS12825 2e707d4538e7b1a6b9033bf3d77e3054 760 SMART SM00382 215 361 7.1E-12 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS12825 2e707d4538e7b1a6b9033bf3d77e3054 760 SUPERFAMILY SSF52540 446 738 2.35E-76 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS12825 2e707d4538e7b1a6b9033bf3d77e3054 760 Gene3D G3DSA:3.40.50.300 179 359 6.7E-43 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS12825 2e707d4538e7b1a6b9033bf3d77e3054 760 Gene3D G3DSA:3.40.50.300 452 673 3.1E-56 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS12825 2e707d4538e7b1a6b9033bf3d77e3054 760 SUPERFAMILY SSF81923 1 142 1.83E-59 T 11-11-2016 IPR004176 Clp, N-terminal GO:0019538 AUP74_RS12825 2e707d4538e7b1a6b9033bf3d77e3054 760 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 662 743 3.8E-21 T 11-11-2016 IPR019489 Clp ATPase, C-terminal AUP74_RS12825 2e707d4538e7b1a6b9033bf3d77e3054 760 Gene3D G3DSA:1.10.8.60 361 445 8.3E-29 T 11-11-2016 AUP74_RS12825 2e707d4538e7b1a6b9033bf3d77e3054 760 Pfam PF07724 AAA domain (Cdc48 subfamily) 495 656 5.9E-50 T 11-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 AUP74_RS12825 2e707d4538e7b1a6b9033bf3d77e3054 760 Gene3D G3DSA:1.10.8.60 674 754 3.6E-26 T 11-11-2016 AUP74_RS12825 2e707d4538e7b1a6b9033bf3d77e3054 760 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 15 62 1.2E-13 T 11-11-2016 IPR004176 Clp, N-terminal GO:0019538 AUP74_RS07060 45e069461c23234b59d1aee34cd8cd98 229 SMART SM00862 154 227 8.5E-15 T 11-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AUP74_RS07060 45e069461c23234b59d1aee34cd8cd98 229 Pfam PF00072 Response regulator receiver domain 5 117 2.4E-21 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS07060 45e069461c23234b59d1aee34cd8cd98 229 TIGRFAM TIGR03787 marine_sort_RR: proteobacterial dedicated sortase system response regulator 5 228 5.8E-112 T 11-11-2016 IPR022305 Sortase system response regulator AUP74_RS07060 45e069461c23234b59d1aee34cd8cd98 229 SMART SM00448 3 116 1.1E-27 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS07060 45e069461c23234b59d1aee34cd8cd98 229 SUPERFAMILY SSF46894 128 227 1.67E-20 T 11-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AUP74_RS07060 45e069461c23234b59d1aee34cd8cd98 229 Gene3D G3DSA:3.40.50.2300 2 130 1.4E-32 T 11-11-2016 AUP74_RS07060 45e069461c23234b59d1aee34cd8cd98 229 Gene3D G3DSA:1.10.10.10 131 228 1.6E-21 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS07060 45e069461c23234b59d1aee34cd8cd98 229 SUPERFAMILY SSF52172 2 128 1.99E-31 T 11-11-2016 IPR011006 CheY-like superfamily AUP74_RS07060 45e069461c23234b59d1aee34cd8cd98 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 226 2.9E-14 T 11-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AUP74_RS14075 607524403ee672747ca9c01df266f8f7 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 68 6.6E-17 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS14075 607524403ee672747ca9c01df266f8f7 305 Gene3D G3DSA:1.10.10.10 10 87 3.0E-22 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS14075 607524403ee672747ca9c01df266f8f7 305 Pfam PF03466 LysR substrate binding domain 94 295 7.2E-23 T 11-11-2016 IPR005119 LysR, substrate-binding AUP74_RS14075 607524403ee672747ca9c01df266f8f7 305 SUPERFAMILY SSF46785 10 92 1.59E-17 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS14075 607524403ee672747ca9c01df266f8f7 305 Gene3D G3DSA:3.40.190.10 88 185 1.8E-9 T 11-11-2016 AUP74_RS14075 607524403ee672747ca9c01df266f8f7 305 Gene3D G3DSA:3.40.190.10 186 257 6.2E-6 T 11-11-2016 AUP74_RS14075 607524403ee672747ca9c01df266f8f7 305 SUPERFAMILY SSF53850 98 299 1.16E-28 T 11-11-2016 AUP74_RS01520 4b790a09b7d604a23b36c861c9e777ec 188 SUPERFAMILY SSF142695 2 156 3.14E-61 T 11-11-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 AUP74_RS01520 4b790a09b7d604a23b36c861c9e777ec 188 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 1 180 39.524 T 11-11-2016 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 AUP74_RS01520 4b790a09b7d604a23b36c861c9e777ec 188 Pfam PF00925 GTP cyclohydrolase II 2 154 3.0E-66 T 11-11-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 AUP74_RS01520 4b790a09b7d604a23b36c861c9e777ec 188 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 2 177 3.2E-76 T 11-11-2016 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 AUP74_RS10270 b599e78f20c5c0e5f5e2f4989e7338c7 870 PRINTS PR00980 Alanyl-tRNA synthetase signature 270 286 5.8E-33 T 11-11-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AUP74_RS10270 b599e78f20c5c0e5f5e2f4989e7338c7 870 PRINTS PR00980 Alanyl-tRNA synthetase signature 294 307 5.8E-33 T 11-11-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AUP74_RS10270 b599e78f20c5c0e5f5e2f4989e7338c7 870 PRINTS PR00980 Alanyl-tRNA synthetase signature 74 85 5.8E-33 T 11-11-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AUP74_RS10270 b599e78f20c5c0e5f5e2f4989e7338c7 870 PRINTS PR00980 Alanyl-tRNA synthetase signature 197 208 5.8E-33 T 11-11-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AUP74_RS10270 b599e78f20c5c0e5f5e2f4989e7338c7 870 PRINTS PR00980 Alanyl-tRNA synthetase signature 224 237 5.8E-33 T 11-11-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AUP74_RS10270 b599e78f20c5c0e5f5e2f4989e7338c7 870 SUPERFAMILY SSF101353 244 451 1.23E-62 T 11-11-2016 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 AUP74_RS10270 b599e78f20c5c0e5f5e2f4989e7338c7 870 SMART SM00863 641 690 8.0E-20 T 11-11-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 AUP74_RS10270 b599e78f20c5c0e5f5e2f4989e7338c7 870 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 641 690 2.4E-16 T 11-11-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 AUP74_RS10270 b599e78f20c5c0e5f5e2f4989e7338c7 870 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 848 0.0 T 11-11-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AUP74_RS10270 b599e78f20c5c0e5f5e2f4989e7338c7 870 Pfam PF02272 DHHA1 domain 794 861 1.9E-14 T 11-11-2016 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 AUP74_RS10270 b599e78f20c5c0e5f5e2f4989e7338c7 870 SUPERFAMILY SSF50447 442 540 5.89E-22 T 11-11-2016 IPR009000 Translation protein, beta-barrel domain AUP74_RS10270 b599e78f20c5c0e5f5e2f4989e7338c7 870 Pfam PF01411 tRNA synthetases class II (A) 5 542 1.5E-223 T 11-11-2016 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 AUP74_RS10270 b599e78f20c5c0e5f5e2f4989e7338c7 870 SUPERFAMILY SSF55681 2 243 3.98E-106 T 11-11-2016 AUP74_RS10270 b599e78f20c5c0e5f5e2f4989e7338c7 870 SUPERFAMILY SSF55186 541 701 1.7E-48 T 11-11-2016 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 AUP74_RS10270 b599e78f20c5c0e5f5e2f4989e7338c7 870 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 869 197.693 T 11-11-2016 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 AUP74_RS10270 b599e78f20c5c0e5f5e2f4989e7338c7 870 Gene3D G3DSA:3.30.930.10 1 240 2.5E-114 T 11-11-2016 AUP74_RS15865 bd4678a8693430f21a8c008ed9ba4232 176 ProSitePatterns PS00087 Copper/Zinc superoxide dismutase signature 1. 69 79 - T 11-11-2016 IPR018152 Superoxide dismutase, copper/zinc, binding site GO:0004784|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 AUP74_RS15865 bd4678a8693430f21a8c008ed9ba4232 176 ProSitePatterns PS00332 Copper/Zinc superoxide dismutase signature 2. 164 175 - T 11-11-2016 IPR018152 Superoxide dismutase, copper/zinc, binding site GO:0004784|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 AUP74_RS15865 bd4678a8693430f21a8c008ed9ba4232 176 SUPERFAMILY SSF49329 24 175 7.46E-48 T 11-11-2016 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 AUP74_RS15865 bd4678a8693430f21a8c008ed9ba4232 176 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 37 175 5.9E-31 T 11-11-2016 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 AUP74_RS15865 bd4678a8693430f21a8c008ed9ba4232 176 Gene3D G3DSA:2.60.40.200 26 175 2.7E-43 T 11-11-2016 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 AUP74_RS12400 4a9f2fba7a05d86fd428a577ff6eac75 271 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 2 269 2.0E-88 T 11-11-2016 AUP74_RS12400 4a9f2fba7a05d86fd428a577ff6eac75 271 SUPERFAMILY SSF56219 2 270 1.22E-81 T 11-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase AUP74_RS12400 4a9f2fba7a05d86fd428a577ff6eac75 271 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 270 1.6E-78 T 11-11-2016 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 AUP74_RS12400 4a9f2fba7a05d86fd428a577ff6eac75 271 Gene3D G3DSA:3.60.10.10 1 270 1.7E-78 T 11-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase AUP74_RS12400 4a9f2fba7a05d86fd428a577ff6eac75 271 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 262 6.6E-27 T 11-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase AUP74_RS12400 4a9f2fba7a05d86fd428a577ff6eac75 271 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 27 36 - T 11-11-2016 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 AUP74_RS07725 7a4da2b97a8297edeec928a9692ca194 191 PIRSF PIRSF006102 1 191 1.6E-56 T 11-11-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 AUP74_RS07725 7a4da2b97a8297edeec928a9692ca194 191 Pfam PF02508 Rnf-Nqr subunit, membrane protein 7 190 1.1E-58 T 11-11-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 AUP74_RS07725 7a4da2b97a8297edeec928a9692ca194 191 Hamap MF_00459 Electron transport complex subunit RsxA [rsxA]. 2 191 24.683 T 11-11-2016 IPR011293 Electron transport complex, subunit RnfA/RsxA GO:0022900 AUP74_RS07725 7a4da2b97a8297edeec928a9692ca194 191 TIGRFAM TIGR01943 rnfA: electron transport complex, RnfABCDGE type, A subunit 3 191 1.2E-81 T 11-11-2016 IPR011293 Electron transport complex, subunit RnfA/RsxA GO:0022900 AUP74_RS15230 5207ddde27072adbe82bfa2d89ac4bfc 169 SUPERFAMILY SSF54975 4 138 1.31E-33 T 11-11-2016 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 AUP74_RS15230 5207ddde27072adbe82bfa2d89ac4bfc 169 Pfam PF04940 Sensors of blue-light using FAD 4 101 8.4E-27 T 11-11-2016 IPR007024 BLUF domain GO:0009882|GO:0071949 AUP74_RS15230 5207ddde27072adbe82bfa2d89ac4bfc 169 SMART SM01034 4 102 7.6E-39 T 11-11-2016 IPR007024 BLUF domain GO:0009882|GO:0071949 AUP74_RS01850 e4178899ae5818698952340c9365288f 204 ProSitePatterns PS00211 ABC transporters family signature. 118 132 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AUP74_RS01850 e4178899ae5818698952340c9365288f 204 SUPERFAMILY SSF52540 16 199 2.92E-42 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS01850 e4178899ae5818698952340c9365288f 204 Gene3D G3DSA:3.40.50.300 16 199 1.3E-41 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS01850 e4178899ae5818698952340c9365288f 204 Pfam PF00005 ABC transporter 16 146 1.5E-22 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AUP74_RS01850 e4178899ae5818698952340c9365288f 204 SMART SM00382 25 195 5.3E-11 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS02370 1bdfc9a1fa3319a4a7bfac37c97b11c3 401 SUPERFAMILY SSF141523 274 323 5.62E-20 T 11-11-2016 AUP74_RS02370 1bdfc9a1fa3319a4a7bfac37c97b11c3 401 SUPERFAMILY SSF141523 166 221 5.62E-20 T 11-11-2016 AUP74_RS02370 1bdfc9a1fa3319a4a7bfac37c97b11c3 401 SUPERFAMILY SSF47090 60 149 3.45E-15 T 11-11-2016 IPR002477 Peptidoglycan binding-like AUP74_RS02370 1bdfc9a1fa3319a4a7bfac37c97b11c3 401 Gene3D G3DSA:2.40.440.10 276 324 2.2E-13 T 11-11-2016 AUP74_RS02370 1bdfc9a1fa3319a4a7bfac37c97b11c3 401 Gene3D G3DSA:2.40.440.10 163 212 2.2E-13 T 11-11-2016 AUP74_RS02370 1bdfc9a1fa3319a4a7bfac37c97b11c3 401 Gene3D G3DSA:1.10.101.10 61 150 2.9E-16 T 11-11-2016 IPR002477 Peptidoglycan binding-like AUP74_RS02370 1bdfc9a1fa3319a4a7bfac37c97b11c3 401 Pfam PF03734 L,D-transpeptidase catalytic domain 167 331 5.2E-32 T 11-11-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 AUP74_RS02370 1bdfc9a1fa3319a4a7bfac37c97b11c3 401 Pfam PF01471 Putative peptidoglycan binding domain 75 140 3.4E-11 T 11-11-2016 IPR002477 Peptidoglycan binding-like AUP74_RS03915 6b90914512d2d2b94e50c9b73a6bbeb2 269 Pfam PF13505 Outer membrane protein beta-barrel domain 13 181 4.1E-15 T 11-11-2016 IPR027385 Outer membrane protein beta-barrel AUP74_RS03915 6b90914512d2d2b94e50c9b73a6bbeb2 269 Gene3D G3DSA:4.10.1080.10 209 260 1.7E-9 T 11-11-2016 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 AUP74_RS03915 6b90914512d2d2b94e50c9b73a6bbeb2 269 SUPERFAMILY SSF103647 205 267 1.16E-11 T 11-11-2016 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 AUP74_RS03915 6b90914512d2d2b94e50c9b73a6bbeb2 269 Gene3D G3DSA:2.40.160.20 14 201 1.4E-14 T 11-11-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AUP74_RS03915 6b90914512d2d2b94e50c9b73a6bbeb2 269 SUPERFAMILY SSF56925 34 183 2.3E-12 T 11-11-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AUP74_RS03915 6b90914512d2d2b94e50c9b73a6bbeb2 269 Pfam PF02412 Thrombospondin type 3 repeat 235 256 4.4E-4 T 11-11-2016 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 AUP74_RS00365 55a7b6e01907b7df2ab671692305582a 340 Pfam PF02562 PhoH-like protein 120 323 1.1E-93 T 11-11-2016 IPR003714 PhoH-like protein GO:0005524 AUP74_RS00365 55a7b6e01907b7df2ab671692305582a 340 Gene3D G3DSA:3.40.50.300 119 322 1.3E-87 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS00365 55a7b6e01907b7df2ab671692305582a 340 SUPERFAMILY SSF52540 90 298 4.2E-39 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS09090 a58edbb220e0bc793279fea25200cfe4 267 Gene3D G3DSA:3.30.540.10 2 149 2.5E-47 T 11-11-2016 AUP74_RS09090 a58edbb220e0bc793279fea25200cfe4 267 Pfam PF00459 Inositol monophosphatase family 1 255 8.5E-62 T 11-11-2016 IPR000760 Inositol monophosphatase GO:0046854 AUP74_RS09090 a58edbb220e0bc793279fea25200cfe4 267 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 81 94 - T 11-11-2016 IPR020583 Inositol monophosphatase, metal-binding site AUP74_RS09090 a58edbb220e0bc793279fea25200cfe4 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 81 97 8.9E-60 T 11-11-2016 IPR000760 Inositol monophosphatase GO:0046854 AUP74_RS09090 a58edbb220e0bc793279fea25200cfe4 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 60 76 8.9E-60 T 11-11-2016 IPR000760 Inositol monophosphatase GO:0046854 AUP74_RS09090 a58edbb220e0bc793279fea25200cfe4 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 38 58 8.9E-60 T 11-11-2016 IPR000760 Inositol monophosphatase GO:0046854 AUP74_RS09090 a58edbb220e0bc793279fea25200cfe4 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 130 153 8.9E-60 T 11-11-2016 IPR000760 Inositol monophosphatase GO:0046854 AUP74_RS09090 a58edbb220e0bc793279fea25200cfe4 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 179 200 8.9E-60 T 11-11-2016 IPR000760 Inositol monophosphatase GO:0046854 AUP74_RS09090 a58edbb220e0bc793279fea25200cfe4 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 210 234 8.9E-60 T 11-11-2016 IPR000760 Inositol monophosphatase GO:0046854 AUP74_RS09090 a58edbb220e0bc793279fea25200cfe4 267 PRINTS PR01959 SuhB family inositol monophosphatase signature 200 212 2.7E-18 T 11-11-2016 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 AUP74_RS09090 a58edbb220e0bc793279fea25200cfe4 267 PRINTS PR01959 SuhB family inositol monophosphatase signature 17 39 2.7E-18 T 11-11-2016 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 AUP74_RS09090 a58edbb220e0bc793279fea25200cfe4 267 PRINTS PR01959 SuhB family inositol monophosphatase signature 104 123 2.7E-18 T 11-11-2016 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 AUP74_RS09090 a58edbb220e0bc793279fea25200cfe4 267 PRINTS PR01959 SuhB family inositol monophosphatase signature 158 184 2.7E-18 T 11-11-2016 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 AUP74_RS09090 a58edbb220e0bc793279fea25200cfe4 267 SUPERFAMILY SSF56655 1 261 1.31E-80 T 11-11-2016 AUP74_RS09090 a58edbb220e0bc793279fea25200cfe4 267 Gene3D G3DSA:3.40.190.80 150 261 3.2E-35 T 11-11-2016 AUP74_RS09090 a58edbb220e0bc793279fea25200cfe4 267 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 213 227 - T 11-11-2016 IPR020550 Inositol monophosphatase, conserved site GO:0046854 AUP74_RS16570 bc7d05ad25e51fcdd6913ac095a42b2e 590 Gene3D G3DSA:4.10.80.40 557 590 1.1E-19 T 11-11-2016 AUP74_RS16570 bc7d05ad25e51fcdd6913ac095a42b2e 590 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 8 590 1.8E-297 T 11-11-2016 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 AUP74_RS16570 bc7d05ad25e51fcdd6913ac095a42b2e 590 PIRSF PIRSF000171 1 579 4.6E-44 T 11-11-2016 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit Reactome: R-HSA-611105|Reactome: R-HSA-71403 AUP74_RS16570 bc7d05ad25e51fcdd6913ac095a42b2e 590 SUPERFAMILY SSF46977 453 590 1.07E-47 T 11-11-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AUP74_RS16570 bc7d05ad25e51fcdd6913ac095a42b2e 590 SUPERFAMILY SSF51905 361 425 2.27E-73 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS16570 bc7d05ad25e51fcdd6913ac095a42b2e 590 SUPERFAMILY SSF51905 5 262 2.27E-73 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS16570 bc7d05ad25e51fcdd6913ac095a42b2e 590 Gene3D G3DSA:3.50.50.60 353 424 4.7E-118 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS16570 bc7d05ad25e51fcdd6913ac095a42b2e 590 Gene3D G3DSA:3.50.50.60 3 245 4.7E-118 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS16570 bc7d05ad25e51fcdd6913ac095a42b2e 590 Pfam PF00890 FAD binding domain 10 407 1.4E-120 T 11-11-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 AUP74_RS16570 bc7d05ad25e51fcdd6913ac095a42b2e 590 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 10 590 2.9E-252 T 11-11-2016 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 AUP74_RS16570 bc7d05ad25e51fcdd6913ac095a42b2e 590 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 44 53 - T 11-11-2016 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AUP74_RS16570 bc7d05ad25e51fcdd6913ac095a42b2e 590 SUPERFAMILY SSF56425 239 358 1.03E-41 T 11-11-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 AUP74_RS16570 bc7d05ad25e51fcdd6913ac095a42b2e 590 Pfam PF02910 Fumarate reductase flavoprotein C-term 462 590 2.7E-40 T 11-11-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AUP74_RS16570 bc7d05ad25e51fcdd6913ac095a42b2e 590 Gene3D G3DSA:1.20.58.100 449 556 4.0E-38 T 11-11-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AUP74_RS16570 bc7d05ad25e51fcdd6913ac095a42b2e 590 Gene3D G3DSA:3.90.700.10 246 352 2.0E-41 T 11-11-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 AUP74_RS09060 c8077c235f829766dd79826e6c2a5861 107 Gene3D G3DSA:1.20.1440.40 5 104 1.5E-36 T 11-11-2016 IPR023376 YqcC-like domain AUP74_RS09060 c8077c235f829766dd79826e6c2a5861 107 Pfam PF04287 tRNA pseudouridine synthase C 8 103 4.2E-35 T 11-11-2016 IPR023376 YqcC-like domain AUP74_RS09060 c8077c235f829766dd79826e6c2a5861 107 SUPERFAMILY SSF158452 4 106 2.22E-38 T 11-11-2016 IPR023376 YqcC-like domain AUP74_RS09060 c8077c235f829766dd79826e6c2a5861 107 PIRSF PIRSF006257 2 107 1.9E-36 T 11-11-2016 IPR007384 Protein of unknown function UCP006257 AUP74_RS09530 da348bbca9a665c8962e91310066f7ce 290 Pfam PF03186 CobD/Cbib protein 22 217 1.7E-9 T 11-11-2016 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 AUP74_RS09240 b049c3d2cfe49fc7a543b7ccc34163b2 528 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 4 506 3.9E-164 T 11-11-2016 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09240 b049c3d2cfe49fc7a543b7ccc34163b2 528 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 384 410 2.5E-36 T 11-11-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09240 b049c3d2cfe49fc7a543b7ccc34163b2 528 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 139 158 2.5E-36 T 11-11-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09240 b049c3d2cfe49fc7a543b7ccc34163b2 528 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 169 193 2.5E-36 T 11-11-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09240 b049c3d2cfe49fc7a543b7ccc34163b2 528 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 244 268 2.5E-36 T 11-11-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09240 b049c3d2cfe49fc7a543b7ccc34163b2 528 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 332 351 2.5E-36 T 11-11-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09240 b049c3d2cfe49fc7a543b7ccc34163b2 528 Pfam PF00361 Proton-conducting membrane transporter 133 421 4.6E-72 T 11-11-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS11640 57315019f17c5c4df6ed02c7d6bb2036 230 Gene3D G3DSA:3.10.290.10 1 63 1.0E-19 T 11-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 AUP74_RS11640 57315019f17c5c4df6ed02c7d6bb2036 230 Pfam PF01479 S4 domain 1 46 3.6E-9 T 11-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 AUP74_RS11640 57315019f17c5c4df6ed02c7d6bb2036 230 SUPERFAMILY SSF55174 1 86 8.39E-14 T 11-11-2016 AUP74_RS11640 57315019f17c5c4df6ed02c7d6bb2036 230 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 98 112 - T 11-11-2016 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 AUP74_RS11640 57315019f17c5c4df6ed02c7d6bb2036 230 Pfam PF00849 RNA pseudouridylate synthase 61 191 3.1E-17 T 11-11-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS11640 57315019f17c5c4df6ed02c7d6bb2036 230 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 65 222 3.3E-49 T 11-11-2016 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 AUP74_RS11640 57315019f17c5c4df6ed02c7d6bb2036 230 SUPERFAMILY SSF55120 60 226 1.1E-46 T 11-11-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS11640 57315019f17c5c4df6ed02c7d6bb2036 230 SMART SM00363 1 59 3.9E-11 T 11-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 AUP74_RS14625 5f5bbea24235b4dae42ce33ed96235a8 464 Pfam PF03972 MmgE/PrpD family 6 423 3.8E-94 T 11-11-2016 IPR005656 MmgE/PrpD GO:0016829 AUP74_RS14625 5f5bbea24235b4dae42ce33ed96235a8 464 SUPERFAMILY SSF103378 5 452 1.7E-88 T 11-11-2016 IPR005656 MmgE/PrpD GO:0016829 AUP74_RS14625 5f5bbea24235b4dae42ce33ed96235a8 464 Gene3D G3DSA:3.30.1330.120 266 391 3.8E-18 T 11-11-2016 AUP74_RS13620 824af38dbab6d3c78bb2a1c845498dc3 168 Pfam PF12973 ChrR Cupin-like domain 27 105 2.2E-7 T 11-11-2016 IPR025979 ChrR-like cupin domain AUP74_RS13620 824af38dbab6d3c78bb2a1c845498dc3 168 SUPERFAMILY SSF51182 15 142 1.38E-22 T 11-11-2016 IPR011051 RmlC-like cupin domain AUP74_RS13620 824af38dbab6d3c78bb2a1c845498dc3 168 Gene3D G3DSA:2.60.120.10 14 157 7.9E-46 T 11-11-2016 IPR014710 RmlC-like jelly roll fold AUP74_RS06110 8282d0dd25c2fbaae4427342ce2e4c27 535 Gene3D G3DSA:3.90.226.10 28 269 1.1E-86 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS06110 8282d0dd25c2fbaae4427342ce2e4c27 535 Gene3D G3DSA:3.90.226.10 278 530 1.3E-97 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS06110 8282d0dd25c2fbaae4427342ce2e4c27 535 SUPERFAMILY SSF52096 276 535 8.25E-91 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS06110 8282d0dd25c2fbaae4427342ce2e4c27 535 Pfam PF01039 Carboxyl transferase domain 48 525 6.4E-160 T 11-11-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AUP74_RS06110 8282d0dd25c2fbaae4427342ce2e4c27 535 SUPERFAMILY SSF52096 24 267 8.82E-75 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS15780 1a21a94862ad9e4cca13f53257da056d 290 SUPERFAMILY SSF51735 2 167 5.39E-23 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS15780 1a21a94862ad9e4cca13f53257da056d 290 Gene3D G3DSA:1.10.1040.20 167 268 3.0E-26 T 11-11-2016 IPR018931 Domain of unknown function DUF2520 AUP74_RS15780 1a21a94862ad9e4cca13f53257da056d 290 Pfam PF10728 Domain of unknown function (DUF2520) 136 262 2.3E-33 T 11-11-2016 IPR018931 Domain of unknown function DUF2520 AUP74_RS15780 1a21a94862ad9e4cca13f53257da056d 290 SUPERFAMILY SSF48179 168 270 4.42E-22 T 11-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AUP74_RS15780 1a21a94862ad9e4cca13f53257da056d 290 Pfam PF10727 Rossmann-like domain 3 107 8.5E-5 T 11-11-2016 IPR019665 Putative oxidoreductase/dehydrogenase, Rossmann-like domain AUP74_RS15780 1a21a94862ad9e4cca13f53257da056d 290 Gene3D G3DSA:3.40.50.720 2 165 1.1E-35 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS15520 53a2aa9aaf7b4adb2f0dda3beedfda21 302 SUPERFAMILY SSF103481 41 150 8.89E-7 T 11-11-2016 AUP74_RS15520 53a2aa9aaf7b4adb2f0dda3beedfda21 302 SUPERFAMILY SSF103481 217 295 1.15E-10 T 11-11-2016 AUP74_RS15520 53a2aa9aaf7b4adb2f0dda3beedfda21 302 Pfam PF00892 EamA-like transporter family 159 292 2.7E-20 T 11-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 AUP74_RS15520 53a2aa9aaf7b4adb2f0dda3beedfda21 302 Pfam PF00892 EamA-like transporter family 8 149 8.6E-19 T 11-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 AUP74_RS12170 b571b3b616c9db60c8681874bff32991 494 Pfam PF03972 MmgE/PrpD family 18 478 6.9E-146 T 11-11-2016 IPR005656 MmgE/PrpD GO:0016829 AUP74_RS12170 b571b3b616c9db60c8681874bff32991 494 SUPERFAMILY SSF103378 13 493 1.44E-146 T 11-11-2016 IPR005656 MmgE/PrpD GO:0016829 AUP74_RS12170 b571b3b616c9db60c8681874bff32991 494 Gene3D G3DSA:3.30.1330.120 300 437 6.9E-47 T 11-11-2016 AUP74_RS12170 b571b3b616c9db60c8681874bff32991 494 TIGRFAM TIGR02330 prpD: 2-methylcitrate dehydratase 14 494 3.3E-244 T 11-11-2016 IPR012705 2-methylcitrate dehydratase PrpD GO:0019629|GO:0047547|GO:0051537 KEGG: 00640+4.2.1.79 AUP74_RS10460 9ea293c5ff72656e5d0582646945411e 601 Pfam PF09382 RQC domain 399 508 6.6E-43 T 11-11-2016 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 AUP74_RS10460 9ea293c5ff72656e5d0582646945411e 601 SMART SM00341 525 600 1.9E-14 T 11-11-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 AUP74_RS10460 9ea293c5ff72656e5d0582646945411e 601 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 5 597 1.6E-244 T 11-11-2016 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 AUP74_RS10460 9ea293c5ff72656e5d0582646945411e 601 Pfam PF00271 Helicase conserved C-terminal domain 217 323 7.0E-15 T 11-11-2016 IPR001650 Helicase, C-terminal AUP74_RS10460 9ea293c5ff72656e5d0582646945411e 601 Pfam PF16124 RecQ zinc-binding 335 397 1.2E-17 T 11-11-2016 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain AUP74_RS10460 9ea293c5ff72656e5d0582646945411e 601 Gene3D G3DSA:3.40.50.300 197 336 2.1E-47 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS10460 9ea293c5ff72656e5d0582646945411e 601 SUPERFAMILY SSF47819 527 598 9.38E-24 T 11-11-2016 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 AUP74_RS10460 9ea293c5ff72656e5d0582646945411e 601 SMART SM00490 242 323 2.6E-24 T 11-11-2016 IPR001650 Helicase, C-terminal AUP74_RS10460 9ea293c5ff72656e5d0582646945411e 601 Gene3D G3DSA:1.10.10.10 337 509 9.5E-63 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS10460 9ea293c5ff72656e5d0582646945411e 601 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 6 455 2.8E-158 T 11-11-2016 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 AUP74_RS10460 9ea293c5ff72656e5d0582646945411e 601 SUPERFAMILY SSF52540 12 156 6.17E-43 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS10460 9ea293c5ff72656e5d0582646945411e 601 SUPERFAMILY SSF52540 297 340 6.17E-43 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS10460 9ea293c5ff72656e5d0582646945411e 601 Pfam PF00570 HRDC domain 530 595 1.2E-22 T 11-11-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 AUP74_RS10460 9ea293c5ff72656e5d0582646945411e 601 Pfam PF00270 DEAD/DEAH box helicase 19 178 6.0E-18 T 11-11-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AUP74_RS10460 9ea293c5ff72656e5d0582646945411e 601 Gene3D G3DSA:3.40.50.300 6 195 3.6E-54 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS10460 9ea293c5ff72656e5d0582646945411e 601 SMART SM00956 404 507 1.1E-55 T 11-11-2016 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 AUP74_RS10460 9ea293c5ff72656e5d0582646945411e 601 Gene3D G3DSA:1.10.150.80 530 598 1.7E-21 T 11-11-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 AUP74_RS10460 9ea293c5ff72656e5d0582646945411e 601 SUPERFAMILY SSF52540 199 451 2.34E-63 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS10460 9ea293c5ff72656e5d0582646945411e 601 SMART SM00487 13 209 4.9E-30 T 11-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain AUP74_RS10160 60fd1130eaa00b5f6c3fc05f452a39ab 223 SUPERFAMILY SSF53254 4 221 6.55E-40 T 11-11-2016 IPR029033 Histidine phosphatase superfamily AUP74_RS10160 60fd1130eaa00b5f6c3fc05f452a39ab 223 SMART SM00855 3 166 7.1E-10 T 11-11-2016 IPR013078 Histidine phosphatase superfamily, clade-1 AUP74_RS10160 60fd1130eaa00b5f6c3fc05f452a39ab 223 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 7 206 6.0E-25 T 11-11-2016 IPR013078 Histidine phosphatase superfamily, clade-1 AUP74_RS10160 60fd1130eaa00b5f6c3fc05f452a39ab 223 Gene3D G3DSA:3.40.50.1240 3 214 6.3E-35 T 11-11-2016 IPR029033 Histidine phosphatase superfamily AUP74_RS14825 841d5f3081c591e55e411fc4b0751d55 446 SUPERFAMILY SSF51338 11 69 1.36E-26 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS14825 841d5f3081c591e55e411fc4b0751d55 446 SUPERFAMILY SSF51338 367 441 1.36E-26 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS14825 841d5f3081c591e55e411fc4b0751d55 446 Gene3D G3DSA:3.20.20.140 72 375 1.3E-101 T 11-11-2016 AUP74_RS14825 841d5f3081c591e55e411fc4b0751d55 446 SUPERFAMILY SSF51556 69 368 2.72E-98 T 11-11-2016 IPR032466 Metal-dependent hydrolase AUP74_RS14825 841d5f3081c591e55e411fc4b0751d55 446 Hamap MF_01281 5'-deoxyadenosine deaminase [dadD]. 11 442 40.852 T 11-11-2016 IPR023512 Deaminase MtaD/DadD GO:0019239 AUP74_RS14825 841d5f3081c591e55e411fc4b0751d55 446 Pfam PF01979 Amidohydrolase family 67 415 1.3E-73 T 11-11-2016 IPR006680 Amidohydrolase-related GO:0016787 AUP74_RS14825 841d5f3081c591e55e411fc4b0751d55 446 Gene3D G3DSA:2.30.40.10 376 416 1.5E-14 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS14825 841d5f3081c591e55e411fc4b0751d55 446 Gene3D G3DSA:2.30.40.10 11 71 1.5E-14 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS02030 e27db123f05c2d02896ecd29d60d76f5 225 SUPERFAMILY SSF48613 1 214 7.09E-66 T 11-11-2016 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 AUP74_RS02030 e27db123f05c2d02896ecd29d60d76f5 225 Gene3D G3DSA:1.20.910.10 1 211 6.2E-21 T 11-11-2016 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 AUP74_RS02030 e27db123f05c2d02896ecd29d60d76f5 225 SMART SM01236 73 170 2.1E-4 T 11-11-2016 AUP74_RS02030 e27db123f05c2d02896ecd29d60d76f5 225 Pfam PF14518 Iron-containing redox enzyme 39 206 3.2E-27 T 11-11-2016 IPR028201 PqqC-like protein AUP74_RS09490 55e6ac9130eea459b4a0d2c06b7e9e0d 81 TIGRFAM TIGR00847 ccoS: cytochrome oxidase maturation protein, cbb3-type 2 47 2.5E-14 T 11-11-2016 IPR004714 Cytochrome oxidase maturation protein cbb3-type AUP74_RS09490 55e6ac9130eea459b4a0d2c06b7e9e0d 81 Pfam PF03597 Cytochrome oxidase maturation protein cbb3-type 2 45 1.7E-21 T 11-11-2016 IPR004714 Cytochrome oxidase maturation protein cbb3-type AUP74_RS15980 af667b1282bca1af721b9f26402e26f7 406 Pfam PF03631 Virulence factor BrkB 21 266 3.7E-54 T 11-11-2016 IPR017039 Virulence factor BrkB AUP74_RS15980 af667b1282bca1af721b9f26402e26f7 406 Hamap MF_00672 UPF0761 membrane protein YihY [yihY]. 1 291 21.649 T 11-11-2016 IPR023679 Uncharacterised protein family UPF0761, bacterial AUP74_RS15980 af667b1282bca1af721b9f26402e26f7 406 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 11 267 2.2E-63 T 11-11-2016 IPR017039 Virulence factor BrkB AUP74_RS06695 35f44ddfa3cd0a915f6f83a45dc3673d 250 SUPERFAMILY SSF52540 2 223 7.94E-59 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS06695 35f44ddfa3cd0a915f6f83a45dc3673d 250 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AUP74_RS06695 35f44ddfa3cd0a915f6f83a45dc3673d 250 Pfam PF00005 ABC transporter 17 160 1.3E-26 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AUP74_RS06695 35f44ddfa3cd0a915f6f83a45dc3673d 250 SMART SM00382 26 209 8.1E-12 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS06695 35f44ddfa3cd0a915f6f83a45dc3673d 250 Gene3D G3DSA:3.40.50.300 1 224 5.2E-65 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS01075 c356daea9bcf46cc6d73c3a408bdcc48 226 Gene3D G3DSA:3.40.50.300 2 221 2.3E-72 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS01075 c356daea9bcf46cc6d73c3a408bdcc48 226 Pfam PF00005 ABC transporter 21 169 4.3E-33 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AUP74_RS01075 c356daea9bcf46cc6d73c3a408bdcc48 226 SUPERFAMILY SSF52540 1 221 1.12E-74 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS01075 c356daea9bcf46cc6d73c3a408bdcc48 226 SMART SM00382 30 217 4.1E-15 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS01075 c356daea9bcf46cc6d73c3a408bdcc48 226 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AUP74_RS02710 c82fdc55918a2a632850e578958e31d3 288 SUPERFAMILY SSF48452 176 257 1.56E-11 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS02710 c82fdc55918a2a632850e578958e31d3 288 SUPERFAMILY SSF54001 41 115 2.29E-6 T 11-11-2016 AUP74_RS02710 c82fdc55918a2a632850e578958e31d3 288 SMART SM00028 176 209 21.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS02710 c82fdc55918a2a632850e578958e31d3 288 SMART SM00028 210 243 1.5 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS02710 c82fdc55918a2a632850e578958e31d3 288 Pfam PF01841 Transglutaminase-like superfamily 48 141 1.7E-5 T 11-11-2016 IPR002931 Transglutaminase-like AUP74_RS02710 c82fdc55918a2a632850e578958e31d3 288 Gene3D G3DSA:1.25.40.10 178 258 7.0E-12 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS04410 420f0efdfd3cca2142c57ca26b88bc65 156 Pfam PF00430 ATP synthase B/B' CF(0) 6 136 2.7E-37 T 11-11-2016 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 AUP74_RS04410 420f0efdfd3cca2142c57ca26b88bc65 156 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 10 156 2.8E-51 T 11-11-2016 IPR005864 ATPase, F0 complex, subunit B, bacterial GO:0015078|GO:0015986|GO:0045263 AUP74_RS04410 420f0efdfd3cca2142c57ca26b88bc65 156 SUPERFAMILY SSF81573 63 121 6.67E-15 T 11-11-2016 IPR028987 F-type ATP synthase subunit B-like, membrane domain AUP74_RS04410 420f0efdfd3cca2142c57ca26b88bc65 156 Gene3D G3DSA:1.20.5.620 63 122 6.5E-22 T 11-11-2016 IPR028987 F-type ATP synthase subunit B-like, membrane domain AUP74_RS04410 420f0efdfd3cca2142c57ca26b88bc65 156 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 156 12.961 T 11-11-2016 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 AUP74_RS11740 199def481fb662a8d5fe104bce70dfaf 382 Pfam PF13439 Glycosyltransferase Family 4 90 178 2.2E-12 T 11-11-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AUP74_RS11740 199def481fb662a8d5fe104bce70dfaf 382 SUPERFAMILY SSF53756 20 375 2.39E-65 T 11-11-2016 AUP74_RS11740 199def481fb662a8d5fe104bce70dfaf 382 Pfam PF00534 Glycosyl transferases group 1 198 353 9.3E-32 T 11-11-2016 IPR001296 Glycosyl transferase, family 1 AUP74_RS11740 199def481fb662a8d5fe104bce70dfaf 382 Gene3D G3DSA:3.40.50.2000 168 351 2.2E-22 T 11-11-2016 AUP74_RS16555 010f530628d7da6b5224daaa95c369d2 400 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 11-11-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 AUP74_RS16555 010f530628d7da6b5224daaa95c369d2 400 SUPERFAMILY SSF47005 106 146 4.05E-11 T 11-11-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 AUP74_RS16555 010f530628d7da6b5224daaa95c369d2 400 SUPERFAMILY SSF51230 1 95 3.27E-24 T 11-11-2016 IPR011053 Single hybrid motif AUP74_RS16555 010f530628d7da6b5224daaa95c369d2 400 SUPERFAMILY SSF52777 170 399 4.89E-87 T 11-11-2016 AUP74_RS16555 010f530628d7da6b5224daaa95c369d2 400 Gene3D G3DSA:4.10.320.10 106 154 4.0E-17 T 11-11-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 AUP74_RS16555 010f530628d7da6b5224daaa95c369d2 400 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 3 400 3.6E-183 T 11-11-2016 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 AUP74_RS16555 010f530628d7da6b5224daaa95c369d2 400 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 170 398 8.5E-81 T 11-11-2016 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 AUP74_RS16555 010f530628d7da6b5224daaa95c369d2 400 Pfam PF00364 Biotin-requiring enzyme 4 75 2.9E-19 T 11-11-2016 IPR000089 Biotin/lipoyl attachment AUP74_RS16555 010f530628d7da6b5224daaa95c369d2 400 Gene3D G3DSA:2.40.50.100 1 96 1.3E-24 T 11-11-2016 AUP74_RS16555 010f530628d7da6b5224daaa95c369d2 400 Pfam PF02817 e3 binding domain 111 143 9.1E-15 T 11-11-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 AUP74_RS16555 010f530628d7da6b5224daaa95c369d2 400 Gene3D G3DSA:3.30.559.10 162 398 1.9E-89 T 11-11-2016 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 AUP74_RS09510 7ce27ca3861529f011f76116fb9d91d1 284 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 27 115 5.2E-29 T 11-11-2016 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 AUP74_RS09510 7ce27ca3861529f011f76116fb9d91d1 284 PIRSF PIRSF006250 10 284 7.1E-99 T 11-11-2016 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 AUP74_RS09510 7ce27ca3861529f011f76116fb9d91d1 284 SUPERFAMILY SSF54675 11 116 5.1E-34 T 11-11-2016 AUP74_RS09510 7ce27ca3861529f011f76116fb9d91d1 284 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 118 281 3.6E-53 T 11-11-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 AUP74_RS09510 7ce27ca3861529f011f76116fb9d91d1 284 Gene3D G3DSA:3.90.1170.20 13 137 2.6E-52 T 11-11-2016 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 AUP74_RS09510 7ce27ca3861529f011f76116fb9d91d1 284 Gene3D G3DSA:3.20.20.70 138 271 2.6E-54 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS09510 7ce27ca3861529f011f76116fb9d91d1 284 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 19 282 2.3E-93 T 11-11-2016 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 AUP74_RS09510 7ce27ca3861529f011f76116fb9d91d1 284 SUPERFAMILY SSF51690 118 282 2.79E-55 T 11-11-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 AUP74_RS10555 2572c9a0df025b1dbc36758ea60efdac 309 SUPERFAMILY SSF53335 5 292 2.55E-34 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS10555 2572c9a0df025b1dbc36758ea60efdac 309 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 22 305 2.5E-61 T 11-11-2016 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 AUP74_RS10555 2572c9a0df025b1dbc36758ea60efdac 309 Gene3D G3DSA:3.40.50.150 77 305 7.8E-37 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS00755 d9351b47a8d6a51047f046d01e359b18 878 Pfam PF07715 TonB-dependent Receptor Plug Domain 55 174 7.0E-23 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS00755 d9351b47a8d6a51047f046d01e359b18 878 Gene3D G3DSA:2.170.130.10 43 174 7.7E-33 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS00755 d9351b47a8d6a51047f046d01e359b18 878 SUPERFAMILY SSF56935 41 239 2.66E-104 T 11-11-2016 AUP74_RS00755 d9351b47a8d6a51047f046d01e359b18 878 SUPERFAMILY SSF56935 386 675 2.66E-104 T 11-11-2016 AUP74_RS00755 d9351b47a8d6a51047f046d01e359b18 878 SUPERFAMILY SSF56935 308 356 2.66E-104 T 11-11-2016 AUP74_RS00755 d9351b47a8d6a51047f046d01e359b18 878 SUPERFAMILY SSF56935 712 878 2.66E-104 T 11-11-2016 AUP74_RS00755 d9351b47a8d6a51047f046d01e359b18 878 Gene3D G3DSA:2.40.170.20 175 237 1.8E-93 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS00755 d9351b47a8d6a51047f046d01e359b18 878 Gene3D G3DSA:2.40.170.20 285 878 1.8E-93 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS00755 d9351b47a8d6a51047f046d01e359b18 878 Pfam PF00593 TonB dependent receptor 568 876 1.2E-29 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS02090 214d95c7ef3edcfe3591360bad7eb046 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 279 1.1E-20 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AUP74_RS02090 214d95c7ef3edcfe3591360bad7eb046 288 SUPERFAMILY SSF161098 8 288 3.18E-71 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AUP74_RS02090 214d95c7ef3edcfe3591360bad7eb046 288 Gene3D G3DSA:1.10.3720.10 9 275 1.3E-64 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AUP74_RS16525 3ff64d3721c3b1be5b8762522e5c5f58 490 Gene3D G3DSA:3.50.50.60 10 145 1.8E-32 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS16525 3ff64d3721c3b1be5b8762522e5c5f58 490 SUPERFAMILY SSF55424 352 468 9.28E-36 T 11-11-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 AUP74_RS16525 3ff64d3721c3b1be5b8762522e5c5f58 490 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 334 3.0E-57 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS16525 3ff64d3721c3b1be5b8762522e5c5f58 490 Gene3D G3DSA:3.30.390.30 351 467 6.5E-39 T 11-11-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AUP74_RS16525 3ff64d3721c3b1be5b8762522e5c5f58 490 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 141 159 3.5E-28 T 11-11-2016 AUP74_RS16525 3ff64d3721c3b1be5b8762522e5c5f58 490 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 3.5E-28 T 11-11-2016 AUP74_RS16525 3ff64d3721c3b1be5b8762522e5c5f58 490 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 299 321 3.5E-28 T 11-11-2016 AUP74_RS16525 3ff64d3721c3b1be5b8762522e5c5f58 490 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 184 202 3.5E-28 T 11-11-2016 AUP74_RS16525 3ff64d3721c3b1be5b8762522e5c5f58 490 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 272 288 3.5E-28 T 11-11-2016 AUP74_RS16525 3ff64d3721c3b1be5b8762522e5c5f58 490 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 144 153 3.1E-61 T 11-11-2016 AUP74_RS16525 3ff64d3721c3b1be5b8762522e5c5f58 490 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 184 209 3.1E-61 T 11-11-2016 AUP74_RS16525 3ff64d3721c3b1be5b8762522e5c5f58 490 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 314 321 3.1E-61 T 11-11-2016 AUP74_RS16525 3ff64d3721c3b1be5b8762522e5c5f58 490 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 439 459 3.1E-61 T 11-11-2016 AUP74_RS16525 3ff64d3721c3b1be5b8762522e5c5f58 490 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 273 287 3.1E-61 T 11-11-2016 AUP74_RS16525 3ff64d3721c3b1be5b8762522e5c5f58 490 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 352 373 3.1E-61 T 11-11-2016 AUP74_RS16525 3ff64d3721c3b1be5b8762522e5c5f58 490 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 3.1E-61 T 11-11-2016 AUP74_RS16525 3ff64d3721c3b1be5b8762522e5c5f58 490 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 42 57 3.1E-61 T 11-11-2016 AUP74_RS16525 3ff64d3721c3b1be5b8762522e5c5f58 490 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 417 432 3.1E-61 T 11-11-2016 AUP74_RS16525 3ff64d3721c3b1be5b8762522e5c5f58 490 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 43 53 - T 11-11-2016 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 AUP74_RS16525 3ff64d3721c3b1be5b8762522e5c5f58 490 SUPERFAMILY SSF51905 11 378 1.91E-56 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS16525 3ff64d3721c3b1be5b8762522e5c5f58 490 PIRSF PIRSF000350 1 471 3.5E-99 T 11-11-2016 AUP74_RS16525 3ff64d3721c3b1be5b8762522e5c5f58 490 Gene3D G3DSA:3.50.50.60 146 340 1.8E-48 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS16525 3ff64d3721c3b1be5b8762522e5c5f58 490 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 356 460 4.0E-29 T 11-11-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AUP74_RS16620 2031d81876c8c8afe530981aeb208997 397 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 10 394 6.4E-125 T 11-11-2016 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like AUP74_RS16620 2031d81876c8c8afe530981aeb208997 397 SUPERFAMILY SSF51905 340 397 2.4E-59 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS16620 2031d81876c8c8afe530981aeb208997 397 SUPERFAMILY SSF51905 6 192 2.4E-59 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS16620 2031d81876c8c8afe530981aeb208997 397 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 159 168 3.5E-8 T 11-11-2016 AUP74_RS16620 2031d81876c8c8afe530981aeb208997 397 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 365 372 3.5E-8 T 11-11-2016 AUP74_RS16620 2031d81876c8c8afe530981aeb208997 397 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 3.5E-8 T 11-11-2016 AUP74_RS16620 2031d81876c8c8afe530981aeb208997 397 SUPERFAMILY SSF160996 194 341 3.66E-37 T 11-11-2016 AUP74_RS16620 2031d81876c8c8afe530981aeb208997 397 Pfam PF03486 HI0933-like protein 9 395 1.1E-146 T 11-11-2016 AUP74_RS16620 2031d81876c8c8afe530981aeb208997 397 Gene3D G3DSA:3.50.50.60 6 190 1.1E-51 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS16620 2031d81876c8c8afe530981aeb208997 397 Gene3D G3DSA:3.50.50.60 342 395 1.1E-51 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS16620 2031d81876c8c8afe530981aeb208997 397 Gene3D G3DSA:2.40.30.10 192 272 3.6E-27 T 11-11-2016 AUP74_RS16620 2031d81876c8c8afe530981aeb208997 397 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 3.9E-5 T 11-11-2016 AUP74_RS16620 2031d81876c8c8afe530981aeb208997 397 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 3.9E-5 T 11-11-2016 AUP74_RS16620 2031d81876c8c8afe530981aeb208997 397 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 350 372 3.9E-5 T 11-11-2016 AUP74_RS16620 2031d81876c8c8afe530981aeb208997 397 Gene3D G3DSA:1.10.8.260 273 324 1.1E-10 T 11-11-2016 IPR023166 HI0933 insert-like domain AUP74_RS08580 e9c477e903a4c1e4d6f4796809f39b3a 661 SUPERFAMILY SSF56801 18 652 4.97E-181 T 11-11-2016 AUP74_RS08580 e9c477e903a4c1e4d6f4796809f39b3a 661 Gene3D G3DSA:3.30.300.30 527 638 1.8E-25 T 11-11-2016 AUP74_RS08580 e9c477e903a4c1e4d6f4796809f39b3a 661 Gene3D G3DSA:3.40.50.980 276 432 2.7E-30 T 11-11-2016 AUP74_RS08580 e9c477e903a4c1e4d6f4796809f39b3a 661 Pfam PF13193 AMP-binding enzyme C-terminal domain 540 618 6.0E-23 T 11-11-2016 IPR025110 AMP-binding enzyme C-terminal domain AUP74_RS08580 e9c477e903a4c1e4d6f4796809f39b3a 661 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 11 654 50.974 T 11-11-2016 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: R-HSA-71384 AUP74_RS08580 e9c477e903a4c1e4d6f4796809f39b3a 661 Pfam PF00501 AMP-binding enzyme 92 531 3.4E-89 T 11-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 AUP74_RS08580 e9c477e903a4c1e4d6f4796809f39b3a 661 ProSitePatterns PS00455 Putative AMP-binding domain signature. 270 281 - T 11-11-2016 IPR020845 AMP-binding, conserved site AUP74_RS08580 e9c477e903a4c1e4d6f4796809f39b3a 661 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 29 651 4.6E-296 T 11-11-2016 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: R-HSA-71384 AUP74_RS08580 e9c477e903a4c1e4d6f4796809f39b3a 661 Gene3D G3DSA:3.40.50.980 89 275 4.2E-41 T 11-11-2016 AUP74_RS08580 e9c477e903a4c1e4d6f4796809f39b3a 661 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 33 90 2.1E-21 T 11-11-2016 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 AUP74_RS08580 e9c477e903a4c1e4d6f4796809f39b3a 661 Gene3D G3DSA:2.30.38.10 448 524 7.1E-7 T 11-11-2016 AUP74_RS07035 b9bfdff3fd1ba9e6c1fec6f0762ab51d 85 SUPERFAMILY SSF110324 2 80 5.23E-35 T 11-11-2016 AUP74_RS07035 b9bfdff3fd1ba9e6c1fec6f0762ab51d 85 Pfam PF01016 Ribosomal L27 protein 2 82 7.4E-40 T 11-11-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS07035 b9bfdff3fd1ba9e6c1fec6f0762ab51d 85 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 71 3.0E-16 T 11-11-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS07035 b9bfdff3fd1ba9e6c1fec6f0762ab51d 85 Gene3D G3DSA:2.40.50.100 20 82 1.0E-32 T 11-11-2016 AUP74_RS07035 b9bfdff3fd1ba9e6c1fec6f0762ab51d 85 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 11-11-2016 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS07035 b9bfdff3fd1ba9e6c1fec6f0762ab51d 85 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 85 29.548 T 11-11-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS07035 b9bfdff3fd1ba9e6c1fec6f0762ab51d 85 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 82 2.1E-43 T 11-11-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS07035 b9bfdff3fd1ba9e6c1fec6f0762ab51d 85 PRINTS PR00063 Ribosomal protein L27 signature 29 53 1.7E-39 T 11-11-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS07035 b9bfdff3fd1ba9e6c1fec6f0762ab51d 85 PRINTS PR00063 Ribosomal protein L27 signature 54 78 1.7E-39 T 11-11-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS07035 b9bfdff3fd1ba9e6c1fec6f0762ab51d 85 PRINTS PR00063 Ribosomal protein L27 signature 4 28 1.7E-39 T 11-11-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS14980 cc4ef8ffcd0b8d808a72908df4854240 464 Pfam PF03575 Peptidase family S51 229 387 9.3E-11 T 11-11-2016 IPR005320 Peptidase S51 GO:0006508|GO:0008236 AUP74_RS14980 cc4ef8ffcd0b8d808a72908df4854240 464 SUPERFAMILY SSF89260 24 130 2.22E-14 T 11-11-2016 AUP74_RS14980 cc4ef8ffcd0b8d808a72908df4854240 464 SUPERFAMILY SSF52317 202 400 3.48E-15 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS14980 cc4ef8ffcd0b8d808a72908df4854240 464 Gene3D G3DSA:2.60.120.380 21 130 4.4E-21 T 11-11-2016 AUP74_RS14980 cc4ef8ffcd0b8d808a72908df4854240 464 Gene3D G3DSA:3.40.50.880 184 409 7.4E-22 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS11010 d207b59e4dcd5564d953244f8f0e7f6b 545 ProSitePatterns PS00455 Putative AMP-binding domain signature. 193 204 - T 11-11-2016 IPR020845 AMP-binding, conserved site AUP74_RS11010 d207b59e4dcd5564d953244f8f0e7f6b 545 Pfam PF00501 AMP-binding enzyme 12 442 3.1E-109 T 11-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 AUP74_RS11010 d207b59e4dcd5564d953244f8f0e7f6b 545 SUPERFAMILY SSF56801 6 542 7.85E-148 T 11-11-2016 AUP74_RS11010 d207b59e4dcd5564d953244f8f0e7f6b 545 Pfam PF13193 AMP-binding enzyme C-terminal domain 451 525 3.1E-20 T 11-11-2016 IPR025110 AMP-binding enzyme C-terminal domain AUP74_RS11010 d207b59e4dcd5564d953244f8f0e7f6b 545 Gene3D G3DSA:3.30.300.30 437 534 2.0E-31 T 11-11-2016 AUP74_RS11010 d207b59e4dcd5564d953244f8f0e7f6b 545 Gene3D G3DSA:2.30.38.10 362 433 5.3E-31 T 11-11-2016 AUP74_RS11010 d207b59e4dcd5564d953244f8f0e7f6b 545 Gene3D G3DSA:3.40.50.980 5 133 3.1E-35 T 11-11-2016 AUP74_RS11010 d207b59e4dcd5564d953244f8f0e7f6b 545 Gene3D G3DSA:3.40.50.980 167 198 3.1E-35 T 11-11-2016 AUP74_RS11010 d207b59e4dcd5564d953244f8f0e7f6b 545 Gene3D G3DSA:3.40.50.980 199 361 2.4E-42 T 11-11-2016 AUP74_RS06195 c4fc48a472aff2b75081961fda282c24 222 SUPERFAMILY SSF55469 23 220 7.33E-41 T 11-11-2016 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AUP74_RS06195 c4fc48a472aff2b75081961fda282c24 222 Gene3D G3DSA:3.40.109.10 23 220 3.0E-45 T 11-11-2016 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AUP74_RS06195 c4fc48a472aff2b75081961fda282c24 222 Pfam PF00881 Nitroreductase family 31 199 1.3E-24 T 11-11-2016 IPR029479 Nitroreductase Reactome: R-HSA-209968 AUP74_RS06365 c9af19536579274e6c0f6422e3ac66d1 242 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 8 237 2.8E-49 T 11-11-2016 AUP74_RS06365 c9af19536579274e6c0f6422e3ac66d1 242 Gene3D G3DSA:3.40.50.720 2 240 1.3E-70 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS06365 c9af19536579274e6c0f6422e3ac66d1 242 SUPERFAMILY SSF51735 2 240 8.0E-69 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS06365 c9af19536579274e6c0f6422e3ac66d1 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 6.2E-11 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS06365 c9af19536579274e6c0f6422e3ac66d1 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 6.2E-11 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS06365 c9af19536579274e6c0f6422e3ac66d1 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 6.2E-11 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS06365 c9af19536579274e6c0f6422e3ac66d1 242 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 11-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AUP74_RS06365 c9af19536579274e6c0f6422e3ac66d1 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 8.9E-34 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS06365 c9af19536579274e6c0f6422e3ac66d1 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 8.9E-34 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS06365 c9af19536579274e6c0f6422e3ac66d1 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 8.9E-34 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS06365 c9af19536579274e6c0f6422e3ac66d1 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 8.9E-34 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS06365 c9af19536579274e6c0f6422e3ac66d1 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 8.9E-34 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS06365 c9af19536579274e6c0f6422e3ac66d1 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 223 8.9E-34 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS16820 79577b830e74e652b8c1dc1cc2e741c7 396 SUPERFAMILY SSF53901 9 273 1.86E-82 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS16820 79577b830e74e652b8c1dc1cc2e741c7 396 ProSitePatterns PS00099 Thiolases active site. 377 390 - T 11-11-2016 IPR020610 Thiolase, active site GO:0008152|GO:0016747 AUP74_RS16820 79577b830e74e652b8c1dc1cc2e741c7 396 Gene3D G3DSA:3.40.47.10 9 128 3.6E-71 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS16820 79577b830e74e652b8c1dc1cc2e741c7 396 Gene3D G3DSA:3.40.47.10 199 278 3.6E-71 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS16820 79577b830e74e652b8c1dc1cc2e741c7 396 Gene3D G3DSA:3.40.47.10 280 395 3.3E-59 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS16820 79577b830e74e652b8c1dc1cc2e741c7 396 Gene3D G3DSA:3.40.47.10 147 198 3.3E-59 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS16820 79577b830e74e652b8c1dc1cc2e741c7 396 PIRSF PIRSF000429 4 396 1.8E-115 T 11-11-2016 IPR002155 Thiolase GO:0008152|GO:0016747 AUP74_RS16820 79577b830e74e652b8c1dc1cc2e741c7 396 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 89 107 - T 11-11-2016 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 AUP74_RS16820 79577b830e74e652b8c1dc1cc2e741c7 396 SUPERFAMILY SSF53901 275 395 6.26E-40 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS16820 79577b830e74e652b8c1dc1cc2e741c7 396 Pfam PF00108 Thiolase, N-terminal domain 9 266 1.3E-91 T 11-11-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 AUP74_RS16820 79577b830e74e652b8c1dc1cc2e741c7 396 Pfam PF02803 Thiolase, C-terminal domain 274 395 4.0E-43 T 11-11-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 AUP74_RS16820 79577b830e74e652b8c1dc1cc2e741c7 396 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 11 394 8.9E-128 T 11-11-2016 IPR002155 Thiolase GO:0008152|GO:0016747 AUP74_RS07190 37be62fe2b64e4f0672d8f2a9f375614 870 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 868 0.0 T 11-11-2016 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 AUP74_RS07190 37be62fe2b64e4f0672d8f2a9f375614 870 SMART SM01086 779 868 1.6E-35 T 11-11-2016 IPR019489 Clp ATPase, C-terminal AUP74_RS07190 37be62fe2b64e4f0672d8f2a9f375614 870 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 605 623 2.4E-42 T 11-11-2016 IPR001270 ClpA/B family GO:0005524 AUP74_RS07190 37be62fe2b64e4f0672d8f2a9f375614 870 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 650 668 2.4E-42 T 11-11-2016 IPR001270 ClpA/B family GO:0005524 AUP74_RS07190 37be62fe2b64e4f0672d8f2a9f375614 870 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 712 726 2.4E-42 T 11-11-2016 IPR001270 ClpA/B family GO:0005524 AUP74_RS07190 37be62fe2b64e4f0672d8f2a9f375614 870 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 679 697 2.4E-42 T 11-11-2016 IPR001270 ClpA/B family GO:0005524 AUP74_RS07190 37be62fe2b64e4f0672d8f2a9f375614 870 Gene3D G3DSA:3.40.50.300 160 342 9.5E-48 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS07190 37be62fe2b64e4f0672d8f2a9f375614 870 Pfam PF07724 AAA domain (Cdc48 subfamily) 600 773 1.2E-55 T 11-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 AUP74_RS07190 37be62fe2b64e4f0672d8f2a9f375614 870 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 779 858 2.8E-25 T 11-11-2016 IPR019489 Clp ATPase, C-terminal AUP74_RS07190 37be62fe2b64e4f0672d8f2a9f375614 870 SUPERFAMILY SSF52540 159 549 9.29E-98 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS07190 37be62fe2b64e4f0672d8f2a9f375614 870 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 294 306 - T 11-11-2016 IPR018368 ClpA/B, conserved site 1 GO:0005524 AUP74_RS07190 37be62fe2b64e4f0672d8f2a9f375614 870 SUPERFAMILY SSF81923 4 156 8.04E-38 T 11-11-2016 IPR004176 Clp, N-terminal GO:0019538 AUP74_RS07190 37be62fe2b64e4f0672d8f2a9f375614 870 Gene3D G3DSA:1.10.1780.10 2 148 9.5E-38 T 11-11-2016 IPR004176 Clp, N-terminal GO:0019538 AUP74_RS07190 37be62fe2b64e4f0672d8f2a9f375614 870 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 203 320 1.4E-12 T 11-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 AUP74_RS07190 37be62fe2b64e4f0672d8f2a9f375614 870 SMART SM00382 198 343 5.6E-11 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS07190 37be62fe2b64e4f0672d8f2a9f375614 870 SMART SM00382 601 751 2.9E-11 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS07190 37be62fe2b64e4f0672d8f2a9f375614 870 SUPERFAMILY SSF52540 550 866 1.18E-83 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS07190 37be62fe2b64e4f0672d8f2a9f375614 870 Gene3D G3DSA:1.10.8.60 344 428 1.5E-36 T 11-11-2016 AUP74_RS07190 37be62fe2b64e4f0672d8f2a9f375614 870 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 635 653 - T 11-11-2016 IPR028299 ClpA/B, conserved site 2 AUP74_RS07190 37be62fe2b64e4f0672d8f2a9f375614 870 Gene3D G3DSA:3.40.50.300 554 727 8.8E-59 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS07190 37be62fe2b64e4f0672d8f2a9f375614 870 Gene3D G3DSA:3.40.50.300 762 789 8.8E-59 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS07190 37be62fe2b64e4f0672d8f2a9f375614 870 Gene3D G3DSA:1.10.8.60 790 869 3.2E-29 T 11-11-2016 AUP74_RS07190 37be62fe2b64e4f0672d8f2a9f375614 870 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 94 145 3.6E-8 T 11-11-2016 IPR004176 Clp, N-terminal GO:0019538 AUP74_RS07190 37be62fe2b64e4f0672d8f2a9f375614 870 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 67 2.7E-11 T 11-11-2016 IPR004176 Clp, N-terminal GO:0019538 AUP74_RS02695 86ae3c55c31b82885c645588a5fcc3d1 534 Pfam PF11356 Type II secretion system protein C 299 371 1.1E-10 T 11-11-2016 IPR024961 Type II secretion system protein C, N-terminal AUP74_RS02695 86ae3c55c31b82885c645588a5fcc3d1 534 Gene3D G3DSA:2.30.42.10 461 512 2.2E-4 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS02695 86ae3c55c31b82885c645588a5fcc3d1 534 Gene3D G3DSA:3.40.30.10 114 281 7.0E-32 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS02695 86ae3c55c31b82885c645588a5fcc3d1 534 Pfam PF13462 Thioredoxin 117 278 9.7E-24 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS02695 86ae3c55c31b82885c645588a5fcc3d1 534 SUPERFAMILY SSF50156 448 508 4.44E-5 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS02695 86ae3c55c31b82885c645588a5fcc3d1 534 SUPERFAMILY SSF52833 110 277 4.86E-26 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS04180 bc7f3294b474b9027ffa0d49f55f4a84 423 SUPERFAMILY SSF48452 260 404 4.56E-19 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS04180 bc7f3294b474b9027ffa0d49f55f4a84 423 Gene3D G3DSA:3.30.2010.10 58 142 4.8E-20 T 11-11-2016 AUP74_RS04180 bc7f3294b474b9027ffa0d49f55f4a84 423 Pfam PF01435 Peptidase family M48 62 243 1.0E-34 T 11-11-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 AUP74_RS04180 bc7f3294b474b9027ffa0d49f55f4a84 423 Pfam PF13432 Tetratricopeptide repeat 278 340 8.9E-5 T 11-11-2016 AUP74_RS04180 bc7f3294b474b9027ffa0d49f55f4a84 423 Pfam PF13432 Tetratricopeptide repeat 346 400 7.7E-6 T 11-11-2016 AUP74_RS04180 bc7f3294b474b9027ffa0d49f55f4a84 423 Gene3D G3DSA:1.25.40.10 259 404 3.6E-20 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS04180 bc7f3294b474b9027ffa0d49f55f4a84 423 SMART SM00028 274 307 57.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS04180 bc7f3294b474b9027ffa0d49f55f4a84 423 SMART SM00028 342 375 4.1 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS04180 bc7f3294b474b9027ffa0d49f55f4a84 423 SMART SM00028 308 341 4.6 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS04180 bc7f3294b474b9027ffa0d49f55f4a84 423 SMART SM00028 377 408 44.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS05560 39e53d9e77ce536a5099c76d55d7a357 487 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 10 431 2.0E-174 T 11-11-2016 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 AUP74_RS05560 39e53d9e77ce536a5099c76d55d7a357 487 SUPERFAMILY SSF50475 3 322 3.14E-128 T 11-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 AUP74_RS05560 39e53d9e77ce536a5099c76d55d7a357 487 SUPERFAMILY SSF143968 323 487 7.45E-67 T 11-11-2016 AUP74_RS05560 39e53d9e77ce536a5099c76d55d7a357 487 Hamap MF_01636 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [ubiD]. 1 487 71.357 T 11-11-2016 IPR023677 UbiD decarboxylyase, bacteria GO:0005886|GO:0006744|GO:0008694 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 AUP74_RS05560 39e53d9e77ce536a5099c76d55d7a357 487 Gene3D G3DSA:1.20.5.570 455 487 1.5E-17 T 11-11-2016 AUP74_RS05560 39e53d9e77ce536a5099c76d55d7a357 487 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 455 1.4E-172 T 11-11-2016 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 AUP74_RS05560 39e53d9e77ce536a5099c76d55d7a357 487 Gene3D G3DSA:3.40.1670.10 337 454 8.5E-54 T 11-11-2016 AUP74_RS05245 99e463ead1b77e3b4bf7b723571cb70e 1065 SUPERFAMILY SSF52540 439 495 2.59E-20 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05245 99e463ead1b77e3b4bf7b723571cb70e 1065 SUPERFAMILY SSF52540 588 687 2.59E-20 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05245 99e463ead1b77e3b4bf7b723571cb70e 1065 SUPERFAMILY SSF52540 747 893 2.59E-20 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05245 99e463ead1b77e3b4bf7b723571cb70e 1065 SMART SM00490 792 884 0.0023 T 11-11-2016 IPR001650 Helicase, C-terminal AUP74_RS05245 99e463ead1b77e3b4bf7b723571cb70e 1065 Gene3D G3DSA:3.40.50.300 807 908 8.4E-16 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05245 99e463ead1b77e3b4bf7b723571cb70e 1065 Pfam PF00271 Helicase conserved C-terminal domain 808 883 9.0E-7 T 11-11-2016 IPR001650 Helicase, C-terminal AUP74_RS05245 99e463ead1b77e3b4bf7b723571cb70e 1065 Gene3D G3DSA:3.40.50.300 600 690 1.5E-5 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05245 99e463ead1b77e3b4bf7b723571cb70e 1065 Gene3D G3DSA:3.40.50.300 439 514 1.5E-5 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS06975 6cad48deb72aebc4b41d28456318d306 725 Gene3D G3DSA:1.10.439.10 38 157 8.2E-34 T 11-11-2016 IPR023343 Penicillin amidase type, domain1 GO:0016811 AUP74_RS06975 6cad48deb72aebc4b41d28456318d306 725 Pfam PF01804 Penicillin amidase 43 704 2.4E-110 T 11-11-2016 IPR002692 Penicillin/cephalosporin acylase GO:0016787|GO:0017000 AUP74_RS06975 6cad48deb72aebc4b41d28456318d306 725 SUPERFAMILY SSF56235 38 712 1.13E-151 T 11-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal AUP74_RS06975 6cad48deb72aebc4b41d28456318d306 725 Gene3D G3DSA:2.30.120.10 289 352 1.7E-14 T 11-11-2016 AUP74_RS06975 6cad48deb72aebc4b41d28456318d306 725 Gene3D G3DSA:3.60.20.10 158 288 7.3E-66 T 11-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal AUP74_RS06975 6cad48deb72aebc4b41d28456318d306 725 Gene3D G3DSA:3.60.20.10 363 562 7.3E-66 T 11-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal AUP74_RS13740 bdb26d99060b080aff26765e74e7522d 261 Pfam PF00106 short chain dehydrogenase 7 193 4.7E-35 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS13740 bdb26d99060b080aff26765e74e7522d 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 11-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AUP74_RS13740 bdb26d99060b080aff26765e74e7522d 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 4.9E-11 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS13740 bdb26d99060b080aff26765e74e7522d 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.9E-11 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS13740 bdb26d99060b080aff26765e74e7522d 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 4.9E-11 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS13740 bdb26d99060b080aff26765e74e7522d 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 4.9E-11 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS13740 bdb26d99060b080aff26765e74e7522d 261 SUPERFAMILY SSF51735 4 253 1.86E-52 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS13740 bdb26d99060b080aff26765e74e7522d 261 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 183 0.0014 T 11-11-2016 AUP74_RS13740 bdb26d99060b080aff26765e74e7522d 261 Gene3D G3DSA:3.40.50.720 6 218 1.4E-46 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS03340 9d12a0fa7549ea4802c62cde700bb796 960 SMART SM00487 33 230 1.3E-21 T 11-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain AUP74_RS03340 9d12a0fa7549ea4802c62cde700bb796 960 Pfam PF00176 SNF2 family N-terminal domain 53 256 8.2E-33 T 11-11-2016 IPR000330 SNF2-related, N-terminal domain GO:0005524 AUP74_RS03340 9d12a0fa7549ea4802c62cde700bb796 960 Gene3D G3DSA:3.40.50.300 398 580 1.3E-26 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03340 9d12a0fa7549ea4802c62cde700bb796 960 Pfam PF00271 Helicase conserved C-terminal domain 436 548 2.6E-15 T 11-11-2016 IPR001650 Helicase, C-terminal AUP74_RS03340 9d12a0fa7549ea4802c62cde700bb796 960 SUPERFAMILY SSF52540 391 443 1.72E-41 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03340 9d12a0fa7549ea4802c62cde700bb796 960 SUPERFAMILY SSF52540 157 215 1.72E-41 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03340 9d12a0fa7549ea4802c62cde700bb796 960 SUPERFAMILY SSF52540 472 592 1.72E-41 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03340 9d12a0fa7549ea4802c62cde700bb796 960 Gene3D G3DSA:3.40.50.300 34 209 2.0E-24 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03340 9d12a0fa7549ea4802c62cde700bb796 960 SUPERFAMILY SSF52540 33 249 3.03E-40 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03340 9d12a0fa7549ea4802c62cde700bb796 960 SMART SM00490 469 548 4.4E-16 T 11-11-2016 IPR001650 Helicase, C-terminal AUP74_RS14570 d5d642bcef1a4124a690c5da5204a0be 482 SUPERFAMILY SSF51905 98 401 1.11E-34 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS14570 d5d642bcef1a4124a690c5da5204a0be 482 SUPERFAMILY SSF57802 3 56 1.85E-21 T 11-11-2016 AUP74_RS14570 d5d642bcef1a4124a690c5da5204a0be 482 Gene3D G3DSA:2.20.28.10 2 56 1.7E-24 T 11-11-2016 IPR004039 Rubredoxin-type fold AUP74_RS14570 d5d642bcef1a4124a690c5da5204a0be 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 329 343 1.5E-15 T 11-11-2016 AUP74_RS14570 d5d642bcef1a4124a690c5da5204a0be 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 210 219 1.5E-15 T 11-11-2016 AUP74_RS14570 d5d642bcef1a4124a690c5da5204a0be 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 243 268 1.5E-15 T 11-11-2016 AUP74_RS14570 d5d642bcef1a4124a690c5da5204a0be 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 98 120 1.5E-15 T 11-11-2016 AUP74_RS14570 d5d642bcef1a4124a690c5da5204a0be 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 368 375 1.5E-15 T 11-11-2016 AUP74_RS14570 d5d642bcef1a4124a690c5da5204a0be 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 456 471 1.5E-15 T 11-11-2016 AUP74_RS14570 d5d642bcef1a4124a690c5da5204a0be 482 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 99 380 2.0E-51 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS14570 d5d642bcef1a4124a690c5da5204a0be 482 Gene3D G3DSA:3.50.50.60 98 201 1.6E-20 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS14570 d5d642bcef1a4124a690c5da5204a0be 482 Gene3D G3DSA:3.50.50.60 202 386 1.7E-39 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS14570 d5d642bcef1a4124a690c5da5204a0be 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 353 375 3.1E-20 T 11-11-2016 AUP74_RS14570 d5d642bcef1a4124a690c5da5204a0be 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 198 216 3.1E-20 T 11-11-2016 AUP74_RS14570 d5d642bcef1a4124a690c5da5204a0be 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 328 344 3.1E-20 T 11-11-2016 AUP74_RS14570 d5d642bcef1a4124a690c5da5204a0be 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 99 118 3.1E-20 T 11-11-2016 AUP74_RS14570 d5d642bcef1a4124a690c5da5204a0be 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 243 261 3.1E-20 T 11-11-2016 AUP74_RS14570 d5d642bcef1a4124a690c5da5204a0be 482 Pfam PF00301 Rubredoxin 7 52 7.0E-22 T 11-11-2016 IPR024935 Rubredoxin domain GO:0005506 AUP74_RS14570 d5d642bcef1a4124a690c5da5204a0be 482 PRINTS PR00163 Rubredoxin signature 36 52 4.5E-8 T 11-11-2016 IPR024935 Rubredoxin domain GO:0005506 AUP74_RS14570 d5d642bcef1a4124a690c5da5204a0be 482 PRINTS PR00163 Rubredoxin signature 6 22 4.5E-8 T 11-11-2016 IPR024935 Rubredoxin domain GO:0005506 AUP74_RS14570 d5d642bcef1a4124a690c5da5204a0be 482 ProSitePatterns PS00202 Rubredoxin signature. 36 46 - T 11-11-2016 IPR018527 Rubredoxin, iron-binding site GO:0046872 AUP74_RS09015 1fa6e72ebc9af96f90ae5a83725c07fe 566 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 125 143 6.1E-72 T 11-11-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AUP74_RS09015 1fa6e72ebc9af96f90ae5a83725c07fe 566 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 369 387 6.1E-72 T 11-11-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AUP74_RS09015 1fa6e72ebc9af96f90ae5a83725c07fe 566 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 143 162 6.1E-72 T 11-11-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AUP74_RS09015 1fa6e72ebc9af96f90ae5a83725c07fe 566 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 240 256 6.1E-72 T 11-11-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AUP74_RS09015 1fa6e72ebc9af96f90ae5a83725c07fe 566 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 393 411 6.1E-72 T 11-11-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AUP74_RS09015 1fa6e72ebc9af96f90ae5a83725c07fe 566 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 53 78 6.1E-72 T 11-11-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AUP74_RS09015 1fa6e72ebc9af96f90ae5a83725c07fe 566 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 458 475 6.1E-72 T 11-11-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AUP74_RS09015 1fa6e72ebc9af96f90ae5a83725c07fe 566 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 434 449 6.1E-72 T 11-11-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AUP74_RS09015 1fa6e72ebc9af96f90ae5a83725c07fe 566 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 270 289 6.1E-72 T 11-11-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AUP74_RS09015 1fa6e72ebc9af96f90ae5a83725c07fe 566 ProSitePatterns PS00462 Gamma-glutamyltranspeptidase signature. 369 393 - T 11-11-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AUP74_RS09015 1fa6e72ebc9af96f90ae5a83725c07fe 566 SUPERFAMILY SSF56235 27 545 2.7E-166 T 11-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal AUP74_RS09015 1fa6e72ebc9af96f90ae5a83725c07fe 566 Pfam PF01019 Gamma-glutamyltranspeptidase 46 547 1.5E-162 T 11-11-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AUP74_RS09015 1fa6e72ebc9af96f90ae5a83725c07fe 566 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 34 544 1.6E-149 T 11-11-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AUP74_RS09050 ac85b6a87ba3d1f55793fa66b14e3461 389 Pfam PF01553 Acyltransferase 94 198 9.3E-10 T 11-11-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 AUP74_RS09050 ac85b6a87ba3d1f55793fa66b14e3461 389 SUPERFAMILY SSF69593 66 245 8.5E-7 T 11-11-2016 AUP74_RS09050 ac85b6a87ba3d1f55793fa66b14e3461 389 Gene3D G3DSA:3.40.1130.10 96 243 1.6E-4 T 11-11-2016 AUP74_RS10125 fbd6be684e1362586ba7d1fe1b9981de 64 Pfam PF13617 YnbE-like lipoprotein 9 61 3.3E-27 T 11-11-2016 IPR025985 YnbE-like lipoprotein AUP74_RS10125 fbd6be684e1362586ba7d1fe1b9981de 64 ProDom PD052969 LIPOPROTEIN PRECURSOR SIGNAL YNBE MEMBRANE OUTER POSSIBLE SIMILAR ECS2004 SO2063 22 64 2.0E-11 T 11-11-2016 AUP74_RS05090 bdcd31691348d22c3da22dadd4537d58 182 Gene3D G3DSA:3.10.180.10 1 172 1.8E-45 T 11-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AUP74_RS05090 bdcd31691348d22c3da22dadd4537d58 182 SUPERFAMILY SSF54593 1 142 1.3E-39 T 11-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AUP74_RS05090 bdcd31691348d22c3da22dadd4537d58 182 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 134 5.4E-18 T 11-11-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AUP74_RS05090 bdcd31691348d22c3da22dadd4537d58 182 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 114 133 - T 11-11-2016 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 AUP74_RS04295 0549f0b6aee55791d5c47fadd29ac654 323 Pfam PF13409 Glutathione S-transferase, N-terminal domain 62 157 1.2E-20 T 11-11-2016 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 AUP74_RS04295 0549f0b6aee55791d5c47fadd29ac654 323 SUPERFAMILY SSF47616 170 322 1.39E-38 T 11-11-2016 IPR010987 Glutathione S-transferase, C-terminal-like AUP74_RS04295 0549f0b6aee55791d5c47fadd29ac654 323 SUPERFAMILY SSF52833 41 161 1.34E-14 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS04295 0549f0b6aee55791d5c47fadd29ac654 323 Gene3D G3DSA:1.20.1050.10 178 288 9.0E-26 T 11-11-2016 IPR010987 Glutathione S-transferase, C-terminal-like AUP74_RS04295 0549f0b6aee55791d5c47fadd29ac654 323 PIRSF PIRSF015753 5 323 9.4E-134 T 11-11-2016 IPR016639 Glutathione S-transferase (GST) KEGG: 00480+2.5.1.18|KEGG: 00980+2.5.1.18|KEGG: 00982+2.5.1.18|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7533 AUP74_RS04295 0549f0b6aee55791d5c47fadd29ac654 323 Gene3D G3DSA:3.40.30.10 39 177 1.2E-20 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS04295 0549f0b6aee55791d5c47fadd29ac654 323 Pfam PF13410 Glutathione S-transferase, C-terminal domain 203 274 3.0E-15 T 11-11-2016 AUP74_RS09840 9e38dc272178f7cf7e3cda70cb086951 307 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 5 115 1.9E-18 T 11-11-2016 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AUP74_RS09840 9e38dc272178f7cf7e3cda70cb086951 307 Gene3D G3DSA:3.40.50.2020 4 157 8.2E-28 T 11-11-2016 IPR029057 Phosphoribosyltransferase-like AUP74_RS09840 9e38dc272178f7cf7e3cda70cb086951 307 SUPERFAMILY SSF53271 7 157 5.82E-36 T 11-11-2016 IPR029057 Phosphoribosyltransferase-like AUP74_RS09840 9e38dc272178f7cf7e3cda70cb086951 307 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 7 295 3.1E-52 T 11-11-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AUP74_RS09840 9e38dc272178f7cf7e3cda70cb086951 307 Gene3D G3DSA:3.40.50.2020 158 274 9.0E-19 T 11-11-2016 IPR029057 Phosphoribosyltransferase-like AUP74_RS09840 9e38dc272178f7cf7e3cda70cb086951 307 Pfam PF00156 Phosphoribosyl transferase domain 137 266 4.5E-11 T 11-11-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 AUP74_RS09840 9e38dc272178f7cf7e3cda70cb086951 307 SUPERFAMILY SSF53271 85 274 6.42E-27 T 11-11-2016 IPR029057 Phosphoribosyltransferase-like AUP74_RS09840 9e38dc272178f7cf7e3cda70cb086951 307 SMART SM01400 3 118 1.1E-31 T 11-11-2016 AUP74_RS15550 228f85d4d8f915c3a5977e8e706845e3 116 Pfam PF01245 Ribosomal protein L19 5 114 9.6E-51 T 11-11-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS15550 228f85d4d8f915c3a5977e8e706845e3 116 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 3 115 31.157 T 11-11-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS15550 228f85d4d8f915c3a5977e8e706845e3 116 ProSitePatterns PS01015 Ribosomal protein L19 signature. 87 102 - T 11-11-2016 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS15550 228f85d4d8f915c3a5977e8e706845e3 116 PIRSF PIRSF002191 1 116 2.4E-50 T 11-11-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS15550 228f85d4d8f915c3a5977e8e706845e3 116 SUPERFAMILY SSF50104 2 115 1.7E-47 T 11-11-2016 IPR008991 Translation protein SH3-like domain AUP74_RS15550 228f85d4d8f915c3a5977e8e706845e3 116 PRINTS PR00061 Ribosomal protein L19 signature 89 114 6.5E-42 T 11-11-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS15550 228f85d4d8f915c3a5977e8e706845e3 116 PRINTS PR00061 Ribosomal protein L19 signature 35 64 6.5E-42 T 11-11-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS15550 228f85d4d8f915c3a5977e8e706845e3 116 PRINTS PR00061 Ribosomal protein L19 signature 5 34 6.5E-42 T 11-11-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS15550 228f85d4d8f915c3a5977e8e706845e3 116 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 4 114 1.2E-50 T 11-11-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS04715 a0f6006422bdcf0fc4ce5851539e6f30 216 SUPERFAMILY SSF52833 82 211 7.96E-8 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS04715 a0f6006422bdcf0fc4ce5851539e6f30 216 Gene3D G3DSA:3.40.30.10 82 211 2.3E-6 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS05420 d156bac3a5d57da33678da78428306bc 419 Pfam PF00909 Ammonium Transporter Family 17 413 4.2E-95 T 11-11-2016 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 AUP74_RS05420 d156bac3a5d57da33678da78428306bc 419 SUPERFAMILY SSF111352 10 394 5.23E-100 T 11-11-2016 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 AUP74_RS05420 d156bac3a5d57da33678da78428306bc 419 Gene3D G3DSA:1.10.3430.10 9 394 7.9E-105 T 11-11-2016 IPR029020 Ammonium/urea transporter AUP74_RS05420 d156bac3a5d57da33678da78428306bc 419 ProSitePatterns PS01219 Ammonium transporters signature. 174 199 - T 11-11-2016 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 AUP74_RS05420 d156bac3a5d57da33678da78428306bc 419 TIGRFAM TIGR03644 marine_trans_1: probable ammonium transporter, marine subtype 10 416 1.5E-205 T 11-11-2016 IPR019879 Ammonium transporter, marine subtype AUP74_RS13000 b86b439f73ef50e2113edf1f925c6829 148 Pfam PF12833 Helix-turn-helix domain 66 143 8.2E-18 T 11-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AUP74_RS13000 b86b439f73ef50e2113edf1f925c6829 148 SMART SM00342 59 141 1.3E-14 T 11-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AUP74_RS13000 b86b439f73ef50e2113edf1f925c6829 148 SUPERFAMILY SSF46689 94 145 6.15E-12 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS13000 b86b439f73ef50e2113edf1f925c6829 148 Gene3D G3DSA:1.10.10.60 94 144 3.9E-13 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS13900 e18e6c5eee2d567d467fa83d72354900 545 SMART SM00388 164 229 6.4E-6 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS13900 e18e6c5eee2d567d467fa83d72354900 545 SUPERFAMILY SSF55874 219 391 3.01E-37 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS13900 e18e6c5eee2d567d467fa83d72354900 545 Gene3D G3DSA:3.30.565.10 229 391 4.4E-36 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS13900 e18e6c5eee2d567d467fa83d72354900 545 Pfam PF00989 PAS fold 31 146 1.1E-10 T 11-11-2016 IPR013767 PAS fold GO:0006355 AUP74_RS13900 e18e6c5eee2d567d467fa83d72354900 545 Gene3D G3DSA:3.40.50.2300 412 532 1.5E-29 T 11-11-2016 AUP74_RS13900 e18e6c5eee2d567d467fa83d72354900 545 SMART SM00448 412 525 7.6E-18 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS13900 e18e6c5eee2d567d467fa83d72354900 545 Gene3D G3DSA:1.10.287.130 157 225 1.8E-6 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS13900 e18e6c5eee2d567d467fa83d72354900 545 SMART SM00387 270 393 1.6E-23 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS13900 e18e6c5eee2d567d467fa83d72354900 545 SMART SM00091 31 96 1.5E-10 T 11-11-2016 IPR000014 PAS domain AUP74_RS13900 e18e6c5eee2d567d467fa83d72354900 545 Pfam PF00072 Response regulator receiver domain 414 524 3.5E-21 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS13900 e18e6c5eee2d567d467fa83d72354900 545 SMART SM00086 107 149 1.1E-4 T 11-11-2016 IPR001610 PAC motif AUP74_RS13900 e18e6c5eee2d567d467fa83d72354900 545 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 270 391 1.6E-15 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS13900 e18e6c5eee2d567d467fa83d72354900 545 Gene3D G3DSA:3.30.450.20 20 147 5.1E-22 T 11-11-2016 AUP74_RS13900 e18e6c5eee2d567d467fa83d72354900 545 PRINTS PR00344 Bacterial sensor protein C-terminal signature 322 336 1.3E-16 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS13900 e18e6c5eee2d567d467fa83d72354900 545 PRINTS PR00344 Bacterial sensor protein C-terminal signature 340 350 1.3E-16 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS13900 e18e6c5eee2d567d467fa83d72354900 545 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 371 1.3E-16 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS13900 e18e6c5eee2d567d467fa83d72354900 545 PRINTS PR00344 Bacterial sensor protein C-terminal signature 377 390 1.3E-16 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS13900 e18e6c5eee2d567d467fa83d72354900 545 Pfam PF00512 His Kinase A (phospho-acceptor) domain 166 227 3.2E-8 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS13900 e18e6c5eee2d567d467fa83d72354900 545 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 27 156 1.2E-21 T 11-11-2016 IPR000014 PAS domain AUP74_RS13900 e18e6c5eee2d567d467fa83d72354900 545 SUPERFAMILY SSF55785 18 147 7.85E-22 T 11-11-2016 IPR000014 PAS domain AUP74_RS13900 e18e6c5eee2d567d467fa83d72354900 545 SUPERFAMILY SSF47384 157 227 2.75E-11 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS13900 e18e6c5eee2d567d467fa83d72354900 545 SUPERFAMILY SSF52172 410 531 7.26E-30 T 11-11-2016 IPR011006 CheY-like superfamily AUP74_RS04060 a879b2d03bf82f1fe4d2e3145b49a482 1038 SUPERFAMILY SSF82693 277 333 4.71E-19 T 11-11-2016 AUP74_RS04060 a879b2d03bf82f1fe4d2e3145b49a482 1038 SUPERFAMILY SSF82693 154 191 4.71E-19 T 11-11-2016 AUP74_RS04060 a879b2d03bf82f1fe4d2e3145b49a482 1038 Gene3D G3DSA:1.10.3850.10 283 509 3.6E-52 T 11-11-2016 AUP74_RS04060 a879b2d03bf82f1fe4d2e3145b49a482 1038 Gene3D G3DSA:1.10.3850.10 816 1031 1.9E-57 T 11-11-2016 AUP74_RS04060 a879b2d03bf82f1fe4d2e3145b49a482 1038 SUPERFAMILY SSF82714 192 275 9.94E-19 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS04060 a879b2d03bf82f1fe4d2e3145b49a482 1038 Gene3D G3DSA:3.30.2090.10 725 813 1.6E-13 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS04060 a879b2d03bf82f1fe4d2e3145b49a482 1038 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 1.2E-20 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS04060 a879b2d03bf82f1fe4d2e3145b49a482 1038 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 1.2E-20 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS04060 a879b2d03bf82f1fe4d2e3145b49a482 1038 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 1.2E-20 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS04060 a879b2d03bf82f1fe4d2e3145b49a482 1038 PRINTS PR00702 Acriflavin resistance protein family signature 339 362 1.2E-20 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS04060 a879b2d03bf82f1fe4d2e3145b49a482 1038 PRINTS PR00702 Acriflavin resistance protein family signature 480 503 1.2E-20 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS04060 a879b2d03bf82f1fe4d2e3145b49a482 1038 PRINTS PR00702 Acriflavin resistance protein family signature 366 387 1.2E-20 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS04060 a879b2d03bf82f1fe4d2e3145b49a482 1038 SUPERFAMILY SSF82693 579 667 6.8E-6 T 11-11-2016 AUP74_RS04060 a879b2d03bf82f1fe4d2e3145b49a482 1038 SUPERFAMILY SSF82693 42 127 3.4E-21 T 11-11-2016 AUP74_RS04060 a879b2d03bf82f1fe4d2e3145b49a482 1038 SUPERFAMILY SSF82866 299 508 1.83E-36 T 11-11-2016 AUP74_RS04060 a879b2d03bf82f1fe4d2e3145b49a482 1038 Gene3D G3DSA:3.30.2090.10 192 274 5.9E-20 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS04060 a879b2d03bf82f1fe4d2e3145b49a482 1038 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1036 0.0 T 11-11-2016 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 AUP74_RS04060 a879b2d03bf82f1fe4d2e3145b49a482 1038 Gene3D G3DSA:3.30.70.1430 42 143 4.2E-28 T 11-11-2016 AUP74_RS04060 a879b2d03bf82f1fe4d2e3145b49a482 1038 Pfam PF00873 AcrB/AcrD/AcrF family 5 1031 0.0 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS04060 a879b2d03bf82f1fe4d2e3145b49a482 1038 SUPERFAMILY SSF82714 725 809 1.7E-15 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS04060 a879b2d03bf82f1fe4d2e3145b49a482 1038 SUPERFAMILY SSF82866 809 1033 9.81E-55 T 11-11-2016 AUP74_RS10995 3d97f1e442f0f096e2cabc263da48b19 350 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 314 329 2.3E-5 T 11-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AUP74_RS10995 3d97f1e442f0f096e2cabc263da48b19 350 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 329 345 2.3E-5 T 11-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AUP74_RS10995 3d97f1e442f0f096e2cabc263da48b19 350 SUPERFAMILY SSF46689 298 347 1.66E-13 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS10995 3d97f1e442f0f096e2cabc263da48b19 350 Pfam PF12833 Helix-turn-helix domain 269 347 2.8E-19 T 11-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AUP74_RS10995 3d97f1e442f0f096e2cabc263da48b19 350 Gene3D G3DSA:1.10.10.60 298 347 3.5E-16 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS10995 3d97f1e442f0f096e2cabc263da48b19 350 SMART SM00342 263 345 3.4E-19 T 11-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AUP74_RS10995 3d97f1e442f0f096e2cabc263da48b19 350 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 26 219 3.0E-26 T 11-11-2016 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal AUP74_RS02015 a659e091eefcbb1b4d192936ecc0c983 220 SMART SM00862 145 216 5.3E-29 T 11-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AUP74_RS02015 a659e091eefcbb1b4d192936ecc0c983 220 Gene3D G3DSA:1.10.10.10 123 217 7.5E-30 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS02015 a659e091eefcbb1b4d192936ecc0c983 220 SMART SM00448 1 112 3.2E-38 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS02015 a659e091eefcbb1b4d192936ecc0c983 220 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 7.1E-24 T 11-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AUP74_RS02015 a659e091eefcbb1b4d192936ecc0c983 220 SUPERFAMILY SSF52172 2 178 1.18E-37 T 11-11-2016 IPR011006 CheY-like superfamily AUP74_RS02015 a659e091eefcbb1b4d192936ecc0c983 220 Gene3D G3DSA:3.40.50.2300 2 120 6.8E-37 T 11-11-2016 AUP74_RS02015 a659e091eefcbb1b4d192936ecc0c983 220 Pfam PF00072 Response regulator receiver domain 3 112 4.3E-28 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS03785 db7f360bf7a963e45fe167f20789d7df 292 SUPERFAMILY SSF56112 10 264 1.2E-32 T 11-11-2016 IPR011009 Protein kinase-like domain AUP74_RS03785 db7f360bf7a963e45fe167f20789d7df 292 Gene3D G3DSA:3.90.1200.10 78 264 2.6E-19 T 11-11-2016 AUP74_RS03785 db7f360bf7a963e45fe167f20789d7df 292 Pfam PF01636 Phosphotransferase enzyme family 24 244 6.1E-23 T 11-11-2016 IPR002575 Aminoglycoside phosphotransferase AUP74_RS05840 8ed8736f0377835e87fa7b613760b3da 383 Pfam PF12221 Bacterial membrane protein N terminal 1 46 1.3E-17 T 11-11-2016 IPR020980 Menbrane protein HflK, N-terminal AUP74_RS05840 8ed8736f0377835e87fa7b613760b3da 383 SUPERFAMILY SSF117892 106 238 2.48E-20 T 11-11-2016 IPR001107 Band 7 domain AUP74_RS05840 8ed8736f0377835e87fa7b613760b3da 383 SMART SM00244 74 234 1.4E-32 T 11-11-2016 IPR001107 Band 7 domain AUP74_RS05840 8ed8736f0377835e87fa7b613760b3da 383 TIGRFAM TIGR01933 hflK: HflK protein 76 336 2.4E-97 T 11-11-2016 IPR010201 HflK GO:0016021 AUP74_RS05840 8ed8736f0377835e87fa7b613760b3da 383 Pfam PF01145 SPFH domain / Band 7 family 78 249 1.0E-25 T 11-11-2016 IPR001107 Band 7 domain AUP74_RS06945 d30f56c912ca27aae33dacfd38adcd8d 206 Gene3D G3DSA:3.10.290.10 99 198 6.8E-32 T 11-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 AUP74_RS06945 d30f56c912ca27aae33dacfd38adcd8d 206 SMART SM00363 96 160 3.7E-17 T 11-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 AUP74_RS06945 d30f56c912ca27aae33dacfd38adcd8d 206 ProSitePatterns PS00632 Ribosomal protein S4 signature. 94 118 - T 11-11-2016 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06945 d30f56c912ca27aae33dacfd38adcd8d 206 Pfam PF01479 S4 domain 97 143 1.0E-18 T 11-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 AUP74_RS06945 d30f56c912ca27aae33dacfd38adcd8d 206 SMART SM01390 3 95 4.0E-50 T 11-11-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 AUP74_RS06945 d30f56c912ca27aae33dacfd38adcd8d 206 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 206 35.798 T 11-11-2016 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 AUP74_RS06945 d30f56c912ca27aae33dacfd38adcd8d 206 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 206 1.4E-81 T 11-11-2016 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 AUP74_RS06945 d30f56c912ca27aae33dacfd38adcd8d 206 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 95 5.7E-32 T 11-11-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 AUP74_RS06945 d30f56c912ca27aae33dacfd38adcd8d 206 SUPERFAMILY SSF55174 3 206 2.75E-69 T 11-11-2016 AUP74_RS06945 d30f56c912ca27aae33dacfd38adcd8d 206 Gene3D G3DSA:1.10.1050.10 1 98 9.6E-42 T 11-11-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 AUP74_RS05040 93de951cf94c76ef626d4fb77aff8247 498 SUPERFAMILY SSF52402 196 338 1.57E-8 T 11-11-2016 AUP74_RS05040 93de951cf94c76ef626d4fb77aff8247 498 Gene3D G3DSA:3.40.50.620 198 326 6.7E-7 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS15960 c879b4b0b501eecd9fbe695f12269275 175 Pfam PF05433 Glycine zipper 2TM domain 72 113 1.1E-6 T 11-11-2016 IPR008816 Glycine zipper 2TM domain GO:0019867 AUP74_RS07855 de5be75c9ea5d701f217ed81755b2db5 158 Pfam PF01037 Lrp/AsnC ligand binding domain 68 142 1.4E-14 T 11-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AUP74_RS07855 de5be75c9ea5d701f217ed81755b2db5 158 SUPERFAMILY SSF46785 2 60 5.17E-13 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS07855 de5be75c9ea5d701f217ed81755b2db5 158 Gene3D G3DSA:3.30.70.920 64 139 9.0E-19 T 11-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AUP74_RS07855 de5be75c9ea5d701f217ed81755b2db5 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 6.1E-12 T 11-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 AUP74_RS07855 de5be75c9ea5d701f217ed81755b2db5 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 6.1E-12 T 11-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 AUP74_RS07855 de5be75c9ea5d701f217ed81755b2db5 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 6.1E-12 T 11-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 AUP74_RS07855 de5be75c9ea5d701f217ed81755b2db5 158 SMART SM00344 3 111 1.7E-27 T 11-11-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AUP74_RS07855 de5be75c9ea5d701f217ed81755b2db5 158 SUPERFAMILY SSF54909 67 145 1.01E-12 T 11-11-2016 IPR011008 Dimeric alpha-beta barrel AUP74_RS07855 de5be75c9ea5d701f217ed81755b2db5 158 Gene3D G3DSA:1.10.10.10 4 54 1.2E-17 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS07855 de5be75c9ea5d701f217ed81755b2db5 158 Pfam PF13404 AsnC-type helix-turn-helix domain 3 43 1.2E-14 T 11-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 AUP74_RS07570 c3ef3d26636ffd2e4a138bcd711641c6 307 Pfam PF00892 EamA-like transporter family 33 161 7.5E-7 T 11-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 AUP74_RS07570 c3ef3d26636ffd2e4a138bcd711641c6 307 Pfam PF00892 EamA-like transporter family 172 301 5.4E-12 T 11-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 AUP74_RS07570 c3ef3d26636ffd2e4a138bcd711641c6 307 SUPERFAMILY SSF103481 211 305 6.67E-12 T 11-11-2016 AUP74_RS07570 c3ef3d26636ffd2e4a138bcd711641c6 307 SUPERFAMILY SSF103481 68 164 3.14E-5 T 11-11-2016 AUP74_RS10020 b967f8f66a4037d55003a42da44a7f3e 165 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 3 71 3.7E-7 T 11-11-2016 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 AUP74_RS10020 b967f8f66a4037d55003a42da44a7f3e 165 SUPERFAMILY SSF53155 2 80 2.35E-14 T 11-11-2016 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 AUP74_RS10020 b967f8f66a4037d55003a42da44a7f3e 165 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 75 154 1.9E-35 T 11-11-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 AUP74_RS10020 b967f8f66a4037d55003a42da44a7f3e 165 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 1 157 37.326 T 11-11-2016 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 AUP74_RS10020 b967f8f66a4037d55003a42da44a7f3e 165 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 76 155 8.2E-32 T 11-11-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 AUP74_RS10020 b967f8f66a4037d55003a42da44a7f3e 165 Gene3D G3DSA:1.10.10.10 74 160 3.4E-35 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS10020 b967f8f66a4037d55003a42da44a7f3e 165 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 125 131 - T 11-11-2016 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 AUP74_RS10020 b967f8f66a4037d55003a42da44a7f3e 165 SUPERFAMILY SSF46767 74 156 5.76E-32 T 11-11-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 AUP74_RS11530 a6d592d32b07bb635517375822b93bdd 312 SMART SM00046 11 134 3.0E-8 T 11-11-2016 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 AUP74_RS11530 a6d592d32b07bb635517375822b93bdd 312 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 12 297 1.9E-53 T 11-11-2016 IPR005218 Diacylglycerol/lipid kinase AUP74_RS11530 a6d592d32b07bb635517375822b93bdd 312 SUPERFAMILY SSF111331 11 298 2.62E-70 T 11-11-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain AUP74_RS11530 a6d592d32b07bb635517375822b93bdd 312 Gene3D G3DSA:3.40.50.10330 22 102 1.0E-4 T 11-11-2016 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 AUP74_RS11530 a6d592d32b07bb635517375822b93bdd 312 Pfam PF00781 Diacylglycerol kinase catalytic domain 11 131 1.3E-24 T 11-11-2016 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 AUP74_RS12660 521d7eb0affd7029102344740e5a943d 587 Gene3D G3DSA:3.40.50.980 225 387 8.0E-34 T 11-11-2016 AUP74_RS12660 521d7eb0affd7029102344740e5a943d 587 Pfam PF00501 AMP-binding enzyme 56 475 1.4E-89 T 11-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 AUP74_RS12660 521d7eb0affd7029102344740e5a943d 587 SUPERFAMILY SSF56801 45 575 1.31E-154 T 11-11-2016 AUP74_RS12660 521d7eb0affd7029102344740e5a943d 587 Gene3D G3DSA:3.30.300.30 470 571 2.3E-28 T 11-11-2016 AUP74_RS12660 521d7eb0affd7029102344740e5a943d 587 Pfam PF13193 AMP-binding enzyme C-terminal domain 484 562 4.2E-24 T 11-11-2016 IPR025110 AMP-binding enzyme C-terminal domain AUP74_RS12660 521d7eb0affd7029102344740e5a943d 587 ProSitePatterns PS00455 Putative AMP-binding domain signature. 220 231 - T 11-11-2016 IPR020845 AMP-binding, conserved site AUP74_RS12660 521d7eb0affd7029102344740e5a943d 587 Gene3D G3DSA:2.30.38.10 388 469 1.4E-20 T 11-11-2016 AUP74_RS12660 521d7eb0affd7029102344740e5a943d 587 Gene3D G3DSA:3.40.50.980 52 224 9.8E-33 T 11-11-2016 AUP74_RS00265 ae8728fe79c1a29a3661ba4e1e7a5285 236 SUPERFAMILY SSF100950 2 230 1.81E-51 T 11-11-2016 AUP74_RS00265 ae8728fe79c1a29a3661ba4e1e7a5285 236 Gene3D G3DSA:3.40.50.1360 5 233 1.9E-50 T 11-11-2016 AUP74_RS00265 ae8728fe79c1a29a3661ba4e1e7a5285 236 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 7 228 1.2E-51 T 11-11-2016 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 AUP74_RS00265 ae8728fe79c1a29a3661ba4e1e7a5285 236 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 9 225 4.7E-51 T 11-11-2016 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 AUP74_RS05235 38cc5aa4bc4f492f92800d6ac9bc8187 327 SUPERFAMILY SSF53335 2 316 3.82E-57 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS05235 38cc5aa4bc4f492f92800d6ac9bc8187 327 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 3 19 7.7E-7 T 11-11-2016 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 AUP74_RS05235 38cc5aa4bc4f492f92800d6ac9bc8187 327 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 150 163 7.7E-7 T 11-11-2016 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 AUP74_RS05235 38cc5aa4bc4f492f92800d6ac9bc8187 327 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 107 121 7.7E-7 T 11-11-2016 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 AUP74_RS05235 38cc5aa4bc4f492f92800d6ac9bc8187 327 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 4 315 2.5E-29 T 11-11-2016 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 AUP74_RS05235 38cc5aa4bc4f492f92800d6ac9bc8187 327 Gene3D G3DSA:3.90.120.10 160 304 6.8E-10 T 11-11-2016 AUP74_RS05235 38cc5aa4bc4f492f92800d6ac9bc8187 327 Pfam PF00145 C-5 cytosine-specific DNA methylase 2 316 2.1E-32 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS05235 38cc5aa4bc4f492f92800d6ac9bc8187 327 Gene3D G3DSA:3.40.50.150 1 159 2.5E-37 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS06360 5abf704104ee0a5308f7367814a6b7d9 240 SMART SM00448 15 127 4.4E-41 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS06360 5abf704104ee0a5308f7367814a6b7d9 240 Gene3D G3DSA:1.10.10.10 139 236 1.4E-18 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS06360 5abf704104ee0a5308f7367814a6b7d9 240 SMART SM00862 160 234 3.8E-14 T 11-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AUP74_RS06360 5abf704104ee0a5308f7367814a6b7d9 240 Pfam PF00486 Transcriptional regulatory protein, C terminal 160 234 1.1E-13 T 11-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AUP74_RS06360 5abf704104ee0a5308f7367814a6b7d9 240 SUPERFAMILY SSF46894 143 235 2.89E-13 T 11-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AUP74_RS06360 5abf704104ee0a5308f7367814a6b7d9 240 SUPERFAMILY SSF52172 13 176 4.41E-41 T 11-11-2016 IPR011006 CheY-like superfamily AUP74_RS06360 5abf704104ee0a5308f7367814a6b7d9 240 Pfam PF00072 Response regulator receiver domain 17 125 1.8E-25 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS06360 5abf704104ee0a5308f7367814a6b7d9 240 Gene3D G3DSA:3.40.50.2300 9 138 7.4E-39 T 11-11-2016 AUP74_RS15265 7b4b33610ebf6c86f9fbb89ce85627cc 514 Pfam PF03806 AbgT putative transporter family 16 513 1.5E-199 T 11-11-2016 IPR004697 p-aminobenzoyl-glutamate transport protein AbgT GO:0015558|GO:1902604 AUP74_RS02855 80a188bdce0f1f9d66c83c3f14045562 178 Pfam PF00710 Asparaginase, N-terminal 10 167 2.6E-30 T 11-11-2016 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 AUP74_RS02855 80a188bdce0f1f9d66c83c3f14045562 178 Gene3D G3DSA:3.40.50.1170 6 173 2.4E-34 T 11-11-2016 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 AUP74_RS02855 80a188bdce0f1f9d66c83c3f14045562 178 PIRSF PIRSF001220 4 177 5.4E-26 T 11-11-2016 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 AUP74_RS02855 80a188bdce0f1f9d66c83c3f14045562 178 PIRSF PIRSF500176 6 175 5.1E-28 T 11-11-2016 AUP74_RS02855 80a188bdce0f1f9d66c83c3f14045562 178 SUPERFAMILY SSF53774 8 172 1.7E-35 T 11-11-2016 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 AUP74_RS02855 80a188bdce0f1f9d66c83c3f14045562 178 SMART SM00870 9 177 0.0038 T 11-11-2016 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 AUP74_RS02855 80a188bdce0f1f9d66c83c3f14045562 178 PRINTS PR00139 Asparaginase/glutaminase family signature 10 21 1.6E-7 T 11-11-2016 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 AUP74_RS02855 80a188bdce0f1f9d66c83c3f14045562 178 PRINTS PR00139 Asparaginase/glutaminase family signature 85 103 1.6E-7 T 11-11-2016 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 AUP74_RS03005 e4b03431c23102b76392e173bec310c8 199 PRINTS PR01021 OMPA domain signature 98 113 8.1E-7 T 11-11-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AUP74_RS03005 e4b03431c23102b76392e173bec310c8 199 PRINTS PR01021 OMPA domain signature 113 129 8.1E-7 T 11-11-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AUP74_RS03005 e4b03431c23102b76392e173bec310c8 199 Gene3D G3DSA:3.30.1330.60 60 168 2.3E-30 T 11-11-2016 IPR006665 OmpA-like domain AUP74_RS03005 e4b03431c23102b76392e173bec310c8 199 Pfam PF00691 OmpA family 68 162 7.0E-18 T 11-11-2016 IPR006665 OmpA-like domain AUP74_RS03005 e4b03431c23102b76392e173bec310c8 199 SUPERFAMILY SSF103088 60 167 6.54E-29 T 11-11-2016 IPR006665 OmpA-like domain AUP74_RS03005 e4b03431c23102b76392e173bec310c8 199 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 113 130 1.9E-9 T 11-11-2016 AUP74_RS03005 e4b03431c23102b76392e173bec310c8 199 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 151 171 1.9E-9 T 11-11-2016 AUP74_RS03005 e4b03431c23102b76392e173bec310c8 199 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 131 150 1.9E-9 T 11-11-2016 AUP74_RS15315 ab88ecb18ba18e9cda37447358670a51 336 ProSitePatterns PS00534 Ferrochelatase signature. 197 216 - T 11-11-2016 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 AUP74_RS15315 ab88ecb18ba18e9cda37447358670a51 336 SUPERFAMILY SSF53800 2 328 1.57E-102 T 11-11-2016 AUP74_RS15315 ab88ecb18ba18e9cda37447358670a51 336 TIGRFAM TIGR00109 hemH: ferrochelatase 3 328 1.6E-94 T 11-11-2016 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 AUP74_RS15315 ab88ecb18ba18e9cda37447358670a51 336 Gene3D G3DSA:3.40.50.1400 2 208 3.4E-67 T 11-11-2016 AUP74_RS15315 ab88ecb18ba18e9cda37447358670a51 336 Hamap MF_00323 Ferrochelatase [hemH]. 1 328 36.764 T 11-11-2016 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 AUP74_RS15315 ab88ecb18ba18e9cda37447358670a51 336 Pfam PF00762 Ferrochelatase 3 327 2.3E-108 T 11-11-2016 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 AUP74_RS15315 ab88ecb18ba18e9cda37447358670a51 336 Gene3D G3DSA:3.40.50.1400 209 328 7.3E-35 T 11-11-2016 AUP74_RS04480 914ca824af256ef6fd9d9c4b96129b30 373 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 2 337 1.5E-87 T 11-11-2016 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 AUP74_RS04480 914ca824af256ef6fd9d9c4b96129b30 373 ProSitePatterns PS00618 RecF protein signature 2. 296 314 - T 11-11-2016 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 AUP74_RS04480 914ca824af256ef6fd9d9c4b96129b30 373 Pfam PF02463 RecF/RecN/SMC N terminal domain 1 333 1.1E-21 T 11-11-2016 IPR003395 RecF/RecN/SMC, N-terminal AUP74_RS04480 914ca824af256ef6fd9d9c4b96129b30 373 SUPERFAMILY SSF52540 1 328 1.23E-26 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04480 914ca824af256ef6fd9d9c4b96129b30 373 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 373 80.457 T 11-11-2016 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 AUP74_RS04480 914ca824af256ef6fd9d9c4b96129b30 373 Gene3D G3DSA:3.40.50.300 1 163 6.1E-29 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04480 914ca824af256ef6fd9d9c4b96129b30 373 Gene3D G3DSA:3.40.50.300 229 328 6.1E-29 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS08715 6f9f6361d74541bc16a57817393a7044 301 Gene3D G3DSA:3.40.50.720 1 194 6.8E-29 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS08715 6f9f6361d74541bc16a57817393a7044 301 SUPERFAMILY SSF51735 1 292 2.99E-98 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS08715 6f9f6361d74541bc16a57817393a7044 301 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 289 1.2E-100 T 11-11-2016 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581 AUP74_RS08715 6f9f6361d74541bc16a57817393a7044 301 Gene3D G3DSA:3.90.25.10 219 281 2.2E-33 T 11-11-2016 AUP74_RS08715 6f9f6361d74541bc16a57817393a7044 301 Pfam PF04321 RmlD substrate binding domain 1 291 7.8E-108 T 11-11-2016 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581 AUP74_RS06385 dc57182669af8fbd6dd03ccad4e4b751 425 Hamap MF_01232 UPF0229 protein YeaH [yeaH]. 1 424 38.466 T 11-11-2016 IPR006698 Uncharacterised protein family UPF0229 AUP74_RS06385 dc57182669af8fbd6dd03ccad4e4b751 425 Pfam PF04285 Protein of unknown function (DUF444) 4 421 1.4E-176 T 11-11-2016 IPR006698 Uncharacterised protein family UPF0229 AUP74_RS04475 e943e086e04deeb49bd9ae5145fa4b02 368 SUPERFAMILY SSF55979 126 246 3.66E-28 T 11-11-2016 AUP74_RS04475 e943e086e04deeb49bd9ae5145fa4b02 368 Gene3D G3DSA:3.10.150.10 1 119 1.0E-32 T 11-11-2016 AUP74_RS04475 e943e086e04deeb49bd9ae5145fa4b02 368 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 248 367 8.4E-39 T 11-11-2016 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS04475 e943e086e04deeb49bd9ae5145fa4b02 368 Pfam PF02767 DNA polymerase III beta subunit, central domain 130 245 2.0E-32 T 11-11-2016 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS04475 e943e086e04deeb49bd9ae5145fa4b02 368 PIRSF PIRSF000804 1 368 7.1E-121 T 11-11-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS04475 e943e086e04deeb49bd9ae5145fa4b02 368 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 368 7.4E-104 T 11-11-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS04475 e943e086e04deeb49bd9ae5145fa4b02 368 Gene3D G3DSA:3.10.150.10 251 368 5.3E-39 T 11-11-2016 AUP74_RS04475 e943e086e04deeb49bd9ae5145fa4b02 368 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 118 1.7E-36 T 11-11-2016 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS04475 e943e086e04deeb49bd9ae5145fa4b02 368 Gene3D G3DSA:3.10.150.10 125 250 2.2E-36 T 11-11-2016 AUP74_RS04475 e943e086e04deeb49bd9ae5145fa4b02 368 SUPERFAMILY SSF55979 247 368 1.81E-36 T 11-11-2016 AUP74_RS04475 e943e086e04deeb49bd9ae5145fa4b02 368 SUPERFAMILY SSF55979 1 118 1.88E-29 T 11-11-2016 AUP74_RS04475 e943e086e04deeb49bd9ae5145fa4b02 368 SMART SM00480 17 364 3.8E-136 T 11-11-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS08950 dfdeb3ece13d50380fca3d24c4408cf0 278 PIRSF PIRSF036480 1 278 5.8E-113 T 11-11-2016 AUP74_RS08950 dfdeb3ece13d50380fca3d24c4408cf0 278 Gene3D G3DSA:3.30.70.260 2 71 3.0E-11 T 11-11-2016 AUP74_RS08950 dfdeb3ece13d50380fca3d24c4408cf0 278 Pfam PF01842 ACT domain 5 64 8.4E-8 T 11-11-2016 IPR002912 ACT domain GO:0008152|GO:0016597 AUP74_RS08950 dfdeb3ece13d50380fca3d24c4408cf0 278 SUPERFAMILY SSF55021 4 64 8.74E-8 T 11-11-2016 AUP74_RS08950 dfdeb3ece13d50380fca3d24c4408cf0 278 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 1 277 46.368 T 11-11-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 AUP74_RS08950 dfdeb3ece13d50380fca3d24c4408cf0 278 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 6 32 1.9E-64 T 11-11-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 AUP74_RS08950 dfdeb3ece13d50380fca3d24c4408cf0 278 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 251 276 1.9E-64 T 11-11-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 AUP74_RS08950 dfdeb3ece13d50380fca3d24c4408cf0 278 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 105 132 1.9E-64 T 11-11-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 AUP74_RS08950 dfdeb3ece13d50380fca3d24c4408cf0 278 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 38 50 1.9E-64 T 11-11-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 AUP74_RS08950 dfdeb3ece13d50380fca3d24c4408cf0 278 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 83 105 1.9E-64 T 11-11-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 AUP74_RS08950 dfdeb3ece13d50380fca3d24c4408cf0 278 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 229 251 1.9E-64 T 11-11-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 AUP74_RS08950 dfdeb3ece13d50380fca3d24c4408cf0 278 Gene3D G3DSA:3.40.50.170 81 274 1.8E-56 T 11-11-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AUP74_RS08950 dfdeb3ece13d50380fca3d24c4408cf0 278 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 4 277 6.5E-122 T 11-11-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 AUP74_RS08950 dfdeb3ece13d50380fca3d24c4408cf0 278 SUPERFAMILY SSF53328 82 278 3.01E-59 T 11-11-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AUP74_RS08950 dfdeb3ece13d50380fca3d24c4408cf0 278 Pfam PF00551 Formyl transferase 82 259 7.5E-47 T 11-11-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AUP74_RS16665 06db89f443259bf0f4b580a4ae8d9499 570 SUPERFAMILY SSF160246 3 142 3.14E-32 T 11-11-2016 AUP74_RS16665 06db89f443259bf0f4b580a4ae8d9499 570 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 387 401 - T 11-11-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 AUP74_RS16665 06db89f443259bf0f4b580a4ae8d9499 570 Gene3D G3DSA:3.30.450.90 168 292 8.1E-52 T 11-11-2016 AUP74_RS16665 06db89f443259bf0f4b580a4ae8d9499 570 TIGRFAM TIGR02538 type_IV_pilB: type IV-A pilus assembly ATPase PilB 8 570 4.8E-258 T 11-11-2016 IPR013374 ATPase, type IV, pilus assembly, PilB GO:0005524|GO:0008565|GO:0009297 AUP74_RS16665 06db89f443259bf0f4b580a4ae8d9499 570 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 43 145 6.5E-14 T 11-11-2016 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 AUP74_RS16665 06db89f443259bf0f4b580a4ae8d9499 570 SUPERFAMILY SSF52540 182 568 5.63E-96 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS16665 06db89f443259bf0f4b580a4ae8d9499 570 Pfam PF00437 Type II/IV secretion system protein 193 459 1.7E-89 T 11-11-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 AUP74_RS16665 06db89f443259bf0f4b580a4ae8d9499 570 Gene3D G3DSA:3.40.50.300 299 568 2.4E-98 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS12740 16c6588d21ba8849819083b78eae9fb1 332 Pfam PF00561 alpha/beta hydrolase fold 60 300 1.2E-15 T 11-11-2016 IPR000073 Alpha/beta hydrolase fold-1 AUP74_RS12740 16c6588d21ba8849819083b78eae9fb1 332 ProSitePatterns PS01133 Uncharacterized protein family UPF0017 signature. 227 268 - T 11-11-2016 IPR000952 AB hydrolase 4, conserved site AUP74_RS12740 16c6588d21ba8849819083b78eae9fb1 332 SUPERFAMILY SSF53474 30 300 2.04E-38 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS12740 16c6588d21ba8849819083b78eae9fb1 332 Gene3D G3DSA:3.40.50.1820 248 303 9.3E-27 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS12740 16c6588d21ba8849819083b78eae9fb1 332 Gene3D G3DSA:3.40.50.1820 42 171 9.3E-27 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS12740 16c6588d21ba8849819083b78eae9fb1 332 PIRSF PIRSF005211 1 332 1.9E-105 T 11-11-2016 IPR012020 AB hydrolase 4 family AUP74_RS02300 7a6dd6008477ffc158ded267006c332b 611 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 609 8.3E-250 T 11-11-2016 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AUP74_RS02300 7a6dd6008477ffc158ded267006c332b 611 SUPERFAMILY SSF143975 4 418 5.49E-132 T 11-11-2016 AUP74_RS02300 7a6dd6008477ffc158ded267006c332b 611 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 11-11-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AUP74_RS02300 7a6dd6008477ffc158ded267006c332b 611 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 609 44.794 T 11-11-2016 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AUP74_RS02300 7a6dd6008477ffc158ded267006c332b 611 Pfam PF00920 Dehydratase family 34 606 2.4E-218 T 11-11-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AUP74_RS02300 7a6dd6008477ffc158ded267006c332b 611 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 507 518 - T 11-11-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AUP74_RS02300 7a6dd6008477ffc158ded267006c332b 611 SUPERFAMILY SSF52016 419 609 6.83E-61 T 11-11-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel AUP74_RS00460 63b8f12ace3eeb17835398272c7e29d1 163 Pfam PF00583 Acetyltransferase (GNAT) family 65 145 2.7E-12 T 11-11-2016 IPR000182 GNAT domain GO:0008080 AUP74_RS00460 63b8f12ace3eeb17835398272c7e29d1 163 SUPERFAMILY SSF55729 16 147 1.44E-24 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS00460 63b8f12ace3eeb17835398272c7e29d1 163 Gene3D G3DSA:3.40.630.30 7 147 4.0E-25 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS03620 a4bef93420bfcc14168dae85e9f432fc 169 SMART SM00506 1 133 5.5E-23 T 11-11-2016 IPR002589 Macro domain AUP74_RS03620 a4bef93420bfcc14168dae85e9f432fc 169 Gene3D G3DSA:3.40.220.10 2 138 4.7E-35 T 11-11-2016 AUP74_RS03620 a4bef93420bfcc14168dae85e9f432fc 169 Pfam PF01661 Macro domain 20 131 2.0E-23 T 11-11-2016 IPR002589 Macro domain AUP74_RS03620 a4bef93420bfcc14168dae85e9f432fc 169 SUPERFAMILY SSF52949 2 154 5.72E-35 T 11-11-2016 AUP74_RS02555 05ed2fcad515debe9c98fb0057042557 608 Gene3D G3DSA:1.20.1560.10 32 342 8.8E-76 T 11-11-2016 AUP74_RS02555 05ed2fcad515debe9c98fb0057042557 608 TIGRFAM TIGR02204 MsbA_rel: ABC transporter, permease/ATP-binding protein 29 603 5.5E-259 T 11-11-2016 IPR011918 ABC transporter, ATP-binding/permease protein AUP74_RS02555 05ed2fcad515debe9c98fb0057042557 608 SMART SM00382 392 578 1.7E-18 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS02555 05ed2fcad515debe9c98fb0057042557 608 ProSitePatterns PS00211 ABC transporters family signature. 504 518 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AUP74_RS02555 05ed2fcad515debe9c98fb0057042557 608 Pfam PF00664 ABC transporter transmembrane region 45 313 7.0E-49 T 11-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 AUP74_RS02555 05ed2fcad515debe9c98fb0057042557 608 Gene3D G3DSA:3.40.50.300 365 590 3.8E-84 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS02555 05ed2fcad515debe9c98fb0057042557 608 SUPERFAMILY SSF52540 359 603 2.61E-90 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS02555 05ed2fcad515debe9c98fb0057042557 608 Pfam PF00005 ABC transporter 384 532 9.3E-34 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AUP74_RS02555 05ed2fcad515debe9c98fb0057042557 608 SUPERFAMILY SSF90123 33 344 2.75E-74 T 11-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 AUP74_RS08930 252ac35c6aebc09289e6cbaf72435501 595 SMART SM00490 261 342 7.5E-32 T 11-11-2016 IPR001650 Helicase, C-terminal AUP74_RS08930 252ac35c6aebc09289e6cbaf72435501 595 SUPERFAMILY SSF52540 76 363 8.19E-74 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS08930 252ac35c6aebc09289e6cbaf72435501 595 SMART SM00487 27 225 1.2E-63 T 11-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain AUP74_RS08930 252ac35c6aebc09289e6cbaf72435501 595 Pfam PF00270 DEAD/DEAH box helicase 33 198 5.9E-51 T 11-11-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AUP74_RS08930 252ac35c6aebc09289e6cbaf72435501 595 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 156 164 - T 11-11-2016 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site AUP74_RS08930 252ac35c6aebc09289e6cbaf72435501 595 Hamap MF_00964 ATP-dependent RNA helicase DeaD [deaD]. 3 552 45.72 T 11-11-2016 IPR028618 ATP-dependent RNA helicase DeaD GO:0000027|GO:0004004|GO:0070417 AUP74_RS08930 252ac35c6aebc09289e6cbaf72435501 595 Gene3D G3DSA:3.40.50.300 7 214 3.1E-80 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS08930 252ac35c6aebc09289e6cbaf72435501 595 Pfam PF03880 DbpA RNA binding domain 480 550 1.7E-24 T 11-11-2016 IPR005580 DbpA, RNA-binding domain AUP74_RS08930 252ac35c6aebc09289e6cbaf72435501 595 Pfam PF00271 Helicase conserved C-terminal domain 234 342 2.0E-29 T 11-11-2016 IPR001650 Helicase, C-terminal AUP74_RS08930 252ac35c6aebc09289e6cbaf72435501 595 Gene3D G3DSA:3.40.50.300 215 377 2.6E-53 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04205 31d14fccb96b575323999d6cef3bc2a5 459 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 249 455 2.0E-19 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AUP74_RS04205 31d14fccb96b575323999d6cef3bc2a5 459 SUPERFAMILY SSF161098 196 446 4.58E-30 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AUP74_RS04205 31d14fccb96b575323999d6cef3bc2a5 459 Gene3D G3DSA:1.10.3720.10 164 458 4.0E-39 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AUP74_RS04205 31d14fccb96b575323999d6cef3bc2a5 459 Pfam PF12501 Phosphate ATP-binding cassette transporter 8 177 4.2E-27 T 11-11-2016 IPR022182 ABC transporter phosphate permease PstC, N-terminal domain GO:0006817 AUP74_RS04205 31d14fccb96b575323999d6cef3bc2a5 459 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 161 454 2.0E-85 T 11-11-2016 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 AUP74_RS10355 f8b25e32267b88b1028f2802be1ee4ee 594 Pfam PF01103 Surface antigen 290 594 7.3E-47 T 11-11-2016 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020 AUP74_RS10355 f8b25e32267b88b1028f2802be1ee4ee 594 Gene3D G3DSA:2.40.160.50 277 594 3.1E-34 T 11-11-2016 AUP74_RS10355 f8b25e32267b88b1028f2802be1ee4ee 594 Pfam PF07244 Surface antigen variable number repeat 192 263 6.5E-9 T 11-11-2016 IPR010827 Surface antigen variable number GO:0019867 AUP74_RS00440 f5b3d2d38001318a62fcad4a739dde76 643 SUPERFAMILY SSF53383 146 534 1.9E-87 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase AUP74_RS00440 f5b3d2d38001318a62fcad4a739dde76 643 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 146 520 3.2E-91 T 11-11-2016 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 AUP74_RS00440 f5b3d2d38001318a62fcad4a739dde76 643 Gene3D G3DSA:3.90.1150.10 463 529 6.0E-8 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS00440 f5b3d2d38001318a62fcad4a739dde76 643 Gene3D G3DSA:3.90.100.10 530 624 3.8E-21 T 11-11-2016 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 AUP74_RS00440 f5b3d2d38001318a62fcad4a739dde76 643 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 580 624 5.4E-9 T 11-11-2016 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 AUP74_RS00440 f5b3d2d38001318a62fcad4a739dde76 643 SUPERFAMILY SSF55904 493 635 9.15E-27 T 11-11-2016 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 AUP74_RS00440 f5b3d2d38001318a62fcad4a739dde76 643 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 367 381 - T 11-11-2016 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 AUP74_RS00440 f5b3d2d38001318a62fcad4a739dde76 643 Gene3D G3DSA:3.40.640.10 146 426 5.7E-104 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AUP74_RS12265 cbfc3acb9486077d2cf6645fab6a96ee 284 SUPERFAMILY SSF54637 2 110 3.91E-37 T 11-11-2016 IPR029069 HotDog domain AUP74_RS12265 cbfc3acb9486077d2cf6645fab6a96ee 284 SUPERFAMILY SSF54637 112 277 1.16E-52 T 11-11-2016 IPR029069 HotDog domain AUP74_RS12265 cbfc3acb9486077d2cf6645fab6a96ee 284 Pfam PF13622 Thioesterase-like superfamily 28 276 5.3E-56 T 11-11-2016 AUP74_RS12265 cbfc3acb9486077d2cf6645fab6a96ee 284 Gene3D G3DSA:3.10.129.10 1 111 2.2E-42 T 11-11-2016 IPR029069 HotDog domain AUP74_RS12265 cbfc3acb9486077d2cf6645fab6a96ee 284 Gene3D G3DSA:3.10.129.10 123 277 1.2E-54 T 11-11-2016 IPR029069 HotDog domain AUP74_RS15545 4518f43954b0c5eebf94d4bcf338ae2f 300 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 7 300 59.084 T 11-11-2016 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 AUP74_RS15545 4518f43954b0c5eebf94d4bcf338ae2f 300 SUPERFAMILY SSF56349 9 288 5.89E-59 T 11-11-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AUP74_RS15545 4518f43954b0c5eebf94d4bcf338ae2f 300 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 13 299 2.9E-114 T 11-11-2016 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 AUP74_RS15545 4518f43954b0c5eebf94d4bcf338ae2f 300 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 9 300 58.133 T 11-11-2016 IPR023009 Tyrosine recombinase XerC/XerD AUP74_RS15545 4518f43954b0c5eebf94d4bcf338ae2f 300 Gene3D G3DSA:1.10.150.130 8 102 2.8E-30 T 11-11-2016 IPR023109 Integrase/recombinase, N-terminal AUP74_RS15545 4518f43954b0c5eebf94d4bcf338ae2f 300 Gene3D G3DSA:1.10.443.10 115 290 2.4E-57 T 11-11-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 AUP74_RS15545 4518f43954b0c5eebf94d4bcf338ae2f 300 Pfam PF00589 Phage integrase family 115 286 6.1E-51 T 11-11-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AUP74_RS15545 4518f43954b0c5eebf94d4bcf338ae2f 300 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 11 93 5.5E-24 T 11-11-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 AUP74_RS12605 37e65627560da2bedbddf9eb17a8b6f2 776 SUPERFAMILY SSF55821 177 396 8.85E-47 T 11-11-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain AUP74_RS12605 37e65627560da2bedbddf9eb17a8b6f2 776 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 10 756 2.4E-241 T 11-11-2016 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 AUP74_RS12605 37e65627560da2bedbddf9eb17a8b6f2 776 Gene3D G3DSA:3.30.420.40 673 730 2.3E-4 T 11-11-2016 AUP74_RS12605 37e65627560da2bedbddf9eb17a8b6f2 776 PIRSF PIRSF006256 3 766 1.3E-278 T 11-11-2016 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 AUP74_RS12605 37e65627560da2bedbddf9eb17a8b6f2 776 SUPERFAMILY SSF53067 609 741 7.99E-8 T 11-11-2016 AUP74_RS12605 37e65627560da2bedbddf9eb17a8b6f2 776 SUPERFAMILY SSF53067 490 538 7.99E-8 T 11-11-2016 AUP74_RS12605 37e65627560da2bedbddf9eb17a8b6f2 776 Gene3D G3DSA:3.90.870.10 203 384 3.1E-44 T 11-11-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain AUP74_RS12605 37e65627560da2bedbddf9eb17a8b6f2 776 Pfam PF01300 Telomere recombination 213 389 4.3E-50 T 11-11-2016 IPR006070 YrdC-like domain GO:0003725 AUP74_RS12605 37e65627560da2bedbddf9eb17a8b6f2 776 Pfam PF00708 Acylphosphatase 6 92 7.1E-21 T 11-11-2016 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 AUP74_RS12605 37e65627560da2bedbddf9eb17a8b6f2 776 Gene3D G3DSA:3.30.70.100 4 92 8.9E-25 T 11-11-2016 AUP74_RS12605 37e65627560da2bedbddf9eb17a8b6f2 776 Pfam PF07503 HypF finger 160 192 2.6E-15 T 11-11-2016 IPR011125 Zinc finger, HypF-type GO:0008270 AUP74_RS12605 37e65627560da2bedbddf9eb17a8b6f2 776 Pfam PF07503 HypF finger 111 143 2.3E-17 T 11-11-2016 IPR011125 Zinc finger, HypF-type GO:0008270 AUP74_RS12605 37e65627560da2bedbddf9eb17a8b6f2 776 SUPERFAMILY SSF54975 5 92 1.11E-21 T 11-11-2016 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 AUP74_RS12605 37e65627560da2bedbddf9eb17a8b6f2 776 ProSitePatterns PS00150 Acylphosphatase signature 1. 12 22 - T 11-11-2016 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 AUP74_RS04995 4fe0eef707a9851f7cce4fdf914c423a 2003 Gene3D G3DSA:1.10.1200.10 1666 1745 9.5E-18 T 11-11-2016 IPR009081 Phosphopantetheine binding ACP domain AUP74_RS04995 4fe0eef707a9851f7cce4fdf914c423a 2003 Gene3D G3DSA:1.10.1200.10 542 606 5.2E-23 T 11-11-2016 IPR009081 Phosphopantetheine binding ACP domain AUP74_RS04995 4fe0eef707a9851f7cce4fdf914c423a 2003 SUPERFAMILY SSF52777 812 1054 1.67E-61 T 11-11-2016 AUP74_RS04995 4fe0eef707a9851f7cce4fdf914c423a 2003 Gene3D G3DSA:2.160.10.10 1854 1987 9.9E-34 T 11-11-2016 AUP74_RS04995 4fe0eef707a9851f7cce4fdf914c423a 2003 SUPERFAMILY SSF56801 11 549 7.72E-129 T 11-11-2016 AUP74_RS04995 4fe0eef707a9851f7cce4fdf914c423a 2003 Gene3D G3DSA:3.30.300.30 423 541 6.2E-38 T 11-11-2016 AUP74_RS04995 4fe0eef707a9851f7cce4fdf914c423a 2003 SUPERFAMILY SSF52777 628 806 1.22E-42 T 11-11-2016 AUP74_RS04995 4fe0eef707a9851f7cce4fdf914c423a 2003 Gene3D G3DSA:3.40.50.980 1243 1389 4.7E-43 T 11-11-2016 AUP74_RS04995 4fe0eef707a9851f7cce4fdf914c423a 2003 Gene3D G3DSA:3.40.50.980 176 339 8.9E-26 T 11-11-2016 AUP74_RS04995 4fe0eef707a9851f7cce4fdf914c423a 2003 Gene3D G3DSA:3.40.50.980 1084 1242 9.5E-52 T 11-11-2016 AUP74_RS04995 4fe0eef707a9851f7cce4fdf914c423a 2003 Pfam PF00501 AMP-binding enzyme 1091 1483 3.8E-97 T 11-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 AUP74_RS04995 4fe0eef707a9851f7cce4fdf914c423a 2003 Pfam PF00501 AMP-binding enzyme 34 428 4.5E-75 T 11-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 AUP74_RS04995 4fe0eef707a9851f7cce4fdf914c423a 2003 SUPERFAMILY SSF51161 1849 1987 8.87E-29 T 11-11-2016 IPR011004 Trimeric LpxA-like AUP74_RS04995 4fe0eef707a9851f7cce4fdf914c423a 2003 Gene3D G3DSA:3.30.300.30 1477 1577 8.4E-35 T 11-11-2016 AUP74_RS04995 4fe0eef707a9851f7cce4fdf914c423a 2003 Gene3D G3DSA:2.30.38.10 1395 1473 2.7E-23 T 11-11-2016 AUP74_RS04995 4fe0eef707a9851f7cce4fdf914c423a 2003 Gene3D G3DSA:2.30.38.10 340 415 7.0E-22 T 11-11-2016 AUP74_RS04995 4fe0eef707a9851f7cce4fdf914c423a 2003 ProSitePatterns PS00012 Phosphopantetheine attachment site. 562 577 - T 11-11-2016 IPR006162 Phosphopantetheine attachment site AUP74_RS04995 4fe0eef707a9851f7cce4fdf914c423a 2003 SUPERFAMILY SSF47336 1670 1751 1.23E-15 T 11-11-2016 IPR009081 Phosphopantetheine binding ACP domain AUP74_RS04995 4fe0eef707a9851f7cce4fdf914c423a 2003 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1699 1714 - T 11-11-2016 IPR006162 Phosphopantetheine attachment site AUP74_RS04995 4fe0eef707a9851f7cce4fdf914c423a 2003 SUPERFAMILY SSF56801 1050 1575 6.15E-148 T 11-11-2016 AUP74_RS04995 4fe0eef707a9851f7cce4fdf914c423a 2003 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1112 1506 3.6E-127 T 11-11-2016 IPR010071 Amino acid adenylation domain AUP74_RS04995 4fe0eef707a9851f7cce4fdf914c423a 2003 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 48 452 1.9E-101 T 11-11-2016 IPR010071 Amino acid adenylation domain AUP74_RS04995 4fe0eef707a9851f7cce4fdf914c423a 2003 SMART SM00823 Phosphopantetheine attachment site 538 607 0.065 T 11-11-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AUP74_RS04995 4fe0eef707a9851f7cce4fdf914c423a 2003 SMART SM00823 Phosphopantetheine attachment site 1675 1744 7.2E-10 T 11-11-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AUP74_RS04995 4fe0eef707a9851f7cce4fdf914c423a 2003 Pfam PF00550 Phosphopantetheine attachment site 540 603 8.1E-13 T 11-11-2016 IPR009081 Phosphopantetheine binding ACP domain AUP74_RS04995 4fe0eef707a9851f7cce4fdf914c423a 2003 Pfam PF00550 Phosphopantetheine attachment site 1677 1740 7.2E-16 T 11-11-2016 IPR009081 Phosphopantetheine binding ACP domain AUP74_RS04995 4fe0eef707a9851f7cce4fdf914c423a 2003 Pfam PF13193 AMP-binding enzyme C-terminal domain 436 510 6.5E-12 T 11-11-2016 IPR025110 AMP-binding enzyme C-terminal domain AUP74_RS04995 4fe0eef707a9851f7cce4fdf914c423a 2003 Pfam PF13193 AMP-binding enzyme C-terminal domain 1491 1565 1.9E-9 T 11-11-2016 IPR025110 AMP-binding enzyme C-terminal domain AUP74_RS04995 4fe0eef707a9851f7cce4fdf914c423a 2003 Gene3D G3DSA:3.40.50.980 20 175 2.6E-40 T 11-11-2016 AUP74_RS04995 4fe0eef707a9851f7cce4fdf914c423a 2003 Pfam PF13745 HxxPF-repeated domain 948 1037 6.3E-25 T 11-11-2016 AUP74_RS04995 4fe0eef707a9851f7cce4fdf914c423a 2003 SUPERFAMILY SSF47336 531 603 7.46E-17 T 11-11-2016 IPR009081 Phosphopantetheine binding ACP domain AUP74_RS04995 4fe0eef707a9851f7cce4fdf914c423a 2003 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1233 1244 - T 11-11-2016 IPR020845 AMP-binding, conserved site AUP74_RS04995 4fe0eef707a9851f7cce4fdf914c423a 2003 ProSitePatterns PS00455 Putative AMP-binding domain signature. 170 181 - T 11-11-2016 IPR020845 AMP-binding, conserved site AUP74_RS04995 4fe0eef707a9851f7cce4fdf914c423a 2003 Pfam PF00668 Condensation domain 626 925 3.4E-73 T 11-11-2016 IPR001242 Condensation domain AUP74_RS05865 2a77c2900d862e66398fdfcc1eb7dfcd 401 Gene3D G3DSA:1.10.530.10 216 326 1.9E-52 T 11-11-2016 AUP74_RS05865 2a77c2900d862e66398fdfcc1eb7dfcd 401 Gene3D G3DSA:1.10.530.10 73 130 1.9E-52 T 11-11-2016 AUP74_RS05865 2a77c2900d862e66398fdfcc1eb7dfcd 401 Pfam PF01471 Putative peptidoglycan binding domain 343 397 2.0E-9 T 11-11-2016 IPR002477 Peptidoglycan binding-like AUP74_RS05865 2a77c2900d862e66398fdfcc1eb7dfcd 401 Pfam PF13406 Transglycosylase SLT domain 29 321 6.6E-101 T 11-11-2016 IPR031304 Transglycosylase SLT domain 2 AUP74_RS05865 2a77c2900d862e66398fdfcc1eb7dfcd 401 TIGRFAM TIGR02283 MltB_2: lytic murein transglycosylase 29 324 5.9E-112 T 11-11-2016 IPR011970 Lytic murein transglycosylase AUP74_RS05865 2a77c2900d862e66398fdfcc1eb7dfcd 401 SUPERFAMILY SSF47090 331 398 1.16E-12 T 11-11-2016 IPR002477 Peptidoglycan binding-like AUP74_RS05865 2a77c2900d862e66398fdfcc1eb7dfcd 401 SUPERFAMILY SSF53955 12 326 7.73E-98 T 11-11-2016 IPR023346 Lysozyme-like domain AUP74_RS05865 2a77c2900d862e66398fdfcc1eb7dfcd 401 Gene3D G3DSA:1.10.101.10 343 399 2.2E-10 T 11-11-2016 IPR002477 Peptidoglycan binding-like AUP74_RS09965 ea834028814737071551a5d5332afc72 246 Gene3D G3DSA:3.40.50.1820 2 64 5.1E-30 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS09965 ea834028814737071551a5d5332afc72 246 Gene3D G3DSA:3.40.50.1820 103 238 5.1E-30 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS09965 ea834028814737071551a5d5332afc72 246 SUPERFAMILY SSF53474 89 237 1.99E-25 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS09965 ea834028814737071551a5d5332afc72 246 SUPERFAMILY SSF53474 2 61 1.99E-25 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS09965 ea834028814737071551a5d5332afc72 246 Pfam PF00561 alpha/beta hydrolase fold 109 192 5.6E-7 T 11-11-2016 IPR000073 Alpha/beta hydrolase fold-1 AUP74_RS00325 0b4076671e8f754387ff221a82b06420 558 SUPERFAMILY SSF55729 313 467 1.85E-23 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS00325 0b4076671e8f754387ff221a82b06420 558 SMART SM00563 82 199 7.9E-7 T 11-11-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 AUP74_RS00325 0b4076671e8f754387ff221a82b06420 558 Pfam PF13444 Acetyltransferase (GNAT) domain 322 418 1.3E-20 T 11-11-2016 AUP74_RS00325 0b4076671e8f754387ff221a82b06420 558 SUPERFAMILY SSF69593 60 263 5.75E-14 T 11-11-2016 AUP74_RS00325 0b4076671e8f754387ff221a82b06420 558 Gene3D G3DSA:3.40.630.30 337 438 1.1E-9 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS00325 0b4076671e8f754387ff221a82b06420 558 Pfam PF01553 Acyltransferase 73 195 5.9E-9 T 11-11-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 AUP74_RS07875 409fd9f790e5ea8d274f1b0cddfcc9f7 301 Pfam PF13557 Putative MetA-pathway of phenol degradation 53 297 2.0E-47 T 11-11-2016 IPR025737 MetA-pathway of phenol degradation, putative AUP74_RS06000 1e54d6225e8cacf7a761f1c7310afe66 282 SUPERFAMILY SSF52374 1 281 3.44E-101 T 11-11-2016 AUP74_RS06000 1e54d6225e8cacf7a761f1c7310afe66 282 Gene3D G3DSA:3.30.1300.10 180 281 2.6E-28 T 11-11-2016 AUP74_RS06000 1e54d6225e8cacf7a761f1c7310afe66 282 Gene3D G3DSA:3.40.50.620 1 175 7.8E-74 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS06000 1e54d6225e8cacf7a761f1c7310afe66 282 Pfam PF02569 Pantoate-beta-alanine ligase 2 278 1.1E-98 T 11-11-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 AUP74_RS06000 1e54d6225e8cacf7a761f1c7310afe66 282 Hamap MF_00158 Pantothenate synthetase [panC]. 2 280 38.286 T 11-11-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 AUP74_RS06000 1e54d6225e8cacf7a761f1c7310afe66 282 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 280 6.1E-96 T 11-11-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 AUP74_RS15260 6995cd3792da6a6c99304c02dd5ea320 109 Pfam PF00893 Small Multidrug Resistance protein 1 93 8.7E-27 T 11-11-2016 IPR000390 Small multidrug resistance protein family GO:0016021 AUP74_RS15260 6995cd3792da6a6c99304c02dd5ea320 109 SUPERFAMILY SSF103481 4 105 5.1E-22 T 11-11-2016 AUP74_RS03910 c603205a4241c56b3e60df3f70ddadfb 635 Pfam PF12848 ABC transporter 220 298 3.1E-29 T 11-11-2016 IPR032781 ABC-transporter extension domain AUP74_RS03910 c603205a4241c56b3e60df3f70ddadfb 635 SMART SM00382 26 225 1.7E-13 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS03910 c603205a4241c56b3e60df3f70ddadfb 635 SMART SM00382 339 506 3.7E-15 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS03910 c603205a4241c56b3e60df3f70ddadfb 635 SUPERFAMILY SSF52540 121 257 1.63E-45 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03910 c603205a4241c56b3e60df3f70ddadfb 635 SUPERFAMILY SSF52540 2 92 1.63E-45 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03910 c603205a4241c56b3e60df3f70ddadfb 635 Gene3D G3DSA:3.40.50.300 312 525 7.1E-41 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03910 c603205a4241c56b3e60df3f70ddadfb 635 SUPERFAMILY SSF161270 533 616 4.71E-5 T 11-11-2016 AUP74_RS03910 c603205a4241c56b3e60df3f70ddadfb 635 SUPERFAMILY SSF52540 298 518 9.13E-44 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03910 c603205a4241c56b3e60df3f70ddadfb 635 ProSitePatterns PS00211 ABC transporters family signature. 433 447 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AUP74_RS03910 c603205a4241c56b3e60df3f70ddadfb 635 Pfam PF00005 ABC transporter 330 461 5.0E-21 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AUP74_RS03910 c603205a4241c56b3e60df3f70ddadfb 635 Pfam PF00005 ABC transporter 18 180 1.1E-21 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AUP74_RS03910 c603205a4241c56b3e60df3f70ddadfb 635 Gene3D G3DSA:3.40.50.300 2 277 1.0E-48 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS10755 8c5b521fc0aa68b016735dfa2a7c6f02 554 Pfam PF07969 Amidohydrolase family 59 548 7.4E-61 T 11-11-2016 IPR013108 Amidohydrolase 3 AUP74_RS10755 8c5b521fc0aa68b016735dfa2a7c6f02 554 Gene3D G3DSA:2.30.40.10 494 519 3.8E-7 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS10755 8c5b521fc0aa68b016735dfa2a7c6f02 554 SUPERFAMILY SSF51556 65 115 1.04E-28 T 11-11-2016 IPR032466 Metal-dependent hydrolase AUP74_RS10755 8c5b521fc0aa68b016735dfa2a7c6f02 554 SUPERFAMILY SSF51556 212 510 1.04E-28 T 11-11-2016 IPR032466 Metal-dependent hydrolase AUP74_RS10755 8c5b521fc0aa68b016735dfa2a7c6f02 554 Gene3D G3DSA:2.30.40.10 3 67 3.3E-12 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS10755 8c5b521fc0aa68b016735dfa2a7c6f02 554 Gene3D G3DSA:2.30.40.10 520 550 3.3E-12 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS10755 8c5b521fc0aa68b016735dfa2a7c6f02 554 Gene3D G3DSA:3.20.20.140 229 493 1.1E-19 T 11-11-2016 AUP74_RS10755 8c5b521fc0aa68b016735dfa2a7c6f02 554 SUPERFAMILY SSF51338 13 66 1.7E-8 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS10755 8c5b521fc0aa68b016735dfa2a7c6f02 554 SUPERFAMILY SSF51338 509 550 1.7E-8 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS09145 f95324bcf9e042b36f26afeb1da35add 375 Pfam PF04055 Radical SAM superfamily 112 287 2.3E-18 T 11-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 AUP74_RS09145 f95324bcf9e042b36f26afeb1da35add 375 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 8 356 74.171 T 11-11-2016 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AUP74_RS09145 f95324bcf9e042b36f26afeb1da35add 375 SUPERFAMILY SSF102114 102 332 4.32E-17 T 11-11-2016 AUP74_RS09145 f95324bcf9e042b36f26afeb1da35add 375 Gene3D G3DSA:3.20.20.70 109 336 2.8E-18 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS09145 f95324bcf9e042b36f26afeb1da35add 375 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 5 361 1.2E-143 T 11-11-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AUP74_RS09145 f95324bcf9e042b36f26afeb1da35add 375 PIRSF PIRSF006004 5 369 1.7E-149 T 11-11-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AUP74_RS05615 e739351e41fa6e6c1744b2ce609e8972 245 Gene3D G3DSA:3.40.50.880 1 245 4.8E-55 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS05615 e739351e41fa6e6c1744b2ce609e8972 245 Pfam PF17124 ThiJ/PfpI family-like 8 202 7.9E-47 T 11-11-2016 IPR032633 ThiJ/PfpI family-like AUP74_RS05615 e739351e41fa6e6c1744b2ce609e8972 245 SUPERFAMILY SSF52317 3 245 3.55E-43 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS16870 a49e782ea659e948b76718a2f06326ff 142 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 4 140 6.0E-65 T 11-11-2016 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS16870 a49e782ea659e948b76718a2f06326ff 142 SUPERFAMILY SSF52161 1 138 3.01E-59 T 11-11-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 AUP74_RS16870 a49e782ea659e948b76718a2f06326ff 142 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 11-11-2016 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 AUP74_RS16870 a49e782ea659e948b76718a2f06326ff 142 Pfam PF00572 Ribosomal protein L13 15 137 4.1E-58 T 11-11-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 AUP74_RS16870 a49e782ea659e948b76718a2f06326ff 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 141 28.72 T 11-11-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 AUP74_RS16870 a49e782ea659e948b76718a2f06326ff 142 PIRSF PIRSF002181 1 142 2.1E-50 T 11-11-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 AUP74_RS16870 a49e782ea659e948b76718a2f06326ff 142 Gene3D G3DSA:3.90.1180.10 3 140 3.4E-64 T 11-11-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 AUP74_RS08645 d6aeeeded975b5ef67ecb0bb263bd0d4 399 Gene3D G3DSA:3.90.1150.10 283 395 7.2E-30 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS08645 d6aeeeded975b5ef67ecb0bb263bd0d4 399 Gene3D G3DSA:3.40.640.10 52 282 1.7E-77 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AUP74_RS08645 d6aeeeded975b5ef67ecb0bb263bd0d4 399 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 242 255 - T 11-11-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 AUP74_RS08645 d6aeeeded975b5ef67ecb0bb263bd0d4 399 SUPERFAMILY SSF53383 16 394 3.06E-111 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase AUP74_RS08645 d6aeeeded975b5ef67ecb0bb263bd0d4 399 Pfam PF00155 Aminotransferase class I and II 40 389 1.0E-66 T 11-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AUP74_RS13650 0323628b6558c65ec708cabfaf4946b7 332 SUPERFAMILY SSF46689 278 327 2.11E-11 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS13650 0323628b6558c65ec708cabfaf4946b7 332 Pfam PF12833 Helix-turn-helix domain 250 325 1.8E-12 T 11-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AUP74_RS13650 0323628b6558c65ec708cabfaf4946b7 332 Gene3D G3DSA:1.10.10.60 282 326 3.7E-13 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS13650 0323628b6558c65ec708cabfaf4946b7 332 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 16 200 1.7E-36 T 11-11-2016 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal AUP74_RS13650 0323628b6558c65ec708cabfaf4946b7 332 SMART SM00342 242 324 5.1E-17 T 11-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AUP74_RS00780 0151d1909abefbab41894ad7080c55f6 497 Gene3D G3DSA:3.30.750.24 396 485 2.4E-9 T 11-11-2016 IPR002645 STAS domain AUP74_RS00780 0151d1909abefbab41894ad7080c55f6 497 SUPERFAMILY SSF52091 393 486 5.89E-13 T 11-11-2016 IPR002645 STAS domain AUP74_RS00780 0151d1909abefbab41894ad7080c55f6 497 Pfam PF01740 STAS domain 397 488 1.4E-11 T 11-11-2016 IPR002645 STAS domain AUP74_RS00780 0151d1909abefbab41894ad7080c55f6 497 Pfam PF00916 Sulfate permease family 15 143 1.3E-25 T 11-11-2016 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 AUP74_RS00780 0151d1909abefbab41894ad7080c55f6 497 Pfam PF00916 Sulfate permease family 170 346 5.6E-27 T 11-11-2016 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 AUP74_RS00780 0151d1909abefbab41894ad7080c55f6 497 ProSitePatterns PS01130 SLC26A transporters signature. 43 64 - T 11-11-2016 IPR018045 Sulphate anion transporter, conserved site GO:0008271|GO:0008272 AUP74_RS16050 f7bbb2ba3fda1ae46f4b57a6d21dce28 495 Gene3D G3DSA:3.40.50.2020 272 443 6.1E-44 T 11-11-2016 IPR029057 Phosphoribosyltransferase-like AUP74_RS16050 f7bbb2ba3fda1ae46f4b57a6d21dce28 495 SUPERFAMILY SSF56235 2 257 7.72E-71 T 11-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal AUP74_RS16050 f7bbb2ba3fda1ae46f4b57a6d21dce28 495 Gene3D G3DSA:3.60.20.10 2 258 8.3E-61 T 11-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal AUP74_RS16050 f7bbb2ba3fda1ae46f4b57a6d21dce28 495 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 466 43.962 T 11-11-2016 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 AUP74_RS16050 f7bbb2ba3fda1ae46f4b57a6d21dce28 495 Pfam PF13522 Glutamine amidotransferase domain 64 208 8.5E-14 T 11-11-2016 AUP74_RS16050 f7bbb2ba3fda1ae46f4b57a6d21dce28 495 PIRSF PIRSF000485 1 481 1.1E-159 T 11-11-2016 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 AUP74_RS16050 f7bbb2ba3fda1ae46f4b57a6d21dce28 495 Pfam PF00156 Phosphoribosyl transferase domain 272 393 2.8E-10 T 11-11-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 AUP74_RS16050 f7bbb2ba3fda1ae46f4b57a6d21dce28 495 SUPERFAMILY SSF53271 250 483 4.59E-71 T 11-11-2016 IPR029057 Phosphoribosyltransferase-like AUP74_RS16050 f7bbb2ba3fda1ae46f4b57a6d21dce28 495 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 2 464 9.6E-157 T 11-11-2016 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 AUP74_RS11200 48f2e3f6dde5678ca480aff42a65f91e 437 TIGRFAM TIGR00115 tig: trigger factor 11 415 7.1E-145 T 11-11-2016 IPR005215 Trigger factor GO:0015031 AUP74_RS11200 48f2e3f6dde5678ca480aff42a65f91e 437 Gene3D G3DSA:3.30.70.1050 1 117 1.3E-40 T 11-11-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 AUP74_RS11200 48f2e3f6dde5678ca480aff42a65f91e 437 SUPERFAMILY SSF109998 248 432 4.19E-47 T 11-11-2016 IPR027304 Trigger factor/SurA domain AUP74_RS11200 48f2e3f6dde5678ca480aff42a65f91e 437 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 264 416 1.8E-36 T 11-11-2016 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 AUP74_RS11200 48f2e3f6dde5678ca480aff42a65f91e 437 SUPERFAMILY SSF54534 88 239 2.16E-39 T 11-11-2016 AUP74_RS11200 48f2e3f6dde5678ca480aff42a65f91e 437 Hamap MF_00303 Trigger factor [tig]. 1 421 22.189 T 11-11-2016 IPR005215 Trigger factor GO:0015031 AUP74_RS11200 48f2e3f6dde5678ca480aff42a65f91e 437 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 155 237 6.5E-18 T 11-11-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 AUP74_RS11200 48f2e3f6dde5678ca480aff42a65f91e 437 Gene3D G3DSA:3.10.50.40 153 216 3.4E-15 T 11-11-2016 AUP74_RS11200 48f2e3f6dde5678ca480aff42a65f91e 437 SUPERFAMILY SSF102735 1 131 1.44E-41 T 11-11-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 AUP74_RS11200 48f2e3f6dde5678ca480aff42a65f91e 437 Pfam PF05697 Bacterial trigger factor protein (TF) 1 142 1.4E-43 T 11-11-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 AUP74_RS11200 48f2e3f6dde5678ca480aff42a65f91e 437 Gene3D G3DSA:1.10.3120.10 217 392 5.4E-57 T 11-11-2016 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 AUP74_RS11200 48f2e3f6dde5678ca480aff42a65f91e 437 PIRSF PIRSF003095 1 436 1.6E-131 T 11-11-2016 IPR005215 Trigger factor GO:0015031 AUP74_RS10415 ffccfb75cf998dd3680661e97be1ffa8 333 Gene3D G3DSA:3.20.20.70 9 251 3.8E-65 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS10415 ffccfb75cf998dd3680661e97be1ffa8 333 PIRSF PIRSF006621 1 333 1.6E-76 T 11-11-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 AUP74_RS10415 ffccfb75cf998dd3680661e97be1ffa8 333 SUPERFAMILY SSF51395 10 310 2.75E-72 T 11-11-2016 AUP74_RS10415 ffccfb75cf998dd3680661e97be1ffa8 333 Hamap MF_02043 tRNA-dihydrouridine(16) synthase [dusC]. 17 323 50.512 T 11-11-2016 IPR032886 tRNA-dihydrouridine(16) synthase GO:0002943|GO:0017150 AUP74_RS10415 ffccfb75cf998dd3680661e97be1ffa8 333 Pfam PF01207 Dihydrouridine synthase (Dus) 14 313 5.2E-72 T 11-11-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 AUP74_RS10415 ffccfb75cf998dd3680661e97be1ffa8 333 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 101 119 - T 11-11-2016 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 AUP74_RS01365 87deb60436cc3a2de0cff3c79626db0e 317 SUPERFAMILY SSF143865 14 256 1.12E-32 T 11-11-2016 AUP74_RS01365 87deb60436cc3a2de0cff3c79626db0e 317 SUPERFAMILY SSF144083 252 315 3.14E-20 T 11-11-2016 AUP74_RS01365 87deb60436cc3a2de0cff3c79626db0e 317 Gene3D G3DSA:1.20.58.340 241 317 9.0E-27 T 11-11-2016 AUP74_RS01365 87deb60436cc3a2de0cff3c79626db0e 317 Pfam PF01544 CorA-like Mg2+ transporter protein 28 313 2.7E-57 T 11-11-2016 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 AUP74_RS01365 87deb60436cc3a2de0cff3c79626db0e 317 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 13 317 1.1E-75 T 11-11-2016 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 AUP74_RS12925 0c3c8014eaccf52fc4f6985426eff5a7 158 SUPERFAMILY SSF89562 2 157 1.2E-51 T 11-11-2016 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein AUP74_RS12925 0c3c8014eaccf52fc4f6985426eff5a7 158 Pfam PF03737 Demethylmenaquinone methyltransferase 4 152 3.0E-46 T 11-11-2016 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein AUP74_RS12925 0c3c8014eaccf52fc4f6985426eff5a7 158 Gene3D G3DSA:3.50.30.40 2 156 2.3E-56 T 11-11-2016 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein AUP74_RS12925 0c3c8014eaccf52fc4f6985426eff5a7 158 TIGRFAM TIGR01935 NOT-MenG: RraA family 4 153 1.5E-68 T 11-11-2016 IPR010203 Regulator of ribonuclease activity A GO:0008428|GO:0051252 AUP74_RS01660 fa1cb94c2b345674acd1932991644f47 244 Pfam PF03922 OmpW family 27 244 4.9E-47 T 11-11-2016 IPR005618 Outer membrane protein, OmpW GO:0019867 AUP74_RS01660 fa1cb94c2b345674acd1932991644f47 244 SUPERFAMILY SSF56925 27 244 1.2E-19 T 11-11-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AUP74_RS01660 fa1cb94c2b345674acd1932991644f47 244 ProSitePatterns PS00695 Enterobacterial virulence outer membrane protein signature 2. 236 244 - T 11-11-2016 IPR000758 Virulence-related outer membrane protein GO:0009279 AUP74_RS01660 fa1cb94c2b345674acd1932991644f47 244 Gene3D G3DSA:2.40.160.20 26 244 4.5E-50 T 11-11-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AUP74_RS13315 a2c99d311c8500ee83b6572fe04e454b 450 TIGRFAM TIGR04381 HTH_TypR: TyrR family helix-turn-helix domain 395 440 1.1E-18 T 11-11-2016 IPR030828 TyrR family, helix-turn-helix domain GO:0003677 AUP74_RS13315 a2c99d311c8500ee83b6572fe04e454b 450 Pfam PF13188 PAS domain 58 108 5.3E-6 T 11-11-2016 IPR000014 PAS domain AUP74_RS13315 a2c99d311c8500ee83b6572fe04e454b 450 Gene3D G3DSA:3.30.450.20 56 115 4.4E-9 T 11-11-2016 AUP74_RS13315 a2c99d311c8500ee83b6572fe04e454b 450 SUPERFAMILY SSF55785 57 117 3.49E-9 T 11-11-2016 IPR000014 PAS domain AUP74_RS13315 a2c99d311c8500ee83b6572fe04e454b 450 Pfam PF14532 Sigma-54 interaction domain 188 307 3.8E-10 T 11-11-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 AUP74_RS13315 a2c99d311c8500ee83b6572fe04e454b 450 SUPERFAMILY SSF52540 182 366 4.88E-22 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS13315 a2c99d311c8500ee83b6572fe04e454b 450 Gene3D G3DSA:1.10.8.60 316 375 8.7E-6 T 11-11-2016 AUP74_RS13315 a2c99d311c8500ee83b6572fe04e454b 450 SUPERFAMILY SSF46689 384 439 3.94E-8 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS13315 a2c99d311c8500ee83b6572fe04e454b 450 Gene3D G3DSA:1.10.10.60 388 439 2.2E-19 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS13315 a2c99d311c8500ee83b6572fe04e454b 450 Gene3D G3DSA:3.40.50.300 186 308 1.1E-14 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS02845 cf5e642a170126a0b043eec7e6c0b018 101 Pfam PF09413 Putative prokaryotic signal transducing protein 1 67 8.2E-16 T 11-11-2016 IPR018551 Domain of unknown function DUF2007 AUP74_RS02845 cf5e642a170126a0b043eec7e6c0b018 101 SUPERFAMILY SSF90209 71 100 6.91E-5 T 11-11-2016 IPR001876 Zinc finger, RanBP2-type GO:0008270 AUP74_RS02845 cf5e642a170126a0b043eec7e6c0b018 101 ProSitePatterns PS01358 Zinc finger RanBP2-type signature. 75 94 - T 11-11-2016 IPR001876 Zinc finger, RanBP2-type GO:0008270 AUP74_RS04745 dc502248c26529854dc4bb0fefcb0cca 128 Pfam PF04134 Protein of unknown function, DUF393 4 111 1.3E-25 T 11-11-2016 IPR007263 Protein of unknown function DUF393 AUP74_RS05700 31215c48227c9d52bd75651457ca7047 167 SUPERFAMILY SSF50341 22 161 8.37E-30 T 11-11-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 AUP74_RS05700 31215c48227c9d52bd75651457ca7047 167 Gene3D G3DSA:2.40.50.180 61 107 2.4E-7 T 11-11-2016 AUP74_RS05700 31215c48227c9d52bd75651457ca7047 167 SMART SM00260 19 156 1.0E-17 T 11-11-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 AUP74_RS05700 31215c48227c9d52bd75651457ca7047 167 Pfam PF01584 CheW-like domain 25 159 7.7E-26 T 11-11-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 AUP74_RS11370 ff661f6389a02a06fa0d4ae47c2d6b05 175 Pfam PF14345 GDYXXLXY protein 18 170 6.2E-34 T 11-11-2016 IPR025833 GDYXXLXY protein AUP74_RS12805 f917b0abd1f69819d8215926f7063706 316 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 299 2.0E-53 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS12805 f917b0abd1f69819d8215926f7063706 316 Gene3D G3DSA:3.50.50.60 231 312 6.1E-12 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS12805 f917b0abd1f69819d8215926f7063706 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 7 29 5.7E-78 T 11-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AUP74_RS12805 f917b0abd1f69819d8215926f7063706 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 105 113 5.7E-78 T 11-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AUP74_RS12805 f917b0abd1f69819d8215926f7063706 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 61 71 5.7E-78 T 11-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AUP74_RS12805 f917b0abd1f69819d8215926f7063706 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 142 166 5.7E-78 T 11-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AUP74_RS12805 f917b0abd1f69819d8215926f7063706 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 236 257 5.7E-78 T 11-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AUP74_RS12805 f917b0abd1f69819d8215926f7063706 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 197 213 5.7E-78 T 11-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AUP74_RS12805 f917b0abd1f69819d8215926f7063706 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 40 55 5.7E-78 T 11-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AUP74_RS12805 f917b0abd1f69819d8215926f7063706 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 127 139 5.7E-78 T 11-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AUP74_RS12805 f917b0abd1f69819d8215926f7063706 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 274 292 5.7E-78 T 11-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AUP74_RS12805 f917b0abd1f69819d8215926f7063706 316 SUPERFAMILY SSF51905 2 311 4.99E-54 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS12805 f917b0abd1f69819d8215926f7063706 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 2.0E-42 T 11-11-2016 AUP74_RS12805 f917b0abd1f69819d8215926f7063706 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 2.0E-42 T 11-11-2016 AUP74_RS12805 f917b0abd1f69819d8215926f7063706 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 2.0E-42 T 11-11-2016 AUP74_RS12805 f917b0abd1f69819d8215926f7063706 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 286 2.0E-42 T 11-11-2016 AUP74_RS12805 f917b0abd1f69819d8215926f7063706 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 2.0E-42 T 11-11-2016 AUP74_RS12805 f917b0abd1f69819d8215926f7063706 316 Gene3D G3DSA:3.50.50.60 117 230 1.8E-35 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS12805 f917b0abd1f69819d8215926f7063706 316 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 7 311 5.1E-125 T 11-11-2016 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00240+1.8.1.9|KEGG: 00450+1.8.1.9 AUP74_RS12805 f917b0abd1f69819d8215926f7063706 316 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 134 154 - T 11-11-2016 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 AUP74_RS12805 f917b0abd1f69819d8215926f7063706 316 Gene3D G3DSA:3.50.50.60 3 116 7.8E-32 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS13065 7d1c7273a9f9b781c40ab1dc19b9b88e 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 6.9E-49 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS13065 7d1c7273a9f9b781c40ab1dc19b9b88e 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 6.9E-49 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS13065 7d1c7273a9f9b781c40ab1dc19b9b88e 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 6.9E-49 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS13065 7d1c7273a9f9b781c40ab1dc19b9b88e 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 6.9E-49 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS13065 7d1c7273a9f9b781c40ab1dc19b9b88e 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 6.9E-49 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS13065 7d1c7273a9f9b781c40ab1dc19b9b88e 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 6.9E-49 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS13065 7d1c7273a9f9b781c40ab1dc19b9b88e 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.5E-12 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS13065 7d1c7273a9f9b781c40ab1dc19b9b88e 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.5E-12 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS13065 7d1c7273a9f9b781c40ab1dc19b9b88e 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 1.5E-12 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS13065 7d1c7273a9f9b781c40ab1dc19b9b88e 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 11-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AUP74_RS13065 7d1c7273a9f9b781c40ab1dc19b9b88e 251 SUPERFAMILY SSF51735 8 250 8.11E-84 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS13065 7d1c7273a9f9b781c40ab1dc19b9b88e 251 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 189 9.8E-6 T 11-11-2016 AUP74_RS13065 7d1c7273a9f9b781c40ab1dc19b9b88e 251 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 12 249 5.0E-98 T 11-11-2016 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 AUP74_RS13065 7d1c7273a9f9b781c40ab1dc19b9b88e 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 248 2.3E-63 T 11-11-2016 AUP74_RS13065 7d1c7273a9f9b781c40ab1dc19b9b88e 251 Gene3D G3DSA:3.40.50.720 4 250 1.8E-87 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS11545 c8daf1634364249aa7a5736ffa81788a 256 SUPERFAMILY SSF48613 26 232 1.76E-14 T 11-11-2016 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 AUP74_RS11545 c8daf1634364249aa7a5736ffa81788a 256 Gene3D G3DSA:1.20.910.10 4 220 2.4E-16 T 11-11-2016 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 AUP74_RS11545 c8daf1634364249aa7a5736ffa81788a 256 Pfam PF14518 Iron-containing redox enzyme 42 220 3.2E-8 T 11-11-2016 IPR028201 PqqC-like protein AUP74_RS03060 e0c0059f723a30771b66b66b68627fe3 126 SUPERFAMILY SSF54593 2 125 7.61E-22 T 11-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AUP74_RS03060 e0c0059f723a30771b66b66b68627fe3 126 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 119 5.5E-5 T 11-11-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AUP74_RS03060 e0c0059f723a30771b66b66b68627fe3 126 Gene3D G3DSA:3.10.180.10 1 121 2.0E-21 T 11-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AUP74_RS16130 8c7abcdd09a40061914162720422e671 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 3.5E-23 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS16130 8c7abcdd09a40061914162720422e671 297 Gene3D G3DSA:3.40.190.10 177 249 1.3E-17 T 11-11-2016 AUP74_RS16130 8c7abcdd09a40061914162720422e671 297 Gene3D G3DSA:3.40.190.10 90 176 3.0E-18 T 11-11-2016 AUP74_RS16130 8c7abcdd09a40061914162720422e671 297 SUPERFAMILY SSF46785 1 111 1.19E-28 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS16130 8c7abcdd09a40061914162720422e671 297 Gene3D G3DSA:1.10.10.10 1 87 1.6E-32 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS16130 8c7abcdd09a40061914162720422e671 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.7E-10 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS16130 8c7abcdd09a40061914162720422e671 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.7E-10 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS16130 8c7abcdd09a40061914162720422e671 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.7E-10 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS16130 8c7abcdd09a40061914162720422e671 297 Pfam PF03466 LysR substrate binding domain 87 288 1.4E-44 T 11-11-2016 IPR005119 LysR, substrate-binding AUP74_RS16130 8c7abcdd09a40061914162720422e671 297 SUPERFAMILY SSF53850 88 292 4.85E-45 T 11-11-2016 AUP74_RS02885 5b6f7a1bb27333769ba2bb85f5e7708e 387 Gene3D G3DSA:3.40.50.1260 4 174 1.4E-65 T 11-11-2016 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS02885 5b6f7a1bb27333769ba2bb85f5e7708e 387 PIRSF PIRSF000724 1 387 9.1E-137 T 11-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS02885 5b6f7a1bb27333769ba2bb85f5e7708e 387 PRINTS PR00477 Phosphoglycerate kinase family signature 359 376 5.4E-81 T 11-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS02885 5b6f7a1bb27333769ba2bb85f5e7708e 387 PRINTS PR00477 Phosphoglycerate kinase family signature 336 347 5.4E-81 T 11-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS02885 5b6f7a1bb27333769ba2bb85f5e7708e 387 PRINTS PR00477 Phosphoglycerate kinase family signature 104 119 5.4E-81 T 11-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS02885 5b6f7a1bb27333769ba2bb85f5e7708e 387 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 5.4E-81 T 11-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS02885 5b6f7a1bb27333769ba2bb85f5e7708e 387 PRINTS PR00477 Phosphoglycerate kinase family signature 303 328 5.4E-81 T 11-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS02885 5b6f7a1bb27333769ba2bb85f5e7708e 387 PRINTS PR00477 Phosphoglycerate kinase family signature 132 154 5.4E-81 T 11-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS02885 5b6f7a1bb27333769ba2bb85f5e7708e 387 PRINTS PR00477 Phosphoglycerate kinase family signature 186 205 5.4E-81 T 11-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS02885 5b6f7a1bb27333769ba2bb85f5e7708e 387 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 5.4E-81 T 11-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS02885 5b6f7a1bb27333769ba2bb85f5e7708e 387 PRINTS PR00477 Phosphoglycerate kinase family signature 163 185 5.4E-81 T 11-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS02885 5b6f7a1bb27333769ba2bb85f5e7708e 387 Gene3D G3DSA:3.40.50.1270 175 371 2.7E-83 T 11-11-2016 IPR015901 Phosphoglycerate kinase, C-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS02885 5b6f7a1bb27333769ba2bb85f5e7708e 387 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 383 39.929 T 11-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS02885 5b6f7a1bb27333769ba2bb85f5e7708e 387 Pfam PF00162 Phosphoglycerate kinase 6 373 1.1E-142 T 11-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS02885 5b6f7a1bb27333769ba2bb85f5e7708e 387 SUPERFAMILY SSF53748 4 383 4.36E-147 T 11-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS14815 e69baee0e01268b40b8f795364853406 359 Pfam PF00266 Aminotransferase class-V 4 347 2.0E-47 T 11-11-2016 IPR000192 Aminotransferase class V domain AUP74_RS14815 e69baee0e01268b40b8f795364853406 359 SUPERFAMILY SSF53383 2 357 7.71E-111 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase AUP74_RS14815 e69baee0e01268b40b8f795364853406 359 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 1 358 50.377 T 11-11-2016 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 AUP74_RS14815 e69baee0e01268b40b8f795364853406 359 PIRSF PIRSF000525 1 359 4.6E-146 T 11-11-2016 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 AUP74_RS14815 e69baee0e01268b40b8f795364853406 359 Gene3D G3DSA:3.40.640.10 16 256 2.6E-100 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AUP74_RS14815 e69baee0e01268b40b8f795364853406 359 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 4 357 5.9E-152 T 11-11-2016 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 AUP74_RS14815 e69baee0e01268b40b8f795364853406 359 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 186 205 - T 11-11-2016 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site AUP74_RS14815 e69baee0e01268b40b8f795364853406 359 Gene3D G3DSA:3.90.1150.10 257 357 2.7E-41 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS05065 c0dded18c0db26a7f0f1a53b3090ff9f 742 Gene3D G3DSA:3.40.50.300 524 707 4.6E-34 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05065 c0dded18c0db26a7f0f1a53b3090ff9f 742 Pfam PF02706 Chain length determinant protein 6 177 6.1E-19 T 11-11-2016 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 AUP74_RS05065 c0dded18c0db26a7f0f1a53b3090ff9f 742 SUPERFAMILY SSF52540 524 708 1.11E-37 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05065 c0dded18c0db26a7f0f1a53b3090ff9f 742 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 528 708 1.1E-11 T 11-11-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain AUP74_RS05065 c0dded18c0db26a7f0f1a53b3090ff9f 742 Pfam PF13807 G-rich domain on putative tyrosine kinase 377 448 2.2E-8 T 11-11-2016 IPR032807 Tyrosine kinase, G-rich domain AUP74_RS05065 c0dded18c0db26a7f0f1a53b3090ff9f 742 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 501 710 2.6E-47 T 11-11-2016 IPR005702 Exopolysaccharide synthesis protein GO:0045226 AUP74_RS02630 3bd23bf1f731be6ad1348fbbffed43d1 347 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 30 211 4.0E-44 T 11-11-2016 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal AUP74_RS02630 3bd23bf1f731be6ad1348fbbffed43d1 347 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 324 340 6.6E-6 T 11-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AUP74_RS02630 3bd23bf1f731be6ad1348fbbffed43d1 347 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 309 324 6.6E-6 T 11-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AUP74_RS02630 3bd23bf1f731be6ad1348fbbffed43d1 347 Gene3D G3DSA:1.10.10.60 293 343 2.1E-15 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS02630 3bd23bf1f731be6ad1348fbbffed43d1 347 SMART SM00342 258 340 6.6E-24 T 11-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AUP74_RS02630 3bd23bf1f731be6ad1348fbbffed43d1 347 SUPERFAMILY SSF46689 293 343 3.54E-13 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS02630 3bd23bf1f731be6ad1348fbbffed43d1 347 Pfam PF12833 Helix-turn-helix domain 264 341 3.6E-20 T 11-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AUP74_RS02630 3bd23bf1f731be6ad1348fbbffed43d1 347 Gene3D G3DSA:1.10.10.60 238 282 4.0E-5 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS00970 5a95e5f7cea41ad90764875f85c126d5 472 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 89 115 4.2E-7 T 11-11-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AUP74_RS00970 5a95e5f7cea41ad90764875f85c126d5 472 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 307 326 4.2E-7 T 11-11-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AUP74_RS00970 5a95e5f7cea41ad90764875f85c126d5 472 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 13 34 4.2E-7 T 11-11-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AUP74_RS00970 5a95e5f7cea41ad90764875f85c126d5 472 Pfam PF00209 Sodium:neurotransmitter symporter family 144 462 4.6E-26 T 11-11-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AUP74_RS00970 5a95e5f7cea41ad90764875f85c126d5 472 Pfam PF00209 Sodium:neurotransmitter symporter family 5 125 1.0E-23 T 11-11-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AUP74_RS00970 5a95e5f7cea41ad90764875f85c126d5 472 SUPERFAMILY SSF161070 5 462 6.93E-113 T 11-11-2016 AUP74_RS08525 94efacc520a11376625c5252e2bedc2b 871 Gene3D G3DSA:3.40.50.1700 430 664 4.5E-63 T 11-11-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 AUP74_RS08525 94efacc520a11376625c5252e2bedc2b 871 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 84 407 3.3E-84 T 11-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AUP74_RS08525 94efacc520a11376625c5252e2bedc2b 871 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 444 664 2.1E-31 T 11-11-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 AUP74_RS08525 94efacc520a11376625c5252e2bedc2b 871 Gene3D G3DSA:3.20.20.300 63 417 1.7E-112 T 11-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AUP74_RS08525 94efacc520a11376625c5252e2bedc2b 871 SUPERFAMILY SSF52279 444 663 3.14E-44 T 11-11-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 AUP74_RS08525 94efacc520a11376625c5252e2bedc2b 871 PRINTS PR00133 Glycosyl hydrolase family 3 signature 219 235 6.4E-22 T 11-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AUP74_RS08525 94efacc520a11376625c5252e2bedc2b 871 PRINTS PR00133 Glycosyl hydrolase family 3 signature 173 192 6.4E-22 T 11-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AUP74_RS08525 94efacc520a11376625c5252e2bedc2b 871 PRINTS PR00133 Glycosyl hydrolase family 3 signature 330 348 6.4E-22 T 11-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AUP74_RS08525 94efacc520a11376625c5252e2bedc2b 871 PRINTS PR00133 Glycosyl hydrolase family 3 signature 260 276 6.4E-22 T 11-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AUP74_RS08525 94efacc520a11376625c5252e2bedc2b 871 PRINTS PR00133 Glycosyl hydrolase family 3 signature 149 165 6.4E-22 T 11-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AUP74_RS08525 94efacc520a11376625c5252e2bedc2b 871 SUPERFAMILY SSF51445 64 443 4.32E-114 T 11-11-2016 IPR017853 Glycoside hydrolase superfamily AUP74_RS02950 4a349feacb2750eb992b105208fa6146 878 Pfam PF00593 TonB dependent receptor 608 877 4.0E-37 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS02950 4a349feacb2750eb992b105208fa6146 878 Gene3D G3DSA:2.170.130.10 43 172 4.2E-18 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS02950 4a349feacb2750eb992b105208fa6146 878 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 861 878 - T 11-11-2016 IPR010917 TonB-dependent receptor, conserved site AUP74_RS02950 4a349feacb2750eb992b105208fa6146 878 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 42 878 4.5E-184 T 11-11-2016 IPR010104 Bacterial TonB-dependent receptor AUP74_RS02950 4a349feacb2750eb992b105208fa6146 878 Gene3D G3DSA:2.40.170.20 438 473 1.3E-66 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS02950 4a349feacb2750eb992b105208fa6146 878 Gene3D G3DSA:2.40.170.20 173 305 1.3E-66 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS02950 4a349feacb2750eb992b105208fa6146 878 Gene3D G3DSA:2.40.170.20 532 878 1.3E-66 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS02950 4a349feacb2750eb992b105208fa6146 878 Gene3D G3DSA:2.40.170.20 355 400 1.3E-66 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS02950 4a349feacb2750eb992b105208fa6146 878 Pfam PF07715 TonB-dependent Receptor Plug Domain 60 172 9.4E-16 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS02950 4a349feacb2750eb992b105208fa6146 878 SUPERFAMILY SSF56935 512 878 1.17E-93 T 11-11-2016 AUP74_RS02950 4a349feacb2750eb992b105208fa6146 878 SUPERFAMILY SSF56935 33 236 1.17E-93 T 11-11-2016 AUP74_RS02950 4a349feacb2750eb992b105208fa6146 878 SUPERFAMILY SSF56935 271 478 1.17E-93 T 11-11-2016 AUP74_RS15790 d38d1ca762b97e7eddc26efff512d99f 356 Gene3D G3DSA:3.30.1330.60 249 355 1.5E-42 T 11-11-2016 IPR006665 OmpA-like domain AUP74_RS15790 d38d1ca762b97e7eddc26efff512d99f 356 Gene3D G3DSA:4.10.1080.10 206 244 6.6E-6 T 11-11-2016 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 AUP74_RS15790 d38d1ca762b97e7eddc26efff512d99f 356 Gene3D G3DSA:2.40.160.20 43 180 2.1E-4 T 11-11-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AUP74_RS15790 d38d1ca762b97e7eddc26efff512d99f 356 Pfam PF13505 Outer membrane protein beta-barrel domain 9 180 2.6E-8 T 11-11-2016 IPR027385 Outer membrane protein beta-barrel AUP74_RS15790 d38d1ca762b97e7eddc26efff512d99f 356 SUPERFAMILY SSF103088 246 354 2.62E-38 T 11-11-2016 IPR006665 OmpA-like domain AUP74_RS15790 d38d1ca762b97e7eddc26efff512d99f 356 ProSitePatterns PS01068 OmpA-like domain. 287 331 - T 11-11-2016 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 AUP74_RS15790 d38d1ca762b97e7eddc26efff512d99f 356 PRINTS PR01021 OMPA domain signature 285 300 4.0E-14 T 11-11-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AUP74_RS15790 d38d1ca762b97e7eddc26efff512d99f 356 PRINTS PR01021 OMPA domain signature 255 277 4.0E-14 T 11-11-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AUP74_RS15790 d38d1ca762b97e7eddc26efff512d99f 356 PRINTS PR01021 OMPA domain signature 300 316 4.0E-14 T 11-11-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AUP74_RS15790 d38d1ca762b97e7eddc26efff512d99f 356 Pfam PF00691 OmpA family 255 349 7.1E-27 T 11-11-2016 IPR006665 OmpA-like domain AUP74_RS15790 d38d1ca762b97e7eddc26efff512d99f 356 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 300 317 8.6E-6 T 11-11-2016 AUP74_RS15790 d38d1ca762b97e7eddc26efff512d99f 356 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 318 337 8.6E-6 T 11-11-2016 AUP74_RS15790 d38d1ca762b97e7eddc26efff512d99f 356 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 338 356 8.6E-6 T 11-11-2016 AUP74_RS15790 d38d1ca762b97e7eddc26efff512d99f 356 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 242 269 8.6E-6 T 11-11-2016 AUP74_RS15790 d38d1ca762b97e7eddc26efff512d99f 356 SUPERFAMILY SSF103647 211 246 9.02E-8 T 11-11-2016 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 AUP74_RS05025 6ec4c5ef27a4a8250d67d93d17131683 170 Gene3D G3DSA:3.40.50.2000 3 159 1.6E-16 T 11-11-2016 AUP74_RS05025 6ec4c5ef27a4a8250d67d93d17131683 170 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 13 161 4.7E-7 T 11-11-2016 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 AUP74_RS05025 6ec4c5ef27a4a8250d67d93d17131683 170 SUPERFAMILY SSF53756 3 112 1.1E-8 T 11-11-2016 AUP74_RS04985 5f5b7ea88eb35f81bcde908d6c5600b2 283 Gene3D G3DSA:1.10.3680.10 146 281 1.6E-15 T 11-11-2016 IPR029024 TerB-like AUP74_RS04985 5f5b7ea88eb35f81bcde908d6c5600b2 283 SUPERFAMILY SSF158682 162 281 2.49E-16 T 11-11-2016 IPR029024 TerB-like AUP74_RS04985 5f5b7ea88eb35f81bcde908d6c5600b2 283 Pfam PF04391 Protein of unknown function (DUF533) 61 280 1.3E-35 T 11-11-2016 IPR007486 Inner membrane protein YebE AUP74_RS11965 7561574f86daa9105efd3ac9068bb124 335 Pfam PF10503 Esterase PHB depolymerase 42 184 1.8E-20 T 11-11-2016 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 AUP74_RS11965 7561574f86daa9105efd3ac9068bb124 335 SUPERFAMILY SSF53474 281 324 2.29E-22 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS11965 7561574f86daa9105efd3ac9068bb124 335 SUPERFAMILY SSF53474 135 250 2.29E-22 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS11965 7561574f86daa9105efd3ac9068bb124 335 SUPERFAMILY SSF53474 37 178 1.27E-11 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS11965 7561574f86daa9105efd3ac9068bb124 335 Gene3D G3DSA:3.40.50.1820 36 328 8.9E-32 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS11965 7561574f86daa9105efd3ac9068bb124 335 TIGRFAM TIGR01840 esterase_phb: esterase, PHB depolymerase family 41 249 1.7E-41 T 11-11-2016 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 AUP74_RS13935 117367cd48326e220486a96a626065bf 353 Pfam PF01565 FAD binding domain 12 139 6.6E-15 T 11-11-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AUP74_RS13935 117367cd48326e220486a96a626065bf 353 SUPERFAMILY SSF56176 12 176 5.14E-27 T 11-11-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 AUP74_RS13935 117367cd48326e220486a96a626065bf 353 Gene3D G3DSA:3.30.465.10 56 176 1.2E-19 T 11-11-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 AUP74_RS13935 117367cd48326e220486a96a626065bf 353 Gene3D G3DSA:1.10.45.10 324 340 1.3E-4 T 11-11-2016 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 AUP74_RS13935 117367cd48326e220486a96a626065bf 353 SUPERFAMILY SSF55103 161 219 4.03E-5 T 11-11-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 AUP74_RS13935 117367cd48326e220486a96a626065bf 353 SUPERFAMILY SSF55103 268 340 4.03E-5 T 11-11-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 AUP74_RS03215 a1b505258bf272899e9c8f76d7c5c869 449 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 58 373 1.8E-103 T 11-11-2016 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 AUP74_RS03215 a1b505258bf272899e9c8f76d7c5c869 449 SUPERFAMILY SSF50156 96 188 3.05E-20 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS03215 a1b505258bf272899e9c8f76d7c5c869 449 Gene3D G3DSA:3.30.750.44 54 111 4.7E-8 T 11-11-2016 AUP74_RS03215 a1b505258bf272899e9c8f76d7c5c869 449 SMART SM00228 105 176 9.5E-17 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS03215 a1b505258bf272899e9c8f76d7c5c869 449 Gene3D G3DSA:3.90.226.10 411 431 7.9E-65 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS03215 a1b505258bf272899e9c8f76d7c5c869 449 Gene3D G3DSA:3.90.226.10 187 370 7.9E-65 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS03215 a1b505258bf272899e9c8f76d7c5c869 449 Gene3D G3DSA:2.30.42.10 112 186 7.8E-28 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS03215 a1b505258bf272899e9c8f76d7c5c869 449 Pfam PF03572 Peptidase family S41 204 366 1.5E-55 T 11-11-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 AUP74_RS03215 a1b505258bf272899e9c8f76d7c5c869 449 Pfam PF13180 PDZ domain 105 185 1.5E-12 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS03215 a1b505258bf272899e9c8f76d7c5c869 449 SUPERFAMILY SSF52096 39 123 1.99E-79 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS03215 a1b505258bf272899e9c8f76d7c5c869 449 SUPERFAMILY SSF52096 197 370 1.99E-79 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS03215 a1b505258bf272899e9c8f76d7c5c869 449 SMART SM00245 178 368 1.2E-73 T 11-11-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 AUP74_RS14805 22ccae27de39937b2dbb089c35ba19e4 743 SUPERFAMILY SSF51735 8 178 1.57E-43 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS14805 22ccae27de39937b2dbb089c35ba19e4 743 Gene3D G3DSA:3.65.10.10 328 537 1.7E-61 T 11-11-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 AUP74_RS14805 22ccae27de39937b2dbb089c35ba19e4 743 ProSitePatterns PS00885 EPSP synthase signature 2. 647 665 - T 11-11-2016 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AUP74_RS14805 22ccae27de39937b2dbb089c35ba19e4 743 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 316 739 33.383 T 11-11-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AUP74_RS14805 22ccae27de39937b2dbb089c35ba19e4 743 Pfam PF02153 Prephenate dehydrogenase 21 280 7.9E-69 T 11-11-2016 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 AUP74_RS14805 22ccae27de39937b2dbb089c35ba19e4 743 SUPERFAMILY SSF55205 310 737 2.62E-129 T 11-11-2016 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 AUP74_RS14805 22ccae27de39937b2dbb089c35ba19e4 743 ProSitePatterns PS00104 EPSP synthase signature 1. 395 409 - T 11-11-2016 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AUP74_RS14805 22ccae27de39937b2dbb089c35ba19e4 743 Gene3D G3DSA:3.40.50.720 8 188 8.5E-32 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS14805 22ccae27de39937b2dbb089c35ba19e4 743 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 320 735 3.2E-123 T 11-11-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AUP74_RS14805 22ccae27de39937b2dbb089c35ba19e4 743 Gene3D G3DSA:3.65.10.10 538 737 2.2E-53 T 11-11-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 AUP74_RS14805 22ccae27de39937b2dbb089c35ba19e4 743 SUPERFAMILY SSF48179 185 290 4.65E-35 T 11-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AUP74_RS14805 22ccae27de39937b2dbb089c35ba19e4 743 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 314 731 3.1E-115 T 11-11-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 AUP74_RS01120 a682c7f28ac0caf52f8ea3ebff2fefbc 375 SUPERFAMILY SSF51246 309 370 7.46E-13 T 11-11-2016 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AUP74_RS01120 a682c7f28ac0caf52f8ea3ebff2fefbc 375 SUPERFAMILY SSF52440 4 102 5.18E-14 T 11-11-2016 IPR016185 Pre-ATP-grasp domain AUP74_RS01120 a682c7f28ac0caf52f8ea3ebff2fefbc 375 SUPERFAMILY SSF56059 103 305 1.57E-58 T 11-11-2016 AUP74_RS01120 a682c7f28ac0caf52f8ea3ebff2fefbc 375 Pfam PF02222 ATP-grasp domain 113 285 1.0E-49 T 11-11-2016 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type AUP74_RS01120 a682c7f28ac0caf52f8ea3ebff2fefbc 375 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 5 353 35.929 T 11-11-2016 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 AUP74_RS01120 a682c7f28ac0caf52f8ea3ebff2fefbc 375 Gene3D G3DSA:3.40.50.20 5 93 8.1E-17 T 11-11-2016 IPR016185 Pre-ATP-grasp domain AUP74_RS01120 a682c7f28ac0caf52f8ea3ebff2fefbc 375 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 6 357 2.6E-104 T 11-11-2016 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 AUP74_RS01120 a682c7f28ac0caf52f8ea3ebff2fefbc 375 Gene3D G3DSA:3.30.470.20 143 367 1.0E-70 T 11-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 AUP74_RS10480 6f1ecb95004343c0b4398e2c6eb5b0f3 664 Pfam PF01266 FAD dependent oxidoreductase 269 632 5.0E-43 T 11-11-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AUP74_RS10480 6f1ecb95004343c0b4398e2c6eb5b0f3 664 Gene3D G3DSA:3.40.50.720 241 282 2.6E-4 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS10480 6f1ecb95004343c0b4398e2c6eb5b0f3 664 Pfam PF05430 S-adenosyl-L-methionine-dependent methyltransferase 114 240 2.1E-35 T 11-11-2016 IPR008471 MnmC-like methyltransferase GO:0016645|GO:0055114 AUP74_RS10480 6f1ecb95004343c0b4398e2c6eb5b0f3 664 SUPERFAMILY SSF51905 568 654 3.43E-38 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS10480 6f1ecb95004343c0b4398e2c6eb5b0f3 664 SUPERFAMILY SSF51905 269 479 3.43E-38 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS10480 6f1ecb95004343c0b4398e2c6eb5b0f3 664 Gene3D G3DSA:3.50.50.60 283 338 2.6E-30 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS10480 6f1ecb95004343c0b4398e2c6eb5b0f3 664 Gene3D G3DSA:3.50.50.60 398 478 2.6E-30 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS10480 6f1ecb95004343c0b4398e2c6eb5b0f3 664 Gene3D G3DSA:3.50.50.60 568 655 2.6E-30 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS10480 6f1ecb95004343c0b4398e2c6eb5b0f3 664 Hamap MF_01102 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC [mnmC]. 6 656 26.564 T 11-11-2016 IPR023032 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC GO:0004808|GO:0008033|GO:0008168|GO:0016645|GO:0055114 AUP74_RS10480 6f1ecb95004343c0b4398e2c6eb5b0f3 664 SUPERFAMILY SSF54373 477 551 7.46E-5 T 11-11-2016 AUP74_RS10480 6f1ecb95004343c0b4398e2c6eb5b0f3 664 TIGRFAM TIGR03197 MnmC_Cterm: tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain 268 660 4.3E-125 T 11-11-2016 IPR017610 tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal GO:0008168|GO:0016645|GO:0055114 AUP74_RS10480 6f1ecb95004343c0b4398e2c6eb5b0f3 664 Gene3D G3DSA:3.40.50.150 10 240 1.4E-83 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS15595 d9e1007ab394eeab5522991b8b769e54 259 PIRSF PIRSF000456 1 259 9.7E-101 T 11-11-2016 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 AUP74_RS15595 d9e1007ab394eeab5522991b8b769e54 259 SUPERFAMILY SSF51161 3 259 8.74E-77 T 11-11-2016 IPR011004 Trimeric LpxA-like AUP74_RS15595 d9e1007ab394eeab5522991b8b769e54 259 Gene3D G3DSA:2.160.10.10 3 190 4.1E-48 T 11-11-2016 AUP74_RS15595 d9e1007ab394eeab5522991b8b769e54 259 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 106 139 5.9E-7 T 11-11-2016 IPR001451 Hexapeptide repeat AUP74_RS15595 d9e1007ab394eeab5522991b8b769e54 259 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 14 49 5.7E-10 T 11-11-2016 IPR001451 Hexapeptide repeat AUP74_RS15595 d9e1007ab394eeab5522991b8b769e54 259 Hamap MF_00387 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [lpxA]. 2 259 43.301 T 11-11-2016 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 AUP74_RS15595 d9e1007ab394eeab5522991b8b769e54 259 Gene3D G3DSA:1.20.1180.10 194 259 1.5E-22 T 11-11-2016 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 AUP74_RS15595 d9e1007ab394eeab5522991b8b769e54 259 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 177 258 3.9E-27 T 11-11-2016 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 AUP74_RS15595 d9e1007ab394eeab5522991b8b769e54 259 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 5 258 4.8E-96 T 11-11-2016 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 AUP74_RS01800 c611b3d7245118619b2da2fa22e2905c 488 SUPERFAMILY SSF53067 5 124 1.13E-32 T 11-11-2016 AUP74_RS01800 c611b3d7245118619b2da2fa22e2905c 488 Gene3D G3DSA:3.30.420.40 2 124 1.1E-39 T 11-11-2016 AUP74_RS01800 c611b3d7245118619b2da2fa22e2905c 488 PIRSF PIRSF001267 1 488 8.1E-146 T 11-11-2016 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 AUP74_RS01800 c611b3d7245118619b2da2fa22e2905c 488 SUPERFAMILY SSF109604 305 483 3.14E-32 T 11-11-2016 AUP74_RS01800 c611b3d7245118619b2da2fa22e2905c 488 SUPERFAMILY SSF53067 133 301 1.79E-32 T 11-11-2016 AUP74_RS01800 c611b3d7245118619b2da2fa22e2905c 488 Pfam PF02541 Ppx/GppA phosphatase family 24 298 3.2E-65 T 11-11-2016 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 AUP74_RS01800 c611b3d7245118619b2da2fa22e2905c 488 Gene3D G3DSA:3.30.420.150 131 300 2.8E-40 T 11-11-2016 AUP74_RS05950 6d9ee22cb87f36581c82504630650f80 76 Gene3D G3DSA:4.10.640.10 8 74 1.4E-32 T 11-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS05950 6d9ee22cb87f36581c82504630650f80 76 Pfam PF01084 Ribosomal protein S18 19 68 1.7E-24 T 11-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS05950 6d9ee22cb87f36581c82504630650f80 76 SUPERFAMILY SSF46911 3 74 4.97E-29 T 11-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS05950 6d9ee22cb87f36581c82504630650f80 76 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 2 73 20.94 T 11-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS05950 6d9ee22cb87f36581c82504630650f80 76 PRINTS PR00974 Ribosomal protein S18 family signature 28 38 3.9E-18 T 11-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS05950 6d9ee22cb87f36581c82504630650f80 76 PRINTS PR00974 Ribosomal protein S18 family signature 60 70 3.9E-18 T 11-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS05950 6d9ee22cb87f36581c82504630650f80 76 PRINTS PR00974 Ribosomal protein S18 family signature 38 45 3.9E-18 T 11-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS05950 6d9ee22cb87f36581c82504630650f80 76 PRINTS PR00974 Ribosomal protein S18 family signature 46 60 3.9E-18 T 11-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS05950 6d9ee22cb87f36581c82504630650f80 76 TIGRFAM TIGR00165 S18: ribosomal protein bS18 4 72 3.8E-37 T 11-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS05950 6d9ee22cb87f36581c82504630650f80 76 ProSitePatterns PS00057 Ribosomal protein S18 signature. 21 44 - T 11-11-2016 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS05950 6d9ee22cb87f36581c82504630650f80 76 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 21 71 1.0E-21 T 11-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS03665 02714c3bf90ddf9c03507fdbcfc40bf7 167 Pfam PF02308 MgtC family 15 136 2.5E-27 T 11-11-2016 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 AUP74_RS03665 02714c3bf90ddf9c03507fdbcfc40bf7 167 PRINTS PR01837 MgtC/SapB protein signature 18 37 1.5E-32 T 11-11-2016 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 AUP74_RS03665 02714c3bf90ddf9c03507fdbcfc40bf7 167 PRINTS PR01837 MgtC/SapB protein signature 90 114 1.5E-32 T 11-11-2016 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 AUP74_RS03665 02714c3bf90ddf9c03507fdbcfc40bf7 167 PRINTS PR01837 MgtC/SapB protein signature 63 85 1.5E-32 T 11-11-2016 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 AUP74_RS03665 02714c3bf90ddf9c03507fdbcfc40bf7 167 PRINTS PR01837 MgtC/SapB protein signature 37 55 1.5E-32 T 11-11-2016 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 AUP74_RS13960 c5d62f9379129fe20bb7436a38cd2129 640 Gene3D G3DSA:3.90.1150.10 448 519 1.1E-8 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS13960 c5d62f9379129fe20bb7436a38cd2129 640 SUPERFAMILY SSF53383 130 520 8.85E-86 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase AUP74_RS13960 c5d62f9379129fe20bb7436a38cd2129 640 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 563 593 2.4E-7 T 11-11-2016 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 AUP74_RS13960 c5d62f9379129fe20bb7436a38cd2129 640 Gene3D G3DSA:3.40.640.10 130 414 8.3E-105 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AUP74_RS13960 c5d62f9379129fe20bb7436a38cd2129 640 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 351 365 - T 11-11-2016 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 AUP74_RS13960 c5d62f9379129fe20bb7436a38cd2129 640 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 130 506 9.8E-97 T 11-11-2016 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 AUP74_RS13960 c5d62f9379129fe20bb7436a38cd2129 640 Gene3D G3DSA:3.90.100.10 520 607 1.5E-17 T 11-11-2016 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 AUP74_RS10425 c5047a2620ff9170703b859705e6c3ec 593 SUPERFAMILY SSF89000 300 468 1.96E-52 T 11-11-2016 AUP74_RS10425 c5047a2620ff9170703b859705e6c3ec 593 Pfam PF00364 Biotin-requiring enzyme 527 592 1.2E-18 T 11-11-2016 IPR000089 Biotin/lipoyl attachment AUP74_RS10425 c5047a2620ff9170703b859705e6c3ec 593 SUPERFAMILY SSF51569 5 302 1.74E-90 T 11-11-2016 AUP74_RS10425 c5047a2620ff9170703b859705e6c3ec 593 SUPERFAMILY SSF51230 519 592 1.96E-21 T 11-11-2016 IPR011053 Single hybrid motif AUP74_RS10425 c5047a2620ff9170703b859705e6c3ec 593 Pfam PF00682 HMGL-like 10 273 2.6E-56 T 11-11-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 AUP74_RS10425 c5047a2620ff9170703b859705e6c3ec 593 Pfam PF02436 Conserved carboxylase domain 295 494 1.1E-60 T 11-11-2016 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 AUP74_RS10425 c5047a2620ff9170703b859705e6c3ec 593 Gene3D G3DSA:2.40.50.100 522 592 6.6E-26 T 11-11-2016 AUP74_RS10425 c5047a2620ff9170703b859705e6c3ec 593 Gene3D G3DSA:3.20.20.70 5 285 1.7E-116 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS10425 c5047a2620ff9170703b859705e6c3ec 593 TIGRFAM TIGR01108 oadA: oxaloacetate decarboxylase alpha subunit 10 589 2.1E-272 T 11-11-2016 IPR005776 Oxaloacetate decarboxylase, alpha subunit GO:0006814|GO:0008948 AUP74_RS10425 c5047a2620ff9170703b859705e6c3ec 593 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 549 566 - T 11-11-2016 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AUP74_RS12210 c9dedf1531a839a0207c9b4f64788be8 344 SUPERFAMILY SSF52540 53 188 1.06E-11 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS12210 c9dedf1531a839a0207c9b4f64788be8 344 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 23 337 1.1E-100 T 11-11-2016 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 AUP74_RS12210 c9dedf1531a839a0207c9b4f64788be8 344 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 6 338 37.102 T 11-11-2016 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 AUP74_RS12210 c9dedf1531a839a0207c9b4f64788be8 344 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 24 327 2.4E-69 T 11-11-2016 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 AUP74_RS12210 c9dedf1531a839a0207c9b4f64788be8 344 Gene3D G3DSA:3.40.50.300 52 151 1.9E-5 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05495 b4def212343b342d39e255969dc989bd 231 PIRSF PIRSF004848 1 231 1.9E-75 T 11-11-2016 IPR011078 Uncharacterised protein family UPF0001 AUP74_RS05495 b4def212343b342d39e255969dc989bd 231 SUPERFAMILY SSF51419 2 228 1.57E-84 T 11-11-2016 IPR029066 PLP-binding barrel AUP74_RS05495 b4def212343b342d39e255969dc989bd 231 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 78 92 - T 11-11-2016 IPR011078 Uncharacterised protein family UPF0001 AUP74_RS05495 b4def212343b342d39e255969dc989bd 231 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 5 230 5.1E-86 T 11-11-2016 IPR011078 Uncharacterised protein family UPF0001 AUP74_RS05495 b4def212343b342d39e255969dc989bd 231 Pfam PF01168 Alanine racemase, N-terminal domain 10 230 3.5E-29 T 11-11-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AUP74_RS05495 b4def212343b342d39e255969dc989bd 231 Gene3D G3DSA:3.20.20.10 2 231 7.7E-98 T 11-11-2016 IPR029066 PLP-binding barrel AUP74_RS03980 cd24104af0b114c175b02d4c5fbdf456 271 SUPERFAMILY SSF57716 219 270 4.89E-16 T 11-11-2016 AUP74_RS03980 cd24104af0b114c175b02d4c5fbdf456 271 SUPERFAMILY SSF81624 2 136 1.24E-40 T 11-11-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 AUP74_RS03980 cd24104af0b114c175b02d4c5fbdf456 271 Pfam PF06827 Zinc finger found in FPG and IleRS 243 270 1.1E-8 T 11-11-2016 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 AUP74_RS03980 cd24104af0b114c175b02d4c5fbdf456 271 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 270 2.1E-92 T 11-11-2016 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 AUP74_RS03980 cd24104af0b114c175b02d4c5fbdf456 271 ProSitePatterns PS01242 Zinc finger FPG-type signature. 246 270 - T 11-11-2016 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 AUP74_RS03980 cd24104af0b114c175b02d4c5fbdf456 271 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 131 220 9.7E-24 T 11-11-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 AUP74_RS03980 cd24104af0b114c175b02d4c5fbdf456 271 Gene3D G3DSA:3.20.190.10 2 131 3.4E-38 T 11-11-2016 AUP74_RS03980 cd24104af0b114c175b02d4c5fbdf456 271 SUPERFAMILY SSF46946 132 223 2.88E-29 T 11-11-2016 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 AUP74_RS03980 cd24104af0b114c175b02d4c5fbdf456 271 SMART SM01232 131 223 1.1E-48 T 11-11-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 AUP74_RS03980 cd24104af0b114c175b02d4c5fbdf456 271 Gene3D G3DSA:1.10.8.50 132 271 1.2E-48 T 11-11-2016 AUP74_RS03980 cd24104af0b114c175b02d4c5fbdf456 271 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 114 5.2E-32 T 11-11-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 AUP74_RS03980 cd24104af0b114c175b02d4c5fbdf456 271 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 271 43.958 T 11-11-2016 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 AUP74_RS03980 cd24104af0b114c175b02d4c5fbdf456 271 SMART SM00898 2 116 1.3E-49 T 11-11-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 AUP74_RS14340 7877be02967042a7bbe1677040d962b4 880 SUPERFAMILY SSF56935 42 279 4.76E-99 T 11-11-2016 AUP74_RS14340 7877be02967042a7bbe1677040d962b4 880 SUPERFAMILY SSF56935 335 712 4.76E-99 T 11-11-2016 AUP74_RS14340 7877be02967042a7bbe1677040d962b4 880 SUPERFAMILY SSF56935 762 880 4.76E-99 T 11-11-2016 AUP74_RS14340 7877be02967042a7bbe1677040d962b4 880 Gene3D G3DSA:2.40.170.20 175 266 9.2E-69 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS14340 7877be02967042a7bbe1677040d962b4 880 Gene3D G3DSA:2.40.170.20 761 880 9.2E-69 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS14340 7877be02967042a7bbe1677040d962b4 880 Gene3D G3DSA:2.40.170.20 312 711 9.2E-69 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS14340 7877be02967042a7bbe1677040d962b4 880 Gene3D G3DSA:2.170.130.10 41 173 2.4E-32 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS14340 7877be02967042a7bbe1677040d962b4 880 Pfam PF07715 TonB-dependent Receptor Plug Domain 57 164 1.7E-19 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS01735 279c85f3a0bf4bb179a3bc5a2e40d59c 747 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 141 739 3.0E-187 T 11-11-2016 AUP74_RS01735 279c85f3a0bf4bb179a3bc5a2e40d59c 747 Gene3D G3DSA:3.40.1110.10 453 556 6.6E-21 T 11-11-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 AUP74_RS01735 279c85f3a0bf4bb179a3bc5a2e40d59c 747 Gene3D G3DSA:2.70.150.10 174 327 2.1E-34 T 11-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 AUP74_RS01735 279c85f3a0bf4bb179a3bc5a2e40d59c 747 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 159 738 2.6E-193 T 11-11-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AUP74_RS01735 279c85f3a0bf4bb179a3bc5a2e40d59c 747 ProSitePatterns PS01047 Heavy-metal-associated domain. 10 39 - T 11-11-2016 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 AUP74_RS01735 279c85f3a0bf4bb179a3bc5a2e40d59c 747 SUPERFAMILY SSF56784 487 735 7.73E-57 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS01735 279c85f3a0bf4bb179a3bc5a2e40d59c 747 SUPERFAMILY SSF56784 426 446 7.73E-57 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS01735 279c85f3a0bf4bb179a3bc5a2e40d59c 747 SUPERFAMILY SSF55008 5 71 4.06E-17 T 11-11-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 AUP74_RS01735 279c85f3a0bf4bb179a3bc5a2e40d59c 747 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 629 648 1.2E-28 T 11-11-2016 AUP74_RS01735 279c85f3a0bf4bb179a3bc5a2e40d59c 747 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 576 586 1.2E-28 T 11-11-2016 AUP74_RS01735 279c85f3a0bf4bb179a3bc5a2e40d59c 747 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 428 442 1.2E-28 T 11-11-2016 AUP74_RS01735 279c85f3a0bf4bb179a3bc5a2e40d59c 747 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 652 664 1.2E-28 T 11-11-2016 AUP74_RS01735 279c85f3a0bf4bb179a3bc5a2e40d59c 747 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 554 565 1.2E-28 T 11-11-2016 AUP74_RS01735 279c85f3a0bf4bb179a3bc5a2e40d59c 747 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 276 290 1.2E-28 T 11-11-2016 AUP74_RS01735 279c85f3a0bf4bb179a3bc5a2e40d59c 747 SUPERFAMILY SSF81665 678 698 5.36E-9 T 11-11-2016 AUP74_RS01735 279c85f3a0bf4bb179a3bc5a2e40d59c 747 SUPERFAMILY SSF81665 327 422 5.36E-9 T 11-11-2016 AUP74_RS01735 279c85f3a0bf4bb179a3bc5a2e40d59c 747 SUPERFAMILY SSF81665 192 230 5.36E-9 T 11-11-2016 AUP74_RS01735 279c85f3a0bf4bb179a3bc5a2e40d59c 747 Pfam PF00403 Heavy-metal-associated domain 7 64 3.4E-14 T 11-11-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 AUP74_RS01735 279c85f3a0bf4bb179a3bc5a2e40d59c 747 Pfam PF00122 E1-E2 ATPase 197 419 7.7E-67 T 11-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 AUP74_RS01735 279c85f3a0bf4bb179a3bc5a2e40d59c 747 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 198 706 1.3E-88 T 11-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AUP74_RS01735 279c85f3a0bf4bb179a3bc5a2e40d59c 747 PRINTS PR00943 Copper-transporting ATPase signature 606 623 1.5E-7 T 11-11-2016 AUP74_RS01735 279c85f3a0bf4bb179a3bc5a2e40d59c 747 PRINTS PR00943 Copper-transporting ATPase signature 349 363 1.5E-7 T 11-11-2016 AUP74_RS01735 279c85f3a0bf4bb179a3bc5a2e40d59c 747 PRINTS PR00943 Copper-transporting ATPase signature 144 163 1.5E-7 T 11-11-2016 AUP74_RS01735 279c85f3a0bf4bb179a3bc5a2e40d59c 747 PRINTS PR00943 Copper-transporting ATPase signature 411 426 1.5E-7 T 11-11-2016 AUP74_RS01735 279c85f3a0bf4bb179a3bc5a2e40d59c 747 SUPERFAMILY SSF81653 229 326 2.22E-30 T 11-11-2016 AUP74_RS01735 279c85f3a0bf4bb179a3bc5a2e40d59c 747 Gene3D G3DSA:3.40.50.1000 557 698 1.3E-56 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS01735 279c85f3a0bf4bb179a3bc5a2e40d59c 747 Gene3D G3DSA:3.40.50.1000 399 444 1.3E-56 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS01735 279c85f3a0bf4bb179a3bc5a2e40d59c 747 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 430 436 - T 11-11-2016 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 AUP74_RS01735 279c85f3a0bf4bb179a3bc5a2e40d59c 747 Gene3D G3DSA:3.30.70.100 5 69 8.9E-21 T 11-11-2016 AUP74_RS01735 279c85f3a0bf4bb179a3bc5a2e40d59c 747 Pfam PF00702 haloacid dehalogenase-like hydrolase 425 642 2.4E-42 T 11-11-2016 AUP74_RS09735 d639c3db7cced52abc746f92aeaf674a 239 Gene3D G3DSA:3.40.50.300 4 224 1.1E-62 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS09735 d639c3db7cced52abc746f92aeaf674a 239 SMART SM00382 33 229 6.5E-13 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS09735 d639c3db7cced52abc746f92aeaf674a 239 Pfam PF00005 ABC transporter 24 173 5.4E-32 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AUP74_RS09735 d639c3db7cced52abc746f92aeaf674a 239 SUPERFAMILY SSF52540 4 225 6.65E-60 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS09735 d639c3db7cced52abc746f92aeaf674a 239 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AUP74_RS11585 277fe6f11be33baa437864895b7a89b7 557 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 27 553 2.3E-240 T 11-11-2016 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AUP74_RS11585 277fe6f11be33baa437864895b7a89b7 557 Gene3D G3DSA:3.90.800.10 100 208 5.0E-49 T 11-11-2016 AUP74_RS11585 277fe6f11be33baa437864895b7a89b7 557 Gene3D G3DSA:2.40.240.10 347 461 5.2E-44 T 11-11-2016 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AUP74_RS11585 277fe6f11be33baa437864895b7a89b7 557 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 33 44 - T 11-11-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS11585 277fe6f11be33baa437864895b7a89b7 557 Gene3D G3DSA:3.40.50.620 211 261 3.0E-42 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS11585 277fe6f11be33baa437864895b7a89b7 557 Gene3D G3DSA:3.40.50.620 26 95 3.0E-42 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS11585 277fe6f11be33baa437864895b7a89b7 557 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 1 551 51.75 T 11-11-2016 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 AUP74_RS11585 277fe6f11be33baa437864895b7a89b7 557 Gene3D G3DSA:1.10.1160.10 262 337 1.4E-38 T 11-11-2016 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 AUP74_RS11585 277fe6f11be33baa437864895b7a89b7 557 SUPERFAMILY SSF52374 26 345 3.66E-99 T 11-11-2016 AUP74_RS11585 277fe6f11be33baa437864895b7a89b7 557 PRINTS PR00987 Glutamyl-tRNA synthetase signature 30 42 9.6E-9 T 11-11-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 AUP74_RS11585 277fe6f11be33baa437864895b7a89b7 557 PRINTS PR00987 Glutamyl-tRNA synthetase signature 44 55 9.6E-9 T 11-11-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 AUP74_RS11585 277fe6f11be33baa437864895b7a89b7 557 PRINTS PR00987 Glutamyl-tRNA synthetase signature 59 72 9.6E-9 T 11-11-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 AUP74_RS11585 277fe6f11be33baa437864895b7a89b7 557 PRINTS PR00987 Glutamyl-tRNA synthetase signature 209 219 9.6E-9 T 11-11-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 AUP74_RS11585 277fe6f11be33baa437864895b7a89b7 557 SUPERFAMILY SSF50715 339 550 1.36E-66 T 11-11-2016 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AUP74_RS11585 277fe6f11be33baa437864895b7a89b7 557 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 26 336 3.8E-115 T 11-11-2016 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 AUP74_RS11585 277fe6f11be33baa437864895b7a89b7 557 Gene3D G3DSA:2.40.240.10 462 549 2.0E-27 T 11-11-2016 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AUP74_RS11585 277fe6f11be33baa437864895b7a89b7 557 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 339 530 2.6E-55 T 11-11-2016 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AUP74_RS14320 86ffb264b84426bb637c75e5e2402f79 79 SUPERFAMILY SSF158997 5 55 4.71E-13 T 11-11-2016 AUP74_RS14320 86ffb264b84426bb637c75e5e2402f79 79 Gene3D G3DSA:2.20.25.10 9 55 4.0E-10 T 11-11-2016 AUP74_RS07525 4082ae86fe66e2921d1678571c095fcf 295 SUPERFAMILY SSF52833 153 277 1.18E-6 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS07525 4082ae86fe66e2921d1678571c095fcf 295 Gene3D G3DSA:3.40.30.10 155 274 3.2E-6 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS03125 68125fbe0dc70cfb62764cb2b63f582c 508 ProSitePatterns PS00455 Putative AMP-binding domain signature. 165 176 - T 11-11-2016 IPR020845 AMP-binding, conserved site AUP74_RS03125 68125fbe0dc70cfb62764cb2b63f582c 508 SUPERFAMILY SSF56801 4 506 1.28E-150 T 11-11-2016 AUP74_RS03125 68125fbe0dc70cfb62764cb2b63f582c 508 Pfam PF00501 AMP-binding enzyme 8 409 1.7E-98 T 11-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 AUP74_RS03125 68125fbe0dc70cfb62764cb2b63f582c 508 Gene3D G3DSA:3.40.50.980 170 324 1.1E-38 T 11-11-2016 AUP74_RS03125 68125fbe0dc70cfb62764cb2b63f582c 508 Pfam PF13193 AMP-binding enzyme C-terminal domain 419 495 8.5E-20 T 11-11-2016 IPR025110 AMP-binding enzyme C-terminal domain AUP74_RS03125 68125fbe0dc70cfb62764cb2b63f582c 508 Gene3D G3DSA:2.30.38.10 327 401 5.1E-30 T 11-11-2016 AUP74_RS03125 68125fbe0dc70cfb62764cb2b63f582c 508 Gene3D G3DSA:3.40.50.980 4 169 5.4E-35 T 11-11-2016 AUP74_RS03125 68125fbe0dc70cfb62764cb2b63f582c 508 Gene3D G3DSA:3.30.300.30 405 504 5.9E-32 T 11-11-2016 AUP74_RS10665 2df2e196bd94b027e945fe17fe437df4 106 SUPERFAMILY SSF103481 5 104 9.68E-18 T 11-11-2016 AUP74_RS10665 2df2e196bd94b027e945fe17fe437df4 106 Pfam PF00893 Small Multidrug Resistance protein 1 92 9.3E-30 T 11-11-2016 IPR000390 Small multidrug resistance protein family GO:0016021 AUP74_RS15045 ec21895eefeadb513917b4340c8dd878 649 Pfam PF00773 RNB domain 196 521 3.0E-73 T 11-11-2016 AUP74_RS15045 ec21895eefeadb513917b4340c8dd878 649 Pfam PF00575 S1 RNA binding domain 561 642 1.8E-10 T 11-11-2016 IPR003029 S1 domain GO:0003676 AUP74_RS15045 ec21895eefeadb513917b4340c8dd878 649 Gene3D G3DSA:2.40.50.140 548 642 1.1E-10 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS15045 ec21895eefeadb513917b4340c8dd878 649 SMART SM00955 196 522 4.1E-85 T 11-11-2016 AUP74_RS15045 ec21895eefeadb513917b4340c8dd878 649 SUPERFAMILY SSF50249 157 561 1.2E-93 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS15045 ec21895eefeadb513917b4340c8dd878 649 SUPERFAMILY SSF50249 10 83 6.09E-11 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS15045 ec21895eefeadb513917b4340c8dd878 649 SUPERFAMILY SSF50249 87 171 4.71E-16 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS15045 ec21895eefeadb513917b4340c8dd878 649 SUPERFAMILY SSF50249 564 641 4.55E-13 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS15045 ec21895eefeadb513917b4340c8dd878 649 SMART SM00316 19 79 1.6 T 11-11-2016 IPR022967 RNA-binding domain, S1 AUP74_RS15045 ec21895eefeadb513917b4340c8dd878 649 SMART SM00316 562 643 8.2E-7 T 11-11-2016 IPR022967 RNA-binding domain, S1 AUP74_RS15045 ec21895eefeadb513917b4340c8dd878 649 Pfam PF08206 Ribonuclease B OB domain 26 73 8.8E-8 T 11-11-2016 IPR013223 Ribonuclease B, N-terminal OB domain AUP74_RS15045 ec21895eefeadb513917b4340c8dd878 649 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 10 642 8.4E-137 T 11-11-2016 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 AUP74_RS03295 ca384ea33640f619ac94d3be7ff714c9 280 SMART SM00470 28 122 1.8E-7 T 11-11-2016 IPR003115 ParB/Sulfiredoxin AUP74_RS03295 ca384ea33640f619ac94d3be7ff714c9 280 Gene3D G3DSA:3.90.1530.10 29 108 1.7E-10 T 11-11-2016 AUP74_RS03295 ca384ea33640f619ac94d3be7ff714c9 280 Pfam PF02195 ParB-like nuclease domain 30 119 2.9E-9 T 11-11-2016 IPR003115 ParB/Sulfiredoxin AUP74_RS03295 ca384ea33640f619ac94d3be7ff714c9 280 SUPERFAMILY SSF110849 47 108 1.12E-11 T 11-11-2016 IPR003115 ParB/Sulfiredoxin AUP74_RS15930 156b8c9cebfe59af11c38043930128c2 176 Gene3D G3DSA:1.20.144.10 8 170 5.4E-32 T 11-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase AUP74_RS15930 156b8c9cebfe59af11c38043930128c2 176 Pfam PF01569 PAP2 superfamily 66 171 1.1E-17 T 11-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase AUP74_RS15930 156b8c9cebfe59af11c38043930128c2 176 SMART SM00014 66 172 6.0E-13 T 11-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase AUP74_RS15930 156b8c9cebfe59af11c38043930128c2 176 SUPERFAMILY SSF48317 7 171 8.24E-31 T 11-11-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase AUP74_RS05975 6e276aa291b3b4035f094c853e35c8b4 295 Pfam PF00491 Arginase family 27 283 3.0E-63 T 11-11-2016 IPR006035 Ureohydrolase GO:0046872 AUP74_RS05975 6e276aa291b3b4035f094c853e35c8b4 295 PIRSF PIRSF036979 9 290 2.3E-54 T 11-11-2016 IPR006035 Ureohydrolase GO:0046872 AUP74_RS05975 6e276aa291b3b4035f094c853e35c8b4 295 TIGRFAM TIGR01230 agmatinase: agmatinase 17 284 3.4E-70 T 11-11-2016 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 AUP74_RS05975 6e276aa291b3b4035f094c853e35c8b4 295 SUPERFAMILY SSF52768 18 287 1.3E-65 T 11-11-2016 AUP74_RS05975 6e276aa291b3b4035f094c853e35c8b4 295 ProSitePatterns PS01053 Arginase family signature. 214 235 - T 11-11-2016 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 AUP74_RS05975 6e276aa291b3b4035f094c853e35c8b4 295 Gene3D G3DSA:3.40.800.10 17 288 2.9E-62 T 11-11-2016 IPR023696 Ureohydrolase domain AUP74_RS01525 7610cd6300cfff99c0f31a81dea637ee 211 SUPERFAMILY SSF50630 97 198 9.76E-18 T 11-11-2016 IPR021109 Aspartic peptidase domain AUP74_RS01525 7610cd6300cfff99c0f31a81dea637ee 211 Pfam PF13975 gag-polyprotein putative aspartyl protease 108 195 4.0E-23 T 11-11-2016 AUP74_RS01525 7610cd6300cfff99c0f31a81dea637ee 211 TIGRFAM TIGR02281 clan_AA_DTGA: clan AA aspartic protease, TIGR02281 family 92 208 3.3E-33 T 11-11-2016 IPR011969 Clan AA aspartic peptidase, C-terminal AUP74_RS08535 cb0a41288442f3d60587854fafcaf3b4 342 SUPERFAMILY SSF49899 44 316 4.88E-83 T 11-11-2016 IPR013320 Concanavalin A-like lectin/glucanase domain AUP74_RS08535 cb0a41288442f3d60587854fafcaf3b4 342 Pfam PF00722 Glycosyl hydrolases family 16 85 310 1.7E-29 T 11-11-2016 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 AUP74_RS08535 cb0a41288442f3d60587854fafcaf3b4 342 Gene3D G3DSA:2.60.120.200 40 314 5.3E-90 T 11-11-2016 IPR013320 Concanavalin A-like lectin/glucanase domain AUP74_RS08675 ae3f6aeddf176d6f2f77be1357acd473 469 Gene3D G3DSA:3.90.550.10 2 270 5.5E-103 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases AUP74_RS08675 ae3f6aeddf176d6f2f77be1357acd473 469 Pfam PF01050 Mannose-6-phosphate isomerase 314 464 2.2E-76 T 11-11-2016 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 AUP74_RS08675 ae3f6aeddf176d6f2f77be1357acd473 469 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 2 467 5.1E-234 T 11-11-2016 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 AUP74_RS08675 ae3f6aeddf176d6f2f77be1357acd473 469 Pfam PF00483 Nucleotidyl transferase 4 285 9.6E-71 T 11-11-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 AUP74_RS08675 ae3f6aeddf176d6f2f77be1357acd473 469 SUPERFAMILY SSF53448 2 280 8.45E-76 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases AUP74_RS08675 ae3f6aeddf176d6f2f77be1357acd473 469 SUPERFAMILY SSF51182 184 468 1.39E-95 T 11-11-2016 IPR011051 RmlC-like cupin domain AUP74_RS08675 ae3f6aeddf176d6f2f77be1357acd473 469 Gene3D G3DSA:2.60.120.10 356 468 2.0E-50 T 11-11-2016 IPR014710 RmlC-like jelly roll fold AUP74_RS11265 458c20719071eddca799b006a4f97ba7 270 Pfam PF00293 NUDIX domain 144 247 4.2E-18 T 11-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 AUP74_RS11265 458c20719071eddca799b006a4f97ba7 270 SUPERFAMILY SSF55811 20 109 4.46E-10 T 11-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 AUP74_RS11265 458c20719071eddca799b006a4f97ba7 270 Gene3D G3DSA:3.90.79.10 103 251 2.6E-40 T 11-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 AUP74_RS11265 458c20719071eddca799b006a4f97ba7 270 PRINTS PR00502 NUDIX hydrolase family signature 181 196 9.2E-5 T 11-11-2016 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AUP74_RS11265 458c20719071eddca799b006a4f97ba7 270 PRINTS PR00502 NUDIX hydrolase family signature 167 181 9.2E-5 T 11-11-2016 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AUP74_RS11265 458c20719071eddca799b006a4f97ba7 270 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 107 137 1.3E-5 T 11-11-2016 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381 AUP74_RS11265 458c20719071eddca799b006a4f97ba7 270 Pfam PF09296 NADH pyrophosphatase-like rudimentary NUDIX domain 22 104 1.1E-6 T 11-11-2016 IPR015375 NADH pyrophosphatase-like, N-terminal GO:0016787 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381 AUP74_RS11265 458c20719071eddca799b006a4f97ba7 270 SUPERFAMILY SSF55811 92 253 4.74E-39 T 11-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 AUP74_RS11265 458c20719071eddca799b006a4f97ba7 270 ProSitePatterns PS00893 Nudix box signature. 172 193 - T 11-11-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AUP74_RS10185 47c7873c43bdbe4e08c36dd182542f4f 152 SUPERFAMILY SSF54637 9 148 2.49E-33 T 11-11-2016 IPR029069 HotDog domain AUP74_RS10185 47c7873c43bdbe4e08c36dd182542f4f 152 Pfam PF01575 MaoC like domain 14 116 4.5E-23 T 11-11-2016 IPR002539 MaoC-like domain AUP74_RS10185 47c7873c43bdbe4e08c36dd182542f4f 152 Gene3D G3DSA:3.10.129.10 14 149 6.1E-31 T 11-11-2016 IPR029069 HotDog domain AUP74_RS03840 ac21610bb3b43069fd05ddf750ad9f37 728 SMART SM00490 488 585 4.4E-6 T 11-11-2016 IPR001650 Helicase, C-terminal AUP74_RS03840 ac21610bb3b43069fd05ddf750ad9f37 728 TIGRFAM TIGR00595 priA: primosomal protein N' 216 723 1.5E-164 T 11-11-2016 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 AUP74_RS03840 ac21610bb3b43069fd05ddf750ad9f37 728 SMART SM00487 192 388 2.0E-19 T 11-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain AUP74_RS03840 ac21610bb3b43069fd05ddf750ad9f37 728 SUPERFAMILY SSF52540 401 430 1.35E-16 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03840 ac21610bb3b43069fd05ddf750ad9f37 728 SUPERFAMILY SSF52540 491 605 1.35E-16 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03840 ac21610bb3b43069fd05ddf750ad9f37 728 Gene3D G3DSA:3.40.50.300 194 376 6.2E-36 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03840 ac21610bb3b43069fd05ddf750ad9f37 728 Pfam PF00271 Helicase conserved C-terminal domain 497 584 2.3E-4 T 11-11-2016 IPR001650 Helicase, C-terminal AUP74_RS03840 ac21610bb3b43069fd05ddf750ad9f37 728 Hamap MF_00983 Probable primosomal protein N' [priA]. 4 727 23.139 T 11-11-2016 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 AUP74_RS03840 ac21610bb3b43069fd05ddf750ad9f37 728 Gene3D G3DSA:3.40.50.300 451 628 3.3E-21 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03840 ac21610bb3b43069fd05ddf750ad9f37 728 Pfam PF00270 DEAD/DEAH box helicase 200 359 9.0E-12 T 11-11-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AUP74_RS03840 ac21610bb3b43069fd05ddf750ad9f37 728 SUPERFAMILY SSF52540 193 367 3.34E-37 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11175 8fb093c94ab12343a32dcdd81ec89391 618 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 367 482 1.5E-8 T 11-11-2016 IPR014031 Beta-ketoacyl synthase, C-terminal AUP74_RS11175 8fb093c94ab12343a32dcdd81ec89391 618 Gene3D G3DSA:3.40.47.10 374 527 2.1E-20 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS11175 8fb093c94ab12343a32dcdd81ec89391 618 SMART SM00825 Beta-ketoacyl synthase 146 535 0.0026 T 11-11-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain AUP74_RS11175 8fb093c94ab12343a32dcdd81ec89391 618 Gene3D G3DSA:3.40.47.10 121 370 4.7E-22 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS11175 8fb093c94ab12343a32dcdd81ec89391 618 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 173 352 1.2E-13 T 11-11-2016 IPR014030 Beta-ketoacyl synthase, N-terminal AUP74_RS11175 8fb093c94ab12343a32dcdd81ec89391 618 SUPERFAMILY SSF53901 151 365 5.04E-28 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS11175 8fb093c94ab12343a32dcdd81ec89391 618 SUPERFAMILY SSF53901 327 528 4.16E-30 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS00725 614c8c24c1936dc05a84d43dec317287 255 Gene3D G3DSA:3.60.15.10 175 231 1.5E-34 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS00725 614c8c24c1936dc05a84d43dec317287 255 Gene3D G3DSA:3.60.15.10 11 143 1.5E-34 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS00725 614c8c24c1936dc05a84d43dec317287 255 SMART SM00849 13 189 6.2E-10 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS00725 614c8c24c1936dc05a84d43dec317287 255 SUPERFAMILY SSF56281 1 229 8.65E-46 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS00725 614c8c24c1936dc05a84d43dec317287 255 Pfam PF12706 Beta-lactamase superfamily domain 26 207 2.0E-23 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS16740 8442623b4efaf97dd4c7a1def0333b42 388 Pfam PF01098 Cell cycle protein 3 355 3.6E-107 T 11-11-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 AUP74_RS16740 8442623b4efaf97dd4c7a1def0333b42 388 Hamap MF_00913 Putative lipid II flippase FtsW [ftsW]. 1 363 36.95 T 11-11-2016 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 AUP74_RS16740 8442623b4efaf97dd4c7a1def0333b42 388 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 3 354 2.1E-126 T 11-11-2016 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 AUP74_RS16740 8442623b4efaf97dd4c7a1def0333b42 388 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 313 337 - T 11-11-2016 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 AUP74_RS00660 5aa252d45beac47b249b5902b19b8cd9 314 Pfam PF13489 Methyltransferase domain 30 149 1.5E-6 T 11-11-2016 AUP74_RS00660 5aa252d45beac47b249b5902b19b8cd9 314 Gene3D G3DSA:3.40.50.150 275 301 2.0E-10 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS00660 5aa252d45beac47b249b5902b19b8cd9 314 Gene3D G3DSA:3.40.50.150 10 160 2.0E-10 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS00660 5aa252d45beac47b249b5902b19b8cd9 314 Gene3D G3DSA:3.40.50.150 198 199 2.0E-10 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS00660 5aa252d45beac47b249b5902b19b8cd9 314 SUPERFAMILY SSF53335 9 174 2.3E-10 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS16125 0dc5e269b5030bc75e7b45fcdaf345f4 484 Gene3D G3DSA:3.40.1060.10 173 286 2.4E-40 T 11-11-2016 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS16125 0dc5e269b5030bc75e7b45fcdaf345f4 484 PRINTS PR00415 Aconitase family signature 88 101 2.3E-47 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS16125 0dc5e269b5030bc75e7b45fcdaf345f4 484 PRINTS PR00415 Aconitase family signature 292 306 2.3E-47 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS16125 0dc5e269b5030bc75e7b45fcdaf345f4 484 PRINTS PR00415 Aconitase family signature 114 122 2.3E-47 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS16125 0dc5e269b5030bc75e7b45fcdaf345f4 484 PRINTS PR00415 Aconitase family signature 125 138 2.3E-47 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS16125 0dc5e269b5030bc75e7b45fcdaf345f4 484 PRINTS PR00415 Aconitase family signature 139 154 2.3E-47 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS16125 0dc5e269b5030bc75e7b45fcdaf345f4 484 PRINTS PR00415 Aconitase family signature 215 228 2.3E-47 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS16125 0dc5e269b5030bc75e7b45fcdaf345f4 484 PRINTS PR00415 Aconitase family signature 406 419 2.3E-47 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS16125 0dc5e269b5030bc75e7b45fcdaf345f4 484 PRINTS PR00415 Aconitase family signature 349 360 2.3E-47 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS16125 0dc5e269b5030bc75e7b45fcdaf345f4 484 PRINTS PR00415 Aconitase family signature 201 214 2.3E-47 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS16125 0dc5e269b5030bc75e7b45fcdaf345f4 484 SUPERFAMILY SSF53732 2 473 6.8E-167 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS16125 0dc5e269b5030bc75e7b45fcdaf345f4 484 ProSitePatterns PS00450 Aconitase family signature 1. 345 361 - T 11-11-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 AUP74_RS16125 0dc5e269b5030bc75e7b45fcdaf345f4 484 Gene3D G3DSA:3.30.499.10 341 473 8.1E-61 T 11-11-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS16125 0dc5e269b5030bc75e7b45fcdaf345f4 484 Gene3D G3DSA:3.30.499.10 302 309 8.1E-61 T 11-11-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS16125 0dc5e269b5030bc75e7b45fcdaf345f4 484 Gene3D G3DSA:3.30.499.10 3 162 1.3E-24 T 11-11-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS16125 0dc5e269b5030bc75e7b45fcdaf345f4 484 Pfam PF00330 Aconitase family (aconitate hydratase) 8 464 1.0E-153 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS16125 0dc5e269b5030bc75e7b45fcdaf345f4 484 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 4 472 2.2E-231 T 11-11-2016 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 AUP74_RS16125 0dc5e269b5030bc75e7b45fcdaf345f4 484 ProSitePatterns PS01244 Aconitase family signature 2. 406 419 - T 11-11-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 AUP74_RS16125 0dc5e269b5030bc75e7b45fcdaf345f4 484 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 2 473 59.916 T 11-11-2016 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 AUP74_RS05130 dec547cc9144c306766e6ada1d6bbb20 304 Gene3D G3DSA:3.30.420.40 146 271 1.7E-27 T 11-11-2016 AUP74_RS05130 dec547cc9144c306766e6ada1d6bbb20 304 Gene3D G3DSA:3.30.420.40 4 145 4.8E-35 T 11-11-2016 AUP74_RS05130 dec547cc9144c306766e6ada1d6bbb20 304 Pfam PF00480 ROK family 6 297 2.0E-33 T 11-11-2016 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AUP74_RS05130 dec547cc9144c306766e6ada1d6bbb20 304 SUPERFAMILY SSF53067 4 300 2.01E-46 T 11-11-2016 AUP74_RS05130 dec547cc9144c306766e6ada1d6bbb20 304 ProSitePatterns PS01125 ROK family signature. 139 166 - T 11-11-2016 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AUP74_RS03020 1bca1e2383d5043cfb3ad66f66b0c748 245 Gene3D G3DSA:3.40.1280.10 74 245 6.5E-64 T 11-11-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AUP74_RS03020 1bca1e2383d5043cfb3ad66f66b0c748 245 SUPERFAMILY SSF75217 73 244 2.31E-55 T 11-11-2016 IPR029028 Alpha/beta knot methyltransferases AUP74_RS03020 1bca1e2383d5043cfb3ad66f66b0c748 245 Gene3D G3DSA:2.40.240.20 1 69 8.0E-23 T 11-11-2016 AUP74_RS03020 1bca1e2383d5043cfb3ad66f66b0c748 245 SUPERFAMILY SSF88697 2 61 3.81E-14 T 11-11-2016 IPR015947 PUA-like domain AUP74_RS03020 1bca1e2383d5043cfb3ad66f66b0c748 245 PIRSF PIRSF015601 2 244 4.5E-62 T 11-11-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AUP74_RS03020 1bca1e2383d5043cfb3ad66f66b0c748 245 Pfam PF04452 RNA methyltransferase 18 240 3.3E-73 T 11-11-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AUP74_RS03020 1bca1e2383d5043cfb3ad66f66b0c748 245 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 3 245 1.1E-66 T 11-11-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 AUP74_RS07435 4727903b4dcd902290529b2cd40d700d 108 Pfam PF11373 Protein of unknown function (DUF3175) 15 99 5.5E-44 T 11-11-2016 IPR021513 Ralstonia phage RSL1, Orf186 AUP74_RS16400 d5955bf7429069ec82801fdc56e93dfe 524 Gene3D G3DSA:3.40.50.980 189 352 2.1E-37 T 11-11-2016 AUP74_RS16400 d5955bf7429069ec82801fdc56e93dfe 524 ProSitePatterns PS00455 Putative AMP-binding domain signature. 183 194 - T 11-11-2016 IPR020845 AMP-binding, conserved site AUP74_RS16400 d5955bf7429069ec82801fdc56e93dfe 524 Pfam PF13193 AMP-binding enzyme C-terminal domain 440 513 2.5E-17 T 11-11-2016 IPR025110 AMP-binding enzyme C-terminal domain AUP74_RS16400 d5955bf7429069ec82801fdc56e93dfe 524 Pfam PF00501 AMP-binding enzyme 22 431 5.8E-103 T 11-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 AUP74_RS16400 d5955bf7429069ec82801fdc56e93dfe 524 Gene3D G3DSA:3.30.300.30 426 521 9.2E-29 T 11-11-2016 AUP74_RS16400 d5955bf7429069ec82801fdc56e93dfe 524 Gene3D G3DSA:2.30.38.10 353 424 3.2E-27 T 11-11-2016 AUP74_RS16400 d5955bf7429069ec82801fdc56e93dfe 524 Gene3D G3DSA:3.40.50.980 12 188 2.7E-34 T 11-11-2016 AUP74_RS16400 d5955bf7429069ec82801fdc56e93dfe 524 SUPERFAMILY SSF56801 9 521 6.02E-146 T 11-11-2016 AUP74_RS13390 75283919a6af66d6830cc2cb2c28f463 207 Pfam PF13649 Methyltransferase domain 62 154 1.5E-8 T 11-11-2016 AUP74_RS13390 75283919a6af66d6830cc2cb2c28f463 207 SUPERFAMILY SSF53335 27 178 2.17E-22 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS13390 75283919a6af66d6830cc2cb2c28f463 207 Gene3D G3DSA:3.40.50.150 20 176 9.7E-26 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS14460 e8e9aec958c6f6812ec6a38d0df5a063 288 Gene3D G3DSA:3.20.20.60 2 285 1.2E-84 T 11-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AUP74_RS14460 e8e9aec958c6f6812ec6a38d0df5a063 288 Pfam PF13714 Phosphoenolpyruvate phosphomutase 5 249 7.6E-46 T 11-11-2016 AUP74_RS14460 e8e9aec958c6f6812ec6a38d0df5a063 288 ProSitePatterns PS00161 Isocitrate lyase signature. 115 120 - T 11-11-2016 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 AUP74_RS14460 e8e9aec958c6f6812ec6a38d0df5a063 288 SUPERFAMILY SSF51621 3 282 3.32E-85 T 11-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AUP74_RS11555 c47e7619269e77e70bf54f69ea1a47c8 88 Pfam PF11280 Protein of unknown function (DUF3081) 7 83 2.5E-24 T 11-11-2016 IPR021432 Protein of unknown function DUF3081 AUP74_RS08240 5cdcb5f1a525c2b42359726d214c0769 332 SUPERFAMILY SSF143865 14 265 5.36E-64 T 11-11-2016 AUP74_RS08240 5cdcb5f1a525c2b42359726d214c0769 332 Pfam PF01544 CorA-like Mg2+ transporter protein 42 327 2.8E-67 T 11-11-2016 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 AUP74_RS08240 5cdcb5f1a525c2b42359726d214c0769 332 Gene3D G3DSA:3.30.460.20 29 140 1.1E-6 T 11-11-2016 AUP74_RS08240 5cdcb5f1a525c2b42359726d214c0769 332 Gene3D G3DSA:1.20.58.340 145 252 2.4E-22 T 11-11-2016 AUP74_RS08240 5cdcb5f1a525c2b42359726d214c0769 332 SUPERFAMILY SSF144083 267 330 2.62E-15 T 11-11-2016 AUP74_RS08240 5cdcb5f1a525c2b42359726d214c0769 332 Gene3D G3DSA:1.20.58.340 258 332 8.7E-22 T 11-11-2016 AUP74_RS09410 090a88f09cf4759e855d90c6b138ca79 371 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 1 357 57.096 T 11-11-2016 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AUP74_RS09410 090a88f09cf4759e855d90c6b138ca79 371 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 3 367 7.0E-170 T 11-11-2016 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AUP74_RS09410 090a88f09cf4759e855d90c6b138ca79 371 Pfam PF01702 Queuine tRNA-ribosyltransferase 126 359 3.9E-92 T 11-11-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AUP74_RS09410 090a88f09cf4759e855d90c6b138ca79 371 SUPERFAMILY SSF51713 1 362 1.26E-162 T 11-11-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AUP74_RS09410 090a88f09cf4759e855d90c6b138ca79 371 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 3 367 2.3E-162 T 11-11-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AUP74_RS09410 090a88f09cf4759e855d90c6b138ca79 371 Gene3D G3DSA:3.20.20.105 1 365 5.7E-170 T 11-11-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AUP74_RS02730 cc1b4cf0efe316b48c4392ba4fdfacd1 491 Gene3D G3DSA:1.25.40.10 15 125 5.4E-12 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS02730 cc1b4cf0efe316b48c4392ba4fdfacd1 491 Pfam PF13469 Sulfotransferase family 252 436 5.2E-31 T 11-11-2016 AUP74_RS02730 cc1b4cf0efe316b48c4392ba4fdfacd1 491 SUPERFAMILY SSF52540 247 472 2.32E-42 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS02730 cc1b4cf0efe316b48c4392ba4fdfacd1 491 Pfam PF14559 Tetratricopeptide repeat 97 152 4.2E-6 T 11-11-2016 AUP74_RS02730 cc1b4cf0efe316b48c4392ba4fdfacd1 491 SUPERFAMILY SSF48452 12 208 1.1E-13 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS02730 cc1b4cf0efe316b48c4392ba4fdfacd1 491 Gene3D G3DSA:1.25.40.10 126 207 7.9E-6 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS02730 cc1b4cf0efe316b48c4392ba4fdfacd1 491 Gene3D G3DSA:3.40.50.300 246 472 2.9E-19 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04570 10bf45ddfa61950fc2c10b60ccbfdb5e 168 PIRSF PIRSF004749 1 168 1.6E-61 T 11-11-2016 IPR023635 Peptide deformylase AUP74_RS04570 10bf45ddfa61950fc2c10b60ccbfdb5e 168 SUPERFAMILY SSF56420 3 165 1.05E-65 T 11-11-2016 IPR023635 Peptide deformylase AUP74_RS04570 10bf45ddfa61950fc2c10b60ccbfdb5e 168 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 161 1.2E-59 T 11-11-2016 IPR023635 Peptide deformylase AUP74_RS04570 10bf45ddfa61950fc2c10b60ccbfdb5e 168 Hamap MF_00163 Peptide deformylase [def]. 2 163 33.392 T 11-11-2016 IPR023635 Peptide deformylase AUP74_RS04570 10bf45ddfa61950fc2c10b60ccbfdb5e 168 Pfam PF01327 Polypeptide deformylase 5 153 4.6E-55 T 11-11-2016 IPR023635 Peptide deformylase AUP74_RS04570 10bf45ddfa61950fc2c10b60ccbfdb5e 168 PRINTS PR01576 Peptide deformylase signature 121 150 9.2E-41 T 11-11-2016 IPR023635 Peptide deformylase AUP74_RS04570 10bf45ddfa61950fc2c10b60ccbfdb5e 168 PRINTS PR01576 Peptide deformylase signature 90 101 9.2E-41 T 11-11-2016 IPR023635 Peptide deformylase AUP74_RS04570 10bf45ddfa61950fc2c10b60ccbfdb5e 168 PRINTS PR01576 Peptide deformylase signature 102 120 9.2E-41 T 11-11-2016 IPR023635 Peptide deformylase AUP74_RS04570 10bf45ddfa61950fc2c10b60ccbfdb5e 168 PRINTS PR01576 Peptide deformylase signature 33 62 9.2E-41 T 11-11-2016 IPR023635 Peptide deformylase AUP74_RS04570 10bf45ddfa61950fc2c10b60ccbfdb5e 168 Gene3D G3DSA:3.90.45.10 5 165 2.1E-69 T 11-11-2016 IPR023635 Peptide deformylase AUP74_RS08630 492867acd0dce2ddd198603b30844d1f 192 Gene3D G3DSA:1.10.3210.10 4 184 5.1E-36 T 11-11-2016 IPR006674 HD domain AUP74_RS08630 492867acd0dce2ddd198603b30844d1f 192 Pfam PF13023 HD domain 14 175 2.2E-42 T 11-11-2016 IPR006674 HD domain AUP74_RS08630 492867acd0dce2ddd198603b30844d1f 192 SUPERFAMILY SSF109604 5 181 8.52E-41 T 11-11-2016 AUP74_RS11180 59e0b6290660230459b4da6f02b8b222 176 SMART SM00530 2 57 1.7E-13 T 11-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AUP74_RS11180 59e0b6290660230459b4da6f02b8b222 176 Gene3D G3DSA:2.60.120.10 85 172 3.4E-14 T 11-11-2016 IPR014710 RmlC-like jelly roll fold AUP74_RS11180 59e0b6290660230459b4da6f02b8b222 176 Gene3D G3DSA:1.10.260.40 2 60 3.9E-18 T 11-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AUP74_RS11180 59e0b6290660230459b4da6f02b8b222 176 SUPERFAMILY SSF47413 2 62 9.92E-15 T 11-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AUP74_RS11180 59e0b6290660230459b4da6f02b8b222 176 Pfam PF07883 Cupin domain 101 169 2.2E-13 T 11-11-2016 IPR013096 Cupin 2, conserved barrel AUP74_RS11180 59e0b6290660230459b4da6f02b8b222 176 SUPERFAMILY SSF51182 42 174 1.69E-22 T 11-11-2016 IPR011051 RmlC-like cupin domain AUP74_RS11180 59e0b6290660230459b4da6f02b8b222 176 Pfam PF01381 Helix-turn-helix 3 57 5.9E-12 T 11-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AUP74_RS00965 30a2aef488c4692190bd47aa47aad0bf 146 SUPERFAMILY SSF55961 1 144 2.96E-34 T 11-11-2016 AUP74_RS00965 30a2aef488c4692190bd47aa47aad0bf 146 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 12 134 6.5E-32 T 11-11-2016 IPR005031 Coenzyme Q-binding protein COQ10, START domain AUP74_RS00965 30a2aef488c4692190bd47aa47aad0bf 146 Gene3D G3DSA:3.30.530.20 1 144 6.2E-45 T 11-11-2016 IPR023393 START-like domain AUP74_RS10235 260a39dfff64e2950787e2e686a4e948 344 Gene3D G3DSA:3.30.250.10 271 326 5.7E-26 T 11-11-2016 IPR023400 DNA recombination and repair protein RecA, C-terminal AUP74_RS10235 260a39dfff64e2950787e2e686a4e948 344 PRINTS PR00142 RecA protein signature 127 156 9.6E-84 T 11-11-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AUP74_RS10235 260a39dfff64e2950787e2e686a4e948 344 PRINTS PR00142 RecA protein signature 165 194 9.6E-84 T 11-11-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AUP74_RS10235 260a39dfff64e2950787e2e686a4e948 344 PRINTS PR00142 RecA protein signature 93 122 9.6E-84 T 11-11-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AUP74_RS10235 260a39dfff64e2950787e2e686a4e948 344 PRINTS PR00142 RecA protein signature 210 238 9.6E-84 T 11-11-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AUP74_RS10235 260a39dfff64e2950787e2e686a4e948 344 PRINTS PR00142 RecA protein signature 243 272 9.6E-84 T 11-11-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AUP74_RS10235 260a39dfff64e2950787e2e686a4e948 344 PRINTS PR00142 RecA protein signature 297 314 9.6E-84 T 11-11-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AUP74_RS10235 260a39dfff64e2950787e2e686a4e948 344 SMART SM00382 57 228 5.9E-12 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS10235 260a39dfff64e2950787e2e686a4e948 344 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 4 323 7.3E-172 T 11-11-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AUP74_RS10235 260a39dfff64e2950787e2e686a4e948 344 SUPERFAMILY SSF52540 4 267 2.16E-68 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS10235 260a39dfff64e2950787e2e686a4e948 344 SUPERFAMILY SSF54752 270 324 5.62E-20 T 11-11-2016 IPR023400 DNA recombination and repair protein RecA, C-terminal AUP74_RS10235 260a39dfff64e2950787e2e686a4e948 344 Gene3D G3DSA:3.40.50.300 27 267 4.3E-87 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS10235 260a39dfff64e2950787e2e686a4e948 344 ProSitePatterns PS00321 recA signature. 213 221 - T 11-11-2016 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 AUP74_RS10235 260a39dfff64e2950787e2e686a4e948 344 Hamap MF_00268 Protein RecA [recA]. 5 329 51.243 T 11-11-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AUP74_RS10235 260a39dfff64e2950787e2e686a4e948 344 Pfam PF00154 recA bacterial DNA recombination protein 7 268 1.6E-145 T 11-11-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AUP74_RS03330 3f3ac70f13945bb1b7f69ec4a260d60c 1115 Gene3D G3DSA:3.40.50.300 156 214 1.1E-4 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03330 3f3ac70f13945bb1b7f69ec4a260d60c 1115 SUPERFAMILY SSF52540 483 537 1.36E-7 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03330 3f3ac70f13945bb1b7f69ec4a260d60c 1115 SUPERFAMILY SSF52540 157 300 1.36E-7 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03330 3f3ac70f13945bb1b7f69ec4a260d60c 1115 SUPERFAMILY SSF52540 567 631 1.36E-7 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03330 3f3ac70f13945bb1b7f69ec4a260d60c 1115 Pfam PF04851 Type III restriction enzyme, res subunit 132 276 3.0E-7 T 11-11-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 AUP74_RS14135 c1a55f6d14d083dddc3ba5e221c13f42 160 Gene3D G3DSA:1.10.10.10 9 59 7.7E-22 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS14135 c1a55f6d14d083dddc3ba5e221c13f42 160 Gene3D G3DSA:3.30.70.920 60 157 4.9E-27 T 11-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AUP74_RS14135 c1a55f6d14d083dddc3ba5e221c13f42 160 Pfam PF13412 Winged helix-turn-helix DNA-binding 8 54 1.5E-18 T 11-11-2016 AUP74_RS14135 c1a55f6d14d083dddc3ba5e221c13f42 160 SUPERFAMILY SSF46785 8 68 5.94E-17 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS14135 c1a55f6d14d083dddc3ba5e221c13f42 160 SMART SM00344 8 117 1.7E-42 T 11-11-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AUP74_RS14135 c1a55f6d14d083dddc3ba5e221c13f42 160 Pfam PF01037 Lrp/AsnC ligand binding domain 74 147 1.1E-21 T 11-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AUP74_RS14135 c1a55f6d14d083dddc3ba5e221c13f42 160 SUPERFAMILY SSF54909 71 156 1.88E-20 T 11-11-2016 IPR011008 Dimeric alpha-beta barrel AUP74_RS14135 c1a55f6d14d083dddc3ba5e221c13f42 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 8 24 6.5E-14 T 11-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 AUP74_RS14135 c1a55f6d14d083dddc3ba5e221c13f42 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 24 35 6.5E-14 T 11-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 AUP74_RS14135 c1a55f6d14d083dddc3ba5e221c13f42 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 35 54 6.5E-14 T 11-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 AUP74_RS05795 c2b3990f2bee6916f02e19db51a58bf1 167 Pfam PF00929 Exonuclease 1 156 2.9E-29 T 11-11-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III AUP74_RS05795 c2b3990f2bee6916f02e19db51a58bf1 167 SUPERFAMILY SSF53098 1 166 9.11E-41 T 11-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 AUP74_RS05795 c2b3990f2bee6916f02e19db51a58bf1 167 Hamap MF_00045 Oligoribonuclease [orn]. 1 167 38.251 T 11-11-2016 IPR022894 Oligoribonuclease GO:0016788 AUP74_RS05795 c2b3990f2bee6916f02e19db51a58bf1 167 SMART SM00479 1 166 2.2E-13 T 11-11-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III AUP74_RS05795 c2b3990f2bee6916f02e19db51a58bf1 167 Gene3D G3DSA:3.30.420.10 1 166 3.9E-66 T 11-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 AUP74_RS10890 fdb571c0496a4abfaedf909b7d9be1fd 74 TIGRFAM TIGR03141 cytochro_ccmD: heme exporter protein CcmD 12 57 1.0E-17 T 11-11-2016 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 AUP74_RS10890 fdb571c0496a4abfaedf909b7d9be1fd 74 Pfam PF04995 Heme exporter protein D (CcmD) 16 57 1.5E-17 T 11-11-2016 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 AUP74_RS06620 b88ef61cb4d9c4664cf56edb50804244 348 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 2 348 2.5E-127 T 11-11-2016 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AUP74_RS06620 b88ef61cb4d9c4664cf56edb50804244 348 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 342 42.237 T 11-11-2016 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AUP74_RS06620 b88ef61cb4d9c4664cf56edb50804244 348 Gene3D G3DSA:3.30.360.10 158 316 3.0E-56 T 11-11-2016 AUP74_RS06620 b88ef61cb4d9c4664cf56edb50804244 348 SUPERFAMILY SSF51735 2 172 2.26E-54 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS06620 b88ef61cb4d9c4664cf56edb50804244 348 SUPERFAMILY SSF55347 149 316 7.38E-50 T 11-11-2016 AUP74_RS06620 b88ef61cb4d9c4664cf56edb50804244 348 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 160 319 7.9E-16 T 11-11-2016 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AUP74_RS06620 b88ef61cb4d9c4664cf56edb50804244 348 SMART SM00859 3 141 2.4E-56 T 11-11-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 AUP74_RS06620 b88ef61cb4d9c4664cf56edb50804244 348 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 140 8.6E-37 T 11-11-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 AUP74_RS06620 b88ef61cb4d9c4664cf56edb50804244 348 Gene3D G3DSA:3.40.50.720 2 157 4.1E-62 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS13800 dcb8f69b0a4fb8f8ffd55659503aadb9 346 Pfam PF13524 Glycosyl transferases group 1 228 320 2.3E-12 T 11-11-2016 AUP74_RS05825 318cb91f8a0c9f2af2691425c665a0de 307 Pfam PF01715 IPP transferase 31 279 7.8E-87 T 11-11-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 AUP74_RS05825 318cb91f8a0c9f2af2691425c665a0de 307 SUPERFAMILY SSF52540 155 258 7.87E-7 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05825 318cb91f8a0c9f2af2691425c665a0de 307 SUPERFAMILY SSF52540 1 79 7.87E-7 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05825 318cb91f8a0c9f2af2691425c665a0de 307 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 1 304 29.077 T 11-11-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 AUP74_RS05825 318cb91f8a0c9f2af2691425c665a0de 307 SUPERFAMILY SSF52540 1 142 1.2E-18 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05825 318cb91f8a0c9f2af2691425c665a0de 307 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 1 279 2.5E-101 T 11-11-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 AUP74_RS05825 318cb91f8a0c9f2af2691425c665a0de 307 Gene3D G3DSA:3.40.50.300 1 164 1.0E-52 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05825 318cb91f8a0c9f2af2691425c665a0de 307 Gene3D G3DSA:1.10.287.890 195 277 6.9E-35 T 11-11-2016 AUP74_RS06455 ec7fc7528c6bfc17f544ae82edf4fe45 192 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 2.4E-5 T 11-11-2016 AUP74_RS06455 ec7fc7528c6bfc17f544ae82edf4fe45 192 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 2.4E-5 T 11-11-2016 AUP74_RS06455 ec7fc7528c6bfc17f544ae82edf4fe45 192 PRINTS PR00097 Anthranilate synthase component II signature 99 107 1.2E-36 T 11-11-2016 AUP74_RS06455 ec7fc7528c6bfc17f544ae82edf4fe45 192 PRINTS PR00097 Anthranilate synthase component II signature 74 85 1.2E-36 T 11-11-2016 AUP74_RS06455 ec7fc7528c6bfc17f544ae82edf4fe45 192 PRINTS PR00097 Anthranilate synthase component II signature 169 182 1.2E-36 T 11-11-2016 AUP74_RS06455 ec7fc7528c6bfc17f544ae82edf4fe45 192 PRINTS PR00097 Anthranilate synthase component II signature 119 131 1.2E-36 T 11-11-2016 AUP74_RS06455 ec7fc7528c6bfc17f544ae82edf4fe45 192 PRINTS PR00097 Anthranilate synthase component II signature 47 56 1.2E-36 T 11-11-2016 AUP74_RS06455 ec7fc7528c6bfc17f544ae82edf4fe45 192 PRINTS PR00097 Anthranilate synthase component II signature 2 16 1.2E-36 T 11-11-2016 AUP74_RS06455 ec7fc7528c6bfc17f544ae82edf4fe45 192 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 191 4.2E-86 T 11-11-2016 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AUP74_RS06455 ec7fc7528c6bfc17f544ae82edf4fe45 192 Gene3D G3DSA:3.40.50.880 1 191 4.3E-67 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS06455 ec7fc7528c6bfc17f544ae82edf4fe45 192 PRINTS PR00096 Glutamine amidotransferase superfamily signature 169 182 7.1E-14 T 11-11-2016 AUP74_RS06455 ec7fc7528c6bfc17f544ae82edf4fe45 192 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 7.1E-14 T 11-11-2016 AUP74_RS06455 ec7fc7528c6bfc17f544ae82edf4fe45 192 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 7.1E-14 T 11-11-2016 AUP74_RS06455 ec7fc7528c6bfc17f544ae82edf4fe45 192 SUPERFAMILY SSF52317 1 191 1.76E-54 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS06455 ec7fc7528c6bfc17f544ae82edf4fe45 192 Pfam PF00117 Glutamine amidotransferase class-I 4 190 2.0E-54 T 11-11-2016 IPR017926 Glutamine amidotransferase AUP74_RS08090 052b79a84b5fc7cad5ac2c47a2a9dd46 143 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 3.0E-39 T 11-11-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 AUP74_RS08090 052b79a84b5fc7cad5ac2c47a2a9dd46 143 PRINTS PR01651 Protein-export SecG membrane protein signature 38 54 3.0E-39 T 11-11-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 AUP74_RS08090 052b79a84b5fc7cad5ac2c47a2a9dd46 143 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 3.0E-39 T 11-11-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 AUP74_RS08090 052b79a84b5fc7cad5ac2c47a2a9dd46 143 PRINTS PR01651 Protein-export SecG membrane protein signature 54 76 3.0E-39 T 11-11-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 AUP74_RS08090 052b79a84b5fc7cad5ac2c47a2a9dd46 143 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 4 73 1.1E-24 T 11-11-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 AUP74_RS08090 052b79a84b5fc7cad5ac2c47a2a9dd46 143 Pfam PF03840 Preprotein translocase SecG subunit 5 72 1.1E-19 T 11-11-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 AUP74_RS08940 dd8cb9ca71b929c33e7c2b54a6793b08 681 SUPERFAMILY SSF51338 236 301 2.11E-13 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS08940 dd8cb9ca71b929c33e7c2b54a6793b08 681 SUPERFAMILY SSF51338 613 637 2.11E-13 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS08940 dd8cb9ca71b929c33e7c2b54a6793b08 681 Gene3D G3DSA:2.30.40.10 596 624 6.0E-5 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS08940 dd8cb9ca71b929c33e7c2b54a6793b08 681 Pfam PF01979 Amidohydrolase family 320 639 8.5E-11 T 11-11-2016 IPR006680 Amidohydrolase-related GO:0016787 AUP74_RS08940 dd8cb9ca71b929c33e7c2b54a6793b08 681 SUPERFAMILY SSF51556 300 446 5.22E-40 T 11-11-2016 IPR032466 Metal-dependent hydrolase AUP74_RS08940 dd8cb9ca71b929c33e7c2b54a6793b08 681 SUPERFAMILY SSF51556 480 614 5.22E-40 T 11-11-2016 IPR032466 Metal-dependent hydrolase AUP74_RS08940 dd8cb9ca71b929c33e7c2b54a6793b08 681 Gene3D G3DSA:3.20.20.140 306 446 2.9E-43 T 11-11-2016 AUP74_RS08940 dd8cb9ca71b929c33e7c2b54a6793b08 681 Gene3D G3DSA:3.20.20.140 479 595 2.9E-43 T 11-11-2016 AUP74_RS08940 dd8cb9ca71b929c33e7c2b54a6793b08 681 Gene3D G3DSA:2.30.40.10 625 653 4.7E-21 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS08940 dd8cb9ca71b929c33e7c2b54a6793b08 681 Gene3D G3DSA:2.30.40.10 243 302 4.7E-21 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS05810 dd598e0dbce77a1fabb3c97a4b36044b 161 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 11 139 7.1E-36 T 11-11-2016 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 AUP74_RS05810 dd598e0dbce77a1fabb3c97a4b36044b 161 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 27 145 1.4E-41 T 11-11-2016 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 AUP74_RS05810 dd598e0dbce77a1fabb3c97a4b36044b 161 Gene3D G3DSA:3.40.50.300 5 156 5.6E-46 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05810 dd598e0dbce77a1fabb3c97a4b36044b 161 SUPERFAMILY SSF52540 31 138 1.77E-23 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04085 0d232281ca75f3152df5931930976479 218 Gene3D G3DSA:3.30.63.10 58 97 6.8E-26 T 11-11-2016 AUP74_RS04085 0d232281ca75f3152df5931930976479 218 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 17 194 5.1E-72 T 11-11-2016 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 AUP74_RS04085 0d232281ca75f3152df5931930976479 218 Gene3D G3DSA:3.40.50.300 13 31 2.3E-49 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04085 0d232281ca75f3152df5931930976479 218 Gene3D G3DSA:3.40.50.300 98 214 2.3E-49 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04085 0d232281ca75f3152df5931930976479 218 SMART SM00072 15 197 6.2E-62 T 11-11-2016 IPR008145 Guanylate kinase/L-type calcium channel beta subunit AUP74_RS04085 0d232281ca75f3152df5931930976479 218 Hamap MF_00328 Guanylate kinase [gmk]. 14 197 35.632 T 11-11-2016 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 AUP74_RS04085 0d232281ca75f3152df5931930976479 218 Pfam PF00625 Guanylate kinase 17 194 1.8E-50 T 11-11-2016 IPR008145 Guanylate kinase/L-type calcium channel beta subunit AUP74_RS04085 0d232281ca75f3152df5931930976479 218 ProSitePatterns PS00856 Guanylate kinase-like signature. 50 67 - T 11-11-2016 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 AUP74_RS04085 0d232281ca75f3152df5931930976479 218 SUPERFAMILY SSF52540 15 199 5.34E-69 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04085 0d232281ca75f3152df5931930976479 218 Gene3D G3DSA:3.40.50.300 32 57 3.7E-4 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS08945 8984cf793929d83cf55fa5f0b230d7cc 436 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 328 340 - T 11-11-2016 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site AUP74_RS08945 8984cf793929d83cf55fa5f0b230d7cc 436 Hamap MF_01279 Xaa-Pro dipeptidase [pepQ]. 1 436 52.312 T 11-11-2016 IPR022846 Xaa-Pro dipeptidase GO:0016795 AUP74_RS08945 8984cf793929d83cf55fa5f0b230d7cc 436 SUPERFAMILY SSF55920 156 431 6.15E-52 T 11-11-2016 IPR000994 Peptidase M24, structural domain AUP74_RS08945 8984cf793929d83cf55fa5f0b230d7cc 436 Gene3D G3DSA:3.90.230.10 154 433 1.1E-52 T 11-11-2016 IPR000994 Peptidase M24, structural domain AUP74_RS08945 8984cf793929d83cf55fa5f0b230d7cc 436 Pfam PF00557 Metallopeptidase family M24 162 423 9.3E-44 T 11-11-2016 IPR000994 Peptidase M24, structural domain AUP74_RS13535 db3ae6ce5cf34897e2d2a668a83a838d 284 Gene3D G3DSA:3.20.20.70 1 283 1.5E-86 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS13535 db3ae6ce5cf34897e2d2a668a83a838d 284 Pfam PF05853 beta-keto acid cleavage enzyme 5 283 2.9E-77 T 11-11-2016 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00600+2.3.1.24 AUP74_RS13535 db3ae6ce5cf34897e2d2a668a83a838d 284 SUPERFAMILY SSF51395 24 113 1.17E-5 T 11-11-2016 AUP74_RS01350 08a63f076c4c1309b7cf830c0207ff55 138 Gene3D G3DSA:3.10.580.10 1 118 3.5E-30 T 11-11-2016 AUP74_RS01350 08a63f076c4c1309b7cf830c0207ff55 138 Pfam PF00571 CBS domain 68 118 7.1E-9 T 11-11-2016 IPR000644 CBS domain AUP74_RS01350 08a63f076c4c1309b7cf830c0207ff55 138 Pfam PF00571 CBS domain 3 53 2.2E-11 T 11-11-2016 IPR000644 CBS domain AUP74_RS01350 08a63f076c4c1309b7cf830c0207ff55 138 SMART SM00116 75 123 3.3 T 11-11-2016 IPR000644 CBS domain AUP74_RS01350 08a63f076c4c1309b7cf830c0207ff55 138 SMART SM00116 10 57 9.6E-9 T 11-11-2016 IPR000644 CBS domain AUP74_RS01350 08a63f076c4c1309b7cf830c0207ff55 138 SUPERFAMILY SSF54631 1 129 4.67E-30 T 11-11-2016 AUP74_RS15335 b6eaa3a04cb28c9c3d79e8dad8c28629 747 SUPERFAMILY SSF81301 222 397 8.34E-64 T 11-11-2016 AUP74_RS15335 b6eaa3a04cb28c9c3d79e8dad8c28629 747 SUPERFAMILY SSF81271 417 478 6.98E-20 T 11-11-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 AUP74_RS15335 b6eaa3a04cb28c9c3d79e8dad8c28629 747 Pfam PF02824 TGS domain 419 478 3.6E-23 T 11-11-2016 IPR004095 TGS KEGG: 00970+6.1.1.3 AUP74_RS15335 b6eaa3a04cb28c9c3d79e8dad8c28629 747 Gene3D G3DSA:3.10.20.30 418 480 3.7E-25 T 11-11-2016 IPR012675 Beta-grasp domain AUP74_RS15335 b6eaa3a04cb28c9c3d79e8dad8c28629 747 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 71 742 4.1E-186 T 11-11-2016 IPR004811 RelA/SpoT family GO:0015969 AUP74_RS15335 b6eaa3a04cb28c9c3d79e8dad8c28629 747 Pfam PF13291 ACT domain 666 743 3.8E-18 T 11-11-2016 IPR002912 ACT domain GO:0008152|GO:0016597 AUP74_RS15335 b6eaa3a04cb28c9c3d79e8dad8c28629 747 Gene3D G3DSA:3.30.460.10 208 355 3.2E-53 T 11-11-2016 AUP74_RS15335 b6eaa3a04cb28c9c3d79e8dad8c28629 747 Pfam PF13328 HD domain 55 205 3.1E-40 T 11-11-2016 IPR003607 HD/PDEase domain AUP74_RS15335 b6eaa3a04cb28c9c3d79e8dad8c28629 747 SUPERFAMILY SSF55021 667 744 6.34E-14 T 11-11-2016 AUP74_RS15335 b6eaa3a04cb28c9c3d79e8dad8c28629 747 SUPERFAMILY SSF109604 57 221 3.45E-44 T 11-11-2016 AUP74_RS15335 b6eaa3a04cb28c9c3d79e8dad8c28629 747 SMART SM00954 265 375 6.0E-65 T 11-11-2016 IPR007685 RelA/SpoT GO:0015969 AUP74_RS15335 b6eaa3a04cb28c9c3d79e8dad8c28629 747 Gene3D G3DSA:3.30.70.260 668 741 1.5E-17 T 11-11-2016 AUP74_RS15335 b6eaa3a04cb28c9c3d79e8dad8c28629 747 Pfam PF04607 Region found in RelA / SpoT proteins 265 374 1.5E-37 T 11-11-2016 IPR007685 RelA/SpoT GO:0015969 AUP74_RS10345 52635fa1bb9d4e176b7ea393ec6d00bb 636 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 19 74 3.1E-10 T 11-11-2016 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 AUP74_RS10345 52635fa1bb9d4e176b7ea393ec6d00bb 636 Gene3D G3DSA:3.40.50.980 74 259 9.3E-31 T 11-11-2016 AUP74_RS10345 52635fa1bb9d4e176b7ea393ec6d00bb 636 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 1 634 4.6E-288 T 11-11-2016 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16|Reactome: R-HSA-77111 AUP74_RS10345 52635fa1bb9d4e176b7ea393ec6d00bb 636 SUPERFAMILY SSF56801 2 626 1.44E-126 T 11-11-2016 AUP74_RS10345 52635fa1bb9d4e176b7ea393ec6d00bb 636 Pfam PF13193 AMP-binding enzyme C-terminal domain 529 598 8.4E-6 T 11-11-2016 IPR025110 AMP-binding enzyme C-terminal domain AUP74_RS10345 52635fa1bb9d4e176b7ea393ec6d00bb 636 Gene3D G3DSA:3.30.300.30 510 617 9.0E-18 T 11-11-2016 AUP74_RS10345 52635fa1bb9d4e176b7ea393ec6d00bb 636 Gene3D G3DSA:3.40.50.980 260 390 3.9E-13 T 11-11-2016 AUP74_RS10345 52635fa1bb9d4e176b7ea393ec6d00bb 636 Pfam PF00501 AMP-binding enzyme 77 510 8.7E-48 T 11-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 AUP74_RS10345 52635fa1bb9d4e176b7ea393ec6d00bb 636 ProSitePatterns PS00455 Putative AMP-binding domain signature. 254 265 - T 11-11-2016 IPR020845 AMP-binding, conserved site AUP74_RS01065 2108db9c16b0d63776c5faaba7bce8de 348 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 108 327 5.6E-9 T 11-11-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AUP74_RS03695 635330c1ca923b8b7568b9b132a1df3a 361 PIRSF PIRSF029285 1 331 2.6E-106 T 11-11-2016 IPR014553 Predicted aminopeptidase AUP74_RS03695 635330c1ca923b8b7568b9b132a1df3a 361 Pfam PF10023 Putative aminopeptidase 9 324 2.5E-112 T 11-11-2016 IPR014553 Predicted aminopeptidase AUP74_RS05790 9f0bd6dd1495acf3a17f70650dbec471 343 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 45 343 34.841 T 11-11-2016 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 AUP74_RS05790 9f0bd6dd1495acf3a17f70650dbec471 343 Pfam PF03193 Protein of unknown function, DUF258 106 280 1.5E-54 T 11-11-2016 IPR010914 RsgA type GTPase domain GO:0003924|GO:0005525 AUP74_RS05790 9f0bd6dd1495acf3a17f70650dbec471 343 Gene3D G3DSA:1.10.40.50 280 342 1.6E-21 T 11-11-2016 AUP74_RS05790 9f0bd6dd1495acf3a17f70650dbec471 343 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 80 337 9.1E-77 T 11-11-2016 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 AUP74_RS05790 9f0bd6dd1495acf3a17f70650dbec471 343 SUPERFAMILY SSF52540 120 339 1.82E-54 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05790 9f0bd6dd1495acf3a17f70650dbec471 343 Gene3D G3DSA:3.40.50.300 120 279 4.2E-51 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS08475 62f4aa1aab4df14846c724cd5fc32e4e 991 Gene3D G3DSA:2.170.130.10 58 164 2.9E-20 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS08475 62f4aa1aab4df14846c724cd5fc32e4e 991 Gene3D G3DSA:2.40.170.20 660 784 2.6E-50 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS08475 62f4aa1aab4df14846c724cd5fc32e4e 991 Gene3D G3DSA:2.40.170.20 165 244 2.6E-50 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS08475 62f4aa1aab4df14846c724cd5fc32e4e 991 Gene3D G3DSA:2.40.170.20 454 493 2.6E-50 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS08475 62f4aa1aab4df14846c724cd5fc32e4e 991 Gene3D G3DSA:2.40.170.20 284 417 2.6E-50 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS08475 62f4aa1aab4df14846c724cd5fc32e4e 991 Gene3D G3DSA:2.40.170.20 580 625 2.6E-50 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS08475 62f4aa1aab4df14846c724cd5fc32e4e 991 Gene3D G3DSA:2.40.170.20 821 991 2.6E-50 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS08475 62f4aa1aab4df14846c724cd5fc32e4e 991 Pfam PF00593 TonB dependent receptor 667 989 1.0E-27 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS08475 62f4aa1aab4df14846c724cd5fc32e4e 991 SUPERFAMILY SSF56935 563 760 9.16E-84 T 11-11-2016 AUP74_RS08475 62f4aa1aab4df14846c724cd5fc32e4e 991 SUPERFAMILY SSF56935 827 991 9.16E-84 T 11-11-2016 AUP74_RS08475 62f4aa1aab4df14846c724cd5fc32e4e 991 SUPERFAMILY SSF56935 31 229 9.16E-84 T 11-11-2016 AUP74_RS08475 62f4aa1aab4df14846c724cd5fc32e4e 991 SUPERFAMILY SSF56935 285 494 9.16E-84 T 11-11-2016 AUP74_RS08475 62f4aa1aab4df14846c724cd5fc32e4e 991 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 38 991 1.1E-188 T 11-11-2016 IPR010104 Bacterial TonB-dependent receptor AUP74_RS08475 62f4aa1aab4df14846c724cd5fc32e4e 991 Pfam PF07715 TonB-dependent Receptor Plug Domain 57 159 1.1E-17 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS02995 f7f80704eeda44828e39456eb55f42d3 458 Gene3D G3DSA:3.40.50.1480 7 195 1.8E-132 T 11-11-2016 AUP74_RS02995 f7f80704eeda44828e39456eb55f42d3 458 Gene3D G3DSA:3.40.50.1480 371 458 1.8E-132 T 11-11-2016 AUP74_RS02995 f7f80704eeda44828e39456eb55f42d3 458 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 194 370 7.7E-58 T 11-11-2016 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AUP74_RS02995 f7f80704eeda44828e39456eb55f42d3 458 SMART SM00997 194 370 1.2E-85 T 11-11-2016 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AUP74_RS02995 f7f80704eeda44828e39456eb55f42d3 458 SUPERFAMILY SSF51735 194 371 2.63E-52 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS02995 f7f80704eeda44828e39456eb55f42d3 458 PIRSF PIRSF001109 1 458 2.0E-182 T 11-11-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AUP74_RS02995 f7f80704eeda44828e39456eb55f42d3 458 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 8 450 1.2E-157 T 11-11-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AUP74_RS02995 f7f80704eeda44828e39456eb55f42d3 458 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 216 233 - T 11-11-2016 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AUP74_RS02995 f7f80704eeda44828e39456eb55f42d3 458 Gene3D G3DSA:3.40.50.720 196 369 6.4E-44 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS02995 f7f80704eeda44828e39456eb55f42d3 458 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 3 450 44.51 T 11-11-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AUP74_RS02995 f7f80704eeda44828e39456eb55f42d3 458 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 7 144 1.6E-73 T 11-11-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AUP74_RS02995 f7f80704eeda44828e39456eb55f42d3 458 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 79 93 - T 11-11-2016 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AUP74_RS02995 f7f80704eeda44828e39456eb55f42d3 458 SMART SM00996 7 457 8.8E-279 T 11-11-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AUP74_RS02995 f7f80704eeda44828e39456eb55f42d3 458 SUPERFAMILY SSF52283 371 458 5.38E-110 T 11-11-2016 AUP74_RS02995 f7f80704eeda44828e39456eb55f42d3 458 SUPERFAMILY SSF52283 5 193 5.38E-110 T 11-11-2016 AUP74_RS14710 6824d6a5cf56cc00fc7f3251e26aa09b 790 SUPERFAMILY SSF46955 404 476 6.77E-17 T 11-11-2016 IPR009061 Putative DNA-binding domain AUP74_RS14710 6824d6a5cf56cc00fc7f3251e26aa09b 790 Pfam PF03147 Ferredoxin-fold anticodon binding domain 697 790 2.7E-29 T 11-11-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 AUP74_RS14710 6824d6a5cf56cc00fc7f3251e26aa09b 790 SMART SM00896 697 790 2.3E-43 T 11-11-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 AUP74_RS14710 6824d6a5cf56cc00fc7f3251e26aa09b 790 Gene3D G3DSA:3.30.56.20 403 476 1.7E-22 T 11-11-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 AUP74_RS14710 6824d6a5cf56cc00fc7f3251e26aa09b 790 SUPERFAMILY SSF54991 692 790 9.15E-30 T 11-11-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 AUP74_RS14710 6824d6a5cf56cc00fc7f3251e26aa09b 790 SUPERFAMILY SSF56037 196 392 1.8E-76 T 11-11-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 AUP74_RS14710 6824d6a5cf56cc00fc7f3251e26aa09b 790 Gene3D G3DSA:3.50.40.10 198 391 7.3E-85 T 11-11-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 AUP74_RS14710 6824d6a5cf56cc00fc7f3251e26aa09b 790 SUPERFAMILY SSF50249 35 197 1.27E-47 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS14710 6824d6a5cf56cc00fc7f3251e26aa09b 790 Pfam PF03483 B3/4 domain 212 384 2.6E-73 T 11-11-2016 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 AUP74_RS14710 6824d6a5cf56cc00fc7f3251e26aa09b 790 Gene3D G3DSA:3.30.70.380 699 790 1.7E-30 T 11-11-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 AUP74_RS14710 6824d6a5cf56cc00fc7f3251e26aa09b 790 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 790 2.2E-259 T 11-11-2016 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 AUP74_RS14710 6824d6a5cf56cc00fc7f3251e26aa09b 790 Pfam PF01588 Putative tRNA binding domain 45 145 7.0E-20 T 11-11-2016 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 AUP74_RS14710 6824d6a5cf56cc00fc7f3251e26aa09b 790 SUPERFAMILY SSF55681 468 685 1.64E-50 T 11-11-2016 AUP74_RS14710 6824d6a5cf56cc00fc7f3251e26aa09b 790 Gene3D G3DSA:2.40.50.140 40 153 1.7E-43 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS14710 6824d6a5cf56cc00fc7f3251e26aa09b 790 Pfam PF03484 tRNA synthetase B5 domain 406 472 6.9E-16 T 11-11-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 AUP74_RS14710 6824d6a5cf56cc00fc7f3251e26aa09b 790 Gene3D G3DSA:3.30.56.10 155 183 1.8E-26 T 11-11-2016 AUP74_RS14710 6824d6a5cf56cc00fc7f3251e26aa09b 790 Gene3D G3DSA:3.30.56.10 1 38 1.8E-26 T 11-11-2016 AUP74_RS14710 6824d6a5cf56cc00fc7f3251e26aa09b 790 SMART SM00874 403 472 6.4E-24 T 11-11-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 AUP74_RS14710 6824d6a5cf56cc00fc7f3251e26aa09b 790 SMART SM00873 212 385 4.7E-101 T 11-11-2016 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 AUP74_RS14710 6824d6a5cf56cc00fc7f3251e26aa09b 790 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 784 45.213 T 11-11-2016 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 AUP74_RS14710 6824d6a5cf56cc00fc7f3251e26aa09b 790 Gene3D G3DSA:3.30.930.10 496 686 2.2E-65 T 11-11-2016 AUP74_RS00040 51cb48d09ed9161f4763adcdfc7ad1a5 89 SUPERFAMILY SSF55594 4 87 4.45E-26 T 11-11-2016 IPR000032 Phosphocarrier protein HPr-like AUP74_RS00040 51cb48d09ed9161f4763adcdfc7ad1a5 89 PRINTS PR00107 Phosphocarrier protein signature 13 29 2.1E-13 T 11-11-2016 IPR000032 Phosphocarrier protein HPr-like AUP74_RS00040 51cb48d09ed9161f4763adcdfc7ad1a5 89 PRINTS PR00107 Phosphocarrier protein signature 38 53 2.1E-13 T 11-11-2016 IPR000032 Phosphocarrier protein HPr-like AUP74_RS00040 51cb48d09ed9161f4763adcdfc7ad1a5 89 PRINTS PR00107 Phosphocarrier protein signature 53 70 2.1E-13 T 11-11-2016 IPR000032 Phosphocarrier protein HPr-like AUP74_RS00040 51cb48d09ed9161f4763adcdfc7ad1a5 89 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 3.9E-27 T 11-11-2016 IPR000032 Phosphocarrier protein HPr-like AUP74_RS00040 51cb48d09ed9161f4763adcdfc7ad1a5 89 Pfam PF00381 PTS HPr component phosphorylation site 5 82 5.0E-25 T 11-11-2016 IPR000032 Phosphocarrier protein HPr-like AUP74_RS00040 51cb48d09ed9161f4763adcdfc7ad1a5 89 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 11-11-2016 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site AUP74_RS00040 51cb48d09ed9161f4763adcdfc7ad1a5 89 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 11-11-2016 IPR002114 Phosphotransferase system, HPr serine phosphorylation site AUP74_RS00040 51cb48d09ed9161f4763adcdfc7ad1a5 89 Gene3D G3DSA:3.30.1340.10 1 87 1.3E-30 T 11-11-2016 IPR000032 Phosphocarrier protein HPr-like AUP74_RS01715 a13e71278ca1d58138968257917d5787 254 Pfam PF03929 PepSY-associated TM region 7 229 9.9E-10 T 11-11-2016 IPR005625 PepSY-associated TM protein AUP74_RS12375 2fbe2b761b0c1996e95b9760c4dd1719 67 Pfam PF10981 Protein of unknown function (DUF2788) 14 64 2.9E-23 T 11-11-2016 IPR021249 Protein of unknown function DUF2788 AUP74_RS01695 d446b16259c9a19ab97be93f4fa2b32c 285 Pfam PF01497 Periplasmic binding protein 35 257 1.4E-13 T 11-11-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 AUP74_RS01695 d446b16259c9a19ab97be93f4fa2b32c 285 Gene3D G3DSA:3.40.50.1980 153 275 8.0E-10 T 11-11-2016 AUP74_RS01695 d446b16259c9a19ab97be93f4fa2b32c 285 Gene3D G3DSA:3.40.50.1980 71 143 7.1E-9 T 11-11-2016 AUP74_RS01695 d446b16259c9a19ab97be93f4fa2b32c 285 SUPERFAMILY SSF53807 32 275 5.1E-25 T 11-11-2016 AUP74_RS02435 0d43eb43c93fbd1d2a9800a080fad863 411 SUPERFAMILY SSF51905 287 403 2.81E-56 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS02435 0d43eb43c93fbd1d2a9800a080fad863 411 SUPERFAMILY SSF51905 6 193 2.81E-56 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS02435 0d43eb43c93fbd1d2a9800a080fad863 411 Gene3D G3DSA:3.50.50.60 4 196 5.8E-46 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS02435 0d43eb43c93fbd1d2a9800a080fad863 411 Gene3D G3DSA:3.50.50.60 298 337 5.8E-46 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS02435 0d43eb43c93fbd1d2a9800a080fad863 411 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 314 327 - T 11-11-2016 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 AUP74_RS02435 0d43eb43c93fbd1d2a9800a080fad863 411 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 7 409 4.0E-119 T 11-11-2016 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 AUP74_RS02435 0d43eb43c93fbd1d2a9800a080fad863 411 Pfam PF01494 FAD binding domain 6 360 8.4E-27 T 11-11-2016 IPR002938 FAD-binding domain GO:0071949 AUP74_RS02435 0d43eb43c93fbd1d2a9800a080fad863 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 315 331 2.2E-18 T 11-11-2016 AUP74_RS02435 0d43eb43c93fbd1d2a9800a080fad863 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 300 315 2.2E-18 T 11-11-2016 AUP74_RS02435 0d43eb43c93fbd1d2a9800a080fad863 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 2.2E-18 T 11-11-2016 AUP74_RS02435 0d43eb43c93fbd1d2a9800a080fad863 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 172 187 2.2E-18 T 11-11-2016 AUP74_RS01570 14a229cd5ef2aeb81f7f7e65d4b9bf85 365 SUPERFAMILY SSF53850 24 360 5.22E-78 T 11-11-2016 AUP74_RS01570 14a229cd5ef2aeb81f7f7e65d4b9bf85 365 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 175 194 3.8E-45 T 11-11-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AUP74_RS01570 14a229cd5ef2aeb81f7f7e65d4b9bf85 365 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 88 101 3.8E-45 T 11-11-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AUP74_RS01570 14a229cd5ef2aeb81f7f7e65d4b9bf85 365 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 45 66 3.8E-45 T 11-11-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AUP74_RS01570 14a229cd5ef2aeb81f7f7e65d4b9bf85 365 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 121 137 3.8E-45 T 11-11-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AUP74_RS01570 14a229cd5ef2aeb81f7f7e65d4b9bf85 365 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 262 281 3.8E-45 T 11-11-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AUP74_RS01570 14a229cd5ef2aeb81f7f7e65d4b9bf85 365 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 307 333 3.8E-45 T 11-11-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AUP74_RS01570 14a229cd5ef2aeb81f7f7e65d4b9bf85 365 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 29 45 3.8E-45 T 11-11-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AUP74_RS01570 14a229cd5ef2aeb81f7f7e65d4b9bf85 365 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 72 86 3.8E-45 T 11-11-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AUP74_RS01570 14a229cd5ef2aeb81f7f7e65d4b9bf85 365 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 212 231 3.8E-45 T 11-11-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AUP74_RS01570 14a229cd5ef2aeb81f7f7e65d4b9bf85 365 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 152 166 3.8E-45 T 11-11-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AUP74_RS01570 14a229cd5ef2aeb81f7f7e65d4b9bf85 365 Gene3D G3DSA:3.40.190.10 145 311 2.1E-54 T 11-11-2016 AUP74_RS01570 14a229cd5ef2aeb81f7f7e65d4b9bf85 365 Pfam PF13416 Bacterial extracellular solute-binding protein 41 316 2.1E-23 T 11-11-2016 AUP74_RS01570 14a229cd5ef2aeb81f7f7e65d4b9bf85 365 Gene3D G3DSA:3.40.190.10 25 144 1.5E-21 T 11-11-2016 AUP74_RS01570 14a229cd5ef2aeb81f7f7e65d4b9bf85 365 PIRSF PIRSF019574 3 363 1.4E-97 T 11-11-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AUP74_RS08905 e769417e130a2475de0e5f9962562aed 244 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 46 219 2.8E-50 T 11-11-2016 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 AUP74_RS08905 e769417e130a2475de0e5f9962562aed 244 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 50 215 6.9E-61 T 11-11-2016 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 AUP74_RS11570 bbb816209b3f0cf1b0a28bed4d89f8a0 385 SUPERFAMILY SSF51735 6 141 1.73E-13 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS11570 bbb816209b3f0cf1b0a28bed4d89f8a0 385 Gene3D G3DSA:3.40.50.720 7 160 4.3E-18 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS11570 bbb816209b3f0cf1b0a28bed4d89f8a0 385 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 9 108 2.7E-12 T 11-11-2016 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 AUP74_RS02295 6cc4e71e8886c356d18a3dd718fa1f95 438 Hamap MF_01105 Amino-acid acetyltransferase [argA]. 1 434 177.82 T 11-11-2016 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 AUP74_RS02295 6cc4e71e8886c356d18a3dd718fa1f95 438 Gene3D G3DSA:3.40.630.30 285 430 7.5E-37 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS02295 6cc4e71e8886c356d18a3dd718fa1f95 438 Pfam PF00696 Amino acid kinase family 26 232 3.6E-19 T 11-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase AUP74_RS02295 6cc4e71e8886c356d18a3dd718fa1f95 438 PIRSF PIRSF000423 1 434 3.8E-164 T 11-11-2016 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 AUP74_RS02295 6cc4e71e8886c356d18a3dd718fa1f95 438 Gene3D G3DSA:3.40.1160.10 23 279 8.1E-57 T 11-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase AUP74_RS02295 6cc4e71e8886c356d18a3dd718fa1f95 438 Pfam PF00583 Acetyltransferase (GNAT) family 329 396 1.4E-8 T 11-11-2016 IPR000182 GNAT domain GO:0008080 AUP74_RS02295 6cc4e71e8886c356d18a3dd718fa1f95 438 SUPERFAMILY SSF55729 239 412 2.36E-19 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS02295 6cc4e71e8886c356d18a3dd718fa1f95 438 SUPERFAMILY SSF53633 7 283 1.24E-57 T 11-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase AUP74_RS02295 6cc4e71e8886c356d18a3dd718fa1f95 438 TIGRFAM TIGR01890 N-Ac-Glu-synth: amino-acid N-acetyltransferase 9 433 1.6E-160 T 11-11-2016 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 AUP74_RS07945 0445b263cdf1ad99e3a35719d928685c 646 SUPERFAMILY SSF53067 4 183 4.32E-65 T 11-11-2016 AUP74_RS07945 0445b263cdf1ad99e3a35719d928685c 646 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 192 205 - T 11-11-2016 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 AUP74_RS07945 0445b263cdf1ad99e3a35719d928685c 646 Gene3D G3DSA:3.30.420.40 193 229 2.2E-32 T 11-11-2016 AUP74_RS07945 0445b263cdf1ad99e3a35719d928685c 646 Gene3D G3DSA:3.30.420.40 319 361 2.2E-32 T 11-11-2016 AUP74_RS07945 0445b263cdf1ad99e3a35719d928685c 646 Pfam PF00012 Hsp70 protein 4 603 1.3E-260 T 11-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AUP74_RS07945 0445b263cdf1ad99e3a35719d928685c 646 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 11-11-2016 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 AUP74_RS07945 0445b263cdf1ad99e3a35719d928685c 646 Gene3D G3DSA:3.30.420.40 119 192 3.7E-64 T 11-11-2016 AUP74_RS07945 0445b263cdf1ad99e3a35719d928685c 646 Gene3D G3DSA:3.30.420.40 4 52 3.7E-64 T 11-11-2016 AUP74_RS07945 0445b263cdf1ad99e3a35719d928685c 646 SUPERFAMILY SSF100920 384 540 6.41E-62 T 11-11-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 AUP74_RS07945 0445b263cdf1ad99e3a35719d928685c 646 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 337 351 - T 11-11-2016 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 AUP74_RS07945 0445b263cdf1ad99e3a35719d928685c 646 Gene3D G3DSA:3.90.640.10 230 315 3.9E-30 T 11-11-2016 AUP74_RS07945 0445b263cdf1ad99e3a35719d928685c 646 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 638 36.735 T 11-11-2016 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 AUP74_RS07945 0445b263cdf1ad99e3a35719d928685c 646 SUPERFAMILY SSF100934 507 610 5.49E-16 T 11-11-2016 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 AUP74_RS07945 0445b263cdf1ad99e3a35719d928685c 646 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 603 8.3E-288 T 11-11-2016 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 AUP74_RS07945 0445b263cdf1ad99e3a35719d928685c 646 Gene3D G3DSA:3.30.30.30 53 109 3.0E-30 T 11-11-2016 AUP74_RS07945 0445b263cdf1ad99e3a35719d928685c 646 SUPERFAMILY SSF53067 187 382 2.14E-67 T 11-11-2016 AUP74_RS07945 0445b263cdf1ad99e3a35719d928685c 646 Gene3D G3DSA:2.60.34.10 390 531 9.5E-70 T 11-11-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 AUP74_RS07945 0445b263cdf1ad99e3a35719d928685c 646 Gene3D G3DSA:1.20.1270.10 532 603 2.5E-25 T 11-11-2016 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 AUP74_RS07945 0445b263cdf1ad99e3a35719d928685c 646 PRINTS PR00301 70kDa heat shock protein signature 334 350 3.9E-81 T 11-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AUP74_RS07945 0445b263cdf1ad99e3a35719d928685c 646 PRINTS PR00301 70kDa heat shock protein signature 3 16 3.9E-81 T 11-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AUP74_RS07945 0445b263cdf1ad99e3a35719d928685c 646 PRINTS PR00301 70kDa heat shock protein signature 469 485 3.9E-81 T 11-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AUP74_RS07945 0445b263cdf1ad99e3a35719d928685c 646 PRINTS PR00301 70kDa heat shock protein signature 365 385 3.9E-81 T 11-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AUP74_RS07945 0445b263cdf1ad99e3a35719d928685c 646 PRINTS PR00301 70kDa heat shock protein signature 31 43 3.9E-81 T 11-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AUP74_RS07945 0445b263cdf1ad99e3a35719d928685c 646 PRINTS PR00301 70kDa heat shock protein signature 54 62 3.9E-81 T 11-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AUP74_RS07945 0445b263cdf1ad99e3a35719d928685c 646 PRINTS PR00301 70kDa heat shock protein signature 138 158 3.9E-81 T 11-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AUP74_RS07945 0445b263cdf1ad99e3a35719d928685c 646 PRINTS PR00301 70kDa heat shock protein signature 198 208 3.9E-81 T 11-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AUP74_RS07945 0445b263cdf1ad99e3a35719d928685c 646 PRINTS PR00301 70kDa heat shock protein signature 388 407 3.9E-81 T 11-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AUP74_RS00100 af752d634782bb56dac79c1bdfc613ec 481 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 9 474 91.568 T 11-11-2016 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AUP74_RS00100 af752d634782bb56dac79c1bdfc613ec 481 Pfam PF01425 Amidase 22 463 7.0E-161 T 11-11-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AUP74_RS00100 af752d634782bb56dac79c1bdfc613ec 481 ProSitePatterns PS00571 Amidases signature. 149 180 - T 11-11-2016 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 AUP74_RS00100 af752d634782bb56dac79c1bdfc613ec 481 SUPERFAMILY SSF75304 2 477 1.57E-164 T 11-11-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AUP74_RS00100 af752d634782bb56dac79c1bdfc613ec 481 Gene3D G3DSA:3.90.1300.10 2 478 3.7E-181 T 11-11-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AUP74_RS00100 af752d634782bb56dac79c1bdfc613ec 481 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 13 473 1.1E-181 T 11-11-2016 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AUP74_RS01305 f963bbe851a1defb9316b73788b43b3f 219 SUPERFAMILY SSF52833 4 216 1.39E-50 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS01305 f963bbe851a1defb9316b73788b43b3f 219 Gene3D G3DSA:3.40.30.10 6 212 4.9E-53 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS01305 f963bbe851a1defb9316b73788b43b3f 219 Pfam PF01323 DSBA-like thioredoxin domain 8 210 1.7E-41 T 11-11-2016 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 AUP74_RS00560 61280113ebf86dc0949dec7e6a1f70d3 255 Pfam PF09836 Putative DNA-binding domain 14 99 7.0E-26 T 11-11-2016 IPR018640 Putative DNA-binding domain, bacteria AUP74_RS04975 35e837d84a3da35af4982065c0e8203d 105 Pfam PF13591 MerR HTH family regulatory protein 20 103 2.7E-24 T 11-11-2016 AUP74_RS04975 35e837d84a3da35af4982065c0e8203d 105 SUPERFAMILY SSF46955 21 102 1.28E-5 T 11-11-2016 IPR009061 Putative DNA-binding domain AUP74_RS04975 35e837d84a3da35af4982065c0e8203d 105 Gene3D G3DSA:1.10.1660.10 21 103 8.1E-7 T 11-11-2016 AUP74_RS02335 e9683f30be720cf5bd64d0ab911e7015 260 Pfam PF11932 Protein of unknown function (DUF3450) 15 253 2.9E-77 T 11-11-2016 IPR016866 Uncharacterised conserved protein UCP028069 AUP74_RS02335 e9683f30be720cf5bd64d0ab911e7015 260 PIRSF PIRSF028069 5 260 2.3E-65 T 11-11-2016 IPR016866 Uncharacterised conserved protein UCP028069 AUP74_RS03010 19bdf602796a2f7e9e50b266b716c002 215 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 91 181 9.7E-7 T 11-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 AUP74_RS03010 19bdf602796a2f7e9e50b266b716c002 215 Gene3D G3DSA:1.10.150.240 20 85 1.0E-15 T 11-11-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 AUP74_RS03010 19bdf602796a2f7e9e50b266b716c002 215 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 186 9.3E-28 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS03010 19bdf602796a2f7e9e50b266b716c002 215 Gene3D G3DSA:3.40.50.1000 5 19 4.4E-41 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS03010 19bdf602796a2f7e9e50b266b716c002 215 Gene3D G3DSA:3.40.50.1000 87 210 4.4E-41 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS03010 19bdf602796a2f7e9e50b266b716c002 215 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 62 186 1.2E-18 T 11-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 AUP74_RS03010 19bdf602796a2f7e9e50b266b716c002 215 SUPERFAMILY SSF56784 5 212 1.21E-51 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS09545 86a34d3ffbb502dff6601891b2ec0123 164 SUPERFAMILY SSF49777 7 162 2.75E-51 T 11-11-2016 IPR008914 Phosphatidylethanolamine-binding protein AUP74_RS09545 86a34d3ffbb502dff6601891b2ec0123 164 Pfam PF01161 Phosphatidylethanolamine-binding protein 24 161 8.1E-40 T 11-11-2016 IPR008914 Phosphatidylethanolamine-binding protein AUP74_RS09545 86a34d3ffbb502dff6601891b2ec0123 164 Gene3D G3DSA:3.90.280.10 6 162 1.3E-56 T 11-11-2016 IPR008914 Phosphatidylethanolamine-binding protein AUP74_RS09545 86a34d3ffbb502dff6601891b2ec0123 164 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 27 161 2.6E-44 T 11-11-2016 IPR005247 YbhB/YbcL AUP74_RS07835 ee4c03115e3161e71d8d690c7e2290db 316 SUPERFAMILY SSF46955 25 128 7.78E-21 T 11-11-2016 IPR009061 Putative DNA-binding domain AUP74_RS07835 ee4c03115e3161e71d8d690c7e2290db 316 Pfam PF13411 MerR HTH family regulatory protein 26 92 1.0E-18 T 11-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AUP74_RS07835 ee4c03115e3161e71d8d690c7e2290db 316 ProSitePatterns PS00552 MerR-type HTH domain signature. 28 51 - T 11-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AUP74_RS07835 ee4c03115e3161e71d8d690c7e2290db 316 SMART SM00422 25 94 5.3E-23 T 11-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AUP74_RS07835 ee4c03115e3161e71d8d690c7e2290db 316 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 61 81 4.0E-5 T 11-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AUP74_RS07835 ee4c03115e3161e71d8d690c7e2290db 316 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 26 37 4.0E-5 T 11-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AUP74_RS07835 ee4c03115e3161e71d8d690c7e2290db 316 Gene3D G3DSA:1.10.1660.10 25 133 1.5E-22 T 11-11-2016 AUP74_RS03155 a9c92fac4864741ce445fd8b2f9b51a0 733 Pfam PF07715 TonB-dependent Receptor Plug Domain 47 156 1.3E-17 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS03155 a9c92fac4864741ce445fd8b2f9b51a0 733 SUPERFAMILY SSF56935 464 733 5.49E-124 T 11-11-2016 AUP74_RS03155 a9c92fac4864741ce445fd8b2f9b51a0 733 SUPERFAMILY SSF56935 30 435 5.49E-124 T 11-11-2016 AUP74_RS03155 a9c92fac4864741ce445fd8b2f9b51a0 733 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 716 733 - T 11-11-2016 IPR010917 TonB-dependent receptor, conserved site AUP74_RS03155 a9c92fac4864741ce445fd8b2f9b51a0 733 Pfam PF00593 TonB dependent receptor 474 731 2.3E-27 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS03155 a9c92fac4864741ce445fd8b2f9b51a0 733 Gene3D G3DSA:2.40.170.20 463 733 1.9E-88 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS03155 a9c92fac4864741ce445fd8b2f9b51a0 733 Gene3D G3DSA:2.40.170.20 168 430 1.9E-88 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS03155 a9c92fac4864741ce445fd8b2f9b51a0 733 Gene3D G3DSA:2.170.130.10 31 164 3.8E-33 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS08760 4ba04041e457e5f954e7290af67f515d 380 Pfam PF00534 Glycosyl transferases group 1 189 353 3.7E-22 T 11-11-2016 IPR001296 Glycosyl transferase, family 1 AUP74_RS08760 4ba04041e457e5f954e7290af67f515d 380 Pfam PF13439 Glycosyltransferase Family 4 16 175 4.9E-9 T 11-11-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AUP74_RS08760 4ba04041e457e5f954e7290af67f515d 380 SUPERFAMILY SSF53756 9 380 6.73E-57 T 11-11-2016 AUP74_RS08760 4ba04041e457e5f954e7290af67f515d 380 Gene3D G3DSA:3.40.50.2000 183 356 1.5E-20 T 11-11-2016 AUP74_RS14430 d301e275672df70062b66edb8e19b64f 260 SMART SM00866 109 250 2.4E-19 T 11-11-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 AUP74_RS14430 d301e275672df70062b66edb8e19b64f 260 Pfam PF07702 UTRA domain 112 250 4.5E-21 T 11-11-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 AUP74_RS14430 d301e275672df70062b66edb8e19b64f 260 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 61 1.3E-6 T 11-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AUP74_RS14430 d301e275672df70062b66edb8e19b64f 260 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 61 77 1.3E-6 T 11-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AUP74_RS14430 d301e275672df70062b66edb8e19b64f 260 Gene3D G3DSA:1.10.10.10 18 90 1.2E-23 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS14430 d301e275672df70062b66edb8e19b64f 260 SMART SM00345 28 87 4.6E-19 T 11-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AUP74_RS14430 d301e275672df70062b66edb8e19b64f 260 SUPERFAMILY SSF64288 76 256 1.73E-32 T 11-11-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain AUP74_RS14430 d301e275672df70062b66edb8e19b64f 260 Pfam PF00392 Bacterial regulatory proteins, gntR family 24 87 6.2E-20 T 11-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AUP74_RS14430 d301e275672df70062b66edb8e19b64f 260 SUPERFAMILY SSF46785 20 89 2.24E-20 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS14430 d301e275672df70062b66edb8e19b64f 260 Gene3D G3DSA:3.40.1410.10 100 255 1.1E-29 T 11-11-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain AUP74_RS09675 c58afc9068cda27a144374177e894150 481 Pfam PF00199 Catalase 10 387 3.9E-185 T 11-11-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 AUP74_RS09675 c58afc9068cda27a144374177e894150 481 Pfam PF06628 Catalase-related immune-responsive 415 478 3.6E-19 T 11-11-2016 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 AUP74_RS09675 c58afc9068cda27a144374177e894150 481 PIRSF PIRSF038928 1 481 1.4E-232 T 11-11-2016 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 AUP74_RS09675 c58afc9068cda27a144374177e894150 481 PRINTS PR00067 Catalase signature 23 46 2.9E-66 T 11-11-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 AUP74_RS09675 c58afc9068cda27a144374177e894150 481 PRINTS PR00067 Catalase signature 322 348 2.9E-66 T 11-11-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 AUP74_RS09675 c58afc9068cda27a144374177e894150 481 PRINTS PR00067 Catalase signature 85 103 2.9E-66 T 11-11-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 AUP74_RS09675 c58afc9068cda27a144374177e894150 481 PRINTS PR00067 Catalase signature 125 143 2.9E-66 T 11-11-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 AUP74_RS09675 c58afc9068cda27a144374177e894150 481 PRINTS PR00067 Catalase signature 106 123 2.9E-66 T 11-11-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 AUP74_RS09675 c58afc9068cda27a144374177e894150 481 PRINTS PR00067 Catalase signature 290 317 2.9E-66 T 11-11-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 AUP74_RS09675 c58afc9068cda27a144374177e894150 481 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 335 343 - T 11-11-2016 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 AUP74_RS09675 c58afc9068cda27a144374177e894150 481 SUPERFAMILY SSF56634 3 479 1.31E-202 T 11-11-2016 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 AUP74_RS09675 c58afc9068cda27a144374177e894150 481 ProSitePatterns PS00438 Catalase proximal active site signature. 46 62 - T 11-11-2016 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 AUP74_RS09675 c58afc9068cda27a144374177e894150 481 Gene3D G3DSA:2.40.180.10 3 359 6.2E-175 T 11-11-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 AUP74_RS09675 c58afc9068cda27a144374177e894150 481 SMART SM01060 10 391 1.8E-276 T 11-11-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 AUP74_RS05680 7428667752fbeeba8ce17e0154284eaf 302 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 210 287 2.7E-14 T 11-11-2016 IPR006260 TonB, C-terminal GO:0006810 AUP74_RS05680 7428667752fbeeba8ce17e0154284eaf 302 SUPERFAMILY SSF74653 182 290 2.88E-17 T 11-11-2016 AUP74_RS05680 7428667752fbeeba8ce17e0154284eaf 302 Gene3D G3DSA:3.30.1150.10 186 289 9.0E-20 T 11-11-2016 AUP74_RS05680 7428667752fbeeba8ce17e0154284eaf 302 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 210 288 1.7E-12 T 11-11-2016 IPR006260 TonB, C-terminal GO:0006810 AUP74_RS14055 964ccd1e170437f24c6e0774f43c6ea7 490 SUPERFAMILY SSF75304 4 461 3.4E-115 T 11-11-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AUP74_RS14055 964ccd1e170437f24c6e0774f43c6ea7 490 Pfam PF01425 Amidase 26 452 1.1E-85 T 11-11-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AUP74_RS14055 964ccd1e170437f24c6e0774f43c6ea7 490 ProSitePatterns PS00571 Amidases signature. 153 184 - T 11-11-2016 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 AUP74_RS14055 964ccd1e170437f24c6e0774f43c6ea7 490 Gene3D G3DSA:3.90.1300.10 2 463 1.2E-110 T 11-11-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AUP74_RS01460 bc21abd1420ad64ba0f193b447942fba 362 SUPERFAMILY SSF53383 7 353 6.32E-77 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase AUP74_RS01460 bc21abd1420ad64ba0f193b447942fba 362 Gene3D G3DSA:3.90.1150.10 255 353 1.1E-27 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS01460 bc21abd1420ad64ba0f193b447942fba 362 Pfam PF00155 Aminotransferase class I and II 26 349 1.1E-54 T 11-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AUP74_RS01460 bc21abd1420ad64ba0f193b447942fba 362 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 9 352 5.5E-92 T 11-11-2016 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 AUP74_RS01460 bc21abd1420ad64ba0f193b447942fba 362 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 5 353 55.127 T 11-11-2016 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 AUP74_RS01460 bc21abd1420ad64ba0f193b447942fba 362 Gene3D G3DSA:3.40.640.10 41 254 3.5E-63 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AUP74_RS06435 f4b8cddc7a626ca7b371469a341d6e2f 234 Pfam PF00483 Nucleotidyl transferase 12 154 2.4E-21 T 11-11-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 AUP74_RS06435 f4b8cddc7a626ca7b371469a341d6e2f 234 SUPERFAMILY SSF53448 11 229 3.15E-52 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases AUP74_RS06435 f4b8cddc7a626ca7b371469a341d6e2f 234 Gene3D G3DSA:3.90.550.10 11 229 1.5E-51 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases AUP74_RS13070 0690c329c3bd90287e2afd024a853588 314 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 9 308 1.1E-39 T 11-11-2016 IPR020801 Polyketide synthase, acyl transferase domain AUP74_RS13070 0690c329c3bd90287e2afd024a853588 314 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 5 293 9.4E-114 T 11-11-2016 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 AUP74_RS13070 0690c329c3bd90287e2afd024a853588 314 Gene3D G3DSA:3.40.366.10 199 310 1.7E-70 T 11-11-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 AUP74_RS13070 0690c329c3bd90287e2afd024a853588 314 Gene3D G3DSA:3.40.366.10 3 124 1.7E-70 T 11-11-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 AUP74_RS13070 0690c329c3bd90287e2afd024a853588 314 SUPERFAMILY SSF52151 5 130 8.72E-75 T 11-11-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 AUP74_RS13070 0690c329c3bd90287e2afd024a853588 314 SUPERFAMILY SSF52151 200 300 8.72E-75 T 11-11-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 AUP74_RS13070 0690c329c3bd90287e2afd024a853588 314 PIRSF PIRSF000446 3 313 1.2E-118 T 11-11-2016 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 AUP74_RS13070 0690c329c3bd90287e2afd024a853588 314 SUPERFAMILY SSF55048 130 199 1.19E-18 T 11-11-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 AUP74_RS13070 0690c329c3bd90287e2afd024a853588 314 Gene3D G3DSA:3.30.70.250 127 198 8.4E-31 T 11-11-2016 AUP74_RS13070 0690c329c3bd90287e2afd024a853588 314 Pfam PF00698 Acyl transferase domain 8 283 2.9E-37 T 11-11-2016 IPR014043 Acyl transferase AUP74_RS00020 9eb37289e1bebc771f62a1a4e22f7245 484 PRINTS PR00045 Sigma-54 factor signature 399 410 4.5E-32 T 11-11-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 AUP74_RS00020 9eb37289e1bebc771f62a1a4e22f7245 484 PRINTS PR00045 Sigma-54 factor signature 383 395 4.5E-32 T 11-11-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 AUP74_RS00020 9eb37289e1bebc771f62a1a4e22f7245 484 PRINTS PR00045 Sigma-54 factor signature 457 475 4.5E-32 T 11-11-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 AUP74_RS00020 9eb37289e1bebc771f62a1a4e22f7245 484 PRINTS PR00045 Sigma-54 factor signature 193 210 4.5E-32 T 11-11-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 AUP74_RS00020 9eb37289e1bebc771f62a1a4e22f7245 484 Pfam PF04552 Sigma-54, DNA binding domain 324 482 2.1E-71 T 11-11-2016 IPR007634 RNA polymerase sigma factor 54, DNA-binding AUP74_RS00020 9eb37289e1bebc771f62a1a4e22f7245 484 Pfam PF04963 Sigma-54 factor, core binding domain 122 310 2.0E-56 T 11-11-2016 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 AUP74_RS00020 9eb37289e1bebc771f62a1a4e22f7245 484 PIRSF PIRSF000774 1 484 1.2E-154 T 11-11-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 AUP74_RS00020 9eb37289e1bebc771f62a1a4e22f7245 484 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 4 49 7.0E-16 T 11-11-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 AUP74_RS00020 9eb37289e1bebc771f62a1a4e22f7245 484 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 10 481 2.1E-153 T 11-11-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 AUP74_RS00020 9eb37289e1bebc771f62a1a4e22f7245 484 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 371 390 - T 11-11-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 AUP74_RS00020 9eb37289e1bebc771f62a1a4e22f7245 484 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 462 469 - T 11-11-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 AUP74_RS09450 54700b067bed5a73199b0a8b87b9986e 406 SUPERFAMILY SSF69864 178 400 1.15E-96 T 11-11-2016 AUP74_RS09450 54700b067bed5a73199b0a8b87b9986e 406 TIGRFAM TIGR00032 argG: argininosuccinate synthase 6 398 1.9E-143 T 11-11-2016 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AUP74_RS09450 54700b067bed5a73199b0a8b87b9986e 406 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 10 18 - T 11-11-2016 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AUP74_RS09450 54700b067bed5a73199b0a8b87b9986e 406 Hamap MF_00005 Argininosuccinate synthase [argG]. 4 403 54.103 T 11-11-2016 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AUP74_RS09450 54700b067bed5a73199b0a8b87b9986e 406 Pfam PF00764 Arginosuccinate synthase 8 398 2.9E-157 T 11-11-2016 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AUP74_RS09450 54700b067bed5a73199b0a8b87b9986e 406 Gene3D G3DSA:3.90.1260.10 161 360 2.4E-99 T 11-11-2016 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AUP74_RS09450 54700b067bed5a73199b0a8b87b9986e 406 Gene3D G3DSA:1.20.5.470 374 396 1.2E-6 T 11-11-2016 AUP74_RS09450 54700b067bed5a73199b0a8b87b9986e 406 Gene3D G3DSA:3.40.50.620 5 160 2.6E-67 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS09450 54700b067bed5a73199b0a8b87b9986e 406 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 118 129 - T 11-11-2016 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AUP74_RS09450 54700b067bed5a73199b0a8b87b9986e 406 SUPERFAMILY SSF52402 5 209 2.65E-50 T 11-11-2016 AUP74_RS12270 3da765fdc356c13e755d66ccbd90adbf 299 SUPERFAMILY SSF50891 162 262 1.75E-34 T 11-11-2016 IPR029000 Cyclophilin-like domain AUP74_RS12270 3da765fdc356c13e755d66ccbd90adbf 299 SUPERFAMILY SSF50891 54 124 1.75E-34 T 11-11-2016 IPR029000 Cyclophilin-like domain AUP74_RS12270 3da765fdc356c13e755d66ccbd90adbf 299 Gene3D G3DSA:2.40.100.10 39 126 2.9E-29 T 11-11-2016 IPR029000 Cyclophilin-like domain AUP74_RS12270 3da765fdc356c13e755d66ccbd90adbf 299 Gene3D G3DSA:2.40.100.10 165 221 2.9E-29 T 11-11-2016 IPR029000 Cyclophilin-like domain AUP74_RS12270 3da765fdc356c13e755d66ccbd90adbf 299 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 59 238 5.1E-37 T 11-11-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 AUP74_RS05830 ace84500e57543141d703b2beaec72f2 94 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 1 64 27.46 T 11-11-2016 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 AUP74_RS05830 ace84500e57543141d703b2beaec72f2 94 Gene3D G3DSA:2.30.30.100 1 69 7.9E-36 T 11-11-2016 AUP74_RS05830 ace84500e57543141d703b2beaec72f2 94 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 6 64 1.1E-29 T 11-11-2016 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 AUP74_RS05830 ace84500e57543141d703b2beaec72f2 94 SUPERFAMILY SSF50182 7 68 3.66E-24 T 11-11-2016 IPR010920 LSM domain AUP74_RS14845 7816cc6736a0a60c63373dee0f687c61 127 SUPERFAMILY SSF54593 3 123 1.21E-28 T 11-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AUP74_RS14845 7816cc6736a0a60c63373dee0f687c61 127 Gene3D G3DSA:3.10.180.10 2 115 6.4E-23 T 11-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AUP74_RS14845 7816cc6736a0a60c63373dee0f687c61 127 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 107 1.9E-11 T 11-11-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AUP74_RS10150 8a834587044c94a645be565df7370435 676 Gene3D G3DSA:3.20.20.70 5 362 9.1E-125 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS10150 8a834587044c94a645be565df7370435 676 Gene3D G3DSA:3.50.50.60 363 466 1.1E-26 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS10150 8a834587044c94a645be565df7370435 676 Gene3D G3DSA:3.50.50.60 471 629 6.9E-47 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS10150 8a834587044c94a645be565df7370435 676 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 378 646 2.0E-27 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS10150 8a834587044c94a645be565df7370435 676 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 8 333 2.2E-88 T 11-11-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 AUP74_RS10150 8a834587044c94a645be565df7370435 676 SUPERFAMILY SSF51905 376 609 1.42E-42 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS10150 8a834587044c94a645be565df7370435 676 SUPERFAMILY SSF51395 2 364 4.64E-114 T 11-11-2016 AUP74_RS10150 8a834587044c94a645be565df7370435 676 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 622 638 2.7E-12 T 11-11-2016 AUP74_RS10150 8a834587044c94a645be565df7370435 676 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 379 398 2.7E-12 T 11-11-2016 AUP74_RS10150 8a834587044c94a645be565df7370435 676 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 499 517 2.7E-12 T 11-11-2016 AUP74_RS10150 8a834587044c94a645be565df7370435 676 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 623 637 1.4E-6 T 11-11-2016 AUP74_RS10150 8a834587044c94a645be565df7370435 676 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 378 400 1.4E-6 T 11-11-2016 AUP74_RS01345 4e187f98141e713410f8221db90344fe 517 SUPERFAMILY SSF56024 286 467 3.59E-35 T 11-11-2016 AUP74_RS01345 4e187f98141e713410f8221db90344fe 517 Gene3D G3DSA:3.30.870.10 307 493 4.8E-32 T 11-11-2016 AUP74_RS01345 4e187f98141e713410f8221db90344fe 517 Gene3D G3DSA:3.30.870.10 66 243 8.3E-41 T 11-11-2016 AUP74_RS01345 4e187f98141e713410f8221db90344fe 517 SMART SM00155 412 439 0.0023 T 11-11-2016 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 AUP74_RS01345 4e187f98141e713410f8221db90344fe 517 SMART SM00155 174 201 6.2E-4 T 11-11-2016 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 AUP74_RS01345 4e187f98141e713410f8221db90344fe 517 Pfam PF13091 PLD-like domain 323 464 3.9E-22 T 11-11-2016 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 AUP74_RS01345 4e187f98141e713410f8221db90344fe 517 Pfam PF13091 PLD-like domain 86 214 4.8E-18 T 11-11-2016 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 AUP74_RS01345 4e187f98141e713410f8221db90344fe 517 SUPERFAMILY SSF56024 51 244 4.04E-43 T 11-11-2016 AUP74_RS04280 6ceeff9c4a152f7f92e8941e9abc459a 267 ProSitePatterns PS00356 LacI-type HTH domain signature. 24 42 - T 11-11-2016 AUP74_RS04280 6ceeff9c4a152f7f92e8941e9abc459a 267 SUPERFAMILY SSF53697 71 265 8.09E-39 T 11-11-2016 AUP74_RS04280 6ceeff9c4a152f7f92e8941e9abc459a 267 Gene3D G3DSA:3.40.50.10490 92 252 2.8E-36 T 11-11-2016 AUP74_RS04280 6ceeff9c4a152f7f92e8941e9abc459a 267 Pfam PF01418 Helix-turn-helix domain, rpiR family 1 63 1.3E-24 T 11-11-2016 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 AUP74_RS04280 6ceeff9c4a152f7f92e8941e9abc459a 267 SUPERFAMILY SSF46689 2 63 3.58E-20 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS04280 6ceeff9c4a152f7f92e8941e9abc459a 267 Pfam PF01380 SIS domain 112 239 6.7E-20 T 11-11-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 AUP74_RS04280 6ceeff9c4a152f7f92e8941e9abc459a 267 Gene3D G3DSA:1.10.10.10 1 64 1.3E-28 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS04000 dd6ba8d498e75e5cfe4be1a65f9718ba 403 SUPERFAMILY SSF52507 1 180 1.7E-60 T 11-11-2016 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 AUP74_RS04000 dd6ba8d498e75e5cfe4be1a65f9718ba 403 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 4 396 5.8E-149 T 11-11-2016 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5 AUP74_RS04000 dd6ba8d498e75e5cfe4be1a65f9718ba 403 Gene3D G3DSA:3.40.50.10300 185 399 5.5E-87 T 11-11-2016 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 AUP74_RS04000 dd6ba8d498e75e5cfe4be1a65f9718ba 403 Pfam PF02441 Flavoprotein 7 135 2.5E-35 T 11-11-2016 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 AUP74_RS04000 dd6ba8d498e75e5cfe4be1a65f9718ba 403 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 187 372 9.3E-74 T 11-11-2016 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 AUP74_RS04000 dd6ba8d498e75e5cfe4be1a65f9718ba 403 Gene3D G3DSA:3.40.50.1950 3 183 6.3E-66 T 11-11-2016 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 AUP74_RS04000 dd6ba8d498e75e5cfe4be1a65f9718ba 403 SUPERFAMILY SSF102645 186 398 3.27E-75 T 11-11-2016 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 AUP74_RS14440 57883d3ecbdf495b5aa8f3844a2d139c 565 Pfam PF00795 Carbon-nitrogen hydrolase 3 258 4.4E-35 T 11-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AUP74_RS14440 57883d3ecbdf495b5aa8f3844a2d139c 565 Gene3D G3DSA:3.60.110.10 298 486 2.6E-14 T 11-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AUP74_RS14440 57883d3ecbdf495b5aa8f3844a2d139c 565 SUPERFAMILY SSF56317 3 277 8.63E-52 T 11-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AUP74_RS14440 57883d3ecbdf495b5aa8f3844a2d139c 565 SUPERFAMILY SSF56317 314 486 3.53E-15 T 11-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AUP74_RS14440 57883d3ecbdf495b5aa8f3844a2d139c 565 Gene3D G3DSA:3.60.110.10 2 277 4.8E-54 T 11-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AUP74_RS08735 ff98841bdbeb5721f8bb0d126bb5974c 436 Pfam PF01943 Polysaccharide biosynthesis protein 15 293 3.8E-17 T 11-11-2016 IPR002797 Polysaccharide biosynthesis protein GO:0016020 AUP74_RS08735 ff98841bdbeb5721f8bb0d126bb5974c 436 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 343 427 8.3E-8 T 11-11-2016 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain AUP74_RS02500 4282290c9ee5ebe36161c25fea6c0431 335 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 22 204 3.3E-40 T 11-11-2016 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal AUP74_RS02500 4282290c9ee5ebe36161c25fea6c0431 335 SMART SM00342 248 330 1.8E-23 T 11-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AUP74_RS02500 4282290c9ee5ebe36161c25fea6c0431 335 Pfam PF12833 Helix-turn-helix domain 254 331 1.6E-16 T 11-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AUP74_RS02500 4282290c9ee5ebe36161c25fea6c0431 335 SUPERFAMILY SSF46689 283 334 1.12E-12 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS02500 4282290c9ee5ebe36161c25fea6c0431 335 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 314 330 8.4E-7 T 11-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AUP74_RS02500 4282290c9ee5ebe36161c25fea6c0431 335 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 299 314 8.4E-7 T 11-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AUP74_RS02500 4282290c9ee5ebe36161c25fea6c0431 335 Gene3D G3DSA:1.10.10.60 283 333 4.5E-16 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 SUPERFAMILY SSF103647 113 202 1.26E-18 T 11-11-2016 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 SUPERFAMILY SSF103647 194 303 6.41E-25 T 11-11-2016 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 SUPERFAMILY SSF103647 671 788 2.09E-27 T 11-11-2016 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 SUPERFAMILY SSF103647 562 678 7.85E-22 T 11-11-2016 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 Gene3D G3DSA:4.10.1080.10 596 701 1.4E-27 T 11-11-2016 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 Gene3D G3DSA:4.10.1080.10 121 223 6.2E-27 T 11-11-2016 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 Gene3D G3DSA:4.10.1080.10 305 420 6.9E-30 T 11-11-2016 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 Gene3D G3DSA:4.10.1080.10 770 879 1.3E-30 T 11-11-2016 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 Gene3D G3DSA:4.10.1080.10 224 304 2.5E-19 T 11-11-2016 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 Gene3D G3DSA:4.10.1080.10 39 120 2.2E-22 T 11-11-2016 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 Gene3D G3DSA:4.10.1080.10 479 595 1.5E-29 T 11-11-2016 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 SUPERFAMILY SSF103647 780 878 1.57E-24 T 11-11-2016 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 Pfam PF02412 Thrombospondin type 3 repeat 683 719 2.0E-8 T 11-11-2016 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 Pfam PF02412 Thrombospondin type 3 repeat 610 645 6.8E-11 T 11-11-2016 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 Pfam PF02412 Thrombospondin type 3 repeat 465 501 2.8E-7 T 11-11-2016 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 Pfam PF02412 Thrombospondin type 3 repeat 793 827 2.4E-9 T 11-11-2016 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 Pfam PF02412 Thrombospondin type 3 repeat 539 573 2.7E-8 T 11-11-2016 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 Pfam PF02412 Thrombospondin type 3 repeat 647 681 1.2E-7 T 11-11-2016 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 Pfam PF02412 Thrombospondin type 3 repeat 393 427 5.8E-6 T 11-11-2016 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 Pfam PF02412 Thrombospondin type 3 repeat 99 134 1.3E-8 T 11-11-2016 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 Pfam PF02412 Thrombospondin type 3 repeat 577 609 1.6E-9 T 11-11-2016 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 Pfam PF02412 Thrombospondin type 3 repeat 172 206 4.8E-9 T 11-11-2016 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 Pfam PF02412 Thrombospondin type 3 repeat 503 537 2.8E-11 T 11-11-2016 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 Pfam PF02412 Thrombospondin type 3 repeat 40 62 1.4E-4 T 11-11-2016 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 Pfam PF02412 Thrombospondin type 3 repeat 318 355 2.3E-10 T 11-11-2016 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 Pfam PF02412 Thrombospondin type 3 repeat 721 755 9.8E-10 T 11-11-2016 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 Pfam PF02412 Thrombospondin type 3 repeat 63 98 1.9E-9 T 11-11-2016 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 Pfam PF02412 Thrombospondin type 3 repeat 281 317 2.3E-9 T 11-11-2016 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 Pfam PF02412 Thrombospondin type 3 repeat 756 791 1.8E-11 T 11-11-2016 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 Pfam PF02412 Thrombospondin type 3 repeat 429 463 1.0E-10 T 11-11-2016 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 Pfam PF02412 Thrombospondin type 3 repeat 829 863 1.7E-11 T 11-11-2016 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 Pfam PF02412 Thrombospondin type 3 repeat 357 391 2.2E-9 T 11-11-2016 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 Pfam PF02412 Thrombospondin type 3 repeat 135 170 2.0E-10 T 11-11-2016 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 Pfam PF02412 Thrombospondin type 3 repeat 208 244 4.4E-7 T 11-11-2016 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 Pfam PF02412 Thrombospondin type 3 repeat 246 280 5.9E-10 T 11-11-2016 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 SUPERFAMILY SSF103647 306 421 2.88E-27 T 11-11-2016 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 SUPERFAMILY SSF103647 38 127 1.83E-20 T 11-11-2016 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 AUP74_RS10010 5e606f43c2fd5df7094a0d370979c4ba 1043 SUPERFAMILY SSF103647 453 570 5.23E-26 T 11-11-2016 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 AUP74_RS16760 88dd55b85c76dd8f82318ebbfc8dfe96 502 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 6 489 35.256 T 11-11-2016 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 AUP74_RS16760 88dd55b85c76dd8f82318ebbfc8dfe96 502 Gene3D G3DSA:3.40.1190.10 103 339 2.8E-77 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AUP74_RS16760 88dd55b85c76dd8f82318ebbfc8dfe96 502 SUPERFAMILY SSF63418 16 100 1.7E-22 T 11-11-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 AUP74_RS16760 88dd55b85c76dd8f82318ebbfc8dfe96 502 Pfam PF02875 Mur ligase family, glutamate ligase domain 336 424 6.6E-24 T 11-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AUP74_RS16760 88dd55b85c76dd8f82318ebbfc8dfe96 502 SUPERFAMILY SSF53623 102 333 2.88E-72 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AUP74_RS16760 88dd55b85c76dd8f82318ebbfc8dfe96 502 Pfam PF08245 Mur ligase middle domain 111 316 2.8E-51 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AUP74_RS16760 88dd55b85c76dd8f82318ebbfc8dfe96 502 SUPERFAMILY SSF53244 336 491 7.2E-51 T 11-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AUP74_RS16760 88dd55b85c76dd8f82318ebbfc8dfe96 502 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 20 489 9.9E-160 T 11-11-2016 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 AUP74_RS16760 88dd55b85c76dd8f82318ebbfc8dfe96 502 Gene3D G3DSA:3.40.1390.10 15 100 5.5E-26 T 11-11-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 AUP74_RS16760 88dd55b85c76dd8f82318ebbfc8dfe96 502 Gene3D G3DSA:3.90.190.20 340 483 1.9E-58 T 11-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AUP74_RS16760 88dd55b85c76dd8f82318ebbfc8dfe96 502 Pfam PF01225 Mur ligase family, catalytic domain 22 99 1.5E-13 T 11-11-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 AUP74_RS12990 1bb21c83d870bee4e0fa921b2928dd1b 336 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 320 7.9E-38 T 11-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme AUP74_RS12990 1bb21c83d870bee4e0fa921b2928dd1b 336 SUPERFAMILY SSF53686 9 330 7.82E-69 T 11-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme AUP74_RS12990 1bb21c83d870bee4e0fa921b2928dd1b 336 PIRSF PIRSF006278 1 335 3.9E-82 T 11-11-2016 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase AUP74_RS12990 1bb21c83d870bee4e0fa921b2928dd1b 336 Gene3D G3DSA:3.40.50.1100 92 330 9.3E-56 T 11-11-2016 AUP74_RS10875 33f044fdd6870a1ffa0ecc994deb5906 225 SUPERFAMILY SSF52540 9 202 1.41E-33 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS10875 33f044fdd6870a1ffa0ecc994deb5906 225 Gene3D G3DSA:3.40.50.300 12 201 4.3E-33 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS10875 33f044fdd6870a1ffa0ecc994deb5906 225 SMART SM00382 35 209 1.9E-6 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS10875 33f044fdd6870a1ffa0ecc994deb5906 225 TIGRFAM TIGR01189 ccmA: heme ABC exporter, ATP-binding protein CcmA 11 202 2.3E-62 T 11-11-2016 IPR005895 ABC transporter, haem export, CcmA GO:0005215|GO:0017004|GO:0030288 AUP74_RS10875 33f044fdd6870a1ffa0ecc994deb5906 225 Pfam PF00005 ABC transporter 28 163 6.7E-24 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AUP74_RS08910 3f8b6df6b0393abd840c7a2463327eaf 365 SUPERFAMILY SSF51735 1 342 8.0E-89 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS08910 3f8b6df6b0393abd840c7a2463327eaf 365 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 329 1.2E-91 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS08910 3f8b6df6b0393abd840c7a2463327eaf 365 Gene3D G3DSA:3.90.25.10 196 342 2.9E-51 T 11-11-2016 AUP74_RS08910 3f8b6df6b0393abd840c7a2463327eaf 365 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 343 2.2E-143 T 11-11-2016 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 AUP74_RS08910 3f8b6df6b0393abd840c7a2463327eaf 365 Gene3D G3DSA:3.40.50.720 1 195 2.1E-63 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS01700 f44aa3a077a1ddaeb0f82a4895b31262 464 TIGRFAM TIGR00416 sms: DNA repair protein RadA 2 458 4.4E-211 T 11-11-2016 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 AUP74_RS01700 f44aa3a077a1ddaeb0f82a4895b31262 464 SMART SM00382 98 251 3.0E-9 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS01700 f44aa3a077a1ddaeb0f82a4895b31262 464 SUPERFAMILY SSF54211 262 276 1.37E-41 T 11-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold AUP74_RS01700 f44aa3a077a1ddaeb0f82a4895b31262 464 SUPERFAMILY SSF54211 310 460 1.37E-41 T 11-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold AUP74_RS01700 f44aa3a077a1ddaeb0f82a4895b31262 464 Pfam PF13541 Subunit ChlI of Mg-chelatase 358 437 7.2E-8 T 11-11-2016 AUP74_RS01700 f44aa3a077a1ddaeb0f82a4895b31262 464 Hamap MF_01498 DNA repair protein RadA [radA]. 22 462 42.646 T 11-11-2016 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 AUP74_RS01700 f44aa3a077a1ddaeb0f82a4895b31262 464 PRINTS PR01874 DNA repair protein radA signature 90 118 1.8E-93 T 11-11-2016 AUP74_RS01700 f44aa3a077a1ddaeb0f82a4895b31262 464 PRINTS PR01874 DNA repair protein radA signature 255 281 1.8E-93 T 11-11-2016 AUP74_RS01700 f44aa3a077a1ddaeb0f82a4895b31262 464 PRINTS PR01874 DNA repair protein radA signature 11 35 1.8E-93 T 11-11-2016 AUP74_RS01700 f44aa3a077a1ddaeb0f82a4895b31262 464 PRINTS PR01874 DNA repair protein radA signature 131 148 1.8E-93 T 11-11-2016 AUP74_RS01700 f44aa3a077a1ddaeb0f82a4895b31262 464 PRINTS PR01874 DNA repair protein radA signature 329 352 1.8E-93 T 11-11-2016 AUP74_RS01700 f44aa3a077a1ddaeb0f82a4895b31262 464 PRINTS PR01874 DNA repair protein radA signature 181 205 1.8E-93 T 11-11-2016 AUP74_RS01700 f44aa3a077a1ddaeb0f82a4895b31262 464 PRINTS PR01874 DNA repair protein radA signature 220 248 1.8E-93 T 11-11-2016 AUP74_RS01700 f44aa3a077a1ddaeb0f82a4895b31262 464 Gene3D G3DSA:3.30.230.10 292 460 1.7E-37 T 11-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AUP74_RS01700 f44aa3a077a1ddaeb0f82a4895b31262 464 SUPERFAMILY SSF52540 76 294 1.78E-46 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS01700 f44aa3a077a1ddaeb0f82a4895b31262 464 Pfam PF13481 AAA domain 81 229 2.7E-13 T 11-11-2016 AUP74_RS01700 f44aa3a077a1ddaeb0f82a4895b31262 464 Gene3D G3DSA:3.40.50.300 66 284 3.1E-51 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS12155 8a7de10175fe83ac586e3d078e5a776e 282 ProSitePatterns PS01245 RIO1/ZK632.3/MJ0444 family signature. 164 175 - T 11-11-2016 IPR018935 RIO kinase, conserved site GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|Reactome: R-HSA-6791226 AUP74_RS12155 8a7de10175fe83ac586e3d078e5a776e 282 SUPERFAMILY SSF56112 18 222 9.37E-23 T 11-11-2016 IPR011009 Protein kinase-like domain AUP74_RS12155 8a7de10175fe83ac586e3d078e5a776e 282 Gene3D G3DSA:1.10.510.10 139 220 1.2E-21 T 11-11-2016 AUP74_RS12155 8a7de10175fe83ac586e3d078e5a776e 282 Gene3D G3DSA:3.30.200.20 17 125 1.9E-11 T 11-11-2016 AUP74_RS12155 8a7de10175fe83ac586e3d078e5a776e 282 SMART SM00090 5 234 4.6E-18 T 11-11-2016 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|Reactome: R-HSA-6791226 AUP74_RS12155 8a7de10175fe83ac586e3d078e5a776e 282 Pfam PF01163 RIO1 family 31 222 4.8E-44 T 11-11-2016 AUP74_RS04065 09cf0785c55e37c3caeb65c0314c8387 334 SUPERFAMILY SSF51735 139 300 1.62E-42 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS04065 09cf0785c55e37c3caeb65c0314c8387 334 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 134 6.5E-27 T 11-11-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AUP74_RS04065 09cf0785c55e37c3caeb65c0314c8387 334 Gene3D G3DSA:3.90.180.10 2 170 2.3E-57 T 11-11-2016 IPR011032 GroES-like AUP74_RS04065 09cf0785c55e37c3caeb65c0314c8387 334 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 168 195 - T 11-11-2016 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 AUP74_RS04065 09cf0785c55e37c3caeb65c0314c8387 334 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 11-11-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 AUP74_RS04065 09cf0785c55e37c3caeb65c0314c8387 334 SUPERFAMILY SSF50129 4 159 9.75E-45 T 11-11-2016 IPR011032 GroES-like AUP74_RS04065 09cf0785c55e37c3caeb65c0314c8387 334 SMART SM00829 12 330 6.5E-8 T 11-11-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AUP74_RS04065 09cf0785c55e37c3caeb65c0314c8387 334 Pfam PF00107 Zinc-binding dehydrogenase 175 296 7.3E-24 T 11-11-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AUP74_RS04065 09cf0785c55e37c3caeb65c0314c8387 334 Gene3D G3DSA:3.40.50.720 171 280 7.5E-23 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS13295 aeec88dc516d51a5f23730e28399e9c3 674 SUPERFAMILY SSF53474 5 338 8.69E-74 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS13295 aeec88dc516d51a5f23730e28399e9c3 674 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 304 546 8.4E-49 T 11-11-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 AUP74_RS13295 aeec88dc516d51a5f23730e28399e9c3 674 SUPERFAMILY SSF49785 376 531 1.3E-53 T 11-11-2016 IPR008979 Galactose-binding domain-like AUP74_RS13295 aeec88dc516d51a5f23730e28399e9c3 674 SUPERFAMILY SSF49785 291 341 1.3E-53 T 11-11-2016 IPR008979 Galactose-binding domain-like AUP74_RS13295 aeec88dc516d51a5f23730e28399e9c3 674 Gene3D G3DSA:3.40.50.1820 218 331 9.3E-73 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS13295 aeec88dc516d51a5f23730e28399e9c3 674 Gene3D G3DSA:3.40.50.1820 7 159 9.3E-73 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS13295 aeec88dc516d51a5f23730e28399e9c3 674 SMART SM00939 291 549 1.1E-80 T 11-11-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 AUP74_RS13295 aeec88dc516d51a5f23730e28399e9c3 674 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 23 504 1.2E-63 T 11-11-2016 IPR005674 CocE/Serine esterase GO:0016787 AUP74_RS13295 aeec88dc516d51a5f23730e28399e9c3 674 Gene3D G3DSA:2.60.120.260 332 531 3.7E-51 T 11-11-2016 IPR008979 Galactose-binding domain-like AUP74_RS13295 aeec88dc516d51a5f23730e28399e9c3 674 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 23 274 3.9E-61 T 11-11-2016 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 AUP74_RS02355 7138e5a76a8c4973abadeaaef2ae275a 273 Pfam PF05742 Transport and Golgi organisation 2 1 257 8.0E-57 T 11-11-2016 IPR008551 Transport and Golgi organisation protein 2 AUP74_RS12780 7b2ae7de82cf2a25fd6aea17dc04c418 429 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 106 5.4E-30 T 11-11-2016 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AUP74_RS12780 7b2ae7de82cf2a25fd6aea17dc04c418 429 PRINTS PR00981 Seryl-tRNA synthetase signature 352 368 1.8E-30 T 11-11-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AUP74_RS12780 7b2ae7de82cf2a25fd6aea17dc04c418 429 PRINTS PR00981 Seryl-tRNA synthetase signature 277 290 1.8E-30 T 11-11-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AUP74_RS12780 7b2ae7de82cf2a25fd6aea17dc04c418 429 PRINTS PR00981 Seryl-tRNA synthetase signature 317 330 1.8E-30 T 11-11-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AUP74_RS12780 7b2ae7de82cf2a25fd6aea17dc04c418 429 PRINTS PR00981 Seryl-tRNA synthetase signature 265 277 1.8E-30 T 11-11-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AUP74_RS12780 7b2ae7de82cf2a25fd6aea17dc04c418 429 PRINTS PR00981 Seryl-tRNA synthetase signature 334 350 1.8E-30 T 11-11-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AUP74_RS12780 7b2ae7de82cf2a25fd6aea17dc04c418 429 Gene3D G3DSA:1.10.287.40 1 104 3.3E-27 T 11-11-2016 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AUP74_RS12780 7b2ae7de82cf2a25fd6aea17dc04c418 429 Gene3D G3DSA:3.30.930.10 105 422 2.2E-136 T 11-11-2016 AUP74_RS12780 7b2ae7de82cf2a25fd6aea17dc04c418 429 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 218 401 4.4E-36 T 11-11-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS12780 7b2ae7de82cf2a25fd6aea17dc04c418 429 SUPERFAMILY SSF55681 116 419 9.21E-99 T 11-11-2016 AUP74_RS12780 7b2ae7de82cf2a25fd6aea17dc04c418 429 SUPERFAMILY SSF46589 1 112 2.3E-29 T 11-11-2016 IPR010978 tRNA-binding arm GO:0000166 AUP74_RS12780 7b2ae7de82cf2a25fd6aea17dc04c418 429 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 423 40.583 T 11-11-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AUP74_RS12780 7b2ae7de82cf2a25fd6aea17dc04c418 429 PIRSF PIRSF001529 1 427 2.5E-178 T 11-11-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AUP74_RS12780 7b2ae7de82cf2a25fd6aea17dc04c418 429 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 418 9.6E-168 T 11-11-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AUP74_RS04150 ca41360b10355b608f363d8a4d5a437b 234 Gene3D G3DSA:3.40.50.2300 2 124 3.9E-43 T 11-11-2016 AUP74_RS04150 ca41360b10355b608f363d8a4d5a437b 234 TIGRFAM TIGR02154 PhoB: phosphate regulon transcriptional regulatory protein PhoB 3 227 2.1E-107 T 11-11-2016 IPR011879 Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB GO:0000156|GO:0000160|GO:0003677|GO:0006817 AUP74_RS04150 ca41360b10355b608f363d8a4d5a437b 234 Pfam PF00072 Response regulator receiver domain 6 117 2.3E-30 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS04150 ca41360b10355b608f363d8a4d5a437b 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 226 6.2E-26 T 11-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AUP74_RS04150 ca41360b10355b608f363d8a4d5a437b 234 SUPERFAMILY SSF52172 1 185 1.76E-44 T 11-11-2016 IPR011006 CheY-like superfamily AUP74_RS04150 ca41360b10355b608f363d8a4d5a437b 234 SMART SM00448 4 117 6.4E-46 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS04150 ca41360b10355b608f363d8a4d5a437b 234 Gene3D G3DSA:1.10.10.10 129 229 5.1E-35 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS04150 ca41360b10355b608f363d8a4d5a437b 234 SMART SM00862 151 226 2.9E-26 T 11-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AUP74_RS00945 44c67ab27a54c1a4814b3eac06395f31 176 SUPERFAMILY SSF53098 3 157 5.31E-50 T 11-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 AUP74_RS00945 44c67ab27a54c1a4814b3eac06395f31 176 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 4 158 1.1E-57 T 11-11-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 AUP74_RS00945 44c67ab27a54c1a4814b3eac06395f31 176 Gene3D G3DSA:3.30.420.10 3 157 8.9E-63 T 11-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 AUP74_RS00945 44c67ab27a54c1a4814b3eac06395f31 176 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 113 147 - T 11-11-2016 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 AUP74_RS00945 44c67ab27a54c1a4814b3eac06395f31 176 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 4 150 3.7E-56 T 11-11-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 AUP74_RS00945 44c67ab27a54c1a4814b3eac06395f31 176 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 2 153 44.303 T 11-11-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 AUP74_RS00945 44c67ab27a54c1a4814b3eac06395f31 176 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 83 99 1.7E-37 T 11-11-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 AUP74_RS00945 44c67ab27a54c1a4814b3eac06395f31 176 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 107 126 1.7E-37 T 11-11-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 AUP74_RS00945 44c67ab27a54c1a4814b3eac06395f31 176 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 138 150 1.7E-37 T 11-11-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 AUP74_RS00945 44c67ab27a54c1a4814b3eac06395f31 176 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 61 77 1.7E-37 T 11-11-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 AUP74_RS00945 44c67ab27a54c1a4814b3eac06395f31 176 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 5 18 1.7E-37 T 11-11-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 AUP74_RS01655 b5f73ee247720ca44e7412c2be6dd75d 233 Pfam PF00117 Glutamine amidotransferase class-I 75 188 4.2E-16 T 11-11-2016 IPR017926 Glutamine amidotransferase AUP74_RS01655 b5f73ee247720ca44e7412c2be6dd75d 233 SUPERFAMILY SSF52317 14 195 1.58E-40 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS01655 b5f73ee247720ca44e7412c2be6dd75d 233 Gene3D G3DSA:3.40.50.880 20 219 3.4E-45 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS12205 b00819dbcad62afa85245fdfec6616c2 609 Gene3D G3DSA:1.20.1560.10 19 354 8.3E-63 T 11-11-2016 AUP74_RS12205 b00819dbcad62afa85245fdfec6616c2 609 Pfam PF00664 ABC transporter transmembrane region 70 314 3.8E-41 T 11-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 AUP74_RS12205 b00819dbcad62afa85245fdfec6616c2 609 Gene3D G3DSA:3.40.50.300 368 600 1.3E-83 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS12205 b00819dbcad62afa85245fdfec6616c2 609 Pfam PF00005 ABC transporter 386 536 3.0E-35 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AUP74_RS12205 b00819dbcad62afa85245fdfec6616c2 609 ProSitePatterns PS00211 ABC transporters family signature. 508 522 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AUP74_RS12205 b00819dbcad62afa85245fdfec6616c2 609 TIGRFAM TIGR02203 MsbA_lipidA: lipid A export permease/ATP-binding protein MsbA 17 606 2.3E-206 T 11-11-2016 IPR011917 ABC transporter, lipid A export, MsbA GO:0005524|GO:0016021|GO:0034040 AUP74_RS12205 b00819dbcad62afa85245fdfec6616c2 609 SMART SM00382 395 582 1.5E-20 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS12205 b00819dbcad62afa85245fdfec6616c2 609 SUPERFAMILY SSF52540 361 606 2.24E-92 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS12205 b00819dbcad62afa85245fdfec6616c2 609 SUPERFAMILY SSF90123 14 354 1.57E-64 T 11-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 AUP74_RS16705 dcb0247ab96ce9f71718caeb5b193756 312 Pfam PF01551 Peptidase family M23 210 303 5.6E-34 T 11-11-2016 IPR016047 Peptidase M23 AUP74_RS16705 dcb0247ab96ce9f71718caeb5b193756 312 Gene3D G3DSA:2.70.70.10 171 308 5.7E-50 T 11-11-2016 AUP74_RS16705 dcb0247ab96ce9f71718caeb5b193756 312 SUPERFAMILY SSF51261 177 307 4.97E-58 T 11-11-2016 IPR011055 Duplicated hybrid motif AUP74_RS04035 19ccec9934d375f5f89f459531a1bc1a 239 ProSitePatterns PS01277 Ribonuclease PH signature. 117 130 - T 11-11-2016 IPR018336 Ribonuclease PH, conserved site AUP74_RS04035 19ccec9934d375f5f89f459531a1bc1a 239 SUPERFAMILY SSF55666 153 238 2.62E-25 T 11-11-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AUP74_RS04035 19ccec9934d375f5f89f459531a1bc1a 239 Hamap MF_00564 Ribonuclease PH [rph]. 2 238 48.718 T 11-11-2016 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 AUP74_RS04035 19ccec9934d375f5f89f459531a1bc1a 239 Pfam PF01138 3' exoribonuclease family, domain 1 11 141 6.2E-25 T 11-11-2016 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AUP74_RS04035 19ccec9934d375f5f89f459531a1bc1a 239 Pfam PF03725 3' exoribonuclease family, domain 2 159 225 2.2E-11 T 11-11-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AUP74_RS04035 19ccec9934d375f5f89f459531a1bc1a 239 SUPERFAMILY SSF54211 3 182 2.58E-45 T 11-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold AUP74_RS04035 19ccec9934d375f5f89f459531a1bc1a 239 Gene3D G3DSA:3.30.230.70 11 238 3.6E-33 T 11-11-2016 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AUP74_RS04035 19ccec9934d375f5f89f459531a1bc1a 239 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 3 237 2.1E-116 T 11-11-2016 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 AUP74_RS07290 e16bcb59cbf23713ef4708a2c9b2bdaa 408 SUPERFAMILY SSF53335 210 334 9.46E-8 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS07290 e16bcb59cbf23713ef4708a2c9b2bdaa 408 Gene3D G3DSA:3.40.50.150 15 174 7.4E-4 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS07290 e16bcb59cbf23713ef4708a2c9b2bdaa 408 SUPERFAMILY SSF53335 15 147 1.83E-8 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS07290 e16bcb59cbf23713ef4708a2c9b2bdaa 408 Gene3D G3DSA:3.40.50.150 221 374 4.0E-6 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS12470 c82bb6be613ae2ef4222c96925aed766 388 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 34 368 2.8E-86 T 11-11-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 AUP74_RS12470 c82bb6be613ae2ef4222c96925aed766 388 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 55 286 1.5E-15 T 11-11-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AUP74_RS12470 c82bb6be613ae2ef4222c96925aed766 388 SUPERFAMILY SSF111369 45 293 1.57E-78 T 11-11-2016 AUP74_RS12470 c82bb6be613ae2ef4222c96925aed766 388 Gene3D G3DSA:2.40.50.100 59 92 3.5E-20 T 11-11-2016 AUP74_RS12470 c82bb6be613ae2ef4222c96925aed766 388 Gene3D G3DSA:2.40.50.100 167 202 3.5E-20 T 11-11-2016 AUP74_RS12470 c82bb6be613ae2ef4222c96925aed766 388 Pfam PF00529 HlyD membrane-fusion protein of T1SS 196 353 1.6E-6 T 11-11-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 AUP74_RS12840 13230f671c18d2f5127c36ff6798650c 416 SUPERFAMILY SSF53659 4 415 6.14E-144 T 11-11-2016 AUP74_RS12840 13230f671c18d2f5127c36ff6798650c 416 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 29 411 6.7E-115 T 11-11-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AUP74_RS12840 13230f671c18d2f5127c36ff6798650c 416 SMART SM01329 28 411 1.1E-178 T 11-11-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AUP74_RS12840 13230f671c18d2f5127c36ff6798650c 416 Gene3D G3DSA:3.40.718.10 11 415 1.1E-162 T 11-11-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AUP74_RS12840 13230f671c18d2f5127c36ff6798650c 416 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 302 321 - T 11-11-2016 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 AUP74_RS12840 13230f671c18d2f5127c36ff6798650c 416 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 3 415 1.4E-220 T 11-11-2016 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 AUP74_RS07865 83cf9cf146fafd6eff86f23e556cf50b 284 Pfam PF13145 PPIC-type PPIASE domain 116 239 4.4E-10 T 11-11-2016 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 AUP74_RS07865 83cf9cf146fafd6eff86f23e556cf50b 284 SUPERFAMILY SSF54534 130 227 9.16E-5 T 11-11-2016 AUP74_RS07865 83cf9cf146fafd6eff86f23e556cf50b 284 Gene3D G3DSA:3.10.50.40 195 250 2.2E-9 T 11-11-2016 AUP74_RS13230 aa39e23f6ac1fec843535cafa640b8c2 213 PIRSF PIRSF023956 1 213 2.9E-74 T 11-11-2016 IPR025835 Thiopurine S-methyltransferase GO:0008119 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581|Reactome: R-HSA-5578995 AUP74_RS13230 aa39e23f6ac1fec843535cafa640b8c2 213 Gene3D G3DSA:3.40.50.150 16 197 1.8E-51 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS13230 aa39e23f6ac1fec843535cafa640b8c2 213 TIGRFAM TIGR03840 TMPT_Se_Te: thiopurine S-methyltransferase, Se/Te detoxification family 4 209 2.2E-76 T 11-11-2016 IPR022474 Thiopurine S-methyltransferase, Se/Te detoxification GO:0008119|GO:0010038|GO:0032259 KEGG: 00983+2.1.1.67 AUP74_RS13230 aa39e23f6ac1fec843535cafa640b8c2 213 Hamap MF_00812 Thiopurine S-methyltransferase [tpm]. 1 211 37.59 T 11-11-2016 IPR025835 Thiopurine S-methyltransferase GO:0008119 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581|Reactome: R-HSA-5578995 AUP74_RS13230 aa39e23f6ac1fec843535cafa640b8c2 213 SUPERFAMILY SSF53335 1 190 7.39E-50 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS13230 aa39e23f6ac1fec843535cafa640b8c2 213 Pfam PF05724 Thiopurine S-methyltransferase (TPMT) 1 191 4.2E-59 T 11-11-2016 IPR008854 TPMT family GO:0008757 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581|Reactome: R-HSA-5578995 AUP74_RS09140 94e0719d7f2606bc441a95c60ca82e8a 142 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 2.5E-42 T 11-11-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AUP74_RS09140 94e0719d7f2606bc441a95c60ca82e8a 142 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 2.5E-42 T 11-11-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AUP74_RS09140 94e0719d7f2606bc441a95c60ca82e8a 142 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 2.5E-42 T 11-11-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AUP74_RS09140 94e0719d7f2606bc441a95c60ca82e8a 142 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 2.5E-42 T 11-11-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AUP74_RS09140 94e0719d7f2606bc441a95c60ca82e8a 142 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 2.5E-42 T 11-11-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AUP74_RS09140 94e0719d7f2606bc441a95c60ca82e8a 142 SUPERFAMILY SSF54919 1 140 4.32E-61 T 11-11-2016 AUP74_RS09140 94e0719d7f2606bc441a95c60ca82e8a 142 SMART SM00562 3 140 2.1E-91 T 11-11-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AUP74_RS09140 94e0719d7f2606bc441a95c60ca82e8a 142 Gene3D G3DSA:3.30.70.141 1 140 2.3E-62 T 11-11-2016 AUP74_RS09140 94e0719d7f2606bc441a95c60ca82e8a 142 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 37.219 T 11-11-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AUP74_RS09140 94e0719d7f2606bc441a95c60ca82e8a 142 Pfam PF00334 Nucleoside diphosphate kinase 4 138 1.9E-59 T 11-11-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AUP74_RS13550 f8d4665b2cd76cd5539589e09f5ec693 601 TIGRFAM TIGR01480 copper_res_A: copper-resistance protein, CopA family 15 600 1.8E-209 T 11-11-2016 IPR006376 Copper-resistance protein CopA GO:0005507|GO:0042597 AUP74_RS13550 f8d4665b2cd76cd5539589e09f5ec693 601 Pfam PF07731 Multicopper oxidase 490 600 4.6E-20 T 11-11-2016 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 AUP74_RS13550 f8d4665b2cd76cd5539589e09f5ec693 601 Gene3D G3DSA:2.60.40.420 187 394 1.7E-42 T 11-11-2016 IPR008972 Cupredoxin AUP74_RS13550 f8d4665b2cd76cd5539589e09f5ec693 601 Pfam PF00394 Multicopper oxidase 264 365 1.4E-23 T 11-11-2016 IPR001117 Multicopper oxidase, type 1 GO:0016491|GO:0055114 AUP74_RS13550 f8d4665b2cd76cd5539589e09f5ec693 601 Gene3D G3DSA:2.60.40.420 475 600 8.6E-28 T 11-11-2016 IPR008972 Cupredoxin AUP74_RS13550 f8d4665b2cd76cd5539589e09f5ec693 601 SUPERFAMILY SSF49503 185 402 7.79E-47 T 11-11-2016 IPR008972 Cupredoxin AUP74_RS13550 f8d4665b2cd76cd5539589e09f5ec693 601 Pfam PF07732 Multicopper oxidase 70 181 3.6E-38 T 11-11-2016 IPR011707 Multicopper oxidase, type 3 GO:0005507 AUP74_RS13550 f8d4665b2cd76cd5539589e09f5ec693 601 ProSitePatterns PS00080 Multicopper oxidases signature 2. 583 594 - T 11-11-2016 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 AUP74_RS13550 f8d4665b2cd76cd5539589e09f5ec693 601 SUPERFAMILY SSF49503 444 600 4.02E-28 T 11-11-2016 IPR008972 Cupredoxin AUP74_RS13550 f8d4665b2cd76cd5539589e09f5ec693 601 SUPERFAMILY SSF49503 33 207 1.77E-38 T 11-11-2016 IPR008972 Cupredoxin AUP74_RS13550 f8d4665b2cd76cd5539589e09f5ec693 601 Gene3D G3DSA:2.60.40.420 56 179 3.8E-31 T 11-11-2016 IPR008972 Cupredoxin AUP74_RS16855 51d0c78ef2d50e5327102a8560e2935c 733 PRINTS PR00603 Cytochrome C1 signature 697 712 2.7E-10 T 11-11-2016 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 AUP74_RS16855 51d0c78ef2d50e5327102a8560e2935c 733 PRINTS PR00603 Cytochrome C1 signature 519 538 2.7E-10 T 11-11-2016 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 AUP74_RS16855 51d0c78ef2d50e5327102a8560e2935c 733 PRINTS PR00603 Cytochrome C1 signature 581 605 2.7E-10 T 11-11-2016 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 AUP74_RS16855 51d0c78ef2d50e5327102a8560e2935c 733 PRINTS PR00603 Cytochrome C1 signature 678 697 2.7E-10 T 11-11-2016 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 AUP74_RS16855 51d0c78ef2d50e5327102a8560e2935c 733 Pfam PF02167 Cytochrome C1 family 580 731 1.4E-12 T 11-11-2016 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 AUP74_RS16855 51d0c78ef2d50e5327102a8560e2935c 733 SUPERFAMILY SSF81342 9 282 1.88E-91 T 11-11-2016 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 AUP74_RS16855 51d0c78ef2d50e5327102a8560e2935c 733 SUPERFAMILY SSF81648 283 403 2.83E-27 T 11-11-2016 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 AUP74_RS16855 51d0c78ef2d50e5327102a8560e2935c 733 SUPERFAMILY SSF46626 673 696 5.3E-42 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS16855 51d0c78ef2d50e5327102a8560e2935c 733 SUPERFAMILY SSF46626 495 636 5.3E-42 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS16855 51d0c78ef2d50e5327102a8560e2935c 733 Pfam PF00033 Cytochrome b/b6/petB 27 214 4.2E-64 T 11-11-2016 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 AUP74_RS16855 51d0c78ef2d50e5327102a8560e2935c 733 Gene3D G3DSA:1.10.760.10 493 697 2.4E-57 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS16855 51d0c78ef2d50e5327102a8560e2935c 733 Gene3D G3DSA:1.20.810.10 9 406 4.3E-153 T 11-11-2016 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 AUP74_RS16855 51d0c78ef2d50e5327102a8560e2935c 733 Gene3D G3DSA:1.20.5.100 700 733 1.7E-10 T 11-11-2016 AUP74_RS16855 51d0c78ef2d50e5327102a8560e2935c 733 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 280 389 2.0E-40 T 11-11-2016 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 AUP74_RS01270 22871ef4e7d617e0c05b4024d0c6875a 737 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 125 448 1.4E-100 T 11-11-2016 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 AUP74_RS01270 22871ef4e7d617e0c05b4024d0c6875a 737 SUPERFAMILY SSF82171 19 471 4.97E-70 T 11-11-2016 AUP74_RS01270 22871ef4e7d617e0c05b4024d0c6875a 737 SUPERFAMILY SSF53474 484 734 3.16E-82 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS01270 22871ef4e7d617e0c05b4024d0c6875a 737 Gene3D G3DSA:3.40.50.1820 484 734 4.1E-94 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS01270 22871ef4e7d617e0c05b4024d0c6875a 737 Pfam PF00326 Prolyl oligopeptidase family 539 735 1.8E-59 T 11-11-2016 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 AUP74_RS01270 22871ef4e7d617e0c05b4024d0c6875a 737 Gene3D G3DSA:2.140.10.30 20 469 1.3E-127 T 11-11-2016 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 AUP74_RS00230 7a4b8848b6926a198c9ad7884ea25b82 514 PIRSF PIRSF011396 1 504 2.1E-132 T 11-11-2016 IPR006905 Tryptophan halogenase AUP74_RS00230 7a4b8848b6926a198c9ad7884ea25b82 514 Gene3D G3DSA:3.50.50.60 161 238 4.1E-43 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS00230 7a4b8848b6926a198c9ad7884ea25b82 514 Gene3D G3DSA:3.50.50.60 323 367 4.1E-43 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS00230 7a4b8848b6926a198c9ad7884ea25b82 514 Gene3D G3DSA:3.50.50.60 9 78 4.1E-43 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS00230 7a4b8848b6926a198c9ad7884ea25b82 514 SUPERFAMILY SSF51905 328 413 4.23E-31 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS00230 7a4b8848b6926a198c9ad7884ea25b82 514 SUPERFAMILY SSF51905 11 93 4.23E-31 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS00230 7a4b8848b6926a198c9ad7884ea25b82 514 SUPERFAMILY SSF51905 157 239 4.23E-31 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS00230 7a4b8848b6926a198c9ad7884ea25b82 514 Pfam PF04820 Tryptophan halogenase 9 464 1.3E-122 T 11-11-2016 IPR006905 Tryptophan halogenase AUP74_RS12930 0937ab5e664b181355657427fd17ebea 175 Pfam PF03734 L,D-transpeptidase catalytic domain 37 173 1.2E-22 T 11-11-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 AUP74_RS12930 0937ab5e664b181355657427fd17ebea 175 Gene3D G3DSA:2.40.440.10 32 80 7.8E-21 T 11-11-2016 AUP74_RS12930 0937ab5e664b181355657427fd17ebea 175 Gene3D G3DSA:2.40.440.10 115 173 7.8E-21 T 11-11-2016 AUP74_RS12930 0937ab5e664b181355657427fd17ebea 175 SUPERFAMILY SSF141523 34 173 1.7E-29 T 11-11-2016 AUP74_RS15255 15ca16bbd5a65e7696dbc0552fbdab6e 1444 SMART SM00028 822 855 0.11 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS15255 15ca16bbd5a65e7696dbc0552fbdab6e 1444 SMART SM00028 788 821 1.5 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS15255 15ca16bbd5a65e7696dbc0552fbdab6e 1444 SMART SM00028 1023 1056 96.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS15255 15ca16bbd5a65e7696dbc0552fbdab6e 1444 SMART SM00028 618 651 98.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS15255 15ca16bbd5a65e7696dbc0552fbdab6e 1444 SMART SM00028 551 584 77.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS15255 15ca16bbd5a65e7696dbc0552fbdab6e 1444 SMART SM00028 652 685 0.36 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS15255 15ca16bbd5a65e7696dbc0552fbdab6e 1444 SMART SM00028 856 889 18.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS15255 15ca16bbd5a65e7696dbc0552fbdab6e 1444 SUPERFAMILY SSF48452 952 1094 3.45E-12 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS15255 15ca16bbd5a65e7696dbc0552fbdab6e 1444 SUPERFAMILY SSF48452 1277 1328 3.45E-12 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS15255 15ca16bbd5a65e7696dbc0552fbdab6e 1444 SUPERFAMILY SSF48439 532 712 1.91E-17 T 11-11-2016 AUP74_RS15255 15ca16bbd5a65e7696dbc0552fbdab6e 1444 Pfam PF13432 Tetratricopeptide repeat 828 887 6.9E-6 T 11-11-2016 AUP74_RS15255 15ca16bbd5a65e7696dbc0552fbdab6e 1444 Pfam PF13432 Tetratricopeptide repeat 764 819 0.01 T 11-11-2016 AUP74_RS15255 15ca16bbd5a65e7696dbc0552fbdab6e 1444 SUPERFAMILY SSF81901 288 510 3.66E-8 T 11-11-2016 AUP74_RS15255 15ca16bbd5a65e7696dbc0552fbdab6e 1444 Pfam PF13181 Tetratricopeptide repeat 652 682 0.023 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS15255 15ca16bbd5a65e7696dbc0552fbdab6e 1444 Gene3D G3DSA:1.25.40.10 735 925 1.5E-30 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS15255 15ca16bbd5a65e7696dbc0552fbdab6e 1444 Pfam PF13529 Peptidase_C39 like family 92 199 1.0E-12 T 11-11-2016 AUP74_RS15255 15ca16bbd5a65e7696dbc0552fbdab6e 1444 SUPERFAMILY SSF48452 751 893 9.49E-27 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS15255 15ca16bbd5a65e7696dbc0552fbdab6e 1444 SUPERFAMILY SSF48452 938 979 9.49E-27 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS15255 15ca16bbd5a65e7696dbc0552fbdab6e 1444 Gene3D G3DSA:1.25.40.10 253 509 3.9E-13 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS15255 15ca16bbd5a65e7696dbc0552fbdab6e 1444 Gene3D G3DSA:1.25.40.10 525 703 1.1E-24 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS15255 15ca16bbd5a65e7696dbc0552fbdab6e 1444 Gene3D G3DSA:1.25.40.10 939 1089 2.3E-14 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS15255 15ca16bbd5a65e7696dbc0552fbdab6e 1444 Gene3D G3DSA:1.25.40.10 1259 1327 2.3E-14 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS03055 1742f715f0c2f97fb7275289da81661f 853 SUPERFAMILY SSF55486 88 116 1.0E-10 T 11-11-2016 AUP74_RS03055 1742f715f0c2f97fb7275289da81661f 853 SUPERFAMILY SSF55486 287 325 1.0E-10 T 11-11-2016 AUP74_RS03055 1742f715f0c2f97fb7275289da81661f 853 SUPERFAMILY SSF55486 157 240 1.0E-10 T 11-11-2016 AUP74_RS03055 1742f715f0c2f97fb7275289da81661f 853 Gene3D G3DSA:3.40.390.10 287 326 3.9E-12 T 11-11-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 AUP74_RS03055 1742f715f0c2f97fb7275289da81661f 853 Gene3D G3DSA:3.40.390.10 93 172 3.9E-12 T 11-11-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 AUP74_RS03055 1742f715f0c2f97fb7275289da81661f 853 Gene3D G3DSA:3.40.390.10 215 243 3.9E-12 T 11-11-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 AUP74_RS03055 1742f715f0c2f97fb7275289da81661f 853 Pfam PF00413 Matrixin 91 251 1.0E-6 T 11-11-2016 IPR001818 Peptidase M10, metallopeptidase GO:0004222|GO:0006508|GO:0008270|GO:0031012 AUP74_RS02055 fa1dfe6e35a8f3b08a00d1fd3554eedd 556 PRINTS PR00110 Alpha-amylase signature 150 161 4.3E-5 T 11-11-2016 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 AUP74_RS02055 fa1dfe6e35a8f3b08a00d1fd3554eedd 556 PRINTS PR00110 Alpha-amylase signature 264 275 4.3E-5 T 11-11-2016 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 AUP74_RS02055 fa1dfe6e35a8f3b08a00d1fd3554eedd 556 Pfam PF00128 Alpha amylase, catalytic domain 73 423 4.5E-44 T 11-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AUP74_RS02055 fa1dfe6e35a8f3b08a00d1fd3554eedd 556 Gene3D G3DSA:3.20.20.80 34 206 1.0E-78 T 11-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 AUP74_RS02055 fa1dfe6e35a8f3b08a00d1fd3554eedd 556 Gene3D G3DSA:3.20.20.80 244 472 1.0E-78 T 11-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 AUP74_RS02055 fa1dfe6e35a8f3b08a00d1fd3554eedd 556 SUPERFAMILY SSF51445 245 473 8.45E-74 T 11-11-2016 IPR017853 Glycoside hydrolase superfamily AUP74_RS02055 fa1dfe6e35a8f3b08a00d1fd3554eedd 556 SUPERFAMILY SSF51445 30 207 8.45E-74 T 11-11-2016 IPR017853 Glycoside hydrolase superfamily AUP74_RS02055 fa1dfe6e35a8f3b08a00d1fd3554eedd 556 SMART SM00642 41 466 4.6E-70 T 11-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AUP74_RS14060 62ecf0212558c9ac6f56fdc128a5843a 617 Gene3D G3DSA:3.20.20.300 30 384 1.3E-97 T 11-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AUP74_RS14060 62ecf0212558c9ac6f56fdc128a5843a 617 SUPERFAMILY SSF51445 16 419 5.79E-83 T 11-11-2016 IPR017853 Glycoside hydrolase superfamily AUP74_RS14060 62ecf0212558c9ac6f56fdc128a5843a 617 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 292 309 - T 11-11-2016 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 AUP74_RS14060 62ecf0212558c9ac6f56fdc128a5843a 617 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 16 379 1.7E-86 T 11-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AUP74_RS04565 41b8696dd1c6d5a3c55ab03fa0c99c3d 320 Gene3D G3DSA:3.10.25.10 210 318 3.9E-33 T 11-11-2016 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AUP74_RS04565 41b8696dd1c6d5a3c55ab03fa0c99c3d 320 Pfam PF02911 Formyl transferase, C-terminal domain 207 308 1.6E-29 T 11-11-2016 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AUP74_RS04565 41b8696dd1c6d5a3c55ab03fa0c99c3d 320 SUPERFAMILY SSF53328 3 207 4.19E-67 T 11-11-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AUP74_RS04565 41b8696dd1c6d5a3c55ab03fa0c99c3d 320 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 5 309 4.0E-96 T 11-11-2016 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 AUP74_RS04565 41b8696dd1c6d5a3c55ab03fa0c99c3d 320 Pfam PF00551 Formyl transferase 6 184 4.4E-46 T 11-11-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AUP74_RS04565 41b8696dd1c6d5a3c55ab03fa0c99c3d 320 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 5 311 38.213 T 11-11-2016 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 AUP74_RS04565 41b8696dd1c6d5a3c55ab03fa0c99c3d 320 Gene3D G3DSA:3.40.50.170 4 209 2.4E-75 T 11-11-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AUP74_RS04565 41b8696dd1c6d5a3c55ab03fa0c99c3d 320 SUPERFAMILY SSF50486 208 312 7.69E-32 T 11-11-2016 IPR011034 Formyl transferase, C-terminal-like GO:0003824 AUP74_RS03525 2081f0b5de46a07cd1c5550026c3a923 515 SUPERFAMILY SSF68923 6 201 5.41E-71 T 11-11-2016 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 AUP74_RS03525 2081f0b5de46a07cd1c5550026c3a923 515 ProSitePatterns PS00532 Phosphoenolpyruvate carboxykinase (ATP) signature. 239 254 - T 11-11-2016 IPR015994 Phosphoenolpyruvate carboxykinase (ATP), conserved site GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 AUP74_RS03525 2081f0b5de46a07cd1c5550026c3a923 515 Gene3D G3DSA:3.90.228.20 202 264 8.5E-108 T 11-11-2016 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 AUP74_RS03525 2081f0b5de46a07cd1c5550026c3a923 515 Gene3D G3DSA:3.90.228.20 324 513 8.5E-108 T 11-11-2016 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 AUP74_RS03525 2081f0b5de46a07cd1c5550026c3a923 515 Hamap MF_00453 Phosphoenolpyruvate carboxykinase [ATP] [pckA]. 3 515 51.294 T 11-11-2016 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 AUP74_RS03525 2081f0b5de46a07cd1c5550026c3a923 515 TIGRFAM TIGR00224 pckA: phosphoenolpyruvate carboxykinase (ATP) 4 514 1.9E-189 T 11-11-2016 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 AUP74_RS03525 2081f0b5de46a07cd1c5550026c3a923 515 SUPERFAMILY SSF53795 202 514 1.19E-126 T 11-11-2016 AUP74_RS03525 2081f0b5de46a07cd1c5550026c3a923 515 Gene3D G3DSA:3.40.449.10 10 200 1.3E-68 T 11-11-2016 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 AUP74_RS03525 2081f0b5de46a07cd1c5550026c3a923 515 PIRSF PIRSF006294 1 515 4.3E-212 T 11-11-2016 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 AUP74_RS03525 2081f0b5de46a07cd1c5550026c3a923 515 Pfam PF01293 Phosphoenolpyruvate carboxykinase 10 469 4.2E-194 T 11-11-2016 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 AUP74_RS14775 785046e42f424d2a35907caaed9d836f 212 SMART SM00934 1 206 2.8E-81 T 11-11-2016 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 AUP74_RS14775 785046e42f424d2a35907caaed9d836f 212 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 37 50 - T 11-11-2016 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 AUP74_RS14775 785046e42f424d2a35907caaed9d836f 212 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 1 211 34.969 T 11-11-2016 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 AUP74_RS14775 785046e42f424d2a35907caaed9d836f 212 Gene3D G3DSA:3.20.20.70 1 210 8.1E-83 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS14775 785046e42f424d2a35907caaed9d836f 212 SUPERFAMILY SSF51366 1 210 6.77E-71 T 11-11-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 AUP74_RS14775 785046e42f424d2a35907caaed9d836f 212 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 1 206 4.2E-47 T 11-11-2016 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 AUP74_RS14775 785046e42f424d2a35907caaed9d836f 212 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 2 206 6.3E-54 T 11-11-2016 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 AUP74_RS01465 76dad57f9f06b9bcf5426759ae819dd1 283 Gene3D G3DSA:3.30.1380.10 24 282 1.5E-89 T 11-11-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 AUP74_RS01465 76dad57f9f06b9bcf5426759ae819dd1 283 PIRSF PIRSF018455 1 283 7.5E-95 T 11-11-2016 IPR005073 Peptidase M74, penicillin-insensitive murein endopeptidase GO:0004252|GO:0006508|GO:0030288 AUP74_RS01465 76dad57f9f06b9bcf5426759ae819dd1 283 Pfam PF03411 Penicillin-insensitive murein endopeptidase 39 280 5.0E-90 T 11-11-2016 IPR005073 Peptidase M74, penicillin-insensitive murein endopeptidase GO:0004252|GO:0006508|GO:0030288 AUP74_RS01465 76dad57f9f06b9bcf5426759ae819dd1 283 SUPERFAMILY SSF55166 24 280 4.39E-84 T 11-11-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 AUP74_RS03500 a62fe8b70b5c7b6570f7d35694b11cea 220 Pfam PF13419 Haloacid dehalogenase-like hydrolase 10 185 1.3E-11 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS03500 a62fe8b70b5c7b6570f7d35694b11cea 220 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 81 184 2.6E-9 T 11-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 AUP74_RS03500 a62fe8b70b5c7b6570f7d35694b11cea 220 SUPERFAMILY SSF56784 2 214 6.72E-39 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS03500 a62fe8b70b5c7b6570f7d35694b11cea 220 Gene3D G3DSA:3.40.50.1000 8 191 1.2E-25 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS02490 fae7cecb2d69d972eceadd8221b1eff9 124 Pfam PF13767 Domain of unknown function (DUF4168) 37 113 1.5E-14 T 11-11-2016 IPR025433 Domain of unknown function DUF4168 AUP74_RS03455 7eb60db87e92c53431b98fdd8c1a89b3 190 Pfam PF11159 Protein of unknown function (DUF2939) 11 102 1.2E-16 T 11-11-2016 IPR021330 Protein of unknown function DUF2939 AUP74_RS03400 b32ab2151df11fa3e4e730fb27b82c36 535 Pfam PF02225 PA domain 340 430 3.0E-6 T 11-11-2016 IPR003137 PA domain AUP74_RS03400 b32ab2151df11fa3e4e730fb27b82c36 535 PRINTS PR00723 Subtilisin serine protease family (S8) signature 453 469 2.1E-16 T 11-11-2016 IPR015500 Peptidase S8, subtilisin-related AUP74_RS03400 b32ab2151df11fa3e4e730fb27b82c36 535 PRINTS PR00723 Subtilisin serine protease family (S8) signature 116 135 2.1E-16 T 11-11-2016 IPR015500 Peptidase S8, subtilisin-related AUP74_RS03400 b32ab2151df11fa3e4e730fb27b82c36 535 PRINTS PR00723 Subtilisin serine protease family (S8) signature 154 167 2.1E-16 T 11-11-2016 IPR015500 Peptidase S8, subtilisin-related AUP74_RS03400 b32ab2151df11fa3e4e730fb27b82c36 535 Pfam PF00082 Subtilase family 118 308 1.6E-27 T 11-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AUP74_RS03400 b32ab2151df11fa3e4e730fb27b82c36 535 Pfam PF00082 Subtilase family 449 504 1.1E-12 T 11-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AUP74_RS03400 b32ab2151df11fa3e4e730fb27b82c36 535 Gene3D G3DSA:3.50.30.30 298 443 1.4E-20 T 11-11-2016 AUP74_RS03400 b32ab2151df11fa3e4e730fb27b82c36 535 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 158 168 - T 11-11-2016 IPR022398 Peptidase S8, subtilisin, His-active site AUP74_RS03400 b32ab2151df11fa3e4e730fb27b82c36 535 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 454 464 - T 11-11-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site AUP74_RS03400 b32ab2151df11fa3e4e730fb27b82c36 535 Gene3D G3DSA:3.40.50.200 116 297 1.9E-72 T 11-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AUP74_RS03400 b32ab2151df11fa3e4e730fb27b82c36 535 Gene3D G3DSA:3.40.50.200 448 516 1.9E-72 T 11-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AUP74_RS03400 b32ab2151df11fa3e4e730fb27b82c36 535 SUPERFAMILY SSF52743 101 515 2.61E-75 T 11-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AUP74_RS06165 170b03bed8e8b4aac5a656aeceed5cc6 404 Gene3D G3DSA:3.90.1150.10 278 385 1.7E-32 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS06165 170b03bed8e8b4aac5a656aeceed5cc6 404 Gene3D G3DSA:3.40.640.10 60 277 1.5E-81 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AUP74_RS06165 170b03bed8e8b4aac5a656aeceed5cc6 404 SUPERFAMILY SSF53383 4 389 1.21E-103 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase AUP74_RS06165 170b03bed8e8b4aac5a656aeceed5cc6 404 Hamap MF_01693 8-amino-7-oxononanoate synthase [bioF]. 3 389 45.548 T 11-11-2016 IPR022834 8-amino-7-oxononanoate synthase, Proteobacteria GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 AUP74_RS06165 170b03bed8e8b4aac5a656aeceed5cc6 404 Pfam PF00155 Aminotransferase class I and II 40 385 2.8E-59 T 11-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AUP74_RS06165 170b03bed8e8b4aac5a656aeceed5cc6 404 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 19 385 3.6E-139 T 11-11-2016 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 AUP74_RS04325 824ca2f41c34e58158383e56694101f4 248 SUPERFAMILY SSF53639 14 225 1.94E-66 T 11-11-2016 IPR001303 Class II aldolase/adducin N-terminal AUP74_RS04325 824ca2f41c34e58158383e56694101f4 248 SMART SM01007 19 199 1.9E-54 T 11-11-2016 IPR001303 Class II aldolase/adducin N-terminal AUP74_RS04325 824ca2f41c34e58158383e56694101f4 248 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 20 199 3.5E-49 T 11-11-2016 IPR001303 Class II aldolase/adducin N-terminal AUP74_RS04325 824ca2f41c34e58158383e56694101f4 248 Gene3D G3DSA:3.40.225.10 14 215 6.5E-65 T 11-11-2016 IPR001303 Class II aldolase/adducin N-terminal AUP74_RS06720 c73c2a49561ba089e1b88ee34ac9cedd 234 Gene3D G3DSA:3.30.70.1070 89 148 7.3E-4 T 11-11-2016 IPR007730 Sporulation-related domain GO:0042834 AUP74_RS06720 c73c2a49561ba089e1b88ee34ac9cedd 234 SUPERFAMILY SSF110997 83 149 1.7E-6 T 11-11-2016 IPR007730 Sporulation-related domain GO:0042834 AUP74_RS05835 be3b6e750861a2b80a04d4a040afcba5 437 Pfam PF13167 GTP-binding GTPase N-terminal 29 113 6.5E-30 T 11-11-2016 IPR025121 GTPase HflX, N-terminal AUP74_RS05835 be3b6e750861a2b80a04d4a040afcba5 437 SUPERFAMILY SSF52540 199 366 9.38E-42 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05835 be3b6e750861a2b80a04d4a040afcba5 437 Gene3D G3DSA:3.40.50.300 199 363 5.2E-33 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05835 be3b6e750861a2b80a04d4a040afcba5 437 Pfam PF16360 GTP-binding GTPase Middle Region 115 193 1.2E-29 T 11-11-2016 IPR032305 GTP-binding protein, middle domain AUP74_RS05835 be3b6e750861a2b80a04d4a040afcba5 437 PIRSF PIRSF006809 4 422 1.9E-145 T 11-11-2016 IPR016496 GTPase HflX GO:0005525 AUP74_RS05835 be3b6e750861a2b80a04d4a040afcba5 437 Hamap MF_00900 GTPase HflX [hflX]. 28 391 46.638 T 11-11-2016 IPR016496 GTPase HflX GO:0005525 AUP74_RS05835 be3b6e750861a2b80a04d4a040afcba5 437 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 201 221 2.1E-8 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 AUP74_RS05835 be3b6e750861a2b80a04d4a040afcba5 437 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 222 240 2.1E-8 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 AUP74_RS05835 be3b6e750861a2b80a04d4a040afcba5 437 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 268 286 2.1E-8 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 AUP74_RS05835 be3b6e750861a2b80a04d4a040afcba5 437 Pfam PF01926 50S ribosome-binding GTPase 201 319 7.6E-20 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 AUP74_RS05835 be3b6e750861a2b80a04d4a040afcba5 437 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 12 362 6.3E-152 T 11-11-2016 IPR016496 GTPase HflX GO:0005525 AUP74_RS05835 be3b6e750861a2b80a04d4a040afcba5 437 SUPERFAMILY SSF54980 366 418 7.19E-7 T 11-11-2016 IPR009022 Elongation factor G, III-V domain AUP74_RS01430 b3e1a6c3c792847eda1125853fccfb24 868 Gene3D G3DSA:1.10.510.10 78 269 4.4E-50 T 11-11-2016 AUP74_RS01430 b3e1a6c3c792847eda1125853fccfb24 868 SMART SM00028 587 620 0.01 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS01430 b3e1a6c3c792847eda1125853fccfb24 868 SMART SM00028 687 720 130.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS01430 b3e1a6c3c792847eda1125853fccfb24 868 SMART SM00028 721 754 56.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS01430 b3e1a6c3c792847eda1125853fccfb24 868 Pfam PF00069 Protein kinase domain 14 266 2.5E-54 T 11-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AUP74_RS01430 b3e1a6c3c792847eda1125853fccfb24 868 SUPERFAMILY SSF48452 563 676 1.12E-12 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS01430 b3e1a6c3c792847eda1125853fccfb24 868 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 130 142 - T 11-11-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AUP74_RS01430 b3e1a6c3c792847eda1125853fccfb24 868 Gene3D G3DSA:1.25.40.10 576 674 9.0E-13 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS01430 b3e1a6c3c792847eda1125853fccfb24 868 SUPERFAMILY SSF48452 688 821 2.28E-13 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS01430 b3e1a6c3c792847eda1125853fccfb24 868 Gene3D G3DSA:3.30.200.20 7 77 2.3E-25 T 11-11-2016 AUP74_RS01430 b3e1a6c3c792847eda1125853fccfb24 868 SUPERFAMILY SSF56112 5 265 1.16E-74 T 11-11-2016 IPR011009 Protein kinase-like domain AUP74_RS01430 b3e1a6c3c792847eda1125853fccfb24 868 Gene3D G3DSA:1.25.40.10 690 820 1.1E-12 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS01430 b3e1a6c3c792847eda1125853fccfb24 868 SMART SM00220 13 277 2.6E-61 T 11-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AUP74_RS01430 b3e1a6c3c792847eda1125853fccfb24 868 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 19 42 - T 11-11-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 AUP74_RS07610 99670cdbd494565a03bdec83a9344e12 360 Gene3D G3DSA:3.40.50.410 163 294 1.8E-5 T 11-11-2016 IPR002035 von Willebrand factor, type A AUP74_RS07610 99670cdbd494565a03bdec83a9344e12 360 Pfam PF13519 von Willebrand factor type A domain 163 288 3.6E-7 T 11-11-2016 IPR002035 von Willebrand factor, type A AUP74_RS07610 99670cdbd494565a03bdec83a9344e12 360 SUPERFAMILY SSF53300 163 355 1.2E-13 T 11-11-2016 IPR002035 von Willebrand factor, type A AUP74_RS15015 355f8af43750eda23c45d89fa5e84d6d 443 Gene3D G3DSA:2.30.40.10 383 410 3.2E-8 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS15015 355f8af43750eda23c45d89fa5e84d6d 443 Pfam PF01979 Amidohydrolase family 85 435 3.8E-53 T 11-11-2016 IPR006680 Amidohydrolase-related GO:0016787 AUP74_RS15015 355f8af43750eda23c45d89fa5e84d6d 443 SUPERFAMILY SSF51556 89 399 9.95E-113 T 11-11-2016 IPR032466 Metal-dependent hydrolase AUP74_RS15015 355f8af43750eda23c45d89fa5e84d6d 443 Gene3D G3DSA:2.30.40.10 33 90 4.5E-26 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS15015 355f8af43750eda23c45d89fa5e84d6d 443 Gene3D G3DSA:2.30.40.10 411 439 4.5E-26 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS15015 355f8af43750eda23c45d89fa5e84d6d 443 SUPERFAMILY SSF51338 35 89 2.97E-10 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS15015 355f8af43750eda23c45d89fa5e84d6d 443 SUPERFAMILY SSF51338 399 437 2.97E-10 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS15015 355f8af43750eda23c45d89fa5e84d6d 443 Gene3D G3DSA:3.20.20.140 91 382 1.3E-93 T 11-11-2016 AUP74_RS02025 0a9022b4285e601d031b930b1d2bd75a 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.8E-13 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS02025 0a9022b4285e601d031b930b1d2bd75a 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.8E-13 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS02025 0a9022b4285e601d031b930b1d2bd75a 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 2.8E-13 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS02025 0a9022b4285e601d031b930b1d2bd75a 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 3.5E-26 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS02025 0a9022b4285e601d031b930b1d2bd75a 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 3.5E-26 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS02025 0a9022b4285e601d031b930b1d2bd75a 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 3.5E-26 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS02025 0a9022b4285e601d031b930b1d2bd75a 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 3.5E-26 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS02025 0a9022b4285e601d031b930b1d2bd75a 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.5E-26 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS02025 0a9022b4285e601d031b930b1d2bd75a 274 SUPERFAMILY SSF51735 4 262 4.03E-59 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS02025 0a9022b4285e601d031b930b1d2bd75a 274 Gene3D G3DSA:3.40.50.720 7 231 2.1E-56 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS02025 0a9022b4285e601d031b930b1d2bd75a 274 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 197 0.0011 T 11-11-2016 AUP74_RS02025 0a9022b4285e601d031b930b1d2bd75a 274 Pfam PF00106 short chain dehydrogenase 9 196 3.9E-43 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS02025 0a9022b4285e601d031b930b1d2bd75a 274 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 11-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AUP74_RS02820 673eb9364fa1b3364cb874d457cbd734 843 SUPERFAMILY SSF56601 516 819 2.88E-22 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS02820 673eb9364fa1b3364cb874d457cbd734 843 Pfam PF15780 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin 177 258 4.3E-9 T 11-11-2016 IPR031549 Abnormal spindle-like microcephaly-associated protein, ASH domain AUP74_RS02820 673eb9364fa1b3364cb874d457cbd734 843 Gene3D G3DSA:3.40.710.10 542 815 4.6E-14 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS02820 673eb9364fa1b3364cb874d457cbd734 843 Gene3D G3DSA:2.60.40.360 172 270 7.5E-15 T 11-11-2016 IPR008962 PapD-like AUP74_RS15720 be4bbbd8128aa8d05789300db76cf920 458 SMART SM00388 233 297 6.6E-7 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS15720 be4bbbd8128aa8d05789300db76cf920 458 Pfam PF00512 His Kinase A (phospho-acceptor) domain 234 291 5.1E-8 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS15720 be4bbbd8128aa8d05789300db76cf920 458 Gene3D G3DSA:1.10.287.130 223 291 2.8E-11 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS15720 be4bbbd8128aa8d05789300db76cf920 458 Pfam PF00672 HAMP domain 160 228 1.3E-16 T 11-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 AUP74_RS15720 be4bbbd8128aa8d05789300db76cf920 458 SUPERFAMILY SSF158472 177 230 5.62E-9 T 11-11-2016 AUP74_RS15720 be4bbbd8128aa8d05789300db76cf920 458 SUPERFAMILY SSF55874 303 454 7.33E-36 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS15720 be4bbbd8128aa8d05789300db76cf920 458 SMART SM00304 177 232 6.1E-12 T 11-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 AUP74_RS15720 be4bbbd8128aa8d05789300db76cf920 458 Gene3D G3DSA:3.30.565.10 304 452 1.1E-35 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS15720 be4bbbd8128aa8d05789300db76cf920 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 407 5.2E-12 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS15720 be4bbbd8128aa8d05789300db76cf920 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 393 5.2E-12 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS15720 be4bbbd8128aa8d05789300db76cf920 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 432 5.2E-12 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS15720 be4bbbd8128aa8d05789300db76cf920 458 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 346 452 6.1E-17 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS15720 be4bbbd8128aa8d05789300db76cf920 458 SUPERFAMILY SSF47384 216 291 4.12E-11 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS15720 be4bbbd8128aa8d05789300db76cf920 458 SMART SM00387 342 454 5.2E-30 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS15470 7e5414c5835f0839e171bb05cb4e6793 209 Pfam PF04011 LemA family 22 208 2.3E-65 T 11-11-2016 IPR007156 LemA AUP74_RS15470 7e5414c5835f0839e171bb05cb4e6793 209 SUPERFAMILY SSF140478 38 183 1.31E-52 T 11-11-2016 IPR023353 LemA-like domain AUP74_RS15470 7e5414c5835f0839e171bb05cb4e6793 209 Gene3D G3DSA:1.20.1440.20 29 208 6.1E-62 T 11-11-2016 IPR023353 LemA-like domain AUP74_RS10100 f4aba40451039c194dda3d6584903ca6 213 SUPERFAMILY SSF53335 12 211 1.41E-40 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS10100 f4aba40451039c194dda3d6584903ca6 213 Gene3D G3DSA:3.40.50.150 14 210 2.8E-52 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS10100 f4aba40451039c194dda3d6584903ca6 213 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 2 213 36.187 T 11-11-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 AUP74_RS10100 f4aba40451039c194dda3d6584903ca6 213 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 7 209 1.2E-55 T 11-11-2016 AUP74_RS10100 f4aba40451039c194dda3d6584903ca6 213 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 2 211 1.1E-59 T 11-11-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 AUP74_RS09185 1ffbe47ed722561693ab15f369ea24bd 487 SUPERFAMILY SSF53720 6 483 1.26E-168 T 11-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AUP74_RS09185 1ffbe47ed722561693ab15f369ea24bd 487 Pfam PF00171 Aldehyde dehydrogenase family 20 479 5.0E-167 T 11-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 AUP74_RS09185 1ffbe47ed722561693ab15f369ea24bd 487 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 284 295 - T 11-11-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 AUP74_RS09185 1ffbe47ed722561693ab15f369ea24bd 487 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 256 263 - T 11-11-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 AUP74_RS09185 1ffbe47ed722561693ab15f369ea24bd 487 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 31 478 1.5E-212 T 11-11-2016 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 AUP74_RS09185 1ffbe47ed722561693ab15f369ea24bd 487 Gene3D G3DSA:3.40.309.10 270 455 1.7E-69 T 11-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 AUP74_RS09185 1ffbe47ed722561693ab15f369ea24bd 487 Gene3D G3DSA:3.40.605.10 10 269 1.3E-97 T 11-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AUP74_RS10545 1dabb891ecfa5e37bac5443148db7e5f 374 Pfam PF11890 Domain of unknown function (DUF3410) 302 362 4.0E-11 T 11-11-2016 IPR024531 Erythronate-4-phosphate dehydrogenase, dimerisation domain GO:0046983 KEGG: 00260+1.1.1.29|KEGG: 00630+1.1.1.29|KEGG: 00680+1.1.1.29|KEGG: 00750+1.1.1.290|MetaCyc: PWY-181 AUP74_RS10545 1dabb891ecfa5e37bac5443148db7e5f 374 Gene3D G3DSA:3.40.50.720 2 107 3.7E-18 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS10545 1dabb891ecfa5e37bac5443148db7e5f 374 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 105 248 3.2E-28 T 11-11-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 AUP74_RS10545 1dabb891ecfa5e37bac5443148db7e5f 374 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 32 265 2.0E-14 T 11-11-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 AUP74_RS10545 1dabb891ecfa5e37bac5443148db7e5f 374 SUPERFAMILY SSF51735 91 249 2.07E-31 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS10545 1dabb891ecfa5e37bac5443148db7e5f 374 Hamap MF_01825 Erythronate-4-phosphate dehydrogenase [pdxB]. 1 356 41.011 T 11-11-2016 IPR020921 Erythronate-4-phosphate dehydrogenase GO:0005737|GO:0008615|GO:0033711|GO:0055114 KEGG: 00260+1.1.1.29|KEGG: 00630+1.1.1.29|KEGG: 00680+1.1.1.29|KEGG: 00750+1.1.1.290|MetaCyc: PWY-181 AUP74_RS10545 1dabb891ecfa5e37bac5443148db7e5f 374 SUPERFAMILY SSF52283 4 108 1.06E-16 T 11-11-2016 AUP74_RS10545 1dabb891ecfa5e37bac5443148db7e5f 374 Gene3D G3DSA:3.40.50.720 108 251 2.2E-32 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS12290 8d0a3efd1881804ef61f4b3cdd385d99 913 Pfam PF00593 TonB dependent receptor 646 912 1.7E-19 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS12290 8d0a3efd1881804ef61f4b3cdd385d99 913 Gene3D G3DSA:2.170.130.10 75 172 1.7E-6 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS12290 8d0a3efd1881804ef61f4b3cdd385d99 913 Pfam PF07715 TonB-dependent Receptor Plug Domain 76 161 4.2E-5 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS12290 8d0a3efd1881804ef61f4b3cdd385d99 913 Gene3D G3DSA:2.40.170.20 484 913 3.1E-40 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS12290 8d0a3efd1881804ef61f4b3cdd385d99 913 Gene3D G3DSA:2.40.170.20 173 231 3.1E-40 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS12290 8d0a3efd1881804ef61f4b3cdd385d99 913 Gene3D G3DSA:2.40.170.20 263 392 3.1E-40 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS12290 8d0a3efd1881804ef61f4b3cdd385d99 913 SUPERFAMILY SSF56935 642 913 4.58E-64 T 11-11-2016 AUP74_RS12290 8d0a3efd1881804ef61f4b3cdd385d99 913 SUPERFAMILY SSF56935 50 193 4.58E-64 T 11-11-2016 AUP74_RS12290 8d0a3efd1881804ef61f4b3cdd385d99 913 SUPERFAMILY SSF56935 279 612 4.58E-64 T 11-11-2016 AUP74_RS04585 fa0a691ae46828391bbc020eb7ed2e08 171 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 6 161 3.9E-54 T 11-11-2016 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AUP74_RS04585 fa0a691ae46828391bbc020eb7ed2e08 171 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 6 158 29.11 T 11-11-2016 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AUP74_RS04585 fa0a691ae46828391bbc020eb7ed2e08 171 Pfam PF00731 AIR carboxylase 6 151 1.2E-53 T 11-11-2016 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AUP74_RS04585 fa0a691ae46828391bbc020eb7ed2e08 171 SUPERFAMILY SSF52255 4 166 1.57E-54 T 11-11-2016 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AUP74_RS04585 fa0a691ae46828391bbc020eb7ed2e08 171 Gene3D G3DSA:3.40.50.7700 2 163 1.0E-60 T 11-11-2016 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AUP74_RS04585 fa0a691ae46828391bbc020eb7ed2e08 171 PIRSF PIRSF001338 1 165 3.4E-58 T 11-11-2016 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 AUP74_RS04585 fa0a691ae46828391bbc020eb7ed2e08 171 SMART SM01001 4 154 4.9E-76 T 11-11-2016 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AUP74_RS02395 9c7994ef5299b5084dac90d074c766e0 752 SMART SM00065 17 164 9.1E-25 T 11-11-2016 IPR003018 GAF domain GO:0005515 AUP74_RS02395 9c7994ef5299b5084dac90d074c766e0 752 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 618 636 - T 11-11-2016 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 AUP74_RS02395 9c7994ef5299b5084dac90d074c766e0 752 Gene3D G3DSA:3.20.20.60 428 741 1.3E-105 T 11-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AUP74_RS02395 9c7994ef5299b5084dac90d074c766e0 752 SUPERFAMILY SSF52009 298 418 1.7E-27 T 11-11-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 AUP74_RS02395 9c7994ef5299b5084dac90d074c766e0 752 Gene3D G3DSA:3.50.30.10 307 427 3.7E-29 T 11-11-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 AUP74_RS02395 9c7994ef5299b5084dac90d074c766e0 752 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 177 733 1.4E-140 T 11-11-2016 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 AUP74_RS02395 9c7994ef5299b5084dac90d074c766e0 752 Gene3D G3DSA:3.30.450.40 3 163 3.4E-48 T 11-11-2016 IPR029016 GAF domain-like AUP74_RS02395 9c7994ef5299b5084dac90d074c766e0 752 Pfam PF00391 PEP-utilising enzyme, mobile domain 325 397 3.7E-16 T 11-11-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 AUP74_RS02395 9c7994ef5299b5084dac90d074c766e0 752 Gene3D G3DSA:1.10.274.10 207 306 7.2E-32 T 11-11-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 AUP74_RS02395 9c7994ef5299b5084dac90d074c766e0 752 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 671 683 1.1E-23 T 11-11-2016 AUP74_RS02395 9c7994ef5299b5084dac90d074c766e0 752 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 635 650 1.1E-23 T 11-11-2016 AUP74_RS02395 9c7994ef5299b5084dac90d074c766e0 752 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 618 633 1.1E-23 T 11-11-2016 AUP74_RS02395 9c7994ef5299b5084dac90d074c766e0 752 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 465 484 1.1E-23 T 11-11-2016 AUP74_RS02395 9c7994ef5299b5084dac90d074c766e0 752 SUPERFAMILY SSF47831 206 314 5.49E-29 T 11-11-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 AUP74_RS02395 9c7994ef5299b5084dac90d074c766e0 752 SUPERFAMILY SSF51621 426 710 1.94E-103 T 11-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AUP74_RS02395 9c7994ef5299b5084dac90d074c766e0 752 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 429 711 8.0E-99 T 11-11-2016 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 AUP74_RS02395 9c7994ef5299b5084dac90d074c766e0 752 SUPERFAMILY SSF55781 2 158 4.58E-31 T 11-11-2016 IPR029016 GAF domain-like AUP74_RS02395 9c7994ef5299b5084dac90d074c766e0 752 Pfam PF05524 PEP-utilising enzyme, N-terminal 177 299 4.4E-27 T 11-11-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 AUP74_RS02395 9c7994ef5299b5084dac90d074c766e0 752 Pfam PF13185 GAF domain 15 154 4.5E-16 T 11-11-2016 IPR003018 GAF domain GO:0005515 AUP74_RS07940 086ff80c24544ce0cad37488e1896d77 215 Gene3D G3DSA:3.90.20.20 59 156 1.9E-29 T 11-11-2016 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 AUP74_RS07940 086ff80c24544ce0cad37488e1896d77 215 ProSitePatterns PS01071 grpE protein signature. 168 211 - T 11-11-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AUP74_RS07940 086ff80c24544ce0cad37488e1896d77 215 Hamap MF_01151 Protein GrpE [grpE]. 7 213 22.876 T 11-11-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AUP74_RS07940 086ff80c24544ce0cad37488e1896d77 215 Pfam PF01025 GrpE 49 213 1.4E-55 T 11-11-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AUP74_RS07940 086ff80c24544ce0cad37488e1896d77 215 SUPERFAMILY SSF51064 158 213 1.29E-20 T 11-11-2016 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 AUP74_RS07940 086ff80c24544ce0cad37488e1896d77 215 Gene3D G3DSA:2.30.22.10 157 214 3.3E-29 T 11-11-2016 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 AUP74_RS07940 086ff80c24544ce0cad37488e1896d77 215 SUPERFAMILY SSF58014 60 157 3.27E-27 T 11-11-2016 AUP74_RS07940 086ff80c24544ce0cad37488e1896d77 215 PRINTS PR00773 GrpE protein signature 82 98 6.6E-30 T 11-11-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AUP74_RS07940 086ff80c24544ce0cad37488e1896d77 215 PRINTS PR00773 GrpE protein signature 110 125 6.6E-30 T 11-11-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AUP74_RS07940 086ff80c24544ce0cad37488e1896d77 215 PRINTS PR00773 GrpE protein signature 192 211 6.6E-30 T 11-11-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AUP74_RS07940 086ff80c24544ce0cad37488e1896d77 215 PRINTS PR00773 GrpE protein signature 165 180 6.6E-30 T 11-11-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AUP74_RS15625 e42e821e9fd0b28d977c4099d752f9f0 394 Pfam PF13288 DXP reductoisomerase C-terminal domain 269 385 1.0E-41 T 11-11-2016 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 AUP74_RS15625 e42e821e9fd0b28d977c4099d752f9f0 394 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 8 387 6.9E-152 T 11-11-2016 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 AUP74_RS15625 e42e821e9fd0b28d977c4099d752f9f0 394 PIRSF PIRSF006205 6 393 1.8E-149 T 11-11-2016 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 AUP74_RS15625 e42e821e9fd0b28d977c4099d752f9f0 394 Gene3D G3DSA:1.10.1740.10 311 391 9.6E-30 T 11-11-2016 AUP74_RS15625 e42e821e9fd0b28d977c4099d752f9f0 394 Gene3D G3DSA:3.40.50.720 4 154 3.4E-55 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS15625 e42e821e9fd0b28d977c4099d752f9f0 394 SUPERFAMILY SSF51735 6 154 8.35E-46 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS15625 e42e821e9fd0b28d977c4099d752f9f0 394 SUPERFAMILY SSF55347 130 272 8.83E-60 T 11-11-2016 AUP74_RS15625 e42e821e9fd0b28d977c4099d752f9f0 394 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 9 136 1.3E-45 T 11-11-2016 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 AUP74_RS15625 e42e821e9fd0b28d977c4099d752f9f0 394 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 150 237 1.3E-36 T 11-11-2016 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 AUP74_RS15625 e42e821e9fd0b28d977c4099d752f9f0 394 SUPERFAMILY SSF69055 300 391 1.44E-31 T 11-11-2016 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 AUP74_RS15625 e42e821e9fd0b28d977c4099d752f9f0 394 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 9 390 46.717 T 11-11-2016 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 AUP74_RS04360 23bcd6af122c90b74ea2cc04b0e074eb 1115 Gene3D G3DSA:2.30.40.10 1033 1076 6.4E-29 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS04360 23bcd6af122c90b74ea2cc04b0e074eb 1115 Gene3D G3DSA:2.30.40.10 679 741 6.4E-29 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS04360 23bcd6af122c90b74ea2cc04b0e074eb 1115 SUPERFAMILY SSF82171 155 583 6.67E-48 T 11-11-2016 AUP74_RS04360 23bcd6af122c90b74ea2cc04b0e074eb 1115 SUPERFAMILY SSF82171 59 196 1.22E-20 T 11-11-2016 AUP74_RS04360 23bcd6af122c90b74ea2cc04b0e074eb 1115 Pfam PF01979 Amidohydrolase family 736 1069 3.8E-17 T 11-11-2016 IPR006680 Amidohydrolase-related GO:0016787 AUP74_RS04360 23bcd6af122c90b74ea2cc04b0e074eb 1115 Pfam PF07676 WD40-like Beta Propeller Repeat 464 492 0.027 T 11-11-2016 IPR011659 WD40-like Beta Propeller AUP74_RS04360 23bcd6af122c90b74ea2cc04b0e074eb 1115 Pfam PF07676 WD40-like Beta Propeller Repeat 101 136 6.4E-11 T 11-11-2016 IPR011659 WD40-like Beta Propeller AUP74_RS04360 23bcd6af122c90b74ea2cc04b0e074eb 1115 Pfam PF07676 WD40-like Beta Propeller Repeat 155 168 0.18 T 11-11-2016 IPR011659 WD40-like Beta Propeller AUP74_RS04360 23bcd6af122c90b74ea2cc04b0e074eb 1115 Pfam PF07676 WD40-like Beta Propeller Repeat 565 582 0.043 T 11-11-2016 IPR011659 WD40-like Beta Propeller AUP74_RS04360 23bcd6af122c90b74ea2cc04b0e074eb 1115 Pfam PF07676 WD40-like Beta Propeller Repeat 209 225 0.0022 T 11-11-2016 IPR011659 WD40-like Beta Propeller AUP74_RS04360 23bcd6af122c90b74ea2cc04b0e074eb 1115 Pfam PF07676 WD40-like Beta Propeller Repeat 262 291 0.012 T 11-11-2016 IPR011659 WD40-like Beta Propeller AUP74_RS04360 23bcd6af122c90b74ea2cc04b0e074eb 1115 SUPERFAMILY SSF51338 680 740 2.77E-17 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS04360 23bcd6af122c90b74ea2cc04b0e074eb 1115 SUPERFAMILY SSF51338 1033 1069 2.77E-17 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS04360 23bcd6af122c90b74ea2cc04b0e074eb 1115 Gene3D G3DSA:2.120.10.30 385 634 3.0E-38 T 11-11-2016 IPR011042 Six-bladed beta-propeller, TolB-like AUP74_RS04360 23bcd6af122c90b74ea2cc04b0e074eb 1115 Gene3D G3DSA:3.20.20.140 742 1031 2.3E-61 T 11-11-2016 AUP74_RS04360 23bcd6af122c90b74ea2cc04b0e074eb 1115 SUPERFAMILY SSF51556 739 1034 3.4E-43 T 11-11-2016 IPR032466 Metal-dependent hydrolase AUP74_RS04360 23bcd6af122c90b74ea2cc04b0e074eb 1115 Gene3D G3DSA:2.120.10.60 63 355 3.0E-60 T 11-11-2016 AUP74_RS01040 bb6bf3fd9f6ba87102664ed2b3485d26 225 Pfam PF00106 short chain dehydrogenase 5 189 2.3E-45 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS01040 bb6bf3fd9f6ba87102664ed2b3485d26 225 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 4.4E-22 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS01040 bb6bf3fd9f6ba87102664ed2b3485d26 225 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 210 4.4E-22 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS01040 bb6bf3fd9f6ba87102664ed2b3485d26 225 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 4.4E-22 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS01040 bb6bf3fd9f6ba87102664ed2b3485d26 225 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 4.4E-22 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS01040 bb6bf3fd9f6ba87102664ed2b3485d26 225 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 4.4E-22 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS01040 bb6bf3fd9f6ba87102664ed2b3485d26 225 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 4.4E-22 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS01040 bb6bf3fd9f6ba87102664ed2b3485d26 225 Gene3D G3DSA:3.40.50.720 4 212 3.5E-59 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS01040 bb6bf3fd9f6ba87102664ed2b3485d26 225 SUPERFAMILY SSF51735 2 212 6.88E-59 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS16930 02a23ae98e6f672c81c5c231ecb0e0b2 323 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 44 313 1.1E-109 T 11-11-2016 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 AUP74_RS16930 02a23ae98e6f672c81c5c231ecb0e0b2 323 Gene3D G3DSA:3.10.580.10 195 320 2.3E-40 T 11-11-2016 AUP74_RS16930 02a23ae98e6f672c81c5c231ecb0e0b2 323 SMART SM00116 274 322 9.3E-5 T 11-11-2016 IPR000644 CBS domain AUP74_RS16930 02a23ae98e6f672c81c5c231ecb0e0b2 323 SMART SM00116 209 257 0.37 T 11-11-2016 IPR000644 CBS domain AUP74_RS16930 02a23ae98e6f672c81c5c231ecb0e0b2 323 Pfam PF01380 SIS domain 40 171 2.4E-33 T 11-11-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 AUP74_RS16930 02a23ae98e6f672c81c5c231ecb0e0b2 323 Pfam PF00571 CBS domain 200 257 2.1E-5 T 11-11-2016 IPR000644 CBS domain AUP74_RS16930 02a23ae98e6f672c81c5c231ecb0e0b2 323 Pfam PF00571 CBS domain 269 320 5.2E-11 T 11-11-2016 IPR000644 CBS domain AUP74_RS16930 02a23ae98e6f672c81c5c231ecb0e0b2 323 PIRSF PIRSF004692 1 323 6.6E-137 T 11-11-2016 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 AUP74_RS16930 02a23ae98e6f672c81c5c231ecb0e0b2 323 Gene3D G3DSA:3.40.50.10490 17 194 5.2E-52 T 11-11-2016 AUP74_RS16930 02a23ae98e6f672c81c5c231ecb0e0b2 323 SUPERFAMILY SSF53697 14 321 2.18E-70 T 11-11-2016 AUP74_RS04140 fd44ab90b403f203b6e3a66ce05cfb22 201 Gene3D G3DSA:3.40.1410.10 17 182 7.5E-50 T 11-11-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain AUP74_RS04140 fd44ab90b403f203b6e3a66ce05cfb22 201 Hamap MF_01632 Chorismate pyruvate-lyase [ubiC]. 10 184 26.847 T 11-11-2016 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148 AUP74_RS04140 fd44ab90b403f203b6e3a66ce05cfb22 201 SUPERFAMILY SSF64288 11 181 3.6E-44 T 11-11-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain AUP74_RS04140 fd44ab90b403f203b6e3a66ce05cfb22 201 Pfam PF04345 Chorismate lyase 22 179 3.0E-30 T 11-11-2016 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148 AUP74_RS09665 4d1f5697c40dd58827f33ec11cb7658f 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 64 242 8.1E-25 T 11-11-2016 AUP74_RS09665 4d1f5697c40dd58827f33ec11cb7658f 250 Gene3D G3DSA:3.40.50.720 4 243 2.9E-38 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS09665 4d1f5697c40dd58827f33ec11cb7658f 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 2.8E-20 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS09665 4d1f5697c40dd58827f33ec11cb7658f 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.8E-20 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS09665 4d1f5697c40dd58827f33ec11cb7658f 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 2.8E-20 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS09665 4d1f5697c40dd58827f33ec11cb7658f 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 2.8E-20 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS09665 4d1f5697c40dd58827f33ec11cb7658f 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 2.8E-20 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS09665 4d1f5697c40dd58827f33ec11cb7658f 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 2.8E-20 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS09665 4d1f5697c40dd58827f33ec11cb7658f 250 SUPERFAMILY SSF51735 3 243 4.79E-40 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS16440 55ba768f829b21a19aba13ad6deb31a1 427 SUPERFAMILY SSF53901 284 427 2.75E-28 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS16440 55ba768f829b21a19aba13ad6deb31a1 427 Gene3D G3DSA:3.40.47.10 9 128 3.0E-49 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS16440 55ba768f829b21a19aba13ad6deb31a1 427 Gene3D G3DSA:3.40.47.10 216 290 3.0E-49 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS16440 55ba768f829b21a19aba13ad6deb31a1 427 PIRSF PIRSF000429 4 427 2.9E-108 T 11-11-2016 IPR002155 Thiolase GO:0008152|GO:0016747 AUP74_RS16440 55ba768f829b21a19aba13ad6deb31a1 427 SUPERFAMILY SSF53901 9 284 3.29E-60 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS16440 55ba768f829b21a19aba13ad6deb31a1 427 Pfam PF02803 Thiolase, C-terminal domain 286 427 4.5E-31 T 11-11-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 AUP74_RS16440 55ba768f829b21a19aba13ad6deb31a1 427 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 11 426 3.9E-118 T 11-11-2016 IPR002155 Thiolase GO:0008152|GO:0016747 AUP74_RS16440 55ba768f829b21a19aba13ad6deb31a1 427 Pfam PF00108 Thiolase, N-terminal domain 9 277 7.7E-56 T 11-11-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 AUP74_RS16440 55ba768f829b21a19aba13ad6deb31a1 427 Gene3D G3DSA:3.40.47.10 295 426 2.2E-43 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS16440 55ba768f829b21a19aba13ad6deb31a1 427 Gene3D G3DSA:3.40.47.10 172 215 2.2E-43 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS04800 f8a06181cb5f52afddcc6e34cc75c54b 220 SUPERFAMILY SSF53474 8 219 1.32E-37 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS04800 f8a06181cb5f52afddcc6e34cc75c54b 220 Pfam PF01738 Dienelactone hydrolase family 35 202 8.2E-8 T 11-11-2016 IPR002925 Dienelactone hydrolase GO:0016787 AUP74_RS04800 f8a06181cb5f52afddcc6e34cc75c54b 220 Gene3D G3DSA:3.40.50.1820 10 219 1.7E-51 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS15355 1904f8e20ca7625fb7c5750b5b7d3eab 251 SUPERFAMILY SSF57863 93 169 3.66E-8 T 11-11-2016 AUP74_RS15355 1904f8e20ca7625fb7c5750b5b7d3eab 251 Hamap MF_00201 DNA repair protein RecO [recO]. 5 247 19.756 T 11-11-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 AUP74_RS15355 1904f8e20ca7625fb7c5750b5b7d3eab 251 SUPERFAMILY SSF50249 8 79 1.71E-14 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS15355 1904f8e20ca7625fb7c5750b5b7d3eab 251 Pfam PF02565 Recombination protein O C terminal 87 242 2.2E-15 T 11-11-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 AUP74_RS15355 1904f8e20ca7625fb7c5750b5b7d3eab 251 Pfam PF11967 Recombination protein O N terminal 9 80 2.9E-20 T 11-11-2016 IPR022572 DNA replication/recombination mediator RecO, N-terminal AUP74_RS15355 1904f8e20ca7625fb7c5750b5b7d3eab 251 Gene3D G3DSA:2.40.50.140 11 82 4.6E-10 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS15355 1904f8e20ca7625fb7c5750b5b7d3eab 251 TIGRFAM TIGR00613 reco: DNA repair protein RecO 13 246 3.6E-26 T 11-11-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 AUP74_RS01155 7d1e5653e5a2c0acffccd8159d84adc4 427 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 11-11-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 AUP74_RS01155 7d1e5653e5a2c0acffccd8159d84adc4 427 SUPERFAMILY SSF51230 2 90 3.14E-14 T 11-11-2016 IPR011053 Single hybrid motif AUP74_RS01155 7d1e5653e5a2c0acffccd8159d84adc4 427 SUPERFAMILY SSF47005 122 162 3.01E-11 T 11-11-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 AUP74_RS01155 7d1e5653e5a2c0acffccd8159d84adc4 427 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 202 426 3.4E-74 T 11-11-2016 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 AUP74_RS01155 7d1e5653e5a2c0acffccd8159d84adc4 427 Pfam PF02817 e3 binding domain 123 157 1.5E-14 T 11-11-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 AUP74_RS01155 7d1e5653e5a2c0acffccd8159d84adc4 427 Pfam PF00364 Biotin-requiring enzyme 12 75 9.7E-11 T 11-11-2016 IPR000089 Biotin/lipoyl attachment AUP74_RS01155 7d1e5653e5a2c0acffccd8159d84adc4 427 SUPERFAMILY SSF52777 192 427 4.36E-75 T 11-11-2016 AUP74_RS01155 7d1e5653e5a2c0acffccd8159d84adc4 427 Gene3D G3DSA:3.30.559.10 190 426 7.9E-80 T 11-11-2016 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 AUP74_RS01155 7d1e5653e5a2c0acffccd8159d84adc4 427 Gene3D G3DSA:2.40.50.100 3 94 3.6E-16 T 11-11-2016 AUP74_RS01155 7d1e5653e5a2c0acffccd8159d84adc4 427 Gene3D G3DSA:4.10.320.10 121 166 2.7E-17 T 11-11-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 AUP74_RS10330 325f1335401d03d79e9c129fd31cb9e6 94 Gene3D G3DSA:1.10.760.10 16 91 9.8E-28 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS10330 325f1335401d03d79e9c129fd31cb9e6 94 SUPERFAMILY SSF46626 20 87 2.9E-14 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS10330 325f1335401d03d79e9c129fd31cb9e6 94 PRINTS PR00607 Class IE cytochrome C signature 64 76 2.2E-10 T 11-11-2016 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 AUP74_RS10330 325f1335401d03d79e9c129fd31cb9e6 94 PRINTS PR00607 Class IE cytochrome C signature 79 90 2.2E-10 T 11-11-2016 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 AUP74_RS10330 325f1335401d03d79e9c129fd31cb9e6 94 PRINTS PR00607 Class IE cytochrome C signature 25 36 2.2E-10 T 11-11-2016 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 AUP74_RS10330 325f1335401d03d79e9c129fd31cb9e6 94 PRINTS PR00607 Class IE cytochrome C signature 36 46 2.2E-10 T 11-11-2016 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 AUP74_RS10330 325f1335401d03d79e9c129fd31cb9e6 94 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 14 86 2.5E-14 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS01545 0ce8eafb83b36507ae557ad0a4f94516 156 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 17 152 2.9E-54 T 11-11-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AUP74_RS01545 0ce8eafb83b36507ae557ad0a4f94516 156 SUPERFAMILY SSF52121 7 156 1.03E-58 T 11-11-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AUP74_RS01545 0ce8eafb83b36507ae557ad0a4f94516 156 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 11 156 30.207 T 11-11-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AUP74_RS01545 0ce8eafb83b36507ae557ad0a4f94516 156 Gene3D G3DSA:3.40.50.960 5 153 9.9E-62 T 11-11-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AUP74_RS01545 0ce8eafb83b36507ae557ad0a4f94516 156 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 17 152 1.7E-52 T 11-11-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AUP74_RS04230 71ede06157584e0aa7478ec8eebaf605 138 Gene3D G3DSA:1.10.260.40 3 66 8.4E-16 T 11-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AUP74_RS04230 71ede06157584e0aa7478ec8eebaf605 138 Pfam PF01381 Helix-turn-helix 3 56 2.7E-14 T 11-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AUP74_RS04230 71ede06157584e0aa7478ec8eebaf605 138 SMART SM00530 2 56 4.4E-13 T 11-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AUP74_RS04230 71ede06157584e0aa7478ec8eebaf605 138 SUPERFAMILY SSF47413 3 58 3.22E-13 T 11-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AUP74_RS03135 66f57815b8ff63a1bf79d00e4ada707a 214 Gene3D G3DSA:1.10.357.10 19 206 1.7E-40 T 11-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 AUP74_RS03135 66f57815b8ff63a1bf79d00e4ada707a 214 SUPERFAMILY SSF48498 106 206 4.75E-10 T 11-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AUP74_RS03135 66f57815b8ff63a1bf79d00e4ada707a 214 SUPERFAMILY SSF46689 18 98 7.18E-17 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS03135 66f57815b8ff63a1bf79d00e4ada707a 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 75 1.8E-13 T 11-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AUP74_RS03135 66f57815b8ff63a1bf79d00e4ada707a 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 1.2E-7 T 11-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AUP74_RS03135 66f57815b8ff63a1bf79d00e4ada707a 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 51 74 1.2E-7 T 11-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AUP74_RS04005 81cce2cb8e42730af9a9fbb5edb609ac 769 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 406 420 6.0E-20 T 11-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS04005 81cce2cb8e42730af9a9fbb5edb609ac 769 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 511 524 6.0E-20 T 11-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS04005 81cce2cb8e42730af9a9fbb5edb609ac 769 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 540 555 6.0E-20 T 11-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS04005 81cce2cb8e42730af9a9fbb5edb609ac 769 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 477 496 6.0E-20 T 11-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS04005 81cce2cb8e42730af9a9fbb5edb609ac 769 Gene3D G3DSA:3.40.120.10 314 438 8.8E-31 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS04005 81cce2cb8e42730af9a9fbb5edb609ac 769 Gene3D G3DSA:3.30.310.50 677 766 4.6E-26 T 11-11-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS04005 81cce2cb8e42730af9a9fbb5edb609ac 769 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 566 674 6.8E-25 T 11-11-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS04005 81cce2cb8e42730af9a9fbb5edb609ac 769 Gene3D G3DSA:3.40.120.10 480 555 2.2E-31 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS04005 81cce2cb8e42730af9a9fbb5edb609ac 769 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 464 558 9.7E-25 T 11-11-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS04005 81cce2cb8e42730af9a9fbb5edb609ac 769 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 317 445 3.8E-31 T 11-11-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS04005 81cce2cb8e42730af9a9fbb5edb609ac 769 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 407 416 - T 11-11-2016 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS04005 81cce2cb8e42730af9a9fbb5edb609ac 769 SUPERFAMILY SSF53738 565 671 3.49E-35 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS04005 81cce2cb8e42730af9a9fbb5edb609ac 769 SUPERFAMILY SSF55957 674 762 1.07E-20 T 11-11-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS04005 81cce2cb8e42730af9a9fbb5edb609ac 769 SUPERFAMILY SSF53738 315 439 7.85E-34 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS04005 81cce2cb8e42730af9a9fbb5edb609ac 769 Gene3D G3DSA:3.40.120.10 559 674 2.5E-44 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS04005 81cce2cb8e42730af9a9fbb5edb609ac 769 SUPERFAMILY SSF53738 461 561 1.53E-28 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS04005 81cce2cb8e42730af9a9fbb5edb609ac 769 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 684 751 1.2E-9 T 11-11-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS05540 9d5aaa5a90de52de3b3e536b5eab3e46 392 Gene3D G3DSA:3.80.30.20 14 218 9.7E-33 T 11-11-2016 IPR023404 Radical SAM, alpha/beta horseshoe AUP74_RS05540 9d5aaa5a90de52de3b3e536b5eab3e46 392 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 14 354 4.3E-108 T 11-11-2016 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 AUP74_RS05540 9d5aaa5a90de52de3b3e536b5eab3e46 392 SMART SM00729 13 227 1.9E-51 T 11-11-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 AUP74_RS05540 9d5aaa5a90de52de3b3e536b5eab3e46 392 Pfam PF04055 Radical SAM superfamily 18 185 1.7E-18 T 11-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 AUP74_RS05540 9d5aaa5a90de52de3b3e536b5eab3e46 392 SUPERFAMILY SSF102114 12 389 2.35E-104 T 11-11-2016 AUP74_RS14735 baa296101da289dae220cc5d4ec05fe9 644 Gene3D G3DSA:3.30.54.20 131 186 2.8E-22 T 11-11-2016 AUP74_RS14735 baa296101da289dae220cc5d4ec05fe9 644 PRINTS PR01047 Threonyl-tRNA synthetase signature 361 384 1.8E-51 T 11-11-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AUP74_RS14735 baa296101da289dae220cc5d4ec05fe9 644 PRINTS PR01047 Threonyl-tRNA synthetase signature 463 491 1.8E-51 T 11-11-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AUP74_RS14735 baa296101da289dae220cc5d4ec05fe9 644 PRINTS PR01047 Threonyl-tRNA synthetase signature 328 356 1.8E-51 T 11-11-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AUP74_RS14735 baa296101da289dae220cc5d4ec05fe9 644 PRINTS PR01047 Threonyl-tRNA synthetase signature 533 545 1.8E-51 T 11-11-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AUP74_RS14735 baa296101da289dae220cc5d4ec05fe9 644 PRINTS PR01047 Threonyl-tRNA synthetase signature 506 519 1.8E-51 T 11-11-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AUP74_RS14735 baa296101da289dae220cc5d4ec05fe9 644 SUPERFAMILY SSF55186 65 240 8.63E-69 T 11-11-2016 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 AUP74_RS14735 baa296101da289dae220cc5d4ec05fe9 644 SMART SM00863 169 218 5.1E-25 T 11-11-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 AUP74_RS14735 baa296101da289dae220cc5d4ec05fe9 644 Pfam PF03129 Anticodon binding domain 540 628 3.0E-20 T 11-11-2016 IPR004154 Anticodon-binding AUP74_RS14735 baa296101da289dae220cc5d4ec05fe9 644 SUPERFAMILY SSF81271 3 61 3.6E-14 T 11-11-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 AUP74_RS14735 baa296101da289dae220cc5d4ec05fe9 644 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 630 2.4E-225 T 11-11-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AUP74_RS14735 baa296101da289dae220cc5d4ec05fe9 644 Gene3D G3DSA:3.10.20.30 1 62 6.0E-18 T 11-11-2016 IPR012675 Beta-grasp domain AUP74_RS14735 baa296101da289dae220cc5d4ec05fe9 644 SUPERFAMILY SSF55681 242 525 8.62E-101 T 11-11-2016 AUP74_RS14735 baa296101da289dae220cc5d4ec05fe9 644 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 322 528 1.4E-44 T 11-11-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS14735 baa296101da289dae220cc5d4ec05fe9 644 SUPERFAMILY SSF52954 528 633 1.12E-30 T 11-11-2016 IPR004154 Anticodon-binding AUP74_RS14735 baa296101da289dae220cc5d4ec05fe9 644 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 169 218 1.0E-14 T 11-11-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 AUP74_RS14735 baa296101da289dae220cc5d4ec05fe9 644 Pfam PF02824 TGS domain 3 61 7.6E-9 T 11-11-2016 IPR004095 TGS KEGG: 00970+6.1.1.3 AUP74_RS14735 baa296101da289dae220cc5d4ec05fe9 644 Gene3D G3DSA:3.30.980.10 66 129 4.3E-43 T 11-11-2016 AUP74_RS14735 baa296101da289dae220cc5d4ec05fe9 644 Gene3D G3DSA:3.30.980.10 187 222 4.3E-43 T 11-11-2016 AUP74_RS14735 baa296101da289dae220cc5d4ec05fe9 644 Gene3D G3DSA:3.40.50.800 530 634 1.4E-32 T 11-11-2016 IPR004154 Anticodon-binding AUP74_RS14735 baa296101da289dae220cc5d4ec05fe9 644 Gene3D G3DSA:3.30.930.10 241 528 1.1E-121 T 11-11-2016 AUP74_RS14735 baa296101da289dae220cc5d4ec05fe9 644 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 633 34.443 T 11-11-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AUP74_RS13115 e366923c65e27c900e1f80977bd88105 688 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 24 508 7.2E-182 T 11-11-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 AUP74_RS13115 e366923c65e27c900e1f80977bd88105 688 ProSitePatterns PS01303 BCCT family of transporters signature. 325 334 - T 11-11-2016 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 AUP74_RS13115 e366923c65e27c900e1f80977bd88105 688 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 62 508 6.3E-156 T 11-11-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 AUP74_RS10495 878ab3f3c4cfff17d849c875a0832c5e 176 Gene3D G3DSA:3.30.70.260 89 171 1.1E-20 T 11-11-2016 AUP74_RS10495 878ab3f3c4cfff17d849c875a0832c5e 176 Pfam PF13740 ACT domain 3 70 4.1E-16 T 11-11-2016 AUP74_RS10495 878ab3f3c4cfff17d849c875a0832c5e 176 Pfam PF13291 ACT domain 88 160 1.9E-6 T 11-11-2016 IPR002912 ACT domain GO:0008152|GO:0016597 AUP74_RS10495 878ab3f3c4cfff17d849c875a0832c5e 176 SUPERFAMILY SSF55021 1 69 1.03E-11 T 11-11-2016 AUP74_RS10495 878ab3f3c4cfff17d849c875a0832c5e 176 Gene3D G3DSA:3.30.70.260 1 75 2.3E-20 T 11-11-2016 AUP74_RS10495 878ab3f3c4cfff17d849c875a0832c5e 176 SUPERFAMILY SSF55021 88 167 6.11E-15 T 11-11-2016 AUP74_RS10495 878ab3f3c4cfff17d849c875a0832c5e 176 PIRSF PIRSF028103 1 173 5.5E-44 T 11-11-2016 IPR016867 Glycine cleavage system transcriptional repressor GO:0006355 AUP74_RS13060 1a64d34cff63ba73d2d67bb7ff01290b 78 SUPERFAMILY SSF47336 2 77 5.37E-24 T 11-11-2016 IPR009081 Phosphopantetheine binding ACP domain AUP74_RS13060 1a64d34cff63ba73d2d67bb7ff01290b 78 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 23.063 T 11-11-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS13060 1a64d34cff63ba73d2d67bb7ff01290b 78 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 11-11-2016 IPR006162 Phosphopantetheine attachment site AUP74_RS13060 1a64d34cff63ba73d2d67bb7ff01290b 78 Gene3D G3DSA:1.10.1200.10 3 76 4.4E-36 T 11-11-2016 IPR009081 Phosphopantetheine binding ACP domain AUP74_RS13060 1a64d34cff63ba73d2d67bb7ff01290b 78 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 1 76 4.2E-37 T 11-11-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS13060 1a64d34cff63ba73d2d67bb7ff01290b 78 Pfam PF00550 Phosphopantetheine attachment site 6 73 3.8E-17 T 11-11-2016 IPR009081 Phosphopantetheine binding ACP domain AUP74_RS10630 5f6eb3da7b03680b5055b58df2cf014e 173 Pfam PF03729 Short repeat of unknown function (DUF308) 13 82 3.8E-10 T 11-11-2016 IPR005325 Protein of unknown function DUF308, membrane AUP74_RS10630 5f6eb3da7b03680b5055b58df2cf014e 173 Pfam PF03729 Short repeat of unknown function (DUF308) 70 137 3.9E-9 T 11-11-2016 IPR005325 Protein of unknown function DUF308, membrane AUP74_RS13805 f6c64306d517725ff2b0db476599c683 229 SUPERFAMILY SSF52833 3 80 1.79E-20 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS13805 f6c64306d517725ff2b0db476599c683 229 SUPERFAMILY SSF47616 80 198 2.7E-18 T 11-11-2016 IPR010987 Glutathione S-transferase, C-terminal-like AUP74_RS13805 f6c64306d517725ff2b0db476599c683 229 Gene3D G3DSA:1.20.1050.10 87 203 1.0E-33 T 11-11-2016 IPR010987 Glutathione S-transferase, C-terminal-like AUP74_RS13805 f6c64306d517725ff2b0db476599c683 229 Pfam PF13410 Glutathione S-transferase, C-terminal domain 126 197 1.8E-6 T 11-11-2016 AUP74_RS13805 f6c64306d517725ff2b0db476599c683 229 Pfam PF13417 Glutathione S-transferase, N-terminal domain 10 80 1.1E-13 T 11-11-2016 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 AUP74_RS13805 f6c64306d517725ff2b0db476599c683 229 Gene3D G3DSA:3.40.30.10 10 80 6.2E-19 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS15165 078e763d17d4e84dee75e4b6a172a480 265 SUPERFAMILY SSF52096 8 237 8.56E-67 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS15165 078e763d17d4e84dee75e4b6a172a480 265 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 106 126 - T 11-11-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 AUP74_RS15165 078e763d17d4e84dee75e4b6a172a480 265 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 237 4.4E-46 T 11-11-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 AUP74_RS15165 078e763d17d4e84dee75e4b6a172a480 265 Gene3D G3DSA:3.90.226.10 5 253 1.5E-71 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS15940 5f84b625c9e52a042c4916227eb75d8a 600 Gene3D G3DSA:1.20.140.10 284 457 8.3E-45 T 11-11-2016 AUP74_RS15940 5f84b625c9e52a042c4916227eb75d8a 600 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 471 595 1.2E-32 T 11-11-2016 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain AUP74_RS15940 5f84b625c9e52a042c4916227eb75d8a 600 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 285 452 6.3E-18 T 11-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AUP74_RS15940 5f84b625c9e52a042c4916227eb75d8a 600 Gene3D G3DSA:1.10.540.10 40 157 2.1E-12 T 11-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 AUP74_RS15940 5f84b625c9e52a042c4916227eb75d8a 600 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 269 1.4E-15 T 11-11-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 AUP74_RS15940 5f84b625c9e52a042c4916227eb75d8a 600 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 40 156 3.3E-9 T 11-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 AUP74_RS15940 5f84b625c9e52a042c4916227eb75d8a 600 SUPERFAMILY SSF56645 39 281 1.57E-48 T 11-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 AUP74_RS15940 5f84b625c9e52a042c4916227eb75d8a 600 Gene3D G3DSA:2.40.110.10 160 281 1.3E-23 T 11-11-2016 AUP74_RS15940 5f84b625c9e52a042c4916227eb75d8a 600 SUPERFAMILY SSF47203 289 457 1.19E-37 T 11-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AUP74_RS15940 5f84b625c9e52a042c4916227eb75d8a 600 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 6 34 3.9E-8 T 11-11-2016 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria AUP74_RS15680 22b82ccb01c6e82f1490749b539d472b 118 Pfam PF03960 ArsC family 5 111 3.4E-12 T 11-11-2016 IPR006660 Arsenate reductase-like AUP74_RS15680 22b82ccb01c6e82f1490749b539d472b 118 Gene3D G3DSA:3.40.30.10 1 113 2.6E-39 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS15680 22b82ccb01c6e82f1490749b539d472b 118 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 2 112 9.1E-29 T 11-11-2016 IPR006504 Transcriptional regulator Spx/MgsR AUP74_RS15680 22b82ccb01c6e82f1490749b539d472b 118 SUPERFAMILY SSF52833 1 113 1.36E-30 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS09120 11587b115b45ee5b41b67222d45095e6 174 SUPERFAMILY SSF46565 6 78 5.36E-18 T 11-11-2016 IPR001623 DnaJ domain AUP74_RS09120 11587b115b45ee5b41b67222d45095e6 174 Pfam PF07743 HSCB C-terminal oligomerisation domain 91 166 1.2E-15 T 11-11-2016 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020 AUP74_RS09120 11587b115b45ee5b41b67222d45095e6 174 SUPERFAMILY SSF47144 84 174 2.09E-19 T 11-11-2016 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020 AUP74_RS09120 11587b115b45ee5b41b67222d45095e6 174 Hamap MF_00682 Co-chaperone protein HscB [hscB]. 5 173 22.126 T 11-11-2016 IPR004640 Co-chaperone Hsc20 GO:0006457|GO:0051087 Reactome: R-HSA-1268020 AUP74_RS09120 11587b115b45ee5b41b67222d45095e6 174 Gene3D G3DSA:1.20.1280.20 85 174 8.0E-22 T 11-11-2016 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020 AUP74_RS09120 11587b115b45ee5b41b67222d45095e6 174 SMART SM00271 5 70 5.8E-9 T 11-11-2016 IPR001623 DnaJ domain AUP74_RS09120 11587b115b45ee5b41b67222d45095e6 174 Pfam PF00226 DnaJ domain 6 74 5.0E-8 T 11-11-2016 IPR001623 DnaJ domain AUP74_RS09120 11587b115b45ee5b41b67222d45095e6 174 TIGRFAM TIGR00714 hscB: Fe-S protein assembly co-chaperone HscB 17 172 3.1E-34 T 11-11-2016 IPR004640 Co-chaperone Hsc20 GO:0006457|GO:0051087 Reactome: R-HSA-1268020 AUP74_RS09120 11587b115b45ee5b41b67222d45095e6 174 Gene3D G3DSA:1.10.287.110 2 77 5.0E-26 T 11-11-2016 IPR001623 DnaJ domain AUP74_RS16500 ccd73d26018723b4341f2ecf98c4d4fc 107 SUPERFAMILY SSF159894 5 101 4.18E-14 T 11-11-2016 AUP74_RS16500 ccd73d26018723b4341f2ecf98c4d4fc 107 Pfam PF04993 TfoX N-terminal domain 13 101 7.7E-15 T 11-11-2016 IPR007076 TfoX, N-terminal AUP74_RS16500 ccd73d26018723b4341f2ecf98c4d4fc 107 Gene3D G3DSA:3.30.1460.30 5 77 1.4E-6 T 11-11-2016 IPR007076 TfoX, N-terminal AUP74_RS13430 1acadc7494ab0ea2b05c7737cb1f451e 325 Pfam PF08003 Protein of unknown function (DUF1698) 15 323 5.3E-133 T 11-11-2016 IPR027555 tRNA (mo5U34)-methyltransferase-like AUP74_RS13430 1acadc7494ab0ea2b05c7737cb1f451e 325 Hamap MF_01590 tRNA U34 carboxymethyltransferase [cmoB]. 13 324 51.972 T 11-11-2016 IPR010017 tRNA U34 carboxymethyltransferase GO:0002098|GO:0016765 AUP74_RS13430 1acadc7494ab0ea2b05c7737cb1f451e 325 SUPERFAMILY SSF53335 93 324 7.23E-39 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS13430 1acadc7494ab0ea2b05c7737cb1f451e 325 Gene3D G3DSA:3.40.50.150 102 311 9.4E-30 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS13430 1acadc7494ab0ea2b05c7737cb1f451e 325 TIGRFAM TIGR00452 TIGR00452: tRNA (mo5U34)-methyltransferase 16 323 1.9E-141 T 11-11-2016 IPR010017 tRNA U34 carboxymethyltransferase GO:0002098|GO:0016765 AUP74_RS04590 d6726682464e0f2de69e3339469113ce 187 SUPERFAMILY SSF55821 8 187 2.47E-47 T 11-11-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain AUP74_RS04590 d6726682464e0f2de69e3339469113ce 187 Gene3D G3DSA:3.90.870.10 8 187 6.7E-50 T 11-11-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain AUP74_RS04590 d6726682464e0f2de69e3339469113ce 187 Pfam PF01300 Telomere recombination 14 187 4.6E-37 T 11-11-2016 IPR006070 YrdC-like domain GO:0003725 AUP74_RS04590 d6726682464e0f2de69e3339469113ce 187 Hamap MF_01852 Threonylcarbamoyl-AMP synthase [tsaC]. 5 185 35.233 T 11-11-2016 IPR023535 Threonylcarbamoyl-AMP synthase GO:0002949|GO:0005524 AUP74_RS02600 a24d671a2a2e59629a5007b2892bb661 429 PIRSF PIRSF005353 1 429 5.1E-181 T 11-11-2016 IPR026033 Purine permease PbuG-like AUP74_RS02600 a24d671a2a2e59629a5007b2892bb661 429 Pfam PF00860 Permease family 17 391 4.2E-54 T 11-11-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 AUP74_RS11920 4b572303d65442c14af770aaf7a8584b 403 TIGRFAM TIGR01937 nqrB: NADH:ubiquinone oxidoreductase, Na(+)-translocating, B subunit 2 399 2.8E-172 T 11-11-2016 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 AUP74_RS11920 4b572303d65442c14af770aaf7a8584b 403 Hamap MF_00426 Na(+)-translocating NADH-quinone reductase subunit B [nqrB]. 1 403 35.893 T 11-11-2016 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 AUP74_RS11920 4b572303d65442c14af770aaf7a8584b 403 Pfam PF03116 NQR2, RnfD, RnfE family 40 396 1.7E-102 T 11-11-2016 IPR004338 NADH-quinone reductase NQR2/RnfD GO:0006810|GO:0016020 AUP74_RS11920 4b572303d65442c14af770aaf7a8584b 403 PIRSF PIRSF016055 1 403 1.7E-189 T 11-11-2016 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 AUP74_RS02645 982fd0d5a77061d1912cd0ef7ecbb662 497 Pfam PF00171 Aldehyde dehydrogenase family 16 477 2.6E-141 T 11-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 AUP74_RS02645 982fd0d5a77061d1912cd0ef7ecbb662 497 Gene3D G3DSA:3.40.605.10 4 258 2.5E-88 T 11-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AUP74_RS02645 982fd0d5a77061d1912cd0ef7ecbb662 497 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 273 284 - T 11-11-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 AUP74_RS02645 982fd0d5a77061d1912cd0ef7ecbb662 497 Gene3D G3DSA:3.40.309.10 259 442 5.0E-68 T 11-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 AUP74_RS02645 982fd0d5a77061d1912cd0ef7ecbb662 497 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 4 481 6.5E-206 T 11-11-2016 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 AUP74_RS02645 982fd0d5a77061d1912cd0ef7ecbb662 497 SUPERFAMILY SSF53720 3 482 7.72E-147 T 11-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AUP74_RS10255 2e505b6f09f1283913513b6d42c5980f 279 Pfam PF12146 Serine aminopeptidase, S33 22 252 7.2E-68 T 11-11-2016 IPR022742 Serine aminopeptidase, S33 AUP74_RS10255 2e505b6f09f1283913513b6d42c5980f 279 SUPERFAMILY SSF53474 5 269 1.04E-37 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS10255 2e505b6f09f1283913513b6d42c5980f 279 Gene3D G3DSA:3.40.50.1820 7 267 4.9E-45 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS15560 e5deac5cf748650deb0c6d850177ee5c 179 Gene3D G3DSA:2.30.30.240 104 179 3.2E-25 T 11-11-2016 AUP74_RS15560 e5deac5cf748650deb0c6d850177ee5c 179 SUPERFAMILY SSF50346 104 179 2.35E-16 T 11-11-2016 IPR011033 PRC-barrel-like AUP74_RS15560 e5deac5cf748650deb0c6d850177ee5c 179 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 12 178 2.2E-48 T 11-11-2016 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 AUP74_RS15560 e5deac5cf748650deb0c6d850177ee5c 179 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 11 179 23.107 T 11-11-2016 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 AUP74_RS15560 e5deac5cf748650deb0c6d850177ee5c 179 Gene3D G3DSA:2.40.30.60 8 97 1.9E-29 T 11-11-2016 IPR002676 RimM protein GO:0006364 AUP74_RS15560 e5deac5cf748650deb0c6d850177ee5c 179 Pfam PF01782 RimM N-terminal domain 14 94 3.5E-23 T 11-11-2016 IPR002676 RimM protein GO:0006364 AUP74_RS15560 e5deac5cf748650deb0c6d850177ee5c 179 Pfam PF05239 PRC-barrel domain 101 174 4.7E-5 T 11-11-2016 IPR027275 PRC-barrel domain AUP74_RS15560 e5deac5cf748650deb0c6d850177ee5c 179 SUPERFAMILY SSF50447 10 97 8.47E-22 T 11-11-2016 IPR009000 Translation protein, beta-barrel domain AUP74_RS09455 002ac86318fced1ec2df5a0f6e816220 484 Gene3D G3DSA:1.20.210.10 15 475 2.4E-71 T 11-11-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS09455 002ac86318fced1ec2df5a0f6e816220 484 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 209 264 - T 11-11-2016 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS09455 002ac86318fced1ec2df5a0f6e816220 484 TIGRFAM TIGR00780 ccoN: cytochrome c oxidase, cbb3-type, subunit I 13 478 2.7E-226 T 11-11-2016 IPR004677 Cytochrome c oxidase cbb3-type, subunit I GO:0004129|GO:0045278|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 AUP74_RS09455 002ac86318fced1ec2df5a0f6e816220 484 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 17 448 1.3E-110 T 11-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS09455 002ac86318fced1ec2df5a0f6e816220 484 SUPERFAMILY SSF81442 14 471 1.57E-123 T 11-11-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS10900 e5afe663bf36e9677500b8b6f67501a1 661 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 160 182 5.8E-92 T 11-11-2016 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 AUP74_RS10900 e5afe663bf36e9677500b8b6f67501a1 661 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 132 149 5.8E-92 T 11-11-2016 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 AUP74_RS10900 e5afe663bf36e9677500b8b6f67501a1 661 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 245 265 5.8E-92 T 11-11-2016 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 AUP74_RS10900 e5afe663bf36e9677500b8b6f67501a1 661 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 275 295 5.8E-92 T 11-11-2016 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 AUP74_RS10900 e5afe663bf36e9677500b8b6f67501a1 661 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 311 330 5.8E-92 T 11-11-2016 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 AUP74_RS10900 e5afe663bf36e9677500b8b6f67501a1 661 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 80 106 5.8E-92 T 11-11-2016 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 AUP74_RS10900 e5afe663bf36e9677500b8b6f67501a1 661 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 211 237 5.8E-92 T 11-11-2016 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 AUP74_RS10900 e5afe663bf36e9677500b8b6f67501a1 661 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 295 311 5.8E-92 T 11-11-2016 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 AUP74_RS10900 e5afe663bf36e9677500b8b6f67501a1 661 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 190 205 4.8E-49 T 11-11-2016 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 AUP74_RS10900 e5afe663bf36e9677500b8b6f67501a1 661 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 113 136 4.8E-49 T 11-11-2016 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 AUP74_RS10900 e5afe663bf36e9677500b8b6f67501a1 661 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 634 647 4.8E-49 T 11-11-2016 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 AUP74_RS10900 e5afe663bf36e9677500b8b6f67501a1 661 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 314 329 4.8E-49 T 11-11-2016 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 AUP74_RS10900 e5afe663bf36e9677500b8b6f67501a1 661 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 4 28 4.8E-49 T 11-11-2016 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 AUP74_RS10900 e5afe663bf36e9677500b8b6f67501a1 661 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 352 369 4.8E-49 T 11-11-2016 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 AUP74_RS10900 e5afe663bf36e9677500b8b6f67501a1 661 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 395 414 4.8E-49 T 11-11-2016 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 AUP74_RS10900 e5afe663bf36e9677500b8b6f67501a1 661 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 316 641 2.2E-121 T 11-11-2016 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal AUP74_RS10900 e5afe663bf36e9677500b8b6f67501a1 661 Pfam PF01578 Cytochrome C assembly protein 89 296 4.3E-52 T 11-11-2016 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 AUP74_RS10900 e5afe663bf36e9677500b8b6f67501a1 661 TIGRFAM TIGR00353 nrfE: cytochrome c-type biogenesis protein CcmF 54 644 7.8E-225 T 11-11-2016 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 AUP74_RS08720 bfff73bae094d49c62931457cd9cf626 357 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 342 2.9E-151 T 11-11-2016 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 AUP74_RS08720 bfff73bae094d49c62931457cd9cf626 357 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 329 1.0E-95 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS08720 bfff73bae094d49c62931457cd9cf626 357 SUPERFAMILY SSF51735 1 348 1.94E-95 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS08720 bfff73bae094d49c62931457cd9cf626 357 Gene3D G3DSA:3.40.50.720 1 189 1.0E-65 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS08720 bfff73bae094d49c62931457cd9cf626 357 Gene3D G3DSA:3.90.25.10 190 343 1.3E-55 T 11-11-2016 AUP74_RS07055 0b73a5de58e3b2f4f202bf0ffd73ac57 690 Pfam PF00512 His Kinase A (phospho-acceptor) domain 457 519 2.7E-10 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS07055 0b73a5de58e3b2f4f202bf0ffd73ac57 690 SUPERFAMILY SSF55874 511 675 2.75E-29 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS07055 0b73a5de58e3b2f4f202bf0ffd73ac57 690 SMART SM00387 565 677 9.2E-22 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS07055 0b73a5de58e3b2f4f202bf0ffd73ac57 690 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 568 674 5.1E-13 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS07055 0b73a5de58e3b2f4f202bf0ffd73ac57 690 Gene3D G3DSA:3.30.565.10 525 674 3.0E-27 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS07055 0b73a5de58e3b2f4f202bf0ffd73ac57 690 Gene3D G3DSA:1.10.287.130 450 513 1.6E-9 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS07055 0b73a5de58e3b2f4f202bf0ffd73ac57 690 SUPERFAMILY SSF47384 439 520 8.24E-13 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS07055 0b73a5de58e3b2f4f202bf0ffd73ac57 690 SMART SM00388 456 521 2.8E-12 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS07055 0b73a5de58e3b2f4f202bf0ffd73ac57 690 SUPERFAMILY SSF49344 78 207 4.32E-6 T 11-11-2016 AUP74_RS08425 95d048bbb84fbe139ca0bd37b9b9925f 111 Pfam PF02410 Ribosomal silencing factor during starvation 8 102 5.5E-27 T 11-11-2016 AUP74_RS08425 95d048bbb84fbe139ca0bd37b9b9925f 111 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 6 102 6.4E-38 T 11-11-2016 IPR004394 Protein Iojap/ribosomal silencing factor RsfS AUP74_RS08425 95d048bbb84fbe139ca0bd37b9b9925f 111 SUPERFAMILY SSF81301 3 106 1.39E-38 T 11-11-2016 AUP74_RS08425 95d048bbb84fbe139ca0bd37b9b9925f 111 Gene3D G3DSA:3.30.460.10 4 104 6.6E-37 T 11-11-2016 AUP74_RS08425 95d048bbb84fbe139ca0bd37b9b9925f 111 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 1 103 25.068 T 11-11-2016 IPR004394 Protein Iojap/ribosomal silencing factor RsfS AUP74_RS09975 092c8cc339f85678e59b0fe9cda01e8d 422 TIGRFAM TIGR01078 arcA: arginine deiminase 14 420 1.4E-149 T 11-11-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 AUP74_RS09975 092c8cc339f85678e59b0fe9cda01e8d 422 PRINTS PR01466 Bacterial arginine deiminase signature 10 30 2.1E-44 T 11-11-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 AUP74_RS09975 092c8cc339f85678e59b0fe9cda01e8d 422 PRINTS PR01466 Bacterial arginine deiminase signature 356 373 2.1E-44 T 11-11-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 AUP74_RS09975 092c8cc339f85678e59b0fe9cda01e8d 422 PRINTS PR01466 Bacterial arginine deiminase signature 376 390 2.1E-44 T 11-11-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 AUP74_RS09975 092c8cc339f85678e59b0fe9cda01e8d 422 PRINTS PR01466 Bacterial arginine deiminase signature 162 180 2.1E-44 T 11-11-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 AUP74_RS09975 092c8cc339f85678e59b0fe9cda01e8d 422 PRINTS PR01466 Bacterial arginine deiminase signature 190 205 2.1E-44 T 11-11-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 AUP74_RS09975 092c8cc339f85678e59b0fe9cda01e8d 422 PRINTS PR01466 Bacterial arginine deiminase signature 399 417 2.1E-44 T 11-11-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 AUP74_RS09975 092c8cc339f85678e59b0fe9cda01e8d 422 PIRSF PIRSF006356 1 420 5.2E-133 T 11-11-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 AUP74_RS09975 092c8cc339f85678e59b0fe9cda01e8d 422 SUPERFAMILY SSF55909 12 420 1.09E-127 T 11-11-2016 AUP74_RS09975 092c8cc339f85678e59b0fe9cda01e8d 422 Hamap MF_00242 Arginine deiminase [arcA]. 9 420 46.262 T 11-11-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 AUP74_RS09975 092c8cc339f85678e59b0fe9cda01e8d 422 Gene3D G3DSA:3.75.10.10 10 75 1.3E-121 T 11-11-2016 AUP74_RS09975 092c8cc339f85678e59b0fe9cda01e8d 422 Gene3D G3DSA:3.75.10.10 162 421 1.3E-121 T 11-11-2016 AUP74_RS09975 092c8cc339f85678e59b0fe9cda01e8d 422 Pfam PF02274 Amidinotransferase 26 417 3.7E-95 T 11-11-2016 AUP74_RS15605 57bcbd64905632d8165aa93e93906af9 351 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 227 261 1.3E-8 T 11-11-2016 IPR001451 Hexapeptide repeat AUP74_RS15605 57bcbd64905632d8165aa93e93906af9 351 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 150 184 5.6E-7 T 11-11-2016 IPR001451 Hexapeptide repeat AUP74_RS15605 57bcbd64905632d8165aa93e93906af9 351 Gene3D G3DSA:2.160.10.10 216 338 3.0E-24 T 11-11-2016 AUP74_RS15605 57bcbd64905632d8165aa93e93906af9 351 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 31 93 9.3E-20 T 11-11-2016 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 AUP74_RS15605 57bcbd64905632d8165aa93e93906af9 351 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 10 334 3.3E-105 T 11-11-2016 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 AUP74_RS15605 57bcbd64905632d8165aa93e93906af9 351 SUPERFAMILY SSF51161 37 323 2.43E-80 T 11-11-2016 IPR011004 Trimeric LpxA-like AUP74_RS15605 57bcbd64905632d8165aa93e93906af9 351 Gene3D G3DSA:2.160.10.10 112 215 8.9E-24 T 11-11-2016 AUP74_RS15605 57bcbd64905632d8165aa93e93906af9 351 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 10 331 35.594 T 11-11-2016 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 AUP74_RS15075 13a25004fe7de31780fdc1ecd62c9045 478 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 62 87 4.8E-21 T 11-11-2016 AUP74_RS15075 13a25004fe7de31780fdc1ecd62c9045 478 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 223 249 4.8E-21 T 11-11-2016 AUP74_RS15075 13a25004fe7de31780fdc1ecd62c9045 478 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 290 302 4.8E-21 T 11-11-2016 AUP74_RS15075 13a25004fe7de31780fdc1ecd62c9045 478 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 201 222 4.8E-21 T 11-11-2016 AUP74_RS15075 13a25004fe7de31780fdc1ecd62c9045 478 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 137 158 4.8E-21 T 11-11-2016 AUP74_RS15075 13a25004fe7de31780fdc1ecd62c9045 478 Pfam PF00361 Proton-conducting membrane transporter 115 378 1.7E-36 T 11-11-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS00980 3acc608e3095a7e12e211115fb0feee6 448 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 13 34 2.8E-8 T 11-11-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AUP74_RS00980 3acc608e3095a7e12e211115fb0feee6 448 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 42 61 2.8E-8 T 11-11-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AUP74_RS00980 3acc608e3095a7e12e211115fb0feee6 448 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 322 342 2.8E-8 T 11-11-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AUP74_RS00980 3acc608e3095a7e12e211115fb0feee6 448 SUPERFAMILY SSF161070 5 447 3.4E-111 T 11-11-2016 AUP74_RS00980 3acc608e3095a7e12e211115fb0feee6 448 Pfam PF00209 Sodium:neurotransmitter symporter family 5 125 3.8E-19 T 11-11-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AUP74_RS00980 3acc608e3095a7e12e211115fb0feee6 448 Pfam PF00209 Sodium:neurotransmitter symporter family 154 447 1.5E-27 T 11-11-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AUP74_RS08415 7d45b3bc61e5c3be0b4740c292ac1ce9 409 Pfam PF00171 Aldehyde dehydrogenase family 289 365 7.3E-7 T 11-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 AUP74_RS08415 7d45b3bc61e5c3be0b4740c292ac1ce9 409 Pfam PF00171 Aldehyde dehydrogenase family 63 278 6.3E-17 T 11-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 AUP74_RS08415 7d45b3bc61e5c3be0b4740c292ac1ce9 409 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 1 408 41.172 T 11-11-2016 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AUP74_RS08415 7d45b3bc61e5c3be0b4740c292ac1ce9 409 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 315 336 - T 11-11-2016 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AUP74_RS08415 7d45b3bc61e5c3be0b4740c292ac1ce9 409 PIRSF PIRSF000151 1 409 2.8E-176 T 11-11-2016 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 AUP74_RS08415 7d45b3bc61e5c3be0b4740c292ac1ce9 409 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 5 398 9.6E-147 T 11-11-2016 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AUP74_RS08415 7d45b3bc61e5c3be0b4740c292ac1ce9 409 SUPERFAMILY SSF53720 3 408 1.96E-117 T 11-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AUP74_RS08415 7d45b3bc61e5c3be0b4740c292ac1ce9 409 Gene3D G3DSA:3.40.605.10 2 216 6.0E-99 T 11-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AUP74_RS08415 7d45b3bc61e5c3be0b4740c292ac1ce9 409 Gene3D G3DSA:3.40.605.10 367 408 6.0E-99 T 11-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AUP74_RS08415 7d45b3bc61e5c3be0b4740c292ac1ce9 409 Gene3D G3DSA:3.40.309.10 219 366 7.6E-43 T 11-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 AUP74_RS12670 4cf1405f9e8651efb4d490de66d336a3 326 Gene3D G3DSA:3.40.50.920 196 320 3.5E-40 T 11-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 AUP74_RS12670 4cf1405f9e8651efb4d490de66d336a3 326 Pfam PF02779 Transketolase, pyrimidine binding domain 3 177 8.5E-43 T 11-11-2016 IPR005475 Transketolase-like, pyrimidine-binding domain AUP74_RS12670 4cf1405f9e8651efb4d490de66d336a3 326 Gene3D G3DSA:3.40.50.970 2 188 1.6E-75 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS12670 4cf1405f9e8651efb4d490de66d336a3 326 SMART SM00861 3 178 2.8E-59 T 11-11-2016 IPR005475 Transketolase-like, pyrimidine-binding domain AUP74_RS12670 4cf1405f9e8651efb4d490de66d336a3 326 SUPERFAMILY SSF52518 3 184 4.55E-63 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS12670 4cf1405f9e8651efb4d490de66d336a3 326 SUPERFAMILY SSF52922 189 322 1.44E-36 T 11-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 AUP74_RS12670 4cf1405f9e8651efb4d490de66d336a3 326 Pfam PF02780 Transketolase, C-terminal domain 194 314 2.6E-34 T 11-11-2016 IPR033248 Transketolase, C-terminal domain AUP74_RS11575 0d06b1e5179c036fb9551faa28382c66 242 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 4 201 5.4E-8 T 11-11-2016 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 AUP74_RS11575 0d06b1e5179c036fb9551faa28382c66 242 Gene3D G3DSA:3.60.21.10 173 204 3.5E-21 T 11-11-2016 IPR029052 Metallo-dependent phosphatase-like AUP74_RS11575 0d06b1e5179c036fb9551faa28382c66 242 Gene3D G3DSA:3.60.21.10 4 125 3.5E-21 T 11-11-2016 IPR029052 Metallo-dependent phosphatase-like AUP74_RS11575 0d06b1e5179c036fb9551faa28382c66 242 Hamap MF_00575 UDP-2,3-diacylglucosamine hydrolase [lpxH]. 1 241 115.772 T 11-11-2016 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 AUP74_RS11575 0d06b1e5179c036fb9551faa28382c66 242 TIGRFAM TIGR01854 lipid_A_lpxH: UDP-2,3-diacylglucosamine diphosphatase 3 231 6.0E-94 T 11-11-2016 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 AUP74_RS11575 0d06b1e5179c036fb9551faa28382c66 242 SUPERFAMILY SSF56300 2 123 2.76E-30 T 11-11-2016 IPR029052 Metallo-dependent phosphatase-like AUP74_RS11575 0d06b1e5179c036fb9551faa28382c66 242 SUPERFAMILY SSF56300 154 229 2.76E-30 T 11-11-2016 IPR029052 Metallo-dependent phosphatase-like AUP74_RS16485 36cc34d436426d3ef4bddd923f5db15a 292 Gene3D G3DSA:3.20.20.100 2 284 7.1E-96 T 11-11-2016 IPR023210 NADP-dependent oxidoreductase domain AUP74_RS16485 36cc34d436426d3ef4bddd923f5db15a 292 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 124 141 - T 11-11-2016 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 AUP74_RS16485 36cc34d436426d3ef4bddd923f5db15a 292 SUPERFAMILY SSF51430 2 276 1.24E-85 T 11-11-2016 IPR023210 NADP-dependent oxidoreductase domain AUP74_RS16485 36cc34d436426d3ef4bddd923f5db15a 292 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 43 60 - T 11-11-2016 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 AUP74_RS16485 36cc34d436426d3ef4bddd923f5db15a 292 Pfam PF00248 Aldo/keto reductase family 15 269 1.7E-54 T 11-11-2016 IPR023210 NADP-dependent oxidoreductase domain AUP74_RS16485 36cc34d436426d3ef4bddd923f5db15a 292 PRINTS PR00069 Aldo-keto reductase signature 158 187 1.3E-44 T 11-11-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AUP74_RS16485 36cc34d436426d3ef4bddd923f5db15a 292 PRINTS PR00069 Aldo-keto reductase signature 39 63 1.3E-44 T 11-11-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AUP74_RS16485 36cc34d436426d3ef4bddd923f5db15a 292 PRINTS PR00069 Aldo-keto reductase signature 94 112 1.3E-44 T 11-11-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AUP74_RS16485 36cc34d436426d3ef4bddd923f5db15a 292 PRINTS PR00069 Aldo-keto reductase signature 204 228 1.3E-44 T 11-11-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AUP74_RS16485 36cc34d436426d3ef4bddd923f5db15a 292 PRINTS PR00069 Aldo-keto reductase signature 124 141 1.3E-44 T 11-11-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AUP74_RS09165 b77f1ed2f212525c08ee123b765e9b33 411 SUPERFAMILY SSF55681 1 310 8.04E-102 T 11-11-2016 AUP74_RS09165 b77f1ed2f212525c08ee123b765e9b33 411 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 411 31.75 T 11-11-2016 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 AUP74_RS09165 b77f1ed2f212525c08ee123b765e9b33 411 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 1 400 1.8E-151 T 11-11-2016 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 AUP74_RS09165 b77f1ed2f212525c08ee123b765e9b33 411 PIRSF PIRSF001549 1 411 6.9E-120 T 11-11-2016 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 AUP74_RS09165 b77f1ed2f212525c08ee123b765e9b33 411 Gene3D G3DSA:3.30.930.10 210 312 1.2E-94 T 11-11-2016 AUP74_RS09165 b77f1ed2f212525c08ee123b765e9b33 411 Gene3D G3DSA:3.30.930.10 1 174 1.2E-94 T 11-11-2016 AUP74_RS09165 b77f1ed2f212525c08ee123b765e9b33 411 Pfam PF13393 Histidyl-tRNA synthetase 1 301 9.7E-49 T 11-11-2016 AUP74_RS09165 b77f1ed2f212525c08ee123b765e9b33 411 Pfam PF03129 Anticodon binding domain 323 410 5.2E-8 T 11-11-2016 IPR004154 Anticodon-binding AUP74_RS09165 b77f1ed2f212525c08ee123b765e9b33 411 SUPERFAMILY SSF52954 318 410 4.74E-18 T 11-11-2016 IPR004154 Anticodon-binding AUP74_RS09165 b77f1ed2f212525c08ee123b765e9b33 411 Gene3D G3DSA:3.40.50.800 317 410 3.4E-27 T 11-11-2016 IPR004154 Anticodon-binding AUP74_RS02760 702de3579f0983eac033b65abf114af1 437 Pfam PF00202 Aminotransferase class-III 17 432 1.2E-113 T 11-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AUP74_RS02760 702de3579f0983eac033b65abf114af1 437 SUPERFAMILY SSF53383 9 435 1.28E-117 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase AUP74_RS02760 702de3579f0983eac033b65abf114af1 437 Gene3D G3DSA:3.90.1150.10 338 435 9.0E-42 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS02760 702de3579f0983eac033b65abf114af1 437 Gene3D G3DSA:3.90.1150.10 3 58 9.0E-42 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS02760 702de3579f0983eac033b65abf114af1 437 Gene3D G3DSA:3.40.640.10 60 336 5.4E-83 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AUP74_RS04375 9edb12021c43ba383e47caad55631172 817 SUPERFAMILY SSF55486 76 232 8.1E-11 T 11-11-2016 AUP74_RS04375 9edb12021c43ba383e47caad55631172 817 Gene3D G3DSA:3.40.390.10 71 228 1.1E-9 T 11-11-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 AUP74_RS09985 b335b4bdc741c9db655e309a7b92ac61 417 Gene3D G3DSA:2.40.50.100 57 89 2.0E-18 T 11-11-2016 AUP74_RS09985 b335b4bdc741c9db655e309a7b92ac61 417 Gene3D G3DSA:2.40.50.100 165 196 2.0E-18 T 11-11-2016 AUP74_RS09985 b335b4bdc741c9db655e309a7b92ac61 417 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 46 284 4.5E-16 T 11-11-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AUP74_RS09985 b335b4bdc741c9db655e309a7b92ac61 417 Gene3D G3DSA:1.20.1600.10 98 164 8.9E-4 T 11-11-2016 AUP74_RS09985 b335b4bdc741c9db655e309a7b92ac61 417 SUPERFAMILY SSF111369 45 288 1.44E-64 T 11-11-2016 AUP74_RS09985 b335b4bdc741c9db655e309a7b92ac61 417 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 31 367 1.9E-74 T 11-11-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 AUP74_RS11410 e09b960a599c231bb22dcd0c0eb09ad7 150 PRINTS PR00502 NUDIX hydrolase family signature 52 67 2.9E-5 T 11-11-2016 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AUP74_RS11410 e09b960a599c231bb22dcd0c0eb09ad7 150 PRINTS PR00502 NUDIX hydrolase family signature 38 52 2.9E-5 T 11-11-2016 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AUP74_RS11410 e09b960a599c231bb22dcd0c0eb09ad7 150 Pfam PF00293 NUDIX domain 9 130 1.3E-18 T 11-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 AUP74_RS11410 e09b960a599c231bb22dcd0c0eb09ad7 150 Gene3D G3DSA:3.90.79.10 12 134 2.1E-26 T 11-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 AUP74_RS11410 e09b960a599c231bb22dcd0c0eb09ad7 150 SUPERFAMILY SSF55811 11 141 7.31E-28 T 11-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 AUP74_RS11410 e09b960a599c231bb22dcd0c0eb09ad7 150 ProSitePatterns PS00893 Nudix box signature. 43 64 - T 11-11-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AUP74_RS14370 928668a71cdcde42587cbf5ca0fc6625 398 Pfam PF02515 CoA-transferase family III 7 363 1.4E-105 T 11-11-2016 IPR003673 CoA-transferase family III GO:0003824 AUP74_RS14370 928668a71cdcde42587cbf5ca0fc6625 398 Gene3D G3DSA:3.40.50.10540 310 398 5.5E-88 T 11-11-2016 IPR023606 CoA-transferase family III domain AUP74_RS14370 928668a71cdcde42587cbf5ca0fc6625 398 Gene3D G3DSA:3.40.50.10540 3 220 5.5E-88 T 11-11-2016 IPR023606 CoA-transferase family III domain AUP74_RS14370 928668a71cdcde42587cbf5ca0fc6625 398 SUPERFAMILY SSF89796 3 398 8.5E-112 T 11-11-2016 IPR023606 CoA-transferase family III domain AUP74_RS14370 928668a71cdcde42587cbf5ca0fc6625 398 Gene3D G3DSA:3.30.1540.10 232 309 6.9E-25 T 11-11-2016 AUP74_RS13765 b47484878ccbee41fea2c8765cd35aa0 161 SUPERFAMILY SSF54909 65 154 1.47E-23 T 11-11-2016 IPR011008 Dimeric alpha-beta barrel AUP74_RS13765 b47484878ccbee41fea2c8765cd35aa0 161 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 52 1.3E-17 T 11-11-2016 AUP74_RS13765 b47484878ccbee41fea2c8765cd35aa0 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 4.0E-12 T 11-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 AUP74_RS13765 b47484878ccbee41fea2c8765cd35aa0 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 4.0E-12 T 11-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 AUP74_RS13765 b47484878ccbee41fea2c8765cd35aa0 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 4.0E-12 T 11-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 AUP74_RS13765 b47484878ccbee41fea2c8765cd35aa0 161 Gene3D G3DSA:1.10.10.10 2 54 1.3E-21 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS13765 b47484878ccbee41fea2c8765cd35aa0 161 SUPERFAMILY SSF46785 3 64 2.0E-16 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS13765 b47484878ccbee41fea2c8765cd35aa0 161 SMART SM00344 5 114 4.1E-45 T 11-11-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AUP74_RS13765 b47484878ccbee41fea2c8765cd35aa0 161 Gene3D G3DSA:3.30.70.920 58 142 1.4E-33 T 11-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AUP74_RS13765 b47484878ccbee41fea2c8765cd35aa0 161 Pfam PF01037 Lrp/AsnC ligand binding domain 71 145 6.4E-27 T 11-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AUP74_RS00165 7d936d74e34c05aa03682718d9b2ba69 423 SUPERFAMILY SSF51735 157 310 3.51E-37 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS00165 7d936d74e34c05aa03682718d9b2ba69 423 PIRSF PIRSF000445 1 422 2.0E-155 T 11-11-2016 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AUP74_RS00165 7d936d74e34c05aa03682718d9b2ba69 423 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 413 31.122 T 11-11-2016 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AUP74_RS00165 7d936d74e34c05aa03682718d9b2ba69 423 Gene3D G3DSA:3.40.50.720 158 305 4.6E-38 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS00165 7d936d74e34c05aa03682718d9b2ba69 423 SUPERFAMILY SSF69075 312 413 1.83E-24 T 11-11-2016 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AUP74_RS00165 7d936d74e34c05aa03682718d9b2ba69 423 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 94 117 - T 11-11-2016 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AUP74_RS00165 7d936d74e34c05aa03682718d9b2ba69 423 SUPERFAMILY SSF69742 1 153 1.22E-46 T 11-11-2016 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AUP74_RS00165 7d936d74e34c05aa03682718d9b2ba69 423 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 316 411 4.2E-23 T 11-11-2016 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AUP74_RS00165 7d936d74e34c05aa03682718d9b2ba69 423 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 3 412 1.7E-137 T 11-11-2016 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AUP74_RS00165 7d936d74e34c05aa03682718d9b2ba69 423 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 151 6.0E-49 T 11-11-2016 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AUP74_RS00165 7d936d74e34c05aa03682718d9b2ba69 423 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 167 301 7.7E-48 T 11-11-2016 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase AUP74_RS11300 52a1b261b1f54c0c3648ab33d30c6ba9 579 TIGRFAM TIGR00815 sulP: sulfate permease 9 547 2.8E-127 T 11-11-2016 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 AUP74_RS11300 52a1b261b1f54c0c3648ab33d30c6ba9 579 Pfam PF00916 Sulfate permease family 22 399 4.9E-92 T 11-11-2016 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 AUP74_RS11300 52a1b261b1f54c0c3648ab33d30c6ba9 579 Gene3D G3DSA:3.30.750.24 453 548 1.2E-12 T 11-11-2016 IPR002645 STAS domain AUP74_RS11300 52a1b261b1f54c0c3648ab33d30c6ba9 579 Pfam PF01740 STAS domain 453 555 2.5E-13 T 11-11-2016 IPR002645 STAS domain AUP74_RS11300 52a1b261b1f54c0c3648ab33d30c6ba9 579 SUPERFAMILY SSF52091 451 553 1.45E-12 T 11-11-2016 IPR002645 STAS domain AUP74_RS03615 83b963daee80a3830969f7f91777d926 602 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 44 59 - T 11-11-2016 IPR031157 Tr-type G domain, conserved site AUP74_RS03615 83b963daee80a3830969f7f91777d926 602 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 134 1.9E-24 T 11-11-2016 IPR005225 Small GTP-binding protein domain GO:0005525 AUP74_RS03615 83b963daee80a3830969f7f91777d926 602 Pfam PF00679 Elongation factor G C-terminus 396 477 2.2E-22 T 11-11-2016 IPR000640 Translation elongation factor EFG, V domain AUP74_RS03615 83b963daee80a3830969f7f91777d926 602 SUPERFAMILY SSF50447 151 299 1.29E-35 T 11-11-2016 IPR009000 Translation protein, beta-barrel domain AUP74_RS03615 83b963daee80a3830969f7f91777d926 602 Gene3D G3DSA:3.30.70.240 400 478 3.8E-32 T 11-11-2016 IPR000640 Translation elongation factor EFG, V domain AUP74_RS03615 83b963daee80a3830969f7f91777d926 602 SUPERFAMILY SSF52540 3 207 9.55E-58 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03615 83b963daee80a3830969f7f91777d926 602 PRINTS PR00315 GTP-binding elongation factor signature 71 81 2.3E-14 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AUP74_RS03615 83b963daee80a3830969f7f91777d926 602 PRINTS PR00315 GTP-binding elongation factor signature 7 20 2.3E-14 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AUP74_RS03615 83b963daee80a3830969f7f91777d926 602 PRINTS PR00315 GTP-binding elongation factor signature 51 59 2.3E-14 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AUP74_RS03615 83b963daee80a3830969f7f91777d926 602 PRINTS PR00315 GTP-binding elongation factor signature 123 132 2.3E-14 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AUP74_RS03615 83b963daee80a3830969f7f91777d926 602 PRINTS PR00315 GTP-binding elongation factor signature 87 98 2.3E-14 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AUP74_RS03615 83b963daee80a3830969f7f91777d926 602 Pfam PF03144 Elongation factor Tu domain 2 219 289 1.0E-9 T 11-11-2016 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AUP74_RS03615 83b963daee80a3830969f7f91777d926 602 SUPERFAMILY SSF54980 302 387 2.55E-15 T 11-11-2016 IPR009022 Elongation factor G, III-V domain AUP74_RS03615 83b963daee80a3830969f7f91777d926 602 SUPERFAMILY SSF54980 398 512 1.25E-28 T 11-11-2016 IPR009022 Elongation factor G, III-V domain AUP74_RS03615 83b963daee80a3830969f7f91777d926 602 Gene3D G3DSA:3.40.50.300 3 205 3.1E-66 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03615 83b963daee80a3830969f7f91777d926 602 Gene3D G3DSA:2.40.30.10 206 303 1.9E-29 T 11-11-2016 AUP74_RS03615 83b963daee80a3830969f7f91777d926 602 Gene3D G3DSA:3.30.70.870 304 399 1.3E-38 T 11-11-2016 AUP74_RS03615 83b963daee80a3830969f7f91777d926 602 Pfam PF00009 Elongation factor Tu GTP binding domain 4 194 5.7E-57 T 11-11-2016 AUP74_RS03615 83b963daee80a3830969f7f91777d926 602 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 5 599 3.2E-289 T 11-11-2016 IPR006298 GTP-binding protein TypA GO:0005525 AUP74_RS03615 83b963daee80a3830969f7f91777d926 602 Gene3D G3DSA:2.40.50.250 483 577 3.5E-39 T 11-11-2016 AUP74_RS15740 ed482640cc9e82be95c706625491a1d0 355 Hamap MF_01805 Segregation and condensation protein A [scpA]. 76 307 21.929 T 11-11-2016 IPR003768 Segregation and condensation protein A AUP74_RS15740 ed482640cc9e82be95c706625491a1d0 355 Pfam PF02616 Segregation and condensation protein ScpA 93 303 1.7E-28 T 11-11-2016 IPR003768 Segregation and condensation protein A AUP74_RS09125 8515265529bf42b5ed705c21a84cc4c4 619 Pfam PF00012 Hsp70 protein 21 601 2.5E-186 T 11-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AUP74_RS09125 8515265529bf42b5ed705c21a84cc4c4 619 Gene3D G3DSA:3.30.420.40 19 87 6.3E-53 T 11-11-2016 AUP74_RS09125 8515265529bf42b5ed705c21a84cc4c4 619 Gene3D G3DSA:3.30.420.40 129 206 6.3E-53 T 11-11-2016 AUP74_RS09125 8515265529bf42b5ed705c21a84cc4c4 619 PRINTS PR00301 70kDa heat shock protein signature 329 345 3.9E-56 T 11-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AUP74_RS09125 8515265529bf42b5ed705c21a84cc4c4 619 PRINTS PR00301 70kDa heat shock protein signature 211 221 3.9E-56 T 11-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AUP74_RS09125 8515265529bf42b5ed705c21a84cc4c4 619 PRINTS PR00301 70kDa heat shock protein signature 385 404 3.9E-56 T 11-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AUP74_RS09125 8515265529bf42b5ed705c21a84cc4c4 619 PRINTS PR00301 70kDa heat shock protein signature 48 60 3.9E-56 T 11-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AUP74_RS09125 8515265529bf42b5ed705c21a84cc4c4 619 PRINTS PR00301 70kDa heat shock protein signature 152 172 3.9E-56 T 11-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AUP74_RS09125 8515265529bf42b5ed705c21a84cc4c4 619 PRINTS PR00301 70kDa heat shock protein signature 360 380 3.9E-56 T 11-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AUP74_RS09125 8515265529bf42b5ed705c21a84cc4c4 619 PRINTS PR00301 70kDa heat shock protein signature 466 482 3.9E-56 T 11-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AUP74_RS09125 8515265529bf42b5ed705c21a84cc4c4 619 PRINTS PR00301 70kDa heat shock protein signature 20 33 3.9E-56 T 11-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AUP74_RS09125 8515265529bf42b5ed705c21a84cc4c4 619 TIGRFAM TIGR01991 HscA: Fe-S protein assembly chaperone HscA 21 616 3.2E-267 T 11-11-2016 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 AUP74_RS09125 8515265529bf42b5ed705c21a84cc4c4 619 SUPERFAMILY SSF53067 200 377 2.53E-48 T 11-11-2016 AUP74_RS09125 8515265529bf42b5ed705c21a84cc4c4 619 Gene3D G3DSA:3.30.420.40 207 358 3.9E-31 T 11-11-2016 AUP74_RS09125 8515265529bf42b5ed705c21a84cc4c4 619 Hamap MF_00679 Chaperone protein HscA [hscA]. 1 617 43.8 T 11-11-2016 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 AUP74_RS09125 8515265529bf42b5ed705c21a84cc4c4 619 SUPERFAMILY SSF53067 20 197 5.18E-49 T 11-11-2016 AUP74_RS09125 8515265529bf42b5ed705c21a84cc4c4 619 Gene3D G3DSA:3.30.30.30 88 128 2.7E-7 T 11-11-2016 AUP74_RS09125 8515265529bf42b5ed705c21a84cc4c4 619 SUPERFAMILY SSF100920 384 537 7.06E-51 T 11-11-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 AUP74_RS09125 8515265529bf42b5ed705c21a84cc4c4 619 Gene3D G3DSA:2.60.34.10 387 528 1.7E-55 T 11-11-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 AUP74_RS09125 8515265529bf42b5ed705c21a84cc4c4 619 Gene3D G3DSA:1.20.1270.10 529 616 1.4E-28 T 11-11-2016 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 AUP74_RS09125 8515265529bf42b5ed705c21a84cc4c4 619 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 24 31 - T 11-11-2016 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 AUP74_RS09125 8515265529bf42b5ed705c21a84cc4c4 619 SUPERFAMILY SSF100934 504 616 1.41E-32 T 11-11-2016 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 AUP74_RS09125 8515265529bf42b5ed705c21a84cc4c4 619 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 205 218 - T 11-11-2016 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 AUP74_RS05320 ad3cff303a9b5f4265b619d48a66414d 564 SUPERFAMILY SSF56300 350 378 3.52E-33 T 11-11-2016 IPR029052 Metallo-dependent phosphatase-like AUP74_RS05320 ad3cff303a9b5f4265b619d48a66414d 564 SUPERFAMILY SSF56300 428 543 3.52E-33 T 11-11-2016 IPR029052 Metallo-dependent phosphatase-like AUP74_RS05320 ad3cff303a9b5f4265b619d48a66414d 564 SUPERFAMILY SSF56300 141 317 3.52E-33 T 11-11-2016 IPR029052 Metallo-dependent phosphatase-like AUP74_RS05320 ad3cff303a9b5f4265b619d48a66414d 564 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 42 134 1.0E-32 T 11-11-2016 IPR032093 Phospholipase D, N-terminal AUP74_RS05320 ad3cff303a9b5f4265b619d48a66414d 564 Gene3D G3DSA:2.60.40.380 50 137 7.1E-4 T 11-11-2016 IPR015914 Purple acid phosphatase, N-terminal GO:0003993|GO:0046872 AUP74_RS05320 ad3cff303a9b5f4265b619d48a66414d 564 Pfam PF09423 PhoD-like phosphatase 145 540 1.3E-124 T 11-11-2016 IPR018946 Alkaline phosphatase D-related AUP74_RS05320 ad3cff303a9b5f4265b619d48a66414d 564 Gene3D G3DSA:3.60.21.10 142 367 5.0E-10 T 11-11-2016 IPR029052 Metallo-dependent phosphatase-like AUP74_RS13955 d14ee50aac9b17cd727e105868cc4f41 196 Hamap MF_01924 D-alanyl-D-alanine dipeptidase [ddpX]. 2 194 28.899 T 11-11-2016 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 AUP74_RS13955 d14ee50aac9b17cd727e105868cc4f41 196 Gene3D G3DSA:3.30.1380.10 6 195 6.3E-68 T 11-11-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 AUP74_RS13955 d14ee50aac9b17cd727e105868cc4f41 196 PIRSF PIRSF026671 1 196 3.4E-62 T 11-11-2016 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 AUP74_RS13955 d14ee50aac9b17cd727e105868cc4f41 196 Pfam PF01427 D-ala-D-ala dipeptidase 6 195 7.9E-47 T 11-11-2016 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 AUP74_RS13955 d14ee50aac9b17cd727e105868cc4f41 196 SUPERFAMILY SSF55166 7 195 3.41E-61 T 11-11-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 AUP74_RS11470 a4057714b1431d3fbb2dad24f511e375 1040 SUPERFAMILY SSF82693 55 145 1.39E-20 T 11-11-2016 AUP74_RS11470 a4057714b1431d3fbb2dad24f511e375 1040 Gene3D G3DSA:1.10.3850.10 807 1020 3.5E-56 T 11-11-2016 AUP74_RS11470 a4057714b1431d3fbb2dad24f511e375 1040 Gene3D G3DSA:3.30.2090.10 713 799 8.6E-16 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS11470 a4057714b1431d3fbb2dad24f511e375 1040 Gene3D G3DSA:3.30.2090.10 197 276 8.8E-11 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS11470 a4057714b1431d3fbb2dad24f511e375 1040 Gene3D G3DSA:1.20.1640.10 309 501 6.2E-53 T 11-11-2016 AUP74_RS11470 a4057714b1431d3fbb2dad24f511e375 1040 SUPERFAMILY SSF82693 565 663 6.54E-13 T 11-11-2016 AUP74_RS11470 a4057714b1431d3fbb2dad24f511e375 1040 SUPERFAMILY SSF82714 198 276 4.32E-11 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS11470 a4057714b1431d3fbb2dad24f511e375 1040 SUPERFAMILY SSF82714 714 798 2.62E-15 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS11470 a4057714b1431d3fbb2dad24f511e375 1040 Pfam PF00873 AcrB/AcrD/AcrF family 19 1018 1.7E-252 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS11470 a4057714b1431d3fbb2dad24f511e375 1040 SUPERFAMILY SSF82693 152 196 1.67E-14 T 11-11-2016 AUP74_RS11470 a4057714b1431d3fbb2dad24f511e375 1040 SUPERFAMILY SSF82693 278 331 1.67E-14 T 11-11-2016 AUP74_RS11470 a4057714b1431d3fbb2dad24f511e375 1040 Gene3D G3DSA:3.30.70.1430 55 153 4.2E-25 T 11-11-2016 AUP74_RS11470 a4057714b1431d3fbb2dad24f511e375 1040 SUPERFAMILY SSF82866 301 498 1.31E-41 T 11-11-2016 AUP74_RS11470 a4057714b1431d3fbb2dad24f511e375 1040 PRINTS PR00702 Acriflavin resistance protein family signature 366 387 2.0E-62 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS11470 a4057714b1431d3fbb2dad24f511e375 1040 PRINTS PR00702 Acriflavin resistance protein family signature 472 495 2.0E-62 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS11470 a4057714b1431d3fbb2dad24f511e375 1040 PRINTS PR00702 Acriflavin resistance protein family signature 394 418 2.0E-62 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS11470 a4057714b1431d3fbb2dad24f511e375 1040 PRINTS PR00702 Acriflavin resistance protein family signature 53 71 2.0E-62 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS11470 a4057714b1431d3fbb2dad24f511e375 1040 PRINTS PR00702 Acriflavin resistance protein family signature 447 470 2.0E-62 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS11470 a4057714b1431d3fbb2dad24f511e375 1040 PRINTS PR00702 Acriflavin resistance protein family signature 339 362 2.0E-62 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS11470 a4057714b1431d3fbb2dad24f511e375 1040 PRINTS PR00702 Acriflavin resistance protein family signature 552 569 2.0E-62 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS11470 a4057714b1431d3fbb2dad24f511e375 1040 PRINTS PR00702 Acriflavin resistance protein family signature 618 632 2.0E-62 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS11470 a4057714b1431d3fbb2dad24f511e375 1040 PRINTS PR00702 Acriflavin resistance protein family signature 25 49 2.0E-62 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS11470 a4057714b1431d3fbb2dad24f511e375 1040 Gene3D G3DSA:3.30.70.1320 280 308 5.8E-11 T 11-11-2016 AUP74_RS11470 a4057714b1431d3fbb2dad24f511e375 1040 Gene3D G3DSA:3.30.70.1320 154 193 5.8E-11 T 11-11-2016 AUP74_RS11470 a4057714b1431d3fbb2dad24f511e375 1040 Gene3D G3DSA:3.30.70.1430 568 661 7.7E-7 T 11-11-2016 AUP74_RS11470 a4057714b1431d3fbb2dad24f511e375 1040 SUPERFAMILY SSF82866 805 1023 1.27E-43 T 11-11-2016 AUP74_RS11810 69ecdbf3acd54ff8b7280279dd0781fa 254 Gene3D G3DSA:3.60.40.10 24 253 4.7E-59 T 11-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 AUP74_RS11810 69ecdbf3acd54ff8b7280279dd0781fa 254 SMART SM00331 25 254 1.3E-21 T 11-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 AUP74_RS11810 69ecdbf3acd54ff8b7280279dd0781fa 254 SUPERFAMILY SSF81606 24 252 1.2E-55 T 11-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 AUP74_RS11810 69ecdbf3acd54ff8b7280279dd0781fa 254 Pfam PF13672 Protein phosphatase 2C 33 216 2.3E-13 T 11-11-2016 AUP74_RS11810 69ecdbf3acd54ff8b7280279dd0781fa 254 SMART SM00332 20 252 7.5E-20 T 11-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 AUP74_RS08030 dbdc5b94093378270ed54722ec929805 253 PIRSF PIRSF006648 7 250 6.5E-30 T 11-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 AUP74_RS08030 dbdc5b94093378270ed54722ec929805 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 55 77 4.3E-15 T 11-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 AUP74_RS08030 dbdc5b94093378270ed54722ec929805 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 193 212 4.3E-15 T 11-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 AUP74_RS08030 dbdc5b94093378270ed54722ec929805 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 136 160 4.3E-15 T 11-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 AUP74_RS08030 dbdc5b94093378270ed54722ec929805 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 173 192 4.3E-15 T 11-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 AUP74_RS08030 dbdc5b94093378270ed54722ec929805 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 99 124 4.3E-15 T 11-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 AUP74_RS08030 dbdc5b94093378270ed54722ec929805 253 Pfam PF01061 ABC-2 type transporter 6 216 4.9E-36 T 11-11-2016 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AUP74_RS13365 8b38a65777ec41843f35fd519056507f 537 Pfam PF00561 alpha/beta hydrolase fold 117 252 2.2E-17 T 11-11-2016 IPR000073 Alpha/beta hydrolase fold-1 AUP74_RS13365 8b38a65777ec41843f35fd519056507f 537 Pfam PF08386 TAP-like protein 409 498 3.7E-8 T 11-11-2016 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal AUP74_RS13365 8b38a65777ec41843f35fd519056507f 537 SUPERFAMILY SSF53474 74 140 3.44E-27 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS13365 8b38a65777ec41843f35fd519056507f 537 SUPERFAMILY SSF53474 429 490 3.44E-27 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS13365 8b38a65777ec41843f35fd519056507f 537 SUPERFAMILY SSF53474 312 351 3.44E-27 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS13365 8b38a65777ec41843f35fd519056507f 537 SUPERFAMILY SSF53474 183 250 3.44E-27 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS13365 8b38a65777ec41843f35fd519056507f 537 Gene3D G3DSA:3.40.50.1820 373 492 6.5E-42 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS13365 8b38a65777ec41843f35fd519056507f 537 Gene3D G3DSA:3.40.50.1820 189 303 6.5E-42 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS13365 8b38a65777ec41843f35fd519056507f 537 Gene3D G3DSA:3.40.50.1820 56 147 6.5E-42 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS03795 5bb488cb635ee014366a60d74851a46b 87 Pfam PF07615 YKOF-related Family 5 60 3.1E-5 T 11-11-2016 IPR011522 Thiamin/hydroxymethyl pyrimidine-binding YkoF, putative AUP74_RS03795 5bb488cb635ee014366a60d74851a46b 87 Gene3D G3DSA:3.30.70.930 2 77 3.0E-11 T 11-11-2016 IPR029756 MTH1187/YkoF-like AUP74_RS03795 5bb488cb635ee014366a60d74851a46b 87 SUPERFAMILY SSF89957 1 79 2.22E-21 T 11-11-2016 IPR029756 MTH1187/YkoF-like AUP74_RS13605 d7e392799e8ef73a22196e441aa1db4d 370 Gene3D G3DSA:1.20.1510.10 6 232 3.0E-23 T 11-11-2016 IPR027469 Cation efflux protein transmembrane domain AUP74_RS13605 d7e392799e8ef73a22196e441aa1db4d 370 SUPERFAMILY SSF161111 5 232 1.83E-27 T 11-11-2016 AUP74_RS13605 d7e392799e8ef73a22196e441aa1db4d 370 Pfam PF01545 Cation efflux family 10 232 2.5E-22 T 11-11-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AUP74_RS13605 d7e392799e8ef73a22196e441aa1db4d 370 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 6 311 1.7E-24 T 11-11-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AUP74_RS03885 c8032bde7986944f2a889f467d3ad37d 228 Pfam PF04172 LrgB-like family 16 226 2.7E-62 T 11-11-2016 IPR007300 CidB/LrgB family AUP74_RS03820 216eecacc794197f96fa8e568364e42f 441 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 3 441 42.94 T 11-11-2016 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 AUP74_RS03820 216eecacc794197f96fa8e568364e42f 441 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 333 402 4.1E-5 T 11-11-2016 IPR019489 Clp ATPase, C-terminal AUP74_RS03820 216eecacc794197f96fa8e568364e42f 441 Gene3D G3DSA:1.10.8.60 332 441 5.4E-33 T 11-11-2016 AUP74_RS03820 216eecacc794197f96fa8e568364e42f 441 Gene3D G3DSA:3.40.50.300 5 112 1.0E-54 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03820 216eecacc794197f96fa8e568364e42f 441 Gene3D G3DSA:3.40.50.300 243 329 1.0E-54 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03820 216eecacc794197f96fa8e568364e42f 441 Pfam PF07724 AAA domain (Cdc48 subfamily) 187 327 3.3E-41 T 11-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 AUP74_RS03820 216eecacc794197f96fa8e568364e42f 441 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 55 106 1.1E-6 T 11-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 AUP74_RS03820 216eecacc794197f96fa8e568364e42f 441 Gene3D G3DSA:1.10.8.10 211 241 8.4E-28 T 11-11-2016 AUP74_RS03820 216eecacc794197f96fa8e568364e42f 441 Gene3D G3DSA:1.10.8.10 113 175 8.4E-28 T 11-11-2016 AUP74_RS03820 216eecacc794197f96fa8e568364e42f 441 SMART SM00382 51 330 1.1E-11 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS03820 216eecacc794197f96fa8e568364e42f 441 SUPERFAMILY SSF52540 5 439 2.62E-87 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03820 216eecacc794197f96fa8e568364e42f 441 SMART SM01086 333 432 2.5E-16 T 11-11-2016 IPR019489 Clp ATPase, C-terminal AUP74_RS03820 216eecacc794197f96fa8e568364e42f 441 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 6 441 5.8E-209 T 11-11-2016 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 AUP74_RS04400 4b001e15bb02f9280fe13c7b1915b7e7 514 Gene3D G3DSA:3.40.50.300 95 383 1.1E-113 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04400 4b001e15bb02f9280fe13c7b1915b7e7 514 SUPERFAMILY SSF52540 97 382 1.25E-93 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04400 4b001e15bb02f9280fe13c7b1915b7e7 514 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 367 376 - T 11-11-2016 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AUP74_RS04400 4b001e15bb02f9280fe13c7b1915b7e7 514 SUPERFAMILY SSF47917 384 511 3.4E-47 T 11-11-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AUP74_RS04400 4b001e15bb02f9280fe13c7b1915b7e7 514 Gene3D G3DSA:2.40.30.20 3 94 8.6E-34 T 11-11-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 AUP74_RS04400 4b001e15bb02f9280fe13c7b1915b7e7 514 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 4 511 3.0E-252 T 11-11-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 AUP74_RS04400 4b001e15bb02f9280fe13c7b1915b7e7 514 SUPERFAMILY SSF50615 11 95 8.83E-29 T 11-11-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AUP74_RS04400 4b001e15bb02f9280fe13c7b1915b7e7 514 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 27 93 1.4E-15 T 11-11-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AUP74_RS04400 4b001e15bb02f9280fe13c7b1915b7e7 514 PIRSF PIRSF039088 2 513 4.4E-234 T 11-11-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 AUP74_RS04400 4b001e15bb02f9280fe13c7b1915b7e7 514 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 383 508 9.5E-46 T 11-11-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AUP74_RS04400 4b001e15bb02f9280fe13c7b1915b7e7 514 Gene3D G3DSA:1.20.150.20 384 511 4.5E-49 T 11-11-2016 AUP74_RS04400 4b001e15bb02f9280fe13c7b1915b7e7 514 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 2 513 50.014 T 11-11-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 AUP74_RS04400 4b001e15bb02f9280fe13c7b1915b7e7 514 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 150 376 1.5E-74 T 11-11-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AUP74_RS14005 4ce58a3c8633f26a916bfd023aa4214a 733 SUPERFAMILY SSF55486 333 573 5.05E-30 T 11-11-2016 AUP74_RS14005 4ce58a3c8633f26a916bfd023aa4214a 733 Gene3D G3DSA:1.10.390.10 447 571 7.5E-15 T 11-11-2016 AUP74_RS02020 7f078c0e46de1645daf726f100848a55 217 SUPERFAMILY SSF48452 53 184 2.66E-10 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS02020 7f078c0e46de1645daf726f100848a55 217 Gene3D G3DSA:1.25.40.10 96 185 3.3E-10 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS09990 949692493ac941d0c1a6e8ae538f30e0 1052 Pfam PF00873 AcrB/AcrD/AcrF family 2 1032 0.0 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS09990 949692493ac941d0c1a6e8ae538f30e0 1052 Gene3D G3DSA:3.30.2090.10 186 277 7.0E-28 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS09990 949692493ac941d0c1a6e8ae538f30e0 1052 SUPERFAMILY SSF82693 279 335 5.76E-23 T 11-11-2016 AUP74_RS09990 949692493ac941d0c1a6e8ae538f30e0 1052 SUPERFAMILY SSF82693 152 186 5.76E-23 T 11-11-2016 AUP74_RS09990 949692493ac941d0c1a6e8ae538f30e0 1052 SUPERFAMILY SSF82866 812 1035 5.75E-40 T 11-11-2016 AUP74_RS09990 949692493ac941d0c1a6e8ae538f30e0 1052 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 3 1038 0.0 T 11-11-2016 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 AUP74_RS09990 949692493ac941d0c1a6e8ae538f30e0 1052 SUPERFAMILY SSF82693 572 678 2.62E-27 T 11-11-2016 AUP74_RS09990 949692493ac941d0c1a6e8ae538f30e0 1052 SUPERFAMILY SSF82714 187 276 7.98E-23 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS09990 949692493ac941d0c1a6e8ae538f30e0 1052 Gene3D G3DSA:3.30.70.1430 39 140 6.6E-31 T 11-11-2016 AUP74_RS09990 949692493ac941d0c1a6e8ae538f30e0 1052 SUPERFAMILY SSF82693 39 132 7.32E-26 T 11-11-2016 AUP74_RS09990 949692493ac941d0c1a6e8ae538f30e0 1052 Gene3D G3DSA:1.20.1640.10 298 509 6.1E-60 T 11-11-2016 AUP74_RS09990 949692493ac941d0c1a6e8ae538f30e0 1052 Gene3D G3DSA:3.30.70.1430 574 678 2.3E-27 T 11-11-2016 AUP74_RS09990 949692493ac941d0c1a6e8ae538f30e0 1052 PRINTS PR00702 Acriflavin resistance protein family signature 474 497 4.6E-94 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS09990 949692493ac941d0c1a6e8ae538f30e0 1052 PRINTS PR00702 Acriflavin resistance protein family signature 341 364 4.6E-94 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS09990 949692493ac941d0c1a6e8ae538f30e0 1052 PRINTS PR00702 Acriflavin resistance protein family signature 396 420 4.6E-94 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS09990 949692493ac941d0c1a6e8ae538f30e0 1052 PRINTS PR00702 Acriflavin resistance protein family signature 628 642 4.6E-94 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS09990 949692493ac941d0c1a6e8ae538f30e0 1052 PRINTS PR00702 Acriflavin resistance protein family signature 9 33 4.6E-94 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS09990 949692493ac941d0c1a6e8ae538f30e0 1052 PRINTS PR00702 Acriflavin resistance protein family signature 368 389 4.6E-94 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS09990 949692493ac941d0c1a6e8ae538f30e0 1052 PRINTS PR00702 Acriflavin resistance protein family signature 559 576 4.6E-94 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS09990 949692493ac941d0c1a6e8ae538f30e0 1052 PRINTS PR00702 Acriflavin resistance protein family signature 37 55 4.6E-94 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS09990 949692493ac941d0c1a6e8ae538f30e0 1052 PRINTS PR00702 Acriflavin resistance protein family signature 449 472 4.6E-94 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS09990 949692493ac941d0c1a6e8ae538f30e0 1052 Gene3D G3DSA:1.10.3850.10 820 1034 4.1E-54 T 11-11-2016 AUP74_RS09990 949692493ac941d0c1a6e8ae538f30e0 1052 SUPERFAMILY SSF82714 729 813 2.35E-16 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS09990 949692493ac941d0c1a6e8ae538f30e0 1052 SUPERFAMILY SSF82866 301 502 1.27E-51 T 11-11-2016 AUP74_RS09990 949692493ac941d0c1a6e8ae538f30e0 1052 Gene3D G3DSA:3.30.2090.10 728 812 8.9E-18 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS10565 3524de23bc9480657e0c9e2756daa908 404 SUPERFAMILY SSF53383 4 402 5.64E-91 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase AUP74_RS10565 3524de23bc9480657e0c9e2756daa908 404 Gene3D G3DSA:3.40.640.10 51 243 8.1E-57 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AUP74_RS10565 3524de23bc9480657e0c9e2756daa908 404 Pfam PF00155 Aminotransferase class I and II 38 394 1.1E-44 T 11-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AUP74_RS10565 3524de23bc9480657e0c9e2756daa908 404 Gene3D G3DSA:3.90.1150.10 244 402 1.2E-41 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS06990 83db804e9b4afdd02fc802295ccf28b2 388 SUPERFAMILY SSF103473 1 380 1.57E-63 T 11-11-2016 IPR020846 Major facilitator superfamily domain AUP74_RS06990 83db804e9b4afdd02fc802295ccf28b2 388 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 136 161 - T 11-11-2016 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 AUP74_RS06990 83db804e9b4afdd02fc802295ccf28b2 388 Gene3D G3DSA:1.20.1250.20 6 186 1.8E-34 T 11-11-2016 AUP74_RS06990 83db804e9b4afdd02fc802295ccf28b2 388 Gene3D G3DSA:1.20.1250.20 205 379 1.1E-17 T 11-11-2016 AUP74_RS06990 83db804e9b4afdd02fc802295ccf28b2 388 Pfam PF07690 Major Facilitator Superfamily 13 247 3.0E-31 T 11-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AUP74_RS06990 83db804e9b4afdd02fc802295ccf28b2 388 ProSitePatterns PS00216 Sugar transport proteins signature 1. 63 79 - T 11-11-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AUP74_RS13405 3241dc9bfd685fae1889dca09e982b54 258 Hamap MF_02057 tRNA 5-carboxymethoxyuridine methyltransferase [cmoM]. 2 258 37.894 T 11-11-2016 IPR033664 tRNA 5-carboxymethoxyuridine methyltransferase GO:0008168 AUP74_RS13405 3241dc9bfd685fae1889dca09e982b54 258 SUPERFAMILY SSF53335 4 253 3.53E-36 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS13405 3241dc9bfd685fae1889dca09e982b54 258 Pfam PF13489 Methyltransferase domain 30 208 2.4E-16 T 11-11-2016 AUP74_RS13405 3241dc9bfd685fae1889dca09e982b54 258 Gene3D G3DSA:3.40.50.150 32 223 3.7E-32 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS05260 410c4c5b4c5105a8b521644278e23f6f 228 SMART SM00382 34 217 2.7E-12 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS05260 410c4c5b4c5105a8b521644278e23f6f 228 SUPERFAMILY SSF52540 5 224 2.13E-58 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05260 410c4c5b4c5105a8b521644278e23f6f 228 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AUP74_RS05260 410c4c5b4c5105a8b521644278e23f6f 228 Pfam PF00005 ABC transporter 25 169 9.3E-31 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AUP74_RS05260 410c4c5b4c5105a8b521644278e23f6f 228 Gene3D G3DSA:3.40.50.300 4 219 2.2E-59 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS07225 b126484d978a0ff06a434ed3392f7d8d 341 SUPERFAMILY SSF51735 1 183 7.91E-77 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS07225 b126484d978a0ff06a434ed3392f7d8d 341 Hamap MF_00435 Ketol-acid reductoisomerase [ilvC]. 1 329 46.436 T 11-11-2016 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AUP74_RS07225 b126484d978a0ff06a434ed3392f7d8d 341 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 14 328 8.9E-140 T 11-11-2016 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AUP74_RS07225 b126484d978a0ff06a434ed3392f7d8d 341 Gene3D G3DSA:1.10.1040.10 39 326 4.8E-118 T 11-11-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AUP74_RS07225 b126484d978a0ff06a434ed3392f7d8d 341 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 14 178 5.6E-78 T 11-11-2016 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AUP74_RS07225 b126484d978a0ff06a434ed3392f7d8d 341 SUPERFAMILY SSF48179 184 335 2.38E-71 T 11-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AUP74_RS07225 b126484d978a0ff06a434ed3392f7d8d 341 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 184 327 4.3E-66 T 11-11-2016 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AUP74_RS07225 b126484d978a0ff06a434ed3392f7d8d 341 Gene3D G3DSA:3.50.50.60 2 38 2.1E-4 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS15590 221bc1eea62da210b0f59ef22d0dd2dc 385 Gene3D G3DSA:3.40.50.2000 163 354 6.1E-5 T 11-11-2016 AUP74_RS15590 221bc1eea62da210b0f59ef22d0dd2dc 385 Pfam PF02684 Lipid-A-disaccharide synthetase 10 376 2.3E-107 T 11-11-2016 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 AUP74_RS15590 221bc1eea62da210b0f59ef22d0dd2dc 385 SUPERFAMILY SSF53756 9 381 1.48E-36 T 11-11-2016 AUP74_RS15590 221bc1eea62da210b0f59ef22d0dd2dc 385 Hamap MF_00392 Lipid-A-disaccharide synthase [lpxB]. 7 382 39.987 T 11-11-2016 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 AUP74_RS15590 221bc1eea62da210b0f59ef22d0dd2dc 385 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 6 379 7.8E-120 T 11-11-2016 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 AUP74_RS05305 4ca30e03ce53e05ccf9737c7f736ce87 985 Gene3D G3DSA:3.30.830.10 295 471 4.8E-16 T 11-11-2016 IPR011237 Peptidase M16 domain GO:0046872 AUP74_RS05305 4ca30e03ce53e05ccf9737c7f736ce87 985 SUPERFAMILY SSF63411 752 954 9.17E-33 T 11-11-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AUP74_RS05305 4ca30e03ce53e05ccf9737c7f736ce87 985 Gene3D G3DSA:3.30.830.10 760 942 1.1E-21 T 11-11-2016 IPR011237 Peptidase M16 domain GO:0046872 AUP74_RS05305 4ca30e03ce53e05ccf9737c7f736ce87 985 SUPERFAMILY SSF63411 62 270 4.22E-54 T 11-11-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AUP74_RS05305 4ca30e03ce53e05ccf9737c7f736ce87 985 Pfam PF00675 Insulinase (Peptidase family M16) 74 211 5.6E-18 T 11-11-2016 IPR011765 Peptidase M16, N-terminal AUP74_RS05305 4ca30e03ce53e05ccf9737c7f736ce87 985 Pfam PF00675 Insulinase (Peptidase family M16) 546 675 9.9E-15 T 11-11-2016 IPR011765 Peptidase M16, N-terminal AUP74_RS05305 4ca30e03ce53e05ccf9737c7f736ce87 985 Pfam PF05193 Peptidase M16 inactive domain 232 406 2.2E-24 T 11-11-2016 IPR007863 Peptidase M16, C-terminal AUP74_RS05305 4ca30e03ce53e05ccf9737c7f736ce87 985 Pfam PF05193 Peptidase M16 inactive domain 697 874 3.4E-14 T 11-11-2016 IPR007863 Peptidase M16, C-terminal AUP74_RS05305 4ca30e03ce53e05ccf9737c7f736ce87 985 SUPERFAMILY SSF63411 292 480 6.33E-30 T 11-11-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AUP74_RS05305 4ca30e03ce53e05ccf9737c7f736ce87 985 SUPERFAMILY SSF63411 528 736 1.92E-42 T 11-11-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AUP74_RS05305 4ca30e03ce53e05ccf9737c7f736ce87 985 Gene3D G3DSA:3.30.830.10 529 733 3.9E-39 T 11-11-2016 IPR011237 Peptidase M16 domain GO:0046872 AUP74_RS05305 4ca30e03ce53e05ccf9737c7f736ce87 985 Gene3D G3DSA:3.30.830.10 62 285 7.0E-55 T 11-11-2016 IPR011237 Peptidase M16 domain GO:0046872 AUP74_RS01375 cef3340d1b033723b761f3a75d3d6f28 183 Gene3D G3DSA:1.20.950.20 68 152 3.9E-4 T 11-11-2016 AUP74_RS01375 cef3340d1b033723b761f3a75d3d6f28 183 SUPERFAMILY SSF81342 1 162 6.2E-32 T 11-11-2016 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 AUP74_RS01375 cef3340d1b033723b761f3a75d3d6f28 183 Pfam PF01292 Prokaryotic cytochrome b561 1 160 5.2E-26 T 11-11-2016 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 AUP74_RS16480 4e05480318d58d9a55c6f8a9ade83d4d 209 TIGRFAM TIGR03902 rhom_GG_sort: rhombosortase 34 187 1.4E-35 T 11-11-2016 IPR023826 Rhomboid-like serine protease, proteobacteria AUP74_RS16480 4e05480318d58d9a55c6f8a9ade83d4d 209 SUPERFAMILY SSF144091 25 192 9.94E-17 T 11-11-2016 AUP74_RS16480 4e05480318d58d9a55c6f8a9ade83d4d 209 Gene3D G3DSA:1.20.1540.10 23 189 1.3E-9 T 11-11-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 AUP74_RS16480 4e05480318d58d9a55c6f8a9ade83d4d 209 Pfam PF01694 Rhomboid family 45 190 1.2E-9 T 11-11-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 AUP74_RS13705 712cfebf0a6a03ad7c896d107e12e2e5 1048 TIGRFAM TIGR01238 D1pyr5carbox3: delta-1-pyrroline-5-carboxylate dehydrogenase 528 1026 1.2E-194 T 11-11-2016 IPR005933 Delta-1-pyrroline-5-carboxylate dehydrogenase 3 GO:0003842|GO:0006561|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 AUP74_RS13705 712cfebf0a6a03ad7c896d107e12e2e5 1048 Gene3D G3DSA:3.40.309.10 817 994 1.9E-41 T 11-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 AUP74_RS13705 712cfebf0a6a03ad7c896d107e12e2e5 1048 Gene3D G3DSA:3.40.605.10 569 816 1.3E-73 T 11-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AUP74_RS13705 712cfebf0a6a03ad7c896d107e12e2e5 1048 SUPERFAMILY SSF53720 552 1033 6.41E-129 T 11-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AUP74_RS13705 712cfebf0a6a03ad7c896d107e12e2e5 1048 SUPERFAMILY SSF81935 10 181 3.14E-57 T 11-11-2016 IPR024089 Proline dehydrogenase PutA, domain I/II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 AUP74_RS13705 712cfebf0a6a03ad7c896d107e12e2e5 1048 Pfam PF14850 DNA-binding domain of Proline dehydrogenase 66 179 1.4E-42 T 11-11-2016 IPR024082 Proline dehydrogenase PutA, domain II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 AUP74_RS13705 712cfebf0a6a03ad7c896d107e12e2e5 1048 Gene3D G3DSA:1.10.2060.10 59 180 3.3E-47 T 11-11-2016 IPR024082 Proline dehydrogenase PutA, domain II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 AUP74_RS13705 712cfebf0a6a03ad7c896d107e12e2e5 1048 Pfam PF01619 Proline dehydrogenase 195 483 1.2E-95 T 11-11-2016 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 AUP74_RS13705 712cfebf0a6a03ad7c896d107e12e2e5 1048 PIRSF PIRSF000197 1 1046 0.0 T 11-11-2016 IPR025703 Bifunctional protein PutA GO:0003700|GO:0003842|GO:0004657|GO:0006355|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 AUP74_RS13705 712cfebf0a6a03ad7c896d107e12e2e5 1048 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 830 841 - T 11-11-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 AUP74_RS13705 712cfebf0a6a03ad7c896d107e12e2e5 1048 SUPERFAMILY SSF51730 182 520 1.88E-116 T 11-11-2016 IPR029041 FAD-linked oxidoreductase-like AUP74_RS13705 712cfebf0a6a03ad7c896d107e12e2e5 1048 Gene3D G3DSA:3.20.20.220 182 519 2.2E-107 T 11-11-2016 IPR029041 FAD-linked oxidoreductase-like AUP74_RS13705 712cfebf0a6a03ad7c896d107e12e2e5 1048 Pfam PF00171 Aldehyde dehydrogenase family 572 1029 7.7E-119 T 11-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 AUP74_RS12735 8104085252fd90d660cd16559c78b5ee 303 Gene3D G3DSA:2.60.120.10 26 261 1.8E-66 T 11-11-2016 IPR014710 RmlC-like jelly roll fold AUP74_RS12735 8104085252fd90d660cd16559c78b5ee 303 SUPERFAMILY SSF51182 25 302 5.34E-77 T 11-11-2016 IPR011051 RmlC-like cupin domain AUP74_RS12735 8104085252fd90d660cd16559c78b5ee 303 Pfam PF05726 Pirin C-terminal cupin domain 193 290 3.0E-20 T 11-11-2016 IPR008778 Pirin, C-terminal domain AUP74_RS12735 8104085252fd90d660cd16559c78b5ee 303 Pfam PF02678 Pirin 35 140 2.4E-32 T 11-11-2016 IPR003829 Pirin, N-terminal domain AUP74_RS12735 8104085252fd90d660cd16559c78b5ee 303 PIRSF PIRSF006232 18 298 4.3E-86 T 11-11-2016 IPR012093 Pirin AUP74_RS04510 684d35ad975a9a64972384aeb138a6b8 456 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 21 451 1.5E-105 T 11-11-2016 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 AUP74_RS04510 684d35ad975a9a64972384aeb138a6b8 456 Pfam PF00919 Uncharacterized protein family UPF0004 21 112 2.2E-21 T 11-11-2016 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 AUP74_RS04510 684d35ad975a9a64972384aeb138a6b8 456 SMART SM00729 153 378 6.3E-50 T 11-11-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 AUP74_RS04510 684d35ad975a9a64972384aeb138a6b8 456 Pfam PF04055 Radical SAM superfamily 159 336 3.8E-26 T 11-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 AUP74_RS04510 684d35ad975a9a64972384aeb138a6b8 456 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 21 450 3.0E-178 T 11-11-2016 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 AUP74_RS04510 684d35ad975a9a64972384aeb138a6b8 456 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 157 177 - T 11-11-2016 IPR020612 Methylthiotransferase, conserved site GO:0051539 AUP74_RS04510 684d35ad975a9a64972384aeb138a6b8 456 SUPERFAMILY SSF102114 131 383 3.27E-51 T 11-11-2016 AUP74_RS04510 684d35ad975a9a64972384aeb138a6b8 456 Gene3D G3DSA:3.80.30.20 151 390 5.5E-70 T 11-11-2016 IPR023404 Radical SAM, alpha/beta horseshoe AUP74_RS04510 684d35ad975a9a64972384aeb138a6b8 456 Gene3D G3DSA:2.40.50.140 393 454 4.2E-27 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS04510 684d35ad975a9a64972384aeb138a6b8 456 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 20 453 61.692 T 11-11-2016 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 AUP74_RS00790 b2ce4f0b808345111847764f42967ea0 233 Gene3D G3DSA:3.40.50.300 1 220 4.9E-69 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS00790 b2ce4f0b808345111847764f42967ea0 233 SMART SM00382 30 219 1.1E-15 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS00790 b2ce4f0b808345111847764f42967ea0 233 Pfam PF00005 ABC transporter 21 169 9.8E-32 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AUP74_RS00790 b2ce4f0b808345111847764f42967ea0 233 SUPERFAMILY SSF52540 1 223 5.72E-72 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS00790 b2ce4f0b808345111847764f42967ea0 233 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AUP74_RS00190 2542d30a51723381b747fa731ad6af26 309 SUPERFAMILY SSF53271 65 300 4.4E-62 T 11-11-2016 IPR029057 Phosphoribosyltransferase-like AUP74_RS00190 2542d30a51723381b747fa731ad6af26 309 Pfam PF14572 Phosphoribosyl synthetase-associated domain 199 309 8.4E-30 T 11-11-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AUP74_RS00190 2542d30a51723381b747fa731ad6af26 309 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 1 309 47.166 T 11-11-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AUP74_RS00190 2542d30a51723381b747fa731ad6af26 309 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 125 140 - T 11-11-2016 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 AUP74_RS00190 2542d30a51723381b747fa731ad6af26 309 Gene3D G3DSA:3.40.50.2020 1 156 3.7E-70 T 11-11-2016 IPR029057 Phosphoribosyltransferase-like AUP74_RS00190 2542d30a51723381b747fa731ad6af26 309 SMART SM01400 1 117 3.8E-70 T 11-11-2016 AUP74_RS00190 2542d30a51723381b747fa731ad6af26 309 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 2 117 6.5E-46 T 11-11-2016 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AUP74_RS00190 2542d30a51723381b747fa731ad6af26 309 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 1 309 2.5E-120 T 11-11-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AUP74_RS00190 2542d30a51723381b747fa731ad6af26 309 Gene3D G3DSA:3.40.50.2020 157 283 1.8E-54 T 11-11-2016 IPR029057 Phosphoribosyltransferase-like AUP74_RS14110 7912d7961686f706509f3028f0a2313d 1016 SUPERFAMILY SSF82714 703 774 1.44E-9 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS14110 7912d7961686f706509f3028f0a2313d 1016 SUPERFAMILY SSF82693 555 620 3.56E-5 T 11-11-2016 AUP74_RS14110 7912d7961686f706509f3028f0a2313d 1016 SUPERFAMILY SSF82693 138 182 2.25E-18 T 11-11-2016 AUP74_RS14110 7912d7961686f706509f3028f0a2313d 1016 SUPERFAMILY SSF82693 270 325 2.25E-18 T 11-11-2016 AUP74_RS14110 7912d7961686f706509f3028f0a2313d 1016 SUPERFAMILY SSF82693 40 134 1.41E-18 T 11-11-2016 AUP74_RS14110 7912d7961686f706509f3028f0a2313d 1016 SUPERFAMILY SSF82866 294 489 1.1E-35 T 11-11-2016 AUP74_RS14110 7912d7961686f706509f3028f0a2313d 1016 Gene3D G3DSA:3.30.2090.10 187 268 1.1E-9 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS14110 7912d7961686f706509f3028f0a2313d 1016 Gene3D G3DSA:3.30.2090.10 703 773 2.1E-6 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS14110 7912d7961686f706509f3028f0a2313d 1016 SUPERFAMILY SSF82714 186 268 3.79E-10 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS14110 7912d7961686f706509f3028f0a2313d 1016 Gene3D G3DSA:3.30.70.1430 40 142 2.0E-25 T 11-11-2016 AUP74_RS14110 7912d7961686f706509f3028f0a2313d 1016 Gene3D G3DSA:3.30.70.1430 556 598 3.0E-5 T 11-11-2016 AUP74_RS14110 7912d7961686f706509f3028f0a2313d 1016 PRINTS PR00702 Acriflavin resistance protein family signature 464 487 1.2E-25 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS14110 7912d7961686f706509f3028f0a2313d 1016 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.2E-25 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS14110 7912d7961686f706509f3028f0a2313d 1016 PRINTS PR00702 Acriflavin resistance protein family signature 386 410 1.2E-25 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS14110 7912d7961686f706509f3028f0a2313d 1016 PRINTS PR00702 Acriflavin resistance protein family signature 332 355 1.2E-25 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS14110 7912d7961686f706509f3028f0a2313d 1016 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.2E-25 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS14110 7912d7961686f706509f3028f0a2313d 1016 Pfam PF00873 AcrB/AcrD/AcrF family 3 1006 7.4E-163 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS14110 7912d7961686f706509f3028f0a2313d 1016 Gene3D G3DSA:1.20.1640.10 293 498 7.5E-44 T 11-11-2016 AUP74_RS14110 7912d7961686f706509f3028f0a2313d 1016 SUPERFAMILY SSF82866 789 1009 1.7E-44 T 11-11-2016 AUP74_RS14110 7912d7961686f706509f3028f0a2313d 1016 Gene3D G3DSA:1.10.3850.10 796 1007 7.8E-55 T 11-11-2016 AUP74_RS08340 076e990c363d0fbdc09c74dcbec2f1b8 462 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 229 236 - T 11-11-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 AUP74_RS08340 076e990c363d0fbdc09c74dcbec2f1b8 462 Pfam PF00171 Aldehyde dehydrogenase family 3 455 6.0E-123 T 11-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 AUP74_RS08340 076e990c363d0fbdc09c74dcbec2f1b8 462 Gene3D G3DSA:3.40.605.10 3 243 9.0E-67 T 11-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AUP74_RS08340 076e990c363d0fbdc09c74dcbec2f1b8 462 SUPERFAMILY SSF53720 3 459 7.2E-134 T 11-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AUP74_RS08340 076e990c363d0fbdc09c74dcbec2f1b8 462 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 257 268 - T 11-11-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 AUP74_RS08340 076e990c363d0fbdc09c74dcbec2f1b8 462 Gene3D G3DSA:3.40.309.10 244 430 1.7E-56 T 11-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 AUP74_RS10815 4e9df601322464448448e4da16f74c29 686 SUPERFAMILY SSF82861 372 453 1.83E-7 T 11-11-2016 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 AUP74_RS10815 4e9df601322464448448e4da16f74c29 686 SUPERFAMILY SSF50182 455 527 9.15E-12 T 11-11-2016 IPR010920 LSM domain AUP74_RS10815 4e9df601322464448448e4da16f74c29 686 Gene3D G3DSA:3.30.70.100 548 610 1.8E-5 T 11-11-2016 AUP74_RS10815 4e9df601322464448448e4da16f74c29 686 Pfam PF00924 Mechanosensitive ion channel 416 616 8.2E-38 T 11-11-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 AUP74_RS10815 4e9df601322464448448e4da16f74c29 686 SUPERFAMILY SSF82689 535 630 6.28E-12 T 11-11-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 AUP74_RS10815 4e9df601322464448448e4da16f74c29 686 Gene3D G3DSA:2.30.30.60 470 526 5.9E-14 T 11-11-2016 AUP74_RS03755 0a9c95ec0b8413c545090b0aeb61f999 249 SUPERFAMILY SSF53335 13 246 6.35E-52 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS03755 0a9c95ec0b8413c545090b0aeb61f999 249 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 156 170 - T 11-11-2016 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 AUP74_RS03755 0a9c95ec0b8413c545090b0aeb61f999 249 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 34 49 - T 11-11-2016 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 AUP74_RS03755 0a9c95ec0b8413c545090b0aeb61f999 249 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 14 248 38.641 T 11-11-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 AUP74_RS03755 0a9c95ec0b8413c545090b0aeb61f999 249 Pfam PF01209 ubiE/COQ5 methyltransferase family 19 248 2.9E-99 T 11-11-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 AUP74_RS03755 0a9c95ec0b8413c545090b0aeb61f999 249 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 23 248 7.2E-82 T 11-11-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 AUP74_RS03755 0a9c95ec0b8413c545090b0aeb61f999 249 Gene3D G3DSA:3.40.50.150 23 245 1.1E-57 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS09680 c7ef0c51d180ad63f1d5cb915035da1c 172 Pfam PF00578 AhpC/TSA family 22 143 4.1E-32 T 11-11-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AUP74_RS09680 c7ef0c51d180ad63f1d5cb915035da1c 172 SUPERFAMILY SSF52833 18 166 3.34E-38 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS09680 c7ef0c51d180ad63f1d5cb915035da1c 172 Gene3D G3DSA:3.40.30.10 17 166 5.0E-39 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS09680 c7ef0c51d180ad63f1d5cb915035da1c 172 PIRSF PIRSF000239 16 172 9.2E-19 T 11-11-2016 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AUP74_RS01865 e4a6911630de254221e7d439c950a8e9 1743 Pfam PF05359 Domain of Unknown Function (DUF748) 1392 1534 4.5E-13 T 11-11-2016 IPR008023 Protein of unknown function DUF748 AUP74_RS01865 e4a6911630de254221e7d439c950a8e9 1743 Gene3D G3DSA:3.30.1330.60 1614 1721 9.2E-9 T 11-11-2016 IPR006665 OmpA-like domain AUP74_RS01865 e4a6911630de254221e7d439c950a8e9 1743 Pfam PF00691 OmpA family 1623 1722 2.8E-5 T 11-11-2016 IPR006665 OmpA-like domain AUP74_RS01865 e4a6911630de254221e7d439c950a8e9 1743 SUPERFAMILY SSF103088 1612 1663 6.67E-5 T 11-11-2016 IPR006665 OmpA-like domain AUP74_RS01865 e4a6911630de254221e7d439c950a8e9 1743 SUPERFAMILY SSF103088 1693 1722 6.67E-5 T 11-11-2016 IPR006665 OmpA-like domain AUP74_RS15485 baaf328944b283193041c4c090033cf6 283 Pfam PF13180 PDZ domain 206 267 1.1E-11 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS15485 baaf328944b283193041c4c090033cf6 283 SUPERFAMILY SSF50156 206 273 1.21E-15 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS15485 baaf328944b283193041c4c090033cf6 283 SMART SM00228 193 265 8.8E-8 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS15485 baaf328944b283193041c4c090033cf6 283 Gene3D G3DSA:2.30.42.10 204 268 6.7E-17 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS03105 294d5a73306bd5b8c1d0e141047cbf81 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 1.1E-10 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS03105 294d5a73306bd5b8c1d0e141047cbf81 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 1.1E-10 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS03105 294d5a73306bd5b8c1d0e141047cbf81 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 1.1E-10 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS03105 294d5a73306bd5b8c1d0e141047cbf81 253 SUPERFAMILY SSF51735 1 252 2.37E-71 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS03105 294d5a73306bd5b8c1d0e141047cbf81 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 4 251 1.7E-54 T 11-11-2016 AUP74_RS03105 294d5a73306bd5b8c1d0e141047cbf81 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 11-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AUP74_RS03105 294d5a73306bd5b8c1d0e141047cbf81 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 8.9E-28 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS03105 294d5a73306bd5b8c1d0e141047cbf81 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 8.9E-28 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS03105 294d5a73306bd5b8c1d0e141047cbf81 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 8.9E-28 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS03105 294d5a73306bd5b8c1d0e141047cbf81 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 8.9E-28 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS03105 294d5a73306bd5b8c1d0e141047cbf81 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 8.9E-28 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS03105 294d5a73306bd5b8c1d0e141047cbf81 253 Gene3D G3DSA:3.40.50.720 1 251 8.6E-75 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS05145 cd669f27644e45345c098d24d714cad1 825 SUPERFAMILY SSF74650 354 816 1.16E-23 T 11-11-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 AUP74_RS05145 cd669f27644e45345c098d24d714cad1 825 SMART SM00872 244 315 6.9E-11 T 11-11-2016 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 AUP74_RS05145 cd669f27644e45345c098d24d714cad1 825 Pfam PF09261 Alpha mannosidase middle domain 245 314 1.4E-6 T 11-11-2016 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 AUP74_RS05145 cd669f27644e45345c098d24d714cad1 825 Gene3D G3DSA:1.20.1270.50 246 330 1.2E-6 T 11-11-2016 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 AUP74_RS05145 cd669f27644e45345c098d24d714cad1 825 Gene3D G3DSA:3.20.110.10 2 232 2.3E-31 T 11-11-2016 IPR027291 Glycoside hydrolase 38/57, N-terminal domain AUP74_RS05145 cd669f27644e45345c098d24d714cad1 825 SUPERFAMILY SSF88688 246 328 5.56E-9 T 11-11-2016 IPR028995 Glycoside hydrolase families 57/38, central domain AUP74_RS05145 cd669f27644e45345c098d24d714cad1 825 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 2 221 2.8E-27 T 11-11-2016 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0005975 AUP74_RS05145 cd669f27644e45345c098d24d714cad1 825 SUPERFAMILY SSF88713 16 231 2.15E-32 T 11-11-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AUP74_RS07020 d6efca7bfed9e205b0f612229e1bdc32 449 SUPERFAMILY SSF53738 151 254 5.89E-28 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS07020 d6efca7bfed9e205b0f612229e1bdc32 449 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 7 135 3.9E-33 T 11-11-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS07020 d6efca7bfed9e205b0f612229e1bdc32 449 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 256 363 1.1E-25 T 11-11-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS07020 d6efca7bfed9e205b0f612229e1bdc32 449 SUPERFAMILY SSF55957 366 448 2.62E-19 T 11-11-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS07020 d6efca7bfed9e205b0f612229e1bdc32 449 SUPERFAMILY SSF53738 256 361 9.42E-33 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS07020 d6efca7bfed9e205b0f612229e1bdc32 449 Gene3D G3DSA:3.30.310.50 368 448 6.5E-21 T 11-11-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS07020 d6efca7bfed9e205b0f612229e1bdc32 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 202 215 9.1E-29 T 11-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS07020 d6efca7bfed9e205b0f612229e1bdc32 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 168 187 9.1E-29 T 11-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS07020 d6efca7bfed9e205b0f612229e1bdc32 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 91 105 9.1E-29 T 11-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS07020 d6efca7bfed9e205b0f612229e1bdc32 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 231 246 9.1E-29 T 11-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS07020 d6efca7bfed9e205b0f612229e1bdc32 449 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 152 251 1.7E-23 T 11-11-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS07020 d6efca7bfed9e205b0f612229e1bdc32 449 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 371 447 1.8E-11 T 11-11-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS07020 d6efca7bfed9e205b0f612229e1bdc32 449 SUPERFAMILY SSF53738 4 175 5.1E-38 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS07020 d6efca7bfed9e205b0f612229e1bdc32 449 Gene3D G3DSA:3.40.120.10 170 247 1.3E-28 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS07020 d6efca7bfed9e205b0f612229e1bdc32 449 Gene3D G3DSA:3.40.120.10 248 360 1.9E-40 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS07020 d6efca7bfed9e205b0f612229e1bdc32 449 Gene3D G3DSA:3.40.120.10 6 139 5.1E-35 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS07020 d6efca7bfed9e205b0f612229e1bdc32 449 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 92 101 - T 11-11-2016 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AUP74_RS01180 45202605a9e2b69973f8f22b9dffa2dc 228 SUPERFAMILY SSF48008 87 220 1.62E-25 T 11-11-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal AUP74_RS01180 45202605a9e2b69973f8f22b9dffa2dc 228 SMART SM00895 91 214 1.2E-21 T 11-11-2016 IPR011711 GntR, C-terminal AUP74_RS01180 45202605a9e2b69973f8f22b9dffa2dc 228 Gene3D G3DSA:1.20.120.530 84 222 1.9E-34 T 11-11-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal AUP74_RS01180 45202605a9e2b69973f8f22b9dffa2dc 228 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 55 4.7E-6 T 11-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AUP74_RS01180 45202605a9e2b69973f8f22b9dffa2dc 228 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 55 71 4.7E-6 T 11-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AUP74_RS01180 45202605a9e2b69973f8f22b9dffa2dc 228 SUPERFAMILY SSF46785 13 85 2.14E-21 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS01180 45202605a9e2b69973f8f22b9dffa2dc 228 SMART SM00345 23 81 5.4E-15 T 11-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AUP74_RS01180 45202605a9e2b69973f8f22b9dffa2dc 228 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 81 2.7E-18 T 11-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AUP74_RS01180 45202605a9e2b69973f8f22b9dffa2dc 228 Pfam PF07729 FCD domain 91 214 7.7E-27 T 11-11-2016 IPR011711 GntR, C-terminal AUP74_RS01180 45202605a9e2b69973f8f22b9dffa2dc 228 Gene3D G3DSA:1.10.10.10 7 82 2.9E-24 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS14870 2d39082b630e5eb6b1addf5d1188d03a 181 Pfam PF09411 Lipid A 3-O-deacylase (PagL) 75 180 9.6E-20 T 11-11-2016 IPR018550 Lipid A 3-O-deacylase-related AUP74_RS14870 2d39082b630e5eb6b1addf5d1188d03a 181 Gene3D G3DSA:2.40.160.20 58 181 8.1E-26 T 11-11-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AUP74_RS13790 2b747724f3c2320d4127a3decefe611f 346 Gene3D G3DSA:3.40.50.2000 143 320 7.5E-31 T 11-11-2016 AUP74_RS13790 2b747724f3c2320d4127a3decefe611f 346 Pfam PF00534 Glycosyl transferases group 1 166 320 3.5E-35 T 11-11-2016 IPR001296 Glycosyl transferase, family 1 AUP74_RS13790 2b747724f3c2320d4127a3decefe611f 346 Pfam PF13439 Glycosyltransferase Family 4 16 153 3.7E-8 T 11-11-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AUP74_RS13790 2b747724f3c2320d4127a3decefe611f 346 SUPERFAMILY SSF53756 5 341 1.16E-72 T 11-11-2016 AUP74_RS08000 92235b747863fa9238baca810d576814 309 SUPERFAMILY SSF52540 1 220 1.7E-65 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS08000 92235b747863fa9238baca810d576814 309 SMART SM00382 25 206 3.8E-14 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS08000 92235b747863fa9238baca810d576814 309 Gene3D G3DSA:3.40.50.300 1 219 3.6E-72 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS08000 92235b747863fa9238baca810d576814 309 Pfam PF00005 ABC transporter 17 160 5.7E-33 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AUP74_RS08000 92235b747863fa9238baca810d576814 309 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 Hamap MF_00938 DNA topoisomerase 4 subunit B [parE]. 1 627 47.066 T 11-11-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 SUPERFAMILY SSF54211 216 380 2.47E-45 T 11-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 SMART SM00433 33 623 9.3E-210 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 ProSitePatterns PS00177 DNA topoisomerase II signature. 415 423 - T 11-11-2016 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 557 619 7.3E-24 T 11-11-2016 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 Gene3D G3DSA:3.30.565.10 14 214 6.1E-76 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 PRINTS PR01098 Topoisomerase IV subunit B signature 447 468 4.4E-111 T 11-11-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 PRINTS PR01098 Topoisomerase IV subunit B signature 468 480 4.4E-111 T 11-11-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 PRINTS PR01098 Topoisomerase IV subunit B signature 237 260 4.4E-111 T 11-11-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 PRINTS PR01098 Topoisomerase IV subunit B signature 134 148 4.4E-111 T 11-11-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 PRINTS PR01098 Topoisomerase IV subunit B signature 502 518 4.4E-111 T 11-11-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 PRINTS PR01098 Topoisomerase IV subunit B signature 337 360 4.4E-111 T 11-11-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 PRINTS PR01098 Topoisomerase IV subunit B signature 310 325 4.4E-111 T 11-11-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 PRINTS PR01098 Topoisomerase IV subunit B signature 293 309 4.4E-111 T 11-11-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 PRINTS PR01098 Topoisomerase IV subunit B signature 191 212 4.4E-111 T 11-11-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 PRINTS PR01098 Topoisomerase IV subunit B signature 25 38 4.4E-111 T 11-11-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 PRINTS PR01098 Topoisomerase IV subunit B signature 361 386 4.4E-111 T 11-11-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 PRINTS PR01098 Topoisomerase IV subunit B signature 173 190 4.4E-111 T 11-11-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 PRINTS PR01098 Topoisomerase IV subunit B signature 536 558 4.4E-111 T 11-11-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 PRINTS PR01098 Topoisomerase IV subunit B signature 148 163 4.4E-111 T 11-11-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 TIGRFAM TIGR01055 parE_Gneg: DNA topoisomerase IV, B subunit 2 623 0.0 T 11-11-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 27 146 1.8E-18 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 Gene3D G3DSA:3.30.230.10 215 389 1.9E-47 T 11-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 SUPERFAMILY SSF56719 387 620 1.15E-77 T 11-11-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 Gene3D G3DSA:3.40.50.670 397 610 3.8E-75 T 11-11-2016 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 PRINTS PR00418 DNA topoisomerase II family signature 65 78 3.1E-58 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 PRINTS PR00418 DNA topoisomerase II family signature 478 494 3.1E-58 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 PRINTS PR00418 DNA topoisomerase II family signature 265 278 3.1E-58 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 PRINTS PR00418 DNA topoisomerase II family signature 30 45 3.1E-58 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 PRINTS PR00418 DNA topoisomerase II family signature 413 427 3.1E-58 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 PRINTS PR00418 DNA topoisomerase II family signature 561 577 3.1E-58 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 PRINTS PR00418 DNA topoisomerase II family signature 108 122 3.1E-58 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 PRINTS PR00418 DNA topoisomerase II family signature 496 513 3.1E-58 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 PRINTS PR00418 DNA topoisomerase II family signature 516 528 3.1E-58 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 SMART SM00387 26 172 6.6E-20 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 SUPERFAMILY SSF55874 4 214 1.83E-67 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 Pfam PF01751 Toprim domain 412 521 6.4E-13 T 11-11-2016 IPR006171 Toprim domain AUP74_RS02135 6714cd59bc9b74c616a9e86d2b96d52e 628 Pfam PF00204 DNA gyrase B 217 383 2.7E-39 T 11-11-2016 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AUP74_RS01910 a58a29ed0b972cac1cd6eb159cd9c36b 280 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 133 161 - T 11-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AUP74_RS01910 a58a29ed0b972cac1cd6eb159cd9c36b 280 Pfam PF00106 short chain dehydrogenase 5 184 4.3E-49 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS01910 a58a29ed0b972cac1cd6eb159cd9c36b 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 2.5E-25 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS01910 a58a29ed0b972cac1cd6eb159cd9c36b 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.5E-25 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS01910 a58a29ed0b972cac1cd6eb159cd9c36b 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 2.5E-25 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS01910 a58a29ed0b972cac1cd6eb159cd9c36b 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 2.5E-25 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS01910 a58a29ed0b972cac1cd6eb159cd9c36b 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 2.5E-25 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS01910 a58a29ed0b972cac1cd6eb159cd9c36b 280 SUPERFAMILY SSF51735 2 273 3.68E-66 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS01910 a58a29ed0b972cac1cd6eb159cd9c36b 280 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 175 3.5E-4 T 11-11-2016 AUP74_RS01910 a58a29ed0b972cac1cd6eb159cd9c36b 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 3.5E-10 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS01910 a58a29ed0b972cac1cd6eb159cd9c36b 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 3.5E-10 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS01910 a58a29ed0b972cac1cd6eb159cd9c36b 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 3.5E-10 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS01910 a58a29ed0b972cac1cd6eb159cd9c36b 280 Gene3D G3DSA:3.40.50.720 3 271 4.3E-70 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS02545 ff09e49728c137516ff762df7a4afa87 247 Gene3D G3DSA:3.40.50.150 53 243 2.7E-22 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS02545 ff09e49728c137516ff762df7a4afa87 247 SUPERFAMILY SSF53335 51 241 2.44E-19 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS03265 4b65372b61ddff1d06a62bc13899f436 93 Pfam PF04362 Bacterial Fe(2+) trafficking 1 88 5.3E-43 T 11-11-2016 IPR007457 Fe(II) trafficking protein YggX GO:0005506 AUP74_RS03265 4b65372b61ddff1d06a62bc13899f436 93 Hamap MF_00686 Probable Fe(2+)-trafficking protein [yggX]. 1 88 27.822 T 11-11-2016 IPR007457 Fe(II) trafficking protein YggX GO:0005506 AUP74_RS03265 4b65372b61ddff1d06a62bc13899f436 93 ProDom PD029191 TRAFFICKING IRON PROBABLE FE2 YGGX FEII 3D-STRUCTURE OXIDATIVE CONTROL DIRECT 1 73 2.0E-26 T 11-11-2016 IPR007457 Fe(II) trafficking protein YggX GO:0005506 AUP74_RS03265 4b65372b61ddff1d06a62bc13899f436 93 Gene3D G3DSA:1.10.3880.10 1 91 7.8E-43 T 11-11-2016 AUP74_RS03265 4b65372b61ddff1d06a62bc13899f436 93 SUPERFAMILY SSF111148 1 90 2.75E-41 T 11-11-2016 IPR007457 Fe(II) trafficking protein YggX GO:0005506 AUP74_RS03265 4b65372b61ddff1d06a62bc13899f436 93 PIRSF PIRSF029827 1 90 8.3E-41 T 11-11-2016 IPR007457 Fe(II) trafficking protein YggX GO:0005506 AUP74_RS08625 c2a085083ee907c3b679cf3f4270ce17 136 SUPERFAMILY SSF51316 9 131 2.09E-32 T 11-11-2016 IPR011057 Mss4-like AUP74_RS08625 c2a085083ee907c3b679cf3f4270ce17 136 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 38 114 3.2E-10 T 11-11-2016 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 AUP74_RS08625 c2a085083ee907c3b679cf3f4270ce17 136 Gene3D G3DSA:3.90.1590.10 14 113 5.3E-19 T 11-11-2016 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 AUP74_RS05180 4a3e63e299e25e8b5af1e6c7bf1ef59a 193 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 2 179 2.0E-57 T 11-11-2016 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG AUP74_RS05180 4a3e63e299e25e8b5af1e6c7bf1ef59a 193 Gene3D G3DSA:3.40.50.450 2 188 4.0E-72 T 11-11-2016 AUP74_RS05180 4a3e63e299e25e8b5af1e6c7bf1ef59a 193 SUPERFAMILY SSF102405 1 179 6.11E-60 T 11-11-2016 AUP74_RS05180 4a3e63e299e25e8b5af1e6c7bf1ef59a 193 Pfam PF03641 Possible lysine decarboxylase 46 176 9.3E-43 T 11-11-2016 IPR031100 LOG family AUP74_RS08855 76fbe8b41a8455320f754414d2686ac0 160 SUPERFAMILY SSF53756 22 139 4.85E-11 T 11-11-2016 AUP74_RS08855 76fbe8b41a8455320f754414d2686ac0 160 Gene3D G3DSA:3.40.50.2000 2 157 1.0E-22 T 11-11-2016 AUP74_RS08855 76fbe8b41a8455320f754414d2686ac0 160 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 2 135 1.2E-17 T 11-11-2016 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 AUP74_RS03705 614c4e7426a0ba10579f82a0aaf1cb9d 129 SUPERFAMILY SSF141488 29 105 1.57E-13 T 11-11-2016 IPR018660 C-type lysozyme, inhibitor AUP74_RS03705 614c4e7426a0ba10579f82a0aaf1cb9d 129 Pfam PF09864 Membrane-bound lysozyme-inhibitor of c-type lysozyme 35 103 1.9E-14 T 11-11-2016 IPR018660 C-type lysozyme, inhibitor AUP74_RS07440 27e82a595941c4a57783e265a51b511f 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 6.1E-7 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS07440 27e82a595941c4a57783e265a51b511f 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 6.1E-7 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS07440 27e82a595941c4a57783e265a51b511f 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 6.1E-7 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS07440 27e82a595941c4a57783e265a51b511f 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 2.3E-31 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS07440 27e82a595941c4a57783e265a51b511f 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 2.3E-31 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS07440 27e82a595941c4a57783e265a51b511f 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.3E-31 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS07440 27e82a595941c4a57783e265a51b511f 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.3E-31 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS07440 27e82a595941c4a57783e265a51b511f 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 2.3E-31 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS07440 27e82a595941c4a57783e265a51b511f 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 2.3E-31 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS07440 27e82a595941c4a57783e265a51b511f 264 SUPERFAMILY SSF51735 6 259 8.11E-64 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS07440 27e82a595941c4a57783e265a51b511f 264 Gene3D G3DSA:3.40.50.720 2 260 5.6E-68 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS07440 27e82a595941c4a57783e265a51b511f 264 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 259 9.7E-45 T 11-11-2016 AUP74_RS04625 01b349c6c16202a7d0e9f82a2fb2a5e9 325 Gene3D G3DSA:1.10.10.10 3 85 1.3E-25 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS04625 01b349c6c16202a7d0e9f82a2fb2a5e9 325 Gene3D G3DSA:3.40.190.10 171 264 1.0E-19 T 11-11-2016 AUP74_RS04625 01b349c6c16202a7d0e9f82a2fb2a5e9 325 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 7.9E-22 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS04625 01b349c6c16202a7d0e9f82a2fb2a5e9 325 SUPERFAMILY SSF46785 6 84 6.65E-22 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS04625 01b349c6c16202a7d0e9f82a2fb2a5e9 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 2.1E-8 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS04625 01b349c6c16202a7d0e9f82a2fb2a5e9 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 2.1E-8 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS04625 01b349c6c16202a7d0e9f82a2fb2a5e9 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 2.1E-8 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS04625 01b349c6c16202a7d0e9f82a2fb2a5e9 325 Pfam PF03466 LysR substrate binding domain 93 292 8.5E-28 T 11-11-2016 IPR005119 LysR, substrate-binding AUP74_RS04625 01b349c6c16202a7d0e9f82a2fb2a5e9 325 Gene3D G3DSA:3.40.190.10 90 170 3.3E-13 T 11-11-2016 AUP74_RS04625 01b349c6c16202a7d0e9f82a2fb2a5e9 325 SUPERFAMILY SSF53850 93 295 2.71E-29 T 11-11-2016 AUP74_RS11185 e4dc1858bf498dcebd181bb249080569 715 Gene3D G3DSA:3.40.50.720 307 499 4.3E-57 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS11185 e4dc1858bf498dcebd181bb249080569 715 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 206 2.3E-36 T 11-11-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 AUP74_RS11185 e4dc1858bf498dcebd181bb249080569 715 SUPERFAMILY SSF48179 497 611 1.36E-29 T 11-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AUP74_RS11185 e4dc1858bf498dcebd181bb249080569 715 Gene3D G3DSA:1.10.1040.10 500 594 2.4E-22 T 11-11-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AUP74_RS11185 e4dc1858bf498dcebd181bb249080569 715 Gene3D G3DSA:1.10.1040.10 634 713 6.6E-19 T 11-11-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AUP74_RS11185 e4dc1858bf498dcebd181bb249080569 715 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 495 519 - T 11-11-2016 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 AUP74_RS11185 e4dc1858bf498dcebd181bb249080569 715 SUPERFAMILY SSF52096 3 307 1.1E-64 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS11185 e4dc1858bf498dcebd181bb249080569 715 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 318 496 1.4E-59 T 11-11-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 AUP74_RS11185 e4dc1858bf498dcebd181bb249080569 715 SUPERFAMILY SSF51735 314 497 4.67E-55 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS11185 e4dc1858bf498dcebd181bb249080569 715 TIGRFAM TIGR02437 FadB: fatty oxidation complex, alpha subunit FadB 1 715 0.0 T 11-11-2016 IPR012799 Fatty oxidation complex, alpha subunit FadB GO:0003857|GO:0004165|GO:0004300|GO:0008692|GO:0009062|GO:0036125|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35+5.3.3.8|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5137|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6837|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-7291|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 AUP74_RS11185 e4dc1858bf498dcebd181bb249080569 715 Gene3D G3DSA:3.90.226.10 236 299 7.7E-55 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS11185 e4dc1858bf498dcebd181bb249080569 715 Gene3D G3DSA:3.90.226.10 10 202 7.7E-55 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS11185 e4dc1858bf498dcebd181bb249080569 715 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 498 593 1.5E-25 T 11-11-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 AUP74_RS11185 e4dc1858bf498dcebd181bb249080569 715 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 628 712 9.1E-7 T 11-11-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 AUP74_RS11185 e4dc1858bf498dcebd181bb249080569 715 SUPERFAMILY SSF48179 625 715 1.19E-25 T 11-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AUP74_RS00990 691bb2129a1e7be909406f8855886e7d 340 SUPERFAMILY SSF56300 39 160 1.64E-33 T 11-11-2016 IPR029052 Metallo-dependent phosphatase-like AUP74_RS00990 691bb2129a1e7be909406f8855886e7d 340 SUPERFAMILY SSF56300 201 279 1.64E-33 T 11-11-2016 IPR029052 Metallo-dependent phosphatase-like AUP74_RS00990 691bb2129a1e7be909406f8855886e7d 340 Gene3D G3DSA:3.60.21.10 36 160 1.2E-33 T 11-11-2016 IPR029052 Metallo-dependent phosphatase-like AUP74_RS00990 691bb2129a1e7be909406f8855886e7d 340 Gene3D G3DSA:3.60.21.10 201 287 1.2E-33 T 11-11-2016 IPR029052 Metallo-dependent phosphatase-like AUP74_RS00990 691bb2129a1e7be909406f8855886e7d 340 Pfam PF00149 Calcineurin-like phosphoesterase 41 260 4.2E-9 T 11-11-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 AUP74_RS07480 2ead1b272d54a8100b74b3504762e98a 408 Gene3D G3DSA:3.30.470.20 108 305 3.5E-11 T 11-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 AUP74_RS07480 2ead1b272d54a8100b74b3504762e98a 408 SUPERFAMILY SSF56059 108 306 1.46E-20 T 11-11-2016 AUP74_RS14335 829b3ffc6add21297e7f82f2318159b8 333 Gene3D G3DSA:3.40.1190.20 4 327 3.2E-71 T 11-11-2016 IPR029056 Ribokinase-like AUP74_RS14335 829b3ffc6add21297e7f82f2318159b8 333 SUPERFAMILY SSF53613 1 319 6.24E-76 T 11-11-2016 IPR029056 Ribokinase-like AUP74_RS14335 829b3ffc6add21297e7f82f2318159b8 333 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 274 287 - T 11-11-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 AUP74_RS14335 829b3ffc6add21297e7f82f2318159b8 333 Pfam PF00294 pfkB family carbohydrate kinase 57 318 1.6E-58 T 11-11-2016 IPR011611 Carbohydrate kinase PfkB AUP74_RS14335 829b3ffc6add21297e7f82f2318159b8 333 PRINTS PR00990 Ribokinase signature 207 222 3.9E-5 T 11-11-2016 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 AUP74_RS14335 829b3ffc6add21297e7f82f2318159b8 333 PRINTS PR00990 Ribokinase signature 245 256 3.9E-5 T 11-11-2016 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 AUP74_RS14335 829b3ffc6add21297e7f82f2318159b8 333 PRINTS PR00990 Ribokinase signature 57 76 3.9E-5 T 11-11-2016 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 AUP74_RS16180 e1dc8cbd7d5104ffa7fe0a430b00b5e2 637 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 30 186 1.1E-15 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS16180 e1dc8cbd7d5104ffa7fe0a430b00b5e2 637 SUPERFAMILY SSF110942 521 633 4.97E-35 T 11-11-2016 AUP74_RS16180 e1dc8cbd7d5104ffa7fe0a430b00b5e2 637 SUPERFAMILY SSF54211 239 494 3.19E-97 T 11-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold AUP74_RS16180 e1dc8cbd7d5104ffa7fe0a430b00b5e2 637 PRINTS PR00775 90kDa heat shock protein signature 8 28 9.6E-61 T 11-11-2016 IPR020575 Heat shock protein Hsp90, N-terminal AUP74_RS16180 e1dc8cbd7d5104ffa7fe0a430b00b5e2 637 PRINTS PR00775 90kDa heat shock protein signature 123 145 9.6E-61 T 11-11-2016 IPR020575 Heat shock protein Hsp90, N-terminal AUP74_RS16180 e1dc8cbd7d5104ffa7fe0a430b00b5e2 637 PRINTS PR00775 90kDa heat shock protein signature 78 95 9.6E-61 T 11-11-2016 IPR020575 Heat shock protein Hsp90, N-terminal AUP74_RS16180 e1dc8cbd7d5104ffa7fe0a430b00b5e2 637 PRINTS PR00775 90kDa heat shock protein signature 96 113 9.6E-61 T 11-11-2016 IPR020575 Heat shock protein Hsp90, N-terminal AUP74_RS16180 e1dc8cbd7d5104ffa7fe0a430b00b5e2 637 PRINTS PR00775 90kDa heat shock protein signature 175 192 9.6E-61 T 11-11-2016 IPR020575 Heat shock protein Hsp90, N-terminal AUP74_RS16180 e1dc8cbd7d5104ffa7fe0a430b00b5e2 637 PRINTS PR00775 90kDa heat shock protein signature 193 211 9.6E-61 T 11-11-2016 IPR020575 Heat shock protein Hsp90, N-terminal AUP74_RS16180 e1dc8cbd7d5104ffa7fe0a430b00b5e2 637 PRINTS PR00775 90kDa heat shock protein signature 29 51 9.6E-61 T 11-11-2016 IPR020575 Heat shock protein Hsp90, N-terminal AUP74_RS16180 e1dc8cbd7d5104ffa7fe0a430b00b5e2 637 Gene3D G3DSA:3.30.565.10 7 217 1.5E-83 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS16180 e1dc8cbd7d5104ffa7fe0a430b00b5e2 637 PIRSF PIRSF002583 2 637 2.4E-218 T 11-11-2016 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 AUP74_RS16180 e1dc8cbd7d5104ffa7fe0a430b00b5e2 637 Pfam PF00183 Hsp90 protein 220 632 6.0E-128 T 11-11-2016 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 AUP74_RS16180 e1dc8cbd7d5104ffa7fe0a430b00b5e2 637 Hamap MF_00505 Chaperone protein HtpG [htpG]. 5 633 32.334 T 11-11-2016 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 AUP74_RS16180 e1dc8cbd7d5104ffa7fe0a430b00b5e2 637 SMART SM00387 30 187 4.4E-11 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS16180 e1dc8cbd7d5104ffa7fe0a430b00b5e2 637 SUPERFAMILY SSF55874 8 217 1.18E-67 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS16180 e1dc8cbd7d5104ffa7fe0a430b00b5e2 637 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 28 37 - T 11-11-2016 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0006950|GO:0051082 AUP74_RS15965 8ec4b2940d62373d5f622628b44e0f56 220 Pfam PF12697 Alpha/beta hydrolase family 44 212 1.6E-9 T 11-11-2016 IPR000073 Alpha/beta hydrolase fold-1 AUP74_RS15965 8ec4b2940d62373d5f622628b44e0f56 220 Gene3D G3DSA:3.40.50.1820 13 219 6.6E-32 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS15965 8ec4b2940d62373d5f622628b44e0f56 220 SUPERFAMILY SSF53474 28 218 4.09E-30 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS10175 a1c614d5e3ca180d4f47dcb1273f0a8b 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.2E-40 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS10175 a1c614d5e3ca180d4f47dcb1273f0a8b 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 1.2E-40 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS10175 a1c614d5e3ca180d4f47dcb1273f0a8b 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.2E-40 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS10175 a1c614d5e3ca180d4f47dcb1273f0a8b 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.2E-40 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS10175 a1c614d5e3ca180d4f47dcb1273f0a8b 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.2E-40 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS10175 a1c614d5e3ca180d4f47dcb1273f0a8b 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.2E-40 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS10175 a1c614d5e3ca180d4f47dcb1273f0a8b 258 Gene3D G3DSA:3.40.50.720 4 254 1.0E-86 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS10175 a1c614d5e3ca180d4f47dcb1273f0a8b 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 11-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AUP74_RS10175 a1c614d5e3ca180d4f47dcb1273f0a8b 258 SUPERFAMILY SSF51735 10 254 2.35E-86 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS10175 a1c614d5e3ca180d4f47dcb1273f0a8b 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 253 2.2E-65 T 11-11-2016 AUP74_RS10175 a1c614d5e3ca180d4f47dcb1273f0a8b 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 6.9E-11 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS10175 a1c614d5e3ca180d4f47dcb1273f0a8b 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 6.9E-11 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS10175 a1c614d5e3ca180d4f47dcb1273f0a8b 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 6.9E-11 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS16045 a9630ecf94e818c78a98d2a01c8e7729 395 Gene3D G3DSA:3.90.1150.10 258 393 3.9E-50 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS16045 a9630ecf94e818c78a98d2a01c8e7729 395 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 10 390 7.3E-142 T 11-11-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AUP74_RS16045 a9630ecf94e818c78a98d2a01c8e7729 395 Hamap MF_02056 O-succinylhomoserine sulfhydrylase [metZ]. 11 391 52.817 T 11-11-2016 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 AUP74_RS16045 a9630ecf94e818c78a98d2a01c8e7729 395 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 201 215 - T 11-11-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AUP74_RS16045 a9630ecf94e818c78a98d2a01c8e7729 395 TIGRFAM TIGR01325 O_suc_HS_sulf: O-succinylhomoserine sulfhydrylase 10 390 8.9E-176 T 11-11-2016 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 AUP74_RS16045 a9630ecf94e818c78a98d2a01c8e7729 395 PIRSF PIRSF001434 3 394 2.3E-132 T 11-11-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AUP74_RS16045 a9630ecf94e818c78a98d2a01c8e7729 395 SUPERFAMILY SSF53383 29 392 1.02E-118 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase AUP74_RS16045 a9630ecf94e818c78a98d2a01c8e7729 395 Gene3D G3DSA:3.40.640.10 8 256 1.7E-94 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AUP74_RS12110 7a463aef6451a1c29921c2b086ca6363 800 ProSitePatterns PS00116 DNA polymerase family B signature. 555 563 - T 11-11-2016 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS12110 7a463aef6451a1c29921c2b086ca6363 800 Gene3D G3DSA:3.30.420.10 187 341 1.8E-32 T 11-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 AUP74_RS12110 7a463aef6451a1c29921c2b086ca6363 800 SUPERFAMILY SSF56672 381 791 1.17E-117 T 11-11-2016 AUP74_RS12110 7a463aef6451a1c29921c2b086ca6363 800 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 498 510 1.7E-10 T 11-11-2016 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS12110 7a463aef6451a1c29921c2b086ca6363 800 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 553 561 1.7E-10 T 11-11-2016 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS12110 7a463aef6451a1c29921c2b086ca6363 800 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 411 424 1.7E-10 T 11-11-2016 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS12110 7a463aef6451a1c29921c2b086ca6363 800 SMART SM00486 149 567 6.5E-57 T 11-11-2016 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS12110 7a463aef6451a1c29921c2b086ca6363 800 Pfam PF03104 DNA polymerase family B, exonuclease domain 184 290 1.7E-8 T 11-11-2016 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS12110 7a463aef6451a1c29921c2b086ca6363 800 Pfam PF00136 DNA polymerase family B 373 749 8.8E-43 T 11-11-2016 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS12110 7a463aef6451a1c29921c2b086ca6363 800 Gene3D G3DSA:1.10.287.690 474 513 0.001 T 11-11-2016 AUP74_RS12110 7a463aef6451a1c29921c2b086ca6363 800 Gene3D G3DSA:3.90.1600.10 397 427 3.1E-11 T 11-11-2016 IPR023211 DNA polymerase, palm domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS12110 7a463aef6451a1c29921c2b086ca6363 800 Gene3D G3DSA:3.90.1600.10 521 660 3.1E-11 T 11-11-2016 IPR023211 DNA polymerase, palm domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS12110 7a463aef6451a1c29921c2b086ca6363 800 SUPERFAMILY SSF53098 3 385 8.13E-71 T 11-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 AUP74_RS16645 4da1d4a0f2f6fe0211a5c821474f3f67 1055 SUPERFAMILY SSF50249 951 1045 7.59E-5 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS16645 4da1d4a0f2f6fe0211a5c821474f3f67 1055 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 293 715 2.4E-141 T 11-11-2016 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS16645 4da1d4a0f2f6fe0211a5c821474f3f67 1055 Pfam PF01336 OB-fold nucleic acid binding domain 961 1041 2.1E-9 T 11-11-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 AUP74_RS16645 4da1d4a0f2f6fe0211a5c821474f3f67 1055 SMART SM00481 4 76 1.3E-6 T 11-11-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 AUP74_RS16645 4da1d4a0f2f6fe0211a5c821474f3f67 1055 Gene3D G3DSA:3.20.20.140 10 77 2.6E-5 T 11-11-2016 AUP74_RS16645 4da1d4a0f2f6fe0211a5c821474f3f67 1055 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 4 888 3.0E-156 T 11-11-2016 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS16645 4da1d4a0f2f6fe0211a5c821474f3f67 1055 Gene3D G3DSA:2.40.50.140 949 1045 7.9E-9 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS16645 4da1d4a0f2f6fe0211a5c821474f3f67 1055 SUPERFAMILY SSF89550 10 52 4.32E-5 T 11-11-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AUP74_RS16645 4da1d4a0f2f6fe0211a5c821474f3f67 1055 Pfam PF14579 Helix-hairpin-helix motif 788 888 2.1E-13 T 11-11-2016 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS16645 4da1d4a0f2f6fe0211a5c821474f3f67 1055 Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. 3 1055 12.97 T 11-11-2016 IPR023073 DNA polymerase, error-prone GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS16645 4da1d4a0f2f6fe0211a5c821474f3f67 1055 Pfam PF02811 PHP domain 8 143 7.5E-15 T 11-11-2016 IPR004013 PHP domain GO:0003824 AUP74_RS06700 491fe448af2485c043b1b29bdc467c24 396 PRINTS PR00173 Glutamate-aspartate symporter signature 30 50 4.3E-5 T 11-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AUP74_RS06700 491fe448af2485c043b1b29bdc467c24 396 PRINTS PR00173 Glutamate-aspartate symporter signature 368 387 4.3E-5 T 11-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AUP74_RS06700 491fe448af2485c043b1b29bdc467c24 396 PRINTS PR00173 Glutamate-aspartate symporter signature 275 294 4.3E-5 T 11-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AUP74_RS06700 491fe448af2485c043b1b29bdc467c24 396 Pfam PF12698 ABC-2 family transporter protein 36 380 8.4E-12 T 11-11-2016 AUP74_RS03855 48afa047d912b349c404899f7aa2003e 417 Gene3D G3DSA:3.40.50.720 161 410 1.1E-82 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS03855 48afa047d912b349c404899f7aa2003e 417 Gene3D G3DSA:3.40.50.10380 7 160 5.8E-48 T 11-11-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 AUP74_RS03855 48afa047d912b349c404899f7aa2003e 417 SUPERFAMILY SSF51735 163 411 2.43E-78 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS03855 48afa047d912b349c404899f7aa2003e 417 SMART SM00919 163 399 2.0E-132 T 11-11-2016 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 AUP74_RS03855 48afa047d912b349c404899f7aa2003e 417 SUPERFAMILY SSF53223 10 161 1.65E-50 T 11-11-2016 AUP74_RS03855 48afa047d912b349c404899f7aa2003e 417 PIRSF PIRSF000106 30 413 1.1E-68 T 11-11-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 AUP74_RS03855 48afa047d912b349c404899f7aa2003e 417 ProSitePatterns PS00331 Malic enzymes signature. 159 175 - T 11-11-2016 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 AUP74_RS03855 48afa047d912b349c404899f7aa2003e 417 SMART SM01274 18 151 7.2E-77 T 11-11-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 AUP74_RS03855 48afa047d912b349c404899f7aa2003e 417 Pfam PF00390 Malic enzyme, N-terminal domain 23 149 1.1E-25 T 11-11-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 AUP74_RS03855 48afa047d912b349c404899f7aa2003e 417 Pfam PF03949 Malic enzyme, NAD binding domain 165 353 1.8E-23 T 11-11-2016 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 AUP74_RS04575 197fcf5c6529d43863fe681e628c0abc 355 SUPERFAMILY SSF54106 31 79 1.57E-7 T 11-11-2016 IPR018392 LysM domain AUP74_RS04575 197fcf5c6529d43863fe681e628c0abc 355 SMART SM00257 32 80 4.5E-4 T 11-11-2016 IPR018392 LysM domain AUP74_RS04575 197fcf5c6529d43863fe681e628c0abc 355 Gene3D G3DSA:3.10.350.10 32 79 1.3E-8 T 11-11-2016 IPR018392 LysM domain AUP74_RS04575 197fcf5c6529d43863fe681e628c0abc 355 Pfam PF01476 LysM domain 33 78 1.1E-10 T 11-11-2016 IPR018392 LysM domain AUP74_RS04210 74f61316566599289b76a4bd64bd4eb4 350 Gene3D G3DSA:3.40.190.10 27 183 2.4E-28 T 11-11-2016 AUP74_RS04210 74f61316566599289b76a4bd64bd4eb4 350 SUPERFAMILY SSF53850 26 339 4.13E-67 T 11-11-2016 AUP74_RS04210 74f61316566599289b76a4bd64bd4eb4 350 Pfam PF12849 PBP superfamily domain 18 309 1.2E-41 T 11-11-2016 IPR024370 PBP domain AUP74_RS13560 827a2bea4515c38d60995a91b523d2ef 413 Pfam PF02308 MgtC family 8 128 2.3E-18 T 11-11-2016 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 AUP74_RS13560 827a2bea4515c38d60995a91b523d2ef 413 Pfam PF13194 Domain of unknown function (DUF4010) 176 384 2.4E-64 T 11-11-2016 IPR025105 Domain of unknown function DUF4010 AUP74_RS14405 91b4ce8eb30b635d0170010ebd04bd06 222 Gene3D G3DSA:1.20.1050.10 91 212 5.0E-10 T 11-11-2016 IPR010987 Glutathione S-transferase, C-terminal-like AUP74_RS14405 91b4ce8eb30b635d0170010ebd04bd06 222 SUPERFAMILY SSF52833 1 101 6.87E-20 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS14405 91b4ce8eb30b635d0170010ebd04bd06 222 Pfam PF00043 Glutathione S-transferase, C-terminal domain 147 197 3.1E-6 T 11-11-2016 IPR004046 Glutathione S-transferase, C-terminal AUP74_RS14405 91b4ce8eb30b635d0170010ebd04bd06 222 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 75 3.9E-15 T 11-11-2016 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 AUP74_RS14405 91b4ce8eb30b635d0170010ebd04bd06 222 SUPERFAMILY SSF47616 69 212 7.39E-13 T 11-11-2016 IPR010987 Glutathione S-transferase, C-terminal-like AUP74_RS14405 91b4ce8eb30b635d0170010ebd04bd06 222 Gene3D G3DSA:3.40.30.10 1 90 2.6E-23 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS05745 3188c2c4e3b1fc1fa647ca05ac3cfa39 728 TIGRFAM TIGR02515 IV_pilus_PilQ: type IV pilus secretin PilQ 279 721 8.6E-160 T 11-11-2016 IPR013355 Type IV pilus secretin PilQ GO:0009297|GO:0009306 AUP74_RS05745 3188c2c4e3b1fc1fa647ca05ac3cfa39 728 PRINTS PR00811 Bacterial general secretion pathway protein D signature 685 703 8.6E-18 T 11-11-2016 IPR001775 GspD/PilQ family AUP74_RS05745 3188c2c4e3b1fc1fa647ca05ac3cfa39 728 PRINTS PR00811 Bacterial general secretion pathway protein D signature 556 580 8.6E-18 T 11-11-2016 IPR001775 GspD/PilQ family AUP74_RS05745 3188c2c4e3b1fc1fa647ca05ac3cfa39 728 PRINTS PR00811 Bacterial general secretion pathway protein D signature 464 474 8.6E-18 T 11-11-2016 IPR001775 GspD/PilQ family AUP74_RS05745 3188c2c4e3b1fc1fa647ca05ac3cfa39 728 PRINTS PR00811 Bacterial general secretion pathway protein D signature 708 722 8.6E-18 T 11-11-2016 IPR001775 GspD/PilQ family AUP74_RS05745 3188c2c4e3b1fc1fa647ca05ac3cfa39 728 Pfam PF03958 Bacterial type II/III secretion system short domain 378 464 7.6E-12 T 11-11-2016 IPR005644 NolW-like AUP74_RS05745 3188c2c4e3b1fc1fa647ca05ac3cfa39 728 Pfam PF00263 Bacterial type II and III secretion system protein 560 720 9.9E-48 T 11-11-2016 IPR004846 Type II/III secretion system GO:0009306 AUP74_RS05745 3188c2c4e3b1fc1fa647ca05ac3cfa39 728 Pfam PF11741 AMIN domain 37 121 1.9E-7 T 11-11-2016 IPR021731 AMIN domain AUP74_RS05745 3188c2c4e3b1fc1fa647ca05ac3cfa39 728 SMART SM00965 304 352 8.0E-11 T 11-11-2016 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 AUP74_RS05745 3188c2c4e3b1fc1fa647ca05ac3cfa39 728 Pfam PF07660 Secretin and TonB N terminus short domain 305 351 1.6E-8 T 11-11-2016 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 AUP74_RS05745 3188c2c4e3b1fc1fa647ca05ac3cfa39 728 ProSitePatterns PS00875 Bacterial type II secretion system protein D signature. 666 699 - T 11-11-2016 IPR004845 Type II secretion system GspD, conserved site GO:0008565 AUP74_RS00025 e39f8c62d0460ac57ebe4b92b0f2ee92 96 SUPERFAMILY SSF69754 2 96 1.31E-32 T 11-11-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 AUP74_RS00025 e39f8c62d0460ac57ebe4b92b0f2ee92 96 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 95 1.6E-29 T 11-11-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 AUP74_RS00025 e39f8c62d0460ac57ebe4b92b0f2ee92 96 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 93 3.4E-27 T 11-11-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 AUP74_RS00025 e39f8c62d0460ac57ebe4b92b0f2ee92 96 Gene3D G3DSA:3.30.160.100 1 95 9.1E-35 T 11-11-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 AUP74_RS06310 c106d40f27910a76e5d7e2b2879072af 622 SUPERFAMILY SSF88659 461 534 4.67E-21 T 11-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS06310 c106d40f27910a76e5d7e2b2879072af 622 SUPERFAMILY SSF88659 518 620 6.54E-26 T 11-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS06310 c106d40f27910a76e5d7e2b2879072af 622 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 581 607 - T 11-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS06310 c106d40f27910a76e5d7e2b2879072af 622 Gene3D G3DSA:1.10.10.10 461 512 8.9E-28 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS06310 c106d40f27910a76e5d7e2b2879072af 622 PRINTS PR00046 Major sigma-70 factor signature 560 572 6.8E-31 T 11-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS06310 c106d40f27910a76e5d7e2b2879072af 622 PRINTS PR00046 Major sigma-70 factor signature 596 607 6.8E-31 T 11-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS06310 c106d40f27910a76e5d7e2b2879072af 622 PRINTS PR00046 Major sigma-70 factor signature 581 596 6.8E-31 T 11-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS06310 c106d40f27910a76e5d7e2b2879072af 622 PRINTS PR00046 Major sigma-70 factor signature 412 425 6.8E-31 T 11-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS06310 c106d40f27910a76e5d7e2b2879072af 622 PRINTS PR00046 Major sigma-70 factor signature 436 444 6.8E-31 T 11-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS06310 c106d40f27910a76e5d7e2b2879072af 622 Gene3D G3DSA:1.10.10.10 552 621 9.1E-33 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS06310 c106d40f27910a76e5d7e2b2879072af 622 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 412 425 - T 11-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS06310 c106d40f27910a76e5d7e2b2879072af 622 Gene3D G3DSA:1.10.601.10 115 457 3.2E-125 T 11-11-2016 AUP74_RS06310 c106d40f27910a76e5d7e2b2879072af 622 Pfam PF03979 Sigma-70 factor, region 1.1 7 79 1.4E-28 T 11-11-2016 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 AUP74_RS06310 c106d40f27910a76e5d7e2b2879072af 622 Pfam PF04542 Sigma-70 region 2 388 457 1.7E-21 T 11-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS06310 c106d40f27910a76e5d7e2b2879072af 622 Pfam PF00140 Sigma-70 factor, region 1.2 101 133 4.5E-13 T 11-11-2016 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS06310 c106d40f27910a76e5d7e2b2879072af 622 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 384 620 2.3E-121 T 11-11-2016 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 AUP74_RS06310 c106d40f27910a76e5d7e2b2879072af 622 Pfam PF04539 Sigma-70 region 3 467 542 7.5E-31 T 11-11-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS06310 c106d40f27910a76e5d7e2b2879072af 622 SUPERFAMILY SSF88946 118 455 2.62E-101 T 11-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS06310 c106d40f27910a76e5d7e2b2879072af 622 Pfam PF04545 Sigma-70, region 4 556 609 1.3E-18 T 11-11-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS06310 c106d40f27910a76e5d7e2b2879072af 622 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 384 609 7.4E-37 T 11-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS06310 c106d40f27910a76e5d7e2b2879072af 622 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 7 621 44.966 T 11-11-2016 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 AUP74_RS06310 c106d40f27910a76e5d7e2b2879072af 622 Pfam PF04546 Sigma-70, non-essential region 142 356 9.5E-59 T 11-11-2016 IPR007631 RNA polymerase sigma factor 70, non-essential domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS11365 89939ad023d9daca7d24e6a6eea96481 438 Pfam PF09925 Predicted membrane protein (DUF2157) 17 159 3.4E-32 T 11-11-2016 IPR018677 Domain of unknown function DUF2157 AUP74_RS12405 6ca0cb8da462aafe9e278275abf2f433 701 Pfam PF11818 C-terminal domain of tail specific protease (DUF3340) 539 685 9.4E-35 T 11-11-2016 IPR020992 Tail specific protease, C-terminal AUP74_RS12405 6ca0cb8da462aafe9e278275abf2f433 701 Pfam PF03572 Peptidase family S41 361 534 2.6E-49 T 11-11-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 AUP74_RS12405 6ca0cb8da462aafe9e278275abf2f433 701 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 201 556 1.9E-96 T 11-11-2016 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 AUP74_RS12405 6ca0cb8da462aafe9e278275abf2f433 701 SMART SM00228 246 324 1.5E-8 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS12405 6ca0cb8da462aafe9e278275abf2f433 701 Gene3D G3DSA:3.90.226.10 336 538 5.5E-62 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS12405 6ca0cb8da462aafe9e278275abf2f433 701 Gene3D G3DSA:3.90.226.10 663 684 5.5E-62 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS12405 6ca0cb8da462aafe9e278275abf2f433 701 SUPERFAMILY SSF52096 182 264 3.64E-68 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS12405 6ca0cb8da462aafe9e278275abf2f433 701 SUPERFAMILY SSF52096 351 544 3.64E-68 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS12405 6ca0cb8da462aafe9e278275abf2f433 701 SMART SM00245 327 536 4.8E-56 T 11-11-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 AUP74_RS12405 6ca0cb8da462aafe9e278275abf2f433 701 Gene3D G3DSA:3.30.750.44 199 251 1.4E-5 T 11-11-2016 AUP74_RS12405 6ca0cb8da462aafe9e278275abf2f433 701 SUPERFAMILY SSF50156 245 320 3.11E-11 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS12405 6ca0cb8da462aafe9e278275abf2f433 701 Gene3D G3DSA:2.30.42.10 252 335 4.0E-18 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS12405 6ca0cb8da462aafe9e278275abf2f433 701 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 239 319 1.1E-10 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS16365 8216727c7eba6651db101c31bb210ab7 810 Gene3D G3DSA:1.20.1260.10 61 217 2.7E-47 T 11-11-2016 IPR012347 Ferritin-related AUP74_RS16365 8216727c7eba6651db101c31bb210ab7 810 Pfam PF03713 Domain of unknown function (DUF305) 65 215 3.2E-43 T 11-11-2016 IPR005183 Domain of unknown function DUF305 AUP74_RS16365 8216727c7eba6651db101c31bb210ab7 810 SUPERFAMILY SSF82171 293 332 7.45E-7 T 11-11-2016 AUP74_RS16365 8216727c7eba6651db101c31bb210ab7 810 SUPERFAMILY SSF82171 372 419 7.45E-7 T 11-11-2016 AUP74_RS16365 8216727c7eba6651db101c31bb210ab7 810 SUPERFAMILY SSF82171 446 566 7.45E-7 T 11-11-2016 AUP74_RS12720 1e19115625e8088eca70c25dc2027d02 91 Pfam PF09527 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter 37 86 2.7E-10 T 11-11-2016 IPR032820 Putative F0F1-ATPase subunit, Ca2+/Mg2+ transporter AUP74_RS13725 1ef2a3c036f1f936c468d30babde8a81 416 Gene3D G3DSA:3.40.50.150 131 408 3.9E-97 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS13725 1ef2a3c036f1f936c468d30babde8a81 416 SUPERFAMILY SSF53335 19 361 2.69E-86 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS13725 1ef2a3c036f1f936c468d30babde8a81 416 Pfam PF02353 Mycolic acid cyclopropane synthetase 136 404 2.3E-89 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS13725 1ef2a3c036f1f936c468d30babde8a81 416 PIRSF PIRSF003085 14 415 1.6E-126 T 11-11-2016 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 AUP74_RS13240 fc84c0055a2d96219ca6093f229ebcbd 851 Pfam PF00271 Helicase conserved C-terminal domain 214 334 7.5E-14 T 11-11-2016 IPR001650 Helicase, C-terminal AUP74_RS13240 fc84c0055a2d96219ca6093f229ebcbd 851 Gene3D G3DSA:3.40.50.300 3 161 4.4E-46 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS13240 fc84c0055a2d96219ca6093f229ebcbd 851 SMART SM00490 235 335 1.4E-18 T 11-11-2016 IPR001650 Helicase, C-terminal AUP74_RS13240 fc84c0055a2d96219ca6093f229ebcbd 851 Pfam PF04408 Helicase associated domain (HA2) 397 476 2.2E-13 T 11-11-2016 IPR007502 Helicase-associated domain GO:0004386 AUP74_RS13240 fc84c0055a2d96219ca6093f229ebcbd 851 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 4 847 0.0 T 11-11-2016 IPR010225 RNA helicase, ATP-dependent DEAH box, HrpB-type AUP74_RS13240 fc84c0055a2d96219ca6093f229ebcbd 851 Pfam PF00270 DEAD/DEAH box helicase 14 166 1.1E-12 T 11-11-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AUP74_RS13240 fc84c0055a2d96219ca6093f229ebcbd 851 SUPERFAMILY SSF52540 16 346 8.56E-53 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS13240 fc84c0055a2d96219ca6093f229ebcbd 851 SMART SM00487 2 187 8.7E-24 T 11-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain AUP74_RS13240 fc84c0055a2d96219ca6093f229ebcbd 851 Pfam PF08482 ATP-dependent helicase C-terminal 704 835 5.5E-52 T 11-11-2016 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal AUP74_RS13240 fc84c0055a2d96219ca6093f229ebcbd 851 PIRSF PIRSF005496 1 849 0.0 T 11-11-2016 IPR010225 RNA helicase, ATP-dependent DEAH box, HrpB-type AUP74_RS13240 fc84c0055a2d96219ca6093f229ebcbd 851 SMART SM00847 395 491 2.9E-10 T 11-11-2016 IPR007502 Helicase-associated domain GO:0004386 AUP74_RS13240 fc84c0055a2d96219ca6093f229ebcbd 851 Gene3D G3DSA:3.40.50.300 208 351 6.7E-15 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS07825 698e9832fda3be8967f825614703ad08 1021 Gene3D G3DSA:1.10.1060.10 656 704 2.1E-15 T 11-11-2016 AUP74_RS07825 698e9832fda3be8967f825614703ad08 1021 Gene3D G3DSA:1.10.1060.10 515 618 2.1E-15 T 11-11-2016 AUP74_RS07825 698e9832fda3be8967f825614703ad08 1021 SUPERFAMILY SSF55103 259 540 1.18E-49 T 11-11-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 AUP74_RS07825 698e9832fda3be8967f825614703ad08 1021 Gene3D G3DSA:3.30.465.10 110 284 1.1E-39 T 11-11-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 AUP74_RS07825 698e9832fda3be8967f825614703ad08 1021 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 671 682 - T 11-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AUP74_RS07825 698e9832fda3be8967f825614703ad08 1021 Pfam PF01565 FAD binding domain 52 189 8.7E-35 T 11-11-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AUP74_RS07825 698e9832fda3be8967f825614703ad08 1021 Pfam PF13183 4Fe-4S dicluster domain 576 685 2.1E-12 T 11-11-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AUP74_RS07825 698e9832fda3be8967f825614703ad08 1021 SUPERFAMILY SSF46548 560 621 1.45E-7 T 11-11-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 AUP74_RS07825 698e9832fda3be8967f825614703ad08 1021 SUPERFAMILY SSF46548 652 689 1.45E-7 T 11-11-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 AUP74_RS07825 698e9832fda3be8967f825614703ad08 1021 SUPERFAMILY SSF56176 16 192 3.31E-49 T 11-11-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 AUP74_RS07825 698e9832fda3be8967f825614703ad08 1021 SUPERFAMILY SSF56176 252 284 3.31E-49 T 11-11-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 AUP74_RS07825 698e9832fda3be8967f825614703ad08 1021 Gene3D G3DSA:3.30.43.10 9 109 6.3E-22 T 11-11-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 AUP74_RS07825 698e9832fda3be8967f825614703ad08 1021 Pfam PF02913 FAD linked oxidases, C-terminal domain 284 538 7.8E-58 T 11-11-2016 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 AUP74_RS15825 df56534821e522a64b6eb057f0ac7639 748 Gene3D G3DSA:2.40.170.20 177 747 7.8E-74 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS15825 df56534821e522a64b6eb057f0ac7639 748 Pfam PF00593 TonB dependent receptor 482 746 7.7E-17 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS15825 df56534821e522a64b6eb057f0ac7639 748 SUPERFAMILY SSF56935 34 746 1.79E-100 T 11-11-2016 AUP74_RS15825 df56534821e522a64b6eb057f0ac7639 748 Gene3D G3DSA:2.170.130.10 41 176 1.3E-26 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS15825 df56534821e522a64b6eb057f0ac7639 748 Pfam PF07715 TonB-dependent Receptor Plug Domain 58 167 6.8E-13 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS12575 bb82dec75a16baefe85c324400225e2e 589 SUPERFAMILY SSF51338 22 82 5.04E-17 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS12575 bb82dec75a16baefe85c324400225e2e 589 SUPERFAMILY SSF51338 518 559 5.04E-17 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS12575 bb82dec75a16baefe85c324400225e2e 589 Pfam PF07969 Amidohydrolase family 70 557 1.8E-105 T 11-11-2016 IPR013108 Amidohydrolase 3 AUP74_RS12575 bb82dec75a16baefe85c324400225e2e 589 SUPERFAMILY SSF51556 81 139 4.82E-39 T 11-11-2016 IPR032466 Metal-dependent hydrolase AUP74_RS12575 bb82dec75a16baefe85c324400225e2e 589 SUPERFAMILY SSF51556 219 518 4.82E-39 T 11-11-2016 IPR032466 Metal-dependent hydrolase AUP74_RS12575 bb82dec75a16baefe85c324400225e2e 589 Gene3D G3DSA:3.20.20.140 224 503 8.6E-20 T 11-11-2016 AUP74_RS12575 bb82dec75a16baefe85c324400225e2e 589 Gene3D G3DSA:2.30.40.10 20 95 5.9E-12 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS12575 bb82dec75a16baefe85c324400225e2e 589 Gene3D G3DSA:3.20.20.140 504 557 9.8E-6 T 11-11-2016 AUP74_RS06320 2771a6cb5ddea2ca9d4de8b1aa19314c 148 Gene3D G3DSA:1.10.1510.10 3 91 1.4E-32 T 11-11-2016 AUP74_RS06320 2771a6cb5ddea2ca9d4de8b1aa19314c 148 SUPERFAMILY SSF89095 3 147 2.46E-44 T 11-11-2016 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 AUP74_RS06320 2771a6cb5ddea2ca9d4de8b1aa19314c 148 Gene3D G3DSA:1.10.10.410 92 147 1.9E-24 T 11-11-2016 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal AUP74_RS06320 2771a6cb5ddea2ca9d4de8b1aa19314c 148 Pfam PF09424 Yqey-like protein 5 147 7.8E-56 T 11-11-2016 IPR019004 Uncharacterised domain YOR215C, mitochondrial AUP74_RS13340 a4acdc65ec3602ffef65ccf6f376fab4 1048 Gene3D G3DSA:3.30.2090.10 195 271 6.2E-14 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS13340 a4acdc65ec3602ffef65ccf6f376fab4 1048 SUPERFAMILY SSF82866 807 1031 4.58E-44 T 11-11-2016 AUP74_RS13340 a4acdc65ec3602ffef65ccf6f376fab4 1048 SUPERFAMILY SSF82714 731 807 1.1E-8 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS13340 a4acdc65ec3602ffef65ccf6f376fab4 1048 Gene3D G3DSA:3.30.2090.10 731 807 3.3E-8 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS13340 a4acdc65ec3602ffef65ccf6f376fab4 1048 Gene3D G3DSA:3.30.70.1430 60 150 1.3E-21 T 11-11-2016 AUP74_RS13340 a4acdc65ec3602ffef65ccf6f376fab4 1048 Gene3D G3DSA:1.10.3850.10 813 1031 8.4E-55 T 11-11-2016 AUP74_RS13340 a4acdc65ec3602ffef65ccf6f376fab4 1048 Gene3D G3DSA:3.30.70.1320 272 319 1.6E-6 T 11-11-2016 AUP74_RS13340 a4acdc65ec3602ffef65ccf6f376fab4 1048 PRINTS PR00702 Acriflavin resistance protein family signature 451 474 1.8E-22 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS13340 a4acdc65ec3602ffef65ccf6f376fab4 1048 PRINTS PR00702 Acriflavin resistance protein family signature 476 499 1.8E-22 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS13340 a4acdc65ec3602ffef65ccf6f376fab4 1048 PRINTS PR00702 Acriflavin resistance protein family signature 398 422 1.8E-22 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS13340 a4acdc65ec3602ffef65ccf6f376fab4 1048 PRINTS PR00702 Acriflavin resistance protein family signature 370 391 1.8E-22 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS13340 a4acdc65ec3602ffef65ccf6f376fab4 1048 PRINTS PR00702 Acriflavin resistance protein family signature 56 74 1.8E-22 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS13340 a4acdc65ec3602ffef65ccf6f376fab4 1048 SUPERFAMILY SSF82714 196 278 3.92E-14 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS13340 a4acdc65ec3602ffef65ccf6f376fab4 1048 SUPERFAMILY SSF82866 309 502 9.94E-40 T 11-11-2016 AUP74_RS13340 a4acdc65ec3602ffef65ccf6f376fab4 1048 SUPERFAMILY SSF82693 59 147 1.1E-19 T 11-11-2016 AUP74_RS13340 a4acdc65ec3602ffef65ccf6f376fab4 1048 Gene3D G3DSA:1.20.1640.10 320 509 2.6E-44 T 11-11-2016 AUP74_RS13340 a4acdc65ec3602ffef65ccf6f376fab4 1048 Pfam PF00873 AcrB/AcrD/AcrF family 28 1029 1.3E-167 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS13340 a4acdc65ec3602ffef65ccf6f376fab4 1048 SUPERFAMILY SSF82693 160 195 8.63E-9 T 11-11-2016 AUP74_RS13340 a4acdc65ec3602ffef65ccf6f376fab4 1048 SUPERFAMILY SSF82693 282 338 8.63E-9 T 11-11-2016 AUP74_RS15855 165c84f5d310fb500ac50a3b6c60c10f 399 Pfam PF00155 Aminotransferase class I and II 46 388 1.3E-74 T 11-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AUP74_RS15855 165c84f5d310fb500ac50a3b6c60c10f 399 TIGRFAM TIGR01822 2am3keto_CoA: glycine C-acetyltransferase 8 399 2.2E-214 T 11-11-2016 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|Reactome: R-HSA-8849175 AUP74_RS15855 165c84f5d310fb500ac50a3b6c60c10f 399 SUPERFAMILY SSF53383 5 397 1.21E-125 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase AUP74_RS15855 165c84f5d310fb500ac50a3b6c60c10f 399 Hamap MF_00985 2-amino-3-ketobutyrate coenzyme A ligase [kbl]. 4 397 54.972 T 11-11-2016 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|Reactome: R-HSA-8849175 AUP74_RS15855 165c84f5d310fb500ac50a3b6c60c10f 399 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 243 252 - T 11-11-2016 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 AUP74_RS15855 165c84f5d310fb500ac50a3b6c60c10f 399 Gene3D G3DSA:3.90.1150.10 281 395 6.7E-38 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS15855 165c84f5d310fb500ac50a3b6c60c10f 399 Gene3D G3DSA:3.40.640.10 63 280 3.2E-89 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AUP74_RS08280 6a87cdb62da31c472ed27de58cd9f00b 295 Gene3D G3DSA:3.40.50.620 166 282 2.6E-16 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS08280 6a87cdb62da31c472ed27de58cd9f00b 295 Gene3D G3DSA:3.40.50.620 7 156 8.1E-38 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS08280 6a87cdb62da31c472ed27de58cd9f00b 295 Hamap MF_01428 Glutamyl-Q tRNA(Asp) synthetase [gluQ]. 9 294 38.163 T 11-11-2016 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 AUP74_RS08280 6a87cdb62da31c472ed27de58cd9f00b 295 TIGRFAM TIGR03838 queuosine_YadB: glutamyl-queuosine tRNA(Asp) synthetase 9 273 8.8E-103 T 11-11-2016 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 AUP74_RS08280 6a87cdb62da31c472ed27de58cd9f00b 295 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 12 241 1.4E-38 T 11-11-2016 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 AUP74_RS08280 6a87cdb62da31c472ed27de58cd9f00b 295 SUPERFAMILY SSF52374 9 289 3.1E-79 T 11-11-2016 AUP74_RS08280 6a87cdb62da31c472ed27de58cd9f00b 295 PRINTS PR00987 Glutamyl-tRNA synthetase signature 41 54 3.1E-13 T 11-11-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 AUP74_RS08280 6a87cdb62da31c472ed27de58cd9f00b 295 PRINTS PR00987 Glutamyl-tRNA synthetase signature 12 24 3.1E-13 T 11-11-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 AUP74_RS08280 6a87cdb62da31c472ed27de58cd9f00b 295 PRINTS PR00987 Glutamyl-tRNA synthetase signature 174 184 3.1E-13 T 11-11-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 AUP74_RS08280 6a87cdb62da31c472ed27de58cd9f00b 295 PRINTS PR00987 Glutamyl-tRNA synthetase signature 190 198 3.1E-13 T 11-11-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 AUP74_RS01915 f01a3acc5fa374cec4832e1ff2fa3138 123 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 112 5.9E-5 T 11-11-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AUP74_RS01915 f01a3acc5fa374cec4832e1ff2fa3138 123 SUPERFAMILY SSF54593 8 116 2.15E-20 T 11-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AUP74_RS01915 f01a3acc5fa374cec4832e1ff2fa3138 123 Gene3D G3DSA:3.10.180.10 10 119 7.1E-19 T 11-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AUP74_RS07700 54c4841e17fb7fc0126fbcdb4b92bceb 237 Hamap MF_00478 Electron transport complex subunit RsxE [rsxE]. 6 213 26.816 T 11-11-2016 IPR010968 Electron transport complex, RsxE GO:0016020|GO:0022900 AUP74_RS07700 54c4841e17fb7fc0126fbcdb4b92bceb 237 Pfam PF02508 Rnf-Nqr subunit, membrane protein 9 203 2.7E-64 T 11-11-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 AUP74_RS07700 54c4841e17fb7fc0126fbcdb4b92bceb 237 TIGRFAM TIGR01948 rnfE: electron transport complex, RnfABCDGE type, E subunit 9 210 2.8E-82 T 11-11-2016 IPR010968 Electron transport complex, RsxE GO:0016020|GO:0022900 AUP74_RS07700 54c4841e17fb7fc0126fbcdb4b92bceb 237 PIRSF PIRSF006102 3 222 2.0E-74 T 11-11-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 AUP74_RS06155 3d7364a093f88e9684bc2b208726ccdd 231 SUPERFAMILY SSF53271 50 230 2.1E-33 T 11-11-2016 IPR029057 Phosphoribosyltransferase-like AUP74_RS06155 3d7364a093f88e9684bc2b208726ccdd 231 Pfam PF00156 Phosphoribosyl transferase domain 178 229 5.5E-7 T 11-11-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 AUP74_RS06155 3d7364a093f88e9684bc2b208726ccdd 231 Gene3D G3DSA:3.40.50.2020 59 231 2.6E-31 T 11-11-2016 IPR029057 Phosphoribosyltransferase-like AUP74_RS04170 c0677c58c5a24bd20649936ed47bd143 258 Hamap MF_00652 UPF0246 protein YaaA [yaaA]. 1 255 37.017 T 11-11-2016 IPR005583 Peroxide stress protein YaaA AUP74_RS04170 c0677c58c5a24bd20649936ed47bd143 258 Pfam PF03883 Protein of unknown function (DUF328) 1 243 1.2E-90 T 11-11-2016 IPR005583 Peroxide stress protein YaaA AUP74_RS10335 98e55d1b9a31bd84aad4d1cedf72b42e 157 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 38 54 8.8E-11 T 11-11-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 AUP74_RS10335 98e55d1b9a31bd84aad4d1cedf72b42e 157 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 133 151 8.8E-11 T 11-11-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 AUP74_RS10335 98e55d1b9a31bd84aad4d1cedf72b42e 157 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 62 78 8.8E-11 T 11-11-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 AUP74_RS10335 98e55d1b9a31bd84aad4d1cedf72b42e 157 ProSitePatterns PS00819 Dps protein family signature 2. 64 78 - T 11-11-2016 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 AUP74_RS10335 98e55d1b9a31bd84aad4d1cedf72b42e 157 PIRSF PIRSF005900 1 157 3.0E-48 T 11-11-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 AUP74_RS10335 98e55d1b9a31bd84aad4d1cedf72b42e 157 Pfam PF00210 Ferritin-like domain 18 153 2.0E-29 T 11-11-2016 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 AUP74_RS10335 98e55d1b9a31bd84aad4d1cedf72b42e 157 ProSitePatterns PS00818 Dps protein family signature 1. 38 54 - T 11-11-2016 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 AUP74_RS10335 98e55d1b9a31bd84aad4d1cedf72b42e 157 SUPERFAMILY SSF47240 4 154 2.39E-45 T 11-11-2016 IPR009078 Ferritin-like superfamily AUP74_RS10335 98e55d1b9a31bd84aad4d1cedf72b42e 157 Gene3D G3DSA:1.20.1260.10 1 154 4.4E-61 T 11-11-2016 IPR012347 Ferritin-related AUP74_RS12790 4c228648c15805605a8fe1b358142f25 448 Gene3D G3DSA:1.10.3710.10 345 441 8.8E-32 T 11-11-2016 AUP74_RS12790 4c228648c15805605a8fe1b358142f25 448 SUPERFAMILY SSF48019 249 431 1.7E-72 T 11-11-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 AUP74_RS12790 4c228648c15805605a8fe1b358142f25 448 SMART SM00382 47 164 1.5E-15 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS12790 4c228648c15805605a8fe1b358142f25 448 Gene3D G3DSA:3.40.50.300 8 152 8.2E-33 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS12790 4c228648c15805605a8fe1b358142f25 448 Gene3D G3DSA:1.20.272.10 246 344 1.4E-42 T 11-11-2016 AUP74_RS12790 4c228648c15805605a8fe1b358142f25 448 Pfam PF12002 MgsA AAA+ ATPase C terminal 265 431 3.8E-66 T 11-11-2016 IPR021886 MgsA AAA+ ATPase C-terminal AUP74_RS12790 4c228648c15805605a8fe1b358142f25 448 SUPERFAMILY SSF52540 8 238 1.8E-51 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS12790 4c228648c15805605a8fe1b358142f25 448 Pfam PF16193 AAA C-terminal domain 188 264 7.3E-22 T 11-11-2016 IPR032423 AAA ATPase, C-terminal domain AUP74_RS12790 4c228648c15805605a8fe1b358142f25 448 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 51 160 2.1E-15 T 11-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 AUP74_RS12790 4c228648c15805605a8fe1b358142f25 448 Gene3D G3DSA:1.10.8.60 153 223 1.9E-13 T 11-11-2016 AUP74_RS11120 be9738c1a898f008e5993664a3f4b493 456 PIRSF PIRSF019381 1 456 1.9E-109 T 11-11-2016 IPR007413 Protein of unknown function DUF463, YcjX-like protein AUP74_RS11120 be9738c1a898f008e5993664a3f4b493 456 Gene3D G3DSA:3.40.50.300 196 291 5.8E-8 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11120 be9738c1a898f008e5993664a3f4b493 456 Gene3D G3DSA:3.40.50.300 151 160 5.8E-8 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11120 be9738c1a898f008e5993664a3f4b493 456 Gene3D G3DSA:3.40.50.300 90 133 7.7E-4 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11120 be9738c1a898f008e5993664a3f4b493 456 Pfam PF04317 YcjX-like family, DUF463 23 455 7.7E-115 T 11-11-2016 IPR007413 Protein of unknown function DUF463, YcjX-like protein AUP74_RS11120 be9738c1a898f008e5993664a3f4b493 456 Gene3D G3DSA:3.40.50.300 16 78 1.2E-4 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11120 be9738c1a898f008e5993664a3f4b493 456 SUPERFAMILY SSF52540 186 266 2.92E-5 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11120 be9738c1a898f008e5993664a3f4b493 456 SUPERFAMILY SSF52540 22 90 2.92E-5 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS13300 ccaf04553f2cdebca816364266ebf186 196 Pfam PF06723 MreB/Mbl protein 22 143 2.0E-6 T 11-11-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 AUP74_RS11205 1a811e95fc14f2bcbb4e6680963ca6d1 212 PRINTS PR00127 Clp protease catalytic subunit P signature 33 48 7.6E-54 T 11-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AUP74_RS11205 1a811e95fc14f2bcbb4e6680963ca6d1 212 PRINTS PR00127 Clp protease catalytic subunit P signature 104 121 7.6E-54 T 11-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AUP74_RS11205 1a811e95fc14f2bcbb4e6680963ca6d1 212 PRINTS PR00127 Clp protease catalytic subunit P signature 125 144 7.6E-54 T 11-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AUP74_RS11205 1a811e95fc14f2bcbb4e6680963ca6d1 212 PRINTS PR00127 Clp protease catalytic subunit P signature 182 201 7.6E-54 T 11-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AUP74_RS11205 1a811e95fc14f2bcbb4e6680963ca6d1 212 PRINTS PR00127 Clp protease catalytic subunit P signature 73 93 7.6E-54 T 11-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AUP74_RS11205 1a811e95fc14f2bcbb4e6680963ca6d1 212 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 16 206 1.6E-105 T 11-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AUP74_RS11205 1a811e95fc14f2bcbb4e6680963ca6d1 212 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 104 115 - T 11-11-2016 IPR018215 ClpP, Ser active site AUP74_RS11205 1a811e95fc14f2bcbb4e6680963ca6d1 212 SUPERFAMILY SSF52096 25 210 1.14E-74 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS11205 1a811e95fc14f2bcbb4e6680963ca6d1 212 Pfam PF00574 Clp protease 27 206 3.4E-88 T 11-11-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA AUP74_RS11205 1a811e95fc14f2bcbb4e6680963ca6d1 212 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 17 207 44.088 T 11-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AUP74_RS11205 1a811e95fc14f2bcbb4e6680963ca6d1 212 Gene3D G3DSA:3.90.226.10 17 207 2.9E-92 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS11205 1a811e95fc14f2bcbb4e6680963ca6d1 212 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 126 139 - T 11-11-2016 IPR033135 ClpP, histidine active site AUP74_RS13985 48cf2782324e580dadb42c0cbe73bf8b 263 SUPERFAMILY SSF53697 103 259 2.22E-16 T 11-11-2016 AUP74_RS13985 48cf2782324e580dadb42c0cbe73bf8b 263 Gene3D G3DSA:3.40.50.10490 103 261 6.0E-18 T 11-11-2016 AUP74_RS13985 48cf2782324e580dadb42c0cbe73bf8b 263 Gene3D G3DSA:1.10.10.10 1 76 5.3E-22 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS13985 48cf2782324e580dadb42c0cbe73bf8b 263 Pfam PF01418 Helix-turn-helix domain, rpiR family 1 76 3.2E-21 T 11-11-2016 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 AUP74_RS13985 48cf2782324e580dadb42c0cbe73bf8b 263 Pfam PF01380 SIS domain 128 234 4.2E-9 T 11-11-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 AUP74_RS13985 48cf2782324e580dadb42c0cbe73bf8b 263 SUPERFAMILY SSF46689 1 76 2.69E-17 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS07205 d54352314aa95c348055be78049b1b23 164 SUPERFAMILY SSF82153 16 162 4.58E-42 T 11-11-2016 IPR000782 FAS1 domain AUP74_RS07205 d54352314aa95c348055be78049b1b23 164 Gene3D G3DSA:2.30.180.10 16 161 8.1E-41 T 11-11-2016 IPR000782 FAS1 domain AUP74_RS07205 d54352314aa95c348055be78049b1b23 164 SMART SM00554 51 162 8.1E-30 T 11-11-2016 IPR000782 FAS1 domain AUP74_RS07205 d54352314aa95c348055be78049b1b23 164 Pfam PF02469 Fasciclin domain 27 161 9.8E-35 T 11-11-2016 IPR000782 FAS1 domain AUP74_RS08405 62e178fc72fdeac7a094062714c21dfb 297 SUPERFAMILY SSF55486 68 230 6.81E-7 T 11-11-2016 AUP74_RS08405 62e178fc72fdeac7a094062714c21dfb 297 Pfam PF04228 Putative neutral zinc metallopeptidase 1 291 7.0E-113 T 11-11-2016 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative AUP74_RS11940 afb455246de3c84d0fce22322e979c3c 407 Gene3D G3DSA:2.40.30.10 128 264 4.8E-59 T 11-11-2016 AUP74_RS11940 afb455246de3c84d0fce22322e979c3c 407 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 40 115 3.5E-10 T 11-11-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AUP74_RS11940 afb455246de3c84d0fce22322e979c3c 407 Pfam PF00970 Oxidoreductase FAD-binding domain 201 266 1.2E-10 T 11-11-2016 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 AUP74_RS11940 afb455246de3c84d0fce22322e979c3c 407 SUPERFAMILY SSF52343 257 402 4.71E-37 T 11-11-2016 AUP74_RS11940 afb455246de3c84d0fce22322e979c3c 407 Gene3D G3DSA:3.10.20.30 42 127 1.9E-20 T 11-11-2016 IPR012675 Beta-grasp domain AUP74_RS11940 afb455246de3c84d0fce22322e979c3c 407 PIRSF PIRSF000044 1 407 2.7E-222 T 11-11-2016 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 AUP74_RS11940 afb455246de3c84d0fce22322e979c3c 407 SUPERFAMILY SSF54292 38 124 1.26E-22 T 11-11-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AUP74_RS11940 afb455246de3c84d0fce22322e979c3c 407 Gene3D G3DSA:3.40.50.80 269 406 3.8E-41 T 11-11-2016 AUP74_RS11940 afb455246de3c84d0fce22322e979c3c 407 Pfam PF00175 Oxidoreductase NAD-binding domain 277 385 2.4E-16 T 11-11-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AUP74_RS11940 afb455246de3c84d0fce22322e979c3c 407 TIGRFAM TIGR01941 nqrF: NADH:ubiquinone oxidoreductase, Na(+)-translocating, F subunit 5 407 6.0E-221 T 11-11-2016 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 AUP74_RS11940 afb455246de3c84d0fce22322e979c3c 407 SUPERFAMILY SSF63380 106 272 1.13E-36 T 11-11-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 AUP74_RS11940 afb455246de3c84d0fce22322e979c3c 407 Hamap MF_00430 Na(+)-translocating NADH-quinone reductase subunit F [nqrF]. 3 407 63.838 T 11-11-2016 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 AUP74_RS02080 bcefcb42fd02d4cbd8495cd516086c72 931 Gene3D G3DSA:2.170.130.10 40 161 9.2E-18 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS02080 bcefcb42fd02d4cbd8495cd516086c72 931 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 38 930 2.7E-162 T 11-11-2016 IPR010104 Bacterial TonB-dependent receptor AUP74_RS02080 bcefcb42fd02d4cbd8495cd516086c72 931 Pfam PF00593 TonB dependent receptor 634 929 1.6E-19 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS02080 bcefcb42fd02d4cbd8495cd516086c72 931 Gene3D G3DSA:2.40.170.20 453 523 1.4E-54 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS02080 bcefcb42fd02d4cbd8495cd516086c72 931 Gene3D G3DSA:2.40.170.20 162 380 1.4E-54 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS02080 bcefcb42fd02d4cbd8495cd516086c72 931 Gene3D G3DSA:2.40.170.20 567 929 1.4E-54 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS02080 bcefcb42fd02d4cbd8495cd516086c72 931 Pfam PF07715 TonB-dependent Receptor Plug Domain 57 161 1.8E-14 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS02080 bcefcb42fd02d4cbd8495cd516086c72 931 SUPERFAMILY SSF56935 692 930 3.05E-80 T 11-11-2016 AUP74_RS02080 bcefcb42fd02d4cbd8495cd516086c72 931 SUPERFAMILY SSF56935 263 397 3.05E-80 T 11-11-2016 AUP74_RS02080 bcefcb42fd02d4cbd8495cd516086c72 931 SUPERFAMILY SSF56935 442 504 3.05E-80 T 11-11-2016 AUP74_RS02080 bcefcb42fd02d4cbd8495cd516086c72 931 SUPERFAMILY SSF56935 31 233 3.05E-80 T 11-11-2016 AUP74_RS02080 bcefcb42fd02d4cbd8495cd516086c72 931 SUPERFAMILY SSF56935 535 663 3.05E-80 T 11-11-2016 AUP74_RS01050 f84e813f1ca8ffcdca93d5c71a0e368c 806 SUPERFAMILY SSF103647 309 369 4.71E-6 T 11-11-2016 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 AUP74_RS01050 f84e813f1ca8ffcdca93d5c71a0e368c 806 Gene3D G3DSA:4.10.1080.10 266 369 9.1E-19 T 11-11-2016 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 AUP74_RS01050 f84e813f1ca8ffcdca93d5c71a0e368c 806 Gene3D G3DSA:4.10.1080.10 200 265 4.6E-8 T 11-11-2016 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 AUP74_RS01050 f84e813f1ca8ffcdca93d5c71a0e368c 806 SUPERFAMILY SSF50939 530 796 5.89E-14 T 11-11-2016 IPR011040 Sialidases Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 AUP74_RS01565 0bee8886b0500d4e0b06129e7a45d6d9 156 Pfam PF03477 ATP cone domain 50 136 1.9E-16 T 11-11-2016 IPR005144 ATP-cone domain Reactome: R-HSA-499943 AUP74_RS01565 0bee8886b0500d4e0b06129e7a45d6d9 156 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 147 1.2E-69 T 11-11-2016 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 AUP74_RS01565 0bee8886b0500d4e0b06129e7a45d6d9 156 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 153 88.399 T 11-11-2016 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 AUP74_RS01870 9039200fcb19f18b9c8b764055d544a0 752 Pfam PF02769 AIR synthase related protein, C-terminal domain 558 733 1.1E-20 T 11-11-2016 IPR010918 AIR synthase-related protein, C-terminal domain AUP74_RS01870 9039200fcb19f18b9c8b764055d544a0 752 SUPERFAMILY SSF51905 5 201 7.99E-19 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS01870 9039200fcb19f18b9c8b764055d544a0 752 SUPERFAMILY SSF51905 156 321 9.86E-24 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS01870 9039200fcb19f18b9c8b764055d544a0 752 Gene3D G3DSA:3.90.650.10 563 733 2.1E-11 T 11-11-2016 IPR010918 AIR synthase-related protein, C-terminal domain AUP74_RS01870 9039200fcb19f18b9c8b764055d544a0 752 Pfam PF00586 AIR synthase related protein, N-terminal domain 437 545 3.6E-11 T 11-11-2016 IPR016188 PurM-like, N-terminal domain AUP74_RS01870 9039200fcb19f18b9c8b764055d544a0 752 SUPERFAMILY SSF56042 554 729 9.59E-39 T 11-11-2016 IPR010918 AIR synthase-related protein, C-terminal domain AUP74_RS01870 9039200fcb19f18b9c8b764055d544a0 752 Gene3D G3DSA:3.30.1330.10 424 548 8.3E-20 T 11-11-2016 IPR016188 PurM-like, N-terminal domain AUP74_RS01870 9039200fcb19f18b9c8b764055d544a0 752 Gene3D G3DSA:3.50.50.60 137 315 9.1E-27 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS01870 9039200fcb19f18b9c8b764055d544a0 752 SUPERFAMILY SSF55326 401 549 4.36E-29 T 11-11-2016 AUP74_RS01870 9039200fcb19f18b9c8b764055d544a0 752 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 308 8.2E-28 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS01870 9039200fcb19f18b9c8b764055d544a0 752 TIGRFAM TIGR00476 selD: selenide, water dikinase 403 706 1.1E-78 T 11-11-2016 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 AUP74_RS01870 9039200fcb19f18b9c8b764055d544a0 752 Gene3D G3DSA:3.50.50.60 8 124 1.7E-10 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS01870 9039200fcb19f18b9c8b764055d544a0 752 TIGRFAM TIGR03169 Nterm_to_SelD: pyridine nucleotide-disulfide oxidoreductase family protein 9 373 1.0E-141 T 11-11-2016 IPR017584 Pyridine nucleotide-disulphide oxidoreductase family protein, N-terminal AUP74_RS07630 d156341517b02a18f64d0d94ec735bdb 696 Gene3D G3DSA:3.90.1580.10 435 693 8.4E-53 T 11-11-2016 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 AUP74_RS07630 d156341517b02a18f64d0d94ec735bdb 696 Gene3D G3DSA:2.60.40.1120 94 135 7.9E-4 T 11-11-2016 IPR014766 Carboxypeptidase, regulatory domain AUP74_RS07630 d156341517b02a18f64d0d94ec735bdb 696 Pfam PF03781 Sulfatase-modifying factor enzyme 1 441 693 9.8E-48 T 11-11-2016 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 AUP74_RS07630 d156341517b02a18f64d0d94ec735bdb 696 Pfam PF08308 PEGA domain 276 341 1.3E-13 T 11-11-2016 IPR013229 PEGA AUP74_RS07630 d156341517b02a18f64d0d94ec735bdb 696 Pfam PF08308 PEGA domain 205 263 1.9E-11 T 11-11-2016 IPR013229 PEGA AUP74_RS07630 d156341517b02a18f64d0d94ec735bdb 696 Pfam PF08308 PEGA domain 346 409 1.4E-12 T 11-11-2016 IPR013229 PEGA AUP74_RS07630 d156341517b02a18f64d0d94ec735bdb 696 SUPERFAMILY SSF56436 437 693 3.3E-51 T 11-11-2016 IPR016187 C-type lectin fold AUP74_RS16175 a2bf926d52527f41762d0f5f0774a365 344 Gene3D G3DSA:3.40.50.720 3 189 6.9E-63 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS16175 a2bf926d52527f41762d0f5f0774a365 344 SUPERFAMILY SSF48179 185 332 1.29E-51 T 11-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AUP74_RS16175 a2bf926d52527f41762d0f5f0774a365 344 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 10 328 35.45 T 11-11-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 AUP74_RS16175 a2bf926d52527f41762d0f5f0774a365 344 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 186 326 7.3E-48 T 11-11-2016 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 AUP74_RS16175 a2bf926d52527f41762d0f5f0774a365 344 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 11 166 2.4E-48 T 11-11-2016 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 AUP74_RS16175 a2bf926d52527f41762d0f5f0774a365 344 PIRSF PIRSF000114 5 337 3.2E-105 T 11-11-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 AUP74_RS16175 a2bf926d52527f41762d0f5f0774a365 344 SUPERFAMILY SSF51735 10 186 3.21E-50 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS16175 a2bf926d52527f41762d0f5f0774a365 344 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 14 31 1.2E-40 T 11-11-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 AUP74_RS16175 a2bf926d52527f41762d0f5f0774a365 344 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 204 228 1.2E-40 T 11-11-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 AUP74_RS16175 a2bf926d52527f41762d0f5f0774a365 344 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 139 159 1.2E-40 T 11-11-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 AUP74_RS16175 a2bf926d52527f41762d0f5f0774a365 344 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 244 261 1.2E-40 T 11-11-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 AUP74_RS16175 a2bf926d52527f41762d0f5f0774a365 344 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 179 203 1.2E-40 T 11-11-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 AUP74_RS16175 a2bf926d52527f41762d0f5f0774a365 344 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 64 91 1.2E-40 T 11-11-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 AUP74_RS16175 a2bf926d52527f41762d0f5f0774a365 344 Gene3D G3DSA:1.10.1040.10 190 331 3.3E-52 T 11-11-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AUP74_RS14655 5fded24a1302ecf47f56a8a89e38772b 288 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 221 4.0E-12 T 11-11-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 AUP74_RS14655 5fded24a1302ecf47f56a8a89e38772b 288 SUPERFAMILY SSF51735 1 245 7.82E-24 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS14655 5fded24a1302ecf47f56a8a89e38772b 288 Gene3D G3DSA:3.40.50.720 1 228 5.0E-21 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS10320 2cba16984932ccd9cb56ffd4017441cc 248 Pfam PF01925 Sulfite exporter TauE/SafE 15 241 1.2E-17 T 11-11-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 AUP74_RS06180 41097f2d125701db8898c3697bdddadf 227 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 2 212 28.499 T 11-11-2016 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 AUP74_RS06180 41097f2d125701db8898c3697bdddadf 227 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 6 177 3.3E-48 T 11-11-2016 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 AUP74_RS06180 41097f2d125701db8898c3697bdddadf 227 Pfam PF13500 AAA domain 3 211 5.4E-37 T 11-11-2016 AUP74_RS06180 41097f2d125701db8898c3697bdddadf 227 Gene3D G3DSA:3.40.50.300 3 213 3.2E-74 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS06180 41097f2d125701db8898c3697bdddadf 227 SUPERFAMILY SSF52540 3 216 6.76E-57 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS06180 41097f2d125701db8898c3697bdddadf 227 PIRSF PIRSF006755 1 222 1.1E-66 T 11-11-2016 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 AUP74_RS09850 574647a5551ea3675bfd8a41b82bb522 311 SUPERFAMILY SSF52402 3 141 7.95E-14 T 11-11-2016 AUP74_RS09850 574647a5551ea3675bfd8a41b82bb522 311 Gene3D G3DSA:3.40.50.620 137 303 3.6E-21 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS09850 574647a5551ea3675bfd8a41b82bb522 311 Gene3D G3DSA:3.40.50.620 1 136 4.3E-16 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS09850 574647a5551ea3675bfd8a41b82bb522 311 SUPERFAMILY SSF52402 152 309 1.17E-17 T 11-11-2016 AUP74_RS09850 574647a5551ea3675bfd8a41b82bb522 311 Pfam PF00582 Universal stress protein family 4 139 7.7E-10 T 11-11-2016 IPR006016 UspA GO:0006950 AUP74_RS09850 574647a5551ea3675bfd8a41b82bb522 311 Pfam PF00582 Universal stress protein family 152 301 1.1E-13 T 11-11-2016 IPR006016 UspA GO:0006950 AUP74_RS14395 55ee6b838be5cc125f8a4277c9986b36 283 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 166 194 - T 11-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AUP74_RS14395 55ee6b838be5cc125f8a4277c9986b36 283 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 104 115 3.8E-12 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS14395 55ee6b838be5cc125f8a4277c9986b36 283 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 179 198 3.8E-12 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS14395 55ee6b838be5cc125f8a4277c9986b36 283 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 167 3.8E-12 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS14395 55ee6b838be5cc125f8a4277c9986b36 283 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 279 1.4E-57 T 11-11-2016 AUP74_RS14395 55ee6b838be5cc125f8a4277c9986b36 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 244 264 5.2E-35 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS14395 55ee6b838be5cc125f8a4277c9986b36 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 198 5.2E-35 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS14395 55ee6b838be5cc125f8a4277c9986b36 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 200 217 5.2E-35 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS14395 55ee6b838be5cc125f8a4277c9986b36 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 104 115 5.2E-35 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS14395 55ee6b838be5cc125f8a4277c9986b36 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 5.2E-35 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS14395 55ee6b838be5cc125f8a4277c9986b36 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 169 5.2E-35 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS14395 55ee6b838be5cc125f8a4277c9986b36 283 Gene3D G3DSA:3.40.50.720 8 279 5.2E-82 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS14395 55ee6b838be5cc125f8a4277c9986b36 283 SUPERFAMILY SSF51735 12 279 2.52E-76 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS14900 1f64177c8c2185676688dc0da33d9a79 156 ProSitePatterns PS00519 AsnC-type HTH domain signature. 25 51 - T 11-11-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site AUP74_RS14900 1f64177c8c2185676688dc0da33d9a79 156 SMART SM00344 7 116 3.9E-42 T 11-11-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AUP74_RS14900 1f64177c8c2185676688dc0da33d9a79 156 SUPERFAMILY SSF46785 7 65 1.45E-17 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS14900 1f64177c8c2185676688dc0da33d9a79 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 2.6E-14 T 11-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 AUP74_RS14900 1f64177c8c2185676688dc0da33d9a79 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 2.6E-14 T 11-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 AUP74_RS14900 1f64177c8c2185676688dc0da33d9a79 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 2.6E-14 T 11-11-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 AUP74_RS14900 1f64177c8c2185676688dc0da33d9a79 156 Pfam PF13412 Winged helix-turn-helix DNA-binding 7 54 1.8E-19 T 11-11-2016 AUP74_RS14900 1f64177c8c2185676688dc0da33d9a79 156 Gene3D G3DSA:3.30.70.920 60 144 1.5E-28 T 11-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AUP74_RS14900 1f64177c8c2185676688dc0da33d9a79 156 Gene3D G3DSA:1.10.10.10 8 58 3.9E-24 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS14900 1f64177c8c2185676688dc0da33d9a79 156 SUPERFAMILY SSF54909 67 156 1.61E-20 T 11-11-2016 IPR011008 Dimeric alpha-beta barrel AUP74_RS14900 1f64177c8c2185676688dc0da33d9a79 156 Pfam PF01037 Lrp/AsnC ligand binding domain 75 147 5.8E-21 T 11-11-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AUP74_RS12700 ffbb82b718ea2aea01c3e4cdc44a4c2a 491 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 23 87 7.4E-5 T 11-11-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AUP74_RS12700 ffbb82b718ea2aea01c3e4cdc44a4c2a 491 Gene3D G3DSA:3.40.50.300 92 368 7.4E-86 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS12700 ffbb82b718ea2aea01c3e4cdc44a4c2a 491 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 4 468 2.7E-162 T 11-11-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 AUP74_RS12700 ffbb82b718ea2aea01c3e4cdc44a4c2a 491 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 368 465 1.7E-21 T 11-11-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AUP74_RS12700 ffbb82b718ea2aea01c3e4cdc44a4c2a 491 SUPERFAMILY SSF52540 94 367 2.3E-81 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS12700 ffbb82b718ea2aea01c3e4cdc44a4c2a 491 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 146 361 2.2E-59 T 11-11-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AUP74_RS12700 ffbb82b718ea2aea01c3e4cdc44a4c2a 491 Gene3D G3DSA:2.40.30.20 3 88 1.6E-18 T 11-11-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 AUP74_RS12700 ffbb82b718ea2aea01c3e4cdc44a4c2a 491 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 352 361 - T 11-11-2016 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AUP74_RS12700 ffbb82b718ea2aea01c3e4cdc44a4c2a 491 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 487 36.606 T 11-11-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 AUP74_RS12700 ffbb82b718ea2aea01c3e4cdc44a4c2a 491 SUPERFAMILY SSF47917 370 478 6.02E-24 T 11-11-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AUP74_RS12700 ffbb82b718ea2aea01c3e4cdc44a4c2a 491 SUPERFAMILY SSF50615 11 88 2.28E-17 T 11-11-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AUP74_RS12700 ffbb82b718ea2aea01c3e4cdc44a4c2a 491 Gene3D G3DSA:1.20.150.20 370 468 6.9E-24 T 11-11-2016 AUP74_RS02475 225a5311e231125d1399eb97d237418a 504 Gene3D G3DSA:3.40.50.1100 50 146 7.8E-38 T 11-11-2016 AUP74_RS02475 225a5311e231125d1399eb97d237418a 504 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 42 55 - T 11-11-2016 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 AUP74_RS02475 225a5311e231125d1399eb97d237418a 504 Gene3D G3DSA:3.40.1020.10 212 397 3.6E-52 T 11-11-2016 AUP74_RS02475 225a5311e231125d1399eb97d237418a 504 Gene3D G3DSA:3.40.1020.10 398 502 4.1E-44 T 11-11-2016 AUP74_RS02475 225a5311e231125d1399eb97d237418a 504 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 17 294 6.1E-82 T 11-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme AUP74_RS02475 225a5311e231125d1399eb97d237418a 504 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 319 408 7.3E-26 T 11-11-2016 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 AUP74_RS02475 225a5311e231125d1399eb97d237418a 504 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 418 502 9.2E-25 T 11-11-2016 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 AUP74_RS02475 225a5311e231125d1399eb97d237418a 504 TIGRFAM TIGR01124 ilvA_2Cterm: threonine ammonia-lyase, biosynthetic 5 502 4.1E-245 T 11-11-2016 IPR005787 Threonine dehydratase, biosynthetic GO:0004794|GO:0009097 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 AUP74_RS02475 225a5311e231125d1399eb97d237418a 504 SUPERFAMILY SSF55021 409 502 8.24E-28 T 11-11-2016 AUP74_RS02475 225a5311e231125d1399eb97d237418a 504 SUPERFAMILY SSF53686 4 355 8.91E-109 T 11-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme AUP74_RS11905 869e6340aeb5934170433e85bb055847 1160 Pfam PF00270 DEAD/DEAH box helicase 617 777 9.1E-18 T 11-11-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AUP74_RS11905 869e6340aeb5934170433e85bb055847 1160 Pfam PF02559 CarD-like/TRCF domain 492 587 1.2E-25 T 11-11-2016 IPR003711 CarD-like/TRCF domain AUP74_RS11905 869e6340aeb5934170433e85bb055847 1160 Pfam PF03461 TRCF domain 1022 1113 2.1E-27 T 11-11-2016 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 AUP74_RS11905 869e6340aeb5934170433e85bb055847 1160 Gene3D G3DSA:3.40.50.300 605 798 4.7E-57 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11905 869e6340aeb5934170433e85bb055847 1160 Pfam PF00271 Helicase conserved C-terminal domain 817 921 6.8E-18 T 11-11-2016 IPR001650 Helicase, C-terminal AUP74_RS11905 869e6340aeb5934170433e85bb055847 1160 SMART SM01058 491 588 2.7E-51 T 11-11-2016 IPR003711 CarD-like/TRCF domain AUP74_RS11905 869e6340aeb5934170433e85bb055847 1160 Gene3D G3DSA:3.40.50.300 810 975 1.1E-35 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11905 869e6340aeb5934170433e85bb055847 1160 SUPERFAMILY SSF52540 794 1002 1.61E-48 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11905 869e6340aeb5934170433e85bb055847 1160 Gene3D G3DSA:3.30.2060.10 143 220 6.0E-12 T 11-11-2016 AUP74_RS11905 869e6340aeb5934170433e85bb055847 1160 SMART SM00490 838 922 8.9E-18 T 11-11-2016 IPR001650 Helicase, C-terminal AUP74_RS11905 869e6340aeb5934170433e85bb055847 1160 SUPERFAMILY SSF52540 363 478 7.43E-27 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11905 869e6340aeb5934170433e85bb055847 1160 SUPERFAMILY SSF52540 9 354 2.3E-98 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11905 869e6340aeb5934170433e85bb055847 1160 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 158 1095 0.0 T 11-11-2016 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 AUP74_RS11905 869e6340aeb5934170433e85bb055847 1160 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 25 1120 28.974 T 11-11-2016 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 AUP74_RS11905 869e6340aeb5934170433e85bb055847 1160 SUPERFAMILY SSF143517 1013 1159 3.79E-41 T 11-11-2016 AUP74_RS11905 869e6340aeb5934170433e85bb055847 1160 SUPERFAMILY SSF52540 535 795 5.81E-62 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11905 869e6340aeb5934170433e85bb055847 1160 SMART SM00982 1021 1121 7.7E-50 T 11-11-2016 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 AUP74_RS11905 869e6340aeb5934170433e85bb055847 1160 SMART SM00487 612 802 6.4E-34 T 11-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain AUP74_RS11905 869e6340aeb5934170433e85bb055847 1160 SUPERFAMILY SSF141259 483 560 1.96E-23 T 11-11-2016 IPR003711 CarD-like/TRCF domain AUP74_RS16290 7c89c61f6882ce9f8d46577d620c066e 331 Gene3D G3DSA:1.10.260.40 3 53 1.7E-18 T 11-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AUP74_RS16290 7c89c61f6882ce9f8d46577d620c066e 331 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 48 9.2E-14 T 11-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AUP74_RS16290 7c89c61f6882ce9f8d46577d620c066e 331 Gene3D G3DSA:3.40.50.2300 169 307 1.2E-54 T 11-11-2016 AUP74_RS16290 7c89c61f6882ce9f8d46577d620c066e 331 Gene3D G3DSA:3.40.50.2300 54 168 4.0E-38 T 11-11-2016 AUP74_RS16290 7c89c61f6882ce9f8d46577d620c066e 331 Pfam PF13377 Periplasmic binding protein-like domain 165 326 1.0E-40 T 11-11-2016 AUP74_RS16290 7c89c61f6882ce9f8d46577d620c066e 331 SMART SM00354 1 71 2.6E-18 T 11-11-2016 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AUP74_RS16290 7c89c61f6882ce9f8d46577d620c066e 331 SUPERFAMILY SSF47413 2 57 7.88E-15 T 11-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AUP74_RS16290 7c89c61f6882ce9f8d46577d620c066e 331 SUPERFAMILY SSF53822 61 329 3.26E-79 T 11-11-2016 IPR028082 Periplasmic binding protein-like I AUP74_RS08985 05cdd6df025bb76c2aefa89fb0d000f6 963 Pfam PF02347 Glycine cleavage system P-protein 17 441 1.2E-178 T 11-11-2016 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 AUP74_RS08985 05cdd6df025bb76c2aefa89fb0d000f6 963 Pfam PF02347 Glycine cleavage system P-protein 476 738 4.4E-10 T 11-11-2016 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 AUP74_RS08985 05cdd6df025bb76c2aefa89fb0d000f6 963 SUPERFAMILY SSF53383 17 442 8.11E-107 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase AUP74_RS08985 05cdd6df025bb76c2aefa89fb0d000f6 963 Gene3D G3DSA:3.40.640.10 506 741 2.4E-38 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AUP74_RS08985 05cdd6df025bb76c2aefa89fb0d000f6 963 Gene3D G3DSA:3.40.640.10 88 307 1.8E-18 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AUP74_RS08985 05cdd6df025bb76c2aefa89fb0d000f6 963 SUPERFAMILY SSF53383 934 957 1.77E-97 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase AUP74_RS08985 05cdd6df025bb76c2aefa89fb0d000f6 963 SUPERFAMILY SSF53383 480 891 1.77E-97 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase AUP74_RS08985 05cdd6df025bb76c2aefa89fb0d000f6 963 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 18 955 0.0 T 11-11-2016 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 AUP74_RS08985 05cdd6df025bb76c2aefa89fb0d000f6 963 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 9 961 25.266 T 11-11-2016 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 AUP74_RS07730 1e31f60d67593ba0329000c43d6a0900 379 SUPERFAMILY SSF53474 270 283 3.91E-29 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS07730 1e31f60d67593ba0329000c43d6a0900 379 SUPERFAMILY SSF53474 114 241 3.91E-29 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS07730 1e31f60d67593ba0329000c43d6a0900 379 Pfam PF01764 Lipase (class 3) 119 239 4.7E-19 T 11-11-2016 IPR002921 Fungal lipase-like domain GO:0006629 Reactome: R-HSA-426048 AUP74_RS07730 1e31f60d67593ba0329000c43d6a0900 379 Gene3D G3DSA:3.40.50.1820 100 286 2.2E-34 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS03510 343ae3561301b09024b6c76ab024e8ef 499 SUPERFAMILY SSF50494 25 224 6.64E-37 T 11-11-2016 IPR009003 Peptidase S1, PA clan AUP74_RS03510 343ae3561301b09024b6c76ab024e8ef 499 Gene3D G3DSA:2.40.10.10 130 225 9.7E-18 T 11-11-2016 AUP74_RS03510 343ae3561301b09024b6c76ab024e8ef 499 Gene3D G3DSA:2.30.42.10 233 340 2.6E-13 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS03510 343ae3561301b09024b6c76ab024e8ef 499 PRINTS PR00834 HtrA/DegQ protease family signature 274 286 8.4E-13 T 11-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AUP74_RS03510 343ae3561301b09024b6c76ab024e8ef 499 PRINTS PR00834 HtrA/DegQ protease family signature 66 78 8.4E-13 T 11-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AUP74_RS03510 343ae3561301b09024b6c76ab024e8ef 499 PRINTS PR00834 HtrA/DegQ protease family signature 167 184 8.4E-13 T 11-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AUP74_RS03510 343ae3561301b09024b6c76ab024e8ef 499 PRINTS PR00834 HtrA/DegQ protease family signature 88 108 8.4E-13 T 11-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AUP74_RS03510 343ae3561301b09024b6c76ab024e8ef 499 Gene3D G3DSA:2.40.10.10 25 113 4.9E-14 T 11-11-2016 AUP74_RS03510 343ae3561301b09024b6c76ab024e8ef 499 Pfam PF13180 PDZ domain 253 335 9.1E-9 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS03510 343ae3561301b09024b6c76ab024e8ef 499 Pfam PF13365 Trypsin-like peptidase domain 58 195 9.1E-22 T 11-11-2016 AUP74_RS03510 343ae3561301b09024b6c76ab024e8ef 499 SUPERFAMILY SSF50156 258 347 2.1E-12 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS07800 4b86a77bce001ef18f08f7325d131f43 332 Gene3D G3DSA:3.40.250.10 104 226 1.5E-42 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS07800 4b86a77bce001ef18f08f7325d131f43 332 SUPERFAMILY SSF52821 93 244 1.1E-33 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS07800 4b86a77bce001ef18f08f7325d131f43 332 Pfam PF00581 Rhodanese-like domain 118 210 8.7E-11 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS07800 4b86a77bce001ef18f08f7325d131f43 332 SMART SM00450 113 214 6.6E-23 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS07800 4b86a77bce001ef18f08f7325d131f43 332 Hamap MF_00469 UPF0176 protein YceA [yceA]. 2 254 46.37 T 11-11-2016 IPR020936 Uncharacterised protein family UPF0176 AUP74_RS08495 5572b03a0938bd57d4cd5a95c00b7548 477 SUPERFAMILY SSF51905 1 71 3.4E-25 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS08495 5572b03a0938bd57d4cd5a95c00b7548 477 SUPERFAMILY SSF51905 298 398 3.4E-25 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS08495 5572b03a0938bd57d4cd5a95c00b7548 477 SUPERFAMILY SSF51905 115 213 3.4E-25 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS08495 5572b03a0938bd57d4cd5a95c00b7548 477 PIRSF PIRSF011396 1 476 9.9E-185 T 11-11-2016 IPR006905 Tryptophan halogenase AUP74_RS08495 5572b03a0938bd57d4cd5a95c00b7548 477 Pfam PF04820 Tryptophan halogenase 1 439 5.1E-176 T 11-11-2016 IPR006905 Tryptophan halogenase AUP74_RS08495 5572b03a0938bd57d4cd5a95c00b7548 477 Gene3D G3DSA:3.50.50.60 1 56 4.5E-37 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS08495 5572b03a0938bd57d4cd5a95c00b7548 477 Gene3D G3DSA:3.50.50.60 131 211 4.5E-37 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS08495 5572b03a0938bd57d4cd5a95c00b7548 477 Gene3D G3DSA:3.50.50.60 293 337 4.5E-37 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS13945 57572aa595f5340180fecf688b5732ab 396 Pfam PF07786 Protein of unknown function (DUF1624) 17 170 4.9E-12 T 11-11-2016 IPR012429 Protein of unknown function DUF1624 KEGG: 00531+2.3.1.78|Reactome: R-HSA-2024096|Reactome: R-HSA-2206291 AUP74_RS13930 0592bdb293fba5f897ad955945a475b2 429 PIRSF PIRSF000139 9 426 1.5E-106 T 11-11-2016 IPR012257 Glycolate oxidase, iron-sulphur subunit AUP74_RS13930 0592bdb293fba5f897ad955945a475b2 429 Gene3D G3DSA:1.10.1060.10 14 100 4.0E-20 T 11-11-2016 AUP74_RS13930 0592bdb293fba5f897ad955945a475b2 429 SUPERFAMILY SSF46548 10 100 1.15E-18 T 11-11-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 AUP74_RS13930 0592bdb293fba5f897ad955945a475b2 429 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 75 86 - T 11-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AUP74_RS13930 0592bdb293fba5f897ad955945a475b2 429 Pfam PF13183 4Fe-4S dicluster domain 22 89 4.7E-12 T 11-11-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AUP74_RS13930 0592bdb293fba5f897ad955945a475b2 429 Pfam PF02754 Cysteine-rich domain 183 267 1.1E-10 T 11-11-2016 IPR004017 Cysteine-rich domain AUP74_RS13930 0592bdb293fba5f897ad955945a475b2 429 Pfam PF02754 Cysteine-rich domain 318 401 3.7E-12 T 11-11-2016 IPR004017 Cysteine-rich domain AUP74_RS13930 0592bdb293fba5f897ad955945a475b2 429 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 25 36 - T 11-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AUP74_RS01590 d57dfa9185003ba61f7959a71877246b 231 Pfam PF03922 OmpW family 25 231 7.9E-53 T 11-11-2016 IPR005618 Outer membrane protein, OmpW GO:0019867 AUP74_RS01590 d57dfa9185003ba61f7959a71877246b 231 Gene3D G3DSA:2.40.160.20 25 231 1.3E-50 T 11-11-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AUP74_RS01590 d57dfa9185003ba61f7959a71877246b 231 ProSitePatterns PS00695 Enterobacterial virulence outer membrane protein signature 2. 223 231 - T 11-11-2016 IPR000758 Virulence-related outer membrane protein GO:0009279 AUP74_RS01590 d57dfa9185003ba61f7959a71877246b 231 SUPERFAMILY SSF56925 25 231 7.32E-20 T 11-11-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AUP74_RS00470 6ac559e0238f46fbe54628565062133b 458 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 73 352 7.2E-49 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS00470 6ac559e0238f46fbe54628565062133b 458 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 305 321 3.1E-19 T 11-11-2016 AUP74_RS00470 6ac559e0238f46fbe54628565062133b 458 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 220 238 3.1E-19 T 11-11-2016 AUP74_RS00470 6ac559e0238f46fbe54628565062133b 458 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 73 92 3.1E-19 T 11-11-2016 AUP74_RS00470 6ac559e0238f46fbe54628565062133b 458 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 330 352 3.1E-19 T 11-11-2016 AUP74_RS00470 6ac559e0238f46fbe54628565062133b 458 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 3.1E-19 T 11-11-2016 AUP74_RS00470 6ac559e0238f46fbe54628565062133b 458 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 72 94 3.6E-14 T 11-11-2016 AUP74_RS00470 6ac559e0238f46fbe54628565062133b 458 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 220 245 3.6E-14 T 11-11-2016 AUP74_RS00470 6ac559e0238f46fbe54628565062133b 458 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 306 320 3.6E-14 T 11-11-2016 AUP74_RS00470 6ac559e0238f46fbe54628565062133b 458 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 345 352 3.6E-14 T 11-11-2016 AUP74_RS00470 6ac559e0238f46fbe54628565062133b 458 ProSitePatterns PS00202 Rubredoxin signature. 27 37 - T 11-11-2016 IPR018527 Rubredoxin, iron-binding site GO:0046872 AUP74_RS00470 6ac559e0238f46fbe54628565062133b 458 SUPERFAMILY SSF57802 2 46 7.57E-18 T 11-11-2016 AUP74_RS00470 6ac559e0238f46fbe54628565062133b 458 SUPERFAMILY SSF51905 72 378 1.2E-36 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS00470 6ac559e0238f46fbe54628565062133b 458 Pfam PF00301 Rubredoxin 2 43 2.8E-20 T 11-11-2016 IPR024935 Rubredoxin domain GO:0005506 AUP74_RS00470 6ac559e0238f46fbe54628565062133b 458 Gene3D G3DSA:3.50.50.60 178 374 8.9E-38 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS00470 6ac559e0238f46fbe54628565062133b 458 Gene3D G3DSA:3.50.50.60 72 177 8.2E-19 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS00470 6ac559e0238f46fbe54628565062133b 458 Gene3D G3DSA:2.20.28.10 2 46 2.1E-21 T 11-11-2016 IPR004039 Rubredoxin-type fold AUP74_RS00035 f6b6de20286e89d97df63eb8eb6f5695 286 Pfam PF03668 P-loop ATPase protein family 1 284 6.8E-93 T 11-11-2016 IPR005337 RapZ-like family GO:0005524 AUP74_RS00035 f6b6de20286e89d97df63eb8eb6f5695 286 PIRSF PIRSF005052 1 286 4.2E-111 T 11-11-2016 IPR005337 RapZ-like family GO:0005524 AUP74_RS00035 f6b6de20286e89d97df63eb8eb6f5695 286 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 1 286 40.452 T 11-11-2016 IPR005337 RapZ-like family GO:0005524 AUP74_RS00035 f6b6de20286e89d97df63eb8eb6f5695 286 SUPERFAMILY SSF52540 1 156 3.26E-13 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS00035 f6b6de20286e89d97df63eb8eb6f5695 286 Gene3D G3DSA:3.40.50.300 1 154 1.5E-15 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS06170 0b3b6e98d10fc5905c2e269beb0582b1 542 Pfam PF08241 Methyltransferase domain 299 393 1.1E-21 T 11-11-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 AUP74_RS06170 0b3b6e98d10fc5905c2e269beb0582b1 542 Gene3D G3DSA:3.40.50.1820 5 242 7.0E-35 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS06170 0b3b6e98d10fc5905c2e269beb0582b1 542 TIGRFAM TIGR02072 BioC: malonyl-acyl carrier protein O-methyltransferase BioC 263 505 6.2E-67 T 11-11-2016 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00670+2.1.1.19|KEGG: 00780+2.1.1.197|MetaCyc: PWY-2201|MetaCyc: PWY-6519 AUP74_RS06170 0b3b6e98d10fc5905c2e269beb0582b1 542 Hamap MF_00835 Malonyl-[acyl-carrier protein] O-methyltransferase [bioC]. 255 509 30.762 T 11-11-2016 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00670+2.1.1.19|KEGG: 00780+2.1.1.197|MetaCyc: PWY-2201|MetaCyc: PWY-6519 AUP74_RS06170 0b3b6e98d10fc5905c2e269beb0582b1 542 SUPERFAMILY SSF53335 260 461 1.99E-38 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS06170 0b3b6e98d10fc5905c2e269beb0582b1 542 Pfam PF12697 Alpha/beta hydrolase family 6 232 8.4E-21 T 11-11-2016 IPR000073 Alpha/beta hydrolase fold-1 AUP74_RS06170 0b3b6e98d10fc5905c2e269beb0582b1 542 SUPERFAMILY SSF53474 5 242 1.37E-34 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS06170 0b3b6e98d10fc5905c2e269beb0582b1 542 Gene3D G3DSA:3.40.50.150 260 489 2.4E-36 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS02870 c75f3a5e15fec50be9aea808e880e207 302 SUPERFAMILY SSF103481 187 285 1.06E-9 T 11-11-2016 AUP74_RS02870 c75f3a5e15fec50be9aea808e880e207 302 SUPERFAMILY SSF103481 50 142 4.84E-11 T 11-11-2016 AUP74_RS02870 c75f3a5e15fec50be9aea808e880e207 302 Pfam PF00892 EamA-like transporter family 10 141 7.8E-14 T 11-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 AUP74_RS02870 c75f3a5e15fec50be9aea808e880e207 302 Pfam PF00892 EamA-like transporter family 154 284 5.9E-10 T 11-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 AUP74_RS02870 c75f3a5e15fec50be9aea808e880e207 302 TIGRFAM TIGR00688 rarD: protein RarD 9 258 4.1E-79 T 11-11-2016 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 AUP74_RS13500 a968910784c827ec334f6905ff5f6bf3 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 6.2E-29 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS13500 a968910784c827ec334f6905ff5f6bf3 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 6.2E-29 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS13500 a968910784c827ec334f6905ff5f6bf3 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 6.2E-29 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS13500 a968910784c827ec334f6905ff5f6bf3 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 6.2E-29 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS13500 a968910784c827ec334f6905ff5f6bf3 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 6.2E-29 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS13500 a968910784c827ec334f6905ff5f6bf3 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 6.2E-29 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS13500 a968910784c827ec334f6905ff5f6bf3 297 Gene3D G3DSA:3.40.50.720 10 259 3.1E-71 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS13500 a968910784c827ec334f6905ff5f6bf3 297 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 24 255 3.0E-50 T 11-11-2016 AUP74_RS13500 a968910784c827ec334f6905ff5f6bf3 297 SUPERFAMILY SSF51735 14 257 2.0E-68 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS01485 f0c601535921efcc1961c3bda821c14e 92 Pfam PF02609 Exonuclease VII small subunit 10 60 9.0E-22 T 11-11-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 AUP74_RS01485 f0c601535921efcc1961c3bda821c14e 92 Gene3D G3DSA:1.10.287.1040 4 75 9.5E-29 T 11-11-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 AUP74_RS01485 f0c601535921efcc1961c3bda821c14e 92 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 9 65 2.0E-24 T 11-11-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 AUP74_RS01485 f0c601535921efcc1961c3bda821c14e 92 PIRSF PIRSF006488 1 82 1.6E-24 T 11-11-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 AUP74_RS01485 f0c601535921efcc1961c3bda821c14e 92 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 9 69 16.746 T 11-11-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 AUP74_RS01485 f0c601535921efcc1961c3bda821c14e 92 SUPERFAMILY SSF116842 3 69 4.32E-22 T 11-11-2016 AUP74_RS01485 f0c601535921efcc1961c3bda821c14e 92 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 27 49 8.0E-4 T 11-11-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 AUP74_RS02985 ec1bd9b642795403f8c26ebf9d9d7995 327 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 73 88 1.2E-12 T 11-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AUP74_RS02985 ec1bd9b642795403f8c26ebf9d9d7995 327 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 73 1.2E-12 T 11-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AUP74_RS02985 ec1bd9b642795403f8c26ebf9d9d7995 327 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 26 41 1.2E-12 T 11-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AUP74_RS02985 ec1bd9b642795403f8c26ebf9d9d7995 327 SUPERFAMILY SSF46785 18 177 2.73E-25 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS02985 ec1bd9b642795403f8c26ebf9d9d7995 327 SUPERFAMILY SSF53335 146 300 4.14E-35 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS02985 ec1bd9b642795403f8c26ebf9d9d7995 327 Pfam PF13489 Methyltransferase domain 152 284 9.5E-19 T 11-11-2016 AUP74_RS02985 ec1bd9b642795403f8c26ebf9d9d7995 327 SMART SM00418 24 98 4.8E-20 T 11-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AUP74_RS02985 ec1bd9b642795403f8c26ebf9d9d7995 327 Gene3D G3DSA:3.40.50.150 119 297 2.6E-32 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS02985 ec1bd9b642795403f8c26ebf9d9d7995 327 Gene3D G3DSA:1.10.10.10 7 102 3.9E-27 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS02985 ec1bd9b642795403f8c26ebf9d9d7995 327 Pfam PF01022 Bacterial regulatory protein, arsR family 31 77 1.3E-15 T 11-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AUP74_RS10645 d5ceb713aed0bafa317e305d37182aa9 188 Pfam PF00881 Nitroreductase family 9 164 1.1E-21 T 11-11-2016 IPR029479 Nitroreductase Reactome: R-HSA-209968 AUP74_RS10645 d5ceb713aed0bafa317e305d37182aa9 188 PIRSF PIRSF000232 1 188 2.7E-61 T 11-11-2016 IPR026021 Putative NAD(P)H nitroreductase YdjA-like AUP74_RS10645 d5ceb713aed0bafa317e305d37182aa9 188 SUPERFAMILY SSF55469 1 184 4.97E-39 T 11-11-2016 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AUP74_RS10645 d5ceb713aed0bafa317e305d37182aa9 188 Gene3D G3DSA:3.40.109.10 1 185 2.0E-37 T 11-11-2016 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AUP74_RS03675 faceaf17e131d0fd8a3f26dbc25a4ca6 197 Gene3D G3DSA:1.10.340.30 4 184 1.1E-83 T 11-11-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AUP74_RS03675 faceaf17e131d0fd8a3f26dbc25a4ca6 197 TIGRFAM TIGR00624 tag: DNA-3-methyladenine glycosylase I 5 182 6.2E-77 T 11-11-2016 IPR004597 DNA-3-methyladenine glycosylase I GO:0006284|GO:0008725 AUP74_RS03675 faceaf17e131d0fd8a3f26dbc25a4ca6 197 SUPERFAMILY SSF48150 4 188 1.41E-79 T 11-11-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AUP74_RS03675 faceaf17e131d0fd8a3f26dbc25a4ca6 197 Pfam PF03352 Methyladenine glycosylase 8 183 1.3E-79 T 11-11-2016 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 AUP74_RS11665 d7af892ba43d69958ac50446a3e8af92 208 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 31 205 37.875 T 11-11-2016 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 AUP74_RS11665 d7af892ba43d69958ac50446a3e8af92 208 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 15 200 5.7E-79 T 11-11-2016 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 AUP74_RS11665 d7af892ba43d69958ac50446a3e8af92 208 Pfam PF01583 Adenylylsulphate kinase 32 188 2.3E-70 T 11-11-2016 AUP74_RS11665 d7af892ba43d69958ac50446a3e8af92 208 SUPERFAMILY SSF52540 31 204 1.62E-37 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11665 d7af892ba43d69958ac50446a3e8af92 208 Gene3D G3DSA:3.40.50.300 10 207 4.6E-88 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS00550 38538adb4cbb9da9009a7877ebed768b 393 SUPERFAMILY SSF81606 191 388 2.35E-6 T 11-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 AUP74_RS00550 38538adb4cbb9da9009a7877ebed768b 393 Pfam PF00072 Response regulator receiver domain 8 114 1.7E-21 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS00550 38538adb4cbb9da9009a7877ebed768b 393 SMART SM00331 174 392 1.9E-7 T 11-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 AUP74_RS00550 38538adb4cbb9da9009a7877ebed768b 393 Gene3D G3DSA:3.40.50.2300 6 145 5.5E-29 T 11-11-2016 AUP74_RS00550 38538adb4cbb9da9009a7877ebed768b 393 SUPERFAMILY SSF52172 5 143 3.98E-29 T 11-11-2016 IPR011006 CheY-like superfamily AUP74_RS00550 38538adb4cbb9da9009a7877ebed768b 393 SMART SM00448 5 116 9.0E-25 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS00550 38538adb4cbb9da9009a7877ebed768b 393 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 204 391 3.5E-26 T 11-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 AUP74_RS06885 8df7bb473b8e65a59187a8bd024ef278 179 SUPERFAMILY SSF55282 4 178 2.33E-77 T 11-11-2016 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06885 8df7bb473b8e65a59187a8bd024ef278 179 Gene3D G3DSA:3.30.1440.10 2 178 5.4E-77 T 11-11-2016 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06885 8df7bb473b8e65a59187a8bd024ef278 179 Pfam PF00281 Ribosomal protein L5 24 80 7.9E-29 T 11-11-2016 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06885 8df7bb473b8e65a59187a8bd024ef278 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 11-11-2016 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06885 8df7bb473b8e65a59187a8bd024ef278 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 43.215 T 11-11-2016 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS06885 8df7bb473b8e65a59187a8bd024ef278 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 1.4E-41 T 11-11-2016 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06885 8df7bb473b8e65a59187a8bd024ef278 179 PIRSF PIRSF002161 1 179 8.1E-67 T 11-11-2016 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS11825 2940284dfd3a40e3b37b19c8d5a590a0 658 SUPERFAMILY SSF53955 498 651 2.48E-46 T 11-11-2016 IPR023346 Lysozyme-like domain AUP74_RS11825 2940284dfd3a40e3b37b19c8d5a590a0 658 Gene3D G3DSA:1.10.530.10 497 653 2.2E-49 T 11-11-2016 AUP74_RS11825 2940284dfd3a40e3b37b19c8d5a590a0 658 SUPERFAMILY SSF48435 37 487 5.36E-112 T 11-11-2016 IPR016026 Lytic transglycosylase, superhelical U-shaped and linker domain GO:0004553|GO:0042597 AUP74_RS11825 2940284dfd3a40e3b37b19c8d5a590a0 658 Gene3D G3DSA:1.25.20.10 37 397 7.3E-93 T 11-11-2016 IPR008939 Lytic transglycosylase, superhelical U-shaped GO:0004553|GO:0042597 AUP74_RS11825 2940284dfd3a40e3b37b19c8d5a590a0 658 Pfam PF01464 Transglycosylase SLT domain 500 609 1.1E-28 T 11-11-2016 IPR008258 Transglycosylase SLT domain 1 AUP74_RS11825 2940284dfd3a40e3b37b19c8d5a590a0 658 Gene3D G3DSA:1.10.1240.20 418 482 1.6E-13 T 11-11-2016 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 AUP74_RS11825 2940284dfd3a40e3b37b19c8d5a590a0 658 Pfam PF14718 Soluble lytic murein transglycosylase L domain 418 482 2.1E-15 T 11-11-2016 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 AUP74_RS05485 bb76304e1fc4e67fc33d60a5d2dc4e4b 382 SUPERFAMILY SSF52540 4 336 3.66E-69 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05485 bb76304e1fc4e67fc33d60a5d2dc4e4b 382 Pfam PF00437 Type II/IV secretion system protein 118 249 6.8E-34 T 11-11-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 AUP74_RS05485 bb76304e1fc4e67fc33d60a5d2dc4e4b 382 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 3 344 1.7E-135 T 11-11-2016 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 AUP74_RS05485 bb76304e1fc4e67fc33d60a5d2dc4e4b 382 Gene3D G3DSA:3.40.50.300 102 344 1.2E-62 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05485 bb76304e1fc4e67fc33d60a5d2dc4e4b 382 SMART SM00382 122 247 0.006 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS02705 a5c65aedd4a75888c0685eaa327d5f2b 698 Pfam PF01464 Transglycosylase SLT domain 533 635 7.6E-23 T 11-11-2016 IPR008258 Transglycosylase SLT domain 1 AUP74_RS02705 a5c65aedd4a75888c0685eaa327d5f2b 698 Gene3D G3DSA:3.40.190.10 58 146 4.6E-12 T 11-11-2016 AUP74_RS02705 a5c65aedd4a75888c0685eaa327d5f2b 698 SUPERFAMILY SSF53955 520 686 4.25E-38 T 11-11-2016 IPR023346 Lysozyme-like domain AUP74_RS02705 a5c65aedd4a75888c0685eaa327d5f2b 698 SUPERFAMILY SSF53850 25 248 4.75E-24 T 11-11-2016 AUP74_RS02705 a5c65aedd4a75888c0685eaa327d5f2b 698 Gene3D G3DSA:3.40.190.10 460 500 4.3E-20 T 11-11-2016 AUP74_RS02705 a5c65aedd4a75888c0685eaa327d5f2b 698 Gene3D G3DSA:3.40.190.10 269 358 4.3E-20 T 11-11-2016 AUP74_RS02705 a5c65aedd4a75888c0685eaa327d5f2b 698 SMART SM00062 272 501 1.2E-25 T 11-11-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AUP74_RS02705 a5c65aedd4a75888c0685eaa327d5f2b 698 SMART SM00062 32 268 2.1E-4 T 11-11-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AUP74_RS02705 a5c65aedd4a75888c0685eaa327d5f2b 698 SUPERFAMILY SSF53850 273 500 6.64E-33 T 11-11-2016 AUP74_RS02705 a5c65aedd4a75888c0685eaa327d5f2b 698 Gene3D G3DSA:1.10.530.10 517 687 6.2E-42 T 11-11-2016 AUP74_RS02705 a5c65aedd4a75888c0685eaa327d5f2b 698 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 58 248 6.2E-20 T 11-11-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AUP74_RS02705 a5c65aedd4a75888c0685eaa327d5f2b 698 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 274 499 1.3E-26 T 11-11-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AUP74_RS04390 8403eaa719a2e487b378e91c5f312d69 466 SUPERFAMILY SSF47917 350 464 9.94E-55 T 11-11-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AUP74_RS04390 8403eaa719a2e487b378e91c5f312d69 466 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 338 347 - T 11-11-2016 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AUP74_RS04390 8403eaa719a2e487b378e91c5f312d69 466 Gene3D G3DSA:3.40.50.300 74 348 3.0E-108 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04390 8403eaa719a2e487b378e91c5f312d69 466 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 128 347 2.8E-61 T 11-11-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AUP74_RS04390 8403eaa719a2e487b378e91c5f312d69 466 SUPERFAMILY SSF50615 1 73 1.1E-24 T 11-11-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AUP74_RS04390 8403eaa719a2e487b378e91c5f312d69 466 Gene3D G3DSA:2.40.10.170 2 73 4.2E-28 T 11-11-2016 AUP74_RS04390 8403eaa719a2e487b378e91c5f312d69 466 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 464 3.6E-252 T 11-11-2016 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 AUP74_RS04390 8403eaa719a2e487b378e91c5f312d69 466 SMART SM00382 140 332 4.9E-4 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS04390 8403eaa719a2e487b378e91c5f312d69 466 SUPERFAMILY SSF52540 75 353 1.64E-87 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04390 8403eaa719a2e487b378e91c5f312d69 466 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 465 56.616 T 11-11-2016 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 AUP74_RS04390 8403eaa719a2e487b378e91c5f312d69 466 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 71 4.8E-21 T 11-11-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AUP74_RS04390 8403eaa719a2e487b378e91c5f312d69 466 Gene3D G3DSA:1.10.1140.10 350 465 1.5E-56 T 11-11-2016 IPR024034 ATPase, F1 complex beta subunit/V1 complex, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 AUP74_RS12380 dc0c1209e2ba2c6e9f87bc78f901be91 736 SUPERFAMILY SSF55874 295 436 3.83E-19 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS12380 dc0c1209e2ba2c6e9f87bc78f901be91 736 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 336 445 5.5E-11 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS12380 dc0c1209e2ba2c6e9f87bc78f901be91 736 SUPERFAMILY SSF52172 611 734 9.39E-24 T 11-11-2016 IPR011006 CheY-like superfamily AUP74_RS12380 dc0c1209e2ba2c6e9f87bc78f901be91 736 Pfam PF00072 Response regulator receiver domain 615 729 6.4E-16 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS12380 dc0c1209e2ba2c6e9f87bc78f901be91 736 SUPERFAMILY SSF47384 211 287 1.57E-6 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS12380 dc0c1209e2ba2c6e9f87bc78f901be91 736 Gene3D G3DSA:3.40.50.2300 609 734 2.1E-26 T 11-11-2016 AUP74_RS12380 dc0c1209e2ba2c6e9f87bc78f901be91 736 SMART SM00387 336 447 5.0E-7 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS12380 dc0c1209e2ba2c6e9f87bc78f901be91 736 Gene3D G3DSA:3.30.565.10 298 443 2.6E-20 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS12380 dc0c1209e2ba2c6e9f87bc78f901be91 736 SMART SM00448 612 729 1.7E-16 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS16205 7461fd9d0e3a7c1029b4ebdd91d31cdf 159 SUPERFAMILY SSF47240 1 154 1.29E-58 T 11-11-2016 IPR009078 Ferritin-like superfamily AUP74_RS16205 7461fd9d0e3a7c1029b4ebdd91d31cdf 159 TIGRFAM TIGR00754 bfr: bacterioferritin 1 156 3.4E-79 T 11-11-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AUP74_RS16205 7461fd9d0e3a7c1029b4ebdd91d31cdf 159 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 11-11-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AUP74_RS16205 7461fd9d0e3a7c1029b4ebdd91d31cdf 159 PIRSF PIRSF002560 1 157 1.7E-74 T 11-11-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AUP74_RS16205 7461fd9d0e3a7c1029b4ebdd91d31cdf 159 Gene3D G3DSA:1.20.1260.10 1 156 9.7E-71 T 11-11-2016 IPR012347 Ferritin-related AUP74_RS16205 7461fd9d0e3a7c1029b4ebdd91d31cdf 159 PRINTS PR00601 Bacterioferritin signature 128 149 1.7E-72 T 11-11-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AUP74_RS16205 7461fd9d0e3a7c1029b4ebdd91d31cdf 159 PRINTS PR00601 Bacterioferritin signature 3 22 1.7E-72 T 11-11-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AUP74_RS16205 7461fd9d0e3a7c1029b4ebdd91d31cdf 159 PRINTS PR00601 Bacterioferritin signature 23 43 1.7E-72 T 11-11-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AUP74_RS16205 7461fd9d0e3a7c1029b4ebdd91d31cdf 159 PRINTS PR00601 Bacterioferritin signature 44 64 1.7E-72 T 11-11-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AUP74_RS16205 7461fd9d0e3a7c1029b4ebdd91d31cdf 159 PRINTS PR00601 Bacterioferritin signature 65 85 1.7E-72 T 11-11-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AUP74_RS16205 7461fd9d0e3a7c1029b4ebdd91d31cdf 159 PRINTS PR00601 Bacterioferritin signature 107 127 1.7E-72 T 11-11-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AUP74_RS16205 7461fd9d0e3a7c1029b4ebdd91d31cdf 159 PRINTS PR00601 Bacterioferritin signature 86 106 1.7E-72 T 11-11-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AUP74_RS16205 7461fd9d0e3a7c1029b4ebdd91d31cdf 159 Pfam PF00210 Ferritin-like domain 8 143 1.1E-42 T 11-11-2016 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 AUP74_RS03730 aed07e3e9ed9cdc8cbf21cd1371632c5 89 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 5 49 5.7E-22 T 11-11-2016 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 AUP74_RS03730 aed07e3e9ed9cdc8cbf21cd1371632c5 89 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 3 88 24.661 T 11-11-2016 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 AUP74_RS03730 aed07e3e9ed9cdc8cbf21cd1371632c5 89 Pfam PF02416 mttA/Hcf106 family 6 55 3.8E-14 T 11-11-2016 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 AUP74_RS12885 bcb329ad36200e5e952694f0ac985954 326 SUPERFAMILY SSF52317 75 257 1.43E-12 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS12885 bcb329ad36200e5e952694f0ac985954 326 Pfam PF03575 Peptidase family S51 54 148 9.1E-8 T 11-11-2016 IPR005320 Peptidase S51 GO:0006508|GO:0008236 AUP74_RS12885 bcb329ad36200e5e952694f0ac985954 326 Gene3D G3DSA:3.40.50.880 50 269 4.0E-12 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS08185 b742a892cf5444bea61953007fd73f22 153 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 6 152 26.625 T 11-11-2016 IPR003728 Ribosome maturation factor RimP GO:0042274 AUP74_RS08185 b742a892cf5444bea61953007fd73f22 153 SUPERFAMILY SSF75420 2 83 3.01E-27 T 11-11-2016 IPR028989 Ribosome maturation factor RimP, N-terminal AUP74_RS08185 b742a892cf5444bea61953007fd73f22 153 SUPERFAMILY SSF74942 84 152 1.7E-18 T 11-11-2016 IPR028998 Ribosome maturation factor RimP, C-terminal AUP74_RS08185 b742a892cf5444bea61953007fd73f22 153 Pfam PF02576 Putative ribosome maturation factor RimP 12 148 8.9E-49 T 11-11-2016 IPR003728 Ribosome maturation factor RimP GO:0042274 AUP74_RS08185 b742a892cf5444bea61953007fd73f22 153 Gene3D G3DSA:3.30.300.70 2 80 9.0E-33 T 11-11-2016 IPR028989 Ribosome maturation factor RimP, N-terminal AUP74_RS08185 b742a892cf5444bea61953007fd73f22 153 Gene3D G3DSA:2.30.30.180 89 148 1.5E-14 T 11-11-2016 IPR028998 Ribosome maturation factor RimP, C-terminal AUP74_RS02955 5a88beb0f250be6df4a649ddc8e4cbfc 472 SUPERFAMILY SSF56601 3 315 1.66E-58 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS02955 5a88beb0f250be6df4a649ddc8e4cbfc 472 Gene3D G3DSA:3.40.710.10 2 315 1.8E-59 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS02955 5a88beb0f250be6df4a649ddc8e4cbfc 472 Pfam PF00144 Beta-lactamase 3 306 1.6E-43 T 11-11-2016 IPR001466 Beta-lactamase-related AUP74_RS04030 43fad0bdc1c8f28c4d6487b34cdfadbc 255 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 251 3.5E-50 T 11-11-2016 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 AUP74_RS04030 43fad0bdc1c8f28c4d6487b34cdfadbc 255 Gene3D G3DSA:3.60.10.10 1 252 3.4E-56 T 11-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase AUP74_RS04030 43fad0bdc1c8f28c4d6487b34cdfadbc 255 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 17 242 2.6E-8 T 11-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase AUP74_RS04030 43fad0bdc1c8f28c4d6487b34cdfadbc 255 SUPERFAMILY SSF56219 1 253 3.93E-41 T 11-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase AUP74_RS10725 2ac78b24b1cd949ee5d58b0ea4cde8bf 309 SUPERFAMILY SSF52540 2 164 3.1E-31 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS10725 2ac78b24b1cd949ee5d58b0ea4cde8bf 309 Gene3D G3DSA:3.30.1220.10 201 305 8.7E-21 T 11-11-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal AUP74_RS10725 2ac78b24b1cd949ee5d58b0ea4cde8bf 309 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 212 303 2.3E-19 T 11-11-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal AUP74_RS10725 2ac78b24b1cd949ee5d58b0ea4cde8bf 309 SUPERFAMILY SSF90002 212 304 1.05E-17 T 11-11-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal AUP74_RS10725 2ac78b24b1cd949ee5d58b0ea4cde8bf 309 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 2 170 1.8E-46 T 11-11-2016 IPR003495 CobW/HypB/UreG, nucleotide-binding domain AUP74_RS10725 2ac78b24b1cd949ee5d58b0ea4cde8bf 309 Gene3D G3DSA:3.40.50.300 1 193 3.6E-56 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS10725 2ac78b24b1cd949ee5d58b0ea4cde8bf 309 SMART SM00833 212 304 4.1E-18 T 11-11-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal AUP74_RS16580 fd10da6f59eae4ce502f276a4c121fa2 124 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2 118 8.3E-30 T 11-11-2016 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AUP74_RS16580 fd10da6f59eae4ce502f276a4c121fa2 124 ProSitePatterns PS01001 Succinate dehydrogenase cytochrome b subunit signature 2. 80 93 - T 11-11-2016 IPR018495 Succinate dehydrogenase, cytochrome b subunit, conserved site GO:0000104|GO:0006099|GO:0009055|GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AUP74_RS16580 fd10da6f59eae4ce502f276a4c121fa2 124 Gene3D G3DSA:1.20.1300.10 2 124 2.2E-38 T 11-11-2016 AUP74_RS16580 fd10da6f59eae4ce502f276a4c121fa2 124 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 3 122 1.5E-39 T 11-11-2016 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AUP74_RS16580 fd10da6f59eae4ce502f276a4c121fa2 124 SUPERFAMILY SSF81343 2 124 1.02E-31 T 11-11-2016 AUP74_RS16580 fd10da6f59eae4ce502f276a4c121fa2 124 PIRSF PIRSF000178 1 124 1.4E-28 T 11-11-2016 AUP74_RS15305 37243806ea1384dd55dd1eb4290b6333 233 SUPERFAMILY SSF53067 3 105 2.24E-30 T 11-11-2016 AUP74_RS15305 37243806ea1384dd55dd1eb4290b6333 233 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 219 6.5E-59 T 11-11-2016 IPR022496 tRNA threonylcarbamoyl adenosine modification protein YeaZ GO:0002949 AUP74_RS15305 37243806ea1384dd55dd1eb4290b6333 233 Pfam PF00814 Glycoprotease family 29 131 3.0E-30 T 11-11-2016 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 AUP74_RS15305 37243806ea1384dd55dd1eb4290b6333 233 Gene3D G3DSA:3.30.420.40 2 131 1.3E-43 T 11-11-2016 AUP74_RS15305 37243806ea1384dd55dd1eb4290b6333 233 SUPERFAMILY SSF53067 113 217 2.2E-14 T 11-11-2016 AUP74_RS08770 6e84cc85f3e31d594c80bb76041c2095 469 Pfam PF13727 CoA-binding domain 61 241 1.0E-34 T 11-11-2016 AUP74_RS08770 6e84cc85f3e31d594c80bb76041c2095 469 Pfam PF02397 Bacterial sugar transferase 279 461 1.5E-57 T 11-11-2016 IPR003362 Bacterial sugar transferase AUP74_RS08770 6e84cc85f3e31d594c80bb76041c2095 469 SUPERFAMILY SSF51735 141 275 1.5E-7 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS08770 6e84cc85f3e31d594c80bb76041c2095 469 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 36 469 5.9E-149 T 11-11-2016 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase AUP74_RS08770 6e84cc85f3e31d594c80bb76041c2095 469 TIGRFAM TIGR03023 WcaJ_sugtrans: undecaprenyl-phosphate glucose phosphotransferase 28 469 1.7E-167 T 11-11-2016 IPR017473 Undecaprenyl-phosphate glucose phosphotransferase, WcaJ MetaCyc: PWY-6655|MetaCyc: PWY-6658 AUP74_RS00050 53c72f07522ced46f7368f0202136e10 170 Gene3D G3DSA:1.10.60.30 103 169 3.6E-21 T 11-11-2016 IPR023153 PSPTO4464-like domain AUP74_RS00050 53c72f07522ced46f7368f0202136e10 170 Pfam PF04751 Protein of unknown function (DUF615) 13 163 1.8E-50 T 11-11-2016 IPR006839 Ribosome-associated, YjgA AUP74_RS00050 53c72f07522ced46f7368f0202136e10 170 SUPERFAMILY SSF158710 22 166 1.83E-48 T 11-11-2016 AUP74_RS00050 53c72f07522ced46f7368f0202136e10 170 PIRSF PIRSF016183 1 170 7.1E-56 T 11-11-2016 IPR006839 Ribosome-associated, YjgA AUP74_RS00050 53c72f07522ced46f7368f0202136e10 170 Gene3D G3DSA:1.10.60.30 22 95 1.3E-30 T 11-11-2016 IPR023153 PSPTO4464-like domain AUP74_RS03300 fa1633e8f14fee9dd23727c578e6947d 412 Gene3D G3DSA:1.10.443.10 209 394 3.8E-19 T 11-11-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 AUP74_RS03300 fa1633e8f14fee9dd23727c578e6947d 412 Gene3D G3DSA:1.10.150.130 99 193 7.9E-21 T 11-11-2016 IPR023109 Integrase/recombinase, N-terminal AUP74_RS03300 fa1633e8f14fee9dd23727c578e6947d 412 SUPERFAMILY SSF56349 100 398 3.53E-53 T 11-11-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AUP74_RS03300 fa1633e8f14fee9dd23727c578e6947d 412 Pfam PF00589 Phage integrase family 210 358 2.5E-10 T 11-11-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AUP74_RS03300 fa1633e8f14fee9dd23727c578e6947d 412 Pfam PF13356 Domain of unknown function (DUF4102) 4 87 5.1E-17 T 11-11-2016 IPR025166 Domain of unknown function DUF4102 AUP74_RS08500 53a2b91e22cec59ca46b6ec68cba1fab 421 Gene3D G3DSA:1.20.1250.20 24 215 1.7E-15 T 11-11-2016 AUP74_RS08500 53a2b91e22cec59ca46b6ec68cba1fab 421 Pfam PF07690 Major Facilitator Superfamily 30 361 8.8E-15 T 11-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AUP74_RS08500 53a2b91e22cec59ca46b6ec68cba1fab 421 Gene3D G3DSA:1.20.1250.20 237 408 1.5E-9 T 11-11-2016 AUP74_RS08500 53a2b91e22cec59ca46b6ec68cba1fab 421 SUPERFAMILY SSF103473 17 411 1.11E-36 T 11-11-2016 IPR020846 Major facilitator superfamily domain AUP74_RS08500 53a2b91e22cec59ca46b6ec68cba1fab 421 TIGRFAM TIGR01272 gluP: glucose/galactose transporter WARNING 104 411 4.5E-121 T 11-11-2016 IPR005964 Bacterial glucose/galactose transporter GO:0005354|GO:0005355|GO:0009276|GO:0015757|GO:0015758|GO:0016021 AUP74_RS08215 b099e32e46af217492d5a121a8d5e087 706 Gene3D G3DSA:1.10.10.400 226 312 3.8E-23 T 11-11-2016 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 AUP74_RS08215 b099e32e46af217492d5a121a8d5e087 706 Gene3D G3DSA:2.40.50.140 619 691 9.0E-26 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS08215 b099e32e46af217492d5a121a8d5e087 706 Pfam PF03725 3' exoribonuclease family, domain 2 146 210 9.5E-10 T 11-11-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AUP74_RS08215 b099e32e46af217492d5a121a8d5e087 706 Pfam PF03725 3' exoribonuclease family, domain 2 457 525 5.3E-7 T 11-11-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AUP74_RS08215 b099e32e46af217492d5a121a8d5e087 706 PIRSF PIRSF005499 1 706 1.8E-297 T 11-11-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 AUP74_RS08215 b099e32e46af217492d5a121a8d5e087 706 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 242 318 6.9E-18 T 11-11-2016 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 AUP74_RS08215 b099e32e46af217492d5a121a8d5e087 706 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 9 689 0.0 T 11-11-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 AUP74_RS08215 b099e32e46af217492d5a121a8d5e087 706 Pfam PF01138 3' exoribonuclease family, domain 1 14 143 7.8E-24 T 11-11-2016 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AUP74_RS08215 b099e32e46af217492d5a121a8d5e087 706 Pfam PF01138 3' exoribonuclease family, domain 1 322 454 2.7E-20 T 11-11-2016 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AUP74_RS08215 b099e32e46af217492d5a121a8d5e087 706 SUPERFAMILY SSF50249 618 701 1.14E-21 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS08215 b099e32e46af217492d5a121a8d5e087 706 Gene3D G3DSA:3.30.1370.10 550 618 3.3E-26 T 11-11-2016 IPR004088 K Homology domain, type 1 GO:0003723 AUP74_RS08215 b099e32e46af217492d5a121a8d5e087 706 Pfam PF00575 S1 RNA binding domain 617 688 2.0E-17 T 11-11-2016 IPR003029 S1 domain GO:0003676 AUP74_RS08215 b099e32e46af217492d5a121a8d5e087 706 SMART SM00316 618 688 8.4E-24 T 11-11-2016 IPR022967 RNA-binding domain, S1 AUP74_RS08215 b099e32e46af217492d5a121a8d5e087 706 SMART SM00322 550 615 4.1E-15 T 11-11-2016 IPR004087 K Homology domain GO:0003676 AUP74_RS08215 b099e32e46af217492d5a121a8d5e087 706 Pfam PF00013 KH domain 555 612 6.8E-13 T 11-11-2016 IPR004088 K Homology domain, type 1 GO:0003723 AUP74_RS08215 b099e32e46af217492d5a121a8d5e087 706 SUPERFAMILY SSF55666 144 235 8.84E-28 T 11-11-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AUP74_RS08215 b099e32e46af217492d5a121a8d5e087 706 SUPERFAMILY SSF54211 4 143 3.85E-51 T 11-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold AUP74_RS08215 b099e32e46af217492d5a121a8d5e087 706 Gene3D G3DSA:3.30.230.70 313 541 1.4E-87 T 11-11-2016 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AUP74_RS08215 b099e32e46af217492d5a121a8d5e087 706 Gene3D G3DSA:3.30.230.70 3 224 6.5E-83 T 11-11-2016 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AUP74_RS08215 b099e32e46af217492d5a121a8d5e087 706 SUPERFAMILY SSF55666 448 544 7.15E-29 T 11-11-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AUP74_RS08215 b099e32e46af217492d5a121a8d5e087 706 SUPERFAMILY SSF54791 553 638 3.45E-24 T 11-11-2016 IPR004088 K Homology domain, type 1 GO:0003723 AUP74_RS08215 b099e32e46af217492d5a121a8d5e087 706 SUPERFAMILY SSF54211 290 486 1.32E-47 T 11-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold AUP74_RS08215 b099e32e46af217492d5a121a8d5e087 706 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 2 691 30.741 T 11-11-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 AUP74_RS02765 341ad2df8cf73e853e917e66d14da129 481 Gene3D G3DSA:3.40.309.10 267 452 8.9E-69 T 11-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 AUP74_RS02765 341ad2df8cf73e853e917e66d14da129 481 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 253 260 - T 11-11-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 AUP74_RS02765 341ad2df8cf73e853e917e66d14da129 481 SUPERFAMILY SSF53720 5 480 3.14E-171 T 11-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AUP74_RS02765 341ad2df8cf73e853e917e66d14da129 481 Pfam PF00171 Aldehyde dehydrogenase family 19 475 4.9E-169 T 11-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 AUP74_RS02765 341ad2df8cf73e853e917e66d14da129 481 Gene3D G3DSA:3.40.605.10 9 266 3.8E-103 T 11-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AUP74_RS12615 4b3333d11e77bc7f8a039eb8006bf794 161 Gene3D G3DSA:3.40.50.1450 5 146 3.1E-21 T 11-11-2016 IPR023430 Peptidase HybD-like domain AUP74_RS12615 4b3333d11e77bc7f8a039eb8006bf794 161 SUPERFAMILY SSF53163 4 146 5.23E-22 T 11-11-2016 IPR023430 Peptidase HybD-like domain AUP74_RS12615 4b3333d11e77bc7f8a039eb8006bf794 161 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 6 146 4.4E-23 T 11-11-2016 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AUP74_RS12615 4b3333d11e77bc7f8a039eb8006bf794 161 Pfam PF01750 Hydrogenase maturation protease 34 146 1.1E-4 T 11-11-2016 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AUP74_RS00420 58e7a227060e609bab71198684beaf22 175 Hamap MF_01186 LPS-assembly lipoprotein LptE [lptE]. 6 166 18.767 T 11-11-2016 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 AUP74_RS00420 58e7a227060e609bab71198684beaf22 175 Pfam PF04390 Lipopolysaccharide-assembly 12 161 1.3E-14 T 11-11-2016 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 AUP74_RS00420 58e7a227060e609bab71198684beaf22 175 Gene3D G3DSA:3.30.160.150 21 167 1.5E-34 T 11-11-2016 AUP74_RS01625 ea0e289dc92d8fe494b5101d2738554f 368 Gene3D G3DSA:1.10.12.10 283 339 4.9E-4 T 11-11-2016 IPR014748 Crontonase, C-terminal AUP74_RS01625 ea0e289dc92d8fe494b5101d2738554f 368 Gene3D G3DSA:3.90.226.10 4 204 8.7E-53 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS01625 ea0e289dc92d8fe494b5101d2738554f 368 SUPERFAMILY SSF52096 4 193 3.61E-66 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS01625 ea0e289dc92d8fe494b5101d2738554f 368 SUPERFAMILY SSF52096 265 341 3.61E-66 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS01625 ea0e289dc92d8fe494b5101d2738554f 368 Pfam PF16113 Enoyl-CoA hydratase/isomerase 16 355 1.4E-115 T 11-11-2016 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 AUP74_RS10240 f2b838b1267b941dec64c521abbf5400 164 Pfam PF02631 RecX family 36 155 4.8E-32 T 11-11-2016 IPR003783 Regulatory protein RecX GO:0006282 AUP74_RS10240 f2b838b1267b941dec64c521abbf5400 164 Gene3D G3DSA:1.10.10.10 11 55 5.3E-10 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS10240 f2b838b1267b941dec64c521abbf5400 164 Hamap MF_01114 Regulatory protein RecX [recX]. 3 160 14.689 T 11-11-2016 IPR003783 Regulatory protein RecX GO:0006282 AUP74_RS10240 f2b838b1267b941dec64c521abbf5400 164 Gene3D G3DSA:1.10.10.10 56 100 4.4E-20 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS10240 f2b838b1267b941dec64c521abbf5400 164 Gene3D G3DSA:1.10.10.10 102 155 5.4E-15 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS01630 db36175072cb69258e9e4a9cb98babf5 554 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AUP74_RS01630 db36175072cb69258e9e4a9cb98babf5 554 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 3 552 4.5E-295 T 11-11-2016 IPR022374 ABC transporter, ATP-binding protein, ChvD AUP74_RS01630 db36175072cb69258e9e4a9cb98babf5 554 Pfam PF00005 ABC transporter 340 473 2.0E-23 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AUP74_RS01630 db36175072cb69258e9e4a9cb98babf5 554 Pfam PF00005 ABC transporter 22 191 4.2E-29 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AUP74_RS01630 db36175072cb69258e9e4a9cb98babf5 554 Gene3D G3DSA:3.40.50.300 322 534 4.1E-45 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS01630 db36175072cb69258e9e4a9cb98babf5 554 SMART SM00382 348 526 8.3E-7 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS01630 db36175072cb69258e9e4a9cb98babf5 554 SMART SM00382 31 236 1.2E-7 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS01630 db36175072cb69258e9e4a9cb98babf5 554 SUPERFAMILY SSF52540 12 243 1.31E-50 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS01630 db36175072cb69258e9e4a9cb98babf5 554 Pfam PF12848 ABC transporter 230 303 4.0E-11 T 11-11-2016 IPR032781 ABC-transporter extension domain AUP74_RS01630 db36175072cb69258e9e4a9cb98babf5 554 Gene3D G3DSA:3.40.50.300 10 109 4.1E-52 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS01630 db36175072cb69258e9e4a9cb98babf5 554 Gene3D G3DSA:3.40.50.300 141 288 4.1E-52 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS01630 db36175072cb69258e9e4a9cb98babf5 554 SUPERFAMILY SSF52540 296 533 5.06E-45 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS07490 ebaa9f10009610a43b7f80b7e2bd04f3 691 Gene3D G3DSA:3.40.390.10 478 691 2.7E-111 T 11-11-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 AUP74_RS07490 ebaa9f10009610a43b7f80b7e2bd04f3 691 Gene3D G3DSA:3.40.390.10 317 438 2.7E-111 T 11-11-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 AUP74_RS07490 ebaa9f10009610a43b7f80b7e2bd04f3 691 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 589 600 6.3E-21 T 11-11-2016 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 AUP74_RS07490 ebaa9f10009610a43b7f80b7e2bd04f3 691 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 497 509 6.3E-21 T 11-11-2016 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 AUP74_RS07490 ebaa9f10009610a43b7f80b7e2bd04f3 691 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 518 534 6.3E-21 T 11-11-2016 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 AUP74_RS07490 ebaa9f10009610a43b7f80b7e2bd04f3 691 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 479 491 6.3E-21 T 11-11-2016 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 AUP74_RS07490 ebaa9f10009610a43b7f80b7e2bd04f3 691 Pfam PF01431 Peptidase family M13 487 688 2.3E-74 T 11-11-2016 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 AUP74_RS07490 ebaa9f10009610a43b7f80b7e2bd04f3 691 Pfam PF05649 Peptidase family M13 60 435 3.0E-100 T 11-11-2016 IPR008753 Peptidase M13, N-terminal domain GO:0006508 AUP74_RS07490 ebaa9f10009610a43b7f80b7e2bd04f3 691 SUPERFAMILY SSF55486 48 691 4.98E-217 T 11-11-2016 AUP74_RS14310 0caf958116243380800020668638a97c 457 Pfam PF03209 PUCC protein 31 437 1.1E-64 T 11-11-2016 IPR004896 PucC-related AUP74_RS14310 0caf958116243380800020668638a97c 457 Gene3D G3DSA:1.20.1250.20 20 214 6.5E-10 T 11-11-2016 AUP74_RS14310 0caf958116243380800020668638a97c 457 Gene3D G3DSA:1.20.1250.20 235 438 1.7E-12 T 11-11-2016 AUP74_RS14310 0caf958116243380800020668638a97c 457 SUPERFAMILY SSF103473 21 437 2.49E-31 T 11-11-2016 IPR020846 Major facilitator superfamily domain AUP74_RS15385 80a259446c6e7bdd75c79887e3e8a3b4 601 SUPERFAMILY SSF50447 186 284 1.41E-21 T 11-11-2016 IPR009000 Translation protein, beta-barrel domain AUP74_RS15385 80a259446c6e7bdd75c79887e3e8a3b4 601 Gene3D G3DSA:3.30.70.240 406 494 6.2E-23 T 11-11-2016 IPR000640 Translation elongation factor EFG, V domain AUP74_RS15385 80a259446c6e7bdd75c79887e3e8a3b4 601 Hamap MF_00071 Elongation factor 4 [lepA]. 1 601 302.386 T 11-11-2016 IPR006297 Elongation factor 4 GO:0005525 AUP74_RS15385 80a259446c6e7bdd75c79887e3e8a3b4 601 SUPERFAMILY SSF54980 297 375 7.19E-19 T 11-11-2016 IPR009022 Elongation factor G, III-V domain AUP74_RS15385 80a259446c6e7bdd75c79887e3e8a3b4 601 Pfam PF00009 Elongation factor Tu GTP binding domain 7 185 2.0E-51 T 11-11-2016 AUP74_RS15385 80a259446c6e7bdd75c79887e3e8a3b4 601 TIGRFAM TIGR01393 lepA: elongation factor 4 7 600 4.3E-295 T 11-11-2016 IPR006297 Elongation factor 4 GO:0005525 AUP74_RS15385 80a259446c6e7bdd75c79887e3e8a3b4 601 Gene3D G3DSA:3.30.70.870 296 374 3.0E-26 T 11-11-2016 AUP74_RS15385 80a259446c6e7bdd75c79887e3e8a3b4 601 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 46 61 - T 11-11-2016 IPR031157 Tr-type G domain, conserved site AUP74_RS15385 80a259446c6e7bdd75c79887e3e8a3b4 601 Pfam PF00679 Elongation factor G C-terminus 404 489 2.4E-21 T 11-11-2016 IPR000640 Translation elongation factor EFG, V domain AUP74_RS15385 80a259446c6e7bdd75c79887e3e8a3b4 601 Gene3D G3DSA:3.40.50.300 5 196 5.2E-59 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS15385 80a259446c6e7bdd75c79887e3e8a3b4 601 PRINTS PR00315 GTP-binding elongation factor signature 53 61 1.7E-14 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AUP74_RS15385 80a259446c6e7bdd75c79887e3e8a3b4 601 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.7E-14 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AUP74_RS15385 80a259446c6e7bdd75c79887e3e8a3b4 601 PRINTS PR00315 GTP-binding elongation factor signature 10 23 1.7E-14 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AUP74_RS15385 80a259446c6e7bdd75c79887e3e8a3b4 601 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.7E-14 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AUP74_RS15385 80a259446c6e7bdd75c79887e3e8a3b4 601 PRINTS PR00315 GTP-binding elongation factor signature 130 139 1.7E-14 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AUP74_RS15385 80a259446c6e7bdd75c79887e3e8a3b4 601 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 154 2.8E-17 T 11-11-2016 IPR005225 Small GTP-binding protein domain GO:0005525 AUP74_RS15385 80a259446c6e7bdd75c79887e3e8a3b4 601 SUPERFAMILY SSF52540 6 209 5.57E-54 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS15385 80a259446c6e7bdd75c79887e3e8a3b4 601 Gene3D G3DSA:2.40.30.10 197 286 9.9E-20 T 11-11-2016 AUP74_RS15385 80a259446c6e7bdd75c79887e3e8a3b4 601 Pfam PF06421 GTP-binding protein LepA C-terminus 492 598 2.6E-49 T 11-11-2016 IPR013842 GTP-binding protein LepA, C-terminal AUP74_RS15385 80a259446c6e7bdd75c79887e3e8a3b4 601 SMART SM00838 406 490 9.4E-4 T 11-11-2016 IPR000640 Translation elongation factor EFG, V domain AUP74_RS15385 80a259446c6e7bdd75c79887e3e8a3b4 601 SUPERFAMILY SSF54980 405 498 9.59E-26 T 11-11-2016 IPR009022 Elongation factor G, III-V domain AUP74_RS15950 eceb5ebb9ed74d54da5cb41709d722ef 224 SMART SM00448 1 112 4.4E-43 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS15950 eceb5ebb9ed74d54da5cb41709d722ef 224 Gene3D G3DSA:1.10.10.10 123 222 4.2E-29 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS15950 eceb5ebb9ed74d54da5cb41709d722ef 224 Pfam PF00072 Response regulator receiver domain 4 112 5.7E-28 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS15950 eceb5ebb9ed74d54da5cb41709d722ef 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 220 2.9E-21 T 11-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AUP74_RS15950 eceb5ebb9ed74d54da5cb41709d722ef 224 Gene3D G3DSA:3.40.50.2300 1 120 2.1E-38 T 11-11-2016 AUP74_RS15950 eceb5ebb9ed74d54da5cb41709d722ef 224 SMART SM00862 145 220 3.9E-22 T 11-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AUP74_RS15950 eceb5ebb9ed74d54da5cb41709d722ef 224 SUPERFAMILY SSF52172 1 175 1.76E-40 T 11-11-2016 IPR011006 CheY-like superfamily AUP74_RS07915 7d46bcac9301ffe68ef8d016ae4beef5 91 Pfam PF09723 Zinc ribbon domain 1 41 7.2E-18 T 11-11-2016 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain AUP74_RS07915 7d46bcac9301ffe68ef8d016ae4beef5 91 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 52 8.1E-24 T 11-11-2016 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain AUP74_RS07915 7d46bcac9301ffe68ef8d016ae4beef5 91 SMART SM00834 1 42 5.5E-22 T 11-11-2016 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain AUP74_RS13695 023cac13ed4e408d9a60375eee1b83ce 307 Pfam PF00892 EamA-like transporter family 8 145 5.6E-18 T 11-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 AUP74_RS13695 023cac13ed4e408d9a60375eee1b83ce 307 Pfam PF00892 EamA-like transporter family 158 288 9.8E-14 T 11-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 AUP74_RS13695 023cac13ed4e408d9a60375eee1b83ce 307 SUPERFAMILY SSF103481 46 147 5.36E-12 T 11-11-2016 AUP74_RS13695 023cac13ed4e408d9a60375eee1b83ce 307 SUPERFAMILY SSF103481 192 288 4.05E-12 T 11-11-2016 AUP74_RS08810 00e514e894497504955eb8b5bde537ee 394 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 39 385 4.9E-124 T 11-11-2016 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AUP74_RS08810 00e514e894497504955eb8b5bde537ee 394 Gene3D G3DSA:3.40.50.2000 228 386 1.6E-63 T 11-11-2016 AUP74_RS08810 00e514e894497504955eb8b5bde537ee 394 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 18 386 1.3E-158 T 11-11-2016 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 KEGG: 00520+5.1.3.14|MetaCyc: PWY-7335 AUP74_RS08810 00e514e894497504955eb8b5bde537ee 394 SUPERFAMILY SSF53756 17 386 1.29E-138 T 11-11-2016 AUP74_RS08810 00e514e894497504955eb8b5bde537ee 394 Gene3D G3DSA:3.40.50.2000 17 227 4.1E-86 T 11-11-2016 AUP74_RS02620 cfe29d180967b7602225b2e7afab0071 399 Gene3D G3DSA:1.20.1250.20 24 201 3.1E-11 T 11-11-2016 AUP74_RS02620 cfe29d180967b7602225b2e7afab0071 399 Gene3D G3DSA:1.20.1250.20 210 384 1.3E-16 T 11-11-2016 AUP74_RS02620 cfe29d180967b7602225b2e7afab0071 399 Pfam PF07690 Major Facilitator Superfamily 28 336 5.4E-11 T 11-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AUP74_RS02620 cfe29d180967b7602225b2e7afab0071 399 SUPERFAMILY SSF103473 23 388 6.02E-34 T 11-11-2016 IPR020846 Major facilitator superfamily domain AUP74_RS03175 11584fa94826641f6d59635cd1a3978e 194 SUPERFAMILY SSF160443 95 177 1.83E-13 T 11-11-2016 IPR002625 Smr domain AUP74_RS03175 11584fa94826641f6d59635cd1a3978e 194 Pfam PF01713 Smr domain 97 177 4.8E-22 T 11-11-2016 IPR002625 Smr domain AUP74_RS03175 11584fa94826641f6d59635cd1a3978e 194 SMART SM00463 94 177 1.3E-9 T 11-11-2016 IPR002625 Smr domain AUP74_RS02140 cfa063251541f5e31e9a1982fa90c963 207 Gene3D G3DSA:3.40.50.1820 8 109 7.6E-20 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS02140 cfa063251541f5e31e9a1982fa90c963 207 Gene3D G3DSA:3.40.50.1820 144 203 7.6E-20 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS02140 cfa063251541f5e31e9a1982fa90c963 207 Pfam PF05728 Uncharacterised protein family (UPF0227) 12 203 2.8E-48 T 11-11-2016 IPR008886 Uncharacterised protein family UPF0227/Esterase YqiA AUP74_RS02140 cfa063251541f5e31e9a1982fa90c963 207 SUPERFAMILY SSF53474 5 204 3.74E-24 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS10955 9295116e18f7da4e76a9b667b6cdc005 411 SUPERFAMILY SSF48452 143 268 6.58E-12 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS10955 9295116e18f7da4e76a9b667b6cdc005 411 TIGRFAM TIGR03142 cytochro_ccmI: cytochrome c-type biogenesis protein CcmI 4 117 1.6E-21 T 11-11-2016 IPR017560 Cytochrome c-type biogenesis protein CcmI AUP74_RS10955 9295116e18f7da4e76a9b667b6cdc005 411 Gene3D G3DSA:1.25.40.10 186 276 1.2E-19 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS09805 b1dbdeedbfb121cd9ec2e4b096ff0272 472 Gene3D G3DSA:2.40.160.60 24 472 3.1E-106 T 11-11-2016 AUP74_RS09805 b1dbdeedbfb121cd9ec2e4b096ff0272 472 SUPERFAMILY SSF56935 25 472 1.69E-79 T 11-11-2016 AUP74_RS09805 b1dbdeedbfb121cd9ec2e4b096ff0272 472 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 18 378 2.0E-77 T 11-11-2016 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) AUP74_RS09805 b1dbdeedbfb121cd9ec2e4b096ff0272 472 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 400 472 5.3E-14 T 11-11-2016 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) AUP74_RS06595 0646d03367850dfb6218f85476d316b8 131 Gene3D G3DSA:1.20.120.550 2 127 2.1E-19 T 11-11-2016 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain AUP74_RS06595 0646d03367850dfb6218f85476d316b8 131 Pfam PF01124 MAPEG family 3 125 6.8E-25 T 11-11-2016 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein AUP74_RS06595 0646d03367850dfb6218f85476d316b8 131 SUPERFAMILY SSF161084 1 123 4.97E-26 T 11-11-2016 AUP74_RS09720 a33ce46cbd2e70037d5b4fc936fb7951 350 SUPERFAMILY SSF50331 242 343 5.02E-7 T 11-11-2016 IPR008995 Molybdate/tungstate binding, C-terminal AUP74_RS09720 a33ce46cbd2e70037d5b4fc936fb7951 350 Pfam PF08402 TOBE domain 283 343 8.3E-5 T 11-11-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 AUP74_RS09720 a33ce46cbd2e70037d5b4fc936fb7951 350 SMART SM00382 30 215 1.3E-16 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS09720 a33ce46cbd2e70037d5b4fc936fb7951 350 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AUP74_RS09720 a33ce46cbd2e70037d5b4fc936fb7951 350 SUPERFAMILY SSF52540 6 246 1.69E-74 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS09720 a33ce46cbd2e70037d5b4fc936fb7951 350 Gene3D G3DSA:3.40.50.300 3 237 7.5E-69 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS09720 a33ce46cbd2e70037d5b4fc936fb7951 350 Pfam PF00005 ABC transporter 21 165 3.1E-34 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AUP74_RS02990 9e71e9f34c4796e0f7cd1f13cd3ec6e9 406 Gene3D G3DSA:3.30.300.10 246 404 6.6E-68 T 11-11-2016 AUP74_RS02990 9e71e9f34c4796e0f7cd1f13cd3ec6e9 406 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 6 101 5.8E-40 T 11-11-2016 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AUP74_RS02990 9e71e9f34c4796e0f7cd1f13cd3ec6e9 406 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 6 374 1.6E-181 T 11-11-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AUP74_RS02990 9e71e9f34c4796e0f7cd1f13cd3ec6e9 406 Pfam PF02772 S-adenosylmethionine synthetase, central domain 115 233 6.0E-44 T 11-11-2016 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AUP74_RS02990 9e71e9f34c4796e0f7cd1f13cd3ec6e9 406 SUPERFAMILY SSF55973 5 110 7.06E-45 T 11-11-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AUP74_RS02990 9e71e9f34c4796e0f7cd1f13cd3ec6e9 406 SUPERFAMILY SSF55973 235 399 9.03E-65 T 11-11-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AUP74_RS02990 9e71e9f34c4796e0f7cd1f13cd3ec6e9 406 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 117 127 - T 11-11-2016 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AUP74_RS02990 9e71e9f34c4796e0f7cd1f13cd3ec6e9 406 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 261 269 - T 11-11-2016 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AUP74_RS02990 9e71e9f34c4796e0f7cd1f13cd3ec6e9 406 Gene3D G3DSA:3.30.300.10 12 136 1.9E-46 T 11-11-2016 AUP74_RS02990 9e71e9f34c4796e0f7cd1f13cd3ec6e9 406 SUPERFAMILY SSF55973 112 234 7.85E-51 T 11-11-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AUP74_RS02990 9e71e9f34c4796e0f7cd1f13cd3ec6e9 406 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 235 368 8.8E-66 T 11-11-2016 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AUP74_RS02990 9e71e9f34c4796e0f7cd1f13cd3ec6e9 406 Gene3D G3DSA:3.30.300.10 137 235 1.0E-42 T 11-11-2016 AUP74_RS02990 9e71e9f34c4796e0f7cd1f13cd3ec6e9 406 PIRSF PIRSF000497 1 405 1.2E-169 T 11-11-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AUP74_RS02990 9e71e9f34c4796e0f7cd1f13cd3ec6e9 406 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 3 404 56.701 T 11-11-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AUP74_RS04700 f8d281bde21fec4d6771caf271200c32 296 Gene3D G3DSA:1.10.287.70 3 67 4.9E-15 T 11-11-2016 AUP74_RS04700 f8d281bde21fec4d6771caf271200c32 296 SUPERFAMILY SSF81452 5 295 1.47E-76 T 11-11-2016 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS04700 f8d281bde21fec4d6771caf271200c32 296 Pfam PF00510 Cytochrome c oxidase subunit III 152 295 8.2E-40 T 11-11-2016 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS04700 f8d281bde21fec4d6771caf271200c32 296 Pfam PF00510 Cytochrome c oxidase subunit III 6 101 8.2E-9 T 11-11-2016 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS04700 f8d281bde21fec4d6771caf271200c32 296 Gene3D G3DSA:1.20.120.80 146 295 1.6E-64 T 11-11-2016 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS04700 f8d281bde21fec4d6771caf271200c32 296 Gene3D G3DSA:1.20.120.80 71 113 1.6E-64 T 11-11-2016 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS15660 948a86385e6aaaf691e8747608a1ca00 256 PRINTS PR00599 Methionine aminopeptidase-1 signature 69 82 9.9E-23 T 11-11-2016 IPR001714 Peptidase M24, methionine aminopeptidase AUP74_RS15660 948a86385e6aaaf691e8747608a1ca00 256 PRINTS PR00599 Methionine aminopeptidase-1 signature 162 174 9.9E-23 T 11-11-2016 IPR001714 Peptidase M24, methionine aminopeptidase AUP74_RS15660 948a86385e6aaaf691e8747608a1ca00 256 PRINTS PR00599 Methionine aminopeptidase-1 signature 92 108 9.9E-23 T 11-11-2016 IPR001714 Peptidase M24, methionine aminopeptidase AUP74_RS15660 948a86385e6aaaf691e8747608a1ca00 256 PRINTS PR00599 Methionine aminopeptidase-1 signature 193 205 9.9E-23 T 11-11-2016 IPR001714 Peptidase M24, methionine aminopeptidase AUP74_RS15660 948a86385e6aaaf691e8747608a1ca00 256 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 168 186 - T 11-11-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 AUP74_RS15660 948a86385e6aaaf691e8747608a1ca00 256 Gene3D G3DSA:3.90.230.10 4 254 5.7E-100 T 11-11-2016 IPR000994 Peptidase M24, structural domain AUP74_RS15660 948a86385e6aaaf691e8747608a1ca00 256 SUPERFAMILY SSF55920 4 253 1.83E-90 T 11-11-2016 IPR000994 Peptidase M24, structural domain AUP74_RS15660 948a86385e6aaaf691e8747608a1ca00 256 Pfam PF00557 Metallopeptidase family M24 12 242 7.9E-54 T 11-11-2016 IPR000994 Peptidase M24, structural domain AUP74_RS15660 948a86385e6aaaf691e8747608a1ca00 256 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 4 250 6.2E-102 T 11-11-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 AUP74_RS15660 948a86385e6aaaf691e8747608a1ca00 256 Hamap MF_01974 Methionine aminopeptidase [map]. 3 251 42.962 T 11-11-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 AUP74_RS10375 364a59d6a8a32e4010392673ab8e3571 223 SUPERFAMILY SSF143081 14 186 7.33E-22 T 11-11-2016 IPR003738 SOS response associated peptidase (SRAP) AUP74_RS10375 364a59d6a8a32e4010392673ab8e3571 223 Gene3D G3DSA:3.90.1680.10 21 178 1.4E-13 T 11-11-2016 IPR003738 SOS response associated peptidase (SRAP) AUP74_RS10375 364a59d6a8a32e4010392673ab8e3571 223 Pfam PF02586 SOS response associated peptidase (SRAP) 30 177 7.0E-12 T 11-11-2016 IPR003738 SOS response associated peptidase (SRAP) AUP74_RS06145 f3766131496baf1d02336c26c847af95 133 Pfam PF06610 L-alanine exporter 4 119 3.0E-30 T 11-11-2016 IPR010574 L-alanine exporter AlaE GO:0016021|GO:0034639 AUP74_RS06145 f3766131496baf1d02336c26c847af95 133 ProDom PD090021 MEMBRANE YGAW TRANSMEMBRANE INNER VV2263 Y3636 VC1828 VP1070 4 117 2.0E-17 T 11-11-2016 IPR010574 L-alanine exporter AlaE GO:0016021|GO:0034639 AUP74_RS08305 348921619d0dc5ccad39fa6f74a007b7 294 Hamap MF_00188 Protease HtpX [htpX]. 1 292 23.746 T 11-11-2016 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 AUP74_RS08305 348921619d0dc5ccad39fa6f74a007b7 294 Gene3D G3DSA:3.30.2010.10 77 164 1.5E-28 T 11-11-2016 AUP74_RS08305 348921619d0dc5ccad39fa6f74a007b7 294 Pfam PF01435 Peptidase family M48 81 291 1.5E-37 T 11-11-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 AUP74_RS16120 c7b4eec028f5ff0f66814af75bd95016 215 SUPERFAMILY SSF52016 1 205 1.79E-62 T 11-11-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel AUP74_RS16120 c7b4eec028f5ff0f66814af75bd95016 215 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 196 3.7E-83 T 11-11-2016 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 AUP74_RS16120 c7b4eec028f5ff0f66814af75bd95016 215 Gene3D G3DSA:3.20.19.10 1 203 2.7E-49 T 11-11-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel AUP74_RS16120 c7b4eec028f5ff0f66814af75bd95016 215 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 210 43.716 T 11-11-2016 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 AUP74_RS16120 c7b4eec028f5ff0f66814af75bd95016 215 Pfam PF00694 Aconitase C-terminal domain 1 132 7.4E-36 T 11-11-2016 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS12335 7aec499c267631b3fe77646f885468d8 142 Pfam PF08334 Type II secretion system (T2SS), protein G 32 137 3.4E-40 T 11-11-2016 IPR013545 Type II secretion system protein G AUP74_RS12335 7aec499c267631b3fe77646f885468d8 142 PRINTS PR00813 Bacterial general secretion pathway protein G signature 45 63 3.1E-20 T 11-11-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 AUP74_RS12335 7aec499c267631b3fe77646f885468d8 142 PRINTS PR00813 Bacterial general secretion pathway protein G signature 9 34 3.1E-20 T 11-11-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 AUP74_RS12335 7aec499c267631b3fe77646f885468d8 142 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 9 29 1.6E-6 T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS12335 7aec499c267631b3fe77646f885468d8 142 SUPERFAMILY SSF54523 36 137 1.57E-36 T 11-11-2016 AUP74_RS12335 7aec499c267631b3fe77646f885468d8 142 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 5 28 5.0E-7 T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS12335 7aec499c267631b3fe77646f885468d8 142 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 8 28 - T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS12335 7aec499c267631b3fe77646f885468d8 142 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 9 137 9.4E-56 T 11-11-2016 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 AUP74_RS12335 7aec499c267631b3fe77646f885468d8 142 Gene3D G3DSA:3.30.700.10 10 74 3.0E-9 T 11-11-2016 AUP74_RS02060 56a4a143783e4b4f5f56d0c3c236b1e6 283 Pfam PF00756 Putative esterase 47 272 1.4E-29 T 11-11-2016 IPR000801 Putative esterase Reactome: R-HSA-156590 AUP74_RS02060 56a4a143783e4b4f5f56d0c3c236b1e6 283 SUPERFAMILY SSF53474 42 277 8.46E-47 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS02060 56a4a143783e4b4f5f56d0c3c236b1e6 283 Gene3D G3DSA:3.40.50.1820 45 277 9.2E-55 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS04015 d1d497c87b0bc9d3fb18104e24afc764 203 Hamap MF_01839 Nucleoid occlusion factor SlmA [slmA]. 1 194 37.545 T 11-11-2016 IPR023769 Nucleoid occlusion factor SlmA GO:0010974 AUP74_RS04015 d1d497c87b0bc9d3fb18104e24afc764 203 SUPERFAMILY SSF48498 79 193 1.37E-10 T 11-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AUP74_RS04015 d1d497c87b0bc9d3fb18104e24afc764 203 SUPERFAMILY SSF46689 3 71 8.03E-13 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS04015 d1d497c87b0bc9d3fb18104e24afc764 203 Gene3D G3DSA:1.10.357.10 4 197 5.5E-39 T 11-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 AUP74_RS04015 d1d497c87b0bc9d3fb18104e24afc764 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 56 8.9E-9 T 11-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AUP74_RS13150 94a9fbf8571f9dc679eb808822e839e4 821 SUPERFAMILY SSF56219 541 806 9.55E-42 T 11-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase AUP74_RS13150 94a9fbf8571f9dc679eb808822e839e4 821 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 256 318 7.5E-6 T 11-11-2016 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 AUP74_RS13150 94a9fbf8571f9dc679eb808822e839e4 821 Gene3D G3DSA:3.40.720.10 257 315 1.7E-5 T 11-11-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 AUP74_RS13150 94a9fbf8571f9dc679eb808822e839e4 821 Gene3D G3DSA:3.40.720.10 28 118 3.0E-6 T 11-11-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 AUP74_RS13150 94a9fbf8571f9dc679eb808822e839e4 821 Gene3D G3DSA:3.60.10.10 556 801 1.3E-20 T 11-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase AUP74_RS13150 94a9fbf8571f9dc679eb808822e839e4 821 SUPERFAMILY SSF53649 234 311 3.71E-16 T 11-11-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 AUP74_RS13150 94a9fbf8571f9dc679eb808822e839e4 821 SUPERFAMILY SSF53649 34 193 3.71E-16 T 11-11-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 AUP74_RS13150 94a9fbf8571f9dc679eb808822e839e4 821 SUPERFAMILY SSF53649 341 464 3.71E-16 T 11-11-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 AUP74_RS13150 94a9fbf8571f9dc679eb808822e839e4 821 SUPERFAMILY SSF53649 493 511 3.71E-16 T 11-11-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 AUP74_RS13150 94a9fbf8571f9dc679eb808822e839e4 821 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 558 793 1.4E-20 T 11-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase AUP74_RS00385 df0c5578fcddbe607550dd07665775c8 145 Gene3D G3DSA:2.40.160.20 42 143 1.9E-7 T 11-11-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AUP74_RS00385 df0c5578fcddbe607550dd07665775c8 145 Pfam PF09411 Lipid A 3-O-deacylase (PagL) 90 143 2.8E-5 T 11-11-2016 IPR018550 Lipid A 3-O-deacylase-related AUP74_RS00260 80246d2126612f03dcc09c95c1a63d98 207 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 7 204 2.5E-79 T 11-11-2016 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 AUP74_RS00260 80246d2126612f03dcc09c95c1a63d98 207 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 37 46 - T 11-11-2016 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 AUP74_RS00260 80246d2126612f03dcc09c95c1a63d98 207 Pfam PF01081 KDPG and KHG aldolase 7 200 2.0E-72 T 11-11-2016 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 AUP74_RS00260 80246d2126612f03dcc09c95c1a63d98 207 SUPERFAMILY SSF51569 3 204 1.26E-66 T 11-11-2016 AUP74_RS00260 80246d2126612f03dcc09c95c1a63d98 207 Gene3D G3DSA:3.20.20.70 2 204 1.5E-75 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS08220 9a9d7164246ee0f3436b2d7ccd6c6bca 989 SUPERFAMILY SSF49452 33 120 4.51E-12 T 11-11-2016 IPR013784 Carbohydrate-binding-like fold GO:0030246 AUP74_RS08220 9a9d7164246ee0f3436b2d7ccd6c6bca 989 Gene3D G3DSA:2.60.40.1120 40 134 3.4E-12 T 11-11-2016 IPR014766 Carboxypeptidase, regulatory domain AUP74_RS08220 9a9d7164246ee0f3436b2d7ccd6c6bca 989 Pfam PF13620 Carboxypeptidase regulatory-like domain 40 119 1.9E-11 T 11-11-2016 AUP74_RS08220 9a9d7164246ee0f3436b2d7ccd6c6bca 989 SUPERFAMILY SSF56935 694 738 1.19E-43 T 11-11-2016 AUP74_RS08220 9a9d7164246ee0f3436b2d7ccd6c6bca 989 SUPERFAMILY SSF56935 853 989 1.19E-43 T 11-11-2016 AUP74_RS08220 9a9d7164246ee0f3436b2d7ccd6c6bca 989 SUPERFAMILY SSF56935 779 823 1.19E-43 T 11-11-2016 AUP74_RS08220 9a9d7164246ee0f3436b2d7ccd6c6bca 989 SUPERFAMILY SSF56935 456 658 1.19E-43 T 11-11-2016 AUP74_RS08220 9a9d7164246ee0f3436b2d7ccd6c6bca 989 SUPERFAMILY SSF56935 124 422 1.19E-43 T 11-11-2016 AUP74_RS06900 b769e35671392e4c545724b019bfa51c 177 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 1.3E-73 T 11-11-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 AUP74_RS06900 b769e35671392e4c545724b019bfa51c 177 SUPERFAMILY SSF56053 1 82 1.7E-23 T 11-11-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06900 b769e35671392e4c545724b019bfa51c 177 PRINTS PR00059 Ribosomal protein L6 signature 99 115 2.3E-33 T 11-11-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 AUP74_RS06900 b769e35671392e4c545724b019bfa51c 177 PRINTS PR00059 Ribosomal protein L6 signature 141 162 2.3E-33 T 11-11-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 AUP74_RS06900 b769e35671392e4c545724b019bfa51c 177 PRINTS PR00059 Ribosomal protein L6 signature 71 96 2.3E-33 T 11-11-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 AUP74_RS06900 b769e35671392e4c545724b019bfa51c 177 PIRSF PIRSF002162 1 177 6.9E-45 T 11-11-2016 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06900 b769e35671392e4c545724b019bfa51c 177 Gene3D G3DSA:3.90.930.12 2 82 1.3E-28 T 11-11-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06900 b769e35671392e4c545724b019bfa51c 177 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 36.343 T 11-11-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 AUP74_RS06900 b769e35671392e4c545724b019bfa51c 177 Pfam PF00347 Ribosomal protein L6 91 164 3.6E-17 T 11-11-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06900 b769e35671392e4c545724b019bfa51c 177 Pfam PF00347 Ribosomal protein L6 11 82 2.3E-18 T 11-11-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06900 b769e35671392e4c545724b019bfa51c 177 SUPERFAMILY SSF56053 83 177 3.4E-34 T 11-11-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06900 b769e35671392e4c545724b019bfa51c 177 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 11-11-2016 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS06900 b769e35671392e4c545724b019bfa51c 177 Gene3D G3DSA:3.90.930.12 83 177 4.0E-39 T 11-11-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS14715 60bf9d9e05cd74861e94d8c7c7c28739 337 SUPERFAMILY SSF46589 13 99 8.89E-24 T 11-11-2016 IPR010978 tRNA-binding arm GO:0000166 AUP74_RS14715 60bf9d9e05cd74861e94d8c7c7c28739 337 Pfam PF01409 tRNA synthetases class II core domain (F) 92 337 2.3E-108 T 11-11-2016 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 AUP74_RS14715 60bf9d9e05cd74861e94d8c7c7c28739 337 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 21 87 3.0E-27 T 11-11-2016 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 AUP74_RS14715 60bf9d9e05cd74861e94d8c7c7c28739 337 Gene3D G3DSA:3.30.930.10 9 337 1.9E-135 T 11-11-2016 AUP74_RS14715 60bf9d9e05cd74861e94d8c7c7c28739 337 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 38 337 2.0E-109 T 11-11-2016 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 AUP74_RS14715 60bf9d9e05cd74861e94d8c7c7c28739 337 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 8 337 50.547 T 11-11-2016 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 AUP74_RS14715 60bf9d9e05cd74861e94d8c7c7c28739 337 SUPERFAMILY SSF55681 92 337 9.23E-82 T 11-11-2016 AUP74_RS01125 b606c512e8d98019b75d4dd62cb8f8a3 151 PIRSF PIRSF001338 1 151 3.5E-62 T 11-11-2016 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 AUP74_RS01125 b606c512e8d98019b75d4dd62cb8f8a3 151 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 1 150 27.818 T 11-11-2016 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AUP74_RS01125 b606c512e8d98019b75d4dd62cb8f8a3 151 Pfam PF00731 AIR carboxylase 1 143 1.2E-60 T 11-11-2016 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AUP74_RS01125 b606c512e8d98019b75d4dd62cb8f8a3 151 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 1 146 4.3E-59 T 11-11-2016 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AUP74_RS01125 b606c512e8d98019b75d4dd62cb8f8a3 151 SUPERFAMILY SSF52255 1 146 3.27E-60 T 11-11-2016 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AUP74_RS01125 b606c512e8d98019b75d4dd62cb8f8a3 151 SMART SM01001 1 146 4.6E-88 T 11-11-2016 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AUP74_RS01125 b606c512e8d98019b75d4dd62cb8f8a3 151 Gene3D G3DSA:3.40.50.7700 1 146 7.6E-68 T 11-11-2016 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AUP74_RS07890 df80b46713d2541b0e3c361916180d40 262 Pfam PF04116 Fatty acid hydroxylase superfamily 99 232 4.2E-27 T 11-11-2016 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0006633|GO:0016491|GO:0055114 AUP74_RS03975 4848dea7b3cd41e955a905ff46c9c9c4 306 Pfam PF07969 Amidohydrolase family 92 234 3.5E-17 T 11-11-2016 IPR013108 Amidohydrolase 3 AUP74_RS03975 4848dea7b3cd41e955a905ff46c9c9c4 306 Gene3D G3DSA:2.30.40.10 40 145 4.4E-13 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS03975 4848dea7b3cd41e955a905ff46c9c9c4 306 SUPERFAMILY SSF51338 255 298 1.64E-14 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS03975 4848dea7b3cd41e955a905ff46c9c9c4 306 SUPERFAMILY SSF51338 39 104 1.64E-14 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS12345 afd2400bc7c022cada3e9ae16d44bedc 123 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 5 25 - T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS12345 afd2400bc7c022cada3e9ae16d44bedc 123 Pfam PF02501 Type II secretion system (T2SS), protein I 40 116 1.1E-17 T 11-11-2016 IPR003413 Type II secretion system protein I domain GO:0008565|GO:0015627|GO:0015628 AUP74_RS12345 afd2400bc7c022cada3e9ae16d44bedc 123 Pfam PF13633 Prokaryotic N-terminal methylation site 4 29 1.9E-11 T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS12345 afd2400bc7c022cada3e9ae16d44bedc 123 Gene3D G3DSA:3.30.1300.30 33 118 1.4E-17 T 11-11-2016 AUP74_RS12345 afd2400bc7c022cada3e9ae16d44bedc 123 PRINTS PR00885 Bacterial general secretion pathway protein H signature 2 16 3.1E-5 T 11-11-2016 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 AUP74_RS12345 afd2400bc7c022cada3e9ae16d44bedc 123 PRINTS PR00885 Bacterial general secretion pathway protein H signature 17 31 3.1E-5 T 11-11-2016 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 AUP74_RS12345 afd2400bc7c022cada3e9ae16d44bedc 123 TIGRFAM TIGR01707 gspI: type II secretion system protein I 6 104 2.4E-22 T 11-11-2016 IPR010052 Type II secretion system protein I GO:0008565|GO:0015627|GO:0015628 AUP74_RS12345 afd2400bc7c022cada3e9ae16d44bedc 123 SUPERFAMILY SSF54523 38 116 1.49E-16 T 11-11-2016 AUP74_RS12345 afd2400bc7c022cada3e9ae16d44bedc 123 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 26 8.9E-10 T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS07740 cd341052c9f743b07af6768098584143 294 Pfam PF02798 Glutathione S-transferase, N-terminal domain 65 127 2.1E-6 T 11-11-2016 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 AUP74_RS07740 cd341052c9f743b07af6768098584143 294 Gene3D G3DSA:3.40.30.10 33 130 5.9E-26 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS07740 cd341052c9f743b07af6768098584143 294 Pfam PF13410 Glutathione S-transferase, C-terminal domain 181 243 4.7E-8 T 11-11-2016 AUP74_RS07740 cd341052c9f743b07af6768098584143 294 Gene3D G3DSA:1.20.1050.10 131 254 3.4E-44 T 11-11-2016 IPR010987 Glutathione S-transferase, C-terminal-like AUP74_RS07740 cd341052c9f743b07af6768098584143 294 SUPERFAMILY SSF52833 38 130 8.11E-17 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS07740 cd341052c9f743b07af6768098584143 294 SUPERFAMILY SSF47616 181 259 3.2E-35 T 11-11-2016 IPR010987 Glutathione S-transferase, C-terminal-like AUP74_RS07740 cd341052c9f743b07af6768098584143 294 SUPERFAMILY SSF47616 117 152 3.2E-35 T 11-11-2016 IPR010987 Glutathione S-transferase, C-terminal-like AUP74_RS04105 b47a282a643d0e68c4df3b7b722ea15d 292 Gene3D G3DSA:3.40.50.720 10 245 1.1E-19 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS04105 b47a282a643d0e68c4df3b7b722ea15d 292 SUPERFAMILY SSF51735 5 286 9.47E-29 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS04105 b47a282a643d0e68c4df3b7b722ea15d 292 Pfam PF04321 RmlD substrate binding domain 11 250 4.0E-9 T 11-11-2016 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581 AUP74_RS00775 82ab4b20efe6686f7a0a139d3a5af88d 298 Gene3D G3DSA:3.40.50.620 20 167 7.7E-19 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS00775 82ab4b20efe6686f7a0a139d3a5af88d 298 SUPERFAMILY SSF52402 178 298 3.27E-24 T 11-11-2016 AUP74_RS00775 82ab4b20efe6686f7a0a139d3a5af88d 298 Pfam PF00582 Universal stress protein family 181 298 2.1E-13 T 11-11-2016 IPR006016 UspA GO:0006950 AUP74_RS00775 82ab4b20efe6686f7a0a139d3a5af88d 298 Pfam PF00582 Universal stress protein family 20 172 4.5E-14 T 11-11-2016 IPR006016 UspA GO:0006950 AUP74_RS00775 82ab4b20efe6686f7a0a139d3a5af88d 298 PRINTS PR01438 Universal stress protein signature 179 197 9.7E-10 T 11-11-2016 IPR006015 Universal stress protein A AUP74_RS00775 82ab4b20efe6686f7a0a139d3a5af88d 298 PRINTS PR01438 Universal stress protein signature 276 298 9.7E-10 T 11-11-2016 IPR006015 Universal stress protein A AUP74_RS00775 82ab4b20efe6686f7a0a139d3a5af88d 298 PRINTS PR01438 Universal stress protein signature 258 270 9.7E-10 T 11-11-2016 IPR006015 Universal stress protein A AUP74_RS00775 82ab4b20efe6686f7a0a139d3a5af88d 298 SUPERFAMILY SSF52402 20 173 1.67E-18 T 11-11-2016 AUP74_RS00775 82ab4b20efe6686f7a0a139d3a5af88d 298 Gene3D G3DSA:3.40.50.620 168 298 5.3E-24 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS16895 915914abc4d7d70ecee43d0c42058319 143 Pfam PF14534 Domain of unknown function (DUF4440) 35 132 3.0E-15 T 11-11-2016 IPR027843 Domain of unknown function DUF4440 AUP74_RS16895 915914abc4d7d70ecee43d0c42058319 143 SUPERFAMILY SSF54427 22 142 9.03E-19 T 11-11-2016 IPR032710 NTF2-like domain AUP74_RS16895 915914abc4d7d70ecee43d0c42058319 143 Gene3D G3DSA:3.10.450.50 36 142 8.0E-17 T 11-11-2016 IPR032710 NTF2-like domain AUP74_RS07075 71a0024b027ce932fcd0472c00b0c4a8 329 SMART SM00904 187 320 2.1E-60 T 11-11-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 AUP74_RS07075 71a0024b027ce932fcd0472c00b0c4a8 329 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 24 319 2.2E-93 T 11-11-2016 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AUP74_RS07075 71a0024b027ce932fcd0472c00b0c4a8 329 PIRSF PIRSF004491 6 326 9.3E-101 T 11-11-2016 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AUP74_RS07075 71a0024b027ce932fcd0472c00b0c4a8 329 Pfam PF06574 FAD synthetase 17 171 1.5E-52 T 11-11-2016 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AUP74_RS07075 71a0024b027ce932fcd0472c00b0c4a8 329 SUPERFAMILY SSF82114 178 322 4.14E-40 T 11-11-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 AUP74_RS07075 71a0024b027ce932fcd0472c00b0c4a8 329 Pfam PF01687 Riboflavin kinase 188 319 2.7E-35 T 11-11-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 AUP74_RS07075 71a0024b027ce932fcd0472c00b0c4a8 329 Gene3D G3DSA:3.40.50.620 6 183 1.6E-65 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS07075 71a0024b027ce932fcd0472c00b0c4a8 329 SUPERFAMILY SSF52374 19 179 2.82E-36 T 11-11-2016 AUP74_RS07075 71a0024b027ce932fcd0472c00b0c4a8 329 Gene3D G3DSA:2.40.30.30 184 322 4.7E-36 T 11-11-2016 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 AUP74_RS08780 ffa17e390846fe9ffa09c7820286e784 192 Gene3D G3DSA:3.10.560.10 110 188 1.6E-12 T 11-11-2016 AUP74_RS08780 ffa17e390846fe9ffa09c7820286e784 192 Pfam PF10531 SLBB domain 119 163 8.2E-11 T 11-11-2016 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS08780 ffa17e390846fe9ffa09c7820286e784 192 Gene3D G3DSA:3.30.1950.10 48 109 3.6E-16 T 11-11-2016 AUP74_RS08780 ffa17e390846fe9ffa09c7820286e784 192 Pfam PF02563 Polysaccharide biosynthesis/export protein 41 113 1.2E-16 T 11-11-2016 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 AUP74_RS09505 ec63e8e2a54461d557205318443a4aeb 98 Gene3D G3DSA:1.20.120.20 10 91 5.9E-5 T 11-11-2016 AUP74_RS09505 ec63e8e2a54461d557205318443a4aeb 98 SUPERFAMILY SSF58113 13 98 2.62E-5 T 11-11-2016 AUP74_RS09950 331021670846c62ecca0f5985a2cb7e5 267 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 260 2.2E-16 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AUP74_RS09950 331021670846c62ecca0f5985a2cb7e5 267 SUPERFAMILY SSF161098 71 258 3.14E-34 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AUP74_RS09950 331021670846c62ecca0f5985a2cb7e5 267 Gene3D G3DSA:1.10.3720.10 71 265 1.8E-29 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AUP74_RS09950 331021670846c62ecca0f5985a2cb7e5 267 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 23 265 2.5E-88 T 11-11-2016 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 AUP74_RS09180 b8f8c9c9bd541c70421f1f0fbd0f2d40 465 SUPERFAMILY SSF52540 138 439 5.17E-64 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS09180 b8f8c9c9bd541c70421f1f0fbd0f2d40 465 Pfam PF01926 50S ribosome-binding GTPase 179 297 8.6E-26 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 AUP74_RS09180 b8f8c9c9bd541c70421f1f0fbd0f2d40 465 Pfam PF01926 50S ribosome-binding GTPase 5 119 8.7E-29 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 AUP74_RS09180 b8f8c9c9bd541c70421f1f0fbd0f2d40 465 Gene3D G3DSA:3.40.50.300 174 359 2.3E-54 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS09180 b8f8c9c9bd541c70421f1f0fbd0f2d40 465 Gene3D G3DSA:3.40.50.300 3 170 1.5E-46 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS09180 b8f8c9c9bd541c70421f1f0fbd0f2d40 465 SUPERFAMILY SSF52540 4 167 1.51E-49 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS09180 b8f8c9c9bd541c70421f1f0fbd0f2d40 465 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 177 344 3.9E-26 T 11-11-2016 IPR005225 Small GTP-binding protein domain GO:0005525 AUP74_RS09180 b8f8c9c9bd541c70421f1f0fbd0f2d40 465 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 154 1.2E-23 T 11-11-2016 IPR005225 Small GTP-binding protein domain GO:0005525 AUP74_RS09180 b8f8c9c9bd541c70421f1f0fbd0f2d40 465 Gene3D G3DSA:3.30.300.20 360 434 5.4E-24 T 11-11-2016 IPR015946 K homology domain-like, alpha/beta AUP74_RS09180 b8f8c9c9bd541c70421f1f0fbd0f2d40 465 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 353 433 1.0E-26 T 11-11-2016 IPR032859 GTPase Der, C-terminal KH-domain-like AUP74_RS09180 b8f8c9c9bd541c70421f1f0fbd0f2d40 465 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 3 433 9.4E-178 T 11-11-2016 IPR016484 GTP-binding protein EngA GO:0005525 AUP74_RS09180 b8f8c9c9bd541c70421f1f0fbd0f2d40 465 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 72 90 2.6E-9 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 AUP74_RS09180 b8f8c9c9bd541c70421f1f0fbd0f2d40 465 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 2.6E-9 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 AUP74_RS09180 b8f8c9c9bd541c70421f1f0fbd0f2d40 465 PIRSF PIRSF006485 1 441 1.2E-174 T 11-11-2016 IPR016484 GTP-binding protein EngA GO:0005525 AUP74_RS09180 b8f8c9c9bd541c70421f1f0fbd0f2d40 465 Hamap MF_00195 GTPase Der [der]. 2 436 38.138 T 11-11-2016 IPR016484 GTP-binding protein EngA GO:0005525 AUP74_RS16560 49cec4cfde30df62e24436c9afaa92f8 941 SUPERFAMILY SSF52518 580 797 8.33E-49 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS16560 49cec4cfde30df62e24436c9afaa92f8 941 Pfam PF00676 Dehydrogenase E1 component 217 517 3.8E-51 T 11-11-2016 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 AUP74_RS16560 49cec4cfde30df62e24436c9afaa92f8 941 Pfam PF02779 Transketolase, pyrimidine binding domain 597 790 2.4E-61 T 11-11-2016 IPR005475 Transketolase-like, pyrimidine-binding domain AUP74_RS16560 49cec4cfde30df62e24436c9afaa92f8 941 PIRSF PIRSF000157 1 940 0.0 T 11-11-2016 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 AUP74_RS16560 49cec4cfde30df62e24436c9afaa92f8 941 SUPERFAMILY SSF52518 123 539 5.24E-83 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS16560 49cec4cfde30df62e24436c9afaa92f8 941 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 15 937 0.0 T 11-11-2016 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 AUP74_RS16560 49cec4cfde30df62e24436c9afaa92f8 941 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 12 50 6.9E-17 T 11-11-2016 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 AUP74_RS16560 49cec4cfde30df62e24436c9afaa92f8 941 Gene3D G3DSA:3.40.50.970 597 794 6.8E-22 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS16560 49cec4cfde30df62e24436c9afaa92f8 941 Gene3D G3DSA:3.40.50.970 165 539 5.1E-75 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS16560 49cec4cfde30df62e24436c9afaa92f8 941 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 794 938 8.5E-52 T 11-11-2016 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 AUP74_RS16560 49cec4cfde30df62e24436c9afaa92f8 941 SMART SM00861 597 790 4.6E-59 T 11-11-2016 IPR005475 Transketolase-like, pyrimidine-binding domain AUP74_RS07070 23cea92f8b8f5ea851d31d82bb046cab 543 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 27 531 8.0E-137 T 11-11-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ AUP74_RS07070 23cea92f8b8f5ea851d31d82bb046cab 543 PIRSF PIRSF002869 22 542 4.7E-153 T 11-11-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ AUP74_RS07070 23cea92f8b8f5ea851d31d82bb046cab 543 Pfam PF03023 MviN-like protein 53 503 1.8E-134 T 11-11-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ AUP74_RS07070 23cea92f8b8f5ea851d31d82bb046cab 543 PRINTS PR01806 Virulence factor MviN signature 160 184 4.6E-77 T 11-11-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ AUP74_RS07070 23cea92f8b8f5ea851d31d82bb046cab 543 PRINTS PR01806 Virulence factor MviN signature 76 92 4.6E-77 T 11-11-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ AUP74_RS07070 23cea92f8b8f5ea851d31d82bb046cab 543 PRINTS PR01806 Virulence factor MviN signature 286 312 4.6E-77 T 11-11-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ AUP74_RS07070 23cea92f8b8f5ea851d31d82bb046cab 543 PRINTS PR01806 Virulence factor MviN signature 57 76 4.6E-77 T 11-11-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ AUP74_RS07070 23cea92f8b8f5ea851d31d82bb046cab 543 PRINTS PR01806 Virulence factor MviN signature 384 403 4.6E-77 T 11-11-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ AUP74_RS07070 23cea92f8b8f5ea851d31d82bb046cab 543 PRINTS PR01806 Virulence factor MviN signature 184 205 4.6E-77 T 11-11-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ AUP74_RS07070 23cea92f8b8f5ea851d31d82bb046cab 543 PRINTS PR01806 Virulence factor MviN signature 442 459 4.6E-77 T 11-11-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ AUP74_RS09380 f7a543d51aac89053a9085910b1fdab5 399 Gene3D G3DSA:1.20.1250.20 213 393 3.4E-7 T 11-11-2016 AUP74_RS09380 f7a543d51aac89053a9085910b1fdab5 399 Gene3D G3DSA:1.20.1250.20 10 191 5.0E-27 T 11-11-2016 AUP74_RS09380 f7a543d51aac89053a9085910b1fdab5 399 SUPERFAMILY SSF103473 5 390 2.75E-58 T 11-11-2016 IPR020846 Major facilitator superfamily domain AUP74_RS09380 f7a543d51aac89053a9085910b1fdab5 399 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 7 381 1.3E-88 T 11-11-2016 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 AUP74_RS09380 f7a543d51aac89053a9085910b1fdab5 399 Pfam PF07690 Major Facilitator Superfamily 13 235 7.2E-30 T 11-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AUP74_RS15225 a590a6aea0c8ab4fb852b31f52df1ec5 439 Gene3D G3DSA:1.25.40.10 155 256 6.3E-8 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS15225 a590a6aea0c8ab4fb852b31f52df1ec5 439 Gene3D G3DSA:1.25.40.10 16 27 6.3E-8 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS15225 a590a6aea0c8ab4fb852b31f52df1ec5 439 SUPERFAMILY SSF48452 160 261 3.45E-9 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS06955 48f3553e35d28bb180ab637423edf647 131 Pfam PF01196 Ribosomal protein L17 20 116 3.1E-35 T 11-11-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06955 48f3553e35d28bb180ab637423edf647 131 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 11-11-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06955 48f3553e35d28bb180ab637423edf647 131 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 26.634 T 11-11-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06955 48f3553e35d28bb180ab637423edf647 131 TIGRFAM TIGR00059 L17: ribosomal protein bL17 7 117 1.2E-47 T 11-11-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06955 48f3553e35d28bb180ab637423edf647 131 Gene3D G3DSA:3.90.1030.10 1 117 2.5E-51 T 11-11-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06955 48f3553e35d28bb180ab637423edf647 131 SUPERFAMILY SSF64263 1 119 6.93E-52 T 11-11-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS11390 33a0855639e8d672e68e8cae3b5b88f1 458 SUPERFAMILY SSF56281 1 225 1.36E-42 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS11390 33a0855639e8d672e68e8cae3b5b88f1 458 SMART SM00450 252 349 3.6E-7 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS11390 33a0855639e8d672e68e8cae3b5b88f1 458 SMART SM00450 358 453 3.1E-14 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS11390 33a0855639e8d672e68e8cae3b5b88f1 458 Gene3D G3DSA:3.60.15.10 11 239 5.2E-48 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS11390 33a0855639e8d672e68e8cae3b5b88f1 458 SMART SM00849 12 180 2.9E-21 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS11390 33a0855639e8d672e68e8cae3b5b88f1 458 Pfam PF00581 Rhodanese-like domain 367 450 2.5E-8 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS11390 33a0855639e8d672e68e8cae3b5b88f1 458 Pfam PF00581 Rhodanese-like domain 256 345 4.9E-7 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS11390 33a0855639e8d672e68e8cae3b5b88f1 458 Pfam PF00753 Metallo-beta-lactamase superfamily 12 180 2.1E-11 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS11390 33a0855639e8d672e68e8cae3b5b88f1 458 SUPERFAMILY SSF52821 335 456 9.82E-27 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS11390 33a0855639e8d672e68e8cae3b5b88f1 458 Gene3D G3DSA:3.40.250.10 249 342 9.1E-16 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS11390 33a0855639e8d672e68e8cae3b5b88f1 458 Gene3D G3DSA:3.40.250.10 343 457 1.8E-23 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS11390 33a0855639e8d672e68e8cae3b5b88f1 458 SUPERFAMILY SSF52821 246 350 1.57E-18 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS13980 4c45494b576354f31b39866f579ff0c9 455 SUPERFAMILY SSF54001 251 387 4.91E-21 T 11-11-2016 AUP74_RS13980 4c45494b576354f31b39866f579ff0c9 455 Pfam PF01841 Transglutaminase-like superfamily 272 376 2.7E-17 T 11-11-2016 IPR002931 Transglutaminase-like AUP74_RS13980 4c45494b576354f31b39866f579ff0c9 455 SMART SM00460 317 379 1.3E-12 T 11-11-2016 IPR002931 Transglutaminase-like AUP74_RS16670 9fbb417a3cfff67995f8318f036f37c4 403 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 164 192 - T 11-11-2016 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 AUP74_RS16670 9fbb417a3cfff67995f8318f036f37c4 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 164 192 4.4E-19 T 11-11-2016 IPR003004 GspF/PilC family AUP74_RS16670 9fbb417a3cfff67995f8318f036f37c4 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 65 77 4.4E-19 T 11-11-2016 IPR003004 GspF/PilC family AUP74_RS16670 9fbb417a3cfff67995f8318f036f37c4 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 368 382 4.4E-19 T 11-11-2016 IPR003004 GspF/PilC family AUP74_RS16670 9fbb417a3cfff67995f8318f036f37c4 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 384 403 4.4E-19 T 11-11-2016 IPR003004 GspF/PilC family AUP74_RS16670 9fbb417a3cfff67995f8318f036f37c4 403 Pfam PF00482 Type II secretion system (T2SS), protein F 69 192 5.5E-33 T 11-11-2016 IPR018076 Type II secretion system F domain AUP74_RS16670 9fbb417a3cfff67995f8318f036f37c4 403 Pfam PF00482 Type II secretion system (T2SS), protein F 273 395 9.6E-30 T 11-11-2016 IPR018076 Type II secretion system F domain AUP74_RS08555 c7e0ecf46b1fc3b92d8ed3ab34977f04 580 Pfam PF00501 AMP-binding enzyme 29 432 1.2E-92 T 11-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 AUP74_RS08555 c7e0ecf46b1fc3b92d8ed3ab34977f04 580 Gene3D G3DSA:3.40.50.980 181 362 5.5E-30 T 11-11-2016 AUP74_RS08555 c7e0ecf46b1fc3b92d8ed3ab34977f04 580 Gene3D G3DSA:3.40.50.980 36 180 4.3E-34 T 11-11-2016 AUP74_RS08555 c7e0ecf46b1fc3b92d8ed3ab34977f04 580 Gene3D G3DSA:2.30.38.10 363 423 3.4E-17 T 11-11-2016 AUP74_RS08555 c7e0ecf46b1fc3b92d8ed3ab34977f04 580 ProSitePatterns PS00455 Putative AMP-binding domain signature. 175 186 - T 11-11-2016 IPR020845 AMP-binding, conserved site AUP74_RS08555 c7e0ecf46b1fc3b92d8ed3ab34977f04 580 SUPERFAMILY SSF56801 17 545 4.32E-109 T 11-11-2016 AUP74_RS15325 ef1e765fea7db75d23f114007bb11fef 331 Gene3D G3DSA:3.40.50.720 1 138 3.0E-46 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS15325 ef1e765fea7db75d23f114007bb11fef 331 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 194 216 - T 11-11-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site AUP74_RS15325 ef1e765fea7db75d23f114007bb11fef 331 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 327 1.0E-31 T 11-11-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 AUP74_RS15325 ef1e765fea7db75d23f114007bb11fef 331 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 147 174 - T 11-11-2016 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 AUP74_RS15325 ef1e765fea7db75d23f114007bb11fef 331 SUPERFAMILY SSF51735 102 298 6.09E-54 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS15325 ef1e765fea7db75d23f114007bb11fef 331 Gene3D G3DSA:3.40.50.720 139 304 7.6E-43 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS15325 ef1e765fea7db75d23f114007bb11fef 331 SUPERFAMILY SSF52283 2 135 3.59E-38 T 11-11-2016 AUP74_RS15325 ef1e765fea7db75d23f114007bb11fef 331 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 297 5.9E-54 T 11-11-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 AUP74_RS15020 d487e5ca8f207af8c30ba3628aed549c 203 Gene3D G3DSA:3.40.30.10 1 86 1.2E-29 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS15020 d487e5ca8f207af8c30ba3628aed549c 203 Pfam PF13417 Glutathione S-transferase, N-terminal domain 4 81 2.3E-17 T 11-11-2016 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 AUP74_RS15020 d487e5ca8f207af8c30ba3628aed549c 203 Pfam PF00043 Glutathione S-transferase, C-terminal domain 134 199 3.5E-12 T 11-11-2016 IPR004046 Glutathione S-transferase, C-terminal AUP74_RS15020 d487e5ca8f207af8c30ba3628aed549c 203 SUPERFAMILY SSF52833 1 89 3.03E-24 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS15020 d487e5ca8f207af8c30ba3628aed549c 203 Gene3D G3DSA:1.20.1050.10 87 202 4.1E-24 T 11-11-2016 IPR010987 Glutathione S-transferase, C-terminal-like AUP74_RS15020 d487e5ca8f207af8c30ba3628aed549c 203 SUPERFAMILY SSF47616 78 202 1.39E-26 T 11-11-2016 IPR010987 Glutathione S-transferase, C-terminal-like AUP74_RS10215 93fa3c9b02a39d5e08b549ae78144890 53 Hamap MF_01361 UPF0391 membrane protein YtjA [ytjA]. 1 52 21.02 T 11-11-2016 IPR009760 Protein of unknown function DUF1328 GO:0005886 AUP74_RS10215 93fa3c9b02a39d5e08b549ae78144890 53 Pfam PF07043 Protein of unknown function (DUF1328) 6 44 4.3E-17 T 11-11-2016 IPR009760 Protein of unknown function DUF1328 GO:0005886 AUP74_RS10215 93fa3c9b02a39d5e08b549ae78144890 53 PIRSF PIRSF036466 1 53 2.8E-24 T 11-11-2016 IPR009760 Protein of unknown function DUF1328 GO:0005886 AUP74_RS14480 41f03317b38f4b9286b1a896ec630fe4 399 SUPERFAMILY SSF89796 1 396 1.07E-130 T 11-11-2016 IPR023606 CoA-transferase family III domain AUP74_RS14480 41f03317b38f4b9286b1a896ec630fe4 399 Gene3D G3DSA:3.40.50.10540 307 396 1.0E-113 T 11-11-2016 IPR023606 CoA-transferase family III domain AUP74_RS14480 41f03317b38f4b9286b1a896ec630fe4 399 Gene3D G3DSA:3.40.50.10540 2 219 1.0E-113 T 11-11-2016 IPR023606 CoA-transferase family III domain AUP74_RS14480 41f03317b38f4b9286b1a896ec630fe4 399 Pfam PF02515 CoA-transferase family III 5 374 1.7E-122 T 11-11-2016 IPR003673 CoA-transferase family III GO:0003824 AUP74_RS14480 41f03317b38f4b9286b1a896ec630fe4 399 Gene3D G3DSA:3.30.1540.10 227 306 1.6E-23 T 11-11-2016 AUP74_RS05815 b66538a842deec9d91619614356e8b61 436 Gene3D G3DSA:3.40.630.40 296 371 2.2E-56 T 11-11-2016 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 AUP74_RS05815 b66538a842deec9d91619614356e8b61 436 Gene3D G3DSA:3.40.630.40 148 245 2.2E-56 T 11-11-2016 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 AUP74_RS05815 b66538a842deec9d91619614356e8b61 436 SUPERFAMILY SSF53187 148 244 1.57E-52 T 11-11-2016 AUP74_RS05815 b66538a842deec9d91619614356e8b61 436 SUPERFAMILY SSF53187 295 371 1.57E-52 T 11-11-2016 AUP74_RS05815 b66538a842deec9d91619614356e8b61 436 SMART SM00257 391 434 5.7E-16 T 11-11-2016 IPR018392 LysM domain AUP74_RS05815 b66538a842deec9d91619614356e8b61 436 Gene3D G3DSA:3.10.350.10 390 435 5.4E-18 T 11-11-2016 IPR018392 LysM domain AUP74_RS05815 b66538a842deec9d91619614356e8b61 436 Pfam PF01476 LysM domain 392 434 2.4E-13 T 11-11-2016 IPR018392 LysM domain AUP74_RS05815 b66538a842deec9d91619614356e8b61 436 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 150 368 6.3E-46 T 11-11-2016 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 AUP74_RS05815 b66538a842deec9d91619614356e8b61 436 SUPERFAMILY SSF54106 391 434 2.22E-11 T 11-11-2016 IPR018392 LysM domain AUP74_RS05815 b66538a842deec9d91619614356e8b61 436 Pfam PF11741 AMIN domain 29 128 1.3E-17 T 11-11-2016 IPR021731 AMIN domain AUP74_RS05815 b66538a842deec9d91619614356e8b61 436 SMART SM00646 210 368 1.3E-61 T 11-11-2016 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 AUP74_RS03090 2e36549403e57a9de78dde9b86212383 225 SUPERFAMILY SSF46785 1 64 1.65E-20 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS03090 2e36549403e57a9de78dde9b86212383 225 SUPERFAMILY SSF64288 48 223 1.43E-41 T 11-11-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain AUP74_RS03090 2e36549403e57a9de78dde9b86212383 225 SMART SM00866 81 218 1.2E-34 T 11-11-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 AUP74_RS03090 2e36549403e57a9de78dde9b86212383 225 Pfam PF00392 Bacterial regulatory proteins, gntR family 1 60 2.9E-18 T 11-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AUP74_RS03090 2e36549403e57a9de78dde9b86212383 225 Gene3D G3DSA:3.40.1410.10 78 214 3.7E-47 T 11-11-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain AUP74_RS03090 2e36549403e57a9de78dde9b86212383 225 TIGRFAM TIGR02018 his_ut_repres: histidine utilization repressor 1 223 5.5E-85 T 11-11-2016 IPR010248 Histidine utilization repressor GO:0003677|GO:0006547|GO:0045892 AUP74_RS03090 2e36549403e57a9de78dde9b86212383 225 SMART SM00345 1 60 1.5E-20 T 11-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AUP74_RS03090 2e36549403e57a9de78dde9b86212383 225 Gene3D G3DSA:1.10.10.10 1 65 1.0E-24 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS03090 2e36549403e57a9de78dde9b86212383 225 Pfam PF07702 UTRA domain 81 218 1.3E-30 T 11-11-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 AUP74_RS03090 2e36549403e57a9de78dde9b86212383 225 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 50 1.1E-9 T 11-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AUP74_RS03090 2e36549403e57a9de78dde9b86212383 225 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 20 34 1.1E-9 T 11-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AUP74_RS08470 cd68bc16407a4de192eb79ce5cd5eec2 332 PIRSF PIRSF005963 9 332 2.0E-133 T 11-11-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 AUP74_RS08470 cd68bc16407a4de192eb79ce5cd5eec2 332 Hamap MF_00206 Lipoyl synthase [lipA]. 1 332 152.393 T 11-11-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 AUP74_RS08470 cd68bc16407a4de192eb79ce5cd5eec2 332 SUPERFAMILY SSF102114 61 327 2.35E-68 T 11-11-2016 AUP74_RS08470 cd68bc16407a4de192eb79ce5cd5eec2 332 Gene3D G3DSA:3.20.20.70 63 324 3.6E-70 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS08470 cd68bc16407a4de192eb79ce5cd5eec2 332 Pfam PF04055 Radical SAM superfamily 101 261 1.9E-15 T 11-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 AUP74_RS08470 cd68bc16407a4de192eb79ce5cd5eec2 332 SMART SM00729 95 304 2.9E-12 T 11-11-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 AUP74_RS08470 cd68bc16407a4de192eb79ce5cd5eec2 332 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 44 84 6.5E-9 T 11-11-2016 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 AUP74_RS08470 cd68bc16407a4de192eb79ce5cd5eec2 332 TIGRFAM TIGR00510 lipA: lipoyl synthase 42 327 6.4E-134 T 11-11-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 AUP74_RS05935 f69c2bb9e19c267b603e451c6f9213ef 254 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 6 78 2.4E-20 T 11-11-2016 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 AUP74_RS05935 f69c2bb9e19c267b603e451c6f9213ef 254 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 5 250 4.7E-83 T 11-11-2016 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 AUP74_RS05935 f69c2bb9e19c267b603e451c6f9213ef 254 SUPERFAMILY SSF55315 3 78 9.06E-19 T 11-11-2016 IPR029064 50S ribosomal protein L30e-like AUP74_RS05935 f69c2bb9e19c267b603e451c6f9213ef 254 Pfam PF00588 SpoU rRNA Methylase family 104 244 6.5E-41 T 11-11-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 AUP74_RS05935 f69c2bb9e19c267b603e451c6f9213ef 254 Gene3D G3DSA:3.30.1330.30 3 77 2.2E-24 T 11-11-2016 IPR029064 50S ribosomal protein L30e-like AUP74_RS05935 f69c2bb9e19c267b603e451c6f9213ef 254 Hamap MF_01887 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB [rlmB]. 4 251 43.366 T 11-11-2016 IPR024915 23S rRNA (guanosine-2-O-)-methyltransferase RlmB AUP74_RS05935 f69c2bb9e19c267b603e451c6f9213ef 254 Gene3D G3DSA:3.40.1280.10 97 251 6.1E-57 T 11-11-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AUP74_RS05935 f69c2bb9e19c267b603e451c6f9213ef 254 SMART SM00967 6 83 4.0E-21 T 11-11-2016 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 AUP74_RS05935 f69c2bb9e19c267b603e451c6f9213ef 254 SUPERFAMILY SSF75217 95 251 4.58E-49 T 11-11-2016 IPR029028 Alpha/beta knot methyltransferases AUP74_RS13920 28493808a6cde6173b093d09e1c0b1db 294 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 6 282 8.2E-16 T 11-11-2016 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 AUP74_RS13920 28493808a6cde6173b093d09e1c0b1db 294 SUPERFAMILY SSF53067 116 282 2.78E-32 T 11-11-2016 AUP74_RS13920 28493808a6cde6173b093d09e1c0b1db 294 SUPERFAMILY SSF53067 1 108 5.67E-12 T 11-11-2016 AUP74_RS13350 110b134fdffd0dda18ead1354fa52143 481 Gene3D G3DSA:1.20.1600.10 45 460 3.8E-87 T 11-11-2016 AUP74_RS13350 110b134fdffd0dda18ead1354fa52143 481 SUPERFAMILY SSF56954 5 460 6.15E-83 T 11-11-2016 AUP74_RS13350 110b134fdffd0dda18ead1354fa52143 481 Pfam PF02321 Outer membrane efflux protein 280 456 5.8E-16 T 11-11-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 AUP74_RS13350 110b134fdffd0dda18ead1354fa52143 481 Pfam PF02321 Outer membrane efflux protein 58 249 2.5E-27 T 11-11-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 AUP74_RS13350 110b134fdffd0dda18ead1354fa52143 481 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 13 459 7.0E-83 T 11-11-2016 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 AUP74_RS11610 31ee467093c92493c126ed228a430368 1214 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1044 1129 2.3E-19 T 11-11-2016 AUP74_RS11610 31ee467093c92493c126ed228a430368 1214 Gene3D G3DSA:3.40.1140.10 3 240 2.4E-22 T 11-11-2016 AUP74_RS11610 31ee467093c92493c126ed228a430368 1214 Gene3D G3DSA:3.40.1140.10 1073 1170 2.1E-5 T 11-11-2016 AUP74_RS11610 31ee467093c92493c126ed228a430368 1214 SUPERFAMILY SSF52540 1006 1139 1.66E-8 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11610 31ee467093c92493c126ed228a430368 1214 SUPERFAMILY SSF52540 17 50 1.66E-8 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11610 31ee467093c92493c126ed228a430368 1214 Pfam PF13555 P-loop containing region of AAA domain 3 58 5.1E-11 T 11-11-2016 AUP74_RS15835 5571ffc7866643358a1138eab29eba63 212 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 9 212 39.644 T 11-11-2016 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AUP74_RS15835 5571ffc7866643358a1138eab29eba63 212 SUPERFAMILY SSF50475 18 212 5.43E-67 T 11-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 AUP74_RS15835 5571ffc7866643358a1138eab29eba63 212 PIRSF PIRSF000190 1 212 6.5E-84 T 11-11-2016 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AUP74_RS15835 5571ffc7866643358a1138eab29eba63 212 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 36 118 2.6E-23 T 11-11-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AUP74_RS15835 5571ffc7866643358a1138eab29eba63 212 Gene3D G3DSA:2.30.110.10 15 212 4.4E-85 T 11-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 AUP74_RS15835 5571ffc7866643358a1138eab29eba63 212 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 1 212 5.2E-89 T 11-11-2016 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AUP74_RS15835 5571ffc7866643358a1138eab29eba63 212 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 181 194 - T 11-11-2016 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AUP74_RS15835 5571ffc7866643358a1138eab29eba63 212 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 171 212 1.3E-20 T 11-11-2016 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AUP74_RS01020 446989bf23cdb939474c3638afda86c8 818 ProSitePatterns PS00523 Sulfatases signature 1. 142 154 - T 11-11-2016 IPR024607 Sulfatase, conserved site AUP74_RS01020 446989bf23cdb939474c3638afda86c8 818 Gene3D G3DSA:3.30.1120.10 543 630 6.0E-19 T 11-11-2016 AUP74_RS01020 446989bf23cdb939474c3638afda86c8 818 Gene3D G3DSA:3.40.720.10 97 538 2.1E-112 T 11-11-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 AUP74_RS01020 446989bf23cdb939474c3638afda86c8 818 SUPERFAMILY SSF53649 98 622 5.96E-135 T 11-11-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 AUP74_RS01020 446989bf23cdb939474c3638afda86c8 818 Pfam PF00884 Sulfatase 98 512 2.0E-83 T 11-11-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 AUP74_RS04530 acfc09f3022fa53c12a606b3ec40c620 322 SUPERFAMILY SSF55681 9 292 1.36E-138 T 11-11-2016 AUP74_RS04530 acfc09f3022fa53c12a606b3ec40c620 322 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 8 293 61.246 T 11-11-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AUP74_RS04530 acfc09f3022fa53c12a606b3ec40c620 322 Gene3D G3DSA:1.20.58.180 217 298 1.0E-37 T 11-11-2016 AUP74_RS04530 acfc09f3022fa53c12a606b3ec40c620 322 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 163 178 3.0E-69 T 11-11-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AUP74_RS04530 acfc09f3022fa53c12a606b3ec40c620 322 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 62 77 3.0E-69 T 11-11-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AUP74_RS04530 acfc09f3022fa53c12a606b3ec40c620 322 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 253 269 3.0E-69 T 11-11-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AUP74_RS04530 acfc09f3022fa53c12a606b3ec40c620 322 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 114 138 3.0E-69 T 11-11-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AUP74_RS04530 acfc09f3022fa53c12a606b3ec40c620 322 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 140 160 3.0E-69 T 11-11-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AUP74_RS04530 acfc09f3022fa53c12a606b3ec40c620 322 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 83 103 3.0E-69 T 11-11-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AUP74_RS04530 acfc09f3022fa53c12a606b3ec40c620 322 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 9 299 1.3E-162 T 11-11-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AUP74_RS04530 acfc09f3022fa53c12a606b3ec40c620 322 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 10 291 4.3E-152 T 11-11-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AUP74_RS04530 acfc09f3022fa53c12a606b3ec40c620 322 Gene3D G3DSA:3.30.930.10 6 216 3.1E-106 T 11-11-2016 AUP74_RS03715 a7ceecd8400f4ad803587aebcc13fbd8 254 SUPERFAMILY SSF53474 30 233 2.01E-22 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS03715 a7ceecd8400f4ad803587aebcc13fbd8 254 Gene3D G3DSA:3.40.50.1820 33 140 3.2E-24 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS03715 a7ceecd8400f4ad803587aebcc13fbd8 254 Gene3D G3DSA:3.40.50.1820 180 241 3.2E-24 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS15705 c6f2d0c4328f0597d166836727ed7fa6 183 Pfam PF00258 Flavodoxin 6 161 8.9E-28 T 11-11-2016 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 AUP74_RS15705 c6f2d0c4328f0597d166836727ed7fa6 183 TIGRFAM TIGR01752 flav_long: flavodoxin 3 169 8.8E-68 T 11-11-2016 IPR010086 Flavodoxin, long chain GO:0010181 AUP74_RS15705 c6f2d0c4328f0597d166836727ed7fa6 183 Gene3D G3DSA:3.40.50.360 2 169 1.2E-59 T 11-11-2016 IPR029039 Flavoprotein-like domain AUP74_RS15705 c6f2d0c4328f0597d166836727ed7fa6 183 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 11-11-2016 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 AUP74_RS15705 c6f2d0c4328f0597d166836727ed7fa6 183 PIRSF PIRSF038996 1 173 1.2E-64 T 11-11-2016 IPR010086 Flavodoxin, long chain GO:0010181 AUP74_RS15705 c6f2d0c4328f0597d166836727ed7fa6 183 SUPERFAMILY SSF52218 3 170 2.25E-49 T 11-11-2016 IPR029039 Flavoprotein-like domain AUP74_RS13015 9874c4b6f3110ad5a418851eb69160ee 326 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 5 152 6.0E-36 T 11-11-2016 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 AUP74_RS13015 9874c4b6f3110ad5a418851eb69160ee 326 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 156 322 3.3E-36 T 11-11-2016 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 AUP74_RS13015 9874c4b6f3110ad5a418851eb69160ee 326 SUPERFAMILY SSF51735 2 155 3.56E-43 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS13015 9874c4b6f3110ad5a418851eb69160ee 326 Hamap MF_01517 Malate dehydrogenase [mdh]. 1 325 55.975 T 11-11-2016 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 AUP74_RS13015 9874c4b6f3110ad5a418851eb69160ee 326 Gene3D G3DSA:3.40.50.720 3 153 3.8E-56 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS13015 9874c4b6f3110ad5a418851eb69160ee 326 SUPERFAMILY SSF56327 156 325 5.25E-64 T 11-11-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 AUP74_RS13015 9874c4b6f3110ad5a418851eb69160ee 326 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 3 321 4.0E-152 T 11-11-2016 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 AUP74_RS13015 9874c4b6f3110ad5a418851eb69160ee 326 Gene3D G3DSA:3.90.110.10 155 325 1.1E-76 T 11-11-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 AUP74_RS13015 9874c4b6f3110ad5a418851eb69160ee 326 ProSitePatterns PS00068 Malate dehydrogenase active site signature. 155 167 - T 11-11-2016 IPR001252 Malate dehydrogenase, active site GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|Reactome: R-HSA-70263 AUP74_RS13015 9874c4b6f3110ad5a418851eb69160ee 326 PIRSF PIRSF000102 1 324 7.4E-65 T 11-11-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AUP74_RS14105 3ee6f1ccf115037db85308635380e7c6 249 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 60 74 - T 11-11-2016 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS14105 3ee6f1ccf115037db85308635380e7c6 249 Pfam PF00849 RNA pseudouridylate synthase 20 181 9.8E-33 T 11-11-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS14105 3ee6f1ccf115037db85308635380e7c6 249 SUPERFAMILY SSF55120 13 248 1.39E-57 T 11-11-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS09045 3fa2928cc2180ed76d44a57f504ffe57 496 Pfam PF03553 Na+/H+ antiporter family 170 474 1.3E-54 T 11-11-2016 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 AUP74_RS09045 3fa2928cc2180ed76d44a57f504ffe57 496 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 11 473 7.5E-135 T 11-11-2016 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 AUP74_RS12595 8ba8e690d03d981feb7b3c1b28ab6ebd 367 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 4 360 2.7E-141 T 11-11-2016 IPR002780 Hydrogenase formation HypD protein GO:0046872 AUP74_RS12595 8ba8e690d03d981feb7b3c1b28ab6ebd 367 PIRSF PIRSF005622 1 364 4.6E-149 T 11-11-2016 IPR002780 Hydrogenase formation HypD protein GO:0046872 AUP74_RS12595 8ba8e690d03d981feb7b3c1b28ab6ebd 367 Pfam PF01924 Hydrogenase formation hypA family 13 358 1.1E-147 T 11-11-2016 IPR002780 Hydrogenase formation HypD protein GO:0046872 AUP74_RS13520 73eee2481bd55bd2cd3c4dc181d03b64 685 Pfam PF00289 Biotin carboxylase, N-terminal domain 16 122 1.2E-40 T 11-11-2016 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AUP74_RS13520 73eee2481bd55bd2cd3c4dc181d03b64 685 Gene3D G3DSA:3.30.1490.20 141 212 2.0E-26 T 11-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 AUP74_RS13520 73eee2481bd55bd2cd3c4dc181d03b64 685 SUPERFAMILY SSF52440 15 125 1.58E-43 T 11-11-2016 IPR016185 Pre-ATP-grasp domain AUP74_RS13520 73eee2481bd55bd2cd3c4dc181d03b64 685 Gene3D G3DSA:3.40.50.20 17 140 7.0E-46 T 11-11-2016 IPR016185 Pre-ATP-grasp domain AUP74_RS13520 73eee2481bd55bd2cd3c4dc181d03b64 685 SUPERFAMILY SSF51230 596 670 7.85E-19 T 11-11-2016 IPR011053 Single hybrid motif AUP74_RS13520 73eee2481bd55bd2cd3c4dc181d03b64 685 Gene3D G3DSA:2.40.50.100 599 670 5.4E-20 T 11-11-2016 AUP74_RS13520 73eee2481bd55bd2cd3c4dc181d03b64 685 Gene3D G3DSA:3.30.470.20 216 458 2.1E-92 T 11-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 AUP74_RS13520 73eee2481bd55bd2cd3c4dc181d03b64 685 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 11-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AUP74_RS13520 73eee2481bd55bd2cd3c4dc181d03b64 685 Pfam PF00364 Biotin-requiring enzyme 604 669 2.2E-12 T 11-11-2016 IPR000089 Biotin/lipoyl attachment AUP74_RS13520 73eee2481bd55bd2cd3c4dc181d03b64 685 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 11-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AUP74_RS13520 73eee2481bd55bd2cd3c4dc181d03b64 685 Pfam PF02785 Biotin carboxylase C-terminal domain 351 458 8.0E-31 T 11-11-2016 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AUP74_RS13520 73eee2481bd55bd2cd3c4dc181d03b64 685 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 5.7E-69 T 11-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AUP74_RS13520 73eee2481bd55bd2cd3c4dc181d03b64 685 SUPERFAMILY SSF51246 346 458 9.94E-37 T 11-11-2016 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AUP74_RS13520 73eee2481bd55bd2cd3c4dc181d03b64 685 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 626 643 - T 11-11-2016 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AUP74_RS13520 73eee2481bd55bd2cd3c4dc181d03b64 685 SUPERFAMILY SSF56059 95 359 1.54E-61 T 11-11-2016 AUP74_RS13520 73eee2481bd55bd2cd3c4dc181d03b64 685 SMART SM00878 351 457 1.5E-43 T 11-11-2016 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AUP74_RS15645 e22a557025df65044d3e9de755ad7173 245 Hamap MF_01220_B Uridylate kinase [pyrH]. 7 240 42.699 T 11-11-2016 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 AUP74_RS15645 e22a557025df65044d3e9de755ad7173 245 SUPERFAMILY SSF53633 8 239 1.03E-66 T 11-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase AUP74_RS15645 e22a557025df65044d3e9de755ad7173 245 Pfam PF00696 Amino acid kinase family 10 218 1.3E-25 T 11-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase AUP74_RS15645 e22a557025df65044d3e9de755ad7173 245 PIRSF PIRSF005650 4 245 1.5E-87 T 11-11-2016 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 AUP74_RS15645 e22a557025df65044d3e9de755ad7173 245 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 9 240 1.4E-95 T 11-11-2016 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 AUP74_RS15645 e22a557025df65044d3e9de755ad7173 245 Gene3D G3DSA:3.40.1160.10 5 240 5.1E-79 T 11-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase AUP74_RS15390 e4f111588fb19ec6dab1f5a152810358 464 Pfam PF13180 PDZ domain 391 454 3.1E-7 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS15390 e4f111588fb19ec6dab1f5a152810358 464 Pfam PF13180 PDZ domain 259 350 5.0E-16 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS15390 e4f111588fb19ec6dab1f5a152810358 464 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 27 458 1.3E-141 T 11-11-2016 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 AUP74_RS15390 e4f111588fb19ec6dab1f5a152810358 464 Gene3D G3DSA:2.40.10.10 19 148 1.1E-36 T 11-11-2016 AUP74_RS15390 e4f111588fb19ec6dab1f5a152810358 464 SMART SM00228 373 453 0.0077 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS15390 e4f111588fb19ec6dab1f5a152810358 464 SMART SM00228 259 341 1.1E-8 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS15390 e4f111588fb19ec6dab1f5a152810358 464 Pfam PF13365 Trypsin-like peptidase domain 84 220 3.0E-36 T 11-11-2016 AUP74_RS15390 e4f111588fb19ec6dab1f5a152810358 464 PRINTS PR00834 HtrA/DegQ protease family signature 154 178 4.2E-51 T 11-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AUP74_RS15390 e4f111588fb19ec6dab1f5a152810358 464 PRINTS PR00834 HtrA/DegQ protease family signature 213 230 4.2E-51 T 11-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AUP74_RS15390 e4f111588fb19ec6dab1f5a152810358 464 PRINTS PR00834 HtrA/DegQ protease family signature 299 311 4.2E-51 T 11-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AUP74_RS15390 e4f111588fb19ec6dab1f5a152810358 464 PRINTS PR00834 HtrA/DegQ protease family signature 114 134 4.2E-51 T 11-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AUP74_RS15390 e4f111588fb19ec6dab1f5a152810358 464 PRINTS PR00834 HtrA/DegQ protease family signature 93 105 4.2E-51 T 11-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AUP74_RS15390 e4f111588fb19ec6dab1f5a152810358 464 PRINTS PR00834 HtrA/DegQ protease family signature 191 208 4.2E-51 T 11-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AUP74_RS15390 e4f111588fb19ec6dab1f5a152810358 464 SUPERFAMILY SSF50156 217 342 3.68E-19 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS15390 e4f111588fb19ec6dab1f5a152810358 464 SUPERFAMILY SSF50156 373 463 2.5E-12 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS15390 e4f111588fb19ec6dab1f5a152810358 464 Gene3D G3DSA:2.30.42.10 373 463 1.9E-15 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS15390 e4f111588fb19ec6dab1f5a152810358 464 Gene3D G3DSA:2.30.42.10 261 357 9.6E-28 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS15390 e4f111588fb19ec6dab1f5a152810358 464 Gene3D G3DSA:2.40.10.10 149 260 1.7E-44 T 11-11-2016 AUP74_RS15390 e4f111588fb19ec6dab1f5a152810358 464 SUPERFAMILY SSF50494 24 251 1.73E-66 T 11-11-2016 IPR009003 Peptidase S1, PA clan AUP74_RS16270 7294d795e9dfa474913656680585f2d5 512 SUPERFAMILY SSF51445 17 355 1.42E-36 T 11-11-2016 IPR017853 Glycoside hydrolase superfamily AUP74_RS16270 7294d795e9dfa474913656680585f2d5 512 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 103 355 2.4E-6 T 11-11-2016 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 AUP74_RS16270 7294d795e9dfa474913656680585f2d5 512 Gene3D G3DSA:3.20.20.80 17 395 2.7E-67 T 11-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 AUP74_RS08460 d68525cf224ec1e66a214163cd4bcd9f 93 Pfam PF04359 Protein of unknown function (DUF493) 10 93 1.3E-25 T 11-11-2016 IPR007454 Uncharacterised protein family UPF0250 AUP74_RS08460 d68525cf224ec1e66a214163cd4bcd9f 93 Gene3D G3DSA:3.30.70.1460 7 93 7.1E-26 T 11-11-2016 IPR027471 YbeD-like domain AUP74_RS08460 d68525cf224ec1e66a214163cd4bcd9f 93 Hamap MF_00659 UPF0250 protein YbeD [ybeD]. 4 93 20.494 T 11-11-2016 IPR007454 Uncharacterised protein family UPF0250 AUP74_RS08460 d68525cf224ec1e66a214163cd4bcd9f 93 SUPERFAMILY SSF117991 7 93 2.09E-23 T 11-11-2016 IPR027471 YbeD-like domain AUP74_RS15945 babedfbdb454bcfe781bcecc8cca97cf 442 Gene3D G3DSA:3.30.565.10 300 442 2.1E-27 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS15945 babedfbdb454bcfe781bcecc8cca97cf 442 Gene3D G3DSA:1.10.287.130 229 284 4.0E-5 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS15945 babedfbdb454bcfe781bcecc8cca97cf 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 389 1.0E-6 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS15945 babedfbdb454bcfe781bcecc8cca97cf 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 424 1.0E-6 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS15945 babedfbdb454bcfe781bcecc8cca97cf 442 SUPERFAMILY SSF55874 302 442 4.19E-27 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS15945 babedfbdb454bcfe781bcecc8cca97cf 442 SUPERFAMILY SSF47384 220 287 3.73E-5 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS15945 babedfbdb454bcfe781bcecc8cca97cf 442 SMART SM00387 338 442 2.7E-16 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS15945 babedfbdb454bcfe781bcecc8cca97cf 442 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 338 440 1.2E-14 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS07310 84946e9ecfcd18105b0bdca1383445ed 647 Pfam PF03239 Iron permease FTR1 family 357 503 1.6E-23 T 11-11-2016 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0006827|GO:0016020|GO:0033573 AUP74_RS07310 84946e9ecfcd18105b0bdca1383445ed 647 SUPERFAMILY SSF46626 142 221 3.93E-12 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS07310 84946e9ecfcd18105b0bdca1383445ed 647 Gene3D G3DSA:1.10.760.10 143 222 9.7E-12 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS07310 84946e9ecfcd18105b0bdca1383445ed 647 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 141 220 4.7E-8 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS15585 0ec108234f091bf5f728894954e980dd 204 Hamap MF_00052_B Ribonuclease HII [rnhB]. 17 196 38.944 T 11-11-2016 IPR022898 Ribonuclease HII GO:0004523 AUP74_RS15585 0ec108234f091bf5f728894954e980dd 204 Gene3D G3DSA:3.30.420.10 17 157 9.0E-48 T 11-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 AUP74_RS15585 0ec108234f091bf5f728894954e980dd 204 Pfam PF01351 Ribonuclease HII 19 195 1.8E-42 T 11-11-2016 IPR024567 Ribonuclease HII/HIII domain AUP74_RS15585 0ec108234f091bf5f728894954e980dd 204 SUPERFAMILY SSF53098 14 199 7.44E-69 T 11-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 AUP74_RS01985 ef338cde6ce92d07d96679d1025996ae 811 SUPERFAMILY SSF51445 239 579 1.45E-68 T 11-11-2016 IPR017853 Glycoside hydrolase superfamily AUP74_RS01985 ef338cde6ce92d07d96679d1025996ae 811 SUPERFAMILY SSF51011 581 659 6.83E-18 T 11-11-2016 AUP74_RS01985 ef338cde6ce92d07d96679d1025996ae 811 Pfam PF13802 Galactose mutarotase-like 145 208 1.1E-13 T 11-11-2016 IPR025887 Glycoside hydrolase family 31, N-terminal domain AUP74_RS01985 ef338cde6ce92d07d96679d1025996ae 811 Pfam PF01055 Glycosyl hydrolases family 31 230 664 1.0E-115 T 11-11-2016 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 AUP74_RS01985 ef338cde6ce92d07d96679d1025996ae 811 SUPERFAMILY SSF74650 33 235 1.85E-35 T 11-11-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 AUP74_RS01985 ef338cde6ce92d07d96679d1025996ae 811 Pfam PF16338 Domain of unknown function (DUF4968) 36 125 6.3E-9 T 11-11-2016 IPR032513 Alpha-glucosidase, domain of unknown function DUF4968 AUP74_RS01985 ef338cde6ce92d07d96679d1025996ae 811 Pfam PF17137 Domain of unknown function (DUF5110) 681 755 6.6E-13 T 11-11-2016 IPR033403 Domain of unknown function DUF5110 AUP74_RS08915 81e7c124a541608384c508d5e6560c62 288 Gene3D G3DSA:3.90.550.10 1 264 1.6E-67 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases AUP74_RS08915 81e7c124a541608384c508d5e6560c62 288 SUPERFAMILY SSF53448 1 286 1.65E-91 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases AUP74_RS08915 81e7c124a541608384c508d5e6560c62 288 Pfam PF00483 Nucleotidyl transferase 2 238 1.1E-68 T 11-11-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 AUP74_RS08915 81e7c124a541608384c508d5e6560c62 288 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 286 4.1E-154 T 11-11-2016 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 AUP74_RS10340 68c56200c74979cfb1425f1e5146e0c3 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 5.1E-8 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS10340 68c56200c74979cfb1425f1e5146e0c3 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 5.1E-8 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS10340 68c56200c74979cfb1425f1e5146e0c3 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 5.1E-8 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS10340 68c56200c74979cfb1425f1e5146e0c3 296 SUPERFAMILY SSF46785 4 113 2.5E-21 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS10340 68c56200c74979cfb1425f1e5146e0c3 296 Gene3D G3DSA:3.40.190.10 91 177 6.9E-22 T 11-11-2016 AUP74_RS10340 68c56200c74979cfb1425f1e5146e0c3 296 SUPERFAMILY SSF53850 92 292 3.38E-44 T 11-11-2016 AUP74_RS10340 68c56200c74979cfb1425f1e5146e0c3 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 2.0E-19 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS10340 68c56200c74979cfb1425f1e5146e0c3 296 Pfam PF03466 LysR substrate binding domain 91 292 2.1E-43 T 11-11-2016 IPR005119 LysR, substrate-binding AUP74_RS10340 68c56200c74979cfb1425f1e5146e0c3 296 Gene3D G3DSA:3.40.190.10 178 264 2.8E-26 T 11-11-2016 AUP74_RS10340 68c56200c74979cfb1425f1e5146e0c3 296 Gene3D G3DSA:1.10.10.10 4 86 4.1E-27 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS12980 bb6f886965f32834cb934c4eca4a5c2d 444 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 243 258 - T 11-11-2016 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 AUP74_RS12980 bb6f886965f32834cb934c4eca4a5c2d 444 SMART SM01230 107 363 5.0E-110 T 11-11-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AUP74_RS12980 bb6f886965f32834cb934c4eca4a5c2d 444 SUPERFAMILY SSF54368 2 106 4.84E-22 T 11-11-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AUP74_RS12980 bb6f886965f32834cb934c4eca4a5c2d 444 Gene3D G3DSA:3.30.590.10 110 430 2.5E-95 T 11-11-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 AUP74_RS12980 bb6f886965f32834cb934c4eca4a5c2d 444 Gene3D G3DSA:3.10.20.70 2 107 5.3E-19 T 11-11-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AUP74_RS12980 bb6f886965f32834cb934c4eca4a5c2d 444 SUPERFAMILY SSF55931 107 441 9.42E-108 T 11-11-2016 AUP74_RS12980 bb6f886965f32834cb934c4eca4a5c2d 444 Pfam PF00120 Glutamine synthetase, catalytic domain 109 438 3.7E-105 T 11-11-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AUP74_RS12610 6918f241c8573776b32e8267acc5c1ba 92 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 67 4.5E-10 T 11-11-2016 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 AUP74_RS00960 f900332ad0bc87e6de2e17cb4e36f252 111 Gene3D G3DSA:3.10.20.280 2 98 2.5E-31 T 11-11-2016 IPR005346 RnfH protein AUP74_RS00960 f900332ad0bc87e6de2e17cb4e36f252 111 SUPERFAMILY SSF54285 6 88 7.59E-20 T 11-11-2016 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp AUP74_RS00960 f900332ad0bc87e6de2e17cb4e36f252 111 Pfam PF03658 RnfH family Ubiquitin 7 96 3.6E-30 T 11-11-2016 IPR005346 RnfH protein AUP74_RS00960 f900332ad0bc87e6de2e17cb4e36f252 111 Hamap MF_00460 Protein RnfH [rnfH]. 7 104 23.455 T 11-11-2016 IPR005346 RnfH protein AUP74_RS16395 8b596e8b709873e8782afc6685dd6d9c 204 Pfam PF04832 SOUL heme-binding protein 19 201 1.5E-49 T 11-11-2016 IPR006917 SOUL haem-binding protein AUP74_RS16395 8b596e8b709873e8782afc6685dd6d9c 204 Gene3D G3DSA:3.20.80.10 127 188 3.8E-4 T 11-11-2016 IPR011256 Regulatory factor, effector binding domain AUP74_RS16395 8b596e8b709873e8782afc6685dd6d9c 204 SUPERFAMILY SSF55136 11 202 1.5E-55 T 11-11-2016 IPR011256 Regulatory factor, effector binding domain AUP74_RS01435 11d1fa7e003770d644fe64936c4f7d74 853 Pfam PF13432 Tetratricopeptide repeat 627 681 3.7E-7 T 11-11-2016 AUP74_RS01435 11d1fa7e003770d644fe64936c4f7d74 853 Pfam PF00069 Protein kinase domain 14 273 6.1E-56 T 11-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AUP74_RS01435 11d1fa7e003770d644fe64936c4f7d74 853 SMART SM00220 14 281 2.3E-71 T 11-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AUP74_RS01435 11d1fa7e003770d644fe64936c4f7d74 853 SUPERFAMILY SSF48452 562 820 8.44E-17 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS01435 11d1fa7e003770d644fe64936c4f7d74 853 SUPERFAMILY SSF56112 9 276 1.19E-74 T 11-11-2016 IPR011009 Protein kinase-like domain AUP74_RS01435 11d1fa7e003770d644fe64936c4f7d74 853 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 20 44 - T 11-11-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 AUP74_RS01435 11d1fa7e003770d644fe64936c4f7d74 853 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 131 143 - T 11-11-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AUP74_RS01435 11d1fa7e003770d644fe64936c4f7d74 853 Gene3D G3DSA:1.25.40.10 563 821 6.9E-26 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS01435 11d1fa7e003770d644fe64936c4f7d74 853 Gene3D G3DSA:1.10.510.10 79 276 1.6E-49 T 11-11-2016 AUP74_RS01435 11d1fa7e003770d644fe64936c4f7d74 853 Gene3D G3DSA:3.30.200.20 5 78 2.4E-28 T 11-11-2016 AUP74_RS16915 4d2c0dd8911394bc73f608f7329739a4 77 PIRSF PIRSF003113 1 77 1.1E-18 T 11-11-2016 IPR002634 BolA protein AUP74_RS16915 4d2c0dd8911394bc73f608f7329739a4 77 Pfam PF01722 BolA-like protein 24 74 1.8E-15 T 11-11-2016 IPR002634 BolA protein AUP74_RS16915 4d2c0dd8911394bc73f608f7329739a4 77 SUPERFAMILY SSF82657 1 75 3.66E-23 T 11-11-2016 IPR002634 BolA protein AUP74_RS16915 4d2c0dd8911394bc73f608f7329739a4 77 Gene3D G3DSA:3.30.300.90 1 75 1.3E-23 T 11-11-2016 IPR002634 BolA protein AUP74_RS02160 3f1e50dbb310c18163a5f893789cc00c 222 Gene3D G3DSA:3.90.79.10 21 218 1.5E-49 T 11-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 AUP74_RS02160 3f1e50dbb310c18163a5f893789cc00c 222 SUPERFAMILY SSF55811 19 218 1.23E-45 T 11-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 AUP74_RS02160 3f1e50dbb310c18163a5f893789cc00c 222 ProSitePatterns PS00893 Nudix box signature. 106 127 - T 11-11-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AUP74_RS02160 3f1e50dbb310c18163a5f893789cc00c 222 TIGRFAM TIGR00052 TIGR00052: nudix-type nucleoside diphosphatase, YffH/AdpP family 25 212 4.7E-45 T 11-11-2016 IPR004385 Nucleoside diphosphate pyrophosphatase GO:0016818|GO:0046872 Reactome: R-HSA-480985 AUP74_RS02160 3f1e50dbb310c18163a5f893789cc00c 222 Pfam PF00293 NUDIX domain 65 190 7.4E-17 T 11-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 AUP74_RS04735 07836b93a28c52f418984ca18f66ecb1 156 Pfam PF09832 Uncharacterized protein conserved in bacteria (DUF2059) 81 137 1.0E-16 T 11-11-2016 IPR018637 Domain of unknown function DUF2059 AUP74_RS16510 c7c954cf60d69ecd837fbe462e61ecb2 256 SMART SM00947 96 256 2.7E-43 T 11-11-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 AUP74_RS16510 c7c954cf60d69ecd837fbe462e61ecb2 256 Gene3D G3DSA:3.40.1050.10 50 255 4.4E-51 T 11-11-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 AUP74_RS16510 c7c954cf60d69ecd837fbe462e61ecb2 256 Pfam PF00484 Carbonic anhydrase 104 252 1.2E-33 T 11-11-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 AUP74_RS16510 c7c954cf60d69ecd837fbe462e61ecb2 256 SUPERFAMILY SSF53056 49 255 2.62E-51 T 11-11-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 AUP74_RS07720 7eac9c12de68ca1850eb8c7ce933728b 191 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 119 130 - T 11-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AUP74_RS07720 7eac9c12de68ca1850eb8c7ce933728b 191 PIRSF PIRSF005784 7 190 1.6E-83 T 11-11-2016 IPR016463 Electron transport complex, RnfB/RsxB, Proteobacteria GO:0005886|GO:0022900|GO:0051536 AUP74_RS07720 7eac9c12de68ca1850eb8c7ce933728b 191 SUPERFAMILY SSF54862 42 171 1.05E-29 T 11-11-2016 AUP74_RS07720 7eac9c12de68ca1850eb8c7ce933728b 191 Pfam PF04060 Putative Fe-S cluster 48 79 1.6E-15 T 11-11-2016 IPR007202 4Fe-4S domain GO:0051536 AUP74_RS07720 7eac9c12de68ca1850eb8c7ce933728b 191 Pfam PF14697 4Fe-4S dicluster domain 112 166 2.4E-17 T 11-11-2016 AUP74_RS07720 7eac9c12de68ca1850eb8c7ce933728b 191 Gene3D G3DSA:3.30.70.20 125 172 7.2E-15 T 11-11-2016 AUP74_RS07720 7eac9c12de68ca1850eb8c7ce933728b 191 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 149 160 - T 11-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AUP74_RS07720 7eac9c12de68ca1850eb8c7ce933728b 191 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 12 184 1.7E-82 T 11-11-2016 IPR010207 Electron transport complex, RnfB/RsxB GO:0009055|GO:0051536 AUP74_RS07720 7eac9c12de68ca1850eb8c7ce933728b 191 Gene3D G3DSA:3.30.70.20 51 124 1.4E-5 T 11-11-2016 AUP74_RS07720 7eac9c12de68ca1850eb8c7ce933728b 191 Hamap MF_00463 Electron transport complex subunit RsxB [rsxB]. 8 189 41.004 T 11-11-2016 IPR016463 Electron transport complex, RnfB/RsxB, Proteobacteria GO:0005886|GO:0022900|GO:0051536 AUP74_RS11315 8f51aac59214f6ea239457852e854a71 98 SUPERFAMILY SSF46785 10 96 1.07E-24 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS11315 8f51aac59214f6ea239457852e854a71 98 SMART SM00418 15 93 6.0E-23 T 11-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AUP74_RS11315 8f51aac59214f6ea239457852e854a71 98 Gene3D G3DSA:1.10.10.10 3 97 2.4E-36 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS11315 8f51aac59214f6ea239457852e854a71 98 Pfam PF01022 Bacterial regulatory protein, arsR family 23 67 1.1E-12 T 11-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AUP74_RS11315 8f51aac59214f6ea239457852e854a71 98 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 17 32 4.0E-14 T 11-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AUP74_RS11315 8f51aac59214f6ea239457852e854a71 98 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 49 64 4.0E-14 T 11-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AUP74_RS11315 8f51aac59214f6ea239457852e854a71 98 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 36 47 4.0E-14 T 11-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AUP74_RS11315 8f51aac59214f6ea239457852e854a71 98 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 64 79 4.0E-14 T 11-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AUP74_RS06375 35b6e542c960fe0f652a147d69417a80 188 SUPERFAMILY SSF52172 65 187 1.25E-17 T 11-11-2016 IPR011006 CheY-like superfamily AUP74_RS06375 35b6e542c960fe0f652a147d69417a80 188 Gene3D G3DSA:3.40.50.2300 65 186 9.2E-17 T 11-11-2016 AUP74_RS06375 35b6e542c960fe0f652a147d69417a80 188 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 7 50 8.3E-9 T 11-11-2016 IPR010093 SinI-like, DNA-binding domain GO:0003677 AUP74_RS06375 35b6e542c960fe0f652a147d69417a80 188 Pfam PF00072 Response regulator receiver domain 78 183 5.6E-11 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS06375 35b6e542c960fe0f652a147d69417a80 188 SMART SM00448 70 182 2.4E-9 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS06375 35b6e542c960fe0f652a147d69417a80 188 Pfam PF12728 Helix-turn-helix domain 6 57 2.4E-9 T 11-11-2016 AUP74_RS06375 35b6e542c960fe0f652a147d69417a80 188 SUPERFAMILY SSF46955 6 57 4.58E-8 T 11-11-2016 IPR009061 Putative DNA-binding domain AUP74_RS11000 a275d12e95beb613fdf38e1f0e96db82 597 Gene3D G3DSA:1.10.540.10 39 159 6.9E-20 T 11-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 AUP74_RS11000 a275d12e95beb613fdf38e1f0e96db82 597 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 270 1.9E-16 T 11-11-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 AUP74_RS11000 a275d12e95beb613fdf38e1f0e96db82 597 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 281 449 9.7E-21 T 11-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AUP74_RS11000 a275d12e95beb613fdf38e1f0e96db82 597 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 39 156 6.7E-14 T 11-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 AUP74_RS11000 a275d12e95beb613fdf38e1f0e96db82 597 Gene3D G3DSA:1.20.140.10 268 462 1.8E-47 T 11-11-2016 AUP74_RS11000 a275d12e95beb613fdf38e1f0e96db82 597 Gene3D G3DSA:2.40.110.10 160 267 8.5E-27 T 11-11-2016 AUP74_RS11000 a275d12e95beb613fdf38e1f0e96db82 597 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 5 34 2.6E-6 T 11-11-2016 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria AUP74_RS11000 a275d12e95beb613fdf38e1f0e96db82 597 SUPERFAMILY SSF56645 38 278 9.69E-60 T 11-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 AUP74_RS11000 a275d12e95beb613fdf38e1f0e96db82 597 SUPERFAMILY SSF47203 286 473 7.89E-51 T 11-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AUP74_RS11000 a275d12e95beb613fdf38e1f0e96db82 597 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 465 591 9.7E-41 T 11-11-2016 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain AUP74_RS02655 845b3b40ee4138758072d509de51d5bd 146 Gene3D G3DSA:3.40.630.30 28 139 1.7E-25 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS02655 845b3b40ee4138758072d509de51d5bd 146 Pfam PF00583 Acetyltransferase (GNAT) family 53 132 8.0E-13 T 11-11-2016 IPR000182 GNAT domain GO:0008080 AUP74_RS02655 845b3b40ee4138758072d509de51d5bd 146 SUPERFAMILY SSF55729 30 137 4.12E-22 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS06225 d76a996d70abcec7ac38f828d5037cc0 287 SUPERFAMILY SSF50182 102 168 7.52E-16 T 11-11-2016 IPR010920 LSM domain AUP74_RS06225 d76a996d70abcec7ac38f828d5037cc0 287 SUPERFAMILY SSF82861 21 100 4.05E-12 T 11-11-2016 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 AUP74_RS06225 d76a996d70abcec7ac38f828d5037cc0 287 SUPERFAMILY SSF82689 171 273 6.67E-23 T 11-11-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 AUP74_RS06225 d76a996d70abcec7ac38f828d5037cc0 287 Gene3D G3DSA:2.30.30.60 117 167 4.5E-16 T 11-11-2016 AUP74_RS06225 d76a996d70abcec7ac38f828d5037cc0 287 Pfam PF00924 Mechanosensitive ion channel 60 263 8.1E-47 T 11-11-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 AUP74_RS06225 d76a996d70abcec7ac38f828d5037cc0 287 Gene3D G3DSA:3.30.70.100 171 261 2.1E-14 T 11-11-2016 AUP74_RS13655 e35655a0bbe535c3379eb1732c9f80a5 501 SUPERFAMILY SSF51905 298 407 6.85E-51 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS13655 e35655a0bbe535c3379eb1732c9f80a5 501 SUPERFAMILY SSF51905 6 230 6.85E-51 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS13655 e35655a0bbe535c3379eb1732c9f80a5 501 Pfam PF00743 Flavin-binding monooxygenase-like 81 344 3.3E-16 T 11-11-2016 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 AUP74_RS13655 e35655a0bbe535c3379eb1732c9f80a5 501 Pfam PF13450 NAD(P)-binding Rossmann-like domain 10 57 5.4E-8 T 11-11-2016 AUP74_RS13655 e35655a0bbe535c3379eb1732c9f80a5 501 Gene3D G3DSA:3.50.50.60 322 463 8.3E-9 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS13655 e35655a0bbe535c3379eb1732c9f80a5 501 Gene3D G3DSA:3.50.50.60 3 221 1.4E-52 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS00835 8f9aed6173fc2a3136f599cda465ed10 889 PIRSF PIRSF000156 1 889 0.0 T 11-11-2016 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 AUP74_RS00835 8f9aed6173fc2a3136f599cda465ed10 889 SUPERFAMILY SSF52518 53 462 2.07E-138 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS00835 8f9aed6173fc2a3136f599cda465ed10 889 SUPERFAMILY SSF52922 696 888 5.23E-50 T 11-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 AUP74_RS00835 8f9aed6173fc2a3136f599cda465ed10 889 SUPERFAMILY SSF52518 468 694 1.09E-95 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS00835 8f9aed6173fc2a3136f599cda465ed10 889 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 2 888 0.0 T 11-11-2016 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 AUP74_RS00835 8f9aed6173fc2a3136f599cda465ed10 889 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 79 288 7.7E-8 T 11-11-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AUP74_RS00835 8f9aed6173fc2a3136f599cda465ed10 889 Gene3D G3DSA:3.40.50.970 467 699 3.6E-117 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS00835 8f9aed6173fc2a3136f599cda465ed10 889 Gene3D G3DSA:3.40.50.970 52 465 3.1E-152 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS00835 8f9aed6173fc2a3136f599cda465ed10 889 Gene3D G3DSA:3.40.50.920 701 887 2.8E-63 T 11-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 AUP74_RS05855 2cbed777d4dabd05ef694035d985707c 440 Pfam PF00709 Adenylosuccinate synthetase 5 423 6.5E-174 T 11-11-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AUP74_RS05855 2cbed777d4dabd05ef694035d985707c 440 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 6 424 1.7E-184 T 11-11-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AUP74_RS05855 2cbed777d4dabd05ef694035d985707c 440 Gene3D G3DSA:1.10.300.10 104 196 8.9E-35 T 11-11-2016 AUP74_RS05855 2cbed777d4dabd05ef694035d985707c 440 Gene3D G3DSA:3.90.170.10 267 425 7.9E-66 T 11-11-2016 AUP74_RS05855 2cbed777d4dabd05ef694035d985707c 440 SMART SM00788 4 424 1.1E-293 T 11-11-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AUP74_RS05855 2cbed777d4dabd05ef694035d985707c 440 Gene3D G3DSA:3.40.440.10 3 94 5.4E-71 T 11-11-2016 AUP74_RS05855 2cbed777d4dabd05ef694035d985707c 440 Gene3D G3DSA:3.40.440.10 197 266 5.4E-71 T 11-11-2016 AUP74_RS05855 2cbed777d4dabd05ef694035d985707c 440 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 11 18 - T 11-11-2016 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AUP74_RS05855 2cbed777d4dabd05ef694035d985707c 440 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 133 144 - T 11-11-2016 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AUP74_RS05855 2cbed777d4dabd05ef694035d985707c 440 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 440 209.349 T 11-11-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AUP74_RS05855 2cbed777d4dabd05ef694035d985707c 440 SUPERFAMILY SSF52540 3 427 1.91E-174 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS02865 03243a07cf6216d1803ef182aa2f6eb7 410 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 121 295 7.3E-50 T 11-11-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 AUP74_RS02865 03243a07cf6216d1803ef182aa2f6eb7 410 Gene3D G3DSA:3.40.50.720 9 120 6.1E-38 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS02865 03243a07cf6216d1803ef182aa2f6eb7 410 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 14 327 5.1E-39 T 11-11-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 AUP74_RS02865 03243a07cf6216d1803ef182aa2f6eb7 410 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 230 246 - T 11-11-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site AUP74_RS02865 03243a07cf6216d1803ef182aa2f6eb7 410 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 155 182 - T 11-11-2016 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 AUP74_RS02865 03243a07cf6216d1803ef182aa2f6eb7 410 Gene3D G3DSA:3.40.50.720 121 298 4.7E-60 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS02865 03243a07cf6216d1803ef182aa2f6eb7 410 SUPERFAMILY SSF55021 337 409 4.23E-17 T 11-11-2016 AUP74_RS02865 03243a07cf6216d1803ef182aa2f6eb7 410 SUPERFAMILY SSF52283 9 135 1.25E-49 T 11-11-2016 AUP74_RS02865 03243a07cf6216d1803ef182aa2f6eb7 410 SUPERFAMILY SSF51735 109 296 2.51E-55 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS02865 03243a07cf6216d1803ef182aa2f6eb7 410 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 201 223 - T 11-11-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site AUP74_RS02865 03243a07cf6216d1803ef182aa2f6eb7 410 Gene3D G3DSA:3.30.70.260 325 409 3.2E-27 T 11-11-2016 AUP74_RS06050 769fa0204355eeb87561b1ce765f0997 319 Pfam PF00152 tRNA synthetases class II (D, K and N) 14 316 6.1E-33 T 11-11-2016 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS06050 769fa0204355eeb87561b1ce765f0997 319 SUPERFAMILY SSF55681 13 316 3.32E-64 T 11-11-2016 AUP74_RS06050 769fa0204355eeb87561b1ce765f0997 319 Gene3D G3DSA:3.30.930.10 15 315 8.7E-56 T 11-11-2016 AUP74_RS06050 769fa0204355eeb87561b1ce765f0997 319 TIGRFAM TIGR00462 genX: EF-P lysine aminoacylase GenX 17 314 3.6E-107 T 11-11-2016 IPR004525 Elongation factor P--(R)-beta-lysine ligase GO:0004824|GO:0005524|GO:0005737|GO:0006430 AUP74_RS11250 072e348f8a035ebed8d84930e8e6a2de 242 Pfam PF00929 Exonuclease 4 167 3.1E-40 T 11-11-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III AUP74_RS11250 072e348f8a035ebed8d84930e8e6a2de 242 TIGRFAM TIGR01406 dnaQ_proteo: DNA polymerase III, epsilon subunit 2 242 1.1E-89 T 11-11-2016 IPR006309 DNA polymerase 3, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS11250 072e348f8a035ebed8d84930e8e6a2de 242 SUPERFAMILY SSF53098 1 177 6.51E-57 T 11-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 AUP74_RS11250 072e348f8a035ebed8d84930e8e6a2de 242 Gene3D G3DSA:3.30.420.10 1 176 2.0E-64 T 11-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 AUP74_RS11250 072e348f8a035ebed8d84930e8e6a2de 242 SMART SM00479 2 176 1.7E-51 T 11-11-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III AUP74_RS11250 072e348f8a035ebed8d84930e8e6a2de 242 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 4 187 4.8E-63 T 11-11-2016 IPR006054 DNA polymerase III, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS00105 9bc0e9bd848593a3f65604b8a00a1ae6 483 SUPERFAMILY SSF55931 4 296 2.16E-119 T 11-11-2016 AUP74_RS00105 9bc0e9bd848593a3f65604b8a00a1ae6 483 Gene3D G3DSA:1.10.10.410 420 479 4.6E-6 T 11-11-2016 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal AUP74_RS00105 9bc0e9bd848593a3f65604b8a00a1ae6 483 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 479 1.8E-170 T 11-11-2016 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 AUP74_RS00105 9bc0e9bd848593a3f65604b8a00a1ae6 483 Pfam PF02637 GatB domain 328 479 1.5E-50 T 11-11-2016 IPR018027 Asn/Gln amidotransferase GO:0016884 AUP74_RS00105 9bc0e9bd848593a3f65604b8a00a1ae6 483 Pfam PF02934 GatB/GatE catalytic domain 5 289 2.8E-111 T 11-11-2016 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 AUP74_RS00105 9bc0e9bd848593a3f65604b8a00a1ae6 483 SMART SM00845 328 479 1.2E-77 T 11-11-2016 IPR018027 Asn/Gln amidotransferase GO:0016884 AUP74_RS00105 9bc0e9bd848593a3f65604b8a00a1ae6 483 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 480 38.093 T 11-11-2016 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 AUP74_RS00105 9bc0e9bd848593a3f65604b8a00a1ae6 483 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 144 158 - T 11-11-2016 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 AUP74_RS00105 9bc0e9bd848593a3f65604b8a00a1ae6 483 SUPERFAMILY SSF89095 297 402 4.92E-35 T 11-11-2016 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 AUP74_RS13575 c582e8c8f9cf2d1bdd77b0cde4fa58d8 238 SUPERFAMILY SSF52540 10 228 2.13E-70 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS13575 c582e8c8f9cf2d1bdd77b0cde4fa58d8 238 SMART SM00382 37 220 3.1E-14 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS13575 c582e8c8f9cf2d1bdd77b0cde4fa58d8 238 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AUP74_RS13575 c582e8c8f9cf2d1bdd77b0cde4fa58d8 238 Pfam PF00005 ABC transporter 28 171 4.6E-35 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AUP74_RS13575 c582e8c8f9cf2d1bdd77b0cde4fa58d8 238 Gene3D G3DSA:3.40.50.300 7 226 1.8E-67 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11280 47e17232bf791dbba438c9d66635c903 333 SUPERFAMILY SSF51735 120 294 1.1E-35 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS11280 47e17232bf791dbba438c9d66635c903 333 SUPERFAMILY SSF50129 6 147 2.95E-30 T 11-11-2016 IPR011032 GroES-like AUP74_RS11280 47e17232bf791dbba438c9d66635c903 333 Gene3D G3DSA:3.40.50.720 130 294 2.4E-64 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS11280 47e17232bf791dbba438c9d66635c903 333 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 7 331 3.0E-117 T 11-11-2016 IPR014188 Acrylyl-CoA reductase AcuI AUP74_RS11280 47e17232bf791dbba438c9d66635c903 333 SMART SM00829 16 329 0.0017 T 11-11-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AUP74_RS11280 47e17232bf791dbba438c9d66635c903 333 Pfam PF00107 Zinc-binding dehydrogenase 163 272 6.7E-14 T 11-11-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AUP74_RS02405 0862f937c05dfb1b2a436427b31b2383 362 Gene3D G3DSA:3.30.70.1400 54 137 1.1E-29 T 11-11-2016 AUP74_RS02405 0862f937c05dfb1b2a436427b31b2383 362 SUPERFAMILY SSF103025 4 277 2.51E-89 T 11-11-2016 AUP74_RS02405 0862f937c05dfb1b2a436427b31b2383 362 SUPERFAMILY SSF101790 270 359 7.68E-26 T 11-11-2016 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain AUP74_RS02405 0862f937c05dfb1b2a436427b31b2383 362 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 3 357 1.0E-136 T 11-11-2016 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 AUP74_RS02405 0862f937c05dfb1b2a436427b31b2383 362 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 262 352 1.9E-21 T 11-11-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 AUP74_RS02405 0862f937c05dfb1b2a436427b31b2383 362 PIRSF PIRSF006487 1 361 2.3E-81 T 11-11-2016 IPR028896 Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 AUP74_RS02405 0862f937c05dfb1b2a436427b31b2383 362 Gene3D G3DSA:2.40.30.110 279 359 6.6E-29 T 11-11-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 AUP74_RS02405 0862f937c05dfb1b2a436427b31b2383 362 Pfam PF01571 Aminomethyltransferase folate-binding domain 7 254 4.0E-83 T 11-11-2016 IPR006222 Glycine cleavage T-protein-like, N-terminal AUP74_RS02405 0862f937c05dfb1b2a436427b31b2383 362 Gene3D G3DSA:3.30.1360.120 4 53 1.8E-50 T 11-11-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 AUP74_RS02405 0862f937c05dfb1b2a436427b31b2383 362 Gene3D G3DSA:3.30.1360.120 144 231 1.8E-50 T 11-11-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 AUP74_RS02405 0862f937c05dfb1b2a436427b31b2383 362 Hamap MF_00259 Aminomethyltransferase [gcvT]. 1 357 44.322 T 11-11-2016 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 AUP74_RS16545 d8fa79ae01eaaf51ea4149d99d1523e2 388 Pfam PF00549 CoA-ligase 262 382 1.4E-24 T 11-11-2016 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AUP74_RS16545 d8fa79ae01eaaf51ea4149d99d1523e2 388 Gene3D G3DSA:3.30.470.20 96 239 1.2E-57 T 11-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 AUP74_RS16545 d8fa79ae01eaaf51ea4149d99d1523e2 388 SUPERFAMILY SSF52210 240 384 1.18E-53 T 11-11-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AUP74_RS16545 d8fa79ae01eaaf51ea4149d99d1523e2 388 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 282 - T 11-11-2016 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AUP74_RS16545 d8fa79ae01eaaf51ea4149d99d1523e2 388 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 1.9E-175 T 11-11-2016 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AUP74_RS16545 d8fa79ae01eaaf51ea4149d99d1523e2 388 Gene3D G3DSA:3.30.1490.20 21 95 2.7E-34 T 11-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 AUP74_RS16545 d8fa79ae01eaaf51ea4149d99d1523e2 388 Hamap MF_00558 Succinyl-CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 42.856 T 11-11-2016 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AUP74_RS16545 d8fa79ae01eaaf51ea4149d99d1523e2 388 SUPERFAMILY SSF56059 1 238 5.21E-82 T 11-11-2016 AUP74_RS16545 d8fa79ae01eaaf51ea4149d99d1523e2 388 Gene3D G3DSA:3.40.50.261 241 383 4.6E-66 T 11-11-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AUP74_RS16545 d8fa79ae01eaaf51ea4149d99d1523e2 388 Pfam PF08442 ATP-grasp domain 2 203 1.6E-81 T 11-11-2016 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AUP74_RS16545 d8fa79ae01eaaf51ea4149d99d1523e2 388 PIRSF PIRSF001554 1 388 1.7E-155 T 11-11-2016 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AUP74_RS11095 1b047e86176234af5a6d433c7aaa4fa1 149 Pfam PF04134 Protein of unknown function, DUF393 10 124 4.3E-30 T 11-11-2016 IPR007263 Protein of unknown function DUF393 AUP74_RS12685 66c2664c41d023fa22af32c7af4256fa 368 ProSitePatterns PS00195 Glutaredoxin active site. 27 43 - T 11-11-2016 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 AUP74_RS12685 66c2664c41d023fa22af32c7af4256fa 368 SUPERFAMILY SSF52833 20 111 2.21E-9 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS12685 66c2664c41d023fa22af32c7af4256fa 368 Gene3D G3DSA:3.40.30.10 26 97 4.7E-7 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS12685 66c2664c41d023fa22af32c7af4256fa 368 Pfam PF00462 Glutaredoxin 26 93 2.0E-7 T 11-11-2016 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 AUP74_RS14160 c7555925d4b049775a4535cd59cb159a 204 SUPERFAMILY SSF75217 17 189 1.18E-29 T 11-11-2016 IPR029028 Alpha/beta knot methyltransferases AUP74_RS14160 c7555925d4b049775a4535cd59cb159a 204 Pfam PF00588 SpoU rRNA Methylase family 25 179 2.0E-24 T 11-11-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 AUP74_RS14160 c7555925d4b049775a4535cd59cb159a 204 Gene3D G3DSA:3.40.1280.10 21 193 3.3E-37 T 11-11-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AUP74_RS06045 62a8da7d7bb34a0e542347c522df7d6c 266 Gene3D G3DSA:3.40.630.30 126 263 3.5E-14 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS06045 62a8da7d7bb34a0e542347c522df7d6c 266 Pfam PF13673 Acetyltransferase (GNAT) domain 158 238 1.7E-7 T 11-11-2016 IPR000182 GNAT domain GO:0008080 AUP74_RS06045 62a8da7d7bb34a0e542347c522df7d6c 266 SUPERFAMILY SSF55729 120 262 3.43E-15 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS03250 ec0422e16a47dfcdaafe47bf3fa82c3c 724 Gene3D G3DSA:2.40.170.20 149 724 1.3E-55 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS03250 ec0422e16a47dfcdaafe47bf3fa82c3c 724 Pfam PF00593 TonB dependent receptor 469 721 4.6E-18 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS03250 ec0422e16a47dfcdaafe47bf3fa82c3c 724 Gene3D G3DSA:2.170.130.10 25 148 2.3E-27 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS03250 ec0422e16a47dfcdaafe47bf3fa82c3c 724 Pfam PF07715 TonB-dependent Receptor Plug Domain 44 148 1.2E-18 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS03250 ec0422e16a47dfcdaafe47bf3fa82c3c 724 SUPERFAMILY SSF56935 30 723 1.13E-84 T 11-11-2016 AUP74_RS14770 1900b5da0d36e82c842762bf82d01451 103 Pfam PF12836 Helix-hairpin-helix motif 40 101 2.8E-22 T 11-11-2016 AUP74_RS14770 1900b5da0d36e82c842762bf82d01451 103 SUPERFAMILY SSF47781 38 101 7.34E-26 T 11-11-2016 IPR010994 RuvA domain 2-like AUP74_RS14770 1900b5da0d36e82c842762bf82d01451 103 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 41 102 2.8E-24 T 11-11-2016 IPR004509 Competence protein ComEA, helix-hairpin-helix domain AUP74_RS14770 1900b5da0d36e82c842762bf82d01451 103 SMART SM00278 81 100 40.0 T 11-11-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AUP74_RS14770 1900b5da0d36e82c842762bf82d01451 103 SMART SM00278 51 70 8.8 T 11-11-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AUP74_RS14770 1900b5da0d36e82c842762bf82d01451 103 Gene3D G3DSA:1.10.150.280 32 102 1.0E-16 T 11-11-2016 AUP74_RS13780 ea6c61eb831d99a26659fc587e86c8b8 325 SUPERFAMILY SSF103515 55 309 3.4E-12 T 11-11-2016 IPR005546 Autotransporter beta-domain AUP74_RS13780 ea6c61eb831d99a26659fc587e86c8b8 325 Pfam PF03797 Autotransporter beta-domain 57 295 1.1E-9 T 11-11-2016 IPR005546 Autotransporter beta-domain AUP74_RS13780 ea6c61eb831d99a26659fc587e86c8b8 325 Gene3D G3DSA:2.40.128.130 45 261 4.3E-7 T 11-11-2016 IPR005546 Autotransporter beta-domain AUP74_RS10520 1b9775dd04fdab168e11a4a2243f1194 96 SUPERFAMILY SSF54909 1 90 9.49E-16 T 11-11-2016 IPR011008 Dimeric alpha-beta barrel AUP74_RS10520 1b9775dd04fdab168e11a4a2243f1194 96 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 70 1.2E-5 T 11-11-2016 IPR007138 Antibiotic biosynthesis monooxygenase domain AUP74_RS10520 1b9775dd04fdab168e11a4a2243f1194 96 Gene3D G3DSA:3.30.70.900 1 86 3.9E-8 T 11-11-2016 AUP74_RS11060 ab3fef4f13ae5f3a60d34ffb854991fb 297 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 196 3.4E-17 T 11-11-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 AUP74_RS11060 ab3fef4f13ae5f3a60d34ffb854991fb 297 Gene3D G3DSA:3.40.50.720 12 269 4.0E-27 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS11060 ab3fef4f13ae5f3a60d34ffb854991fb 297 SUPERFAMILY SSF51735 3 278 4.02E-35 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS14180 8517fdd7e9521e766509331ba2d76bc6 185 Pfam PF14279 HNH endonuclease 90 144 2.9E-17 T 11-11-2016 IPR029471 HNH endonuclease 5 AUP74_RS14180 8517fdd7e9521e766509331ba2d76bc6 185 SMART SM00507 77 130 1.6E-10 T 11-11-2016 IPR003615 HNH nuclease AUP74_RS11130 629e55b53f02b6e73c4b6ea8c2346fd7 179 SUPERFAMILY SSF55961 32 178 3.97E-12 T 11-11-2016 AUP74_RS11130 629e55b53f02b6e73c4b6ea8c2346fd7 179 Gene3D G3DSA:3.30.530.20 36 177 1.2E-5 T 11-11-2016 IPR023393 START-like domain AUP74_RS02660 7497788d9071f8d03fe658f8fc563600 421 Gene3D G3DSA:2.40.160.60 27 421 2.6E-79 T 11-11-2016 AUP74_RS02660 7497788d9071f8d03fe658f8fc563600 421 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 33 389 2.5E-25 T 11-11-2016 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) AUP74_RS02660 7497788d9071f8d03fe658f8fc563600 421 SUPERFAMILY SSF56935 28 418 1.36E-48 T 11-11-2016 AUP74_RS06780 15e4a7e899c96b02af7921c5afee0a62 122 SUPERFAMILY SSF54736 51 122 1.52E-25 T 11-11-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like AUP74_RS06780 15e4a7e899c96b02af7921c5afee0a62 122 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 4 50 7.6E-16 T 11-11-2016 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06780 15e4a7e899c96b02af7921c5afee0a62 122 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 57 122 6.0E-21 T 11-11-2016 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06780 15e4a7e899c96b02af7921c5afee0a62 122 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 122 2.3E-45 T 11-11-2016 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06780 15e4a7e899c96b02af7921c5afee0a62 122 Gene3D G3DSA:1.20.5.710 2 51 6.3E-21 T 11-11-2016 AUP74_RS06780 15e4a7e899c96b02af7921c5afee0a62 122 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 122 24.432 T 11-11-2016 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06780 15e4a7e899c96b02af7921c5afee0a62 122 Gene3D G3DSA:3.30.1390.10 52 122 1.5E-34 T 11-11-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like AUP74_RS06780 15e4a7e899c96b02af7921c5afee0a62 122 SUPERFAMILY SSF48300 3 58 4.97E-14 T 11-11-2016 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06780 15e4a7e899c96b02af7921c5afee0a62 122 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 56 122 3.0E-32 T 11-11-2016 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS08655 b993e9a21be8af373431d0f11df90a1f 657 Gene3D G3DSA:3.40.50.200 100 460 8.3E-86 T 11-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AUP74_RS08655 b993e9a21be8af373431d0f11df90a1f 657 Pfam PF00082 Subtilase family 153 449 3.0E-47 T 11-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AUP74_RS08655 b993e9a21be8af373431d0f11df90a1f 657 SMART SM00089 472 550 9.9E-24 T 11-11-2016 IPR022409 PKD/Chitinase domain AUP74_RS08655 b993e9a21be8af373431d0f11df90a1f 657 SUPERFAMILY SSF52743 215 462 2.09E-75 T 11-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AUP74_RS08655 b993e9a21be8af373431d0f11df90a1f 657 SUPERFAMILY SSF52743 139 188 2.09E-75 T 11-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AUP74_RS08655 b993e9a21be8af373431d0f11df90a1f 657 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 400 410 - T 11-11-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site AUP74_RS08655 b993e9a21be8af373431d0f11df90a1f 657 Gene3D G3DSA:2.60.40.670 468 549 1.0E-23 T 11-11-2016 IPR000601 PKD domain AUP74_RS08655 b993e9a21be8af373431d0f11df90a1f 657 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 572 639 2.1E-13 T 11-11-2016 IPR007280 Peptidase, C-terminal, archaeal/bacterial AUP74_RS08655 b993e9a21be8af373431d0f11df90a1f 657 Pfam PF00801 PKD domain 482 538 5.0E-15 T 11-11-2016 IPR000601 PKD domain AUP74_RS08655 b993e9a21be8af373431d0f11df90a1f 657 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 222 232 - T 11-11-2016 IPR022398 Peptidase S8, subtilisin, His-active site AUP74_RS08655 b993e9a21be8af373431d0f11df90a1f 657 PRINTS PR00723 Subtilisin serine protease family (S8) signature 218 231 1.3E-14 T 11-11-2016 IPR015500 Peptidase S8, subtilisin-related AUP74_RS08655 b993e9a21be8af373431d0f11df90a1f 657 PRINTS PR00723 Subtilisin serine protease family (S8) signature 153 172 1.3E-14 T 11-11-2016 IPR015500 Peptidase S8, subtilisin-related AUP74_RS08655 b993e9a21be8af373431d0f11df90a1f 657 PRINTS PR00723 Subtilisin serine protease family (S8) signature 399 415 1.3E-14 T 11-11-2016 IPR015500 Peptidase S8, subtilisin-related AUP74_RS08655 b993e9a21be8af373431d0f11df90a1f 657 SUPERFAMILY SSF49299 457 549 5.36E-24 T 11-11-2016 IPR000601 PKD domain AUP74_RS13890 c0bb69bbf903a02801a7fa4cc87d15f5 467 SUPERFAMILY SSF51338 407 444 1.73E-26 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS13890 c0bb69bbf903a02801a7fa4cc87d15f5 467 SUPERFAMILY SSF51338 45 107 1.73E-26 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS13890 c0bb69bbf903a02801a7fa4cc87d15f5 467 Gene3D G3DSA:2.30.40.10 43 166 2.2E-34 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS13890 c0bb69bbf903a02801a7fa4cc87d15f5 467 Gene3D G3DSA:2.30.40.10 310 349 1.3E-23 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS13890 c0bb69bbf903a02801a7fa4cc87d15f5 467 Gene3D G3DSA:2.30.40.10 383 443 1.3E-23 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS13890 c0bb69bbf903a02801a7fa4cc87d15f5 467 Pfam PF01979 Amidohydrolase family 340 439 4.2E-13 T 11-11-2016 IPR006680 Amidohydrolase-related GO:0016787 AUP74_RS13890 c0bb69bbf903a02801a7fa4cc87d15f5 467 SUPERFAMILY SSF51556 106 408 7.14E-29 T 11-11-2016 IPR032466 Metal-dependent hydrolase AUP74_RS12385 931424b6c8fae6a1f223da8c2ffbafb7 405 SUPERFAMILY SSF103473 10 395 1.31E-31 T 11-11-2016 IPR020846 Major facilitator superfamily domain AUP74_RS12385 931424b6c8fae6a1f223da8c2ffbafb7 405 Gene3D G3DSA:1.20.1250.20 10 197 5.1E-14 T 11-11-2016 AUP74_RS12385 931424b6c8fae6a1f223da8c2ffbafb7 405 Gene3D G3DSA:1.20.1250.20 214 398 1.7E-13 T 11-11-2016 AUP74_RS12385 931424b6c8fae6a1f223da8c2ffbafb7 405 Pfam PF07690 Major Facilitator Superfamily 18 338 1.5E-18 T 11-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AUP74_RS10050 b3e2ca77c14b073e2e68d1459ba1cc9e 466 ProSitePatterns PS00216 Sugar transport proteins signature 1. 68 85 - T 11-11-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AUP74_RS10050 b3e2ca77c14b073e2e68d1459ba1cc9e 466 Gene3D G3DSA:1.20.1250.20 17 211 6.2E-22 T 11-11-2016 AUP74_RS10050 b3e2ca77c14b073e2e68d1459ba1cc9e 466 Gene3D G3DSA:1.20.1250.20 259 462 1.2E-23 T 11-11-2016 AUP74_RS10050 b3e2ca77c14b073e2e68d1459ba1cc9e 466 ProSitePatterns PS00217 Sugar transport proteins signature 2. 110 135 - T 11-11-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AUP74_RS10050 b3e2ca77c14b073e2e68d1459ba1cc9e 466 PRINTS PR00171 Sugar transporter signature 369 390 8.3E-24 T 11-11-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 AUP74_RS10050 b3e2ca77c14b073e2e68d1459ba1cc9e 466 PRINTS PR00171 Sugar transporter signature 392 404 8.3E-24 T 11-11-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 AUP74_RS10050 b3e2ca77c14b073e2e68d1459ba1cc9e 466 PRINTS PR00171 Sugar transporter signature 105 124 8.3E-24 T 11-11-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 AUP74_RS10050 b3e2ca77c14b073e2e68d1459ba1cc9e 466 PRINTS PR00171 Sugar transporter signature 272 282 8.3E-24 T 11-11-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 AUP74_RS10050 b3e2ca77c14b073e2e68d1459ba1cc9e 466 PRINTS PR00171 Sugar transporter signature 22 32 8.3E-24 T 11-11-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 AUP74_RS10050 b3e2ca77c14b073e2e68d1459ba1cc9e 466 SUPERFAMILY SSF103473 15 214 3.4E-65 T 11-11-2016 IPR020846 Major facilitator superfamily domain AUP74_RS10050 b3e2ca77c14b073e2e68d1459ba1cc9e 466 SUPERFAMILY SSF103473 242 464 3.4E-65 T 11-11-2016 IPR020846 Major facilitator superfamily domain AUP74_RS10050 b3e2ca77c14b073e2e68d1459ba1cc9e 466 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 9 464 5.9E-108 T 11-11-2016 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 AUP74_RS10050 b3e2ca77c14b073e2e68d1459ba1cc9e 466 ProSitePatterns PS00216 Sugar transport proteins signature 1. 316 333 - T 11-11-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AUP74_RS10050 b3e2ca77c14b073e2e68d1459ba1cc9e 466 Pfam PF00083 Sugar (and other) transporter 14 465 6.8E-111 T 11-11-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 AUP74_RS09055 7e42aaa2163121a4ce6205fae004330f 712 Pfam PF13307 Helicase C-terminal domain 550 706 8.7E-34 T 11-11-2016 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 AUP74_RS09055 7e42aaa2163121a4ce6205fae004330f 712 SUPERFAMILY SSF52540 57 109 2.94E-18 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS09055 7e42aaa2163121a4ce6205fae004330f 712 SUPERFAMILY SSF52540 474 687 2.94E-18 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS09055 7e42aaa2163121a4ce6205fae004330f 712 SUPERFAMILY SSF52540 214 287 2.94E-18 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS09055 7e42aaa2163121a4ce6205fae004330f 712 Gene3D G3DSA:3.40.50.300 534 688 9.7E-8 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS09055 7e42aaa2163121a4ce6205fae004330f 712 SMART SM00491 560 693 1.1E-30 T 11-11-2016 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 AUP74_RS09055 7e42aaa2163121a4ce6205fae004330f 712 Gene3D G3DSA:3.40.50.300 231 273 3.9E-14 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS09055 7e42aaa2163121a4ce6205fae004330f 712 Gene3D G3DSA:3.40.50.300 3 16 3.9E-14 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS09055 7e42aaa2163121a4ce6205fae004330f 712 Gene3D G3DSA:3.40.50.300 60 140 3.9E-14 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS15565 974328def1148fabaaa10784a6899c8e 79 Pfam PF00886 Ribosomal protein S16 8 68 6.3E-25 T 11-11-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS15565 974328def1148fabaaa10784a6899c8e 79 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 1 78 24.33 T 11-11-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS15565 974328def1148fabaaa10784a6899c8e 79 TIGRFAM TIGR00002 S16: ribosomal protein bS16 2 78 1.0E-28 T 11-11-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS15565 974328def1148fabaaa10784a6899c8e 79 SUPERFAMILY SSF54565 1 76 1.7E-29 T 11-11-2016 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS15565 974328def1148fabaaa10784a6899c8e 79 ProSitePatterns PS00732 Ribosomal protein S16 signature. 2 11 - T 11-11-2016 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS15565 974328def1148fabaaa10784a6899c8e 79 Gene3D G3DSA:3.30.1320.10 1 78 1.1E-33 T 11-11-2016 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS01510 f278fca09d849418e0f83980c41e0773 347 Gene3D G3DSA:3.40.50.300 94 250 2.9E-39 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS01510 f278fca09d849418e0f83980c41e0773 347 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 23 315 30.408 T 11-11-2016 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 AUP74_RS01510 f278fca09d849418e0f83980c41e0773 347 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 80 308 6.0E-45 T 11-11-2016 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 AUP74_RS01510 f278fca09d849418e0f83980c41e0773 347 Pfam PF03193 Protein of unknown function, DUF258 80 251 2.5E-44 T 11-11-2016 IPR010914 RsgA type GTPase domain GO:0003924|GO:0005525 AUP74_RS01510 f278fca09d849418e0f83980c41e0773 347 SUPERFAMILY SSF52540 95 314 5.7E-47 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS01510 f278fca09d849418e0f83980c41e0773 347 Gene3D G3DSA:1.10.40.50 255 318 1.3E-22 T 11-11-2016 AUP74_RS00075 05044ca2f59cd83cf72b59ed58b69ad2 207 PIRSF PIRSF006305 3 202 2.1E-46 T 11-11-2016 IPR003697 Maf-like protein GO:0005737 AUP74_RS00075 05044ca2f59cd83cf72b59ed58b69ad2 207 Hamap MF_00528 Septum formation protein Maf [maf]. 9 200 28.694 T 11-11-2016 IPR003697 Maf-like protein GO:0005737 AUP74_RS00075 05044ca2f59cd83cf72b59ed58b69ad2 207 Pfam PF02545 Maf-like protein 10 195 7.8E-49 T 11-11-2016 IPR003697 Maf-like protein GO:0005737 AUP74_RS00075 05044ca2f59cd83cf72b59ed58b69ad2 207 SUPERFAMILY SSF52972 8 195 1.83E-53 T 11-11-2016 IPR029001 Inosine triphosphate pyrophosphatase-like AUP74_RS00075 05044ca2f59cd83cf72b59ed58b69ad2 207 Gene3D G3DSA:3.90.950.10 8 198 6.1E-59 T 11-11-2016 IPR029001 Inosine triphosphate pyrophosphatase-like AUP74_RS00075 05044ca2f59cd83cf72b59ed58b69ad2 207 TIGRFAM TIGR00172 maf: septum formation protein Maf 8 193 2.4E-47 T 11-11-2016 IPR003697 Maf-like protein GO:0005737 AUP74_RS13375 8cfba36b2e931a993957649362295035 336 TIGRFAM TIGR03814 Gln_ase: glutaminase A 35 325 3.1E-104 T 11-11-2016 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 AUP74_RS13375 8cfba36b2e931a993957649362295035 336 SUPERFAMILY SSF56601 21 329 1.42E-101 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS13375 8cfba36b2e931a993957649362295035 336 Gene3D G3DSA:3.40.710.10 21 327 3.3E-109 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS13375 8cfba36b2e931a993957649362295035 336 Hamap MF_00313 Glutaminase [glsA]. 24 329 39.605 T 11-11-2016 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 AUP74_RS13375 8cfba36b2e931a993957649362295035 336 Pfam PF04960 Glutaminase 41 325 1.1E-101 T 11-11-2016 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 AUP74_RS00895 db7c0dcbba38134d154967d497027e2c 219 Gene3D G3DSA:3.20.20.70 30 108 1.0E-14 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS00895 db7c0dcbba38134d154967d497027e2c 219 Pfam PF13394 4Fe-4S single cluster domain 30 111 4.5E-9 T 11-11-2016 AUP74_RS00895 db7c0dcbba38134d154967d497027e2c 219 TIGRFAM TIGR04349 rSAM_QueE_gams: putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 9 218 7.0E-108 T 11-11-2016 IPR027621 Putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE AUP74_RS00895 db7c0dcbba38134d154967d497027e2c 219 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 9 216 35.522 T 11-11-2016 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 AUP74_RS00895 db7c0dcbba38134d154967d497027e2c 219 PIRSF PIRSF000370 7 218 3.3E-69 T 11-11-2016 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 AUP74_RS00895 db7c0dcbba38134d154967d497027e2c 219 SUPERFAMILY SSF102114 33 114 1.31E-15 T 11-11-2016 AUP74_RS00895 db7c0dcbba38134d154967d497027e2c 219 Pfam PF04055 Radical SAM superfamily 32 114 2.1E-15 T 11-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 AUP74_RS14640 cc0cf02ccfd0fcb7fbe652cb60a6ddb8 478 ProSitePatterns PS00450 Aconitase family signature 1. 344 360 - T 11-11-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 AUP74_RS14640 cc0cf02ccfd0fcb7fbe652cb60a6ddb8 478 PRINTS PR00415 Aconitase family signature 200 213 2.5E-39 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS14640 cc0cf02ccfd0fcb7fbe652cb60a6ddb8 478 PRINTS PR00415 Aconitase family signature 348 359 2.5E-39 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS14640 cc0cf02ccfd0fcb7fbe652cb60a6ddb8 478 PRINTS PR00415 Aconitase family signature 291 305 2.5E-39 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS14640 cc0cf02ccfd0fcb7fbe652cb60a6ddb8 478 PRINTS PR00415 Aconitase family signature 113 121 2.5E-39 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS14640 cc0cf02ccfd0fcb7fbe652cb60a6ddb8 478 PRINTS PR00415 Aconitase family signature 214 227 2.5E-39 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS14640 cc0cf02ccfd0fcb7fbe652cb60a6ddb8 478 PRINTS PR00415 Aconitase family signature 138 153 2.5E-39 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS14640 cc0cf02ccfd0fcb7fbe652cb60a6ddb8 478 PRINTS PR00415 Aconitase family signature 404 417 2.5E-39 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS14640 cc0cf02ccfd0fcb7fbe652cb60a6ddb8 478 PRINTS PR00415 Aconitase family signature 124 137 2.5E-39 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS14640 cc0cf02ccfd0fcb7fbe652cb60a6ddb8 478 SUPERFAMILY SSF53732 8 470 4.84E-150 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS14640 cc0cf02ccfd0fcb7fbe652cb60a6ddb8 478 Pfam PF00330 Aconitase family (aconitate hydratase) 11 462 4.7E-133 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS14640 cc0cf02ccfd0fcb7fbe652cb60a6ddb8 478 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 6 465 1.8E-169 T 11-11-2016 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 AUP74_RS14640 cc0cf02ccfd0fcb7fbe652cb60a6ddb8 478 Gene3D G3DSA:3.30.499.10 338 470 3.0E-52 T 11-11-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS14640 cc0cf02ccfd0fcb7fbe652cb60a6ddb8 478 Gene3D G3DSA:3.40.1060.10 160 293 1.1E-34 T 11-11-2016 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS14640 cc0cf02ccfd0fcb7fbe652cb60a6ddb8 478 Gene3D G3DSA:3.30.499.10 24 159 6.9E-26 T 11-11-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS05160 5d736bab53dabe7b129b0c2afd6f91cb 370 SUPERFAMILY SSF50331 236 361 5.35E-27 T 11-11-2016 IPR008995 Molybdate/tungstate binding, C-terminal AUP74_RS05160 5d736bab53dabe7b129b0c2afd6f91cb 370 SUPERFAMILY SSF52540 4 244 2.66E-84 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05160 5d736bab53dabe7b129b0c2afd6f91cb 370 Gene3D G3DSA:2.40.50.140 291 346 1.4E-13 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS05160 5d736bab53dabe7b129b0c2afd6f91cb 370 Gene3D G3DSA:2.40.50.100 239 290 3.4E-13 T 11-11-2016 AUP74_RS05160 5d736bab53dabe7b129b0c2afd6f91cb 370 Gene3D G3DSA:2.40.50.100 348 361 3.4E-13 T 11-11-2016 AUP74_RS05160 5d736bab53dabe7b129b0c2afd6f91cb 370 Pfam PF08402 TOBE domain 286 354 4.5E-11 T 11-11-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 AUP74_RS05160 5d736bab53dabe7b129b0c2afd6f91cb 370 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AUP74_RS05160 5d736bab53dabe7b129b0c2afd6f91cb 370 SMART SM00382 28 211 2.1E-14 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS05160 5d736bab53dabe7b129b0c2afd6f91cb 370 Gene3D G3DSA:3.40.50.300 4 234 1.9E-76 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05160 5d736bab53dabe7b129b0c2afd6f91cb 370 Pfam PF00005 ABC transporter 20 161 4.6E-32 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AUP74_RS01550 24913a2d0bae170810f9ad7a0996fa47 371 SUPERFAMILY SSF142695 204 367 1.7E-38 T 11-11-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 AUP74_RS01550 24913a2d0bae170810f9ad7a0996fa47 371 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 7 198 1.0E-83 T 11-11-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AUP74_RS01550 24913a2d0bae170810f9ad7a0996fa47 371 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 203 37.984 T 11-11-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AUP74_RS01550 24913a2d0bae170810f9ad7a0996fa47 371 PIRSF PIRSF001259 1 370 7.6E-112 T 11-11-2016 AUP74_RS01550 24913a2d0bae170810f9ad7a0996fa47 371 Gene3D G3DSA:3.90.870.10 1 210 7.6E-99 T 11-11-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain AUP74_RS01550 24913a2d0bae170810f9ad7a0996fa47 371 Pfam PF00925 GTP cyclohydrolase II 208 366 7.8E-28 T 11-11-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 AUP74_RS01550 24913a2d0bae170810f9ad7a0996fa47 371 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 4 199 1.3E-74 T 11-11-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AUP74_RS01550 24913a2d0bae170810f9ad7a0996fa47 371 SUPERFAMILY SSF55821 3 201 3.89E-86 T 11-11-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain AUP74_RS05850 43f63b5385a90462d68940b57bcecb28 394 Pfam PF13393 Histidyl-tRNA synthetase 12 322 2.6E-110 T 11-11-2016 AUP74_RS05850 43f63b5385a90462d68940b57bcecb28 394 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 15 326 1.6E-84 T 11-11-2016 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 AUP74_RS05850 43f63b5385a90462d68940b57bcecb28 394 SUPERFAMILY SSF55681 9 320 9.69E-52 T 11-11-2016 AUP74_RS05850 43f63b5385a90462d68940b57bcecb28 394 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 19 375 30.566 T 11-11-2016 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 AUP74_RS05850 43f63b5385a90462d68940b57bcecb28 394 PIRSF PIRSF001549 6 360 1.4E-43 T 11-11-2016 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 AUP74_RS05850 43f63b5385a90462d68940b57bcecb28 394 Gene3D G3DSA:3.30.930.10 21 322 1.1E-61 T 11-11-2016 AUP74_RS07050 5c1d7ae9df686dd4528e391fa0ecd717 88 TIGRFAM TIGR00029 S20: ribosomal protein bS20 2 86 1.4E-29 T 11-11-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS07050 5c1d7ae9df686dd4528e391fa0ecd717 88 Gene3D G3DSA:1.20.58.110 3 87 3.4E-33 T 11-11-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS07050 5c1d7ae9df686dd4528e391fa0ecd717 88 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 18.105 T 11-11-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS07050 5c1d7ae9df686dd4528e391fa0ecd717 88 Pfam PF01649 Ribosomal protein S20 2 84 3.3E-30 T 11-11-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS07050 5c1d7ae9df686dd4528e391fa0ecd717 88 SUPERFAMILY SSF46992 3 86 2.22E-33 T 11-11-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS07050 5c1d7ae9df686dd4528e391fa0ecd717 88 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 13 87 3.0E-28 T 11-11-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS15620 4f616fb6bd125f9589513aaa955a0a55 451 Pfam PF13180 PDZ domain 223 288 4.3E-7 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS15620 4f616fb6bd125f9589513aaa955a0a55 451 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 3 451 7.7E-118 T 11-11-2016 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 AUP74_RS15620 4f616fb6bd125f9589513aaa955a0a55 451 SUPERFAMILY SSF50156 194 292 1.58E-14 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS15620 4f616fb6bd125f9589513aaa955a0a55 451 SMART SM00228 113 186 2.6E-6 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS15620 4f616fb6bd125f9589513aaa955a0a55 451 SMART SM00228 211 280 0.24 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS15620 4f616fb6bd125f9589513aaa955a0a55 451 SUPERFAMILY SSF50156 88 188 2.76E-15 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS15620 4f616fb6bd125f9589513aaa955a0a55 451 Pfam PF02163 Peptidase family M50 10 438 3.9E-83 T 11-11-2016 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033 AUP74_RS15620 4f616fb6bd125f9589513aaa955a0a55 451 Gene3D G3DSA:2.30.42.10 200 290 8.4E-16 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS15620 4f616fb6bd125f9589513aaa955a0a55 451 Gene3D G3DSA:2.30.42.10 94 185 1.4E-18 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS13635 1268f6f486d6ca3f9e461c300b969e53 334 Gene3D G3DSA:3.40.50.1000 64 79 5.1E-17 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS13635 1268f6f486d6ca3f9e461c300b969e53 334 Gene3D G3DSA:3.40.50.1000 162 306 5.1E-17 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS13635 1268f6f486d6ca3f9e461c300b969e53 334 SUPERFAMILY SSF56784 64 315 2.71E-25 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS13635 1268f6f486d6ca3f9e461c300b969e53 334 Pfam PF12710 haloacid dehalogenase-like hydrolase 66 270 5.8E-22 T 11-11-2016 AUP74_RS03905 b1cdbcf536056fbbebf631e317e5b746 161 Pfam PF09523 Protein of unknown function (DUF2390) 15 117 2.5E-22 T 11-11-2016 IPR012659 Conserved hypothetical protein CHP02444 AUP74_RS03905 b1cdbcf536056fbbebf631e317e5b746 161 TIGRFAM TIGR02444 TIGR02444: TIGR02444 family protein 14 119 7.0E-18 T 11-11-2016 IPR012659 Conserved hypothetical protein CHP02444 AUP74_RS13925 bcecf7c60b1ea9ab9c6588895431745f 315 Pfam PF13580 SIS domain 52 171 4.7E-10 T 11-11-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 AUP74_RS13925 bcecf7c60b1ea9ab9c6588895431745f 315 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 8 301 42.449 T 11-11-2016 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 AUP74_RS13925 bcecf7c60b1ea9ab9c6588895431745f 315 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 12 301 3.4E-122 T 11-11-2016 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 AUP74_RS13925 bcecf7c60b1ea9ab9c6588895431745f 315 SUPERFAMILY SSF53697 12 254 1.53E-69 T 11-11-2016 AUP74_RS13925 bcecf7c60b1ea9ab9c6588895431745f 315 Gene3D G3DSA:3.40.50.10490 9 255 4.7E-86 T 11-11-2016 AUP74_RS13925 bcecf7c60b1ea9ab9c6588895431745f 315 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 191 208 - T 11-11-2016 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 AUP74_RS07170 187f4c16c7699222ffed4e3363273d85 542 Pfam PF02540 NAD synthase 267 514 3.8E-75 T 11-11-2016 IPR022310 NAD/GMP synthase AUP74_RS07170 187f4c16c7699222ffed4e3363273d85 542 Gene3D G3DSA:3.40.50.620 260 522 2.2E-76 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS07170 187f4c16c7699222ffed4e3363273d85 542 Pfam PF00795 Carbon-nitrogen hydrolase 9 241 3.6E-26 T 11-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AUP74_RS07170 187f4c16c7699222ffed4e3363273d85 542 ProSitePatterns PS00920 Nitrilases / cyanide hydratase signature 1. 37 52 - T 11-11-2016 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 AUP74_RS07170 187f4c16c7699222ffed4e3363273d85 542 SUPERFAMILY SSF56317 1 242 3.01E-58 T 11-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AUP74_RS07170 187f4c16c7699222ffed4e3363273d85 542 Gene3D G3DSA:3.60.110.10 2 242 3.8E-57 T 11-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AUP74_RS07170 187f4c16c7699222ffed4e3363273d85 542 TIGRFAM TIGR00552 nadE: NAD+ synthetase 274 514 3.9E-62 T 11-11-2016 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 AUP74_RS07170 187f4c16c7699222ffed4e3363273d85 542 SUPERFAMILY SSF52402 261 523 4.63E-79 T 11-11-2016 AUP74_RS00640 3fd20664bc453da354dab0a65dfa2d85 349 PIRSF PIRSF018266 6 347 2.0E-82 T 11-11-2016 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component AUP74_RS00640 3fd20664bc453da354dab0a65dfa2d85 349 Pfam PF16220 Domain of unknown function (DUF4880) 16 57 5.8E-12 T 11-11-2016 IPR032623 FecR, N-terminal AUP74_RS00640 3fd20664bc453da354dab0a65dfa2d85 349 Pfam PF04773 FecR protein 137 227 2.2E-22 T 11-11-2016 IPR006860 FecR protein AUP74_RS00640 3fd20664bc453da354dab0a65dfa2d85 349 Pfam PF16344 Domain of unknown function (DUF4974) 247 329 9.3E-10 T 11-11-2016 IPR032508 Protein FecR, C-terminal AUP74_RS06420 db511bf972cba7837aee49d48cd3593d 449 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 328 349 - T 11-11-2016 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-936440 AUP74_RS06420 db511bf972cba7837aee49d48cd3593d 449 Pfam PF13616 PPIC-type PPIASE domain 287 389 3.6E-24 T 11-11-2016 AUP74_RS06420 db511bf972cba7837aee49d48cd3593d 449 Pfam PF09312 SurA N-terminal domain 34 150 4.7E-39 T 11-11-2016 IPR015391 SurA N-terminal AUP74_RS06420 db511bf972cba7837aee49d48cd3593d 449 SUPERFAMILY SSF54534 291 392 1.7E-29 T 11-11-2016 AUP74_RS06420 db511bf972cba7837aee49d48cd3593d 449 Hamap MF_01183 Chaperone SurA [surA]. 13 435 33.548 T 11-11-2016 IPR023034 Peptidyl-prolyl isomerase SurA GO:0003755|GO:0006457|GO:0030288|GO:0042277|GO:0042710|GO:0043165|GO:0050821|GO:0051082|GO:0051085|GO:0060274 AUP74_RS06420 db511bf972cba7837aee49d48cd3593d 449 Gene3D G3DSA:3.10.50.40 290 411 4.7E-35 T 11-11-2016 AUP74_RS06420 db511bf972cba7837aee49d48cd3593d 449 Gene3D G3DSA:3.10.50.40 176 287 4.4E-27 T 11-11-2016 AUP74_RS06420 db511bf972cba7837aee49d48cd3593d 449 SUPERFAMILY SSF109998 34 210 4.51E-45 T 11-11-2016 IPR027304 Trigger factor/SurA domain AUP74_RS06420 db511bf972cba7837aee49d48cd3593d 449 Pfam PF00639 PPIC-type PPIASE domain 187 280 1.8E-18 T 11-11-2016 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 AUP74_RS06420 db511bf972cba7837aee49d48cd3593d 449 SUPERFAMILY SSF54534 182 283 3.99E-24 T 11-11-2016 AUP74_RS11100 7be385eaf6556eac46a2430e7a1a4cac 154 Gene3D G3DSA:3.10.50.40 2 80 6.3E-22 T 11-11-2016 AUP74_RS11100 7be385eaf6556eac46a2430e7a1a4cac 154 Gene3D G3DSA:3.10.50.40 127 142 6.3E-22 T 11-11-2016 AUP74_RS11100 7be385eaf6556eac46a2430e7a1a4cac 154 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 137 4.4E-14 T 11-11-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 AUP74_RS11100 7be385eaf6556eac46a2430e7a1a4cac 154 SUPERFAMILY SSF54534 2 141 8.84E-36 T 11-11-2016 AUP74_RS09200 434620c86a75d773b76b2b774d5f3e04 673 Pfam PF13899 Thioredoxin-like 553 639 9.3E-17 T 11-11-2016 AUP74_RS09200 434620c86a75d773b76b2b774d5f3e04 673 Pfam PF11412 Disulphide bond corrector protein DsbC 38 145 4.6E-16 T 11-11-2016 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain AUP74_RS09200 434620c86a75d773b76b2b774d5f3e04 673 SUPERFAMILY SSF52833 552 640 4.41E-13 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS09200 434620c86a75d773b76b2b774d5f3e04 673 Gene3D G3DSA:3.40.30.10 554 639 5.7E-14 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS11795 ba1bf9bff3fc94ab304adeed717496e8 732 SUPERFAMILY SSF53335 145 226 5.36E-35 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS11795 ba1bf9bff3fc94ab304adeed717496e8 732 SUPERFAMILY SSF53335 267 382 5.36E-35 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS11795 ba1bf9bff3fc94ab304adeed717496e8 732 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 204 215 - T 11-11-2016 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AUP74_RS11795 ba1bf9bff3fc94ab304adeed717496e8 732 Pfam PF02926 THUMP domain 49 158 6.6E-8 T 11-11-2016 IPR004114 THUMP domain GO:0003723 AUP74_RS11795 ba1bf9bff3fc94ab304adeed717496e8 732 Pfam PF01170 Putative RNA methylase family UPF0020 167 381 2.4E-43 T 11-11-2016 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AUP74_RS11795 ba1bf9bff3fc94ab304adeed717496e8 732 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 316 322 - T 11-11-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 AUP74_RS11795 ba1bf9bff3fc94ab304adeed717496e8 732 SMART SM00981 61 159 7.5E-13 T 11-11-2016 IPR004114 THUMP domain GO:0003723 AUP74_RS11795 ba1bf9bff3fc94ab304adeed717496e8 732 Gene3D G3DSA:3.40.50.150 154 223 7.3E-22 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS11795 ba1bf9bff3fc94ab304adeed717496e8 732 Gene3D G3DSA:3.40.50.150 264 366 7.3E-22 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS11795 ba1bf9bff3fc94ab304adeed717496e8 732 SUPERFAMILY SSF53335 410 726 3.16E-54 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS11795 ba1bf9bff3fc94ab304adeed717496e8 732 Hamap MF_01858 Ribosomal RNA large subunit methyltransferase K/L [rlmL]. 9 731 30.994 T 11-11-2016 IPR017244 Ribosomal RNA large subunit methyltransferase K/L GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AUP74_RS11795 ba1bf9bff3fc94ab304adeed717496e8 732 PIRSF PIRSF037618 4 732 8.2E-284 T 11-11-2016 IPR017244 Ribosomal RNA large subunit methyltransferase K/L GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 AUP74_RS11795 ba1bf9bff3fc94ab304adeed717496e8 732 Gene3D G3DSA:3.40.50.150 457 730 2.0E-62 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS11795 ba1bf9bff3fc94ab304adeed717496e8 732 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 527 711 2.2E-24 T 11-11-2016 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 AUP74_RS16245 0e7b031ba700fe46c73ba5f46d39741f 160 Pfam PF14317 YcxB-like protein 96 146 1.7E-7 T 11-11-2016 IPR025588 YcxB-like protein AUP74_RS15840 bef3e880e7d57fe2dea05dbb615aa1c0 534 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 389 531 1.6E-31 T 11-11-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AUP74_RS15840 bef3e880e7d57fe2dea05dbb615aa1c0 534 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 196 328 4.4E-28 T 11-11-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 AUP74_RS15840 bef3e880e7d57fe2dea05dbb615aa1c0 534 SUPERFAMILY SSF52518 6 175 2.46E-51 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS15840 bef3e880e7d57fe2dea05dbb615aa1c0 534 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 6 173 1.9E-53 T 11-11-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 AUP74_RS15840 bef3e880e7d57fe2dea05dbb615aa1c0 534 Gene3D G3DSA:3.40.50.1220 189 380 3.9E-38 T 11-11-2016 IPR029035 DHS-like NAD/FAD-binding domain AUP74_RS15840 bef3e880e7d57fe2dea05dbb615aa1c0 534 SUPERFAMILY SSF52518 369 532 2.95E-45 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS15840 bef3e880e7d57fe2dea05dbb615aa1c0 534 Gene3D G3DSA:3.40.50.970 6 175 1.9E-56 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS15840 bef3e880e7d57fe2dea05dbb615aa1c0 534 SUPERFAMILY SSF52467 159 349 5.73E-34 T 11-11-2016 IPR029035 DHS-like NAD/FAD-binding domain AUP74_RS15840 bef3e880e7d57fe2dea05dbb615aa1c0 534 Gene3D G3DSA:3.40.50.970 381 532 9.2E-47 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS11705 09dd59c3cdfb9ba1c258ed4d8179e698 291 Pfam PF01513 ATP-NAD kinase 50 271 8.7E-64 T 11-11-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 AUP74_RS11705 09dd59c3cdfb9ba1c258ed4d8179e698 291 SUPERFAMILY SSF111331 6 289 1.44E-86 T 11-11-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain AUP74_RS11705 09dd59c3cdfb9ba1c258ed4d8179e698 291 Gene3D G3DSA:2.60.200.30 150 261 1.7E-41 T 11-11-2016 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 AUP74_RS11705 09dd59c3cdfb9ba1c258ed4d8179e698 291 Gene3D G3DSA:3.40.50.10330 3 149 3.4E-38 T 11-11-2016 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 AUP74_RS11705 09dd59c3cdfb9ba1c258ed4d8179e698 291 Hamap MF_00361 NAD kinase [nadK]. 5 287 33.455 T 11-11-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 AUP74_RS11230 724a4eea5f37cf35657edb1e280648e9 517 Gene3D G3DSA:1.10.530.10 99 261 3.6E-46 T 11-11-2016 AUP74_RS11230 724a4eea5f37cf35657edb1e280648e9 517 SMART SM00257 335 378 2.9E-14 T 11-11-2016 IPR018392 LysM domain AUP74_RS11230 724a4eea5f37cf35657edb1e280648e9 517 SMART SM00257 408 452 2.1E-10 T 11-11-2016 IPR018392 LysM domain AUP74_RS11230 724a4eea5f37cf35657edb1e280648e9 517 SMART SM00257 466 510 6.9E-13 T 11-11-2016 IPR018392 LysM domain AUP74_RS11230 724a4eea5f37cf35657edb1e280648e9 517 SUPERFAMILY SSF54106 407 450 6.41E-10 T 11-11-2016 IPR018392 LysM domain AUP74_RS11230 724a4eea5f37cf35657edb1e280648e9 517 SUPERFAMILY SSF54106 334 378 1.19E-10 T 11-11-2016 IPR018392 LysM domain AUP74_RS11230 724a4eea5f37cf35657edb1e280648e9 517 Gene3D G3DSA:3.10.350.10 407 450 4.3E-15 T 11-11-2016 IPR018392 LysM domain AUP74_RS11230 724a4eea5f37cf35657edb1e280648e9 517 Gene3D G3DSA:3.10.350.10 466 510 7.6E-16 T 11-11-2016 IPR018392 LysM domain AUP74_RS11230 724a4eea5f37cf35657edb1e280648e9 517 Gene3D G3DSA:3.10.350.10 333 379 7.6E-17 T 11-11-2016 IPR018392 LysM domain AUP74_RS11230 724a4eea5f37cf35657edb1e280648e9 517 Pfam PF01464 Transglycosylase SLT domain 117 214 7.6E-23 T 11-11-2016 IPR008258 Transglycosylase SLT domain 1 AUP74_RS11230 724a4eea5f37cf35657edb1e280648e9 517 SUPERFAMILY SSF53955 103 251 7.12E-41 T 11-11-2016 IPR023346 Lysozyme-like domain AUP74_RS11230 724a4eea5f37cf35657edb1e280648e9 517 Pfam PF01476 LysM domain 336 378 2.2E-12 T 11-11-2016 IPR018392 LysM domain AUP74_RS11230 724a4eea5f37cf35657edb1e280648e9 517 Pfam PF01476 LysM domain 409 450 6.6E-11 T 11-11-2016 IPR018392 LysM domain AUP74_RS11230 724a4eea5f37cf35657edb1e280648e9 517 Pfam PF01476 LysM domain 467 508 2.7E-11 T 11-11-2016 IPR018392 LysM domain AUP74_RS11230 724a4eea5f37cf35657edb1e280648e9 517 SUPERFAMILY SSF54106 466 509 1.31E-10 T 11-11-2016 IPR018392 LysM domain AUP74_RS11230 724a4eea5f37cf35657edb1e280648e9 517 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 124 152 - T 11-11-2016 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 AUP74_RS14595 5f842af70f6b3dbc4db51457c6977e77 229 SUPERFAMILY SSF51206 15 147 1.27E-23 T 11-11-2016 IPR018490 Cyclic nucleotide-binding-like AUP74_RS14595 5f842af70f6b3dbc4db51457c6977e77 229 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 175 191 5.4E-10 T 11-11-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AUP74_RS14595 5f842af70f6b3dbc4db51457c6977e77 229 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 191 206 5.4E-10 T 11-11-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AUP74_RS14595 5f842af70f6b3dbc4db51457c6977e77 229 Pfam PF00027 Cyclic nucleotide-binding domain 36 119 7.2E-14 T 11-11-2016 IPR000595 Cyclic nucleotide-binding domain AUP74_RS14595 5f842af70f6b3dbc4db51457c6977e77 229 Pfam PF13545 Crp-like helix-turn-helix domain 152 225 2.0E-17 T 11-11-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AUP74_RS14595 5f842af70f6b3dbc4db51457c6977e77 229 SUPERFAMILY SSF46785 150 226 4.87E-14 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS14595 5f842af70f6b3dbc4db51457c6977e77 229 SMART SM00100 17 132 4.9E-8 T 11-11-2016 IPR000595 Cyclic nucleotide-binding domain AUP74_RS14595 5f842af70f6b3dbc4db51457c6977e77 229 Gene3D G3DSA:1.10.10.10 150 227 1.2E-18 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS14595 5f842af70f6b3dbc4db51457c6977e77 229 SMART SM00419 170 218 5.2E-14 T 11-11-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AUP74_RS14595 5f842af70f6b3dbc4db51457c6977e77 229 Gene3D G3DSA:2.60.120.10 15 142 1.6E-19 T 11-11-2016 IPR014710 RmlC-like jelly roll fold AUP74_RS14595 5f842af70f6b3dbc4db51457c6977e77 229 ProSitePatterns PS00042 Crp-type HTH domain signature. 177 200 - T 11-11-2016 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 AUP74_RS05480 60d55c4c148c460923c724832aadc422 248 Gene3D G3DSA:3.40.50.2300 3 125 2.5E-29 T 11-11-2016 AUP74_RS05480 60d55c4c148c460923c724832aadc422 248 Pfam PF04397 LytTr DNA-binding domain 151 243 4.9E-16 T 11-11-2016 IPR007492 LytTR DNA-binding domain GO:0003677 AUP74_RS05480 60d55c4c148c460923c724832aadc422 248 Gene3D G3DSA:2.40.50.40 142 203 1.1E-8 T 11-11-2016 AUP74_RS05480 60d55c4c148c460923c724832aadc422 248 SUPERFAMILY SSF52172 4 129 7.97E-29 T 11-11-2016 IPR011006 CheY-like superfamily AUP74_RS05480 60d55c4c148c460923c724832aadc422 248 SMART SM00850 148 244 1.6E-21 T 11-11-2016 IPR007492 LytTR DNA-binding domain GO:0003677 AUP74_RS05480 60d55c4c148c460923c724832aadc422 248 Pfam PF00072 Response regulator receiver domain 6 115 1.3E-22 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS05480 60d55c4c148c460923c724832aadc422 248 SMART SM00448 4 115 3.9E-20 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS00590 cbfcd0c78e858f70fe43410f1c4461a3 281 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 29 173 5.5E-14 T 11-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 AUP74_RS00590 cbfcd0c78e858f70fe43410f1c4461a3 281 Gene3D G3DSA:3.40.50.300 13 200 5.6E-32 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS00590 cbfcd0c78e858f70fe43410f1c4461a3 281 SUPERFAMILY SSF52540 9 243 4.63E-35 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS00590 cbfcd0c78e858f70fe43410f1c4461a3 281 SMART SM00382 25 183 1.1E-9 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS02875 65400861566edbab2c01911ed873cfc2 325 SUPERFAMILY SSF53474 75 323 2.01E-31 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS02875 65400861566edbab2c01911ed873cfc2 325 PRINTS PR00111 Alpha/beta hydrolase fold signature 158 171 9.8E-6 T 11-11-2016 IPR000073 Alpha/beta hydrolase fold-1 AUP74_RS02875 65400861566edbab2c01911ed873cfc2 325 PRINTS PR00111 Alpha/beta hydrolase fold signature 110 125 9.8E-6 T 11-11-2016 IPR000073 Alpha/beta hydrolase fold-1 AUP74_RS02875 65400861566edbab2c01911ed873cfc2 325 PRINTS PR00111 Alpha/beta hydrolase fold signature 265 279 9.8E-6 T 11-11-2016 IPR000073 Alpha/beta hydrolase fold-1 AUP74_RS02875 65400861566edbab2c01911ed873cfc2 325 Gene3D G3DSA:3.40.50.1820 72 323 9.9E-29 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS02875 65400861566edbab2c01911ed873cfc2 325 Pfam PF12146 Serine aminopeptidase, S33 81 309 1.6E-28 T 11-11-2016 IPR022742 Serine aminopeptidase, S33 AUP74_RS00510 1440bc7abde895fc0de17e3832f2791f 236 SUPERFAMILY SSF49354 26 152 5.23E-8 T 11-11-2016 IPR008962 PapD-like AUP74_RS00510 1440bc7abde895fc0de17e3832f2791f 236 Gene3D G3DSA:2.60.40.360 46 152 1.7E-4 T 11-11-2016 IPR008962 PapD-like AUP74_RS00510 1440bc7abde895fc0de17e3832f2791f 236 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 43 153 3.4E-6 T 11-11-2016 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 AUP74_RS16160 656566ff9be49c587e93291351185991 288 SUPERFAMILY SSF53474 6 284 4.27E-46 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS16160 656566ff9be49c587e93291351185991 288 Gene3D G3DSA:3.40.50.1820 5 272 1.7E-45 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS16160 656566ff9be49c587e93291351185991 288 Pfam PF12697 Alpha/beta hydrolase family 30 278 2.6E-12 T 11-11-2016 IPR000073 Alpha/beta hydrolase fold-1 AUP74_RS14085 a06c4616d271ff4fe9e8979a0d90c50b 468 SUPERFAMILY SSF53187 44 270 1.32E-35 T 11-11-2016 AUP74_RS14085 a06c4616d271ff4fe9e8979a0d90c50b 468 Gene3D G3DSA:3.40.630.10 44 294 8.3E-32 T 11-11-2016 AUP74_RS14085 a06c4616d271ff4fe9e8979a0d90c50b 468 Pfam PF00246 Zinc carboxypeptidase 52 155 2.7E-12 T 11-11-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 AUP74_RS13825 7e5a85631503f9d114bce59ab5628732 209 SUPERFAMILY SSF52833 1 84 7.48E-26 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS13825 7e5a85631503f9d114bce59ab5628732 209 Gene3D G3DSA:3.40.30.10 1 88 1.7E-30 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS13825 7e5a85631503f9d114bce59ab5628732 209 TIGRFAM TIGR01262 maiA: maleylacetoacetate isomerase 3 207 7.1E-84 T 11-11-2016 IPR005955 Maleylacetoacetate isomerase GO:0003824|GO:0005737|GO:0009072 Reactome: R-HSA-156590|Reactome: R-HSA-71182 AUP74_RS13825 7e5a85631503f9d114bce59ab5628732 209 Gene3D G3DSA:1.20.1050.10 89 206 3.4E-47 T 11-11-2016 IPR010987 Glutathione S-transferase, C-terminal-like AUP74_RS13825 7e5a85631503f9d114bce59ab5628732 209 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 79 1.6E-16 T 11-11-2016 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 AUP74_RS13825 7e5a85631503f9d114bce59ab5628732 209 SUPERFAMILY SSF47616 81 206 9.52E-31 T 11-11-2016 IPR010987 Glutathione S-transferase, C-terminal-like AUP74_RS05880 4a369719fbbe7c2d9f9e73c803d050f2 221 SUPERFAMILY SSF52317 3 218 2.29E-35 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS05880 4a369719fbbe7c2d9f9e73c803d050f2 221 Gene3D G3DSA:3.40.50.880 48 209 2.4E-34 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS05880 4a369719fbbe7c2d9f9e73c803d050f2 221 Pfam PF07722 Peptidase C26 48 201 3.0E-42 T 11-11-2016 IPR011697 Peptidase C26 GO:0006541|GO:0016787 AUP74_RS11160 8b34605dfe095f0c930d1e64c6968ba8 165 Gene3D G3DSA:2.60.40.790 3 139 6.9E-19 T 11-11-2016 IPR008978 HSP20-like chaperone AUP74_RS11160 8b34605dfe095f0c930d1e64c6968ba8 165 Pfam PF00011 Hsp20/alpha crystallin family 45 139 3.5E-21 T 11-11-2016 IPR002068 Alpha crystallin/Hsp20 domain AUP74_RS11160 8b34605dfe095f0c930d1e64c6968ba8 165 SUPERFAMILY SSF49764 33 138 2.58E-22 T 11-11-2016 IPR008978 HSP20-like chaperone AUP74_RS06845 a4b8b57b2130d104a40f51a1e7bf4549 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 24.86 T 11-11-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06845 a4b8b57b2130d104a40f51a1e7bf4549 92 SUPERFAMILY SSF54570 3 84 1.44E-34 T 11-11-2016 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06845 a4b8b57b2130d104a40f51a1e7bf4549 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 5.0E-23 T 11-11-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06845 a4b8b57b2130d104a40f51a1e7bf4549 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 5.0E-23 T 11-11-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06845 a4b8b57b2130d104a40f51a1e7bf4549 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 5.0E-23 T 11-11-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06845 a4b8b57b2130d104a40f51a1e7bf4549 92 PIRSF PIRSF002144 1 92 7.8E-31 T 11-11-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06845 a4b8b57b2130d104a40f51a1e7bf4549 92 Gene3D G3DSA:3.30.860.10 2 91 2.5E-39 T 11-11-2016 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06845 a4b8b57b2130d104a40f51a1e7bf4549 92 Pfam PF00203 Ribosomal protein S19 3 83 5.6E-36 T 11-11-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06845 a4b8b57b2130d104a40f51a1e7bf4549 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 2 91 3.9E-43 T 11-11-2016 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 AUP74_RS06845 a4b8b57b2130d104a40f51a1e7bf4549 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 11-11-2016 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS03630 64c7ce2184798bbd0633994e7a0b02ac 255 Pfam PF13505 Outer membrane protein beta-barrel domain 7 246 4.5E-14 T 11-11-2016 IPR027385 Outer membrane protein beta-barrel AUP74_RS03630 64c7ce2184798bbd0633994e7a0b02ac 255 Gene3D G3DSA:2.40.160.20 22 102 6.2E-28 T 11-11-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AUP74_RS03630 64c7ce2184798bbd0633994e7a0b02ac 255 Gene3D G3DSA:2.40.160.20 142 255 6.2E-28 T 11-11-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AUP74_RS03630 64c7ce2184798bbd0633994e7a0b02ac 255 SUPERFAMILY SSF56925 142 255 3.4E-25 T 11-11-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AUP74_RS03630 64c7ce2184798bbd0633994e7a0b02ac 255 SUPERFAMILY SSF56925 68 102 3.4E-25 T 11-11-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AUP74_RS03630 64c7ce2184798bbd0633994e7a0b02ac 255 SUPERFAMILY SSF56925 21 38 3.4E-25 T 11-11-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AUP74_RS06610 97ea7666b906f09d968336790dc0ab32 140 TIGRFAM TIGR00701 TIGR00701: TIGR00701 family protein 2 140 5.9E-44 T 11-11-2016 IPR014351 Conserved hypothetical protein CHP00701 AUP74_RS06610 97ea7666b906f09d968336790dc0ab32 140 Pfam PF03653 Uncharacterised protein family (UPF0093) 2 140 2.5E-53 T 11-11-2016 IPR005265 Uncharacterised protein family UPF0093 AUP74_RS06610 97ea7666b906f09d968336790dc0ab32 140 PIRSF PIRSF004638 1 140 5.9E-55 T 11-11-2016 IPR005265 Uncharacterised protein family UPF0093 AUP74_RS00915 f35ea1874670ef79a8d035eb0c00e1eb 261 SUPERFAMILY SSF74653 152 239 6.47E-18 T 11-11-2016 AUP74_RS00915 f35ea1874670ef79a8d035eb0c00e1eb 261 Gene3D G3DSA:3.30.1150.10 143 258 6.7E-20 T 11-11-2016 AUP74_RS00915 f35ea1874670ef79a8d035eb0c00e1eb 261 TIGRFAM TIGR02794 tolA_full: protein TolA 65 232 7.3E-21 T 11-11-2016 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0006810|GO:0016020 AUP74_RS00915 f35ea1874670ef79a8d035eb0c00e1eb 261 Pfam PF13103 TonB C terminal 167 233 4.4E-14 T 11-11-2016 IPR006260 TonB, C-terminal GO:0006810 AUP74_RS00915 f35ea1874670ef79a8d035eb0c00e1eb 261 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 180 234 4.7E-10 T 11-11-2016 IPR006260 TonB, C-terminal GO:0006810 AUP74_RS16845 3d1140dd86d9f805714c1d7ffd4428d4 131 Pfam PF04386 Stringent starvation protein B 3 119 1.1E-35 T 11-11-2016 IPR007481 Stringent starvation protein B AUP74_RS16845 3d1140dd86d9f805714c1d7ffd4428d4 131 PIRSF PIRSF005276 1 131 7.4E-50 T 11-11-2016 IPR007481 Stringent starvation protein B AUP74_RS16845 3d1140dd86d9f805714c1d7ffd4428d4 131 Gene3D G3DSA:2.30.30.220 1 106 1.2E-47 T 11-11-2016 IPR007481 Stringent starvation protein B AUP74_RS16845 3d1140dd86d9f805714c1d7ffd4428d4 131 SUPERFAMILY SSF101738 1 112 5.23E-45 T 11-11-2016 IPR007481 Stringent starvation protein B AUP74_RS11065 176a849b466c884abc5378d0c31c9de9 285 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 11-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AUP74_RS11065 176a849b466c884abc5378d0c31c9de9 285 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 193 5.4E-5 T 11-11-2016 AUP74_RS11065 176a849b466c884abc5378d0c31c9de9 285 Gene3D G3DSA:3.40.50.720 4 249 1.2E-56 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS11065 176a849b466c884abc5378d0c31c9de9 285 Pfam PF00106 short chain dehydrogenase 5 195 1.5E-45 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS11065 176a849b466c884abc5378d0c31c9de9 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 6.6E-21 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS11065 176a849b466c884abc5378d0c31c9de9 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 6.6E-21 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS11065 176a849b466c884abc5378d0c31c9de9 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 6.6E-21 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS11065 176a849b466c884abc5378d0c31c9de9 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 6.6E-21 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS11065 176a849b466c884abc5378d0c31c9de9 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 6.6E-21 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS11065 176a849b466c884abc5378d0c31c9de9 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.5E-8 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS11065 176a849b466c884abc5378d0c31c9de9 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.5E-8 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS11065 176a849b466c884abc5378d0c31c9de9 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.5E-8 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS11065 176a849b466c884abc5378d0c31c9de9 285 SUPERFAMILY SSF51735 4 260 5.28E-55 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS02360 ff095bdb36402809b7fac5fa579c8329 652 Pfam PF03734 L,D-transpeptidase catalytic domain 426 589 1.1E-30 T 11-11-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 AUP74_RS02360 ff095bdb36402809b7fac5fa579c8329 652 Gene3D G3DSA:2.40.440.10 423 470 7.9E-14 T 11-11-2016 AUP74_RS02360 ff095bdb36402809b7fac5fa579c8329 652 Gene3D G3DSA:2.40.440.10 533 580 7.9E-14 T 11-11-2016 AUP74_RS02360 ff095bdb36402809b7fac5fa579c8329 652 Gene3D G3DSA:1.10.101.10 322 406 1.9E-16 T 11-11-2016 IPR002477 Peptidoglycan binding-like AUP74_RS02360 ff095bdb36402809b7fac5fa579c8329 652 Pfam PF01471 Putative peptidoglycan binding domain 340 398 8.3E-10 T 11-11-2016 IPR002477 Peptidoglycan binding-like AUP74_RS02360 ff095bdb36402809b7fac5fa579c8329 652 SUPERFAMILY SSF141523 423 479 7.59E-21 T 11-11-2016 AUP74_RS02360 ff095bdb36402809b7fac5fa579c8329 652 SUPERFAMILY SSF141523 531 580 7.59E-21 T 11-11-2016 AUP74_RS02360 ff095bdb36402809b7fac5fa579c8329 652 SUPERFAMILY SSF47090 322 406 1.88E-14 T 11-11-2016 IPR002477 Peptidoglycan binding-like AUP74_RS09390 f7557dfc20e17570d53cdf0bb6e9f601 674 SUPERFAMILY SSF81901 358 561 3.14E-27 T 11-11-2016 AUP74_RS09390 f7557dfc20e17570d53cdf0bb6e9f601 674 Pfam PF08238 Sel1 repeat 271 297 0.9 T 11-11-2016 IPR006597 Sel1-like repeat AUP74_RS09390 f7557dfc20e17570d53cdf0bb6e9f601 674 Pfam PF08238 Sel1 repeat 592 627 3.5E-5 T 11-11-2016 IPR006597 Sel1-like repeat AUP74_RS09390 f7557dfc20e17570d53cdf0bb6e9f601 674 Pfam PF08238 Sel1 repeat 448 483 0.014 T 11-11-2016 IPR006597 Sel1-like repeat AUP74_RS09390 f7557dfc20e17570d53cdf0bb6e9f601 674 Pfam PF08238 Sel1 repeat 521 554 4.0E-7 T 11-11-2016 IPR006597 Sel1-like repeat AUP74_RS09390 f7557dfc20e17570d53cdf0bb6e9f601 674 Pfam PF08238 Sel1 repeat 573 591 0.062 T 11-11-2016 IPR006597 Sel1-like repeat AUP74_RS09390 f7557dfc20e17570d53cdf0bb6e9f601 674 Pfam PF08238 Sel1 repeat 488 519 2.1E-6 T 11-11-2016 IPR006597 Sel1-like repeat AUP74_RS09390 f7557dfc20e17570d53cdf0bb6e9f601 674 SMART SM00671 448 483 0.081 T 11-11-2016 IPR006597 Sel1-like repeat AUP74_RS09390 f7557dfc20e17570d53cdf0bb6e9f601 674 SMART SM00671 556 591 0.82 T 11-11-2016 IPR006597 Sel1-like repeat AUP74_RS09390 f7557dfc20e17570d53cdf0bb6e9f601 674 SMART SM00671 520 555 9.4E-8 T 11-11-2016 IPR006597 Sel1-like repeat AUP74_RS09390 f7557dfc20e17570d53cdf0bb6e9f601 674 SMART SM00671 592 627 2.3E-8 T 11-11-2016 IPR006597 Sel1-like repeat AUP74_RS09390 f7557dfc20e17570d53cdf0bb6e9f601 674 SMART SM00671 265 300 26.0 T 11-11-2016 IPR006597 Sel1-like repeat AUP74_RS09390 f7557dfc20e17570d53cdf0bb6e9f601 674 SMART SM00671 484 519 2.1E-4 T 11-11-2016 IPR006597 Sel1-like repeat AUP74_RS09390 f7557dfc20e17570d53cdf0bb6e9f601 674 SMART SM00671 378 410 230.0 T 11-11-2016 IPR006597 Sel1-like repeat AUP74_RS09390 f7557dfc20e17570d53cdf0bb6e9f601 674 Gene3D G3DSA:1.25.40.10 478 553 1.1E-22 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS09390 f7557dfc20e17570d53cdf0bb6e9f601 674 Gene3D G3DSA:1.25.40.10 554 634 6.3E-20 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS09390 f7557dfc20e17570d53cdf0bb6e9f601 674 Gene3D G3DSA:1.25.40.10 359 477 8.1E-14 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS09390 f7557dfc20e17570d53cdf0bb6e9f601 674 Gene3D G3DSA:1.25.40.10 194 347 5.7E-12 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS09390 f7557dfc20e17570d53cdf0bb6e9f601 674 SUPERFAMILY SSF81901 538 631 2.12E-19 T 11-11-2016 AUP74_RS09390 f7557dfc20e17570d53cdf0bb6e9f601 674 SUPERFAMILY SSF81901 202 387 4.32E-14 T 11-11-2016 AUP74_RS00275 30aef0c0e31924f799ad267aa9989195 605 SUPERFAMILY SSF143975 3 421 5.1E-137 T 11-11-2016 AUP74_RS00275 30aef0c0e31924f799ad267aa9989195 605 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 155 165 - T 11-11-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AUP74_RS00275 30aef0c0e31924f799ad267aa9989195 605 Pfam PF00920 Dehydratase family 67 601 1.1E-158 T 11-11-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AUP74_RS00275 30aef0c0e31924f799ad267aa9989195 605 SUPERFAMILY SSF52016 422 603 4.79E-58 T 11-11-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel AUP74_RS00275 30aef0c0e31924f799ad267aa9989195 605 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 508 519 - T 11-11-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AUP74_RS00275 30aef0c0e31924f799ad267aa9989195 605 TIGRFAM TIGR01196 edd: phosphogluconate dehydratase 3 604 1.2E-300 T 11-11-2016 IPR004786 6-phosphogluconate dehydratase GO:0004456|GO:0009255 KEGG: 00030+4.2.1.12 AUP74_RS02215 235bdc68c75e065f75b48eb44a5229ff 472 Pfam PF00483 Nucleotidyl transferase 4 288 6.8E-72 T 11-11-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 AUP74_RS02215 235bdc68c75e065f75b48eb44a5229ff 472 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 2 470 4.9E-229 T 11-11-2016 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 AUP74_RS02215 235bdc68c75e065f75b48eb44a5229ff 472 Gene3D G3DSA:2.60.120.10 359 471 3.6E-50 T 11-11-2016 IPR014710 RmlC-like jelly roll fold AUP74_RS02215 235bdc68c75e065f75b48eb44a5229ff 472 Gene3D G3DSA:3.90.550.10 2 273 3.6E-101 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases AUP74_RS02215 235bdc68c75e065f75b48eb44a5229ff 472 SUPERFAMILY SSF53448 1 283 3.9E-73 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases AUP74_RS02215 235bdc68c75e065f75b48eb44a5229ff 472 Pfam PF01050 Mannose-6-phosphate isomerase 317 467 3.8E-74 T 11-11-2016 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 AUP74_RS02215 235bdc68c75e065f75b48eb44a5229ff 472 SUPERFAMILY SSF51182 187 471 4.19E-94 T 11-11-2016 IPR011051 RmlC-like cupin domain AUP74_RS15515 2108881695cec788663ce353a5ae574f 212 PIRSF PIRSF006324 4 212 3.4E-46 T 11-11-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 AUP74_RS15515 2108881695cec788663ce353a5ae574f 212 Pfam PF01810 LysE type translocator 19 210 1.3E-25 T 11-11-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 AUP74_RS15535 d8da68161d391286c0fa8067d1082a9c 446 Gene3D G3DSA:3.40.50.720 13 158 7.2E-48 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS15535 d8da68161d391286c0fa8067d1082a9c 446 PIRSF PIRSF000098 13 444 3.0E-162 T 11-11-2016 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 AUP74_RS15535 d8da68161d391286c0fa8067d1082a9c 446 Pfam PF01842 ACT domain 364 430 1.9E-11 T 11-11-2016 IPR002912 ACT domain GO:0008152|GO:0016597 AUP74_RS15535 d8da68161d391286c0fa8067d1082a9c 446 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 193 215 - T 11-11-2016 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 AUP74_RS15535 d8da68161d391286c0fa8067d1082a9c 446 Pfam PF00742 Homoserine dehydrogenase 147 325 6.7E-65 T 11-11-2016 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 AUP74_RS15535 d8da68161d391286c0fa8067d1082a9c 446 SUPERFAMILY SSF51735 14 168 1.26E-33 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS15535 d8da68161d391286c0fa8067d1082a9c 446 Gene3D G3DSA:3.30.360.10 159 308 4.1E-57 T 11-11-2016 AUP74_RS15535 d8da68161d391286c0fa8067d1082a9c 446 Gene3D G3DSA:3.30.70.260 363 434 1.7E-9 T 11-11-2016 AUP74_RS15535 d8da68161d391286c0fa8067d1082a9c 446 SUPERFAMILY SSF55347 147 312 2.68E-54 T 11-11-2016 AUP74_RS15535 d8da68161d391286c0fa8067d1082a9c 446 SUPERFAMILY SSF55021 356 433 1.52E-10 T 11-11-2016 AUP74_RS15535 d8da68161d391286c0fa8067d1082a9c 446 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 22 139 1.3E-22 T 11-11-2016 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 AUP74_RS04765 f5dff8584eaad2aeceecb83f61d1c3d5 268 SUPERFAMILY SSF81345 5 264 3.27E-39 T 11-11-2016 IPR029022 ABC transporter, BtuC-like AUP74_RS04765 f5dff8584eaad2aeceecb83f61d1c3d5 268 Gene3D G3DSA:1.10.3470.10 50 264 2.6E-12 T 11-11-2016 IPR029022 ABC transporter, BtuC-like AUP74_RS04765 f5dff8584eaad2aeceecb83f61d1c3d5 268 Pfam PF00950 ABC 3 transport family 11 261 1.7E-70 T 11-11-2016 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 AUP74_RS15615 b5b5e9b7a044257d48c4643df3bbfe85 855 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 1 855 25.234 T 11-11-2016 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 AUP74_RS15615 b5b5e9b7a044257d48c4643df3bbfe85 855 Pfam PF07244 Surface antigen variable number repeat 347 420 7.4E-15 T 11-11-2016 IPR010827 Surface antigen variable number GO:0019867 AUP74_RS15615 b5b5e9b7a044257d48c4643df3bbfe85 855 Pfam PF07244 Surface antigen variable number repeat 92 171 2.7E-13 T 11-11-2016 IPR010827 Surface antigen variable number GO:0019867 AUP74_RS15615 b5b5e9b7a044257d48c4643df3bbfe85 855 Pfam PF07244 Surface antigen variable number repeat 265 343 2.4E-11 T 11-11-2016 IPR010827 Surface antigen variable number GO:0019867 AUP74_RS15615 b5b5e9b7a044257d48c4643df3bbfe85 855 Pfam PF07244 Surface antigen variable number repeat 175 262 3.3E-18 T 11-11-2016 IPR010827 Surface antigen variable number GO:0019867 AUP74_RS15615 b5b5e9b7a044257d48c4643df3bbfe85 855 PIRSF PIRSF006076 1 855 5.1E-254 T 11-11-2016 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 AUP74_RS15615 b5b5e9b7a044257d48c4643df3bbfe85 855 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 23 855 2.7E-254 T 11-11-2016 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 AUP74_RS15615 b5b5e9b7a044257d48c4643df3bbfe85 855 Pfam PF01103 Surface antigen 447 855 2.4E-84 T 11-11-2016 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020 AUP74_RS15615 b5b5e9b7a044257d48c4643df3bbfe85 855 Gene3D G3DSA:2.40.160.50 606 708 2.3E-27 T 11-11-2016 AUP74_RS15615 b5b5e9b7a044257d48c4643df3bbfe85 855 Gene3D G3DSA:2.40.160.50 396 569 2.3E-27 T 11-11-2016 AUP74_RS15615 b5b5e9b7a044257d48c4643df3bbfe85 855 Gene3D G3DSA:2.40.160.50 757 855 2.3E-27 T 11-11-2016 AUP74_RS13400 fb7b60d18a01319dfab67605c8441e5b 172 SMART SM00271 119 172 5.5E-6 T 11-11-2016 IPR001623 DnaJ domain AUP74_RS13400 fb7b60d18a01319dfab67605c8441e5b 172 SUPERFAMILY SSF46565 114 170 1.09E-14 T 11-11-2016 IPR001623 DnaJ domain AUP74_RS13400 fb7b60d18a01319dfab67605c8441e5b 172 Pfam PF00226 DnaJ domain 123 167 1.2E-6 T 11-11-2016 IPR001623 DnaJ domain AUP74_RS13400 fb7b60d18a01319dfab67605c8441e5b 172 Gene3D G3DSA:1.10.287.110 115 169 8.0E-15 T 11-11-2016 IPR001623 DnaJ domain AUP74_RS15140 656e4e9bbfb233eaa427f6faaa850b66 329 Pfam PF04381 Putative exonuclease, RdgC 1 298 2.0E-117 T 11-11-2016 IPR007476 Putative exonuclease, RdgC GO:0006310 AUP74_RS15140 656e4e9bbfb233eaa427f6faaa850b66 329 Hamap MF_00194 Recombination-associated protein RdgC [rdgC]. 1 301 36.479 T 11-11-2016 IPR007476 Putative exonuclease, RdgC GO:0006310 AUP74_RS07505 ea1fb73a38d10fdce1495a4691340b99 404 Pfam PF13533 Biotin-lipoyl like 85 131 4.4E-7 T 11-11-2016 AUP74_RS07505 ea1fb73a38d10fdce1495a4691340b99 404 SUPERFAMILY SSF111369 75 287 7.45E-27 T 11-11-2016 AUP74_RS07505 ea1fb73a38d10fdce1495a4691340b99 404 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 168 279 2.8E-18 T 11-11-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AUP74_RS07505 ea1fb73a38d10fdce1495a4691340b99 404 Gene3D G3DSA:2.40.50.100 178 210 2.2E-12 T 11-11-2016 AUP74_RS07505 ea1fb73a38d10fdce1495a4691340b99 404 Gene3D G3DSA:2.40.50.100 84 117 2.2E-12 T 11-11-2016 AUP74_RS07505 ea1fb73a38d10fdce1495a4691340b99 404 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 66 362 4.1E-45 T 11-11-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 AUP74_RS06105 b0449c836c36ee082b29087a65245be3 389 SUPERFAMILY SSF47203 235 387 4.19E-48 T 11-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AUP74_RS06105 b0449c836c36ee082b29087a65245be3 389 SUPERFAMILY SSF56645 6 249 5.89E-85 T 11-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 AUP74_RS06105 b0449c836c36ee082b29087a65245be3 389 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 129 224 5.3E-26 T 11-11-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 AUP74_RS06105 b0449c836c36ee082b29087a65245be3 389 Gene3D G3DSA:1.20.140.10 224 387 6.4E-65 T 11-11-2016 AUP74_RS06105 b0449c836c36ee082b29087a65245be3 389 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 343 362 - T 11-11-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AUP74_RS06105 b0449c836c36ee082b29087a65245be3 389 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 125 6.0E-38 T 11-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 AUP74_RS06105 b0449c836c36ee082b29087a65245be3 389 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 131 143 - T 11-11-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AUP74_RS06105 b0449c836c36ee082b29087a65245be3 389 Gene3D G3DSA:2.40.110.10 128 223 1.4E-39 T 11-11-2016 AUP74_RS06105 b0449c836c36ee082b29087a65245be3 389 Gene3D G3DSA:1.10.540.10 9 126 8.2E-44 T 11-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 AUP74_RS06105 b0449c836c36ee082b29087a65245be3 389 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 237 384 1.4E-42 T 11-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AUP74_RS15860 7c6ee37e7754576b354abb435ed3cf04 341 SMART SM00829 12 338 7.6E-4 T 11-11-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AUP74_RS15860 7c6ee37e7754576b354abb435ed3cf04 341 TIGRFAM TIGR00692 tdh: L-threonine 3-dehydrogenase 3 340 4.0E-175 T 11-11-2016 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00260+1.1.1.103|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-7378 AUP74_RS15860 7c6ee37e7754576b354abb435ed3cf04 341 Pfam PF00107 Zinc-binding dehydrogenase 174 301 2.3E-26 T 11-11-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AUP74_RS15860 7c6ee37e7754576b354abb435ed3cf04 341 Hamap MF_00627 L-threonine 3-dehydrogenase [tdh]. 1 340 60.673 T 11-11-2016 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00260+1.1.1.103|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-7378 AUP74_RS15860 7c6ee37e7754576b354abb435ed3cf04 341 Gene3D G3DSA:3.40.50.720 173 287 1.2E-35 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS15860 7c6ee37e7754576b354abb435ed3cf04 341 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 134 1.2E-31 T 11-11-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AUP74_RS15860 7c6ee37e7754576b354abb435ed3cf04 341 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 11-11-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 AUP74_RS15860 7c6ee37e7754576b354abb435ed3cf04 341 Gene3D G3DSA:3.90.180.10 1 172 1.8E-50 T 11-11-2016 IPR011032 GroES-like AUP74_RS15860 7c6ee37e7754576b354abb435ed3cf04 341 SUPERFAMILY SSF50129 1 173 1.67E-53 T 11-11-2016 IPR011032 GroES-like AUP74_RS15860 7c6ee37e7754576b354abb435ed3cf04 341 SUPERFAMILY SSF51735 141 305 3.82E-37 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS16905 26404a6e410f1fe93b38e935553e058e 212 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 142 163 - T 11-11-2016 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 AUP74_RS16905 26404a6e410f1fe93b38e935553e058e 212 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 2 207 52.69 T 11-11-2016 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 AUP74_RS16905 26404a6e410f1fe93b38e935553e058e 212 Pfam PF01634 ATP phosphoribosyltransferase 52 203 1.1E-46 T 11-11-2016 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 AUP74_RS16905 26404a6e410f1fe93b38e935553e058e 212 Gene3D G3DSA:3.40.190.10 3 117 3.6E-31 T 11-11-2016 AUP74_RS16905 26404a6e410f1fe93b38e935553e058e 212 SUPERFAMILY SSF53850 2 205 2.61E-63 T 11-11-2016 AUP74_RS16905 26404a6e410f1fe93b38e935553e058e 212 Gene3D G3DSA:3.40.190.10 118 176 2.1E-26 T 11-11-2016 AUP74_RS16905 26404a6e410f1fe93b38e935553e058e 212 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 3 183 1.9E-54 T 11-11-2016 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 AUP74_RS14965 9a9eb596b8769ea7be4ac0e452918ea5 391 SUPERFAMILY SSF51556 57 347 1.02E-68 T 11-11-2016 IPR032466 Metal-dependent hydrolase AUP74_RS14965 9a9eb596b8769ea7be4ac0e452918ea5 391 Pfam PF01979 Amidohydrolase family 54 374 6.8E-14 T 11-11-2016 IPR006680 Amidohydrolase-related GO:0016787 AUP74_RS14965 9a9eb596b8769ea7be4ac0e452918ea5 391 Gene3D G3DSA:2.30.40.10 331 379 1.0E-9 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS14965 9a9eb596b8769ea7be4ac0e452918ea5 391 SUPERFAMILY SSF51338 347 384 1.39E-17 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS14965 9a9eb596b8769ea7be4ac0e452918ea5 391 SUPERFAMILY SSF51338 4 56 1.39E-17 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS14965 9a9eb596b8769ea7be4ac0e452918ea5 391 TIGRFAM TIGR01975 isoAsp_dipep: beta-aspartyl peptidase 5 389 2.0E-137 T 11-11-2016 IPR010229 Peptidase M38, beta-aspartyl dipeptidase GO:0008798 AUP74_RS14965 9a9eb596b8769ea7be4ac0e452918ea5 391 PIRSF PIRSF001238 3 391 5.4E-146 T 11-11-2016 IPR010229 Peptidase M38, beta-aspartyl dipeptidase GO:0008798 AUP74_RS14965 9a9eb596b8769ea7be4ac0e452918ea5 391 Gene3D G3DSA:3.20.20.140 65 330 1.0E-111 T 11-11-2016 AUP74_RS14965 9a9eb596b8769ea7be4ac0e452918ea5 391 Gene3D G3DSA:2.30.40.10 5 64 3.0E-14 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS13105 71d6a961860df80b42c5fc4b1792e36f 1005 Pfam PF10150 Ribonuclease E/G family 122 391 3.5E-96 T 11-11-2016 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 AUP74_RS13105 71d6a961860df80b42c5fc4b1792e36f 1005 Gene3D G3DSA:2.40.50.140 31 126 5.4E-34 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS13105 71d6a961860df80b42c5fc4b1792e36f 1005 Pfam PF00575 S1 RNA binding domain 36 119 1.8E-14 T 11-11-2016 IPR003029 S1 domain GO:0003676 AUP74_RS13105 71d6a961860df80b42c5fc4b1792e36f 1005 SUPERFAMILY SSF50249 40 126 4.0E-18 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS13105 71d6a961860df80b42c5fc4b1792e36f 1005 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 425 3.2E-165 T 11-11-2016 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 AUP74_RS13105 71d6a961860df80b42c5fc4b1792e36f 1005 SMART SM00316 37 120 2.0E-11 T 11-11-2016 IPR022967 RNA-binding domain, S1 AUP74_RS13105 71d6a961860df80b42c5fc4b1792e36f 1005 Hamap MF_00970 Ribonuclease E [rne]. 1 940 32.928 T 11-11-2016 IPR028878 Ribonuclease E GO:0006396|GO:0008995 AUP74_RS09550 9e83d7305ceeed605f668ca8fd6f2fda 451 Gene3D G3DSA:1.20.1250.20 259 444 5.6E-14 T 11-11-2016 AUP74_RS09550 9e83d7305ceeed605f668ca8fd6f2fda 451 Gene3D G3DSA:1.20.1250.20 17 214 1.7E-10 T 11-11-2016 AUP74_RS09550 9e83d7305ceeed605f668ca8fd6f2fda 451 SUPERFAMILY SSF103473 13 443 4.84E-33 T 11-11-2016 IPR020846 Major facilitator superfamily domain AUP74_RS09550 9e83d7305ceeed605f668ca8fd6f2fda 451 Pfam PF07690 Major Facilitator Superfamily 24 397 9.5E-14 T 11-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AUP74_RS05155 39b051f7d0df19f2fd8267ecedac708f 523 SUPERFAMILY SSF51905 5 186 3.55E-12 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS05155 39b051f7d0df19f2fd8267ecedac708f 523 Pfam PF12831 FAD dependent oxidoreductase 6 497 7.9E-84 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS05155 39b051f7d0df19f2fd8267ecedac708f 523 Gene3D G3DSA:3.50.50.60 96 174 3.1E-9 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS05155 39b051f7d0df19f2fd8267ecedac708f 523 Gene3D G3DSA:3.50.50.60 5 53 3.1E-9 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS05915 eb9fef1577cf7cba1c117dfa94ec1fe9 887 Pfam PF00311 Phosphoenolpyruvate carboxylase 135 887 5.2E-280 T 11-11-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AUP74_RS05915 eb9fef1577cf7cba1c117dfa94ec1fe9 887 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 544 556 - T 11-11-2016 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AUP74_RS05915 eb9fef1577cf7cba1c117dfa94ec1fe9 887 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 2 887 18.709 T 11-11-2016 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AUP74_RS05915 eb9fef1577cf7cba1c117dfa94ec1fe9 887 SUPERFAMILY SSF51621 10 887 5.18E-302 T 11-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AUP74_RS05915 eb9fef1577cf7cba1c117dfa94ec1fe9 887 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 192 208 5.8E-69 T 11-11-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AUP74_RS05915 eb9fef1577cf7cba1c117dfa94ec1fe9 887 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 389 409 5.8E-69 T 11-11-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AUP74_RS05915 eb9fef1577cf7cba1c117dfa94ec1fe9 887 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 139 152 5.8E-69 T 11-11-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AUP74_RS05915 eb9fef1577cf7cba1c117dfa94ec1fe9 887 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 584 613 5.8E-69 T 11-11-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AUP74_RS05915 eb9fef1577cf7cba1c117dfa94ec1fe9 887 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 716 742 5.8E-69 T 11-11-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AUP74_RS05915 eb9fef1577cf7cba1c117dfa94ec1fe9 887 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 251 266 5.8E-69 T 11-11-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AUP74_RS05915 eb9fef1577cf7cba1c117dfa94ec1fe9 887 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 542 562 5.8E-69 T 11-11-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AUP74_RS05915 eb9fef1577cf7cba1c117dfa94ec1fe9 887 Gene3D G3DSA:1.20.1440.90 279 391 5.7E-29 T 11-11-2016 AUP74_RS05915 eb9fef1577cf7cba1c117dfa94ec1fe9 887 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 140 151 - T 11-11-2016 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AUP74_RS00720 add2dba7f77aa8fff6f90a86dfa93690 273 Pfam PF01925 Sulfite exporter TauE/SafE 8 263 9.4E-56 T 11-11-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 AUP74_RS05470 00bf4d6f6a20195646e39f166c8c8d93 477 Gene3D G3DSA:1.10.40.30 393 450 3.2E-32 T 11-11-2016 AUP74_RS05470 00bf4d6f6a20195646e39f166c8c8d93 477 PRINTS PR00145 Argininosuccinate lyase family signature 212 228 5.2E-66 T 11-11-2016 AUP74_RS05470 00bf4d6f6a20195646e39f166c8c8d93 477 PRINTS PR00145 Argininosuccinate lyase family signature 250 274 5.2E-66 T 11-11-2016 AUP74_RS05470 00bf4d6f6a20195646e39f166c8c8d93 477 PRINTS PR00145 Argininosuccinate lyase family signature 161 181 5.2E-66 T 11-11-2016 AUP74_RS05470 00bf4d6f6a20195646e39f166c8c8d93 477 PRINTS PR00145 Argininosuccinate lyase family signature 120 142 5.2E-66 T 11-11-2016 AUP74_RS05470 00bf4d6f6a20195646e39f166c8c8d93 477 PRINTS PR00145 Argininosuccinate lyase family signature 294 310 5.2E-66 T 11-11-2016 AUP74_RS05470 00bf4d6f6a20195646e39f166c8c8d93 477 PRINTS PR00145 Argininosuccinate lyase family signature 329 348 5.2E-66 T 11-11-2016 AUP74_RS05470 00bf4d6f6a20195646e39f166c8c8d93 477 SUPERFAMILY SSF48557 22 473 2.51E-154 T 11-11-2016 IPR008948 L-Aspartase-like GO:0003824 AUP74_RS05470 00bf4d6f6a20195646e39f166c8c8d93 477 Gene3D G3DSA:1.20.200.10 126 392 3.3E-107 T 11-11-2016 AUP74_RS05470 00bf4d6f6a20195646e39f166c8c8d93 477 Pfam PF00206 Lyase 25 319 5.6E-78 T 11-11-2016 IPR022761 Fumarate lyase, N-terminal AUP74_RS05470 00bf4d6f6a20195646e39f166c8c8d93 477 Hamap MF_00006 Argininosuccinate lyase [argH]. 21 472 43.898 T 11-11-2016 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AUP74_RS05470 00bf4d6f6a20195646e39f166c8c8d93 477 Pfam PF14698 Argininosuccinate lyase C-terminal 382 450 9.6E-26 T 11-11-2016 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AUP74_RS05470 00bf4d6f6a20195646e39f166c8c8d93 477 PRINTS PR00149 Fumarate lyase superfamily signature 166 184 1.1E-29 T 11-11-2016 IPR000362 Fumarate lyase family AUP74_RS05470 00bf4d6f6a20195646e39f166c8c8d93 477 PRINTS PR00149 Fumarate lyase superfamily signature 294 310 1.1E-29 T 11-11-2016 IPR000362 Fumarate lyase family AUP74_RS05470 00bf4d6f6a20195646e39f166c8c8d93 477 PRINTS PR00149 Fumarate lyase superfamily signature 250 277 1.1E-29 T 11-11-2016 IPR000362 Fumarate lyase family AUP74_RS05470 00bf4d6f6a20195646e39f166c8c8d93 477 PRINTS PR00149 Fumarate lyase superfamily signature 121 139 1.1E-29 T 11-11-2016 IPR000362 Fumarate lyase family AUP74_RS05470 00bf4d6f6a20195646e39f166c8c8d93 477 Gene3D G3DSA:1.10.275.10 21 125 1.6E-42 T 11-11-2016 IPR024083 Fumarase/histidase, N-terminal AUP74_RS05470 00bf4d6f6a20195646e39f166c8c8d93 477 ProSitePatterns PS00163 Fumarate lyases signature. 294 303 - T 11-11-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 AUP74_RS05470 00bf4d6f6a20195646e39f166c8c8d93 477 TIGRFAM TIGR00838 argH: argininosuccinate lyase 22 474 4.4E-191 T 11-11-2016 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AUP74_RS14910 c7d12f6ab28e8183e511edd42227298a 240 SUPERFAMILY SSF51161 81 198 1.14E-38 T 11-11-2016 IPR011004 Trimeric LpxA-like AUP74_RS14910 c7d12f6ab28e8183e511edd42227298a 240 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 145 173 - T 11-11-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 AUP74_RS14910 c7d12f6ab28e8183e511edd42227298a 240 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 82 117 0.0037 T 11-11-2016 IPR001451 Hexapeptide repeat AUP74_RS14910 c7d12f6ab28e8183e511edd42227298a 240 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 136 171 2.8E-10 T 11-11-2016 IPR001451 Hexapeptide repeat AUP74_RS14910 c7d12f6ab28e8183e511edd42227298a 240 Gene3D G3DSA:2.160.10.10 48 217 8.5E-43 T 11-11-2016 AUP74_RS04905 eab748c43a3be1eb8e8082faaa109367 388 Pfam PF07584 Aerotolerance regulator N-terminal 8 81 5.9E-13 T 11-11-2016 IPR024163 Aerotolerance regulator, N-terminal AUP74_RS04905 eab748c43a3be1eb8e8082faaa109367 388 TIGRFAM TIGR02226 two_anch: N-terminal double-transmembrane domain 9 86 2.2E-16 T 11-11-2016 IPR011933 Double transmembrane domain AUP74_RS10880 13892e8452143e69e01600ad54017f2e 222 TIGRFAM TIGR01190 ccmB: heme exporter protein CcmB 7 217 3.8E-78 T 11-11-2016 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria AUP74_RS10880 13892e8452143e69e01600ad54017f2e 222 PIRSF PIRSF002764 1 221 2.4E-76 T 11-11-2016 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria AUP74_RS10880 13892e8452143e69e01600ad54017f2e 222 Pfam PF03379 CcmB protein 6 218 2.6E-75 T 11-11-2016 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 AUP74_RS10880 13892e8452143e69e01600ad54017f2e 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 194 217 5.4E-61 T 11-11-2016 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 AUP74_RS10880 13892e8452143e69e01600ad54017f2e 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 77 100 5.4E-61 T 11-11-2016 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 AUP74_RS10880 13892e8452143e69e01600ad54017f2e 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 102 120 5.4E-61 T 11-11-2016 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 AUP74_RS10880 13892e8452143e69e01600ad54017f2e 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 28 49 5.4E-61 T 11-11-2016 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 AUP74_RS10880 13892e8452143e69e01600ad54017f2e 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 54 71 5.4E-61 T 11-11-2016 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 AUP74_RS10880 13892e8452143e69e01600ad54017f2e 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 157 176 5.4E-61 T 11-11-2016 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 AUP74_RS09900 36a47f51837259be6c87aa391fc7b531 248 Pfam PF14451 Mut7-C ubiquitin 2 80 1.8E-32 T 11-11-2016 IPR027798 Ubiquitin Mut7-C domain AUP74_RS09900 36a47f51837259be6c87aa391fc7b531 248 Gene3D G3DSA:3.10.20.30 30 76 4.7E-9 T 11-11-2016 IPR012675 Beta-grasp domain AUP74_RS09900 36a47f51837259be6c87aa391fc7b531 248 SUPERFAMILY SSF54285 26 75 5.23E-6 T 11-11-2016 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp AUP74_RS09900 36a47f51837259be6c87aa391fc7b531 248 Pfam PF01927 Mut7-C RNAse domain 95 238 2.0E-49 T 11-11-2016 IPR002782 Mut7-C RNAse domain AUP74_RS13275 6cc4f839e503542e7f902c08628bc47a 185 PIRSF PIRSF030820 12 185 8.5E-49 T 11-11-2016 IPR008318 Uncharacterised conserved protein UCP030820 AUP74_RS13275 6cc4f839e503542e7f902c08628bc47a 185 Pfam PF06073 Bacterial protein of unknown function (DUF934) 73 179 1.3E-38 T 11-11-2016 IPR008318 Uncharacterised conserved protein UCP030820 AUP74_RS08230 d725f35c23d0daa54c2c930fe85cfdb3 140 Gene3D G3DSA:3.90.1590.10 4 108 1.6E-22 T 11-11-2016 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 AUP74_RS08230 d725f35c23d0daa54c2c930fe85cfdb3 140 SUPERFAMILY SSF51316 5 112 5.13E-30 T 11-11-2016 IPR011057 Mss4-like AUP74_RS08230 d725f35c23d0daa54c2c930fe85cfdb3 140 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 35 116 2.2E-11 T 11-11-2016 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 AUP74_RS09555 60f7ce47e62d91d857d1775ba871707f 111 SUPERFAMILY SSF46767 15 95 5.23E-24 T 11-11-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 AUP74_RS09555 60f7ce47e62d91d857d1775ba871707f 111 Gene3D G3DSA:1.10.10.10 16 95 3.7E-23 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS09555 60f7ce47e62d91d857d1775ba871707f 111 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 19 88 1.9E-13 T 11-11-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 AUP74_RS09555 60f7ce47e62d91d857d1775ba871707f 111 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 19 95 1.7E-24 T 11-11-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 AUP74_RS04705 95090cff351eb8aff9a555f74541ad81 74 Pfam PF11137 Protein of unknown function (DUF2909) 3 64 4.3E-17 T 11-11-2016 IPR021313 Protein of unknown function DUF2909 AUP74_RS04145 7d978daae7222454587eeec88c05331d 292 TIGRFAM TIGR01474 ubiA_proteo: 4-hydroxybenzoate polyprenyl transferase 14 290 1.4E-104 T 11-11-2016 IPR006370 4-hydroxybenzoate polyprenyltransferase GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 AUP74_RS04145 7d978daae7222454587eeec88c05331d 292 Hamap MF_01635 4-hydroxybenzoate octaprenyltransferase [ubiA]. 4 290 29.648 T 11-11-2016 IPR031103 4-hydroxybenzoate octaprenyltransferase GO:0004659|GO:0006744|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 AUP74_RS04145 7d978daae7222454587eeec88c05331d 292 Pfam PF01040 UbiA prenyltransferase family 30 272 8.8E-63 T 11-11-2016 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 AUP74_RS04145 7d978daae7222454587eeec88c05331d 292 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 69 91 - T 11-11-2016 IPR030470 UbiA prenyltransferase conserved site AUP74_RS16595 67d90cecd09bd6ebcdd6275f53a4bed9 79 ProDom PD056452 UNCHARACTERIZED BACTERIA SIMILAR YPEB CYTOPLASMIC VCA0163 PRODUCT STM2426 GENE YPO2988 15 68 2.0E-17 T 11-11-2016 IPR024530 Putative quorum-sensing-regulated virulence factor AUP74_RS16595 67d90cecd09bd6ebcdd6275f53a4bed9 79 Pfam PF12843 Putative quorum-sensing-regulated virulence factor 4 68 2.2E-29 T 11-11-2016 IPR024530 Putative quorum-sensing-regulated virulence factor AUP74_RS11350 58938bc1e7dc28c3b3a0695e1f8d3266 462 Pfam PF00041 Fibronectin type III domain 363 442 7.7E-6 T 11-11-2016 IPR003961 Fibronectin type III GO:0005515 AUP74_RS11350 58938bc1e7dc28c3b3a0695e1f8d3266 462 Gene3D G3DSA:2.60.40.10 364 442 3.6E-10 T 11-11-2016 IPR013783 Immunoglobulin-like fold AUP74_RS11350 58938bc1e7dc28c3b3a0695e1f8d3266 462 Pfam PF04389 Peptidase family M28 114 313 5.8E-18 T 11-11-2016 IPR007484 Peptidase M28 AUP74_RS11350 58938bc1e7dc28c3b3a0695e1f8d3266 462 SUPERFAMILY SSF53187 35 360 1.74E-45 T 11-11-2016 AUP74_RS11350 58938bc1e7dc28c3b3a0695e1f8d3266 462 Gene3D G3DSA:3.40.630.10 31 363 2.3E-44 T 11-11-2016 AUP74_RS11350 58938bc1e7dc28c3b3a0695e1f8d3266 462 SUPERFAMILY SSF49265 357 444 8.27E-12 T 11-11-2016 IPR003961 Fibronectin type III GO:0005515 AUP74_RS15065 76a8b2d3789cb24c9b946e2fff20e213 338 Pfam PF03481 Putative GTP-binding controlling metal-binding 194 316 3.5E-15 T 11-11-2016 IPR005145 Putative GTP-binding controlling metal-binding domain AUP74_RS15065 76a8b2d3789cb24c9b946e2fff20e213 338 Gene3D G3DSA:3.90.870.10 5 199 4.8E-69 T 11-11-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain AUP74_RS15065 76a8b2d3789cb24c9b946e2fff20e213 338 Pfam PF01300 Telomere recombination 16 191 1.6E-52 T 11-11-2016 IPR006070 YrdC-like domain GO:0003725 AUP74_RS15065 76a8b2d3789cb24c9b946e2fff20e213 338 SUPERFAMILY SSF55821 10 204 2.17E-57 T 11-11-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain AUP74_RS15065 76a8b2d3789cb24c9b946e2fff20e213 338 PIRSF PIRSF004930 1 323 2.5E-96 T 11-11-2016 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 AUP74_RS15065 76a8b2d3789cb24c9b946e2fff20e213 338 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 5 201 2.2E-56 T 11-11-2016 IPR006070 YrdC-like domain GO:0003725 AUP74_RS12910 520b15946a078961599ce2821c4ba6ad 97 Pfam PF03992 Antibiotic biosynthesis monooxygenase 6 77 7.1E-13 T 11-11-2016 IPR007138 Antibiotic biosynthesis monooxygenase domain AUP74_RS12910 520b15946a078961599ce2821c4ba6ad 97 Gene3D G3DSA:3.30.70.900 6 95 4.5E-19 T 11-11-2016 AUP74_RS12910 520b15946a078961599ce2821c4ba6ad 97 SUPERFAMILY SSF54909 4 95 1.84E-26 T 11-11-2016 IPR011008 Dimeric alpha-beta barrel AUP74_RS00525 7469562922babcd2541f5102a7fde71f 401 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 355 365 - T 11-11-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 AUP74_RS00525 7469562922babcd2541f5102a7fde71f 401 SUPERFAMILY SSF51905 3 300 1.94E-28 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS00525 7469562922babcd2541f5102a7fde71f 401 Pfam PF01266 FAD dependent oxidoreductase 6 361 2.4E-41 T 11-11-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AUP74_RS00525 7469562922babcd2541f5102a7fde71f 401 Gene3D G3DSA:3.50.50.60 3 279 1.4E-29 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS00525 7469562922babcd2541f5102a7fde71f 401 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 79 91 4.9E-15 T 11-11-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 AUP74_RS00525 7469562922babcd2541f5102a7fde71f 401 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 34 46 4.9E-15 T 11-11-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 AUP74_RS00525 7469562922babcd2541f5102a7fde71f 401 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 350 362 4.9E-15 T 11-11-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 AUP74_RS00525 7469562922babcd2541f5102a7fde71f 401 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 5 17 4.9E-15 T 11-11-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 AUP74_RS00525 7469562922babcd2541f5102a7fde71f 401 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 318 324 4.9E-15 T 11-11-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 AUP74_RS07585 a941c404d33513481a548300da1a13b5 543 ProSitePatterns PS00455 Putative AMP-binding domain signature. 182 193 - T 11-11-2016 IPR020845 AMP-binding, conserved site AUP74_RS07585 a941c404d33513481a548300da1a13b5 543 Gene3D G3DSA:3.30.300.30 433 532 1.9E-25 T 11-11-2016 AUP74_RS07585 a941c404d33513481a548300da1a13b5 543 Pfam PF00501 AMP-binding enzyme 19 438 1.2E-81 T 11-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 AUP74_RS07585 a941c404d33513481a548300da1a13b5 543 Gene3D G3DSA:2.30.38.10 359 432 1.9E-18 T 11-11-2016 AUP74_RS07585 a941c404d33513481a548300da1a13b5 543 SUPERFAMILY SSF56801 9 535 2.22E-128 T 11-11-2016 AUP74_RS07585 a941c404d33513481a548300da1a13b5 543 Pfam PF13193 AMP-binding enzyme C-terminal domain 447 522 1.1E-15 T 11-11-2016 IPR025110 AMP-binding enzyme C-terminal domain AUP74_RS07585 a941c404d33513481a548300da1a13b5 543 Gene3D G3DSA:3.40.50.980 48 188 1.1E-29 T 11-11-2016 AUP74_RS07585 a941c404d33513481a548300da1a13b5 543 Gene3D G3DSA:3.40.50.980 189 341 1.5E-36 T 11-11-2016 AUP74_RS07120 6fdfed0620722565aaf2f5c5b21d86ed 1034 Pfam PF13519 von Willebrand factor type A domain 51 147 1.9E-6 T 11-11-2016 IPR002035 von Willebrand factor, type A AUP74_RS07120 6fdfed0620722565aaf2f5c5b21d86ed 1034 SUPERFAMILY SSF53300 262 325 7.95E-13 T 11-11-2016 IPR002035 von Willebrand factor, type A AUP74_RS07120 6fdfed0620722565aaf2f5c5b21d86ed 1034 SUPERFAMILY SSF53300 50 161 7.95E-13 T 11-11-2016 IPR002035 von Willebrand factor, type A AUP74_RS07120 6fdfed0620722565aaf2f5c5b21d86ed 1034 SUPERFAMILY SSF53300 209 227 7.95E-13 T 11-11-2016 IPR002035 von Willebrand factor, type A AUP74_RS07120 6fdfed0620722565aaf2f5c5b21d86ed 1034 SMART SM00327 48 319 1.2E-4 T 11-11-2016 IPR002035 von Willebrand factor, type A AUP74_RS07120 6fdfed0620722565aaf2f5c5b21d86ed 1034 Pfam PF05567 Neisseria PilC beta-propeller domain 477 861 6.3E-59 T 11-11-2016 IPR008707 PilC beta-propeller domain AUP74_RS07120 6fdfed0620722565aaf2f5c5b21d86ed 1034 Gene3D G3DSA:3.40.50.410 261 324 6.9E-7 T 11-11-2016 IPR002035 von Willebrand factor, type A AUP74_RS07120 6fdfed0620722565aaf2f5c5b21d86ed 1034 Gene3D G3DSA:3.40.50.410 50 177 6.9E-7 T 11-11-2016 IPR002035 von Willebrand factor, type A AUP74_RS05125 0e3616e3555e37c545bec40e2bb2f7e6 420 Gene3D G3DSA:3.40.190.10 159 343 4.7E-33 T 11-11-2016 AUP74_RS05125 0e3616e3555e37c545bec40e2bb2f7e6 420 Pfam PF01547 Bacterial extracellular solute-binding protein 44 324 3.1E-34 T 11-11-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 AUP74_RS05125 0e3616e3555e37c545bec40e2bb2f7e6 420 Gene3D G3DSA:3.40.190.10 38 158 3.0E-19 T 11-11-2016 AUP74_RS05125 0e3616e3555e37c545bec40e2bb2f7e6 420 SUPERFAMILY SSF53850 22 411 7.25E-69 T 11-11-2016 AUP74_RS08170 28b7e92ae0160c5f0f2e4e31ab6e4a79 379 Pfam PF03929 PepSY-associated TM region 7 357 3.5E-62 T 11-11-2016 IPR005625 PepSY-associated TM protein AUP74_RS01380 1f49cc7b644b3298aa181be81b85ad38 188 SUPERFAMILY SSF101874 19 187 1.1E-55 T 11-11-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like AUP74_RS01380 1f49cc7b644b3298aa181be81b85ad38 188 Pfam PF04264 YceI-like domain 22 184 6.5E-41 T 11-11-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like AUP74_RS01380 1f49cc7b644b3298aa181be81b85ad38 188 SMART SM00867 21 186 5.0E-71 T 11-11-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like AUP74_RS01380 1f49cc7b644b3298aa181be81b85ad38 188 Gene3D G3DSA:2.40.128.110 19 187 9.3E-60 T 11-11-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like AUP74_RS14010 5751114bb4de848ba743883d03aa4cf6 151 Gene3D G3DSA:3.90.1720.10 3 136 3.8E-14 T 11-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain AUP74_RS14010 5751114bb4de848ba743883d03aa4cf6 151 SUPERFAMILY SSF54001 59 130 3.78E-11 T 11-11-2016 AUP74_RS14010 5751114bb4de848ba743883d03aa4cf6 151 Pfam PF00877 NlpC/P60 family 72 131 6.8E-6 T 11-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain AUP74_RS16900 352e27268591eeec56cda8b9941babc2 434 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 233 265 - T 11-11-2016 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 AUP74_RS16900 352e27268591eeec56cda8b9941babc2 434 Gene3D G3DSA:3.40.50.1980 30 243 4.1E-79 T 11-11-2016 AUP74_RS16900 352e27268591eeec56cda8b9941babc2 434 PIRSF PIRSF000099 1 434 5.8E-164 T 11-11-2016 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AUP74_RS16900 352e27268591eeec56cda8b9941babc2 434 SUPERFAMILY SSF53720 30 431 1.96E-87 T 11-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AUP74_RS16900 352e27268591eeec56cda8b9941babc2 434 PRINTS PR00083 Histidinol dehydrogenase signature 255 274 6.8E-88 T 11-11-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AUP74_RS16900 352e27268591eeec56cda8b9941babc2 434 PRINTS PR00083 Histidinol dehydrogenase signature 365 383 6.8E-88 T 11-11-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AUP74_RS16900 352e27268591eeec56cda8b9941babc2 434 PRINTS PR00083 Histidinol dehydrogenase signature 174 200 6.8E-88 T 11-11-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AUP74_RS16900 352e27268591eeec56cda8b9941babc2 434 PRINTS PR00083 Histidinol dehydrogenase signature 233 254 6.8E-88 T 11-11-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AUP74_RS16900 352e27268591eeec56cda8b9941babc2 434 PRINTS PR00083 Histidinol dehydrogenase signature 204 229 6.8E-88 T 11-11-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AUP74_RS16900 352e27268591eeec56cda8b9941babc2 434 PRINTS PR00083 Histidinol dehydrogenase signature 324 349 6.8E-88 T 11-11-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AUP74_RS16900 352e27268591eeec56cda8b9941babc2 434 PRINTS PR00083 Histidinol dehydrogenase signature 36 60 6.8E-88 T 11-11-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AUP74_RS16900 352e27268591eeec56cda8b9941babc2 434 PRINTS PR00083 Histidinol dehydrogenase signature 140 166 6.8E-88 T 11-11-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AUP74_RS16900 352e27268591eeec56cda8b9941babc2 434 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 8 431 41.85 T 11-11-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AUP74_RS16900 352e27268591eeec56cda8b9941babc2 434 Pfam PF00815 Histidinol dehydrogenase 28 431 6.1E-171 T 11-11-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AUP74_RS16900 352e27268591eeec56cda8b9941babc2 434 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 36 430 1.0E-164 T 11-11-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AUP74_RS01160 0826953d0a0861855c6f232ad3238ee0 962 Gene3D G3DSA:2.170.130.10 12 145 6.4E-31 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS01160 0826953d0a0861855c6f232ad3238ee0 962 Pfam PF00593 TonB dependent receptor 614 959 6.0E-19 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS01160 0826953d0a0861855c6f232ad3238ee0 962 Gene3D G3DSA:2.40.170.20 146 205 4.6E-70 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS01160 0826953d0a0861855c6f232ad3238ee0 962 Gene3D G3DSA:2.40.170.20 762 962 4.6E-70 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS01160 0826953d0a0861855c6f232ad3238ee0 962 Gene3D G3DSA:2.40.170.20 354 421 4.6E-70 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS01160 0826953d0a0861855c6f232ad3238ee0 962 Gene3D G3DSA:2.40.170.20 257 308 4.6E-70 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS01160 0826953d0a0861855c6f232ad3238ee0 962 Gene3D G3DSA:2.40.170.20 471 728 4.6E-70 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS01160 0826953d0a0861855c6f232ad3238ee0 962 SUPERFAMILY SSF56935 474 711 9.89E-92 T 11-11-2016 AUP74_RS01160 0826953d0a0861855c6f232ad3238ee0 962 SUPERFAMILY SSF56935 898 962 9.89E-92 T 11-11-2016 AUP74_RS01160 0826953d0a0861855c6f232ad3238ee0 962 SUPERFAMILY SSF56935 759 870 9.89E-92 T 11-11-2016 AUP74_RS01160 0826953d0a0861855c6f232ad3238ee0 962 SUPERFAMILY SSF56935 9 202 9.89E-92 T 11-11-2016 AUP74_RS01160 0826953d0a0861855c6f232ad3238ee0 962 SUPERFAMILY SSF56935 275 326 9.89E-92 T 11-11-2016 AUP74_RS01160 0826953d0a0861855c6f232ad3238ee0 962 SUPERFAMILY SSF56935 371 437 9.89E-92 T 11-11-2016 AUP74_RS01160 0826953d0a0861855c6f232ad3238ee0 962 Pfam PF07715 TonB-dependent Receptor Plug Domain 32 143 1.4E-23 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS01765 36d93fccad4563806afe1b6ad3adccfe 641 SUPERFAMILY SSF50956 323 639 1.44E-61 T 11-11-2016 AUP74_RS01765 36d93fccad4563806afe1b6ad3adccfe 641 SUPERFAMILY SSF50956 57 252 1.44E-14 T 11-11-2016 AUP74_RS01765 36d93fccad4563806afe1b6ad3adccfe 641 Pfam PF02333 Phytase 314 638 3.3E-67 T 11-11-2016 IPR003431 Beta propeller phytase GO:0016158 KEGG: 00562+3.1.3.8|MetaCyc: PWY-4702 AUP74_RS01765 36d93fccad4563806afe1b6ad3adccfe 641 Gene3D G3DSA:2.120.10.20 61 282 2.9E-24 T 11-11-2016 IPR003431 Beta propeller phytase GO:0016158 KEGG: 00562+3.1.3.8|MetaCyc: PWY-4702 AUP74_RS01765 36d93fccad4563806afe1b6ad3adccfe 641 Gene3D G3DSA:2.120.10.20 323 640 2.3E-101 T 11-11-2016 IPR003431 Beta propeller phytase GO:0016158 KEGG: 00562+3.1.3.8|MetaCyc: PWY-4702 AUP74_RS11380 e28187e5dee01746fe7476eb1528941c 194 PIRSF PIRSF033239 1 194 1.5E-50 T 11-11-2016 IPR010331 Exopolysaccharide synthesis, ExoD AUP74_RS11380 e28187e5dee01746fe7476eb1528941c 194 Pfam PF06055 Exopolysaccharide synthesis, ExoD 8 190 1.2E-47 T 11-11-2016 IPR010331 Exopolysaccharide synthesis, ExoD AUP74_RS03230 31073ea61b91e3039e677353ec543226 243 Gene3D G3DSA:3.20.20.70 1 238 5.2E-87 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS03230 31073ea61b91e3039e677353ec543226 243 Pfam PF00977 Histidine biosynthesis protein 3 229 3.1E-80 T 11-11-2016 IPR006062 Histidine biosynthesis GO:0000105 AUP74_RS03230 31073ea61b91e3039e677353ec543226 243 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 233 7.7E-80 T 11-11-2016 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 AUP74_RS03230 31073ea61b91e3039e677353ec543226 243 SUPERFAMILY SSF51366 1 237 2.9E-77 T 11-11-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 AUP74_RS03230 31073ea61b91e3039e677353ec543226 243 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 237 35.999 T 11-11-2016 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 AUP74_RS01395 b770c0c4ed6b771ab4111e641570b145 297 Pfam PF13431 Tetratricopeptide repeat 207 239 6.8E-6 T 11-11-2016 AUP74_RS01395 b770c0c4ed6b771ab4111e641570b145 297 Gene3D G3DSA:1.25.40.10 173 252 2.2E-17 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS01395 b770c0c4ed6b771ab4111e641570b145 297 Gene3D G3DSA:1.25.40.10 70 82 2.2E-17 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS01395 b770c0c4ed6b771ab4111e641570b145 297 SMART SM00028 219 252 0.0012 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS01395 b770c0c4ed6b771ab4111e641570b145 297 SMART SM00028 185 218 0.038 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS01395 b770c0c4ed6b771ab4111e641570b145 297 SUPERFAMILY SSF48452 171 252 8.13E-18 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS08260 18a58988d403b3164801dad8e0bc07d0 160 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 89 100 - T 11-11-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AUP74_RS08260 18a58988d403b3164801dad8e0bc07d0 160 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 5 133 5.1E-43 T 11-11-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AUP74_RS08260 18a58988d403b3164801dad8e0bc07d0 160 Gene3D G3DSA:3.30.70.560 5 155 2.9E-57 T 11-11-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AUP74_RS08260 18a58988d403b3164801dad8e0bc07d0 160 SUPERFAMILY SSF55083 5 156 1.1E-52 T 11-11-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AUP74_RS08260 18a58988d403b3164801dad8e0bc07d0 160 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 6 133 1.8E-37 T 11-11-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AUP74_RS16330 50c32b875b5bcb3adb8d85a3cc254219 622 Gene3D G3DSA:3.40.50.720 400 473 4.5E-7 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS16330 50c32b875b5bcb3adb8d85a3cc254219 622 SUPERFAMILY SSF51735 402 487 2.36E-7 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS16330 50c32b875b5bcb3adb8d85a3cc254219 622 Pfam PF00999 Sodium/hydrogen exchanger family 14 387 6.0E-38 T 11-11-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 AUP74_RS16330 50c32b875b5bcb3adb8d85a3cc254219 622 Pfam PF02254 TrkA-N domain 403 485 9.3E-6 T 11-11-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 AUP74_RS07195 690c4fc9c4a12d21b54bb32dee9b737a 368 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 40 351 1.4E-72 T 11-11-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 AUP74_RS07195 690c4fc9c4a12d21b54bb32dee9b737a 368 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 52 265 3.7E-31 T 11-11-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AUP74_RS07195 690c4fc9c4a12d21b54bb32dee9b737a 368 Gene3D G3DSA:2.40.50.100 66 98 1.2E-13 T 11-11-2016 AUP74_RS07195 690c4fc9c4a12d21b54bb32dee9b737a 368 Gene3D G3DSA:2.40.50.100 159 190 1.2E-13 T 11-11-2016 AUP74_RS07195 690c4fc9c4a12d21b54bb32dee9b737a 368 SUPERFAMILY SSF111369 55 270 3.53E-43 T 11-11-2016 AUP74_RS13420 b18a07b3956fd3b32c88b9a3333d7791 970 Gene3D G3DSA:3.30.830.10 812 951 1.9E-6 T 11-11-2016 IPR011237 Peptidase M16 domain GO:0046872 AUP74_RS13420 b18a07b3956fd3b32c88b9a3333d7791 970 Gene3D G3DSA:3.30.830.10 31 241 2.2E-40 T 11-11-2016 IPR011237 Peptidase M16 domain GO:0046872 AUP74_RS13420 b18a07b3956fd3b32c88b9a3333d7791 970 SUPERFAMILY SSF63411 16 241 7.33E-49 T 11-11-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AUP74_RS13420 b18a07b3956fd3b32c88b9a3333d7791 970 SUPERFAMILY SSF63411 259 521 3.14E-54 T 11-11-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AUP74_RS13420 b18a07b3956fd3b32c88b9a3333d7791 970 SUPERFAMILY SSF63411 784 952 3.67E-37 T 11-11-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AUP74_RS13420 b18a07b3956fd3b32c88b9a3333d7791 970 Pfam PF05193 Peptidase M16 inactive domain 204 390 5.3E-13 T 11-11-2016 IPR007863 Peptidase M16, C-terminal AUP74_RS13420 b18a07b3956fd3b32c88b9a3333d7791 970 Pfam PF05193 Peptidase M16 inactive domain 790 885 9.9E-6 T 11-11-2016 IPR007863 Peptidase M16, C-terminal AUP74_RS13420 b18a07b3956fd3b32c88b9a3333d7791 970 SMART SM01264 464 711 8.5E-92 T 11-11-2016 IPR013578 Peptidase M16C associated GO:0006508 AUP74_RS13420 b18a07b3956fd3b32c88b9a3333d7791 970 SUPERFAMILY SSF63411 520 772 4.58E-60 T 11-11-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AUP74_RS13420 b18a07b3956fd3b32c88b9a3333d7791 970 Pfam PF08367 Peptidase M16C associated 464 711 4.4E-62 T 11-11-2016 IPR013578 Peptidase M16C associated GO:0006508 AUP74_RS13420 b18a07b3956fd3b32c88b9a3333d7791 970 Pfam PF00675 Insulinase (Peptidase family M16) 54 139 1.6E-9 T 11-11-2016 IPR011765 Peptidase M16, N-terminal AUP74_RS00145 82817d7b4b712f8c9b8c9e7c37cc3c84 415 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 132 398 1.1E-52 T 11-11-2016 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 AUP74_RS00145 82817d7b4b712f8c9b8c9e7c37cc3c84 415 Gene3D G3DSA:3.40.630.10 122 314 1.7E-21 T 11-11-2016 AUP74_RS00145 82817d7b4b712f8c9b8c9e7c37cc3c84 415 SUPERFAMILY SSF53187 121 399 1.39E-66 T 11-11-2016 AUP74_RS10695 b2901a4ecaf8477f6b70c12a0b38973f 740 Gene3D G3DSA:1.10.420.10 591 712 6.4E-50 T 11-11-2016 AUP74_RS10695 b2901a4ecaf8477f6b70c12a0b38973f 740 PRINTS PR00458 Haem peroxidase superfamily signature 259 274 5.9E-18 T 11-11-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AUP74_RS10695 b2901a4ecaf8477f6b70c12a0b38973f 740 PRINTS PR00458 Haem peroxidase superfamily signature 643 658 5.9E-18 T 11-11-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AUP74_RS10695 b2901a4ecaf8477f6b70c12a0b38973f 740 PRINTS PR00458 Haem peroxidase superfamily signature 174 186 5.9E-18 T 11-11-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AUP74_RS10695 b2901a4ecaf8477f6b70c12a0b38973f 740 PRINTS PR00458 Haem peroxidase superfamily signature 96 110 5.9E-18 T 11-11-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AUP74_RS10695 b2901a4ecaf8477f6b70c12a0b38973f 740 PRINTS PR00458 Haem peroxidase superfamily signature 156 173 5.9E-18 T 11-11-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AUP74_RS10695 b2901a4ecaf8477f6b70c12a0b38973f 740 Gene3D G3DSA:1.10.420.10 252 274 7.6E-45 T 11-11-2016 AUP74_RS10695 b2901a4ecaf8477f6b70c12a0b38973f 740 Gene3D G3DSA:1.10.420.10 310 409 7.6E-45 T 11-11-2016 AUP74_RS10695 b2901a4ecaf8477f6b70c12a0b38973f 740 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 267 290 3.7E-46 T 11-11-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 AUP74_RS10695 b2901a4ecaf8477f6b70c12a0b38973f 740 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 32 54 3.7E-46 T 11-11-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 AUP74_RS10695 b2901a4ecaf8477f6b70c12a0b38973f 740 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 73 98 3.7E-46 T 11-11-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 AUP74_RS10695 b2901a4ecaf8477f6b70c12a0b38973f 740 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 482 508 3.7E-46 T 11-11-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 AUP74_RS10695 b2901a4ecaf8477f6b70c12a0b38973f 740 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 58 71 3.7E-46 T 11-11-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 AUP74_RS10695 b2901a4ecaf8477f6b70c12a0b38973f 740 Pfam PF00141 Peroxidase 87 398 4.5E-50 T 11-11-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AUP74_RS10695 b2901a4ecaf8477f6b70c12a0b38973f 740 Pfam PF00141 Peroxidase 404 710 9.6E-41 T 11-11-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AUP74_RS10695 b2901a4ecaf8477f6b70c12a0b38973f 740 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 259 269 - T 11-11-2016 IPR019793 Peroxidases heam-ligand binding site Reactome: R-HSA-2408557 AUP74_RS10695 b2901a4ecaf8477f6b70c12a0b38973f 740 Gene3D G3DSA:1.10.520.10 434 590 3.0E-64 T 11-11-2016 AUP74_RS10695 b2901a4ecaf8477f6b70c12a0b38973f 740 Gene3D G3DSA:1.10.520.10 716 737 3.0E-64 T 11-11-2016 AUP74_RS10695 b2901a4ecaf8477f6b70c12a0b38973f 740 ProSitePatterns PS00436 Peroxidases active site signature. 96 107 - T 11-11-2016 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 AUP74_RS10695 b2901a4ecaf8477f6b70c12a0b38973f 740 SUPERFAMILY SSF48113 28 432 1.31E-148 T 11-11-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 AUP74_RS10695 b2901a4ecaf8477f6b70c12a0b38973f 740 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 27 739 0.0 T 11-11-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 AUP74_RS10695 b2901a4ecaf8477f6b70c12a0b38973f 740 SUPERFAMILY SSF48113 432 737 3.09E-116 T 11-11-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 AUP74_RS10695 b2901a4ecaf8477f6b70c12a0b38973f 740 Hamap MF_01961 Catalase-peroxidase [katG]. 21 738 41.312 T 11-11-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 AUP74_RS10695 b2901a4ecaf8477f6b70c12a0b38973f 740 Gene3D G3DSA:1.10.520.10 227 251 3.3E-71 T 11-11-2016 AUP74_RS10695 b2901a4ecaf8477f6b70c12a0b38973f 740 Gene3D G3DSA:1.10.520.10 53 195 3.3E-71 T 11-11-2016 AUP74_RS15030 848a9ce1b607f5aa2db25bd76559f096 404 Pfam PF02080 TrkA-C domain 309 370 3.5E-10 T 11-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AUP74_RS15030 848a9ce1b607f5aa2db25bd76559f096 404 SUPERFAMILY SSF116726 298 374 2.09E-15 T 11-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AUP74_RS15030 848a9ce1b607f5aa2db25bd76559f096 404 Gene3D G3DSA:3.30.1490.20 112 171 2.2E-8 T 11-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 AUP74_RS15030 848a9ce1b607f5aa2db25bd76559f096 404 Gene3D G3DSA:3.40.50.20 8 111 5.4E-15 T 11-11-2016 IPR016185 Pre-ATP-grasp domain AUP74_RS15030 848a9ce1b607f5aa2db25bd76559f096 404 Gene3D G3DSA:3.30.70.1450 306 372 5.1E-14 T 11-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AUP74_RS15030 848a9ce1b607f5aa2db25bd76559f096 404 SUPERFAMILY SSF56059 98 287 1.68E-47 T 11-11-2016 AUP74_RS15030 848a9ce1b607f5aa2db25bd76559f096 404 Pfam PF08443 RimK-like ATP-grasp domain 98 286 1.3E-57 T 11-11-2016 IPR013651 ATP-grasp fold, RimK-type AUP74_RS15030 848a9ce1b607f5aa2db25bd76559f096 404 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 2 286 3.5E-77 T 11-11-2016 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 AUP74_RS15030 848a9ce1b607f5aa2db25bd76559f096 404 Gene3D G3DSA:3.30.470.20 172 277 9.0E-34 T 11-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 AUP74_RS10145 2d197608fe1cd1f016e320420ebacb4d 182 SUPERFAMILY SSF53254 1 174 9.82E-25 T 11-11-2016 IPR029033 Histidine phosphatase superfamily AUP74_RS10145 2d197608fe1cd1f016e320420ebacb4d 182 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 174 3.6E-19 T 11-11-2016 IPR013078 Histidine phosphatase superfamily, clade-1 AUP74_RS10145 2d197608fe1cd1f016e320420ebacb4d 182 Gene3D G3DSA:3.40.50.1240 3 177 2.6E-22 T 11-11-2016 IPR029033 Histidine phosphatase superfamily AUP74_RS10145 2d197608fe1cd1f016e320420ebacb4d 182 SMART SM00855 3 138 3.1E-14 T 11-11-2016 IPR013078 Histidine phosphatase superfamily, clade-1 AUP74_RS10035 a25736b629f2e4154f664123ec655f9a 1176 SMART SM00481 6 73 6.0E-26 T 11-11-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 AUP74_RS10035 a25736b629f2e4154f664123ec655f9a 1176 SUPERFAMILY SSF89550 5 261 1.06E-17 T 11-11-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AUP74_RS10035 a25736b629f2e4154f664123ec655f9a 1176 Gene3D G3DSA:3.20.20.140 4 255 3.1E-25 T 11-11-2016 AUP74_RS10035 a25736b629f2e4154f664123ec655f9a 1176 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 293 735 6.5E-175 T 11-11-2016 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS10035 a25736b629f2e4154f664123ec655f9a 1176 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 5 1041 0.0 T 11-11-2016 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS10035 a25736b629f2e4154f664123ec655f9a 1176 Gene3D G3DSA:1.10.150.280 825 885 5.7E-6 T 11-11-2016 AUP74_RS10035 a25736b629f2e4154f664123ec655f9a 1176 Pfam PF14579 Helix-hairpin-helix motif 812 894 6.4E-24 T 11-11-2016 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS10035 a25736b629f2e4154f664123ec655f9a 1176 Pfam PF02811 PHP domain 7 170 6.2E-44 T 11-11-2016 IPR004013 PHP domain GO:0003824 AUP74_RS10035 a25736b629f2e4154f664123ec655f9a 1176 Gene3D G3DSA:2.40.50.140 992 1085 2.6E-9 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS14040 31818288118cff215d572ba6e6d451b2 311 SMART SM00797 26 303 5.6E-119 T 11-11-2016 IPR003778 Carboxyltransferase domain, subdomain A and B AUP74_RS14040 31818288118cff215d572ba6e6d451b2 311 Gene3D G3DSA:2.40.100.10 232 295 1.8E-5 T 11-11-2016 IPR029000 Cyclophilin-like domain AUP74_RS14040 31818288118cff215d572ba6e6d451b2 311 SUPERFAMILY SSF50891 188 291 6.45E-10 T 11-11-2016 IPR029000 Cyclophilin-like domain AUP74_RS14040 31818288118cff215d572ba6e6d451b2 311 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 10 302 2.0E-79 T 11-11-2016 IPR003778 Carboxyltransferase domain, subdomain A and B AUP74_RS14040 31818288118cff215d572ba6e6d451b2 311 Pfam PF02626 Allophanate hydrolase subunit 2 27 286 6.7E-83 T 11-11-2016 IPR003778 Carboxyltransferase domain, subdomain A and B AUP74_RS12680 9c38a2b3e2c5c8af80bbed2a9708ec24 87 SUPERFAMILY SSF47336 1 81 1.57E-10 T 11-11-2016 IPR009081 Phosphopantetheine binding ACP domain AUP74_RS12680 9c38a2b3e2c5c8af80bbed2a9708ec24 87 Pfam PF00550 Phosphopantetheine attachment site 16 76 1.9E-6 T 11-11-2016 IPR009081 Phosphopantetheine binding ACP domain AUP74_RS12680 9c38a2b3e2c5c8af80bbed2a9708ec24 87 Gene3D G3DSA:1.10.1200.10 1 80 2.1E-11 T 11-11-2016 IPR009081 Phosphopantetheine binding ACP domain AUP74_RS11645 0367b45f2b255c27ff8f216d73ed6694 281 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 280 34.817 T 11-11-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 AUP74_RS11645 0367b45f2b255c27ff8f216d73ed6694 281 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 122 7.8E-39 T 11-11-2016 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 AUP74_RS11645 0367b45f2b255c27ff8f216d73ed6694 281 Gene3D G3DSA:3.40.192.10 7 142 4.3E-41 T 11-11-2016 AUP74_RS11645 0367b45f2b255c27ff8f216d73ed6694 281 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 129 278 4.0E-57 T 11-11-2016 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 AUP74_RS11645 0367b45f2b255c27ff8f216d73ed6694 281 SUPERFAMILY SSF53223 1 123 5.66E-39 T 11-11-2016 AUP74_RS11645 0367b45f2b255c27ff8f216d73ed6694 281 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 257 265 - T 11-11-2016 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 AUP74_RS11645 0367b45f2b255c27ff8f216d73ed6694 281 SUPERFAMILY SSF51735 130 277 1.47E-43 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS11645 0367b45f2b255c27ff8f216d73ed6694 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 76 103 9.0E-51 T 11-11-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 AUP74_RS11645 0367b45f2b255c27ff8f216d73ed6694 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 156 176 9.0E-51 T 11-11-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 AUP74_RS11645 0367b45f2b255c27ff8f216d73ed6694 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 35 57 9.0E-51 T 11-11-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 AUP74_RS11645 0367b45f2b255c27ff8f216d73ed6694 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 111 132 9.0E-51 T 11-11-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 AUP74_RS11645 0367b45f2b255c27ff8f216d73ed6694 281 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 205 234 9.0E-51 T 11-11-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 AUP74_RS11645 0367b45f2b255c27ff8f216d73ed6694 281 Gene3D G3DSA:3.40.50.720 143 261 1.5E-45 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS04910 d9f3e31e5d7e5c4b2459e36558d1881b 300 SUPERFAMILY SSF53300 75 195 1.14E-6 T 11-11-2016 IPR002035 von Willebrand factor, type A AUP74_RS04910 d9f3e31e5d7e5c4b2459e36558d1881b 300 Pfam PF01882 Protein of unknown function DUF58 39 127 7.7E-19 T 11-11-2016 IPR002881 Domain of unknown function DUF58 AUP74_RS02155 9f04ca22a5db127393df5410cee6e226 181 Pfam PF06853 Protein of unknown function (DUF1249) 44 169 8.3E-29 T 11-11-2016 IPR009659 Protein of unknown function DUF1249 AUP74_RS05695 cc8e5895bf282d1b841a466f0dc5d994 120 SUPERFAMILY SSF52172 1 119 3.84E-37 T 11-11-2016 IPR011006 CheY-like superfamily AUP74_RS05695 cc8e5895bf282d1b841a466f0dc5d994 120 SMART SM00448 2 115 2.0E-36 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS05695 cc8e5895bf282d1b841a466f0dc5d994 120 Pfam PF00072 Response regulator receiver domain 4 115 1.9E-27 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS05695 cc8e5895bf282d1b841a466f0dc5d994 120 Gene3D G3DSA:3.40.50.2300 1 119 2.7E-38 T 11-11-2016 AUP74_RS12490 81772483d140022fd6c2b0c22fa7fff0 787 Gene3D G3DSA:2.40.170.20 186 642 1.9E-57 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS12490 81772483d140022fd6c2b0c22fa7fff0 787 Gene3D G3DSA:2.40.170.20 675 785 1.9E-57 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS12490 81772483d140022fd6c2b0c22fa7fff0 787 Pfam PF00593 TonB dependent receptor 520 785 3.2E-11 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS12490 81772483d140022fd6c2b0c22fa7fff0 787 SUPERFAMILY SSF56935 434 640 5.49E-71 T 11-11-2016 AUP74_RS12490 81772483d140022fd6c2b0c22fa7fff0 787 SUPERFAMILY SSF56935 674 786 5.49E-71 T 11-11-2016 AUP74_RS12490 81772483d140022fd6c2b0c22fa7fff0 787 SUPERFAMILY SSF56935 33 403 5.49E-71 T 11-11-2016 AUP74_RS12490 81772483d140022fd6c2b0c22fa7fff0 787 Gene3D G3DSA:2.170.130.10 31 180 9.6E-12 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS07620 c2d92c2207cb57b5ea3d6b4fce4ad059 264 Pfam PF01618 MotA/TolQ/ExbB proton channel family 133 250 2.2E-17 T 11-11-2016 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 AUP74_RS07160 14f8bd8b441eea98ff6477091df9b3b5 469 SUPERFAMILY SSF46689 351 467 8.96E-14 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS07160 14f8bd8b441eea98ff6477091df9b3b5 469 Pfam PF02954 Bacterial regulatory protein, Fis family 425 465 9.2E-15 T 11-11-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AUP74_RS07160 14f8bd8b441eea98ff6477091df9b3b5 469 SMART SM00382 157 300 2.1E-8 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS07160 14f8bd8b441eea98ff6477091df9b3b5 469 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 223 238 - T 11-11-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 AUP74_RS07160 14f8bd8b441eea98ff6477091df9b3b5 469 Gene3D G3DSA:3.40.50.2300 6 131 1.3E-31 T 11-11-2016 AUP74_RS07160 14f8bd8b441eea98ff6477091df9b3b5 469 SUPERFAMILY SSF52172 5 179 1.85E-39 T 11-11-2016 IPR011006 CheY-like superfamily AUP74_RS07160 14f8bd8b441eea98ff6477091df9b3b5 469 Gene3D G3DSA:1.10.8.60 310 384 3.1E-24 T 11-11-2016 AUP74_RS07160 14f8bd8b441eea98ff6477091df9b3b5 469 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 431 448 3.3E-11 T 11-11-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AUP74_RS07160 14f8bd8b441eea98ff6477091df9b3b5 469 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 448 468 3.3E-11 T 11-11-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AUP74_RS07160 14f8bd8b441eea98ff6477091df9b3b5 469 Pfam PF00158 Sigma-54 interaction domain 138 304 4.5E-67 T 11-11-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 AUP74_RS07160 14f8bd8b441eea98ff6477091df9b3b5 469 Gene3D G3DSA:1.10.10.60 415 468 5.7E-16 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS07160 14f8bd8b441eea98ff6477091df9b3b5 469 SMART SM00448 3 115 4.6E-32 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS07160 14f8bd8b441eea98ff6477091df9b3b5 469 Pfam PF00072 Response regulator receiver domain 6 114 4.9E-27 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS07160 14f8bd8b441eea98ff6477091df9b3b5 469 Gene3D G3DSA:3.40.50.300 137 309 4.2E-57 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS07160 14f8bd8b441eea98ff6477091df9b3b5 469 SUPERFAMILY SSF52540 138 378 6.96E-66 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS07160 14f8bd8b441eea98ff6477091df9b3b5 469 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 350 359 - T 11-11-2016 IPR025944 Sigma-54 interaction domain, conserved site AUP74_RS11155 00d0ce7e876b6f29c1b6db5e2684e0fd 198 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 13 190 6.5E-26 T 11-11-2016 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 AUP74_RS11155 00d0ce7e876b6f29c1b6db5e2684e0fd 198 SUPERFAMILY SSF55144 13 192 2.09E-30 T 11-11-2016 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase AUP74_RS11155 00d0ce7e876b6f29c1b6db5e2684e0fd 198 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 13 191 16.455 T 11-11-2016 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 AUP74_RS11155 00d0ce7e876b6f29c1b6db5e2684e0fd 198 Gene3D G3DSA:3.90.1140.10 14 193 5.5E-34 T 11-11-2016 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase AUP74_RS11155 00d0ce7e876b6f29c1b6db5e2684e0fd 198 Pfam PF02834 LigT like Phosphoesterase 37 100 7.5E-7 T 11-11-2016 IPR014051 Phosphoesterase, HXTX AUP74_RS04540 6e4f8674afa1f86cfc7214afc3bd17ba 411 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 6 79 3.0E-18 T 11-11-2016 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 AUP74_RS04540 6e4f8674afa1f86cfc7214afc3bd17ba 411 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 206 408 3.1E-57 T 11-11-2016 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 AUP74_RS12465 24443edc1d008628c0f97c913adce82d 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 2.6E-10 T 11-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AUP74_RS12465 24443edc1d008628c0f97c913adce82d 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 2.6E-10 T 11-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AUP74_RS12465 24443edc1d008628c0f97c913adce82d 217 Pfam PF08361 MAATS-type transcriptional repressor, C-terminal region 84 203 9.7E-26 T 11-11-2016 IPR013572 Transcription regulator MAATS, C-terminal GO:0003677 AUP74_RS12465 24443edc1d008628c0f97c913adce82d 217 Gene3D G3DSA:1.10.10.60 3 60 2.2E-20 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS12465 24443edc1d008628c0f97c913adce82d 217 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 58 - T 11-11-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AUP74_RS12465 24443edc1d008628c0f97c913adce82d 217 Gene3D G3DSA:1.10.357.10 61 211 3.8E-23 T 11-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 AUP74_RS12465 24443edc1d008628c0f97c913adce82d 217 SUPERFAMILY SSF48498 85 202 1.11E-16 T 11-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AUP74_RS12465 24443edc1d008628c0f97c913adce82d 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 7.2E-15 T 11-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AUP74_RS12465 24443edc1d008628c0f97c913adce82d 217 SUPERFAMILY SSF46689 3 66 1.18E-17 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS11750 0185dcb480e5f110e678f539dec4ad35 575 Pfam PF13584 Oxygen tolerance 41 483 4.8E-100 T 11-11-2016 IPR025738 Aerotolerance-related protein BatD AUP74_RS16450 0251a6fa5e7777ca62f732fd2d24cebd 270 SUPERFAMILY SSF56300 10 182 2.64E-36 T 11-11-2016 IPR029052 Metallo-dependent phosphatase-like AUP74_RS16450 0251a6fa5e7777ca62f732fd2d24cebd 270 SUPERFAMILY SSF56300 215 253 2.64E-36 T 11-11-2016 IPR029052 Metallo-dependent phosphatase-like AUP74_RS16450 0251a6fa5e7777ca62f732fd2d24cebd 270 Gene3D G3DSA:3.60.21.10 10 262 1.3E-38 T 11-11-2016 IPR029052 Metallo-dependent phosphatase-like AUP74_RS16450 0251a6fa5e7777ca62f732fd2d24cebd 270 Pfam PF00149 Calcineurin-like phosphoesterase 17 237 1.4E-12 T 11-11-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 AUP74_RS02740 bda078904ec7eb9f90be8aac921bd5fc 284 Gene3D G3DSA:3.60.110.10 3 243 7.5E-56 T 11-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AUP74_RS02740 bda078904ec7eb9f90be8aac921bd5fc 284 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 141 161 - T 11-11-2016 IPR001110 Uncharacterised protein family UPF0012, conserved site AUP74_RS02740 bda078904ec7eb9f90be8aac921bd5fc 284 SUPERFAMILY SSF56317 6 243 3.66E-56 T 11-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AUP74_RS02740 bda078904ec7eb9f90be8aac921bd5fc 284 Pfam PF00795 Carbon-nitrogen hydrolase 11 241 5.8E-33 T 11-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AUP74_RS12755 ad66ed96e36cadfec8c938512702aa75 429 Pfam PF03781 Sulfatase-modifying factor enzyme 1 188 425 1.9E-34 T 11-11-2016 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 AUP74_RS12755 ad66ed96e36cadfec8c938512702aa75 429 Gene3D G3DSA:3.90.1580.10 179 427 6.5E-61 T 11-11-2016 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 AUP74_RS12755 ad66ed96e36cadfec8c938512702aa75 429 Pfam PF12867 DinB superfamily 20 151 2.1E-7 T 11-11-2016 IPR024775 DinB-like domain AUP74_RS12755 ad66ed96e36cadfec8c938512702aa75 429 SUPERFAMILY SSF56436 186 427 1.53E-68 T 11-11-2016 IPR016187 C-type lectin fold AUP74_RS12755 ad66ed96e36cadfec8c938512702aa75 429 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 17 425 1.7E-167 T 11-11-2016 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255 AUP74_RS04580 8c7eb141984f3432b84bcc69927831b7 384 Gene3D G3DSA:3.40.50.450 117 284 9.9E-16 T 11-11-2016 AUP74_RS04580 8c7eb141984f3432b84bcc69927831b7 384 Pfam PF02481 DNA recombination-mediator protein A 77 284 2.8E-77 T 11-11-2016 IPR003488 DNA recombination-mediator protein A GO:0009294 AUP74_RS04580 8c7eb141984f3432b84bcc69927831b7 384 Gene3D G3DSA:1.10.10.10 330 375 3.1E-4 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS04580 8c7eb141984f3432b84bcc69927831b7 384 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 81 293 5.0E-77 T 11-11-2016 IPR003488 DNA recombination-mediator protein A GO:0009294 AUP74_RS04580 8c7eb141984f3432b84bcc69927831b7 384 SUPERFAMILY SSF46785 326 383 3.3E-5 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS04580 8c7eb141984f3432b84bcc69927831b7 384 SUPERFAMILY SSF102405 86 293 2.44E-46 T 11-11-2016 AUP74_RS10960 c219123577a69d88b942f20406579673 1167 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1157 0.0 T 11-11-2016 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 AUP74_RS10960 c219123577a69d88b942f20406579673 1167 Gene3D G3DSA:3.40.50.300 661 684 7.3E-64 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS10960 c219123577a69d88b942f20406579673 1167 Gene3D G3DSA:3.40.50.300 1 187 7.3E-64 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS10960 c219123577a69d88b942f20406579673 1167 Gene3D G3DSA:3.40.50.300 1051 1163 7.3E-64 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS10960 c219123577a69d88b942f20406579673 1167 SMART SM00968 520 620 9.3E-12 T 11-11-2016 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 AUP74_RS10960 c219123577a69d88b942f20406579673 1167 PIRSF PIRSF005719 1 1167 2.4E-280 T 11-11-2016 IPR024704 Structural maintenance of chromosomes protein AUP74_RS10960 c219123577a69d88b942f20406579673 1167 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1151 2.9E-63 T 11-11-2016 IPR003395 RecF/RecN/SMC, N-terminal AUP74_RS10960 c219123577a69d88b942f20406579673 1167 Pfam PF06470 SMC proteins Flexible Hinge Domain 524 619 2.6E-7 T 11-11-2016 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 AUP74_RS10960 c219123577a69d88b942f20406579673 1167 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1160 23.278 T 11-11-2016 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 AUP74_RS10960 c219123577a69d88b942f20406579673 1167 SUPERFAMILY SSF52540 1057 1143 1.24E-49 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS10960 c219123577a69d88b942f20406579673 1167 SUPERFAMILY SSF52540 1 217 1.24E-49 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS10960 c219123577a69d88b942f20406579673 1167 SUPERFAMILY SSF75553 486 667 7.59E-13 T 11-11-2016 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 AUP74_RS07920 442ba3088ce16876b4b055551a91fd06 592 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 1 585 2.1E-252 T 11-11-2016 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 Reactome: R-HSA-379726 AUP74_RS07920 442ba3088ce16876b4b055551a91fd06 592 Gene3D G3DSA:3.30.1360.30 279 416 5.4E-45 T 11-11-2016 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 AUP74_RS07920 442ba3088ce16876b4b055551a91fd06 592 SUPERFAMILY SSF50249 1 105 2.67E-33 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS07920 442ba3088ce16876b4b055551a91fd06 592 Pfam PF00152 tRNA synthetases class II (D, K and N) 120 559 1.9E-109 T 11-11-2016 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS07920 442ba3088ce16876b4b055551a91fd06 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 192 204 3.9E-27 T 11-11-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS07920 442ba3088ce16876b4b055551a91fd06 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 519 533 3.9E-27 T 11-11-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS07920 442ba3088ce16876b4b055551a91fd06 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 475 491 3.9E-27 T 11-11-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS07920 442ba3088ce16876b4b055551a91fd06 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 209 222 3.9E-27 T 11-11-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS07920 442ba3088ce16876b4b055551a91fd06 592 Pfam PF02938 GAD domain 309 409 4.8E-28 T 11-11-2016 IPR029351 GAD domain Reactome: R-HSA-379726 AUP74_RS07920 442ba3088ce16876b4b055551a91fd06 592 Hamap MF_00044 Aspartate--tRNA(Asp) ligase [aspS]. 1 564 37.037 T 11-11-2016 AUP74_RS07920 442ba3088ce16876b4b055551a91fd06 592 Gene3D G3DSA:3.30.930.10 134 278 9.1E-114 T 11-11-2016 AUP74_RS07920 442ba3088ce16876b4b055551a91fd06 592 Gene3D G3DSA:3.30.930.10 417 585 9.1E-114 T 11-11-2016 AUP74_RS07920 442ba3088ce16876b4b055551a91fd06 592 Gene3D G3DSA:2.40.50.140 1 107 1.8E-39 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS07920 442ba3088ce16876b4b055551a91fd06 592 SUPERFAMILY SSF55261 291 422 2.05E-42 T 11-11-2016 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 AUP74_RS07920 442ba3088ce16876b4b055551a91fd06 592 Pfam PF01336 OB-fold nucleic acid binding domain 18 102 6.0E-19 T 11-11-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 AUP74_RS07920 442ba3088ce16876b4b055551a91fd06 592 SUPERFAMILY SSF55681 109 293 2.67E-108 T 11-11-2016 AUP74_RS07920 442ba3088ce16876b4b055551a91fd06 592 SUPERFAMILY SSF55681 427 585 2.67E-108 T 11-11-2016 AUP74_RS13125 a3bb6219caa8e3fa6d45486f7152bc5e 484 Gene3D G3DSA:3.40.309.10 259 448 1.9E-75 T 11-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 AUP74_RS13125 a3bb6219caa8e3fa6d45486f7152bc5e 484 SUPERFAMILY SSF53720 6 476 1.03E-171 T 11-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AUP74_RS13125 a3bb6219caa8e3fa6d45486f7152bc5e 484 TIGRFAM TIGR01804 BADH: betaine-aldehyde dehydrogenase 7 471 1.3E-206 T 11-11-2016 IPR011264 Betaine aldehyde dehydrogenase GO:0008802|GO:0019285|GO:0046872 KEGG: 00260+1.2.1.8|MetaCyc: PWY-3722|MetaCyc: PWY-7494 AUP74_RS13125 a3bb6219caa8e3fa6d45486f7152bc5e 484 Pfam PF00171 Aldehyde dehydrogenase family 13 473 1.2E-176 T 11-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 AUP74_RS13125 a3bb6219caa8e3fa6d45486f7152bc5e 484 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 273 284 - T 11-11-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 AUP74_RS13125 a3bb6219caa8e3fa6d45486f7152bc5e 484 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 245 252 - T 11-11-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 AUP74_RS13125 a3bb6219caa8e3fa6d45486f7152bc5e 484 Gene3D G3DSA:3.40.605.10 6 258 6.0E-97 T 11-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AUP74_RS04340 7735ef9dc551cd831d798aefd176b923 385 SUPERFAMILY SSF51230 3 85 3.53E-21 T 11-11-2016 IPR011053 Single hybrid motif AUP74_RS04340 7735ef9dc551cd831d798aefd176b923 385 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 184 383 2.3E-43 T 11-11-2016 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 AUP74_RS04340 7735ef9dc551cd831d798aefd176b923 385 Pfam PF00364 Biotin-requiring enzyme 4 73 9.7E-16 T 11-11-2016 IPR000089 Biotin/lipoyl attachment AUP74_RS04340 7735ef9dc551cd831d798aefd176b923 385 SUPERFAMILY SSF52777 185 383 3.6E-50 T 11-11-2016 AUP74_RS04340 7735ef9dc551cd831d798aefd176b923 385 Gene3D G3DSA:2.40.50.100 4 78 7.5E-20 T 11-11-2016 AUP74_RS04340 7735ef9dc551cd831d798aefd176b923 385 Gene3D G3DSA:3.30.559.10 177 384 3.3E-45 T 11-11-2016 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 AUP74_RS04650 0d3619c529fa2a8393dc202c876f0b76 279 SMART SM00421 202 259 3.2E-15 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS04650 0d3619c529fa2a8393dc202c876f0b76 279 Pfam PF00196 Bacterial regulatory proteins, luxR family 204 256 3.8E-16 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS04650 0d3619c529fa2a8393dc202c876f0b76 279 Gene3D G3DSA:1.10.10.10 204 260 2.8E-17 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS04650 0d3619c529fa2a8393dc202c876f0b76 279 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 205 219 3.5E-9 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS04650 0d3619c529fa2a8393dc202c876f0b76 279 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 219 235 3.5E-9 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS04650 0d3619c529fa2a8393dc202c876f0b76 279 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 235 247 3.5E-9 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS04650 0d3619c529fa2a8393dc202c876f0b76 279 SUPERFAMILY SSF46894 198 260 2.41E-16 T 11-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AUP74_RS03960 6e58989cd8cbf1a29c77e0b7425058e2 573 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 392 410 3.8E-69 T 11-11-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AUP74_RS03960 6e58989cd8cbf1a29c77e0b7425058e2 573 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 136 154 3.8E-69 T 11-11-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AUP74_RS03960 6e58989cd8cbf1a29c77e0b7425058e2 573 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 285 304 3.8E-69 T 11-11-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AUP74_RS03960 6e58989cd8cbf1a29c77e0b7425058e2 573 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 414 432 3.8E-69 T 11-11-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AUP74_RS03960 6e58989cd8cbf1a29c77e0b7425058e2 573 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 154 173 3.8E-69 T 11-11-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AUP74_RS03960 6e58989cd8cbf1a29c77e0b7425058e2 573 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 62 87 3.8E-69 T 11-11-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AUP74_RS03960 6e58989cd8cbf1a29c77e0b7425058e2 573 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 476 493 3.8E-69 T 11-11-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AUP74_RS03960 6e58989cd8cbf1a29c77e0b7425058e2 573 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 255 271 3.8E-69 T 11-11-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AUP74_RS03960 6e58989cd8cbf1a29c77e0b7425058e2 573 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 451 466 3.8E-69 T 11-11-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AUP74_RS03960 6e58989cd8cbf1a29c77e0b7425058e2 573 SUPERFAMILY SSF56235 33 572 1.8E-164 T 11-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal AUP74_RS03960 6e58989cd8cbf1a29c77e0b7425058e2 573 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 41 565 7.2E-123 T 11-11-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AUP74_RS03960 6e58989cd8cbf1a29c77e0b7425058e2 573 Pfam PF01019 Gamma-glutamyltranspeptidase 55 568 1.6E-155 T 11-11-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 AUP74_RS07970 dd43d855125d76fbf839be54ca37d7c3 477 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 165 448 3.6E-79 T 11-11-2016 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 AUP74_RS07970 dd43d855125d76fbf839be54ca37d7c3 477 SUPERFAMILY SSF56059 261 451 3.2E-43 T 11-11-2016 AUP74_RS07970 dd43d855125d76fbf839be54ca37d7c3 477 Gene3D G3DSA:2.40.70.10 4 134 5.4E-44 T 11-11-2016 IPR021109 Aspartic peptidase domain AUP74_RS07970 dd43d855125d76fbf839be54ca37d7c3 477 Pfam PF05618 Putative ATP-dependant zinc protease 6 138 9.7E-38 T 11-11-2016 AUP74_RS07970 dd43d855125d76fbf839be54ca37d7c3 477 Gene3D G3DSA:3.30.1490.20 266 336 3.4E-6 T 11-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 AUP74_RS07970 dd43d855125d76fbf839be54ca37d7c3 477 Pfam PF08443 RimK-like ATP-grasp domain 261 449 1.4E-60 T 11-11-2016 IPR013651 ATP-grasp fold, RimK-type AUP74_RS07970 dd43d855125d76fbf839be54ca37d7c3 477 Gene3D G3DSA:3.30.470.20 337 438 1.2E-33 T 11-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 AUP74_RS07970 dd43d855125d76fbf839be54ca37d7c3 477 Gene3D G3DSA:3.40.50.20 169 265 2.2E-14 T 11-11-2016 IPR016185 Pre-ATP-grasp domain AUP74_RS07970 dd43d855125d76fbf839be54ca37d7c3 477 SUPERFAMILY SSF50630 6 140 9.0E-45 T 11-11-2016 IPR021109 Aspartic peptidase domain AUP74_RS13625 4b82063142a2541b51a1274a00a4c631 531 Gene3D G3DSA:3.30.1120.10 391 491 2.5E-11 T 11-11-2016 AUP74_RS13625 4b82063142a2541b51a1274a00a4c631 531 SUPERFAMILY SSF53649 10 492 3.49E-104 T 11-11-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 AUP74_RS13625 4b82063142a2541b51a1274a00a4c631 531 Pfam PF14707 C-terminal region of aryl-sulfatase 386 493 1.2E-9 T 11-11-2016 AUP74_RS13625 4b82063142a2541b51a1274a00a4c631 531 Pfam PF00884 Sulfatase 14 357 1.2E-57 T 11-11-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 AUP74_RS13625 4b82063142a2541b51a1274a00a4c631 531 Gene3D G3DSA:3.40.720.10 12 383 3.9E-91 T 11-11-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 AUP74_RS14630 ed43c0c3d72fd020bc79863819adc9a3 455 SUPERFAMILY SSF103378 17 439 9.81E-98 T 11-11-2016 IPR005656 MmgE/PrpD GO:0016829 AUP74_RS14630 ed43c0c3d72fd020bc79863819adc9a3 455 Pfam PF03972 MmgE/PrpD family 18 415 1.9E-100 T 11-11-2016 IPR005656 MmgE/PrpD GO:0016829 AUP74_RS14630 ed43c0c3d72fd020bc79863819adc9a3 455 Gene3D G3DSA:3.30.1330.120 263 386 2.7E-25 T 11-11-2016 AUP74_RS05325 ad06949f6ae09751b69943c93a1e13ea 279 Gene3D G3DSA:3.40.50.150 1 277 2.0E-103 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS05325 ad06949f6ae09751b69943c93a1e13ea 279 SUPERFAMILY SSF53335 9 275 1.41E-84 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS05325 ad06949f6ae09751b69943c93a1e13ea 279 Hamap MF_00934 Ribosomal RNA large subunit methyltransferase J [rlmJ]. 2 265 38.362 T 11-11-2016 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 AUP74_RS05325 ad06949f6ae09751b69943c93a1e13ea 279 Pfam PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ 33 267 1.3E-78 T 11-11-2016 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 AUP74_RS03095 5864be8bed94b5cb6686db6f6254bfe5 558 PIRSF PIRSF001423 1 558 1.7E-297 T 11-11-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AUP74_RS03095 5864be8bed94b5cb6686db6f6254bfe5 558 Hamap MF_00577 Urocanate hydratase [hutU]. 6 557 50.134 T 11-11-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AUP74_RS03095 5864be8bed94b5cb6686db6f6254bfe5 558 SUPERFAMILY SSF111326 6 557 7.85E-264 T 11-11-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AUP74_RS03095 5864be8bed94b5cb6686db6f6254bfe5 558 TIGRFAM TIGR01228 hutU: urocanate hydratase 12 555 9.8E-298 T 11-11-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AUP74_RS03095 5864be8bed94b5cb6686db6f6254bfe5 558 Pfam PF01175 Urocanase 13 548 1.1E-263 T 11-11-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AUP74_RS03095 5864be8bed94b5cb6686db6f6254bfe5 558 Gene3D G3DSA:3.40.50.10730 143 350 9.6E-96 T 11-11-2016 AUP74_RS03095 5864be8bed94b5cb6686db6f6254bfe5 558 Gene3D G3DSA:3.40.1770.10 9 142 5.0E-162 T 11-11-2016 AUP74_RS03095 5864be8bed94b5cb6686db6f6254bfe5 558 Gene3D G3DSA:3.40.1770.10 361 557 5.0E-162 T 11-11-2016 AUP74_RS03095 5864be8bed94b5cb6686db6f6254bfe5 558 ProSitePatterns PS01233 Urocanase signature. 443 458 - T 11-11-2016 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AUP74_RS03585 11608661ed97594afcbb96e97ef31951 490 SUPERFAMILY SSF143437 1 175 2.79E-46 T 11-11-2016 AUP74_RS03585 11608661ed97594afcbb96e97ef31951 490 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 490 193.913 T 11-11-2016 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 AUP74_RS03585 11608661ed97594afcbb96e97ef31951 490 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 177 371 1.0E-66 T 11-11-2016 IPR020536 Thil, AANH domain GO:0004810 AUP74_RS03585 11608661ed97594afcbb96e97ef31951 490 Gene3D G3DSA:3.40.50.620 175 335 1.0E-34 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS03585 11608661ed97594afcbb96e97ef31951 490 SUPERFAMILY SSF52821 405 482 6.58E-10 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS03585 11608661ed97594afcbb96e97ef31951 490 SUPERFAMILY SSF52402 176 375 2.65E-42 T 11-11-2016 AUP74_RS03585 11608661ed97594afcbb96e97ef31951 490 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 5 371 5.7E-107 T 11-11-2016 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 AUP74_RS03585 11608661ed97594afcbb96e97ef31951 490 Gene3D G3DSA:3.40.250.10 405 481 4.2E-8 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS03585 11608661ed97594afcbb96e97ef31951 490 SMART SM00981 77 167 2.4E-21 T 11-11-2016 IPR004114 THUMP domain GO:0003723 AUP74_RS03585 11608661ed97594afcbb96e97ef31951 490 TIGRFAM TIGR04271 ThiI_C_thiazole: thiazole biosynthesis domain 385 483 6.0E-35 T 11-11-2016 IPR026340 Thiazole biosynthesis domain GO:0052837 AUP74_RS03585 11608661ed97594afcbb96e97ef31951 490 Pfam PF02926 THUMP domain 63 161 6.1E-18 T 11-11-2016 IPR004114 THUMP domain GO:0003723 AUP74_RS07155 7366c3a67484ff164e2180aaf1e2cbb7 198 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 9 31 1.5E-7 T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS07155 7366c3a67484ff164e2180aaf1e2cbb7 198 Pfam PF12019 Type II transport protein GspH 48 165 4.4E-9 T 11-11-2016 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 AUP74_RS07155 7366c3a67484ff164e2180aaf1e2cbb7 198 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 9 29 - T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS07155 7366c3a67484ff164e2180aaf1e2cbb7 198 Gene3D G3DSA:3.30.700.10 11 59 1.4E-5 T 11-11-2016 AUP74_RS07155 7366c3a67484ff164e2180aaf1e2cbb7 198 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 6 29 2.6E-7 T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS07155 7366c3a67484ff164e2180aaf1e2cbb7 198 SUPERFAMILY SSF54523 11 155 1.26E-15 T 11-11-2016 AUP74_RS06820 b945359e8f114af808c5ed654c016374 103 SMART SM01403 7 101 7.2E-55 T 11-11-2016 IPR027486 Ribosomal protein S10 domain AUP74_RS06820 b945359e8f114af808c5ed654c016374 103 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 8.7E-19 T 11-11-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06820 b945359e8f114af808c5ed654c016374 103 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 8.7E-19 T 11-11-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06820 b945359e8f114af808c5ed654c016374 103 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 8.7E-19 T 11-11-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06820 b945359e8f114af808c5ed654c016374 103 Gene3D G3DSA:3.30.70.600 4 102 1.3E-43 T 11-11-2016 IPR027486 Ribosomal protein S10 domain AUP74_RS06820 b945359e8f114af808c5ed654c016374 103 Pfam PF00338 Ribosomal protein S10p/S20e 7 100 2.5E-35 T 11-11-2016 IPR027486 Ribosomal protein S10 domain AUP74_RS06820 b945359e8f114af808c5ed654c016374 103 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 26.858 T 11-11-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06820 b945359e8f114af808c5ed654c016374 103 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 11-11-2016 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06820 b945359e8f114af808c5ed654c016374 103 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 2.6E-46 T 11-11-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06820 b945359e8f114af808c5ed654c016374 103 SUPERFAMILY SSF54999 5 101 1.44E-36 T 11-11-2016 IPR027486 Ribosomal protein S10 domain AUP74_RS05365 628c43068ff4513e0fa59664497c9ef8 154 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 2 148 31.119 T 11-11-2016 IPR003791 Protein of unknown function UPF0178 AUP74_RS05365 628c43068ff4513e0fa59664497c9ef8 154 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 18 146 2.7E-49 T 11-11-2016 IPR003791 Protein of unknown function UPF0178 AUP74_RS04245 c7b115fbbdee3d3c4743e206f7e518e1 429 Pfam PF02321 Outer membrane efflux protein 32 212 4.5E-12 T 11-11-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 AUP74_RS04245 c7b115fbbdee3d3c4743e206f7e518e1 429 Pfam PF02321 Outer membrane efflux protein 246 420 1.5E-17 T 11-11-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 AUP74_RS04245 c7b115fbbdee3d3c4743e206f7e518e1 429 SUPERFAMILY SSF56954 2 422 9.02E-52 T 11-11-2016 AUP74_RS04245 c7b115fbbdee3d3c4743e206f7e518e1 429 Gene3D G3DSA:1.20.1600.10 22 422 6.3E-39 T 11-11-2016 AUP74_RS13830 3f790cc332e5c89c2eddbada243165c6 310 SUPERFAMILY SSF82861 38 119 7.98E-5 T 11-11-2016 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 AUP74_RS13830 3f790cc332e5c89c2eddbada243165c6 310 Pfam PF00924 Mechanosensitive ion channel 78 278 1.6E-41 T 11-11-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 AUP74_RS13830 3f790cc332e5c89c2eddbada243165c6 310 Gene3D G3DSA:2.30.30.60 137 181 2.2E-11 T 11-11-2016 AUP74_RS13830 3f790cc332e5c89c2eddbada243165c6 310 Gene3D G3DSA:3.30.70.100 191 276 3.3E-18 T 11-11-2016 AUP74_RS13830 3f790cc332e5c89c2eddbada243165c6 310 SUPERFAMILY SSF82689 191 289 4.18E-24 T 11-11-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 AUP74_RS13830 3f790cc332e5c89c2eddbada243165c6 310 SUPERFAMILY SSF50182 121 182 4.58E-13 T 11-11-2016 IPR010920 LSM domain AUP74_RS04695 7902be11cff78b16a967749216889224 192 Gene3D G3DSA:2.60.370.10 55 185 3.5E-48 T 11-11-2016 IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS04695 7902be11cff78b16a967749216889224 192 Pfam PF04442 Cytochrome c oxidase assembly protein CtaG/Cox11 30 170 3.1E-49 T 11-11-2016 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 AUP74_RS04695 7902be11cff78b16a967749216889224 192 SUPERFAMILY SSF110111 55 173 1.57E-46 T 11-11-2016 IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS04695 7902be11cff78b16a967749216889224 192 PIRSF PIRSF005413 2 188 2.2E-60 T 11-11-2016 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 AUP74_RS01925 ecb07866949f171b97d6994e400906ca 460 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 289 453 5.4E-24 T 11-11-2016 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 AUP74_RS01925 ecb07866949f171b97d6994e400906ca 460 Hamap MF_01010 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD [rlmD]. 25 460 64.875 T 11-11-2016 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 AUP74_RS01925 ecb07866949f171b97d6994e400906ca 460 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 442 452 - T 11-11-2016 IPR030391 RNA methyltransferase TrmA, conserved site AUP74_RS01925 ecb07866949f171b97d6994e400906ca 460 Gene3D G3DSA:2.40.50.140 22 94 2.0E-23 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS01925 ecb07866949f171b97d6994e400906ca 460 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 35 452 2.9E-105 T 11-11-2016 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 AUP74_RS01925 ecb07866949f171b97d6994e400906ca 460 SUPERFAMILY SSF53335 83 459 9.09E-80 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS01925 ecb07866949f171b97d6994e400906ca 460 Gene3D G3DSA:3.40.50.150 280 458 1.4E-59 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS01925 ecb07866949f171b97d6994e400906ca 460 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 391 421 - T 11-11-2016 IPR030390 RNA methyltransferase TrmA, active site AUP74_RS01925 ecb07866949f171b97d6994e400906ca 460 SUPERFAMILY SSF50249 24 79 4.11E-11 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS08085 4447159993ee16ba1dcf7c6e3dba3a76 245 Pfam PF00121 Triosephosphate isomerase 5 242 8.6E-85 T 11-11-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS08085 4447159993ee16ba1dcf7c6e3dba3a76 245 SUPERFAMILY SSF51351 1 244 2.88E-88 T 11-11-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS08085 4447159993ee16ba1dcf7c6e3dba3a76 245 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 235 3.5E-66 T 11-11-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS08085 4447159993ee16ba1dcf7c6e3dba3a76 245 ProSitePatterns PS00171 Triosephosphate isomerase active site. 165 175 - T 11-11-2016 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS08085 4447159993ee16ba1dcf7c6e3dba3a76 245 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 245 40.424 T 11-11-2016 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS08085 4447159993ee16ba1dcf7c6e3dba3a76 245 Gene3D G3DSA:3.20.20.70 1 244 2.3E-98 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS02965 3b00af4bcb11c0f410354d962a499026 176 SUPERFAMILY SSF75169 53 176 9.42E-21 T 11-11-2016 IPR027396 DsrEFH-like AUP74_RS02965 3b00af4bcb11c0f410354d962a499026 176 Pfam PF02635 DsrE/DsrF-like family 58 173 8.9E-15 T 11-11-2016 IPR003787 Sulphur relay, DsrE/F-like protein AUP74_RS02965 3b00af4bcb11c0f410354d962a499026 176 Gene3D G3DSA:3.40.1260.10 63 172 1.3E-11 T 11-11-2016 IPR027396 DsrEFH-like AUP74_RS09225 108b0cccb8c285a712b115a22fc7814e 823 Pfam PF07715 TonB-dependent Receptor Plug Domain 47 168 9.8E-19 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS09225 108b0cccb8c285a712b115a22fc7814e 823 SUPERFAMILY SSF56935 32 305 9.94E-86 T 11-11-2016 AUP74_RS09225 108b0cccb8c285a712b115a22fc7814e 823 SUPERFAMILY SSF56935 350 823 9.94E-86 T 11-11-2016 AUP74_RS09225 108b0cccb8c285a712b115a22fc7814e 823 Pfam PF00593 TonB dependent receptor 529 794 5.6E-19 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS09225 108b0cccb8c285a712b115a22fc7814e 823 Gene3D G3DSA:2.40.170.20 345 823 1.4E-68 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS09225 108b0cccb8c285a712b115a22fc7814e 823 Gene3D G3DSA:2.40.170.20 172 306 1.4E-68 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS09225 108b0cccb8c285a712b115a22fc7814e 823 Gene3D G3DSA:2.170.130.10 46 171 2.0E-29 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS02400 0a438649d0799e1b3163d465fb80f1de 128 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 49 78 - T 11-11-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 AUP74_RS02400 0a438649d0799e1b3163d465fb80f1de 128 Gene3D G3DSA:2.40.50.100 7 126 5.0E-52 T 11-11-2016 AUP74_RS02400 0a438649d0799e1b3163d465fb80f1de 128 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 5 127 31.295 T 11-11-2016 IPR002930 Glycine cleavage system H-protein AUP74_RS02400 0a438649d0799e1b3163d465fb80f1de 128 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 6 127 6.9E-52 T 11-11-2016 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 AUP74_RS02400 0a438649d0799e1b3163d465fb80f1de 128 Pfam PF01597 Glycine cleavage H-protein 8 127 3.6E-47 T 11-11-2016 IPR002930 Glycine cleavage system H-protein AUP74_RS02400 0a438649d0799e1b3163d465fb80f1de 128 SUPERFAMILY SSF51230 5 127 1.83E-45 T 11-11-2016 IPR011053 Single hybrid motif AUP74_RS10505 da331924e173bbcb0f7ce1af6ee2fc65 279 Gene3D G3DSA:3.40.50.150 46 235 1.9E-14 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS10505 da331924e173bbcb0f7ce1af6ee2fc65 279 SUPERFAMILY SSF53335 55 240 1.74E-16 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS10505 da331924e173bbcb0f7ce1af6ee2fc65 279 PIRSF PIRSF031679 2 273 2.3E-108 T 11-11-2016 IPR016980 S-adenosyl-L-methionine dependent methyltransferase, Alr7345, predicted AUP74_RS10505 da331924e173bbcb0f7ce1af6ee2fc65 279 Pfam PF13489 Methyltransferase domain 47 221 3.7E-10 T 11-11-2016 AUP74_RS06490 dbe93d6e60e139f118c15e6a8395a324 523 Gene3D G3DSA:3.40.50.1380 6 190 2.1E-85 T 11-11-2016 IPR011607 Methylglyoxal synthase-like domain AUP74_RS06490 dbe93d6e60e139f118c15e6a8395a324 523 SUPERFAMILY SSF52335 7 196 4.06E-71 T 11-11-2016 IPR011607 Methylglyoxal synthase-like domain AUP74_RS06490 dbe93d6e60e139f118c15e6a8395a324 523 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 8 523 6.8E-249 T 11-11-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AUP74_RS06490 dbe93d6e60e139f118c15e6a8395a324 523 Pfam PF01808 AICARFT/IMPCHase bienzyme 137 454 1.1E-117 T 11-11-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AUP74_RS06490 dbe93d6e60e139f118c15e6a8395a324 523 SMART SM00851 19 132 7.6E-62 T 11-11-2016 IPR011607 Methylglyoxal synthase-like domain AUP74_RS06490 dbe93d6e60e139f118c15e6a8395a324 523 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 7 523 45.874 T 11-11-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AUP74_RS06490 dbe93d6e60e139f118c15e6a8395a324 523 Pfam PF02142 MGS-like domain 19 132 7.9E-30 T 11-11-2016 IPR011607 Methylglyoxal synthase-like domain AUP74_RS06490 dbe93d6e60e139f118c15e6a8395a324 523 Gene3D G3DSA:3.40.140.20 371 513 1.6E-60 T 11-11-2016 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AUP74_RS06490 dbe93d6e60e139f118c15e6a8395a324 523 SUPERFAMILY SSF53927 214 523 7.22E-130 T 11-11-2016 IPR016193 Cytidine deaminase-like GO:0003824 AUP74_RS06490 dbe93d6e60e139f118c15e6a8395a324 523 PIRSF PIRSF000414 1 523 1.7E-224 T 11-11-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AUP74_RS06490 dbe93d6e60e139f118c15e6a8395a324 523 Gene3D G3DSA:3.40.140.20 246 365 2.5E-47 T 11-11-2016 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AUP74_RS06490 dbe93d6e60e139f118c15e6a8395a324 523 SMART SM00798 137 455 1.0E-211 T 11-11-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AUP74_RS15000 3576bf5e60c3be60944440410f918915 146 Gene3D G3DSA:3.10.180.10 3 131 3.0E-39 T 11-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AUP74_RS15000 3576bf5e60c3be60944440410f918915 146 SUPERFAMILY SSF54593 3 130 3.36E-32 T 11-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AUP74_RS15000 3576bf5e60c3be60944440410f918915 146 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 124 2.0E-15 T 11-11-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AUP74_RS10015 9048f22fe05c98bd50c029cfdd1059ec 484 Pfam PF06029 AlkA N-terminal domain 199 315 2.5E-35 T 11-11-2016 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal AUP74_RS10015 9048f22fe05c98bd50c029cfdd1059ec 484 Gene3D G3DSA:1.10.1670.10 432 481 2.1E-17 T 11-11-2016 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 AUP74_RS10015 9048f22fe05c98bd50c029cfdd1059ec 484 Gene3D G3DSA:3.40.10.10 3 84 1.5E-34 T 11-11-2016 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 AUP74_RS10015 9048f22fe05c98bd50c029cfdd1059ec 484 Gene3D G3DSA:1.10.10.60 85 136 3.1E-10 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS10015 9048f22fe05c98bd50c029cfdd1059ec 484 SUPERFAMILY SSF57884 2 86 3.53E-33 T 11-11-2016 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 AUP74_RS10015 9048f22fe05c98bd50c029cfdd1059ec 484 SUPERFAMILY SSF48150 305 479 3.14E-38 T 11-11-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AUP74_RS10015 9048f22fe05c98bd50c029cfdd1059ec 484 Pfam PF12833 Helix-turn-helix domain 105 183 2.5E-21 T 11-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AUP74_RS10015 9048f22fe05c98bd50c029cfdd1059ec 484 Pfam PF02805 Metal binding domain of Ada 8 71 6.0E-29 T 11-11-2016 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 AUP74_RS10015 9048f22fe05c98bd50c029cfdd1059ec 484 Gene3D G3DSA:3.30.310.20 199 315 8.2E-34 T 11-11-2016 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal AUP74_RS10015 9048f22fe05c98bd50c029cfdd1059ec 484 SUPERFAMILY SSF46689 136 184 2.02E-10 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS10015 9048f22fe05c98bd50c029cfdd1059ec 484 Gene3D G3DSA:1.10.10.60 139 184 1.4E-13 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS10015 9048f22fe05c98bd50c029cfdd1059ec 484 SMART SM01009 196 315 4.9E-45 T 11-11-2016 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal AUP74_RS10015 9048f22fe05c98bd50c029cfdd1059ec 484 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 322 466 7.5E-8 T 11-11-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AUP74_RS10015 9048f22fe05c98bd50c029cfdd1059ec 484 SMART SM00478 325 481 2.9E-15 T 11-11-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AUP74_RS10015 9048f22fe05c98bd50c029cfdd1059ec 484 Gene3D G3DSA:1.10.340.30 316 430 1.1E-28 T 11-11-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AUP74_RS10015 9048f22fe05c98bd50c029cfdd1059ec 484 SMART SM00342 99 182 5.1E-21 T 11-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AUP74_RS10015 9048f22fe05c98bd50c029cfdd1059ec 484 SUPERFAMILY SSF55945 199 296 2.35E-25 T 11-11-2016 AUP74_RS03835 28dc4a8ea5454edc2e9a3b6fbff5e88d 194 Pfam PF05036 Sporulation related domain 118 183 1.4E-15 T 11-11-2016 IPR007730 Sporulation-related domain GO:0042834 AUP74_RS03835 28dc4a8ea5454edc2e9a3b6fbff5e88d 194 SUPERFAMILY SSF110997 117 185 3.92E-16 T 11-11-2016 IPR007730 Sporulation-related domain GO:0042834 AUP74_RS03835 28dc4a8ea5454edc2e9a3b6fbff5e88d 194 Gene3D G3DSA:3.30.70.1070 118 189 3.2E-19 T 11-11-2016 IPR007730 Sporulation-related domain GO:0042834 AUP74_RS16660 5087f03b3317c784ea7064113442c57b 178 Pfam PF13633 Prokaryotic N-terminal methylation site 4 30 2.7E-12 T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS16660 5087f03b3317c784ea7064113442c57b 178 SUPERFAMILY SSF54523 7 130 4.08E-23 T 11-11-2016 AUP74_RS16660 5087f03b3317c784ea7064113442c57b 178 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 5 25 - T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS16660 5087f03b3317c784ea7064113442c57b 178 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 27 3.7E-10 T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS16660 5087f03b3317c784ea7064113442c57b 178 Pfam PF00114 Pilin (bacterial filament) 35 178 3.3E-14 T 11-11-2016 IPR001082 Fimbrial protein pilin GO:0007155|GO:0009289 AUP74_RS16660 5087f03b3317c784ea7064113442c57b 178 Gene3D G3DSA:3.30.700.10 7 178 2.1E-41 T 11-11-2016 AUP74_RS13505 161ec80e93af920d4f2a1ba1b198cf12 535 Gene3D G3DSA:3.90.226.10 271 524 1.3E-70 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS13505 161ec80e93af920d4f2a1ba1b198cf12 535 Gene3D G3DSA:3.90.226.10 32 270 1.1E-51 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS13505 161ec80e93af920d4f2a1ba1b198cf12 535 SUPERFAMILY SSF52096 39 268 1.34E-56 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS13505 161ec80e93af920d4f2a1ba1b198cf12 535 Pfam PF01039 Carboxyl transferase domain 48 519 1.3E-112 T 11-11-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AUP74_RS13505 161ec80e93af920d4f2a1ba1b198cf12 535 SUPERFAMILY SSF52096 270 533 4.13E-73 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS09790 37da9ec16a4893ad154a4ffd4f43b825 281 SUPERFAMILY SSF55620 150 277 6.12E-27 T 11-11-2016 AUP74_RS09790 37da9ec16a4893ad154a4ffd4f43b825 281 Gene3D G3DSA:3.30.479.10 15 131 4.2E-22 T 11-11-2016 AUP74_RS09790 37da9ec16a4893ad154a4ffd4f43b825 281 Gene3D G3DSA:3.30.479.10 151 277 1.6E-20 T 11-11-2016 AUP74_RS09790 37da9ec16a4893ad154a4ffd4f43b825 281 SUPERFAMILY SSF55620 1 154 5.45E-22 T 11-11-2016 AUP74_RS09790 37da9ec16a4893ad154a4ffd4f43b825 281 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 24 78 6.4E-7 T 11-11-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 AUP74_RS08650 80ca6c5b10a791090076a43d620f9411 127 SUPERFAMILY SSF52091 5 119 1.84E-21 T 11-11-2016 IPR002645 STAS domain AUP74_RS08650 80ca6c5b10a791090076a43d620f9411 127 Pfam PF11964 SpoIIAA-like 12 119 8.1E-16 T 11-11-2016 IPR021866 SpoIIAA-like AUP74_RS08650 80ca6c5b10a791090076a43d620f9411 127 Gene3D G3DSA:3.40.50.10600 2 119 1.1E-17 T 11-11-2016 IPR021866 SpoIIAA-like AUP74_RS07355 64d943926648a6459e6a3ee0e50add78 215 Pfam PF01553 Acyltransferase 46 157 1.7E-9 T 11-11-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 AUP74_RS07355 64d943926648a6459e6a3ee0e50add78 215 SMART SM00563 52 164 4.3E-12 T 11-11-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 AUP74_RS07355 64d943926648a6459e6a3ee0e50add78 215 SUPERFAMILY SSF69593 33 164 8.24E-16 T 11-11-2016 AUP74_RS09445 87c7e6f7fd4a625a1cefdf7877dc6040 342 Pfam PF01979 Amidohydrolase family 11 304 1.2E-11 T 11-11-2016 IPR006680 Amidohydrolase-related GO:0016787 AUP74_RS09445 87c7e6f7fd4a625a1cefdf7877dc6040 342 PIRSF PIRSF001237 1 342 1.5E-137 T 11-11-2016 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 AUP74_RS09445 87c7e6f7fd4a625a1cefdf7877dc6040 342 ProSitePatterns PS00483 Dihydroorotase signature 2. 244 255 - T 11-11-2016 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 AUP74_RS09445 87c7e6f7fd4a625a1cefdf7877dc6040 342 Gene3D G3DSA:3.20.20.140 2 341 1.7E-129 T 11-11-2016 AUP74_RS09445 87c7e6f7fd4a625a1cefdf7877dc6040 342 TIGRFAM TIGR00856 pyrC_dimer: dihydroorotase, homodimeric type 3 341 3.7E-134 T 11-11-2016 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 AUP74_RS09445 87c7e6f7fd4a625a1cefdf7877dc6040 342 Hamap MF_00219 Dihydroorotase [pyrC]. 2 342 43.214 T 11-11-2016 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 AUP74_RS09445 87c7e6f7fd4a625a1cefdf7877dc6040 342 ProSitePatterns PS00482 Dihydroorotase signature 1. 11 19 - T 11-11-2016 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 AUP74_RS09445 87c7e6f7fd4a625a1cefdf7877dc6040 342 SUPERFAMILY SSF51556 1 341 1.28E-141 T 11-11-2016 IPR032466 Metal-dependent hydrolase AUP74_RS07215 e2d5db528e9b4fa5af9570f6516d6723 578 Gene3D G3DSA:3.40.50.970 356 560 8.6E-73 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS07215 e2d5db528e9b4fa5af9570f6516d6723 578 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 166 4.9E-59 T 11-11-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 AUP74_RS07215 e2d5db528e9b4fa5af9570f6516d6723 578 Gene3D G3DSA:3.40.50.970 4 174 1.6E-74 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS07215 e2d5db528e9b4fa5af9570f6516d6723 578 SUPERFAMILY SSF52518 4 180 9.09E-65 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS07215 e2d5db528e9b4fa5af9570f6516d6723 578 SUPERFAMILY SSF52467 190 361 2.76E-63 T 11-11-2016 IPR029035 DHS-like NAD/FAD-binding domain AUP74_RS07215 e2d5db528e9b4fa5af9570f6516d6723 578 SUPERFAMILY SSF52518 377 562 2.75E-66 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS07215 e2d5db528e9b4fa5af9570f6516d6723 578 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 4 573 9.3E-254 T 11-11-2016 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 AUP74_RS07215 e2d5db528e9b4fa5af9570f6516d6723 578 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 398 548 1.1E-48 T 11-11-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AUP74_RS07215 e2d5db528e9b4fa5af9570f6516d6723 578 Gene3D G3DSA:3.40.50.1220 190 355 7.0E-64 T 11-11-2016 IPR029035 DHS-like NAD/FAD-binding domain AUP74_RS07215 e2d5db528e9b4fa5af9570f6516d6723 578 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 196 328 3.1E-43 T 11-11-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 AUP74_RS12310 6914d473df921d89ba9fbfaf23914807 309 SUPERFAMILY SSF52467 187 308 1.05E-48 T 11-11-2016 IPR029035 DHS-like NAD/FAD-binding domain AUP74_RS12310 6914d473df921d89ba9fbfaf23914807 309 SMART SM00893 3 182 5.7E-55 T 11-11-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 AUP74_RS12310 6914d473df921d89ba9fbfaf23914807 309 SUPERFAMILY SSF52402 2 186 2.26E-59 T 11-11-2016 AUP74_RS12310 6914d473df921d89ba9fbfaf23914807 309 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 253 279 - T 11-11-2016 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 AUP74_RS12310 6914d473df921d89ba9fbfaf23914807 309 Pfam PF01012 Electron transfer flavoprotein domain 4 170 4.8E-42 T 11-11-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 AUP74_RS12310 6914d473df921d89ba9fbfaf23914807 309 Gene3D G3DSA:3.40.50.620 1 182 3.8E-66 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS12310 6914d473df921d89ba9fbfaf23914807 309 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 190 272 2.6E-37 T 11-11-2016 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 AUP74_RS12310 6914d473df921d89ba9fbfaf23914807 309 Gene3D G3DSA:3.40.50.1220 185 309 1.6E-61 T 11-11-2016 IPR029035 DHS-like NAD/FAD-binding domain AUP74_RS12310 6914d473df921d89ba9fbfaf23914807 309 PIRSF PIRSF000089 1 309 2.0E-106 T 11-11-2016 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 AUP74_RS12675 ad037378480e5e4b10de339340f6212b 389 Gene3D G3DSA:4.10.320.10 120 166 1.2E-15 T 11-11-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 AUP74_RS12675 ad037378480e5e4b10de339340f6212b 389 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 11-11-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 AUP74_RS12675 ad037378480e5e4b10de339340f6212b 389 Pfam PF00364 Biotin-requiring enzyme 3 75 5.6E-17 T 11-11-2016 IPR000089 Biotin/lipoyl attachment AUP74_RS12675 ad037378480e5e4b10de339340f6212b 389 SUPERFAMILY SSF51230 3 83 2.62E-21 T 11-11-2016 IPR011053 Single hybrid motif AUP74_RS12675 ad037378480e5e4b10de339340f6212b 389 Gene3D G3DSA:2.40.50.100 3 87 1.4E-23 T 11-11-2016 AUP74_RS12675 ad037378480e5e4b10de339340f6212b 389 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 172 389 7.7E-58 T 11-11-2016 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 AUP74_RS12675 ad037378480e5e4b10de339340f6212b 389 Pfam PF02817 e3 binding domain 123 157 8.5E-12 T 11-11-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 AUP74_RS12675 ad037378480e5e4b10de339340f6212b 389 SUPERFAMILY SSF47005 120 161 6.54E-10 T 11-11-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 AUP74_RS12675 ad037378480e5e4b10de339340f6212b 389 SUPERFAMILY SSF52777 171 388 2.27E-55 T 11-11-2016 AUP74_RS12675 ad037378480e5e4b10de339340f6212b 389 Gene3D G3DSA:3.30.559.10 171 389 2.2E-54 T 11-11-2016 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 AUP74_RS13760 13711e46638ecddd10da3d4b7c2bd71c 1153 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 745 928 4.3E-18 T 11-11-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 AUP74_RS13760 13711e46638ecddd10da3d4b7c2bd71c 1153 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 469 554 1.3E-5 T 11-11-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AUP74_RS13760 13711e46638ecddd10da3d4b7c2bd71c 1153 Gene3D G3DSA:3.40.50.970 507 657 2.3E-7 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS13760 13711e46638ecddd10da3d4b7c2bd71c 1153 SUPERFAMILY SSF52518 28 248 5.71E-9 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS13760 13711e46638ecddd10da3d4b7c2bd71c 1153 SUPERFAMILY SSF53323 737 933 8.76E-18 T 11-11-2016 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 AUP74_RS13760 13711e46638ecddd10da3d4b7c2bd71c 1153 Gene3D G3DSA:3.40.920.10 738 929 1.3E-10 T 11-11-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 AUP74_RS13760 13711e46638ecddd10da3d4b7c2bd71c 1153 SUPERFAMILY SSF52518 448 634 7.3E-11 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS13760 13711e46638ecddd10da3d4b7c2bd71c 1153 SUPERFAMILY SSF52922 279 410 1.39E-7 T 11-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 AUP74_RS16380 e8a00be28e82243be90981848ac53a86 295 SUPERFAMILY SSF53474 48 294 1.13E-34 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS16380 e8a00be28e82243be90981848ac53a86 295 Pfam PF01738 Dienelactone hydrolase family 61 292 1.7E-33 T 11-11-2016 IPR002925 Dienelactone hydrolase GO:0016787 AUP74_RS16380 e8a00be28e82243be90981848ac53a86 295 Gene3D G3DSA:3.40.50.1820 46 292 1.5E-46 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS15170 15c98f905375eb9c49a18a9fb217eda5 443 Gene3D G3DSA:3.40.1660.10 5 63 3.7E-70 T 11-11-2016 AUP74_RS15170 15c98f905375eb9c49a18a9fb217eda5 443 Gene3D G3DSA:3.40.1660.10 283 424 3.7E-70 T 11-11-2016 AUP74_RS15170 15c98f905375eb9c49a18a9fb217eda5 443 SUPERFAMILY SSF159501 8 424 4.53E-120 T 11-11-2016 AUP74_RS15170 15c98f905375eb9c49a18a9fb217eda5 443 Gene3D G3DSA:3.30.1870.10 64 144 8.3E-26 T 11-11-2016 AUP74_RS15170 15c98f905375eb9c49a18a9fb217eda5 443 PIRSF PIRSF036794 2 430 3.3E-109 T 11-11-2016 IPR014622 Uncharacterised conserved protein UCP036794, erythromycin esterase-type AUP74_RS15170 15c98f905375eb9c49a18a9fb217eda5 443 Pfam PF05139 Erythromycin esterase 62 418 5.7E-106 T 11-11-2016 IPR007815 Erythromycin esterase GO:0046677 AUP74_RS05385 0635762a2b701aa48ca2900e35ec4a53 335 Gene3D G3DSA:3.40.50.1100 89 327 5.7E-65 T 11-11-2016 AUP74_RS05385 0635762a2b701aa48ca2900e35ec4a53 335 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 11 315 7.1E-52 T 11-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme AUP74_RS05385 0635762a2b701aa48ca2900e35ec4a53 335 PIRSF PIRSF006278 2 332 2.6E-92 T 11-11-2016 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase AUP74_RS05385 0635762a2b701aa48ca2900e35ec4a53 335 SUPERFAMILY SSF53686 6 326 4.53E-83 T 11-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme AUP74_RS13990 20da87e6ce2c94e1c2dd90aaf4ca0b99 364 SUPERFAMILY SSF54826 1 125 2.26E-28 T 11-11-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AUP74_RS13990 20da87e6ce2c94e1c2dd90aaf4ca0b99 364 Gene3D G3DSA:3.20.20.120 121 355 6.4E-70 T 11-11-2016 IPR029065 Enolase C-terminal domain-like AUP74_RS13990 20da87e6ce2c94e1c2dd90aaf4ca0b99 364 Gene3D G3DSA:3.30.390.10 1 120 2.0E-36 T 11-11-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AUP74_RS13990 20da87e6ce2c94e1c2dd90aaf4ca0b99 364 SMART SM00922 141 239 1.8E-22 T 11-11-2016 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal AUP74_RS13990 20da87e6ce2c94e1c2dd90aaf4ca0b99 364 SUPERFAMILY SSF51604 112 355 1.97E-64 T 11-11-2016 IPR029065 Enolase C-terminal domain-like AUP74_RS13990 20da87e6ce2c94e1c2dd90aaf4ca0b99 364 Pfam PF13378 Enolase C-terminal domain-like 144 355 9.2E-48 T 11-11-2016 IPR029065 Enolase C-terminal domain-like AUP74_RS13990 20da87e6ce2c94e1c2dd90aaf4ca0b99 364 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 13 124 2.0E-15 T 11-11-2016 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain AUP74_RS16295 a0bd4bccdd84af1fb2e4bcfecf3beef8 395 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 38 371 1.0E-62 T 11-11-2016 AUP74_RS16295 a0bd4bccdd84af1fb2e4bcfecf3beef8 395 SUPERFAMILY SSF48208 6 382 5.38E-78 T 11-11-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 AUP74_RS16295 a0bd4bccdd84af1fb2e4bcfecf3beef8 395 Gene3D G3DSA:1.50.10.10 4 377 4.2E-70 T 11-11-2016 IPR012341 Six-hairpin glycosidase GO:0003824 AUP74_RS04680 3b1cf4828a97a72548ecbb38c1e676f4 424 TIGRFAM TIGR00797 matE: MATE efflux family protein 1 396 1.4E-71 T 11-11-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AUP74_RS04680 3b1cf4828a97a72548ecbb38c1e676f4 424 Pfam PF01554 MatE 235 383 8.7E-9 T 11-11-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AUP74_RS04680 3b1cf4828a97a72548ecbb38c1e676f4 424 Pfam PF01554 MatE 1 155 2.5E-19 T 11-11-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AUP74_RS09035 2ea1a24d963f19905354cef37a29cdef 540 SUPERFAMILY SSF53697 10 536 5.84E-187 T 11-11-2016 AUP74_RS09035 2ea1a24d963f19905354cef37a29cdef 540 Gene3D G3DSA:3.40.50.10490 112 285 4.0E-69 T 11-11-2016 AUP74_RS09035 2ea1a24d963f19905354cef37a29cdef 540 Gene3D G3DSA:1.10.1390.10 503 539 3.0E-11 T 11-11-2016 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS09035 2ea1a24d963f19905354cef37a29cdef 540 PRINTS PR00662 Glucose-6-phosphate isomerase signature 334 355 1.2E-50 T 11-11-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS09035 2ea1a24d963f19905354cef37a29cdef 540 PRINTS PR00662 Glucose-6-phosphate isomerase signature 479 493 1.2E-50 T 11-11-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS09035 2ea1a24d963f19905354cef37a29cdef 540 PRINTS PR00662 Glucose-6-phosphate isomerase signature 493 506 1.2E-50 T 11-11-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS09035 2ea1a24d963f19905354cef37a29cdef 540 PRINTS PR00662 Glucose-6-phosphate isomerase signature 257 275 1.2E-50 T 11-11-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS09035 2ea1a24d963f19905354cef37a29cdef 540 PRINTS PR00662 Glucose-6-phosphate isomerase signature 461 479 1.2E-50 T 11-11-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS09035 2ea1a24d963f19905354cef37a29cdef 540 PRINTS PR00662 Glucose-6-phosphate isomerase signature 145 164 1.2E-50 T 11-11-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS09035 2ea1a24d963f19905354cef37a29cdef 540 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 261 274 - T 11-11-2016 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS09035 2ea1a24d963f19905354cef37a29cdef 540 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 493 510 - T 11-11-2016 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS09035 2ea1a24d963f19905354cef37a29cdef 540 Gene3D G3DSA:3.40.50.10490 13 98 5.4E-118 T 11-11-2016 AUP74_RS09035 2ea1a24d963f19905354cef37a29cdef 540 Gene3D G3DSA:3.40.50.10490 289 502 5.4E-118 T 11-11-2016 AUP74_RS09035 2ea1a24d963f19905354cef37a29cdef 540 Pfam PF00342 Phosphoglucose isomerase 52 535 5.6E-174 T 11-11-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS09035 2ea1a24d963f19905354cef37a29cdef 540 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 46 520 38.138 T 11-11-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS13005 dd89ac0fc9af473e269ae7d6a2c68037 158 SUPERFAMILY SSF52833 4 155 9.31E-50 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS13005 dd89ac0fc9af473e269ae7d6a2c68037 158 PIRSF PIRSF000239 1 155 4.4E-25 T 11-11-2016 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AUP74_RS13005 dd89ac0fc9af473e269ae7d6a2c68037 158 Gene3D G3DSA:3.40.30.10 3 155 2.9E-50 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS13005 dd89ac0fc9af473e269ae7d6a2c68037 158 Pfam PF00578 AhpC/TSA family 6 135 3.7E-38 T 11-11-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AUP74_RS00170 36683cd470e0ef32434132d6da10d66b 570 Pfam PF13432 Tetratricopeptide repeat 280 338 1.8E-5 T 11-11-2016 AUP74_RS00170 36683cd470e0ef32434132d6da10d66b 570 Pfam PF13432 Tetratricopeptide repeat 436 481 8.7E-4 T 11-11-2016 AUP74_RS00170 36683cd470e0ef32434132d6da10d66b 570 Pfam PF14559 Tetratricopeptide repeat 494 548 7.5E-7 T 11-11-2016 AUP74_RS00170 36683cd470e0ef32434132d6da10d66b 570 SMART SM00028 276 309 130.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS00170 36683cd470e0ef32434132d6da10d66b 570 SMART SM00028 175 208 81.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS00170 36683cd470e0ef32434132d6da10d66b 570 SMART SM00028 481 514 0.028 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS00170 36683cd470e0ef32434132d6da10d66b 570 SMART SM00028 108 141 120.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS00170 36683cd470e0ef32434132d6da10d66b 570 SMART SM00028 446 480 48.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS00170 36683cd470e0ef32434132d6da10d66b 570 SMART SM00028 515 547 230.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS00170 36683cd470e0ef32434132d6da10d66b 570 SUPERFAMILY SSF48452 380 548 3.34E-24 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS00170 36683cd470e0ef32434132d6da10d66b 570 SUPERFAMILY SSF48452 89 336 1.77E-14 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS00170 36683cd470e0ef32434132d6da10d66b 570 Gene3D G3DSA:1.25.40.10 255 548 1.5E-38 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS00170 36683cd470e0ef32434132d6da10d66b 570 Gene3D G3DSA:1.25.40.10 82 254 1.5E-10 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS06460 92e893014d3dd6a86f080fb4506b6425 349 Pfam PF02885 Glycosyl transferase family, helical bundle domain 5 64 4.0E-19 T 11-11-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 AUP74_RS06460 92e893014d3dd6a86f080fb4506b6425 349 Gene3D G3DSA:1.20.970.10 4 70 9.6E-28 T 11-11-2016 AUP74_RS06460 92e893014d3dd6a86f080fb4506b6425 349 Pfam PF00591 Glycosyl transferase family, a/b domain 74 328 1.4E-93 T 11-11-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AUP74_RS06460 92e893014d3dd6a86f080fb4506b6425 349 SUPERFAMILY SSF47648 3 69 8.11E-21 T 11-11-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 AUP74_RS06460 92e893014d3dd6a86f080fb4506b6425 349 Gene3D G3DSA:3.40.1030.10 74 340 1.3E-97 T 11-11-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AUP74_RS06460 92e893014d3dd6a86f080fb4506b6425 349 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 8 337 1.1E-120 T 11-11-2016 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 AUP74_RS06460 92e893014d3dd6a86f080fb4506b6425 349 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 5 338 38.055 T 11-11-2016 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 AUP74_RS06460 92e893014d3dd6a86f080fb4506b6425 349 SUPERFAMILY SSF52418 75 340 2.88E-85 T 11-11-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AUP74_RS14525 78ae4e16af4430341d10115adb58d6cd 480 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 276 287 - T 11-11-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 AUP74_RS14525 78ae4e16af4430341d10115adb58d6cd 480 Gene3D G3DSA:3.40.309.10 263 442 2.6E-59 T 11-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 AUP74_RS14525 78ae4e16af4430341d10115adb58d6cd 480 Gene3D G3DSA:3.40.605.10 3 262 2.7E-81 T 11-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AUP74_RS14525 78ae4e16af4430341d10115adb58d6cd 480 Pfam PF00171 Aldehyde dehydrogenase family 17 471 3.1E-149 T 11-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 AUP74_RS14525 78ae4e16af4430341d10115adb58d6cd 480 SUPERFAMILY SSF53720 3 476 3.4E-148 T 11-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AUP74_RS14525 78ae4e16af4430341d10115adb58d6cd 480 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 248 255 - T 11-11-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 AUP74_RS16250 f0978879741fbe9309ee07e4ff0b26e0 238 Pfam PF01936 NYN domain 7 142 1.3E-31 T 11-11-2016 IPR021139 NYN domain, limkain-b1-type AUP74_RS16250 f0978879741fbe9309ee07e4ff0b26e0 238 Gene3D G3DSA:3.40.50.1010 5 143 9.6E-27 T 11-11-2016 IPR029060 PIN domain-like AUP74_RS16250 f0978879741fbe9309ee07e4ff0b26e0 238 Pfam PF12872 OST-HTH/LOTUS domain 159 228 1.2E-14 T 11-11-2016 IPR025605 OST-HTH/LOTUS domain AUP74_RS13690 c086d5866d5ab2b8eec364c404b2edde 385 Gene3D G3DSA:1.10.540.10 1 119 1.8E-38 T 11-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 AUP74_RS13690 c086d5866d5ab2b8eec364c404b2edde 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 119 2.9E-31 T 11-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 AUP74_RS13690 c086d5866d5ab2b8eec364c404b2edde 385 Gene3D G3DSA:2.40.110.10 124 221 8.5E-43 T 11-11-2016 AUP74_RS13690 c086d5866d5ab2b8eec364c404b2edde 385 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 126 138 - T 11-11-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AUP74_RS13690 c086d5866d5ab2b8eec364c404b2edde 385 PIRSF PIRSF016578 3 384 1.5E-15 T 11-11-2016 AUP74_RS13690 c086d5866d5ab2b8eec364c404b2edde 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 220 1.2E-25 T 11-11-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 AUP74_RS13690 c086d5866d5ab2b8eec364c404b2edde 385 Gene3D G3DSA:1.20.140.10 222 382 4.9E-69 T 11-11-2016 AUP74_RS13690 c086d5866d5ab2b8eec364c404b2edde 385 SUPERFAMILY SSF56645 1 244 4.97E-82 T 11-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 AUP74_RS13690 c086d5866d5ab2b8eec364c404b2edde 385 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 339 358 - T 11-11-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AUP74_RS13690 c086d5866d5ab2b8eec364c404b2edde 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 232 381 1.6E-46 T 11-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AUP74_RS13690 c086d5866d5ab2b8eec364c404b2edde 385 SUPERFAMILY SSF47203 230 383 1.11E-55 T 11-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AUP74_RS15380 659b2298b416707fceea522976ca7d37 251 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 45 234 4.3E-50 T 11-11-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 AUP74_RS15380 659b2298b416707fceea522976ca7d37 251 ProSitePatterns PS00760 Signal peptidases I lysine active site. 126 138 - T 11-11-2016 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 AUP74_RS15380 659b2298b416707fceea522976ca7d37 251 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 124 136 4.6E-25 T 11-11-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 AUP74_RS15380 659b2298b416707fceea522976ca7d37 251 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 195 214 4.6E-25 T 11-11-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 AUP74_RS15380 659b2298b416707fceea522976ca7d37 251 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 60 76 4.6E-25 T 11-11-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 AUP74_RS15380 659b2298b416707fceea522976ca7d37 251 SUPERFAMILY SSF51306 58 241 9.68E-65 T 11-11-2016 IPR015927 Peptidase S24/S26A/S26B/S26C AUP74_RS15380 659b2298b416707fceea522976ca7d37 251 Pfam PF00717 Peptidase S24-like 66 148 7.1E-20 T 11-11-2016 IPR019759 Peptidase S24/S26A/S26B AUP74_RS15380 659b2298b416707fceea522976ca7d37 251 Pfam PF10502 Signal peptidase, peptidase S26 191 232 1.5E-5 T 11-11-2016 IPR019533 Peptidase S26 AUP74_RS15380 659b2298b416707fceea522976ca7d37 251 ProSitePatterns PS00761 Signal peptidases I signature 3. 200 213 - T 11-11-2016 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 AUP74_RS15380 659b2298b416707fceea522976ca7d37 251 Gene3D G3DSA:2.10.109.10 195 238 2.3E-53 T 11-11-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain AUP74_RS15380 659b2298b416707fceea522976ca7d37 251 Gene3D G3DSA:2.10.109.10 57 134 2.3E-53 T 11-11-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain AUP74_RS14720 b1f60f1004c83bc7bf10c009770cea5e 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 11-11-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS14720 b1f60f1004c83bc7bf10c009770cea5e 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.5E-38 T 11-11-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS14720 b1f60f1004c83bc7bf10c009770cea5e 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.5E-38 T 11-11-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS14720 b1f60f1004c83bc7bf10c009770cea5e 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.5E-38 T 11-11-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS14720 b1f60f1004c83bc7bf10c009770cea5e 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 70 1.0E-18 T 11-11-2016 AUP74_RS14720 b1f60f1004c83bc7bf10c009770cea5e 119 Pfam PF00453 Ribosomal protein L20 3 108 2.2E-47 T 11-11-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS14720 b1f60f1004c83bc7bf10c009770cea5e 119 Gene3D G3DSA:1.10.1900.20 55 117 2.2E-28 T 11-11-2016 AUP74_RS14720 b1f60f1004c83bc7bf10c009770cea5e 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 3.8E-49 T 11-11-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS14720 b1f60f1004c83bc7bf10c009770cea5e 119 SUPERFAMILY SSF74731 3 117 4.58E-48 T 11-11-2016 AUP74_RS14720 b1f60f1004c83bc7bf10c009770cea5e 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 30.332 T 11-11-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS02735 fab48d941b5145cfa1c40b24b5ab6cb4 792 Gene3D G3DSA:2.40.170.20 187 230 3.6E-65 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS02735 fab48d941b5145cfa1c40b24b5ab6cb4 792 Gene3D G3DSA:2.40.170.20 262 792 3.6E-65 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS02735 fab48d941b5145cfa1c40b24b5ab6cb4 792 Gene3D G3DSA:2.170.130.10 32 177 2.2E-30 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS02735 fab48d941b5145cfa1c40b24b5ab6cb4 792 SUPERFAMILY SSF56935 31 231 2.75E-98 T 11-11-2016 AUP74_RS02735 fab48d941b5145cfa1c40b24b5ab6cb4 792 SUPERFAMILY SSF56935 263 792 2.75E-98 T 11-11-2016 AUP74_RS02735 fab48d941b5145cfa1c40b24b5ab6cb4 792 Pfam PF07715 TonB-dependent Receptor Plug Domain 55 167 3.8E-14 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS16010 e787d4984dc3926ec0318dc36c13db2b 305 Pfam PF08282 haloacid dehalogenase-like hydrolase 24 89 3.5E-8 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS16010 e787d4984dc3926ec0318dc36c13db2b 305 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 23 253 1.4E-17 T 11-11-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 AUP74_RS16010 e787d4984dc3926ec0318dc36c13db2b 305 SUPERFAMILY SSF56784 22 257 1.26E-35 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS16010 e787d4984dc3926ec0318dc36c13db2b 305 TIGRFAM TIGR01486 HAD-SF-IIB-MPGP: mannosyl-3-phosphoglycerate phosphatase family 23 290 5.2E-64 T 11-11-2016 IPR006381 HAD-superfamily hydrolase, superfamily IIB, MPGP GO:0005737|GO:0050531|GO:0051479 KEGG: 00051+3.1.3.70|MetaCyc: PWY-5656 AUP74_RS16010 e787d4984dc3926ec0318dc36c13db2b 305 Gene3D G3DSA:3.30.980.20 118 202 1.1E-24 T 11-11-2016 AUP74_RS16010 e787d4984dc3926ec0318dc36c13db2b 305 Gene3D G3DSA:3.40.50.1000 22 102 6.8E-32 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS16010 e787d4984dc3926ec0318dc36c13db2b 305 Gene3D G3DSA:3.40.50.1000 203 287 6.8E-32 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS10745 25ccb8dca869fc1f56a3e7eefdd91c84 560 Pfam PF06826 Predicted Permease Membrane Region 391 556 4.9E-19 T 11-11-2016 IPR006512 YidE/YbjL duplication AUP74_RS10745 25ccb8dca869fc1f56a3e7eefdd91c84 560 Pfam PF06826 Predicted Permease Membrane Region 15 184 3.5E-25 T 11-11-2016 IPR006512 YidE/YbjL duplication AUP74_RS10745 25ccb8dca869fc1f56a3e7eefdd91c84 560 SUPERFAMILY SSF116726 293 377 5.89E-11 T 11-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AUP74_RS10745 25ccb8dca869fc1f56a3e7eefdd91c84 560 Pfam PF02080 TrkA-C domain 308 372 2.1E-8 T 11-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AUP74_RS10745 25ccb8dca869fc1f56a3e7eefdd91c84 560 Gene3D G3DSA:3.30.70.1450 307 379 3.3E-8 T 11-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AUP74_RS08105 4d8ab40ed7229e37dd28bc6610ffb5da 673 Gene3D G3DSA:1.25.40.10 179 295 2.2E-7 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS08105 4d8ab40ed7229e37dd28bc6610ffb5da 673 Gene3D G3DSA:1.25.40.10 118 178 9.7E-5 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS08105 4d8ab40ed7229e37dd28bc6610ffb5da 673 SUPERFAMILY SSF48452 105 194 1.07E-6 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS08105 4d8ab40ed7229e37dd28bc6610ffb5da 673 Pfam PF13432 Tetratricopeptide repeat 245 295 9.0E-8 T 11-11-2016 AUP74_RS08105 4d8ab40ed7229e37dd28bc6610ffb5da 673 SUPERFAMILY SSF48452 167 295 6.13E-10 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS02235 9c3e72d28108c16867849221cb5c5c64 433 Pfam PF04932 O-Antigen ligase 213 337 2.9E-6 T 11-11-2016 IPR007016 O-antigen ligase-related AUP74_RS14700 2c057cd5fb4fb1e06cce80a2b9ab2475 120 Gene3D G3DSA:1.10.1660.10 16 83 8.1E-16 T 11-11-2016 AUP74_RS14700 2c057cd5fb4fb1e06cce80a2b9ab2475 120 SMART SM00422 19 89 4.8E-5 T 11-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AUP74_RS14700 2c057cd5fb4fb1e06cce80a2b9ab2475 120 Pfam PF13411 MerR HTH family regulatory protein 19 86 2.2E-21 T 11-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AUP74_RS14700 2c057cd5fb4fb1e06cce80a2b9ab2475 120 SUPERFAMILY SSF46955 17 116 7.78E-18 T 11-11-2016 IPR009061 Putative DNA-binding domain AUP74_RS06075 baeecf703d32541922d37c842fa17bce 655 SUPERFAMILY SSF48371 510 644 4.03E-39 T 11-11-2016 IPR016024 Armadillo-type fold GO:0005488 AUP74_RS06075 baeecf703d32541922d37c842fa17bce 655 Pfam PF01433 Peptidase family M1 72 435 3.1E-71 T 11-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AUP74_RS06075 baeecf703d32541922d37c842fa17bce 655 Pfam PF09127 Leukotriene A4 hydrolase, C-terminal 527 643 6.8E-33 T 11-11-2016 IPR015211 Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal GO:0008237|GO:0008270 KEGG: 00590+3.3.2.6 AUP74_RS06075 baeecf703d32541922d37c842fa17bce 655 Gene3D G3DSA:1.10.390.10 356 503 6.6E-38 T 11-11-2016 AUP74_RS06075 baeecf703d32541922d37c842fa17bce 655 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 242 257 7.4E-18 T 11-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AUP74_RS06075 baeecf703d32541922d37c842fa17bce 655 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 316 326 7.4E-18 T 11-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AUP74_RS06075 baeecf703d32541922d37c842fa17bce 655 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 343 358 7.4E-18 T 11-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AUP74_RS06075 baeecf703d32541922d37c842fa17bce 655 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 197 212 7.4E-18 T 11-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AUP74_RS06075 baeecf703d32541922d37c842fa17bce 655 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 362 374 7.4E-18 T 11-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AUP74_RS06075 baeecf703d32541922d37c842fa17bce 655 SUPERFAMILY SSF55486 263 503 1.76E-68 T 11-11-2016 AUP74_RS06075 baeecf703d32541922d37c842fa17bce 655 SMART SM01263 511 649 1.4E-48 T 11-11-2016 IPR015211 Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal GO:0008237|GO:0008270 KEGG: 00590+3.3.2.6 AUP74_RS06075 baeecf703d32541922d37c842fa17bce 655 SUPERFAMILY SSF63737 60 259 1.16E-42 T 11-11-2016 AUP74_RS09265 870a1d24a850e25ba85dc97c43ae5d88 297 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 3 296 23.837 T 11-11-2016 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09265 870a1d24a850e25ba85dc97c43ae5d88 297 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 29 44 - T 11-11-2016 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09265 870a1d24a850e25ba85dc97c43ae5d88 297 Pfam PF00146 NADH dehydrogenase 2 289 2.4E-123 T 11-11-2016 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09265 870a1d24a850e25ba85dc97c43ae5d88 297 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 184 197 - T 11-11-2016 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS06880 591bb70ef7594d023235badb81eb2fb7 105 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 102 4.0E-25 T 11-11-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06880 591bb70ef7594d023235badb81eb2fb7 105 Pfam PF00467 KOW motif 7 32 1.9E-5 T 11-11-2016 IPR005824 KOW AUP74_RS06880 591bb70ef7594d023235badb81eb2fb7 105 SUPERFAMILY SSF50104 3 101 3.61E-31 T 11-11-2016 IPR008991 Translation protein SH3-like domain AUP74_RS06880 591bb70ef7594d023235badb81eb2fb7 105 ProSitePatterns PS01108 Ribosomal protein L24 signature. 7 24 - T 11-11-2016 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS06880 591bb70ef7594d023235badb81eb2fb7 105 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 2 97 18.751 T 11-11-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06880 591bb70ef7594d023235badb81eb2fb7 105 SMART SM00739 3 30 4.3E-4 T 11-11-2016 IPR005824 KOW AUP74_RS06880 591bb70ef7594d023235badb81eb2fb7 105 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 103 2.8E-36 T 11-11-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06880 591bb70ef7594d023235badb81eb2fb7 105 Gene3D G3DSA:2.30.30.30 3 91 2.3E-20 T 11-11-2016 IPR014722 Ribosomal protein L2 domain 2 AUP74_RS16005 b756604626bcbf76d16e934c1328014a 120 Pfam PF05433 Glycine zipper 2TM domain 1 39 3.3E-7 T 11-11-2016 IPR008816 Glycine zipper 2TM domain GO:0019867 AUP74_RS16005 b756604626bcbf76d16e934c1328014a 120 PIRSF PIRSF002721 1 119 1.0E-30 T 11-11-2016 IPR016364 Surface antigen, Rickettsia type AUP74_RS16445 93c5f41997d447e54fc8e92c36f05663 452 SUPERFAMILY SSF51735 210 447 1.17E-63 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS16445 93c5f41997d447e54fc8e92c36f05663 452 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 219 446 2.5E-51 T 11-11-2016 AUP74_RS16445 93c5f41997d447e54fc8e92c36f05663 452 SUPERFAMILY SSF51735 139 195 5.12E-5 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS16445 93c5f41997d447e54fc8e92c36f05663 452 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 358 377 4.8E-34 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS16445 93c5f41997d447e54fc8e92c36f05663 452 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 379 396 4.8E-34 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS16445 93c5f41997d447e54fc8e92c36f05663 452 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 332 348 4.8E-34 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS16445 93c5f41997d447e54fc8e92c36f05663 452 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 412 432 4.8E-34 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS16445 93c5f41997d447e54fc8e92c36f05663 452 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 285 296 4.8E-34 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS16445 93c5f41997d447e54fc8e92c36f05663 452 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 231 4.8E-34 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS16445 93c5f41997d447e54fc8e92c36f05663 452 Gene3D G3DSA:3.40.50.720 203 447 6.3E-69 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS16445 93c5f41997d447e54fc8e92c36f05663 452 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 358 377 2.7E-7 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS16445 93c5f41997d447e54fc8e92c36f05663 452 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 285 296 2.7E-7 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS16445 93c5f41997d447e54fc8e92c36f05663 452 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 338 346 2.7E-7 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS16445 93c5f41997d447e54fc8e92c36f05663 452 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 213 389 1.4E-6 T 11-11-2016 AUP74_RS16445 93c5f41997d447e54fc8e92c36f05663 452 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 345 373 - T 11-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AUP74_RS09595 a08805d92aa99adefe6a277ae69a0c13 350 Pfam PF00589 Phage integrase family 117 313 8.5E-43 T 11-11-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AUP74_RS09595 a08805d92aa99adefe6a277ae69a0c13 350 TIGRFAM TIGR02249 integrase_gron: integron integrase 15 328 2.0E-126 T 11-11-2016 IPR011946 Integrase, integron-type GO:0003677|GO:0006310|GO:0015074 AUP74_RS09595 a08805d92aa99adefe6a277ae69a0c13 350 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 15 97 7.8E-24 T 11-11-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 AUP74_RS09595 a08805d92aa99adefe6a277ae69a0c13 350 SUPERFAMILY SSF56349 16 314 5.0E-46 T 11-11-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AUP74_RS09595 a08805d92aa99adefe6a277ae69a0c13 350 Gene3D G3DSA:1.10.443.10 114 315 4.0E-46 T 11-11-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 AUP74_RS13040 8fbf4397dc66af47f1a3aa08db0ff286 209 SUPERFAMILY SSF52540 1 208 4.88E-53 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS13040 8fbf4397dc66af47f1a3aa08db0ff286 209 Hamap MF_00165 Thymidylate kinase [tmk]. 5 206 30.117 T 11-11-2016 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 AUP74_RS13040 8fbf4397dc66af47f1a3aa08db0ff286 209 Pfam PF02223 Thymidylate kinase 9 197 6.3E-49 T 11-11-2016 AUP74_RS13040 8fbf4397dc66af47f1a3aa08db0ff286 209 Gene3D G3DSA:3.40.50.300 3 207 8.1E-69 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS13040 8fbf4397dc66af47f1a3aa08db0ff286 209 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 1 197 4.0E-52 T 11-11-2016 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 AUP74_RS08505 b26a317baef0db3d9070954b7f3c8e97 272 Pfam PF04397 LytTr DNA-binding domain 168 263 1.1E-22 T 11-11-2016 IPR007492 LytTR DNA-binding domain GO:0003677 AUP74_RS08505 b26a317baef0db3d9070954b7f3c8e97 272 SMART SM00850 167 264 1.6E-32 T 11-11-2016 IPR007492 LytTR DNA-binding domain GO:0003677 AUP74_RS08505 b26a317baef0db3d9070954b7f3c8e97 272 Gene3D G3DSA:2.40.50.40 160 227 1.8E-17 T 11-11-2016 AUP74_RS08505 b26a317baef0db3d9070954b7f3c8e97 272 Gene3D G3DSA:3.40.50.2300 2 120 6.1E-33 T 11-11-2016 AUP74_RS08505 b26a317baef0db3d9070954b7f3c8e97 272 SUPERFAMILY SSF52172 1 123 7.12E-35 T 11-11-2016 IPR011006 CheY-like superfamily AUP74_RS08505 b26a317baef0db3d9070954b7f3c8e97 272 Pfam PF00072 Response regulator receiver domain 7 114 1.5E-25 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS08505 b26a317baef0db3d9070954b7f3c8e97 272 SMART SM00448 4 114 7.5E-31 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS08785 450c645c5e2e339477ddd033bd69e755 753 Gene3D G3DSA:3.40.50.300 536 716 5.1E-34 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS08785 450c645c5e2e339477ddd033bd69e755 753 Pfam PF13807 G-rich domain on putative tyrosine kinase 394 465 5.2E-16 T 11-11-2016 IPR032807 Tyrosine kinase, G-rich domain AUP74_RS08785 450c645c5e2e339477ddd033bd69e755 753 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 517 719 1.6E-48 T 11-11-2016 IPR005702 Exopolysaccharide synthesis protein GO:0045226 AUP74_RS08785 450c645c5e2e339477ddd033bd69e755 753 Pfam PF13614 AAA domain 536 679 9.3E-12 T 11-11-2016 IPR025669 AAA domain AUP74_RS08785 450c645c5e2e339477ddd033bd69e755 753 SUPERFAMILY SSF52540 535 723 1.15E-38 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS08785 450c645c5e2e339477ddd033bd69e755 753 Pfam PF02706 Chain length determinant protein 19 196 6.8E-23 T 11-11-2016 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 AUP74_RS13215 92a9524168bb1f8e69b52060634167ea 1146 Gene3D G3DSA:3.40.50.300 493 603 1.3E-38 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS13215 92a9524168bb1f8e69b52060634167ea 1146 Gene3D G3DSA:3.40.50.300 767 892 1.3E-38 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS13215 92a9524168bb1f8e69b52060634167ea 1146 Pfam PF13361 UvrD-like helicase C-terminal domain 491 867 1.7E-23 T 11-11-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 AUP74_RS13215 92a9524168bb1f8e69b52060634167ea 1146 Pfam PF00580 UvrD/REP helicase N-terminal domain 19 477 6.1E-41 T 11-11-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 AUP74_RS13215 92a9524168bb1f8e69b52060634167ea 1146 Gene3D G3DSA:1.10.486.10 612 717 1.8E-6 T 11-11-2016 AUP74_RS13215 92a9524168bb1f8e69b52060634167ea 1146 Gene3D G3DSA:3.40.50.300 374 478 3.0E-46 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS13215 92a9524168bb1f8e69b52060634167ea 1146 Gene3D G3DSA:3.40.50.300 13 71 3.0E-46 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS13215 92a9524168bb1f8e69b52060634167ea 1146 Gene3D G3DSA:3.40.50.300 119 183 3.0E-46 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS13215 92a9524168bb1f8e69b52060634167ea 1146 SUPERFAMILY SSF52540 111 195 2.13E-90 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS13215 92a9524168bb1f8e69b52060634167ea 1146 SUPERFAMILY SSF52540 19 75 2.13E-90 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS13215 92a9524168bb1f8e69b52060634167ea 1146 SUPERFAMILY SSF52540 364 812 2.13E-90 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS13215 92a9524168bb1f8e69b52060634167ea 1146 SUPERFAMILY SSF52540 849 875 2.13E-90 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS02340 66de8f4ba3d90c9cd6640845814e9fc3 170 PIRSF PIRSF000194 1 170 2.2E-65 T 11-11-2016 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 AUP74_RS02340 66de8f4ba3d90c9cd6640845814e9fc3 170 Gene3D G3DSA:3.40.430.10 4 169 2.7E-63 T 11-11-2016 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 AUP74_RS02340 66de8f4ba3d90c9cd6640845814e9fc3 170 PRINTS PR00070 Dihydrofolate reductase signature 17 27 5.6E-17 T 11-11-2016 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 AUP74_RS02340 66de8f4ba3d90c9cd6640845814e9fc3 170 PRINTS PR00070 Dihydrofolate reductase signature 44 55 5.6E-17 T 11-11-2016 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 AUP74_RS02340 66de8f4ba3d90c9cd6640845814e9fc3 170 PRINTS PR00070 Dihydrofolate reductase signature 101 115 5.6E-17 T 11-11-2016 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 AUP74_RS02340 66de8f4ba3d90c9cd6640845814e9fc3 170 PRINTS PR00070 Dihydrofolate reductase signature 31 39 5.6E-17 T 11-11-2016 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 AUP74_RS02340 66de8f4ba3d90c9cd6640845814e9fc3 170 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 17 39 - T 11-11-2016 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-113510|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-69205 AUP74_RS02340 66de8f4ba3d90c9cd6640845814e9fc3 170 Pfam PF00186 Dihydrofolate reductase 6 168 4.4E-60 T 11-11-2016 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 AUP74_RS02340 66de8f4ba3d90c9cd6640845814e9fc3 170 SUPERFAMILY SSF53597 5 168 9.69E-58 T 11-11-2016 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 AUP74_RS16185 f9f24f191e57e148e683b942e979c564 366 SUPERFAMILY SSF56601 11 346 2.48E-74 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS16185 f9f24f191e57e148e683b942e979c564 366 Pfam PF00144 Beta-lactamase 14 339 2.7E-60 T 11-11-2016 IPR001466 Beta-lactamase-related AUP74_RS16185 f9f24f191e57e148e683b942e979c564 366 Gene3D G3DSA:3.40.710.10 22 348 2.8E-72 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS01175 c8693a602419b92733812c589030f30a 191 SUPERFAMILY SSF54593 19 175 2.69E-32 T 11-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AUP74_RS01175 c8693a602419b92733812c589030f30a 191 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 26 140 4.4E-17 T 11-11-2016 AUP74_RS01175 c8693a602419b92733812c589030f30a 191 Gene3D G3DSA:3.10.180.10 20 169 2.0E-35 T 11-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AUP74_RS04420 3b0b4bd03595f0b21a479f40f46c2586 308 Hamap MF_01393 ATP synthase subunit a [atpB]. 12 301 14.984 T 11-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 AUP74_RS04420 3b0b4bd03595f0b21a479f40f46c2586 308 ProSitePatterns PS00449 ATP synthase a subunit signature. 231 240 - T 11-11-2016 IPR023011 ATPase, F0 complex, subunit A, active site Reactome: R-HSA-163210 AUP74_RS04420 3b0b4bd03595f0b21a479f40f46c2586 308 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 56 295 3.8E-44 T 11-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 AUP74_RS04420 3b0b4bd03595f0b21a479f40f46c2586 308 Gene3D G3DSA:1.20.120.220 113 300 1.1E-51 T 11-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 AUP74_RS04420 3b0b4bd03595f0b21a479f40f46c2586 308 SUPERFAMILY SSF81336 114 294 4.45E-40 T 11-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 AUP74_RS04420 3b0b4bd03595f0b21a479f40f46c2586 308 Pfam PF00119 ATP synthase A chain 65 294 1.9E-55 T 11-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 AUP74_RS09025 105b1378a9676e5c110b26fefcd9c8a3 253 SMART SM00244 19 176 6.0E-63 T 11-11-2016 IPR001107 Band 7 domain AUP74_RS09025 105b1378a9676e5c110b26fefcd9c8a3 253 Pfam PF01145 SPFH domain / Band 7 family 24 193 1.5E-35 T 11-11-2016 IPR001107 Band 7 domain AUP74_RS09025 105b1378a9676e5c110b26fefcd9c8a3 253 SUPERFAMILY SSF117892 50 183 7.59E-45 T 11-11-2016 IPR001107 Band 7 domain AUP74_RS09025 105b1378a9676e5c110b26fefcd9c8a3 253 PRINTS PR00721 Stomatin signature 73 94 3.3E-59 T 11-11-2016 IPR001972 Stomatin family GO:0016020 AUP74_RS09025 105b1378a9676e5c110b26fefcd9c8a3 253 PRINTS PR00721 Stomatin signature 128 151 3.3E-59 T 11-11-2016 IPR001972 Stomatin family GO:0016020 AUP74_RS09025 105b1378a9676e5c110b26fefcd9c8a3 253 PRINTS PR00721 Stomatin signature 152 170 3.3E-59 T 11-11-2016 IPR001972 Stomatin family GO:0016020 AUP74_RS09025 105b1378a9676e5c110b26fefcd9c8a3 253 PRINTS PR00721 Stomatin signature 26 48 3.3E-59 T 11-11-2016 IPR001972 Stomatin family GO:0016020 AUP74_RS09025 105b1378a9676e5c110b26fefcd9c8a3 253 PRINTS PR00721 Stomatin signature 171 192 3.3E-59 T 11-11-2016 IPR001972 Stomatin family GO:0016020 AUP74_RS09025 105b1378a9676e5c110b26fefcd9c8a3 253 PRINTS PR00721 Stomatin signature 108 125 3.3E-59 T 11-11-2016 IPR001972 Stomatin family GO:0016020 AUP74_RS09025 105b1378a9676e5c110b26fefcd9c8a3 253 PRINTS PR00721 Stomatin signature 196 219 3.3E-59 T 11-11-2016 IPR001972 Stomatin family GO:0016020 AUP74_RS05020 9e6bed8e4901d941226f34f327959d5e 396 Pfam PF04230 Polysaccharide pyruvyl transferase 6 326 1.4E-24 T 11-11-2016 IPR007345 Polysaccharide pyruvyl transferase AUP74_RS12515 7f2977ac9f18a7ae8a0ab5cb6d36f3b8 387 Gene3D G3DSA:3.90.180.10 36 218 1.2E-66 T 11-11-2016 IPR011032 GroES-like AUP74_RS12515 7f2977ac9f18a7ae8a0ab5cb6d36f3b8 387 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 101 115 - T 11-11-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 AUP74_RS12515 7f2977ac9f18a7ae8a0ab5cb6d36f3b8 387 Pfam PF00107 Zinc-binding dehydrogenase 225 347 7.3E-15 T 11-11-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AUP74_RS12515 7f2977ac9f18a7ae8a0ab5cb6d36f3b8 387 Gene3D G3DSA:3.40.50.720 219 323 2.2E-17 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS12515 7f2977ac9f18a7ae8a0ab5cb6d36f3b8 387 SUPERFAMILY SSF50129 48 210 4.26E-53 T 11-11-2016 IPR011032 GroES-like AUP74_RS12515 7f2977ac9f18a7ae8a0ab5cb6d36f3b8 387 SMART SM00829 50 382 2.8E-6 T 11-11-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AUP74_RS12515 7f2977ac9f18a7ae8a0ab5cb6d36f3b8 387 SUPERFAMILY SSF51735 188 352 2.08E-33 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS12515 7f2977ac9f18a7ae8a0ab5cb6d36f3b8 387 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 68 183 2.4E-28 T 11-11-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AUP74_RS05185 264448a38bc1a5f3c2cee1cc47e114aa 469 SMART SM00998 377 456 2.3E-17 T 11-11-2016 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AUP74_RS05185 264448a38bc1a5f3c2cee1cc47e114aa 469 Gene3D G3DSA:1.10.40.30 385 455 1.2E-20 T 11-11-2016 AUP74_RS05185 264448a38bc1a5f3c2cee1cc47e114aa 469 Pfam PF10397 Adenylosuccinate lyase C-terminus 378 455 4.5E-13 T 11-11-2016 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AUP74_RS05185 264448a38bc1a5f3c2cee1cc47e114aa 469 Gene3D G3DSA:1.20.200.10 117 384 1.1E-65 T 11-11-2016 AUP74_RS05185 264448a38bc1a5f3c2cee1cc47e114aa 469 ProSitePatterns PS00163 Fumarate lyases signature. 291 300 - T 11-11-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 AUP74_RS05185 264448a38bc1a5f3c2cee1cc47e114aa 469 PRINTS PR00145 Argininosuccinate lyase family signature 154 174 6.6E-10 T 11-11-2016 AUP74_RS05185 264448a38bc1a5f3c2cee1cc47e114aa 469 PRINTS PR00145 Argininosuccinate lyase family signature 246 270 6.6E-10 T 11-11-2016 AUP74_RS05185 264448a38bc1a5f3c2cee1cc47e114aa 469 PRINTS PR00145 Argininosuccinate lyase family signature 291 307 6.6E-10 T 11-11-2016 AUP74_RS05185 264448a38bc1a5f3c2cee1cc47e114aa 469 PRINTS PR00149 Fumarate lyase superfamily signature 159 177 2.9E-22 T 11-11-2016 IPR000362 Fumarate lyase family AUP74_RS05185 264448a38bc1a5f3c2cee1cc47e114aa 469 PRINTS PR00149 Fumarate lyase superfamily signature 114 132 2.9E-22 T 11-11-2016 IPR000362 Fumarate lyase family AUP74_RS05185 264448a38bc1a5f3c2cee1cc47e114aa 469 PRINTS PR00149 Fumarate lyase superfamily signature 246 273 2.9E-22 T 11-11-2016 IPR000362 Fumarate lyase family AUP74_RS05185 264448a38bc1a5f3c2cee1cc47e114aa 469 PRINTS PR00149 Fumarate lyase superfamily signature 291 307 2.9E-22 T 11-11-2016 IPR000362 Fumarate lyase family AUP74_RS05185 264448a38bc1a5f3c2cee1cc47e114aa 469 Gene3D G3DSA:1.10.275.10 28 116 1.0E-22 T 11-11-2016 IPR024083 Fumarase/histidase, N-terminal AUP74_RS05185 264448a38bc1a5f3c2cee1cc47e114aa 469 Pfam PF00206 Lyase 27 311 1.4E-42 T 11-11-2016 IPR022761 Fumarate lyase, N-terminal AUP74_RS05185 264448a38bc1a5f3c2cee1cc47e114aa 469 SUPERFAMILY SSF48557 30 461 9.27E-89 T 11-11-2016 IPR008948 L-Aspartase-like GO:0003824 AUP74_RS03275 bc040ba41f5546660f99345508f6f78b 480 Gene3D G3DSA:1.10.150.130 118 240 5.1E-8 T 11-11-2016 IPR023109 Integrase/recombinase, N-terminal AUP74_RS03275 bc040ba41f5546660f99345508f6f78b 480 SUPERFAMILY SSF56349 205 443 8.71E-39 T 11-11-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AUP74_RS03275 bc040ba41f5546660f99345508f6f78b 480 SUPERFAMILY SSF56349 118 177 8.71E-39 T 11-11-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AUP74_RS03275 bc040ba41f5546660f99345508f6f78b 480 Gene3D G3DSA:1.10.443.10 278 435 1.4E-21 T 11-11-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 AUP74_RS03275 bc040ba41f5546660f99345508f6f78b 480 Pfam PF00589 Phage integrase family 283 434 5.5E-12 T 11-11-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AUP74_RS13885 d6dd297a2ac47bfdb8c3dc386cdcd149 434 Pfam PF01979 Amidohydrolase family 299 392 1.2E-6 T 11-11-2016 IPR006680 Amidohydrolase-related GO:0016787 AUP74_RS13885 d6dd297a2ac47bfdb8c3dc386cdcd149 434 SUPERFAMILY SSF51338 24 78 1.17E-23 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS13885 d6dd297a2ac47bfdb8c3dc386cdcd149 434 SUPERFAMILY SSF51338 374 414 1.17E-23 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS13885 d6dd297a2ac47bfdb8c3dc386cdcd149 434 Gene3D G3DSA:2.30.40.10 18 135 3.0E-19 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS13885 d6dd297a2ac47bfdb8c3dc386cdcd149 434 Gene3D G3DSA:2.30.40.10 312 407 1.8E-15 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS13885 d6dd297a2ac47bfdb8c3dc386cdcd149 434 SUPERFAMILY SSF51556 281 373 2.89E-7 T 11-11-2016 IPR032466 Metal-dependent hydrolase AUP74_RS04255 3f33e0caf47349634562eb972e06ae91 130 Gene3D G3DSA:3.10.129.10 10 129 1.1E-34 T 11-11-2016 IPR029069 HotDog domain AUP74_RS04255 3f33e0caf47349634562eb972e06ae91 130 Pfam PF03061 Thioesterase superfamily 28 97 1.1E-15 T 11-11-2016 IPR006683 Thioesterase domain Reactome: R-HSA-75105 AUP74_RS04255 3f33e0caf47349634562eb972e06ae91 130 SUPERFAMILY SSF54637 10 129 8.57E-36 T 11-11-2016 IPR029069 HotDog domain AUP74_RS02905 b064466c48d803a0b6ebab6938172d58 132 Gene3D G3DSA:1.10.490.10 3 131 1.5E-39 T 11-11-2016 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 AUP74_RS02905 b064466c48d803a0b6ebab6938172d58 132 SUPERFAMILY SSF46458 7 132 2.04E-31 T 11-11-2016 IPR009050 Globin-like AUP74_RS04555 6a00fb2bc8fd6918eb2ddd1e43f092bb 461 SUPERFAMILY SSF116726 135 222 4.32E-12 T 11-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AUP74_RS04555 6a00fb2bc8fd6918eb2ddd1e43f092bb 461 SUPERFAMILY SSF116726 360 440 7.98E-7 T 11-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AUP74_RS04555 6a00fb2bc8fd6918eb2ddd1e43f092bb 461 Pfam PF02080 TrkA-C domain 155 224 7.0E-13 T 11-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AUP74_RS04555 6a00fb2bc8fd6918eb2ddd1e43f092bb 461 Pfam PF02080 TrkA-C domain 390 441 2.1E-7 T 11-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AUP74_RS04555 6a00fb2bc8fd6918eb2ddd1e43f092bb 461 SUPERFAMILY SSF51735 1 151 1.97E-37 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS04555 6a00fb2bc8fd6918eb2ddd1e43f092bb 461 Pfam PF02254 TrkA-N domain 235 349 1.9E-23 T 11-11-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 AUP74_RS04555 6a00fb2bc8fd6918eb2ddd1e43f092bb 461 Pfam PF02254 TrkA-N domain 3 107 7.5E-29 T 11-11-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 AUP74_RS04555 6a00fb2bc8fd6918eb2ddd1e43f092bb 461 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 7.2E-27 T 11-11-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 AUP74_RS04555 6a00fb2bc8fd6918eb2ddd1e43f092bb 461 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 7.2E-27 T 11-11-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 AUP74_RS04555 6a00fb2bc8fd6918eb2ddd1e43f092bb 461 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 7.2E-27 T 11-11-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 AUP74_RS04555 6a00fb2bc8fd6918eb2ddd1e43f092bb 461 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 7.2E-27 T 11-11-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 AUP74_RS04555 6a00fb2bc8fd6918eb2ddd1e43f092bb 461 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 7.2E-27 T 11-11-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 AUP74_RS04555 6a00fb2bc8fd6918eb2ddd1e43f092bb 461 SUPERFAMILY SSF51735 232 375 1.55E-32 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS04555 6a00fb2bc8fd6918eb2ddd1e43f092bb 461 Gene3D G3DSA:3.30.70.1450 152 222 1.5E-7 T 11-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AUP74_RS04555 6a00fb2bc8fd6918eb2ddd1e43f092bb 461 Gene3D G3DSA:3.40.50.720 1 151 4.2E-49 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS04555 6a00fb2bc8fd6918eb2ddd1e43f092bb 461 Gene3D G3DSA:3.40.50.720 232 375 8.7E-36 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS09150 360faebc79805333d3dc8305d9272aa7 258 Gene3D G3DSA:1.25.40.10 38 235 2.0E-31 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS09150 360faebc79805333d3dc8305d9272aa7 258 SMART SM00028 73 106 0.59 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS09150 360faebc79805333d3dc8305d9272aa7 258 SMART SM00028 107 140 120.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS09150 360faebc79805333d3dc8305d9272aa7 258 SMART SM00028 143 176 0.025 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS09150 360faebc79805333d3dc8305d9272aa7 258 SMART SM00028 177 210 240.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS09150 360faebc79805333d3dc8305d9272aa7 258 SMART SM00028 38 72 190.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS09150 360faebc79805333d3dc8305d9272aa7 258 SUPERFAMILY SSF81901 45 207 4.71E-23 T 11-11-2016 AUP74_RS09150 360faebc79805333d3dc8305d9272aa7 258 Pfam PF13424 Tetratricopeptide repeat 108 174 1.7E-10 T 11-11-2016 AUP74_RS09150 360faebc79805333d3dc8305d9272aa7 258 TIGRFAM TIGR02521 type_IV_pilW: type IV pilus biogenesis/stability protein PilW 12 242 1.8E-64 T 11-11-2016 IPR013360 Pilus biogenesis/stability type IV, PilW AUP74_RS16540 a77c241edb3532dd9861a81b232628be 290 Gene3D G3DSA:3.40.50.720 2 119 7.0E-57 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS16540 a77c241edb3532dd9861a81b232628be 290 Pfam PF00549 CoA-ligase 151 270 3.8E-21 T 11-11-2016 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AUP74_RS16540 a77c241edb3532dd9861a81b232628be 290 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 11-11-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 AUP74_RS16540 a77c241edb3532dd9861a81b232628be 290 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 4 286 4.2E-147 T 11-11-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 AUP74_RS16540 a77c241edb3532dd9861a81b232628be 290 SUPERFAMILY SSF52210 123 285 2.88E-58 T 11-11-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AUP74_RS16540 a77c241edb3532dd9861a81b232628be 290 Gene3D G3DSA:3.40.50.261 120 287 9.8E-80 T 11-11-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AUP74_RS16540 a77c241edb3532dd9861a81b232628be 290 SMART SM00881 4 100 3.0E-39 T 11-11-2016 IPR003781 CoA-binding GO:0048037 AUP74_RS16540 a77c241edb3532dd9861a81b232628be 290 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 1.8E-40 T 11-11-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 AUP74_RS16540 a77c241edb3532dd9861a81b232628be 290 PRINTS PR01798 Succinyl-CoA synthase signature 240 257 1.8E-40 T 11-11-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 AUP74_RS16540 a77c241edb3532dd9861a81b232628be 290 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 1.8E-40 T 11-11-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 AUP74_RS16540 a77c241edb3532dd9861a81b232628be 290 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 1.8E-40 T 11-11-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 AUP74_RS16540 a77c241edb3532dd9861a81b232628be 290 SUPERFAMILY SSF51735 1 122 2.11E-44 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS16540 a77c241edb3532dd9861a81b232628be 290 PIRSF PIRSF001553 1 289 5.1E-136 T 11-11-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 AUP74_RS16540 a77c241edb3532dd9861a81b232628be 290 Pfam PF02629 CoA binding domain 6 99 2.5E-33 T 11-11-2016 IPR003781 CoA-binding GO:0048037 AUP74_RS16540 a77c241edb3532dd9861a81b232628be 290 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 236 249 - T 11-11-2016 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site AUP74_RS13480 34e59fc672e31dafbb7d466954483dc3 283 SUPERFAMILY SSF81324 22 233 4.32E-52 T 11-11-2016 AUP74_RS13480 34e59fc672e31dafbb7d466954483dc3 283 PRINTS PR00169 Potassium channel signature 84 104 2.4E-30 T 11-11-2016 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 AUP74_RS13480 34e59fc672e31dafbb7d466954483dc3 283 PRINTS PR00169 Potassium channel signature 58 81 2.4E-30 T 11-11-2016 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 AUP74_RS13480 34e59fc672e31dafbb7d466954483dc3 283 PRINTS PR00169 Potassium channel signature 178 200 2.4E-30 T 11-11-2016 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 AUP74_RS13480 34e59fc672e31dafbb7d466954483dc3 283 PRINTS PR00169 Potassium channel signature 149 172 2.4E-30 T 11-11-2016 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 AUP74_RS13480 34e59fc672e31dafbb7d466954483dc3 283 PRINTS PR00169 Potassium channel signature 120 146 2.4E-30 T 11-11-2016 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 AUP74_RS13480 34e59fc672e31dafbb7d466954483dc3 283 PRINTS PR00169 Potassium channel signature 207 233 2.4E-30 T 11-11-2016 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 AUP74_RS13480 34e59fc672e31dafbb7d466954483dc3 283 Gene3D G3DSA:1.10.287.70 25 233 1.7E-49 T 11-11-2016 AUP74_RS13480 34e59fc672e31dafbb7d466954483dc3 283 Pfam PF00520 Ion transport protein 24 234 5.6E-27 T 11-11-2016 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 AUP74_RS10640 d645b4268dc96bdcb7673e543624ed37 464 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 229 409 1.6E-37 T 11-11-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 AUP74_RS10640 d645b4268dc96bdcb7673e543624ed37 464 SMART SM00044 194 399 1.5E-23 T 11-11-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 AUP74_RS10640 d645b4268dc96bdcb7673e543624ed37 464 SUPERFAMILY SSF55073 225 410 2.51E-58 T 11-11-2016 IPR029787 Nucleotide cyclase AUP74_RS10640 d645b4268dc96bdcb7673e543624ed37 464 Pfam PF05230 MASE2 domain 48 109 8.6E-6 T 11-11-2016 IPR007894 MASE2 AUP74_RS10640 d645b4268dc96bdcb7673e543624ed37 464 Gene3D G3DSA:3.30.70.1230 226 412 4.0E-52 T 11-11-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 AUP74_RS14490 a1bcd6a845cade15784d0001da629f78 867 Pfam PF07715 TonB-dependent Receptor Plug Domain 54 166 4.4E-18 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS14490 a1bcd6a845cade15784d0001da629f78 867 Pfam PF00593 TonB dependent receptor 588 866 7.4E-27 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS14490 a1bcd6a845cade15784d0001da629f78 867 SUPERFAMILY SSF56935 35 284 3.43E-108 T 11-11-2016 AUP74_RS14490 a1bcd6a845cade15784d0001da629f78 867 SUPERFAMILY SSF56935 343 867 3.43E-108 T 11-11-2016 AUP74_RS14490 a1bcd6a845cade15784d0001da629f78 867 Gene3D G3DSA:2.40.170.20 177 270 6.3E-75 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS14490 a1bcd6a845cade15784d0001da629f78 867 Gene3D G3DSA:2.40.170.20 331 867 6.3E-75 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS14490 a1bcd6a845cade15784d0001da629f78 867 Gene3D G3DSA:2.170.130.10 35 176 1.9E-34 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS09525 da1ba4ce5bd4b0e14e4a831da1ad0975 188 SMART SM00644 19 170 2.9E-51 T 11-11-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 AUP74_RS09525 da1ba4ce5bd4b0e14e4a831da1ad0975 188 Gene3D G3DSA:3.40.80.10 7 184 5.5E-68 T 11-11-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 AUP74_RS09525 da1ba4ce5bd4b0e14e4a831da1ad0975 188 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 30 171 2.0E-20 T 11-11-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 AUP74_RS09525 da1ba4ce5bd4b0e14e4a831da1ad0975 188 SUPERFAMILY SSF55846 6 183 4.19E-66 T 11-11-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 AUP74_RS05640 d33a556a8046db14202fd9725fddeaa4 526 Gene3D G3DSA:3.40.50.300 279 505 1.3E-21 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05640 d33a556a8046db14202fd9725fddeaa4 526 Pfam PF13469 Sulfotransferase family 283 471 7.2E-42 T 11-11-2016 AUP74_RS05640 d33a556a8046db14202fd9725fddeaa4 526 Pfam PF14559 Tetratricopeptide repeat 54 115 2.4E-6 T 11-11-2016 AUP74_RS05640 d33a556a8046db14202fd9725fddeaa4 526 SMART SM00028 74 107 460.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS05640 d33a556a8046db14202fd9725fddeaa4 526 SMART SM00028 108 141 12.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS05640 d33a556a8046db14202fd9725fddeaa4 526 SMART SM00028 40 73 0.031 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS05640 d33a556a8046db14202fd9725fddeaa4 526 SMART SM00028 212 245 85.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS05640 d33a556a8046db14202fd9725fddeaa4 526 SMART SM00028 142 175 0.27 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS05640 d33a556a8046db14202fd9725fddeaa4 526 Gene3D G3DSA:1.25.40.10 10 246 9.9E-32 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS05640 d33a556a8046db14202fd9725fddeaa4 526 SUPERFAMILY SSF48452 37 243 1.52E-25 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS05640 d33a556a8046db14202fd9725fddeaa4 526 SUPERFAMILY SSF52540 256 507 1.36E-49 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS13460 ca5eba0068115378a9804d573bf86943 216 Gene3D G3DSA:3.30.1330.60 92 212 1.4E-39 T 11-11-2016 IPR006665 OmpA-like domain AUP74_RS13460 ca5eba0068115378a9804d573bf86943 216 ProSitePatterns PS01068 OmpA-like domain. 144 188 - T 11-11-2016 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 AUP74_RS13460 ca5eba0068115378a9804d573bf86943 216 Pfam PF00691 OmpA family 111 206 8.4E-22 T 11-11-2016 IPR006665 OmpA-like domain AUP74_RS13460 ca5eba0068115378a9804d573bf86943 216 PRINTS PR01021 OMPA domain signature 157 173 3.3E-14 T 11-11-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AUP74_RS13460 ca5eba0068115378a9804d573bf86943 216 PRINTS PR01021 OMPA domain signature 142 157 3.3E-14 T 11-11-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AUP74_RS13460 ca5eba0068115378a9804d573bf86943 216 PRINTS PR01021 OMPA domain signature 112 134 3.3E-14 T 11-11-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AUP74_RS13460 ca5eba0068115378a9804d573bf86943 216 SUPERFAMILY SSF103088 99 215 7.72E-39 T 11-11-2016 IPR006665 OmpA-like domain AUP74_RS13460 ca5eba0068115378a9804d573bf86943 216 Pfam PF13488 Glycine zipper 34 81 9.1E-11 T 11-11-2016 AUP74_RS15215 14e20557329b99c8b5fb4a1b7fe1397e 165 Pfam PF10882 Bacterial PH domain 67 163 3.1E-13 T 11-11-2016 IPR027783 Bacterial Pleckstrin homology domain-related AUP74_RS09440 0c66efb39c0284c6b33bb4ec98fcd4e2 230 SUPERFAMILY SSF53098 14 211 5.57E-56 T 11-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 AUP74_RS09440 0c66efb39c0284c6b33bb4ec98fcd4e2 230 TIGRFAM TIGR01298 RNaseT: ribonuclease T 14 212 2.3E-99 T 11-11-2016 IPR005987 Ribonuclease T GO:0004540|GO:0006396 AUP74_RS09440 0c66efb39c0284c6b33bb4ec98fcd4e2 230 Pfam PF00929 Exonuclease 24 198 1.8E-30 T 11-11-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III AUP74_RS09440 0c66efb39c0284c6b33bb4ec98fcd4e2 230 Gene3D G3DSA:3.30.420.10 15 213 2.4E-55 T 11-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 AUP74_RS09440 0c66efb39c0284c6b33bb4ec98fcd4e2 230 Hamap MF_00157 Ribonuclease T [rnt]. 1 230 102.579 T 11-11-2016 IPR005987 Ribonuclease T GO:0004540|GO:0006396 AUP74_RS09440 0c66efb39c0284c6b33bb4ec98fcd4e2 230 SMART SM00479 22 207 8.2E-25 T 11-11-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III AUP74_RS03465 0504654a2606966ab8572989abc0acf0 685 SUPERFAMILY SSF56935 23 685 1.01E-83 T 11-11-2016 AUP74_RS03465 0504654a2606966ab8572989abc0acf0 685 Gene3D G3DSA:2.170.130.10 13 138 1.4E-15 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS03465 0504654a2606966ab8572989abc0acf0 685 Pfam PF00593 TonB dependent receptor 430 679 9.2E-26 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS03465 0504654a2606966ab8572989abc0acf0 685 Gene3D G3DSA:2.40.170.20 139 685 3.7E-63 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS03465 0504654a2606966ab8572989abc0acf0 685 TIGRFAM TIGR01778 TonB-copper: TonB-dependent copper receptor 38 685 2.1E-203 T 11-11-2016 IPR010100 TonB-dependent copper receptor AUP74_RS03465 0504654a2606966ab8572989abc0acf0 685 Pfam PF07715 TonB-dependent Receptor Plug Domain 41 137 5.2E-12 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS04415 543118d1060a2d6faebca9ec607a72fe 82 PRINTS PR00124 ATP synthase C subunit signature 48 73 6.8E-10 T 11-11-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 AUP74_RS04415 543118d1060a2d6faebca9ec607a72fe 82 PRINTS PR00124 ATP synthase C subunit signature 10 29 6.8E-10 T 11-11-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 AUP74_RS04415 543118d1060a2d6faebca9ec607a72fe 82 PRINTS PR00124 ATP synthase C subunit signature 31 46 6.8E-10 T 11-11-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 AUP74_RS04415 543118d1060a2d6faebca9ec607a72fe 82 Gene3D G3DSA:1.20.20.10 3 75 4.0E-29 T 11-11-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 AUP74_RS04415 543118d1060a2d6faebca9ec607a72fe 82 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 19 75 9.5E-27 T 11-11-2016 IPR005953 ATPase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 AUP74_RS04415 543118d1060a2d6faebca9ec607a72fe 82 ProSitePatterns PS00605 ATP synthase c subunit signature. 38 59 - T 11-11-2016 IPR020537 ATPase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210 AUP74_RS04415 543118d1060a2d6faebca9ec607a72fe 82 Hamap MF_01396 ATP synthase subunit c [atpH]. 7 75 14.357 T 11-11-2016 AUP74_RS04415 543118d1060a2d6faebca9ec607a72fe 82 SUPERFAMILY SSF81333 4 75 2.09E-17 T 11-11-2016 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 AUP74_RS04415 543118d1060a2d6faebca9ec607a72fe 82 Pfam PF00137 ATP synthase subunit C 9 72 1.9E-9 T 11-11-2016 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 AUP74_RS11885 4c5626dd3cb3d8054cdb8dc8592ecf90 368 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 215 249 - T 11-11-2016 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 AUP74_RS11885 4c5626dd3cb3d8054cdb8dc8592ecf90 368 Gene3D G3DSA:2.30.30.60 199 249 2.8E-16 T 11-11-2016 AUP74_RS11885 4c5626dd3cb3d8054cdb8dc8592ecf90 368 SUPERFAMILY SSF82861 102 182 4.58E-14 T 11-11-2016 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 AUP74_RS11885 4c5626dd3cb3d8054cdb8dc8592ecf90 368 SUPERFAMILY SSF82689 252 355 1.57E-18 T 11-11-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 AUP74_RS11885 4c5626dd3cb3d8054cdb8dc8592ecf90 368 Pfam PF00924 Mechanosensitive ion channel 141 344 2.5E-55 T 11-11-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 AUP74_RS11885 4c5626dd3cb3d8054cdb8dc8592ecf90 368 SUPERFAMILY SSF50182 183 250 4.25E-17 T 11-11-2016 IPR010920 LSM domain AUP74_RS11885 4c5626dd3cb3d8054cdb8dc8592ecf90 368 Gene3D G3DSA:3.30.70.100 255 342 1.6E-11 T 11-11-2016 AUP74_RS06875 03a15b64ea3c198783ef38697da2034a 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 11-11-2016 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06875 03a15b64ea3c198783ef38697da2034a 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 9.4E-55 T 11-11-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 AUP74_RS06875 03a15b64ea3c198783ef38697da2034a 122 SUPERFAMILY SSF50193 1 122 6.28E-52 T 11-11-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 AUP74_RS06875 03a15b64ea3c198783ef38697da2034a 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 28.164 T 11-11-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 AUP74_RS06875 03a15b64ea3c198783ef38697da2034a 122 SMART SM01374 1 122 2.3E-86 T 11-11-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 AUP74_RS06875 03a15b64ea3c198783ef38697da2034a 122 Gene3D G3DSA:2.40.150.20 1 122 1.0E-54 T 11-11-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 AUP74_RS06875 03a15b64ea3c198783ef38697da2034a 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 7.9E-59 T 11-11-2016 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 AUP74_RS04775 c959c93ed4c958d739efa61b90ca483a 282 Gene3D G3DSA:3.40.50.1980 15 156 2.5E-27 T 11-11-2016 AUP74_RS04775 c959c93ed4c958d739efa61b90ca483a 282 Pfam PF01297 Zinc-uptake complex component A periplasmic 16 257 4.8E-31 T 11-11-2016 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 AUP74_RS04775 c959c93ed4c958d739efa61b90ca483a 282 SUPERFAMILY SSF53807 11 265 5.4E-39 T 11-11-2016 AUP74_RS08235 ed5f1814644533b17dced8c619f16990 290 PIRSF PIRSF016020 21 290 1.4E-49 T 11-11-2016 IPR025532 Glucose-6-phosphate 1-epimerase AUP74_RS08235 ed5f1814644533b17dced8c619f16990 290 Pfam PF01263 Aldose 1-epimerase 27 286 3.6E-35 T 11-11-2016 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 AUP74_RS08235 ed5f1814644533b17dced8c619f16990 290 SUPERFAMILY SSF74650 21 286 8.16E-53 T 11-11-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 AUP74_RS08235 ed5f1814644533b17dced8c619f16990 290 Gene3D G3DSA:2.70.98.10 20 285 1.9E-62 T 11-11-2016 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 AUP74_RS15270 9d58fa1f4d54703cd9415902e773f3c5 335 SUPERFAMILY SSF52374 5 331 4.02E-84 T 11-11-2016 AUP74_RS15270 9d58fa1f4d54703cd9415902e773f3c5 335 Pfam PF00579 tRNA synthetases class I (W and Y) 4 283 2.7E-53 T 11-11-2016 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS15270 9d58fa1f4d54703cd9415902e773f3c5 335 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 202 212 2.4E-18 T 11-11-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AUP74_RS15270 9d58fa1f4d54703cd9415902e773f3c5 335 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 151 172 2.4E-18 T 11-11-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AUP74_RS15270 9d58fa1f4d54703cd9415902e773f3c5 335 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 68 87 2.4E-18 T 11-11-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AUP74_RS15270 9d58fa1f4d54703cd9415902e773f3c5 335 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 16 32 2.4E-18 T 11-11-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AUP74_RS15270 9d58fa1f4d54703cd9415902e773f3c5 335 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 3 331 3.8E-89 T 11-11-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AUP74_RS15270 9d58fa1f4d54703cd9415902e773f3c5 335 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 3 332 35.483 T 11-11-2016 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 AUP74_RS15270 9d58fa1f4d54703cd9415902e773f3c5 335 Gene3D G3DSA:1.10.240.10 212 298 2.6E-28 T 11-11-2016 AUP74_RS15270 9d58fa1f4d54703cd9415902e773f3c5 335 Gene3D G3DSA:3.40.50.620 3 211 4.8E-75 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS09105 e52f4251a9e9ea82dd50745e0845e78e 404 TIGRFAM TIGR02006 IscS: cysteine desulfurase IscS 1 404 6.4E-225 T 11-11-2016 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 AUP74_RS09105 e52f4251a9e9ea82dd50745e0845e78e 404 Gene3D G3DSA:3.90.1150.10 255 374 2.4E-49 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS09105 e52f4251a9e9ea82dd50745e0845e78e 404 PIRSF PIRSF005572 2 384 2.0E-131 T 11-11-2016 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 AUP74_RS09105 e52f4251a9e9ea82dd50745e0845e78e 404 SUPERFAMILY SSF53383 5 390 2.18E-111 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase AUP74_RS09105 e52f4251a9e9ea82dd50745e0845e78e 404 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 197 216 - T 11-11-2016 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site AUP74_RS09105 e52f4251a9e9ea82dd50745e0845e78e 404 Gene3D G3DSA:3.40.640.10 17 254 3.2E-95 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AUP74_RS09105 e52f4251a9e9ea82dd50745e0845e78e 404 Hamap MF_00331 Cysteine desulfurase IscS [iscS]. 1 395 52.937 T 11-11-2016 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 AUP74_RS09105 e52f4251a9e9ea82dd50745e0845e78e 404 Pfam PF00266 Aminotransferase class-V 5 367 8.2E-86 T 11-11-2016 IPR000192 Aminotransferase class V domain AUP74_RS01860 bba4e484abc5f427ddfee9e97b26023c 648 Pfam PF00330 Aconitase family (aconitate hydratase) 10 407 9.2E-87 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS01860 bba4e484abc5f427ddfee9e97b26023c 648 SUPERFAMILY SSF53732 2 423 2.75E-126 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS01860 bba4e484abc5f427ddfee9e97b26023c 648 Gene3D G3DSA:3.30.499.10 25 154 5.1E-41 T 11-11-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS01860 bba4e484abc5f427ddfee9e97b26023c 648 SUPERFAMILY SSF52016 442 642 5.89E-52 T 11-11-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel AUP74_RS01860 bba4e484abc5f427ddfee9e97b26023c 648 Gene3D G3DSA:3.30.499.10 270 460 8.0E-47 T 11-11-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS01860 bba4e484abc5f427ddfee9e97b26023c 648 TIGRFAM TIGR01342 acon_putative: putative aconitate hydratase 5 643 4.4E-246 T 11-11-2016 IPR006250 Aconitase, putative AUP74_RS01860 bba4e484abc5f427ddfee9e97b26023c 648 PRINTS PR00415 Aconitase family signature 200 213 1.6E-16 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS01860 bba4e484abc5f427ddfee9e97b26023c 648 PRINTS PR00415 Aconitase family signature 110 123 1.6E-16 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS01860 bba4e484abc5f427ddfee9e97b26023c 648 PRINTS PR00415 Aconitase family signature 124 139 1.6E-16 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS01860 bba4e484abc5f427ddfee9e97b26023c 648 PRINTS PR00415 Aconitase family signature 186 199 1.6E-16 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS01860 bba4e484abc5f427ddfee9e97b26023c 648 PRINTS PR00415 Aconitase family signature 349 362 1.6E-16 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS01860 bba4e484abc5f427ddfee9e97b26023c 648 Gene3D G3DSA:3.20.19.10 461 641 1.6E-48 T 11-11-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel AUP74_RS01860 bba4e484abc5f427ddfee9e97b26023c 648 Gene3D G3DSA:3.40.1060.10 158 262 6.6E-33 T 11-11-2016 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS01860 bba4e484abc5f427ddfee9e97b26023c 648 Pfam PF00694 Aconitase C-terminal domain 508 576 4.8E-24 T 11-11-2016 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS03680 a24b2c70f96dfa1fd1d5bbb6ade2d316 339 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 225 1.8E-27 T 11-11-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 AUP74_RS03680 a24b2c70f96dfa1fd1d5bbb6ade2d316 339 Gene3D G3DSA:3.40.50.720 1 214 1.1E-41 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS03680 a24b2c70f96dfa1fd1d5bbb6ade2d316 339 Gene3D G3DSA:3.90.25.10 215 322 3.6E-11 T 11-11-2016 AUP74_RS03680 a24b2c70f96dfa1fd1d5bbb6ade2d316 339 SUPERFAMILY SSF51735 1 261 2.75E-58 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS03680 a24b2c70f96dfa1fd1d5bbb6ade2d316 339 SUPERFAMILY SSF51735 289 325 2.75E-58 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS05515 619eeaae2b040666bd1296d5c0198e04 655 Gene3D G3DSA:3.40.50.300 59 107 1.1E-14 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05515 619eeaae2b040666bd1296d5c0198e04 655 Gene3D G3DSA:3.40.50.300 203 312 1.1E-14 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05515 619eeaae2b040666bd1296d5c0198e04 655 Pfam PF00350 Dynamin family 59 249 1.9E-12 T 11-11-2016 IPR022812 Dynamin superfamily AUP74_RS05515 619eeaae2b040666bd1296d5c0198e04 655 SUPERFAMILY SSF52540 43 143 4.31E-20 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05515 619eeaae2b040666bd1296d5c0198e04 655 SUPERFAMILY SSF52540 186 313 4.31E-20 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS02305 0446cc345b10c93b24da629eeade4771 216 Gene3D G3DSA:3.30.1150.10 129 214 4.5E-7 T 11-11-2016 AUP74_RS02305 0446cc345b10c93b24da629eeade4771 216 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 130 214 5.3E-17 T 11-11-2016 IPR006260 TonB, C-terminal GO:0006810 AUP74_RS02305 0446cc345b10c93b24da629eeade4771 216 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 132 214 7.2E-14 T 11-11-2016 IPR006260 TonB, C-terminal GO:0006810 AUP74_RS02305 0446cc345b10c93b24da629eeade4771 216 SUPERFAMILY SSF74653 124 203 1.83E-20 T 11-11-2016 AUP74_RS11285 859bac862a1f43f6a3a7bf72c9904f42 405 SUPERFAMILY SSF52151 1 231 1.57E-46 T 11-11-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 AUP74_RS11285 859bac862a1f43f6a3a7bf72c9904f42 405 Pfam PF01734 Patatin-like phospholipase 1 214 3.5E-27 T 11-11-2016 IPR002641 Patatin/Phospholipase A2-related GO:0006629 AUP74_RS11285 859bac862a1f43f6a3a7bf72c9904f42 405 Gene3D G3DSA:3.40.1090.10 1 214 8.1E-14 T 11-11-2016 AUP74_RS16040 789d240f09c55b1186363f648b050a3f 303 Gene3D G3DSA:3.40.50.300 18 179 8.0E-42 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS16040 789d240f09c55b1186363f648b050a3f 303 PIRSF PIRSF002849 1 301 1.2E-117 T 11-11-2016 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted AUP74_RS16040 789d240f09c55b1186363f648b050a3f 303 Gene3D G3DSA:1.10.8.300 198 294 5.1E-27 T 11-11-2016 AUP74_RS16040 789d240f09c55b1186363f648b050a3f 303 SUPERFAMILY SSF52540 7 279 5.63E-43 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS16040 789d240f09c55b1186363f648b050a3f 303 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 35 165 3.7E-62 T 11-11-2016 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 AUP74_RS03760 00e6578f705da8652dec234d50fd5ba1 950 Gene3D G3DSA:2.170.130.10 58 173 2.6E-30 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS03760 00e6578f705da8652dec234d50fd5ba1 950 Gene3D G3DSA:2.40.170.20 321 364 2.4E-73 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS03760 00e6578f705da8652dec234d50fd5ba1 950 Gene3D G3DSA:2.40.170.20 174 246 2.4E-73 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS03760 00e6578f705da8652dec234d50fd5ba1 950 Gene3D G3DSA:2.40.170.20 401 455 2.4E-73 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS03760 00e6578f705da8652dec234d50fd5ba1 950 Gene3D G3DSA:2.40.170.20 682 950 2.4E-73 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS03760 00e6578f705da8652dec234d50fd5ba1 950 Gene3D G3DSA:2.40.170.20 503 638 2.4E-73 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS03760 00e6578f705da8652dec234d50fd5ba1 950 Pfam PF07715 TonB-dependent Receptor Plug Domain 58 170 1.6E-19 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS03760 00e6578f705da8652dec234d50fd5ba1 950 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 933 950 - T 11-11-2016 IPR010917 TonB-dependent receptor, conserved site AUP74_RS03760 00e6578f705da8652dec234d50fd5ba1 950 SUPERFAMILY SSF56935 501 650 2.65E-87 T 11-11-2016 AUP74_RS03760 00e6578f705da8652dec234d50fd5ba1 950 SUPERFAMILY SSF56935 322 370 2.65E-87 T 11-11-2016 AUP74_RS03760 00e6578f705da8652dec234d50fd5ba1 950 SUPERFAMILY SSF56935 763 950 2.65E-87 T 11-11-2016 AUP74_RS03760 00e6578f705da8652dec234d50fd5ba1 950 SUPERFAMILY SSF56935 42 237 2.65E-87 T 11-11-2016 AUP74_RS03760 00e6578f705da8652dec234d50fd5ba1 950 SUPERFAMILY SSF56935 399 460 2.65E-87 T 11-11-2016 AUP74_RS03760 00e6578f705da8652dec234d50fd5ba1 950 SUPERFAMILY SSF56935 685 736 2.65E-87 T 11-11-2016 AUP74_RS03760 00e6578f705da8652dec234d50fd5ba1 950 Pfam PF00593 TonB dependent receptor 607 949 2.0E-23 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS05500 56a931dffa95f5d8375d051ea29f0d46 681 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 459 483 1.1E-5 T 11-11-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 AUP74_RS05500 56a931dffa95f5d8375d051ea29f0d46 681 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 575 590 1.1E-5 T 11-11-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 AUP74_RS05500 56a931dffa95f5d8375d051ea29f0d46 681 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 432 450 1.1E-5 T 11-11-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 AUP74_RS05500 56a931dffa95f5d8375d051ea29f0d46 681 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 517 537 1.1E-5 T 11-11-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 AUP74_RS05500 56a931dffa95f5d8375d051ea29f0d46 681 Pfam PF00326 Prolyl oligopeptidase family 448 658 1.6E-37 T 11-11-2016 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 AUP74_RS05500 56a931dffa95f5d8375d051ea29f0d46 681 SUPERFAMILY SSF82171 62 372 6.28E-37 T 11-11-2016 AUP74_RS05500 56a931dffa95f5d8375d051ea29f0d46 681 SUPERFAMILY SSF53474 406 658 5.58E-61 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS05500 56a931dffa95f5d8375d051ea29f0d46 681 Gene3D G3DSA:3.40.50.1820 314 658 2.7E-79 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS05500 56a931dffa95f5d8375d051ea29f0d46 681 Gene3D G3DSA:2.120.10.60 66 289 5.7E-30 T 11-11-2016 AUP74_RS05500 56a931dffa95f5d8375d051ea29f0d46 681 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 105 371 9.6E-10 T 11-11-2016 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 AUP74_RS01500 21b44edb3df6c174619941061641abac 595 Pfam PF05960 Bacterial protein of unknown function (DUF885) 38 569 1.4E-164 T 11-11-2016 IPR010281 Protein of unknown function DUF885 AUP74_RS01445 9c6b608a114b3db1bcecfd1a22032680 594 SUPERFAMILY SSF53383 139 544 1.31E-50 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase AUP74_RS01445 9c6b608a114b3db1bcecfd1a22032680 594 Gene3D G3DSA:3.40.640.10 136 409 5.3E-47 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AUP74_RS01445 9c6b608a114b3db1bcecfd1a22032680 594 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 136 543 2.5E-58 T 11-11-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AUP74_RS01445 9c6b608a114b3db1bcecfd1a22032680 594 Gene3D G3DSA:3.90.1150.10 410 543 1.6E-18 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS01690 e2a6f578653ce04df520bbeb4292dd61 331 Gene3D G3DSA:1.10.3470.10 6 327 3.1E-93 T 11-11-2016 IPR029022 ABC transporter, BtuC-like AUP74_RS01690 e2a6f578653ce04df520bbeb4292dd61 331 SUPERFAMILY SSF81345 8 322 5.49E-73 T 11-11-2016 IPR029022 ABC transporter, BtuC-like AUP74_RS01690 e2a6f578653ce04df520bbeb4292dd61 331 Pfam PF01032 FecCD transport family 17 323 1.1E-82 T 11-11-2016 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 AUP74_RS07005 77bfaf7a60e038b6d2368a8dc0ff05e2 407 Gene3D G3DSA:3.40.47.10 261 406 1.3E-49 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS07005 77bfaf7a60e038b6d2368a8dc0ff05e2 407 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 152 168 - T 11-11-2016 IPR018201 Beta-ketoacyl synthase, active site AUP74_RS07005 77bfaf7a60e038b6d2368a8dc0ff05e2 407 SMART SM00825 Beta-ketoacyl synthase 4 407 5.0E-11 T 11-11-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain AUP74_RS07005 77bfaf7a60e038b6d2368a8dc0ff05e2 407 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 252 364 6.9E-28 T 11-11-2016 IPR014031 Beta-ketoacyl synthase, C-terminal AUP74_RS07005 77bfaf7a60e038b6d2368a8dc0ff05e2 407 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 244 1.1E-44 T 11-11-2016 IPR014030 Beta-ketoacyl synthase, N-terminal AUP74_RS07005 77bfaf7a60e038b6d2368a8dc0ff05e2 407 SUPERFAMILY SSF53901 213 406 6.17E-61 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS07005 77bfaf7a60e038b6d2368a8dc0ff05e2 407 SUPERFAMILY SSF53901 1 251 2.74E-63 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS07005 77bfaf7a60e038b6d2368a8dc0ff05e2 407 Gene3D G3DSA:3.40.47.10 6 257 5.1E-58 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS00975 c8f7d97f4e2ed1ce9b0ef52197a2cdb1 159 Gene3D G3DSA:2.40.280.10 12 132 8.2E-48 T 11-11-2016 IPR023620 Small protein B AUP74_RS00975 c8f7d97f4e2ed1ce9b0ef52197a2cdb1 159 TIGRFAM TIGR00086 smpB: SsrA-binding protein 13 154 4.6E-51 T 11-11-2016 IPR000037 SsrA-binding protein GO:0003723 AUP74_RS00975 c8f7d97f4e2ed1ce9b0ef52197a2cdb1 159 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 13 137 5.0E-41 T 11-11-2016 IPR000037 SsrA-binding protein GO:0003723 AUP74_RS00975 c8f7d97f4e2ed1ce9b0ef52197a2cdb1 159 Pfam PF01668 SmpB protein 12 75 1.3E-27 T 11-11-2016 IPR000037 SsrA-binding protein GO:0003723 AUP74_RS00975 c8f7d97f4e2ed1ce9b0ef52197a2cdb1 159 Hamap MF_00023 SsrA-binding protein [smpB]. 1 159 68.995 T 11-11-2016 IPR000037 SsrA-binding protein GO:0003723 AUP74_RS00975 c8f7d97f4e2ed1ce9b0ef52197a2cdb1 159 SUPERFAMILY SSF74982 7 137 4.05E-47 T 11-11-2016 IPR023620 Small protein B AUP74_RS06325 c7406fe34e06e99caa123b195fe84399 71 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 11-11-2016 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS06325 c7406fe34e06e99caa123b195fe84399 71 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 15 42 7.0E-9 T 11-11-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06325 c7406fe34e06e99caa123b195fe84399 71 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 21.511 T 11-11-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06325 c7406fe34e06e99caa123b195fe84399 71 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 9.4E-16 T 11-11-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06325 c7406fe34e06e99caa123b195fe84399 71 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 9.4E-16 T 11-11-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06325 c7406fe34e06e99caa123b195fe84399 71 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 9.4E-16 T 11-11-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06325 c7406fe34e06e99caa123b195fe84399 71 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 9.4E-16 T 11-11-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06325 c7406fe34e06e99caa123b195fe84399 71 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 2 59 4.1E-24 T 11-11-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06325 c7406fe34e06e99caa123b195fe84399 71 Pfam PF01165 Ribosomal protein S21 4 56 1.5E-22 T 11-11-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS16465 01310f295add2a3b3a1a25e858b93888 208 SUPERFAMILY SSF141488 125 200 2.09E-8 T 11-11-2016 IPR018660 C-type lysozyme, inhibitor AUP74_RS16465 01310f295add2a3b3a1a25e858b93888 208 Pfam PF07007 Protein of unknown function (DUF1311) 39 116 4.2E-7 T 11-11-2016 IPR009739 Protein of unknown function DUF1311 AUP74_RS16465 01310f295add2a3b3a1a25e858b93888 208 Pfam PF09864 Membrane-bound lysozyme-inhibitor of c-type lysozyme 131 197 2.5E-9 T 11-11-2016 IPR018660 C-type lysozyme, inhibitor AUP74_RS06520 eb94037afc0ede7d0c81c537c40896c8 155 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 154 9.6E-60 T 11-11-2016 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 AUP74_RS06520 eb94037afc0ede7d0c81c537c40896c8 155 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 116 129 1.3E-17 T 11-11-2016 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 AUP74_RS06520 eb94037afc0ede7d0c81c537c40896c8 155 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 101 115 1.3E-17 T 11-11-2016 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 AUP74_RS06520 eb94037afc0ede7d0c81c537c40896c8 155 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 84 97 1.3E-17 T 11-11-2016 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 AUP74_RS06520 eb94037afc0ede7d0c81c537c40896c8 155 Pfam PF00364 Biotin-requiring enzyme 81 154 1.9E-26 T 11-11-2016 IPR000089 Biotin/lipoyl attachment AUP74_RS06520 eb94037afc0ede7d0c81c537c40896c8 155 Gene3D G3DSA:2.40.50.100 79 154 5.3E-33 T 11-11-2016 AUP74_RS06520 eb94037afc0ede7d0c81c537c40896c8 155 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 111 128 - T 11-11-2016 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AUP74_RS06520 eb94037afc0ede7d0c81c537c40896c8 155 SUPERFAMILY SSF51230 80 154 1.27E-25 T 11-11-2016 IPR011053 Single hybrid motif AUP74_RS09130 e0d63c6dbc35945d17e019209cdb0401 112 SUPERFAMILY SSF54292 4 106 6.51E-33 T 11-11-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AUP74_RS09130 e0d63c6dbc35945d17e019209cdb0401 112 PRINTS PR00355 Adrenodoxin signature 42 52 5.6E-9 T 11-11-2016 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 AUP74_RS09130 e0d63c6dbc35945d17e019209cdb0401 112 PRINTS PR00355 Adrenodoxin signature 60 74 5.6E-9 T 11-11-2016 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 AUP74_RS09130 e0d63c6dbc35945d17e019209cdb0401 112 PRINTS PR00355 Adrenodoxin signature 83 91 5.6E-9 T 11-11-2016 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 AUP74_RS09130 e0d63c6dbc35945d17e019209cdb0401 112 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 12 91 2.4E-13 T 11-11-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AUP74_RS09130 e0d63c6dbc35945d17e019209cdb0401 112 Gene3D G3DSA:3.10.20.30 1 101 5.8E-34 T 11-11-2016 IPR012675 Beta-grasp domain AUP74_RS09130 e0d63c6dbc35945d17e019209cdb0401 112 ProSitePatterns PS00814 Adrenodoxin family, iron-sulfur binding region signature. 42 52 - T 11-11-2016 IPR018298 Adrenodoxin, iron-sulphur binding site GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 AUP74_RS09130 e0d63c6dbc35945d17e019209cdb0401 112 TIGRFAM TIGR02007 fdx_isc: ferredoxin, 2Fe-2S type, ISC system 2 110 6.5E-58 T 11-11-2016 IPR011536 Ferredoxin 2Fe-2S type, proteobacteria GO:0009055|GO:0051537 AUP74_RS13235 1e383586bd49fb9d70bfd46ce4d369ba 152 TIGRFAM TIGR01068 thioredoxin: thioredoxin 47 145 1.3E-34 T 11-11-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 AUP74_RS13235 1e383586bd49fb9d70bfd46ce4d369ba 152 SUPERFAMILY SSF52833 30 148 5.35E-37 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS13235 1e383586bd49fb9d70bfd46ce4d369ba 152 ProSitePatterns PS00194 Thioredoxin family active site. 63 81 - T 11-11-2016 IPR017937 Thioredoxin, conserved site GO:0045454 AUP74_RS13235 1e383586bd49fb9d70bfd46ce4d369ba 152 Gene3D G3DSA:3.40.30.10 44 148 6.3E-35 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS13235 1e383586bd49fb9d70bfd46ce4d369ba 152 PRINTS PR00421 Thioredoxin family signature 110 121 1.4E-7 T 11-11-2016 AUP74_RS13235 1e383586bd49fb9d70bfd46ce4d369ba 152 PRINTS PR00421 Thioredoxin family signature 70 79 1.4E-7 T 11-11-2016 AUP74_RS13235 1e383586bd49fb9d70bfd46ce4d369ba 152 PRINTS PR00421 Thioredoxin family signature 62 70 1.4E-7 T 11-11-2016 AUP74_RS13235 1e383586bd49fb9d70bfd46ce4d369ba 152 Pfam PF00085 Thioredoxin 44 144 2.4E-29 T 11-11-2016 IPR013766 Thioredoxin domain GO:0045454 AUP74_RS08045 0d866cfc9d80871a2f5363940dca66d2 475 SUPERFAMILY SSF52467 292 463 5.01E-71 T 11-11-2016 IPR029035 DHS-like NAD/FAD-binding domain AUP74_RS08045 0d866cfc9d80871a2f5363940dca66d2 475 Gene3D G3DSA:3.40.50.1220 286 463 3.3E-86 T 11-11-2016 IPR029035 DHS-like NAD/FAD-binding domain AUP74_RS08045 0d866cfc9d80871a2f5363940dca66d2 475 Pfam PF02233 NAD(P) transhydrogenase beta subunit 6 459 1.0E-192 T 11-11-2016 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 AUP74_RS08045 0d866cfc9d80871a2f5363940dca66d2 475 PIRSF PIRSF000204 1 463 4.2E-206 T 11-11-2016 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 AUP74_RS02795 d8f0d6c3966564730a2f8df4b30a5d89 281 Pfam PF00753 Metallo-beta-lactamase superfamily 30 168 5.8E-7 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS02795 d8f0d6c3966564730a2f8df4b30a5d89 281 SUPERFAMILY SSF56281 7 267 1.82E-35 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS02795 d8f0d6c3966564730a2f8df4b30a5d89 281 SMART SM00849 27 196 6.7E-7 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS02795 d8f0d6c3966564730a2f8df4b30a5d89 281 Gene3D G3DSA:3.60.15.10 12 221 2.6E-30 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS00845 0961924dd80b890f17221829c87b5719 779 Pfam PF08487 Vault protein inter-alpha-trypsin domain 90 194 1.8E-30 T 11-11-2016 IPR013694 VIT domain AUP74_RS00845 0961924dd80b890f17221829c87b5719 779 Pfam PF13768 von Willebrand factor type A domain 383 536 1.6E-21 T 11-11-2016 IPR002035 von Willebrand factor, type A AUP74_RS00845 0961924dd80b890f17221829c87b5719 779 Gene3D G3DSA:3.40.50.410 380 549 1.0E-14 T 11-11-2016 IPR002035 von Willebrand factor, type A AUP74_RS00845 0961924dd80b890f17221829c87b5719 779 TIGRFAM TIGR03788 marine_srt_targ: marine proteobacterial sortase target protein 86 733 2.8E-221 T 11-11-2016 IPR022440 Conserved hypothetical protein CHP03788 AUP74_RS00845 0961924dd80b890f17221829c87b5719 779 SMART SM00327 381 546 9.6E-17 T 11-11-2016 IPR002035 von Willebrand factor, type A AUP74_RS00845 0961924dd80b890f17221829c87b5719 779 SMART SM00609 80 196 2.4E-7 T 11-11-2016 IPR013694 VIT domain AUP74_RS00845 0961924dd80b890f17221829c87b5719 779 SUPERFAMILY SSF53300 381 553 1.03E-26 T 11-11-2016 IPR002035 von Willebrand factor, type A AUP74_RS07130 30469ef516df3a7293dd9c4c79eb87f9 157 Pfam PF13633 Prokaryotic N-terminal methylation site 4 27 3.0E-5 T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS07130 30469ef516df3a7293dd9c4c79eb87f9 157 TIGRFAM TIGR02523 type_IV_pilV: type IV pilus modification protein PilV 4 130 2.3E-25 T 11-11-2016 IPR013362 Pilus modification type IV, PilV AUP74_RS15370 161b5fb5171bb1d906af20c5622d8ccf 223 Pfam PF14622 Ribonuclease-III-like 17 139 2.7E-34 T 11-11-2016 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 AUP74_RS15370 161b5fb5171bb1d906af20c5622d8ccf 223 Gene3D G3DSA:3.30.160.20 150 219 8.0E-24 T 11-11-2016 IPR014720 Double-stranded RNA-binding domain AUP74_RS15370 161b5fb5171bb1d906af20c5622d8ccf 223 SMART SM00535 18 146 1.4E-56 T 11-11-2016 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 AUP74_RS15370 161b5fb5171bb1d906af20c5622d8ccf 223 SMART SM00358 152 220 1.3E-20 T 11-11-2016 IPR014720 Double-stranded RNA-binding domain AUP74_RS15370 161b5fb5171bb1d906af20c5622d8ccf 223 ProSitePatterns PS00517 Ribonuclease III family signature. 35 43 - T 11-11-2016 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 AUP74_RS15370 161b5fb5171bb1d906af20c5622d8ccf 223 SUPERFAMILY SSF54768 107 219 4.87E-26 T 11-11-2016 AUP74_RS15370 161b5fb5171bb1d906af20c5622d8ccf 223 Gene3D G3DSA:1.10.1520.10 4 147 3.2E-44 T 11-11-2016 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 AUP74_RS15370 161b5fb5171bb1d906af20c5622d8ccf 223 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 9 219 8.1E-73 T 11-11-2016 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 AUP74_RS15370 161b5fb5171bb1d906af20c5622d8ccf 223 Pfam PF00035 Double-stranded RNA binding motif 152 219 1.7E-11 T 11-11-2016 IPR014720 Double-stranded RNA-binding domain AUP74_RS15370 161b5fb5171bb1d906af20c5622d8ccf 223 Hamap MF_00104 Ribonuclease 3 [rnc]. 2 216 29.323 T 11-11-2016 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 AUP74_RS15370 161b5fb5171bb1d906af20c5622d8ccf 223 SUPERFAMILY SSF69065 3 155 2.09E-48 T 11-11-2016 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 AUP74_RS10675 75b9eaf372f02dde2b54bae63b9b3b8c 481 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 190 243 2.4E-5 T 11-11-2016 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 AUP74_RS10675 75b9eaf372f02dde2b54bae63b9b3b8c 481 SUPERFAMILY SSF55931 38 458 2.55E-43 T 11-11-2016 AUP74_RS10675 75b9eaf372f02dde2b54bae63b9b3b8c 481 PIRSF PIRSF012666 1 481 1.1E-140 T 11-11-2016 IPR016602 Uncharacterised conserved protein UCP012666 AUP74_RS05860 d33ece54ba0fcb172c6ee262ba667bf5 225 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 17 223 1.3E-55 T 11-11-2016 IPR005744 Hly-III GO:0016021|GO:0019835 AUP74_RS05860 d33ece54ba0fcb172c6ee262ba667bf5 225 Pfam PF03006 Haemolysin-III related 14 216 3.1E-41 T 11-11-2016 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 AUP74_RS08445 545e20474c65677095545502582590ad 336 SUPERFAMILY SSF53955 31 328 4.5E-90 T 11-11-2016 IPR023346 Lysozyme-like domain AUP74_RS08445 545e20474c65677095545502582590ad 336 Gene3D G3DSA:1.10.530.10 78 134 7.7E-54 T 11-11-2016 AUP74_RS08445 545e20474c65677095545502582590ad 336 Gene3D G3DSA:1.10.530.10 216 330 7.7E-54 T 11-11-2016 AUP74_RS08445 545e20474c65677095545502582590ad 336 TIGRFAM TIGR02282 MltB: lytic murein transglycosylase B 38 328 1.9E-120 T 11-11-2016 IPR011757 Lytic transglycosylase MltB AUP74_RS08445 545e20474c65677095545502582590ad 336 Pfam PF13406 Transglycosylase SLT domain 34 326 1.6E-100 T 11-11-2016 IPR031304 Transglycosylase SLT domain 2 AUP74_RS16520 eea26a99781575d72aafd958e6624954 493 Gene3D G3DSA:3.40.190.10 157 212 4.6E-6 T 11-11-2016 AUP74_RS16520 eea26a99781575d72aafd958e6624954 493 Gene3D G3DSA:3.40.190.10 20 156 4.5E-26 T 11-11-2016 AUP74_RS16520 eea26a99781575d72aafd958e6624954 493 SUPERFAMILY SSF53955 436 452 2.25E-34 T 11-11-2016 IPR023346 Lysozyme-like domain AUP74_RS16520 eea26a99781575d72aafd958e6624954 493 SUPERFAMILY SSF53955 250 401 2.25E-34 T 11-11-2016 IPR023346 Lysozyme-like domain AUP74_RS16520 eea26a99781575d72aafd958e6624954 493 Gene3D G3DSA:1.10.530.10 278 398 9.8E-37 T 11-11-2016 AUP74_RS16520 eea26a99781575d72aafd958e6624954 493 Gene3D G3DSA:1.10.530.10 433 451 9.8E-37 T 11-11-2016 AUP74_RS16520 eea26a99781575d72aafd958e6624954 493 Hamap MF_02016 Membrane-bound lytic murein transglycosylase F [mltF]. 7 482 45.159 T 11-11-2016 IPR023703 Membrane-bound lytic murein transglycosylase F GO:0016837 AUP74_RS16520 eea26a99781575d72aafd958e6624954 493 Pfam PF01464 Transglycosylase SLT domain 298 399 4.9E-21 T 11-11-2016 IPR008258 Transglycosylase SLT domain 1 AUP74_RS16520 eea26a99781575d72aafd958e6624954 493 SUPERFAMILY SSF53850 45 270 1.54E-38 T 11-11-2016 AUP74_RS16520 eea26a99781575d72aafd958e6624954 493 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 49 270 9.8E-35 T 11-11-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AUP74_RS16520 eea26a99781575d72aafd958e6624954 493 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 314 342 - T 11-11-2016 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 AUP74_RS16520 eea26a99781575d72aafd958e6624954 493 SMART SM00062 44 271 2.5E-30 T 11-11-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AUP74_RS11480 0b5794e9806a384841fcf830a94778f3 369 Pfam PF06629 MltA-interacting protein MipA 149 369 9.0E-41 T 11-11-2016 IPR010583 MltA-interacting MipA AUP74_RS11480 0b5794e9806a384841fcf830a94778f3 369 Pfam PF09912 Uncharacterized protein conserved in bacteria (DUF2141) 34 129 7.7E-20 T 11-11-2016 IPR018673 Protein of unknown function DUF2141 AUP74_RS15730 deed437b963f7d2fd2dad4454ba79dd8 284 Pfam PF01479 S4 domain 11 55 1.1E-12 T 11-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 AUP74_RS15730 deed437b963f7d2fd2dad4454ba79dd8 284 SMART SM00363 10 67 8.5E-12 T 11-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 AUP74_RS15730 deed437b963f7d2fd2dad4454ba79dd8 284 Gene3D G3DSA:3.10.290.10 9 68 3.1E-20 T 11-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 AUP74_RS15730 deed437b963f7d2fd2dad4454ba79dd8 284 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 110 124 - T 11-11-2016 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 AUP74_RS15730 deed437b963f7d2fd2dad4454ba79dd8 284 SUPERFAMILY SSF55174 12 102 1.77E-16 T 11-11-2016 AUP74_RS15730 deed437b963f7d2fd2dad4454ba79dd8 284 Pfam PF00849 RNA pseudouridylate synthase 72 200 3.0E-15 T 11-11-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS15730 deed437b963f7d2fd2dad4454ba79dd8 284 SUPERFAMILY SSF55120 71 240 7.2E-43 T 11-11-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS15730 deed437b963f7d2fd2dad4454ba79dd8 284 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 76 236 1.0E-51 T 11-11-2016 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 AUP74_RS01400 de063fd5a02da43ed8dd8bad91f97c9a 482 Gene3D G3DSA:3.40.1160.10 134 316 6.6E-23 T 11-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase AUP74_RS01400 de063fd5a02da43ed8dd8bad91f97c9a 482 Gene3D G3DSA:3.40.1160.10 6 55 6.6E-23 T 11-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase AUP74_RS01400 de063fd5a02da43ed8dd8bad91f97c9a 482 Pfam PF00696 Amino acid kinase family 5 302 6.2E-25 T 11-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase AUP74_RS01400 de063fd5a02da43ed8dd8bad91f97c9a 482 Pfam PF13840 ACT domain 404 466 3.8E-9 T 11-11-2016 IPR027795 GATS-like ACT domain AUP74_RS01400 de063fd5a02da43ed8dd8bad91f97c9a 482 SUPERFAMILY SSF55021 407 474 1.21E-15 T 11-11-2016 AUP74_RS01400 de063fd5a02da43ed8dd8bad91f97c9a 482 SUPERFAMILY SSF53633 5 316 1.38E-53 T 11-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase AUP74_RS02675 cd8bc4ad03af96334d24af65ee675dea 266 Pfam PF13432 Tetratricopeptide repeat 94 142 0.0057 T 11-11-2016 AUP74_RS02675 cd8bc4ad03af96334d24af65ee675dea 266 SUPERFAMILY SSF48452 56 225 8.68E-12 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS02675 cd8bc4ad03af96334d24af65ee675dea 266 Gene3D G3DSA:1.25.40.10 51 226 1.8E-15 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS12025 4c64c707d5654a7eec881c4360012d65 420 Pfam PF02687 FtsX-like permease family 279 412 2.8E-18 T 11-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 AUP74_RS12025 4c64c707d5654a7eec881c4360012d65 420 Pfam PF12704 MacB-like periplasmic core domain 31 218 1.6E-14 T 11-11-2016 IPR025857 MacB-like periplasmic core domain AUP74_RS12025 4c64c707d5654a7eec881c4360012d65 420 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 5 419 7.0E-122 T 11-11-2016 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 AUP74_RS16195 06e6afebd52c5bb77e6ca1c185f09fa6 70 Pfam PF04324 BFD-like [2Fe-2S] binding domain 2 51 2.8E-12 T 11-11-2016 IPR007419 BFD-like [2Fe-2S]-binding domain AUP74_RS02410 e5d6451e6c00cb21dc6ecd803f88c5a2 224 SMART SM00702 25 211 3.0E-17 T 11-11-2016 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 AUP74_RS02410 e5d6451e6c00cb21dc6ecd803f88c5a2 224 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 114 211 1.8E-21 T 11-11-2016 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 AUP74_RS05980 32b6371a0eb5c265fa173b8df5fcba71 396 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 284 371 5.3E-10 T 11-11-2016 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 AUP74_RS05980 32b6371a0eb5c265fa173b8df5fcba71 396 PIRSF PIRSF038941 9 396 1.8E-170 T 11-11-2016 IPR005730 Carboxynorspermidine decarboxylase KEGG: 00330+4.1.1.96|MetaCyc: PWY-6562 AUP74_RS05980 32b6371a0eb5c265fa173b8df5fcba71 396 SUPERFAMILY SSF51419 26 263 3.2E-39 T 11-11-2016 IPR029066 PLP-binding barrel AUP74_RS05980 32b6371a0eb5c265fa173b8df5fcba71 396 SUPERFAMILY SSF50621 234 378 2.03E-30 T 11-11-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AUP74_RS05980 32b6371a0eb5c265fa173b8df5fcba71 396 Gene3D G3DSA:3.20.20.10 33 257 5.7E-18 T 11-11-2016 IPR029066 PLP-binding barrel AUP74_RS05980 32b6371a0eb5c265fa173b8df5fcba71 396 TIGRFAM TIGR01047 nspC: carboxynorspermidine decarboxylase 18 395 1.7E-148 T 11-11-2016 IPR005730 Carboxynorspermidine decarboxylase KEGG: 00330+4.1.1.96|MetaCyc: PWY-6562 AUP74_RS05980 32b6371a0eb5c265fa173b8df5fcba71 396 Gene3D G3DSA:2.40.37.10 258 374 2.0E-24 T 11-11-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AUP74_RS02785 fb738af02e7d19776c4fd51911827347 304 Gene3D G3DSA:3.40.50.1820 40 295 1.5E-54 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS02785 fb738af02e7d19776c4fd51911827347 304 Pfam PF00756 Putative esterase 41 290 3.2E-26 T 11-11-2016 IPR000801 Putative esterase Reactome: R-HSA-156590 AUP74_RS02785 fb738af02e7d19776c4fd51911827347 304 SUPERFAMILY SSF53474 40 295 3.81E-39 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS12665 31ee0152e91ee1d26c6a9df19d51340f 335 TIGRFAM TIGR03182 PDH_E1_alph_y: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 12 324 3.4E-133 T 11-11-2016 IPR017597 Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y GO:0004739|GO:0006086|GO:0043231 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 AUP74_RS12665 31ee0152e91ee1d26c6a9df19d51340f 335 SUPERFAMILY SSF52518 5 330 2.95E-93 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS12665 31ee0152e91ee1d26c6a9df19d51340f 335 Pfam PF00676 Dehydrogenase E1 component 19 309 1.3E-82 T 11-11-2016 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 AUP74_RS12665 31ee0152e91ee1d26c6a9df19d51340f 335 Gene3D G3DSA:3.40.50.970 4 327 2.8E-123 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS07145 0d1167b7705fd9bc64dc45ad580dc1a9 1016 SUPERFAMILY SSF53300 50 158 2.0E-14 T 11-11-2016 IPR002035 von Willebrand factor, type A AUP74_RS07145 0d1167b7705fd9bc64dc45ad580dc1a9 1016 SUPERFAMILY SSF53300 258 321 2.0E-14 T 11-11-2016 IPR002035 von Willebrand factor, type A AUP74_RS07145 0d1167b7705fd9bc64dc45ad580dc1a9 1016 SUPERFAMILY SSF53300 205 223 2.0E-14 T 11-11-2016 IPR002035 von Willebrand factor, type A AUP74_RS07145 0d1167b7705fd9bc64dc45ad580dc1a9 1016 SMART SM00327 48 315 1.5E-6 T 11-11-2016 IPR002035 von Willebrand factor, type A AUP74_RS07145 0d1167b7705fd9bc64dc45ad580dc1a9 1016 Pfam PF05567 Neisseria PilC beta-propeller domain 473 832 3.0E-58 T 11-11-2016 IPR008707 PilC beta-propeller domain AUP74_RS07145 0d1167b7705fd9bc64dc45ad580dc1a9 1016 Gene3D G3DSA:3.40.50.410 257 316 2.9E-6 T 11-11-2016 IPR002035 von Willebrand factor, type A AUP74_RS07145 0d1167b7705fd9bc64dc45ad580dc1a9 1016 Gene3D G3DSA:3.40.50.410 50 176 2.9E-6 T 11-11-2016 IPR002035 von Willebrand factor, type A AUP74_RS07145 0d1167b7705fd9bc64dc45ad580dc1a9 1016 Pfam PF13519 von Willebrand factor type A domain 51 147 3.2E-7 T 11-11-2016 IPR002035 von Willebrand factor, type A AUP74_RS16850 40e0688a27510583deab843e1e48de7c 208 Gene3D G3DSA:3.40.30.10 7 100 3.8E-29 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS16850 40e0688a27510583deab843e1e48de7c 208 SUPERFAMILY SSF47616 82 207 4.12E-24 T 11-11-2016 IPR010987 Glutathione S-transferase, C-terminal-like AUP74_RS16850 40e0688a27510583deab843e1e48de7c 208 Pfam PF13410 Glutathione S-transferase, C-terminal domain 127 189 1.3E-6 T 11-11-2016 AUP74_RS16850 40e0688a27510583deab843e1e48de7c 208 Pfam PF13417 Glutathione S-transferase, N-terminal domain 18 87 6.1E-16 T 11-11-2016 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 AUP74_RS16850 40e0688a27510583deab843e1e48de7c 208 Gene3D G3DSA:1.20.1050.10 101 207 4.8E-17 T 11-11-2016 IPR010987 Glutathione S-transferase, C-terminal-like AUP74_RS16850 40e0688a27510583deab843e1e48de7c 208 SUPERFAMILY SSF52833 10 110 1.72E-22 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS15580 fd4d2bcfec5a119689944db5782b1154 423 Gene3D G3DSA:3.30.465.10 320 421 1.9E-19 T 11-11-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 AUP74_RS15580 fd4d2bcfec5a119689944db5782b1154 423 SMART SM01091 344 422 1.9E-18 T 11-11-2016 IPR005170 Transporter-associated domain AUP74_RS15580 fd4d2bcfec5a119689944db5782b1154 423 Pfam PF03471 Transporter associated domain 346 420 2.4E-13 T 11-11-2016 IPR005170 Transporter-associated domain AUP74_RS15580 fd4d2bcfec5a119689944db5782b1154 423 SUPERFAMILY SSF56176 341 421 4.91E-18 T 11-11-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 AUP74_RS15580 fd4d2bcfec5a119689944db5782b1154 423 Gene3D G3DSA:3.10.580.10 194 319 7.4E-22 T 11-11-2016 AUP74_RS15580 fd4d2bcfec5a119689944db5782b1154 423 Pfam PF00571 CBS domain 205 261 7.5E-4 T 11-11-2016 IPR000644 CBS domain AUP74_RS15580 fd4d2bcfec5a119689944db5782b1154 423 Pfam PF00571 CBS domain 278 328 4.4E-6 T 11-11-2016 IPR000644 CBS domain AUP74_RS15580 fd4d2bcfec5a119689944db5782b1154 423 Pfam PF01595 Domain of unknown function DUF21 13 182 3.6E-46 T 11-11-2016 IPR002550 Domain of unknown function DUF21 AUP74_RS15580 fd4d2bcfec5a119689944db5782b1154 423 SUPERFAMILY SSF54631 193 331 5.94E-30 T 11-11-2016 AUP74_RS12175 578d1862051cf27ba7ff8405a192d69f 320 SUPERFAMILY SSF56935 27 320 3.66E-46 T 11-11-2016 AUP74_RS12175 578d1862051cf27ba7ff8405a192d69f 320 PRINTS PR00184 Neisseria sp. porin signature 94 113 3.5E-6 T 11-11-2016 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 AUP74_RS12175 578d1862051cf27ba7ff8405a192d69f 320 PRINTS PR00184 Neisseria sp. porin signature 150 167 3.5E-6 T 11-11-2016 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 AUP74_RS12175 578d1862051cf27ba7ff8405a192d69f 320 PRINTS PR00184 Neisseria sp. porin signature 188 205 3.5E-6 T 11-11-2016 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 AUP74_RS12175 578d1862051cf27ba7ff8405a192d69f 320 Gene3D G3DSA:2.40.160.10 27 309 8.9E-44 T 11-11-2016 IPR023614 Porin domain AUP74_RS12175 578d1862051cf27ba7ff8405a192d69f 320 Pfam PF13609 Gram-negative porin 8 298 3.8E-37 T 11-11-2016 AUP74_RS06710 5e5dcd14a9f9c9c1e12919b06b79127d 332 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 89 326 2.7E-55 T 11-11-2016 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AUP74_RS06710 5e5dcd14a9f9c9c1e12919b06b79127d 332 Gene3D G3DSA:3.30.930.10 84 277 3.1E-52 T 11-11-2016 AUP74_RS06710 5e5dcd14a9f9c9c1e12919b06b79127d 332 Gene3D G3DSA:2.30.30.100 280 328 4.5E-20 T 11-11-2016 AUP74_RS06710 5e5dcd14a9f9c9c1e12919b06b79127d 332 Gene3D G3DSA:1.10.10.10 11 64 1.2E-21 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS06710 5e5dcd14a9f9c9c1e12919b06b79127d 332 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 9 326 31.947 T 11-11-2016 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 AUP74_RS06710 5e5dcd14a9f9c9c1e12919b06b79127d 332 Pfam PF03099 Biotin/lipoate A/B protein ligase family 93 217 1.8E-11 T 11-11-2016 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 AUP74_RS06710 5e5dcd14a9f9c9c1e12919b06b79127d 332 Pfam PF08279 HTH domain 12 61 5.9E-13 T 11-11-2016 IPR013196 Helix-turn-helix, type 11 AUP74_RS06710 5e5dcd14a9f9c9c1e12919b06b79127d 332 Pfam PF02237 Biotin protein ligase C terminal domain 281 326 5.5E-7 T 11-11-2016 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AUP74_RS06710 5e5dcd14a9f9c9c1e12919b06b79127d 332 SUPERFAMILY SSF50037 280 326 7.78E-11 T 11-11-2016 IPR008988 Transcriptional repressor, C-terminal AUP74_RS06710 5e5dcd14a9f9c9c1e12919b06b79127d 332 SUPERFAMILY SSF55681 88 277 3.18E-50 T 11-11-2016 AUP74_RS06710 5e5dcd14a9f9c9c1e12919b06b79127d 332 SUPERFAMILY SSF46785 10 62 6.43E-12 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS14730 eadbb51e6baa01366fe988f25d37e833 166 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 78 161 8.0E-38 T 11-11-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 AUP74_RS14730 eadbb51e6baa01366fe988f25d37e833 166 SUPERFAMILY SSF55200 78 165 4.84E-33 T 11-11-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 AUP74_RS14730 eadbb51e6baa01366fe988f25d37e833 166 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 2 164 27.36 T 11-11-2016 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 AUP74_RS14730 eadbb51e6baa01366fe988f25d37e833 166 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 1 68 5.6E-28 T 11-11-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 AUP74_RS14730 eadbb51e6baa01366fe988f25d37e833 166 Gene3D G3DSA:3.30.110.10 73 165 6.1E-40 T 11-11-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 AUP74_RS14730 eadbb51e6baa01366fe988f25d37e833 166 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 1 164 3.1E-62 T 11-11-2016 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 AUP74_RS14730 eadbb51e6baa01366fe988f25d37e833 166 Gene3D G3DSA:3.10.20.80 1 72 8.6E-31 T 11-11-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 AUP74_RS14730 eadbb51e6baa01366fe988f25d37e833 166 SUPERFAMILY SSF54364 1 72 3.4E-25 T 11-11-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 AUP74_RS01960 dcd2028ded9b8fa8c983d5e305573da2 550 Gene3D G3DSA:2.60.40.1180 480 548 5.4E-6 T 11-11-2016 IPR013780 Glycosyl hydrolase, all-beta AUP74_RS01960 dcd2028ded9b8fa8c983d5e305573da2 550 SUPERFAMILY SSF51445 12 471 1.87E-128 T 11-11-2016 IPR017853 Glycoside hydrolase superfamily AUP74_RS01960 dcd2028ded9b8fa8c983d5e305573da2 550 SMART SM00642 21 411 3.4E-122 T 11-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AUP74_RS01960 dcd2028ded9b8fa8c983d5e305573da2 550 Pfam PF00128 Alpha amylase, catalytic domain 36 385 3.8E-92 T 11-11-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AUP74_RS01960 dcd2028ded9b8fa8c983d5e305573da2 550 SUPERFAMILY SSF51011 479 547 4.37E-5 T 11-11-2016 AUP74_RS01960 dcd2028ded9b8fa8c983d5e305573da2 550 Gene3D G3DSA:3.90.400.10 113 183 1.1E-28 T 11-11-2016 AUP74_RS01960 dcd2028ded9b8fa8c983d5e305573da2 550 Gene3D G3DSA:3.20.20.80 184 472 4.7E-102 T 11-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 AUP74_RS01960 dcd2028ded9b8fa8c983d5e305573da2 550 Gene3D G3DSA:3.20.20.80 11 112 4.7E-102 T 11-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 AUP74_RS05390 fd21711cd8630912b79de50161238594 333 Gene3D G3DSA:2.60.120.600 187 330 3.1E-29 T 11-11-2016 IPR010621 Domain of unknown function DUF1214 AUP74_RS05390 fd21711cd8630912b79de50161238594 333 Pfam PF06863 Protein of unknown function (DUF1254) 48 155 1.3E-11 T 11-11-2016 IPR010679 Domain of unknown function DUF1254 AUP74_RS05390 fd21711cd8630912b79de50161238594 333 SUPERFAMILY SSF160935 16 329 1.29E-71 T 11-11-2016 AUP74_RS05390 fd21711cd8630912b79de50161238594 333 Pfam PF06742 Protein of unknown function (DUF1214) 230 315 7.6E-15 T 11-11-2016 IPR010621 Domain of unknown function DUF1214 AUP74_RS13645 a33a52d1991002bb3542f2c1c57196fd 334 SMART SM00342 247 329 3.0E-21 T 11-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AUP74_RS13645 a33a52d1991002bb3542f2c1c57196fd 334 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 21 203 2.1E-33 T 11-11-2016 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal AUP74_RS13645 a33a52d1991002bb3542f2c1c57196fd 334 Pfam PF12833 Helix-turn-helix domain 253 330 7.1E-16 T 11-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AUP74_RS13645 a33a52d1991002bb3542f2c1c57196fd 334 SUPERFAMILY SSF46689 282 331 6.81E-11 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS13645 a33a52d1991002bb3542f2c1c57196fd 334 Gene3D G3DSA:1.10.10.60 282 330 7.3E-12 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS07660 7266a034f3860729b31e5446fd6e345a 355 Gene3D G3DSA:3.20.10.10 171 335 1.1E-54 T 11-11-2016 AUP74_RS07660 7266a034f3860729b31e5446fd6e345a 355 SUPERFAMILY SSF56752 19 347 2.09E-95 T 11-11-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 AUP74_RS07660 7266a034f3860729b31e5446fd6e345a 355 ProSitePatterns PS00770 Aminotransferases class-IV signature. 227 256 - T 11-11-2016 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 AUP74_RS07660 7266a034f3860729b31e5446fd6e345a 355 Pfam PF01063 Amino-transferase class IV 68 305 6.9E-32 T 11-11-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 AUP74_RS07660 7266a034f3860729b31e5446fd6e345a 355 Gene3D G3DSA:3.30.470.10 19 170 1.2E-56 T 11-11-2016 AUP74_RS07660 7266a034f3860729b31e5446fd6e345a 355 PIRSF PIRSF006468 6 351 9.1E-111 T 11-11-2016 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: R-HSA-70895 AUP74_RS07660 7266a034f3860729b31e5446fd6e345a 355 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 42 349 2.1E-104 T 11-11-2016 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: R-HSA-70895 AUP74_RS02035 4e1a9ddd718929b0ac76980c093a764f 494 Pfam PF00501 AMP-binding enzyme 12 381 1.7E-52 T 11-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 AUP74_RS02035 4e1a9ddd718929b0ac76980c093a764f 494 Gene3D G3DSA:3.30.300.30 380 475 3.6E-6 T 11-11-2016 AUP74_RS02035 4e1a9ddd718929b0ac76980c093a764f 494 SUPERFAMILY SSF56801 16 490 7.59E-86 T 11-11-2016 AUP74_RS02035 4e1a9ddd718929b0ac76980c093a764f 494 ProSitePatterns PS00455 Putative AMP-binding domain signature. 145 156 - T 11-11-2016 IPR020845 AMP-binding, conserved site AUP74_RS02035 4e1a9ddd718929b0ac76980c093a764f 494 Gene3D G3DSA:2.30.38.10 317 372 1.4E-7 T 11-11-2016 AUP74_RS02035 4e1a9ddd718929b0ac76980c093a764f 494 Gene3D G3DSA:3.40.50.980 154 316 1.1E-20 T 11-11-2016 AUP74_RS02035 4e1a9ddd718929b0ac76980c093a764f 494 Gene3D G3DSA:3.40.50.980 17 153 5.5E-21 T 11-11-2016 AUP74_RS05075 d5241a10edfc643560f1d9c57c2de3f5 461 Pfam PF00144 Beta-lactamase 165 433 1.9E-27 T 11-11-2016 IPR001466 Beta-lactamase-related AUP74_RS05075 d5241a10edfc643560f1d9c57c2de3f5 461 Gene3D G3DSA:3.40.710.10 142 437 1.4E-39 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS05075 d5241a10edfc643560f1d9c57c2de3f5 461 SUPERFAMILY SSF56601 128 439 5.79E-64 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS16140 eb02564d74de356e85837392f65a0a14 363 ProSitePatterns PS00789 Chorismate synthase signature 3. 319 335 - T 11-11-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AUP74_RS16140 eb02564d74de356e85837392f65a0a14 363 SUPERFAMILY SSF103263 4 351 5.76E-150 T 11-11-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AUP74_RS16140 eb02564d74de356e85837392f65a0a14 363 Pfam PF01264 Chorismate synthase 10 345 2.9E-140 T 11-11-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AUP74_RS16140 eb02564d74de356e85837392f65a0a14 363 Hamap MF_00300 Chorismate synthase [aroC]. 10 352 37.325 T 11-11-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AUP74_RS16140 eb02564d74de356e85837392f65a0a14 363 ProSitePatterns PS00788 Chorismate synthase signature 2. 124 140 - T 11-11-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AUP74_RS16140 eb02564d74de356e85837392f65a0a14 363 TIGRFAM TIGR00033 aroC: chorismate synthase 10 350 9.8E-141 T 11-11-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AUP74_RS16140 eb02564d74de356e85837392f65a0a14 363 PIRSF PIRSF001456 3 360 1.4E-141 T 11-11-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AUP74_RS16140 eb02564d74de356e85837392f65a0a14 363 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 11-11-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AUP74_RS16140 eb02564d74de356e85837392f65a0a14 363 Gene3D G3DSA:3.60.150.10 9 352 1.6E-158 T 11-11-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AUP74_RS08190 66f2585adc4bc26abdfef3027687e95c 500 SUPERFAMILY SSF69705 1 127 1.7E-38 T 11-11-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 AUP74_RS08190 66f2585adc4bc26abdfef3027687e95c 500 Gene3D G3DSA:2.40.50.140 130 200 2.0E-21 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS08190 66f2585adc4bc26abdfef3027687e95c 500 Pfam PF00575 S1 RNA binding domain 134 197 1.8E-6 T 11-11-2016 IPR003029 S1 domain GO:0003676 AUP74_RS08190 66f2585adc4bc26abdfef3027687e95c 500 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 344 2.0E-121 T 11-11-2016 IPR010213 Transcription termination factor NusA GO:0003723 AUP74_RS08190 66f2585adc4bc26abdfef3027687e95c 500 SUPERFAMILY SSF50249 134 201 3.98E-18 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS08190 66f2585adc4bc26abdfef3027687e95c 500 Gene3D G3DSA:1.10.150.20 431 495 6.3E-23 T 11-11-2016 AUP74_RS08190 66f2585adc4bc26abdfef3027687e95c 500 Gene3D G3DSA:1.10.150.20 356 422 1.2E-23 T 11-11-2016 AUP74_RS08190 66f2585adc4bc26abdfef3027687e95c 500 SUPERFAMILY SSF47794 356 419 1.3E-17 T 11-11-2016 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 AUP74_RS08190 66f2585adc4bc26abdfef3027687e95c 500 SUPERFAMILY SSF54814 281 345 2.81E-14 T 11-11-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 AUP74_RS08190 66f2585adc4bc26abdfef3027687e95c 500 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 442 491 3.8E-18 T 11-11-2016 IPR010214 Transcription termination factor NusA, C-terminal duplication AUP74_RS08190 66f2585adc4bc26abdfef3027687e95c 500 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 367 416 9.7E-20 T 11-11-2016 IPR010214 Transcription termination factor NusA, C-terminal duplication AUP74_RS08190 66f2585adc4bc26abdfef3027687e95c 500 Gene3D G3DSA:3.30.300.20 280 348 4.3E-27 T 11-11-2016 IPR015946 K homology domain-like, alpha/beta AUP74_RS08190 66f2585adc4bc26abdfef3027687e95c 500 Gene3D G3DSA:3.30.1480.10 1 126 2.3E-44 T 11-11-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 AUP74_RS08190 66f2585adc4bc26abdfef3027687e95c 500 SUPERFAMILY SSF54814 203 280 2.42E-29 T 11-11-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 AUP74_RS08190 66f2585adc4bc26abdfef3027687e95c 500 SMART SM00316 135 202 2.1E-11 T 11-11-2016 IPR022967 RNA-binding domain, S1 AUP74_RS08190 66f2585adc4bc26abdfef3027687e95c 500 Gene3D G3DSA:3.30.300.20 201 279 9.0E-33 T 11-11-2016 IPR015946 K homology domain-like, alpha/beta AUP74_RS08190 66f2585adc4bc26abdfef3027687e95c 500 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 412 29.35 T 11-11-2016 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 AUP74_RS08190 66f2585adc4bc26abdfef3027687e95c 500 SUPERFAMILY SSF47794 431 493 3.3E-16 T 11-11-2016 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 AUP74_RS08190 66f2585adc4bc26abdfef3027687e95c 500 Pfam PF13184 NusA-like KH domain 232 299 1.7E-26 T 11-11-2016 IPR025249 KH domain, NusA-like GO:0003723 AUP74_RS08190 66f2585adc4bc26abdfef3027687e95c 500 Pfam PF14520 Helix-hairpin-helix domain 434 489 4.8E-9 T 11-11-2016 AUP74_RS08190 66f2585adc4bc26abdfef3027687e95c 500 Pfam PF08529 NusA N-terminal domain 4 125 1.6E-36 T 11-11-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 AUP74_RS04385 1bcf9cde757ea79590e655c70a6ab8af 139 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 6 84 1.6E-29 T 11-11-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 AUP74_RS04385 1bcf9cde757ea79590e655c70a6ab8af 139 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 130 9.9E-41 T 11-11-2016 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 AUP74_RS04385 1bcf9cde757ea79590e655c70a6ab8af 139 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 3 129 20.228 T 11-11-2016 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 AUP74_RS04385 1bcf9cde757ea79590e655c70a6ab8af 139 Gene3D G3DSA:1.20.5.440 89 131 1.3E-10 T 11-11-2016 AUP74_RS04385 1bcf9cde757ea79590e655c70a6ab8af 139 SUPERFAMILY SSF46604 87 135 3.66E-9 T 11-11-2016 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210 AUP74_RS04385 1bcf9cde757ea79590e655c70a6ab8af 139 SUPERFAMILY SSF51344 3 86 2.75E-25 T 11-11-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 AUP74_RS04385 1bcf9cde757ea79590e655c70a6ab8af 139 Gene3D G3DSA:2.60.15.10 3 87 4.9E-29 T 11-11-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 AUP74_RS04385 1bcf9cde757ea79590e655c70a6ab8af 139 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 10 86 2.0E-26 T 11-11-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 AUP74_RS04385 1bcf9cde757ea79590e655c70a6ab8af 139 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 86 129 2.5E-9 T 11-11-2016 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210 AUP74_RS11765 13515aa6eef0a0c0b43b3aa260efabe1 183 Pfam PF14316 Domain of unknown function (DUF4381) 17 160 6.5E-41 T 11-11-2016 IPR025489 Protein of unknown function (DUF4381 AUP74_RS08640 eb274d311508291b1414582bb3fe83d4 480 Gene3D G3DSA:3.90.1300.10 2 461 5.0E-127 T 11-11-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AUP74_RS08640 eb274d311508291b1414582bb3fe83d4 480 SUPERFAMILY SSF75304 3 464 9.68E-128 T 11-11-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AUP74_RS08640 eb274d311508291b1414582bb3fe83d4 480 Pfam PF01425 Amidase 25 450 1.8E-99 T 11-11-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AUP74_RS13940 f9f1e654304c581802aae52b9d89e6c5 474 Pfam PF01565 FAD binding domain 42 179 1.1E-35 T 11-11-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AUP74_RS13940 f9f1e654304c581802aae52b9d89e6c5 474 Gene3D G3DSA:1.10.45.10 417 456 1.6E-5 T 11-11-2016 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 AUP74_RS13940 f9f1e654304c581802aae52b9d89e6c5 474 SUPERFAMILY SSF56176 4 216 1.54E-64 T 11-11-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 AUP74_RS13940 f9f1e654304c581802aae52b9d89e6c5 474 Gene3D G3DSA:3.30.43.10 4 95 1.2E-21 T 11-11-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 AUP74_RS13940 f9f1e654304c581802aae52b9d89e6c5 474 Gene3D G3DSA:3.30.465.10 96 216 2.4E-34 T 11-11-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 AUP74_RS13940 f9f1e654304c581802aae52b9d89e6c5 474 SUPERFAMILY SSF55103 219 466 1.32E-63 T 11-11-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 AUP74_RS13940 f9f1e654304c581802aae52b9d89e6c5 474 Pfam PF02913 FAD linked oxidases, C-terminal domain 216 455 1.1E-59 T 11-11-2016 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 AUP74_RS03075 57b1b8b669f4470f3a1eac38280629e3 140 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 4 137 1.1E-52 T 11-11-2016 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 AUP74_RS03075 57b1b8b669f4470f3a1eac38280629e3 140 Pfam PF02566 OsmC-like protein 40 136 3.9E-17 T 11-11-2016 IPR003718 OsmC/Ohr family AUP74_RS03075 57b1b8b669f4470f3a1eac38280629e3 140 Gene3D G3DSA:3.30.300.20 45 139 1.5E-33 T 11-11-2016 IPR015946 K homology domain-like, alpha/beta AUP74_RS03075 57b1b8b669f4470f3a1eac38280629e3 140 Gene3D G3DSA:2.20.25.10 2 44 2.2E-20 T 11-11-2016 AUP74_RS03075 57b1b8b669f4470f3a1eac38280629e3 140 SUPERFAMILY SSF82784 2 138 1.31E-42 T 11-11-2016 IPR003718 OsmC/Ohr family AUP74_RS13835 75caa77650c3d3ba1dcf6a67bb7a899f 388 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 48 377 3.3E-65 T 11-11-2016 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 AUP74_RS13835 75caa77650c3d3ba1dcf6a67bb7a899f 388 Gene3D G3DSA:3.20.20.140 40 381 1.1E-84 T 11-11-2016 AUP74_RS13835 75caa77650c3d3ba1dcf6a67bb7a899f 388 SUPERFAMILY SSF51556 41 381 5.52E-72 T 11-11-2016 IPR032466 Metal-dependent hydrolase AUP74_RS11050 e33b3fda6fd25a683f0fe5eb1524326c 446 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 130 146 4.0E-28 T 11-11-2016 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 AUP74_RS11050 e33b3fda6fd25a683f0fe5eb1524326c 446 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 74 89 4.0E-28 T 11-11-2016 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 AUP74_RS11050 e33b3fda6fd25a683f0fe5eb1524326c 446 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 294 321 4.0E-28 T 11-11-2016 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 AUP74_RS11050 e33b3fda6fd25a683f0fe5eb1524326c 446 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 50 68 4.0E-28 T 11-11-2016 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 AUP74_RS11050 e33b3fda6fd25a683f0fe5eb1524326c 446 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 184 199 4.0E-28 T 11-11-2016 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 AUP74_RS11050 e33b3fda6fd25a683f0fe5eb1524326c 446 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 2 18 4.0E-28 T 11-11-2016 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 AUP74_RS11050 e33b3fda6fd25a683f0fe5eb1524326c 446 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 114 130 4.0E-28 T 11-11-2016 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 AUP74_RS11050 e33b3fda6fd25a683f0fe5eb1524326c 446 Gene3D G3DSA:3.50.50.60 4 179 1.3E-43 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS11050 e33b3fda6fd25a683f0fe5eb1524326c 446 Pfam PF00743 Flavin-binding monooxygenase-like 2 385 6.3E-57 T 11-11-2016 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 AUP74_RS11050 e33b3fda6fd25a683f0fe5eb1524326c 446 SUPERFAMILY SSF51905 171 216 6.29E-10 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS11050 e33b3fda6fd25a683f0fe5eb1524326c 446 SUPERFAMILY SSF51905 261 373 6.29E-10 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS11050 e33b3fda6fd25a683f0fe5eb1524326c 446 SUPERFAMILY SSF51905 2 203 5.76E-44 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS11050 e33b3fda6fd25a683f0fe5eb1524326c 446 Gene3D G3DSA:3.50.50.60 270 298 9.7E-7 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS11050 e33b3fda6fd25a683f0fe5eb1524326c 446 Gene3D G3DSA:3.50.50.60 180 238 9.7E-7 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS11050 e33b3fda6fd25a683f0fe5eb1524326c 446 Gene3D G3DSA:3.50.50.60 299 402 3.6E-13 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS11050 e33b3fda6fd25a683f0fe5eb1524326c 446 PIRSF PIRSF000332 1 391 2.2E-65 T 11-11-2016 IPR012143 Dimethylaniline monooxygenase, N-oxide-forming GO:0004499|GO:0050660|GO:0050661|GO:0055114 KEGG: 00982+1.14.13.8 AUP74_RS16260 ed41469d2723b4c80f8afe6d0f293237 543 Gene3D G3DSA:3.40.50.10490 286 499 5.2E-123 T 11-11-2016 AUP74_RS16260 ed41469d2723b4c80f8afe6d0f293237 543 Gene3D G3DSA:3.40.50.10490 11 95 5.2E-123 T 11-11-2016 AUP74_RS16260 ed41469d2723b4c80f8afe6d0f293237 543 Gene3D G3DSA:1.10.1390.10 500 541 1.9E-17 T 11-11-2016 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS16260 ed41469d2723b4c80f8afe6d0f293237 543 Gene3D G3DSA:3.40.50.10490 105 283 1.5E-68 T 11-11-2016 AUP74_RS16260 ed41469d2723b4c80f8afe6d0f293237 543 Pfam PF00342 Phosphoglucose isomerase 49 534 4.0E-185 T 11-11-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS16260 ed41469d2723b4c80f8afe6d0f293237 543 PRINTS PR00662 Glucose-6-phosphate isomerase signature 331 352 3.3E-49 T 11-11-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS16260 ed41469d2723b4c80f8afe6d0f293237 543 PRINTS PR00662 Glucose-6-phosphate isomerase signature 476 490 3.3E-49 T 11-11-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS16260 ed41469d2723b4c80f8afe6d0f293237 543 PRINTS PR00662 Glucose-6-phosphate isomerase signature 142 161 3.3E-49 T 11-11-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS16260 ed41469d2723b4c80f8afe6d0f293237 543 PRINTS PR00662 Glucose-6-phosphate isomerase signature 458 476 3.3E-49 T 11-11-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS16260 ed41469d2723b4c80f8afe6d0f293237 543 PRINTS PR00662 Glucose-6-phosphate isomerase signature 490 503 3.3E-49 T 11-11-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS16260 ed41469d2723b4c80f8afe6d0f293237 543 PRINTS PR00662 Glucose-6-phosphate isomerase signature 254 272 3.3E-49 T 11-11-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS16260 ed41469d2723b4c80f8afe6d0f293237 543 SUPERFAMILY SSF53697 17 542 1.11E-190 T 11-11-2016 AUP74_RS16260 ed41469d2723b4c80f8afe6d0f293237 543 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 258 271 - T 11-11-2016 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS16260 ed41469d2723b4c80f8afe6d0f293237 543 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 43 517 38.557 T 11-11-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS13055 5ed7e3e2e11e881ab59445f5f38dd8cc 413 SUPERFAMILY SSF53901 214 412 1.34E-70 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS13055 5ed7e3e2e11e881ab59445f5f38dd8cc 413 PIRSF PIRSF000447 1 413 2.5E-188 T 11-11-2016 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 AUP74_RS13055 5ed7e3e2e11e881ab59445f5f38dd8cc 413 SUPERFAMILY SSF53901 4 252 3.57E-80 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS13055 5ed7e3e2e11e881ab59445f5f38dd8cc 413 SMART SM00825 Beta-ketoacyl synthase 6 413 1.3E-16 T 11-11-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain AUP74_RS13055 5ed7e3e2e11e881ab59445f5f38dd8cc 413 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 4 411 1.7E-195 T 11-11-2016 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 AUP74_RS13055 5ed7e3e2e11e881ab59445f5f38dd8cc 413 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 247 2.6E-62 T 11-11-2016 IPR014030 Beta-ketoacyl synthase, N-terminal AUP74_RS13055 5ed7e3e2e11e881ab59445f5f38dd8cc 413 Gene3D G3DSA:3.40.47.10 263 412 6.7E-62 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS13055 5ed7e3e2e11e881ab59445f5f38dd8cc 413 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 255 369 3.9E-38 T 11-11-2016 IPR014031 Beta-ketoacyl synthase, C-terminal AUP74_RS13055 5ed7e3e2e11e881ab59445f5f38dd8cc 413 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 155 171 - T 11-11-2016 IPR018201 Beta-ketoacyl synthase, active site AUP74_RS13055 5ed7e3e2e11e881ab59445f5f38dd8cc 413 Gene3D G3DSA:3.40.47.10 3 257 1.5E-78 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS11475 bc0859ba9e0764115dd102768af29e0a 339 SUPERFAMILY SSF111369 43 260 4.97E-40 T 11-11-2016 AUP74_RS11475 bc0859ba9e0764115dd102768af29e0a 339 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 54 253 1.6E-25 T 11-11-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AUP74_RS11475 bc0859ba9e0764115dd102768af29e0a 339 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 30 334 1.6E-75 T 11-11-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 AUP74_RS11475 bc0859ba9e0764115dd102768af29e0a 339 Gene3D G3DSA:2.40.50.100 149 180 7.7E-16 T 11-11-2016 AUP74_RS11475 bc0859ba9e0764115dd102768af29e0a 339 Gene3D G3DSA:2.40.50.100 55 88 7.7E-16 T 11-11-2016 AUP74_RS04495 a182b29c1b9465f148136e0a087eb65b 103 SUPERFAMILY SSF55729 15 83 6.49E-9 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS04495 a182b29c1b9465f148136e0a087eb65b 103 Gene3D G3DSA:3.40.630.30 15 94 7.7E-9 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS04495 a182b29c1b9465f148136e0a087eb65b 103 Pfam PF13673 Acetyltransferase (GNAT) domain 9 93 5.3E-6 T 11-11-2016 IPR000182 GNAT domain GO:0008080 AUP74_RS06635 e7a6ce0e77d018a1a28afd7401880ee6 117 Hamap MF_01380 Iron-sulfur cluster insertion protein ErpA [erpA]. 1 117 35.999 T 11-11-2016 IPR023063 FeS cluster insertion protein ErpA GO:0016226 AUP74_RS06635 e7a6ce0e77d018a1a28afd7401880ee6 117 SUPERFAMILY SSF89360 11 103 4.71E-30 T 11-11-2016 IPR000361 FeS cluster biogenesis AUP74_RS06635 e7a6ce0e77d018a1a28afd7401880ee6 117 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 12 116 9.6E-38 T 11-11-2016 IPR016092 FeS cluster insertion protein GO:0005198|GO:0016226|GO:0051536 AUP74_RS06635 e7a6ce0e77d018a1a28afd7401880ee6 117 Gene3D G3DSA:2.60.300.12 9 103 4.0E-32 T 11-11-2016 IPR000361 FeS cluster biogenesis AUP74_RS06635 e7a6ce0e77d018a1a28afd7401880ee6 117 Pfam PF01521 Iron-sulphur cluster biosynthesis 12 112 8.3E-18 T 11-11-2016 IPR000361 FeS cluster biogenesis AUP74_RS06635 e7a6ce0e77d018a1a28afd7401880ee6 117 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 98 115 - T 11-11-2016 IPR017870 FeS cluster insertion, C-terminal, conserved site AUP74_RS16765 252c113ab2e63c8d55fb8d7f489f1c95 587 Pfam PF03717 Penicillin-binding Protein dimerisation domain 66 215 9.5E-21 T 11-11-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 AUP74_RS16765 252c113ab2e63c8d55fb8d7f489f1c95 587 Pfam PF00905 Penicillin binding protein transpeptidase domain 256 556 3.4E-72 T 11-11-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 AUP74_RS16765 252c113ab2e63c8d55fb8d7f489f1c95 587 SUPERFAMILY SSF56601 231 564 1.46E-90 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS16765 252c113ab2e63c8d55fb8d7f489f1c95 587 Gene3D G3DSA:3.90.1310.10 138 237 3.9E-29 T 11-11-2016 AUP74_RS16765 252c113ab2e63c8d55fb8d7f489f1c95 587 Gene3D G3DSA:3.40.710.10 238 564 1.8E-87 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS16765 252c113ab2e63c8d55fb8d7f489f1c95 587 SUPERFAMILY SSF56519 61 230 1.18E-43 T 11-11-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 AUP74_RS02470 80199484cf41abec238edbac3a8ab355 181 Gene3D G3DSA:3.40.50.10420 1 180 9.9E-48 T 11-11-2016 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain AUP74_RS02470 80199484cf41abec238edbac3a8ab355 181 PIRSF PIRSF006806 1 177 1.1E-30 T 11-11-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase AUP74_RS02470 80199484cf41abec238edbac3a8ab355 181 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 1 174 3.0E-40 T 11-11-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase AUP74_RS02470 80199484cf41abec238edbac3a8ab355 181 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 2 174 7.9E-35 T 11-11-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase AUP74_RS02470 80199484cf41abec238edbac3a8ab355 181 SUPERFAMILY SSF100950 1 180 6.98E-48 T 11-11-2016 AUP74_RS07790 344109bba57430b682c80fcc6684be73 680 PRINTS PR01041 Methionyl-tRNA synthetase signature 45 59 2.8E-23 T 11-11-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AUP74_RS07790 344109bba57430b682c80fcc6684be73 680 PRINTS PR01041 Methionyl-tRNA synthetase signature 386 397 2.8E-23 T 11-11-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AUP74_RS07790 344109bba57430b682c80fcc6684be73 680 PRINTS PR01041 Methionyl-tRNA synthetase signature 13 26 2.8E-23 T 11-11-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AUP74_RS07790 344109bba57430b682c80fcc6684be73 680 PRINTS PR01041 Methionyl-tRNA synthetase signature 293 308 2.8E-23 T 11-11-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AUP74_RS07790 344109bba57430b682c80fcc6684be73 680 PRINTS PR01041 Methionyl-tRNA synthetase signature 254 265 2.8E-23 T 11-11-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AUP74_RS07790 344109bba57430b682c80fcc6684be73 680 PRINTS PR01041 Methionyl-tRNA synthetase signature 93 104 2.8E-23 T 11-11-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AUP74_RS07790 344109bba57430b682c80fcc6684be73 680 Pfam PF09334 tRNA synthetases class I (M) 11 398 1.4E-154 T 11-11-2016 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS07790 344109bba57430b682c80fcc6684be73 680 SUPERFAMILY SSF52374 9 144 7.74E-99 T 11-11-2016 AUP74_RS07790 344109bba57430b682c80fcc6684be73 680 SUPERFAMILY SSF52374 179 389 7.74E-99 T 11-11-2016 AUP74_RS07790 344109bba57430b682c80fcc6684be73 680 SUPERFAMILY SSF47323 392 547 3.92E-41 T 11-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS07790 344109bba57430b682c80fcc6684be73 680 Gene3D G3DSA:1.10.730.10 382 535 2.8E-38 T 11-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS07790 344109bba57430b682c80fcc6684be73 680 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 11 536 9.0E-177 T 11-11-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AUP74_RS07790 344109bba57430b682c80fcc6684be73 680 Gene3D G3DSA:2.40.50.140 572 679 3.9E-42 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS07790 344109bba57430b682c80fcc6684be73 680 SUPERFAMILY SSF50249 575 679 4.65E-31 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS07790 344109bba57430b682c80fcc6684be73 680 Gene3D G3DSA:2.20.28.20 148 179 1.8E-18 T 11-11-2016 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AUP74_RS07790 344109bba57430b682c80fcc6684be73 680 Pfam PF01588 Putative tRNA binding domain 585 677 9.3E-23 T 11-11-2016 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 AUP74_RS07790 344109bba57430b682c80fcc6684be73 680 SUPERFAMILY SSF57770 145 179 1.83E-12 T 11-11-2016 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AUP74_RS07790 344109bba57430b682c80fcc6684be73 680 Hamap MF_00098 Methionine--tRNA ligase [metG]. 9 546 39.743 T 11-11-2016 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AUP74_RS07790 344109bba57430b682c80fcc6684be73 680 Gene3D G3DSA:3.40.50.620 186 381 3.0E-85 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS07790 344109bba57430b682c80fcc6684be73 680 Gene3D G3DSA:3.40.50.620 9 147 3.0E-85 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS07790 344109bba57430b682c80fcc6684be73 680 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 18 29 - T 11-11-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS07790 344109bba57430b682c80fcc6684be73 680 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 545 679 4.1E-45 T 11-11-2016 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AUP74_RS11880 6ba5f9c67eb34fdf8270fcbf1821425b 333 Gene3D G3DSA:3.20.20.300 1 286 1.7E-86 T 11-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AUP74_RS11880 6ba5f9c67eb34fdf8270fcbf1821425b 333 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 227 244 - T 11-11-2016 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 AUP74_RS11880 6ba5f9c67eb34fdf8270fcbf1821425b 333 SUPERFAMILY SSF51445 1 287 2.74E-75 T 11-11-2016 IPR017853 Glycoside hydrolase superfamily AUP74_RS11880 6ba5f9c67eb34fdf8270fcbf1821425b 333 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 3 285 1.1E-75 T 11-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AUP74_RS11880 6ba5f9c67eb34fdf8270fcbf1821425b 333 Hamap MF_00364 Beta-hexosaminidase [nagZ]. 1 331 46.675 T 11-11-2016 IPR022956 Beta-hexosaminidase, bacterial GO:0004563 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 AUP74_RS00630 3adc2da604531e502ba522865527536c 373 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 355 1.6E-129 T 11-11-2016 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 AUP74_RS00630 3adc2da604531e502ba522865527536c 373 Gene3D G3DSA:3.40.50.300 15 166 4.1E-68 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS00630 3adc2da604531e502ba522865527536c 373 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 124 142 5.9E-6 T 11-11-2016 IPR001270 ClpA/B family GO:0005524 AUP74_RS00630 3adc2da604531e502ba522865527536c 373 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 41 59 5.9E-6 T 11-11-2016 IPR001270 ClpA/B family GO:0005524 AUP74_RS00630 3adc2da604531e502ba522865527536c 373 SUPERFAMILY SSF48019 244 363 3.91E-28 T 11-11-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 AUP74_RS00630 3adc2da604531e502ba522865527536c 373 Pfam PF13177 DNA polymerase III, delta subunit 20 178 3.5E-44 T 11-11-2016 AUP74_RS00630 3adc2da604531e502ba522865527536c 373 SUPERFAMILY SSF52540 29 221 7.04E-57 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS00630 3adc2da604531e502ba522865527536c 373 Gene3D G3DSA:1.10.8.60 167 242 4.8E-30 T 11-11-2016 AUP74_RS00630 3adc2da604531e502ba522865527536c 373 SMART SM00382 37 179 7.4E-7 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS00630 3adc2da604531e502ba522865527536c 373 Gene3D G3DSA:1.20.272.10 243 360 2.8E-41 T 11-11-2016 AUP74_RS00630 3adc2da604531e502ba522865527536c 373 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 233 358 1.7E-28 T 11-11-2016 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 AUP74_RS00155 b6285a063fafdc02c77f7b3ff7b7df81 277 Gene3D G3DSA:1.10.8.10 14 84 4.1E-27 T 11-11-2016 AUP74_RS00155 b6285a063fafdc02c77f7b3ff7b7df81 277 Gene3D G3DSA:3.40.50.150 87 275 5.8E-68 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS00155 b6285a063fafdc02c77f7b3ff7b7df81 277 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 18 276 3.6E-78 T 11-11-2016 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 AUP74_RS00155 b6285a063fafdc02c77f7b3ff7b7df81 277 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 1 275 44.712 T 11-11-2016 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 AUP74_RS00155 b6285a063fafdc02c77f7b3ff7b7df81 277 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 180 186 - T 11-11-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 AUP74_RS00155 b6285a063fafdc02c77f7b3ff7b7df81 277 Pfam PF13847 Methyltransferase domain 112 241 6.7E-18 T 11-11-2016 IPR025714 Methyltransferase domain AUP74_RS00155 b6285a063fafdc02c77f7b3ff7b7df81 277 SUPERFAMILY SSF53335 14 273 1.36E-60 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS00155 b6285a063fafdc02c77f7b3ff7b7df81 277 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 23 271 1.5E-91 T 11-11-2016 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 AUP74_RS16535 275cff4ccbbf3d1bc6da4ab14532bce6 127 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 124 2.5E-18 T 11-11-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AUP74_RS16535 275cff4ccbbf3d1bc6da4ab14532bce6 127 SUPERFAMILY SSF54593 1 126 2.01E-30 T 11-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AUP74_RS16535 275cff4ccbbf3d1bc6da4ab14532bce6 127 Gene3D G3DSA:3.10.180.10 7 126 5.4E-33 T 11-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AUP74_RS01410 8e71beb2497cb7ac9c6a3690b28fcf24 442 Pfam PF00202 Aminotransferase class-III 18 410 3.8E-83 T 11-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AUP74_RS01410 8e71beb2497cb7ac9c6a3690b28fcf24 442 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 232 268 - T 11-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AUP74_RS01410 8e71beb2497cb7ac9c6a3690b28fcf24 442 Gene3D G3DSA:3.40.640.10 56 312 7.5E-64 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AUP74_RS01410 8e71beb2497cb7ac9c6a3690b28fcf24 442 SUPERFAMILY SSF53383 10 412 6.26E-106 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase AUP74_RS01410 8e71beb2497cb7ac9c6a3690b28fcf24 442 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 2 417 1.4E-150 T 11-11-2016 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761 AUP74_RS01410 8e71beb2497cb7ac9c6a3690b28fcf24 442 TIGRFAM TIGR02407 ectoine_ectB: diaminobutyrate--2-oxoglutarate aminotransferase 2 412 5.1E-203 T 11-11-2016 IPR012773 Ectoine biosynthetic protein GO:0019491|GO:0030170|GO:0047307 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761 AUP74_RS01410 8e71beb2497cb7ac9c6a3690b28fcf24 442 Gene3D G3DSA:3.90.1150.10 12 54 1.2E-29 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS01410 8e71beb2497cb7ac9c6a3690b28fcf24 442 Gene3D G3DSA:3.90.1150.10 317 413 1.2E-29 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS07370 2f2b0a89d4bc9e013af4d2f87aa41be4 469 SUPERFAMILY SSF53187 204 451 7.07E-60 T 11-11-2016 AUP74_RS07370 2f2b0a89d4bc9e013af4d2f87aa41be4 469 Pfam PF04389 Peptidase family M28 262 446 1.3E-33 T 11-11-2016 IPR007484 Peptidase M28 AUP74_RS07370 2f2b0a89d4bc9e013af4d2f87aa41be4 469 Gene3D G3DSA:3.40.630.10 261 451 1.2E-64 T 11-11-2016 AUP74_RS07370 2f2b0a89d4bc9e013af4d2f87aa41be4 469 Gene3D G3DSA:3.40.630.10 44 100 1.2E-64 T 11-11-2016 AUP74_RS06185 f8bb445ecacce7850002c54a295fc06b 593 Gene3D G3DSA:1.20.140.10 270 458 1.4E-51 T 11-11-2016 AUP74_RS06185 f8bb445ecacce7850002c54a295fc06b 593 Gene3D G3DSA:1.10.540.10 38 160 3.5E-17 T 11-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 AUP74_RS06185 f8bb445ecacce7850002c54a295fc06b 593 Gene3D G3DSA:2.40.110.10 162 269 1.7E-27 T 11-11-2016 AUP74_RS06185 f8bb445ecacce7850002c54a295fc06b 593 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 38 158 4.6E-13 T 11-11-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 AUP74_RS06185 f8bb445ecacce7850002c54a295fc06b 593 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 4 31 1.9E-9 T 11-11-2016 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria AUP74_RS06185 f8bb445ecacce7850002c54a295fc06b 593 SUPERFAMILY SSF47203 289 459 1.77E-47 T 11-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AUP74_RS06185 f8bb445ecacce7850002c54a295fc06b 593 SUPERFAMILY SSF56645 38 281 2.62E-58 T 11-11-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 AUP74_RS06185 f8bb445ecacce7850002c54a295fc06b 593 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 467 588 1.3E-35 T 11-11-2016 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain AUP74_RS06185 f8bb445ecacce7850002c54a295fc06b 593 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 163 273 1.0E-16 T 11-11-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 AUP74_RS06185 f8bb445ecacce7850002c54a295fc06b 593 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 283 451 3.4E-20 T 11-11-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AUP74_RS07085 a903b78d4139f6c70d2cecf5b85221ad 176 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 107 122 6.1E-18 T 11-11-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 AUP74_RS07085 a903b78d4139f6c70d2cecf5b85221ad 176 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 59 67 6.1E-18 T 11-11-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 AUP74_RS07085 a903b78d4139f6c70d2cecf5b85221ad 176 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 143 159 6.1E-18 T 11-11-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 AUP74_RS07085 a903b78d4139f6c70d2cecf5b85221ad 176 Pfam PF01252 Signal peptidase (SPase) II 21 163 3.7E-39 T 11-11-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 AUP74_RS07085 a903b78d4139f6c70d2cecf5b85221ad 176 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 12 168 16.969 T 11-11-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 AUP74_RS07085 a903b78d4139f6c70d2cecf5b85221ad 176 TIGRFAM TIGR00077 lspA: signal peptidase II 14 168 3.0E-40 T 11-11-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 AUP74_RS16405 d8cc5088594444b844a7e467dd16061e 278 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 11-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AUP74_RS16405 d8cc5088594444b844a7e467dd16061e 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 3.0E-20 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS16405 d8cc5088594444b844a7e467dd16061e 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 3.0E-20 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS16405 d8cc5088594444b844a7e467dd16061e 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 3.0E-20 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS16405 d8cc5088594444b844a7e467dd16061e 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 3.0E-20 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS16405 d8cc5088594444b844a7e467dd16061e 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 3.0E-20 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS16405 d8cc5088594444b844a7e467dd16061e 278 Gene3D G3DSA:3.40.50.720 8 214 1.9E-48 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS16405 d8cc5088594444b844a7e467dd16061e 278 Pfam PF00106 short chain dehydrogenase 11 199 9.1E-39 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS16405 d8cc5088594444b844a7e467dd16061e 278 SUPERFAMILY SSF51735 9 257 8.96E-50 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS11720 67e8277d875b3add4fbfa0dcd55d072f 402 SUPERFAMILY SSF53756 1 390 5.38E-59 T 11-11-2016 AUP74_RS11720 67e8277d875b3add4fbfa0dcd55d072f 402 Gene3D G3DSA:3.40.50.2000 211 355 8.6E-22 T 11-11-2016 AUP74_RS11720 67e8277d875b3add4fbfa0dcd55d072f 402 Pfam PF00534 Glycosyl transferases group 1 207 363 5.5E-28 T 11-11-2016 IPR001296 Glycosyl transferase, family 1 AUP74_RS11720 67e8277d875b3add4fbfa0dcd55d072f 402 Pfam PF13439 Glycosyltransferase Family 4 15 191 1.4E-10 T 11-11-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AUP74_RS02310 650607bbc1bb15f2edf7babdde2d8443 443 Gene3D G3DSA:1.25.40.10 155 265 5.4E-11 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS02310 650607bbc1bb15f2edf7babdde2d8443 443 SMART SM00028 141 174 340.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS02310 650607bbc1bb15f2edf7babdde2d8443 443 SMART SM00028 176 209 0.53 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS02310 650607bbc1bb15f2edf7babdde2d8443 443 SMART SM00028 101 134 0.039 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS02310 650607bbc1bb15f2edf7babdde2d8443 443 SMART SM00028 352 385 94.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS02310 650607bbc1bb15f2edf7babdde2d8443 443 SMART SM00028 388 421 20.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS02310 650607bbc1bb15f2edf7babdde2d8443 443 Gene3D G3DSA:1.25.40.10 100 154 1.2E-6 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS02310 650607bbc1bb15f2edf7babdde2d8443 443 Gene3D G3DSA:1.25.40.10 321 421 3.1E-11 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS02310 650607bbc1bb15f2edf7babdde2d8443 443 SUPERFAMILY SSF48452 323 427 5.22E-11 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS02310 650607bbc1bb15f2edf7babdde2d8443 443 Pfam PF13181 Tetratricopeptide repeat 101 128 0.03 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS02310 650607bbc1bb15f2edf7babdde2d8443 443 Pfam PF13181 Tetratricopeptide repeat 389 416 0.014 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS02310 650607bbc1bb15f2edf7babdde2d8443 443 SUPERFAMILY SSF48452 77 258 1.45E-12 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS03110 e97c5d7a6e12658283337dc4720e2b38 206 SMART SM00421 143 200 4.6E-21 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS03110 e97c5d7a6e12658283337dc4720e2b38 206 SUPERFAMILY SSF46894 142 202 1.08E-15 T 11-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AUP74_RS03110 e97c5d7a6e12658283337dc4720e2b38 206 Gene3D G3DSA:1.10.10.10 133 201 1.1E-22 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS03110 e97c5d7a6e12658283337dc4720e2b38 206 SUPERFAMILY SSF52172 3 161 2.96E-26 T 11-11-2016 IPR011006 CheY-like superfamily AUP74_RS03110 e97c5d7a6e12658283337dc4720e2b38 206 Pfam PF00072 Response regulator receiver domain 6 116 5.0E-22 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS03110 e97c5d7a6e12658283337dc4720e2b38 206 SMART SM00448 3 116 9.0E-17 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS03110 e97c5d7a6e12658283337dc4720e2b38 206 ProSitePatterns PS00622 LuxR-type HTH domain signature. 160 187 - T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS03110 e97c5d7a6e12658283337dc4720e2b38 206 Pfam PF00196 Bacterial regulatory proteins, luxR family 145 200 1.2E-16 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS03110 e97c5d7a6e12658283337dc4720e2b38 206 Gene3D G3DSA:3.40.50.2300 3 128 2.7E-28 T 11-11-2016 AUP74_RS03110 e97c5d7a6e12658283337dc4720e2b38 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 188 4.3E-11 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS03110 e97c5d7a6e12658283337dc4720e2b38 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 146 160 4.3E-11 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS03110 e97c5d7a6e12658283337dc4720e2b38 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 176 4.3E-11 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS05885 aa125eda69081ff0d29d2e543ac37b96 142 Pfam PF09335 SNARE associated Golgi protein 31 136 1.8E-15 T 11-11-2016 IPR032816 SNARE associated Golgi protein AUP74_RS05885 aa125eda69081ff0d29d2e543ac37b96 142 ProDom PD085709 MEMBRANE RP436 UNCHARACTERIZED INTEGRAL PREDICTED TRANSMEMBRANE 31 122 7.0E-5 T 11-11-2016 IPR020143 Uncharacterised protein family, RP436 AUP74_RS02455 0c732a16db678b4f092f23a0f5398b86 67 TIGRFAM TIGR02449 TIGR02449: TIGR02449 family protein 4 66 2.5E-23 T 11-11-2016 IPR012662 Conserved hypothetical protein CHP02449 AUP74_RS14510 24800541be933a76ff8b92e2b208a63a 404 SUPERFAMILY SSF51905 5 179 4.54E-59 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS14510 24800541be933a76ff8b92e2b208a63a 404 SUPERFAMILY SSF51905 271 381 4.54E-59 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS14510 24800541be933a76ff8b92e2b208a63a 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 9.4E-30 T 11-11-2016 AUP74_RS14510 24800541be933a76ff8b92e2b208a63a 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 284 299 9.4E-30 T 11-11-2016 AUP74_RS14510 24800541be933a76ff8b92e2b208a63a 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 336 352 9.4E-30 T 11-11-2016 AUP74_RS14510 24800541be933a76ff8b92e2b208a63a 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 158 173 9.4E-30 T 11-11-2016 AUP74_RS14510 24800541be933a76ff8b92e2b208a63a 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 299 315 9.4E-30 T 11-11-2016 AUP74_RS14510 24800541be933a76ff8b92e2b208a63a 404 Pfam PF01494 FAD binding domain 5 350 6.6E-56 T 11-11-2016 IPR002938 FAD-binding domain GO:0071949 AUP74_RS14510 24800541be933a76ff8b92e2b208a63a 404 Gene3D G3DSA:3.30.9.10 171 277 3.1E-7 T 11-11-2016 AUP74_RS14510 24800541be933a76ff8b92e2b208a63a 404 Gene3D G3DSA:3.30.9.10 333 351 3.1E-7 T 11-11-2016 AUP74_RS14510 24800541be933a76ff8b92e2b208a63a 404 Gene3D G3DSA:3.50.50.60 3 170 4.1E-44 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS14510 24800541be933a76ff8b92e2b208a63a 404 Gene3D G3DSA:3.50.50.60 282 322 4.1E-44 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS00320 87b3a3cbb336b5255561f39bf49f1c5e 423 SUPERFAMILY SSF53383 63 409 2.71E-37 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase AUP74_RS00320 87b3a3cbb336b5255561f39bf49f1c5e 423 Pfam PF12897 Alanine-glyoxylate amino-transferase 7 421 4.7E-149 T 11-11-2016 IPR024551 Aminotransferase, putative AUP74_RS00320 87b3a3cbb336b5255561f39bf49f1c5e 423 Gene3D G3DSA:3.90.1150.10 6 164 4.6E-34 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS00320 87b3a3cbb336b5255561f39bf49f1c5e 423 Gene3D G3DSA:3.90.1150.10 250 417 2.7E-51 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS02345 48e0f024fd429e4a5b46bd47e6cd5651 277 Hamap MF_00008 Thymidylate synthase [thyA]. 1 277 40.536 T 11-11-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 AUP74_RS02345 48e0f024fd429e4a5b46bd47e6cd5651 277 Pfam PF00303 Thymidylate synthase 2 277 8.8E-119 T 11-11-2016 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 AUP74_RS02345 48e0f024fd429e4a5b46bd47e6cd5651 277 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 85 277 1.0E-90 T 11-11-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 AUP74_RS02345 48e0f024fd429e4a5b46bd47e6cd5651 277 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 2 86 5.8E-42 T 11-11-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 AUP74_RS02345 48e0f024fd429e4a5b46bd47e6cd5651 277 Gene3D G3DSA:3.30.572.10 1 277 2.3E-128 T 11-11-2016 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 AUP74_RS02345 48e0f024fd429e4a5b46bd47e6cd5651 277 PRINTS PR00108 Thymidylate synthase family signature 42 63 1.2E-40 T 11-11-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 AUP74_RS02345 48e0f024fd429e4a5b46bd47e6cd5651 277 PRINTS PR00108 Thymidylate synthase family signature 210 227 1.2E-40 T 11-11-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 AUP74_RS02345 48e0f024fd429e4a5b46bd47e6cd5651 277 PRINTS PR00108 Thymidylate synthase family signature 172 198 1.2E-40 T 11-11-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 AUP74_RS02345 48e0f024fd429e4a5b46bd47e6cd5651 277 PRINTS PR00108 Thymidylate synthase family signature 115 134 1.2E-40 T 11-11-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 AUP74_RS02345 48e0f024fd429e4a5b46bd47e6cd5651 277 SUPERFAMILY SSF55831 1 277 2.62E-125 T 11-11-2016 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 AUP74_RS07445 f73f4f1eb4266784dc9dc384afaae5a6 130 Gene3D G3DSA:3.10.180.10 2 121 7.3E-26 T 11-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AUP74_RS07445 f73f4f1eb4266784dc9dc384afaae5a6 130 SUPERFAMILY SSF54593 2 121 3.36E-26 T 11-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AUP74_RS07445 f73f4f1eb4266784dc9dc384afaae5a6 130 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 117 2.3E-8 T 11-11-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AUP74_RS09835 2db9d69135f8cfef417e247e234aef3e 451 Pfam PF10996 Beta-Casp domain 247 364 1.6E-22 T 11-11-2016 IPR022712 Beta-Casp domain AUP74_RS09835 2db9d69135f8cfef417e247e234aef3e 451 SUPERFAMILY SSF56281 2 447 1.49E-117 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS09835 2db9d69135f8cfef417e247e234aef3e 451 SMART SM01027 246 365 6.9E-49 T 11-11-2016 IPR022712 Beta-Casp domain AUP74_RS09835 2db9d69135f8cfef417e247e234aef3e 451 Pfam PF12706 Beta-lactamase superfamily domain 24 212 4.5E-12 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS09835 2db9d69135f8cfef417e247e234aef3e 451 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 378 433 1.5E-9 T 11-11-2016 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain AUP74_RS09835 2db9d69135f8cfef417e247e234aef3e 451 Gene3D G3DSA:3.60.15.10 2 100 3.0E-44 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS09835 2db9d69135f8cfef417e247e234aef3e 451 Gene3D G3DSA:3.60.15.10 135 252 3.0E-44 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS09835 2db9d69135f8cfef417e247e234aef3e 451 SMART SM00849 13 222 6.8E-11 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS08615 53313d6073af486e26ea2455bd39af88 138 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 21 37 - T 11-11-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 AUP74_RS08615 53313d6073af486e26ea2455bd39af88 138 Pfam PF00472 RF-1 domain 6 132 3.7E-27 T 11-11-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 AUP74_RS08615 53313d6073af486e26ea2455bd39af88 138 SUPERFAMILY SSF75620 7 113 5.1E-12 T 11-11-2016 AUP74_RS08615 53313d6073af486e26ea2455bd39af88 138 Gene3D G3DSA:3.30.160.200 3 105 3.0E-33 T 11-11-2016 AUP74_RS15935 90e6a9f455f3ff178a04ea6fb9a99010 355 SUPERFAMILY SSF53756 2 297 8.85E-15 T 11-11-2016 AUP74_RS15935 90e6a9f455f3ff178a04ea6fb9a99010 355 Pfam PF13528 Glycosyl transferase family 1 2 301 1.8E-46 T 11-11-2016 AUP74_RS15935 90e6a9f455f3ff178a04ea6fb9a99010 355 Gene3D G3DSA:3.40.50.2000 224 297 3.0E-9 T 11-11-2016 AUP74_RS15935 90e6a9f455f3ff178a04ea6fb9a99010 355 Gene3D G3DSA:3.40.50.2000 9 118 9.2E-4 T 11-11-2016 AUP74_RS15935 90e6a9f455f3ff178a04ea6fb9a99010 355 TIGRFAM TIGR00661 MJ1255: conserved hypothetical protein 2 301 6.1E-63 T 11-11-2016 IPR005262 Conserved hypothetical protein CHP00661 AUP74_RS06810 f7151014b1b4facf2ff8ef88ff86424e 397 Gene3D G3DSA:3.40.50.300 4 214 1.4E-67 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS06810 f7151014b1b4facf2ff8ef88ff86424e 397 SUPERFAMILY SSF50447 208 304 1.81E-29 T 11-11-2016 IPR009000 Translation protein, beta-barrel domain AUP74_RS06810 f7151014b1b4facf2ff8ef88ff86424e 397 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 397 59.628 T 11-11-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AUP74_RS06810 f7151014b1b4facf2ff8ef88ff86424e 397 PRINTS PR00315 GTP-binding elongation factor signature 94 105 2.1E-24 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AUP74_RS06810 f7151014b1b4facf2ff8ef88ff86424e 397 PRINTS PR00315 GTP-binding elongation factor signature 131 140 2.1E-24 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AUP74_RS06810 f7151014b1b4facf2ff8ef88ff86424e 397 PRINTS PR00315 GTP-binding elongation factor signature 78 88 2.1E-24 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AUP74_RS06810 f7151014b1b4facf2ff8ef88ff86424e 397 PRINTS PR00315 GTP-binding elongation factor signature 58 66 2.1E-24 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AUP74_RS06810 f7151014b1b4facf2ff8ef88ff86424e 397 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.1E-24 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AUP74_RS06810 f7151014b1b4facf2ff8ef88ff86424e 397 SUPERFAMILY SSF52540 6 222 3.8E-61 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS06810 f7151014b1b4facf2ff8ef88ff86424e 397 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 11-11-2016 IPR031157 Tr-type G domain, conserved site AUP74_RS06810 f7151014b1b4facf2ff8ef88ff86424e 397 Gene3D G3DSA:2.40.30.10 303 396 5.5E-48 T 11-11-2016 AUP74_RS06810 f7151014b1b4facf2ff8ef88ff86424e 397 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 397 4.5E-226 T 11-11-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AUP74_RS06810 f7151014b1b4facf2ff8ef88ff86424e 397 Gene3D G3DSA:2.40.30.10 215 301 1.8E-35 T 11-11-2016 AUP74_RS06810 f7151014b1b4facf2ff8ef88ff86424e 397 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 148 9.6E-15 T 11-11-2016 IPR005225 Small GTP-binding protein domain GO:0005525 AUP74_RS06810 f7151014b1b4facf2ff8ef88ff86424e 397 Pfam PF03144 Elongation factor Tu domain 2 228 296 6.3E-17 T 11-11-2016 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AUP74_RS06810 f7151014b1b4facf2ff8ef88ff86424e 397 SUPERFAMILY SSF50465 305 397 5.47E-36 T 11-11-2016 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal AUP74_RS06810 f7151014b1b4facf2ff8ef88ff86424e 397 Pfam PF03143 Elongation factor Tu C-terminal domain 301 395 7.5E-34 T 11-11-2016 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal AUP74_RS06810 f7151014b1b4facf2ff8ef88ff86424e 397 Pfam PF00009 Elongation factor Tu GTP binding domain 10 204 2.1E-58 T 11-11-2016 AUP74_RS05175 841cdbefd1204a7a711bbbf3cf1ec3d1 398 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 35 387 4.3E-100 T 11-11-2016 AUP74_RS05175 841cdbefd1204a7a711bbbf3cf1ec3d1 398 SUPERFAMILY SSF48208 6 396 1.29E-124 T 11-11-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 AUP74_RS05175 841cdbefd1204a7a711bbbf3cf1ec3d1 398 Gene3D G3DSA:1.50.10.10 5 397 3.1E-121 T 11-11-2016 IPR012341 Six-hairpin glycosidase GO:0003824 AUP74_RS04120 171a6600c926d41d3c3904ffdfbfd9be 694 SUPERFAMILY SSF52540 216 456 5.29E-58 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04120 171a6600c926d41d3c3904ffdfbfd9be 694 Pfam PF17191 RecG wedge domain 9 169 1.5E-17 T 11-11-2016 IPR033454 RecG, wedge domain AUP74_RS04120 171a6600c926d41d3c3904ffdfbfd9be 694 SMART SM00487 264 462 4.5E-31 T 11-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain AUP74_RS04120 171a6600c926d41d3c3904ffdfbfd9be 694 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 27 666 1.4E-224 T 11-11-2016 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 AUP74_RS04120 171a6600c926d41d3c3904ffdfbfd9be 694 SMART SM00490 507 591 3.7E-23 T 11-11-2016 IPR001650 Helicase, C-terminal AUP74_RS04120 171a6600c926d41d3c3904ffdfbfd9be 694 Gene3D G3DSA:3.40.50.300 253 456 3.9E-57 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04120 171a6600c926d41d3c3904ffdfbfd9be 694 Pfam PF00271 Helicase conserved C-terminal domain 476 590 6.5E-20 T 11-11-2016 IPR001650 Helicase, C-terminal AUP74_RS04120 171a6600c926d41d3c3904ffdfbfd9be 694 Gene3D G3DSA:2.40.50.140 45 138 2.2E-21 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS04120 171a6600c926d41d3c3904ffdfbfd9be 694 SUPERFAMILY SSF52540 387 601 2.72E-41 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04120 171a6600c926d41d3c3904ffdfbfd9be 694 Gene3D G3DSA:1.10.150.20 4 34 8.7E-4 T 11-11-2016 AUP74_RS04120 171a6600c926d41d3c3904ffdfbfd9be 694 SUPERFAMILY SSF50249 6 171 4.8E-38 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS04120 171a6600c926d41d3c3904ffdfbfd9be 694 Pfam PF00270 DEAD/DEAH box helicase 290 434 1.3E-16 T 11-11-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AUP74_RS04120 171a6600c926d41d3c3904ffdfbfd9be 694 Gene3D G3DSA:3.40.50.300 457 640 6.3E-45 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS16225 324a6479e7c56c5f809b50f9e41e9631 969 Pfam PF03477 ATP cone domain 26 123 3.4E-19 T 11-11-2016 IPR005144 ATP-cone domain Reactome: R-HSA-499943 AUP74_RS16225 324a6479e7c56c5f809b50f9e41e9631 969 Pfam PF03477 ATP cone domain 147 231 1.2E-7 T 11-11-2016 IPR005144 ATP-cone domain Reactome: R-HSA-499943 AUP74_RS16225 324a6479e7c56c5f809b50f9e41e9631 969 SUPERFAMILY SSF51998 841 908 1.13E-177 T 11-11-2016 AUP74_RS16225 324a6479e7c56c5f809b50f9e41e9631 969 SUPERFAMILY SSF51998 368 810 1.13E-177 T 11-11-2016 AUP74_RS16225 324a6479e7c56c5f809b50f9e41e9631 969 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 295 908 1.9E-216 T 11-11-2016 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AUP74_RS16225 324a6479e7c56c5f809b50f9e41e9631 969 PRINTS PR01183 Ribonucleotide reductase large chain signature 761 788 1.0E-45 T 11-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AUP74_RS16225 324a6479e7c56c5f809b50f9e41e9631 969 PRINTS PR01183 Ribonucleotide reductase large chain signature 444 463 1.0E-45 T 11-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AUP74_RS16225 324a6479e7c56c5f809b50f9e41e9631 969 PRINTS PR01183 Ribonucleotide reductase large chain signature 684 707 1.0E-45 T 11-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AUP74_RS16225 324a6479e7c56c5f809b50f9e41e9631 969 PRINTS PR01183 Ribonucleotide reductase large chain signature 618 641 1.0E-45 T 11-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AUP74_RS16225 324a6479e7c56c5f809b50f9e41e9631 969 PRINTS PR01183 Ribonucleotide reductase large chain signature 579 590 1.0E-45 T 11-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AUP74_RS16225 324a6479e7c56c5f809b50f9e41e9631 969 PRINTS PR01183 Ribonucleotide reductase large chain signature 656 678 1.0E-45 T 11-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AUP74_RS16225 324a6479e7c56c5f809b50f9e41e9631 969 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 750 772 - T 11-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AUP74_RS16225 324a6479e7c56c5f809b50f9e41e9631 969 Pfam PF02867 Ribonucleotide reductase, barrel domain 369 906 1.2E-183 T 11-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AUP74_RS16225 324a6479e7c56c5f809b50f9e41e9631 969 Gene3D G3DSA:3.20.70.20 283 490 2.0E-80 T 11-11-2016 AUP74_RS16225 324a6479e7c56c5f809b50f9e41e9631 969 Gene3D G3DSA:3.20.70.20 545 704 2.0E-80 T 11-11-2016 AUP74_RS16225 324a6479e7c56c5f809b50f9e41e9631 969 Gene3D G3DSA:3.20.70.20 761 806 2.0E-80 T 11-11-2016 AUP74_RS16225 324a6479e7c56c5f809b50f9e41e9631 969 Gene3D G3DSA:3.20.70.20 867 907 2.0E-80 T 11-11-2016 AUP74_RS16225 324a6479e7c56c5f809b50f9e41e9631 969 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 292 363 1.7E-21 T 11-11-2016 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AUP74_RS16225 324a6479e7c56c5f809b50f9e41e9631 969 SUPERFAMILY SSF48168 151 367 3.4E-61 T 11-11-2016 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AUP74_RS03735 0c6e0f6f4c7595e0fa6f295dd3ba76bb 116 SUPERFAMILY SSF101386 3 97 7.66E-22 T 11-11-2016 AUP74_RS03735 0c6e0f6f4c7595e0fa6f295dd3ba76bb 116 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 2 93 20.55 T 11-11-2016 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 AUP74_RS03735 0c6e0f6f4c7595e0fa6f295dd3ba76bb 116 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 6 94 1.3E-11 T 11-11-2016 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 AUP74_RS03735 0c6e0f6f4c7595e0fa6f295dd3ba76bb 116 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 5 93 3.0E-27 T 11-11-2016 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 AUP74_RS12550 abef22566ab82ef3842ba8294b95a1b3 337 SMART SM00829 10 335 1.4E-23 T 11-11-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AUP74_RS12550 abef22566ab82ef3842ba8294b95a1b3 337 SUPERFAMILY SSF50129 1 166 2.28E-30 T 11-11-2016 IPR011032 GroES-like AUP74_RS12550 abef22566ab82ef3842ba8294b95a1b3 337 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 87 1.0E-6 T 11-11-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AUP74_RS12550 abef22566ab82ef3842ba8294b95a1b3 337 Gene3D G3DSA:3.90.180.10 1 168 3.4E-35 T 11-11-2016 IPR011032 GroES-like AUP74_RS12550 abef22566ab82ef3842ba8294b95a1b3 337 SUPERFAMILY SSF51735 138 312 8.64E-48 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS12550 abef22566ab82ef3842ba8294b95a1b3 337 Gene3D G3DSA:3.40.50.720 169 283 3.3E-37 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS12550 abef22566ab82ef3842ba8294b95a1b3 337 Pfam PF00107 Zinc-binding dehydrogenase 172 296 3.9E-34 T 11-11-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AUP74_RS13145 20b43159ec090ccc77cab6f9de4a2105 426 Gene3D G3DSA:3.40.50.2000 170 356 3.1E-32 T 11-11-2016 AUP74_RS13145 20b43159ec090ccc77cab6f9de4a2105 426 Pfam PF00534 Glycosyl transferases group 1 190 354 3.3E-29 T 11-11-2016 IPR001296 Glycosyl transferase, family 1 AUP74_RS13145 20b43159ec090ccc77cab6f9de4a2105 426 SUPERFAMILY SSF53756 3 380 3.18E-82 T 11-11-2016 AUP74_RS13145 20b43159ec090ccc77cab6f9de4a2105 426 Pfam PF13439 Glycosyltransferase Family 4 14 180 7.7E-31 T 11-11-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AUP74_RS12985 3a8a1b6d894a1c24e5a31658f7171f11 552 Pfam PF01235 Sodium:alanine symporter family 59 548 3.3E-142 T 11-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AUP74_RS12985 3a8a1b6d894a1c24e5a31658f7171f11 552 TIGRFAM TIGR00835 agcS: amino acid carrier protein 23 545 3.0E-173 T 11-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AUP74_RS12985 3a8a1b6d894a1c24e5a31658f7171f11 552 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 93 108 - T 11-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AUP74_RS12985 3a8a1b6d894a1c24e5a31658f7171f11 552 PRINTS PR00175 Sodium/alanine symporter signature 93 115 2.2E-52 T 11-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AUP74_RS12985 3a8a1b6d894a1c24e5a31658f7171f11 552 PRINTS PR00175 Sodium/alanine symporter signature 455 477 2.2E-52 T 11-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AUP74_RS12985 3a8a1b6d894a1c24e5a31658f7171f11 552 PRINTS PR00175 Sodium/alanine symporter signature 514 534 2.2E-52 T 11-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AUP74_RS12985 3a8a1b6d894a1c24e5a31658f7171f11 552 PRINTS PR00175 Sodium/alanine symporter signature 212 231 2.2E-52 T 11-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AUP74_RS12985 3a8a1b6d894a1c24e5a31658f7171f11 552 PRINTS PR00175 Sodium/alanine symporter signature 184 202 2.2E-52 T 11-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AUP74_RS12985 3a8a1b6d894a1c24e5a31658f7171f11 552 PRINTS PR00175 Sodium/alanine symporter signature 307 325 2.2E-52 T 11-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AUP74_RS02110 9ac57f5fec09ae93f70cd32d1e5d3cb0 432 SUPERFAMILY SSF53187 28 234 1.89E-87 T 11-11-2016 AUP74_RS02110 9ac57f5fec09ae93f70cd32d1e5d3cb0 432 SUPERFAMILY SSF53187 336 430 1.89E-87 T 11-11-2016 AUP74_RS02110 9ac57f5fec09ae93f70cd32d1e5d3cb0 432 Gene3D G3DSA:3.30.70.360 218 335 6.5E-36 T 11-11-2016 IPR011650 Peptidase M20, dimerisation domain AUP74_RS02110 9ac57f5fec09ae93f70cd32d1e5d3cb0 432 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 38 415 4.1E-106 T 11-11-2016 IPR017439 Amidohydrolase GO:0016787 AUP74_RS02110 9ac57f5fec09ae93f70cd32d1e5d3cb0 432 Pfam PF01546 Peptidase family M20/M25/M40 95 423 1.4E-36 T 11-11-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 AUP74_RS02110 9ac57f5fec09ae93f70cd32d1e5d3cb0 432 Pfam PF07687 Peptidase dimerisation domain 222 318 1.4E-8 T 11-11-2016 IPR011650 Peptidase M20, dimerisation domain AUP74_RS02110 9ac57f5fec09ae93f70cd32d1e5d3cb0 432 Gene3D G3DSA:3.40.630.10 336 430 3.3E-106 T 11-11-2016 AUP74_RS02110 9ac57f5fec09ae93f70cd32d1e5d3cb0 432 Gene3D G3DSA:3.40.630.10 21 215 3.3E-106 T 11-11-2016 AUP74_RS02110 9ac57f5fec09ae93f70cd32d1e5d3cb0 432 PIRSF PIRSF005962 21 431 1.1E-125 T 11-11-2016 IPR017439 Amidohydrolase GO:0016787 AUP74_RS02110 9ac57f5fec09ae93f70cd32d1e5d3cb0 432 SUPERFAMILY SSF55031 220 328 8.11E-28 T 11-11-2016 IPR011650 Peptidase M20, dimerisation domain AUP74_RS00950 bb0ce3d1c5c7c562e4cc83aabcd08a2e 136 Gene3D G3DSA:1.10.10.10 5 82 1.4E-30 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS00950 bb0ce3d1c5c7c562e4cc83aabcd08a2e 136 SUPERFAMILY SSF46785 6 133 1.4E-41 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS00950 bb0ce3d1c5c7c562e4cc83aabcd08a2e 136 Pfam PF01475 Ferric uptake regulator family 10 130 1.3E-44 T 11-11-2016 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 AUP74_RS03650 8e585a3da586ba69dd113ae92351bd24 195 Pfam PF06736 Protein of unknown function (DUF1211) 5 89 7.9E-27 T 11-11-2016 IPR010617 Endosomal/lysomomal potassium channel TMEM175 GO:0005267 AUP74_RS04535 6ef6ab41c84d6450a68ca5303efd546b 295 PIRSF PIRSF026649 2 292 1.7E-80 T 11-11-2016 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 AUP74_RS04535 6ef6ab41c84d6450a68ca5303efd546b 295 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 7 283 1.6E-48 T 11-11-2016 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 AUP74_RS11715 9195e3241003c35726ee5d11dc8fd810 428 SUPERFAMILY SSF53756 74 422 1.88E-53 T 11-11-2016 AUP74_RS11715 9195e3241003c35726ee5d11dc8fd810 428 Gene3D G3DSA:3.40.50.2000 240 401 1.1E-28 T 11-11-2016 AUP74_RS11715 9195e3241003c35726ee5d11dc8fd810 428 Pfam PF00534 Glycosyl transferases group 1 247 402 3.5E-32 T 11-11-2016 IPR001296 Glycosyl transferase, family 1 AUP74_RS01610 e4c9b2840add109595f108ef002606cc 244 SUPERFAMILY SSF46785 155 234 5.19E-18 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS01610 e4c9b2840add109595f108ef002606cc 244 SMART SM00100 20 141 1.2E-13 T 11-11-2016 IPR000595 Cyclic nucleotide-binding domain AUP74_RS01610 e4c9b2840add109595f108ef002606cc 244 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 183 199 3.0E-10 T 11-11-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AUP74_RS01610 e4c9b2840add109595f108ef002606cc 244 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 199 214 3.0E-10 T 11-11-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AUP74_RS01610 e4c9b2840add109595f108ef002606cc 244 Pfam PF00027 Cyclic nucleotide-binding domain 39 124 1.5E-13 T 11-11-2016 IPR000595 Cyclic nucleotide-binding domain AUP74_RS01610 e4c9b2840add109595f108ef002606cc 244 Gene3D G3DSA:1.10.10.10 160 234 2.8E-25 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS01610 e4c9b2840add109595f108ef002606cc 244 SMART SM00419 177 225 9.1E-16 T 11-11-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AUP74_RS01610 e4c9b2840add109595f108ef002606cc 244 Pfam PF13545 Crp-like helix-turn-helix domain 159 231 9.3E-17 T 11-11-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AUP74_RS01610 e4c9b2840add109595f108ef002606cc 244 Gene3D G3DSA:2.60.120.10 9 159 3.8E-27 T 11-11-2016 IPR014710 RmlC-like jelly roll fold AUP74_RS01610 e4c9b2840add109595f108ef002606cc 244 SUPERFAMILY SSF51206 13 152 8.51E-29 T 11-11-2016 IPR018490 Cyclic nucleotide-binding-like AUP74_RS02270 eae62d0f061c22f69743a6eac00c3323 265 SUPERFAMILY SSF54506 1 263 3.73E-79 T 11-11-2016 AUP74_RS02270 eae62d0f061c22f69743a6eac00c3323 265 PIRSF PIRSF016184 1 263 3.0E-50 T 11-11-2016 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 AUP74_RS02270 eae62d0f061c22f69743a6eac00c3323 265 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 1 238 2.5E-33 T 11-11-2016 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 AUP74_RS02270 eae62d0f061c22f69743a6eac00c3323 265 Pfam PF02567 Phenazine biosynthesis-like protein 9 258 1.6E-57 T 11-11-2016 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 AUP74_RS02270 eae62d0f061c22f69743a6eac00c3323 265 Gene3D G3DSA:3.10.310.10 142 251 3.3E-40 T 11-11-2016 AUP74_RS02270 eae62d0f061c22f69743a6eac00c3323 265 Gene3D G3DSA:3.10.310.10 1 125 5.6E-45 T 11-11-2016 AUP74_RS01965 1ad0f15050974c4735909cd811f37e09 217 Pfam PF03734 L,D-transpeptidase catalytic domain 81 215 1.9E-20 T 11-11-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 AUP74_RS01965 1ad0f15050974c4735909cd811f37e09 217 SUPERFAMILY SSF141523 78 215 1.7E-27 T 11-11-2016 AUP74_RS01965 1ad0f15050974c4735909cd811f37e09 217 Gene3D G3DSA:2.40.440.10 158 216 3.6E-18 T 11-11-2016 AUP74_RS01965 1ad0f15050974c4735909cd811f37e09 217 Gene3D G3DSA:2.40.440.10 79 124 3.6E-18 T 11-11-2016 AUP74_RS07845 3cfe0bf37880975fc09371d5dc68e42f 725 SUPERFAMILY SSF103515 439 725 2.35E-19 T 11-11-2016 IPR005546 Autotransporter beta-domain AUP74_RS07845 3cfe0bf37880975fc09371d5dc68e42f 725 SUPERFAMILY SSF52266 376 404 1.5E-7 T 11-11-2016 IPR013830 SGNH hydrolase-type esterase domain AUP74_RS07845 3cfe0bf37880975fc09371d5dc68e42f 725 SUPERFAMILY SSF52266 232 334 1.5E-7 T 11-11-2016 IPR013830 SGNH hydrolase-type esterase domain AUP74_RS07845 3cfe0bf37880975fc09371d5dc68e42f 725 Gene3D G3DSA:3.40.50.1110 25 129 7.7E-6 T 11-11-2016 IPR013830 SGNH hydrolase-type esterase domain AUP74_RS07845 3cfe0bf37880975fc09371d5dc68e42f 725 Gene3D G3DSA:3.40.50.1110 222 407 2.1E-28 T 11-11-2016 IPR013830 SGNH hydrolase-type esterase domain AUP74_RS07845 3cfe0bf37880975fc09371d5dc68e42f 725 Pfam PF03797 Autotransporter beta-domain 466 699 3.3E-14 T 11-11-2016 IPR005546 Autotransporter beta-domain AUP74_RS07845 3cfe0bf37880975fc09371d5dc68e42f 725 Gene3D G3DSA:2.40.128.130 419 725 1.8E-19 T 11-11-2016 IPR005546 Autotransporter beta-domain AUP74_RS07845 3cfe0bf37880975fc09371d5dc68e42f 725 SMART SM00869 441 690 9.9E-6 T 11-11-2016 IPR005546 Autotransporter beta-domain AUP74_RS10470 bae873c88420b97c8244284a85f3cfae 273 SUPERFAMILY SSF50969 79 256 7.14E-13 T 11-11-2016 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like AUP74_RS10470 bae873c88420b97c8244284a85f3cfae 273 Gene3D G3DSA:2.130.10.10 92 256 4.9E-6 T 11-11-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 AUP74_RS10470 bae873c88420b97c8244284a85f3cfae 273 Pfam PF05096 Glutamine cyclotransferase 26 254 1.3E-72 T 11-11-2016 IPR007788 Glutamine cyclotransferase AUP74_RS00360 2e25448b65522944420d6873cec572b1 465 SMART SM00729 162 382 2.2E-60 T 11-11-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 AUP74_RS00360 2e25448b65522944420d6873cec572b1 465 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 18 456 2.0E-184 T 11-11-2016 AUP74_RS00360 2e25448b65522944420d6873cec572b1 465 Pfam PF01938 TRAM domain 393 456 2.0E-17 T 11-11-2016 IPR002792 TRAM domain AUP74_RS00360 2e25448b65522944420d6873cec572b1 465 Pfam PF04055 Radical SAM superfamily 166 340 1.3E-29 T 11-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 AUP74_RS00360 2e25448b65522944420d6873cec572b1 465 Gene3D G3DSA:3.80.30.20 162 395 1.7E-79 T 11-11-2016 IPR023404 Radical SAM, alpha/beta horseshoe AUP74_RS00360 2e25448b65522944420d6873cec572b1 465 SUPERFAMILY SSF102114 140 386 4.58E-62 T 11-11-2016 AUP74_RS00360 2e25448b65522944420d6873cec572b1 465 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 17 456 73.245 T 11-11-2016 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 AUP74_RS00360 2e25448b65522944420d6873cec572b1 465 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 18 453 1.4E-148 T 11-11-2016 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 AUP74_RS00360 2e25448b65522944420d6873cec572b1 465 Pfam PF00919 Uncharacterized protein family UPF0004 18 118 3.6E-28 T 11-11-2016 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 AUP74_RS00360 2e25448b65522944420d6873cec572b1 465 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 166 186 - T 11-11-2016 IPR020612 Methylthiotransferase, conserved site GO:0051539 AUP74_RS04920 6524fc87231102103194f9d864fc8f1f 235 Pfam PF13709 Domain of unknown function (DUF4159) 37 233 2.2E-47 T 11-11-2016 IPR025297 Domain of unknown function DUF4159 AUP74_RS11255 a5d062e01954d23236d4e55f332226b6 511 Hamap MF_01599 Na(+)/H(+) antiporter NhaB [nhaB]. 9 511 309.541 T 11-11-2016 IPR004671 Na+/H+ antiporter NhaB GO:0006814|GO:0015385|GO:0016021 AUP74_RS11255 a5d062e01954d23236d4e55f332226b6 511 Pfam PF06450 Bacterial Na+/H+ antiporter B (NhaB) 15 509 6.8E-231 T 11-11-2016 IPR004671 Na+/H+ antiporter NhaB GO:0006814|GO:0015385|GO:0016021 AUP74_RS03535 1a4cab2ffeaf709e732ce2479797f684 242 Gene3D G3DSA:3.30.1380.10 136 242 7.3E-15 T 11-11-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 AUP74_RS03535 1a4cab2ffeaf709e732ce2479797f684 242 SUPERFAMILY SSF55166 125 242 2.98E-11 T 11-11-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 AUP74_RS03535 1a4cab2ffeaf709e732ce2479797f684 242 Pfam PF08291 Peptidase M15 156 211 2.2E-6 T 11-11-2016 IPR013230 Peptidase M15A, C-terminal MetaCyc: PWY-6470 AUP74_RS04990 acd50a1a44a521d641a2fa4bd3552380 269 SUPERFAMILY SSF53335 31 205 5.3E-30 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS04990 acd50a1a44a521d641a2fa4bd3552380 269 SMART SM00138 1 213 1.1E-6 T 11-11-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AUP74_RS04990 acd50a1a44a521d641a2fa4bd3552380 269 PRINTS PR00996 Glutamate methyltransferase family signature 92 108 2.8E-7 T 11-11-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AUP74_RS04990 acd50a1a44a521d641a2fa4bd3552380 269 PRINTS PR00996 Glutamate methyltransferase family signature 183 206 2.8E-7 T 11-11-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AUP74_RS04990 acd50a1a44a521d641a2fa4bd3552380 269 PRINTS PR00996 Glutamate methyltransferase family signature 164 178 2.8E-7 T 11-11-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AUP74_RS04990 acd50a1a44a521d641a2fa4bd3552380 269 PRINTS PR00996 Glutamate methyltransferase family signature 60 80 2.8E-7 T 11-11-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AUP74_RS04990 acd50a1a44a521d641a2fa4bd3552380 269 Pfam PF01739 CheR methyltransferase, SAM binding domain 31 200 1.2E-25 T 11-11-2016 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal AUP74_RS04990 acd50a1a44a521d641a2fa4bd3552380 269 Gene3D G3DSA:3.40.50.150 31 201 3.5E-33 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS11620 ae50f8ec6e3cec209999805932dde8a1 156 Pfam PF13185 GAF domain 39 146 6.0E-11 T 11-11-2016 IPR003018 GAF domain GO:0005515 AUP74_RS11620 ae50f8ec6e3cec209999805932dde8a1 156 Gene3D G3DSA:3.30.450.40 4 152 1.5E-49 T 11-11-2016 IPR029016 GAF domain-like AUP74_RS11620 ae50f8ec6e3cec209999805932dde8a1 156 ProSitePatterns PS01320 Uncharacterized protein family UPF0067 signature. 90 107 - T 11-11-2016 IPR000614 Free Met sulfoxide reductase conserved site AUP74_RS11620 ae50f8ec6e3cec209999805932dde8a1 156 SUPERFAMILY SSF55781 5 147 2.45E-39 T 11-11-2016 IPR029016 GAF domain-like AUP74_RS15630 b65d6d16ba72302097f02580bd941e5e 281 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 233 259 - T 11-11-2016 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981 AUP74_RS15630 b65d6d16ba72302097f02580bd941e5e 281 Pfam PF01148 Cytidylyltransferase family 3 270 1.0E-61 T 11-11-2016 AUP74_RS12500 799c1759ab3903fb944f88c109f0f50c 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.2E-26 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS12500 799c1759ab3903fb944f88c109f0f50c 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.2E-26 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS12500 799c1759ab3903fb944f88c109f0f50c 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.2E-26 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS12500 799c1759ab3903fb944f88c109f0f50c 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.2E-26 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS12500 799c1759ab3903fb944f88c109f0f50c 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.2E-26 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS12500 799c1759ab3903fb944f88c109f0f50c 248 Pfam PF00106 short chain dehydrogenase 8 200 2.0E-60 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS12500 799c1759ab3903fb944f88c109f0f50c 248 Gene3D G3DSA:3.40.50.720 1 231 3.0E-75 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS12500 799c1759ab3903fb944f88c109f0f50c 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 192 1.3E-4 T 11-11-2016 AUP74_RS12500 799c1759ab3903fb944f88c109f0f50c 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 2.3E-11 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS12500 799c1759ab3903fb944f88c109f0f50c 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 2.3E-11 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS12500 799c1759ab3903fb944f88c109f0f50c 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 2.3E-11 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS12500 799c1759ab3903fb944f88c109f0f50c 248 SUPERFAMILY SSF51735 1 232 5.79E-72 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS12500 799c1759ab3903fb944f88c109f0f50c 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 11-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AUP74_RS10770 fcb13014e5fe9b9f8626c10df8922394 735 Pfam PF04632 Fusaric acid resistance protein family 13 565 3.9E-55 T 11-11-2016 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0006810 AUP74_RS08285 ff1a84a4a0f3af3e6e95702de7de037a 145 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 22 144 30.435 T 11-11-2016 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 AUP74_RS08285 ff1a84a4a0f3af3e6e95702de7de037a 145 SUPERFAMILY SSF109635 8 104 1.16E-36 T 11-11-2016 AUP74_RS08285 ff1a84a4a0f3af3e6e95702de7de037a 145 PRINTS PR00618 DksA/TraR zinc finger signature 120 132 3.7E-5 T 11-11-2016 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria AUP74_RS08285 ff1a84a4a0f3af3e6e95702de7de037a 145 PRINTS PR00618 DksA/TraR zinc finger signature 108 119 3.7E-5 T 11-11-2016 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria AUP74_RS08285 ff1a84a4a0f3af3e6e95702de7de037a 145 SUPERFAMILY SSF57716 105 143 2.14E-10 T 11-11-2016 AUP74_RS08285 ff1a84a4a0f3af3e6e95702de7de037a 145 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 26 134 2.3E-52 T 11-11-2016 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 AUP74_RS08285 ff1a84a4a0f3af3e6e95702de7de037a 145 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 108 132 - T 11-11-2016 IPR020458 Zinc finger, DksA/TraR C4-type conserved site AUP74_RS08285 ff1a84a4a0f3af3e6e95702de7de037a 145 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 104 137 1.4E-11 T 11-11-2016 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 AUP74_RS01680 ab6277176e4699b4ad79cfbf0e3826ce 645 Gene3D G3DSA:2.170.130.10 46 178 5.7E-36 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS01680 ab6277176e4699b4ad79cfbf0e3826ce 645 Pfam PF07715 TonB-dependent Receptor Plug Domain 68 174 1.6E-24 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS01680 ab6277176e4699b4ad79cfbf0e3826ce 645 Gene3D G3DSA:2.40.170.20 179 644 1.1E-61 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS01680 ab6277176e4699b4ad79cfbf0e3826ce 645 SUPERFAMILY SSF56935 59 644 9.58E-98 T 11-11-2016 AUP74_RS01680 ab6277176e4699b4ad79cfbf0e3826ce 645 Pfam PF00593 TonB dependent receptor 407 642 6.2E-23 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS10895 6eead1306a30a81b468b7206a44a77b4 149 Pfam PF03100 CcmE 5 131 2.0E-39 T 11-11-2016 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 AUP74_RS10895 6eead1306a30a81b468b7206a44a77b4 149 Gene3D G3DSA:2.40.50.140 27 125 7.1E-32 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS10895 6eead1306a30a81b468b7206a44a77b4 149 SUPERFAMILY SSF82093 30 136 4.71E-35 T 11-11-2016 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 AUP74_RS10895 6eead1306a30a81b468b7206a44a77b4 149 Hamap MF_01959 Cytochrome c-type biogenesis protein CcmE [ccmE]. 2 141 28.626 T 11-11-2016 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 AUP74_RS10430 d541278b3f033138a08b83d87c1ff8c2 437 PIRSF PIRSF015658 1 433 1.4E-169 T 11-11-2016 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 AUP74_RS10430 d541278b3f033138a08b83d87c1ff8c2 437 TIGRFAM TIGR01109 Na_pump_decarbB: sodium ion-translocating decarboxylase, beta subunit 19 427 7.4E-176 T 11-11-2016 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 AUP74_RS10430 d541278b3f033138a08b83d87c1ff8c2 437 Pfam PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit 20 431 3.4E-155 T 11-11-2016 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 AUP74_RS01895 727fb75d34684fb8d723b75174618c58 139 Gene3D G3DSA:3.10.580.10 5 122 1.6E-21 T 11-11-2016 AUP74_RS01895 727fb75d34684fb8d723b75174618c58 139 SMART SM00116 11 58 0.0013 T 11-11-2016 IPR000644 CBS domain AUP74_RS01895 727fb75d34684fb8d723b75174618c58 139 SMART SM00116 77 124 0.0026 T 11-11-2016 IPR000644 CBS domain AUP74_RS01895 727fb75d34684fb8d723b75174618c58 139 Pfam PF00571 CBS domain 7 53 4.8E-7 T 11-11-2016 IPR000644 CBS domain AUP74_RS01895 727fb75d34684fb8d723b75174618c58 139 Pfam PF00571 CBS domain 70 122 1.4E-8 T 11-11-2016 IPR000644 CBS domain AUP74_RS01895 727fb75d34684fb8d723b75174618c58 139 SUPERFAMILY SSF54631 4 124 3.05E-23 T 11-11-2016 AUP74_RS12410 9f73353164071675a5f50478675def51 237 SMART SM00448 6 117 2.0E-26 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS12410 9f73353164071675a5f50478675def51 237 SUPERFAMILY SSF52172 5 126 2.99E-29 T 11-11-2016 IPR011006 CheY-like superfamily AUP74_RS12410 9f73353164071675a5f50478675def51 237 SUPERFAMILY SSF46894 131 231 4.25E-23 T 11-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AUP74_RS12410 9f73353164071675a5f50478675def51 237 Pfam PF00072 Response regulator receiver domain 8 117 6.6E-19 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS12410 9f73353164071675a5f50478675def51 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 231 8.5E-21 T 11-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AUP74_RS12410 9f73353164071675a5f50478675def51 237 SMART SM00862 155 231 1.2E-18 T 11-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AUP74_RS12410 9f73353164071675a5f50478675def51 237 Gene3D G3DSA:1.10.10.10 131 233 1.5E-25 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS12410 9f73353164071675a5f50478675def51 237 Gene3D G3DSA:3.40.50.2300 6 127 2.0E-27 T 11-11-2016 AUP74_RS14995 97ef774da75a7e530ba3912e5309bf84 368 SUPERFAMILY SSF52151 36 101 8.89E-13 T 11-11-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 AUP74_RS14995 97ef774da75a7e530ba3912e5309bf84 368 SUPERFAMILY SSF52151 157 341 8.89E-13 T 11-11-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 AUP74_RS05120 9ab4fc390502eb11de9f1a6b8df287c8 245 SUPERFAMILY SSF46785 6 71 2.66E-17 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS05120 9ab4fc390502eb11de9f1a6b8df287c8 245 Gene3D G3DSA:1.10.10.10 4 64 1.6E-19 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS05120 9ab4fc390502eb11de9f1a6b8df287c8 245 SMART SM00866 87 227 1.7E-42 T 11-11-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 AUP74_RS05120 9ab4fc390502eb11de9f1a6b8df287c8 245 Gene3D G3DSA:3.40.1410.10 65 234 5.0E-55 T 11-11-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain AUP74_RS05120 9ab4fc390502eb11de9f1a6b8df287c8 245 Pfam PF07702 UTRA domain 88 227 8.1E-44 T 11-11-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 AUP74_RS05120 9ab4fc390502eb11de9f1a6b8df287c8 245 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 67 1.1E-14 T 11-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AUP74_RS05120 9ab4fc390502eb11de9f1a6b8df287c8 245 SUPERFAMILY SSF64288 57 234 8.79E-51 T 11-11-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain AUP74_RS05120 9ab4fc390502eb11de9f1a6b8df287c8 245 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 1.8E-7 T 11-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AUP74_RS05120 9ab4fc390502eb11de9f1a6b8df287c8 245 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 1.8E-7 T 11-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AUP74_RS05120 9ab4fc390502eb11de9f1a6b8df287c8 245 SMART SM00345 10 67 5.2E-15 T 11-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AUP74_RS11525 7046f20bbff3e3cea578faca5c5c94cc 151 Pfam PF06945 Protein of unknown function (DUF1289) 7 50 3.5E-15 T 11-11-2016 IPR010710 Protein of unknown function DUF1289 AUP74_RS04860 970bb21421b2fc97be9b791584c61fcc 543 Gene3D G3DSA:3.40.630.10 25 81 1.4E-64 T 11-11-2016 AUP74_RS04860 970bb21421b2fc97be9b791584c61fcc 543 Gene3D G3DSA:3.40.630.10 281 531 1.4E-64 T 11-11-2016 AUP74_RS04860 970bb21421b2fc97be9b791584c61fcc 543 SUPERFAMILY SSF52025 113 205 3.66E-11 T 11-11-2016 AUP74_RS04860 970bb21421b2fc97be9b791584c61fcc 543 Pfam PF02225 PA domain 129 212 1.2E-6 T 11-11-2016 IPR003137 PA domain AUP74_RS04860 970bb21421b2fc97be9b791584c61fcc 543 Pfam PF04389 Peptidase family M28 296 513 5.4E-47 T 11-11-2016 IPR007484 Peptidase M28 AUP74_RS04860 970bb21421b2fc97be9b791584c61fcc 543 SUPERFAMILY SSF53187 26 75 6.8E-68 T 11-11-2016 AUP74_RS04860 970bb21421b2fc97be9b791584c61fcc 543 SUPERFAMILY SSF53187 280 523 6.8E-68 T 11-11-2016 AUP74_RS04860 970bb21421b2fc97be9b791584c61fcc 543 Gene3D G3DSA:3.50.30.30 118 215 1.2E-6 T 11-11-2016 AUP74_RS14425 69279b757b9ec176d5d09acece1b489f 314 SUPERFAMILY SSF88713 44 307 8.9E-49 T 11-11-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AUP74_RS14425 69279b757b9ec176d5d09acece1b489f 314 Gene3D G3DSA:3.20.20.370 25 306 1.1E-51 T 11-11-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 AUP74_RS14425 69279b757b9ec176d5d09acece1b489f 314 Pfam PF01522 Polysaccharide deacetylase 84 195 1.6E-11 T 11-11-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 AUP74_RS16325 3582a25be9a7d995fbfad0c057f8a93d 194 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 41 136 6.0E-17 T 11-11-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 AUP74_RS16325 3582a25be9a7d995fbfad0c057f8a93d 194 Gene3D G3DSA:3.40.140.10 41 173 1.6E-28 T 11-11-2016 AUP74_RS16325 3582a25be9a7d995fbfad0c057f8a93d 194 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 92 125 - T 11-11-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 AUP74_RS16325 3582a25be9a7d995fbfad0c057f8a93d 194 SUPERFAMILY SSF53927 40 188 1.04E-31 T 11-11-2016 IPR016193 Cytidine deaminase-like GO:0003824 AUP74_RS09980 6eca45c181950f041b3b8ae0f21c1124 477 Pfam PF13520 Amino acid permease 13 417 7.7E-61 T 11-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 AUP74_RS09980 6eca45c181950f041b3b8ae0f21c1124 477 TIGRFAM TIGR00905 2A0302: transporter, basic amino acid/polyamine antiporter (APA) family 1 477 5.1E-156 T 11-11-2016 IPR004754 Amino acid antiporter GO:0006865|GO:0016021 AUP74_RS09980 6eca45c181950f041b3b8ae0f21c1124 477 PIRSF PIRSF006060 1 471 1.6E-43 T 11-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 AUP74_RS06855 82bd296d0da49f3549d24ec32956966c 226 SUPERFAMILY SSF54821 108 206 1.01E-41 T 11-11-2016 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06855 82bd296d0da49f3549d24ec32956966c 226 Pfam PF07650 KH domain 38 110 1.0E-21 T 11-11-2016 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06855 82bd296d0da49f3549d24ec32956966c 226 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 11-11-2016 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06855 82bd296d0da49f3549d24ec32956966c 226 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 39.605 T 11-11-2016 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 AUP74_RS06855 82bd296d0da49f3549d24ec32956966c 226 Gene3D G3DSA:3.30.1140.32 108 207 1.1E-48 T 11-11-2016 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AUP74_RS06855 82bd296d0da49f3549d24ec32956966c 226 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 209 2.9E-97 T 11-11-2016 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 AUP74_RS06855 82bd296d0da49f3549d24ec32956966c 226 Pfam PF00189 Ribosomal protein S3, C-terminal domain 120 202 1.2E-41 T 11-11-2016 AUP74_RS06855 82bd296d0da49f3549d24ec32956966c 226 SMART SM00322 60 125 1.0E-10 T 11-11-2016 IPR004087 K Homology domain GO:0003676 AUP74_RS06855 82bd296d0da49f3549d24ec32956966c 226 Gene3D G3DSA:3.30.300.20 17 107 3.7E-33 T 11-11-2016 IPR015946 K homology domain-like, alpha/beta AUP74_RS06855 82bd296d0da49f3549d24ec32956966c 226 SUPERFAMILY SSF54814 2 106 1.05E-37 T 11-11-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 AUP74_RS03470 d1bb8e0cde94211c0644cdc01d4cc4a2 186 Pfam PF13505 Outer membrane protein beta-barrel domain 8 186 8.6E-10 T 11-11-2016 IPR027385 Outer membrane protein beta-barrel AUP74_RS03470 d1bb8e0cde94211c0644cdc01d4cc4a2 186 SUPERFAMILY SSF56925 39 186 6.54E-11 T 11-11-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AUP74_RS03470 d1bb8e0cde94211c0644cdc01d4cc4a2 186 Gene3D G3DSA:2.40.160.10 40 171 1.5E-7 T 11-11-2016 IPR023614 Porin domain AUP74_RS00710 b902704c40aa1db8720d9c02f0eaed7b 381 Pfam PF14559 Tetratricopeptide repeat 201 255 1.3E-5 T 11-11-2016 AUP74_RS00710 b902704c40aa1db8720d9c02f0eaed7b 381 SMART SM00028 191 224 0.11 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS00710 b902704c40aa1db8720d9c02f0eaed7b 381 SMART SM00028 293 326 32.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS00710 b902704c40aa1db8720d9c02f0eaed7b 381 SMART SM00028 225 258 0.0015 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS00710 b902704c40aa1db8720d9c02f0eaed7b 381 SMART SM00028 327 360 67.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS00710 b902704c40aa1db8720d9c02f0eaed7b 381 Pfam PF13432 Tetratricopeptide repeat 297 352 3.5E-8 T 11-11-2016 AUP74_RS00710 b902704c40aa1db8720d9c02f0eaed7b 381 Gene3D G3DSA:1.25.40.10 188 362 1.2E-27 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS00710 b902704c40aa1db8720d9c02f0eaed7b 381 SUPERFAMILY SSF54001 54 130 2.38E-7 T 11-11-2016 AUP74_RS00710 b902704c40aa1db8720d9c02f0eaed7b 381 SUPERFAMILY SSF48452 191 357 6.92E-24 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS12785 897270412e3d12defe0fd7638ac2f0fe 124 TIGRFAM TIGR00494 crcB: protein CrcB 4 119 3.6E-30 T 11-11-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 AUP74_RS12785 897270412e3d12defe0fd7638ac2f0fe 124 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 5 114 6.6E-25 T 11-11-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 AUP74_RS12785 897270412e3d12defe0fd7638ac2f0fe 124 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 121 18.938 T 11-11-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 AUP74_RS15920 ab479e235c1a88e02123d2fc81eb0f56 76 Gene3D G3DSA:2.30.30.320 2 73 1.6E-32 T 11-11-2016 IPR023387 DUF1653-like domain AUP74_RS15920 ab479e235c1a88e02123d2fc81eb0f56 76 Pfam PF07866 Protein of unknown function (DUF1653) 10 70 6.5E-30 T 11-11-2016 IPR023387 DUF1653-like domain AUP74_RS04430 4ba476832d7d4d2244b0bf0b387877dd 297 SUPERFAMILY SSF109709 122 231 1.86E-34 T 11-11-2016 AUP74_RS04430 4ba476832d7d4d2244b0bf0b387877dd 297 Gene3D G3DSA:3.90.1530.10 34 135 8.4E-40 T 11-11-2016 AUP74_RS04430 4ba476832d7d4d2244b0bf0b387877dd 297 Gene3D G3DSA:1.10.260.40 141 173 9.5E-4 T 11-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AUP74_RS04430 4ba476832d7d4d2244b0bf0b387877dd 297 SMART SM00470 40 129 1.6E-34 T 11-11-2016 IPR003115 ParB/Sulfiredoxin AUP74_RS04430 4ba476832d7d4d2244b0bf0b387877dd 297 Pfam PF02195 ParB-like nuclease domain 41 129 2.4E-26 T 11-11-2016 IPR003115 ParB/Sulfiredoxin AUP74_RS04430 4ba476832d7d4d2244b0bf0b387877dd 297 SUPERFAMILY SSF110849 40 131 2.88E-29 T 11-11-2016 IPR003115 ParB/Sulfiredoxin AUP74_RS04430 4ba476832d7d4d2244b0bf0b387877dd 297 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 36 207 2.3E-58 T 11-11-2016 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 AUP74_RS07510 29793215daacf40ae16dbb2f16039537 1055 SUPERFAMILY SSF82714 184 263 9.94E-11 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS07510 29793215daacf40ae16dbb2f16039537 1055 SUPERFAMILY SSF82866 289 488 2.62E-39 T 11-11-2016 AUP74_RS07510 29793215daacf40ae16dbb2f16039537 1055 SUPERFAMILY SSF82714 713 795 1.44E-7 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS07510 29793215daacf40ae16dbb2f16039537 1055 SUPERFAMILY SSF82693 40 130 3.4E-18 T 11-11-2016 AUP74_RS07510 29793215daacf40ae16dbb2f16039537 1055 SUPERFAMILY SSF82693 566 657 1.02E-6 T 11-11-2016 AUP74_RS07510 29793215daacf40ae16dbb2f16039537 1055 Gene3D G3DSA:3.30.2090.10 186 264 7.7E-11 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS07510 29793215daacf40ae16dbb2f16039537 1055 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 5.9E-25 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS07510 29793215daacf40ae16dbb2f16039537 1055 PRINTS PR00702 Acriflavin resistance protein family signature 460 483 5.9E-25 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS07510 29793215daacf40ae16dbb2f16039537 1055 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 5.9E-25 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS07510 29793215daacf40ae16dbb2f16039537 1055 PRINTS PR00702 Acriflavin resistance protein family signature 328 351 5.9E-25 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS07510 29793215daacf40ae16dbb2f16039537 1055 PRINTS PR00702 Acriflavin resistance protein family signature 382 406 5.9E-25 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS07510 29793215daacf40ae16dbb2f16039537 1055 PRINTS PR00702 Acriflavin resistance protein family signature 435 458 5.9E-25 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS07510 29793215daacf40ae16dbb2f16039537 1055 SUPERFAMILY SSF82693 137 180 3.92E-11 T 11-11-2016 AUP74_RS07510 29793215daacf40ae16dbb2f16039537 1055 SUPERFAMILY SSF82693 266 322 3.92E-11 T 11-11-2016 AUP74_RS07510 29793215daacf40ae16dbb2f16039537 1055 Gene3D G3DSA:3.30.70.1430 40 139 6.1E-20 T 11-11-2016 AUP74_RS07510 29793215daacf40ae16dbb2f16039537 1055 SUPERFAMILY SSF82866 798 1036 7.98E-35 T 11-11-2016 AUP74_RS07510 29793215daacf40ae16dbb2f16039537 1055 Gene3D G3DSA:3.30.2090.10 713 795 4.4E-7 T 11-11-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AUP74_RS07510 29793215daacf40ae16dbb2f16039537 1055 Gene3D G3DSA:1.10.3850.10 803 1031 4.0E-45 T 11-11-2016 AUP74_RS07510 29793215daacf40ae16dbb2f16039537 1055 Pfam PF00873 AcrB/AcrD/AcrF family 5 1031 1.6E-155 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS07510 29793215daacf40ae16dbb2f16039537 1055 Gene3D G3DSA:3.30.70.1430 566 657 1.4E-5 T 11-11-2016 AUP74_RS07510 29793215daacf40ae16dbb2f16039537 1055 Gene3D G3DSA:1.20.1640.10 283 489 2.6E-48 T 11-11-2016 AUP74_RS16065 e492ceb40323fa29f370b2faf6012125 420 Gene3D G3DSA:3.90.190.20 276 414 1.0E-30 T 11-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AUP74_RS16065 e492ceb40323fa29f370b2faf6012125 420 SUPERFAMILY SSF53623 3 269 1.06E-75 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AUP74_RS16065 e492ceb40323fa29f370b2faf6012125 420 SUPERFAMILY SSF53244 276 413 5.49E-27 T 11-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AUP74_RS16065 e492ceb40323fa29f370b2faf6012125 420 PIRSF PIRSF001563 1 417 3.7E-87 T 11-11-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 AUP74_RS16065 e492ceb40323fa29f370b2faf6012125 420 TIGRFAM TIGR01499 folC: bifunctional protein FolC 23 411 2.0E-84 T 11-11-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 AUP74_RS16065 e492ceb40323fa29f370b2faf6012125 420 Gene3D G3DSA:3.40.1190.10 4 275 3.9E-78 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AUP74_RS16065 e492ceb40323fa29f370b2faf6012125 420 Pfam PF08245 Mur ligase middle domain 45 182 5.7E-5 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 AUP74_RS09290 2391d8df02d3772f60d5dbae38cdd0eb 217 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 24 174 42.77 T 11-11-2016 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09290 2391d8df02d3772f60d5dbae38cdd0eb 217 Gene3D G3DSA:3.40.50.700 45 172 1.3E-31 T 11-11-2016 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09290 2391d8df02d3772f60d5dbae38cdd0eb 217 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 61 167 1.2E-22 T 11-11-2016 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09290 2391d8df02d3772f60d5dbae38cdd0eb 217 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 141 157 - T 11-11-2016 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09290 2391d8df02d3772f60d5dbae38cdd0eb 217 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 34 175 2.0E-69 T 11-11-2016 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09290 2391d8df02d3772f60d5dbae38cdd0eb 217 SUPERFAMILY SSF56770 32 183 1.44E-64 T 11-11-2016 AUP74_RS06600 6c456e759848a68612bea3c2c1a007b9 427 Gene3D G3DSA:3.90.1150.10 2 69 3.9E-48 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS06600 6c456e759848a68612bea3c2c1a007b9 427 Gene3D G3DSA:3.90.1150.10 319 425 3.9E-48 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS06600 6c456e759848a68612bea3c2c1a007b9 427 Gene3D G3DSA:3.40.640.10 70 316 8.2E-85 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AUP74_RS06600 6c456e759848a68612bea3c2c1a007b9 427 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 3 426 107.55 T 11-11-2016 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 AUP74_RS06600 6c456e759848a68612bea3c2c1a007b9 427 SUPERFAMILY SSF53383 1 425 1.9E-142 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase AUP74_RS06600 6c456e759848a68612bea3c2c1a007b9 427 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 234 270 - T 11-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AUP74_RS06600 6c456e759848a68612bea3c2c1a007b9 427 Pfam PF00202 Aminotransferase class-III 32 416 5.0E-80 T 11-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AUP74_RS06600 6c456e759848a68612bea3c2c1a007b9 427 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 3 425 6.6E-197 T 11-11-2016 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 AUP74_RS05490 53ed95b8b8bdf2397fb8a73c8ae682b9 344 SUPERFAMILY SSF52540 5 334 1.44E-70 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05490 53ed95b8b8bdf2397fb8a73c8ae682b9 344 Gene3D G3DSA:3.40.50.300 100 342 1.7E-70 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05490 53ed95b8b8bdf2397fb8a73c8ae682b9 344 Pfam PF00437 Type II/IV secretion system protein 11 265 8.4E-47 T 11-11-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 AUP74_RS05490 53ed95b8b8bdf2397fb8a73c8ae682b9 344 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 3 342 2.1E-153 T 11-11-2016 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 AUP74_RS05490 53ed95b8b8bdf2397fb8a73c8ae682b9 344 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 193 207 - T 11-11-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 AUP74_RS05490 53ed95b8b8bdf2397fb8a73c8ae682b9 344 SMART SM00382 122 256 0.0068 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS01000 27c7b4f4955ed40c929ffe01450271e4 305 Gene3D G3DSA:3.40.50.1820 10 305 1.1E-64 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS01000 27c7b4f4955ed40c929ffe01450271e4 305 SUPERFAMILY SSF53474 192 305 3.33E-44 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS01000 27c7b4f4955ed40c929ffe01450271e4 305 SUPERFAMILY SSF53474 11 141 3.33E-44 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS01000 27c7b4f4955ed40c929ffe01450271e4 305 Pfam PF12697 Alpha/beta hydrolase family 41 287 5.0E-8 T 11-11-2016 IPR000073 Alpha/beta hydrolase fold-1 AUP74_RS02120 82c31a867769fbcc48d88726e3abfc2e 196 Gene3D G3DSA:3.40.630.30 22 170 1.2E-15 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS02120 82c31a867769fbcc48d88726e3abfc2e 196 Pfam PF00583 Acetyltransferase (GNAT) family 87 161 8.3E-10 T 11-11-2016 IPR000182 GNAT domain GO:0008080 AUP74_RS02120 82c31a867769fbcc48d88726e3abfc2e 196 SUPERFAMILY SSF55729 20 170 1.44E-17 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS08010 1b68afcc566c98aa09140ee63bc96a1c 197 SUPERFAMILY SSF46894 126 189 2.24E-18 T 11-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AUP74_RS08010 1b68afcc566c98aa09140ee63bc96a1c 197 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 176 3.9E-12 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS08010 1b68afcc566c98aa09140ee63bc96a1c 197 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 134 148 3.9E-12 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS08010 1b68afcc566c98aa09140ee63bc96a1c 197 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 164 3.9E-12 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS08010 1b68afcc566c98aa09140ee63bc96a1c 197 SMART SM00421 131 188 4.7E-19 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS08010 1b68afcc566c98aa09140ee63bc96a1c 197 ProSitePatterns PS00622 LuxR-type HTH domain signature. 148 175 - T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS08010 1b68afcc566c98aa09140ee63bc96a1c 197 Gene3D G3DSA:1.10.10.10 117 189 2.2E-21 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS08010 1b68afcc566c98aa09140ee63bc96a1c 197 Pfam PF00196 Bacterial regulatory proteins, luxR family 134 188 2.5E-19 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS15490 b1380516f995f69ae38ee6653f34755b 295 SUPERFAMILY SSF50156 204 272 3.15E-13 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS15490 b1380516f995f69ae38ee6653f34755b 295 Gene3D G3DSA:2.30.42.10 199 271 1.7E-14 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS15490 b1380516f995f69ae38ee6653f34755b 295 Pfam PF13180 PDZ domain 202 264 8.2E-10 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS15490 b1380516f995f69ae38ee6653f34755b 295 SMART SM00228 192 261 0.0046 T 11-11-2016 IPR001478 PDZ domain GO:0005515 AUP74_RS10380 e09b2f8b3f116bd067d79427070fae53 220 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 12 32 1.0E-7 T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS10380 e09b2f8b3f116bd067d79427070fae53 220 Pfam PF13633 Prokaryotic N-terminal methylation site 11 36 4.0E-9 T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS10380 e09b2f8b3f116bd067d79427070fae53 220 Gene3D G3DSA:3.30.700.10 13 79 4.5E-4 T 11-11-2016 AUP74_RS10380 e09b2f8b3f116bd067d79427070fae53 220 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 11 31 - T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS10380 e09b2f8b3f116bd067d79427070fae53 220 Pfam PF12019 Type II transport protein GspH 48 185 8.5E-6 T 11-11-2016 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 AUP74_RS10380 e09b2f8b3f116bd067d79427070fae53 220 SUPERFAMILY SSF54523 13 109 1.26E-16 T 11-11-2016 AUP74_RS01665 f31dac79f21ac2eba56cc66de82c9fce 345 SMART SM00342 247 329 6.3E-18 T 11-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AUP74_RS01665 f31dac79f21ac2eba56cc66de82c9fce 345 Gene3D G3DSA:1.10.10.60 282 331 4.4E-11 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS01665 f31dac79f21ac2eba56cc66de82c9fce 345 SUPERFAMILY SSF46689 282 332 2.8E-10 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS01665 f31dac79f21ac2eba56cc66de82c9fce 345 Pfam PF12833 Helix-turn-helix domain 257 330 5.5E-14 T 11-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AUP74_RS01665 f31dac79f21ac2eba56cc66de82c9fce 345 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 21 205 1.1E-32 T 11-11-2016 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal AUP74_RS05620 5473d187ac0309dcf62aab4cf96769a1 163 Pfam PF13420 Acetyltransferase (GNAT) domain 2 153 2.2E-20 T 11-11-2016 AUP74_RS05620 5473d187ac0309dcf62aab4cf96769a1 163 Gene3D G3DSA:3.40.630.30 1 162 1.7E-36 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS05620 5473d187ac0309dcf62aab4cf96769a1 163 SUPERFAMILY SSF55729 1 162 7.5E-28 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS15085 59bf55f1f001d352a8d8cae787819bf3 87 Gene3D G3DSA:3.40.50.1820 6 81 3.9E-8 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS15085 59bf55f1f001d352a8d8cae787819bf3 87 SUPERFAMILY SSF53474 5 53 1.05E-6 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS15085 59bf55f1f001d352a8d8cae787819bf3 87 Pfam PF01738 Dienelactone hydrolase family 7 81 3.6E-4 T 11-11-2016 IPR002925 Dienelactone hydrolase GO:0016787 AUP74_RS13995 d29a46953a03b67104c0d08f07c77b06 466 SUPERFAMILY SSF54001 307 415 1.47E-18 T 11-11-2016 AUP74_RS13995 d29a46953a03b67104c0d08f07c77b06 466 PIRSF PIRSF019015 25 466 2.2E-87 T 11-11-2016 IPR027017 Uncharacterised peptidase with NlpC/P60 domain, YkfC type AUP74_RS13995 d29a46953a03b67104c0d08f07c77b06 466 Pfam PF12913 SH3 domain (SH3b1 type) 162 209 1.7E-10 T 11-11-2016 AUP74_RS13995 d29a46953a03b67104c0d08f07c77b06 466 Gene3D G3DSA:3.90.1720.10 308 420 2.0E-21 T 11-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain AUP74_RS13995 d29a46953a03b67104c0d08f07c77b06 466 Pfam PF00877 NlpC/P60 family 328 418 1.5E-13 T 11-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain AUP74_RS03600 548c41cbc6b04f792e5623dd50ef86bc 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 226 1.3E-19 T 11-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AUP74_RS03600 548c41cbc6b04f792e5623dd50ef86bc 233 Gene3D G3DSA:1.10.10.10 130 227 9.4E-28 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS03600 548c41cbc6b04f792e5623dd50ef86bc 233 SUPERFAMILY SSF52172 4 185 1.93E-33 T 11-11-2016 IPR011006 CheY-like superfamily AUP74_RS03600 548c41cbc6b04f792e5623dd50ef86bc 233 Pfam PF00072 Response regulator receiver domain 8 116 5.5E-20 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS03600 548c41cbc6b04f792e5623dd50ef86bc 233 SMART SM00448 6 116 1.0E-29 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS03600 548c41cbc6b04f792e5623dd50ef86bc 233 SMART SM00862 151 226 3.8E-19 T 11-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AUP74_RS03600 548c41cbc6b04f792e5623dd50ef86bc 233 Gene3D G3DSA:3.40.50.2300 5 126 2.1E-30 T 11-11-2016 AUP74_RS15685 7441e0500483784715324677d92786cf 344 Pfam PF14790 Tetrahydrodipicolinate N-succinyltransferase N-terminal 85 131 3.2E-7 T 11-11-2016 AUP74_RS15685 7441e0500483784715324677d92786cf 344 SUPERFAMILY SSF51161 95 292 1.36E-35 T 11-11-2016 IPR011004 Trimeric LpxA-like AUP74_RS15685 7441e0500483784715324677d92786cf 344 TIGRFAM TIGR03536 DapD_gpp: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 5 344 2.4E-180 T 11-11-2016 IPR019876 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, gammaproteobacteria KEGG: 00300+2.3.1.117 AUP74_RS15685 7441e0500483784715324677d92786cf 344 Hamap MF_02122 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 4 342 44.096 T 11-11-2016 IPR026586 Type 2 tetrahydrodipicolinate N-succinyltransferase family GO:0008666 KEGG: 00300+2.3.1.117 AUP74_RS15685 7441e0500483784715324677d92786cf 344 Pfam PF14789 Tetrahydrodipicolinate N-succinyltransferase middle 133 173 2.4E-14 T 11-11-2016 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 AUP74_RS15685 7441e0500483784715324677d92786cf 344 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 255 287 1.6E-15 T 11-11-2016 IPR001451 Hexapeptide repeat AUP74_RS15685 7441e0500483784715324677d92786cf 344 Gene3D G3DSA:3.30.60.70 133 173 9.0E-19 T 11-11-2016 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 AUP74_RS15685 7441e0500483784715324677d92786cf 344 Gene3D G3DSA:2.160.10.10 174 342 1.4E-32 T 11-11-2016 AUP74_RS00480 d987b1d6df4e8d592a823150996e2a48 244 SUPERFAMILY SSF51695 9 234 4.45E-49 T 11-11-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 AUP74_RS00480 d987b1d6df4e8d592a823150996e2a48 244 Gene3D G3DSA:3.20.20.190 9 234 4.8E-45 T 11-11-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 AUP74_RS00480 d987b1d6df4e8d592a823150996e2a48 244 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 12 228 3.6E-21 T 11-11-2016 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 AUP74_RS11335 b36a2e3abb1a8c8ade6a43b0808046d4 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 89 102 1.3E-10 T 11-11-2016 IPR000073 Alpha/beta hydrolase fold-1 AUP74_RS11335 b36a2e3abb1a8c8ade6a43b0808046d4 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 206 220 1.3E-10 T 11-11-2016 IPR000073 Alpha/beta hydrolase fold-1 AUP74_RS11335 b36a2e3abb1a8c8ade6a43b0808046d4 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 103 116 1.3E-10 T 11-11-2016 IPR000073 Alpha/beta hydrolase fold-1 AUP74_RS11335 b36a2e3abb1a8c8ade6a43b0808046d4 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 45 60 1.3E-10 T 11-11-2016 IPR000073 Alpha/beta hydrolase fold-1 AUP74_RS11335 b36a2e3abb1a8c8ade6a43b0808046d4 274 Pfam PF00561 alpha/beta hydrolase fold 20 248 1.6E-27 T 11-11-2016 IPR000073 Alpha/beta hydrolase fold-1 AUP74_RS11335 b36a2e3abb1a8c8ade6a43b0808046d4 274 Gene3D G3DSA:3.40.50.1820 3 262 1.2E-67 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS11335 b36a2e3abb1a8c8ade6a43b0808046d4 274 PRINTS PR00412 Epoxide hydrolase signature 237 259 2.5E-5 T 11-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 AUP74_RS11335 b36a2e3abb1a8c8ade6a43b0808046d4 274 PRINTS PR00412 Epoxide hydrolase signature 26 44 2.5E-5 T 11-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 AUP74_RS11335 b36a2e3abb1a8c8ade6a43b0808046d4 274 PRINTS PR00412 Epoxide hydrolase signature 103 116 2.5E-5 T 11-11-2016 IPR000639 Epoxide hydrolase-like GO:0003824 AUP74_RS11335 b36a2e3abb1a8c8ade6a43b0808046d4 274 SUPERFAMILY SSF53474 3 261 8.32E-70 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS10075 465ae5bb2cb910582fbd33b2f857ace4 428 Hamap MF_00318 Enolase [eno]. 2 415 44.209 T 11-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AUP74_RS10075 465ae5bb2cb910582fbd33b2f857ace4 428 Pfam PF03952 Enolase, N-terminal domain 4 134 1.2E-58 T 11-11-2016 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AUP74_RS10075 465ae5bb2cb910582fbd33b2f857ace4 428 SUPERFAMILY SSF51604 143 426 4.45E-129 T 11-11-2016 IPR029065 Enolase C-terminal domain-like AUP74_RS10075 465ae5bb2cb910582fbd33b2f857ace4 428 ProSitePatterns PS00164 Enolase signature. 338 351 - T 11-11-2016 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS10075 465ae5bb2cb910582fbd33b2f857ace4 428 Gene3D G3DSA:3.20.20.120 128 427 2.0E-134 T 11-11-2016 IPR029065 Enolase C-terminal domain-like AUP74_RS10075 465ae5bb2cb910582fbd33b2f857ace4 428 Gene3D G3DSA:3.30.390.10 3 126 1.6E-53 T 11-11-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AUP74_RS10075 465ae5bb2cb910582fbd33b2f857ace4 428 SUPERFAMILY SSF54826 3 137 2.42E-56 T 11-11-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AUP74_RS10075 465ae5bb2cb910582fbd33b2f857ace4 428 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 427 8.3E-207 T 11-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AUP74_RS10075 465ae5bb2cb910582fbd33b2f857ace4 428 SMART SM01192 143 428 3.7E-219 T 11-11-2016 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AUP74_RS10075 465ae5bb2cb910582fbd33b2f857ace4 428 PRINTS PR00148 Enolase signature 338 352 8.7E-44 T 11-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AUP74_RS10075 465ae5bb2cb910582fbd33b2f857ace4 428 PRINTS PR00148 Enolase signature 367 384 8.7E-44 T 11-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AUP74_RS10075 465ae5bb2cb910582fbd33b2f857ace4 428 PRINTS PR00148 Enolase signature 165 178 8.7E-44 T 11-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AUP74_RS10075 465ae5bb2cb910582fbd33b2f857ace4 428 PRINTS PR00148 Enolase signature 37 51 8.7E-44 T 11-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AUP74_RS10075 465ae5bb2cb910582fbd33b2f857ace4 428 PRINTS PR00148 Enolase signature 315 326 8.7E-44 T 11-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AUP74_RS10075 465ae5bb2cb910582fbd33b2f857ace4 428 PRINTS PR00148 Enolase signature 107 123 8.7E-44 T 11-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AUP74_RS10075 465ae5bb2cb910582fbd33b2f857ace4 428 Pfam PF00113 Enolase, C-terminal TIM barrel domain 144 426 3.9E-136 T 11-11-2016 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AUP74_RS10075 465ae5bb2cb910582fbd33b2f857ace4 428 SMART SM01193 4 134 4.1E-94 T 11-11-2016 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AUP74_RS10075 465ae5bb2cb910582fbd33b2f857ace4 428 PIRSF PIRSF001400 1 428 4.5E-192 T 11-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AUP74_RS05465 08a378343e0a963d8206715185bf691b 108 SUPERFAMILY SSF55387 5 106 5.41E-24 T 11-11-2016 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 AUP74_RS05465 08a378343e0a963d8206715185bf691b 108 Pfam PF01491 Frataxin-like domain 4 103 6.6E-18 T 11-11-2016 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 AUP74_RS05465 08a378343e0a963d8206715185bf691b 108 Gene3D G3DSA:3.30.920.10 5 106 1.7E-21 T 11-11-2016 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 AUP74_RS05465 08a378343e0a963d8206715185bf691b 108 SMART SM01219 3 107 3.3E-31 T 11-11-2016 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 AUP74_RS05465 08a378343e0a963d8206715185bf691b 108 TIGRFAM TIGR03421 FeS_CyaY: iron donor protein CyaY 5 105 2.7E-28 T 11-11-2016 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 AUP74_RS05465 08a378343e0a963d8206715185bf691b 108 Hamap MF_00142 Protein CyaY [cyaY]. 1 106 20.7 T 11-11-2016 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 AUP74_RS05465 08a378343e0a963d8206715185bf691b 108 ProSitePatterns PS01344 Frataxin family signature. 51 65 - T 11-11-2016 IPR020895 Frataxin conserved site Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 AUP74_RS15395 5950ea09cc34e080484c729943681a77 244 Pfam PF00246 Zinc carboxypeptidase 34 156 6.5E-11 T 11-11-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 AUP74_RS15395 5950ea09cc34e080484c729943681a77 244 Gene3D G3DSA:3.40.630.10 17 215 3.8E-36 T 11-11-2016 AUP74_RS15395 5950ea09cc34e080484c729943681a77 244 SUPERFAMILY SSF53187 17 106 1.75E-31 T 11-11-2016 AUP74_RS15395 5950ea09cc34e080484c729943681a77 244 SUPERFAMILY SSF53187 133 213 1.75E-31 T 11-11-2016 AUP74_RS03445 db03a9c67a2fd762bbea0151e51096f5 184 TIGRFAM TIGR01383 not_thiJ: DJ-1 family protein 3 180 1.9E-55 T 11-11-2016 IPR006287 Protein deglycase DJ-1 GO:0006517|GO:0030091 AUP74_RS03445 db03a9c67a2fd762bbea0151e51096f5 184 Pfam PF01965 DJ-1/PfpI family 2 167 1.8E-40 T 11-11-2016 IPR002818 DJ-1/PfpI AUP74_RS03445 db03a9c67a2fd762bbea0151e51096f5 184 SUPERFAMILY SSF52317 1 182 2.18E-44 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS03445 db03a9c67a2fd762bbea0151e51096f5 184 Gene3D G3DSA:3.40.50.880 1 183 1.8E-50 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS02975 928f226d8929d38bbece47dfd96ba25b 336 Gene3D G3DSA:3.40.50.720 1 163 8.1E-63 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS02975 928f226d8929d38bbece47dfd96ba25b 336 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 155 1.3E-53 T 11-11-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS02975 928f226d8929d38bbece47dfd96ba25b 336 Gene3D G3DSA:3.30.360.10 164 319 7.0E-61 T 11-11-2016 AUP74_RS02975 928f226d8929d38bbece47dfd96ba25b 336 PIRSF PIRSF000149 1 336 3.5E-133 T 11-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS02975 928f226d8929d38bbece47dfd96ba25b 336 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 161 316 8.4E-52 T 11-11-2016 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS02975 928f226d8929d38bbece47dfd96ba25b 336 SMART SM00846 3 155 2.6E-79 T 11-11-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS02975 928f226d8929d38bbece47dfd96ba25b 336 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 329 2.4E-111 T 11-11-2016 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS02975 928f226d8929d38bbece47dfd96ba25b 336 SUPERFAMILY SSF55347 155 318 1.9E-57 T 11-11-2016 AUP74_RS02975 928f226d8929d38bbece47dfd96ba25b 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 233 250 1.9E-29 T 11-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS02975 928f226d8929d38bbece47dfd96ba25b 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 149 167 1.9E-29 T 11-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS02975 928f226d8929d38bbece47dfd96ba25b 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 176 192 1.9E-29 T 11-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS02975 928f226d8929d38bbece47dfd96ba25b 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 112 125 1.9E-29 T 11-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS02975 928f226d8929d38bbece47dfd96ba25b 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 273 288 1.9E-29 T 11-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS02975 928f226d8929d38bbece47dfd96ba25b 336 SUPERFAMILY SSF51735 1 181 9.44E-57 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS13305 013bac7d670502ceddc851afe5a2a7b1 407 Pfam PF02515 CoA-transferase family III 5 383 5.6E-130 T 11-11-2016 IPR003673 CoA-transferase family III GO:0003824 AUP74_RS13305 013bac7d670502ceddc851afe5a2a7b1 407 Gene3D G3DSA:3.40.50.10540 2 227 4.9E-120 T 11-11-2016 IPR023606 CoA-transferase family III domain AUP74_RS13305 013bac7d670502ceddc851afe5a2a7b1 407 Gene3D G3DSA:3.40.50.10540 316 407 4.9E-120 T 11-11-2016 IPR023606 CoA-transferase family III domain AUP74_RS13305 013bac7d670502ceddc851afe5a2a7b1 407 Gene3D G3DSA:3.30.1540.10 233 315 8.6E-31 T 11-11-2016 AUP74_RS13305 013bac7d670502ceddc851afe5a2a7b1 407 SUPERFAMILY SSF89796 3 407 5.23E-142 T 11-11-2016 IPR023606 CoA-transferase family III domain AUP74_RS13770 977b2b86e3b4b9652f9d2850962c7d71 68 Pfam PF11146 Protein of unknown function (DUF2905) 3 66 6.5E-22 T 11-11-2016 IPR021320 Protein of unknown function DUF2905 AUP74_RS16710 62801ba5e4f8b15480a5db362eeae098 303 Gene3D G3DSA:3.30.230.20 3 125 2.0E-47 T 11-11-2016 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 AUP74_RS16710 62801ba5e4f8b15480a5db362eeae098 303 Gene3D G3DSA:3.30.1700.10 128 282 2.2E-60 T 11-11-2016 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 AUP74_RS16710 62801ba5e4f8b15480a5db362eeae098 303 Hamap MF_00388 UDP-3-O-acyl-N-acetylglucosamine deacetylase [lpxC]. 2 279 46.895 T 11-11-2016 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 AUP74_RS16710 62801ba5e4f8b15480a5db362eeae098 303 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 4 275 2.0E-108 T 11-11-2016 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 AUP74_RS16710 62801ba5e4f8b15480a5db362eeae098 303 SUPERFAMILY SSF54211 3 125 7.59E-43 T 11-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold AUP74_RS16710 62801ba5e4f8b15480a5db362eeae098 303 SUPERFAMILY SSF54211 133 277 3.94E-52 T 11-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold AUP74_RS16710 62801ba5e4f8b15480a5db362eeae098 303 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 2 298 2.3E-125 T 11-11-2016 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 AUP74_RS00475 35ecb5b11bbd1df37b5f44d7435c699f 171 SUPERFAMILY SSF50475 15 167 5.23E-51 T 11-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 AUP74_RS00475 35ecb5b11bbd1df37b5f44d7435c699f 171 Pfam PF01613 Flavin reductase like domain 24 167 1.6E-39 T 11-11-2016 IPR002563 Flavin reductase like domain GO:0010181 AUP74_RS00475 35ecb5b11bbd1df37b5f44d7435c699f 171 SMART SM00903 23 166 1.1E-60 T 11-11-2016 IPR002563 Flavin reductase like domain GO:0010181 AUP74_RS00475 35ecb5b11bbd1df37b5f44d7435c699f 171 Gene3D G3DSA:2.30.110.10 11 165 1.7E-57 T 11-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 AUP74_RS14365 eb83d2c10e63e1d745e55ec3ab6a0b06 371 SUPERFAMILY SSF89796 3 364 8.37E-107 T 11-11-2016 IPR023606 CoA-transferase family III domain AUP74_RS14365 eb83d2c10e63e1d745e55ec3ab6a0b06 371 Gene3D G3DSA:3.40.50.10540 298 364 1.2E-94 T 11-11-2016 IPR023606 CoA-transferase family III domain AUP74_RS14365 eb83d2c10e63e1d745e55ec3ab6a0b06 371 Gene3D G3DSA:3.40.50.10540 3 212 1.2E-94 T 11-11-2016 IPR023606 CoA-transferase family III domain AUP74_RS14365 eb83d2c10e63e1d745e55ec3ab6a0b06 371 Pfam PF02515 CoA-transferase family III 3 361 1.4E-103 T 11-11-2016 IPR003673 CoA-transferase family III GO:0003824 AUP74_RS14365 eb83d2c10e63e1d745e55ec3ab6a0b06 371 Gene3D G3DSA:3.30.1540.10 227 297 8.2E-9 T 11-11-2016 AUP74_RS00745 5a9b919a8ab900767beef2b6c50c0f8e 435 Pfam PF01943 Polysaccharide biosynthesis protein 17 277 2.9E-8 T 11-11-2016 IPR002797 Polysaccharide biosynthesis protein GO:0016020 AUP74_RS03940 d4b413c469d1746c0a4dc9ff5f4ab8fd 228 Pfam PF00005 ABC transporter 20 165 7.9E-33 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AUP74_RS03940 d4b413c469d1746c0a4dc9ff5f4ab8fd 228 Gene3D G3DSA:3.40.50.300 1 221 2.4E-67 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03940 d4b413c469d1746c0a4dc9ff5f4ab8fd 228 SUPERFAMILY SSF52540 1 222 7.5E-66 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03940 d4b413c469d1746c0a4dc9ff5f4ab8fd 228 SMART SM00382 27 213 8.2E-13 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS03940 d4b413c469d1746c0a4dc9ff5f4ab8fd 228 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AUP74_RS03940 d4b413c469d1746c0a4dc9ff5f4ab8fd 228 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 214 5.0E-87 T 11-11-2016 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 AUP74_RS09375 a1c1ebda743fcdcf049a62207e21f774 147 Gene3D G3DSA:1.10.287.70 46 136 1.4E-12 T 11-11-2016 AUP74_RS09375 a1c1ebda743fcdcf049a62207e21f774 147 Pfam PF07885 Ion channel 54 134 8.3E-12 T 11-11-2016 IPR013099 Potassium channel domain AUP74_RS09375 a1c1ebda743fcdcf049a62207e21f774 147 SUPERFAMILY SSF81324 25 136 2.75E-15 T 11-11-2016 AUP74_RS07795 8a1baa929628fef88e433f659a85438e 372 SUPERFAMILY SSF52540 108 358 6.08E-55 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS07795 8a1baa929628fef88e433f659a85438e 372 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 106 352 3.8E-97 T 11-11-2016 IPR019591 Mrp/NBP35 ATP-binding protein AUP74_RS07795 8a1baa929628fef88e433f659a85438e 372 Gene3D G3DSA:3.40.50.300 101 352 1.6E-100 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS07795 8a1baa929628fef88e433f659a85438e 372 Hamap MF_02040 Iron-sulfur cluster carrier protein. 101 354 36.958 T 11-11-2016 IPR019591 Mrp/NBP35 ATP-binding protein AUP74_RS06355 3ad0f9115fe21cffb2ae788565ce7a1c 402 SUPERFAMILY SSF47384 186 263 1.47E-8 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS06355 3ad0f9115fe21cffb2ae788565ce7a1c 402 Pfam PF00672 HAMP domain 129 199 4.5E-7 T 11-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 AUP74_RS06355 3ad0f9115fe21cffb2ae788565ce7a1c 402 SUPERFAMILY SSF55874 269 385 1.12E-8 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS06355 3ad0f9115fe21cffb2ae788565ce7a1c 402 Gene3D G3DSA:3.30.565.10 264 384 2.6E-5 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS06355 3ad0f9115fe21cffb2ae788565ce7a1c 402 Gene3D G3DSA:1.10.287.130 195 261 1.6E-5 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AUP74_RS04935 ad3ad624deb2b5d6a9e03a9543ed9634 543 SUPERFAMILY SSF111283 42 536 3.01E-95 T 11-11-2016 AUP74_RS04935 ad3ad624deb2b5d6a9e03a9543ed9634 543 Pfam PF01523 Putative modulator of DNA gyrase 59 384 4.5E-56 T 11-11-2016 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 AUP74_RS16920 ca6efbc803504301cc3fbc54b7846e6f 205 PIRSF PIRSF004649 1 204 1.5E-51 T 11-11-2016 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC AUP74_RS16920 ca6efbc803504301cc3fbc54b7846e6f 205 Gene3D G3DSA:3.10.450.50 26 70 7.0E-15 T 11-11-2016 IPR032710 NTF2-like domain AUP74_RS16920 ca6efbc803504301cc3fbc54b7846e6f 205 Gene3D G3DSA:3.10.450.50 114 168 7.0E-15 T 11-11-2016 IPR032710 NTF2-like domain AUP74_RS16920 ca6efbc803504301cc3fbc54b7846e6f 205 Gene3D G3DSA:1.10.10.640 169 198 1.8E-17 T 11-11-2016 IPR023094 Toluene tolerance protein, alpha-helical AUP74_RS16920 ca6efbc803504301cc3fbc54b7846e6f 205 Gene3D G3DSA:1.10.10.640 71 111 1.8E-17 T 11-11-2016 IPR023094 Toluene tolerance protein, alpha-helical AUP74_RS16920 ca6efbc803504301cc3fbc54b7846e6f 205 Pfam PF05494 MlaC protein 34 196 3.1E-38 T 11-11-2016 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC AUP74_RS07430 df62727b446ac04ee5c4a0a44c8647d2 176 Pfam PF13527 Acetyltransferase (GNAT) domain 5 130 1.4E-11 T 11-11-2016 AUP74_RS07430 df62727b446ac04ee5c4a0a44c8647d2 176 SUPERFAMILY SSF55729 5 137 3.09E-24 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS07430 df62727b446ac04ee5c4a0a44c8647d2 176 Gene3D G3DSA:3.40.630.30 3 151 4.7E-22 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS08865 3853c28f6359240be7859fb1405ff891 470 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 23 470 6.6E-140 T 11-11-2016 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase AUP74_RS08865 3853c28f6359240be7859fb1405ff891 470 TIGRFAM TIGR03023 WcaJ_sugtrans: undecaprenyl-phosphate glucose phosphotransferase 32 470 1.5E-157 T 11-11-2016 IPR017473 Undecaprenyl-phosphate glucose phosphotransferase, WcaJ MetaCyc: PWY-6655|MetaCyc: PWY-6658 AUP74_RS08865 3853c28f6359240be7859fb1405ff891 470 Pfam PF02397 Bacterial sugar transferase 280 461 2.0E-57 T 11-11-2016 IPR003362 Bacterial sugar transferase AUP74_RS08865 3853c28f6359240be7859fb1405ff891 470 Pfam PF13727 CoA-binding domain 61 242 1.0E-33 T 11-11-2016 AUP74_RS13470 b8350e49f8a2e623cb318275956fddee 381 Pfam PF00144 Beta-lactamase 18 371 3.8E-58 T 11-11-2016 IPR001466 Beta-lactamase-related AUP74_RS13470 b8350e49f8a2e623cb318275956fddee 381 Gene3D G3DSA:3.40.710.10 7 379 1.8E-69 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS13470 b8350e49f8a2e623cb318275956fddee 381 SUPERFAMILY SSF56601 7 378 6.47E-61 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS16355 313456cdc7f0e05c172b0634062094f1 179 Pfam PF00877 NlpC/P60 family 63 167 5.6E-33 T 11-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain AUP74_RS16355 313456cdc7f0e05c172b0634062094f1 179 Gene3D G3DSA:3.90.1720.10 50 168 1.3E-43 T 11-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain AUP74_RS16355 313456cdc7f0e05c172b0634062094f1 179 SUPERFAMILY SSF54001 46 168 2.09E-42 T 11-11-2016 AUP74_RS12585 167401aa9d8c323dd04c0a960d20e933 106 Pfam PF02656 Domain of unknown function (DUF202) 7 68 6.3E-14 T 11-11-2016 IPR003807 Domain of unknown function DUF202 AUP74_RS02290 f5f0d2dff475d4634836a71f56d0b97c 294 Pfam PF00756 Putative esterase 45 238 2.6E-17 T 11-11-2016 IPR000801 Putative esterase Reactome: R-HSA-156590 AUP74_RS02290 f5f0d2dff475d4634836a71f56d0b97c 294 SUPERFAMILY SSF53474 28 289 1.4E-54 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS02290 f5f0d2dff475d4634836a71f56d0b97c 294 Gene3D G3DSA:3.40.50.1820 43 289 2.5E-66 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS15870 2221c583e5e4b7f87282aa33ffa1df41 237 Gene3D G3DSA:3.40.50.1820 34 225 7.4E-23 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS15870 2221c583e5e4b7f87282aa33ffa1df41 237 Pfam PF01674 Lipase (class 2) 32 221 4.1E-18 T 11-11-2016 IPR002918 Lipase EstA/Esterase EstB GO:0016787 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 AUP74_RS15870 2221c583e5e4b7f87282aa33ffa1df41 237 SUPERFAMILY SSF53474 33 224 5.79E-19 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS04820 1d3990295414d8c64197e2db8409149a 217 Pfam PF00034 Cytochrome c 144 215 7.8E-9 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS04820 1d3990295414d8c64197e2db8409149a 217 Pfam PF00034 Cytochrome c 35 103 1.6E-6 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS04820 1d3990295414d8c64197e2db8409149a 217 SUPERFAMILY SSF46626 15 103 2.13E-20 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS04820 1d3990295414d8c64197e2db8409149a 217 Gene3D G3DSA:1.10.760.10 26 104 4.5E-25 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS04820 1d3990295414d8c64197e2db8409149a 217 SUPERFAMILY SSF46626 143 215 1.18E-20 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS04820 1d3990295414d8c64197e2db8409149a 217 PIRSF PIRSF000005 2 217 1.6E-58 T 11-11-2016 IPR024167 Cytochrome c4 GO:0005506|GO:0009055|GO:0020037|GO:0042597 AUP74_RS04820 1d3990295414d8c64197e2db8409149a 217 Gene3D G3DSA:1.10.760.10 132 215 8.5E-29 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS15695 5e7d2ea9e90d1fa5a5b618e127c60d0e 646 Gene3D G3DSA:3.40.50.1820 270 281 2.1E-75 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS15695 5e7d2ea9e90d1fa5a5b618e127c60d0e 646 Gene3D G3DSA:3.40.50.1820 331 636 2.1E-75 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS15695 5e7d2ea9e90d1fa5a5b618e127c60d0e 646 Pfam PF00326 Prolyl oligopeptidase family 427 637 6.7E-48 T 11-11-2016 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 AUP74_RS15695 5e7d2ea9e90d1fa5a5b618e127c60d0e 646 SUPERFAMILY SSF53474 384 636 3.44E-64 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS15695 5e7d2ea9e90d1fa5a5b618e127c60d0e 646 SUPERFAMILY SSF82171 26 384 4.32E-12 T 11-11-2016 AUP74_RS15695 5e7d2ea9e90d1fa5a5b618e127c60d0e 646 Gene3D G3DSA:2.120.10.30 27 269 2.3E-4 T 11-11-2016 IPR011042 Six-bladed beta-propeller, TolB-like AUP74_RS07870 0818c35df8d38a7dfdaf6fe916f72b2f 656 Pfam PF12228 Protein of unknown function (DUF3604) 77 652 1.3E-220 T 11-11-2016 IPR022028 Protein of unknown function DUF3604 AUP74_RS07870 0818c35df8d38a7dfdaf6fe916f72b2f 656 SUPERFAMILY SSF89550 80 163 7.65E-7 T 11-11-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AUP74_RS07870 0818c35df8d38a7dfdaf6fe916f72b2f 656 SUPERFAMILY SSF89550 199 244 7.65E-7 T 11-11-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AUP74_RS08530 0fc0a16e4ec792b344d22a6940c5afd7 646 Gene3D G3DSA:3.40.50.1700 415 635 8.2E-66 T 11-11-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 AUP74_RS08530 0fc0a16e4ec792b344d22a6940c5afd7 646 SUPERFAMILY SSF51445 47 428 3.47E-115 T 11-11-2016 IPR017853 Glycoside hydrolase superfamily AUP74_RS08530 0fc0a16e4ec792b344d22a6940c5afd7 646 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 310 327 - T 11-11-2016 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 AUP74_RS08530 0fc0a16e4ec792b344d22a6940c5afd7 646 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 430 636 8.0E-43 T 11-11-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 AUP74_RS08530 0fc0a16e4ec792b344d22a6940c5afd7 646 SUPERFAMILY SSF52279 430 636 1.31E-55 T 11-11-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 AUP74_RS08530 0fc0a16e4ec792b344d22a6940c5afd7 646 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 62 387 2.6E-83 T 11-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AUP74_RS08530 0fc0a16e4ec792b344d22a6940c5afd7 646 Gene3D G3DSA:3.20.20.300 46 401 1.8E-122 T 11-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AUP74_RS08530 0fc0a16e4ec792b344d22a6940c5afd7 646 PRINTS PR00133 Glycosyl hydrolase family 3 signature 310 328 5.7E-27 T 11-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AUP74_RS08530 0fc0a16e4ec792b344d22a6940c5afd7 646 PRINTS PR00133 Glycosyl hydrolase family 3 signature 192 208 5.7E-27 T 11-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AUP74_RS08530 0fc0a16e4ec792b344d22a6940c5afd7 646 PRINTS PR00133 Glycosyl hydrolase family 3 signature 233 249 5.7E-27 T 11-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AUP74_RS08530 0fc0a16e4ec792b344d22a6940c5afd7 646 PRINTS PR00133 Glycosyl hydrolase family 3 signature 122 138 5.7E-27 T 11-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AUP74_RS08530 0fc0a16e4ec792b344d22a6940c5afd7 646 PRINTS PR00133 Glycosyl hydrolase family 3 signature 146 165 5.7E-27 T 11-11-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AUP74_RS02635 0b60ba29cbfe2bbf038515fc55ac0988 307 SUPERFAMILY SSF53850 105 306 3.98E-25 T 11-11-2016 AUP74_RS02635 0b60ba29cbfe2bbf038515fc55ac0988 307 SUPERFAMILY SSF46785 15 100 5.45E-18 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS02635 0b60ba29cbfe2bbf038515fc55ac0988 307 Pfam PF03466 LysR substrate binding domain 107 305 2.6E-22 T 11-11-2016 IPR005119 LysR, substrate-binding AUP74_RS02635 0b60ba29cbfe2bbf038515fc55ac0988 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 17 76 2.0E-15 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS02635 0b60ba29cbfe2bbf038515fc55ac0988 307 Gene3D G3DSA:3.40.190.10 95 201 3.9E-11 T 11-11-2016 AUP74_RS02635 0b60ba29cbfe2bbf038515fc55ac0988 307 Gene3D G3DSA:1.10.10.10 15 94 1.4E-21 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS13075 24ac87527a0b5c9eef4a47528cd2e5b9 325 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 1 322 2.2E-78 T 11-11-2016 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 AUP74_RS13075 24ac87527a0b5c9eef4a47528cd2e5b9 325 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 325 115.093 T 11-11-2016 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 AUP74_RS13075 24ac87527a0b5c9eef4a47528cd2e5b9 325 PIRSF PIRSF002465 1 325 8.4E-99 T 11-11-2016 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 AUP74_RS13075 24ac87527a0b5c9eef4a47528cd2e5b9 325 Gene3D G3DSA:3.40.718.10 1 323 3.2E-105 T 11-11-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AUP74_RS13075 24ac87527a0b5c9eef4a47528cd2e5b9 325 Pfam PF02504 Fatty acid synthesis protein 1 316 3.0E-84 T 11-11-2016 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 AUP74_RS13075 24ac87527a0b5c9eef4a47528cd2e5b9 325 SUPERFAMILY SSF53659 1 323 5.35E-87 T 11-11-2016 AUP74_RS11260 cff8ba3d80ac0732bbad84e6a250660e 568 SUPERFAMILY SSF47226 20 134 2.77E-10 T 11-11-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 AUP74_RS11260 cff8ba3d80ac0732bbad84e6a250660e 568 Gene3D G3DSA:1.20.120.160 25 140 1.8E-9 T 11-11-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 AUP74_RS05440 e1d76699c2cc72cbb72abec504eaa92e 292 Gene3D G3DSA:1.10.443.10 106 281 1.2E-53 T 11-11-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 AUP74_RS05440 e1d76699c2cc72cbb72abec504eaa92e 292 Gene3D G3DSA:1.10.150.130 1 94 3.8E-27 T 11-11-2016 IPR023109 Integrase/recombinase, N-terminal AUP74_RS05440 e1d76699c2cc72cbb72abec504eaa92e 292 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 2 288 2.4E-109 T 11-11-2016 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 AUP74_RS05440 e1d76699c2cc72cbb72abec504eaa92e 292 Pfam PF00589 Phage integrase family 106 273 1.3E-45 T 11-11-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AUP74_RS05440 e1d76699c2cc72cbb72abec504eaa92e 292 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 1 287 58.029 T 11-11-2016 IPR023009 Tyrosine recombinase XerC/XerD AUP74_RS05440 e1d76699c2cc72cbb72abec504eaa92e 292 SUPERFAMILY SSF56349 2 281 1.53E-55 T 11-11-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AUP74_RS05440 e1d76699c2cc72cbb72abec504eaa92e 292 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 1 84 3.1E-20 T 11-11-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 AUP74_RS04010 24ac8b6405a9b85acbc392583ccf65c7 300 Hamap MF_00082_B Acetylglutamate kinase [argB]. 26 297 36.619 T 11-11-2016 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AUP74_RS04010 24ac8b6405a9b85acbc392583ccf65c7 300 Pfam PF00696 Amino acid kinase family 28 274 7.2E-45 T 11-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase AUP74_RS04010 24ac8b6405a9b85acbc392583ccf65c7 300 PRINTS PR00474 Glutamate 5-kinase family signature 247 267 4.7E-8 T 11-11-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 AUP74_RS04010 24ac8b6405a9b85acbc392583ccf65c7 300 PRINTS PR00474 Glutamate 5-kinase family signature 59 73 4.7E-8 T 11-11-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 AUP74_RS04010 24ac8b6405a9b85acbc392583ccf65c7 300 PRINTS PR00474 Glutamate 5-kinase family signature 197 224 4.7E-8 T 11-11-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 AUP74_RS04010 24ac8b6405a9b85acbc392583ccf65c7 300 TIGRFAM TIGR00761 argB: acetylglutamate kinase 29 272 3.2E-74 T 11-11-2016 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AUP74_RS04010 24ac8b6405a9b85acbc392583ccf65c7 300 SUPERFAMILY SSF53633 7 298 1.7E-93 T 11-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase AUP74_RS04010 24ac8b6405a9b85acbc392583ccf65c7 300 Gene3D G3DSA:3.40.1160.10 27 296 1.1E-101 T 11-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase AUP74_RS04010 24ac8b6405a9b85acbc392583ccf65c7 300 PIRSF PIRSF000728 13 297 2.5E-105 T 11-11-2016 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AUP74_RS05170 f79d696009c021da673466c2411bad5e 331 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 255 268 - T 11-11-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 AUP74_RS05170 f79d696009c021da673466c2411bad5e 331 Gene3D G3DSA:3.40.1190.20 1 326 1.9E-83 T 11-11-2016 IPR029056 Ribokinase-like AUP74_RS05170 f79d696009c021da673466c2411bad5e 331 SUPERFAMILY SSF53613 1 324 1.71E-74 T 11-11-2016 IPR029056 Ribokinase-like AUP74_RS05170 f79d696009c021da673466c2411bad5e 331 Pfam PF00294 pfkB family carbohydrate kinase 1 315 1.6E-60 T 11-11-2016 IPR011611 Carbohydrate kinase PfkB AUP74_RS03995 9babc775f8b16aeab8ce472581588e21 224 SUPERFAMILY SSF47781 17 90 1.11E-11 T 11-11-2016 IPR010994 RuvA domain 2-like AUP74_RS03995 9babc775f8b16aeab8ce472581588e21 224 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 173 178 - T 11-11-2016 IPR020891 Uncharacterised protein family UPF0758, conserved site AUP74_RS03995 9babc775f8b16aeab8ce472581588e21 224 TIGRFAM TIGR00608 radc: DNA repair protein RadC 11 224 6.0E-77 T 11-11-2016 IPR001405 RadC protein AUP74_RS03995 9babc775f8b16aeab8ce472581588e21 224 Pfam PF04002 RadC-like JAB domain 105 223 3.0E-45 T 11-11-2016 IPR025657 RadC-like JAB domain AUP74_RS03995 9babc775f8b16aeab8ce472581588e21 224 Gene3D G3DSA:3.40.140.10 101 224 4.7E-50 T 11-11-2016 AUP74_RS03995 9babc775f8b16aeab8ce472581588e21 224 SUPERFAMILY SSF102712 111 192 2.62E-5 T 11-11-2016 AUP74_RS02700 0ed18257841f3fdac35a64f181dcd943 309 SUPERFAMILY SSF52266 27 44 1.17E-8 T 11-11-2016 IPR013830 SGNH hydrolase-type esterase domain AUP74_RS02700 0ed18257841f3fdac35a64f181dcd943 309 SUPERFAMILY SSF52266 93 191 1.17E-8 T 11-11-2016 IPR013830 SGNH hydrolase-type esterase domain AUP74_RS02700 0ed18257841f3fdac35a64f181dcd943 309 SUPERFAMILY SSF52266 237 303 1.17E-8 T 11-11-2016 IPR013830 SGNH hydrolase-type esterase domain AUP74_RS02700 0ed18257841f3fdac35a64f181dcd943 309 Gene3D G3DSA:3.40.50.1110 30 190 5.1E-7 T 11-11-2016 IPR013830 SGNH hydrolase-type esterase domain AUP74_RS02700 0ed18257841f3fdac35a64f181dcd943 309 Gene3D G3DSA:3.40.50.1110 233 303 5.1E-7 T 11-11-2016 IPR013830 SGNH hydrolase-type esterase domain AUP74_RS02700 0ed18257841f3fdac35a64f181dcd943 309 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 30 295 1.5E-7 T 11-11-2016 IPR013830 SGNH hydrolase-type esterase domain AUP74_RS02390 d3a5b13c02baf428c591d2d21b2f9c64 167 Hamap MF_00298 RNA pyrophosphohydrolase [rppH]. 1 156 34.4 T 11-11-2016 IPR022927 RNA pyrophosphohydrolase RppH AUP74_RS02390 d3a5b13c02baf428c591d2d21b2f9c64 167 Pfam PF00293 NUDIX domain 6 146 2.5E-25 T 11-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 AUP74_RS02390 d3a5b13c02baf428c591d2d21b2f9c64 167 PRINTS PR00502 NUDIX hydrolase family signature 33 47 1.9E-7 T 11-11-2016 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AUP74_RS02390 d3a5b13c02baf428c591d2d21b2f9c64 167 PRINTS PR00502 NUDIX hydrolase family signature 47 62 1.9E-7 T 11-11-2016 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AUP74_RS02390 d3a5b13c02baf428c591d2d21b2f9c64 167 SUPERFAMILY SSF55811 5 153 5.55E-29 T 11-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 AUP74_RS02390 d3a5b13c02baf428c591d2d21b2f9c64 167 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 11-11-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AUP74_RS02390 d3a5b13c02baf428c591d2d21b2f9c64 167 Gene3D G3DSA:3.90.79.10 5 152 5.0E-30 T 11-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 AUP74_RS10110 44f5094ae0a8be429033be1e680732b4 257 Pfam PF01551 Peptidase family M23 156 249 3.0E-29 T 11-11-2016 IPR016047 Peptidase M23 AUP74_RS10110 44f5094ae0a8be429033be1e680732b4 257 Gene3D G3DSA:2.70.70.10 117 254 5.6E-39 T 11-11-2016 AUP74_RS10110 44f5094ae0a8be429033be1e680732b4 257 Pfam PF01476 LysM domain 38 79 2.5E-10 T 11-11-2016 IPR018392 LysM domain AUP74_RS10110 44f5094ae0a8be429033be1e680732b4 257 SUPERFAMILY SSF51261 38 253 8.37E-48 T 11-11-2016 IPR011055 Duplicated hybrid motif AUP74_RS10110 44f5094ae0a8be429033be1e680732b4 257 SMART SM00257 37 81 5.7E-8 T 11-11-2016 IPR018392 LysM domain AUP74_RS10110 44f5094ae0a8be429033be1e680732b4 257 Gene3D G3DSA:3.10.350.10 37 80 3.6E-14 T 11-11-2016 IPR018392 LysM domain AUP74_RS04345 25b74ac21058d62d94e4fbc419ff3c27 331 Gene3D G3DSA:3.40.50.920 199 321 1.5E-44 T 11-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 AUP74_RS04345 25b74ac21058d62d94e4fbc419ff3c27 331 SMART SM00861 4 179 4.5E-68 T 11-11-2016 IPR005475 Transketolase-like, pyrimidine-binding domain AUP74_RS04345 25b74ac21058d62d94e4fbc419ff3c27 331 Gene3D G3DSA:3.40.50.970 2 195 2.4E-80 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS04345 25b74ac21058d62d94e4fbc419ff3c27 331 Pfam PF02780 Transketolase, C-terminal domain 198 315 1.8E-38 T 11-11-2016 IPR033248 Transketolase, C-terminal domain AUP74_RS04345 25b74ac21058d62d94e4fbc419ff3c27 331 Pfam PF02779 Transketolase, pyrimidine binding domain 3 178 6.5E-50 T 11-11-2016 IPR005475 Transketolase-like, pyrimidine-binding domain AUP74_RS04345 25b74ac21058d62d94e4fbc419ff3c27 331 SUPERFAMILY SSF52518 4 192 1.02E-68 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS04345 25b74ac21058d62d94e4fbc419ff3c27 331 SUPERFAMILY SSF52922 190 324 8.77E-41 T 11-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 AUP74_RS07210 9df980c11d9d8e30d0a8e64329be4067 162 Pfam PF13511 Domain of unknown function (DUF4124) 14 56 2.5E-12 T 11-11-2016 IPR025392 Domain of unknown function DUF4124 AUP74_RS09910 16ad360b55af823038d746cb7ce295c6 484 SUPERFAMILY SSF51905 21 322 4.86E-66 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS09910 16ad360b55af823038d746cb7ce295c6 484 SUPERFAMILY SSF51905 424 463 4.86E-66 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS09910 16ad360b55af823038d746cb7ce295c6 484 Pfam PF01593 Flavin containing amine oxidoreductase 29 460 2.0E-70 T 11-11-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 AUP74_RS09910 16ad360b55af823038d746cb7ce295c6 484 Gene3D G3DSA:1.10.405.10 121 211 1.6E-31 T 11-11-2016 AUP74_RS09910 16ad360b55af823038d746cb7ce295c6 484 PRINTS PR00757 Flavin-containing amine oxidase signature 307 326 1.2E-34 T 11-11-2016 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 AUP74_RS09910 16ad360b55af823038d746cb7ce295c6 484 PRINTS PR00757 Flavin-containing amine oxidase signature 411 433 1.2E-34 T 11-11-2016 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 AUP74_RS09910 16ad360b55af823038d746cb7ce295c6 484 PRINTS PR00757 Flavin-containing amine oxidase signature 210 232 1.2E-34 T 11-11-2016 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 AUP74_RS09910 16ad360b55af823038d746cb7ce295c6 484 PRINTS PR00757 Flavin-containing amine oxidase signature 390 409 1.2E-34 T 11-11-2016 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 AUP74_RS09910 16ad360b55af823038d746cb7ce295c6 484 PRINTS PR00757 Flavin-containing amine oxidase signature 442 459 1.2E-34 T 11-11-2016 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 AUP74_RS09910 16ad360b55af823038d746cb7ce295c6 484 PRINTS PR00757 Flavin-containing amine oxidase signature 21 40 1.2E-34 T 11-11-2016 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 AUP74_RS09910 16ad360b55af823038d746cb7ce295c6 484 PRINTS PR00757 Flavin-containing amine oxidase signature 187 208 1.2E-34 T 11-11-2016 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 AUP74_RS09910 16ad360b55af823038d746cb7ce295c6 484 Gene3D G3DSA:3.90.660.10 239 411 1.1E-54 T 11-11-2016 AUP74_RS09910 16ad360b55af823038d746cb7ce295c6 484 Gene3D G3DSA:3.50.50.60 21 90 1.3E-7 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS09910 16ad360b55af823038d746cb7ce295c6 484 SUPERFAMILY SSF54373 304 410 5.36E-33 T 11-11-2016 AUP74_RS00350 109ad69f574e20fbe95e004d5318a7d7 106 Pfam PF08850 Domain of unknown function (DUF1820) 1 94 4.4E-45 T 11-11-2016 IPR014949 Protein of unknown function DUF1820 AUP74_RS00350 109ad69f574e20fbe95e004d5318a7d7 106 PIRSF PIRSF028538 1 101 5.3E-46 T 11-11-2016 IPR014949 Protein of unknown function DUF1820 AUP74_RS12445 ea439c16d2d27cd815bb0566cfae5588 494 Pfam PF00361 Proton-conducting membrane transporter 130 423 9.8E-66 T 11-11-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS12445 ea439c16d2d27cd815bb0566cfae5588 494 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 218 239 2.6E-7 T 11-11-2016 AUP74_RS12445 ea439c16d2d27cd815bb0566cfae5588 494 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 418 437 2.6E-7 T 11-11-2016 AUP74_RS12445 ea439c16d2d27cd815bb0566cfae5588 494 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 314 326 2.6E-7 T 11-11-2016 AUP74_RS10420 a63261cbff3d8c4f47153db4607363bf 78 Hamap MF_00404 Probable oxaloacetate decarboxylase gamma chain [oadG]. 1 78 21.128 T 11-11-2016 IPR023424 Oxaloacetate decarboxylase gamma chain, probable GO:0008948 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 AUP74_RS10420 a63261cbff3d8c4f47153db4607363bf 78 TIGRFAM TIGR01195 oadG_fam: sodium pump decarboxylases, gamma subunit 5 76 7.0E-12 T 11-11-2016 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0071436 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 AUP74_RS10420 a63261cbff3d8c4f47153db4607363bf 78 Pfam PF04277 Oxaloacetate decarboxylase, gamma chain 7 74 4.0E-12 T 11-11-2016 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0071436 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 AUP74_RS14030 fdebfd564318a1a1e5e0eedd37695490 357 Gene3D G3DSA:3.20.20.10 11 212 2.5E-59 T 11-11-2016 IPR029066 PLP-binding barrel AUP74_RS14030 fdebfd564318a1a1e5e0eedd37695490 357 Pfam PF00842 Alanine racemase, C-terminal domain 232 354 5.3E-35 T 11-11-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AUP74_RS14030 fdebfd564318a1a1e5e0eedd37695490 357 Gene3D G3DSA:2.40.37.10 213 355 5.2E-48 T 11-11-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AUP74_RS14030 fdebfd564318a1a1e5e0eedd37695490 357 SUPERFAMILY SSF51419 9 221 6.02E-58 T 11-11-2016 IPR029066 PLP-binding barrel AUP74_RS14030 fdebfd564318a1a1e5e0eedd37695490 357 SMART SM01005 231 355 1.3E-59 T 11-11-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AUP74_RS14030 fdebfd564318a1a1e5e0eedd37695490 357 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 31 41 - T 11-11-2016 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AUP74_RS14030 fdebfd564318a1a1e5e0eedd37695490 357 TIGRFAM TIGR00492 alr: alanine racemase 5 354 4.5E-94 T 11-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AUP74_RS14030 fdebfd564318a1a1e5e0eedd37695490 357 SUPERFAMILY SSF50621 225 356 3.45E-42 T 11-11-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AUP74_RS14030 fdebfd564318a1a1e5e0eedd37695490 357 PRINTS PR00992 Alanine racemase signature 154 165 1.3E-59 T 11-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AUP74_RS14030 fdebfd564318a1a1e5e0eedd37695490 357 PRINTS PR00992 Alanine racemase signature 337 350 1.3E-59 T 11-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AUP74_RS14030 fdebfd564318a1a1e5e0eedd37695490 357 PRINTS PR00992 Alanine racemase signature 120 132 1.3E-59 T 11-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AUP74_RS14030 fdebfd564318a1a1e5e0eedd37695490 357 PRINTS PR00992 Alanine racemase signature 247 262 1.3E-59 T 11-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AUP74_RS14030 fdebfd564318a1a1e5e0eedd37695490 357 PRINTS PR00992 Alanine racemase signature 26 42 1.3E-59 T 11-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AUP74_RS14030 fdebfd564318a1a1e5e0eedd37695490 357 PRINTS PR00992 Alanine racemase signature 285 302 1.3E-59 T 11-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AUP74_RS14030 fdebfd564318a1a1e5e0eedd37695490 357 PRINTS PR00992 Alanine racemase signature 191 218 1.3E-59 T 11-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AUP74_RS14030 fdebfd564318a1a1e5e0eedd37695490 357 PRINTS PR00992 Alanine racemase signature 60 78 1.3E-59 T 11-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AUP74_RS14030 fdebfd564318a1a1e5e0eedd37695490 357 PRINTS PR00992 Alanine racemase signature 264 279 1.3E-59 T 11-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AUP74_RS14030 fdebfd564318a1a1e5e0eedd37695490 357 Hamap MF_01201 Alanine racemase. 2 355 32.092 T 11-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AUP74_RS14030 fdebfd564318a1a1e5e0eedd37695490 357 Pfam PF01168 Alanine racemase, N-terminal domain 9 218 5.5E-58 T 11-11-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AUP74_RS12115 40e5c7098d87e88f071d376269c2a6f8 195 Pfam PF01545 Cation efflux family 12 185 1.4E-16 T 11-11-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AUP74_RS12115 40e5c7098d87e88f071d376269c2a6f8 195 Gene3D G3DSA:1.20.1510.10 8 185 1.6E-25 T 11-11-2016 IPR027469 Cation efflux protein transmembrane domain AUP74_RS12115 40e5c7098d87e88f071d376269c2a6f8 195 SUPERFAMILY SSF161111 5 186 2.62E-34 T 11-11-2016 AUP74_RS12555 e91b6ea47bb1f651e554421b7f547dba 440 ProSitePatterns PS01276 Peptidase family U32 signature. 162 180 - T 11-11-2016 IPR001539 Peptidase U32 GO:0006508|GO:0008233 AUP74_RS12555 e91b6ea47bb1f651e554421b7f547dba 440 Pfam PF16325 Peptidase family U32 C-terminal domain 354 420 6.0E-16 T 11-11-2016 IPR032525 Peptidase family U32, C-terminal AUP74_RS12555 e91b6ea47bb1f651e554421b7f547dba 440 Pfam PF01136 Peptidase family U32 79 336 4.2E-98 T 11-11-2016 IPR001539 Peptidase U32 GO:0006508|GO:0008233 AUP74_RS11915 d5bab2d887d16d308682379db0f8185c 446 TIGRFAM TIGR01936 nqrA: NADH:ubiquinone oxidoreductase, Na(+)-translocating, A subunit 3 446 2.0E-182 T 11-11-2016 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 AUP74_RS11915 d5bab2d887d16d308682379db0f8185c 446 Hamap MF_00425 Na(+)-translocating NADH-quinone reductase subunit A [nqrA]. 1 446 46.53 T 11-11-2016 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 AUP74_RS11915 d5bab2d887d16d308682379db0f8185c 446 Pfam PF05896 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) 3 256 4.4E-110 T 11-11-2016 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 AUP74_RS11915 d5bab2d887d16d308682379db0f8185c 446 Pfam PF11973 NQRA C-terminal domain 261 310 3.3E-19 T 11-11-2016 IPR022615 Na(+)-translocating NADH-quinone reductase subunit A, C-terminal domain GO:0016655|GO:0055114 AUP74_RS12625 609076d866b880d82c0e9f6da12bce77 268 Gene3D G3DSA:3.40.50.700 2 166 9.1E-26 T 11-11-2016 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS12625 609076d866b880d82c0e9f6da12bce77 268 SUPERFAMILY SSF56770 3 215 9.03E-44 T 11-11-2016 AUP74_RS12625 609076d866b880d82c0e9f6da12bce77 268 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 14 150 9.2E-25 T 11-11-2016 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS01955 2f0292de9856ba55a3fcbcf38eb3b2b9 909 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 870 882 2.4E-8 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS01955 2f0292de9856ba55a3fcbcf38eb3b2b9 909 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 840 854 2.4E-8 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS01955 2f0292de9856ba55a3fcbcf38eb3b2b9 909 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 854 870 2.4E-8 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS01955 2f0292de9856ba55a3fcbcf38eb3b2b9 909 SUPERFAMILY SSF52540 21 268 2.4E-10 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS01955 2f0292de9856ba55a3fcbcf38eb3b2b9 909 SUPERFAMILY SSF46894 833 896 1.46E-16 T 11-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AUP74_RS01955 2f0292de9856ba55a3fcbcf38eb3b2b9 909 Pfam PF00196 Bacterial regulatory proteins, luxR family 839 894 4.2E-17 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS01955 2f0292de9856ba55a3fcbcf38eb3b2b9 909 Pfam PF13401 AAA domain 31 142 2.1E-6 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS01955 2f0292de9856ba55a3fcbcf38eb3b2b9 909 Gene3D G3DSA:3.40.50.300 30 177 1.7E-4 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS01955 2f0292de9856ba55a3fcbcf38eb3b2b9 909 SMART SM00421 837 894 2.9E-18 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS01955 2f0292de9856ba55a3fcbcf38eb3b2b9 909 ProSitePatterns PS00622 LuxR-type HTH domain signature. 854 881 - T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS01955 2f0292de9856ba55a3fcbcf38eb3b2b9 909 Gene3D G3DSA:1.10.10.10 837 896 1.5E-20 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS01955 2f0292de9856ba55a3fcbcf38eb3b2b9 909 Gene3D G3DSA:1.25.40.10 441 807 1.7E-54 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS01955 2f0292de9856ba55a3fcbcf38eb3b2b9 909 SUPERFAMILY SSF48452 442 803 9.01E-91 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS09255 4669543b2fec3a0828236ed828859a5f 175 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 18 158 8.0E-31 T 11-11-2016 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS01935 8038503d854ca43f0ea57d0c587d7c28 141 Pfam PF03061 Thioesterase superfamily 51 127 4.4E-18 T 11-11-2016 IPR006683 Thioesterase domain Reactome: R-HSA-75105 AUP74_RS01935 8038503d854ca43f0ea57d0c587d7c28 141 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 23 136 2.0E-37 T 11-11-2016 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 AUP74_RS01935 8038503d854ca43f0ea57d0c587d7c28 141 Gene3D G3DSA:3.10.129.10 2 140 1.1E-47 T 11-11-2016 IPR029069 HotDog domain AUP74_RS01935 8038503d854ca43f0ea57d0c587d7c28 141 SUPERFAMILY SSF54637 23 140 2.87E-32 T 11-11-2016 IPR029069 HotDog domain AUP74_RS15055 044b1d5aabc9ba33c94e8a5f4e935104 226 Pfam PF04298 Putative neutral zinc metallopeptidase 8 224 2.9E-50 T 11-11-2016 IPR007395 Putative neutral zinc metallopeptidase AUP74_RS06745 51d07f81f0802231e1b58184908592fa 397 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 397 1.4E-226 T 11-11-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AUP74_RS06745 51d07f81f0802231e1b58184908592fa 397 SUPERFAMILY SSF50447 208 304 1.81E-29 T 11-11-2016 IPR009000 Translation protein, beta-barrel domain AUP74_RS06745 51d07f81f0802231e1b58184908592fa 397 SUPERFAMILY SSF52540 6 222 3.8E-61 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS06745 51d07f81f0802231e1b58184908592fa 397 PRINTS PR00315 GTP-binding elongation factor signature 94 105 2.1E-24 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AUP74_RS06745 51d07f81f0802231e1b58184908592fa 397 PRINTS PR00315 GTP-binding elongation factor signature 131 140 2.1E-24 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AUP74_RS06745 51d07f81f0802231e1b58184908592fa 397 PRINTS PR00315 GTP-binding elongation factor signature 78 88 2.1E-24 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AUP74_RS06745 51d07f81f0802231e1b58184908592fa 397 PRINTS PR00315 GTP-binding elongation factor signature 58 66 2.1E-24 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AUP74_RS06745 51d07f81f0802231e1b58184908592fa 397 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.1E-24 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AUP74_RS06745 51d07f81f0802231e1b58184908592fa 397 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 11-11-2016 IPR031157 Tr-type G domain, conserved site AUP74_RS06745 51d07f81f0802231e1b58184908592fa 397 Gene3D G3DSA:2.40.30.10 212 301 1.8E-35 T 11-11-2016 AUP74_RS06745 51d07f81f0802231e1b58184908592fa 397 Gene3D G3DSA:2.40.30.10 303 396 5.5E-48 T 11-11-2016 AUP74_RS06745 51d07f81f0802231e1b58184908592fa 397 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 397 59.685 T 11-11-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AUP74_RS06745 51d07f81f0802231e1b58184908592fa 397 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 148 9.6E-15 T 11-11-2016 IPR005225 Small GTP-binding protein domain GO:0005525 AUP74_RS06745 51d07f81f0802231e1b58184908592fa 397 SUPERFAMILY SSF50465 305 397 5.47E-36 T 11-11-2016 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal AUP74_RS06745 51d07f81f0802231e1b58184908592fa 397 Pfam PF03143 Elongation factor Tu C-terminal domain 301 395 7.5E-34 T 11-11-2016 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal AUP74_RS06745 51d07f81f0802231e1b58184908592fa 397 Pfam PF00009 Elongation factor Tu GTP binding domain 10 204 2.1E-58 T 11-11-2016 AUP74_RS06745 51d07f81f0802231e1b58184908592fa 397 Pfam PF03144 Elongation factor Tu domain 2 228 296 6.3E-17 T 11-11-2016 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AUP74_RS06745 51d07f81f0802231e1b58184908592fa 397 Gene3D G3DSA:3.40.50.300 3 211 1.1E-67 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS02830 acf015a2f4df8926c30301c9ff513ed0 128 Gene3D G3DSA:3.40.50.10600 1 125 1.2E-42 T 11-11-2016 IPR021866 SpoIIAA-like AUP74_RS02830 acf015a2f4df8926c30301c9ff513ed0 128 Pfam PF11964 SpoIIAA-like 21 124 6.3E-19 T 11-11-2016 IPR021866 SpoIIAA-like AUP74_RS02830 acf015a2f4df8926c30301c9ff513ed0 128 SUPERFAMILY SSF52091 1 124 2.28E-39 T 11-11-2016 IPR002645 STAS domain AUP74_RS01900 c57ca7b0d7c8b1ba76ceeba0c1fdb486 649 Pfam PF03600 Citrate transporter 16 203 2.5E-27 T 11-11-2016 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 AUP74_RS01900 c57ca7b0d7c8b1ba76ceeba0c1fdb486 649 Gene3D G3DSA:3.30.70.1450 366 448 5.6E-19 T 11-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AUP74_RS01900 c57ca7b0d7c8b1ba76ceeba0c1fdb486 649 Gene3D G3DSA:3.30.70.1450 214 297 1.3E-11 T 11-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AUP74_RS01900 c57ca7b0d7c8b1ba76ceeba0c1fdb486 649 Pfam PF02080 TrkA-C domain 369 435 2.2E-10 T 11-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AUP74_RS01900 c57ca7b0d7c8b1ba76ceeba0c1fdb486 649 Pfam PF02080 TrkA-C domain 218 286 2.2E-6 T 11-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AUP74_RS01900 c57ca7b0d7c8b1ba76ceeba0c1fdb486 649 SUPERFAMILY SSF116726 210 292 1.01E-12 T 11-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AUP74_RS01900 c57ca7b0d7c8b1ba76ceeba0c1fdb486 649 SUPERFAMILY SSF116726 362 445 2.22E-16 T 11-11-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AUP74_RS01900 c57ca7b0d7c8b1ba76ceeba0c1fdb486 649 Pfam PF00939 Sodium:sulfate symporter transmembrane region 453 648 8.0E-16 T 11-11-2016 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 AUP74_RS03065 7c00b9937e8ccc7f6a4f29e67293e2c1 194 SUPERFAMILY SSF50475 9 179 6.07E-37 T 11-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 AUP74_RS03065 7c00b9937e8ccc7f6a4f29e67293e2c1 194 Gene3D G3DSA:2.30.110.10 1 191 6.2E-63 T 11-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 AUP74_RS03065 7c00b9937e8ccc7f6a4f29e67293e2c1 194 Pfam PF04299 Putative FMN-binding domain 1 153 1.2E-46 T 11-11-2016 IPR007396 Transcriptional regulator PAI 2-type AUP74_RS03065 7c00b9937e8ccc7f6a4f29e67293e2c1 194 PIRSF PIRSF010372 1 194 5.0E-58 T 11-11-2016 IPR007396 Transcriptional regulator PAI 2-type AUP74_RS16070 95025f470384e6b674a42ca0b0fceb0b 284 Pfam PF01039 Carboxyl transferase domain 102 240 5.1E-13 T 11-11-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AUP74_RS16070 95025f470384e6b674a42ca0b0fceb0b 284 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 283 36.586 T 11-11-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 AUP74_RS16070 95025f470384e6b674a42ca0b0fceb0b 284 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 1 283 3.2E-122 T 11-11-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 AUP74_RS16070 95025f470384e6b674a42ca0b0fceb0b 284 Gene3D G3DSA:3.90.226.10 21 283 1.1E-70 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS16070 95025f470384e6b674a42ca0b0fceb0b 284 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 202 219 8.3E-34 T 11-11-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 AUP74_RS16070 95025f470384e6b674a42ca0b0fceb0b 284 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 165 183 8.3E-34 T 11-11-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 AUP74_RS16070 95025f470384e6b674a42ca0b0fceb0b 284 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 231 242 8.3E-34 T 11-11-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 AUP74_RS16070 95025f470384e6b674a42ca0b0fceb0b 284 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 131 145 8.3E-34 T 11-11-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 AUP74_RS16070 95025f470384e6b674a42ca0b0fceb0b 284 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 253 262 8.3E-34 T 11-11-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 AUP74_RS16070 95025f470384e6b674a42ca0b0fceb0b 284 SUPERFAMILY SSF52096 27 283 8.39E-83 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS15555 90c68f9ffd64045762433b2558ab8124 255 Gene3D G3DSA:1.10.1270.20 167 249 4.2E-36 T 11-11-2016 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 AUP74_RS15555 90c68f9ffd64045762433b2558ab8124 255 Gene3D G3DSA:3.40.1280.10 5 166 4.4E-64 T 11-11-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AUP74_RS15555 90c68f9ffd64045762433b2558ab8124 255 PIRSF PIRSF000386 4 255 7.4E-98 T 11-11-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 AUP74_RS15555 90c68f9ffd64045762433b2558ab8124 255 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 5 239 2.2E-95 T 11-11-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 AUP74_RS15555 90c68f9ffd64045762433b2558ab8124 255 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 255 112.943 T 11-11-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 AUP74_RS15555 90c68f9ffd64045762433b2558ab8124 255 SUPERFAMILY SSF75217 5 251 3.14E-99 T 11-11-2016 IPR029028 Alpha/beta knot methyltransferases AUP74_RS15555 90c68f9ffd64045762433b2558ab8124 255 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 26 227 2.3E-63 T 11-11-2016 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 AUP74_RS07110 284434a576ca3c0bd271bc06f1bb1f73 360 Pfam PF16074 Type IV Pilus-assembly protein W 243 356 1.8E-17 T 11-11-2016 IPR032092 Type IV Pilus-assembly protein W GO:0043683 AUP74_RS07110 284434a576ca3c0bd271bc06f1bb1f73 360 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 8 28 - T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS07110 284434a576ca3c0bd271bc06f1bb1f73 360 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 6 29 2.6E-6 T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS07110 284434a576ca3c0bd271bc06f1bb1f73 360 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 7 26 1.7E-4 T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS03345 7583c4b76b4a9ce8548f08effc42d5b7 1231 Gene3D G3DSA:3.40.50.300 31 114 4.6E-18 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03345 7583c4b76b4a9ce8548f08effc42d5b7 1231 Gene3D G3DSA:3.40.50.300 161 251 4.6E-18 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03345 7583c4b76b4a9ce8548f08effc42d5b7 1231 SUPERFAMILY SSF52540 16 163 2.28E-26 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03345 7583c4b76b4a9ce8548f08effc42d5b7 1231 SUPERFAMILY SSF52540 190 258 2.28E-26 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03345 7583c4b76b4a9ce8548f08effc42d5b7 1231 SMART SM00490 727 818 1.4E-4 T 11-11-2016 IPR001650 Helicase, C-terminal AUP74_RS03345 7583c4b76b4a9ce8548f08effc42d5b7 1231 Gene3D G3DSA:3.40.50.300 746 816 1.7E-9 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03345 7583c4b76b4a9ce8548f08effc42d5b7 1231 Gene3D G3DSA:3.40.50.300 405 450 1.7E-9 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03345 7583c4b76b4a9ce8548f08effc42d5b7 1231 SMART SM00487 33 279 1.2E-6 T 11-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain AUP74_RS03345 7583c4b76b4a9ce8548f08effc42d5b7 1231 Pfam PF04851 Type III restriction enzyme, res subunit 41 245 7.3E-15 T 11-11-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 AUP74_RS03345 7583c4b76b4a9ce8548f08effc42d5b7 1231 SUPERFAMILY SSF52540 736 876 1.77E-16 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03345 7583c4b76b4a9ce8548f08effc42d5b7 1231 SUPERFAMILY SSF52540 59 110 1.77E-16 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS03345 7583c4b76b4a9ce8548f08effc42d5b7 1231 Pfam PF00271 Helicase conserved C-terminal domain 756 816 1.0E-6 T 11-11-2016 IPR001650 Helicase, C-terminal AUP74_RS08380 fb2c53c2506ca53e5443abcf01f3882d 862 SUPERFAMILY SSF82866 629 844 3.79E-33 T 11-11-2016 AUP74_RS08380 fb2c53c2506ca53e5443abcf01f3882d 862 SUPERFAMILY SSF82866 265 420 8.5E-29 T 11-11-2016 AUP74_RS08380 fb2c53c2506ca53e5443abcf01f3882d 862 Gene3D G3DSA:1.20.1640.10 247 426 3.2E-28 T 11-11-2016 AUP74_RS08380 fb2c53c2506ca53e5443abcf01f3882d 862 Gene3D G3DSA:1.20.1640.10 679 847 8.1E-32 T 11-11-2016 AUP74_RS08380 fb2c53c2506ca53e5443abcf01f3882d 862 Pfam PF03176 MMPL family 646 840 1.1E-13 T 11-11-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 AUP74_RS08380 fb2c53c2506ca53e5443abcf01f3882d 862 Pfam PF03176 MMPL family 217 419 1.4E-13 T 11-11-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 AUP74_RS08380 fb2c53c2506ca53e5443abcf01f3882d 862 PRINTS PR00702 Acriflavin resistance protein family signature 739 763 2.6E-6 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS08380 fb2c53c2506ca53e5443abcf01f3882d 862 PRINTS PR00702 Acriflavin resistance protein family signature 814 837 2.6E-6 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS08380 fb2c53c2506ca53e5443abcf01f3882d 862 PRINTS PR00702 Acriflavin resistance protein family signature 687 710 2.6E-6 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS08380 fb2c53c2506ca53e5443abcf01f3882d 862 PRINTS PR00702 Acriflavin resistance protein family signature 363 387 2.6E-6 T 11-11-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS03720 5b4f056dda3294f735ee33f3fad17455 247 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 154 182 1.1E-46 T 11-11-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AUP74_RS03720 5b4f056dda3294f735ee33f3fad17455 247 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 8 35 1.1E-46 T 11-11-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AUP74_RS03720 5b4f056dda3294f735ee33f3fad17455 247 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 103 129 1.1E-46 T 11-11-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AUP74_RS03720 5b4f056dda3294f735ee33f3fad17455 247 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 85 103 1.1E-46 T 11-11-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AUP74_RS03720 5b4f056dda3294f735ee33f3fad17455 247 Pfam PF00902 Sec-independent protein translocase protein (TatC) 11 221 3.2E-65 T 11-11-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AUP74_RS03720 5b4f056dda3294f735ee33f3fad17455 247 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 2 240 17.725 T 11-11-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AUP74_RS03720 5b4f056dda3294f735ee33f3fad17455 247 ProSitePatterns PS01218 TatC family signature. 154 173 - T 11-11-2016 IPR019820 Sec-independent periplasmic protein translocase, conserved site AUP74_RS03720 5b4f056dda3294f735ee33f3fad17455 247 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 9 226 3.1E-71 T 11-11-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AUP74_RS02535 adac9927b5faf9ddb997d52994add0a1 511 Gene3D G3DSA:1.25.40.80 197 322 2.8E-10 T 11-11-2016 AUP74_RS02535 adac9927b5faf9ddb997d52994add0a1 511 Pfam PF04244 Deoxyribodipyrimidine photo-lyase-related protein 5 225 1.1E-74 T 11-11-2016 IPR007357 Deoxyribodipyrimidine photolyase-related protein AUP74_RS02535 adac9927b5faf9ddb997d52994add0a1 511 SUPERFAMILY SSF48173 230 494 3.14E-57 T 11-11-2016 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 AUP74_RS03575 e1f1236b1ba1420cd41f3a031000530f 220 Pfam PF13511 Domain of unknown function (DUF4124) 30 74 4.0E-7 T 11-11-2016 IPR025392 Domain of unknown function DUF4124 AUP74_RS05035 fba68437e7114f66b089248212e048e8 486 Pfam PF13440 Polysaccharide biosynthesis protein 19 311 3.7E-35 T 11-11-2016 AUP74_RS14065 da0b1c5bf337404398afebdd22500f1c 835 Gene3D G3DSA:2.170.130.10 60 196 5.2E-23 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS14065 da0b1c5bf337404398afebdd22500f1c 835 Gene3D G3DSA:2.40.170.20 217 835 1.6E-56 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS14065 da0b1c5bf337404398afebdd22500f1c 835 Pfam PF07715 TonB-dependent Receptor Plug Domain 78 187 3.0E-9 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS14065 da0b1c5bf337404398afebdd22500f1c 835 SUPERFAMILY SSF56935 278 835 2.38E-83 T 11-11-2016 AUP74_RS14065 da0b1c5bf337404398afebdd22500f1c 835 SUPERFAMILY SSF56935 61 250 2.38E-83 T 11-11-2016 AUP74_RS10315 594a4ca1118d6f74ab726d1caf1b1909 139 Gene3D G3DSA:3.30.70.900 37 129 2.8E-8 T 11-11-2016 AUP74_RS10315 594a4ca1118d6f74ab726d1caf1b1909 139 Pfam PF07045 Domain of unknown function (DUF1330) 38 129 1.7E-7 T 11-11-2016 IPR010753 Domain of unknown function DUF1330 AUP74_RS10315 594a4ca1118d6f74ab726d1caf1b1909 139 SUPERFAMILY SSF54909 37 129 4.93E-6 T 11-11-2016 IPR011008 Dimeric alpha-beta barrel AUP74_RS11755 9f800ee02ebb0db51399f8275d232eef 616 SUPERFAMILY SSF48452 360 451 8.59E-13 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS11755 9f800ee02ebb0db51399f8275d232eef 616 Pfam PF13519 von Willebrand factor type A domain 95 202 3.2E-14 T 11-11-2016 IPR002035 von Willebrand factor, type A AUP74_RS11755 9f800ee02ebb0db51399f8275d232eef 616 SUPERFAMILY SSF53300 95 283 7.6E-19 T 11-11-2016 IPR002035 von Willebrand factor, type A AUP74_RS11755 9f800ee02ebb0db51399f8275d232eef 616 Gene3D G3DSA:1.25.40.10 383 451 4.1E-11 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS11755 9f800ee02ebb0db51399f8275d232eef 616 Pfam PF00515 Tetratricopeptide repeat 406 438 6.6E-10 T 11-11-2016 IPR001440 Tetratricopeptide repeat 1 GO:0005515 AUP74_RS11755 9f800ee02ebb0db51399f8275d232eef 616 SMART SM00028 406 439 5.0E-8 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS11755 9f800ee02ebb0db51399f8275d232eef 616 SMART SM00327 91 291 4.6E-4 T 11-11-2016 IPR002035 von Willebrand factor, type A AUP74_RS13610 a4869624264ff7c6bbee01153571da77 505 SUPERFAMILY SSF53649 3 497 1.09E-111 T 11-11-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 AUP74_RS13610 a4869624264ff7c6bbee01153571da77 505 Gene3D G3DSA:3.40.720.10 5 149 1.9E-95 T 11-11-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 AUP74_RS13610 a4869624264ff7c6bbee01153571da77 505 Gene3D G3DSA:3.40.720.10 184 407 1.9E-95 T 11-11-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 AUP74_RS13610 a4869624264ff7c6bbee01153571da77 505 Pfam PF00884 Sulfatase 6 362 4.5E-63 T 11-11-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 AUP74_RS13610 a4869624264ff7c6bbee01153571da77 505 Gene3D G3DSA:3.30.1120.10 408 483 2.2E-12 T 11-11-2016 AUP74_RS13610 a4869624264ff7c6bbee01153571da77 505 Pfam PF14707 C-terminal region of aryl-sulfatase 393 483 1.2E-12 T 11-11-2016 AUP74_RS08660 1d68f4c96ef6d6c2d7d06fde676610e4 182 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 178 2.0E-71 T 11-11-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 AUP74_RS08660 1d68f4c96ef6d6c2d7d06fde676610e4 182 SUPERFAMILY SSF51182 1 179 8.31E-78 T 11-11-2016 IPR011051 RmlC-like cupin domain AUP74_RS08660 1d68f4c96ef6d6c2d7d06fde676610e4 182 Gene3D G3DSA:2.60.120.10 1 179 7.2E-83 T 11-11-2016 IPR014710 RmlC-like jelly roll fold AUP74_RS08660 1d68f4c96ef6d6c2d7d06fde676610e4 182 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 2 178 6.1E-84 T 11-11-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 AUP74_RS08660 1d68f4c96ef6d6c2d7d06fde676610e4 182 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 177 1.4E-75 T 11-11-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 AUP74_RS16300 f5069fd2dc379cd28ceb299b1c29fba1 194 TIGRFAM TIGR00052 TIGR00052: nudix-type nucleoside diphosphatase, YffH/AdpP family 32 187 1.8E-43 T 11-11-2016 IPR004385 Nucleoside diphosphate pyrophosphatase GO:0016818|GO:0046872 Reactome: R-HSA-480985 AUP74_RS16300 f5069fd2dc379cd28ceb299b1c29fba1 194 Gene3D G3DSA:3.90.79.10 5 187 2.7E-52 T 11-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 AUP74_RS16300 f5069fd2dc379cd28ceb299b1c29fba1 194 SUPERFAMILY SSF55811 10 189 1.9E-43 T 11-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 AUP74_RS16300 f5069fd2dc379cd28ceb299b1c29fba1 194 Pfam PF00293 NUDIX domain 44 178 1.1E-11 T 11-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 AUP74_RS01325 31f365a819fc91825af82c1da04109ef 279 SUPERFAMILY SSF53474 1 276 3.27E-88 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS01325 31f365a819fc91825af82c1da04109ef 279 Pfam PF00756 Putative esterase 21 270 3.5E-67 T 11-11-2016 IPR000801 Putative esterase Reactome: R-HSA-156590 AUP74_RS01325 31f365a819fc91825af82c1da04109ef 279 Gene3D G3DSA:3.40.50.1820 1 276 1.3E-78 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS01325 31f365a819fc91825af82c1da04109ef 279 TIGRFAM TIGR02821 fghA_ester_D: S-formylglutathione hydrolase 2 275 5.1E-123 T 11-11-2016 IPR014186 S-formylglutathione hydrolase GO:0018738|GO:0046294 KEGG: 00680+3.1.2.12|MetaCyc: PWY-1801|Reactome: R-HSA-156590 AUP74_RS12495 d4cd28847c910766098c63660395e1d7 310 SUPERFAMILY SSF46689 199 248 6.44E-11 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS12495 d4cd28847c910766098c63660395e1d7 310 Gene3D G3DSA:1.10.10.60 253 295 1.5E-8 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS12495 d4cd28847c910766098c63660395e1d7 310 SUPERFAMILY SSF46689 251 300 7.17E-8 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS12495 d4cd28847c910766098c63660395e1d7 310 SMART SM00342 215 298 2.9E-19 T 11-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AUP74_RS12495 d4cd28847c910766098c63660395e1d7 310 Pfam PF12833 Helix-turn-helix domain 221 296 2.1E-17 T 11-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AUP74_RS12495 d4cd28847c910766098c63660395e1d7 310 Gene3D G3DSA:1.10.10.60 199 252 7.4E-16 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS12495 d4cd28847c910766098c63660395e1d7 310 Pfam PF06719 AraC-type transcriptional regulator N-terminus 35 185 9.7E-43 T 11-11-2016 IPR009594 Transcription regulator HTH, AraC, N-terminal AUP74_RS04290 0912fd10752b8055c76819e628769daf 200 Gene3D G3DSA:1.20.1050.10 91 187 2.0E-36 T 11-11-2016 IPR010987 Glutathione S-transferase, C-terminal-like AUP74_RS04290 0912fd10752b8055c76819e628769daf 200 Gene3D G3DSA:3.40.30.10 1 90 1.1E-23 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS04290 0912fd10752b8055c76819e628769daf 200 SUPERFAMILY SSF47616 79 195 4.46E-27 T 11-11-2016 IPR010987 Glutathione S-transferase, C-terminal-like AUP74_RS04290 0912fd10752b8055c76819e628769daf 200 SUPERFAMILY SSF52833 1 86 1.43E-16 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS04290 0912fd10752b8055c76819e628769daf 200 Pfam PF13417 Glutathione S-transferase, N-terminal domain 16 80 1.3E-5 T 11-11-2016 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 AUP74_RS04290 0912fd10752b8055c76819e628769daf 200 Pfam PF00043 Glutathione S-transferase, C-terminal domain 104 188 2.5E-14 T 11-11-2016 IPR004046 Glutathione S-transferase, C-terminal AUP74_RS16735 c393cc0b91a598c00abebed66babcd40 365 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 14 362 37.031 T 11-11-2016 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AUP74_RS16735 c393cc0b91a598c00abebed66babcd40 365 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 14 151 3.9E-44 T 11-11-2016 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AUP74_RS16735 c393cc0b91a598c00abebed66babcd40 365 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 12 357 1.7E-105 T 11-11-2016 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AUP74_RS16735 c393cc0b91a598c00abebed66babcd40 365 Gene3D G3DSA:3.40.50.2000 12 201 1.3E-70 T 11-11-2016 AUP74_RS16735 c393cc0b91a598c00abebed66babcd40 365 SUPERFAMILY SSF53756 12 362 3.53E-118 T 11-11-2016 AUP74_RS16735 c393cc0b91a598c00abebed66babcd40 365 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 190 353 5.2E-34 T 11-11-2016 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 AUP74_RS06680 e942b8b1f2448c9fbbe8e9c930bbdb24 300 SUPERFAMILY SSF51430 7 295 7.07E-74 T 11-11-2016 IPR023210 NADP-dependent oxidoreductase domain AUP74_RS06680 e942b8b1f2448c9fbbe8e9c930bbdb24 300 PRINTS PR00069 Aldo-keto reductase signature 144 161 2.8E-9 T 11-11-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AUP74_RS06680 e942b8b1f2448c9fbbe8e9c930bbdb24 300 PRINTS PR00069 Aldo-keto reductase signature 113 131 2.8E-9 T 11-11-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AUP74_RS06680 e942b8b1f2448c9fbbe8e9c930bbdb24 300 Pfam PF00248 Aldo/keto reductase family 17 282 3.5E-56 T 11-11-2016 IPR023210 NADP-dependent oxidoreductase domain AUP74_RS06680 e942b8b1f2448c9fbbe8e9c930bbdb24 300 Gene3D G3DSA:3.20.20.100 6 284 1.6E-67 T 11-11-2016 IPR023210 NADP-dependent oxidoreductase domain AUP74_RS06680 e942b8b1f2448c9fbbe8e9c930bbdb24 300 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 144 161 - T 11-11-2016 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 AUP74_RS14475 564d1f482f10ff363f5ccc62e9a583e8 305 SUPERFAMILY SSF51569 1 284 8.97E-67 T 11-11-2016 AUP74_RS14475 564d1f482f10ff363f5ccc62e9a583e8 305 Pfam PF00682 HMGL-like 5 278 1.2E-49 T 11-11-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 AUP74_RS14475 564d1f482f10ff363f5ccc62e9a583e8 305 Gene3D G3DSA:3.20.20.70 3 282 1.1E-70 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS10610 1b4ef78aafd0cf75f6b80109171199af 445 SUPERFAMILY SSF52151 50 228 2.33E-22 T 11-11-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 AUP74_RS10610 1b4ef78aafd0cf75f6b80109171199af 445 SUPERFAMILY SSF52151 269 297 2.33E-22 T 11-11-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 AUP74_RS10610 1b4ef78aafd0cf75f6b80109171199af 445 Gene3D G3DSA:3.40.1090.10 48 118 5.7E-10 T 11-11-2016 AUP74_RS10610 1b4ef78aafd0cf75f6b80109171199af 445 Pfam PF01734 Patatin-like phospholipase 52 289 2.6E-19 T 11-11-2016 IPR002641 Patatin/Phospholipase A2-related GO:0006629 AUP74_RS11105 a0ed02db110bb266d6511ba1aaf5d87d 119 SUPERFAMILY SSF46458 3 110 2.16E-6 T 11-11-2016 IPR009050 Globin-like AUP74_RS11105 a0ed02db110bb266d6511ba1aaf5d87d 119 Gene3D G3DSA:1.10.490.10 2 106 1.1E-4 T 11-11-2016 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 AUP74_RS15890 3d38a39f60818aa86311863331533267 363 Pfam PF04055 Radical SAM superfamily 75 252 4.9E-13 T 11-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 AUP74_RS15890 3d38a39f60818aa86311863331533267 363 SMART SM00729 71 296 8.1E-4 T 11-11-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 AUP74_RS15890 3d38a39f60818aa86311863331533267 363 SUPERFAMILY SSF102114 56 289 3.01E-14 T 11-11-2016 AUP74_RS15890 3d38a39f60818aa86311863331533267 363 Gene3D G3DSA:3.20.20.70 76 262 4.5E-7 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS07545 dca0491e6efc9f080720e96fbae472cc 260 SUPERFAMILY SSF140959 4 259 1.31E-86 T 11-11-2016 AUP74_RS07545 dca0491e6efc9f080720e96fbae472cc 260 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 1 260 37.519 T 11-11-2016 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 AUP74_RS07545 dca0491e6efc9f080720e96fbae472cc 260 Pfam PF03301 Tryptophan 2,3-dioxygenase 148 258 2.7E-23 T 11-11-2016 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 AUP74_RS07545 dca0491e6efc9f080720e96fbae472cc 260 Pfam PF03301 Tryptophan 2,3-dioxygenase 3 128 8.7E-41 T 11-11-2016 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 AUP74_RS16030 5ddb39e8a01e803b25952095e80eba8b 679 Pfam PF13559 Domain of unknown function (DUF4129) 589 658 3.6E-11 T 11-11-2016 IPR025403 Domain of unknown function DUF4129 AUP74_RS16030 5ddb39e8a01e803b25952095e80eba8b 679 SMART SM00460 409 480 1.8E-18 T 11-11-2016 IPR002931 Transglutaminase-like AUP74_RS16030 5ddb39e8a01e803b25952095e80eba8b 679 Pfam PF11992 Domain of unknown function (DUF3488) 13 333 2.9E-92 T 11-11-2016 IPR021878 Protein of unknown function DUF3488 AUP74_RS16030 5ddb39e8a01e803b25952095e80eba8b 679 SUPERFAMILY SSF54001 282 609 1.18E-62 T 11-11-2016 AUP74_RS16030 5ddb39e8a01e803b25952095e80eba8b 679 Pfam PF01841 Transglutaminase-like superfamily 363 478 1.2E-25 T 11-11-2016 IPR002931 Transglutaminase-like AUP74_RS16030 5ddb39e8a01e803b25952095e80eba8b 679 Gene3D G3DSA:3.90.260.10 304 602 6.5E-48 T 11-11-2016 IPR002931 Transglutaminase-like AUP74_RS14620 78a2db1128fb9fa322a01f2dfdd4bceb 466 Pfam PF14535 AMP-binding enzyme C-terminal domain 367 464 3.0E-12 T 11-11-2016 IPR028154 AMP-dependent ligase, C-terminal AUP74_RS14620 78a2db1128fb9fa322a01f2dfdd4bceb 466 SUPERFAMILY SSF56801 71 415 2.62E-29 T 11-11-2016 AUP74_RS14620 78a2db1128fb9fa322a01f2dfdd4bceb 466 Gene3D G3DSA:3.30.300.30 357 464 6.4E-15 T 11-11-2016 AUP74_RS14125 f5ef3440063813efb1b45dde0a64f679 902 SUPERFAMILY SSF52922 712 880 1.38E-39 T 11-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 AUP74_RS14125 f5ef3440063813efb1b45dde0a64f679 902 Gene3D G3DSA:3.40.50.970 475 707 6.1E-108 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS14125 f5ef3440063813efb1b45dde0a64f679 902 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 10 883 0.0 T 11-11-2016 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 AUP74_RS14125 f5ef3440063813efb1b45dde0a64f679 902 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 143 299 1.0E-4 T 11-11-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AUP74_RS14125 f5ef3440063813efb1b45dde0a64f679 902 SUPERFAMILY SSF52518 60 469 1.01E-111 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS14125 f5ef3440063813efb1b45dde0a64f679 902 SUPERFAMILY SSF52518 476 703 1.86E-88 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS14125 f5ef3440063813efb1b45dde0a64f679 902 PIRSF PIRSF000156 1 892 0.0 T 11-11-2016 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 AUP74_RS14125 f5ef3440063813efb1b45dde0a64f679 902 Gene3D G3DSA:3.40.50.970 60 473 3.5E-127 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold AUP74_RS14125 f5ef3440063813efb1b45dde0a64f679 902 Gene3D G3DSA:3.40.50.920 714 877 4.5E-56 T 11-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 AUP74_RS11700 98b89c66b65e636f33af76c47819f076 313 SUPERFAMILY SSF53686 14 301 2.72E-52 T 11-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme AUP74_RS11700 98b89c66b65e636f33af76c47819f076 313 PIRSF PIRSF006278 5 309 9.0E-73 T 11-11-2016 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase AUP74_RS11700 98b89c66b65e636f33af76c47819f076 313 Gene3D G3DSA:3.40.50.1100 93 301 8.6E-38 T 11-11-2016 AUP74_RS11700 98b89c66b65e636f33af76c47819f076 313 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 293 1.9E-18 T 11-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme AUP74_RS07220 f46cdcae5d11d3052f490468114cbd43 163 Pfam PF10369 Small subunit of acetolactate synthase 84 157 1.2E-25 T 11-11-2016 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 AUP74_RS07220 f46cdcae5d11d3052f490468114cbd43 163 SUPERFAMILY SSF55021 2 76 8.91E-22 T 11-11-2016 AUP74_RS07220 f46cdcae5d11d3052f490468114cbd43 163 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 1 158 5.5E-63 T 11-11-2016 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 AUP74_RS07220 f46cdcae5d11d3052f490468114cbd43 163 Gene3D G3DSA:3.30.70.1150 83 162 2.1E-28 T 11-11-2016 AUP74_RS07220 f46cdcae5d11d3052f490468114cbd43 163 SUPERFAMILY SSF55021 79 162 2.14E-25 T 11-11-2016 AUP74_RS07220 f46cdcae5d11d3052f490468114cbd43 163 Pfam PF13710 ACT domain 12 72 4.3E-16 T 11-11-2016 AUP74_RS07220 f46cdcae5d11d3052f490468114cbd43 163 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 76 3.0E-31 T 11-11-2016 AUP74_RS07220 f46cdcae5d11d3052f490468114cbd43 163 Gene3D G3DSA:3.30.70.260 1 78 8.4E-36 T 11-11-2016 AUP74_RS07820 42e7e6b13331360722b1f921fe963d56 223 Pfam PF07719 Tetratricopeptide repeat 160 191 2.7E-5 T 11-11-2016 IPR013105 Tetratricopeptide repeat 2 AUP74_RS07820 42e7e6b13331360722b1f921fe963d56 223 SMART SM00028 160 193 2.6E-4 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS07820 42e7e6b13331360722b1f921fe963d56 223 SMART SM00028 25 58 28.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS07820 42e7e6b13331360722b1f921fe963d56 223 Pfam PF13432 Tetratricopeptide repeat 31 97 0.0037 T 11-11-2016 AUP74_RS07820 42e7e6b13331360722b1f921fe963d56 223 Gene3D G3DSA:1.25.40.10 32 98 2.3E-11 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS07820 42e7e6b13331360722b1f921fe963d56 223 Gene3D G3DSA:1.25.40.10 150 193 2.3E-11 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS07820 42e7e6b13331360722b1f921fe963d56 223 SUPERFAMILY SSF48452 23 60 6.22E-10 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS07820 42e7e6b13331360722b1f921fe963d56 223 SUPERFAMILY SSF48452 110 196 6.22E-10 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS05725 1ba25fd3d19fda04bbfc7dbbda6141e0 358 PIRSF PIRSF019169 2 357 4.9E-121 T 11-11-2016 IPR005883 Type IV pilus assembly protein PilM AUP74_RS05725 1ba25fd3d19fda04bbfc7dbbda6141e0 358 Gene3D G3DSA:3.30.420.40 13 106 3.0E-9 T 11-11-2016 AUP74_RS05725 1ba25fd3d19fda04bbfc7dbbda6141e0 358 TIGRFAM TIGR01175 pilM: type IV pilus assembly protein PilM 13 355 3.3E-120 T 11-11-2016 IPR005883 Type IV pilus assembly protein PilM AUP74_RS05725 1ba25fd3d19fda04bbfc7dbbda6141e0 358 Pfam PF11104 Type IV pilus assembly protein PilM; 16 355 1.8E-134 T 11-11-2016 IPR005883 Type IV pilus assembly protein PilM AUP74_RS05725 1ba25fd3d19fda04bbfc7dbbda6141e0 358 SMART SM00842 14 181 6.2E-5 T 11-11-2016 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 AUP74_RS05725 1ba25fd3d19fda04bbfc7dbbda6141e0 358 Gene3D G3DSA:3.30.420.40 197 318 1.3E-24 T 11-11-2016 AUP74_RS05725 1ba25fd3d19fda04bbfc7dbbda6141e0 358 SUPERFAMILY SSF53067 192 354 9.98E-25 T 11-11-2016 AUP74_RS05725 1ba25fd3d19fda04bbfc7dbbda6141e0 358 SUPERFAMILY SSF53067 15 179 1.62E-13 T 11-11-2016 AUP74_RS02230 8249cd64a90cfe23c56fc19e45b600f5 338 Pfam PF13524 Glycosyl transferases group 1 229 315 2.3E-8 T 11-11-2016 AUP74_RS02085 30a699cc5b5b0f851b9f0ed22271b352 320 SUPERFAMILY SSF53067 1 317 5.94E-50 T 11-11-2016 AUP74_RS02085 30a699cc5b5b0f851b9f0ed22271b352 320 Pfam PF02685 Glucokinase 4 319 2.2E-93 T 11-11-2016 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 AUP74_RS02085 30a699cc5b5b0f851b9f0ed22271b352 320 TIGRFAM TIGR00749 glk: glucokinase 5 315 1.5E-70 T 11-11-2016 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 AUP74_RS02085 30a699cc5b5b0f851b9f0ed22271b352 320 Gene3D G3DSA:3.40.367.20 105 302 4.3E-60 T 11-11-2016 AUP74_RS08540 c24b841e27134b9f8101c7338ea970b0 430 SUPERFAMILY SSF51556 82 391 3.87E-92 T 11-11-2016 IPR032466 Metal-dependent hydrolase AUP74_RS08540 c24b841e27134b9f8101c7338ea970b0 430 Gene3D G3DSA:3.20.20.140 84 387 2.5E-80 T 11-11-2016 AUP74_RS08540 c24b841e27134b9f8101c7338ea970b0 430 Pfam PF01979 Amidohydrolase family 78 427 3.3E-47 T 11-11-2016 IPR006680 Amidohydrolase-related GO:0016787 AUP74_RS08540 c24b841e27134b9f8101c7338ea970b0 430 SUPERFAMILY SSF51338 391 428 4.09E-13 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS08540 c24b841e27134b9f8101c7338ea970b0 430 SUPERFAMILY SSF51338 26 82 4.09E-13 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS08540 c24b841e27134b9f8101c7338ea970b0 430 Gene3D G3DSA:2.30.40.10 391 429 5.7E-25 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS08540 c24b841e27134b9f8101c7338ea970b0 430 Gene3D G3DSA:2.30.40.10 25 83 5.7E-25 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS06465 e2a5d82de37f6a20efcf20defb5cd57c 264 Pfam PF00218 Indole-3-glycerol phosphate synthase 7 255 2.5E-97 T 11-11-2016 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 AUP74_RS06465 e2a5d82de37f6a20efcf20defb5cd57c 264 SUPERFAMILY SSF51366 14 262 6.95E-88 T 11-11-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 AUP74_RS06465 e2a5d82de37f6a20efcf20defb5cd57c 264 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 58 76 - T 11-11-2016 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 AUP74_RS06465 e2a5d82de37f6a20efcf20defb5cd57c 264 Gene3D G3DSA:3.20.20.70 4 263 8.1E-107 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS06465 e2a5d82de37f6a20efcf20defb5cd57c 264 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 5 264 36.142 T 11-11-2016 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 AUP74_RS09295 5ebc7ebff44749a3d9f90b48537831b6 138 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 26 122 1.4E-34 T 11-11-2016 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09295 5ebc7ebff44749a3d9f90b48537831b6 138 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 6 123 20.054 T 11-11-2016 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 AUP74_RS06415 cee7c53778b2f2d73462461cf7230e4d 333 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 37 324 5.4E-107 T 11-11-2016 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 AUP74_RS06415 cee7c53778b2f2d73462461cf7230e4d 333 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 4 328 9.8E-125 T 11-11-2016 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 AUP74_RS06415 cee7c53778b2f2d73462461cf7230e4d 333 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 1 328 36.029 T 11-11-2016 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 AUP74_RS06415 cee7c53778b2f2d73462461cf7230e4d 333 Gene3D G3DSA:3.40.718.10 2 329 8.9E-130 T 11-11-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AUP74_RS06415 cee7c53778b2f2d73462461cf7230e4d 333 SUPERFAMILY SSF53659 3 329 7.36E-113 T 11-11-2016 AUP74_RS08790 ead87d8c4efaf367692e0f08872ead4b 251 PIRSF PIRSF016557 1 247 1.5E-62 T 11-11-2016 IPR016667 Capsular polysaccharide synthesis, CpsB/CapC GO:0004725|GO:0030145 AUP74_RS08790 ead87d8c4efaf367692e0f08872ead4b 251 SUPERFAMILY SSF89550 1 230 4.32E-12 T 11-11-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AUP74_RS06905 bdb85d1b1d01ac2d996bee49677f5064 116 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 4 116 6.7E-42 T 11-11-2016 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06905 bdb85d1b1d01ac2d996bee49677f5064 116 SUPERFAMILY SSF53137 4 114 3.49E-52 T 11-11-2016 AUP74_RS06905 bdb85d1b1d01ac2d996bee49677f5064 116 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 3 116 26.629 T 11-11-2016 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS06905 bdb85d1b1d01ac2d996bee49677f5064 116 Gene3D G3DSA:3.30.420.100 25 116 6.3E-38 T 11-11-2016 AUP74_RS06905 bdb85d1b1d01ac2d996bee49677f5064 116 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 4 116 3.6E-42 T 11-11-2016 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS12995 76edc83afc8dddb55a91c9616f7b85c6 110 Pfam PF02699 Preprotein translocase subunit 24 99 2.3E-28 T 11-11-2016 IPR003849 Preprotein translocase YajC AUP74_RS12995 76edc83afc8dddb55a91c9616f7b85c6 110 SMART SM01323 20 102 8.5E-43 T 11-11-2016 IPR003849 Preprotein translocase YajC AUP74_RS12995 76edc83afc8dddb55a91c9616f7b85c6 110 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 21 102 3.3E-28 T 11-11-2016 IPR003849 Preprotein translocase YajC AUP74_RS12995 76edc83afc8dddb55a91c9616f7b85c6 110 PRINTS PR01853 Bacterial YajC preprotein translocase signature 42 60 3.1E-11 T 11-11-2016 IPR003849 Preprotein translocase YajC AUP74_RS12995 76edc83afc8dddb55a91c9616f7b85c6 110 PRINTS PR01853 Bacterial YajC preprotein translocase signature 22 42 3.1E-11 T 11-11-2016 IPR003849 Preprotein translocase YajC AUP74_RS01810 d3183318028e75c0e75b7263d64160b4 139 Pfam PF09917 Uncharacterized protein conserved in bacteria (DUF2147) 25 137 1.3E-31 T 11-11-2016 IPR019223 Domain of unknown function DUF2147 AUP74_RS11275 4de5b5875d61211f9fe3bb817d6ed637 394 SUPERFAMILY SSF52096 145 251 2.56E-28 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS11275 4de5b5875d61211f9fe3bb817d6ed637 394 SUPERFAMILY SSF52096 282 341 2.56E-28 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS11275 4de5b5875d61211f9fe3bb817d6ed637 394 Pfam PF08496 Peptidase family S49 N-terminal 2 200 8.0E-49 T 11-11-2016 IPR013703 Peptidase S49, N-terminal proteobacteria GO:0004252|GO:0005886 AUP74_RS11275 4de5b5875d61211f9fe3bb817d6ed637 394 Pfam PF01343 Peptidase family S49 204 352 2.0E-45 T 11-11-2016 IPR002142 Peptidase S49 GO:0006508|GO:0008233 AUP74_RS11275 4de5b5875d61211f9fe3bb817d6ed637 394 Gene3D G3DSA:3.90.226.10 143 247 1.6E-31 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS11275 4de5b5875d61211f9fe3bb817d6ed637 394 Gene3D G3DSA:3.90.226.10 313 354 1.6E-31 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS00665 58965cc5a81e40ee11b20ade95692585 933 Pfam PF00593 TonB dependent receptor 586 931 9.6E-26 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS00665 58965cc5a81e40ee11b20ade95692585 933 Gene3D G3DSA:2.40.170.20 471 932 3.4E-70 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS00665 58965cc5a81e40ee11b20ade95692585 933 Gene3D G3DSA:2.40.170.20 274 340 3.4E-70 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS00665 58965cc5a81e40ee11b20ade95692585 933 Gene3D G3DSA:2.40.170.20 375 437 3.4E-70 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS00665 58965cc5a81e40ee11b20ade95692585 933 Gene3D G3DSA:2.40.170.20 168 233 3.4E-70 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS00665 58965cc5a81e40ee11b20ade95692585 933 Pfam PF07715 TonB-dependent Receptor Plug Domain 60 168 8.0E-18 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS00665 58965cc5a81e40ee11b20ade95692585 933 SUPERFAMILY SSF56935 380 441 1.83E-82 T 11-11-2016 AUP74_RS00665 58965cc5a81e40ee11b20ade95692585 933 SUPERFAMILY SSF56935 44 235 1.83E-82 T 11-11-2016 AUP74_RS00665 58965cc5a81e40ee11b20ade95692585 933 SUPERFAMILY SSF56935 292 340 1.83E-82 T 11-11-2016 AUP74_RS00665 58965cc5a81e40ee11b20ade95692585 933 SUPERFAMILY SSF56935 476 628 1.83E-82 T 11-11-2016 AUP74_RS00665 58965cc5a81e40ee11b20ade95692585 933 SUPERFAMILY SSF56935 657 932 1.83E-82 T 11-11-2016 AUP74_RS00665 58965cc5a81e40ee11b20ade95692585 933 Gene3D G3DSA:2.170.130.10 45 167 9.5E-29 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS05210 4f6cc08f6bfc60f64cd0d0fa747bee92 255 SUPERFAMILY SSF53187 57 231 3.77E-5 T 11-11-2016 AUP74_RS01145 35e97266d0b40ba1c50f828c1f300987 230 SMART SM00419 170 218 1.2E-4 T 11-11-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AUP74_RS01145 35e97266d0b40ba1c50f828c1f300987 230 SUPERFAMILY SSF51206 6 142 7.2E-27 T 11-11-2016 IPR018490 Cyclic nucleotide-binding-like AUP74_RS01145 35e97266d0b40ba1c50f828c1f300987 230 SMART SM00100 13 131 1.9E-11 T 11-11-2016 IPR000595 Cyclic nucleotide-binding domain AUP74_RS01145 35e97266d0b40ba1c50f828c1f300987 230 Pfam PF00027 Cyclic nucleotide-binding domain 32 119 1.5E-14 T 11-11-2016 IPR000595 Cyclic nucleotide-binding domain AUP74_RS01145 35e97266d0b40ba1c50f828c1f300987 230 SUPERFAMILY SSF46785 150 227 6.43E-15 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS01145 35e97266d0b40ba1c50f828c1f300987 230 Gene3D G3DSA:2.60.120.10 8 143 9.6E-24 T 11-11-2016 IPR014710 RmlC-like jelly roll fold AUP74_RS01145 35e97266d0b40ba1c50f828c1f300987 230 Pfam PF13545 Crp-like helix-turn-helix domain 152 225 3.6E-13 T 11-11-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AUP74_RS01145 35e97266d0b40ba1c50f828c1f300987 230 Gene3D G3DSA:1.10.10.10 149 227 1.8E-16 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS09235 9e62c8ad21946538259f2a6204cb62e8 508 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 322 334 1.0E-6 T 11-11-2016 AUP74_RS09235 9e62c8ad21946538259f2a6204cb62e8 508 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 230 251 1.0E-6 T 11-11-2016 AUP74_RS09235 9e62c8ad21946538259f2a6204cb62e8 508 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 73 98 1.0E-6 T 11-11-2016 AUP74_RS09235 9e62c8ad21946538259f2a6204cb62e8 508 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 439 458 1.0E-6 T 11-11-2016 AUP74_RS09235 9e62c8ad21946538259f2a6204cb62e8 508 Pfam PF00361 Proton-conducting membrane transporter 131 445 3.8E-60 T 11-11-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09235 9e62c8ad21946538259f2a6204cb62e8 508 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 4 500 17.025 T 11-11-2016 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 AUP74_RS09235 9e62c8ad21946538259f2a6204cb62e8 508 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 7 499 1.6E-103 T 11-11-2016 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 AUP74_RS12065 2352ccb3c698f110da456f26c111e842 870 SUPERFAMILY SSF53732 24 595 5.62E-190 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS12065 2352ccb3c698f110da456f26c111e842 870 Pfam PF00330 Aconitase family (aconitate hydratase) 70 538 4.7E-153 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS12065 2352ccb3c698f110da456f26c111e842 870 Gene3D G3DSA:3.20.19.10 610 862 2.5E-65 T 11-11-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel AUP74_RS12065 2352ccb3c698f110da456f26c111e842 870 Gene3D G3DSA:3.40.1060.10 238 355 2.4E-36 T 11-11-2016 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS12065 2352ccb3c698f110da456f26c111e842 870 Gene3D G3DSA:3.30.499.10 357 551 4.7E-56 T 11-11-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS12065 2352ccb3c698f110da456f26c111e842 870 PRINTS PR00415 Aconitase family signature 162 170 6.0E-31 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS12065 2352ccb3c698f110da456f26c111e842 870 PRINTS PR00415 Aconitase family signature 138 151 6.0E-31 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS12065 2352ccb3c698f110da456f26c111e842 870 PRINTS PR00415 Aconitase family signature 205 220 6.0E-31 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS12065 2352ccb3c698f110da456f26c111e842 870 PRINTS PR00415 Aconitase family signature 281 294 6.0E-31 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS12065 2352ccb3c698f110da456f26c111e842 870 PRINTS PR00415 Aconitase family signature 267 280 6.0E-31 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS12065 2352ccb3c698f110da456f26c111e842 870 PRINTS PR00415 Aconitase family signature 360 374 6.0E-31 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS12065 2352ccb3c698f110da456f26c111e842 870 PRINTS PR00415 Aconitase family signature 191 204 6.0E-31 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS12065 2352ccb3c698f110da456f26c111e842 870 PRINTS PR00415 Aconitase family signature 407 418 6.0E-31 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS12065 2352ccb3c698f110da456f26c111e842 870 PRINTS PR00415 Aconitase family signature 469 482 6.0E-31 T 11-11-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS12065 2352ccb3c698f110da456f26c111e842 870 Gene3D G3DSA:3.30.499.10 22 236 3.9E-60 T 11-11-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS12065 2352ccb3c698f110da456f26c111e842 870 Pfam PF00694 Aconitase C-terminal domain 662 793 4.9E-30 T 11-11-2016 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 AUP74_RS12065 2352ccb3c698f110da456f26c111e842 870 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 29 860 3.1E-289 T 11-11-2016 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3 AUP74_RS12065 2352ccb3c698f110da456f26c111e842 870 TIGRFAM TIGR02333 2met_isocit_dHY: 2-methylisocitrate dehydratase, Fe/S-dependent 2 865 0.0 T 11-11-2016 IPR012708 2-methylisocitrate dehydratase AcnD, Fe/S-dependent GO:0019679 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3 AUP74_RS12065 2352ccb3c698f110da456f26c111e842 870 SUPERFAMILY SSF52016 604 863 1.24E-67 T 11-11-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel AUP74_RS13345 78b102d962d7327be4c9a8495ce91f31 416 SUPERFAMILY SSF111369 58 243 1.7E-21 T 11-11-2016 AUP74_RS13345 78b102d962d7327be4c9a8495ce91f31 416 Gene3D G3DSA:2.40.50.100 69 105 1.9E-7 T 11-11-2016 AUP74_RS13345 78b102d962d7327be4c9a8495ce91f31 416 Gene3D G3DSA:2.40.50.100 184 215 1.9E-7 T 11-11-2016 AUP74_RS13345 78b102d962d7327be4c9a8495ce91f31 416 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 45 376 3.2E-45 T 11-11-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 AUP74_RS13345 78b102d962d7327be4c9a8495ce91f31 416 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 58 282 1.5E-11 T 11-11-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AUP74_RS04490 67fa53e98a91548d25f1b148e4188a26 205 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 32 188 1.5E-23 T 11-11-2016 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 AUP74_RS04490 67fa53e98a91548d25f1b148e4188a26 205 Gene3D G3DSA:3.40.50.620 5 188 1.9E-37 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS04490 67fa53e98a91548d25f1b148e4188a26 205 SUPERFAMILY SSF52402 1 188 2.21E-39 T 11-11-2016 AUP74_RS15405 a86ed0dbfb5cb81c8feeb8e92d43761e 146 Pfam PF04246 Positive regulator of sigma(E), RseC/MucC 8 142 3.9E-25 T 11-11-2016 IPR007359 Positive regulator of sigma(E), RseC/MucC AUP74_RS15405 a86ed0dbfb5cb81c8feeb8e92d43761e 146 PIRSF PIRSF004923 1 146 7.1E-29 T 11-11-2016 IPR026268 Protein RseC AUP74_RS11970 9b0105d9b53e99acc0101f9433e534b1 472 SUPERFAMILY SSF53474 273 330 2.58E-21 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS11970 9b0105d9b53e99acc0101f9433e534b1 472 SUPERFAMILY SSF53474 128 243 2.58E-21 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS11970 9b0105d9b53e99acc0101f9433e534b1 472 Gene3D G3DSA:3.40.50.1820 7 318 6.4E-27 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS11970 9b0105d9b53e99acc0101f9433e534b1 472 SUPERFAMILY SSF53474 28 171 4.12E-14 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS11970 9b0105d9b53e99acc0101f9433e534b1 472 TIGRFAM TIGR01840 esterase_phb: esterase, PHB depolymerase family 34 246 2.2E-51 T 11-11-2016 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 AUP74_RS11970 9b0105d9b53e99acc0101f9433e534b1 472 Pfam PF10503 Esterase PHB depolymerase 35 178 8.3E-21 T 11-11-2016 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 AUP74_RS11970 9b0105d9b53e99acc0101f9433e534b1 472 Pfam PF16403 Domain of unknown function (DUF5011) 340 406 1.0E-13 T 11-11-2016 IPR032179 Domain of unknown function DUF5011 AUP74_RS15205 0eb50c7441f79512eb867024187decae 301 Pfam PF01734 Patatin-like phospholipase 12 79 1.0E-8 T 11-11-2016 IPR002641 Patatin/Phospholipase A2-related GO:0006629 AUP74_RS15205 0eb50c7441f79512eb867024187decae 301 SUPERFAMILY SSF52151 11 279 2.88E-36 T 11-11-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 AUP74_RS03745 10ac11f28c5f2c61873009396f2e1fd8 536 TIGRFAM TIGR01982 UbiB: 2-polyprenylphenol 6-hydroxylase 5 439 6.6E-172 T 11-11-2016 IPR010232 Probable protein kinase UbiB GO:0006744 AUP74_RS03745 10ac11f28c5f2c61873009396f2e1fd8 536 Gene3D G3DSA:3.90.1200.10 244 291 4.3E-4 T 11-11-2016 AUP74_RS03745 10ac11f28c5f2c61873009396f2e1fd8 536 Hamap MF_00414 Probable protein kinase UbiB [ubiB]. 1 535 49.884 T 11-11-2016 IPR010232 Probable protein kinase UbiB GO:0006744 AUP74_RS03745 10ac11f28c5f2c61873009396f2e1fd8 536 SUPERFAMILY SSF56112 89 152 6.44E-47 T 11-11-2016 IPR011009 Protein kinase-like domain AUP74_RS03745 10ac11f28c5f2c61873009396f2e1fd8 536 SUPERFAMILY SSF56112 187 430 6.44E-47 T 11-11-2016 IPR011009 Protein kinase-like domain AUP74_RS03745 10ac11f28c5f2c61873009396f2e1fd8 536 Pfam PF03109 ABC1 family 108 225 1.1E-34 T 11-11-2016 IPR004147 UbiB domain AUP74_RS05770 7ff815fbe881f68ea25648f63d0f7787 359 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 27 36 - T 11-11-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AUP74_RS05770 7ff815fbe881f68ea25648f63d0f7787 359 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 14 350 3.6E-137 T 11-11-2016 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AUP74_RS05770 7ff815fbe881f68ea25648f63d0f7787 359 SUPERFAMILY SSF51726 8 357 9.16E-128 T 11-11-2016 AUP74_RS05770 7ff815fbe881f68ea25648f63d0f7787 359 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 10 352 7.9E-145 T 11-11-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AUP74_RS05770 7ff815fbe881f68ea25648f63d0f7787 359 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 11 354 51.336 T 11-11-2016 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AUP74_RS05770 7ff815fbe881f68ea25648f63d0f7787 359 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 147 163 - T 11-11-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AUP74_RS05770 7ff815fbe881f68ea25648f63d0f7787 359 Gene3D G3DSA:3.20.20.210 6 354 8.7E-161 T 11-11-2016 AUP74_RS09535 fe8ce632f4ebc1c235f5e7a47299117b 467 Gene3D G3DSA:3.40.309.10 236 419 1.2E-65 T 11-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 AUP74_RS09535 fe8ce632f4ebc1c235f5e7a47299117b 467 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 248 259 - T 11-11-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 AUP74_RS09535 fe8ce632f4ebc1c235f5e7a47299117b 467 Pfam PF00171 Aldehyde dehydrogenase family 23 439 3.5E-89 T 11-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 AUP74_RS09535 fe8ce632f4ebc1c235f5e7a47299117b 467 SUPERFAMILY SSF53720 17 447 2.49E-127 T 11-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AUP74_RS09535 fe8ce632f4ebc1c235f5e7a47299117b 467 Gene3D G3DSA:3.40.605.10 11 235 1.6E-59 T 11-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AUP74_RS09535 fe8ce632f4ebc1c235f5e7a47299117b 467 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 220 227 - T 11-11-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 AUP74_RS09535 fe8ce632f4ebc1c235f5e7a47299117b 467 PIRSF PIRSF036492 3 467 4.7E-190 T 11-11-2016 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 AUP74_RS02615 48ec1c8ccd6e8d9d926e5d8c22628ffc 378 Gene3D G3DSA:3.60.70.12 7 375 4.1E-117 T 11-11-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AUP74_RS02615 48ec1c8ccd6e8d9d926e5d8c22628ffc 378 SUPERFAMILY SSF56266 6 376 7.59E-107 T 11-11-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AUP74_RS02615 48ec1c8ccd6e8d9d926e5d8c22628ffc 378 Pfam PF03576 Peptidase family S58 24 350 1.8E-102 T 11-11-2016 IPR005321 Peptidase S58, DmpA AUP74_RS15210 336041f851cea0b1a39ea495aed3b985 141 SUPERFAMILY SSF161084 7 133 9.22E-18 T 11-11-2016 AUP74_RS15210 336041f851cea0b1a39ea495aed3b985 141 Gene3D G3DSA:1.20.120.550 65 139 2.3E-5 T 11-11-2016 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain AUP74_RS15210 336041f851cea0b1a39ea495aed3b985 141 Pfam PF01124 MAPEG family 7 137 2.6E-23 T 11-11-2016 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein AUP74_RS09095 359f8531287906b1aef6fef0b847b0f5 259 SUPERFAMILY SSF75217 11 170 2.88E-39 T 11-11-2016 IPR029028 Alpha/beta knot methyltransferases AUP74_RS09095 359f8531287906b1aef6fef0b847b0f5 259 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 9 248 5.9E-78 T 11-11-2016 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 AUP74_RS09095 359f8531287906b1aef6fef0b847b0f5 259 Pfam PF00588 SpoU rRNA Methylase family 12 161 2.1E-36 T 11-11-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 AUP74_RS09095 359f8531287906b1aef6fef0b847b0f5 259 Gene3D G3DSA:3.40.1280.10 10 166 6.6E-34 T 11-11-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AUP74_RS09095 359f8531287906b1aef6fef0b847b0f5 259 PIRSF PIRSF004808 6 252 6.9E-73 T 11-11-2016 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 AUP74_RS07095 2823c2cb35e672b4ea8a1967e7ea9756 310 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2 285 9.8E-99 T 11-11-2016 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 AUP74_RS07095 2823c2cb35e672b4ea8a1967e7ea9756 310 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 287 38.063 T 11-11-2016 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 AUP74_RS07095 2823c2cb35e672b4ea8a1967e7ea9756 310 Pfam PF02401 LytB protein 3 283 3.9E-92 T 11-11-2016 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 AUP74_RS12750 b67c9c31c7dd374d793f50bd62c1e989 321 PIRSF PIRSF018005 6 321 1.2E-102 T 11-11-2016 IPR017804 Methyltransferase EgtD-like AUP74_RS12750 b67c9c31c7dd374d793f50bd62c1e989 321 SUPERFAMILY SSF53335 69 207 1.04E-8 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS12750 b67c9c31c7dd374d793f50bd62c1e989 321 SUPERFAMILY SSF53335 255 315 1.04E-8 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS12750 b67c9c31c7dd374d793f50bd62c1e989 321 Gene3D G3DSA:3.40.50.150 68 197 1.6E-5 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS12750 b67c9c31c7dd374d793f50bd62c1e989 321 Gene3D G3DSA:3.40.50.150 284 306 1.6E-5 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS12750 b67c9c31c7dd374d793f50bd62c1e989 321 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 193 316 6.1E-42 T 11-11-2016 IPR019257 Histidine-specific methyltransferase, SAM-dependent AUP74_RS12750 b67c9c31c7dd374d793f50bd62c1e989 321 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 18 317 7.6E-114 T 11-11-2016 IPR017804 Methyltransferase EgtD-like AUP74_RS03770 ad8dfa00a37aa33d93ff33734d3e93cd 153 Pfam PF01957 NfeD-like C-terminal, partner-binding 13 152 3.0E-18 T 11-11-2016 IPR002810 NfeD-like, C-terminal domain AUP74_RS03770 ad8dfa00a37aa33d93ff33734d3e93cd 153 Gene3D G3DSA:2.40.50.140 90 152 5.9E-6 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS03770 ad8dfa00a37aa33d93ff33734d3e93cd 153 SUPERFAMILY SSF141322 86 151 6.15E-5 T 11-11-2016 AUP74_RS10250 585e5c36e0c2aca6bece64762c7c1c85 340 Pfam PF00274 Fructose-bisphosphate aldolase class-I 6 336 2.4E-131 T 11-11-2016 IPR000741 Fructose-bisphosphate aldolase, class-I GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS10250 585e5c36e0c2aca6bece64762c7c1c85 340 SUPERFAMILY SSF51569 3 338 1.47E-126 T 11-11-2016 AUP74_RS10250 585e5c36e0c2aca6bece64762c7c1c85 340 Gene3D G3DSA:3.20.20.70 3 332 2.7E-140 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS02365 f915b9d4a355a7910812aea2422f5969 423 Gene3D G3DSA:2.40.440.10 291 338 1.7E-14 T 11-11-2016 AUP74_RS02365 f915b9d4a355a7910812aea2422f5969 423 Gene3D G3DSA:2.40.440.10 184 231 1.7E-14 T 11-11-2016 AUP74_RS02365 f915b9d4a355a7910812aea2422f5969 423 Pfam PF03734 L,D-transpeptidase catalytic domain 187 347 2.9E-31 T 11-11-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 AUP74_RS02365 f915b9d4a355a7910812aea2422f5969 423 SUPERFAMILY SSF141523 289 337 5.1E-22 T 11-11-2016 AUP74_RS02365 f915b9d4a355a7910812aea2422f5969 423 SUPERFAMILY SSF141523 184 240 5.1E-22 T 11-11-2016 AUP74_RS02365 f915b9d4a355a7910812aea2422f5969 423 Gene3D G3DSA:1.10.101.10 83 167 1.8E-13 T 11-11-2016 IPR002477 Peptidoglycan binding-like AUP74_RS02365 f915b9d4a355a7910812aea2422f5969 423 SUPERFAMILY SSF47090 81 167 2.62E-14 T 11-11-2016 IPR002477 Peptidoglycan binding-like AUP74_RS02365 f915b9d4a355a7910812aea2422f5969 423 Pfam PF01471 Putative peptidoglycan binding domain 126 159 4.5E-8 T 11-11-2016 IPR002477 Peptidoglycan binding-like AUP74_RS03430 efda2b4cffcd7171fb43c99a078b2e4a 143 PIRSF PIRSF008546 1 142 9.1E-59 T 11-11-2016 IPR014937 Protein of unknown function DUF1810 AUP74_RS03430 efda2b4cffcd7171fb43c99a078b2e4a 143 SUPERFAMILY SSF140736 3 140 3.66E-59 T 11-11-2016 AUP74_RS03430 efda2b4cffcd7171fb43c99a078b2e4a 143 Pfam PF08837 Protein of unknown function (DUF1810) 5 139 4.8E-60 T 11-11-2016 IPR014937 Protein of unknown function DUF1810 AUP74_RS04050 55a189abe5627facbb4a72b2f33cc715 435 Pfam PF02321 Outer membrane efflux protein 248 421 1.6E-11 T 11-11-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 AUP74_RS04050 55a189abe5627facbb4a72b2f33cc715 435 Pfam PF02321 Outer membrane efflux protein 48 224 5.8E-10 T 11-11-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 AUP74_RS04050 55a189abe5627facbb4a72b2f33cc715 435 Gene3D G3DSA:1.20.1600.10 41 422 3.6E-31 T 11-11-2016 AUP74_RS04050 55a189abe5627facbb4a72b2f33cc715 435 SUPERFAMILY SSF56954 23 422 1.96E-47 T 11-11-2016 AUP74_RS11045 272a4d9fa7ffd6f731011cf91e13c9b2 286 SUPERFAMILY SSF46689 233 282 6.45E-12 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS11045 272a4d9fa7ffd6f731011cf91e13c9b2 286 Gene3D G3DSA:1.10.10.60 233 283 7.8E-14 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS11045 272a4d9fa7ffd6f731011cf91e13c9b2 286 SMART SM00342 198 280 2.1E-20 T 11-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AUP74_RS11045 272a4d9fa7ffd6f731011cf91e13c9b2 286 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 5 158 1.5E-30 T 11-11-2016 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal AUP74_RS11045 272a4d9fa7ffd6f731011cf91e13c9b2 286 Pfam PF12833 Helix-turn-helix domain 205 282 1.9E-17 T 11-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AUP74_RS13020 c822707f311ffe544209167a7bfeb5e7 208 Pfam PF08761 dUTPase 5 158 1.1E-32 T 11-11-2016 IPR014871 dUTPase/dCTP pyrophosphatase KEGG: 00240+3.6.1.12 AUP74_RS13020 c822707f311ffe544209167a7bfeb5e7 208 SUPERFAMILY SSF101386 3 203 3.92E-53 T 11-11-2016 AUP74_RS05275 1bf54ac31a548ad559333a945bf87b03 150 Pfam PF13508 Acetyltransferase (GNAT) domain 39 113 9.2E-11 T 11-11-2016 IPR000182 GNAT domain GO:0008080 AUP74_RS05275 1bf54ac31a548ad559333a945bf87b03 150 SUPERFAMILY SSF55729 38 120 3.37E-15 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS05275 1bf54ac31a548ad559333a945bf87b03 150 Gene3D G3DSA:3.40.630.30 24 116 3.0E-12 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS15770 cfc5a72f3002ae4ced460da501e62ddb 194 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 58 75 - T 11-11-2016 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 AUP74_RS15770 cfc5a72f3002ae4ced460da501e62ddb 194 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 104 119 7.4E-11 T 11-11-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 AUP74_RS15770 cfc5a72f3002ae4ced460da501e62ddb 194 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 119 131 7.4E-11 T 11-11-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 AUP74_RS15770 cfc5a72f3002ae4ced460da501e62ddb 194 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 63 75 7.4E-11 T 11-11-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 AUP74_RS15770 cfc5a72f3002ae4ced460da501e62ddb 194 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 37 52 7.4E-11 T 11-11-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 AUP74_RS15770 cfc5a72f3002ae4ced460da501e62ddb 194 Gene3D G3DSA:2.40.100.10 20 181 2.6E-55 T 11-11-2016 IPR029000 Cyclophilin-like domain AUP74_RS15770 cfc5a72f3002ae4ced460da501e62ddb 194 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 24 180 1.0E-48 T 11-11-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 AUP74_RS15770 cfc5a72f3002ae4ced460da501e62ddb 194 SUPERFAMILY SSF50891 20 180 6.14E-57 T 11-11-2016 IPR029000 Cyclophilin-like domain AUP74_RS13435 cb8b54624089022b7941586913f0889a 461 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 3 457 7.0E-207 T 11-11-2016 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 AUP74_RS13435 cb8b54624089022b7941586913f0889a 461 Pfam PF03315 Serine dehydratase beta chain 4 156 2.5E-58 T 11-11-2016 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 AUP74_RS13435 cb8b54624089022b7941586913f0889a 461 Pfam PF03313 Serine dehydratase alpha chain 185 455 1.3E-106 T 11-11-2016 IPR005130 Serine dehydratase-like, alpha subunit AUP74_RS13435 cb8b54624089022b7941586913f0889a 461 SUPERFAMILY SSF143548 17 157 3.92E-46 T 11-11-2016 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 AUP74_RS13435 cb8b54624089022b7941586913f0889a 461 Gene3D G3DSA:3.30.1330.90 11 157 1.1E-54 T 11-11-2016 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 AUP74_RS12480 d74d048a4058740c7f9a184fe5696bba 694 Gene3D G3DSA:2.170.130.10 29 157 4.8E-17 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS12480 d74d048a4058740c7f9a184fe5696bba 694 Pfam PF00593 TonB dependent receptor 453 691 3.1E-20 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS12480 d74d048a4058740c7f9a184fe5696bba 694 SUPERFAMILY SSF56935 28 694 1.34E-82 T 11-11-2016 AUP74_RS12480 d74d048a4058740c7f9a184fe5696bba 694 Gene3D G3DSA:2.40.170.20 158 694 3.9E-62 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS12480 d74d048a4058740c7f9a184fe5696bba 694 Pfam PF07715 TonB-dependent Receptor Plug Domain 52 158 8.7E-8 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS12480 d74d048a4058740c7f9a184fe5696bba 694 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 41 - T 11-11-2016 IPR010916 TonB box, conserved site AUP74_RS10370 9e794c3399aea043948308f710433775 282 Gene3D G3DSA:3.40.390.10 46 268 4.8E-44 T 11-11-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 AUP74_RS10370 9e794c3399aea043948308f710433775 282 SUPERFAMILY SSF55486 57 270 3.95E-42 T 11-11-2016 AUP74_RS10370 9e794c3399aea043948308f710433775 282 Pfam PF06167 Glucose-regulated metallo-peptidase M90 21 268 3.1E-73 T 11-11-2016 IPR010384 MtfA family AUP74_RS15495 bc225ea2fff9487fd6f8e22e5fa21b62 495 Gene3D G3DSA:2.40.50.140 9 141 1.6E-35 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS15495 bc225ea2fff9487fd6f8e22e5fa21b62 495 PRINTS PR00982 Lysyl-tRNA synthetase signature 186 196 1.1E-38 T 11-11-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AUP74_RS15495 bc225ea2fff9487fd6f8e22e5fa21b62 495 PRINTS PR00982 Lysyl-tRNA synthetase signature 373 389 1.1E-38 T 11-11-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AUP74_RS15495 bc225ea2fff9487fd6f8e22e5fa21b62 495 PRINTS PR00982 Lysyl-tRNA synthetase signature 231 244 1.1E-38 T 11-11-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AUP74_RS15495 bc225ea2fff9487fd6f8e22e5fa21b62 495 PRINTS PR00982 Lysyl-tRNA synthetase signature 202 218 1.1E-38 T 11-11-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AUP74_RS15495 bc225ea2fff9487fd6f8e22e5fa21b62 495 PRINTS PR00982 Lysyl-tRNA synthetase signature 249 266 1.1E-38 T 11-11-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AUP74_RS15495 bc225ea2fff9487fd6f8e22e5fa21b62 495 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 14 491 43.907 T 11-11-2016 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AUP74_RS15495 bc225ea2fff9487fd6f8e22e5fa21b62 495 Gene3D G3DSA:3.30.930.10 144 487 6.0E-123 T 11-11-2016 AUP74_RS15495 bc225ea2fff9487fd6f8e22e5fa21b62 495 Pfam PF00152 tRNA synthetases class II (D, K and N) 149 488 1.3E-82 T 11-11-2016 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AUP74_RS15495 bc225ea2fff9487fd6f8e22e5fa21b62 495 Pfam PF01336 OB-fold nucleic acid binding domain 62 133 2.3E-8 T 11-11-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 AUP74_RS15495 bc225ea2fff9487fd6f8e22e5fa21b62 495 SUPERFAMILY SSF50249 6 142 1.1E-34 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS15495 bc225ea2fff9487fd6f8e22e5fa21b62 495 SUPERFAMILY SSF55681 149 489 3.25E-123 T 11-11-2016 AUP74_RS15495 bc225ea2fff9487fd6f8e22e5fa21b62 495 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 9 491 7.7E-201 T 11-11-2016 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AUP74_RS02050 acec549a5713f7c0199c62b12d61248b 294 Gene3D G3DSA:3.40.50.620 4 131 7.6E-11 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS02050 acec549a5713f7c0199c62b12d61248b 294 SUPERFAMILY SSF52402 4 139 2.15E-12 T 11-11-2016 AUP74_RS02050 acec549a5713f7c0199c62b12d61248b 294 Gene3D G3DSA:3.40.50.620 132 272 8.0E-14 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS02050 acec549a5713f7c0199c62b12d61248b 294 Pfam PF00582 Universal stress protein family 6 138 4.4E-9 T 11-11-2016 IPR006016 UspA GO:0006950 AUP74_RS02050 acec549a5713f7c0199c62b12d61248b 294 Pfam PF00582 Universal stress protein family 184 272 5.2E-11 T 11-11-2016 IPR006016 UspA GO:0006950 AUP74_RS02050 acec549a5713f7c0199c62b12d61248b 294 SUPERFAMILY SSF52402 166 272 5.44E-15 T 11-11-2016 AUP74_RS09065 140a237ff61dde51475f5ad019fbd909 222 Gene3D G3DSA:2.40.70.10 79 207 9.1E-37 T 11-11-2016 IPR021109 Aspartic peptidase domain AUP74_RS09065 140a237ff61dde51475f5ad019fbd909 222 SUPERFAMILY SSF50630 82 213 1.13E-35 T 11-11-2016 IPR021109 Aspartic peptidase domain AUP74_RS09065 140a237ff61dde51475f5ad019fbd909 222 Pfam PF05618 Putative ATP-dependant zinc protease 82 215 3.6E-31 T 11-11-2016 AUP74_RS11330 07549ed6716b88d64b80e2e3666e3880 574 Pfam PF00916 Sulfate permease family 23 405 2.4E-106 T 11-11-2016 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 AUP74_RS11330 07549ed6716b88d64b80e2e3666e3880 574 Pfam PF01740 STAS domain 461 559 2.3E-16 T 11-11-2016 IPR002645 STAS domain AUP74_RS11330 07549ed6716b88d64b80e2e3666e3880 574 Gene3D G3DSA:3.30.750.24 460 567 2.7E-17 T 11-11-2016 IPR002645 STAS domain AUP74_RS11330 07549ed6716b88d64b80e2e3666e3880 574 SUPERFAMILY SSF52091 456 567 2.16E-18 T 11-11-2016 IPR002645 STAS domain AUP74_RS11330 07549ed6716b88d64b80e2e3666e3880 574 TIGRFAM TIGR00815 sulP: sulfate permease 9 551 4.1E-137 T 11-11-2016 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 AUP74_RS08400 87be6ce74c77bd430b2b8da4b1002988 93 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 30 50 - T 11-11-2016 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-936440 AUP74_RS08400 87be6ce74c77bd430b2b8da4b1002988 93 Pfam PF00639 PPIC-type PPIASE domain 12 89 2.8E-22 T 11-11-2016 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 AUP74_RS08400 87be6ce74c77bd430b2b8da4b1002988 93 SUPERFAMILY SSF54534 4 92 2.29E-29 T 11-11-2016 AUP74_RS08400 87be6ce74c77bd430b2b8da4b1002988 93 Gene3D G3DSA:3.10.50.40 3 92 1.0E-34 T 11-11-2016 AUP74_RS12365 236db91d5c7ee0febf3b1d00ced29ba7 161 Pfam PF04612 Type II secretion system (T2SS), protein M 6 159 1.6E-36 T 11-11-2016 IPR007690 Type II secretion system, protein M GO:0006858 AUP74_RS12365 236db91d5c7ee0febf3b1d00ced29ba7 161 SUPERFAMILY SSF103054 86 159 4.32E-16 T 11-11-2016 IPR023229 Type II secretion system protein M, periplasmic domain AUP74_RS12365 236db91d5c7ee0febf3b1d00ced29ba7 161 PIRSF PIRSF006291 2 161 1.2E-28 T 11-11-2016 IPR007690 Type II secretion system, protein M GO:0006858 AUP74_RS12365 236db91d5c7ee0febf3b1d00ced29ba7 161 Gene3D G3DSA:3.30.1360.100 86 159 5.1E-17 T 11-11-2016 IPR023229 Type II secretion system protein M, periplasmic domain AUP74_RS04045 9f33d058640020e49d1dad13d6f057a8 691 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 614 675 3.0E-11 T 11-11-2016 IPR007280 Peptidase, C-terminal, archaeal/bacterial AUP74_RS04045 9f33d058640020e49d1dad13d6f057a8 691 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 503 569 2.0E-14 T 11-11-2016 IPR007280 Peptidase, C-terminal, archaeal/bacterial AUP74_RS04045 9f33d058640020e49d1dad13d6f057a8 691 SUPERFAMILY SSF52743 118 471 4.06E-73 T 11-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AUP74_RS04045 9f33d058640020e49d1dad13d6f057a8 691 Gene3D G3DSA:3.40.50.200 125 471 7.8E-87 T 11-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AUP74_RS04045 9f33d058640020e49d1dad13d6f057a8 691 PRINTS PR00723 Subtilisin serine protease family (S8) signature 412 428 1.3E-16 T 11-11-2016 IPR015500 Peptidase S8, subtilisin-related AUP74_RS04045 9f33d058640020e49d1dad13d6f057a8 691 PRINTS PR00723 Subtilisin serine protease family (S8) signature 167 186 1.3E-16 T 11-11-2016 IPR015500 Peptidase S8, subtilisin-related AUP74_RS04045 9f33d058640020e49d1dad13d6f057a8 691 PRINTS PR00723 Subtilisin serine protease family (S8) signature 232 245 1.3E-16 T 11-11-2016 IPR015500 Peptidase S8, subtilisin-related AUP74_RS04045 9f33d058640020e49d1dad13d6f057a8 691 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 236 246 - T 11-11-2016 IPR022398 Peptidase S8, subtilisin, His-active site AUP74_RS04045 9f33d058640020e49d1dad13d6f057a8 691 Gene3D G3DSA:3.30.70.80 47 124 5.2E-5 T 11-11-2016 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 AUP74_RS04045 9f33d058640020e49d1dad13d6f057a8 691 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 413 423 - T 11-11-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site AUP74_RS04045 9f33d058640020e49d1dad13d6f057a8 691 Pfam PF00082 Subtilase family 167 450 2.8E-46 T 11-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AUP74_RS09800 2d447dab03c27ccdb9b7c244dde057ec 627 SUPERFAMILY SSF55486 52 627 3.99E-208 T 11-11-2016 AUP74_RS09800 2d447dab03c27ccdb9b7c244dde057ec 627 PRINTS PR00791 Peptidyl-dipeptidase A (M2) metalloprotease family signature 494 521 1.2E-76 T 11-11-2016 IPR001548 Peptidase M2, peptidyl-dipeptidase A GO:0006508|GO:0008237|GO:0008241|GO:0016020 AUP74_RS09800 2d447dab03c27ccdb9b7c244dde057ec 627 PRINTS PR00791 Peptidyl-dipeptidase A (M2) metalloprotease family signature 248 275 1.2E-76 T 11-11-2016 IPR001548 Peptidase M2, peptidyl-dipeptidase A GO:0006508|GO:0008237|GO:0008241|GO:0016020 AUP74_RS09800 2d447dab03c27ccdb9b7c244dde057ec 627 PRINTS PR00791 Peptidyl-dipeptidase A (M2) metalloprotease family signature 283 304 1.2E-76 T 11-11-2016 IPR001548 Peptidase M2, peptidyl-dipeptidase A GO:0006508|GO:0008237|GO:0008241|GO:0016020 AUP74_RS09800 2d447dab03c27ccdb9b7c244dde057ec 627 PRINTS PR00791 Peptidyl-dipeptidase A (M2) metalloprotease family signature 459 484 1.2E-76 T 11-11-2016 IPR001548 Peptidase M2, peptidyl-dipeptidase A GO:0006508|GO:0008237|GO:0008241|GO:0016020 AUP74_RS09800 2d447dab03c27ccdb9b7c244dde057ec 627 PRINTS PR00791 Peptidyl-dipeptidase A (M2) metalloprotease family signature 392 408 1.2E-76 T 11-11-2016 IPR001548 Peptidase M2, peptidyl-dipeptidase A GO:0006508|GO:0008237|GO:0008241|GO:0016020 AUP74_RS09800 2d447dab03c27ccdb9b7c244dde057ec 627 PRINTS PR00791 Peptidyl-dipeptidase A (M2) metalloprotease family signature 360 385 1.2E-76 T 11-11-2016 IPR001548 Peptidase M2, peptidyl-dipeptidase A GO:0006508|GO:0008237|GO:0008241|GO:0016020 AUP74_RS09800 2d447dab03c27ccdb9b7c244dde057ec 627 PRINTS PR00791 Peptidyl-dipeptidase A (M2) metalloprotease family signature 522 550 1.2E-76 T 11-11-2016 IPR001548 Peptidase M2, peptidyl-dipeptidase A GO:0006508|GO:0008237|GO:0008241|GO:0016020 AUP74_RS09800 2d447dab03c27ccdb9b7c244dde057ec 627 PRINTS PR00791 Peptidyl-dipeptidase A (M2) metalloprotease family signature 420 440 1.2E-76 T 11-11-2016 IPR001548 Peptidase M2, peptidyl-dipeptidase A GO:0006508|GO:0008237|GO:0008241|GO:0016020 AUP74_RS09800 2d447dab03c27ccdb9b7c244dde057ec 627 Pfam PF01401 Angiotensin-converting enzyme 53 626 1.2E-211 T 11-11-2016 IPR001548 Peptidase M2, peptidyl-dipeptidase A GO:0006508|GO:0008237|GO:0008241|GO:0016020 AUP74_RS09110 c95b9bbb34b2ec7edc43ce601b193e53 135 Gene3D G3DSA:3.90.1010.10 2 131 1.2E-55 T 11-11-2016 AUP74_RS09110 c95b9bbb34b2ec7edc43ce601b193e53 135 TIGRFAM TIGR01999 iscU: FeS cluster assembly scaffold IscU 3 125 1.6E-67 T 11-11-2016 IPR011339 ISC system FeS cluster assembly, IscU scaffold GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 AUP74_RS09110 c95b9bbb34b2ec7edc43ce601b193e53 135 Pfam PF01592 NifU-like N terminal domain 2 126 1.6E-55 T 11-11-2016 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 AUP74_RS09110 c95b9bbb34b2ec7edc43ce601b193e53 135 SUPERFAMILY SSF82649 1 127 3.14E-49 T 11-11-2016 AUP74_RS08600 9986d5bcc35a99575d4ea703835b2a15 171 SUPERFAMILY SSF55729 1 149 1.06E-35 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS08600 9986d5bcc35a99575d4ea703835b2a15 171 Gene3D G3DSA:3.40.630.30 2 165 3.6E-42 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS08600 9986d5bcc35a99575d4ea703835b2a15 171 Pfam PF13302 Acetyltransferase (GNAT) domain 8 147 1.1E-26 T 11-11-2016 IPR000182 GNAT domain GO:0008080 AUP74_RS14600 f51645a3f7885afaa797c76e17644e60 395 SUPERFAMILY SSF53335 176 359 2.61E-35 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS14600 f51645a3f7885afaa797c76e17644e60 395 Pfam PF13649 Methyltransferase domain 202 299 2.9E-19 T 11-11-2016 AUP74_RS14600 f51645a3f7885afaa797c76e17644e60 395 Gene3D G3DSA:3.40.50.150 178 359 5.0E-30 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS00030 a3a78ad505751903fa0363c9d4145f9a 153 Gene3D G3DSA:3.40.930.10 1 144 4.1E-40 T 11-11-2016 IPR002178 PTS EIIA type-2 domain AUP74_RS00030 a3a78ad505751903fa0363c9d4145f9a 153 SUPERFAMILY SSF55804 1 145 4.58E-37 T 11-11-2016 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 AUP74_RS00030 a3a78ad505751903fa0363c9d4145f9a 153 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 6 143 2.0E-34 T 11-11-2016 IPR002178 PTS EIIA type-2 domain AUP74_RS00030 a3a78ad505751903fa0363c9d4145f9a 153 TIGRFAM TIGR01419 nitro_reg_IIA: PTS IIA-like nitrogen-regulatory protein PtsN 3 145 1.9E-43 T 11-11-2016 IPR006320 Phosphotransferase system, IIA-like nitrogen-regulatory protein PtsN GO:0008982|GO:0009401 AUP74_RS02325 b9761f1e4d2d0400e387a4a3ff19c800 175 Pfam PF01618 MotA/TolQ/ExbB proton channel family 69 168 4.0E-24 T 11-11-2016 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 AUP74_RS03750 b5b5ebc8a291d9ec1262d0f9894f26c0 208 Pfam PF02036 SCP-2 sterol transfer family 18 112 3.8E-9 T 11-11-2016 IPR003033 SCP2 sterol-binding domain AUP74_RS11220 bff86bd86c45b1b66ff6007cbb1dbb6d 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 1.6E-19 T 11-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 AUP74_RS11220 bff86bd86c45b1b66ff6007cbb1dbb6d 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 1.6E-19 T 11-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 AUP74_RS11220 bff86bd86c45b1b66ff6007cbb1dbb6d 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 1.6E-19 T 11-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 AUP74_RS11220 bff86bd86c45b1b66ff6007cbb1dbb6d 90 SMART SM00411 1 90 1.8E-43 T 11-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 AUP74_RS11220 bff86bd86c45b1b66ff6007cbb1dbb6d 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 11-11-2016 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 AUP74_RS11220 bff86bd86c45b1b66ff6007cbb1dbb6d 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 4.2E-34 T 11-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 AUP74_RS11220 bff86bd86c45b1b66ff6007cbb1dbb6d 90 Gene3D G3DSA:4.10.520.10 1 90 1.2E-37 T 11-11-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 AUP74_RS11220 bff86bd86c45b1b66ff6007cbb1dbb6d 90 SUPERFAMILY SSF47729 1 90 2.06E-32 T 11-11-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 AUP74_RS09075 4f426950b31bd2cf2274d10cbd8f0a51 339 Pfam PF14397 Sugar-transfer associated ATP-grasp 34 306 1.2E-102 T 11-11-2016 AUP74_RS09075 4f426950b31bd2cf2274d10cbd8f0a51 339 Gene3D G3DSA:3.30.1490.20 50 114 6.2E-5 T 11-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 AUP74_RS09075 4f426950b31bd2cf2274d10cbd8f0a51 339 SUPERFAMILY SSF56059 244 292 5.01E-20 T 11-11-2016 AUP74_RS09075 4f426950b31bd2cf2274d10cbd8f0a51 339 SUPERFAMILY SSF56059 55 214 5.01E-20 T 11-11-2016 AUP74_RS09075 4f426950b31bd2cf2274d10cbd8f0a51 339 Gene3D G3DSA:3.30.470.20 174 216 9.9E-4 T 11-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 AUP74_RS09075 4f426950b31bd2cf2274d10cbd8f0a51 339 Gene3D G3DSA:3.30.470.20 248 293 4.9E-4 T 11-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 AUP74_RS09075 4f426950b31bd2cf2274d10cbd8f0a51 339 TIGRFAM TIGR02291 rimK_rel_E_lig: alpha-L-glutamate ligase homolog 21 330 2.1E-130 T 11-11-2016 IPR011758 Alpha-L-glutamate ligase-related protein AUP74_RS02920 705e1b900623c302d673e98528bf7d3a 257 Pfam PF11101 Protein of unknown function (DUF2884) 27 254 3.7E-34 T 11-11-2016 IPR021307 Protein of unknown function DUF2884 AUP74_RS07470 50411e3571c8411a65afa756b90c542d 63 SUPERFAMILY SSF47413 2 61 1.47E-17 T 11-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AUP74_RS07470 50411e3571c8411a65afa756b90c542d 63 SMART SM00530 4 59 1.9E-16 T 11-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AUP74_RS07470 50411e3571c8411a65afa756b90c542d 63 Pfam PF01381 Helix-turn-helix 5 58 3.5E-16 T 11-11-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AUP74_RS07470 50411e3571c8411a65afa756b90c542d 63 Gene3D G3DSA:1.10.260.40 1 61 9.1E-23 T 11-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AUP74_RS16610 70fc292515df753fc617591b6a34ed2c 767 SUPERFAMILY SSF50494 237 322 1.79E-23 T 11-11-2016 IPR009003 Peptidase S1, PA clan AUP74_RS16610 70fc292515df753fc617591b6a34ed2c 767 SUPERFAMILY SSF50494 683 743 1.79E-23 T 11-11-2016 IPR009003 Peptidase S1, PA clan AUP74_RS16610 70fc292515df753fc617591b6a34ed2c 767 SUPERFAMILY SSF50494 74 113 1.79E-23 T 11-11-2016 IPR009003 Peptidase S1, PA clan AUP74_RS16610 70fc292515df753fc617591b6a34ed2c 767 Gene3D G3DSA:2.40.10.10 668 738 2.2E-10 T 11-11-2016 AUP74_RS16610 70fc292515df753fc617591b6a34ed2c 767 Pfam PF10459 Peptidase S46 50 755 6.9E-267 T 11-11-2016 IPR019500 Peptidase S46 GO:0008239|GO:0070009 AUP74_RS06775 9305e20610f20a007e55e8112b16ec76 164 Pfam PF00466 Ribosomal protein L10 6 101 6.4E-26 T 11-11-2016 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 AUP74_RS06775 9305e20610f20a007e55e8112b16ec76 164 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 159 24.209 T 11-11-2016 IPR022973 Ribosomal protein L10 AUP74_RS06775 9305e20610f20a007e55e8112b16ec76 164 SUPERFAMILY SSF160369 5 159 8.11E-45 T 11-11-2016 AUP74_RS06775 9305e20610f20a007e55e8112b16ec76 164 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 72 154 5.0E-4 T 11-11-2016 AUP74_RS06775 9305e20610f20a007e55e8112b16ec76 164 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 11-11-2016 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS06405 215d8306a5b22a2eb5dcc70a6cbe10c0 270 Pfam PF00149 Calcineurin-like phosphoesterase 4 146 2.1E-14 T 11-11-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 AUP74_RS06405 215d8306a5b22a2eb5dcc70a6cbe10c0 270 Gene3D G3DSA:3.60.21.10 169 264 2.0E-55 T 11-11-2016 IPR029052 Metallo-dependent phosphatase-like AUP74_RS06405 215d8306a5b22a2eb5dcc70a6cbe10c0 270 Gene3D G3DSA:3.60.21.10 3 131 2.0E-55 T 11-11-2016 IPR029052 Metallo-dependent phosphatase-like AUP74_RS06405 215d8306a5b22a2eb5dcc70a6cbe10c0 270 TIGRFAM TIGR00668 apaH: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) 1 265 1.2E-81 T 11-11-2016 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 AUP74_RS06405 215d8306a5b22a2eb5dcc70a6cbe10c0 270 SUPERFAMILY SSF56300 3 258 1.04E-56 T 11-11-2016 IPR029052 Metallo-dependent phosphatase-like AUP74_RS06405 215d8306a5b22a2eb5dcc70a6cbe10c0 270 PIRSF PIRSF000903 1 269 1.3E-103 T 11-11-2016 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 AUP74_RS11215 b622df6a66b35a080034e8e66a801350 801 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 10 201 4.1E-45 T 11-11-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 AUP74_RS11215 b622df6a66b35a080034e8e66a801350 801 SUPERFAMILY SSF52540 312 587 9.27E-49 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11215 b622df6a66b35a080034e8e66a801350 801 Gene3D G3DSA:1.10.8.60 501 584 7.7E-32 T 11-11-2016 AUP74_RS11215 b622df6a66b35a080034e8e66a801350 801 TIGRFAM TIGR00763 lon: endopeptidase La 12 771 6.7E-303 T 11-11-2016 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 AUP74_RS11215 b622df6a66b35a080034e8e66a801350 801 PIRSF PIRSF001174 1 775 0.0 T 11-11-2016 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 AUP74_RS11215 b622df6a66b35a080034e8e66a801350 801 SUPERFAMILY SSF54211 595 770 4.93E-57 T 11-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold AUP74_RS11215 b622df6a66b35a080034e8e66a801350 801 Gene3D G3DSA:3.40.50.300 310 500 1.6E-32 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11215 b622df6a66b35a080034e8e66a801350 801 SMART SM00464 10 202 1.3E-81 T 11-11-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 AUP74_RS11215 b622df6a66b35a080034e8e66a801350 801 SUPERFAMILY SSF88697 11 201 3.23E-51 T 11-11-2016 IPR015947 PUA-like domain AUP74_RS11215 b622df6a66b35a080034e8e66a801350 801 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 570 772 5.6E-93 T 11-11-2016 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 AUP74_RS11215 b622df6a66b35a080034e8e66a801350 801 SMART SM00382 348 494 2.3E-11 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS11215 b622df6a66b35a080034e8e66a801350 801 Hamap MF_01973 Lon protease [lon]. 11 772 71.609 T 11-11-2016 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 AUP74_RS11215 b622df6a66b35a080034e8e66a801350 801 Gene3D G3DSA:3.30.230.10 590 771 7.8E-74 T 11-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AUP74_RS11215 b622df6a66b35a080034e8e66a801350 801 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 676 684 - T 11-11-2016 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 AUP74_RS11215 b622df6a66b35a080034e8e66a801350 801 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 352 488 2.4E-16 T 11-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 AUP74_RS11215 b622df6a66b35a080034e8e66a801350 801 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 673 692 1.2E-54 T 11-11-2016 AUP74_RS11215 b622df6a66b35a080034e8e66a801350 801 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 703 722 1.2E-54 T 11-11-2016 AUP74_RS11215 b622df6a66b35a080034e8e66a801350 801 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 356 375 1.2E-54 T 11-11-2016 AUP74_RS11215 b622df6a66b35a080034e8e66a801350 801 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 726 744 1.2E-54 T 11-11-2016 AUP74_RS11215 b622df6a66b35a080034e8e66a801350 801 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 595 611 1.2E-54 T 11-11-2016 AUP74_RS12435 356185bc5e17cf32f0b9645610eb8743 324 Pfam PF13244 Domain of unknown function (DUF4040) 4 65 2.0E-16 T 11-11-2016 IPR025383 Domain of unknown function DUF4040 AUP74_RS12435 356185bc5e17cf32f0b9645610eb8743 324 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 183 304 2.0E-25 T 11-11-2016 IPR007182 Na+/H+ antiporter MnhB subunit-related protein AUP74_RS08320 7ac17dfcd79707baff611f7bbbf33ede 260 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 181 214 1.6E-8 T 11-11-2016 IPR001451 Hexapeptide repeat AUP74_RS08320 7ac17dfcd79707baff611f7bbbf33ede 260 SMART SM00971 1 101 1.0E-46 T 11-11-2016 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 AUP74_RS08320 7ac17dfcd79707baff611f7bbbf33ede 260 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 70 230 6.4E-69 T 11-11-2016 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 AUP74_RS08320 7ac17dfcd79707baff611f7bbbf33ede 260 Pfam PF06426 Serine acetyltransferase, N-terminal 1 101 8.6E-36 T 11-11-2016 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 AUP74_RS08320 7ac17dfcd79707baff611f7bbbf33ede 260 Gene3D G3DSA:1.10.3130.10 1 126 1.8E-47 T 11-11-2016 AUP74_RS08320 7ac17dfcd79707baff611f7bbbf33ede 260 SUPERFAMILY SSF51161 4 248 8.73E-62 T 11-11-2016 IPR011004 Trimeric LpxA-like AUP74_RS08320 7ac17dfcd79707baff611f7bbbf33ede 260 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 190 218 - T 11-11-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 AUP74_RS08320 7ac17dfcd79707baff611f7bbbf33ede 260 Gene3D G3DSA:2.160.10.10 127 238 4.9E-29 T 11-11-2016 AUP74_RS08605 dc90c856e75d900ebf787977c9532f23 788 Gene3D G3DSA:3.40.50.1110 360 468 1.8E-29 T 11-11-2016 IPR013830 SGNH hydrolase-type esterase domain AUP74_RS08605 dc90c856e75d900ebf787977c9532f23 788 Gene3D G3DSA:3.40.50.1110 152 322 1.8E-29 T 11-11-2016 IPR013830 SGNH hydrolase-type esterase domain AUP74_RS08605 dc90c856e75d900ebf787977c9532f23 788 Gene3D G3DSA:3.40.50.1110 22 59 1.8E-29 T 11-11-2016 IPR013830 SGNH hydrolase-type esterase domain AUP74_RS08605 dc90c856e75d900ebf787977c9532f23 788 SUPERFAMILY SSF52266 441 464 6.51E-5 T 11-11-2016 IPR013830 SGNH hydrolase-type esterase domain AUP74_RS08605 dc90c856e75d900ebf787977c9532f23 788 SUPERFAMILY SSF52266 195 318 6.51E-5 T 11-11-2016 IPR013830 SGNH hydrolase-type esterase domain AUP74_RS08605 dc90c856e75d900ebf787977c9532f23 788 SUPERFAMILY SSF52266 348 390 6.51E-5 T 11-11-2016 IPR013830 SGNH hydrolase-type esterase domain AUP74_RS08605 dc90c856e75d900ebf787977c9532f23 788 Pfam PF00657 GDSL-like Lipase/Acylhydrolase 32 461 8.6E-7 T 11-11-2016 IPR001087 GDSL lipase/esterase GO:0016788 AUP74_RS08605 dc90c856e75d900ebf787977c9532f23 788 SMART SM00869 504 782 1.3E-8 T 11-11-2016 IPR005546 Autotransporter beta-domain AUP74_RS08605 dc90c856e75d900ebf787977c9532f23 788 Gene3D G3DSA:2.40.128.130 482 774 3.2E-21 T 11-11-2016 IPR005546 Autotransporter beta-domain AUP74_RS08605 dc90c856e75d900ebf787977c9532f23 788 SUPERFAMILY SSF103515 482 784 8.11E-18 T 11-11-2016 IPR005546 Autotransporter beta-domain AUP74_RS12395 be01903074e1314fd5ed34bcd969385a 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 40 55 5.6E-21 T 11-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AUP74_RS12395 be01903074e1314fd5ed34bcd969385a 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 27 38 5.6E-21 T 11-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AUP74_RS12395 be01903074e1314fd5ed34bcd969385a 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 5.6E-21 T 11-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AUP74_RS12395 be01903074e1314fd5ed34bcd969385a 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 7 22 5.6E-21 T 11-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AUP74_RS12395 be01903074e1314fd5ed34bcd969385a 116 SMART SM00418 5 87 1.9E-27 T 11-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AUP74_RS12395 be01903074e1314fd5ed34bcd969385a 116 Gene3D G3DSA:1.10.10.10 6 81 4.4E-28 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS12395 be01903074e1314fd5ed34bcd969385a 116 SUPERFAMILY SSF46785 2 82 7.22E-25 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS12395 be01903074e1314fd5ed34bcd969385a 116 Pfam PF01022 Bacterial regulatory protein, arsR family 13 58 3.9E-14 T 11-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AUP74_RS14840 d60f294735f639863cd6d9a76941b1dc 251 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 18 194 0.0084 T 11-11-2016 AUP74_RS14840 d60f294735f639863cd6d9a76941b1dc 251 SUPERFAMILY SSF51735 15 249 5.65E-62 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS14840 d60f294735f639863cd6d9a76941b1dc 251 Pfam PF00106 short chain dehydrogenase 18 214 1.5E-48 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS14840 d60f294735f639863cd6d9a76941b1dc 251 Gene3D G3DSA:3.40.50.720 14 251 2.5E-66 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS14840 d60f294735f639863cd6d9a76941b1dc 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 157 185 - T 11-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AUP74_RS14840 d60f294735f639863cd6d9a76941b1dc 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 5.1E-24 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS14840 d60f294735f639863cd6d9a76941b1dc 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 5.1E-24 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS14840 d60f294735f639863cd6d9a76941b1dc 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 5.1E-24 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS14840 d60f294735f639863cd6d9a76941b1dc 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 19 36 5.1E-24 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS14840 d60f294735f639863cd6d9a76941b1dc 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 5.1E-24 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS14840 d60f294735f639863cd6d9a76941b1dc 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 160 5.1E-24 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS04635 2826eb35be0ffb6a5657be7e02873adb 455 Pfam PF13520 Amino acid permease 3 426 1.4E-49 T 11-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 AUP74_RS04635 2826eb35be0ffb6a5657be7e02873adb 455 PIRSF PIRSF006060 1 452 7.9E-68 T 11-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 AUP74_RS02725 3eace8a33a9daaff8821233e1a2bc2a9 918 SUPERFAMILY SSF63737 56 255 9.29E-40 T 11-11-2016 AUP74_RS02725 3eace8a33a9daaff8821233e1a2bc2a9 918 SUPERFAMILY SSF55486 272 517 4.1E-59 T 11-11-2016 AUP74_RS02725 3eace8a33a9daaff8821233e1a2bc2a9 918 Gene3D G3DSA:1.10.390.10 371 518 1.8E-30 T 11-11-2016 AUP74_RS02725 3eace8a33a9daaff8821233e1a2bc2a9 918 Pfam PF11838 ERAP1-like C-terminal domain 583 900 1.7E-37 T 11-11-2016 IPR024571 ERAP1-like C-terminal domain AUP74_RS02725 3eace8a33a9daaff8821233e1a2bc2a9 918 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 238 253 1.4E-16 T 11-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AUP74_RS02725 3eace8a33a9daaff8821233e1a2bc2a9 918 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 377 389 1.4E-16 T 11-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AUP74_RS02725 3eace8a33a9daaff8821233e1a2bc2a9 918 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 190 205 1.4E-16 T 11-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AUP74_RS02725 3eace8a33a9daaff8821233e1a2bc2a9 918 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 358 373 1.4E-16 T 11-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AUP74_RS02725 3eace8a33a9daaff8821233e1a2bc2a9 918 Pfam PF01433 Peptidase family M1 64 449 1.2E-82 T 11-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AUP74_RS07100 2f984a446f9be67c3cd88598b5c61198 165 SUPERFAMILY SSF54523 11 125 2.98E-18 T 11-11-2016 AUP74_RS07100 2f984a446f9be67c3cd88598b5c61198 165 Pfam PF12019 Type II transport protein GspH 47 155 1.1E-11 T 11-11-2016 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 AUP74_RS07100 2f984a446f9be67c3cd88598b5c61198 165 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 9 29 - T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS07100 2f984a446f9be67c3cd88598b5c61198 165 Gene3D G3DSA:3.30.700.10 11 52 5.4E-8 T 11-11-2016 AUP74_RS07100 2f984a446f9be67c3cd88598b5c61198 165 Pfam PF13633 Prokaryotic N-terminal methylation site 9 34 1.1E-7 T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS07100 2f984a446f9be67c3cd88598b5c61198 165 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 31 3.4E-7 T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS08825 0c0219df5c7f37073adf7eed41f04676 145 Gene3D G3DSA:2.160.10.10 35 133 3.1E-28 T 11-11-2016 AUP74_RS08825 0c0219df5c7f37073adf7eed41f04676 145 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 79 114 2.6E-15 T 11-11-2016 IPR001451 Hexapeptide repeat AUP74_RS08825 0c0219df5c7f37073adf7eed41f04676 145 SUPERFAMILY SSF51161 10 133 2.63E-30 T 11-11-2016 IPR011004 Trimeric LpxA-like AUP74_RS08520 746a87de800467ecc47e0ee46f42f5f5 338 Gene3D G3DSA:3.40.367.20 117 320 1.6E-60 T 11-11-2016 AUP74_RS08520 746a87de800467ecc47e0ee46f42f5f5 338 SUPERFAMILY SSF53067 16 334 4.89E-51 T 11-11-2016 AUP74_RS08520 746a87de800467ecc47e0ee46f42f5f5 338 Pfam PF02685 Glucokinase 16 334 1.3E-99 T 11-11-2016 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 AUP74_RS08520 746a87de800467ecc47e0ee46f42f5f5 338 ProSitePatterns PS01125 ROK family signature. 154 181 - T 11-11-2016 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AUP74_RS08520 746a87de800467ecc47e0ee46f42f5f5 338 TIGRFAM TIGR00749 glk: glucokinase 16 331 1.2E-79 T 11-11-2016 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 AUP74_RS15340 38e844585fb4b17b21c94430d8aa1a08 296 TIGRFAM TIGR01138 cysM: cysteine synthase B 5 294 2.7E-148 T 11-11-2016 IPR005858 Cysteine synthase CysM GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 AUP74_RS15340 38e844585fb4b17b21c94430d8aa1a08 296 SUPERFAMILY SSF53686 3 293 3.4E-91 T 11-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme AUP74_RS15340 38e844585fb4b17b21c94430d8aa1a08 296 Gene3D G3DSA:3.40.50.1100 42 142 5.0E-39 T 11-11-2016 AUP74_RS15340 38e844585fb4b17b21c94430d8aa1a08 296 TIGRFAM TIGR01136 cysKM: cysteine synthase 7 294 2.0E-121 T 11-11-2016 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 AUP74_RS15340 38e844585fb4b17b21c94430d8aa1a08 296 Gene3D G3DSA:3.40.50.1100 148 295 4.8E-81 T 11-11-2016 AUP74_RS15340 38e844585fb4b17b21c94430d8aa1a08 296 Gene3D G3DSA:3.40.50.1100 2 41 4.8E-81 T 11-11-2016 AUP74_RS15340 38e844585fb4b17b21c94430d8aa1a08 296 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 7 283 1.4E-66 T 11-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme AUP74_RS15340 38e844585fb4b17b21c94430d8aa1a08 296 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 32 50 - T 11-11-2016 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 AUP74_RS03895 208c10ef4de21cfe1e0831331f040d74 268 Pfam PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 23 144 1.3E-27 T 11-11-2016 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 AUP74_RS03895 208c10ef4de21cfe1e0831331f040d74 268 Gene3D G3DSA:3.10.50.40 127 240 5.6E-46 T 11-11-2016 AUP74_RS03895 208c10ef4de21cfe1e0831331f040d74 268 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 152 238 5.0E-27 T 11-11-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 AUP74_RS03895 208c10ef4de21cfe1e0831331f040d74 268 Gene3D G3DSA:1.10.287.460 28 126 1.5E-22 T 11-11-2016 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 AUP74_RS03895 208c10ef4de21cfe1e0831331f040d74 268 SUPERFAMILY SSF54534 37 240 1.73E-59 T 11-11-2016 AUP74_RS14305 a8250c5af6c16b0b72b4e545dfe18a51 266 Gene3D G3DSA:3.40.50.150 40 147 2.0E-23 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS14305 a8250c5af6c16b0b72b4e545dfe18a51 266 Pfam PF08241 Methyltransferase domain 47 140 2.0E-18 T 11-11-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 AUP74_RS14305 a8250c5af6c16b0b72b4e545dfe18a51 266 SUPERFAMILY SSF53335 26 141 1.45E-23 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS10775 40d33a438ddfd6a883f86516b93afe32 67 Pfam PF07869 Protein of unknown function (DUF1656) 4 58 2.2E-15 T 11-11-2016 IPR012451 Protein of unknown function DUF1656 AUP74_RS12695 6435c821af3daac7a16722446437861c 281 Pfam PF00231 ATP synthase 9 268 1.7E-28 T 11-11-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 AUP74_RS12695 6435c821af3daac7a16722446437861c 281 Gene3D G3DSA:1.10.287.80 208 272 4.2E-14 T 11-11-2016 AUP74_RS12695 6435c821af3daac7a16722446437861c 281 Gene3D G3DSA:1.10.287.80 13 36 4.2E-14 T 11-11-2016 AUP74_RS12695 6435c821af3daac7a16722446437861c 281 Gene3D G3DSA:1.10.287.80 73 92 4.2E-14 T 11-11-2016 AUP74_RS12695 6435c821af3daac7a16722446437861c 281 PRINTS PR00126 ATP synthase gamma subunit signature 252 273 1.9E-6 T 11-11-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 AUP74_RS12695 6435c821af3daac7a16722446437861c 281 PRINTS PR00126 ATP synthase gamma subunit signature 68 87 1.9E-6 T 11-11-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 AUP74_RS12695 6435c821af3daac7a16722446437861c 281 SUPERFAMILY SSF52943 7 271 5.76E-27 T 11-11-2016 IPR023633 ATPase, F1 complex, gamma subunit domain Reactome: R-HSA-163210 AUP74_RS00770 2a09f82f5bb91a4548af66218e004e77 140 Pfam PF03061 Thioesterase superfamily 20 93 4.4E-16 T 11-11-2016 IPR006683 Thioesterase domain Reactome: R-HSA-75105 AUP74_RS00770 2a09f82f5bb91a4548af66218e004e77 140 SUPERFAMILY SSF54637 4 117 1.16E-24 T 11-11-2016 IPR029069 HotDog domain AUP74_RS00770 2a09f82f5bb91a4548af66218e004e77 140 Gene3D G3DSA:3.10.129.10 5 126 9.4E-24 T 11-11-2016 IPR029069 HotDog domain AUP74_RS10085 bcdf6ac1b4b646fc5fbb37703bb2c23b 239 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 7 229 4.0E-62 T 11-11-2016 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 AUP74_RS10085 bcdf6ac1b4b646fc5fbb37703bb2c23b 239 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 103 110 - T 11-11-2016 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 AUP74_RS10085 bcdf6ac1b4b646fc5fbb37703bb2c23b 239 Gene3D G3DSA:3.90.550.10 6 230 4.3E-64 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases AUP74_RS10085 bcdf6ac1b4b646fc5fbb37703bb2c23b 239 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 6 228 6.4E-63 T 11-11-2016 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 AUP74_RS10085 bcdf6ac1b4b646fc5fbb37703bb2c23b 239 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 4 231 29.227 T 11-11-2016 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 AUP74_RS10085 bcdf6ac1b4b646fc5fbb37703bb2c23b 239 SUPERFAMILY SSF53448 5 228 9.97E-52 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases AUP74_RS06615 629b75f0c1246966b362ee0ffb6419e1 602 PRINTS PR00762 Chloride channel signature 132 151 8.6E-17 T 11-11-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AUP74_RS06615 629b75f0c1246966b362ee0ffb6419e1 602 PRINTS PR00762 Chloride channel signature 183 202 8.6E-17 T 11-11-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AUP74_RS06615 629b75f0c1246966b362ee0ffb6419e1 602 PRINTS PR00762 Chloride channel signature 396 415 8.6E-17 T 11-11-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AUP74_RS06615 629b75f0c1246966b362ee0ffb6419e1 602 PRINTS PR00762 Chloride channel signature 378 394 8.6E-17 T 11-11-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AUP74_RS06615 629b75f0c1246966b362ee0ffb6419e1 602 SUPERFAMILY SSF81340 25 436 7.46E-93 T 11-11-2016 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 AUP74_RS06615 629b75f0c1246966b362ee0ffb6419e1 602 Pfam PF00654 Voltage gated chloride channel 90 428 2.7E-82 T 11-11-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AUP74_RS06615 629b75f0c1246966b362ee0ffb6419e1 602 Gene3D G3DSA:1.10.3080.10 35 442 1.1E-80 T 11-11-2016 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 AUP74_RS09300 8bfadfc0a65480b7d9fc662a16b48c94 317 Gene3D G3DSA:2.160.10.10 32 90 2.4E-5 T 11-11-2016 AUP74_RS09300 8bfadfc0a65480b7d9fc662a16b48c94 317 Gene3D G3DSA:2.160.20.10 91 253 5.1E-4 T 11-11-2016 IPR012334 Pectin lyase fold AUP74_RS09300 8bfadfc0a65480b7d9fc662a16b48c94 317 SUPERFAMILY SSF51126 51 256 6.04E-10 T 11-11-2016 IPR011050 Pectin lyase fold/virulence factor AUP74_RS09160 6bd3dd97cda96d3d6f9c60803597fdf2 370 PIRSF PIRSF004640 1 363 5.6E-151 T 11-11-2016 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 AUP74_RS09160 6bd3dd97cda96d3d6f9c60803597fdf2 370 SUPERFAMILY SSF51717 15 207 5.02E-9 T 11-11-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AUP74_RS09160 6bd3dd97cda96d3d6f9c60803597fdf2 370 Pfam PF04551 GcpE protein 13 353 7.8E-138 T 11-11-2016 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 AUP74_RS09160 6bd3dd97cda96d3d6f9c60803597fdf2 370 SUPERFAMILY SSF56014 266 353 2.71E-14 T 11-11-2016 AUP74_RS09160 6bd3dd97cda96d3d6f9c60803597fdf2 370 Gene3D G3DSA:3.20.20.70 31 132 5.5E-10 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS09160 6bd3dd97cda96d3d6f9c60803597fdf2 370 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 7 357 35.657 T 11-11-2016 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 AUP74_RS09160 6bd3dd97cda96d3d6f9c60803597fdf2 370 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 9 352 1.5E-131 T 11-11-2016 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 AUP74_RS07710 9b9d4d4c9bc4aec3bbd4a227e22ab776 350 TIGRFAM TIGR01946 rnfD: electron transport complex, RnfABCDGE type, D subunit 8 338 1.4E-121 T 11-11-2016 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 AUP74_RS07710 9b9d4d4c9bc4aec3bbd4a227e22ab776 350 Hamap MF_00462 Electron transport complex subunit RsxD [rsxD]. 3 339 26.441 T 11-11-2016 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 AUP74_RS07710 9b9d4d4c9bc4aec3bbd4a227e22ab776 350 Pfam PF03116 NQR2, RnfD, RnfE family 7 337 1.2E-99 T 11-11-2016 IPR004338 NADH-quinone reductase NQR2/RnfD GO:0006810|GO:0016020 AUP74_RS06395 c0e9656d29a970a71477c6cecfccba4c 341 SUPERFAMILY SSF51735 1 339 1.19E-96 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS06395 c0e9656d29a970a71477c6cecfccba4c 341 Gene3D G3DSA:3.40.50.720 1 179 5.3E-53 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS06395 c0e9656d29a970a71477c6cecfccba4c 341 Gene3D G3DSA:3.90.25.10 267 340 2.3E-51 T 11-11-2016 AUP74_RS06395 c0e9656d29a970a71477c6cecfccba4c 341 Gene3D G3DSA:3.90.25.10 180 232 2.3E-51 T 11-11-2016 AUP74_RS06395 c0e9656d29a970a71477c6cecfccba4c 341 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 338 1.6E-135 T 11-11-2016 IPR005886 UDP-glucose 4-epimerase GalE GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 AUP74_RS06395 c0e9656d29a970a71477c6cecfccba4c 341 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 327 2.1E-58 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS06020 f5bc133fa159eba1a8e4c56bd8cb71fb 187 Pfam PF13302 Acetyltransferase (GNAT) domain 18 155 7.5E-27 T 11-11-2016 IPR000182 GNAT domain GO:0008080 AUP74_RS06020 f5bc133fa159eba1a8e4c56bd8cb71fb 187 Gene3D G3DSA:3.40.630.30 11 184 3.0E-51 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS06020 f5bc133fa159eba1a8e4c56bd8cb71fb 187 SUPERFAMILY SSF55729 11 180 7.57E-47 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS00580 2891451bf5f78475f761d258304ae145 493 Gene3D G3DSA:1.20.1250.20 73 216 2.6E-19 T 11-11-2016 AUP74_RS00580 2891451bf5f78475f761d258304ae145 493 Gene3D G3DSA:1.20.1250.20 253 452 1.6E-11 T 11-11-2016 AUP74_RS00580 2891451bf5f78475f761d258304ae145 493 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 15 230 2.0E-53 T 11-11-2016 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 AUP74_RS00580 2891451bf5f78475f761d258304ae145 493 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 244 454 3.6E-45 T 11-11-2016 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 AUP74_RS00580 2891451bf5f78475f761d258304ae145 493 SUPERFAMILY SSF103473 18 453 9.81E-37 T 11-11-2016 IPR020846 Major facilitator superfamily domain AUP74_RS00580 2891451bf5f78475f761d258304ae145 493 Pfam PF00854 POT family 100 213 7.8E-30 T 11-11-2016 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 AUP74_RS00580 2891451bf5f78475f761d258304ae145 493 Pfam PF00854 POT family 241 419 5.5E-33 T 11-11-2016 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 AUP74_RS00580 2891451bf5f78475f761d258304ae145 493 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 169 181 - T 11-11-2016 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 AUP74_RS10260 d3a4484202118ca6ee30e30e9844aa92 61 Hamap MF_01187 UPF0434 protein YcaR [ycaR]. 1 54 27.259 T 11-11-2016 IPR005651 Uncharacterised protein family UPF0434/Trm112 AUP74_RS10260 d3a4484202118ca6ee30e30e9844aa92 61 Pfam PF03966 Trm112p-like protein 2 41 6.4E-11 T 11-11-2016 IPR005651 Uncharacterised protein family UPF0434/Trm112 AUP74_RS10260 d3a4484202118ca6ee30e30e9844aa92 61 Gene3D G3DSA:2.20.25.10 8 58 3.8E-27 T 11-11-2016 AUP74_RS10260 d3a4484202118ca6ee30e30e9844aa92 61 SUPERFAMILY SSF158997 1 55 4.71E-21 T 11-11-2016 AUP74_RS13330 8f73e14110595d817b5f3e2d3eedb03c 542 SUPERFAMILY SSF53383 22 456 1.5E-75 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase AUP74_RS13330 8f73e14110595d817b5f3e2d3eedb03c 542 Pfam PF00266 Aminotransferase class-V 33 403 5.0E-41 T 11-11-2016 IPR000192 Aminotransferase class V domain AUP74_RS13330 8f73e14110595d817b5f3e2d3eedb03c 542 Gene3D G3DSA:3.90.1150.10 306 458 1.6E-20 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS13330 8f73e14110595d817b5f3e2d3eedb03c 542 Gene3D G3DSA:3.40.640.10 46 305 5.9E-62 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AUP74_RS13970 382b2760647804c90fb386a9bd371d29 348 Gene3D G3DSA:3.40.50.10740 34 185 5.9E-52 T 11-11-2016 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain AUP74_RS13970 382b2760647804c90fb386a9bd371d29 348 PIRSF PIRSF028757 34 348 1.0E-93 T 11-11-2016 IPR003507 Peptidase family S66 AUP74_RS13970 382b2760647804c90fb386a9bd371d29 348 SUPERFAMILY SSF52317 34 189 1.69E-47 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS13970 382b2760647804c90fb386a9bd371d29 348 Pfam PF02016 LD-carboxypeptidase 46 333 2.4E-87 T 11-11-2016 IPR003507 Peptidase family S66 AUP74_RS13970 382b2760647804c90fb386a9bd371d29 348 Gene3D G3DSA:3.50.30.60 211 339 2.2E-48 T 11-11-2016 IPR027461 LD-carboxypeptidase A, C-terminal domain AUP74_RS13970 382b2760647804c90fb386a9bd371d29 348 SUPERFAMILY SSF141986 206 338 5.75E-46 T 11-11-2016 IPR027461 LD-carboxypeptidase A, C-terminal domain AUP74_RS01775 4986cf08863ed07e2624a0805d16b596 640 Gene3D G3DSA:2.120.10.30 515 595 1.8E-5 T 11-11-2016 IPR011042 Six-bladed beta-propeller, TolB-like AUP74_RS01775 4986cf08863ed07e2624a0805d16b596 640 Pfam PF05787 Bacterial protein of unknown function (DUF839) 45 599 1.5E-159 T 11-11-2016 IPR008557 Protein of unknown function DUF839 AUP74_RS01775 4986cf08863ed07e2624a0805d16b596 640 SUPERFAMILY SSF63829 428 474 2.16E-7 T 11-11-2016 AUP74_RS01775 4986cf08863ed07e2624a0805d16b596 640 SUPERFAMILY SSF63829 306 354 2.16E-7 T 11-11-2016 AUP74_RS01775 4986cf08863ed07e2624a0805d16b596 640 SUPERFAMILY SSF63829 523 614 2.16E-7 T 11-11-2016 AUP74_RS01775 4986cf08863ed07e2624a0805d16b596 640 SUPERFAMILY SSF63829 385 396 2.16E-7 T 11-11-2016 AUP74_RS05395 3967c7a5e81cc25cf915e345a7ebb245 160 Pfam PF04191 Phospholipid methyltransferase 49 149 4.8E-18 T 11-11-2016 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 AUP74_RS05395 3967c7a5e81cc25cf915e345a7ebb245 160 ProDom PD049902 METHYLTRANSFERASE TRANSFERASE PRECURSOR ISOPRENYLCYSTEINE SIGNAL CARBOXYL TRANSMEMBRANE MEMBRANE FAMILY XCC3183 134 160 0.002 T 11-11-2016 AUP74_RS10400 6b8e20856e29a365ed4aed07f2c6b325 139 Gene3D G3DSA:3.30.700.10 6 113 1.8E-18 T 11-11-2016 AUP74_RS10400 6b8e20856e29a365ed4aed07f2c6b325 139 Pfam PF16732 Type IV minor pilin ComP, DNA uptake sequence receptor 27 122 2.5E-21 T 11-11-2016 IPR031982 Type IV minor pilin ComP AUP74_RS10400 6b8e20856e29a365ed4aed07f2c6b325 139 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 26 1.5E-9 T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS10400 6b8e20856e29a365ed4aed07f2c6b325 139 SUPERFAMILY SSF54523 6 131 1.15E-25 T 11-11-2016 AUP74_RS10400 6b8e20856e29a365ed4aed07f2c6b325 139 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 4 24 - T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS10400 6b8e20856e29a365ed4aed07f2c6b325 139 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 2 25 6.2E-9 T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS10400 6b8e20856e29a365ed4aed07f2c6b325 139 PRINTS PR00885 Bacterial general secretion pathway protein H signature 122 137 7.7E-5 T 11-11-2016 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 AUP74_RS10400 6b8e20856e29a365ed4aed07f2c6b325 139 PRINTS PR00885 Bacterial general secretion pathway protein H signature 16 30 7.7E-5 T 11-11-2016 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 AUP74_RS10400 6b8e20856e29a365ed4aed07f2c6b325 139 PRINTS PR00885 Bacterial general secretion pathway protein H signature 1 15 7.7E-5 T 11-11-2016 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 AUP74_RS05780 3dba1cc59d29eb33c2416566cb003825 287 Pfam PF02666 Phosphatidylserine decarboxylase 63 280 1.2E-63 T 11-11-2016 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 AUP74_RS05780 3dba1cc59d29eb33c2416566cb003825 287 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 49 280 1.5E-83 T 11-11-2016 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 AUP74_RS05780 3dba1cc59d29eb33c2416566cb003825 287 Hamap MF_00662 Phosphatidylserine decarboxylase proenzyme [psd]. 10 283 46.932 T 11-11-2016 IPR033178 Phosphatidylserine decarboxylase, prokaryotic type 1 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 AUP74_RS03725 117411fb73177c958bc567d548c3f2f2 170 Pfam PF02416 mttA/Hcf106 family 4 31 1.1E-4 T 11-11-2016 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 AUP74_RS03725 117411fb73177c958bc567d548c3f2f2 170 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 2 71 4.1E-25 T 11-11-2016 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 AUP74_RS03725 117411fb73177c958bc567d548c3f2f2 170 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 5.0E-19 T 11-11-2016 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 AUP74_RS03725 117411fb73177c958bc567d548c3f2f2 170 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 5.0E-19 T 11-11-2016 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 AUP74_RS03725 117411fb73177c958bc567d548c3f2f2 170 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 40 58 5.0E-19 T 11-11-2016 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 AUP74_RS03725 117411fb73177c958bc567d548c3f2f2 170 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 1 134 16.14 T 11-11-2016 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 AUP74_RS00795 b103a4e4c4771ea8a0641a8dc1480c07 437 Pfam PF02687 FtsX-like permease family 314 430 3.8E-17 T 11-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 AUP74_RS00795 b103a4e4c4771ea8a0641a8dc1480c07 437 Pfam PF12704 MacB-like periplasmic core domain 20 271 1.8E-19 T 11-11-2016 IPR025857 MacB-like periplasmic core domain AUP74_RS16590 02eba009c3b63154bac897d451114e12 76 SUPERFAMILY SSF140376 2 75 1.31E-27 T 11-11-2016 AUP74_RS16590 02eba009c3b63154bac897d451114e12 76 Pfam PF06150 ChaB 9 75 3.7E-28 T 11-11-2016 IPR009317 ChaB AUP74_RS08315 8f6593abe8cdb1a22776f5542ec01e44 237 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 27 184 3.0E-28 T 11-11-2016 IPR003709 Peptidase M15B GO:0006508|GO:0008233 AUP74_RS08315 8f6593abe8cdb1a22776f5542ec01e44 237 SUPERFAMILY SSF55166 21 184 1.92E-16 T 11-11-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 AUP74_RS09475 aebdb1e687a27ffddc649f88c4d2de89 472 Pfam PF12801 4Fe-4S binding domain 92 129 7.3E-6 T 11-11-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AUP74_RS09475 aebdb1e687a27ffddc649f88c4d2de89 472 Gene3D G3DSA:3.30.70.20 279 325 6.5E-8 T 11-11-2016 AUP74_RS09475 aebdb1e687a27ffddc649f88c4d2de89 472 Pfam PF11614 IG-like fold at C-terminal of FixG, putative oxidoreductase 354 470 1.3E-26 T 11-11-2016 IPR032879 FixG, C-terminal immunoglobulin-like domain AUP74_RS09475 aebdb1e687a27ffddc649f88c4d2de89 472 Gene3D G3DSA:2.60.40.10 353 470 1.0E-28 T 11-11-2016 IPR013783 Immunoglobulin-like fold AUP74_RS09475 aebdb1e687a27ffddc649f88c4d2de89 472 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 269 280 - T 11-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AUP74_RS09475 aebdb1e687a27ffddc649f88c4d2de89 472 Pfam PF13746 4Fe-4S dicluster domain 216 322 2.2E-44 T 11-11-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AUP74_RS09475 aebdb1e687a27ffddc649f88c4d2de89 472 Gene3D G3DSA:1.10.1060.10 220 278 1.4E-7 T 11-11-2016 AUP74_RS09475 aebdb1e687a27ffddc649f88c4d2de89 472 TIGRFAM TIGR02745 ccoG_rdxA_fixG: cytochrome c oxidase accessory protein CcoG 38 469 3.4E-159 T 11-11-2016 IPR014116 Cytochrome c oxidase cbb3 type, accessory protein FixG GO:0016021 AUP74_RS09475 aebdb1e687a27ffddc649f88c4d2de89 472 SUPERFAMILY SSF54862 102 130 3.49E-28 T 11-11-2016 AUP74_RS09475 aebdb1e687a27ffddc649f88c4d2de89 472 SUPERFAMILY SSF54862 172 347 3.49E-28 T 11-11-2016 AUP74_RS04315 d52d841d7dc4d1ac35e231a7516e7e4e 431 Pfam PF00999 Sodium/hydrogen exchanger family 77 414 4.2E-56 T 11-11-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 AUP74_RS01755 6964258db4eb69b82de44ba358e0339c 235 SUPERFAMILY SSF56925 37 235 1.94E-19 T 11-11-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AUP74_RS01755 6964258db4eb69b82de44ba358e0339c 235 Pfam PF13505 Outer membrane protein beta-barrel domain 7 235 5.1E-14 T 11-11-2016 IPR027385 Outer membrane protein beta-barrel AUP74_RS01755 6964258db4eb69b82de44ba358e0339c 235 Gene3D G3DSA:2.40.160.20 12 235 1.1E-24 T 11-11-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AUP74_RS00095 67cb89ed0e0e382f77ecab798cfab212 95 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 3 95 6.6E-29 T 11-11-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 AUP74_RS00095 67cb89ed0e0e382f77ecab798cfab212 95 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 19 90 1.0E-17 T 11-11-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 AUP74_RS00095 67cb89ed0e0e382f77ecab798cfab212 95 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 95 22.132 T 11-11-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 AUP74_RS00095 67cb89ed0e0e382f77ecab798cfab212 95 SUPERFAMILY SSF141000 3 93 3.14E-28 T 11-11-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 AUP74_RS16770 dbc588020dc9130425ba9b27338abdf1 84 Hamap MF_00910 Cell division protein FtsL [ftsL]. 1 81 14.727 T 11-11-2016 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 AUP74_RS16770 dbc588020dc9130425ba9b27338abdf1 84 Pfam PF04999 Cell division protein FtsL 4 81 4.5E-24 T 11-11-2016 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 AUP74_RS16770 dbc588020dc9130425ba9b27338abdf1 84 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 5 81 8.8E-20 T 11-11-2016 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 AUP74_RS00875 ef526f4d46ff24d974642b39b9aadd87 352 SUPERFAMILY SSF142754 36 347 9.55E-111 T 11-11-2016 AUP74_RS00875 ef526f4d46ff24d974642b39b9aadd87 352 Hamap MF_00567 Quinolinate synthase A [nadA]. 1 349 66.222 T 11-11-2016 IPR023513 Quinolinate synthase A, type 1 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 AUP74_RS00875 ef526f4d46ff24d974642b39b9aadd87 352 Pfam PF02445 Quinolinate synthetase A protein 40 346 2.1E-104 T 11-11-2016 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 AUP74_RS00875 ef526f4d46ff24d974642b39b9aadd87 352 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 37 347 3.6E-112 T 11-11-2016 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 AUP74_RS14515 232868666528cb87c69cf28573116cec 200 SUPERFAMILY SSF52499 11 194 2.35E-47 T 11-11-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 AUP74_RS14515 232868666528cb87c69cf28573116cec 200 Pfam PF00857 Isochorismatase family 15 188 1.4E-37 T 11-11-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 AUP74_RS14515 232868666528cb87c69cf28573116cec 200 Gene3D G3DSA:3.40.50.850 12 194 8.4E-47 T 11-11-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 AUP74_RS10535 c93f727955c625449228b9c97060b634 184 Pfam PF04315 Elongation factor P hydroxylase 14 175 1.4E-62 T 11-11-2016 IPR007411 Elongation factor P hydroxylase AUP74_RS08740 4f4734b13584ffeea704b8a97191fdf0 205 SUPERFAMILY SSF52540 2 204 4.93E-34 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS08740 4f4734b13584ffeea704b8a97191fdf0 205 Gene3D G3DSA:3.40.50.300 1 204 8.2E-40 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS08740 4f4734b13584ffeea704b8a97191fdf0 205 Pfam PF00685 Sulfotransferase domain 13 120 4.5E-16 T 11-11-2016 IPR000863 Sulfotransferase domain GO:0008146 AUP74_RS08890 27caa843cab343359ee0d05f09d5f264 753 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 517 719 2.1E-42 T 11-11-2016 IPR005702 Exopolysaccharide synthesis protein GO:0045226 AUP74_RS08890 27caa843cab343359ee0d05f09d5f264 753 SUPERFAMILY SSF52540 535 711 1.25E-33 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS08890 27caa843cab343359ee0d05f09d5f264 753 Pfam PF13807 G-rich domain on putative tyrosine kinase 395 465 8.8E-13 T 11-11-2016 IPR032807 Tyrosine kinase, G-rich domain AUP74_RS08890 27caa843cab343359ee0d05f09d5f264 753 Gene3D G3DSA:3.40.50.300 532 710 1.4E-29 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS08890 27caa843cab343359ee0d05f09d5f264 753 Pfam PF02706 Chain length determinant protein 18 196 2.6E-19 T 11-11-2016 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 AUP74_RS08890 27caa843cab343359ee0d05f09d5f264 753 Pfam PF13614 AAA domain 536 696 4.9E-12 T 11-11-2016 IPR025669 AAA domain AUP74_RS07455 f1dc14e97996e62be7254b9f8bc91deb 432 SUPERFAMILY SSF56281 37 310 9.04E-35 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS07455 f1dc14e97996e62be7254b9f8bc91deb 432 Pfam PF00753 Metallo-beta-lactamase superfamily 53 109 1.1E-9 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS07455 f1dc14e97996e62be7254b9f8bc91deb 432 Gene3D G3DSA:3.60.15.10 37 321 9.1E-33 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS02480 b8543e6c6ef1248c4f4860d478b8a84a 224 SUPERFAMILY SSF100950 1 150 2.05E-42 T 11-11-2016 AUP74_RS02480 b8543e6c6ef1248c4f4860d478b8a84a 224 Gene3D G3DSA:3.30.70.260 141 200 2.8E-29 T 11-11-2016 AUP74_RS02480 b8543e6c6ef1248c4f4860d478b8a84a 224 Gene3D G3DSA:3.40.50.1360 1 140 8.9E-55 T 11-11-2016 AUP74_RS02480 b8543e6c6ef1248c4f4860d478b8a84a 224 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 7 219 1.9E-63 T 11-11-2016 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 AUP74_RS02480 b8543e6c6ef1248c4f4860d478b8a84a 224 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 3 221 32.721 T 11-11-2016 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 AUP74_RS02480 b8543e6c6ef1248c4f4860d478b8a84a 224 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 53 217 7.0E-58 T 11-11-2016 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 AUP74_RS02480 b8543e6c6ef1248c4f4860d478b8a84a 224 SUPERFAMILY SSF75445 131 202 2.88E-23 T 11-11-2016 AUP74_RS03260 82402a957f8f9f3cba4d1c8c7b408eac 370 Gene3D G3DSA:1.10.340.30 21 122 4.6E-45 T 11-11-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AUP74_RS03260 82402a957f8f9f3cba4d1c8c7b408eac 370 Gene3D G3DSA:3.90.79.10 229 358 1.5E-21 T 11-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 AUP74_RS03260 82402a957f8f9f3cba4d1c8c7b408eac 370 SUPERFAMILY SSF55811 220 354 3.52E-24 T 11-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 AUP74_RS03260 82402a957f8f9f3cba4d1c8c7b408eac 370 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 5 268 5.5E-116 T 11-11-2016 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 AUP74_RS03260 82402a957f8f9f3cba4d1c8c7b408eac 370 SMART SM00525 191 211 6.4E-5 T 11-11-2016 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 AUP74_RS03260 82402a957f8f9f3cba4d1c8c7b408eac 370 Pfam PF14815 NUDIX domain 234 352 5.6E-22 T 11-11-2016 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 AUP74_RS03260 82402a957f8f9f3cba4d1c8c7b408eac 370 SMART SM00478 39 190 6.7E-50 T 11-11-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AUP74_RS03260 82402a957f8f9f3cba4d1c8c7b408eac 370 Gene3D G3DSA:1.10.1670.10 123 224 3.1E-40 T 11-11-2016 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 AUP74_RS03260 82402a957f8f9f3cba4d1c8c7b408eac 370 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 192 208 - T 11-11-2016 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 AUP74_RS03260 82402a957f8f9f3cba4d1c8c7b408eac 370 SUPERFAMILY SSF48150 3 225 3.45E-79 T 11-11-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AUP74_RS03260 82402a957f8f9f3cba4d1c8c7b408eac 370 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 35 168 9.4E-20 T 11-11-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AUP74_RS03260 82402a957f8f9f3cba4d1c8c7b408eac 370 ProSitePatterns PS01155 Endonuclease III family signature. 102 131 - T 11-11-2016 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 AUP74_RS03260 82402a957f8f9f3cba4d1c8c7b408eac 370 Pfam PF00633 Helix-hairpin-helix motif 99 128 2.0E-6 T 11-11-2016 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 AUP74_RS03425 a39a1a75b1e8c7622072b5be4a735449 143 Gene3D G3DSA:1.10.1660.10 3 57 5.8E-23 T 11-11-2016 AUP74_RS03425 a39a1a75b1e8c7622072b5be4a735449 143 Gene3D G3DSA:1.10.1660.10 58 128 5.5E-11 T 11-11-2016 AUP74_RS03425 a39a1a75b1e8c7622072b5be4a735449 143 SUPERFAMILY SSF46955 4 118 6.23E-27 T 11-11-2016 IPR009061 Putative DNA-binding domain AUP74_RS03425 a39a1a75b1e8c7622072b5be4a735449 143 SMART SM00422 3 72 6.8E-23 T 11-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AUP74_RS03425 a39a1a75b1e8c7622072b5be4a735449 143 Pfam PF13411 MerR HTH family regulatory protein 4 70 1.2E-16 T 11-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AUP74_RS03425 a39a1a75b1e8c7622072b5be4a735449 143 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 7.3E-11 T 11-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AUP74_RS03425 a39a1a75b1e8c7622072b5be4a735449 143 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 7.3E-11 T 11-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AUP74_RS03425 a39a1a75b1e8c7622072b5be4a735449 143 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 7.3E-11 T 11-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AUP74_RS01530 aff5815b2c04b69fe11d4d8ddaf36047 159 PIRSF PIRSF006162 4 159 3.0E-49 T 11-11-2016 IPR026037 Phosphatidylglycerophosphatase A KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668 AUP74_RS01530 aff5815b2c04b69fe11d4d8ddaf36047 159 Pfam PF04608 Phosphatidylglycerophosphatase A 16 153 4.2E-53 T 11-11-2016 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 AUP74_RS01530 aff5815b2c04b69fe11d4d8ddaf36047 159 SUPERFAMILY SSF101307 10 153 1.01E-44 T 11-11-2016 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 AUP74_RS00465 9afa3e29a8ea9a3d7ee33d01fdf1e9c4 218 Gene3D G3DSA:3.40.1050.10 4 214 3.9E-75 T 11-11-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 AUP74_RS00465 9afa3e29a8ea9a3d7ee33d01fdf1e9c4 218 Pfam PF00484 Carbonic anhydrase 37 187 4.1E-52 T 11-11-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 AUP74_RS00465 9afa3e29a8ea9a3d7ee33d01fdf1e9c4 218 SUPERFAMILY SSF53056 3 213 3.01E-74 T 11-11-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 AUP74_RS00465 9afa3e29a8ea9a3d7ee33d01fdf1e9c4 218 SMART SM00947 30 192 1.4E-67 T 11-11-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 AUP74_RS00465 9afa3e29a8ea9a3d7ee33d01fdf1e9c4 218 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 82 102 - T 11-11-2016 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 AUP74_RS00465 9afa3e29a8ea9a3d7ee33d01fdf1e9c4 218 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 42 49 - T 11-11-2016 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 AUP74_RS13730 4e1053d34951bd4dd248fec9467d90d1 266 Pfam PF07103 Protein of unknown function (DUF1365) 14 254 1.2E-70 T 11-11-2016 IPR010775 Protein of unknown function DUF1365 AUP74_RS09930 8639343ac18781af2daea5ae788ef5f7 515 Pfam PF00082 Subtilase family 407 484 5.5E-14 T 11-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AUP74_RS09930 8639343ac18781af2daea5ae788ef5f7 515 Pfam PF00082 Subtilase family 116 304 3.9E-26 T 11-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AUP74_RS09930 8639343ac18781af2daea5ae788ef5f7 515 Gene3D G3DSA:3.50.30.30 298 422 2.9E-31 T 11-11-2016 AUP74_RS09930 8639343ac18781af2daea5ae788ef5f7 515 PRINTS PR00723 Subtilisin serine protease family (S8) signature 114 133 2.4E-19 T 11-11-2016 IPR015500 Peptidase S8, subtilisin-related AUP74_RS09930 8639343ac18781af2daea5ae788ef5f7 515 PRINTS PR00723 Subtilisin serine protease family (S8) signature 433 449 2.4E-19 T 11-11-2016 IPR015500 Peptidase S8, subtilisin-related AUP74_RS09930 8639343ac18781af2daea5ae788ef5f7 515 PRINTS PR00723 Subtilisin serine protease family (S8) signature 151 164 2.4E-19 T 11-11-2016 IPR015500 Peptidase S8, subtilisin-related AUP74_RS09930 8639343ac18781af2daea5ae788ef5f7 515 Gene3D G3DSA:3.30.70.80 29 78 7.7E-7 T 11-11-2016 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 AUP74_RS09930 8639343ac18781af2daea5ae788ef5f7 515 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 434 444 - T 11-11-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site AUP74_RS09930 8639343ac18781af2daea5ae788ef5f7 515 SUPERFAMILY SSF52743 99 495 1.85E-77 T 11-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AUP74_RS09930 8639343ac18781af2daea5ae788ef5f7 515 Pfam PF02225 PA domain 335 411 5.3E-12 T 11-11-2016 IPR003137 PA domain AUP74_RS09930 8639343ac18781af2daea5ae788ef5f7 515 Gene3D G3DSA:3.40.50.200 423 495 5.2E-80 T 11-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AUP74_RS09930 8639343ac18781af2daea5ae788ef5f7 515 Gene3D G3DSA:3.40.50.200 79 297 5.2E-80 T 11-11-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AUP74_RS09930 8639343ac18781af2daea5ae788ef5f7 515 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 155 165 - T 11-11-2016 IPR022398 Peptidase S8, subtilisin, His-active site AUP74_RS01210 42a4fd1397af6c2d8b7786ebd8c250f4 334 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 7 324 8.1E-84 T 11-11-2016 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 AUP74_RS01210 42a4fd1397af6c2d8b7786ebd8c250f4 334 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 9 329 7.7E-37 T 11-11-2016 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 AUP74_RS05720 9a266d3b2c9f516127308e54b407fd0c 885 Pfam PF00905 Penicillin binding protein transpeptidase domain 472 799 1.6E-29 T 11-11-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 AUP74_RS05720 9a266d3b2c9f516127308e54b407fd0c 885 Gene3D G3DSA:3.40.710.10 716 852 5.3E-134 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS05720 9a266d3b2c9f516127308e54b407fd0c 885 Gene3D G3DSA:3.40.710.10 237 318 5.3E-134 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS05720 9a266d3b2c9f516127308e54b407fd0c 885 Gene3D G3DSA:3.40.710.10 465 658 5.3E-134 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS05720 9a266d3b2c9f516127308e54b407fd0c 885 Pfam PF00912 Transglycosylase 61 234 4.6E-59 T 11-11-2016 IPR001264 Glycosyl transferase, family 51 AUP74_RS05720 9a266d3b2c9f516127308e54b407fd0c 885 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 70 809 1.2E-177 T 11-11-2016 AUP74_RS05720 9a266d3b2c9f516127308e54b407fd0c 885 SUPERFAMILY SSF53955 48 263 1.91E-72 T 11-11-2016 IPR023346 Lysozyme-like domain AUP74_RS05720 9a266d3b2c9f516127308e54b407fd0c 885 SUPERFAMILY SSF56601 715 837 3.65E-126 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS05720 9a266d3b2c9f516127308e54b407fd0c 885 SUPERFAMILY SSF56601 467 655 3.65E-126 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS05720 9a266d3b2c9f516127308e54b407fd0c 885 SUPERFAMILY SSF56601 216 238 3.65E-126 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS05720 9a266d3b2c9f516127308e54b407fd0c 885 SUPERFAMILY SSF56601 267 318 3.65E-126 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS05720 9a266d3b2c9f516127308e54b407fd0c 885 Gene3D G3DSA:2.40.50.140 350 417 2.4E-13 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS05720 9a266d3b2c9f516127308e54b407fd0c 885 Pfam PF17092 Penicillin-binding protein OB-like domain 321 470 3.0E-20 T 11-11-2016 IPR031376 Penicillin-binding protein, OB-like domain AUP74_RS05720 9a266d3b2c9f516127308e54b407fd0c 885 Gene3D G3DSA:1.10.3810.10 61 236 2.8E-68 T 11-11-2016 AUP74_RS12535 9a424a18ea2d42f43cc0b1da46b263ed 285 SUPERFAMILY SSF50182 90 163 1.7E-10 T 11-11-2016 IPR010920 LSM domain AUP74_RS12535 9a424a18ea2d42f43cc0b1da46b263ed 285 Gene3D G3DSA:2.30.30.60 106 163 9.1E-13 T 11-11-2016 AUP74_RS12535 9a424a18ea2d42f43cc0b1da46b263ed 285 Pfam PF00924 Mechanosensitive ion channel 56 216 1.5E-15 T 11-11-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 AUP74_RS09395 1f8d05851ca867959f378bdf34c172ce 645 SUPERFAMILY SSF54001 224 371 6.73E-11 T 11-11-2016 AUP74_RS09395 1f8d05851ca867959f378bdf34c172ce 645 Pfam PF12969 Domain of Unknown Function with PDB structure (DUF3857) 48 191 3.5E-24 T 11-11-2016 IPR024618 Domain of unknown function DUF3857 AUP74_RS11005 f4bf9c1675e9b2bf4307e336c115bd45 105 SUPERFAMILY SSF55718 23 102 5.42E-8 T 11-11-2016 IPR003033 SCP2 sterol-binding domain AUP74_RS11005 f4bf9c1675e9b2bf4307e336c115bd45 105 Gene3D G3DSA:3.30.1050.10 51 103 3.2E-6 T 11-11-2016 IPR003033 SCP2 sterol-binding domain AUP74_RS07090 7171d94155bcc309858659e988687a8f 146 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 8 139 6.9E-19 T 11-11-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 AUP74_RS07090 7171d94155bcc309858659e988687a8f 146 SUPERFAMILY SSF54534 8 142 4.52E-38 T 11-11-2016 AUP74_RS07090 7171d94155bcc309858659e988687a8f 146 Gene3D G3DSA:3.10.50.40 7 83 3.3E-22 T 11-11-2016 AUP74_RS07090 7171d94155bcc309858659e988687a8f 146 Gene3D G3DSA:3.10.50.40 129 142 3.3E-22 T 11-11-2016 AUP74_RS14145 c5703679fc542c2df102e88b65914945 508 Pfam PF03553 Na+/H+ antiporter family 166 474 9.4E-48 T 11-11-2016 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 AUP74_RS14145 c5703679fc542c2df102e88b65914945 508 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 35 479 2.2E-120 T 11-11-2016 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 AUP74_RS03610 1fcf24efa05504c13a85765b77b8df95 444 SUPERFAMILY SSF53187 242 402 5.95E-22 T 11-11-2016 AUP74_RS03610 1fcf24efa05504c13a85765b77b8df95 444 SUPERFAMILY SSF53187 106 177 5.95E-22 T 11-11-2016 AUP74_RS03610 1fcf24efa05504c13a85765b77b8df95 444 Gene3D G3DSA:3.40.630.10 96 181 1.1E-22 T 11-11-2016 AUP74_RS03610 1fcf24efa05504c13a85765b77b8df95 444 Gene3D G3DSA:3.40.630.10 242 352 1.1E-22 T 11-11-2016 AUP74_RS03610 1fcf24efa05504c13a85765b77b8df95 444 Pfam PF10994 Protein of unknown function (DUF2817) 60 409 8.8E-66 T 11-11-2016 IPR021259 Protein of unknown function DUF2817 AUP74_RS00670 7e655a66a07e04dcc51d9b0a1b37eb6a 607 SUPERFAMILY SSF48452 194 382 5.55E-12 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS00670 7e655a66a07e04dcc51d9b0a1b37eb6a 607 Pfam PF13759 Putative 2OG-Fe(II) oxygenase 504 601 5.0E-17 T 11-11-2016 IPR012668 Conserved hypothetical protein CHP02466 AUP74_RS00670 7e655a66a07e04dcc51d9b0a1b37eb6a 607 Gene3D G3DSA:1.25.40.10 289 394 1.3E-7 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS00670 7e655a66a07e04dcc51d9b0a1b37eb6a 607 Gene3D G3DSA:1.25.40.10 16 262 1.6E-51 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS00670 7e655a66a07e04dcc51d9b0a1b37eb6a 607 SUPERFAMILY SSF48452 17 257 5.55E-32 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS00670 7e655a66a07e04dcc51d9b0a1b37eb6a 607 SMART SM00028 177 210 0.95 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS00670 7e655a66a07e04dcc51d9b0a1b37eb6a 607 SMART SM00028 41 74 47.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS00670 7e655a66a07e04dcc51d9b0a1b37eb6a 607 SMART SM00028 211 244 1.4 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS00670 7e655a66a07e04dcc51d9b0a1b37eb6a 607 SMART SM00028 75 108 0.024 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS00670 7e655a66a07e04dcc51d9b0a1b37eb6a 607 SMART SM00028 109 142 14.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS00670 7e655a66a07e04dcc51d9b0a1b37eb6a 607 SMART SM00028 312 345 48.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS00670 7e655a66a07e04dcc51d9b0a1b37eb6a 607 SMART SM00028 143 176 1.4E-6 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS00670 7e655a66a07e04dcc51d9b0a1b37eb6a 607 Pfam PF13432 Tetratricopeptide repeat 149 211 9.4E-8 T 11-11-2016 AUP74_RS00670 7e655a66a07e04dcc51d9b0a1b37eb6a 607 Pfam PF13432 Tetratricopeptide repeat 215 269 5.4E-5 T 11-11-2016 AUP74_RS00670 7e655a66a07e04dcc51d9b0a1b37eb6a 607 Gene3D G3DSA:2.60.120.620 413 604 2.7E-34 T 11-11-2016 AUP74_RS06765 2871474f6e972b189688df02000b4ccf 143 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 74 3.0E-14 T 11-11-2016 AUP74_RS06765 2871474f6e972b189688df02000b4ccf 143 SUPERFAMILY SSF54747 3 72 1.3E-30 T 11-11-2016 IPR020784 Ribosomal protein L11, N-terminal AUP74_RS06765 2871474f6e972b189688df02000b4ccf 143 SUPERFAMILY SSF46906 68 141 9.16E-25 T 11-11-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 AUP74_RS06765 2871474f6e972b189688df02000b4ccf 143 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 8.3E-65 T 11-11-2016 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06765 2871474f6e972b189688df02000b4ccf 143 Gene3D G3DSA:1.10.10.250 73 141 3.7E-29 T 11-11-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 AUP74_RS06765 2871474f6e972b189688df02000b4ccf 143 Gene3D G3DSA:3.30.1550.10 2 72 8.5E-39 T 11-11-2016 IPR020784 Ribosomal protein L11, N-terminal AUP74_RS06765 2871474f6e972b189688df02000b4ccf 143 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 140 3.0E-22 T 11-11-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 AUP74_RS06765 2871474f6e972b189688df02000b4ccf 143 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 142 31.041 T 11-11-2016 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 AUP74_RS06765 2871474f6e972b189688df02000b4ccf 143 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 8.9E-30 T 11-11-2016 IPR020784 Ribosomal protein L11, N-terminal AUP74_RS06765 2871474f6e972b189688df02000b4ccf 143 SMART SM00649 9 141 1.9E-82 T 11-11-2016 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 AUP74_RS09360 3c690b99aca464f741c490cc1b0c1143 543 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 84 107 - T 11-11-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 AUP74_RS09360 3c690b99aca464f741c490cc1b0c1143 543 SUPERFAMILY SSF51905 471 530 4.86E-87 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS09360 3c690b99aca464f741c490cc1b0c1143 543 SUPERFAMILY SSF51905 4 287 4.86E-87 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS09360 3c690b99aca464f741c490cc1b0c1143 543 Pfam PF00732 GMC oxidoreductase 7 294 3.0E-87 T 11-11-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 AUP74_RS09360 3c690b99aca464f741c490cc1b0c1143 543 PIRSF PIRSF000137 1 538 2.1E-152 T 11-11-2016 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 AUP74_RS09360 3c690b99aca464f741c490cc1b0c1143 543 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 253 267 - T 11-11-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 AUP74_RS09360 3c690b99aca464f741c490cc1b0c1143 543 SUPERFAMILY SSF54373 289 472 8.34E-50 T 11-11-2016 AUP74_RS09360 3c690b99aca464f741c490cc1b0c1143 543 Pfam PF05199 GMC oxidoreductase 386 522 9.9E-44 T 11-11-2016 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 AUP74_RS09360 3c690b99aca464f741c490cc1b0c1143 543 Gene3D G3DSA:3.50.50.60 6 128 1.2E-121 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS09360 3c690b99aca464f741c490cc1b0c1143 543 Gene3D G3DSA:3.50.50.60 465 530 1.2E-121 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS09360 3c690b99aca464f741c490cc1b0c1143 543 Gene3D G3DSA:3.50.50.60 189 312 1.2E-121 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS15610 7a046d2a3298f0d40349affe3fd5dafd 171 Pfam PF03938 Outer membrane protein (OmpH-like) 10 167 1.3E-18 T 11-11-2016 IPR005632 Chaperone protein Skp GO:0051082 AUP74_RS15610 7a046d2a3298f0d40349affe3fd5dafd 171 SUPERFAMILY SSF111384 23 168 1.7E-19 T 11-11-2016 IPR024930 Skp domain AUP74_RS15610 7a046d2a3298f0d40349affe3fd5dafd 171 Gene3D G3DSA:3.30.910.20 15 168 5.6E-11 T 11-11-2016 AUP74_RS15610 7a046d2a3298f0d40349affe3fd5dafd 171 SMART SM00935 12 168 3.1E-28 T 11-11-2016 IPR005632 Chaperone protein Skp GO:0051082 AUP74_RS16495 f3ca8ff9315617e5db70b1a0092557fc 144 Pfam PF01951 Archease protein family (MTH1598/TM1083) 10 144 4.6E-36 T 11-11-2016 IPR023572 Archease domain Reactome: R-HSA-6784531 AUP74_RS16495 f3ca8ff9315617e5db70b1a0092557fc 144 Gene3D G3DSA:3.55.10.10 9 144 2.6E-37 T 11-11-2016 IPR023572 Archease domain Reactome: R-HSA-6784531 AUP74_RS16495 f3ca8ff9315617e5db70b1a0092557fc 144 SUPERFAMILY SSF69819 9 144 3.53E-38 T 11-11-2016 IPR023572 Archease domain Reactome: R-HSA-6784531 AUP74_RS16495 f3ca8ff9315617e5db70b1a0092557fc 144 ProDom PD012969 UPF0211 RIKEN CDNA ENRICHED MALE FULL-LENGTH LIBRARY ZBTB8OS ADULT C43H8.1 15 143 2.0E-39 T 11-11-2016 IPR023572 Archease domain Reactome: R-HSA-6784531 AUP74_RS12145 4c61343e260023dbcca5dcd1471e1415 380 Gene3D G3DSA:3.30.565.10 250 376 4.1E-11 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS12145 4c61343e260023dbcca5dcd1471e1415 380 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 286 376 3.1E-7 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS12145 4c61343e260023dbcca5dcd1471e1415 380 Pfam PF07730 Histidine kinase 172 238 6.4E-20 T 11-11-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AUP74_RS12145 4c61343e260023dbcca5dcd1471e1415 380 SUPERFAMILY SSF55874 282 374 1.1E-16 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS12145 4c61343e260023dbcca5dcd1471e1415 380 SMART SM00387 280 377 3.1E-7 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS16925 da95c0671fe5fdf420b10366dfccbcd0 321 Pfam PF01699 Sodium/calcium exchanger protein 172 318 3.8E-29 T 11-11-2016 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 AUP74_RS16925 da95c0671fe5fdf420b10366dfccbcd0 321 Pfam PF01699 Sodium/calcium exchanger protein 8 145 6.2E-25 T 11-11-2016 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 AUP74_RS16925 da95c0671fe5fdf420b10366dfccbcd0 321 TIGRFAM TIGR00367 TIGR00367: K+-dependent Na+/Ca+ exchanger homolog 9 314 2.3E-67 T 11-11-2016 IPR004481 Sodium/potassium/calcium exchanger Reactome: R-HSA-425561 AUP74_RS00140 ac84e7c3e89293b876c4cea524a14739 454 PIRSF PIRSF006603 11 448 7.6E-62 T 11-11-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AUP74_RS00140 ac84e7c3e89293b876c4cea524a14739 454 Pfam PF01554 MatE 248 409 3.9E-26 T 11-11-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AUP74_RS00140 ac84e7c3e89293b876c4cea524a14739 454 Pfam PF01554 MatE 22 181 1.0E-30 T 11-11-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AUP74_RS00140 ac84e7c3e89293b876c4cea524a14739 454 TIGRFAM TIGR00797 matE: MATE efflux family protein 22 421 2.9E-81 T 11-11-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AUP74_RS13880 b9b3b01466b02f370318aa7bea23182b 133 Pfam PF01124 MAPEG family 5 124 2.7E-26 T 11-11-2016 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein AUP74_RS13880 b9b3b01466b02f370318aa7bea23182b 133 Gene3D G3DSA:1.20.120.550 4 131 2.0E-20 T 11-11-2016 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain AUP74_RS13880 b9b3b01466b02f370318aa7bea23182b 133 SUPERFAMILY SSF161084 2 130 1.31E-27 T 11-11-2016 AUP74_RS04185 6b0eaf5096d0503512e28ae74a374e5a 102 SUPERFAMILY SSF54909 4 68 1.91E-10 T 11-11-2016 IPR011008 Dimeric alpha-beta barrel AUP74_RS04185 6b0eaf5096d0503512e28ae74a374e5a 102 Pfam PF03992 Antibiotic biosynthesis monooxygenase 5 69 1.8E-6 T 11-11-2016 IPR007138 Antibiotic biosynthesis monooxygenase domain AUP74_RS04185 6b0eaf5096d0503512e28ae74a374e5a 102 Gene3D G3DSA:3.30.70.900 9 69 6.8E-10 T 11-11-2016 AUP74_RS04240 20d773e09dd83e997ed92c4b30014d07 506 Pfam PF11604 Copper binding periplasmic protein CusF 411 474 1.3E-9 T 11-11-2016 IPR021647 Copper binding periplasmic protein CusF AUP74_RS04240 20d773e09dd83e997ed92c4b30014d07 506 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 102 310 7.3E-68 T 11-11-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AUP74_RS04240 20d773e09dd83e997ed92c4b30014d07 506 SUPERFAMILY SSF111369 124 315 1.44E-12 T 11-11-2016 AUP74_RS04240 20d773e09dd83e997ed92c4b30014d07 506 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 200 389 6.3E-32 T 11-11-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 AUP74_RS04240 20d773e09dd83e997ed92c4b30014d07 506 Gene3D G3DSA:2.40.50.100 124 153 3.8E-8 T 11-11-2016 AUP74_RS04240 20d773e09dd83e997ed92c4b30014d07 506 Gene3D G3DSA:2.40.50.100 204 235 3.8E-8 T 11-11-2016 AUP74_RS02575 fdfcafc15c244009dbf0b4c81f0382ee 401 PIRSF PIRSF006060 1 400 2.3E-61 T 11-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 AUP74_RS02575 fdfcafc15c244009dbf0b4c81f0382ee 401 Pfam PF00324 Amino acid permease 18 398 1.0E-29 T 11-11-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 AUP74_RS14400 9a3e2e53f648a16520bda6bb16d7bdda 103 Gene3D G3DSA:3.30.70.900 5 102 2.6E-4 T 11-11-2016 AUP74_RS14400 9a3e2e53f648a16520bda6bb16d7bdda 103 Pfam PF11639 REDY-like protein HapK 4 93 4.7E-10 T 11-11-2016 IPR021667 REDY-like protein HapK AUP74_RS14400 9a3e2e53f648a16520bda6bb16d7bdda 103 SUPERFAMILY SSF54909 4 99 3.4E-7 T 11-11-2016 IPR011008 Dimeric alpha-beta barrel AUP74_RS05525 37ed36c6eec35ab5bcaccab37a47fe2c 196 SUPERFAMILY SSF53335 4 170 3.01E-30 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS05525 37ed36c6eec35ab5bcaccab37a47fe2c 196 TIGRFAM TIGR02081 metW: methionine biosynthesis protein MetW 2 194 1.7E-80 T 11-11-2016 IPR010743 Methionine biosynthesis MetW AUP74_RS05525 37ed36c6eec35ab5bcaccab37a47fe2c 196 Gene3D G3DSA:3.40.50.150 7 169 4.3E-26 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS05525 37ed36c6eec35ab5bcaccab37a47fe2c 196 Pfam PF07021 Methionine biosynthesis protein MetW 2 194 9.5E-81 T 11-11-2016 IPR010743 Methionine biosynthesis MetW AUP74_RS08250 27392d019a00acc6c1df5d5419a158d8 271 Gene3D G3DSA:3.20.20.60 10 270 6.4E-111 T 11-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AUP74_RS08250 27392d019a00acc6c1df5d5419a158d8 271 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 11 270 4.0E-106 T 11-11-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 AUP74_RS08250 27392d019a00acc6c1df5d5419a158d8 271 Pfam PF02548 Ketopantoate hydroxymethyltransferase 12 265 5.5E-108 T 11-11-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 AUP74_RS08250 27392d019a00acc6c1df5d5419a158d8 271 SUPERFAMILY SSF51621 12 270 2.16E-103 T 11-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AUP74_RS08250 27392d019a00acc6c1df5d5419a158d8 271 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 12 270 41.939 T 11-11-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 AUP74_RS08250 27392d019a00acc6c1df5d5419a158d8 271 PIRSF PIRSF000388 3 271 2.7E-102 T 11-11-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 AUP74_RS09020 1c3007e22ca4a0d0f7b1a28c780d1a5b 491 Gene3D G3DSA:3.90.226.10 227 263 6.0E-19 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS09020 1c3007e22ca4a0d0f7b1a28c780d1a5b 491 Gene3D G3DSA:3.90.226.10 33 139 6.0E-19 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS09020 1c3007e22ca4a0d0f7b1a28c780d1a5b 491 Pfam PF01957 NfeD-like C-terminal, partner-binding 354 490 8.1E-30 T 11-11-2016 IPR002810 NfeD-like, C-terminal domain AUP74_RS09020 1c3007e22ca4a0d0f7b1a28c780d1a5b 491 Gene3D G3DSA:2.40.50.140 437 491 5.8E-11 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS09020 1c3007e22ca4a0d0f7b1a28c780d1a5b 491 SUPERFAMILY SSF52096 18 145 3.34E-25 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS09020 1c3007e22ca4a0d0f7b1a28c780d1a5b 491 SUPERFAMILY SSF52096 193 252 3.34E-25 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS09020 1c3007e22ca4a0d0f7b1a28c780d1a5b 491 SUPERFAMILY SSF141322 428 489 5.62E-11 T 11-11-2016 AUP74_RS15970 03fa9070c615f6e98b36dfd680bd768d 456 Pfam PF00375 Sodium:dicarboxylate symporter family 30 441 9.5E-96 T 11-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AUP74_RS15970 03fa9070c615f6e98b36dfd680bd768d 456 SUPERFAMILY SSF118215 30 441 2.09E-88 T 11-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AUP74_RS15970 03fa9070c615f6e98b36dfd680bd768d 456 Gene3D G3DSA:1.10.3860.10 25 445 5.3E-93 T 11-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AUP74_RS15970 03fa9070c615f6e98b36dfd680bd768d 456 PRINTS PR00173 Glutamate-aspartate symporter signature 27 47 2.8E-23 T 11-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AUP74_RS15970 03fa9070c615f6e98b36dfd680bd768d 456 PRINTS PR00173 Glutamate-aspartate symporter signature 368 387 2.8E-23 T 11-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AUP74_RS15970 03fa9070c615f6e98b36dfd680bd768d 456 PRINTS PR00173 Glutamate-aspartate symporter signature 395 415 2.8E-23 T 11-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AUP74_RS15970 03fa9070c615f6e98b36dfd680bd768d 456 PRINTS PR00173 Glutamate-aspartate symporter signature 104 129 2.8E-23 T 11-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AUP74_RS15970 03fa9070c615f6e98b36dfd680bd768d 456 PRINTS PR00173 Glutamate-aspartate symporter signature 74 94 2.8E-23 T 11-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AUP74_RS15970 03fa9070c615f6e98b36dfd680bd768d 456 PRINTS PR00173 Glutamate-aspartate symporter signature 231 250 2.8E-23 T 11-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AUP74_RS00425 0a0cb66d83a01ce9c4901abece81008f 333 SUPERFAMILY SSF52540 1 209 1.3E-51 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS00425 0a0cb66d83a01ce9c4901abece81008f 333 Gene3D G3DSA:3.40.50.300 1 139 2.2E-54 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS00425 0a0cb66d83a01ce9c4901abece81008f 333 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 16 327 6.6E-92 T 11-11-2016 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 AUP74_RS00425 0a0cb66d83a01ce9c4901abece81008f 333 Gene3D G3DSA:1.10.8.60 143 221 3.7E-32 T 11-11-2016 AUP74_RS00425 0a0cb66d83a01ce9c4901abece81008f 333 Pfam PF06144 DNA polymerase III, delta subunit 20 189 9.3E-34 T 11-11-2016 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 AUP74_RS00425 0a0cb66d83a01ce9c4901abece81008f 333 Gene3D G3DSA:1.20.272.20 222 331 8.9E-31 T 11-11-2016 AUP74_RS00425 0a0cb66d83a01ce9c4901abece81008f 333 SUPERFAMILY SSF48019 211 329 2.38E-23 T 11-11-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 AUP74_RS01005 968e74190ab0788709d88cd1141dca91 311 Pfam PF01738 Dienelactone hydrolase family 33 139 1.9E-6 T 11-11-2016 IPR002925 Dienelactone hydrolase GO:0016787 AUP74_RS01005 968e74190ab0788709d88cd1141dca91 311 SUPERFAMILY SSF53474 179 311 5.9E-42 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS01005 968e74190ab0788709d88cd1141dca91 311 SUPERFAMILY SSF53474 3 144 5.9E-42 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS01005 968e74190ab0788709d88cd1141dca91 311 Gene3D G3DSA:3.40.50.1820 8 311 1.1E-56 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS11420 b0afd0bbb431ac15590aa7d2ef53354c 182 SUPERFAMILY SSF55811 53 173 9.34E-25 T 11-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 AUP74_RS11420 b0afd0bbb431ac15590aa7d2ef53354c 182 PRINTS PR00502 NUDIX hydrolase family signature 92 107 1.4E-6 T 11-11-2016 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AUP74_RS11420 b0afd0bbb431ac15590aa7d2ef53354c 182 PRINTS PR00502 NUDIX hydrolase family signature 78 92 1.4E-6 T 11-11-2016 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AUP74_RS11420 b0afd0bbb431ac15590aa7d2ef53354c 182 Gene3D G3DSA:3.90.79.10 54 170 6.7E-25 T 11-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 AUP74_RS11420 b0afd0bbb431ac15590aa7d2ef53354c 182 Pfam PF00293 NUDIX domain 55 169 4.5E-16 T 11-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 AUP74_RS12870 94aeb8be464ff54946c012961de0cfc4 141 Pfam PF13673 Acetyltransferase (GNAT) domain 41 139 2.8E-23 T 11-11-2016 IPR000182 GNAT domain GO:0008080 AUP74_RS12870 94aeb8be464ff54946c012961de0cfc4 141 Gene3D G3DSA:3.40.630.30 13 139 1.3E-36 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS12870 94aeb8be464ff54946c012961de0cfc4 141 SUPERFAMILY SSF55729 4 141 1.59E-38 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS13815 c3e6692912df41681163d15b1e9848eb 396 PRINTS PR00799 Aspartate aminotransferase signature 273 298 4.1E-35 T 11-11-2016 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 AUP74_RS13815 c3e6692912df41681163d15b1e9848eb 396 PRINTS PR00799 Aspartate aminotransferase signature 206 218 4.1E-35 T 11-11-2016 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 AUP74_RS13815 c3e6692912df41681163d15b1e9848eb 396 PRINTS PR00799 Aspartate aminotransferase signature 175 194 4.1E-35 T 11-11-2016 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 AUP74_RS13815 c3e6692912df41681163d15b1e9848eb 396 PRINTS PR00799 Aspartate aminotransferase signature 341 359 4.1E-35 T 11-11-2016 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 AUP74_RS13815 c3e6692912df41681163d15b1e9848eb 396 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 243 256 - T 11-11-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 AUP74_RS13815 c3e6692912df41681163d15b1e9848eb 396 Gene3D G3DSA:3.40.640.10 45 315 8.3E-96 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AUP74_RS13815 c3e6692912df41681163d15b1e9848eb 396 Pfam PF00155 Aminotransferase class I and II 27 392 1.2E-78 T 11-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AUP74_RS13815 c3e6692912df41681163d15b1e9848eb 396 SUPERFAMILY SSF53383 1 395 2.23E-110 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase AUP74_RS09690 946d63a6b076e1497f5a3ad7de5070d9 422 PIRSF PIRSF006060 1 421 1.5E-50 T 11-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 AUP74_RS09690 946d63a6b076e1497f5a3ad7de5070d9 422 Pfam PF13520 Amino acid permease 12 381 9.7E-38 T 11-11-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 AUP74_RS03985 06497bd07ccac35f6898def0c8a7b4ed 51 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 15.474 T 11-11-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS03985 06497bd07ccac35f6898def0c8a7b4ed 51 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 11-11-2016 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS03985 06497bd07ccac35f6898def0c8a7b4ed 51 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 51 1.9E-25 T 11-11-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS03985 06497bd07ccac35f6898def0c8a7b4ed 51 Pfam PF00471 Ribosomal protein L33 4 49 1.4E-18 T 11-11-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS03985 06497bd07ccac35f6898def0c8a7b4ed 51 SUPERFAMILY SSF57829 1 49 3.85E-19 T 11-11-2016 IPR011332 Zinc-binding ribosomal protein GO:0006412 AUP74_RS16875 da4c72ab49928fbe43889342d2ee6fe9 369 Gene3D G3DSA:3.40.50.300 5 177 7.5E-23 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS16875 da4c72ab49928fbe43889342d2ee6fe9 369 Pfam PF03969 AFG1-like ATPase 6 365 9.9E-150 T 11-11-2016 IPR005654 ATPase, AFG1-like GO:0005524 AUP74_RS16875 da4c72ab49928fbe43889342d2ee6fe9 369 SUPERFAMILY SSF52540 60 201 3.32E-15 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS16875 da4c72ab49928fbe43889342d2ee6fe9 369 Hamap MF_01919 Cell division protein ZapE [zapE]. 5 369 52.884 T 11-11-2016 IPR030870 Cell division protein ZapE GO:0016887|GO:0051301 AUP74_RS10790 5983ad4d19eb187ffb12b2dccc586756 143 Gene3D G3DSA:1.10.287.70 55 141 7.1E-12 T 11-11-2016 AUP74_RS10790 5983ad4d19eb187ffb12b2dccc586756 143 Pfam PF07885 Ion channel 65 135 4.5E-13 T 11-11-2016 IPR013099 Potassium channel domain AUP74_RS10790 5983ad4d19eb187ffb12b2dccc586756 143 SUPERFAMILY SSF81324 52 135 3.4E-13 T 11-11-2016 AUP74_RS08005 859715b02ff1df5245835e1f8680b58b 368 PRINTS PR00164 ABC-2 type transport system membrane protein signature 310 329 3.7E-8 T 11-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 AUP74_RS08005 859715b02ff1df5245835e1f8680b58b 368 PRINTS PR00164 ABC-2 type transport system membrane protein signature 253 277 3.7E-8 T 11-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 AUP74_RS08005 859715b02ff1df5245835e1f8680b58b 368 PRINTS PR00164 ABC-2 type transport system membrane protein signature 290 309 3.7E-8 T 11-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 AUP74_RS08005 859715b02ff1df5245835e1f8680b58b 368 Pfam PF12698 ABC-2 family transporter protein 22 360 3.1E-48 T 11-11-2016 AUP74_RS06540 86edc3b43b440887d62235730ee5428c 158 Pfam PF04314 Protein of unknown function (DUF461) 34 134 4.0E-23 T 11-11-2016 IPR007410 DR1885-like metal-binding protein AUP74_RS06540 86edc3b43b440887d62235730ee5428c 158 SUPERFAMILY SSF110087 6 145 3.53E-31 T 11-11-2016 IPR007410 DR1885-like metal-binding protein AUP74_RS16420 3d572e49ccccc48cebc1ac9cb2dad0ef 336 Pfam PF12833 Helix-turn-helix domain 252 328 1.2E-16 T 11-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AUP74_RS16420 3d572e49ccccc48cebc1ac9cb2dad0ef 336 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 281 323 - T 11-11-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AUP74_RS16420 3d572e49ccccc48cebc1ac9cb2dad0ef 336 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 296 311 3.1E-5 T 11-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AUP74_RS16420 3d572e49ccccc48cebc1ac9cb2dad0ef 336 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 311 327 3.1E-5 T 11-11-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AUP74_RS16420 3d572e49ccccc48cebc1ac9cb2dad0ef 336 Gene3D G3DSA:1.10.10.60 280 331 7.0E-14 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS16420 3d572e49ccccc48cebc1ac9cb2dad0ef 336 SUPERFAMILY SSF46689 281 331 7.62E-12 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS16420 3d572e49ccccc48cebc1ac9cb2dad0ef 336 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 20 201 1.4E-16 T 11-11-2016 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal AUP74_RS16420 3d572e49ccccc48cebc1ac9cb2dad0ef 336 SMART SM00342 245 327 1.3E-21 T 11-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AUP74_RS06130 21c3e1afeb16e5d4ecea5ed1148ddbce 415 Pfam PF06097 Bacterial protein of unknown function (DUF945) 7 180 1.0E-15 T 11-11-2016 IPR010352 Protein of unknown function DUF945 AUP74_RS01405 a8b7651b111b06a856c0622e5142348a 134 Gene3D G3DSA:2.60.120.10 14 110 5.2E-17 T 11-11-2016 IPR014710 RmlC-like jelly roll fold AUP74_RS01405 a8b7651b111b06a856c0622e5142348a 134 ProDom PD080544 SYNTHASE 4.2.1.- LYASE L-ECTOINE DEHYDRATASE N-ACETYLDIAMINOBUTYRATE ECTOINE ENZYME SYNTHASE:ECTOINE ECTC 1 120 2.0E-51 T 11-11-2016 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AUP74_RS01405 a8b7651b111b06a856c0622e5142348a 134 Hamap MF_01255 L-ectoine synthase [ectC]. 1 127 36.507 T 11-11-2016 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AUP74_RS01405 a8b7651b111b06a856c0622e5142348a 134 Pfam PF06339 Ectoine synthase 1 126 1.8E-61 T 11-11-2016 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AUP74_RS01405 a8b7651b111b06a856c0622e5142348a 134 SUPERFAMILY SSF51182 5 123 1.59E-22 T 11-11-2016 IPR011051 RmlC-like cupin domain AUP74_RS11945 28704499b35562cacc626bd8e1f04999 354 Pfam PF02424 ApbE family 47 328 2.0E-88 T 11-11-2016 IPR024932 Flavin transferase ApbE GO:0017013 AUP74_RS11945 28704499b35562cacc626bd8e1f04999 354 PIRSF PIRSF006268 15 350 4.0E-93 T 11-11-2016 IPR024932 Flavin transferase ApbE GO:0017013 AUP74_RS11945 28704499b35562cacc626bd8e1f04999 354 SUPERFAMILY SSF143631 39 349 4.45E-104 T 11-11-2016 IPR003374 ApbE-like domain AUP74_RS16505 cabee293788c3652878e8b29d3eb818a 116 SUPERFAMILY SSF159888 8 108 6.93E-18 T 11-11-2016 AUP74_RS16505 cabee293788c3652878e8b29d3eb818a 116 Pfam PF08818 Domain of unknown function (DU1801) 19 107 7.9E-14 T 11-11-2016 IPR014922 Domain of unknown function DUF1801 AUP74_RS11835 165a68603852d3cf4584ec617080b2a0 145 PRINTS PR01438 Universal stress protein signature 119 141 1.2E-17 T 11-11-2016 IPR006015 Universal stress protein A AUP74_RS11835 165a68603852d3cf4584ec617080b2a0 145 PRINTS PR01438 Universal stress protein signature 4 22 1.2E-17 T 11-11-2016 IPR006015 Universal stress protein A AUP74_RS11835 165a68603852d3cf4584ec617080b2a0 145 PRINTS PR01438 Universal stress protein signature 102 114 1.2E-17 T 11-11-2016 IPR006015 Universal stress protein A AUP74_RS11835 165a68603852d3cf4584ec617080b2a0 145 Gene3D G3DSA:3.40.50.620 4 142 4.9E-41 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS11835 165a68603852d3cf4584ec617080b2a0 145 Pfam PF00582 Universal stress protein family 4 141 7.7E-35 T 11-11-2016 IPR006016 UspA GO:0006950 AUP74_RS11835 165a68603852d3cf4584ec617080b2a0 145 PIRSF PIRSF006276 1 144 1.1E-44 T 11-11-2016 IPR006015 Universal stress protein A AUP74_RS11835 165a68603852d3cf4584ec617080b2a0 145 SUPERFAMILY SSF52402 4 141 1.09E-38 T 11-11-2016 AUP74_RS04365 2e2020b6ff846bdb1d2a849acfabb388 299 SUPERFAMILY SSF161111 3 207 4.05E-35 T 11-11-2016 AUP74_RS04365 2e2020b6ff846bdb1d2a849acfabb388 299 Gene3D G3DSA:1.20.1510.10 6 207 7.9E-25 T 11-11-2016 IPR027469 Cation efflux protein transmembrane domain AUP74_RS04365 2e2020b6ff846bdb1d2a849acfabb388 299 Pfam PF01545 Cation efflux family 9 206 1.6E-34 T 11-11-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AUP74_RS04365 2e2020b6ff846bdb1d2a849acfabb388 299 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 6 257 3.9E-28 T 11-11-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AUP74_RS11930 752168441def52e989f9d1980820774f 218 Hamap MF_00428 Na(+)-translocating NADH-quinone reductase subunit D [nqrD]. 1 203 34.099 T 11-11-2016 IPR011292 Na(+)-translocating NADH-quinone reductase subunit D GO:0016655|GO:0055114 AUP74_RS11930 752168441def52e989f9d1980820774f 218 PIRSF PIRSF006102 1 209 6.0E-63 T 11-11-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 AUP74_RS11930 752168441def52e989f9d1980820774f 218 Pfam PF02508 Rnf-Nqr subunit, membrane protein 5 190 1.3E-58 T 11-11-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 AUP74_RS11930 752168441def52e989f9d1980820774f 218 TIGRFAM TIGR01939 nqrD: NADH:ubiquinone oxidoreductase, Na(+)-translocating, D subunit 2 203 5.0E-96 T 11-11-2016 IPR011292 Na(+)-translocating NADH-quinone reductase subunit D GO:0016655|GO:0055114 AUP74_RS08620 8179b5e701c6f1bac824a9a22f9dd1ad 353 SUPERFAMILY SSF89733 5 346 7.72E-82 T 11-11-2016 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 AUP74_RS08620 8179b5e701c6f1bac824a9a22f9dd1ad 353 Pfam PF02615 Malate/L-lactate dehydrogenase 7 337 8.2E-87 T 11-11-2016 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 AUP74_RS08620 8179b5e701c6f1bac824a9a22f9dd1ad 353 Gene3D G3DSA:1.10.1530.10 4 74 2.0E-17 T 11-11-2016 AUP74_RS08620 8179b5e701c6f1bac824a9a22f9dd1ad 353 Gene3D G3DSA:3.30.1370.60 75 277 8.9E-54 T 11-11-2016 AUP74_RS05050 6ccf3dc95e69ef78df049c18993041ba 471 SUPERFAMILY SSF51735 140 272 4.72E-5 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS05050 6ccf3dc95e69ef78df049c18993041ba 471 TIGRFAM TIGR03023 WcaJ_sugtrans: undecaprenyl-phosphate glucose phosphotransferase 38 471 4.6E-162 T 11-11-2016 IPR017473 Undecaprenyl-phosphate glucose phosphotransferase, WcaJ MetaCyc: PWY-6655|MetaCyc: PWY-6658 AUP74_RS05050 6ccf3dc95e69ef78df049c18993041ba 471 Pfam PF02397 Bacterial sugar transferase 281 463 3.7E-56 T 11-11-2016 IPR003362 Bacterial sugar transferase AUP74_RS05050 6ccf3dc95e69ef78df049c18993041ba 471 Pfam PF13727 CoA-binding domain 63 245 1.5E-32 T 11-11-2016 AUP74_RS05050 6ccf3dc95e69ef78df049c18993041ba 471 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 23 471 2.0E-143 T 11-11-2016 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase AUP74_RS14500 0048c5aea1899ef37e7639cfbb29839f 403 SUPERFAMILY SSF103473 3 388 1.02E-60 T 11-11-2016 IPR020846 Major facilitator superfamily domain AUP74_RS14500 0048c5aea1899ef37e7639cfbb29839f 403 PRINTS PR01035 Tetracycline resistance protein signature 10 26 7.4E-27 T 11-11-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 AUP74_RS14500 0048c5aea1899ef37e7639cfbb29839f 403 PRINTS PR01035 Tetracycline resistance protein signature 67 91 7.4E-27 T 11-11-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 AUP74_RS14500 0048c5aea1899ef37e7639cfbb29839f 403 PRINTS PR01035 Tetracycline resistance protein signature 94 115 7.4E-27 T 11-11-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 AUP74_RS14500 0048c5aea1899ef37e7639cfbb29839f 403 PRINTS PR01035 Tetracycline resistance protein signature 124 146 7.4E-27 T 11-11-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 AUP74_RS14500 0048c5aea1899ef37e7639cfbb29839f 403 PRINTS PR01035 Tetracycline resistance protein signature 272 293 7.4E-27 T 11-11-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 AUP74_RS14500 0048c5aea1899ef37e7639cfbb29839f 403 PRINTS PR01035 Tetracycline resistance protein signature 332 355 7.4E-27 T 11-11-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 AUP74_RS14500 0048c5aea1899ef37e7639cfbb29839f 403 Pfam PF07690 Major Facilitator Superfamily 5 258 4.2E-32 T 11-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AUP74_RS14500 0048c5aea1899ef37e7639cfbb29839f 403 Gene3D G3DSA:1.20.1250.20 206 388 2.7E-23 T 11-11-2016 AUP74_RS14500 0048c5aea1899ef37e7639cfbb29839f 403 Gene3D G3DSA:1.20.1250.20 3 186 9.4E-37 T 11-11-2016 AUP74_RS07320 341049c11b9acb7649dc67548aa637a0 164 SUPERFAMILY SSF46785 13 158 1.75E-32 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS07320 341049c11b9acb7649dc67548aa637a0 164 Gene3D G3DSA:1.10.10.10 15 158 5.7E-37 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS07320 341049c11b9acb7649dc67548aa637a0 164 SMART SM00347 41 147 9.8E-15 T 11-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AUP74_RS07320 341049c11b9acb7649dc67548aa637a0 164 Pfam PF01047 MarR family 48 110 6.8E-11 T 11-11-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AUP74_RS16835 db66e97b6df3d3d8fdcdd3f3aaec2635 205 Pfam PF06930 Protein of unknown function (DUF1282) 10 184 3.8E-42 T 11-11-2016 IPR009698 Protein of unknown function DUF1282 AUP74_RS13795 11c0cfc7e98b89ab57a6be663cac616b 230 Pfam PF10707 PhoP regulatory network protein YrbL 3 201 5.5E-42 T 11-11-2016 IPR019647 PhoP regulatory network protein YrbL AUP74_RS07975 864d1722051aae9ca1cb13036d95707f 148 Pfam PF13689 Domain of unknown function (DUF4154) 3 144 2.2E-25 T 11-11-2016 IPR025293 Protein of unknown function DUF4154 AUP74_RS09170 5e42bf99f9f96b298bdba77321f577e8 240 PIRSF PIRSF006170 1 221 1.3E-60 T 11-11-2016 IPR026039 Uncharacterised protein family UPF0070 AUP74_RS09170 5e42bf99f9f96b298bdba77321f577e8 240 SUPERFAMILY SSF48452 98 196 8.06E-5 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS09170 5e42bf99f9f96b298bdba77321f577e8 240 Pfam PF09976 Tetratricopeptide repeat-like domain 15 215 3.9E-55 T 11-11-2016 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038 AUP74_RS15925 f51e94632121ddf74fa04c9eab32137e 349 SUPERFAMILY SSF51735 2 133 8.95E-20 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS15925 f51e94632121ddf74fa04c9eab32137e 349 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 2 117 2.4E-15 T 11-11-2016 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 AUP74_RS15925 f51e94632121ddf74fa04c9eab32137e 349 Gene3D G3DSA:3.40.50.720 2 155 7.0E-24 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS01340 08a4e794ab30c11bbaf5e1f430315f38 190 SMART SM00782 6 51 2.9E-5 T 11-11-2016 IPR013991 PhnA protein N-terminal, proteobacterial AUP74_RS01340 08a4e794ab30c11bbaf5e1f430315f38 190 Gene3D G3DSA:2.30.30.40 121 188 2.3E-27 T 11-11-2016 AUP74_RS01340 08a4e794ab30c11bbaf5e1f430315f38 190 SUPERFAMILY SSF82057 118 188 2.56E-25 T 11-11-2016 AUP74_RS01340 08a4e794ab30c11bbaf5e1f430315f38 190 Pfam PF03831 PhnA domain 123 188 1.1E-27 T 11-11-2016 IPR013988 PhnA protein, C-terminal AUP74_RS14385 ee80cfcb31f47e223327e63de77198da 277 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 5 213 1.5E-32 T 11-11-2016 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 AUP74_RS14385 ee80cfcb31f47e223327e63de77198da 277 PIRSF PIRSF015582 1 276 5.6E-70 T 11-11-2016 IPR011206 Citrate lyase beta subunit-like AUP74_RS14385 ee80cfcb31f47e223327e63de77198da 277 Gene3D G3DSA:3.20.20.60 4 225 4.4E-65 T 11-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AUP74_RS14385 ee80cfcb31f47e223327e63de77198da 277 SUPERFAMILY SSF51621 3 223 2.41E-55 T 11-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AUP74_RS01200 ee8127b0a10a66fac4d212cd268877fa 187 Gene3D G3DSA:1.10.10.10 6 83 4.6E-23 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS01200 ee8127b0a10a66fac4d212cd268877fa 187 Pfam PF12802 MarR family 22 80 1.2E-8 T 11-11-2016 AUP74_RS01200 ee8127b0a10a66fac4d212cd268877fa 187 PIRSF PIRSF006707 1 176 2.8E-48 T 11-11-2016 IPR026282 DNA-binding protein, MJ1563 type AUP74_RS01200 ee8127b0a10a66fac4d212cd268877fa 187 SUPERFAMILY SSF46785 7 142 1.37E-22 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS03505 fefcecfd8affc3ec36df5533b21b88da 125 Pfam PF01479 S4 domain 4 48 6.0E-12 T 11-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 AUP74_RS03505 fefcecfd8affc3ec36df5533b21b88da 125 SUPERFAMILY SSF55174 2 99 4.06E-27 T 11-11-2016 AUP74_RS03505 fefcecfd8affc3ec36df5533b21b88da 125 Gene3D G3DSA:3.10.290.10 2 98 6.2E-35 T 11-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 AUP74_RS03505 fefcecfd8affc3ec36df5533b21b88da 125 PIRSF PIRSF016821 1 125 3.6E-41 T 11-11-2016 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 AUP74_RS03505 fefcecfd8affc3ec36df5533b21b88da 125 SMART SM00363 4 67 2.9E-7 T 11-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 AUP74_RS16375 140b7c581d2e77d5216d44bfcb2efe0b 206 Pfam PF01613 Flavin reductase like domain 27 167 8.3E-19 T 11-11-2016 IPR002563 Flavin reductase like domain GO:0010181 AUP74_RS16375 140b7c581d2e77d5216d44bfcb2efe0b 206 SMART SM00903 23 176 1.3E-15 T 11-11-2016 IPR002563 Flavin reductase like domain GO:0010181 AUP74_RS16375 140b7c581d2e77d5216d44bfcb2efe0b 206 SUPERFAMILY SSF50475 5 190 2.36E-50 T 11-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 AUP74_RS16375 140b7c581d2e77d5216d44bfcb2efe0b 206 Gene3D G3DSA:2.30.110.10 14 188 1.2E-67 T 11-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 AUP74_RS07760 c9de088d5e41682dd15a6c6c4415a9ae 387 Pfam PF13480 Acetyltransferase (GNAT) domain 175 319 1.1E-17 T 11-11-2016 AUP74_RS07760 c9de088d5e41682dd15a6c6c4415a9ae 387 Gene3D G3DSA:3.40.630.30 178 323 7.9E-4 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS07760 c9de088d5e41682dd15a6c6c4415a9ae 387 SUPERFAMILY SSF55729 175 325 3.41E-18 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS01600 0a8ab595f895384a63235c860f8a239a 190 Gene3D G3DSA:1.20.120.520 3 159 1.8E-13 T 11-11-2016 AUP74_RS01600 0a8ab595f895384a63235c860f8a239a 190 Pfam PF01814 Hemerythrin HHE cation binding domain 4 140 4.4E-9 T 11-11-2016 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 AUP74_RS02925 87cb4c5a7b28591c5c737885b5878a64 758 ProSitePatterns PS00018 EF-hand calcium-binding domain. 637 649 - T 11-11-2016 IPR018247 EF-Hand 1, calcium-binding site AUP74_RS02925 87cb4c5a7b28591c5c737885b5878a64 758 SUPERFAMILY SSF49299 24 113 6.67E-5 T 11-11-2016 IPR000601 PKD domain AUP74_RS02925 87cb4c5a7b28591c5c737885b5878a64 758 Gene3D G3DSA:2.60.40.670 26 111 1.8E-4 T 11-11-2016 IPR000601 PKD domain AUP74_RS05380 e7d1539654df3640cecdba802b300f3f 191 Pfam PF13302 Acetyltransferase (GNAT) domain 11 152 3.2E-32 T 11-11-2016 IPR000182 GNAT domain GO:0008080 AUP74_RS05380 e7d1539654df3640cecdba802b300f3f 191 Gene3D G3DSA:3.40.630.30 6 183 5.4E-50 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS05380 e7d1539654df3640cecdba802b300f3f 191 SUPERFAMILY SSF55729 7 176 1.24E-39 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS03740 a847fd405ae0b7db6fea01a578d8fe30 133 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 59 110 6.0E-20 T 11-11-2016 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 AUP74_RS03740 a847fd405ae0b7db6fea01a578d8fe30 133 SUPERFAMILY SSF141734 10 126 3.53E-49 T 11-11-2016 AUP74_RS03740 a847fd405ae0b7db6fea01a578d8fe30 133 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 10 114 33.003 T 11-11-2016 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 AUP74_RS03740 a847fd405ae0b7db6fea01a578d8fe30 133 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 36 110 2.8E-34 T 11-11-2016 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 AUP74_RS08490 26403eccbbff8dcc15c417bfc61d20cf 334 Pfam PF13621 Cupin-like domain 20 257 1.7E-51 T 11-11-2016 AUP74_RS08490 26403eccbbff8dcc15c417bfc61d20cf 334 SUPERFAMILY SSF51197 22 296 7.55E-56 T 11-11-2016 AUP74_RS08490 26403eccbbff8dcc15c417bfc61d20cf 334 Gene3D G3DSA:2.60.120.650 22 254 1.3E-39 T 11-11-2016 AUP74_RS08490 26403eccbbff8dcc15c417bfc61d20cf 334 SMART SM00558 75 269 1.4E-4 T 11-11-2016 IPR003347 JmjC domain AUP74_RS13090 11fcf0b21cd951cf4c4dc19fa240cbed 196 TIGRFAM TIGR00172 maf: septum formation protein Maf 1 185 9.5E-52 T 11-11-2016 IPR003697 Maf-like protein GO:0005737 AUP74_RS13090 11fcf0b21cd951cf4c4dc19fa240cbed 196 SUPERFAMILY SSF52972 2 187 7.85E-58 T 11-11-2016 IPR029001 Inosine triphosphate pyrophosphatase-like AUP74_RS13090 11fcf0b21cd951cf4c4dc19fa240cbed 196 Gene3D G3DSA:3.90.950.10 3 190 3.3E-58 T 11-11-2016 IPR029001 Inosine triphosphate pyrophosphatase-like AUP74_RS13090 11fcf0b21cd951cf4c4dc19fa240cbed 196 Hamap MF_00528 Septum formation protein Maf [maf]. 4 192 30.089 T 11-11-2016 IPR003697 Maf-like protein GO:0005737 AUP74_RS13090 11fcf0b21cd951cf4c4dc19fa240cbed 196 Pfam PF02545 Maf-like protein 4 187 3.3E-45 T 11-11-2016 IPR003697 Maf-like protein GO:0005737 AUP74_RS13090 11fcf0b21cd951cf4c4dc19fa240cbed 196 PIRSF PIRSF006305 1 194 3.7E-43 T 11-11-2016 IPR003697 Maf-like protein GO:0005737 AUP74_RS12010 0090e1693bcd74ed1c6b5e6a06c21d1c 543 Pfam PF15420 Alpha/beta-hydrolase family N-terminus 23 230 9.1E-65 T 11-11-2016 IPR027788 Alpha/beta-hydrolase, N-terminal domain AUP74_RS12010 0090e1693bcd74ed1c6b5e6a06c21d1c 543 Pfam PF10081 Alpha/beta-hydrolase family 246 532 4.7E-116 T 11-11-2016 IPR027787 Alpha/beta-hydrolase, catalytic domain AUP74_RS12010 0090e1693bcd74ed1c6b5e6a06c21d1c 543 PIRSF PIRSF007542 1 543 8.9E-218 T 11-11-2016 IPR012037 Alpha/beta-hydrolase family AUP74_RS04980 34cac57b39b48cca8f70e076d615e2bb 329 TIGRFAM TIGR00367 TIGR00367: K+-dependent Na+/Ca+ exchanger homolog 2 314 8.4E-71 T 11-11-2016 IPR004481 Sodium/potassium/calcium exchanger Reactome: R-HSA-425561 AUP74_RS04980 34cac57b39b48cca8f70e076d615e2bb 329 Pfam PF01699 Sodium/calcium exchanger protein 4 144 1.8E-26 T 11-11-2016 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 AUP74_RS04980 34cac57b39b48cca8f70e076d615e2bb 329 Pfam PF01699 Sodium/calcium exchanger protein 174 318 7.1E-33 T 11-11-2016 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 AUP74_RS14560 971c875f7d42666e1053ffb87de192dd 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 8.1E-5 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS14560 971c875f7d42666e1053ffb87de192dd 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 8.1E-5 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS14560 971c875f7d42666e1053ffb87de192dd 268 SUPERFAMILY SSF51735 1 245 7.28E-51 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS14560 971c875f7d42666e1053ffb87de192dd 268 Pfam PF00106 short chain dehydrogenase 2 191 3.0E-41 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS14560 971c875f7d42666e1053ffb87de192dd 268 Gene3D G3DSA:3.40.50.720 2 245 5.3E-52 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS14560 971c875f7d42666e1053ffb87de192dd 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.1E-21 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS14560 971c875f7d42666e1053ffb87de192dd 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 1.1E-21 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS14560 971c875f7d42666e1053ffb87de192dd 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 1.1E-21 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS14560 971c875f7d42666e1053ffb87de192dd 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.1E-21 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS14560 971c875f7d42666e1053ffb87de192dd 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.1E-21 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS01240 24c3ab3a7eafffc731b74396e424e0f2 200 Gene3D G3DSA:3.40.30.10 1 81 6.2E-17 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS01240 24c3ab3a7eafffc731b74396e424e0f2 200 SUPERFAMILY SSF47616 71 196 1.82E-10 T 11-11-2016 IPR010987 Glutathione S-transferase, C-terminal-like AUP74_RS01240 24c3ab3a7eafffc731b74396e424e0f2 200 Gene3D G3DSA:1.20.1050.10 123 196 1.4E-4 T 11-11-2016 IPR010987 Glutathione S-transferase, C-terminal-like AUP74_RS01240 24c3ab3a7eafffc731b74396e424e0f2 200 SUPERFAMILY SSF52833 1 81 8.24E-15 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS01240 24c3ab3a7eafffc731b74396e424e0f2 200 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 75 2.0E-16 T 11-11-2016 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 AUP74_RS09215 92142419571d9ceeba755935c0b92dd8 276 SMART SM00849 23 196 1.0E-20 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS09215 92142419571d9ceeba755935c0b92dd8 276 SUPERFAMILY SSF56281 21 242 9.07E-37 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS09215 92142419571d9ceeba755935c0b92dd8 276 Gene3D G3DSA:3.60.15.10 22 226 3.0E-30 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS09215 92142419571d9ceeba755935c0b92dd8 276 Pfam PF00753 Metallo-beta-lactamase superfamily 22 196 8.7E-14 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS10550 314fdf21b023c23ae8b964b07105a437 376 Gene3D G3DSA:3.40.50.10330 77 165 1.6E-5 T 11-11-2016 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 AUP74_RS10550 314fdf21b023c23ae8b964b07105a437 376 SUPERFAMILY SSF111331 74 169 4.74E-8 T 11-11-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain AUP74_RS10550 314fdf21b023c23ae8b964b07105a437 376 SUPERFAMILY SSF111331 2 33 4.74E-8 T 11-11-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain AUP74_RS10550 314fdf21b023c23ae8b964b07105a437 376 PIRSF PIRSF016907 1 373 3.5E-124 T 11-11-2016 IPR011386 Putative ATP-NAD kinase AUP74_RS10550 314fdf21b023c23ae8b964b07105a437 376 Pfam PF01513 ATP-NAD kinase 3 368 2.0E-48 T 11-11-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 AUP74_RS06210 a30ddf3070fe9206cde55772cd61b211 362 SMART SM00387 256 361 0.0033 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS06210 a30ddf3070fe9206cde55772cd61b211 362 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 264 360 4.0E-8 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS06210 a30ddf3070fe9206cde55772cd61b211 362 Pfam PF06580 Histidine kinase 165 245 2.3E-24 T 11-11-2016 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 AUP74_RS06210 a30ddf3070fe9206cde55772cd61b211 362 SUPERFAMILY SSF55874 223 358 1.23E-18 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS06210 a30ddf3070fe9206cde55772cd61b211 362 PRINTS PR00344 Bacterial sensor protein C-terminal signature 297 311 3.6E-5 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS06210 a30ddf3070fe9206cde55772cd61b211 362 PRINTS PR00344 Bacterial sensor protein C-terminal signature 345 358 3.6E-5 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS06210 a30ddf3070fe9206cde55772cd61b211 362 PRINTS PR00344 Bacterial sensor protein C-terminal signature 318 336 3.6E-5 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AUP74_RS06210 a30ddf3070fe9206cde55772cd61b211 362 Gene3D G3DSA:3.30.565.10 217 361 2.7E-19 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS01080 e612198cb65ad67984704825a2aeb363 755 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 47 100 8.1E-12 T 11-11-2016 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS01080 e612198cb65ad67984704825a2aeb363 755 Pfam PF00361 Proton-conducting membrane transporter 113 396 1.6E-62 T 11-11-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS01080 e612198cb65ad67984704825a2aeb363 755 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 338 360 1.3E-5 T 11-11-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 AUP74_RS01080 e612198cb65ad67984704825a2aeb363 755 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 64 84 1.3E-5 T 11-11-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 AUP74_RS01080 e612198cb65ad67984704825a2aeb363 755 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 243 265 1.3E-5 T 11-11-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 AUP74_RS01080 e612198cb65ad67984704825a2aeb363 755 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 62 87 1.6E-33 T 11-11-2016 AUP74_RS01080 e612198cb65ad67984704825a2aeb363 755 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 225 251 1.6E-33 T 11-11-2016 AUP74_RS01080 e612198cb65ad67984704825a2aeb363 755 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 203 224 1.6E-33 T 11-11-2016 AUP74_RS01080 e612198cb65ad67984704825a2aeb363 755 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 90 110 1.6E-33 T 11-11-2016 AUP74_RS01080 e612198cb65ad67984704825a2aeb363 755 Pfam PF13244 Domain of unknown function (DUF4040) 594 657 3.1E-14 T 11-11-2016 IPR025383 Domain of unknown function DUF4040 AUP74_RS10360 dda9e3b19f4866c5c8bbc1678d297473 1324 Pfam PF13502 AsmA-like C-terminal region 215 473 3.3E-6 T 11-11-2016 IPR032712 AsmA-like, C-terminal AUP74_RS10360 dda9e3b19f4866c5c8bbc1678d297473 1324 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 761 952 2.2E-7 T 11-11-2016 IPR007452 Translocation and assembly module TamB AUP74_RS10360 dda9e3b19f4866c5c8bbc1678d297473 1324 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 978 1324 1.5E-46 T 11-11-2016 IPR007452 Translocation and assembly module TamB AUP74_RS15845 27af729b6b65d1050092beda2686fa5b 477 SUPERFAMILY SSF53720 7 474 1.26E-156 T 11-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AUP74_RS15845 27af729b6b65d1050092beda2686fa5b 477 Pfam PF00171 Aldehyde dehydrogenase family 18 473 2.9E-158 T 11-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 AUP74_RS15845 27af729b6b65d1050092beda2686fa5b 477 Gene3D G3DSA:3.40.605.10 10 261 9.0E-90 T 11-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AUP74_RS15845 27af729b6b65d1050092beda2686fa5b 477 Gene3D G3DSA:3.40.309.10 262 448 1.2E-63 T 11-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 AUP74_RS15845 27af729b6b65d1050092beda2686fa5b 477 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 277 288 - T 11-11-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 AUP74_RS12195 0597e83871b18454576c71a978d77b4d 206 Pfam PF01618 MotA/TolQ/ExbB proton channel family 68 188 4.0E-36 T 11-11-2016 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 AUP74_RS04690 2eb1819f180e5516adc7d6dd70c08ce4 516 Gene3D G3DSA:1.20.210.10 7 515 2.0E-214 T 11-11-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS04690 2eb1819f180e5516adc7d6dd70c08ce4 516 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 240 294 - T 11-11-2016 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS04690 2eb1819f180e5516adc7d6dd70c08ce4 516 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 12 514 3.9E-214 T 11-11-2016 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 AUP74_RS04690 2eb1819f180e5516adc7d6dd70c08ce4 516 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 20 463 6.2E-151 T 11-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS04690 2eb1819f180e5516adc7d6dd70c08ce4 516 SUPERFAMILY SSF81442 8 515 6.02E-195 T 11-11-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS04690 2eb1819f180e5516adc7d6dd70c08ce4 516 PRINTS PR01165 Cytochrome c oxidase subunit I signature 238 259 1.9E-123 T 11-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS04690 2eb1819f180e5516adc7d6dd70c08ce4 516 PRINTS PR01165 Cytochrome c oxidase subunit I signature 158 176 1.9E-123 T 11-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS04690 2eb1819f180e5516adc7d6dd70c08ce4 516 PRINTS PR01165 Cytochrome c oxidase subunit I signature 58 81 1.9E-123 T 11-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS04690 2eb1819f180e5516adc7d6dd70c08ce4 516 PRINTS PR01165 Cytochrome c oxidase subunit I signature 128 140 1.9E-123 T 11-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS04690 2eb1819f180e5516adc7d6dd70c08ce4 516 PRINTS PR01165 Cytochrome c oxidase subunit I signature 371 390 1.9E-123 T 11-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS04690 2eb1819f180e5516adc7d6dd70c08ce4 516 PRINTS PR01165 Cytochrome c oxidase subunit I signature 11 36 1.9E-123 T 11-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS04690 2eb1819f180e5516adc7d6dd70c08ce4 516 PRINTS PR01165 Cytochrome c oxidase subunit I signature 421 442 1.9E-123 T 11-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS04690 2eb1819f180e5516adc7d6dd70c08ce4 516 PRINTS PR01165 Cytochrome c oxidase subunit I signature 187 206 1.9E-123 T 11-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS04690 2eb1819f180e5516adc7d6dd70c08ce4 516 PRINTS PR01165 Cytochrome c oxidase subunit I signature 284 299 1.9E-123 T 11-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS04690 2eb1819f180e5516adc7d6dd70c08ce4 516 PRINTS PR01165 Cytochrome c oxidase subunit I signature 308 329 1.9E-123 T 11-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS04690 2eb1819f180e5516adc7d6dd70c08ce4 516 PRINTS PR01165 Cytochrome c oxidase subunit I signature 85 109 1.9E-123 T 11-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS04690 2eb1819f180e5516adc7d6dd70c08ce4 516 PRINTS PR01165 Cytochrome c oxidase subunit I signature 343 361 1.9E-123 T 11-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS00355 beeff029856cacaf764fb2455f5db569 710 Gene3D G3DSA:1.25.40.10 282 449 2.8E-20 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS00355 beeff029856cacaf764fb2455f5db569 710 Gene3D G3DSA:1.25.40.10 481 568 2.8E-20 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS00355 beeff029856cacaf764fb2455f5db569 710 SUPERFAMILY SSF48452 363 451 1.14E-16 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS00355 beeff029856cacaf764fb2455f5db569 710 SUPERFAMILY SSF48452 282 318 1.14E-16 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS00355 beeff029856cacaf764fb2455f5db569 710 SUPERFAMILY SSF48452 527 571 1.14E-16 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS01315 14e85b3c8e520a88c727296644d48007 134 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 28 91 4.8E-12 T 11-11-2016 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 AUP74_RS01315 14e85b3c8e520a88c727296644d48007 134 Gene3D G3DSA:3.90.1590.10 2 131 8.3E-20 T 11-11-2016 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 AUP74_RS01315 14e85b3c8e520a88c727296644d48007 134 SUPERFAMILY SSF51316 1 132 8.89E-23 T 11-11-2016 IPR011057 Mss4-like AUP74_RS15745 f91c08946f9089e80074fcb09104a4a2 207 Pfam PF01300 Telomere recombination 23 198 2.0E-45 T 11-11-2016 IPR006070 YrdC-like domain GO:0003725 AUP74_RS15745 f91c08946f9089e80074fcb09104a4a2 207 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 205 1.0E-61 T 11-11-2016 IPR006070 YrdC-like domain GO:0003725 AUP74_RS15745 f91c08946f9089e80074fcb09104a4a2 207 Gene3D G3DSA:3.90.870.10 3 205 1.3E-64 T 11-11-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain AUP74_RS15745 f91c08946f9089e80074fcb09104a4a2 207 SUPERFAMILY SSF55821 2 205 2.17E-65 T 11-11-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain AUP74_RS10965 acb9ec3c8abcf0349f410de0336111e6 373 SMART SM00771 229 359 2.7E-55 T 11-11-2016 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0000917|GO:0016021 AUP74_RS10965 acb9ec3c8abcf0349f410de0336111e6 373 Hamap MF_00509 Cell division protein ZipA [zipA]. 3 361 21.012 T 11-11-2016 IPR011919 Cell division protein ZipA GO:0000917|GO:0007049|GO:0016021 AUP74_RS10965 acb9ec3c8abcf0349f410de0336111e6 373 Pfam PF04354 ZipA, C-terminal FtsZ-binding domain 231 358 1.1E-48 T 11-11-2016 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0000917|GO:0016021 AUP74_RS10965 acb9ec3c8abcf0349f410de0336111e6 373 ProDom PD035754 CELL DIVISION MEMBRANE ZIPA SEPTATION TRANSMEMBRANE HOMOLOG INNER CYCLE ZIPA 232 361 7.0E-34 T 11-11-2016 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0000917|GO:0016021 AUP74_RS10965 acb9ec3c8abcf0349f410de0336111e6 373 TIGRFAM TIGR02205 septum_zipA: cell division protein ZipA 5 359 4.2E-54 T 11-11-2016 IPR011919 Cell division protein ZipA GO:0000917|GO:0007049|GO:0016021 AUP74_RS10965 acb9ec3c8abcf0349f410de0336111e6 373 Gene3D G3DSA:3.30.1400.10 229 365 1.1E-54 T 11-11-2016 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0000917|GO:0016021 AUP74_RS10965 acb9ec3c8abcf0349f410de0336111e6 373 SUPERFAMILY SSF64383 229 365 9.15E-47 T 11-11-2016 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0000917|GO:0016021 AUP74_RS08590 f65447931563ef2413e7540d2b5206af 105 Pfam PF13937 Domain of unknown function (DUF4212) 10 86 5.3E-36 T 11-11-2016 IPR019886 Sodium symporter small subunit, predicted AUP74_RS08590 f65447931563ef2413e7540d2b5206af 105 TIGRFAM TIGR03647 Na_symport_sm: putative solute:sodium symporter small subunit 12 87 1.4E-36 T 11-11-2016 IPR019886 Sodium symporter small subunit, predicted AUP74_RS06920 66d46fdb3e667466648ed991c0fa6538 144 Gene3D G3DSA:3.100.10.10 32 143 1.1E-27 T 11-11-2016 AUP74_RS06920 66d46fdb3e667466648ed991c0fa6538 144 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 143 19.443 T 11-11-2016 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 AUP74_RS06920 66d46fdb3e667466648ed991c0fa6538 144 SUPERFAMILY SSF52080 4 143 2.62E-46 T 11-11-2016 IPR021131 Ribosomal protein L18e/L15P AUP74_RS06920 66d46fdb3e667466648ed991c0fa6538 144 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 143 1.0E-48 T 11-11-2016 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS06920 66d46fdb3e667466648ed991c0fa6538 144 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 143 8.1E-32 T 11-11-2016 IPR021131 Ribosomal protein L18e/L15P AUP74_RS14975 47cad788374818bfb3f894625ea34485 935 SUPERFAMILY SSF56935 300 348 5.49E-94 T 11-11-2016 AUP74_RS14975 47cad788374818bfb3f894625ea34485 935 SUPERFAMILY SSF56935 747 935 5.49E-94 T 11-11-2016 AUP74_RS14975 47cad788374818bfb3f894625ea34485 935 SUPERFAMILY SSF56935 391 451 5.49E-94 T 11-11-2016 AUP74_RS14975 47cad788374818bfb3f894625ea34485 935 SUPERFAMILY SSF56935 509 720 5.49E-94 T 11-11-2016 AUP74_RS14975 47cad788374818bfb3f894625ea34485 935 SUPERFAMILY SSF56935 38 240 5.49E-94 T 11-11-2016 AUP74_RS14975 47cad788374818bfb3f894625ea34485 935 Gene3D G3DSA:2.40.170.20 175 238 2.5E-82 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS14975 47cad788374818bfb3f894625ea34485 935 Gene3D G3DSA:2.40.170.20 504 935 2.5E-82 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS14975 47cad788374818bfb3f894625ea34485 935 Gene3D G3DSA:2.40.170.20 386 457 2.5E-82 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS14975 47cad788374818bfb3f894625ea34485 935 Gene3D G3DSA:2.40.170.20 273 347 2.5E-82 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS14975 47cad788374818bfb3f894625ea34485 935 Pfam PF07715 TonB-dependent Receptor Plug Domain 52 174 1.3E-20 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS14975 47cad788374818bfb3f894625ea34485 935 Pfam PF00593 TonB dependent receptor 614 933 2.4E-19 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS14975 47cad788374818bfb3f894625ea34485 935 Gene3D G3DSA:2.170.130.10 39 174 1.5E-28 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS15290 3bb2238285fcf51896f2811e39c65529 363 SUPERFAMILY SSF53756 25 357 1.94E-22 T 11-11-2016 AUP74_RS15290 3bb2238285fcf51896f2811e39c65529 363 Gene3D G3DSA:3.40.50.2000 187 304 1.0E-10 T 11-11-2016 AUP74_RS15290 3bb2238285fcf51896f2811e39c65529 363 Pfam PF12038 Domain of unknown function (DUF3524) 2 172 8.1E-57 T 11-11-2016 IPR022701 Glycosyltransferase family 1, N-terminal AUP74_RS15290 3bb2238285fcf51896f2811e39c65529 363 Pfam PF00534 Glycosyl transferases group 1 188 304 4.6E-7 T 11-11-2016 IPR001296 Glycosyl transferase, family 1 AUP74_RS10120 72320d07d86a1d72be90d141931312d1 109 PIRSF PIRSF025560 1 109 1.2E-29 T 11-11-2016 IPR008309 Uncharacterised conserved protein UCP025560 AUP74_RS10120 72320d07d86a1d72be90d141931312d1 109 Pfam PF07027 Protein of unknown function (DUF1318) 20 109 4.8E-29 T 11-11-2016 IPR008309 Uncharacterised conserved protein UCP025560 AUP74_RS01185 f9e8eae168ba4d0618234b14801b627b 384 Gene3D G3DSA:3.40.710.10 12 368 5.6E-77 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS01185 f9e8eae168ba4d0618234b14801b627b 384 Pfam PF00144 Beta-lactamase 27 369 8.7E-66 T 11-11-2016 IPR001466 Beta-lactamase-related AUP74_RS01185 f9e8eae168ba4d0618234b14801b627b 384 SUPERFAMILY SSF56601 26 358 2.82E-71 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS01135 aeca2ad5c87934488a3209a4b4416ed5 198 Pfam PF01966 HD domain 58 127 5.4E-5 T 11-11-2016 IPR006674 HD domain AUP74_RS01135 aeca2ad5c87934488a3209a4b4416ed5 198 SUPERFAMILY SSF109604 8 137 1.32E-27 T 11-11-2016 AUP74_RS04865 68aefe8bafaefe546e545e1f88eb2e50 377 Pfam PF13673 Acetyltransferase (GNAT) domain 28 151 1.9E-15 T 11-11-2016 IPR000182 GNAT domain GO:0008080 AUP74_RS04865 68aefe8bafaefe546e545e1f88eb2e50 377 Pfam PF11814 Peptidase_C39 like family 166 368 2.1E-85 T 11-11-2016 IPR021770 Protein of unknown function DUF3335 AUP74_RS04865 68aefe8bafaefe546e545e1f88eb2e50 377 SUPERFAMILY SSF55729 8 170 2.74E-32 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS04865 68aefe8bafaefe546e545e1f88eb2e50 377 Gene3D G3DSA:3.40.630.30 9 154 2.0E-33 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS07180 2b62d389d6dea8841051108af62e0b8a 318 Pfam PF00849 RNA pseudouridylate synthase 92 245 7.9E-33 T 11-11-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS07180 2b62d389d6dea8841051108af62e0b8a 318 Pfam PF01479 S4 domain 19 61 2.5E-6 T 11-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 AUP74_RS07180 2b62d389d6dea8841051108af62e0b8a 318 Gene3D G3DSA:3.10.290.10 19 63 9.2E-7 T 11-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 AUP74_RS07180 2b62d389d6dea8841051108af62e0b8a 318 SUPERFAMILY SSF55120 75 316 1.91E-78 T 11-11-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS07180 2b62d389d6dea8841051108af62e0b8a 318 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 134 148 - T 11-11-2016 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS07180 2b62d389d6dea8841051108af62e0b8a 318 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 16 316 2.4E-98 T 11-11-2016 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS07180 2b62d389d6dea8841051108af62e0b8a 318 SUPERFAMILY SSF55174 18 67 7.23E-7 T 11-11-2016 AUP74_RS11735 1b42f391296dfe2930b06b579d4a05b7 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 28 49 3.5E-5 T 11-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 AUP74_RS11735 1b42f391296dfe2930b06b579d4a05b7 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 172 191 3.5E-5 T 11-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 AUP74_RS11735 1b42f391296dfe2930b06b579d4a05b7 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 192 211 3.5E-5 T 11-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 AUP74_RS11735 1b42f391296dfe2930b06b579d4a05b7 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 59 81 3.5E-5 T 11-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 AUP74_RS11735 1b42f391296dfe2930b06b579d4a05b7 254 Pfam PF01061 ABC-2 type transporter 22 214 4.5E-14 T 11-11-2016 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AUP74_RS05005 5bd3884df07af87b67c47d6391e61db9 317 Gene3D G3DSA:3.90.550.10 11 271 1.6E-34 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases AUP74_RS05005 5bd3884df07af87b67c47d6391e61db9 317 SUPERFAMILY SSF53448 7 296 2.08E-44 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases AUP74_RS05005 5bd3884df07af87b67c47d6391e61db9 317 Pfam PF00535 Glycosyl transferase family 2 14 151 5.0E-16 T 11-11-2016 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AUP74_RS09970 2c7cc430cbee32a2639613406015df10 179 Gene3D G3DSA:3.90.79.10 37 171 8.5E-31 T 11-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 AUP74_RS09970 2c7cc430cbee32a2639613406015df10 179 Pfam PF00293 NUDIX domain 39 144 1.6E-12 T 11-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 AUP74_RS09970 2c7cc430cbee32a2639613406015df10 179 Pfam PF14803 Nudix N-terminal 2 35 1.9E-13 T 11-11-2016 IPR029401 Nudix hydrolase, N-terminal KEGG: 00230+3.6.1.13|KEGG: 00740+3.6.1.18 AUP74_RS09970 2c7cc430cbee32a2639613406015df10 179 SUPERFAMILY SSF55811 2 165 7.99E-34 T 11-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 AUP74_RS09970 2c7cc430cbee32a2639613406015df10 179 Gene3D G3DSA:2.20.70.10 1 35 1.8E-14 T 11-11-2016 AUP74_RS01450 a9ab5409ddd1df794fa062a2eda733fe 429 PRINTS PR00834 HtrA/DegQ protease family signature 62 74 1.1E-14 T 11-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AUP74_RS01450 a9ab5409ddd1df794fa062a2eda733fe 429 PRINTS PR00834 HtrA/DegQ protease family signature 89 109 1.1E-14 T 11-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AUP74_RS01450 a9ab5409ddd1df794fa062a2eda733fe 429 PRINTS PR00834 HtrA/DegQ protease family signature 180 197 1.1E-14 T 11-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AUP74_RS01450 a9ab5409ddd1df794fa062a2eda733fe 429 PRINTS PR00834 HtrA/DegQ protease family signature 128 152 1.1E-14 T 11-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AUP74_RS01450 a9ab5409ddd1df794fa062a2eda733fe 429 SUPERFAMILY SSF50494 6 207 7.86E-36 T 11-11-2016 IPR009003 Peptidase S1, PA clan AUP74_RS01450 a9ab5409ddd1df794fa062a2eda733fe 429 Pfam PF13365 Trypsin-like peptidase domain 53 187 3.1E-24 T 11-11-2016 AUP74_RS01450 a9ab5409ddd1df794fa062a2eda733fe 429 Gene3D G3DSA:2.40.10.10 131 213 9.6E-17 T 11-11-2016 AUP74_RS01450 a9ab5409ddd1df794fa062a2eda733fe 429 Gene3D G3DSA:2.40.10.10 47 130 1.8E-14 T 11-11-2016 AUP74_RS09695 4535cb7a6b013b5ac1f1df3ee086424b 354 Gene3D G3DSA:3.40.630.10 6 76 5.9E-17 T 11-11-2016 AUP74_RS09695 4535cb7a6b013b5ac1f1df3ee086424b 354 Gene3D G3DSA:3.40.630.10 166 350 5.9E-17 T 11-11-2016 AUP74_RS09695 4535cb7a6b013b5ac1f1df3ee086424b 354 SUPERFAMILY SSF53187 5 75 1.92E-14 T 11-11-2016 AUP74_RS09695 4535cb7a6b013b5ac1f1df3ee086424b 354 SUPERFAMILY SSF53187 163 350 1.92E-14 T 11-11-2016 AUP74_RS13870 ffbd0b7b58e20c0a5b4af14052a74acf 206 Pfam PF01810 LysE type translocator 16 204 4.6E-25 T 11-11-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 AUP74_RS06335 4e1a5a93d5b0c6fb0a0835a7aa1a4d30 126 Pfam PF02152 Dihydroneopterin aldolase 4 113 2.2E-30 T 11-11-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AUP74_RS06335 4e1a5a93d5b0c6fb0a0835a7aa1a4d30 126 SUPERFAMILY SSF55620 1 114 3.89E-34 T 11-11-2016 AUP74_RS06335 4e1a5a93d5b0c6fb0a0835a7aa1a4d30 126 TIGRFAM TIGR00526 folB_dom: FolB domain 1 116 4.7E-32 T 11-11-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AUP74_RS06335 4e1a5a93d5b0c6fb0a0835a7aa1a4d30 126 SMART SM00905 4 114 1.2E-44 T 11-11-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AUP74_RS06335 4e1a5a93d5b0c6fb0a0835a7aa1a4d30 126 Gene3D G3DSA:3.30.1130.10 1 114 9.9E-39 T 11-11-2016 AUP74_RS06335 4e1a5a93d5b0c6fb0a0835a7aa1a4d30 126 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 4 114 2.6E-24 T 11-11-2016 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AUP74_RS09250 87cb99114437418d4a3bc98ec740b64b 110 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 12 110 18.121 T 11-11-2016 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 AUP74_RS09250 87cb99114437418d4a3bc98ec740b64b 110 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 18 105 1.8E-21 T 11-11-2016 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 AUP74_RS13160 be3e2c17fd683de3ef7bf85c57da2de2 132 TIGRFAM TIGR03012 sulf_tusD_dsrE: sulfur relay protein TusD/DsrE 3 128 7.5E-48 T 11-11-2016 IPR017463 Sulphur relay, TusD/DsrE GO:0005737|GO:0008033|GO:0016783 AUP74_RS13160 be3e2c17fd683de3ef7bf85c57da2de2 132 Pfam PF02635 DsrE/DsrF-like family 2 128 2.3E-29 T 11-11-2016 IPR003787 Sulphur relay, DsrE/F-like protein AUP74_RS13160 be3e2c17fd683de3ef7bf85c57da2de2 132 Gene3D G3DSA:3.40.1260.10 5 128 4.8E-30 T 11-11-2016 IPR027396 DsrEFH-like AUP74_RS13160 be3e2c17fd683de3ef7bf85c57da2de2 132 SUPERFAMILY SSF75169 1 128 7.4E-39 T 11-11-2016 IPR027396 DsrEFH-like AUP74_RS04465 aeb4d9863eee9affe2e51c4e484bc35c 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 42 3.0E-14 T 11-11-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS04465 aeb4d9863eee9affe2e51c4e484bc35c 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 11-11-2016 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS04465 aeb4d9863eee9affe2e51c4e484bc35c 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 1.7E-26 T 11-11-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS04465 aeb4d9863eee9affe2e51c4e484bc35c 44 Pfam PF00468 Ribosomal protein L34 1 44 4.5E-26 T 11-11-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS04465 aeb4d9863eee9affe2e51c4e484bc35c 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 16.545 T 11-11-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS07450 6567ee676edd31e56089d01ca78d2398 351 Pfam PF01137 RNA 3'-terminal phosphate cyclase 16 337 1.7E-77 T 11-11-2016 IPR023797 RNA 3'-terminal phosphate cyclase domain AUP74_RS07450 6567ee676edd31e56089d01ca78d2398 351 Hamap MF_00200 RNA 3'-terminal phosphate cyclase [rtcA]. 9 338 38.97 T 11-11-2016 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 AUP74_RS07450 6567ee676edd31e56089d01ca78d2398 351 SUPERFAMILY SSF55205 10 223 2.75E-63 T 11-11-2016 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 AUP74_RS07450 6567ee676edd31e56089d01ca78d2398 351 ProSitePatterns PS01287 RNA 3'-terminal phosphate cyclase signature. 162 172 - T 11-11-2016 IPR020719 RNA 3'-terminal phosphate cyclase-like, conserved site AUP74_RS07450 6567ee676edd31e56089d01ca78d2398 351 Pfam PF05189 RNA 3'-terminal phosphate cyclase (RTC), insert domain 190 285 2.7E-22 T 11-11-2016 IPR013791 RNA 3'-terminal phosphate cyclase, insert domain AUP74_RS07450 6567ee676edd31e56089d01ca78d2398 351 SUPERFAMILY SSF52913 191 288 4.18E-17 T 11-11-2016 IPR013791 RNA 3'-terminal phosphate cyclase, insert domain AUP74_RS07450 6567ee676edd31e56089d01ca78d2398 351 Gene3D G3DSA:3.65.10.20 10 182 8.9E-86 T 11-11-2016 IPR023797 RNA 3'-terminal phosphate cyclase domain AUP74_RS07450 6567ee676edd31e56089d01ca78d2398 351 Gene3D G3DSA:3.65.10.20 282 339 8.9E-86 T 11-11-2016 IPR023797 RNA 3'-terminal phosphate cyclase domain AUP74_RS07450 6567ee676edd31e56089d01ca78d2398 351 TIGRFAM TIGR03399 RNA_3prim_cycl: RNA 3'-phosphate cyclase 11 335 1.0E-122 T 11-11-2016 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 AUP74_RS07450 6567ee676edd31e56089d01ca78d2398 351 PIRSF PIRSF005378 6 347 2.6E-114 T 11-11-2016 IPR000228 RNA 3'-terminal phosphate cyclase GO:0006396 AUP74_RS07450 6567ee676edd31e56089d01ca78d2398 351 Gene3D G3DSA:3.30.360.20 191 280 4.1E-15 T 11-11-2016 IPR013791 RNA 3'-terminal phosphate cyclase, insert domain AUP74_RS06605 efb2163bb44a2ed016b882b08e2ffe05 261 SUPERFAMILY SSF53613 5 259 7.09E-46 T 11-11-2016 IPR029056 Ribokinase-like AUP74_RS06605 efb2163bb44a2ed016b882b08e2ffe05 261 Pfam PF08543 Phosphomethylpyrimidine kinase 15 249 1.2E-50 T 11-11-2016 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-964975 AUP74_RS06605 efb2163bb44a2ed016b882b08e2ffe05 261 Gene3D G3DSA:3.40.1190.20 6 255 4.2E-54 T 11-11-2016 IPR029056 Ribokinase-like AUP74_RS01335 f9f448e2961bf2fc05cb826efae92690 336 SUPERFAMILY SSF46689 284 333 3.72E-10 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS01335 f9f448e2961bf2fc05cb826efae92690 336 SMART SM00342 248 330 5.4E-19 T 11-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AUP74_RS01335 f9f448e2961bf2fc05cb826efae92690 336 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 23 206 9.8E-37 T 11-11-2016 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal AUP74_RS01335 f9f448e2961bf2fc05cb826efae92690 336 Pfam PF12833 Helix-turn-helix domain 255 332 2.3E-15 T 11-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AUP74_RS01335 f9f448e2961bf2fc05cb826efae92690 336 Gene3D G3DSA:1.10.10.60 283 334 9.5E-12 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS15070 5907662d9dfa820556b37463f0a210ec 749 Pfam PF10070 Uncharacterized protein conserved in bacteria (DUF2309) 5 725 2.6E-213 T 11-11-2016 IPR018752 Uncharacterised protein family UPF0753 AUP74_RS15070 5907662d9dfa820556b37463f0a210ec 749 Hamap MF_01871 UPF0753 protein . 1 740 20.748 T 11-11-2016 IPR018752 Uncharacterised protein family UPF0753 AUP74_RS06970 f4fedc55f4f6902e7a91a0aec819bfd8 484 Pfam PF03283 Pectinacetylesterase 181 278 1.0E-12 T 11-11-2016 IPR004963 Pectinacetylesterase/NOTUM GO:0016787 Reactome: R-HSA-5362798 AUP74_RS11950 b6a8c34b936626e213ca06f871b47832 78 Pfam PF04400 Protein of unknown function (DUF539) 22 66 4.0E-14 T 11-11-2016 IPR007495 (Na+)-NQR maturation factor NqrM AUP74_RS05675 bafc1311481786314ab948212abe8283 194 Pfam PF02622 Uncharacterized ACR, COG1678 24 181 9.2E-46 T 11-11-2016 IPR003774 Protein of unknown function UPF0301 AUP74_RS05675 bafc1311481786314ab948212abe8283 194 SUPERFAMILY SSF143456 14 194 1.3E-57 T 11-11-2016 AUP74_RS05675 bafc1311481786314ab948212abe8283 194 Gene3D G3DSA:3.30.70.1300 54 137 2.6E-24 T 11-11-2016 AUP74_RS05675 bafc1311481786314ab948212abe8283 194 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 13 194 35.86 T 11-11-2016 IPR003774 Protein of unknown function UPF0301 AUP74_RS05675 bafc1311481786314ab948212abe8283 194 Gene3D G3DSA:3.40.1740.10 11 52 1.7E-31 T 11-11-2016 AUP74_RS05675 bafc1311481786314ab948212abe8283 194 Gene3D G3DSA:3.40.1740.10 138 184 1.7E-31 T 11-11-2016 AUP74_RS01605 07c35b04cde2d298fd493b2e082cbaab 143 Pfam PF11964 SpoIIAA-like 22 125 8.2E-17 T 11-11-2016 IPR021866 SpoIIAA-like AUP74_RS01605 07c35b04cde2d298fd493b2e082cbaab 143 Gene3D G3DSA:3.40.50.10600 4 126 1.1E-38 T 11-11-2016 IPR021866 SpoIIAA-like AUP74_RS01605 07c35b04cde2d298fd493b2e082cbaab 143 SUPERFAMILY SSF52091 6 125 6.67E-35 T 11-11-2016 IPR002645 STAS domain AUP74_RS09365 6476a2d73f77192a18ffa0dd450fc558 267 Pfam PF08241 Methyltransferase domain 87 172 4.0E-9 T 11-11-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 AUP74_RS09365 6476a2d73f77192a18ffa0dd450fc558 267 Gene3D G3DSA:3.40.50.150 66 197 6.5E-17 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS09365 6476a2d73f77192a18ffa0dd450fc558 267 PIRSF PIRSF018249 1 266 1.9E-71 T 11-11-2016 IPR016718 rRNA (guanine-N1-)-methyltransferase A, predicted GO:0008168 AUP74_RS09365 6476a2d73f77192a18ffa0dd450fc558 267 SUPERFAMILY SSF53335 5 248 1.17E-37 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS11450 9a05203d91cf93df4bfdaab4dd8799b5 218 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 164 200 1.5E-7 T 11-11-2016 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AUP74_RS11450 9a05203d91cf93df4bfdaab4dd8799b5 218 PIRSF PIRSF000239 1 215 1.5E-73 T 11-11-2016 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AUP74_RS11450 9a05203d91cf93df4bfdaab4dd8799b5 218 Pfam PF00578 AhpC/TSA family 5 142 1.2E-29 T 11-11-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AUP74_RS11450 9a05203d91cf93df4bfdaab4dd8799b5 218 Gene3D G3DSA:3.30.1020.10 165 216 8.2E-21 T 11-11-2016 AUP74_RS11450 9a05203d91cf93df4bfdaab4dd8799b5 218 SUPERFAMILY SSF52833 3 214 4.49E-65 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS11450 9a05203d91cf93df4bfdaab4dd8799b5 218 Gene3D G3DSA:3.40.30.10 4 164 1.6E-57 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS08925 430fdc1cfe3bfb54601d41286ee3836d 305 Pfam PF04321 RmlD substrate binding domain 2 290 7.6E-97 T 11-11-2016 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581 AUP74_RS08925 430fdc1cfe3bfb54601d41286ee3836d 305 SUPERFAMILY SSF51735 2 290 5.76E-90 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS08925 430fdc1cfe3bfb54601d41286ee3836d 305 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 288 1.5E-94 T 11-11-2016 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581 AUP74_RS08925 430fdc1cfe3bfb54601d41286ee3836d 305 Gene3D G3DSA:3.40.50.720 2 231 8.0E-55 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS10715 02d988fb1624de269fc09cac6886a63c 416 Pfam PF00817 impB/mucB/samB family 4 147 1.7E-32 T 11-11-2016 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 AUP74_RS10715 02d988fb1624de269fc09cac6886a63c 416 Pfam PF11799 impB/mucB/samB family C-terminal domain 240 351 5.6E-7 T 11-11-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 AUP74_RS10715 02d988fb1624de269fc09cac6886a63c 416 Gene3D G3DSA:1.10.150.20 168 235 4.9E-18 T 11-11-2016 AUP74_RS10715 02d988fb1624de269fc09cac6886a63c 416 Pfam PF13438 Domain of unknown function (DUF4113) 364 413 2.1E-15 T 11-11-2016 IPR025188 Domain of unknown function DUF4113 AUP74_RS10715 02d988fb1624de269fc09cac6886a63c 416 Gene3D G3DSA:3.30.70.270 66 152 2.1E-18 T 11-11-2016 AUP74_RS10715 02d988fb1624de269fc09cac6886a63c 416 SUPERFAMILY SSF56672 1 233 4.54E-64 T 11-11-2016 AUP74_RS07150 1d90394172764ef9dfe4e9e398b30a17 152 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 6 26 - T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS07150 1d90394172764ef9dfe4e9e398b30a17 152 Gene3D G3DSA:3.30.700.10 8 77 2.0E-17 T 11-11-2016 AUP74_RS07150 1d90394172764ef9dfe4e9e398b30a17 152 PRINTS PR00813 Bacterial general secretion pathway protein G signature 43 61 2.9E-8 T 11-11-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 AUP74_RS07150 1d90394172764ef9dfe4e9e398b30a17 152 PRINTS PR00813 Bacterial general secretion pathway protein G signature 7 32 2.9E-8 T 11-11-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 AUP74_RS07150 1d90394172764ef9dfe4e9e398b30a17 152 Pfam PF16732 Type IV minor pilin ComP, DNA uptake sequence receptor 29 118 8.6E-22 T 11-11-2016 IPR031982 Type IV minor pilin ComP AUP74_RS07150 1d90394172764ef9dfe4e9e398b30a17 152 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 3 27 1.9E-9 T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS07150 1d90394172764ef9dfe4e9e398b30a17 152 SUPERFAMILY SSF54523 8 141 7.85E-23 T 11-11-2016 AUP74_RS07150 1d90394172764ef9dfe4e9e398b30a17 152 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 27 4.1E-10 T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS10635 b3dc73bc659c382e5f95e58a3fab6c59 480 SUPERFAMILY SSF53474 292 344 4.5E-21 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS10635 b3dc73bc659c382e5f95e58a3fab6c59 480 SUPERFAMILY SSF53474 115 228 4.5E-21 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS10635 b3dc73bc659c382e5f95e58a3fab6c59 480 Pfam PF12146 Serine aminopeptidase, S33 114 240 2.6E-14 T 11-11-2016 IPR022742 Serine aminopeptidase, S33 AUP74_RS10635 b3dc73bc659c382e5f95e58a3fab6c59 480 Gene3D G3DSA:3.40.50.1820 114 351 3.0E-23 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS01970 907fd84fb568577f536ad9ae4d150fe7 465 Pfam PF01235 Sodium:alanine symporter family 61 457 3.0E-116 T 11-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AUP74_RS01970 907fd84fb568577f536ad9ae4d150fe7 465 TIGRFAM TIGR00835 agcS: amino acid carrier protein 19 452 1.6E-117 T 11-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AUP74_RS01970 907fd84fb568577f536ad9ae4d150fe7 465 PRINTS PR00175 Sodium/alanine symporter signature 362 384 2.0E-34 T 11-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AUP74_RS01970 907fd84fb568577f536ad9ae4d150fe7 465 PRINTS PR00175 Sodium/alanine symporter signature 225 244 2.0E-34 T 11-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AUP74_RS01970 907fd84fb568577f536ad9ae4d150fe7 465 PRINTS PR00175 Sodium/alanine symporter signature 421 441 2.0E-34 T 11-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AUP74_RS01970 907fd84fb568577f536ad9ae4d150fe7 465 PRINTS PR00175 Sodium/alanine symporter signature 95 117 2.0E-34 T 11-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AUP74_RS01970 907fd84fb568577f536ad9ae4d150fe7 465 PRINTS PR00175 Sodium/alanine symporter signature 316 334 2.0E-34 T 11-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AUP74_RS01970 907fd84fb568577f536ad9ae4d150fe7 465 PRINTS PR00175 Sodium/alanine symporter signature 197 215 2.0E-34 T 11-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AUP74_RS01970 907fd84fb568577f536ad9ae4d150fe7 465 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 95 110 - T 11-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AUP74_RS16165 4acd42fb125f16dd1f13590d812cbd1d 150 SUPERFAMILY SSF53254 2 129 2.75E-20 T 11-11-2016 IPR029033 Histidine phosphatase superfamily AUP74_RS16165 4acd42fb125f16dd1f13590d812cbd1d 150 Gene3D G3DSA:3.40.50.1240 2 147 4.7E-28 T 11-11-2016 IPR029033 Histidine phosphatase superfamily AUP74_RS16165 4acd42fb125f16dd1f13590d812cbd1d 150 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 77 4.1E-12 T 11-11-2016 IPR013078 Histidine phosphatase superfamily, clade-1 AUP74_RS16165 4acd42fb125f16dd1f13590d812cbd1d 150 SMART SM00855 2 110 8.5E-7 T 11-11-2016 IPR013078 Histidine phosphatase superfamily, clade-1 AUP74_RS02375 6503ae527364050478b846f4aedeba65 181 SUPERFAMILY SSF55166 54 181 9.68E-33 T 11-11-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 AUP74_RS02375 6503ae527364050478b846f4aedeba65 181 Pfam PF05951 Bacterial protein of unknown function (DUF882) 35 181 4.1E-61 T 11-11-2016 IPR010275 Protein of unknown function DUF882 AUP74_RS02375 6503ae527364050478b846f4aedeba65 181 Gene3D G3DSA:3.30.1380.10 66 181 4.6E-29 T 11-11-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 AUP74_RS11305 50880e73cce45ec9bace6e07c795f380 146 Pfam PF04143 Sulphur transport 50 133 7.4E-7 T 11-11-2016 IPR007272 Sulphur transport domain AUP74_RS08395 d2cdfb1e758b89b0cabd83a3f6d485a7 896 Gene3D G3DSA:2.170.130.10 64 174 1.4E-17 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS08395 d2cdfb1e758b89b0cabd83a3f6d485a7 896 Pfam PF00593 TonB dependent receptor 628 894 3.5E-29 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS08395 d2cdfb1e758b89b0cabd83a3f6d485a7 896 Gene3D G3DSA:2.40.170.20 350 398 1.3E-66 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS08395 d2cdfb1e758b89b0cabd83a3f6d485a7 896 Gene3D G3DSA:2.40.170.20 175 317 1.3E-66 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS08395 d2cdfb1e758b89b0cabd83a3f6d485a7 896 Gene3D G3DSA:2.40.170.20 561 896 1.3E-66 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS08395 d2cdfb1e758b89b0cabd83a3f6d485a7 896 Gene3D G3DSA:2.40.170.20 436 513 1.3E-66 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS08395 d2cdfb1e758b89b0cabd83a3f6d485a7 896 SUPERFAMILY SSF56935 555 896 3.43E-95 T 11-11-2016 AUP74_RS08395 d2cdfb1e758b89b0cabd83a3f6d485a7 896 SUPERFAMILY SSF56935 349 499 3.43E-95 T 11-11-2016 AUP74_RS08395 d2cdfb1e758b89b0cabd83a3f6d485a7 896 SUPERFAMILY SSF56935 33 237 3.43E-95 T 11-11-2016 AUP74_RS08395 d2cdfb1e758b89b0cabd83a3f6d485a7 896 SUPERFAMILY SSF56935 271 322 3.43E-95 T 11-11-2016 AUP74_RS08395 d2cdfb1e758b89b0cabd83a3f6d485a7 896 Pfam PF07715 TonB-dependent Receptor Plug Domain 64 171 2.3E-13 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS08395 d2cdfb1e758b89b0cabd83a3f6d485a7 896 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 43 888 1.9E-181 T 11-11-2016 IPR010104 Bacterial TonB-dependent receptor AUP74_RS16000 70933f738130ecdefb4209ad746e9a0c 620 SUPERFAMILY SSF52096 470 531 6.59E-38 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS16000 70933f738130ecdefb4209ad746e9a0c 620 SUPERFAMILY SSF52096 325 441 6.59E-38 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS16000 70933f738130ecdefb4209ad746e9a0c 620 Pfam PF01343 Peptidase family S49 393 544 1.0E-45 T 11-11-2016 IPR002142 Peptidase S49 GO:0006508|GO:0008233 AUP74_RS16000 70933f738130ecdefb4209ad746e9a0c 620 Pfam PF01343 Peptidase family S49 137 294 4.3E-30 T 11-11-2016 IPR002142 Peptidase S49 GO:0006508|GO:0008233 AUP74_RS16000 70933f738130ecdefb4209ad746e9a0c 620 TIGRFAM TIGR00705 SppA_67K: signal peptide peptidase SppA, 67K type 24 612 3.3E-161 T 11-11-2016 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 AUP74_RS16000 70933f738130ecdefb4209ad746e9a0c 620 PIRSF PIRSF001217 11 620 7.6E-185 T 11-11-2016 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 AUP74_RS16000 70933f738130ecdefb4209ad746e9a0c 620 Gene3D G3DSA:3.90.226.10 471 548 1.1E-53 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS16000 70933f738130ecdefb4209ad746e9a0c 620 Gene3D G3DSA:3.90.226.10 216 313 5.4E-55 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS16000 70933f738130ecdefb4209ad746e9a0c 620 Gene3D G3DSA:3.90.226.10 35 173 5.4E-55 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS16000 70933f738130ecdefb4209ad746e9a0c 620 Gene3D G3DSA:3.90.226.10 324 433 1.1E-53 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS16000 70933f738130ecdefb4209ad746e9a0c 620 SUPERFAMILY SSF52096 92 177 2.98E-22 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS16000 70933f738130ecdefb4209ad746e9a0c 620 SUPERFAMILY SSF52096 208 283 2.98E-22 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS13035 9a31a6047823a82e9088de1e69eed3ad 336 Gene3D G3DSA:3.40.50.300 10 172 9.7E-51 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS13035 9a31a6047823a82e9088de1e69eed3ad 336 Pfam PF09115 DNA polymerase III, delta subunit, C terminal 213 331 3.6E-5 T 11-11-2016 IPR015199 DNA polymerase III, delta subunit, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS13035 9a31a6047823a82e9088de1e69eed3ad 336 Pfam PF13177 DNA polymerase III, delta subunit 13 171 1.8E-42 T 11-11-2016 AUP74_RS13035 9a31a6047823a82e9088de1e69eed3ad 336 SUPERFAMILY SSF52540 10 211 1.39E-47 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS13035 9a31a6047823a82e9088de1e69eed3ad 336 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 18 206 3.9E-63 T 11-11-2016 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AUP74_RS03660 b9c3cbbddbbf8218935e8cd2b948317e 636 Pfam PF05960 Bacterial protein of unknown function (DUF885) 79 626 2.1E-171 T 11-11-2016 IPR010281 Protein of unknown function DUF885 AUP74_RS04710 5148a8fbb0fa723b074ce284e93ef8b2 261 Pfam PF02104 SURF1 family 30 233 1.3E-22 T 11-11-2016 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS04660 ced23fa1d7c9e7a818e422cf5d698a7b 674 Pfam PF01432 Peptidase family M3 218 671 1.9E-151 T 11-11-2016 IPR001567 Peptidase M3A/M3B GO:0004222|GO:0006508 AUP74_RS04660 ced23fa1d7c9e7a818e422cf5d698a7b 674 Gene3D G3DSA:3.40.390.10 354 498 4.4E-56 T 11-11-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 AUP74_RS04660 ced23fa1d7c9e7a818e422cf5d698a7b 674 SUPERFAMILY SSF55486 1 671 3.57E-189 T 11-11-2016 AUP74_RS04660 ced23fa1d7c9e7a818e422cf5d698a7b 674 Gene3D G3DSA:1.10.1370.10 499 673 8.0E-138 T 11-11-2016 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 AUP74_RS04660 ced23fa1d7c9e7a818e422cf5d698a7b 674 Gene3D G3DSA:1.10.1370.10 137 345 8.0E-138 T 11-11-2016 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 AUP74_RS04660 ced23fa1d7c9e7a818e422cf5d698a7b 674 Gene3D G3DSA:1.20.1050.40 12 133 4.6E-11 T 11-11-2016 IPR024080 Neurolysin/Thimet oligopeptidase, N-terminal AUP74_RS14890 da4658d718f2820c161721588129d422 429 Pfam PF07396 Phosphate-selective porin O and P 47 415 1.0E-39 T 11-11-2016 IPR010870 Phosphate-selective porin O/P AUP74_RS14890 da4658d718f2820c161721588129d422 429 Gene3D G3DSA:2.40.160.10 29 429 6.5E-83 T 11-11-2016 IPR023614 Porin domain AUP74_RS14890 da4658d718f2820c161721588129d422 429 SUPERFAMILY SSF56935 41 228 5.19E-22 T 11-11-2016 AUP74_RS14890 da4658d718f2820c161721588129d422 429 SUPERFAMILY SSF56935 265 428 5.19E-22 T 11-11-2016 AUP74_RS13665 396716ac17d083242c23d50bd8440f5a 504 Pfam PF13091 PLD-like domain 63 211 2.8E-20 T 11-11-2016 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 AUP74_RS13665 396716ac17d083242c23d50bd8440f5a 504 Pfam PF13091 PLD-like domain 305 446 2.1E-19 T 11-11-2016 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 AUP74_RS13665 396716ac17d083242c23d50bd8440f5a 504 SUPERFAMILY SSF56024 21 221 2.49E-40 T 11-11-2016 AUP74_RS13665 396716ac17d083242c23d50bd8440f5a 504 SUPERFAMILY SSF56024 272 453 6.28E-29 T 11-11-2016 AUP74_RS13665 396716ac17d083242c23d50bd8440f5a 504 Gene3D G3DSA:3.30.870.10 301 488 3.5E-35 T 11-11-2016 AUP74_RS13665 396716ac17d083242c23d50bd8440f5a 504 Gene3D G3DSA:3.30.870.10 43 223 7.8E-36 T 11-11-2016 AUP74_RS13665 396716ac17d083242c23d50bd8440f5a 504 SMART SM00155 153 180 0.022 T 11-11-2016 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 AUP74_RS13665 396716ac17d083242c23d50bd8440f5a 504 SMART SM00155 393 420 0.002 T 11-11-2016 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 AUP74_RS08705 266d2e8e6296538799d336ceeb51489d 303 Gene3D G3DSA:3.90.550.10 5 282 3.5E-67 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases AUP74_RS08705 266d2e8e6296538799d336ceeb51489d 303 SUPERFAMILY SSF53448 5 285 7.21E-61 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases AUP74_RS08705 266d2e8e6296538799d336ceeb51489d 303 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 273 6.0E-112 T 11-11-2016 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343 AUP74_RS08705 266d2e8e6296538799d336ceeb51489d 303 Pfam PF00483 Nucleotidyl transferase 6 273 8.5E-25 T 11-11-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 AUP74_RS14950 af7162f2223090287a006f2f3b1f07ed 475 ProSitePatterns PS00163 Fumarate lyases signature. 321 330 - T 11-11-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 AUP74_RS14950 af7162f2223090287a006f2f3b1f07ed 475 Gene3D G3DSA:1.20.200.10 144 422 1.1E-85 T 11-11-2016 AUP74_RS14950 af7162f2223090287a006f2f3b1f07ed 475 Pfam PF00206 Lyase 15 346 2.5E-100 T 11-11-2016 IPR022761 Fumarate lyase, N-terminal AUP74_RS14950 af7162f2223090287a006f2f3b1f07ed 475 SUPERFAMILY SSF48557 7 467 2.21E-138 T 11-11-2016 IPR008948 L-Aspartase-like GO:0003824 AUP74_RS14950 af7162f2223090287a006f2f3b1f07ed 475 Gene3D G3DSA:1.10.40.30 423 468 1.5E-19 T 11-11-2016 AUP74_RS14950 af7162f2223090287a006f2f3b1f07ed 475 Pfam PF10415 Fumarase C C-terminus 412 464 9.9E-19 T 11-11-2016 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AUP74_RS14950 af7162f2223090287a006f2f3b1f07ed 475 PRINTS PR00149 Fumarate lyase superfamily signature 184 202 1.6E-27 T 11-11-2016 IPR000362 Fumarate lyase family AUP74_RS14950 af7162f2223090287a006f2f3b1f07ed 475 PRINTS PR00149 Fumarate lyase superfamily signature 139 157 1.6E-27 T 11-11-2016 IPR000362 Fumarate lyase family AUP74_RS14950 af7162f2223090287a006f2f3b1f07ed 475 PRINTS PR00149 Fumarate lyase superfamily signature 275 302 1.6E-27 T 11-11-2016 IPR000362 Fumarate lyase family AUP74_RS14950 af7162f2223090287a006f2f3b1f07ed 475 PRINTS PR00149 Fumarate lyase superfamily signature 321 337 1.6E-27 T 11-11-2016 IPR000362 Fumarate lyase family AUP74_RS14950 af7162f2223090287a006f2f3b1f07ed 475 Gene3D G3DSA:1.10.275.10 7 143 2.8E-56 T 11-11-2016 IPR024083 Fumarase/histidase, N-terminal AUP74_RS06450 eb30cd38feb0c861e991089f0319079e 290 SUPERFAMILY SSF81324 22 237 8.63E-33 T 11-11-2016 AUP74_RS06450 eb30cd38feb0c861e991089f0319079e 290 Gene3D G3DSA:1.20.120.350 21 132 1.3E-12 T 11-11-2016 IPR027359 Voltage-dependent channel, four helix bundle domain AUP74_RS06450 eb30cd38feb0c861e991089f0319079e 290 Pfam PF00520 Ion transport protein 23 241 5.6E-49 T 11-11-2016 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 AUP74_RS04215 1dd14bcb21b5d30b195f2ad841b904e6 192 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 29 162 5.5E-21 T 11-11-2016 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component AUP74_RS09995 b061dbd90825aab3b9eb55368f4c4815 203 Gene3D G3DSA:3.90.79.10 26 185 5.4E-37 T 11-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 AUP74_RS09995 b061dbd90825aab3b9eb55368f4c4815 203 SUPERFAMILY SSF55811 21 183 7.18E-31 T 11-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 AUP74_RS09995 b061dbd90825aab3b9eb55368f4c4815 203 Pfam PF00293 NUDIX domain 29 138 1.3E-13 T 11-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 AUP74_RS06580 08afc28832600c1d76fbf45f10293f90 197 Gene3D G3DSA:3.40.50.360 2 190 3.4E-37 T 11-11-2016 IPR029039 Flavoprotein-like domain AUP74_RS06580 08afc28832600c1d76fbf45f10293f90 197 Pfam PF02525 Flavodoxin-like fold 3 182 3.4E-32 T 11-11-2016 IPR003680 Flavodoxin-like fold AUP74_RS06580 08afc28832600c1d76fbf45f10293f90 197 SUPERFAMILY SSF52218 2 181 2.39E-35 T 11-11-2016 IPR029039 Flavoprotein-like domain AUP74_RS05030 8eb5da7cd9eb3dff781f09e756b83094 149 Pfam PF08660 Oligosaccharide biosynthesis protein Alg14 like 58 146 1.2E-7 T 11-11-2016 IPR013969 Oligosaccharide biosynthesis protein Alg14-like Reactome: R-HSA-446193|Reactome: R-HSA-5633231 AUP74_RS05030 8eb5da7cd9eb3dff781f09e756b83094 149 Gene3D G3DSA:3.40.50.2000 2 139 7.5E-6 T 11-11-2016 AUP74_RS05030 8eb5da7cd9eb3dff781f09e756b83094 149 SUPERFAMILY SSF53756 11 114 4.08E-5 T 11-11-2016 AUP74_RS09210 669253a82295af89b0eb7244106cac64 167 PRINTS PR00421 Thioredoxin family signature 130 141 6.2E-5 T 11-11-2016 AUP74_RS09210 669253a82295af89b0eb7244106cac64 167 PRINTS PR00421 Thioredoxin family signature 63 71 6.2E-5 T 11-11-2016 AUP74_RS09210 669253a82295af89b0eb7244106cac64 167 PRINTS PR00421 Thioredoxin family signature 71 80 6.2E-5 T 11-11-2016 AUP74_RS09210 669253a82295af89b0eb7244106cac64 167 Pfam PF08534 Redoxin 47 154 8.0E-11 T 11-11-2016 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 AUP74_RS09210 669253a82295af89b0eb7244106cac64 167 SUPERFAMILY SSF52833 36 159 2.05E-26 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS09210 669253a82295af89b0eb7244106cac64 167 Gene3D G3DSA:3.40.30.10 13 155 4.1E-26 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS09210 669253a82295af89b0eb7244106cac64 167 ProSitePatterns PS00194 Thioredoxin family active site. 64 82 - T 11-11-2016 IPR017937 Thioredoxin, conserved site GO:0045454 AUP74_RS00270 432164e9128fdd2b3e97208fa191b83c 486 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 186 482 1.2E-110 T 11-11-2016 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AUP74_RS00270 432164e9128fdd2b3e97208fa191b83c 486 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 164 192 1.4E-47 T 11-11-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AUP74_RS00270 432164e9128fdd2b3e97208fa191b83c 486 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 234 250 1.4E-47 T 11-11-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AUP74_RS00270 432164e9128fdd2b3e97208fa191b83c 486 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 324 350 1.4E-47 T 11-11-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AUP74_RS00270 432164e9128fdd2b3e97208fa191b83c 486 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 140 153 1.4E-47 T 11-11-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AUP74_RS00270 432164e9128fdd2b3e97208fa191b83c 486 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 216 233 1.4E-47 T 11-11-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AUP74_RS00270 432164e9128fdd2b3e97208fa191b83c 486 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 174 180 - T 11-11-2016 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AUP74_RS00270 432164e9128fdd2b3e97208fa191b83c 486 PIRSF PIRSF000110 1 486 3.3E-159 T 11-11-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AUP74_RS00270 432164e9128fdd2b3e97208fa191b83c 486 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 8 184 1.4E-49 T 11-11-2016 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AUP74_RS00270 432164e9128fdd2b3e97208fa191b83c 486 SUPERFAMILY SSF51735 2 187 8.86E-47 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS00270 432164e9128fdd2b3e97208fa191b83c 486 Gene3D G3DSA:3.40.50.720 3 183 1.3E-52 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS00270 432164e9128fdd2b3e97208fa191b83c 486 SUPERFAMILY SSF55347 174 483 4.58E-107 T 11-11-2016 AUP74_RS00270 432164e9128fdd2b3e97208fa191b83c 486 Gene3D G3DSA:3.30.360.10 184 483 1.6E-117 T 11-11-2016 AUP74_RS00270 432164e9128fdd2b3e97208fa191b83c 486 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 5 484 7.6E-163 T 11-11-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AUP74_RS00270 432164e9128fdd2b3e97208fa191b83c 486 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 4 484 77.582 T 11-11-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AUP74_RS16155 e273e4092fdb644f1ad6725a28675536 114 SUPERFAMILY SSF55331 2 112 1.41E-25 T 11-11-2016 IPR014347 Tautomerase/MIF superfamily AUP74_RS16155 e273e4092fdb644f1ad6725a28675536 114 Gene3D G3DSA:3.30.429.10 1 112 9.5E-30 T 11-11-2016 AUP74_RS11985 307b98e1d6e9418b7a8b474f92b7199e 291 Gene3D G3DSA:3.40.50.1820 5 285 8.3E-71 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS11985 307b98e1d6e9418b7a8b474f92b7199e 291 PRINTS PR00111 Alpha/beta hydrolase fold signature 116 129 1.8E-7 T 11-11-2016 IPR000073 Alpha/beta hydrolase fold-1 AUP74_RS11985 307b98e1d6e9418b7a8b474f92b7199e 291 PRINTS PR00111 Alpha/beta hydrolase fold signature 56 71 1.8E-7 T 11-11-2016 IPR000073 Alpha/beta hydrolase fold-1 AUP74_RS11985 307b98e1d6e9418b7a8b474f92b7199e 291 PRINTS PR00111 Alpha/beta hydrolase fold signature 102 115 1.8E-7 T 11-11-2016 IPR000073 Alpha/beta hydrolase fold-1 AUP74_RS11985 307b98e1d6e9418b7a8b474f92b7199e 291 SUPERFAMILY SSF53474 4 280 8.77E-47 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS11985 307b98e1d6e9418b7a8b474f92b7199e 291 Pfam PF00561 alpha/beta hydrolase fold 31 137 1.5E-18 T 11-11-2016 IPR000073 Alpha/beta hydrolase fold-1 AUP74_RS12880 dce333459599bb898bb95f4a00b4c38d 725 SUPERFAMILY SSF51645 2 722 0.0 T 11-11-2016 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 AUP74_RS12880 dce333459599bb898bb95f4a00b4c38d 725 Gene3D G3DSA:1.20.1220.12 590 723 1.2E-76 T 11-11-2016 AUP74_RS12880 dce333459599bb898bb95f4a00b4c38d 725 Gene3D G3DSA:1.10.1860.10 1 88 7.1E-35 T 11-11-2016 AUP74_RS12880 dce333459599bb898bb95f4a00b4c38d 725 Pfam PF01274 Malate synthase 18 697 2.0E-187 T 11-11-2016 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 AUP74_RS12880 dce333459599bb898bb95f4a00b4c38d 725 Gene3D G3DSA:3.20.20.360 89 135 1.6E-151 T 11-11-2016 AUP74_RS12880 dce333459599bb898bb95f4a00b4c38d 725 Gene3D G3DSA:3.20.20.360 266 296 1.6E-151 T 11-11-2016 AUP74_RS12880 dce333459599bb898bb95f4a00b4c38d 725 Gene3D G3DSA:3.20.20.360 336 588 1.6E-151 T 11-11-2016 AUP74_RS12880 dce333459599bb898bb95f4a00b4c38d 725 TIGRFAM TIGR01345 malate_syn_G: malate synthase G 4 722 0.0 T 11-11-2016 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 AUP74_RS12880 dce333459599bb898bb95f4a00b4c38d 725 Gene3D G3DSA:2.170.170.11 298 335 4.4E-65 T 11-11-2016 IPR023310 Malate synthase G, beta sub-domain GO:0004474 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 AUP74_RS12880 dce333459599bb898bb95f4a00b4c38d 725 Gene3D G3DSA:2.170.170.11 136 264 4.4E-65 T 11-11-2016 IPR023310 Malate synthase G, beta sub-domain GO:0004474 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 AUP74_RS12880 dce333459599bb898bb95f4a00b4c38d 725 Hamap MF_00641 Malate synthase G [glcB]. 1 725 402.944 T 11-11-2016 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 AUP74_RS09905 a4e9f3c490c2fa618a93f48603297d9d 377 SUPERFAMILY SSF56317 63 103 2.09E-21 T 11-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AUP74_RS09905 a4e9f3c490c2fa618a93f48603297d9d 377 SUPERFAMILY SSF56317 143 274 2.09E-21 T 11-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AUP74_RS09905 a4e9f3c490c2fa618a93f48603297d9d 377 Gene3D G3DSA:3.60.110.10 70 100 5.7E-24 T 11-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AUP74_RS09905 a4e9f3c490c2fa618a93f48603297d9d 377 Gene3D G3DSA:3.60.110.10 144 275 5.7E-24 T 11-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AUP74_RS09905 a4e9f3c490c2fa618a93f48603297d9d 377 Pfam PF00795 Carbon-nitrogen hydrolase 123 280 2.7E-10 T 11-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AUP74_RS07390 50fa167694ee03f4e094cb9761999e7b 72 Gene3D G3DSA:1.20.1070.10 12 68 6.5E-4 T 11-11-2016 AUP74_RS03140 6dfb1ce6a50b1cb75900f171f5dc2492 315 SUPERFAMILY SSF53474 50 310 1.79E-56 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS03140 6dfb1ce6a50b1cb75900f171f5dc2492 315 Pfam PF07859 alpha/beta hydrolase fold 85 289 4.1E-53 T 11-11-2016 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 AUP74_RS03140 6dfb1ce6a50b1cb75900f171f5dc2492 315 Gene3D G3DSA:3.40.50.1820 3 311 2.1E-73 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS14780 69f834791c64bd9062232fa84c9d70a5 397 SUPERFAMILY SSF48452 112 290 3.29E-12 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS14780 69f834791c64bd9062232fa84c9d70a5 397 Pfam PF13432 Tetratricopeptide repeat 115 170 0.016 T 11-11-2016 AUP74_RS14780 69f834791c64bd9062232fa84c9d70a5 397 Gene3D G3DSA:1.25.40.10 192 322 2.1E-13 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS14780 69f834791c64bd9062232fa84c9d70a5 397 SUPERFAMILY SSF48452 42 142 3.52E-6 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS14780 69f834791c64bd9062232fa84c9d70a5 397 Hamap MF_00994 Lipopolysaccharide assembly protein B [lapB]. 5 395 33.786 T 11-11-2016 IPR030865 Lipopolysaccharide assembly protein B GO:0008653 AUP74_RS14780 69f834791c64bd9062232fa84c9d70a5 397 Pfam PF14559 Tetratricopeptide repeat 199 264 1.7E-8 T 11-11-2016 AUP74_RS14780 69f834791c64bd9062232fa84c9d70a5 397 Gene3D G3DSA:1.25.40.10 43 167 4.3E-10 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS14780 69f834791c64bd9062232fa84c9d70a5 397 SMART SM00028 223 256 31.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS14780 69f834791c64bd9062232fa84c9d70a5 397 SMART SM00028 73 106 51.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS14780 69f834791c64bd9062232fa84c9d70a5 397 SMART SM00028 189 222 73.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS02255 8848122ee11ec2b4913bd4c7eff1f03f 591 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 404 418 - T 11-11-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 AUP74_RS02255 8848122ee11ec2b4913bd4c7eff1f03f 591 SUPERFAMILY SSF160246 15 163 7.85E-12 T 11-11-2016 AUP74_RS02255 8848122ee11ec2b4913bd4c7eff1f03f 591 SMART SM00382 337 458 4.6E-4 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS02255 8848122ee11ec2b4913bd4c7eff1f03f 591 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 66 167 9.6E-14 T 11-11-2016 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 AUP74_RS02255 8848122ee11ec2b4913bd4c7eff1f03f 591 Gene3D G3DSA:3.40.50.300 317 585 4.0E-90 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS02255 8848122ee11ec2b4913bd4c7eff1f03f 591 Pfam PF00437 Type II/IV secretion system protein 212 476 1.6E-74 T 11-11-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 AUP74_RS02255 8848122ee11ec2b4913bd4c7eff1f03f 591 SUPERFAMILY SSF52540 194 583 2.17E-98 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS02255 8848122ee11ec2b4913bd4c7eff1f03f 591 Gene3D G3DSA:3.30.450.90 189 309 1.4E-46 T 11-11-2016 AUP74_RS09040 198bf1f2d465e69cce6b66c03c369f4d 351 Pfam PF12069 Protein of unknown function (DUF3549) 5 342 1.7E-80 T 11-11-2016 IPR021936 Protein of unknown function DUF3549 AUP74_RS14080 d3e2d943b27d42c83fa7fa3d39ea16d9 467 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 253 291 - T 11-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AUP74_RS14080 d3e2d943b27d42c83fa7fa3d39ea16d9 467 Gene3D G3DSA:3.40.640.10 65 343 1.8E-79 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AUP74_RS14080 d3e2d943b27d42c83fa7fa3d39ea16d9 467 Pfam PF00202 Aminotransferase class-III 30 445 1.7E-95 T 11-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AUP74_RS14080 d3e2d943b27d42c83fa7fa3d39ea16d9 467 SUPERFAMILY SSF53383 1 447 1.36E-114 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase AUP74_RS14080 d3e2d943b27d42c83fa7fa3d39ea16d9 467 Gene3D G3DSA:3.90.1150.10 5 64 3.4E-37 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS14080 d3e2d943b27d42c83fa7fa3d39ea16d9 467 Gene3D G3DSA:3.90.1150.10 345 448 3.4E-37 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 AUP74_RS14360 90e97291597a59d8fe416eeaff8bbe67 391 SUPERFAMILY SSF55961 107 329 8.51E-21 T 11-11-2016 AUP74_RS14360 90e97291597a59d8fe416eeaff8bbe67 391 Gene3D G3DSA:2.102.10.10 4 118 2.0E-34 T 11-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AUP74_RS14360 90e97291597a59d8fe416eeaff8bbe67 391 SUPERFAMILY SSF50022 2 115 9.17E-33 T 11-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AUP74_RS14360 90e97291597a59d8fe416eeaff8bbe67 391 Pfam PF00355 Rieske [2Fe-2S] domain 6 86 1.6E-19 T 11-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AUP74_RS03890 7ca4614f4e5fb40e8c14b1fcd2ab9c07 155 PIRSF PIRSF016548 1 155 1.0E-55 T 11-11-2016 IPR007448 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ GO:0006355 AUP74_RS03890 7ca4614f4e5fb40e8c14b1fcd2ab9c07 155 Pfam PF04353 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ 1 147 2.6E-54 T 11-11-2016 IPR007448 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ GO:0006355 AUP74_RS00740 6ca84e7345fcb5f5e4695f64a02c7661 323 PIRSF PIRSF026649 1 306 5.2E-105 T 11-11-2016 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 AUP74_RS00740 6ca84e7345fcb5f5e4695f64a02c7661 323 TIGRFAM TIGR02207 lipid_A_htrB: lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase 4 306 3.3E-123 T 11-11-2016 IPR011920 Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase GO:0009245|GO:0016021|GO:0016740 KEGG: 00600+2.3.1.24 AUP74_RS00740 6ca84e7345fcb5f5e4695f64a02c7661 323 Hamap MF_01942 Lipid A biosynthesis lauroyltransferase [lpxL]. 3 306 48.1 T 11-11-2016 IPR011920 Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase GO:0009245|GO:0016021|GO:0016740 KEGG: 00600+2.3.1.24 AUP74_RS00740 6ca84e7345fcb5f5e4695f64a02c7661 323 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 4 297 2.0E-85 T 11-11-2016 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 AUP74_RS00765 7f9759978f4a649aef1c6423572ed550 392 Pfam PF07055 Enoyl reductase FAD binding domain 320 383 3.6E-28 T 11-11-2016 IPR024906 Enoyl reductase FAD binding domain KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 AUP74_RS00765 7f9759978f4a649aef1c6423572ed550 392 Pfam PF12241 Trans-2-enoyl-CoA reductase catalytic region 82 314 1.9E-110 T 11-11-2016 IPR024910 Trans-2-enoyl-CoA reductase catalytic domain, putative KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 AUP74_RS00765 7f9759978f4a649aef1c6423572ed550 392 Pfam PF12242 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2 80 2.8E-39 T 11-11-2016 IPR010758 Trans-2-enoyl-CoA reductase GO:0016491|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 AUP74_RS00765 7f9759978f4a649aef1c6423572ed550 392 Gene3D G3DSA:3.40.50.720 42 143 4.8E-4 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS00765 7f9759978f4a649aef1c6423572ed550 392 Hamap MF_01838 Trans-2-enoyl-CoA reductase [NADH] [fabV]. 1 389 54.539 T 11-11-2016 IPR010758 Trans-2-enoyl-CoA reductase GO:0016491|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 AUP74_RS11125 0bda4f6a7ca5f8c4a4bf1f3b1248c3a4 353 Pfam PF05128 Domain of unknown function (DUF697) 188 347 5.9E-32 T 11-11-2016 IPR021147 Protein of unknown function DUF697 AUP74_RS00855 821f78c59f40f85adc3b040beaccd238 367 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 19 342 21.113 T 11-11-2016 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AUP74_RS00855 821f78c59f40f85adc3b040beaccd238 367 Pfam PF01259 SAICAR synthetase 22 293 1.5E-45 T 11-11-2016 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AUP74_RS00855 821f78c59f40f85adc3b040beaccd238 367 Gene3D G3DSA:3.30.200.20 13 135 1.4E-31 T 11-11-2016 AUP74_RS00855 821f78c59f40f85adc3b040beaccd238 367 SUPERFAMILY SSF56104 13 344 4.25E-66 T 11-11-2016 AUP74_RS00855 821f78c59f40f85adc3b040beaccd238 367 Gene3D G3DSA:3.30.470.20 136 282 1.2E-38 T 11-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 AUP74_RS00855 821f78c59f40f85adc3b040beaccd238 367 TIGRFAM TIGR02735 purC_vibrio: phosphoribosylaminoimidazole-succinocarboxamide synthase 2 366 3.1E-209 T 11-11-2016 IPR014106 Phosphoribosylaminoimidazole-succinocarboxamide synthase, Vibrio-type GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 AUP74_RS03195 93ef27c6a78060e2f7f436102640c148 86 TIGRFAM TIGR02181 GRX_bact: glutaredoxin 3 4 82 7.4E-36 T 11-11-2016 IPR011900 Glutaredoxin, GrxC GO:0045454 AUP74_RS03195 93ef27c6a78060e2f7f436102640c148 86 Gene3D G3DSA:3.40.30.10 2 86 2.9E-30 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS03195 93ef27c6a78060e2f7f436102640c148 86 ProSitePatterns PS00195 Glutaredoxin active site. 6 22 - T 11-11-2016 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 AUP74_RS03195 93ef27c6a78060e2f7f436102640c148 86 PRINTS PR00160 Glutaredoxin signature 4 22 2.0E-14 T 11-11-2016 IPR014025 Glutaredoxin subgroup AUP74_RS03195 93ef27c6a78060e2f7f436102640c148 86 PRINTS PR00160 Glutaredoxin signature 60 73 2.0E-14 T 11-11-2016 IPR014025 Glutaredoxin subgroup AUP74_RS03195 93ef27c6a78060e2f7f436102640c148 86 PRINTS PR00160 Glutaredoxin signature 46 59 2.0E-14 T 11-11-2016 IPR014025 Glutaredoxin subgroup AUP74_RS03195 93ef27c6a78060e2f7f436102640c148 86 SUPERFAMILY SSF52833 1 84 6.92E-30 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS03195 93ef27c6a78060e2f7f436102640c148 86 Pfam PF00462 Glutaredoxin 4 63 2.4E-21 T 11-11-2016 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 AUP74_RS02770 23ec4e3d68b504e0e8f8bccebb825e45 305 SUPERFAMILY SSF53850 101 301 2.35E-26 T 11-11-2016 AUP74_RS02770 23ec4e3d68b504e0e8f8bccebb825e45 305 Pfam PF03466 LysR substrate binding domain 102 301 3.1E-25 T 11-11-2016 IPR005119 LysR, substrate-binding AUP74_RS02770 23ec4e3d68b504e0e8f8bccebb825e45 305 SUPERFAMILY SSF46785 14 116 1.26E-13 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS02770 23ec4e3d68b504e0e8f8bccebb825e45 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 16 77 4.4E-12 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS02770 23ec4e3d68b504e0e8f8bccebb825e45 305 Gene3D G3DSA:3.40.190.10 104 207 8.1E-14 T 11-11-2016 AUP74_RS02770 23ec4e3d68b504e0e8f8bccebb825e45 305 Gene3D G3DSA:3.40.190.10 228 272 6.9E-5 T 11-11-2016 AUP74_RS02770 23ec4e3d68b504e0e8f8bccebb825e45 305 Gene3D G3DSA:1.10.10.10 13 96 1.8E-16 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS09895 b8ae9e54e71182013067fc19eb530e4d 456 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 35 450 1.1E-122 T 11-11-2016 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 AUP74_RS09895 b8ae9e54e71182013067fc19eb530e4d 456 Pfam PF06965 Na+/H+ antiporter 1 34 451 4.2E-145 T 11-11-2016 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 AUP74_RS09895 b8ae9e54e71182013067fc19eb530e4d 456 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 32 456 22.635 T 11-11-2016 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 AUP74_RS09895 b8ae9e54e71182013067fc19eb530e4d 456 Gene3D G3DSA:1.20.1530.10 317 453 3.8E-146 T 11-11-2016 IPR023171 Na/H antiporter domain AUP74_RS09895 b8ae9e54e71182013067fc19eb530e4d 456 Gene3D G3DSA:1.20.1530.10 31 271 3.8E-146 T 11-11-2016 IPR023171 Na/H antiporter domain AUP74_RS07910 109d0feb908a2c1e48e8b6acb1b11cc3 143 Gene3D G3DSA:4.10.520.10 46 142 1.5E-18 T 11-11-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 AUP74_RS07910 109d0feb908a2c1e48e8b6acb1b11cc3 143 SMART SM00411 45 142 2.1E-8 T 11-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 AUP74_RS07910 109d0feb908a2c1e48e8b6acb1b11cc3 143 Pfam PF00216 Bacterial DNA-binding protein 46 140 8.0E-19 T 11-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 AUP74_RS07910 109d0feb908a2c1e48e8b6acb1b11cc3 143 SUPERFAMILY SSF47729 46 142 1.91E-16 T 11-11-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 AUP74_RS13385 3b5b1ed3c506cf532ff37d88f09da805 209 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 44 198 1.3E-66 T 11-11-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AUP74_RS13385 3b5b1ed3c506cf532ff37d88f09da805 209 Pfam PF01625 Peptide methionine sulfoxide reductase 46 198 1.9E-66 T 11-11-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AUP74_RS13385 3b5b1ed3c506cf532ff37d88f09da805 209 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 43 204 38.337 T 11-11-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AUP74_RS13385 3b5b1ed3c506cf532ff37d88f09da805 209 SUPERFAMILY SSF55068 4 206 1.83E-81 T 11-11-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AUP74_RS13385 3b5b1ed3c506cf532ff37d88f09da805 209 Gene3D G3DSA:3.30.1060.10 6 198 3.7E-81 T 11-11-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AUP74_RS16435 0d573fb3f6bcf532e8150bbdb78def07 222 Pfam PF03352 Methyladenine glycosylase 50 137 1.2E-14 T 11-11-2016 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 AUP74_RS16435 0d573fb3f6bcf532e8150bbdb78def07 222 Gene3D G3DSA:1.10.340.30 39 138 5.2E-21 T 11-11-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AUP74_RS16435 0d573fb3f6bcf532e8150bbdb78def07 222 SUPERFAMILY SSF48150 37 171 1.73E-29 T 11-11-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AUP74_RS11635 ec999bda955354cf3d484f985107b018 341 Pfam PF05175 Methyltransferase small domain 168 334 7.7E-40 T 11-11-2016 IPR007848 Methyltransferase small domain GO:0008168 AUP74_RS11635 ec999bda955354cf3d484f985107b018 341 SUPERFAMILY SSF53335 183 336 6.55E-26 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS11635 ec999bda955354cf3d484f985107b018 341 Gene3D G3DSA:3.40.50.150 190 331 1.2E-19 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS07895 14ade36cebc6f8b1df8ea48bc9faa03d 356 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 301 346 - T 11-11-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AUP74_RS07895 14ade36cebc6f8b1df8ea48bc9faa03d 356 Pfam PF12833 Helix-turn-helix domain 269 351 1.9E-14 T 11-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AUP74_RS07895 14ade36cebc6f8b1df8ea48bc9faa03d 356 SUPERFAMILY SSF46689 301 352 4.17E-9 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS07895 14ade36cebc6f8b1df8ea48bc9faa03d 356 Gene3D G3DSA:1.10.10.60 300 353 2.0E-13 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS07895 14ade36cebc6f8b1df8ea48bc9faa03d 356 SMART SM00342 263 350 8.3E-13 T 11-11-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AUP74_RS04740 1fb3d2823096c1b44438a7c9b825ce38 268 Pfam PF02517 CAAX protease self-immunity 165 256 6.1E-12 T 11-11-2016 IPR003675 CAAX amino terminal protease GO:0016020 AUP74_RS02075 a508dfe1eea59bb0958ccf57a47b2adc 478 PIRSF PIRSF011396 1 478 9.9E-193 T 11-11-2016 IPR006905 Tryptophan halogenase AUP74_RS02075 a508dfe1eea59bb0958ccf57a47b2adc 478 SUPERFAMILY SSF51905 304 415 5.65E-26 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS02075 a508dfe1eea59bb0958ccf57a47b2adc 478 SUPERFAMILY SSF51905 2 71 5.65E-26 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS02075 a508dfe1eea59bb0958ccf57a47b2adc 478 SUPERFAMILY SSF51905 121 219 5.65E-26 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS02075 a508dfe1eea59bb0958ccf57a47b2adc 478 Pfam PF04820 Tryptophan halogenase 1 444 2.5E-174 T 11-11-2016 IPR006905 Tryptophan halogenase AUP74_RS02075 a508dfe1eea59bb0958ccf57a47b2adc 478 Gene3D G3DSA:3.50.50.60 1 56 1.2E-39 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS02075 a508dfe1eea59bb0958ccf57a47b2adc 478 Gene3D G3DSA:3.50.50.60 299 343 1.2E-39 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS02075 a508dfe1eea59bb0958ccf57a47b2adc 478 Gene3D G3DSA:3.50.50.60 137 217 1.2E-39 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS02790 1f37dc39fe4bef369b8c83430ef9d9f1 173 Gene3D G3DSA:3.40.630.30 68 171 6.9E-15 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS02790 1f37dc39fe4bef369b8c83430ef9d9f1 173 Pfam PF13673 Acetyltransferase (GNAT) domain 68 171 6.2E-6 T 11-11-2016 IPR000182 GNAT domain GO:0008080 AUP74_RS02790 1f37dc39fe4bef369b8c83430ef9d9f1 173 SUPERFAMILY SSF55729 40 171 8.41E-19 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS09030 5c233c23d3a9a17bf72d751f85ed2ec7 215 Pfam PF01914 MarC family integral membrane protein 7 204 2.1E-15 T 11-11-2016 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 AUP74_RS12125 7f163b7bdbeecb3886b5f784c0160a24 188 SUPERFAMILY SSF55961 40 188 4.32E-17 T 11-11-2016 AUP74_RS12125 7f163b7bdbeecb3886b5f784c0160a24 188 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 52 151 1.4E-7 T 11-11-2016 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 AUP74_RS12125 7f163b7bdbeecb3886b5f784c0160a24 188 Gene3D G3DSA:3.30.530.20 39 188 6.6E-16 T 11-11-2016 IPR023393 START-like domain AUP74_RS15195 a9d131817b33b98ecfafec59851a80eb 178 Pfam PF09831 Uncharacterized protein conserved in bacteria (DUF2058) 3 178 8.7E-66 T 11-11-2016 IPR018636 Protein of unknown function DUF2058 AUP74_RS15435 3fbf0ebb5625970e43e7a25017a0f806 81 Gene3D G3DSA:1.10.150.250 2 75 2.6E-26 T 11-11-2016 IPR005631 Flavinator of succinate dehydrogenase AUP74_RS15435 3fbf0ebb5625970e43e7a25017a0f806 81 Pfam PF03937 Flavinator of succinate dehydrogenase 3 73 3.1E-24 T 11-11-2016 IPR005631 Flavinator of succinate dehydrogenase AUP74_RS15435 3fbf0ebb5625970e43e7a25017a0f806 81 SUPERFAMILY SSF109910 2 75 1.2E-23 T 11-11-2016 IPR005631 Flavinator of succinate dehydrogenase AUP74_RS00115 c0a2f404ea2b5ed6411bfb0a65abc35d 279 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 12 248 2.7E-32 T 11-11-2016 AUP74_RS01720 f6623d3424bbf7fbb45939dff65461f6 345 Gene3D G3DSA:3.40.50.1820 53 336 7.2E-35 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS01720 f6623d3424bbf7fbb45939dff65461f6 345 Pfam PF12740 Chlorophyllase enzyme 72 192 1.3E-11 T 11-11-2016 IPR017395 Chlorophyllase GO:0015996|GO:0047746 KEGG: 00860+3.1.1.14|MetaCyc: PWY-5098|MetaCyc: PWY-6927|MetaCyc: PWY-7164 AUP74_RS01720 f6623d3424bbf7fbb45939dff65461f6 345 SUPERFAMILY SSF53474 61 322 1.03E-29 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS12760 ad0f92e1c282acab093bb5323f216645 867 Pfam PF07715 TonB-dependent Receptor Plug Domain 52 159 4.1E-19 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS12760 ad0f92e1c282acab093bb5323f216645 867 SUPERFAMILY SSF56935 35 379 1.06E-108 T 11-11-2016 AUP74_RS12760 ad0f92e1c282acab093bb5323f216645 867 SUPERFAMILY SSF56935 595 867 1.06E-108 T 11-11-2016 AUP74_RS12760 ad0f92e1c282acab093bb5323f216645 867 SUPERFAMILY SSF56935 468 543 1.06E-108 T 11-11-2016 AUP74_RS12760 ad0f92e1c282acab093bb5323f216645 867 Gene3D G3DSA:2.40.170.20 487 538 7.4E-82 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS12760 ad0f92e1c282acab093bb5323f216645 867 Gene3D G3DSA:2.40.170.20 169 390 7.4E-82 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS12760 ad0f92e1c282acab093bb5323f216645 867 Gene3D G3DSA:2.40.170.20 587 867 7.4E-82 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS12760 ad0f92e1c282acab093bb5323f216645 867 Gene3D G3DSA:2.170.130.10 34 168 1.7E-36 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS08345 cf609603ed7fc77309cf04b21c483483 391 Gene3D G3DSA:1.20.1090.10 194 385 5.6E-54 T 11-11-2016 AUP74_RS08345 cf609603ed7fc77309cf04b21c483483 391 Gene3D G3DSA:3.40.50.1970 8 193 2.4E-54 T 11-11-2016 AUP74_RS08345 cf609603ed7fc77309cf04b21c483483 391 Pfam PF00465 Iron-containing alcohol dehydrogenase 13 375 3.2E-112 T 11-11-2016 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 AUP74_RS08345 cf609603ed7fc77309cf04b21c483483 391 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 182 210 - T 11-11-2016 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 AUP74_RS08345 cf609603ed7fc77309cf04b21c483483 391 SUPERFAMILY SSF56796 9 387 9.94E-120 T 11-11-2016 AUP74_RS06125 a3001e1584eeb6ba29bfe896c282942d 301 Pfam PF00682 HMGL-like 8 282 1.4E-58 T 11-11-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 AUP74_RS06125 a3001e1584eeb6ba29bfe896c282942d 301 Gene3D G3DSA:3.20.20.70 7 293 3.2E-91 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS06125 a3001e1584eeb6ba29bfe896c282942d 301 SUPERFAMILY SSF51569 5 296 3.81E-75 T 11-11-2016 AUP74_RS11955 f5125cbd013ccdbc6e616e4243ca49e8 465 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 325 6.4E-61 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS11955 f5125cbd013ccdbc6e616e4243ca49e8 465 Gene3D G3DSA:3.50.50.60 143 334 2.2E-46 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS11955 f5125cbd013ccdbc6e616e4243ca49e8 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 138 156 2.4E-28 T 11-11-2016 AUP74_RS11955 f5125cbd013ccdbc6e616e4243ca49e8 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 177 195 2.4E-28 T 11-11-2016 AUP74_RS11955 f5125cbd013ccdbc6e616e4243ca49e8 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 277 2.4E-28 T 11-11-2016 AUP74_RS11955 f5125cbd013ccdbc6e616e4243ca49e8 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 2.4E-28 T 11-11-2016 AUP74_RS11955 f5125cbd013ccdbc6e616e4243ca49e8 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 290 312 2.4E-28 T 11-11-2016 AUP74_RS11955 f5125cbd013ccdbc6e616e4243ca49e8 465 Gene3D G3DSA:3.30.390.30 343 457 6.0E-29 T 11-11-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AUP74_RS11955 f5125cbd013ccdbc6e616e4243ca49e8 465 SUPERFAMILY SSF55424 343 463 2.58E-27 T 11-11-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 AUP74_RS11955 f5125cbd013ccdbc6e616e4243ca49e8 465 Gene3D G3DSA:3.50.50.60 4 142 8.0E-32 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS11955 f5125cbd013ccdbc6e616e4243ca49e8 465 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 344 454 5.5E-26 T 11-11-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AUP74_RS11955 f5125cbd013ccdbc6e616e4243ca49e8 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 305 312 3.6E-52 T 11-11-2016 AUP74_RS11955 f5125cbd013ccdbc6e616e4243ca49e8 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 339 360 3.6E-52 T 11-11-2016 AUP74_RS11955 f5125cbd013ccdbc6e616e4243ca49e8 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 3.6E-52 T 11-11-2016 AUP74_RS11955 f5125cbd013ccdbc6e616e4243ca49e8 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 177 202 3.6E-52 T 11-11-2016 AUP74_RS11955 f5125cbd013ccdbc6e616e4243ca49e8 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 141 150 3.6E-52 T 11-11-2016 AUP74_RS11955 f5125cbd013ccdbc6e616e4243ca49e8 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 429 449 3.6E-52 T 11-11-2016 AUP74_RS11955 f5125cbd013ccdbc6e616e4243ca49e8 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 262 276 3.6E-52 T 11-11-2016 AUP74_RS11955 f5125cbd013ccdbc6e616e4243ca49e8 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 40 55 3.6E-52 T 11-11-2016 AUP74_RS11955 f5125cbd013ccdbc6e616e4243ca49e8 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 404 419 3.6E-52 T 11-11-2016 AUP74_RS11955 f5125cbd013ccdbc6e616e4243ca49e8 465 PIRSF PIRSF000350 1 465 1.8E-67 T 11-11-2016 AUP74_RS11955 f5125cbd013ccdbc6e616e4243ca49e8 465 SUPERFAMILY SSF51905 1 322 4.44E-55 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS02890 9b734c4d380d3eff689f2dee5087c83d 261 Gene3D G3DSA:3.40.50.1820 5 137 9.9E-37 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS02890 9b734c4d380d3eff689f2dee5087c83d 261 Gene3D G3DSA:3.40.50.1820 180 251 9.9E-37 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS02890 9b734c4d380d3eff689f2dee5087c83d 261 Pfam PF12146 Serine aminopeptidase, S33 48 138 6.6E-13 T 11-11-2016 IPR022742 Serine aminopeptidase, S33 AUP74_RS02890 9b734c4d380d3eff689f2dee5087c83d 261 SUPERFAMILY SSF53474 5 139 2.22E-41 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS02890 9b734c4d380d3eff689f2dee5087c83d 261 SUPERFAMILY SSF53474 182 252 2.22E-41 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS02150 911c9d3324b687fe670cdc494a2b1e85 267 SUPERFAMILY SSF56300 11 253 3.95E-50 T 11-11-2016 IPR029052 Metallo-dependent phosphatase-like AUP74_RS02150 911c9d3324b687fe670cdc494a2b1e85 267 Pfam PF00149 Calcineurin-like phosphoesterase 10 198 1.0E-14 T 11-11-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 AUP74_RS02150 911c9d3324b687fe670cdc494a2b1e85 267 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 10 253 35.454 T 11-11-2016 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 AUP74_RS02150 911c9d3324b687fe670cdc494a2b1e85 267 Gene3D G3DSA:3.60.21.10 8 251 7.9E-34 T 11-11-2016 IPR029052 Metallo-dependent phosphatase-like AUP74_RS02150 911c9d3324b687fe670cdc494a2b1e85 267 ProDom PD587589 PHOSPHODIESTERASE ICC METALLOPHOSPHOESTERASE CYCLIC REGULATOR LACZ AMP HYDROLASE 3'5'-CYCLIC-NUCLEOTIDE EXPRESSION 198 253 5.0E-11 T 11-11-2016 IPR013622 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA, C-terminal KEGG: 00230+3.1.4.53 AUP74_RS04955 8e143629f51fdf6f8519ba988ccc4e1d 219 Pfam PF07290 Protein of unknown function (DUF1449) 9 209 3.0E-53 T 11-11-2016 IPR010840 Protein of unknown function DUF1449 AUP74_RS00705 66fb10b637ba324db7457a36e21663aa 267 SUPERFAMILY SSF55486 90 259 5.86E-7 T 11-11-2016 AUP74_RS04075 3f7b3edcbe118aefe24672db292a4276 197 SUPERFAMILY SSF48498 79 189 1.44E-16 T 11-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AUP74_RS04075 3f7b3edcbe118aefe24672db292a4276 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 4.1E-13 T 11-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AUP74_RS04075 3f7b3edcbe118aefe24672db292a4276 197 Gene3D G3DSA:1.10.357.10 58 181 2.0E-14 T 11-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 AUP74_RS04075 3f7b3edcbe118aefe24672db292a4276 197 SUPERFAMILY SSF46689 4 80 1.54E-16 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS04075 3f7b3edcbe118aefe24672db292a4276 197 Gene3D G3DSA:1.10.10.60 3 57 8.0E-21 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS14690 ffe4da88d27ed4de77bfc048401718d7 349 Gene3D G3DSA:1.25.40.10 245 339 2.9E-7 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS14690 ffe4da88d27ed4de77bfc048401718d7 349 SUPERFAMILY SSF48452 251 338 2.74E-7 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS08795 35116cef26f7bf0f80c177c518da153d 247 SUPERFAMILY SSF48452 73 155 2.75E-6 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS08795 35116cef26f7bf0f80c177c518da153d 247 Gene3D G3DSA:1.25.40.10 71 182 3.1E-7 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS15460 f2c32c2235578339ca641b1baf7eae06 160 Gene3D G3DSA:3.30.70.860 94 160 1.3E-36 T 11-11-2016 AUP74_RS15460 f2c32c2235578339ca641b1baf7eae06 160 SUPERFAMILY SSF89963 2 86 1.28E-27 T 11-11-2016 IPR007551 Protein of unknown function DUF520 AUP74_RS15460 f2c32c2235578339ca641b1baf7eae06 160 Pfam PF04461 Protein of unknown function (DUF520) 2 159 3.2E-64 T 11-11-2016 IPR007551 Protein of unknown function DUF520 AUP74_RS15460 f2c32c2235578339ca641b1baf7eae06 160 Gene3D G3DSA:3.30.70.990 9 93 1.8E-27 T 11-11-2016 AUP74_RS15460 f2c32c2235578339ca641b1baf7eae06 160 SUPERFAMILY SSF89963 88 160 1.96E-31 T 11-11-2016 IPR007551 Protein of unknown function DUF520 AUP74_RS15460 f2c32c2235578339ca641b1baf7eae06 160 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 1 160 28.644 T 11-11-2016 IPR007551 Protein of unknown function DUF520 AUP74_RS14445 bef166ccefda81fef325df35b39abf52 265 Pfam PF00106 short chain dehydrogenase 3 192 5.0E-39 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS14445 bef166ccefda81fef325df35b39abf52 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 7.5E-19 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS14445 bef166ccefda81fef325df35b39abf52 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 7.5E-19 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS14445 bef166ccefda81fef325df35b39abf52 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 7.5E-19 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS14445 bef166ccefda81fef325df35b39abf52 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 7.5E-19 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS14445 bef166ccefda81fef325df35b39abf52 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 7.5E-19 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS14445 bef166ccefda81fef325df35b39abf52 265 Gene3D G3DSA:3.40.50.720 4 203 4.9E-48 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS14445 bef166ccefda81fef325df35b39abf52 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 5.2E-6 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS14445 bef166ccefda81fef325df35b39abf52 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 5.2E-6 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR AUP74_RS14445 bef166ccefda81fef325df35b39abf52 265 SUPERFAMILY SSF51735 3 204 7.35E-48 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS08480 5e4ab717d7c6ce7098ae02e92268cdb6 520 Pfam PF04820 Tryptophan halogenase 8 473 3.2E-113 T 11-11-2016 IPR006905 Tryptophan halogenase AUP74_RS08480 5e4ab717d7c6ce7098ae02e92268cdb6 520 Gene3D G3DSA:3.50.50.60 5 79 1.7E-53 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS08480 5e4ab717d7c6ce7098ae02e92268cdb6 520 Gene3D G3DSA:3.50.50.60 161 242 1.7E-53 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS08480 5e4ab717d7c6ce7098ae02e92268cdb6 520 Gene3D G3DSA:3.50.50.60 332 376 1.7E-53 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS08480 5e4ab717d7c6ce7098ae02e92268cdb6 520 PIRSF PIRSF011396 1 519 1.3E-157 T 11-11-2016 IPR006905 Tryptophan halogenase AUP74_RS08480 5e4ab717d7c6ce7098ae02e92268cdb6 520 SUPERFAMILY SSF51905 6 91 9.36E-34 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS08480 5e4ab717d7c6ce7098ae02e92268cdb6 520 SUPERFAMILY SSF51905 329 423 9.36E-34 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS08480 5e4ab717d7c6ce7098ae02e92268cdb6 520 SUPERFAMILY SSF51905 149 245 9.36E-34 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS15985 ddb88329fe4be1251540024fd46c0876 114 Pfam PF03960 ArsC family 5 112 5.7E-21 T 11-11-2016 IPR006660 Arsenate reductase-like AUP74_RS15985 ddb88329fe4be1251540024fd46c0876 114 Gene3D G3DSA:3.40.30.10 1 114 4.0E-53 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS15985 ddb88329fe4be1251540024fd46c0876 114 SUPERFAMILY SSF52833 1 114 1.65E-39 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS15985 ddb88329fe4be1251540024fd46c0876 114 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 3 114 2.7E-48 T 11-11-2016 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 AUP74_RS01975 3ba484481afd0a8d5a29ba53e5dba82f 506 SUPERFAMILY SSF103473 21 492 1.02E-36 T 11-11-2016 IPR020846 Major facilitator superfamily domain AUP74_RS01975 3ba484481afd0a8d5a29ba53e5dba82f 506 Pfam PF07690 Major Facilitator Superfamily 316 497 1.9E-11 T 11-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AUP74_RS01975 3ba484481afd0a8d5a29ba53e5dba82f 506 Pfam PF07690 Major Facilitator Superfamily 27 301 4.4E-17 T 11-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AUP74_RS01975 3ba484481afd0a8d5a29ba53e5dba82f 506 Gene3D G3DSA:1.20.1250.20 21 229 3.4E-20 T 11-11-2016 AUP74_RS01975 3ba484481afd0a8d5a29ba53e5dba82f 506 Gene3D G3DSA:1.20.1250.20 266 493 1.5E-18 T 11-11-2016 AUP74_RS06430 d8f77a08682cdec06dd1dae1283dcfc7 359 Gene3D G3DSA:3.90.1200.10 101 339 6.2E-65 T 11-11-2016 AUP74_RS06430 d8f77a08682cdec06dd1dae1283dcfc7 359 Pfam PF01636 Phosphotransferase enzyme family 32 244 1.7E-27 T 11-11-2016 IPR002575 Aminoglycoside phosphotransferase AUP74_RS06430 d8f77a08682cdec06dd1dae1283dcfc7 359 Gene3D G3DSA:3.30.200.20 10 99 5.2E-23 T 11-11-2016 AUP74_RS06430 d8f77a08682cdec06dd1dae1283dcfc7 359 SUPERFAMILY SSF56112 15 321 2.04E-47 T 11-11-2016 IPR011009 Protein kinase-like domain AUP74_RS08895 2e028022053bf13c512f537de488175b 305 Gene3D G3DSA:3.90.550.10 1 264 9.9E-67 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases AUP74_RS08895 2e028022053bf13c512f537de488175b 305 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 3 287 1.0E-146 T 11-11-2016 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 AUP74_RS08895 2e028022053bf13c512f537de488175b 305 SUPERFAMILY SSF53448 2 287 1.84E-87 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases AUP74_RS08895 2e028022053bf13c512f537de488175b 305 Pfam PF00483 Nucleotidyl transferase 3 239 1.0E-67 T 11-11-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 AUP74_RS14990 628d94380cb944ce05f3059e331af0d6 223 Gene3D G3DSA:1.20.120.530 82 217 4.0E-25 T 11-11-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal AUP74_RS14990 628d94380cb944ce05f3059e331af0d6 223 SMART SM00895 89 212 2.0E-18 T 11-11-2016 IPR011711 GntR, C-terminal AUP74_RS14990 628d94380cb944ce05f3059e331af0d6 223 SMART SM00345 21 79 2.5E-8 T 11-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AUP74_RS14990 628d94380cb944ce05f3059e331af0d6 223 Pfam PF07729 FCD domain 89 211 1.7E-23 T 11-11-2016 IPR011711 GntR, C-terminal AUP74_RS14990 628d94380cb944ce05f3059e331af0d6 223 SUPERFAMILY SSF46785 15 83 2.39E-14 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS14990 628d94380cb944ce05f3059e331af0d6 223 Gene3D G3DSA:1.10.10.10 6 79 8.1E-16 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS14990 628d94380cb944ce05f3059e331af0d6 223 SUPERFAMILY SSF48008 85 214 2.2E-26 T 11-11-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal AUP74_RS14990 628d94380cb944ce05f3059e331af0d6 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 79 4.0E-14 T 11-11-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AUP74_RS13865 c608b8a06f6402d1ade8fefcc5134dae 218 Gene3D G3DSA:1.20.58.320 19 106 1.2E-26 T 11-11-2016 AUP74_RS13865 c608b8a06f6402d1ade8fefcc5134dae 218 Pfam PF06041 Bacterial protein of unknown function (DUF924) 25 216 7.2E-60 T 11-11-2016 IPR010323 Protein of unknown function DUF924 AUP74_RS13865 c608b8a06f6402d1ade8fefcc5134dae 218 Gene3D G3DSA:1.25.40.10 108 216 2.6E-31 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS13865 c608b8a06f6402d1ade8fefcc5134dae 218 SUPERFAMILY SSF48452 19 215 1.67E-59 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS01905 6fa2c7674ef764f49ec91337789c83f2 344 Gene3D G3DSA:3.40.50.300 124 149 7.2E-4 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS01905 6fa2c7674ef764f49ec91337789c83f2 344 SUPERFAMILY SSF52821 1 46 1.51E-16 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS01905 6fa2c7674ef764f49ec91337789c83f2 344 SUPERFAMILY SSF52821 74 114 1.51E-16 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS01905 6fa2c7674ef764f49ec91337789c83f2 344 TIGRFAM TIGR03167 tRNA_sel_U_synt: tRNA 2-selenouridine synthase 1 325 1.5E-99 T 11-11-2016 IPR017582 tRNA 2-selenouridine synthase GO:0016785|GO:0043828|GO:0070329 AUP74_RS01905 6fa2c7674ef764f49ec91337789c83f2 344 Gene3D G3DSA:3.40.250.10 1 112 9.1E-26 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS01225 fcb3c0f3d0b4d9cc5caaef63a380f913 226 Gene3D G3DSA:1.10.10.60 17 62 4.7E-11 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS01225 fcb3c0f3d0b4d9cc5caaef63a380f913 226 Pfam PF00440 Bacterial regulatory proteins, tetR family 39 78 4.6E-8 T 11-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AUP74_RS01225 fcb3c0f3d0b4d9cc5caaef63a380f913 226 Gene3D G3DSA:1.10.357.10 63 126 1.5E-11 T 11-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 AUP74_RS01225 fcb3c0f3d0b4d9cc5caaef63a380f913 226 SUPERFAMILY SSF46689 19 89 4.46E-12 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS14140 17ce25ccd26f74236429c74c93759708 609 SUPERFAMILY SSF53187 67 345 4.3E-46 T 11-11-2016 AUP74_RS14140 17ce25ccd26f74236429c74c93759708 609 SMART SM00631 70 333 3.3E-4 T 11-11-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 AUP74_RS14140 17ce25ccd26f74236429c74c93759708 609 Gene3D G3DSA:3.40.630.10 57 349 3.2E-48 T 11-11-2016 AUP74_RS14140 17ce25ccd26f74236429c74c93759708 609 Pfam PF00246 Zinc carboxypeptidase 76 276 3.7E-25 T 11-11-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 AUP74_RS05765 51a087ecbb29acf2cc1c2ff946133d1a 472 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 150 459 4.0E-26 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS05765 51a087ecbb29acf2cc1c2ff946133d1a 472 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 28 135 1.7E-37 T 11-11-2016 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 AUP74_RS05765 51a087ecbb29acf2cc1c2ff946133d1a 472 Gene3D G3DSA:3.50.50.60 240 400 6.4E-49 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS05765 51a087ecbb29acf2cc1c2ff946133d1a 472 Gene3D G3DSA:1.10.1060.10 10 152 6.9E-45 T 11-11-2016 AUP74_RS05765 51a087ecbb29acf2cc1c2ff946133d1a 472 SUPERFAMILY SSF46548 10 160 3.14E-40 T 11-11-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 AUP74_RS05765 51a087ecbb29acf2cc1c2ff946133d1a 472 PRINTS PR00419 Adrenodoxin reductase family signature 174 187 1.1E-35 T 11-11-2016 AUP74_RS05765 51a087ecbb29acf2cc1c2ff946133d1a 472 PRINTS PR00419 Adrenodoxin reductase family signature 151 173 1.1E-35 T 11-11-2016 AUP74_RS05765 51a087ecbb29acf2cc1c2ff946133d1a 472 PRINTS PR00419 Adrenodoxin reductase family signature 216 226 1.1E-35 T 11-11-2016 AUP74_RS05765 51a087ecbb29acf2cc1c2ff946133d1a 472 PRINTS PR00419 Adrenodoxin reductase family signature 292 306 1.1E-35 T 11-11-2016 AUP74_RS05765 51a087ecbb29acf2cc1c2ff946133d1a 472 PRINTS PR00419 Adrenodoxin reductase family signature 326 339 1.1E-35 T 11-11-2016 AUP74_RS05765 51a087ecbb29acf2cc1c2ff946133d1a 472 Gene3D G3DSA:3.40.50.720 401 470 3.9E-34 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS05765 51a087ecbb29acf2cc1c2ff946133d1a 472 Gene3D G3DSA:3.40.50.720 153 239 3.9E-34 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS05765 51a087ecbb29acf2cc1c2ff946133d1a 472 SUPERFAMILY SSF51971 148 401 6.47E-71 T 11-11-2016 AUP74_RS05765 51a087ecbb29acf2cc1c2ff946133d1a 472 TIGRFAM TIGR01318 gltD_gamma_fam: glutamate synthase, small subunit 9 472 4.3E-239 T 11-11-2016 IPR006006 Glutamate synthase, NADH/NADPH, small subunit 2 GO:0006537|GO:0016639 AUP74_RS16490 6c26172e8a7c032cefe3090c30f62214 477 SUPERFAMILY SSF103365 7 477 4.05E-161 T 11-11-2016 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 AUP74_RS16490 6c26172e8a7c032cefe3090c30f62214 477 ProSitePatterns PS01288 Uncharacterized protein family UPF0027 signature. 46 75 - T 11-11-2016 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 AUP74_RS16490 6c26172e8a7c032cefe3090c30f62214 477 Pfam PF01139 tRNA-splicing ligase RtcB 46 477 1.3E-150 T 11-11-2016 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 AUP74_RS12450 0fb01cd5c986ed0daa3b8eb7983a6fd0 486 Pfam PF00361 Proton-conducting membrane transporter 130 423 1.9E-56 T 11-11-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS12450 0fb01cd5c986ed0daa3b8eb7983a6fd0 486 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 107 127 5.3E-20 T 11-11-2016 AUP74_RS12450 0fb01cd5c986ed0daa3b8eb7983a6fd0 486 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 240 266 5.3E-20 T 11-11-2016 AUP74_RS12450 0fb01cd5c986ed0daa3b8eb7983a6fd0 486 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 77 102 5.3E-20 T 11-11-2016 AUP74_RS12450 0fb01cd5c986ed0daa3b8eb7983a6fd0 486 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 218 239 5.3E-20 T 11-11-2016 AUP74_RS12450 0fb01cd5c986ed0daa3b8eb7983a6fd0 486 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 62 117 3.0E-8 T 11-11-2016 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS05965 a06ecebfab5debb95d9aa705090d9fa4 480 Gene3D G3DSA:1.10.860.10 20 122 1.1E-36 T 11-11-2016 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal AUP74_RS05965 a06ecebfab5debb95d9aa705090d9fa4 480 Gene3D G3DSA:3.40.50.300 182 473 1.0E-98 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05965 a06ecebfab5debb95d9aa705090d9fa4 480 SUPERFAMILY SSF48024 20 129 1.57E-36 T 11-11-2016 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 AUP74_RS05965 a06ecebfab5debb95d9aa705090d9fa4 480 Pfam PF00772 DnaB-like helicase N terminal domain 20 121 2.8E-34 T 11-11-2016 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 AUP74_RS05965 a06ecebfab5debb95d9aa705090d9fa4 480 Pfam PF03796 DnaB-like helicase C terminal domain 197 471 1.7E-104 T 11-11-2016 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 AUP74_RS05965 a06ecebfab5debb95d9aa705090d9fa4 480 SUPERFAMILY SSF52540 195 464 4.72E-47 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS05965 a06ecebfab5debb95d9aa705090d9fa4 480 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 21 473 1.2E-158 T 11-11-2016 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 AUP74_RS02850 fa50366c32b74e1e629e967db69ede2d 502 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 299 310 - T 11-11-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 AUP74_RS02850 fa50366c32b74e1e629e967db69ede2d 502 Gene3D G3DSA:3.40.605.10 26 284 7.0E-93 T 11-11-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 AUP74_RS02850 fa50366c32b74e1e629e967db69ede2d 502 Gene3D G3DSA:3.40.309.10 285 472 2.2E-74 T 11-11-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 AUP74_RS02850 fa50366c32b74e1e629e967db69ede2d 502 SUPERFAMILY SSF53720 14 500 2.75E-169 T 11-11-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 AUP74_RS02850 fa50366c32b74e1e629e967db69ede2d 502 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 271 278 - T 11-11-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 AUP74_RS02850 fa50366c32b74e1e629e967db69ede2d 502 Pfam PF00171 Aldehyde dehydrogenase family 38 496 4.8E-175 T 11-11-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 AUP74_RS03450 6227f8dc3f2640281044baf119c99a52 125 Pfam PF09996 Uncharacterized protein conserved in bacteria (DUF2237) 7 121 1.2E-51 T 11-11-2016 IPR018714 Protein of unknown function DUF2237 AUP74_RS07830 bd52a29727b1590bcf8bb7bc50128aa3 325 Pfam PF08349 Protein of unknown function (DUF1722) 200 313 3.3E-32 T 11-11-2016 IPR013560 Domain of unknown function DUF1722 AUP74_RS07830 bd52a29727b1590bcf8bb7bc50128aa3 325 Pfam PF04463 Protein of unknown function (DUF523) 12 156 3.9E-35 T 11-11-2016 IPR007553 Domain of unknown function DUF523 AUP74_RS03030 7235932d13cec70d44a96f42a5df3e04 376 SUPERFAMILY SSF111369 20 263 1.83E-26 T 11-11-2016 AUP74_RS03030 7235932d13cec70d44a96f42a5df3e04 376 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 22 336 3.0E-41 T 11-11-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 AUP74_RS03030 7235932d13cec70d44a96f42a5df3e04 376 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 27 246 7.6E-10 T 11-11-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AUP74_RS03030 7235932d13cec70d44a96f42a5df3e04 376 Gene3D G3DSA:2.40.50.100 31 65 3.7E-9 T 11-11-2016 AUP74_RS03030 7235932d13cec70d44a96f42a5df3e04 376 Gene3D G3DSA:2.40.50.100 141 172 3.7E-9 T 11-11-2016 AUP74_RS13515 fc0e31c482ee82ba92135c670ee8eb09 267 Gene3D G3DSA:3.90.226.10 4 264 3.1E-67 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS13515 fc0e31c482ee82ba92135c670ee8eb09 267 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 267 1.1E-48 T 11-11-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 AUP74_RS13515 fc0e31c482ee82ba92135c670ee8eb09 267 SUPERFAMILY SSF52096 3 265 1.08E-68 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS04285 97ab50abf4e73338a4809fc74c77a5cc 422 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 16 395 5.1E-77 T 11-11-2016 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 AUP74_RS04285 97ab50abf4e73338a4809fc74c77a5cc 422 ProSitePatterns PS00216 Sugar transport proteins signature 1. 70 86 - T 11-11-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AUP74_RS04285 97ab50abf4e73338a4809fc74c77a5cc 422 Pfam PF07690 Major Facilitator Superfamily 22 367 2.1E-42 T 11-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AUP74_RS04285 97ab50abf4e73338a4809fc74c77a5cc 422 SUPERFAMILY SSF103473 12 401 6.93E-58 T 11-11-2016 IPR020846 Major facilitator superfamily domain AUP74_RS04285 97ab50abf4e73338a4809fc74c77a5cc 422 Gene3D G3DSA:1.20.1250.20 15 195 3.3E-29 T 11-11-2016 AUP74_RS04285 97ab50abf4e73338a4809fc74c77a5cc 422 Gene3D G3DSA:1.20.1250.20 219 403 1.0E-6 T 11-11-2016 AUP74_RS16060 75ad4f2db222cbc946e632e754cbf00b 200 SUPERFAMILY SSF110997 124 189 1.96E-14 T 11-11-2016 IPR007730 Sporulation-related domain GO:0042834 AUP74_RS16060 75ad4f2db222cbc946e632e754cbf00b 200 Gene3D G3DSA:3.30.70.1070 123 198 1.3E-17 T 11-11-2016 IPR007730 Sporulation-related domain GO:0042834 AUP74_RS16060 75ad4f2db222cbc946e632e754cbf00b 200 Pfam PF05036 Sporulation related domain 124 187 1.6E-12 T 11-11-2016 IPR007730 Sporulation-related domain GO:0042834 AUP74_RS10170 c17f556434f70d6dfa570e6090e4440c 352 SUPERFAMILY SSF56112 16 330 7.42E-65 T 11-11-2016 IPR011009 Protein kinase-like domain AUP74_RS10170 c17f556434f70d6dfa570e6090e4440c 352 Gene3D G3DSA:3.90.1200.10 118 319 5.5E-33 T 11-11-2016 AUP74_RS10170 c17f556434f70d6dfa570e6090e4440c 352 Gene3D G3DSA:3.30.200.20 36 98 1.8E-4 T 11-11-2016 AUP74_RS10170 c17f556434f70d6dfa570e6090e4440c 352 Pfam PF01636 Phosphotransferase enzyme family 38 259 3.3E-57 T 11-11-2016 IPR002575 Aminoglycoside phosphotransferase AUP74_RS10810 2940660f0b5e4f131018b2c96af0f21f 344 SUPERFAMILY SSF56235 206 337 1.32E-101 T 11-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal AUP74_RS10810 2940660f0b5e4f131018b2c96af0f21f 344 SUPERFAMILY SSF56235 28 179 1.32E-101 T 11-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal AUP74_RS10810 2940660f0b5e4f131018b2c96af0f21f 344 Pfam PF01112 Asparaginase 29 336 5.2E-121 T 11-11-2016 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 AUP74_RS09745 ca05343d8c847c2ecfbcea66053ce0c1 306 Gene3D G3DSA:3.40.50.620 21 205 2.0E-21 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS09745 ca05343d8c847c2ecfbcea66053ce0c1 306 Pfam PF01171 PP-loop family 39 203 1.1E-13 T 11-11-2016 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 AUP74_RS09745 ca05343d8c847c2ecfbcea66053ce0c1 306 Hamap MF_01850 tRNA 2-thiocytidine biosynthesis protein TtcA [ttcA]. 8 269 58.267 T 11-11-2016 IPR012089 2-thiocytidine tRNA biosynthesis protein, TtcA GO:0008033 Reactome: R-HSA-6782315 AUP74_RS09745 ca05343d8c847c2ecfbcea66053ce0c1 306 PIRSF PIRSF004976 1 271 4.7E-73 T 11-11-2016 IPR012089 2-thiocytidine tRNA biosynthesis protein, TtcA GO:0008033 Reactome: R-HSA-6782315 AUP74_RS09745 ca05343d8c847c2ecfbcea66053ce0c1 306 SUPERFAMILY SSF52402 15 234 1.5E-56 T 11-11-2016 AUP74_RS08695 be7b0e29145504ca6c9388be70b2c615 409 Pfam PF16448 LapD/MoxY periplasmic domain 31 153 3.2E-31 T 11-11-2016 IPR032244 LapD/MoxY, periplasmic domain AUP74_RS15295 07f23092e44799b827c6d56bc6e51da6 297 SUPERFAMILY SSF48179 164 289 9.52E-42 T 11-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 AUP74_RS15295 07f23092e44799b827c6d56bc6e51da6 297 PIRSF PIRSF000103 1 295 2.5E-72 T 11-11-2016 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 AUP74_RS15295 07f23092e44799b827c6d56bc6e51da6 297 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 166 283 2.3E-35 T 11-11-2016 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 AUP74_RS15295 07f23092e44799b827c6d56bc6e51da6 297 Gene3D G3DSA:1.10.1040.10 166 286 1.9E-42 T 11-11-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AUP74_RS15295 07f23092e44799b827c6d56bc6e51da6 297 SUPERFAMILY SSF51735 3 165 3.05E-48 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS15295 07f23092e44799b827c6d56bc6e51da6 297 Gene3D G3DSA:3.40.50.720 2 163 1.9E-48 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS15295 07f23092e44799b827c6d56bc6e51da6 297 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 160 3.5E-44 T 11-11-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 AUP74_RS10205 068d74b4954027a99d3eb952285ce353 360 SUPERFAMILY SSF56672 1 234 1.78E-93 T 11-11-2016 AUP74_RS10205 068d74b4954027a99d3eb952285ce353 360 SUPERFAMILY SSF100879 241 338 3.73E-20 T 11-11-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 AUP74_RS10205 068d74b4954027a99d3eb952285ce353 360 Pfam PF00817 impB/mucB/samB family 7 154 5.5E-53 T 11-11-2016 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 AUP74_RS10205 068d74b4954027a99d3eb952285ce353 360 Gene3D G3DSA:3.30.1490.100 239 350 4.4E-30 T 11-11-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 AUP74_RS10205 068d74b4954027a99d3eb952285ce353 360 Hamap MF_01113 DNA polymerase IV [dinB]. 1 350 37.713 T 11-11-2016 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 AUP74_RS10205 068d74b4954027a99d3eb952285ce353 360 Gene3D G3DSA:3.30.70.270 66 164 3.8E-35 T 11-11-2016 AUP74_RS10205 068d74b4954027a99d3eb952285ce353 360 Gene3D G3DSA:1.10.150.20 165 235 4.9E-26 T 11-11-2016 AUP74_RS10205 068d74b4954027a99d3eb952285ce353 360 Pfam PF11799 impB/mucB/samB family C-terminal domain 237 334 7.1E-5 T 11-11-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 AUP74_RS00815 9869e75610081b0c92f6cc7f3ac773de 90 Gene3D G3DSA:4.10.490.10 33 89 1.7E-18 T 11-11-2016 IPR000170 High potential iron-sulphur protein GO:0009055|GO:0019646 AUP74_RS00815 9869e75610081b0c92f6cc7f3ac773de 90 SUPERFAMILY SSF57652 30 88 6.02E-16 T 11-11-2016 IPR000170 High potential iron-sulphur protein GO:0009055|GO:0019646 AUP74_RS00815 9869e75610081b0c92f6cc7f3ac773de 90 Pfam PF01355 High potential iron-sulfur protein 46 85 7.6E-7 T 11-11-2016 IPR000170 High potential iron-sulphur protein GO:0009055|GO:0019646 AUP74_RS14315 59022e32e3392164b1517fb492014f4d 469 Pfam PF03209 PUCC protein 327 450 1.4E-8 T 11-11-2016 IPR004896 PucC-related AUP74_RS14315 59022e32e3392164b1517fb492014f4d 469 Pfam PF03209 PUCC protein 30 306 1.5E-36 T 11-11-2016 IPR004896 PucC-related AUP74_RS14315 59022e32e3392164b1517fb492014f4d 469 SUPERFAMILY SSF103473 23 447 5.1E-21 T 11-11-2016 IPR020846 Major facilitator superfamily domain AUP74_RS14315 59022e32e3392164b1517fb492014f4d 469 Gene3D G3DSA:1.20.1250.20 239 447 2.6E-5 T 11-11-2016 AUP74_RS14315 59022e32e3392164b1517fb492014f4d 469 Gene3D G3DSA:1.20.1250.20 38 194 4.1E-5 T 11-11-2016 AUP74_RS13335 0105f85ca1b9ab737ac0fbf0242152d1 389 Pfam PF00999 Sodium/hydrogen exchanger family 13 370 1.1E-45 T 11-11-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 AUP74_RS03085 07ab02a28919129fe28c14d77a72d32c 409 Gene3D G3DSA:2.30.40.10 6 75 4.1E-14 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS03085 07ab02a28919129fe28c14d77a72d32c 409 Gene3D G3DSA:2.30.40.10 352 385 4.0E-5 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS03085 07ab02a28919129fe28c14d77a72d32c 409 SUPERFAMILY SSF51556 67 361 1.63E-87 T 11-11-2016 IPR032466 Metal-dependent hydrolase AUP74_RS03085 07ab02a28919129fe28c14d77a72d32c 409 SUPERFAMILY SSF51338 5 67 3.04E-27 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS03085 07ab02a28919129fe28c14d77a72d32c 409 SUPERFAMILY SSF51338 368 406 3.04E-27 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS03085 07ab02a28919129fe28c14d77a72d32c 409 TIGRFAM TIGR01224 hutI: imidazolonepropionase 29 403 3.3E-146 T 11-11-2016 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AUP74_RS03085 07ab02a28919129fe28c14d77a72d32c 409 Gene3D G3DSA:3.20.20.140 76 351 4.4E-42 T 11-11-2016 AUP74_RS03085 07ab02a28919129fe28c14d77a72d32c 409 Hamap MF_00372 Imidazolonepropionase [hutI]. 6 406 42.155 T 11-11-2016 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AUP74_RS03085 07ab02a28919129fe28c14d77a72d32c 409 Pfam PF01979 Amidohydrolase family 65 380 4.2E-21 T 11-11-2016 IPR006680 Amidohydrolase-related GO:0016787 AUP74_RS09115 cc04f91b0c3ec7feb2926c3e36723a69 107 SUPERFAMILY SSF89360 1 96 1.44E-32 T 11-11-2016 IPR000361 FeS cluster biogenesis AUP74_RS09115 cc04f91b0c3ec7feb2926c3e36723a69 107 Gene3D G3DSA:2.60.300.12 2 96 4.8E-35 T 11-11-2016 IPR000361 FeS cluster biogenesis AUP74_RS09115 cc04f91b0c3ec7feb2926c3e36723a69 107 TIGRFAM TIGR02011 IscA: iron-sulfur cluster assembly protein IscA 3 107 1.4E-55 T 11-11-2016 IPR011302 Iron-binding protein IscA, proteobacteria GO:0005506|GO:0016226|GO:0051536 AUP74_RS09115 cc04f91b0c3ec7feb2926c3e36723a69 107 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 88 105 - T 11-11-2016 IPR017870 FeS cluster insertion, C-terminal, conserved site AUP74_RS09115 cc04f91b0c3ec7feb2926c3e36723a69 107 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 3 107 1.6E-36 T 11-11-2016 IPR016092 FeS cluster insertion protein GO:0005198|GO:0016226|GO:0051536 AUP74_RS09115 cc04f91b0c3ec7feb2926c3e36723a69 107 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 103 2.7E-25 T 11-11-2016 IPR000361 FeS cluster biogenesis AUP74_RS06835 b2c902b206042211424ad88a24b4e308 98 Gene3D G3DSA:3.30.70.330 4 94 1.9E-34 T 11-11-2016 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 AUP74_RS06835 b2c902b206042211424ad88a24b4e308 98 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 7 97 21.683 T 11-11-2016 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 AUP74_RS06835 b2c902b206042211424ad88a24b4e308 98 Pfam PF00276 Ribosomal protein L23 8 94 3.0E-31 T 11-11-2016 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 AUP74_RS06835 b2c902b206042211424ad88a24b4e308 98 SUPERFAMILY SSF54189 1 92 6.83E-32 T 11-11-2016 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS04070 7b64e3183bae8943fee25ea43b355ffe 180 SUPERFAMILY SSF69118 4 179 5.04E-44 T 11-11-2016 IPR029032 AhpD-like Reactome: R-HSA-5628897 AUP74_RS04070 7b64e3183bae8943fee25ea43b355ffe 180 Gene3D G3DSA:1.20.1290.10 138 177 6.4E-24 T 11-11-2016 IPR029032 AhpD-like Reactome: R-HSA-5628897 AUP74_RS04070 7b64e3183bae8943fee25ea43b355ffe 180 Gene3D G3DSA:1.20.1290.10 3 88 6.4E-24 T 11-11-2016 IPR029032 AhpD-like Reactome: R-HSA-5628897 AUP74_RS10710 e8818218142f5a70566f677c1ad91ae9 217 Gene3D G3DSA:2.10.109.10 117 215 5.0E-23 T 11-11-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain AUP74_RS10710 e8818218142f5a70566f677c1ad91ae9 217 SUPERFAMILY SSF51306 117 210 8.37E-19 T 11-11-2016 IPR015927 Peptidase S24/S26A/S26B/S26C AUP74_RS10710 e8818218142f5a70566f677c1ad91ae9 217 Pfam PF00717 Peptidase S24-like 135 196 1.1E-8 T 11-11-2016 IPR019759 Peptidase S24/S26A/S26B AUP74_RS07115 a867430101f85a07a368d349306166e7 186 Pfam PF14341 PilX N-terminal 16 63 4.9E-9 T 11-11-2016 IPR025746 Type 4 fimbrial biogenesis protein PilX, N-terminal domain AUP74_RS10195 0a0612cd08f2ea14239ddaff8d96d18b 184 Pfam PF08281 Sigma-70, region 4 115 165 1.2E-6 T 11-11-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS10195 0a0612cd08f2ea14239ddaff8d96d18b 184 Gene3D G3DSA:1.10.1740.10 7 46 9.9E-4 T 11-11-2016 AUP74_RS10195 0a0612cd08f2ea14239ddaff8d96d18b 184 SUPERFAMILY SSF88659 111 169 2.99E-7 T 11-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS10195 0a0612cd08f2ea14239ddaff8d96d18b 184 Gene3D G3DSA:1.10.10.10 112 170 3.3E-7 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS03515 74791dcbe64166a5bc8d165b76526663 145 Pfam PF13511 Domain of unknown function (DUF4124) 10 63 1.7E-12 T 11-11-2016 IPR025392 Domain of unknown function DUF4124 AUP74_RS14380 6c54fdbfa1ec001c12bb8039fc4d1044 172 Gene3D G3DSA:3.10.129.10 14 163 1.4E-48 T 11-11-2016 IPR029069 HotDog domain AUP74_RS14380 6c54fdbfa1ec001c12bb8039fc4d1044 172 SUPERFAMILY SSF54637 13 163 9.13E-51 T 11-11-2016 IPR029069 HotDog domain AUP74_RS14380 6c54fdbfa1ec001c12bb8039fc4d1044 172 Pfam PF01575 MaoC like domain 26 138 1.8E-20 T 11-11-2016 IPR002539 MaoC-like domain AUP74_RS08350 c39db3ba9012fde0ae921c10448df9ca 196 Pfam PF01625 Peptide methionine sulfoxide reductase 27 176 1.4E-59 T 11-11-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AUP74_RS08350 c39db3ba9012fde0ae921c10448df9ca 196 Gene3D G3DSA:3.30.1060.10 22 175 7.6E-69 T 11-11-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AUP74_RS08350 c39db3ba9012fde0ae921c10448df9ca 196 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 25 182 35.851 T 11-11-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AUP74_RS08350 c39db3ba9012fde0ae921c10448df9ca 196 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 27 175 6.7E-57 T 11-11-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AUP74_RS08350 c39db3ba9012fde0ae921c10448df9ca 196 SUPERFAMILY SSF55068 16 188 3.79E-74 T 11-11-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AUP74_RS03365 6ed7045b8c985afb4560ba36f93ec99b 651 Pfam PF11074 Domain of unknown function(DUF2779) 373 521 3.7E-26 T 11-11-2016 IPR021301 Domain of unknown functionDUF2779 AUP74_RS16460 e4c6d51116e1f3a211238c050534e0b0 458 Pfam PF00939 Sodium:sulfate symporter transmembrane region 15 454 5.4E-66 T 11-11-2016 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 AUP74_RS16460 e4c6d51116e1f3a211238c050534e0b0 458 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 35 454 2.2E-79 T 11-11-2016 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 AUP74_RS11895 7bae8afbd267214027a9e4a89981fedc 411 Pfam PF05684 Protein of unknown function (DUF819) 10 406 4.6E-99 T 11-11-2016 IPR008537 Protein of unknown function DUF819 AUP74_RS03810 32200ef12901ff60b020da75e6e77fd4 518 PRINTS PR00113 Alkaline phosphatase signature 112 127 2.9E-47 T 11-11-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 AUP74_RS03810 32200ef12901ff60b020da75e6e77fd4 518 PRINTS PR00113 Alkaline phosphatase signature 159 179 2.9E-47 T 11-11-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 AUP74_RS03810 32200ef12901ff60b020da75e6e77fd4 518 PRINTS PR00113 Alkaline phosphatase signature 221 231 2.9E-47 T 11-11-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 AUP74_RS03810 32200ef12901ff60b020da75e6e77fd4 518 PRINTS PR00113 Alkaline phosphatase signature 306 335 2.9E-47 T 11-11-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 AUP74_RS03810 32200ef12901ff60b020da75e6e77fd4 518 PRINTS PR00113 Alkaline phosphatase signature 56 76 2.9E-47 T 11-11-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 AUP74_RS03810 32200ef12901ff60b020da75e6e77fd4 518 Pfam PF00245 Alkaline phosphatase 56 511 5.1E-121 T 11-11-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 AUP74_RS03810 32200ef12901ff60b020da75e6e77fd4 518 SMART SM00098 57 514 1.3E-150 T 11-11-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 AUP74_RS03810 32200ef12901ff60b020da75e6e77fd4 518 SUPERFAMILY SSF53649 32 514 5.4E-146 T 11-11-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 AUP74_RS03810 32200ef12901ff60b020da75e6e77fd4 518 Gene3D G3DSA:3.40.720.10 30 514 2.9E-161 T 11-11-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 AUP74_RS07135 42d8d5e26f054e48388d165eb85c5119 356 Pfam PF16074 Type IV Pilus-assembly protein W 241 352 1.5E-16 T 11-11-2016 IPR032092 Type IV Pilus-assembly protein W GO:0043683 AUP74_RS07135 42d8d5e26f054e48388d165eb85c5119 356 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 5 29 1.9E-6 T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS07135 42d8d5e26f054e48388d165eb85c5119 356 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 8 28 - T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS07135 42d8d5e26f054e48388d165eb85c5119 356 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 7 26 2.0E-4 T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS15990 82ac8b1db513df7f0504a310a2477a21 204 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 11 200 6.4E-46 T 11-11-2016 IPR010089 Flavoprotein WrbA GO:0010181|GO:0045892 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 AUP74_RS15990 82ac8b1db513df7f0504a310a2477a21 204 Pfam PF03358 NADPH-dependent FMN reductase 19 136 4.2E-7 T 11-11-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 AUP74_RS15990 82ac8b1db513df7f0504a310a2477a21 204 ProSitePatterns PS00201 Flavodoxin signature. 13 29 - T 11-11-2016 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 AUP74_RS15990 82ac8b1db513df7f0504a310a2477a21 204 SUPERFAMILY SSF52218 10 200 1.02E-56 T 11-11-2016 IPR029039 Flavoprotein-like domain AUP74_RS15990 82ac8b1db513df7f0504a310a2477a21 204 Gene3D G3DSA:3.40.50.360 9 203 5.8E-66 T 11-11-2016 IPR029039 Flavoprotein-like domain AUP74_RS08755 c4e6369580fe9442cb8d6f43c0c07f9b 343 Gene3D G3DSA:3.40.50.300 7 52 1.2E-20 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS08755 c4e6369580fe9442cb8d6f43c0c07f9b 343 Gene3D G3DSA:3.40.50.300 117 245 1.2E-20 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS08755 c4e6369580fe9442cb8d6f43c0c07f9b 343 SUPERFAMILY SSF52540 77 293 3.53E-31 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS08755 c4e6369580fe9442cb8d6f43c0c07f9b 343 SUPERFAMILY SSF52540 8 42 3.53E-31 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS08755 c4e6369580fe9442cb8d6f43c0c07f9b 343 Pfam PF13469 Sulfotransferase family 8 236 7.3E-29 T 11-11-2016 AUP74_RS08885 bc710f59d5fc3a57a73445d269405350 188 Pfam PF02563 Polysaccharide biosynthesis/export protein 35 109 1.2E-17 T 11-11-2016 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 AUP74_RS08885 bc710f59d5fc3a57a73445d269405350 188 Pfam PF10531 SLBB domain 115 159 2.3E-7 T 11-11-2016 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS08885 bc710f59d5fc3a57a73445d269405350 188 Gene3D G3DSA:3.30.1950.10 43 113 2.6E-16 T 11-11-2016 AUP74_RS08885 bc710f59d5fc3a57a73445d269405350 188 Gene3D G3DSA:3.10.560.10 115 184 5.5E-11 T 11-11-2016 AUP74_RS09280 da3802c556c86faadacaf309281a6fca 162 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 110 128 - T 11-11-2016 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09280 da3802c556c86faadacaf309281a6fca 162 PIRSF PIRSF000216 2 162 3.0E-40 T 11-11-2016 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09280 da3802c556c86faadacaf309281a6fca 162 Gene3D G3DSA:3.40.30.10 75 151 4.0E-4 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS09280 da3802c556c86faadacaf309281a6fca 162 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 11 151 8.2E-39 T 11-11-2016 AUP74_RS09280 da3802c556c86faadacaf309281a6fca 162 SUPERFAMILY SSF52833 2 153 2.35E-38 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS07520 d94f3a8f8c3cfd2312b3ec561d875ab3 278 SMART SM00384 221 233 4.0 T 11-11-2016 IPR017956 AT hook, DNA-binding motif GO:0003677 AUP74_RS07520 d94f3a8f8c3cfd2312b3ec561d875ab3 278 SMART SM00384 237 249 8.4 T 11-11-2016 IPR017956 AT hook, DNA-binding motif GO:0003677 AUP74_RS07520 d94f3a8f8c3cfd2312b3ec561d875ab3 278 SMART SM00384 253 265 8.4 T 11-11-2016 IPR017956 AT hook, DNA-binding motif GO:0003677 AUP74_RS07520 d94f3a8f8c3cfd2312b3ec561d875ab3 278 PRINTS PR00929 AT-hook-like domain signature 251 261 9.1E-6 T 11-11-2016 IPR017956 AT hook, DNA-binding motif GO:0003677 AUP74_RS07520 d94f3a8f8c3cfd2312b3ec561d875ab3 278 PRINTS PR00929 AT-hook-like domain signature 235 246 9.1E-6 T 11-11-2016 IPR017956 AT hook, DNA-binding motif GO:0003677 AUP74_RS07520 d94f3a8f8c3cfd2312b3ec561d875ab3 278 PRINTS PR00929 AT-hook-like domain signature 221 231 9.1E-6 T 11-11-2016 IPR017956 AT hook, DNA-binding motif GO:0003677 AUP74_RS10915 d0c688b3fd6eec580b096b023c2cdec2 144 SUPERFAMILY SSF82784 10 138 4.71E-27 T 11-11-2016 IPR003718 OsmC/Ohr family AUP74_RS10915 d0c688b3fd6eec580b096b023c2cdec2 144 Gene3D G3DSA:3.30.300.20 5 140 1.8E-29 T 11-11-2016 IPR015946 K homology domain-like, alpha/beta AUP74_RS10915 d0c688b3fd6eec580b096b023c2cdec2 144 Pfam PF02566 OsmC-like protein 40 138 6.3E-18 T 11-11-2016 IPR003718 OsmC/Ohr family AUP74_RS11990 3598025abcfb3f5b985fed4faeafeb4a 752 SUPERFAMILY SSF56935 31 752 1.98E-121 T 11-11-2016 AUP74_RS11990 3598025abcfb3f5b985fed4faeafeb4a 752 Gene3D G3DSA:2.170.130.10 33 172 8.6E-33 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS11990 3598025abcfb3f5b985fed4faeafeb4a 752 Gene3D G3DSA:2.40.170.20 179 752 5.2E-94 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS11990 3598025abcfb3f5b985fed4faeafeb4a 752 Pfam PF07715 TonB-dependent Receptor Plug Domain 55 164 6.1E-17 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS11990 3598025abcfb3f5b985fed4faeafeb4a 752 Pfam PF00593 TonB dependent receptor 481 751 2.6E-28 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS00925 8e0dd621d5fa044e49ff17eee94a909f 229 Pfam PF01618 MotA/TolQ/ExbB proton channel family 85 212 1.0E-41 T 11-11-2016 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 AUP74_RS00925 8e0dd621d5fa044e49ff17eee94a909f 229 TIGRFAM TIGR02796 tolQ: protein TolQ 8 224 2.0E-88 T 11-11-2016 IPR014163 Tol-Pal system, TolQ GO:0015031|GO:0016021 AUP74_RS12895 8807e1d8b35b593594490a786df09861 532 Gene3D G3DSA:3.20.20.60 7 271 6.7E-135 T 11-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AUP74_RS12895 8807e1d8b35b593594490a786df09861 532 Gene3D G3DSA:3.20.20.60 304 393 6.7E-135 T 11-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AUP74_RS12895 8807e1d8b35b593594490a786df09861 532 Gene3D G3DSA:3.20.20.60 430 515 6.7E-135 T 11-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AUP74_RS12895 8807e1d8b35b593594490a786df09861 532 SUPERFAMILY SSF51621 17 393 3.86E-122 T 11-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AUP74_RS12895 8807e1d8b35b593594490a786df09861 532 SUPERFAMILY SSF51621 430 515 3.86E-122 T 11-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 AUP74_RS12895 8807e1d8b35b593594490a786df09861 532 Pfam PF00463 Isocitrate lyase family 330 391 1.9E-9 T 11-11-2016 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 AUP74_RS12895 8807e1d8b35b593594490a786df09861 532 Pfam PF00463 Isocitrate lyase family 99 270 3.2E-20 T 11-11-2016 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 AUP74_RS12895 8807e1d8b35b593594490a786df09861 532 Pfam PF00463 Isocitrate lyase family 433 531 5.2E-13 T 11-11-2016 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 AUP74_RS01730 cd3be0425809ca8143cecfcf77142fd2 124 SUPERFAMILY SSF49503 18 124 2.15E-15 T 11-11-2016 IPR008972 Cupredoxin AUP74_RS01730 cd3be0425809ca8143cecfcf77142fd2 124 Pfam PF13473 Cupredoxin-like domain 13 123 3.3E-26 T 11-11-2016 IPR028096 EfeO-type cupredoxin-like domain AUP74_RS01730 cd3be0425809ca8143cecfcf77142fd2 124 Gene3D G3DSA:2.60.40.420 42 121 4.7E-7 T 11-11-2016 IPR008972 Cupredoxin AUP74_RS16810 cade255e7cc67c216be278e79810b52f 196 SUPERFAMILY SSF53697 1 189 2.6E-39 T 11-11-2016 AUP74_RS16810 cade255e7cc67c216be278e79810b52f 196 Pfam PF13580 SIS domain 21 144 2.1E-28 T 11-11-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 AUP74_RS16810 cade255e7cc67c216be278e79810b52f 196 Gene3D G3DSA:3.40.50.10490 1 191 2.3E-40 T 11-11-2016 AUP74_RS11995 d70a0824c5da2c281dd3714918907493 488 Pfam PF00474 Sodium:solute symporter family 35 423 1.7E-34 T 11-11-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 AUP74_RS15640 a9d44e1b62f0a8dd9d67040708336f53 185 Pfam PF01765 Ribosome recycling factor 22 183 6.9E-63 T 11-11-2016 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 AUP74_RS15640 a9d44e1b62f0a8dd9d67040708336f53 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 4.1E-71 T 11-11-2016 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 AUP74_RS15640 a9d44e1b62f0a8dd9d67040708336f53 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 27.157 T 11-11-2016 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 AUP74_RS15640 a9d44e1b62f0a8dd9d67040708336f53 185 Gene3D G3DSA:1.10.132.20 66 185 3.2E-43 T 11-11-2016 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 AUP74_RS15640 a9d44e1b62f0a8dd9d67040708336f53 185 SUPERFAMILY SSF55194 3 184 1.11E-69 T 11-11-2016 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 AUP74_RS11630 ba1654ff9b31c04cfb480555e4126c65 151 Gene3D G3DSA:1.20.1260.10 19 135 2.7E-7 T 11-11-2016 IPR012347 Ferritin-related AUP74_RS11630 ba1654ff9b31c04cfb480555e4126c65 151 SUPERFAMILY SSF47240 20 135 1.22E-5 T 11-11-2016 IPR009078 Ferritin-like superfamily AUP74_RS10490 ae22b82c3d4984bdf3fc3daa27a31bc8 156 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 151 33.685 T 11-11-2016 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 AUP74_RS10490 ae22b82c3d4984bdf3fc3daa27a31bc8 156 Gene3D G3DSA:3.40.1280.10 1 153 5.9E-67 T 11-11-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AUP74_RS10490 ae22b82c3d4984bdf3fc3daa27a31bc8 156 Pfam PF00588 SpoU rRNA Methylase family 2 142 3.5E-34 T 11-11-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 AUP74_RS10490 ae22b82c3d4984bdf3fc3daa27a31bc8 156 PIRSF PIRSF029256 1 154 3.5E-65 T 11-11-2016 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 AUP74_RS10490 ae22b82c3d4984bdf3fc3daa27a31bc8 156 SUPERFAMILY SSF75217 2 152 5.04E-45 T 11-11-2016 IPR029028 Alpha/beta knot methyltransferases AUP74_RS10490 ae22b82c3d4984bdf3fc3daa27a31bc8 156 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 1 153 2.8E-63 T 11-11-2016 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 AUP74_RS10500 d39a27de56014d6b05e8e08478cccbf1 100 Gene3D G3DSA:3.30.70.930 1 99 2.1E-40 T 11-11-2016 IPR029756 MTH1187/YkoF-like AUP74_RS10500 d39a27de56014d6b05e8e08478cccbf1 100 SUPERFAMILY SSF89957 1 99 1.57E-35 T 11-11-2016 IPR029756 MTH1187/YkoF-like AUP74_RS10500 d39a27de56014d6b05e8e08478cccbf1 100 Pfam PF01910 Thiamine-binding protein 5 95 1.4E-33 T 11-11-2016 IPR002767 Thiamine-binding protein AUP74_RS10500 d39a27de56014d6b05e8e08478cccbf1 100 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 4 98 6.5E-35 T 11-11-2016 IPR002767 Thiamine-binding protein AUP74_RS02100 26f7544298d49351129c77419aa3ac1f 370 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AUP74_RS02100 26f7544298d49351129c77419aa3ac1f 370 SMART SM00382 29 211 2.1E-10 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS02100 26f7544298d49351129c77419aa3ac1f 370 SUPERFAMILY SSF52540 4 243 1.87E-82 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS02100 26f7544298d49351129c77419aa3ac1f 370 SUPERFAMILY SSF50331 237 354 8.26E-24 T 11-11-2016 IPR008995 Molybdate/tungstate binding, C-terminal AUP74_RS02100 26f7544298d49351129c77419aa3ac1f 370 Pfam PF08402 TOBE domain 273 346 4.5E-8 T 11-11-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 AUP74_RS02100 26f7544298d49351129c77419aa3ac1f 370 Pfam PF00005 ABC transporter 22 162 9.1E-30 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AUP74_RS02100 26f7544298d49351129c77419aa3ac1f 370 Gene3D G3DSA:3.40.50.300 3 234 1.9E-72 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS02100 26f7544298d49351129c77419aa3ac1f 370 Gene3D G3DSA:2.40.50.140 276 339 8.8E-15 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS14765 2f112f1536a47007fe82ab09ef6ea6e5 308 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 212 9.2E-19 T 11-11-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 AUP74_RS14765 2f112f1536a47007fe82ab09ef6ea6e5 308 SUPERFAMILY SSF51735 4 304 3.77E-38 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS14765 2f112f1536a47007fe82ab09ef6ea6e5 308 Gene3D G3DSA:3.40.50.720 3 245 3.2E-30 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS03970 3264b846b65cd5722de7602e3e2662a9 107 SUPERFAMILY SSF103481 7 106 1.02E-19 T 11-11-2016 AUP74_RS03970 3264b846b65cd5722de7602e3e2662a9 107 Pfam PF00893 Small Multidrug Resistance protein 4 95 8.1E-30 T 11-11-2016 IPR000390 Small multidrug resistance protein family GO:0016021 AUP74_RS16015 b3496faeef4db4c876ec3fa279782ff5 407 SUPERFAMILY SSF53448 38 406 1.8E-90 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases AUP74_RS14100 c30144ad81ac140bc52ae81636ddcd5b 92 SUPERFAMILY SSF54427 1 87 2.54E-25 T 11-11-2016 IPR032710 NTF2-like domain AUP74_RS14100 c30144ad81ac140bc52ae81636ddcd5b 92 Gene3D G3DSA:3.10.450.50 1 87 4.8E-24 T 11-11-2016 IPR032710 NTF2-like domain AUP74_RS11360 dff1baf1a86623632247db51008411e4 188 SUPERFAMILY SSF52833 5 187 4.69E-61 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS11360 dff1baf1a86623632247db51008411e4 188 TIGRFAM TIGR03137 AhpC: peroxiredoxin 5 188 5.5E-104 T 11-11-2016 IPR017559 Alkyl hydroperoxide reductase subunit C GO:0006979|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AUP74_RS11360 dff1baf1a86623632247db51008411e4 188 Gene3D G3DSA:3.40.30.10 5 184 2.6E-67 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS11360 dff1baf1a86623632247db51008411e4 188 PIRSF PIRSF000239 1 188 2.1E-57 T 11-11-2016 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AUP74_RS11360 dff1baf1a86623632247db51008411e4 188 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 157 182 9.9E-7 T 11-11-2016 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AUP74_RS11360 dff1baf1a86623632247db51008411e4 188 Pfam PF00578 AhpC/TSA family 5 133 5.7E-37 T 11-11-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AUP74_RS10885 e678a43ade6a512a9e374fce05bd3cd7 255 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 157 183 3.0E-50 T 11-11-2016 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 AUP74_RS10885 e678a43ade6a512a9e374fce05bd3cd7 255 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 122 142 3.0E-50 T 11-11-2016 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 AUP74_RS10885 e678a43ade6a512a9e374fce05bd3cd7 255 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 63 83 3.0E-50 T 11-11-2016 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 AUP74_RS10885 e678a43ade6a512a9e374fce05bd3cd7 255 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 46 63 3.0E-50 T 11-11-2016 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 AUP74_RS10885 e678a43ade6a512a9e374fce05bd3cd7 255 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 101 121 3.0E-50 T 11-11-2016 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 AUP74_RS10885 e678a43ade6a512a9e374fce05bd3cd7 255 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 205 229 3.0E-50 T 11-11-2016 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 AUP74_RS10885 e678a43ade6a512a9e374fce05bd3cd7 255 Pfam PF01578 Cytochrome C assembly protein 28 185 2.6E-25 T 11-11-2016 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 AUP74_RS10885 e678a43ade6a512a9e374fce05bd3cd7 255 TIGRFAM TIGR01191 ccmC: heme exporter protein CcmC 46 229 2.1E-73 T 11-11-2016 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 AUP74_RS00310 64b7c5ce854d2b048dfb450786f69ba3 451 Pfam PF00691 OmpA family 344 435 7.1E-5 T 11-11-2016 IPR006665 OmpA-like domain AUP74_RS00310 64b7c5ce854d2b048dfb450786f69ba3 451 Pfam PF12849 PBP superfamily domain 87 294 1.6E-24 T 11-11-2016 IPR024370 PBP domain AUP74_RS00310 64b7c5ce854d2b048dfb450786f69ba3 451 SUPERFAMILY SSF53850 84 354 2.58E-54 T 11-11-2016 AUP74_RS00310 64b7c5ce854d2b048dfb450786f69ba3 451 SUPERFAMILY SSF53850 37 56 2.58E-54 T 11-11-2016 AUP74_RS00310 64b7c5ce854d2b048dfb450786f69ba3 451 Gene3D G3DSA:3.40.190.10 141 272 3.2E-28 T 11-11-2016 AUP74_RS00310 64b7c5ce854d2b048dfb450786f69ba3 451 Gene3D G3DSA:3.30.1330.60 335 443 5.1E-7 T 11-11-2016 IPR006665 OmpA-like domain AUP74_RS00310 64b7c5ce854d2b048dfb450786f69ba3 451 SUPERFAMILY SSF103088 316 443 2.35E-7 T 11-11-2016 IPR006665 OmpA-like domain AUP74_RS08575 1f4f9d1062e9a8b9471b510b63b7dd08 235 ProSitePatterns PS00622 LuxR-type HTH domain signature. 174 201 - T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS08575 1f4f9d1062e9a8b9471b510b63b7dd08 235 Gene3D G3DSA:3.40.50.2300 12 135 1.4E-21 T 11-11-2016 AUP74_RS08575 1f4f9d1062e9a8b9471b510b63b7dd08 235 Pfam PF00196 Bacterial regulatory proteins, luxR family 159 212 2.0E-18 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS08575 1f4f9d1062e9a8b9471b510b63b7dd08 235 SUPERFAMILY SSF52172 12 140 3.98E-21 T 11-11-2016 IPR011006 CheY-like superfamily AUP74_RS08575 1f4f9d1062e9a8b9471b510b63b7dd08 235 SMART SM00448 11 125 1.5E-7 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS08575 1f4f9d1062e9a8b9471b510b63b7dd08 235 Gene3D G3DSA:1.10.10.10 149 214 9.3E-23 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS08575 1f4f9d1062e9a8b9471b510b63b7dd08 235 SUPERFAMILY SSF46894 150 216 5.44E-19 T 11-11-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AUP74_RS08575 1f4f9d1062e9a8b9471b510b63b7dd08 235 Pfam PF00072 Response regulator receiver domain 14 125 5.5E-16 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AUP74_RS08575 1f4f9d1062e9a8b9471b510b63b7dd08 235 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 174 7.8E-10 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS08575 1f4f9d1062e9a8b9471b510b63b7dd08 235 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 202 7.8E-10 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS08575 1f4f9d1062e9a8b9471b510b63b7dd08 235 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 190 7.8E-10 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS08575 1f4f9d1062e9a8b9471b510b63b7dd08 235 SMART SM00421 157 214 1.2E-21 T 11-11-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AUP74_RS14935 42d64e9c1ff967837ef6711e3634b17a 273 Pfam PF03922 OmpW family 34 271 8.5E-15 T 11-11-2016 IPR005618 Outer membrane protein, OmpW GO:0019867 AUP74_RS14935 42d64e9c1ff967837ef6711e3634b17a 273 SUPERFAMILY SSF56925 81 271 2.22E-15 T 11-11-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AUP74_RS14935 42d64e9c1ff967837ef6711e3634b17a 273 SUPERFAMILY SSF56925 33 52 2.22E-15 T 11-11-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AUP74_RS14935 42d64e9c1ff967837ef6711e3634b17a 273 Gene3D G3DSA:2.40.160.20 33 271 5.8E-27 T 11-11-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AUP74_RS11025 6f54e86409d427a03d086eb6df3ba1e4 373 Pfam PF00246 Zinc carboxypeptidase 123 229 2.1E-20 T 11-11-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 AUP74_RS11025 6f54e86409d427a03d086eb6df3ba1e4 373 SMART SM00631 107 332 3.8E-4 T 11-11-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 AUP74_RS11025 6f54e86409d427a03d086eb6df3ba1e4 373 SUPERFAMILY SSF53187 105 366 3.49E-60 T 11-11-2016 AUP74_RS11025 6f54e86409d427a03d086eb6df3ba1e4 373 Gene3D G3DSA:3.40.630.10 96 340 1.1E-39 T 11-11-2016 AUP74_RS15600 a0c094a34555e2fa212cef283b50f8be 145 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 2 141 7.8E-60 T 11-11-2016 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 AUP74_RS15600 a0c094a34555e2fa212cef283b50f8be 145 Gene3D G3DSA:3.10.129.10 1 143 8.0E-55 T 11-11-2016 IPR029069 HotDog domain AUP74_RS15600 a0c094a34555e2fa212cef283b50f8be 145 SUPERFAMILY SSF54637 1 142 1.2E-47 T 11-11-2016 IPR029069 HotDog domain AUP74_RS15600 a0c094a34555e2fa212cef283b50f8be 145 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 2 144 34.268 T 11-11-2016 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 AUP74_RS15600 a0c094a34555e2fa212cef283b50f8be 145 Pfam PF07977 FabA-like domain 11 136 2.8E-34 T 11-11-2016 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 AUP74_RS00225 9121a23e60bdcccaac2abe05679f0a89 343 Pfam PF01925 Sulfite exporter TauE/SafE 42 281 7.1E-24 T 11-11-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 AUP74_RS02650 c6c7a5e2bd299955cb2fbf31d698f39c 150 Pfam PF04273 Putative phosphatase (DUF442) 6 102 3.8E-8 T 11-11-2016 IPR005939 Beta-lactamase hydrolase-like GO:0016787 AUP74_RS02650 c6c7a5e2bd299955cb2fbf31d698f39c 150 Gene3D G3DSA:3.90.190.10 2 126 1.4E-22 T 11-11-2016 IPR029021 Protein-tyrosine phosphatase-like AUP74_RS02650 c6c7a5e2bd299955cb2fbf31d698f39c 150 SUPERFAMILY SSF52799 6 126 5.16E-11 T 11-11-2016 IPR029021 Protein-tyrosine phosphatase-like AUP74_RS13850 4663137f00ab91c422d3da3fc4441c13 184 SUPERFAMILY SSF88946 2 103 3.14E-26 T 11-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS13850 4663137f00ab91c422d3da3fc4441c13 184 Gene3D G3DSA:1.10.1740.10 3 111 2.3E-30 T 11-11-2016 AUP74_RS13850 4663137f00ab91c422d3da3fc4441c13 184 SUPERFAMILY SSF88659 116 174 1.57E-14 T 11-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS13850 4663137f00ab91c422d3da3fc4441c13 184 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 173 1.0E-26 T 11-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS13850 4663137f00ab91c422d3da3fc4441c13 184 Pfam PF04542 Sigma-70 region 2 24 91 3.9E-15 T 11-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS13850 4663137f00ab91c422d3da3fc4441c13 184 Gene3D G3DSA:1.10.10.10 117 175 1.7E-19 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS13850 4663137f00ab91c422d3da3fc4441c13 184 Pfam PF08281 Sigma-70, region 4 119 170 2.0E-14 T 11-11-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AUP74_RS03530 9476254cb017590dae7a329b31ebc7ad 227 Gene3D G3DSA:3.30.1380.10 122 227 9.8E-13 T 11-11-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 AUP74_RS03530 9476254cb017590dae7a329b31ebc7ad 227 Pfam PF08291 Peptidase M15 125 195 2.9E-8 T 11-11-2016 IPR013230 Peptidase M15A, C-terminal MetaCyc: PWY-6470 AUP74_RS03530 9476254cb017590dae7a329b31ebc7ad 227 SUPERFAMILY SSF55166 109 227 8.63E-10 T 11-11-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 AUP74_RS08920 42334015e2fe62e013fff2f230001ad2 188 Gene3D G3DSA:2.60.120.10 1 181 1.6E-75 T 11-11-2016 IPR014710 RmlC-like jelly roll fold AUP74_RS08920 42334015e2fe62e013fff2f230001ad2 188 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 3 177 5.9E-71 T 11-11-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 AUP74_RS08920 42334015e2fe62e013fff2f230001ad2 188 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 169 1.0E-60 T 11-11-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 AUP74_RS08920 42334015e2fe62e013fff2f230001ad2 188 SUPERFAMILY SSF51182 1 179 2.76E-70 T 11-11-2016 IPR011051 RmlC-like cupin domain AUP74_RS08920 42334015e2fe62e013fff2f230001ad2 188 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 176 6.8E-67 T 11-11-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 AUP74_RS04965 f107d0aaa5788d65f7bb68d09c834e4b 135 Pfam PF13211 Protein of unknown function (DUF4019) 32 132 1.2E-33 T 11-11-2016 IPR025091 Protein of unknown function DUF4019 AUP74_RS07745 d5b8f76ce9efb0f24dc99dfa2846d612 579 Gene3D G3DSA:2.30.40.10 482 561 5.5E-14 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS07745 d5b8f76ce9efb0f24dc99dfa2846d612 579 Pfam PF07969 Amidohydrolase family 48 190 3.0E-7 T 11-11-2016 IPR013108 Amidohydrolase 3 AUP74_RS07745 d5b8f76ce9efb0f24dc99dfa2846d612 579 Pfam PF07969 Amidohydrolase family 478 556 5.4E-8 T 11-11-2016 IPR013108 Amidohydrolase 3 AUP74_RS07745 d5b8f76ce9efb0f24dc99dfa2846d612 579 SUPERFAMILY SSF51556 60 319 2.83E-40 T 11-11-2016 IPR032466 Metal-dependent hydrolase AUP74_RS07745 d5b8f76ce9efb0f24dc99dfa2846d612 579 SUPERFAMILY SSF51556 367 497 2.83E-40 T 11-11-2016 IPR032466 Metal-dependent hydrolase AUP74_RS07745 d5b8f76ce9efb0f24dc99dfa2846d612 579 SUPERFAMILY SSF51338 500 566 3.35E-19 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS07745 d5b8f76ce9efb0f24dc99dfa2846d612 579 SUPERFAMILY SSF51338 4 59 3.35E-19 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS07745 d5b8f76ce9efb0f24dc99dfa2846d612 579 Gene3D G3DSA:2.30.40.10 4 73 3.2E-17 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 AUP74_RS07745 d5b8f76ce9efb0f24dc99dfa2846d612 579 Gene3D G3DSA:3.20.20.140 422 481 1.5E-76 T 11-11-2016 AUP74_RS07745 d5b8f76ce9efb0f24dc99dfa2846d612 579 Gene3D G3DSA:3.20.20.140 74 311 1.5E-76 T 11-11-2016 AUP74_RS08410 7c9f0bd7cbbbd7561d76bec75b262efa 191 SUPERFAMILY SSF88697 3 186 3.73E-44 T 11-11-2016 IPR015947 PUA-like domain AUP74_RS08410 7c9f0bd7cbbbd7561d76bec75b262efa 191 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 4 182 5.1E-24 T 11-11-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 AUP74_RS08410 7c9f0bd7cbbbd7561d76bec75b262efa 191 SMART SM00464 3 187 8.7E-23 T 11-11-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 AUP74_RS04370 b9bd410f43b5ef6b9929d9a405f23c52 265 Pfam PF01226 Formate/nitrite transporter 17 259 1.6E-43 T 11-11-2016 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 AUP74_RS04370 b9bd410f43b5ef6b9929d9a405f23c52 265 Gene3D G3DSA:1.20.1080.10 32 260 4.9E-40 T 11-11-2016 IPR023271 Aquaporin-like Reactome: R-HSA-432047 AUP74_RS08595 0eb8485bebeacada5f0287155a816649 568 Pfam PF00474 Sodium:solute symporter family 33 304 2.5E-32 T 11-11-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 AUP74_RS08595 0eb8485bebeacada5f0287155a816649 568 Pfam PF00474 Sodium:solute symporter family 375 490 1.8E-17 T 11-11-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 AUP74_RS08595 0eb8485bebeacada5f0287155a816649 568 TIGRFAM TIGR03648 Na_symport_lg: probable sodium:solute symporter, VC_2705 subfamily 8 559 2.6E-265 T 11-11-2016 IPR019899 Sodium/solute symporter, VC2705 subfamily AUP74_RS04615 51e9234f84c8e03677f9f8e2ac3cb3ea 303 SUPERFAMILY SSF55909 20 301 3.39E-52 T 11-11-2016 AUP74_RS04615 51e9234f84c8e03677f9f8e2ac3cb3ea 303 Gene3D G3DSA:3.75.10.10 30 298 7.4E-60 T 11-11-2016 AUP74_RS04615 51e9234f84c8e03677f9f8e2ac3cb3ea 303 Pfam PF02274 Amidinotransferase 59 300 9.9E-45 T 11-11-2016 AUP74_RS04550 b28d250325ab4f26a352d821854df92f 483 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 84 466 3.3E-105 T 11-11-2016 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 AUP74_RS04550 b28d250325ab4f26a352d821854df92f 483 PIRSF PIRSF006247 1 483 4.9E-165 T 11-11-2016 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 AUP74_RS04550 b28d250325ab4f26a352d821854df92f 483 Pfam PF02386 Cation transport protein 37 475 1.7E-82 T 11-11-2016 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 AUP74_RS13285 5969dd2141cc3aaedce3c766058d4ce8 377 SUPERFAMILY SSF82689 269 364 1.06E-22 T 11-11-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 AUP74_RS13285 5969dd2141cc3aaedce3c766058d4ce8 377 Gene3D G3DSA:3.30.70.100 269 351 1.7E-19 T 11-11-2016 AUP74_RS13285 5969dd2141cc3aaedce3c766058d4ce8 377 Gene3D G3DSA:2.30.30.60 211 260 1.9E-16 T 11-11-2016 AUP74_RS13285 5969dd2141cc3aaedce3c766058d4ce8 377 Pfam PF00924 Mechanosensitive ion channel 156 354 9.2E-49 T 11-11-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 AUP74_RS13285 5969dd2141cc3aaedce3c766058d4ce8 377 SUPERFAMILY SSF50182 195 261 9.15E-16 T 11-11-2016 IPR010920 LSM domain AUP74_RS13285 5969dd2141cc3aaedce3c766058d4ce8 377 SUPERFAMILY SSF82861 115 194 2.22E-6 T 11-11-2016 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 AUP74_RS16345 e35b40dc252a093f090fbe4b5f247837 220 Pfam PF00881 Nitroreductase family 7 195 1.1E-29 T 11-11-2016 IPR029479 Nitroreductase Reactome: R-HSA-209968 AUP74_RS16345 e35b40dc252a093f090fbe4b5f247837 220 SUPERFAMILY SSF55469 1 211 1.24E-43 T 11-11-2016 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AUP74_RS16345 e35b40dc252a093f090fbe4b5f247837 220 Gene3D G3DSA:3.40.109.10 1 89 9.9E-45 T 11-11-2016 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AUP74_RS16345 e35b40dc252a093f090fbe4b5f247837 220 Gene3D G3DSA:3.40.109.10 121 212 9.9E-45 T 11-11-2016 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AUP74_RS00330 f8c963a9fdf515edbb088b73914a588f 263 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 7 225 3.2E-12 T 11-11-2016 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 AUP74_RS00330 f8c963a9fdf515edbb088b73914a588f 263 SUPERFAMILY SSF56300 183 241 2.73E-26 T 11-11-2016 IPR029052 Metallo-dependent phosphatase-like AUP74_RS00330 f8c963a9fdf515edbb088b73914a588f 263 SUPERFAMILY SSF56300 6 127 2.73E-26 T 11-11-2016 IPR029052 Metallo-dependent phosphatase-like AUP74_RS00330 f8c963a9fdf515edbb088b73914a588f 263 Gene3D G3DSA:3.60.21.10 190 245 1.4E-27 T 11-11-2016 IPR029052 Metallo-dependent phosphatase-like AUP74_RS00330 f8c963a9fdf515edbb088b73914a588f 263 Gene3D G3DSA:3.60.21.10 6 149 1.4E-27 T 11-11-2016 IPR029052 Metallo-dependent phosphatase-like AUP74_RS15455 bf4dfef3df767b9b1d319053ef8ef703 331 Pfam PF13449 Esterase-like activity of phytase 48 224 3.1E-7 T 11-11-2016 IPR027372 Phytase-like domain AUP74_RS13380 fde5c48fe7fb1227531c532882c98a20 299 SUPERFAMILY SSF52821 7 146 1.7E-41 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS13380 fde5c48fe7fb1227531c532882c98a20 299 Pfam PF00581 Rhodanese-like domain 174 277 7.4E-10 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS13380 fde5c48fe7fb1227531c532882c98a20 299 Pfam PF00581 Rhodanese-like domain 23 136 2.5E-20 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS13380 fde5c48fe7fb1227531c532882c98a20 299 Gene3D G3DSA:3.40.250.10 163 277 6.5E-31 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS13380 fde5c48fe7fb1227531c532882c98a20 299 Gene3D G3DSA:3.40.250.10 6 147 3.7E-50 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS13380 fde5c48fe7fb1227531c532882c98a20 299 SMART SM00450 8 139 8.1E-22 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS13380 fde5c48fe7fb1227531c532882c98a20 299 SMART SM00450 164 281 2.0E-9 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS13380 fde5c48fe7fb1227531c532882c98a20 299 SUPERFAMILY SSF52821 167 283 1.57E-29 T 11-11-2016 IPR001763 Rhodanese-like domain AUP74_RS07010 60856e3e97f98bda327c7637f02e8f34 174 SUPERFAMILY SSF54637 6 171 4.85E-57 T 11-11-2016 IPR029069 HotDog domain AUP74_RS07010 60856e3e97f98bda327c7637f02e8f34 174 Gene3D G3DSA:3.10.129.10 6 170 1.9E-58 T 11-11-2016 IPR029069 HotDog domain AUP74_RS07010 60856e3e97f98bda327c7637f02e8f34 174 Hamap MF_00405 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase [fabA]. 4 174 51.742 T 11-11-2016 IPR010083 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA GO:0005737|GO:0006633|GO:0008693 KEGG: 00061+4.2.1.59+5.3.3.14|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 AUP74_RS07010 60856e3e97f98bda327c7637f02e8f34 174 Pfam PF07977 FabA-like domain 31 161 3.2E-52 T 11-11-2016 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 AUP74_RS07010 60856e3e97f98bda327c7637f02e8f34 174 TIGRFAM TIGR01749 fabA: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA 6 174 1.9E-93 T 11-11-2016 IPR010083 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA GO:0005737|GO:0006633|GO:0008693 KEGG: 00061+4.2.1.59+5.3.3.14|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 AUP74_RS09575 60ba5f90fc676ff370fa53b6a9595c6d 168 Pfam PF04186 FxsA cytoplasmic membrane protein 6 111 1.6E-34 T 11-11-2016 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 AUP74_RS02205 1a5e7e842dc4da121d8c3ccc3fe59f82 371 Pfam PF00534 Glycosyl transferases group 1 191 337 1.2E-22 T 11-11-2016 IPR001296 Glycosyl transferase, family 1 AUP74_RS02205 1a5e7e842dc4da121d8c3ccc3fe59f82 371 SUPERFAMILY SSF53756 6 365 8.48E-64 T 11-11-2016 AUP74_RS02205 1a5e7e842dc4da121d8c3ccc3fe59f82 371 Gene3D G3DSA:3.40.50.2000 185 325 1.5E-17 T 11-11-2016 AUP74_RS02205 1a5e7e842dc4da121d8c3ccc3fe59f82 371 Pfam PF13439 Glycosyltransferase Family 4 13 166 8.4E-27 T 11-11-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AUP74_RS06570 59f48e0f897326957932443dadf7c9df 305 Pfam PF09935 Protein of unknown function (DUF2167) 59 296 4.2E-91 T 11-11-2016 IPR018682 Protein of unknown function DUF2167, membrane AUP74_RS00585 57535f0652b86095057f6cb17ba2c4fa 393 Pfam PF05762 VWA domain containing CoxE-like protein 185 271 2.4E-6 T 11-11-2016 IPR008912 Uncharacterised protein family CoxE-like AUP74_RS16285 7b57c8b9cdebc82a1a6a66940bc703fb 626 Pfam PF00474 Sodium:solute symporter family 36 467 1.7E-27 T 11-11-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 AUP74_RS07675 bde140f760282ce1a8a5ef83e93611a8 432 TIGRFAM TIGR03805 beta_helix_1: parallel beta-helix repeat-containing protein 43 355 1.6E-132 T 11-11-2016 IPR022442 Parallel beta-helix repeat-containing domain AUP74_RS07675 bde140f760282ce1a8a5ef83e93611a8 432 SMART SM00710 126 155 300.0 T 11-11-2016 IPR006626 Parallel beta-helix repeat AUP74_RS07675 bde140f760282ce1a8a5ef83e93611a8 432 SMART SM00710 230 268 2800.0 T 11-11-2016 IPR006626 Parallel beta-helix repeat AUP74_RS07675 bde140f760282ce1a8a5ef83e93611a8 432 SMART SM00710 103 125 8800.0 T 11-11-2016 IPR006626 Parallel beta-helix repeat AUP74_RS07675 bde140f760282ce1a8a5ef83e93611a8 432 SMART SM00710 269 291 1100.0 T 11-11-2016 IPR006626 Parallel beta-helix repeat AUP74_RS07675 bde140f760282ce1a8a5ef83e93611a8 432 SMART SM00710 179 200 7.2 T 11-11-2016 IPR006626 Parallel beta-helix repeat AUP74_RS07675 bde140f760282ce1a8a5ef83e93611a8 432 SMART SM00710 201 222 280.0 T 11-11-2016 IPR006626 Parallel beta-helix repeat AUP74_RS07675 bde140f760282ce1a8a5ef83e93611a8 432 SMART SM00710 156 178 160.0 T 11-11-2016 IPR006626 Parallel beta-helix repeat AUP74_RS07675 bde140f760282ce1a8a5ef83e93611a8 432 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 173 215 9.5E-6 T 11-11-2016 IPR022441 Parallel beta-helix repeat-2 AUP74_RS07675 bde140f760282ce1a8a5ef83e93611a8 432 Gene3D G3DSA:2.160.20.10 260 323 4.3E-13 T 11-11-2016 IPR012334 Pectin lyase fold AUP74_RS07675 bde140f760282ce1a8a5ef83e93611a8 432 Gene3D G3DSA:2.160.20.10 19 223 4.3E-13 T 11-11-2016 IPR012334 Pectin lyase fold AUP74_RS07675 bde140f760282ce1a8a5ef83e93611a8 432 SUPERFAMILY SSF51126 55 330 5.71E-39 T 11-11-2016 IPR011050 Pectin lyase fold/virulence factor AUP74_RS07675 bde140f760282ce1a8a5ef83e93611a8 432 Pfam PF13229 Right handed beta helix region 64 221 2.7E-13 T 11-11-2016 AUP74_RS02170 51b4e5a476305bedd072f9a9bc72e255 187 Pfam PF13590 Domain of unknown function (DUF4136) 34 185 2.7E-10 T 11-11-2016 IPR025411 Domain of unknown function DUF4136 AUP74_RS16935 06daa95d6f549672c3793825c4b90597 173 SUPERFAMILY SSF56784 4 164 3.02E-38 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS16935 06daa95d6f549672c3793825c4b90597 173 Pfam PF08282 haloacid dehalogenase-like hydrolase 82 142 4.4E-5 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS16935 06daa95d6f549672c3793825c4b90597 173 Gene3D G3DSA:3.40.50.1000 3 166 2.0E-41 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS16935 06daa95d6f549672c3793825c4b90597 173 TIGRFAM TIGR01670 KdsC-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family 9 159 6.7E-48 T 11-11-2016 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 AUP74_RS16935 06daa95d6f549672c3793825c4b90597 173 PIRSF PIRSF006118 1 170 1.0E-65 T 11-11-2016 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 AUP74_RS13745 4643d04206fedada881cefd218fae661 145 Pfam PF12680 SnoaL-like domain 10 106 4.4E-11 T 11-11-2016 IPR009959 Polyketide cyclase SnoaL-like domain AUP74_RS13745 4643d04206fedada881cefd218fae661 145 SUPERFAMILY SSF54427 18 125 2.77E-18 T 11-11-2016 IPR032710 NTF2-like domain AUP74_RS13745 4643d04206fedada881cefd218fae661 145 Gene3D G3DSA:3.10.450.50 9 124 8.2E-11 T 11-11-2016 IPR032710 NTF2-like domain AUP74_RS16640 8a50f8beb6e9dbb220231d599952313f 503 Pfam PF00817 impB/mucB/samB family 24 158 1.2E-6 T 11-11-2016 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 AUP74_RS16640 8a50f8beb6e9dbb220231d599952313f 503 SUPERFAMILY SSF56672 1 243 2.67E-25 T 11-11-2016 AUP74_RS16640 8a50f8beb6e9dbb220231d599952313f 503 Gene3D G3DSA:1.10.150.20 195 242 7.4E-4 T 11-11-2016 AUP74_RS16640 8a50f8beb6e9dbb220231d599952313f 503 Gene3D G3DSA:3.30.1490.100 258 353 2.6E-4 T 11-11-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 AUP74_RS07230 10cd220b12bd231aed0c09bec2182d25 274 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 69 91 - T 11-11-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AUP74_RS07230 10cd220b12bd231aed0c09bec2182d25 274 Pfam PF01066 CDP-alcohol phosphatidyltransferase 28 91 2.5E-12 T 11-11-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AUP74_RS07230 10cd220b12bd231aed0c09bec2182d25 274 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 35 194 3.1E-35 T 11-11-2016 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 AUP74_RS00750 d5a2b482e8e1701c91f3162fc6bdcd90 77 Pfam PF10982 Protein of unknown function (DUF2789) 4 75 6.8E-30 T 11-11-2016 IPR021250 Protein of unknown function DUF2789 AUP74_RS10845 0a5c7515029c4666283d817702640071 763 Gene3D G3DSA:3.10.180.10 134 274 9.0E-15 T 11-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AUP74_RS10845 0a5c7515029c4666283d817702640071 763 Gene3D G3DSA:3.10.180.10 290 404 5.7E-19 T 11-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AUP74_RS10845 0a5c7515029c4666283d817702640071 763 Gene3D G3DSA:4.10.1080.10 86 123 9.4E-4 T 11-11-2016 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 AUP74_RS10845 0a5c7515029c4666283d817702640071 763 SUPERFAMILY SSF54593 285 406 1.69E-17 T 11-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AUP74_RS10845 0a5c7515029c4666283d817702640071 763 SUPERFAMILY SSF54593 135 272 4.34E-12 T 11-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AUP74_RS10845 0a5c7515029c4666283d817702640071 763 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 288 401 1.5E-7 T 11-11-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AUP74_RS01640 dcdf178786462291a9685bb5d82e8bb9 328 Pfam PF14027 Protein of unknown function (DUF4243) 26 305 4.1E-41 T 11-11-2016 IPR025337 Domain of unknown function DUF4243 AUP74_RS04645 aac7ac8c9a598459634f76597924aa4d 471 SUPERFAMILY SSF51905 191 325 5.55E-41 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS04645 aac7ac8c9a598459634f76597924aa4d 471 SUPERFAMILY SSF51905 20 136 5.55E-41 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS04645 aac7ac8c9a598459634f76597924aa4d 471 Gene3D G3DSA:3.50.50.60 368 414 3.0E-34 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS04645 aac7ac8c9a598459634f76597924aa4d 471 Gene3D G3DSA:3.50.50.60 187 266 3.0E-34 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS04645 aac7ac8c9a598459634f76597924aa4d 471 Gene3D G3DSA:3.50.50.60 30 133 3.0E-34 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS04645 aac7ac8c9a598459634f76597924aa4d 471 Pfam PF01266 FAD dependent oxidoreductase 43 399 3.2E-45 T 11-11-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AUP74_RS08035 b670007c67e5e42d6bc25ed4a0a139f0 321 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AUP74_RS08035 b670007c67e5e42d6bc25ed4a0a139f0 321 Gene3D G3DSA:3.40.50.300 2 229 3.5E-65 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS08035 b670007c67e5e42d6bc25ed4a0a139f0 321 SUPERFAMILY SSF52540 2 228 7.5E-62 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS08035 b670007c67e5e42d6bc25ed4a0a139f0 321 SMART SM00382 30 214 2.9E-16 T 11-11-2016 IPR003593 AAA+ ATPase domain AUP74_RS08035 b670007c67e5e42d6bc25ed4a0a139f0 321 Pfam PF00005 ABC transporter 21 163 4.1E-31 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AUP74_RS11290 2fa56138716adf0cb948abb8739aabe3 228 Pfam PF16266 Domain of unknown function (DUF4919) 59 205 1.8E-10 T 11-11-2016 IPR032578 Protein of unknown function DUF4919 AUP74_RS05115 2faf0ec8b93cda3269f33eefa1c05975 243 SUPERFAMILY SSF51366 15 225 1.73E-50 T 11-11-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 AUP74_RS05115 2faf0ec8b93cda3269f33eefa1c05975 243 Gene3D G3DSA:3.20.20.70 12 228 6.9E-77 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS05115 2faf0ec8b93cda3269f33eefa1c05975 243 Hamap MF_01235 Putative N-acetylmannosamine-6-phosphate 2-epimerase [nanE]. 13 228 34.283 T 11-11-2016 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9 AUP74_RS05115 2faf0ec8b93cda3269f33eefa1c05975 243 Pfam PF04131 Putative N-acetylmannosamine-6-phosphate epimerase 38 227 2.1E-67 T 11-11-2016 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9 AUP74_RS15150 d335cebe47618564105eb4bdbd51d94f 188 Pfam PF13590 Domain of unknown function (DUF4136) 41 185 1.2E-21 T 11-11-2016 IPR025411 Domain of unknown function DUF4136 AUP74_RS12360 32ab3728cfcb05f8647fcb3aeb590852 391 Pfam PF05134 Type II secretion system (T2SS), protein L 27 232 1.0E-17 T 11-11-2016 IPR024230 GspL, cytoplasmic actin-ATPase-like domain AUP74_RS12360 32ab3728cfcb05f8647fcb3aeb590852 391 Pfam PF12693 GspL periplasmic domain 242 389 2.5E-17 T 11-11-2016 IPR025691 GspL periplasmic domain AUP74_RS12360 32ab3728cfcb05f8647fcb3aeb590852 391 SUPERFAMILY SSF53067 24 120 6.99E-18 T 11-11-2016 AUP74_RS12360 32ab3728cfcb05f8647fcb3aeb590852 391 PIRSF PIRSF015761 34 391 1.3E-31 T 11-11-2016 IPR007812 Type II secretion system protein L GO:0008565|GO:0009276|GO:0015031|GO:0016021 AUP74_RS03435 dc518eb642647d3b4d2e46d9c9c1991c 144 SUPERFAMILY SSF54593 1 135 2.34E-19 T 11-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AUP74_RS03435 dc518eb642647d3b4d2e46d9c9c1991c 144 Gene3D G3DSA:3.10.180.10 6 135 8.1E-21 T 11-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AUP74_RS16190 786f215eea017d869ef7b9af28d8dc04 200 Gene3D G3DSA:3.30.1020.10 162 195 6.1E-14 T 11-11-2016 AUP74_RS16190 786f215eea017d869ef7b9af28d8dc04 200 SUPERFAMILY SSF52833 3 197 1.22E-66 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS16190 786f215eea017d869ef7b9af28d8dc04 200 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 160 194 6.0E-11 T 11-11-2016 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AUP74_RS16190 786f215eea017d869ef7b9af28d8dc04 200 PIRSF PIRSF000239 1 199 2.4E-58 T 11-11-2016 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AUP74_RS16190 786f215eea017d869ef7b9af28d8dc04 200 Pfam PF00578 AhpC/TSA family 5 139 3.6E-33 T 11-11-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AUP74_RS16190 786f215eea017d869ef7b9af28d8dc04 200 Gene3D G3DSA:3.40.30.10 5 161 4.7E-62 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS13095 9665b4e2bda48e002b1e3e5b6ec2ce3e 214 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 66 181 1.4E-7 T 11-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 AUP74_RS13095 9665b4e2bda48e002b1e3e5b6ec2ce3e 214 Gene3D G3DSA:3.40.50.1000 68 209 7.1E-40 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS13095 9665b4e2bda48e002b1e3e5b6ec2ce3e 214 Pfam PF13419 Haloacid dehalogenase-like hydrolase 3 181 1.6E-29 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS13095 9665b4e2bda48e002b1e3e5b6ec2ce3e 214 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 98 173 4.4E-8 T 11-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 AUP74_RS13095 9665b4e2bda48e002b1e3e5b6ec2ce3e 214 Gene3D G3DSA:1.10.150.240 18 67 8.8E-12 T 11-11-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 AUP74_RS13095 9665b4e2bda48e002b1e3e5b6ec2ce3e 214 SUPERFAMILY SSF56784 2 209 5.7E-52 T 11-11-2016 IPR023214 HAD-like domain AUP74_RS06340 9404dc4c0f51526904811031251f612c 163 SUPERFAMILY SSF55083 1 156 5.36E-43 T 11-11-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AUP74_RS06340 9404dc4c0f51526904811031251f612c 163 Gene3D G3DSA:3.30.70.560 3 152 2.2E-39 T 11-11-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AUP74_RS06340 9404dc4c0f51526904811031251f612c 163 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 130 1.3E-25 T 11-11-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AUP74_RS06340 9404dc4c0f51526904811031251f612c 163 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 130 3.4E-26 T 11-11-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AUP74_RS14925 0b5142bdfb6ab6951123781985bb5410 250 SUPERFAMILY SSF53335 9 234 2.74E-39 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS14925 0b5142bdfb6ab6951123781985bb5410 250 Gene3D G3DSA:3.40.50.150 8 234 1.5E-42 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS14925 0b5142bdfb6ab6951123781985bb5410 250 Pfam PF08241 Methyltransferase domain 18 119 9.0E-24 T 11-11-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 AUP74_RS01635 a7121389c89f6c088cb2b3e4aa5244bf 405 Pfam PF13679 Methyltransferase domain 114 237 1.1E-14 T 11-11-2016 IPR025714 Methyltransferase domain AUP74_RS01635 a7121389c89f6c088cb2b3e4aa5244bf 405 SUPERFAMILY SSF53335 105 189 1.07E-5 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS13965 bcb830edc9bdb56b22e1fc14cb2f95b2 464 Pfam PF03553 Na+/H+ antiporter family 159 461 2.9E-53 T 11-11-2016 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 AUP74_RS02225 ef8795f0522e4c4fdf4b47e9cce054d6 276 Pfam PF06258 Mitochondrial fission ELM1 29 270 2.4E-48 T 11-11-2016 IPR009367 Mitochondrial fission protein ELM1-like AUP74_RS03635 60eebd3cc7c4b439bd74db56fe52fc44 260 SUPERFAMILY SSF56925 23 43 2.07E-28 T 11-11-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AUP74_RS03635 60eebd3cc7c4b439bd74db56fe52fc44 260 SUPERFAMILY SSF56925 77 108 2.07E-28 T 11-11-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AUP74_RS03635 60eebd3cc7c4b439bd74db56fe52fc44 260 SUPERFAMILY SSF56925 147 260 2.07E-28 T 11-11-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AUP74_RS03635 60eebd3cc7c4b439bd74db56fe52fc44 260 Gene3D G3DSA:2.40.160.20 23 42 2.3E-32 T 11-11-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AUP74_RS03635 60eebd3cc7c4b439bd74db56fe52fc44 260 Gene3D G3DSA:2.40.160.20 76 114 2.3E-32 T 11-11-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AUP74_RS03635 60eebd3cc7c4b439bd74db56fe52fc44 260 Gene3D G3DSA:2.40.160.20 153 260 2.3E-32 T 11-11-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AUP74_RS03635 60eebd3cc7c4b439bd74db56fe52fc44 260 Pfam PF13505 Outer membrane protein beta-barrel domain 10 240 1.4E-15 T 11-11-2016 IPR027385 Outer membrane protein beta-barrel AUP74_RS15760 d7c6beaa2f75ab515cfbd428dde91756 99 SUPERFAMILY SSF54909 1 97 2.25E-30 T 11-11-2016 IPR011008 Dimeric alpha-beta barrel AUP74_RS15760 d7c6beaa2f75ab515cfbd428dde91756 99 Gene3D G3DSA:3.30.70.1060 1 97 7.8E-35 T 11-11-2016 AUP74_RS15760 d7c6beaa2f75ab515cfbd428dde91756 99 Pfam PF03795 YCII-related domain 1 95 1.5E-28 T 11-11-2016 IPR005545 YCII-related AUP74_RS03335 493475a11a059fbd709f813134069f57 1046 Pfam PF01555 DNA methylase 487 817 8.0E-26 T 11-11-2016 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 AUP74_RS03335 493475a11a059fbd709f813134069f57 1046 SUPERFAMILY SSF53335 728 833 1.08E-38 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS03335 493475a11a059fbd709f813134069f57 1046 SUPERFAMILY SSF53335 458 644 1.08E-38 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS03335 493475a11a059fbd709f813134069f57 1046 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 487 499 1.7E-7 T 11-11-2016 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 AUP74_RS03335 493475a11a059fbd709f813134069f57 1046 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 521 540 1.7E-7 T 11-11-2016 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 AUP74_RS03335 493475a11a059fbd709f813134069f57 1046 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 780 794 1.7E-7 T 11-11-2016 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 AUP74_RS03335 493475a11a059fbd709f813134069f57 1046 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 490 496 - T 11-11-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 AUP74_RS03335 493475a11a059fbd709f813134069f57 1046 Gene3D G3DSA:3.40.50.150 466 606 4.0E-41 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS03335 493475a11a059fbd709f813134069f57 1046 Gene3D G3DSA:3.40.50.150 659 828 4.0E-41 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS06035 b60ea1ec2b7dfdbcb8a4d5e21cf7d30f 328 Hamap MF_01497 Stress response kinase A [srkA]. 4 319 48.166 T 11-11-2016 IPR032882 SrkA/RdoA protein kinase GO:0004674|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 AUP74_RS06035 b60ea1ec2b7dfdbcb8a4d5e21cf7d30f 328 SUPERFAMILY SSF56112 5 324 3.52E-91 T 11-11-2016 IPR011009 Protein kinase-like domain AUP74_RS06035 b60ea1ec2b7dfdbcb8a4d5e21cf7d30f 328 Pfam PF01636 Phosphotransferase enzyme family 35 257 7.8E-37 T 11-11-2016 IPR002575 Aminoglycoside phosphotransferase AUP74_RS06035 b60ea1ec2b7dfdbcb8a4d5e21cf7d30f 328 Gene3D G3DSA:3.90.1200.10 109 323 1.5E-45 T 11-11-2016 AUP74_RS13320 252fadc06920744b95bd3005a8a0f36f 271 SUPERFAMILY SSF56534 11 256 1.57E-99 T 11-11-2016 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 AUP74_RS13320 252fadc06920744b95bd3005a8a0f36f 271 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 83 105 8.2E-10 T 11-11-2016 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 AUP74_RS13320 252fadc06920744b95bd3005a8a0f36f 271 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 147 166 8.2E-10 T 11-11-2016 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 AUP74_RS13320 252fadc06920744b95bd3005a8a0f36f 271 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 187 205 8.2E-10 T 11-11-2016 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 AUP74_RS13320 252fadc06920744b95bd3005a8a0f36f 271 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 218 237 8.2E-10 T 11-11-2016 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 AUP74_RS13320 252fadc06920744b95bd3005a8a0f36f 271 TIGRFAM TIGR01267 Phe4hydrox_mono: phenylalanine-4-hydroxylase 20 263 4.8E-104 T 11-11-2016 IPR005960 Phenylalanine-4-hydroxylase, monomeric form GO:0004505|GO:0006559|GO:0055114 KEGG: 00360+1.14.16.1|KEGG: 00400+1.14.16.1|MetaCyc: PWY-6134|MetaCyc: PWY-7158 AUP74_RS13320 252fadc06920744b95bd3005a8a0f36f 271 Gene3D G3DSA:1.10.800.10 13 249 1.9E-93 T 11-11-2016 IPR001273 Aromatic amino acid hydroxylase GO:0004497|GO:0005506|GO:0009072|GO:0055114 AUP74_RS13320 252fadc06920744b95bd3005a8a0f36f 271 ProSitePatterns PS00367 Biopterin-dependent aromatic amino acid hydroxylases signature. 126 137 - T 11-11-2016 IPR018301 Aromatic amino acid hydroxylase, iron/copper binding site GO:0004497|GO:0005506|GO:0009072|GO:0055114 AUP74_RS13320 252fadc06920744b95bd3005a8a0f36f 271 Pfam PF00351 Biopterin-dependent aromatic amino acid hydroxylase 25 242 3.3E-51 T 11-11-2016 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 AUP74_RS04730 e34f95a40834c6e30289b8d4e3a1bc15 223 Pfam PF02630 SCO1/SenC 54 199 6.4E-36 T 11-11-2016 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AUP74_RS04730 e34f95a40834c6e30289b8d4e3a1bc15 223 Gene3D G3DSA:3.40.30.10 23 211 2.3E-53 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS04730 e34f95a40834c6e30289b8d4e3a1bc15 223 SUPERFAMILY SSF52833 59 210 4.23E-46 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS01540 f244f1e74f215dcc0d700bce4025c73a 146 Pfam PF01029 NusB family 9 132 2.4E-33 T 11-11-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 AUP74_RS01540 f244f1e74f215dcc0d700bce4025c73a 146 Gene3D G3DSA:1.10.940.10 7 140 3.9E-43 T 11-11-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 AUP74_RS01540 f244f1e74f215dcc0d700bce4025c73a 146 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 6 137 21.986 T 11-11-2016 IPR011605 NusB antitermination factor GO:0006353 AUP74_RS01540 f244f1e74f215dcc0d700bce4025c73a 146 SUPERFAMILY SSF48013 6 137 9.16E-42 T 11-11-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 AUP74_RS01540 f244f1e74f215dcc0d700bce4025c73a 146 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 8 134 6.0E-42 T 11-11-2016 IPR011605 NusB antitermination factor GO:0006353 AUP74_RS06250 1ea95b9609b945e22aec3746f42ef41e 125 Pfam PF05656 Protein of unknown function (DUF805) 11 118 1.4E-34 T 11-11-2016 IPR008523 Protein of unknown function DUF805 GO:0016021 AUP74_RS05110 3dc647fe9d5e7edab73c3cff4cf98cfe 288 Pfam PF01263 Aldose 1-epimerase 6 162 3.9E-23 T 11-11-2016 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 AUP74_RS05110 3dc647fe9d5e7edab73c3cff4cf98cfe 288 Gene3D G3DSA:2.70.98.10 4 150 8.5E-20 T 11-11-2016 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 AUP74_RS05110 3dc647fe9d5e7edab73c3cff4cf98cfe 288 SUPERFAMILY SSF74650 4 286 4.9E-46 T 11-11-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 AUP74_RS06025 96970d5249ccae96c2befd4eb834a87b 123 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 115 4.0E-8 T 11-11-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AUP74_RS06025 96970d5249ccae96c2befd4eb834a87b 123 Gene3D G3DSA:3.10.180.10 1 118 1.9E-33 T 11-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AUP74_RS06025 96970d5249ccae96c2befd4eb834a87b 123 SUPERFAMILY SSF54593 2 121 3.03E-23 T 11-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AUP74_RS05755 6d71f46263adf827fd0c3619e8141475 363 Pfam PF01761 3-dehydroquinate synthase 68 326 2.6E-109 T 11-11-2016 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 AUP74_RS05755 6d71f46263adf827fd0c3619e8141475 363 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 2 359 43.491 T 11-11-2016 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 AUP74_RS05755 6d71f46263adf827fd0c3619e8141475 363 Gene3D G3DSA:1.20.1090.10 174 357 2.8E-68 T 11-11-2016 AUP74_RS05755 6d71f46263adf827fd0c3619e8141475 363 SUPERFAMILY SSF56796 4 357 2.09E-118 T 11-11-2016 AUP74_RS05755 6d71f46263adf827fd0c3619e8141475 363 PIRSF PIRSF001455 4 360 3.0E-106 T 11-11-2016 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 AUP74_RS05755 6d71f46263adf827fd0c3619e8141475 363 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 13 355 8.1E-115 T 11-11-2016 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 AUP74_RS05755 6d71f46263adf827fd0c3619e8141475 363 Gene3D G3DSA:3.40.50.1970 3 173 4.6E-69 T 11-11-2016 AUP74_RS01045 49e5d48c23c7635a6be8df407dff8d30 221 Pfam PF00849 RNA pseudouridylate synthase 21 167 1.2E-30 T 11-11-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS01045 49e5d48c23c7635a6be8df407dff8d30 221 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 58 72 - T 11-11-2016 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS01045 49e5d48c23c7635a6be8df407dff8d30 221 SUPERFAMILY SSF55120 6 215 6.88E-63 T 11-11-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 AUP74_RS07635 b942809ac5ae7e50b0487ea78aba74f6 522 SMART SM00028 145 178 380.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS07635 b942809ac5ae7e50b0487ea78aba74f6 522 SMART SM00028 339 372 12.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS07635 b942809ac5ae7e50b0487ea78aba74f6 522 SMART SM00028 287 320 34.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS07635 b942809ac5ae7e50b0487ea78aba74f6 522 SMART SM00028 235 268 33.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS07635 b942809ac5ae7e50b0487ea78aba74f6 522 SUPERFAMILY SSF48452 183 374 1.16E-11 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS07635 b942809ac5ae7e50b0487ea78aba74f6 522 Gene3D G3DSA:1.25.40.10 183 390 2.3E-13 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS05415 7a43d517dfc330080a2de1241785bc69 112 PIRSF PIRSF039144 1 112 8.8E-51 T 11-11-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AUP74_RS05415 7a43d517dfc330080a2de1241785bc69 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 11-11-2016 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 AUP74_RS05415 7a43d517dfc330080a2de1241785bc69 112 SUPERFAMILY SSF54913 1 112 6.67E-44 T 11-11-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta AUP74_RS05415 7a43d517dfc330080a2de1241785bc69 112 SMART SM00938 4 105 5.6E-63 T 11-11-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AUP74_RS05415 7a43d517dfc330080a2de1241785bc69 112 Gene3D G3DSA:3.30.70.120 1 112 8.4E-49 T 11-11-2016 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal AUP74_RS05415 7a43d517dfc330080a2de1241785bc69 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 3.3E-41 T 11-11-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AUP74_RS05415 7a43d517dfc330080a2de1241785bc69 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 11-11-2016 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 AUP74_RS05415 7a43d517dfc330080a2de1241785bc69 112 PRINTS PR00340 P-II protein signature 83 103 1.2E-40 T 11-11-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AUP74_RS05415 7a43d517dfc330080a2de1241785bc69 112 PRINTS PR00340 P-II protein signature 23 41 1.2E-40 T 11-11-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AUP74_RS05415 7a43d517dfc330080a2de1241785bc69 112 PRINTS PR00340 P-II protein signature 2 17 1.2E-40 T 11-11-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AUP74_RS05415 7a43d517dfc330080a2de1241785bc69 112 PRINTS PR00340 P-II protein signature 52 75 1.2E-40 T 11-11-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AUP74_RS08255 de2a007d516afc59cfa7c07575450b1f 228 Pfam PF01712 Deoxynucleoside kinase 24 213 1.1E-39 T 11-11-2016 IPR031314 Deoxynucleoside kinase domain AUP74_RS08255 de2a007d516afc59cfa7c07575450b1f 228 SUPERFAMILY SSF52540 21 223 1.02E-45 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS08255 de2a007d516afc59cfa7c07575450b1f 228 PIRSF PIRSF000705 8 223 1.7E-57 T 11-11-2016 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 AUP74_RS08255 de2a007d516afc59cfa7c07575450b1f 228 Gene3D G3DSA:3.40.50.300 22 214 4.5E-46 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS07500 fc64eb114d13a8b3b97af78eda3ede2a 233 Gene3D G3DSA:2.60.120.10 12 115 3.2E-16 T 11-11-2016 IPR014710 RmlC-like jelly roll fold AUP74_RS07500 fc64eb114d13a8b3b97af78eda3ede2a 233 Pfam PF00027 Cyclic nucleotide-binding domain 46 115 1.4E-11 T 11-11-2016 IPR000595 Cyclic nucleotide-binding domain AUP74_RS07500 fc64eb114d13a8b3b97af78eda3ede2a 233 SMART SM00100 23 155 4.1E-5 T 11-11-2016 IPR000595 Cyclic nucleotide-binding domain AUP74_RS07500 fc64eb114d13a8b3b97af78eda3ede2a 233 SUPERFAMILY SSF51206 13 116 4.45E-16 T 11-11-2016 IPR018490 Cyclic nucleotide-binding-like AUP74_RS11875 745948c850fcfc321bb16d05106b0cd3 209 SUPERFAMILY SSF48498 80 207 5.0E-33 T 11-11-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AUP74_RS11875 745948c850fcfc321bb16d05106b0cd3 209 ProSitePatterns PS01081 TetR-type HTH domain signature. 22 53 - T 11-11-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AUP74_RS11875 745948c850fcfc321bb16d05106b0cd3 209 Gene3D G3DSA:1.10.357.10 3 206 5.2E-39 T 11-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 AUP74_RS11875 745948c850fcfc321bb16d05106b0cd3 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 4.0E-10 T 11-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AUP74_RS11875 745948c850fcfc321bb16d05106b0cd3 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 4.0E-10 T 11-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AUP74_RS11875 745948c850fcfc321bb16d05106b0cd3 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 56 2.4E-14 T 11-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AUP74_RS11875 745948c850fcfc321bb16d05106b0cd3 209 SUPERFAMILY SSF46689 4 74 3.64E-18 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS04815 5973de100a287a8ce8f83d4d88d06c8b 209 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 15 200 7.1E-73 T 11-11-2016 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 AUP74_RS04815 5973de100a287a8ce8f83d4d88d06c8b 209 Pfam PF01926 50S ribosome-binding GTPase 33 151 4.6E-19 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 AUP74_RS04815 5973de100a287a8ce8f83d4d88d06c8b 209 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 19 204 28.027 T 11-11-2016 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 AUP74_RS04815 5973de100a287a8ce8f83d4d88d06c8b 209 Gene3D G3DSA:3.40.50.300 23 204 6.5E-37 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS04815 5973de100a287a8ce8f83d4d88d06c8b 209 SUPERFAMILY SSF52540 21 205 1.11E-33 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS07300 1c331139d5de5c1ab490a85ea2265de9 234 SUPERFAMILY SSF103088 91 218 8.5E-11 T 11-11-2016 IPR006665 OmpA-like domain AUP74_RS07300 1c331139d5de5c1ab490a85ea2265de9 234 Gene3D G3DSA:3.30.1330.60 93 219 7.3E-14 T 11-11-2016 IPR006665 OmpA-like domain AUP74_RS14645 e7948efacb0854545eae842ebba33e50 294 SUPERFAMILY SSF54593 16 184 5.32E-7 T 11-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AUP74_RS14645 e7948efacb0854545eae842ebba33e50 294 Gene3D G3DSA:3.10.180.10 15 146 1.1E-5 T 11-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AUP74_RS15135 d6e7e15831b397b9b35935c731d834ac 326 TIGRFAM TIGR02249 integrase_gron: integron integrase 15 326 4.1E-126 T 11-11-2016 IPR011946 Integrase, integron-type GO:0003677|GO:0006310|GO:0015074 AUP74_RS15135 d6e7e15831b397b9b35935c731d834ac 326 Gene3D G3DSA:1.10.150.130 21 91 7.5E-5 T 11-11-2016 IPR023109 Integrase/recombinase, N-terminal AUP74_RS15135 d6e7e15831b397b9b35935c731d834ac 326 SUPERFAMILY SSF56349 16 319 1.88E-41 T 11-11-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AUP74_RS15135 d6e7e15831b397b9b35935c731d834ac 326 Gene3D G3DSA:1.10.443.10 114 314 5.0E-45 T 11-11-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 AUP74_RS15135 d6e7e15831b397b9b35935c731d834ac 326 Pfam PF00589 Phage integrase family 116 313 8.2E-40 T 11-11-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AUP74_RS15135 d6e7e15831b397b9b35935c731d834ac 326 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 15 97 1.9E-24 T 11-11-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 AUP74_RS00390 33c98710e191129796fbedcd19e9c225 304 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 211 8.4E-17 T 11-11-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 AUP74_RS00390 33c98710e191129796fbedcd19e9c225 304 Pfam PF08338 Domain of unknown function (DUF1731) 246 293 3.0E-18 T 11-11-2016 IPR013549 Domain of unknown function DUF1731 AUP74_RS00390 33c98710e191129796fbedcd19e9c225 304 Gene3D G3DSA:3.40.50.720 1 246 2.7E-25 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS00390 33c98710e191129796fbedcd19e9c225 304 SUPERFAMILY SSF51735 1 296 2.52E-44 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS00390 33c98710e191129796fbedcd19e9c225 304 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 4 290 3.4E-96 T 11-11-2016 IPR010099 Epimerase family protein SDR39U1 AUP74_RS14800 ad5e001e24c7abfd5c2cbfdac971646c 233 Hamap MF_00238 Cytidylate kinase [cmk]. 9 227 33.963 T 11-11-2016 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 AUP74_RS14800 ad5e001e24c7abfd5c2cbfdac971646c 233 Pfam PF02224 Cytidylate kinase 11 224 1.0E-74 T 11-11-2016 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 AUP74_RS14800 ad5e001e24c7abfd5c2cbfdac971646c 233 Gene3D G3DSA:3.40.50.300 8 224 1.1E-74 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS14800 ad5e001e24c7abfd5c2cbfdac971646c 233 SUPERFAMILY SSF52540 8 226 2.22E-46 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS14800 ad5e001e24c7abfd5c2cbfdac971646c 233 TIGRFAM TIGR00017 cmk: cytidylate kinase 9 222 3.8E-79 T 11-11-2016 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 AUP74_RS15895 7275faf18e2c3b531671142fdba07d09 94 SUPERFAMILY SSF82771 4 75 3.53E-10 T 11-11-2016 IPR000305 GIY-YIG nuclease superfamily AUP74_RS15895 7275faf18e2c3b531671142fdba07d09 94 Pfam PF01541 GIY-YIG catalytic domain 4 77 5.9E-14 T 11-11-2016 IPR000305 GIY-YIG nuclease superfamily AUP74_RS03935 776e3344a42f42628ce6e371ca59cf23 329 PIRSF PIRSF003097 31 325 2.5E-62 T 11-11-2016 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 AUP74_RS03935 776e3344a42f42628ce6e371ca59cf23 329 Pfam PF02687 FtsX-like permease family 206 318 3.3E-8 T 11-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 AUP74_RS16315 adc67bd871cc17de294c99b6c35d0d6d 225 Pfam PF01564 Spermine/spermidine synthase 89 181 2.7E-6 T 11-11-2016 AUP74_RS16315 adc67bd871cc17de294c99b6c35d0d6d 225 SUPERFAMILY SSF53335 45 219 6.67E-28 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS16315 adc67bd871cc17de294c99b6c35d0d6d 225 Gene3D G3DSA:3.40.50.150 61 204 4.6E-24 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS03410 4791b68df737a29f72e24f3278183c70 59 Pfam PF13551 Winged helix-turn helix 11 58 4.8E-12 T 11-11-2016 AUP74_RS03410 4791b68df737a29f72e24f3278183c70 59 Gene3D G3DSA:1.10.10.60 22 41 1.9E-4 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS05895 b4644c9e753907d6d82a4070817bd1ec 228 SUPERFAMILY SSF49354 22 126 1.13E-10 T 11-11-2016 IPR008962 PapD-like AUP74_RS05895 b4644c9e753907d6d82a4070817bd1ec 228 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 29 124 1.5E-5 T 11-11-2016 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 AUP74_RS05895 b4644c9e753907d6d82a4070817bd1ec 228 Gene3D G3DSA:2.60.40.360 36 121 4.2E-4 T 11-11-2016 IPR008962 PapD-like AUP74_RS11910 4f46e46867d1f698644b20a235eb8e45 491 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 139 300 1.2E-39 T 11-11-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS11910 4f46e46867d1f698644b20a235eb8e45 491 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 298 305 - T 11-11-2016 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS11910 4f46e46867d1f698644b20a235eb8e45 491 Gene3D G3DSA:3.30.360.10 309 464 3.9E-57 T 11-11-2016 AUP74_RS11910 4f46e46867d1f698644b20a235eb8e45 491 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 140 474 3.8E-114 T 11-11-2016 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS11910 4f46e46867d1f698644b20a235eb8e45 491 SUPERFAMILY SSF55347 300 463 3.27E-57 T 11-11-2016 AUP74_RS11910 4f46e46867d1f698644b20a235eb8e45 491 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 258 271 6.2E-18 T 11-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS11910 4f46e46867d1f698644b20a235eb8e45 491 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 294 312 6.2E-18 T 11-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS11910 4f46e46867d1f698644b20a235eb8e45 491 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 377 394 6.2E-18 T 11-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS11910 4f46e46867d1f698644b20a235eb8e45 491 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 321 337 6.2E-18 T 11-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS11910 4f46e46867d1f698644b20a235eb8e45 491 SMART SM00846 138 300 1.9E-51 T 11-11-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS11910 4f46e46867d1f698644b20a235eb8e45 491 Gene3D G3DSA:3.40.50.720 139 308 8.4E-50 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS11910 4f46e46867d1f698644b20a235eb8e45 491 SUPERFAMILY SSF51735 139 316 7.89E-43 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS11910 4f46e46867d1f698644b20a235eb8e45 491 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 305 462 5.6E-49 T 11-11-2016 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AUP74_RS01195 4422cc65866e728f40b938513b4f8606 304 Pfam PF08907 Domain of unknown function (DUF1853) 16 284 1.4E-58 T 11-11-2016 IPR015003 Protein of unknown function DUF1853 AUP74_RS11455 71b6cd33b3927d980bfeb30bccc76ea8 562 Pfam PF08774 VRR-NUC domain 454 559 9.9E-24 T 11-11-2016 IPR014883 VRR-NUC domain GO:0016788 Reactome: R-HSA-6783310 AUP74_RS11455 71b6cd33b3927d980bfeb30bccc76ea8 562 SMART SM00990 446 559 5.0E-30 T 11-11-2016 IPR014883 VRR-NUC domain GO:0016788 Reactome: R-HSA-6783310 AUP74_RS09700 11b5599cb7f2d3f4fa2e5ab2db59ef3a 88 Pfam PF13670 Peptidase propeptide and YPEB domain 7 84 3.4E-16 T 11-11-2016 IPR025711 PepSY domain AUP74_RS13045 6e0c6e76af58853517b40c7dcba9254b 338 Pfam PF02618 YceG-like family 36 320 1.6E-83 T 11-11-2016 IPR003770 Uncharacterised protein family UPF0755, YceG-like AUP74_RS13045 6e0c6e76af58853517b40c7dcba9254b 338 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 6 322 2.4E-81 T 11-11-2016 IPR003770 Uncharacterised protein family UPF0755, YceG-like AUP74_RS13045 6e0c6e76af58853517b40c7dcba9254b 338 Gene3D G3DSA:3.30.160.60 294 328 3.9E-18 T 11-11-2016 IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain GO:0003676 AUP74_RS02680 b6c403396780f0e5d03ebf5caf08f6eb 122 Pfam PF08000 Bacterial PH domain 15 119 1.3E-33 T 11-11-2016 IPR012544 Bacterial Pleckstrin homology domain AUP74_RS02680 b6c403396780f0e5d03ebf5caf08f6eb 122 Gene3D G3DSA:2.30.29.50 12 97 2.4E-31 T 11-11-2016 IPR012544 Bacterial Pleckstrin homology domain AUP74_RS02680 b6c403396780f0e5d03ebf5caf08f6eb 122 SUPERFAMILY SSF50729 17 122 4.3E-34 T 11-11-2016 IPR011993 PH domain-like AUP74_RS06645 d629842063c9e5f087430a8bebf822e4 467 Pfam PF01551 Peptidase family M23 320 414 7.2E-33 T 11-11-2016 IPR016047 Peptidase M23 AUP74_RS06645 d629842063c9e5f087430a8bebf822e4 467 Gene3D G3DSA:2.70.70.10 277 419 1.9E-47 T 11-11-2016 AUP74_RS06645 d629842063c9e5f087430a8bebf822e4 467 SUPERFAMILY SSF51261 171 416 6.28E-71 T 11-11-2016 IPR011055 Duplicated hybrid motif AUP74_RS06645 d629842063c9e5f087430a8bebf822e4 467 Pfam PF04225 Opacity-associated protein A LysM-like domain 94 177 4.5E-10 T 11-11-2016 IPR007340 Opacity-associated protein A AUP74_RS15450 c8a3bc258baa77f29469f41bfc7aa6db 196 SMART SM00987 28 185 4.4E-34 T 11-11-2016 AUP74_RS15450 c8a3bc258baa77f29469f41bfc7aa6db 196 SMART SM00986 28 185 4.4E-34 T 11-11-2016 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AUP74_RS15450 c8a3bc258baa77f29469f41bfc7aa6db 196 Gene3D G3DSA:3.40.470.10 7 193 2.9E-46 T 11-11-2016 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AUP74_RS15450 c8a3bc258baa77f29469f41bfc7aa6db 196 SUPERFAMILY SSF52141 7 191 2.62E-59 T 11-11-2016 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AUP74_RS15450 c8a3bc258baa77f29469f41bfc7aa6db 196 Pfam PF03167 Uracil DNA glycosylase superfamily 32 184 2.0E-26 T 11-11-2016 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AUP74_RS14090 9dc3079fbadedab446356d7ab3ce0e03 278 SUPERFAMILY SSF53474 41 144 9.23E-5 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS11890 13c08aacd2e3a5059587d079a2ccc378 71 PIRSF PIRSF002599 1 71 6.4E-23 T 11-11-2016 IPR012156 Cold shock, CspA GO:0003676 AUP74_RS11890 13c08aacd2e3a5059587d079a2ccc378 71 Pfam PF00313 'Cold-shock' DNA-binding domain 5 68 1.3E-27 T 11-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AUP74_RS11890 13c08aacd2e3a5059587d079a2ccc378 71 Gene3D G3DSA:2.40.50.140 5 68 4.6E-28 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS11890 13c08aacd2e3a5059587d079a2ccc378 71 PRINTS PR00050 Cold shock protein signature 43 61 2.1E-17 T 11-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AUP74_RS11890 13c08aacd2e3a5059587d079a2ccc378 71 PRINTS PR00050 Cold shock protein signature 7 22 2.1E-17 T 11-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AUP74_RS11890 13c08aacd2e3a5059587d079a2ccc378 71 PRINTS PR00050 Cold shock protein signature 28 37 2.1E-17 T 11-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AUP74_RS11890 13c08aacd2e3a5059587d079a2ccc378 71 SMART SM00357 6 70 1.7E-24 T 11-11-2016 IPR011129 Cold shock protein GO:0003676 AUP74_RS11890 13c08aacd2e3a5059587d079a2ccc378 71 SUPERFAMILY SSF50249 3 69 3.43E-24 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS11890 13c08aacd2e3a5059587d079a2ccc378 71 ProSitePatterns PS00352 'Cold-shock' domain signature. 18 37 - T 11-11-2016 IPR019844 Cold-shock conserved site AUP74_RS10525 cc9d79ed70a66b78ac31ba3d596524e1 77 Pfam PF01206 Sulfurtransferase TusA 5 74 3.3E-26 T 11-11-2016 IPR001455 TusA-like domain AUP74_RS10525 cc9d79ed70a66b78ac31ba3d596524e1 77 Gene3D G3DSA:3.30.110.40 1 74 4.6E-29 T 11-11-2016 IPR001455 TusA-like domain AUP74_RS10525 cc9d79ed70a66b78ac31ba3d596524e1 77 SUPERFAMILY SSF64307 3 74 2.75E-25 T 11-11-2016 IPR001455 TusA-like domain AUP74_RS10525 cc9d79ed70a66b78ac31ba3d596524e1 77 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 7 31 - T 11-11-2016 IPR001455 TusA-like domain AUP74_RS10860 23e0928f2d70b79af26784794bdc500b 114 Gene3D G3DSA:3.30.750.24 14 113 2.7E-12 T 11-11-2016 IPR002645 STAS domain AUP74_RS10860 23e0928f2d70b79af26784794bdc500b 114 SUPERFAMILY SSF52091 14 113 1.96E-15 T 11-11-2016 IPR002645 STAS domain AUP74_RS01055 718ab317c908cfb67a4e59b2514cb1b0 409 Pfam PF12704 MacB-like periplasmic core domain 19 252 8.4E-34 T 11-11-2016 IPR025857 MacB-like periplasmic core domain AUP74_RS01055 718ab317c908cfb67a4e59b2514cb1b0 409 Pfam PF02687 FtsX-like permease family 290 402 8.5E-20 T 11-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 AUP74_RS05425 d7df48b69f56d241cfe7a5945af8f043 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 11-11-2016 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 AUP74_RS05425 d7df48b69f56d241cfe7a5945af8f043 112 PRINTS PR00340 P-II protein signature 83 103 2.4E-43 T 11-11-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AUP74_RS05425 d7df48b69f56d241cfe7a5945af8f043 112 PRINTS PR00340 P-II protein signature 2 17 2.4E-43 T 11-11-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AUP74_RS05425 d7df48b69f56d241cfe7a5945af8f043 112 PRINTS PR00340 P-II protein signature 52 75 2.4E-43 T 11-11-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AUP74_RS05425 d7df48b69f56d241cfe7a5945af8f043 112 PRINTS PR00340 P-II protein signature 23 41 2.4E-43 T 11-11-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AUP74_RS05425 d7df48b69f56d241cfe7a5945af8f043 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 3.2E-43 T 11-11-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AUP74_RS05425 d7df48b69f56d241cfe7a5945af8f043 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 11-11-2016 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 AUP74_RS05425 d7df48b69f56d241cfe7a5945af8f043 112 SUPERFAMILY SSF54913 1 112 1.84E-45 T 11-11-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta AUP74_RS05425 d7df48b69f56d241cfe7a5945af8f043 112 Gene3D G3DSA:3.30.70.120 1 112 8.4E-51 T 11-11-2016 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal AUP74_RS05425 d7df48b69f56d241cfe7a5945af8f043 112 PIRSF PIRSF039144 1 112 2.9E-55 T 11-11-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AUP74_RS05425 d7df48b69f56d241cfe7a5945af8f043 112 SMART SM00938 4 105 4.0E-67 T 11-11-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AUP74_RS00555 23d23a7818ca635b14233a75c40d9ba6 328 PRINTS PR01805 VacJ lipoprotein signature 203 220 8.3E-26 T 11-11-2016 IPR007428 MlaA lipoprotein GO:0016020 AUP74_RS00555 23d23a7818ca635b14233a75c40d9ba6 328 PRINTS PR01805 VacJ lipoprotein signature 115 131 8.3E-26 T 11-11-2016 IPR007428 MlaA lipoprotein GO:0016020 AUP74_RS00555 23d23a7818ca635b14233a75c40d9ba6 328 PRINTS PR01805 VacJ lipoprotein signature 98 111 8.3E-26 T 11-11-2016 IPR007428 MlaA lipoprotein GO:0016020 AUP74_RS00555 23d23a7818ca635b14233a75c40d9ba6 328 PRINTS PR01805 VacJ lipoprotein signature 166 183 8.3E-26 T 11-11-2016 IPR007428 MlaA lipoprotein GO:0016020 AUP74_RS00555 23d23a7818ca635b14233a75c40d9ba6 328 Pfam PF04333 MlaA lipoprotein 97 287 2.0E-72 T 11-11-2016 IPR007428 MlaA lipoprotein GO:0016020 AUP74_RS00890 8baee486839740fcea404bd44c1040ac 226 PIRSF PIRSF006293 2 225 1.4E-82 T 11-11-2016 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 AUP74_RS00890 8baee486839740fcea404bd44c1040ac 226 Pfam PF06508 Queuosine biosynthesis protein QueC 5 215 4.3E-82 T 11-11-2016 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 AUP74_RS00890 8baee486839740fcea404bd44c1040ac 226 SUPERFAMILY SSF52402 4 223 8.6E-68 T 11-11-2016 AUP74_RS00890 8baee486839740fcea404bd44c1040ac 226 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 6 208 3.8E-65 T 11-11-2016 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 AUP74_RS00890 8baee486839740fcea404bd44c1040ac 226 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 4 221 58.079 T 11-11-2016 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 AUP74_RS00890 8baee486839740fcea404bd44c1040ac 226 Gene3D G3DSA:3.40.50.620 4 223 2.6E-84 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS04925 a53012580b09fbcbdd2baa264aa86d37 543 Pfam PF01523 Putative modulator of DNA gyrase 59 384 1.6E-53 T 11-11-2016 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 AUP74_RS04925 a53012580b09fbcbdd2baa264aa86d37 543 SUPERFAMILY SSF111283 42 536 1.06E-95 T 11-11-2016 AUP74_RS00060 35d8c852fad35a89d7b1bd58f01ca2a2 178 Pfam PF01641 SelR domain 55 172 5.1E-45 T 11-11-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 AUP74_RS00060 35d8c852fad35a89d7b1bd58f01ca2a2 178 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 53 173 1.7E-44 T 11-11-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 AUP74_RS00060 35d8c852fad35a89d7b1bd58f01ca2a2 178 Gene3D G3DSA:2.170.150.20 51 173 9.0E-49 T 11-11-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 AUP74_RS00060 35d8c852fad35a89d7b1bd58f01ca2a2 178 SUPERFAMILY SSF51316 51 173 5.75E-48 T 11-11-2016 IPR011057 Mss4-like AUP74_RS01645 39618da17c10499a0c5645e4856499d9 182 Pfam PF00578 AhpC/TSA family 12 134 1.3E-17 T 11-11-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AUP74_RS01645 39618da17c10499a0c5645e4856499d9 182 SUPERFAMILY SSF52833 5 182 1.66E-52 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS01645 39618da17c10499a0c5645e4856499d9 182 Gene3D G3DSA:3.40.30.10 11 174 7.1E-34 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS07860 835a04241ca674c6933acd845137f79d 346 Pfam PF13795 HupE / UreJ protein 150 301 2.4E-47 T 11-11-2016 IPR032809 Putative HupE/UreJ protein AUP74_RS04090 90496366f7c6cfbc9ebd90288945cac4 88 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 59 3.5E-25 T 11-11-2016 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS04090 90496366f7c6cfbc9ebd90288945cac4 88 Pfam PF01192 RNA polymerase Rpb6 8 59 6.2E-17 T 11-11-2016 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 AUP74_RS04090 90496366f7c6cfbc9ebd90288945cac4 88 SUPERFAMILY SSF63562 1 69 3.01E-25 T 11-11-2016 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 AUP74_RS04090 90496366f7c6cfbc9ebd90288945cac4 88 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 62 17.588 T 11-11-2016 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AUP74_RS04090 90496366f7c6cfbc9ebd90288945cac4 88 SMART SM01409 8 61 3.1E-17 T 11-11-2016 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 AUP74_RS04090 90496366f7c6cfbc9ebd90288945cac4 88 Gene3D G3DSA:3.90.940.10 1 71 1.7E-17 T 11-11-2016 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 AUP74_RS16275 36f9029fd5d042b3f41c1dea9ee48422 434 SUPERFAMILY SSF48208 29 419 5.67E-84 T 11-11-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 AUP74_RS16275 36f9029fd5d042b3f41c1dea9ee48422 434 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 42 381 6.2E-33 T 11-11-2016 AUP74_RS16275 36f9029fd5d042b3f41c1dea9ee48422 434 Hamap MF_00929 Cellobiose 2-epimerase. 15 413 38.283 T 11-11-2016 IPR028584 Cellobiose 2-epimerase GO:0047736 MetaCyc: PWY-7456 AUP74_RS16275 36f9029fd5d042b3f41c1dea9ee48422 434 Gene3D G3DSA:1.50.10.10 20 416 1.4E-106 T 11-11-2016 IPR012341 Six-hairpin glycosidase GO:0003824 AUP74_RS02165 63872095242aba3935ca9e17aae5ed4b 205 Pfam PF13590 Domain of unknown function (DUF4136) 53 204 3.7E-14 T 11-11-2016 IPR025411 Domain of unknown function DUF4136 AUP74_RS10575 a443802e1c1b7fa72b28f63428da3f5e 253 Pfam PF07386 Protein of unknown function (DUF1499) 105 242 6.5E-30 T 11-11-2016 IPR010865 Protein of unknown function DUF1499 AUP74_RS13580 fc4469296b24d05b52a8ed601c15b69a 787 Pfam PF02687 FtsX-like permease family 664 777 5.0E-15 T 11-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 AUP74_RS13580 fc4469296b24d05b52a8ed601c15b69a 787 Pfam PF02687 FtsX-like permease family 273 389 9.9E-17 T 11-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 AUP74_RS10760 6ff1292923cc4b4189aeff4be964ae3c 202 Pfam PF03458 UPF0126 domain 85 158 2.7E-18 T 11-11-2016 IPR005115 Uncharacterised domain UPF0126 AUP74_RS10760 6ff1292923cc4b4189aeff4be964ae3c 202 Pfam PF03458 UPF0126 domain 2 70 1.5E-16 T 11-11-2016 IPR005115 Uncharacterised domain UPF0126 AUP74_RS05350 d542a6666fe76fdc1d28ac1fbf4dbb91 661 SMART SM00635 46 131 2.5E-8 T 11-11-2016 IPR003343 Bacterial Ig-like, group 2 AUP74_RS05350 d542a6666fe76fdc1d28ac1fbf4dbb91 661 Gene3D G3DSA:2.60.40.1080 51 132 3.3E-5 T 11-11-2016 AUP74_RS14540 7714e4cdd092456e0a7aaa7686427bfa 570 SUPERFAMILY SSF56317 4 284 1.44E-49 T 11-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AUP74_RS14540 7714e4cdd092456e0a7aaa7686427bfa 570 SUPERFAMILY SSF56317 316 497 4.97E-17 T 11-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AUP74_RS14540 7714e4cdd092456e0a7aaa7686427bfa 570 Gene3D G3DSA:3.60.110.10 317 488 8.1E-15 T 11-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AUP74_RS14540 7714e4cdd092456e0a7aaa7686427bfa 570 Gene3D G3DSA:3.60.110.10 4 285 6.9E-52 T 11-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AUP74_RS14540 7714e4cdd092456e0a7aaa7686427bfa 570 Pfam PF00795 Carbon-nitrogen hydrolase 7 262 1.2E-33 T 11-11-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 AUP74_RS16725 fb9bf2e4af394e05b86d12be579de6e7 241 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 7 233 17.844 T 11-11-2016 IPR026579 Cell division protein FtsQ GO:0090529 AUP74_RS16725 fb9bf2e4af394e05b86d12be579de6e7 241 Pfam PF03799 Cell division protein FtsQ 112 225 3.5E-10 T 11-11-2016 IPR005548 Cell division protein FtsQ/DivIB AUP74_RS16725 fb9bf2e4af394e05b86d12be579de6e7 241 Pfam PF08478 POTRA domain, FtsQ-type 41 107 3.2E-14 T 11-11-2016 IPR013685 Polypeptide-transport-associated, FtsQ-type AUP74_RS16200 20a289ca6ca53aecdfcdf2b4cdf35ed8 441 Pfam PF10011 Predicted membrane protein (DUF2254) 13 388 2.0E-118 T 11-11-2016 IPR018723 Protein of unknown function DUF2254, membrane AUP74_RS08965 b94aae73adcec962fc1508b815b77680 244 Pfam PF03707 Bacterial signalling protein N terminal repeat 116 170 2.6E-17 T 11-11-2016 IPR005330 MHYT domain AUP74_RS08965 b94aae73adcec962fc1508b815b77680 244 Pfam PF03707 Bacterial signalling protein N terminal repeat 53 105 6.6E-17 T 11-11-2016 IPR005330 MHYT domain AUP74_RS10825 e13e8345f06dd573d594b24ea3c79b9d 372 SUPERFAMILY SSF51556 127 352 1.45E-17 T 11-11-2016 IPR032466 Metal-dependent hydrolase AUP74_RS10825 e13e8345f06dd573d594b24ea3c79b9d 372 Gene3D G3DSA:3.20.20.140 36 352 1.5E-21 T 11-11-2016 AUP74_RS10825 e13e8345f06dd573d594b24ea3c79b9d 372 Pfam PF04909 Amidohydrolase 173 351 3.5E-13 T 11-11-2016 IPR006680 Amidohydrolase-related GO:0016787 AUP74_RS09230 6ceef393a6b0a930cb56ec232a327f28 152 Gene3D G3DSA:1.20.1260.10 3 133 7.7E-6 T 11-11-2016 IPR012347 Ferritin-related AUP74_RS15955 2c254d315e5f21c38d2cf025ceeb0eb4 127 Pfam PF03413 Peptidase propeptide and YPEB domain 71 126 1.3E-7 T 11-11-2016 IPR025711 PepSY domain AUP74_RS12485 ccacec068e864e230a02e081911ebc6d 265 Pfam PF04784 Protein of unknown function, DUF547 74 184 7.8E-29 T 11-11-2016 IPR006869 Domain of unknown function DUF547 AUP74_RS10130 4465daf09599e509c77e142e495bc021 1001 Pfam PF11739 Dicarboxylate transport 795 995 1.1E-40 T 11-11-2016 IPR021730 Dicarboxylate transport AUP74_RS01295 8b16d5d5d6e560d656a52a40f2de8d92 232 SUPERFAMILY SSF51182 2 228 1.0E-70 T 11-11-2016 IPR011051 RmlC-like cupin domain AUP74_RS01295 8b16d5d5d6e560d656a52a40f2de8d92 232 Gene3D G3DSA:2.60.120.10 4 228 1.4E-64 T 11-11-2016 IPR014710 RmlC-like jelly roll fold AUP74_RS01295 8b16d5d5d6e560d656a52a40f2de8d92 232 Pfam PF02678 Pirin 13 119 1.3E-34 T 11-11-2016 IPR003829 Pirin, N-terminal domain AUP74_RS01295 8b16d5d5d6e560d656a52a40f2de8d92 232 PIRSF PIRSF006232 1 227 1.1E-51 T 11-11-2016 IPR012093 Pirin AUP74_RS15410 42d596b06e9aff73e9b4fea456fc0a55 352 Pfam PF03888 MucB/RseB N-terminal domain 74 237 1.1E-38 T 11-11-2016 IPR033434 MucB/RseB, N-terminal AUP74_RS15410 42d596b06e9aff73e9b4fea456fc0a55 352 Gene3D G3DSA:2.50.20.10 159 224 2.0E-4 T 11-11-2016 AUP74_RS15410 42d596b06e9aff73e9b4fea456fc0a55 352 Pfam PF17188 MucB/RseB C-terminal domain 255 347 2.5E-16 T 11-11-2016 IPR033436 MucB/RseB, C-terminal AUP74_RS15410 42d596b06e9aff73e9b4fea456fc0a55 352 PIRSF PIRSF005427 54 351 1.8E-61 T 11-11-2016 IPR005588 MucB/RseB AUP74_RS02605 aafbdde8c6dcea6e2a4b68fbf795fca0 187 SUPERFAMILY SSF53271 3 166 1.56E-25 T 11-11-2016 IPR029057 Phosphoribosyltransferase-like AUP74_RS02605 aafbdde8c6dcea6e2a4b68fbf795fca0 187 Pfam PF00156 Phosphoribosyl transferase domain 10 161 2.2E-10 T 11-11-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 AUP74_RS02605 aafbdde8c6dcea6e2a4b68fbf795fca0 187 Gene3D G3DSA:3.40.50.2020 3 175 3.1E-24 T 11-11-2016 IPR029057 Phosphoribosyltransferase-like AUP74_RS10055 72e0f1538739ff172b5dcfedabd86fb9 242 Pfam PF01965 DJ-1/PfpI family 40 236 1.7E-15 T 11-11-2016 IPR002818 DJ-1/PfpI AUP74_RS10055 72e0f1538739ff172b5dcfedabd86fb9 242 SUPERFAMILY SSF52317 19 238 2.79E-71 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS10055 72e0f1538739ff172b5dcfedabd86fb9 242 Gene3D G3DSA:3.40.50.880 14 240 4.6E-88 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS02485 34349b6e667815a72504385609a536ad 210 SUPERFAMILY SSF53955 14 168 3.8E-19 T 11-11-2016 IPR023346 Lysozyme-like domain AUP74_RS02485 34349b6e667815a72504385609a536ad 210 Gene3D G3DSA:1.10.530.10 50 189 9.6E-10 T 11-11-2016 AUP74_RS07140 920e062459a6b9e8f97704a32862c787 178 Pfam PF14341 PilX N-terminal 8 55 1.5E-9 T 11-11-2016 IPR025746 Type 4 fimbrial biogenesis protein PilX, N-terminal domain AUP74_RS15725 4c3f47073c49e71a492bf90c7306135f 240 Gene3D G3DSA:3.30.530.20 27 171 1.1E-12 T 11-11-2016 IPR023393 START-like domain AUP74_RS15725 4c3f47073c49e71a492bf90c7306135f 240 SUPERFAMILY SSF55961 27 172 4.81E-20 T 11-11-2016 AUP74_RS15725 4c3f47073c49e71a492bf90c7306135f 240 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 27 171 8.8E-22 T 11-11-2016 IPR019587 Polyketide cyclase/dehydrase AUP74_RS04190 5cfe0152a70c963b0dfd9304979113d3 233 Gene3D G3DSA:1.20.58.220 8 118 4.3E-33 T 11-11-2016 AUP74_RS04190 5cfe0152a70c963b0dfd9304979113d3 233 Gene3D G3DSA:1.20.58.220 126 224 7.4E-31 T 11-11-2016 AUP74_RS04190 5cfe0152a70c963b0dfd9304979113d3 233 Pfam PF01895 PhoU domain 25 111 4.5E-22 T 11-11-2016 IPR026022 PhoU domain AUP74_RS04190 5cfe0152a70c963b0dfd9304979113d3 233 Pfam PF01895 PhoU domain 128 212 3.4E-15 T 11-11-2016 IPR026022 PhoU domain AUP74_RS04190 5cfe0152a70c963b0dfd9304979113d3 233 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 11 221 2.6E-71 T 11-11-2016 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 AUP74_RS04190 5cfe0152a70c963b0dfd9304979113d3 233 PIRSF PIRSF003107 6 227 1.1E-69 T 11-11-2016 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 AUP74_RS04190 5cfe0152a70c963b0dfd9304979113d3 233 SUPERFAMILY SSF109755 11 229 1.05E-69 T 11-11-2016 AUP74_RS03850 27732fccc75ceb996e4f0f5a14fd6190 257 SUPERFAMILY SSF50199 29 156 5.36E-29 T 11-11-2016 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold AUP74_RS03850 27732fccc75ceb996e4f0f5a14fd6190 257 ProSitePatterns PS01284 Thermonuclease family signature 2. 95 105 - T 11-11-2016 IPR002071 Thermonuclease active site GO:0003676|GO:0004518 AUP74_RS03850 27732fccc75ceb996e4f0f5a14fd6190 257 SMART SM00318 25 154 2.0E-23 T 11-11-2016 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold AUP74_RS03850 27732fccc75ceb996e4f0f5a14fd6190 257 Pfam PF00565 Staphylococcal nuclease homologue 48 153 2.5E-19 T 11-11-2016 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold AUP74_RS03850 27732fccc75ceb996e4f0f5a14fd6190 257 Gene3D G3DSA:2.40.50.90 30 155 2.4E-23 T 11-11-2016 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold AUP74_RS01235 13bc212d7797604e989ab57804e4ab8d 85 Pfam PF04325 Protein of unknown function (DUF465) 29 74 1.4E-10 T 11-11-2016 IPR007420 Protein of unknown function DUF465 AUP74_RS01070 8f118885b8d6dc96a1ca2b4ffa69af77 320 Pfam PF13437 HlyD family secretion protein 194 301 3.6E-7 T 11-11-2016 AUP74_RS12070 e7301a3457af51c66af6734fa3ab5e38 392 SUPERFAMILY SSF54506 186 391 1.18E-76 T 11-11-2016 AUP74_RS12070 e7301a3457af51c66af6734fa3ab5e38 392 Gene3D G3DSA:3.10.310.10 194 370 1.8E-78 T 11-11-2016 AUP74_RS12070 e7301a3457af51c66af6734fa3ab5e38 392 Pfam PF04303 PrpF protein 6 388 1.3E-177 T 11-11-2016 IPR007400 PrpF protein AUP74_RS12070 e7301a3457af51c66af6734fa3ab5e38 392 SUPERFAMILY SSF54506 2 182 5.18E-72 T 11-11-2016 AUP74_RS12070 e7301a3457af51c66af6734fa3ab5e38 392 TIGRFAM TIGR02334 prpF: probable AcnD-accessory protein PrpF 5 392 2.3E-234 T 11-11-2016 IPR012709 2-methyl-aconitate isomerase PrpF GO:0016853|GO:0019629 AUP74_RS12070 e7301a3457af51c66af6734fa3ab5e38 392 Gene3D G3DSA:3.10.310.10 2 193 7.2E-93 T 11-11-2016 AUP74_RS13485 9555b940b11caa5b837935ad4c870275 109 Gene3D G3DSA:3.30.780.10 30 109 2.4E-33 T 11-11-2016 IPR001950 Translation initiation factor SUI1 GO:0003743|GO:0006413 AUP74_RS13485 9555b940b11caa5b837935ad4c870275 109 PIRSF PIRSF037511 1 109 1.7E-35 T 11-11-2016 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 AUP74_RS13485 9555b940b11caa5b837935ad4c870275 109 TIGRFAM TIGR01158 SUI1_rel: putative translation initiation factor SUI1 9 109 9.0E-35 T 11-11-2016 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 AUP74_RS13485 9555b940b11caa5b837935ad4c870275 109 Pfam PF01253 Translation initiation factor SUI1 33 103 8.0E-19 T 11-11-2016 IPR001950 Translation initiation factor SUI1 GO:0003743|GO:0006413 AUP74_RS13485 9555b940b11caa5b837935ad4c870275 109 SUPERFAMILY SSF55159 8 105 1.44E-24 T 11-11-2016 IPR001950 Translation initiation factor SUI1 GO:0003743|GO:0006413 AUP74_RS13130 105709be9fb2e73adb2d6aa93cd29d53 266 SUPERFAMILY SSF56935 80 243 1.14E-5 T 11-11-2016 AUP74_RS13130 105709be9fb2e73adb2d6aa93cd29d53 266 Pfam PF09694 Bacterial protein of unknown function (Gcw_chp) 50 262 3.6E-30 T 11-11-2016 IPR010239 Conserved hypothetical protein CHP02001 AUP74_RS13130 105709be9fb2e73adb2d6aa93cd29d53 266 TIGRFAM TIGR02001 gcw_chp: conserved hypothetical protein 52 266 4.1E-40 T 11-11-2016 IPR010239 Conserved hypothetical protein CHP02001 AUP74_RS16430 fd93d83bd1d6eec821bd2e82c4981886 153 Pfam PF07813 LTXXQ motif family protein 42 135 3.5E-11 T 11-11-2016 IPR012899 LTXXQ motif family protein GO:0042597 AUP74_RS00080 7380db7e3c57e52e538e06460f87a595 159 PIRSF PIRSF018472 1 159 1.1E-45 T 11-11-2016 IPR026034 Cell shape-determining protein MreD, proteobacterial type AUP74_RS00080 7380db7e3c57e52e538e06460f87a595 159 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 5 151 3.6E-33 T 11-11-2016 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 AUP74_RS00080 7380db7e3c57e52e538e06460f87a595 159 Pfam PF04093 rod shape-determining protein MreD 4 149 6.6E-19 T 11-11-2016 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 AUP74_RS02380 22f25e19e137067a8300f809bcdd4867 388 Pfam PF09375 Imelysin 60 366 3.0E-23 T 11-11-2016 AUP74_RS13530 9c18886f671dd1d9a43265cbd392dc03 491 Pfam PF01235 Sodium:alanine symporter family 68 472 1.6E-149 T 11-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AUP74_RS13530 9c18886f671dd1d9a43265cbd392dc03 491 TIGRFAM TIGR00835 agcS: amino acid carrier protein 31 459 1.8E-139 T 11-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AUP74_RS13530 9c18886f671dd1d9a43265cbd392dc03 491 PRINTS PR00175 Sodium/alanine symporter signature 103 125 8.9E-59 T 11-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AUP74_RS13530 9c18886f671dd1d9a43265cbd392dc03 491 PRINTS PR00175 Sodium/alanine symporter signature 225 244 8.9E-59 T 11-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AUP74_RS13530 9c18886f671dd1d9a43265cbd392dc03 491 PRINTS PR00175 Sodium/alanine symporter signature 361 383 8.9E-59 T 11-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AUP74_RS13530 9c18886f671dd1d9a43265cbd392dc03 491 PRINTS PR00175 Sodium/alanine symporter signature 316 334 8.9E-59 T 11-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AUP74_RS13530 9c18886f671dd1d9a43265cbd392dc03 491 PRINTS PR00175 Sodium/alanine symporter signature 428 448 8.9E-59 T 11-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AUP74_RS13530 9c18886f671dd1d9a43265cbd392dc03 491 PRINTS PR00175 Sodium/alanine symporter signature 197 215 8.9E-59 T 11-11-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AUP74_RS04100 caab236126d1efdb7e65a68c28550b40 127 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 5 126 1.4E-50 T 11-11-2016 IPR006056 RidA family AUP74_RS04100 caab236126d1efdb7e65a68c28550b40 127 Gene3D G3DSA:3.30.1330.40 6 124 1.2E-47 T 11-11-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like AUP74_RS04100 caab236126d1efdb7e65a68c28550b40 127 Pfam PF01042 Endoribonuclease L-PSP 10 126 2.8E-42 T 11-11-2016 IPR006175 YjgF/YER057c/UK114 family AUP74_RS04100 caab236126d1efdb7e65a68c28550b40 127 SUPERFAMILY SSF55298 5 127 1.57E-45 T 11-11-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like AUP74_RS16675 cfccb0d0836c354736ff41fff05a6b57 294 Pfam PF01478 Type IV leader peptidase family 140 248 1.2E-24 T 11-11-2016 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 AUP74_RS16675 cfccb0d0836c354736ff41fff05a6b57 294 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 148 165 1.9E-25 T 11-11-2016 IPR014032 Peptidase A24A, prepilin type IV, bacterial AUP74_RS16675 cfccb0d0836c354736ff41fff05a6b57 294 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 228 243 1.9E-25 T 11-11-2016 IPR014032 Peptidase A24A, prepilin type IV, bacterial AUP74_RS16675 cfccb0d0836c354736ff41fff05a6b57 294 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 216 227 1.9E-25 T 11-11-2016 IPR014032 Peptidase A24A, prepilin type IV, bacterial AUP74_RS16675 cfccb0d0836c354736ff41fff05a6b57 294 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 205 215 1.9E-25 T 11-11-2016 IPR014032 Peptidase A24A, prepilin type IV, bacterial AUP74_RS16675 cfccb0d0836c354736ff41fff05a6b57 294 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 18 128 3.3E-33 T 11-11-2016 IPR010627 Peptidase A24A, N-terminal AUP74_RS11605 faea4a85415883ebd52d813fa51239c0 276 Pfam PF13835 Domain of unknown function (DUF4194) 25 201 1.8E-31 T 11-11-2016 IPR025449 Protein of unknown function DUF4194 AUP74_RS00200 22c9a3ecc5a961247679eff022bed2cc 202 Gene3D G3DSA:3.40.50.1470 7 196 2.4E-70 T 11-11-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 AUP74_RS00200 22c9a3ecc5a961247679eff022bed2cc 202 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 10 194 7.4E-61 T 11-11-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 AUP74_RS00200 22c9a3ecc5a961247679eff022bed2cc 202 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 9 188 35.076 T 11-11-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 AUP74_RS00200 22c9a3ecc5a961247679eff022bed2cc 202 SUPERFAMILY SSF53178 9 195 9.81E-68 T 11-11-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 AUP74_RS00200 22c9a3ecc5a961247679eff022bed2cc 202 Pfam PF01195 Peptidyl-tRNA hydrolase 11 192 1.0E-53 T 11-11-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 AUP74_RS00200 22c9a3ecc5a961247679eff022bed2cc 202 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 116 126 - T 11-11-2016 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 AUP74_RS02860 f11d86e26fd8ffeb407a02716b9402fe 220 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 18 208 6.9E-52 T 11-11-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 AUP74_RS02860 f11d86e26fd8ffeb407a02716b9402fe 220 Gene3D G3DSA:3.90.850.10 15 209 9.7E-70 T 11-11-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 AUP74_RS02860 f11d86e26fd8ffeb407a02716b9402fe 220 SUPERFAMILY SSF56529 14 209 3.92E-64 T 11-11-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 AUP74_RS05270 3d2d518f8e8f7ab85a1b17c57ca29890 355 Pfam PF17186 Lipocalin-like domain 233 353 4.7E-37 T 11-11-2016 IPR033451 AttH, lipocalin-like domain AUP74_RS05270 3d2d518f8e8f7ab85a1b17c57ca29890 355 Gene3D G3DSA:2.40.370.10 235 353 1.8E-36 T 11-11-2016 IPR023374 AttH-like domain AUP74_RS05270 3d2d518f8e8f7ab85a1b17c57ca29890 355 Gene3D G3DSA:2.40.370.10 48 233 6.0E-66 T 11-11-2016 IPR023374 AttH-like domain AUP74_RS05270 3d2d518f8e8f7ab85a1b17c57ca29890 355 SUPERFAMILY SSF159245 37 353 9.81E-94 T 11-11-2016 AUP74_RS05270 3d2d518f8e8f7ab85a1b17c57ca29890 355 Pfam PF07143 CrtC N-terminal lipocalin domain 61 230 6.4E-51 T 11-11-2016 IPR010791 AttH domain AUP74_RS14590 90da1ff49e0dc0de301b9d69f8fde967 403 Gene3D G3DSA:3.40.50.10540 7 213 1.8E-102 T 11-11-2016 IPR023606 CoA-transferase family III domain AUP74_RS14590 90da1ff49e0dc0de301b9d69f8fde967 403 Gene3D G3DSA:3.40.50.10540 303 395 1.8E-102 T 11-11-2016 IPR023606 CoA-transferase family III domain AUP74_RS14590 90da1ff49e0dc0de301b9d69f8fde967 403 Gene3D G3DSA:3.30.1540.10 219 302 1.3E-21 T 11-11-2016 AUP74_RS14590 90da1ff49e0dc0de301b9d69f8fde967 403 SUPERFAMILY SSF89796 5 393 8.37E-125 T 11-11-2016 IPR023606 CoA-transferase family III domain AUP74_RS14590 90da1ff49e0dc0de301b9d69f8fde967 403 Pfam PF02515 CoA-transferase family III 9 369 1.3E-117 T 11-11-2016 IPR003673 CoA-transferase family III GO:0003824 AUP74_RS08835 7eddad3c5e9b52753d5c2282e80f3e3e 283 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 81 263 8.5E-10 T 11-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase AUP74_RS08835 7eddad3c5e9b52753d5c2282e80f3e3e 283 Gene3D G3DSA:3.60.10.10 63 268 1.7E-8 T 11-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase AUP74_RS08835 7eddad3c5e9b52753d5c2282e80f3e3e 283 SUPERFAMILY SSF56219 61 271 4.32E-20 T 11-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase AUP74_RS02185 50fd012e8c6b80f986020042c15f8552 222 Pfam PF04403 Paraquat-inducible protein A 53 205 3.9E-39 T 11-11-2016 IPR007498 Paraquat-inducible protein A AUP74_RS00695 25a70ad5c4e2b01a3fcce41e5a6c0c11 194 Pfam PF01914 MarC family integral membrane protein 5 192 4.6E-50 T 11-11-2016 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 AUP74_RS06690 dc22c5fcadab61f6c816c0b264bacd4f 469 SUPERFAMILY SSF53474 341 426 7.74E-28 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS06690 dc22c5fcadab61f6c816c0b264bacd4f 469 SUPERFAMILY SSF53474 236 296 7.74E-28 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS06690 dc22c5fcadab61f6c816c0b264bacd4f 469 SUPERFAMILY SSF53474 35 107 7.74E-28 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS06690 dc22c5fcadab61f6c816c0b264bacd4f 469 SUPERFAMILY SSF53474 136 195 7.74E-28 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS06690 dc22c5fcadab61f6c816c0b264bacd4f 469 Pfam PF00561 alpha/beta hydrolase fold 62 411 5.5E-19 T 11-11-2016 IPR000073 Alpha/beta hydrolase fold-1 AUP74_RS06690 dc22c5fcadab61f6c816c0b264bacd4f 469 Gene3D G3DSA:3.40.50.1820 315 427 9.0E-42 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS06690 dc22c5fcadab61f6c816c0b264bacd4f 469 Gene3D G3DSA:3.40.50.1820 45 260 9.0E-42 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS06690 dc22c5fcadab61f6c816c0b264bacd4f 469 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 163 177 6.7E-7 T 11-11-2016 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 AUP74_RS06690 dc22c5fcadab61f6c816c0b264bacd4f 469 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 63 71 6.7E-7 T 11-11-2016 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 AUP74_RS06690 dc22c5fcadab61f6c816c0b264bacd4f 469 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 93 104 6.7E-7 T 11-11-2016 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 AUP74_RS14170 b1634e424ec32f4ec7214bce27f977c2 402 SUPERFAMILY SSF103365 16 402 3.4E-137 T 11-11-2016 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 AUP74_RS14170 b1634e424ec32f4ec7214bce27f977c2 402 Pfam PF01139 tRNA-splicing ligase RtcB 32 402 1.2E-136 T 11-11-2016 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 AUP74_RS03165 1015aecfe329334399f906e9e451efa0 157 Pfam PF03724 META domain 40 147 3.6E-18 T 11-11-2016 IPR005184 Domain of unknown function DUF306, Meta/HslJ AUP74_RS10700 e7dc813746422cd71d5f344ff3d4d0bf 403 Pfam PF00999 Sodium/hydrogen exchanger family 10 390 9.4E-41 T 11-11-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 AUP74_RS10700 e7dc813746422cd71d5f344ff3d4d0bf 403 PRINTS PR00173 Glutamate-aspartate symporter signature 339 358 3.7E-6 T 11-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AUP74_RS10700 e7dc813746422cd71d5f344ff3d4d0bf 403 PRINTS PR00173 Glutamate-aspartate symporter signature 91 111 3.7E-6 T 11-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AUP74_RS10700 e7dc813746422cd71d5f344ff3d4d0bf 403 PRINTS PR00173 Glutamate-aspartate symporter signature 184 209 3.7E-6 T 11-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AUP74_RS10700 e7dc813746422cd71d5f344ff3d4d0bf 403 PRINTS PR00173 Glutamate-aspartate symporter signature 376 395 3.7E-6 T 11-11-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AUP74_RS00400 1af48df1ab6801cb714a9a2390a54739 253 Pfam PF02698 DUF218 domain 73 238 2.3E-22 T 11-11-2016 IPR003848 Domain of unknown function DUF218 AUP74_RS00400 1af48df1ab6801cb714a9a2390a54739 253 Gene3D G3DSA:3.40.50.620 72 201 7.4E-24 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AUP74_RS05945 83235c60a75d15b808270dad07b7548c 146 Pfam PF01250 Ribosomal protein S6 3 91 5.8E-27 T 11-11-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS05945 83235c60a75d15b808270dad07b7548c 146 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 94 21.918 T 11-11-2016 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 AUP74_RS05945 83235c60a75d15b808270dad07b7548c 146 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 93 4.9E-34 T 11-11-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS05945 83235c60a75d15b808270dad07b7548c 146 ProSitePatterns PS01048 Ribosomal protein S6 signature. 43 52 - T 11-11-2016 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 AUP74_RS05945 83235c60a75d15b808270dad07b7548c 146 Gene3D G3DSA:3.30.70.60 1 104 7.8E-41 T 11-11-2016 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 AUP74_RS05945 83235c60a75d15b808270dad07b7548c 146 SUPERFAMILY SSF54995 1 103 1.83E-36 T 11-11-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS04830 2c741b7d796bbe67384ee8d31fd5cbe4 403 Gene3D G3DSA:1.10.760.10 137 174 7.5E-8 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS04830 2c741b7d796bbe67384ee8d31fd5cbe4 403 SUPERFAMILY SSF46626 136 173 2.26E-8 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS04830 2c741b7d796bbe67384ee8d31fd5cbe4 403 Pfam PF00034 Cytochrome c 138 169 3.7E-5 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 AUP74_RS05280 36b67784a37710cabb49463b1e616484 192 Pfam PF03942 DTW domain 3 186 2.9E-44 T 11-11-2016 IPR005636 DTW AUP74_RS05280 36b67784a37710cabb49463b1e616484 192 SMART SM01144 2 191 4.8E-56 T 11-11-2016 IPR005636 DTW AUP74_RS13585 374851325729de3218be488cd2f339bb 402 SUPERFAMILY SSF111369 201 257 4.05E-6 T 11-11-2016 AUP74_RS13585 374851325729de3218be488cd2f339bb 402 SUPERFAMILY SSF111369 88 174 4.05E-6 T 11-11-2016 AUP74_RS13585 374851325729de3218be488cd2f339bb 402 Pfam PF13437 HlyD family secretion protein 206 306 3.1E-10 T 11-11-2016 AUP74_RS13585 374851325729de3218be488cd2f339bb 402 Gene3D G3DSA:2.40.50.100 197 235 2.3E-6 T 11-11-2016 AUP74_RS13585 374851325729de3218be488cd2f339bb 402 Gene3D G3DSA:2.40.50.100 58 89 2.3E-6 T 11-11-2016 AUP74_RS01475 d54bf61dea7042530f787b8ecacb1539 191 Pfam PF14279 HNH endonuclease 94 147 1.1E-18 T 11-11-2016 IPR029471 HNH endonuclease 5 AUP74_RS01475 d54bf61dea7042530f787b8ecacb1539 191 SMART SM00507 81 134 3.2E-12 T 11-11-2016 IPR003615 HNH nuclease AUP74_RS02280 49ecd5713be63dd369e41a0e2ad87e53 287 Pfam PF00892 EamA-like transporter family 139 274 6.4E-7 T 11-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 AUP74_RS02280 49ecd5713be63dd369e41a0e2ad87e53 287 Pfam PF00892 EamA-like transporter family 3 128 4.0E-7 T 11-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 AUP74_RS02280 49ecd5713be63dd369e41a0e2ad87e53 287 SUPERFAMILY SSF103481 175 276 1.7E-7 T 11-11-2016 AUP74_RS02280 49ecd5713be63dd369e41a0e2ad87e53 287 TIGRFAM TIGR00950 2A78: carboxylate/amino acid/amine transporter 11 271 7.6E-70 T 11-11-2016 IPR004779 Carboxylate/Amino Acid/Amine Transporter GO:0016021 AUP74_RS02280 49ecd5713be63dd369e41a0e2ad87e53 287 SUPERFAMILY SSF103481 36 131 1.12E-5 T 11-11-2016 AUP74_RS13310 71326355ccc72d425dcb76f374ee7aae 108 Pfam PF06127 Protein of unknown function (DUF962) 12 105 1.7E-35 T 11-11-2016 IPR009305 Protein of unknown function DUF962 AUP74_RS14415 7515a3be9a92e3612d23c643a9e3e09a 222 SUPERFAMILY SSF52499 18 217 7.59E-40 T 11-11-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 AUP74_RS14415 7515a3be9a92e3612d23c643a9e3e09a 222 Gene3D G3DSA:3.40.50.850 7 219 3.9E-40 T 11-11-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 AUP74_RS14415 7515a3be9a92e3612d23c643a9e3e09a 222 Pfam PF00857 Isochorismatase family 31 212 7.5E-29 T 11-11-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 AUP74_RS06475 1225699a17a568629cb25258c5bf1a81 135 Pfam PF02566 OsmC-like protein 30 126 1.0E-14 T 11-11-2016 IPR003718 OsmC/Ohr family AUP74_RS06475 1225699a17a568629cb25258c5bf1a81 135 Gene3D G3DSA:2.20.25.10 1 32 1.3E-10 T 11-11-2016 AUP74_RS06475 1225699a17a568629cb25258c5bf1a81 135 Gene3D G3DSA:3.30.300.20 35 133 1.1E-35 T 11-11-2016 IPR015946 K homology domain-like, alpha/beta AUP74_RS06475 1225699a17a568629cb25258c5bf1a81 135 SUPERFAMILY SSF82784 1 130 3.4E-34 T 11-11-2016 IPR003718 OsmC/Ohr family AUP74_RS06400 93045385f9aa7ec8e90e6bf42b1fe575 358 SUPERFAMILY SSF56300 53 297 6.96E-28 T 11-11-2016 IPR029052 Metallo-dependent phosphatase-like AUP74_RS06400 93045385f9aa7ec8e90e6bf42b1fe575 358 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 1 273 5.4E-67 T 11-11-2016 IPR019079 Capsule synthesis protein, CapA AUP74_RS06400 93045385f9aa7ec8e90e6bf42b1fe575 358 Gene3D G3DSA:3.60.21.30 65 268 3.3E-13 T 11-11-2016 AUP74_RS06400 93045385f9aa7ec8e90e6bf42b1fe575 358 SMART SM00854 1 273 2.9E-87 T 11-11-2016 IPR019079 Capsule synthesis protein, CapA AUP74_RS04950 f7ee4a6f9421f41df9f82f3e0de61130 220 Pfam PF04012 PspA/IM30 family 5 218 2.7E-11 T 11-11-2016 IPR007157 PspA/IM30 AUP74_RS15415 e594c7041ae045c72baaa00602348cf3 212 Pfam PF03872 Anti sigma-E protein RseA, N-terminal domain 1 65 1.5E-9 T 11-11-2016 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 AUP74_RS15415 e594c7041ae045c72baaa00602348cf3 212 SUPERFAMILY SSF89069 1 60 4.05E-8 T 11-11-2016 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 AUP74_RS15750 d119b2739fb51f8d82076944cab44738 292 SMART SM00481 2 67 1.2E-21 T 11-11-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 AUP74_RS15750 d119b2739fb51f8d82076944cab44738 292 Pfam PF02811 PHP domain 3 66 2.4E-8 T 11-11-2016 IPR004013 PHP domain GO:0003824 AUP74_RS15750 d119b2739fb51f8d82076944cab44738 292 SUPERFAMILY SSF89550 2 80 4.51E-47 T 11-11-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AUP74_RS15750 d119b2739fb51f8d82076944cab44738 292 SUPERFAMILY SSF89550 162 280 4.51E-47 T 11-11-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AUP74_RS15750 d119b2739fb51f8d82076944cab44738 292 Gene3D G3DSA:3.20.20.140 2 85 5.5E-38 T 11-11-2016 AUP74_RS15750 d119b2739fb51f8d82076944cab44738 292 Gene3D G3DSA:3.20.20.140 154 273 5.5E-38 T 11-11-2016 AUP74_RS10155 7abf9d3994e563ae6606962d3fbd94ab 290 SUPERFAMILY SSF46785 2 77 4.14E-18 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS10155 7abf9d3994e563ae6606962d3fbd94ab 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 27 37 3.7E-9 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS10155 7abf9d3994e563ae6606962d3fbd94ab 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 48 3.7E-9 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS10155 7abf9d3994e563ae6606962d3fbd94ab 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 16 27 3.7E-9 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS10155 7abf9d3994e563ae6606962d3fbd94ab 290 Pfam PF03466 LysR substrate binding domain 89 287 4.3E-25 T 11-11-2016 IPR005119 LysR, substrate-binding AUP74_RS10155 7abf9d3994e563ae6606962d3fbd94ab 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 57 1.6E-17 T 11-11-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AUP74_RS10155 7abf9d3994e563ae6606962d3fbd94ab 290 Gene3D G3DSA:3.40.190.10 83 171 8.1E-28 T 11-11-2016 AUP74_RS10155 7abf9d3994e563ae6606962d3fbd94ab 290 Gene3D G3DSA:3.40.190.10 275 288 8.1E-28 T 11-11-2016 AUP74_RS10155 7abf9d3994e563ae6606962d3fbd94ab 290 SUPERFAMILY SSF53850 83 287 8.93E-45 T 11-11-2016 AUP74_RS10155 7abf9d3994e563ae6606962d3fbd94ab 290 Gene3D G3DSA:1.10.10.10 1 77 2.0E-26 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS10155 7abf9d3994e563ae6606962d3fbd94ab 290 Gene3D G3DSA:3.40.190.10 172 259 5.9E-28 T 11-11-2016 AUP74_RS15885 6ac4061e90a232e4fae608161eea3867 514 SUPERFAMILY SSF51395 19 487 5.37E-125 T 11-11-2016 AUP74_RS15885 6ac4061e90a232e4fae608161eea3867 514 Gene3D G3DSA:3.20.20.70 44 487 4.6E-116 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS15885 6ac4061e90a232e4fae608161eea3867 514 Pfam PF01645 Conserved region in glutamate synthase 151 471 8.8E-84 T 11-11-2016 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 AUP74_RS15885 6ac4061e90a232e4fae608161eea3867 514 PIRSF PIRSF006429 3 511 5.8E-156 T 11-11-2016 IPR024188 Glutamate synthase large subunit-like protein AUP74_RS01290 1aef0e4283647e2fd3a7ef47991a1206 231 Pfam PF01965 DJ-1/PfpI family 24 214 9.2E-17 T 11-11-2016 IPR002818 DJ-1/PfpI AUP74_RS01290 1aef0e4283647e2fd3a7ef47991a1206 231 SUPERFAMILY SSF52317 4 223 7.58E-68 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS01290 1aef0e4283647e2fd3a7ef47991a1206 231 Gene3D G3DSA:3.40.50.880 2 228 9.8E-82 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like AUP74_RS02970 e5cf64c0a9bf0802a711bd513c2baa0a 156 Pfam PF03942 DTW domain 3 138 6.7E-27 T 11-11-2016 IPR005636 DTW AUP74_RS02970 e5cf64c0a9bf0802a711bd513c2baa0a 156 SMART SM01144 1 156 1.4E-20 T 11-11-2016 IPR005636 DTW AUP74_RS05730 98b91e243afa6584f3cac4f477e17723 196 Pfam PF05137 Fimbrial assembly protein (PilN) 100 176 3.3E-22 T 11-11-2016 IPR007813 Fimbrial assembly PilN AUP74_RS02195 f56d5bd2d4ef2bb2762eb1574630da4b 429 SUPERFAMILY SSF53756 57 425 1.98E-17 T 11-11-2016 AUP74_RS02195 f56d5bd2d4ef2bb2762eb1574630da4b 429 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 33 214 1.2E-62 T 11-11-2016 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 AUP74_RS02195 f56d5bd2d4ef2bb2762eb1574630da4b 429 Gene3D G3DSA:3.40.50.2000 338 399 8.5E-4 T 11-11-2016 AUP74_RS02195 f56d5bd2d4ef2bb2762eb1574630da4b 429 Pfam PF00534 Glycosyl transferases group 1 252 405 1.2E-6 T 11-11-2016 IPR001296 Glycosyl transferase, family 1 AUP74_RS06260 cb5f80b4186ffc2e9823ba091648bb35 773 Gene3D G3DSA:2.170.130.10 78 187 1.4E-26 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS06260 cb5f80b4186ffc2e9823ba091648bb35 773 SUPERFAMILY SSF56935 48 773 8.77E-101 T 11-11-2016 AUP74_RS06260 cb5f80b4186ffc2e9823ba091648bb35 773 Pfam PF07715 TonB-dependent Receptor Plug Domain 82 180 1.0E-15 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS06260 cb5f80b4186ffc2e9823ba091648bb35 773 Gene3D G3DSA:2.40.170.20 196 773 2.7E-98 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS06260 cb5f80b4186ffc2e9823ba091648bb35 773 Pfam PF00593 TonB dependent receptor 517 771 6.0E-21 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS04960 218d7a0cffe4b125192e2861fd18fa60 554 SUPERFAMILY SSF117892 48 193 1.44E-23 T 11-11-2016 IPR001107 Band 7 domain AUP74_RS04960 218d7a0cffe4b125192e2861fd18fa60 554 SMART SM00244 17 186 1.4E-7 T 11-11-2016 IPR001107 Band 7 domain AUP74_RS04960 218d7a0cffe4b125192e2861fd18fa60 554 Pfam PF15975 Flotillin 415 543 2.1E-34 T 11-11-2016 IPR031905 Flotillin, C-terminal domain Reactome: R-HSA-8849932 AUP74_RS05435 591176222a0bd606d2d458e6390a6224 630 Pfam PF12228 Protein of unknown function (DUF3604) 45 630 6.9E-242 T 11-11-2016 IPR022028 Protein of unknown function DUF3604 AUP74_RS07395 a69b4e478f20e1ea60825cfd5d16c49f 158 Pfam PF10067 Predicted membrane protein (DUF2306) 8 147 1.1E-11 T 11-11-2016 IPR018750 Protein of unknown function DUF2306, membrane AUP74_RS15525 9a774188620467ca74832d37b3b5238e 575 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 23 570 5.7E-158 T 11-11-2016 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 AUP74_RS15525 9a774188620467ca74832d37b3b5238e 575 Pfam PF02272 DHHA1 domain 380 448 1.7E-15 T 11-11-2016 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 AUP74_RS15525 9a774188620467ca74832d37b3b5238e 575 Pfam PF01368 DHH family 72 207 4.8E-11 T 11-11-2016 IPR001667 DDH domain AUP74_RS15525 9a774188620467ca74832d37b3b5238e 575 SUPERFAMILY SSF64182 47 463 1.24E-120 T 11-11-2016 AUP74_RS14880 d312e75f9a4f0069763522f352b5d7b1 363 Pfam PF13439 Glycosyltransferase Family 4 17 166 3.0E-18 T 11-11-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AUP74_RS14880 d312e75f9a4f0069763522f352b5d7b1 363 Gene3D G3DSA:3.40.50.2000 192 337 8.4E-8 T 11-11-2016 AUP74_RS14880 d312e75f9a4f0069763522f352b5d7b1 363 SUPERFAMILY SSF53756 16 362 1.92E-45 T 11-11-2016 AUP74_RS14880 d312e75f9a4f0069763522f352b5d7b1 363 Pfam PF00534 Glycosyl transferases group 1 190 339 3.4E-19 T 11-11-2016 IPR001296 Glycosyl transferase, family 1 AUP74_RS16320 89811a57e02929858ebc57a7eed39e27 292 SUPERFAMILY SSF103481 40 138 1.57E-12 T 11-11-2016 AUP74_RS16320 89811a57e02929858ebc57a7eed39e27 292 Pfam PF00892 EamA-like transporter family 5 138 1.7E-15 T 11-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 AUP74_RS16320 89811a57e02929858ebc57a7eed39e27 292 Pfam PF00892 EamA-like transporter family 151 284 5.2E-17 T 11-11-2016 IPR000620 EamA domain GO:0016020|GO:0016021 AUP74_RS16320 89811a57e02929858ebc57a7eed39e27 292 SUPERFAMILY SSF103481 207 288 1.83E-14 T 11-11-2016 AUP74_RS16025 9be78f3063c872aa03b7bfa8f26a0d08 405 Gene3D G3DSA:1.20.1250.20 8 196 1.5E-9 T 11-11-2016 AUP74_RS16025 9be78f3063c872aa03b7bfa8f26a0d08 405 Gene3D G3DSA:1.20.1250.20 224 393 7.3E-13 T 11-11-2016 AUP74_RS16025 9be78f3063c872aa03b7bfa8f26a0d08 405 Pfam PF07690 Major Facilitator Superfamily 9 319 7.5E-15 T 11-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AUP74_RS16025 9be78f3063c872aa03b7bfa8f26a0d08 405 SUPERFAMILY SSF103473 8 395 1.57E-32 T 11-11-2016 IPR020846 Major facilitator superfamily domain AUP74_RS07575 5aadaa7a13490113f0577e37eb44be5b 127 Pfam PF07784 Protein of unknown function (DUF1622) 36 112 8.6E-25 T 11-11-2016 IPR012427 Protein of unknown function DUF1622 AUP74_RS02585 ae91a8b918ce08cd05cb14ac0683402c 90 Pfam PF14026 Protein of unknown function (DUF4242) 4 80 1.9E-28 T 11-11-2016 IPR025336 Protein of unknown function DUF4242 AUP74_RS11070 3ae31e8228ee35cc1e87ca98afb5be87 186 SUPERFAMILY SSF49764 71 182 6.98E-32 T 11-11-2016 IPR008978 HSP20-like chaperone AUP74_RS11070 3ae31e8228ee35cc1e87ca98afb5be87 186 Gene3D G3DSA:2.60.40.790 29 182 4.2E-34 T 11-11-2016 IPR008978 HSP20-like chaperone AUP74_RS11070 3ae31e8228ee35cc1e87ca98afb5be87 186 Pfam PF00011 Hsp20/alpha crystallin family 80 182 9.8E-20 T 11-11-2016 IPR002068 Alpha crystallin/Hsp20 domain AUP74_RS14860 5656f9c37f5605095ff2b249b96df653 225 Gene3D G3DSA:2.40.128.110 58 223 4.2E-11 T 11-11-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like AUP74_RS14860 5656f9c37f5605095ff2b249b96df653 225 Pfam PF04264 YceI-like domain 59 222 9.5E-6 T 11-11-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like AUP74_RS14860 5656f9c37f5605095ff2b249b96df653 225 SUPERFAMILY SSF101874 58 223 1.83E-12 T 11-11-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like AUP74_RS06995 fa557faff010c1a0f0a21de46b2a9837 194 SUPERFAMILY SSF50249 3 194 1.03E-58 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS06995 fa557faff010c1a0f0a21de46b2a9837 194 Gene3D G3DSA:2.40.50.140 1 124 1.5E-56 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS06995 fa557faff010c1a0f0a21de46b2a9837 194 Gene3D G3DSA:2.40.50.140 174 194 1.5E-56 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold AUP74_RS06995 fa557faff010c1a0f0a21de46b2a9837 194 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 194 2.5E-56 T 11-11-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 AUP74_RS06995 fa557faff010c1a0f0a21de46b2a9837 194 Pfam PF00436 Single-strand binding protein family 5 110 4.5E-43 T 11-11-2016 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 AUP74_RS06995 fa557faff010c1a0f0a21de46b2a9837 194 Hamap MF_00984 Single-stranded DNA-binding protein. 5 114 39.961 T 11-11-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 AUP74_RS10720 637ae233d0e9a86a91bd979aa9cdbe28 106 Gene3D G3DSA:3.30.70.900 3 84 8.0E-11 T 11-11-2016 AUP74_RS10720 637ae233d0e9a86a91bd979aa9cdbe28 106 SUPERFAMILY SSF54909 6 89 9.49E-12 T 11-11-2016 IPR011008 Dimeric alpha-beta barrel AUP74_RS10720 637ae233d0e9a86a91bd979aa9cdbe28 106 Pfam PF03992 Antibiotic biosynthesis monooxygenase 9 73 1.9E-8 T 11-11-2016 IPR007138 Antibiotic biosynthesis monooxygenase domain AUP74_RS02315 1ac2e9a0f2a7fb4724be0823b196734f 207 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 122 204 5.7E-12 T 11-11-2016 IPR006260 TonB, C-terminal GO:0006810 AUP74_RS02315 1ac2e9a0f2a7fb4724be0823b196734f 207 Gene3D G3DSA:3.30.1150.10 118 204 5.3E-4 T 11-11-2016 AUP74_RS02315 1ac2e9a0f2a7fb4724be0823b196734f 207 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 121 204 4.3E-15 T 11-11-2016 IPR006260 TonB, C-terminal GO:0006810 AUP74_RS02315 1ac2e9a0f2a7fb4724be0823b196734f 207 SUPERFAMILY SSF74653 112 196 7.98E-21 T 11-11-2016 AUP74_RS07295 cfb4cc6b2e53dfb269f73e710d324530 435 Pfam PF01618 MotA/TolQ/ExbB proton channel family 48 111 1.3E-5 T 11-11-2016 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 AUP74_RS08635 878d0e7a4c31c73c147338361274649f 208 Pfam PF10973 Protein of unknown function (DUF2799) 32 116 1.5E-24 T 11-11-2016 IPR021242 Protein of unknown function DUF2799 AUP74_RS08635 878d0e7a4c31c73c147338361274649f 208 ProDom PD042352 MG349 G12_ORF413 HOMOLOG 89 174 0.003 T 11-11-2016 AUP74_RS16785 d1ae181a225ea932c3a73cc1bb7ed940 264 Pfam PF13899 Thioredoxin-like 33 119 1.8E-7 T 11-11-2016 AUP74_RS16785 d1ae181a225ea932c3a73cc1bb7ed940 264 SUPERFAMILY SSF52833 38 126 3.68E-8 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS16785 d1ae181a225ea932c3a73cc1bb7ed940 264 Gene3D G3DSA:3.40.30.10 32 127 8.5E-14 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS07360 e2e9068bbdae39beff73882a05c990be 241 Pfam PF01925 Sulfite exporter TauE/SafE 3 237 1.9E-40 T 11-11-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 AUP74_RS08025 0ec6baf89e37c28fcf47e3fc8b47e5a0 300 SMART SM00849 46 229 1.0E-27 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS08025 0ec6baf89e37c28fcf47e3fc8b47e5a0 300 Pfam PF00753 Metallo-beta-lactamase superfamily 46 207 5.2E-17 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS08025 0ec6baf89e37c28fcf47e3fc8b47e5a0 300 SUPERFAMILY SSF56281 9 270 3.5E-54 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS08025 0ec6baf89e37c28fcf47e3fc8b47e5a0 300 Gene3D G3DSA:3.60.15.10 27 252 2.1E-49 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS06255 862c677d74c95a3e168984d436ba62bb 226 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 83 175 2.4E-14 T 11-11-2016 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 AUP74_RS06255 862c677d74c95a3e168984d436ba62bb 226 SMART SM00702 1 176 2.1E-13 T 11-11-2016 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 AUP74_RS06255 862c677d74c95a3e168984d436ba62bb 226 Hamap MF_00657 PKHD-type hydroxylase YbiX [ybiX]. 1 226 38.331 T 11-11-2016 IPR023550 PKHD-type hydroxylase GO:0016706|GO:0055114 AUP74_RS04460 d975b6f39351a40297837b333d539d99 145 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 11 119 2.0E-25 T 11-11-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 AUP74_RS04460 d975b6f39351a40297837b333d539d99 145 Pfam PF00825 Ribonuclease P 10 117 1.2E-27 T 11-11-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 AUP74_RS04460 d975b6f39351a40297837b333d539d99 145 Gene3D G3DSA:3.30.230.10 9 121 7.7E-30 T 11-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AUP74_RS04460 d975b6f39351a40297837b333d539d99 145 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 10 120 17.434 T 11-11-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 AUP74_RS04460 d975b6f39351a40297837b333d539d99 145 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 61 75 - T 11-11-2016 IPR020539 Ribonuclease P, conserved site GO:0004526 AUP74_RS04460 d975b6f39351a40297837b333d539d99 145 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 21 110 3.0E-21 T 11-11-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 AUP74_RS04460 d975b6f39351a40297837b333d539d99 145 SUPERFAMILY SSF54211 10 120 1.92E-26 T 11-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold AUP74_RS12635 947b1551248d315ba919345094848193 160 SMART SM00100 13 131 2.0E-6 T 11-11-2016 IPR000595 Cyclic nucleotide-binding domain AUP74_RS12635 947b1551248d315ba919345094848193 160 Gene3D G3DSA:2.60.120.10 5 145 1.8E-22 T 11-11-2016 IPR014710 RmlC-like jelly roll fold AUP74_RS12635 947b1551248d315ba919345094848193 160 Pfam PF00027 Cyclic nucleotide-binding domain 33 117 6.0E-12 T 11-11-2016 IPR000595 Cyclic nucleotide-binding domain AUP74_RS12635 947b1551248d315ba919345094848193 160 SUPERFAMILY SSF51206 6 134 2.23E-25 T 11-11-2016 IPR018490 Cyclic nucleotide-binding-like AUP74_RS05195 694ec96ba9858dce34f27be710e4b1b8 975 SUPERFAMILY SSF56935 688 732 2.63E-82 T 11-11-2016 AUP74_RS05195 694ec96ba9858dce34f27be710e4b1b8 975 SUPERFAMILY SSF56935 786 833 2.63E-82 T 11-11-2016 AUP74_RS05195 694ec96ba9858dce34f27be710e4b1b8 975 SUPERFAMILY SSF56935 35 252 2.63E-82 T 11-11-2016 AUP74_RS05195 694ec96ba9858dce34f27be710e4b1b8 975 SUPERFAMILY SSF56935 347 645 2.63E-82 T 11-11-2016 AUP74_RS05195 694ec96ba9858dce34f27be710e4b1b8 975 SUPERFAMILY SSF56935 869 975 2.63E-82 T 11-11-2016 AUP74_RS05195 694ec96ba9858dce34f27be710e4b1b8 975 Pfam PF00593 TonB dependent receptor 618 972 2.4E-21 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS05195 694ec96ba9858dce34f27be710e4b1b8 975 Gene3D G3DSA:2.170.130.10 64 193 3.0E-26 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS05195 694ec96ba9858dce34f27be710e4b1b8 975 Gene3D G3DSA:2.40.170.20 780 975 2.9E-65 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS05195 694ec96ba9858dce34f27be710e4b1b8 975 Gene3D G3DSA:2.40.170.20 329 731 2.9E-65 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS05195 694ec96ba9858dce34f27be710e4b1b8 975 Gene3D G3DSA:2.40.170.20 194 255 2.9E-65 T 11-11-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 AUP74_RS05195 694ec96ba9858dce34f27be710e4b1b8 975 Pfam PF07715 TonB-dependent Receptor Plug Domain 63 190 2.3E-17 T 11-11-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 AUP74_RS03870 5002b75888d7a023977b3e162cb295bf 200 PIRSF PIRSF011489 1 195 1.9E-49 T 11-11-2016 IPR007431 Acyl carrier protein phosphodiesterase GO:0006633|GO:0008770 KEGG: 00770+3.1.4.14|MetaCyc: PWY-6012 AUP74_RS03870 5002b75888d7a023977b3e162cb295bf 200 Pfam PF04336 Protein of unknown function, DUF479 81 184 2.6E-23 T 11-11-2016 IPR007431 Acyl carrier protein phosphodiesterase GO:0006633|GO:0008770 KEGG: 00770+3.1.4.14|MetaCyc: PWY-6012 AUP74_RS03775 03861a309ec0617e1f42c7a8bcb48a74 281 SMART SM00244 20 178 1.2E-53 T 11-11-2016 IPR001107 Band 7 domain AUP74_RS03775 03861a309ec0617e1f42c7a8bcb48a74 281 Pfam PF01145 SPFH domain / Band 7 family 24 195 2.6E-31 T 11-11-2016 IPR001107 Band 7 domain AUP74_RS03775 03861a309ec0617e1f42c7a8bcb48a74 281 PRINTS PR00721 Stomatin signature 27 49 4.4E-26 T 11-11-2016 IPR001972 Stomatin family GO:0016020 AUP74_RS03775 03861a309ec0617e1f42c7a8bcb48a74 281 PRINTS PR00721 Stomatin signature 130 153 4.4E-26 T 11-11-2016 IPR001972 Stomatin family GO:0016020 AUP74_RS03775 03861a309ec0617e1f42c7a8bcb48a74 281 PRINTS PR00721 Stomatin signature 75 96 4.4E-26 T 11-11-2016 IPR001972 Stomatin family GO:0016020 AUP74_RS03775 03861a309ec0617e1f42c7a8bcb48a74 281 PRINTS PR00721 Stomatin signature 110 127 4.4E-26 T 11-11-2016 IPR001972 Stomatin family GO:0016020 AUP74_RS03775 03861a309ec0617e1f42c7a8bcb48a74 281 PRINTS PR00721 Stomatin signature 154 172 4.4E-26 T 11-11-2016 IPR001972 Stomatin family GO:0016020 AUP74_RS03775 03861a309ec0617e1f42c7a8bcb48a74 281 PRINTS PR00721 Stomatin signature 173 194 4.4E-26 T 11-11-2016 IPR001972 Stomatin family GO:0016020 AUP74_RS03775 03861a309ec0617e1f42c7a8bcb48a74 281 SUPERFAMILY SSF117892 51 185 2.35E-39 T 11-11-2016 IPR001107 Band 7 domain AUP74_RS11015 36cf2fc93dfe31c67bc0bbc4fba65ca9 145 Pfam PF06146 Phosphate-starvation-inducible E 69 136 2.6E-17 T 11-11-2016 IPR020948 Phosphate-starvation-induced PsiE-like AUP74_RS06575 6516b6708906a118683e96b4f9b33905 117 SUPERFAMILY SSF46785 20 115 3.9E-31 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS06575 6516b6708906a118683e96b4f9b33905 117 Gene3D G3DSA:1.10.10.10 6 115 8.2E-39 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain AUP74_RS06575 6516b6708906a118683e96b4f9b33905 117 Pfam PF01638 HxlR-like helix-turn-helix 30 115 2.3E-26 T 11-11-2016 IPR002577 Helix-turn-helix, HxlR type AUP74_RS13975 8762debb10aebf4c31632dfb577787e3 514 Pfam PF00144 Beta-lactamase 26 362 8.6E-66 T 11-11-2016 IPR001466 Beta-lactamase-related AUP74_RS13975 8762debb10aebf4c31632dfb577787e3 514 SUPERFAMILY SSF56601 22 372 3.13E-82 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS13975 8762debb10aebf4c31632dfb577787e3 514 Pfam PF11954 Domain of unknown function (DUF3471) 416 508 6.8E-10 T 11-11-2016 IPR021860 Peptidase S12, Pab87-related, C-terminal AUP74_RS13975 8762debb10aebf4c31632dfb577787e3 514 Gene3D G3DSA:3.40.710.10 11 371 9.4E-83 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS02000 ba4db4f58412ca7c1c157dd2880bd0b1 273 Pfam PF03239 Iron permease FTR1 family 3 242 1.6E-9 T 11-11-2016 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0006827|GO:0016020|GO:0033573 AUP74_RS00290 82f6a56ad9293525412b8265b53c1655 438 Pfam PF07690 Major Facilitator Superfamily 23 394 2.9E-11 T 11-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AUP74_RS00290 82f6a56ad9293525412b8265b53c1655 438 Gene3D G3DSA:1.20.1250.20 21 216 2.6E-15 T 11-11-2016 AUP74_RS00290 82f6a56ad9293525412b8265b53c1655 438 SUPERFAMILY SSF103473 12 430 3.92E-29 T 11-11-2016 IPR020846 Major facilitator superfamily domain AUP74_RS00290 82f6a56ad9293525412b8265b53c1655 438 TIGRFAM TIGR01272 gluP: glucose/galactose transporter WARNING 98 427 7.9E-66 T 11-11-2016 IPR005964 Bacterial glucose/galactose transporter GO:0005354|GO:0005355|GO:0009276|GO:0015757|GO:0015758|GO:0016021 AUP74_RS08050 8c1898a4a5042f7a7de366f66b8a6a67 539 Pfam PF03572 Peptidase family S41 268 417 1.1E-12 T 11-11-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 AUP74_RS08050 8c1898a4a5042f7a7de366f66b8a6a67 539 SUPERFAMILY SSF52096 261 348 1.36E-26 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS08050 8c1898a4a5042f7a7de366f66b8a6a67 539 SUPERFAMILY SSF52096 376 454 1.36E-26 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS08050 8c1898a4a5042f7a7de366f66b8a6a67 539 SUPERFAMILY SSF52096 136 177 1.36E-26 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS08050 8c1898a4a5042f7a7de366f66b8a6a67 539 Gene3D G3DSA:3.90.226.10 234 445 3.1E-25 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS11980 8819221d0453010bc056759b7035cb11 388 Gene3D G3DSA:3.40.47.10 206 225 3.5E-21 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS11980 8819221d0453010bc056759b7035cb11 388 Gene3D G3DSA:3.40.47.10 4 107 3.5E-21 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS11980 8819221d0453010bc056759b7035cb11 388 Pfam PF02803 Thiolase, C-terminal domain 266 353 1.9E-9 T 11-11-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 AUP74_RS11980 8819221d0453010bc056759b7035cb11 388 PIRSF PIRSF000429 2 386 2.3E-47 T 11-11-2016 IPR002155 Thiolase GO:0008152|GO:0016747 AUP74_RS11980 8819221d0453010bc056759b7035cb11 388 SUPERFAMILY SSF53901 5 105 2.04E-37 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS11980 8819221d0453010bc056759b7035cb11 388 SUPERFAMILY SSF53901 187 356 2.04E-37 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS11980 8819221d0453010bc056759b7035cb11 388 Pfam PF00108 Thiolase, N-terminal domain 6 172 8.4E-13 T 11-11-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 AUP74_RS11980 8819221d0453010bc056759b7035cb11 388 Gene3D G3DSA:3.40.47.10 244 379 6.3E-20 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 AUP74_RS12520 0b5b30df66df623ffd096132ebd789b1 168 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 13 112 1.4E-19 T 11-11-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 AUP74_RS12520 0b5b30df66df623ffd096132ebd789b1 168 Gene3D G3DSA:3.40.140.10 6 153 9.8E-40 T 11-11-2016 AUP74_RS12520 0b5b30df66df623ffd096132ebd789b1 168 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 64 101 - T 11-11-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 AUP74_RS12520 0b5b30df66df623ffd096132ebd789b1 168 SUPERFAMILY SSF53927 9 150 7.53E-37 T 11-11-2016 IPR016193 Cytidine deaminase-like GO:0003824 AUP74_RS09670 4c00cf414db5219ed0bea7d3420280e3 130 SUPERFAMILY SSF48619 21 74 5.47E-7 T 11-11-2016 IPR016090 Phospholipase A2 domain KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 AUP74_RS09670 4c00cf414db5219ed0bea7d3420280e3 130 Gene3D G3DSA:1.20.90.10 22 67 4.0E-4 T 11-11-2016 IPR016090 Phospholipase A2 domain KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 AUP74_RS16880 0b5a9261d4f8fb3c9f122328daa3fb6c 152 Pfam PF06295 Protein of unknown function (DUF1043) 13 127 1.8E-15 T 11-11-2016 IPR009386 Protein of unknown function DUF1043 AUP74_RS09875 1cae93700f3222b7e5349fe3c25467f9 616 Pfam PF05960 Bacterial protein of unknown function (DUF885) 76 609 8.0E-103 T 11-11-2016 IPR010281 Protein of unknown function DUF885 AUP74_RS09830 a3ca6f757ce06562deb73255341eb8ba 241 Gene3D G3DSA:3.40.50.300 4 171 5.6E-43 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS09830 a3ca6f757ce06562deb73255341eb8ba 241 Gene3D G3DSA:1.10.8.60 175 240 3.2E-27 T 11-11-2016 AUP74_RS09830 a3ca6f757ce06562deb73255341eb8ba 241 TIGRFAM TIGR03420 DnaA_homol_Hda: DnaA regulatory inactivator Hda 10 239 8.1E-85 T 11-11-2016 IPR017788 DnaA regulatory inactivator Hda GO:0032297 AUP74_RS09830 a3ca6f757ce06562deb73255341eb8ba 241 SUPERFAMILY SSF52540 17 220 1.18E-27 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS09830 a3ca6f757ce06562deb73255341eb8ba 241 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 51 71 1.0E-5 T 11-11-2016 IPR020591 Chromosomal replication control, initiator DnaA-like AUP74_RS09830 a3ca6f757ce06562deb73255341eb8ba 241 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 139 166 1.0E-5 T 11-11-2016 IPR020591 Chromosomal replication control, initiator DnaA-like AUP74_RS09830 a3ca6f757ce06562deb73255341eb8ba 241 Pfam PF00308 Bacterial dnaA protein 18 219 1.9E-22 T 11-11-2016 IPR013317 Chromosomal replication initiator protein DnaA AUP74_RS07930 e71377910ab9397a595a4f6e620190e2 197 Gene3D G3DSA:3.40.1130.10 7 144 8.4E-4 T 11-11-2016 AUP74_RS07930 e71377910ab9397a595a4f6e620190e2 197 SMART SM00563 43 152 2.4E-13 T 11-11-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 AUP74_RS07930 e71377910ab9397a595a4f6e620190e2 197 SUPERFAMILY SSF69593 17 153 9.94E-15 T 11-11-2016 AUP74_RS06630 c259258b593293f773474bc51000ca40 136 Pfam PF04519 Polymer-forming cytoskeletal 10 110 1.7E-27 T 11-11-2016 IPR007607 Protein of unknown function DUF583 AUP74_RS09715 6638995f492dd55b09149ff0bcd20861 538 SUPERFAMILY SSF161098 287 537 4.19E-38 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AUP74_RS09715 6638995f492dd55b09149ff0bcd20861 538 Gene3D G3DSA:1.10.3720.10 296 537 5.1E-28 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AUP74_RS09715 6638995f492dd55b09149ff0bcd20861 538 Gene3D G3DSA:1.10.3720.10 13 268 1.3E-39 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AUP74_RS09715 6638995f492dd55b09149ff0bcd20861 538 SUPERFAMILY SSF161098 10 261 1.83E-47 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AUP74_RS09715 6638995f492dd55b09149ff0bcd20861 538 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 345 533 2.3E-8 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AUP74_RS09715 6638995f492dd55b09149ff0bcd20861 538 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 68 267 2.4E-14 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 AUP74_RS01085 fa1732bd61e8683f675e04f6a5cc64f5 139 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 5 129 7.3E-32 T 11-11-2016 IPR007182 Na+/H+ antiporter MnhB subunit-related protein AUP74_RS00685 5767cb09a59fb62505835c81abff3fe0 537 Gene3D G3DSA:3.40.50.300 289 511 6.5E-20 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS00685 5767cb09a59fb62505835c81abff3fe0 537 SUPERFAMILY SSF52540 288 511 6.38E-38 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS00685 5767cb09a59fb62505835c81abff3fe0 537 Gene3D G3DSA:1.25.40.10 25 250 4.1E-19 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS00685 5767cb09a59fb62505835c81abff3fe0 537 Pfam PF13469 Sulfotransferase family 290 476 1.5E-32 T 11-11-2016 AUP74_RS00685 5767cb09a59fb62505835c81abff3fe0 537 SUPERFAMILY SSF48452 41 247 2.97E-17 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS00685 5767cb09a59fb62505835c81abff3fe0 537 SMART SM00028 146 179 36.0 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS00685 5767cb09a59fb62505835c81abff3fe0 537 SMART SM00028 44 77 0.84 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS03805 50d373a586861f8842b30c38a673311c 541 SMART SM00098 75 539 4.4E-157 T 11-11-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 AUP74_RS03805 50d373a586861f8842b30c38a673311c 541 Gene3D G3DSA:3.40.720.10 51 537 2.2E-164 T 11-11-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 AUP74_RS03805 50d373a586861f8842b30c38a673311c 541 SUPERFAMILY SSF53649 66 537 2.84E-146 T 11-11-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 AUP74_RS03805 50d373a586861f8842b30c38a673311c 541 Pfam PF00245 Alkaline phosphatase 74 534 5.3E-124 T 11-11-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 AUP74_RS03805 50d373a586861f8842b30c38a673311c 541 PRINTS PR00113 Alkaline phosphatase signature 177 197 4.5E-48 T 11-11-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 AUP74_RS03805 50d373a586861f8842b30c38a673311c 541 PRINTS PR00113 Alkaline phosphatase signature 331 360 4.5E-48 T 11-11-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 AUP74_RS03805 50d373a586861f8842b30c38a673311c 541 PRINTS PR00113 Alkaline phosphatase signature 239 249 4.5E-48 T 11-11-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 AUP74_RS03805 50d373a586861f8842b30c38a673311c 541 PRINTS PR00113 Alkaline phosphatase signature 74 94 4.5E-48 T 11-11-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 AUP74_RS03805 50d373a586861f8842b30c38a673311c 541 PRINTS PR00113 Alkaline phosphatase signature 130 145 4.5E-48 T 11-11-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 AUP74_RS03145 423efb74667ecb185f76cf45d6ca8bee 405 SUPERFAMILY SSF103473 5 395 3.92E-36 T 11-11-2016 IPR020846 Major facilitator superfamily domain AUP74_RS03145 423efb74667ecb185f76cf45d6ca8bee 405 Gene3D G3DSA:1.20.1250.20 210 396 1.3E-8 T 11-11-2016 AUP74_RS03145 423efb74667ecb185f76cf45d6ca8bee 405 Gene3D G3DSA:1.20.1250.20 8 182 4.3E-16 T 11-11-2016 AUP74_RS03145 423efb74667ecb185f76cf45d6ca8bee 405 Pfam PF07690 Major Facilitator Superfamily 11 341 5.8E-18 T 11-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AUP74_RS15810 9f6a82f26ff48b429b245fa541917977 446 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 16 360 1.0E-134 T 11-11-2016 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 AUP74_RS15810 9f6a82f26ff48b429b245fa541917977 446 Pfam PF13742 OB-fold nucleic acid binding domain 15 108 7.7E-31 T 11-11-2016 IPR025824 OB-fold nucleic acid binding domain GO:0003676 AUP74_RS15810 9f6a82f26ff48b429b245fa541917977 446 Pfam PF02601 Exonuclease VII, large subunit 131 443 9.0E-102 T 11-11-2016 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 AUP74_RS15810 9f6a82f26ff48b429b245fa541917977 446 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 12 446 29.918 T 11-11-2016 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 AUP74_RS09330 4f2e565a3d4a1b5903dff2d8deb80135 381 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 2 354 1.2E-109 T 11-11-2016 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 AUP74_RS09330 4f2e565a3d4a1b5903dff2d8deb80135 381 Pfam PF03739 Predicted permease YjgP/YjgQ family 5 354 1.3E-69 T 11-11-2016 IPR005495 Permease LptG/LptF-related GO:0016021 AUP74_RS09570 838b94d66277b120643eb875d5822060 374 SUPERFAMILY SSF53335 110 362 5.84E-75 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS09570 838b94d66277b120643eb875d5822060 374 PIRSF PIRSF003085 5 372 9.8E-118 T 11-11-2016 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 AUP74_RS09570 838b94d66277b120643eb875d5822060 374 Pfam PF02353 Mycolic acid cyclopropane synthetase 100 360 5.0E-93 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS09570 838b94d66277b120643eb875d5822060 374 Gene3D G3DSA:3.40.50.150 99 362 2.2E-92 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS11225 a74f80f30c27d1633c48502a59a59999 624 SUPERFAMILY SSF54534 224 359 2.75E-25 T 11-11-2016 AUP74_RS11225 a74f80f30c27d1633c48502a59a59999 624 Pfam PF13616 PPIC-type PPIASE domain 268 359 1.5E-18 T 11-11-2016 AUP74_RS11225 a74f80f30c27d1633c48502a59a59999 624 Pfam PF13624 SurA N-terminal domain 1 164 8.9E-40 T 11-11-2016 AUP74_RS11225 a74f80f30c27d1633c48502a59a59999 624 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 298 319 - T 11-11-2016 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-936440 AUP74_RS11225 a74f80f30c27d1633c48502a59a59999 624 Gene3D G3DSA:3.10.50.40 264 382 4.4E-33 T 11-11-2016 AUP74_RS11225 a74f80f30c27d1633c48502a59a59999 624 SUPERFAMILY SSF109998 43 168 2.55E-30 T 11-11-2016 IPR027304 Trigger factor/SurA domain AUP74_RS11225 a74f80f30c27d1633c48502a59a59999 624 SUPERFAMILY SSF109998 202 240 2.55E-30 T 11-11-2016 IPR027304 Trigger factor/SurA domain AUP74_RS11375 717cc8639caf25f616aef038737ec21f 202 Pfam PF02517 CAAX protease self-immunity 92 178 3.8E-15 T 11-11-2016 IPR003675 CAAX amino terminal protease GO:0016020 AUP74_RS04725 7c3496fa7439892c1a113fb5f4d06084 297 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 67 89 - T 11-11-2016 IPR030470 UbiA prenyltransferase conserved site AUP74_RS04725 7c3496fa7439892c1a113fb5f4d06084 297 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 14 292 2.7E-104 T 11-11-2016 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 AUP74_RS04725 7c3496fa7439892c1a113fb5f4d06084 297 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 12 293 20.272 T 11-11-2016 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 AUP74_RS04725 7c3496fa7439892c1a113fb5f4d06084 297 Pfam PF01040 UbiA prenyltransferase family 30 274 2.5E-63 T 11-11-2016 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 AUP74_RS15475 b7e2181c344135e5c6d955362c6df4f4 249 Pfam PF04536 Acid phosphatase of thylakoid lumen protein 35 157 1.8E-41 T 11-11-2016 IPR007621 TPM domain AUP74_RS03965 a2fe26db7047118a243520b3ccad1cf7 134 Pfam PF07681 DoxX 6 72 8.8E-6 T 11-11-2016 IPR032808 DoxX family AUP74_RS14670 cffca7b9eb0478cccaa33a475546394b 326 Gene3D G3DSA:3.40.50.1820 25 285 2.2E-19 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS14670 cffca7b9eb0478cccaa33a475546394b 326 SUPERFAMILY SSF53474 24 264 7.44E-17 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS00405 00fb3e36d9df989a60bd29c1d74967a9 149 Pfam PF07295 Zinc-ribbon containing domain 11 141 4.7E-18 T 11-11-2016 IPR009912 Zinc-ribbon containing domain AUP74_RS15245 ff8b7fc14d1e5d433fc2a04a47cf2cb1 164 SUPERFAMILY SSF55729 1 151 5.59E-34 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS15245 ff8b7fc14d1e5d433fc2a04a47cf2cb1 164 Pfam PF13673 Acetyltransferase (GNAT) domain 78 149 2.8E-15 T 11-11-2016 IPR000182 GNAT domain GO:0008080 AUP74_RS15245 ff8b7fc14d1e5d433fc2a04a47cf2cb1 164 Gene3D G3DSA:3.40.630.30 3 150 1.0E-43 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS02940 3e28aedb2027d29391f9f892d7ef7cd5 274 Pfam PF01841 Transglutaminase-like superfamily 139 209 2.9E-7 T 11-11-2016 IPR002931 Transglutaminase-like AUP74_RS02940 3e28aedb2027d29391f9f892d7ef7cd5 274 SUPERFAMILY SSF54001 142 220 4.12E-10 T 11-11-2016 AUP74_RS07495 a7c20aa5bb60d857c15dee86eba371f5 388 SUPERFAMILY SSF54626 39 171 2.22E-5 T 11-11-2016 IPR016087 Chalcone isomerase GO:0016872 AUP74_RS07495 a7c20aa5bb60d857c15dee86eba371f5 388 Pfam PF16036 Chalcone isomerase-like 15 170 9.0E-19 T 11-11-2016 IPR016087 Chalcone isomerase GO:0016872 AUP74_RS07495 a7c20aa5bb60d857c15dee86eba371f5 388 SUPERFAMILY SSF74653 270 387 1.19E-17 T 11-11-2016 AUP74_RS07495 a7c20aa5bb60d857c15dee86eba371f5 388 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 310 386 2.9E-18 T 11-11-2016 IPR006260 TonB, C-terminal GO:0006810 AUP74_RS07495 a7c20aa5bb60d857c15dee86eba371f5 388 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 310 386 4.4E-17 T 11-11-2016 IPR006260 TonB, C-terminal GO:0006810 AUP74_RS07495 a7c20aa5bb60d857c15dee86eba371f5 388 Gene3D G3DSA:3.30.1150.10 274 387 8.0E-16 T 11-11-2016 AUP74_RS09880 cecf6fbf3885f5fa48b62bbbb600aa0a 113 SUPERFAMILY SSF55248 16 111 2.62E-35 T 11-11-2016 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 AUP74_RS09880 cecf6fbf3885f5fa48b62bbbb600aa0a 113 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 16 111 23.422 T 11-11-2016 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 AUP74_RS09880 cecf6fbf3885f5fa48b62bbbb600aa0a 113 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 19 109 2.1E-32 T 11-11-2016 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 AUP74_RS09880 cecf6fbf3885f5fa48b62bbbb600aa0a 113 Gene3D G3DSA:3.30.1360.20 12 111 8.3E-34 T 11-11-2016 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 AUP74_RS05875 21ebf3de7e97cf82418d1732a779f5a4 325 Pfam PF12224 Putative amidoligase enzyme 20 278 1.1E-63 T 11-11-2016 IPR022025 Putative amidoligase enzyme AUP74_RS05460 b8909197076c334c81788f015f030399 86 Pfam PF13627 Prokaryotic lipoprotein-attachment site 9 30 9.9E-9 T 11-11-2016 IPR032831 Prokaryotic lipoprotein-attachment site AUP74_RS04795 d639350b343140dde9f13e0458d8ee90 219 SUPERFAMILY SSF53271 3 210 1.28E-48 T 11-11-2016 IPR029057 Phosphoribosyltransferase-like AUP74_RS04795 d639350b343140dde9f13e0458d8ee90 219 Pfam PF00156 Phosphoribosyl transferase domain 10 194 1.7E-25 T 11-11-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 AUP74_RS04795 d639350b343140dde9f13e0458d8ee90 219 Gene3D G3DSA:3.40.50.2020 98 203 4.5E-40 T 11-11-2016 IPR029057 Phosphoribosyltransferase-like AUP74_RS04795 d639350b343140dde9f13e0458d8ee90 219 Gene3D G3DSA:3.40.50.2020 3 63 4.5E-40 T 11-11-2016 IPR029057 Phosphoribosyltransferase-like AUP74_RS12975 5f530b30e964b1afbbf8020c77e31b86 435 SUPERFAMILY SSF51905 353 413 2.4E-44 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS12975 5f530b30e964b1afbbf8020c77e31b86 435 SUPERFAMILY SSF51905 37 261 2.4E-44 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS12975 5f530b30e964b1afbbf8020c77e31b86 435 Gene3D G3DSA:3.50.50.60 23 127 1.9E-54 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS12975 5f530b30e964b1afbbf8020c77e31b86 435 Gene3D G3DSA:3.50.50.60 353 400 1.9E-54 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS12975 5f530b30e964b1afbbf8020c77e31b86 435 Gene3D G3DSA:3.50.50.60 181 260 1.9E-54 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AUP74_RS12975 5f530b30e964b1afbbf8020c77e31b86 435 Pfam PF01266 FAD dependent oxidoreductase 38 389 1.1E-57 T 11-11-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AUP74_RS04930 8bcb71f1b43e9b7777fc4a5c3d6fb0a0 443 Pfam PF01523 Putative modulator of DNA gyrase 29 312 3.4E-35 T 11-11-2016 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 AUP74_RS04930 8bcb71f1b43e9b7777fc4a5c3d6fb0a0 443 SUPERFAMILY SSF111283 9 436 7.32E-78 T 11-11-2016 AUP74_RS03040 098093957fe4f6f25cacfc5477ae046e 308 Pfam PF07582 AP endonuclease family 2 C terminus 257 299 8.5E-5 T 11-11-2016 IPR011418 AP endonuclease, family 2, C-terminal AUP74_RS03040 098093957fe4f6f25cacfc5477ae046e 308 SUPERFAMILY SSF51658 34 301 1.38E-40 T 11-11-2016 IPR013022 Xylose isomerase-like, TIM barrel domain AUP74_RS03040 098093957fe4f6f25cacfc5477ae046e 308 Gene3D G3DSA:3.20.20.150 37 294 1.8E-33 T 11-11-2016 IPR013022 Xylose isomerase-like, TIM barrel domain AUP74_RS03040 098093957fe4f6f25cacfc5477ae046e 308 Pfam PF01261 Xylose isomerase-like TIM barrel 72 223 3.2E-14 T 11-11-2016 IPR013022 Xylose isomerase-like, TIM barrel domain AUP74_RS11040 6e06612bca1d51afb7357748b10e66a1 272 Pfam PF11927 Protein of unknown function (DUF3445) 2 226 1.0E-49 T 11-11-2016 IPR021848 Protein of unknown function DUF3445 AUP74_RS07900 244e3fd3f29b2a181f6194ef48af7f0a 187 Pfam PF01464 Transglycosylase SLT domain 84 172 4.3E-19 T 11-11-2016 IPR008258 Transglycosylase SLT domain 1 AUP74_RS07900 244e3fd3f29b2a181f6194ef48af7f0a 187 Gene3D G3DSA:1.10.530.10 75 172 1.1E-26 T 11-11-2016 AUP74_RS07900 244e3fd3f29b2a181f6194ef48af7f0a 187 SUPERFAMILY SSF53955 73 182 4.15E-30 T 11-11-2016 IPR023346 Lysozyme-like domain AUP74_RS11090 8dec42e16bce8d891ce7b42a013e9030 266 Gene3D G3DSA:3.40.50.720 2 263 8.9E-45 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS11090 8dec42e16bce8d891ce7b42a013e9030 266 Pfam PF00899 ThiF family 18 165 7.0E-33 T 11-11-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 AUP74_RS11090 8dec42e16bce8d891ce7b42a013e9030 266 SUPERFAMILY SSF69572 2 264 3.27E-57 T 11-11-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 AUP74_RS04855 883854af7e4cf34fd62daa9300d3d205 448 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 35 444 5.7E-86 T 11-11-2016 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 AUP74_RS04855 883854af7e4cf34fd62daa9300d3d205 448 Pfam PF00939 Sodium:sulfate symporter transmembrane region 10 443 9.9E-42 T 11-11-2016 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 AUP74_RS02930 2296a71d830a832596fd15bd5023d28c 797 Pfam PF17148 Domain of unknown function (DUF5117) 82 272 3.0E-38 T 11-11-2016 IPR033413 Domain of unknown function DUF5117 AUP74_RS02930 2296a71d830a832596fd15bd5023d28c 797 SUPERFAMILY SSF55486 213 470 1.19E-25 T 11-11-2016 AUP74_RS02930 2296a71d830a832596fd15bd5023d28c 797 Gene3D G3DSA:3.40.390.10 387 471 3.9E-8 T 11-11-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 AUP74_RS02930 2296a71d830a832596fd15bd5023d28c 797 Pfam PF16313 Met-zincin 396 698 2.5E-67 T 11-11-2016 IPR032534 Domian of unknown function DUF4953 AUP74_RS13265 0b3a690bdeed77bdc79f7edf78c0849f 76 Pfam PF11174 Protein of unknown function (DUF2970) 17 72 1.8E-21 T 11-11-2016 IPR021344 Protein of unknown function DUF2970 AUP74_RS01130 519774688d22d7b8610c487c16e28035 415 Pfam PF11700 Vacuole effluxer Atg22 like 56 129 1.0E-8 T 11-11-2016 IPR024671 Autophagy-related protein 22-like AUP74_RS01130 519774688d22d7b8610c487c16e28035 415 Pfam PF11700 Vacuole effluxer Atg22 like 137 408 3.3E-44 T 11-11-2016 IPR024671 Autophagy-related protein 22-like AUP74_RS01130 519774688d22d7b8610c487c16e28035 415 SUPERFAMILY SSF103473 4 411 1.19E-38 T 11-11-2016 IPR020846 Major facilitator superfamily domain AUP74_RS01130 519774688d22d7b8610c487c16e28035 415 Gene3D G3DSA:1.20.1250.20 19 196 1.3E-9 T 11-11-2016 AUP74_RS01130 519774688d22d7b8610c487c16e28035 415 Gene3D G3DSA:1.20.1250.20 232 412 3.8E-19 T 11-11-2016 AUP74_RS00900 0e5c7b5a9aab3e5e46182c5a9f062541 270 Pfam PF13432 Tetratricopeptide repeat 161 221 2.3E-11 T 11-11-2016 AUP74_RS00900 0e5c7b5a9aab3e5e46182c5a9f062541 270 SUPERFAMILY SSF48452 155 257 2.28E-12 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS00900 0e5c7b5a9aab3e5e46182c5a9f062541 270 Pfam PF16331 TolA binding protein trimerisation 57 115 1.6E-11 T 11-11-2016 IPR032519 YbgF, trimerisation domain GO:0070206 AUP74_RS00900 0e5c7b5a9aab3e5e46182c5a9f062541 270 Pfam PF13174 Tetratricopeptide repeat 227 251 0.01 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS00900 0e5c7b5a9aab3e5e46182c5a9f062541 270 Gene3D G3DSA:1.25.40.10 162 254 4.5E-12 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS14505 4d3e1c1648699fe07e55557652c56468 271 PIRSF PIRSF015736 10 271 6.2E-51 T 11-11-2016 IPR026286 Maleate isomerase/Arylmalonate decarboxylase AUP74_RS15330 fbcab48e4686066cf5bfd4c2f8c99c8f 271 TIGRFAM TIGR00444 mazG: MazG family protein 13 266 3.8E-95 T 11-11-2016 IPR011551 NTP pyrophosphohydrolase MazG AUP74_RS15330 fbcab48e4686066cf5bfd4c2f8c99c8f 271 SUPERFAMILY SSF101386 6 105 3.93E-22 T 11-11-2016 AUP74_RS15330 fbcab48e4686066cf5bfd4c2f8c99c8f 271 Gene3D G3DSA:1.10.287.1080 145 229 2.7E-14 T 11-11-2016 AUP74_RS15330 fbcab48e4686066cf5bfd4c2f8c99c8f 271 Gene3D G3DSA:1.10.287.1080 24 74 2.0E-8 T 11-11-2016 AUP74_RS15330 fbcab48e4686066cf5bfd4c2f8c99c8f 271 SUPERFAMILY SSF101386 148 244 2.8E-25 T 11-11-2016 AUP74_RS15330 fbcab48e4686066cf5bfd4c2f8c99c8f 271 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 30 103 6.4E-26 T 11-11-2016 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core AUP74_RS15330 fbcab48e4686066cf5bfd4c2f8c99c8f 271 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 176 237 9.0E-10 T 11-11-2016 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core AUP74_RS01505 5a7ea5dbd577f5b5af65c49175b80924 154 Gene3D G3DSA:3.40.30.10 6 154 1.2E-33 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS01505 5a7ea5dbd577f5b5af65c49175b80924 154 Pfam PF00578 AhpC/TSA family 6 133 3.6E-5 T 11-11-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AUP74_RS01505 5a7ea5dbd577f5b5af65c49175b80924 154 SUPERFAMILY SSF52833 6 152 4.11E-19 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS06190 0cb5d02e94e97ce44ab5e4e60bc889a2 60 Pfam PF11293 Protein of unknown function (DUF3094) 5 55 3.7E-16 T 11-11-2016 IPR021444 Protein of unknown function DUF3094 AUP74_RS16340 588d223425ab3ecff7ac326d89d70f21 462 Pfam PF00120 Glutamine synthetase, catalytic domain 122 457 1.6E-99 T 11-11-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AUP74_RS16340 588d223425ab3ecff7ac326d89d70f21 462 Gene3D G3DSA:3.30.590.10 123 448 2.6E-86 T 11-11-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 AUP74_RS16340 588d223425ab3ecff7ac326d89d70f21 462 SUPERFAMILY SSF54368 19 118 2.35E-18 T 11-11-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AUP74_RS16340 588d223425ab3ecff7ac326d89d70f21 462 Gene3D G3DSA:3.10.20.70 24 122 1.5E-16 T 11-11-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AUP74_RS16340 588d223425ab3ecff7ac326d89d70f21 462 SUPERFAMILY SSF55931 122 458 2.35E-98 T 11-11-2016 AUP74_RS16340 588d223425ab3ecff7ac326d89d70f21 462 SMART SM01230 120 378 1.9E-97 T 11-11-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AUP74_RS16340 588d223425ab3ecff7ac326d89d70f21 462 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 256 271 - T 11-11-2016 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 AUP74_RS03685 de04bce24e141f98b66c9e3c51e6467f 703 SUPERFAMILY SSF53474 438 687 8.49E-49 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS03685 de04bce24e141f98b66c9e3c51e6467f 703 Pfam PF00326 Prolyl oligopeptidase family 485 700 6.6E-59 T 11-11-2016 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 AUP74_RS03685 de04bce24e141f98b66c9e3c51e6467f 703 SUPERFAMILY SSF50993 22 434 1.65E-88 T 11-11-2016 AUP74_RS03685 de04bce24e141f98b66c9e3c51e6467f 703 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 469 487 1.6E-51 T 11-11-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 AUP74_RS03685 de04bce24e141f98b66c9e3c51e6467f 703 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 628 650 1.6E-51 T 11-11-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 AUP74_RS03685 de04bce24e141f98b66c9e3c51e6467f 703 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 609 624 1.6E-51 T 11-11-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 AUP74_RS03685 de04bce24e141f98b66c9e3c51e6467f 703 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 495 519 1.6E-51 T 11-11-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 AUP74_RS03685 de04bce24e141f98b66c9e3c51e6467f 703 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 553 573 1.6E-51 T 11-11-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 AUP74_RS03685 de04bce24e141f98b66c9e3c51e6467f 703 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 523 542 1.6E-51 T 11-11-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 AUP74_RS03685 de04bce24e141f98b66c9e3c51e6467f 703 Gene3D G3DSA:3.40.50.1820 437 688 8.3E-48 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS03685 de04bce24e141f98b66c9e3c51e6467f 703 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 25 427 1.4E-114 T 11-11-2016 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 AUP74_RS03685 de04bce24e141f98b66c9e3c51e6467f 703 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 530 560 - T 11-11-2016 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 AUP74_RS03685 de04bce24e141f98b66c9e3c51e6467f 703 Gene3D G3DSA:2.130.10.120 92 428 4.0E-101 T 11-11-2016 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 AUP74_RS12580 615975bf1def787aa6eea6feebf38d40 208 Gene3D G3DSA:3.40.50.850 1 204 2.2E-48 T 11-11-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 AUP74_RS12580 615975bf1def787aa6eea6feebf38d40 208 Pfam PF00857 Isochorismatase family 14 165 3.3E-22 T 11-11-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 AUP74_RS12580 615975bf1def787aa6eea6feebf38d40 208 SUPERFAMILY SSF52499 3 203 1.23E-52 T 11-11-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 AUP74_RS06555 8ae81b82ccc02c7fc20a6e2553da1463 338 Gene3D G3DSA:3.40.1190.20 1 322 1.8E-65 T 11-11-2016 IPR029056 Ribokinase-like AUP74_RS06555 8ae81b82ccc02c7fc20a6e2553da1463 338 Pfam PF00294 pfkB family carbohydrate kinase 56 318 7.3E-53 T 11-11-2016 IPR011611 Carbohydrate kinase PfkB AUP74_RS06555 8ae81b82ccc02c7fc20a6e2553da1463 338 PRINTS PR00990 Ribokinase signature 246 257 6.8E-6 T 11-11-2016 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 AUP74_RS06555 8ae81b82ccc02c7fc20a6e2553da1463 338 PRINTS PR00990 Ribokinase signature 208 223 6.8E-6 T 11-11-2016 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 AUP74_RS06555 8ae81b82ccc02c7fc20a6e2553da1463 338 PRINTS PR00990 Ribokinase signature 57 76 6.8E-6 T 11-11-2016 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 AUP74_RS06555 8ae81b82ccc02c7fc20a6e2553da1463 338 SUPERFAMILY SSF53613 1 318 2.18E-73 T 11-11-2016 IPR029056 Ribokinase-like AUP74_RS06555 8ae81b82ccc02c7fc20a6e2553da1463 338 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 275 288 - T 11-11-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 AUP74_RS05445 9b47442a4f279852e9d5679ad9cb5814 220 Pfam PF04340 Protein of unknown function, DUF484 2 215 1.5E-57 T 11-11-2016 IPR007435 Protein of unknown function DUF484 AUP74_RS16095 b44020ccbfa92aa84fd85d0ac0dfb200 985 TIGRFAM TIGR03504 FimV_Cterm: FimV C-terminal domain 941 983 2.8E-18 T 11-11-2016 IPR020011 Motility protein FimV, C-terminal AUP74_RS16095 b44020ccbfa92aa84fd85d0ac0dfb200 985 Gene3D G3DSA:1.25.40.10 935 967 5.9E-8 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS16095 b44020ccbfa92aa84fd85d0ac0dfb200 985 Gene3D G3DSA:1.25.40.10 570 626 5.9E-8 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS16095 b44020ccbfa92aa84fd85d0ac0dfb200 985 TIGRFAM TIGR03505 FimV_core: FimV N-terminal domain 225 298 1.0E-26 T 11-11-2016 IPR020012 Motility protein FimV, N-terminal AUP74_RS00610 b045715951a8790cba1786f5eda86fa3 95 SUPERFAMILY SSF160191 2 87 1.31E-34 T 11-11-2016 AUP74_RS00610 b045715951a8790cba1786f5eda86fa3 95 Pfam PF05166 YcgL domain 5 77 1.9E-31 T 11-11-2016 IPR027354 YcgL domain AUP74_RS00610 b045715951a8790cba1786f5eda86fa3 95 Hamap MF_01866 Protein YcgL [ycgL]. 3 90 25.554 T 11-11-2016 IPR027354 YcgL domain AUP74_RS00610 b045715951a8790cba1786f5eda86fa3 95 ProDom PD030374 YCGL UNCHARACTERIZED SIMILAR BACTERIA HI1446 Y2231 HYDROLASE CYTOPLASMIC YPO2080 SO2575 4 78 8.0E-23 T 11-11-2016 IPR027354 YcgL domain AUP74_RS08560 3a1a133f7ec9ad7144de7185889ef4c0 97 Pfam PF07561 Domain of Unknown Function (DUF1540) 12 44 1.5E-5 T 11-11-2016 IPR011437 Domain of unknown function DUF1540 AUP74_RS08560 3a1a133f7ec9ad7144de7185889ef4c0 97 Pfam PF07561 Domain of Unknown Function (DUF1540) 62 94 0.0064 T 11-11-2016 IPR011437 Domain of unknown function DUF1540 AUP74_RS07955 da50672eff3ffe1c2a515c51c0903579 291 SUPERFAMILY SSF53474 44 290 1.0E-35 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS07955 da50672eff3ffe1c2a515c51c0903579 291 Pfam PF12146 Serine aminopeptidase, S33 84 193 1.4E-19 T 11-11-2016 IPR022742 Serine aminopeptidase, S33 AUP74_RS07955 da50672eff3ffe1c2a515c51c0903579 291 Gene3D G3DSA:3.40.50.1820 67 290 1.1E-33 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS06960 8f2019c38b263a47c265f0428c8f962e 81 Pfam PF07023 Protein of unknown function (DUF1315) 4 75 1.6E-24 T 11-11-2016 IPR009749 Protein of unknown function DUF1315 AUP74_RS16265 8ab0413d38a8c58eaaeeb8cf5fbd6c51 417 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 50 346 3.4E-8 T 11-11-2016 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 AUP74_RS16265 8ab0413d38a8c58eaaeeb8cf5fbd6c51 417 Gene3D G3DSA:3.20.20.80 15 416 6.1E-109 T 11-11-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 AUP74_RS16265 8ab0413d38a8c58eaaeeb8cf5fbd6c51 417 SUPERFAMILY SSF51445 15 381 3.17E-52 T 11-11-2016 IPR017853 Glycoside hydrolase superfamily AUP74_RS02495 cbb619b57d8e700dad21350993669eec 103 Pfam PF09904 Winged helix-turn helix 10 98 1.9E-29 T 11-11-2016 IPR017162 Uncharacterised conserved protein UCP037266 AUP74_RS02495 cbb619b57d8e700dad21350993669eec 103 PIRSF PIRSF037266 4 101 4.9E-31 T 11-11-2016 IPR017162 Uncharacterised conserved protein UCP037266 AUP74_RS14355 b7c27351a0a043a8b1d0aa5ca1eceea5 484 Pfam PF00474 Sodium:solute symporter family 34 410 1.9E-59 T 11-11-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 AUP74_RS03540 8f59095ab24e948b1b59b0e1c2b2d409 361 Pfam PF01594 Domain of unknown function DUF20 11 338 1.9E-54 T 11-11-2016 IPR002549 Transmembrane protein TqsA-like AUP74_RS07655 8f3dac2954a8980eaa8b7668cfaf4bb2 433 SUPERFAMILY SSF48452 89 127 3.5E-5 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS07655 8f3dac2954a8980eaa8b7668cfaf4bb2 433 SUPERFAMILY SSF48452 270 336 3.5E-5 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS07655 8f3dac2954a8980eaa8b7668cfaf4bb2 433 Gene3D G3DSA:1.25.40.10 280 330 1.4E-5 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS07655 8f3dac2954a8980eaa8b7668cfaf4bb2 433 Gene3D G3DSA:1.25.40.10 91 149 1.4E-5 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS07655 8f3dac2954a8980eaa8b7668cfaf4bb2 433 SUPERFAMILY SSF74653 369 428 1.73E-6 T 11-11-2016 AUP74_RS03710 09a402239287718441529f21dad7f511 42 Pfam PF11346 Protein of unknown function (DUF3149) 4 40 3.3E-12 T 11-11-2016 IPR021494 Protein of unknown function DUF3149 AUP74_RS08845 2dc21f7748e12eb016b9cd2d67ce0df8 318 Pfam PF00535 Glycosyl transferase family 2 12 199 1.6E-17 T 11-11-2016 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AUP74_RS08845 2dc21f7748e12eb016b9cd2d67ce0df8 318 SUPERFAMILY SSF53448 7 269 3.22E-44 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases AUP74_RS08845 2dc21f7748e12eb016b9cd2d67ce0df8 318 Gene3D G3DSA:3.90.550.10 8 266 8.2E-36 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases AUP74_RS01585 ef9e9cbfb4c7cc28f9f9689a78b5d018 165 Gene3D G3DSA:2.40.160.20 10 153 6.4E-14 T 11-11-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AUP74_RS01585 ef9e9cbfb4c7cc28f9f9689a78b5d018 165 SUPERFAMILY SSF56925 22 154 2.2E-13 T 11-11-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 AUP74_RS01585 ef9e9cbfb4c7cc28f9f9689a78b5d018 165 Pfam PF13505 Outer membrane protein beta-barrel domain 8 152 5.9E-15 T 11-11-2016 IPR027385 Outer membrane protein beta-barrel AUP74_RS13540 f49d0004102119e9154b58ce441505dd 649 SUPERFAMILY SSF82171 91 365 2.75E-16 T 11-11-2016 AUP74_RS13540 f49d0004102119e9154b58ce441505dd 649 SUPERFAMILY SSF53474 379 631 7.74E-65 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS13540 f49d0004102119e9154b58ce441505dd 649 Gene3D G3DSA:2.130.10.10 93 310 1.0E-15 T 11-11-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 AUP74_RS13540 f49d0004102119e9154b58ce441505dd 649 Pfam PF00326 Prolyl oligopeptidase family 428 631 1.5E-49 T 11-11-2016 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 AUP74_RS13540 f49d0004102119e9154b58ce441505dd 649 Gene3D G3DSA:3.40.50.1820 311 627 6.1E-72 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS08140 1696c738e577b559fb9a0c179745a6c4 456 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 391 453 2.0E-7 T 11-11-2016 IPR006260 TonB, C-terminal GO:0006810 AUP74_RS08140 1696c738e577b559fb9a0c179745a6c4 456 SUPERFAMILY SSF74653 360 452 4.32E-7 T 11-11-2016 AUP74_RS08140 1696c738e577b559fb9a0c179745a6c4 456 Gene3D G3DSA:3.30.1150.10 359 437 3.5E-5 T 11-11-2016 AUP74_RS10105 10f98c6110a44a9b718dde96b2c6c0ab 312 Pfam PF04018 Domain of unknown function (DUF368) 18 251 1.8E-82 T 11-11-2016 IPR007163 Protein of unknown function DUF368 AUP74_RS00500 8e529e12969e91a93f90688d3a81ee33 709 Pfam PF16967 Fimbrial, FimD or usher-like 144 210 2.4E-17 T 11-11-2016 IPR032636 Pilus assembly protein domain AUP74_RS15655 0e4905d7fea1aa9e9d4d7fd45c74ca64 249 PRINTS PR00395 Ribosomal protein S2 signature 37 46 8.6E-37 T 11-11-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS15655 0e4905d7fea1aa9e9d4d7fd45c74ca64 249 PRINTS PR00395 Ribosomal protein S2 signature 6 24 8.6E-37 T 11-11-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS15655 0e4905d7fea1aa9e9d4d7fd45c74ca64 249 PRINTS PR00395 Ribosomal protein S2 signature 87 104 8.6E-37 T 11-11-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS15655 0e4905d7fea1aa9e9d4d7fd45c74ca64 249 PRINTS PR00395 Ribosomal protein S2 signature 175 186 8.6E-37 T 11-11-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS15655 0e4905d7fea1aa9e9d4d7fd45c74ca64 249 PRINTS PR00395 Ribosomal protein S2 signature 158 175 8.6E-37 T 11-11-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS15655 0e4905d7fea1aa9e9d4d7fd45c74ca64 249 PRINTS PR00395 Ribosomal protein S2 signature 196 210 8.6E-37 T 11-11-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS15655 0e4905d7fea1aa9e9d4d7fd45c74ca64 249 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 11-11-2016 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 AUP74_RS15655 0e4905d7fea1aa9e9d4d7fd45c74ca64 249 Pfam PF00318 Ribosomal protein S2 9 224 1.5E-94 T 11-11-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AUP74_RS15655 0e4905d7fea1aa9e9d4d7fd45c74ca64 249 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 4 225 1.7E-104 T 11-11-2016 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 AUP74_RS15655 0e4905d7fea1aa9e9d4d7fd45c74ca64 249 Gene3D G3DSA:1.10.287.610 100 152 8.7E-25 T 11-11-2016 AUP74_RS15655 0e4905d7fea1aa9e9d4d7fd45c74ca64 249 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 225 40.634 T 11-11-2016 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 AUP74_RS15655 0e4905d7fea1aa9e9d4d7fd45c74ca64 249 SUPERFAMILY SSF52313 6 236 3.92E-93 T 11-11-2016 IPR023591 Ribosomal protein S2, flavodoxin-like domain AUP74_RS15655 0e4905d7fea1aa9e9d4d7fd45c74ca64 249 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 11-11-2016 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 AUP74_RS15655 0e4905d7fea1aa9e9d4d7fd45c74ca64 249 Gene3D G3DSA:3.40.50.10490 158 239 9.9E-64 T 11-11-2016 AUP74_RS15655 0e4905d7fea1aa9e9d4d7fd45c74ca64 249 Gene3D G3DSA:3.40.50.10490 23 99 9.9E-64 T 11-11-2016 AUP74_RS11055 23cf9203f667281c3a5a05d3f5154e5c 319 Pfam PF01758 Sodium Bile acid symporter family 24 206 5.6E-31 T 11-11-2016 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 AUP74_RS16335 636b4a69d075ff0fd8b7fe60aa7e8b9b 320 Pfam PF16154 Domain of unknown function (DUF4862) 4 307 3.1E-102 T 11-11-2016 IPR032344 Protein of unknown function DUF4862 AUP74_RS15235 863a6ebc06f340334fe7aff4690e588d 237 Gene3D G3DSA:3.40.50.1820 23 225 1.2E-26 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS15235 863a6ebc06f340334fe7aff4690e588d 237 SUPERFAMILY SSF53474 24 220 1.19E-26 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS07560 48e935e90f2a59cc820356ee65f347cf 76 Pfam PF13453 Transcription factor zinc-finger 2 43 1.1E-21 T 11-11-2016 IPR027392 Transcription factor zinc-finger AUP74_RS13670 92a94a714c047e64235cd4f7740ef5b5 149 Pfam PF02566 OsmC-like protein 40 142 2.5E-18 T 11-11-2016 IPR003718 OsmC/Ohr family AUP74_RS13670 92a94a714c047e64235cd4f7740ef5b5 149 Gene3D G3DSA:3.30.300.20 6 145 2.1E-47 T 11-11-2016 IPR015946 K homology domain-like, alpha/beta AUP74_RS13670 92a94a714c047e64235cd4f7740ef5b5 149 SUPERFAMILY SSF82784 9 144 1.1E-40 T 11-11-2016 IPR003718 OsmC/Ohr family AUP74_RS07330 e60aa350dc7af6999e063532472bf0e0 262 Gene3D G3DSA:3.40.470.10 178 254 6.7E-4 T 11-11-2016 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AUP74_RS12865 7fa251daf5cdf76f4e453e08bf87b037 384 Gene3D G3DSA:2.60.120.650 7 214 1.0E-35 T 11-11-2016 AUP74_RS12865 7fa251daf5cdf76f4e453e08bf87b037 384 SMART SM00558 93 230 0.0037 T 11-11-2016 IPR003347 JmjC domain AUP74_RS12865 7fa251daf5cdf76f4e453e08bf87b037 384 Pfam PF08007 Cupin superfamily protein 14 287 3.4E-85 T 11-11-2016 IPR003347 JmjC domain AUP74_RS12865 7fa251daf5cdf76f4e453e08bf87b037 384 SUPERFAMILY SSF51197 7 291 1.06E-69 T 11-11-2016 AUP74_RS13210 f224c7881895aadaff45c4b6a50954d2 908 Pfam PF12705 PD-(D/E)XK nuclease superfamily 641 879 2.2E-16 T 11-11-2016 AUP74_RS13210 f224c7881895aadaff45c4b6a50954d2 908 TIGRFAM TIGR03623 TIGR03623: probable DNA repair protein 19 888 1.7E-208 T 11-11-2016 IPR019925 DNA repair protein, predicted AUP74_RS13210 f224c7881895aadaff45c4b6a50954d2 908 SUPERFAMILY SSF52540 226 338 8.6E-29 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS13210 f224c7881895aadaff45c4b6a50954d2 908 SUPERFAMILY SSF52540 375 595 8.6E-29 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS00450 bc6b9c23b2e26a3fa92b250fb61b0263 343 PRINTS PR01486 Bacterial phospholipase A1 protein signature 151 167 6.9E-41 T 11-11-2016 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 AUP74_RS00450 bc6b9c23b2e26a3fa92b250fb61b0263 343 PRINTS PR01486 Bacterial phospholipase A1 protein signature 204 218 6.9E-41 T 11-11-2016 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 AUP74_RS00450 bc6b9c23b2e26a3fa92b250fb61b0263 343 PRINTS PR01486 Bacterial phospholipase A1 protein signature 219 237 6.9E-41 T 11-11-2016 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 AUP74_RS00450 bc6b9c23b2e26a3fa92b250fb61b0263 343 PRINTS PR01486 Bacterial phospholipase A1 protein signature 311 331 6.9E-41 T 11-11-2016 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 AUP74_RS00450 bc6b9c23b2e26a3fa92b250fb61b0263 343 PRINTS PR01486 Bacterial phospholipase A1 protein signature 254 272 6.9E-41 T 11-11-2016 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 AUP74_RS00450 bc6b9c23b2e26a3fa92b250fb61b0263 343 PRINTS PR01486 Bacterial phospholipase A1 protein signature 289 306 6.9E-41 T 11-11-2016 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 AUP74_RS00450 bc6b9c23b2e26a3fa92b250fb61b0263 343 PRINTS PR01486 Bacterial phospholipase A1 protein signature 129 146 6.9E-41 T 11-11-2016 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 AUP74_RS00450 bc6b9c23b2e26a3fa92b250fb61b0263 343 PRINTS PR01486 Bacterial phospholipase A1 protein signature 174 193 6.9E-41 T 11-11-2016 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 AUP74_RS00450 bc6b9c23b2e26a3fa92b250fb61b0263 343 Pfam PF02253 Phospholipase A1 83 338 5.9E-97 T 11-11-2016 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 AUP74_RS00450 bc6b9c23b2e26a3fa92b250fb61b0263 343 SUPERFAMILY SSF56931 82 339 6.67E-87 T 11-11-2016 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 AUP74_RS00450 bc6b9c23b2e26a3fa92b250fb61b0263 343 Gene3D G3DSA:2.40.230.10 79 340 2.8E-89 T 11-11-2016 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 AUP74_RS02800 cdf4f77e9343a3fed8a8183cef815961 176 Pfam PF07819 PGAP1-like protein 41 85 1.9E-6 T 11-11-2016 IPR012908 GPI inositol-deacylase PGAP1-like GO:0016788 Reactome: R-HSA-162791 AUP74_RS02800 cdf4f77e9343a3fed8a8183cef815961 176 Gene3D G3DSA:3.40.50.1820 4 141 1.8E-17 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS02800 cdf4f77e9343a3fed8a8183cef815961 176 SUPERFAMILY SSF53474 9 146 1.95E-19 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS13290 87f03ad63c21616c15744971f3be52a3 439 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 290 297 - T 11-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AUP74_RS13290 87f03ad63c21616c15744971f3be52a3 439 SUPERFAMILY SSF56059 119 346 5.39E-27 T 11-11-2016 AUP74_RS13290 87f03ad63c21616c15744971f3be52a3 439 Gene3D G3DSA:3.30.470.20 93 380 1.6E-18 T 11-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 AUP74_RS10385 7a56b18dd23752f891c0de427a18ce6f 259 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 3 28 2.7E-8 T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS10385 7a56b18dd23752f891c0de427a18ce6f 259 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 7 28 8.0E-7 T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS10385 7a56b18dd23752f891c0de427a18ce6f 259 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 7 27 - T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS07880 673a502d18b50ae7975735a7a3a00f2c 652 Pfam PF12228 Protein of unknown function (DUF3604) 70 652 3.5E-225 T 11-11-2016 IPR022028 Protein of unknown function DUF3604 AUP74_RS07680 55dcfa37cf73a4ad5b9fdee2d3bc5327 383 TIGRFAM TIGR03806 chp_HNE_0200: conserved hypothetical protein, HNE_0200 family 37 378 2.1E-121 T 11-11-2016 IPR022269 Conserved hypothetical protein CHP03806, HNE0200 family AUP74_RS05530 e6aeb2c4e6e30e3164066c495a8394c6 150 Pfam PF14467 Domain of unknown function (DUF4426) 32 147 1.4E-36 T 11-11-2016 IPR025218 Domain of unknown function DUF4426 AUP74_RS08115 fbcabf15f1ec1df914876bd9fcb4ce3e 191 SUPERFAMILY SSF48452 42 178 1.9E-24 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS08115 fbcabf15f1ec1df914876bd9fcb4ce3e 191 Pfam PF13432 Tetratricopeptide repeat 80 142 3.0E-8 T 11-11-2016 AUP74_RS08115 fbcabf15f1ec1df914876bd9fcb4ce3e 191 SMART SM00028 75 108 3.2E-4 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS08115 fbcabf15f1ec1df914876bd9fcb4ce3e 191 SMART SM00028 109 142 0.026 T 11-11-2016 IPR019734 Tetratricopeptide repeat GO:0005515 AUP74_RS08115 fbcabf15f1ec1df914876bd9fcb4ce3e 191 Gene3D G3DSA:1.25.40.10 40 178 1.8E-28 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 AUP74_RS06755 7b5131c20365d9fade0b072f55e64004 122 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 69 97 - T 11-11-2016 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AUP74_RS06755 7b5131c20365d9fade0b072f55e64004 122 Gene3D G3DSA:1.20.5.1030 63 121 4.6E-23 T 11-11-2016 AUP74_RS06755 7b5131c20365d9fade0b072f55e64004 122 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 68 121 7.0E-18 T 11-11-2016 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 AUP74_RS06755 7b5131c20365d9fade0b072f55e64004 122 PRINTS PR01650 Bacterial translocase SecE signature 107 122 3.5E-20 T 11-11-2016 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 AUP74_RS06755 7b5131c20365d9fade0b072f55e64004 122 PRINTS PR01650 Bacterial translocase SecE signature 87 107 3.5E-20 T 11-11-2016 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 AUP74_RS06755 7b5131c20365d9fade0b072f55e64004 122 PRINTS PR01650 Bacterial translocase SecE signature 63 83 3.5E-20 T 11-11-2016 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 AUP74_RS06755 7b5131c20365d9fade0b072f55e64004 122 PRINTS PR01650 Bacterial translocase SecE signature 42 63 3.5E-20 T 11-11-2016 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 AUP74_RS06755 7b5131c20365d9fade0b072f55e64004 122 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 69 119 8.4E-18 T 11-11-2016 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AUP74_RS06755 7b5131c20365d9fade0b072f55e64004 122 Hamap MF_00422 Protein translocase subunit SecE [secE]. 64 121 11.565 T 11-11-2016 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AUP74_RS11110 88f9457393b30c5f57facbe888d1ab78 140 Gene3D G3DSA:3.30.428.10 3 129 3.3E-28 T 11-11-2016 IPR011146 HIT-like domain GO:0003824 AUP74_RS11110 88f9457393b30c5f57facbe888d1ab78 140 Pfam PF01230 HIT domain 11 100 2.8E-18 T 11-11-2016 IPR001310 Histidine triad (HIT) protein AUP74_RS11110 88f9457393b30c5f57facbe888d1ab78 140 SUPERFAMILY SSF54197 4 130 1.7E-31 T 11-11-2016 IPR011146 HIT-like domain GO:0003824 AUP74_RS11110 88f9457393b30c5f57facbe888d1ab78 140 PRINTS PR00332 Histidine triad family signature 4 20 1.0E-9 T 11-11-2016 IPR001310 Histidine triad (HIT) protein AUP74_RS11110 88f9457393b30c5f57facbe888d1ab78 140 PRINTS PR00332 Histidine triad family signature 25 43 1.0E-9 T 11-11-2016 IPR001310 Histidine triad (HIT) protein AUP74_RS11110 88f9457393b30c5f57facbe888d1ab78 140 PRINTS PR00332 Histidine triad family signature 87 97 1.0E-9 T 11-11-2016 IPR001310 Histidine triad (HIT) protein AUP74_RS02900 b5bb83a037218a7b6c012a3b977f2632 445 SUPERFAMILY SSF56601 45 410 2.63E-76 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS02900 b5bb83a037218a7b6c012a3b977f2632 445 Pfam PF00144 Beta-lactamase 51 410 1.8E-66 T 11-11-2016 IPR001466 Beta-lactamase-related AUP74_RS02900 b5bb83a037218a7b6c012a3b977f2632 445 Gene3D G3DSA:3.40.710.10 37 410 6.6E-89 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like AUP74_RS09960 b8d30e0f3cb9c0e4d23a14b982c4e603 105 Gene3D G3DSA:3.30.70.830 1 103 2.0E-46 T 11-11-2016 AUP74_RS09960 b8d30e0f3cb9c0e4d23a14b982c4e603 105 SUPERFAMILY SSF102705 2 102 1.49E-27 T 11-11-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 AUP74_RS05230 939bd068f3d17369a343de13c7b0e642 383 Pfam PF04471 Restriction endonuclease 248 366 1.6E-12 T 11-11-2016 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 AUP74_RS11385 76651378e3864920e5420afc7bc2e691 196 Pfam PF11845 Protein of unknown function (DUF3365) 23 189 1.5E-29 T 11-11-2016 IPR021796 Protein of unknown function DUF3365 AUP74_RS05315 eb3a0877b7246cc176b6feaa8ac351c7 256 Pfam PF12695 Alpha/beta hydrolase family 69 237 5.4E-35 T 11-11-2016 IPR029059 Alpha/beta hydrolase fold-5 AUP74_RS05315 eb3a0877b7246cc176b6feaa8ac351c7 256 Gene3D G3DSA:3.40.50.1820 114 219 1.0E-10 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS05315 eb3a0877b7246cc176b6feaa8ac351c7 256 SUPERFAMILY SSF53474 68 222 2.41E-14 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS03865 f06a68177559703662c56b4076697fc3 526 Hamap MF_00578 Glutamate--cysteine ligase [gshA]. 1 526 202.021 T 11-11-2016 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 AUP74_RS03865 f06a68177559703662c56b4076697fc3 526 TIGRFAM TIGR01434 glu_cys_ligase: glutamate--cysteine ligase 5 516 1.5E-181 T 11-11-2016 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 AUP74_RS03865 f06a68177559703662c56b4076697fc3 526 SUPERFAMILY SSF55931 5 514 7.19E-187 T 11-11-2016 AUP74_RS03865 f06a68177559703662c56b4076697fc3 526 Pfam PF04262 Glutamate-cysteine ligase 5 380 1.7E-160 T 11-11-2016 IPR007370 Glutamate--cysteine ligase GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 AUP74_RS02815 dc3a442ee7653eab358a920885bf2dc8 66 Pfam PF11127 Protein of unknown function (DUF2892) 2 65 6.3E-17 T 11-11-2016 IPR021309 Protein of unknown function DUF2892 AUP74_RS02175 0a1f5336fed3db9dc19ce702a7fa5fa9 779 Pfam PF02470 MlaD protein 47 140 7.6E-7 T 11-11-2016 IPR003399 Mce/MlaD AUP74_RS02175 0a1f5336fed3db9dc19ce702a7fa5fa9 779 Pfam PF02470 MlaD protein 285 351 3.9E-7 T 11-11-2016 IPR003399 Mce/MlaD AUP74_RS02175 0a1f5336fed3db9dc19ce702a7fa5fa9 779 Pfam PF02470 MlaD protein 163 223 3.4E-9 T 11-11-2016 IPR003399 Mce/MlaD AUP74_RS02175 0a1f5336fed3db9dc19ce702a7fa5fa9 779 Pfam PF02470 MlaD protein 399 473 6.3E-8 T 11-11-2016 IPR003399 Mce/MlaD AUP74_RS02175 0a1f5336fed3db9dc19ce702a7fa5fa9 779 Pfam PF02470 MlaD protein 640 699 1.9E-7 T 11-11-2016 IPR003399 Mce/MlaD AUP74_RS02175 0a1f5336fed3db9dc19ce702a7fa5fa9 779 Pfam PF02470 MlaD protein 523 613 2.7E-11 T 11-11-2016 IPR003399 Mce/MlaD AUP74_RS11415 8934cae74c24a53ca66eba1283c2986a 146 Pfam PF13778 Domain of unknown function (DUF4174) 33 143 2.1E-20 T 11-11-2016 IPR025232 Domain of unknown function DUF4174 AUP74_RS12640 724471ef5d8c4e5f9d431877700d5660 373 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 265 276 - T 11-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AUP74_RS12640 724471ef5d8c4e5f9d431877700d5660 373 SUPERFAMILY SSF46548 327 370 5.75E-16 T 11-11-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 AUP74_RS12640 724471ef5d8c4e5f9d431877700d5660 373 SUPERFAMILY SSF46548 251 283 5.75E-16 T 11-11-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 AUP74_RS12640 724471ef5d8c4e5f9d431877700d5660 373 Pfam PF17179 4Fe-4S dicluster domain 264 358 3.0E-33 T 11-11-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AUP74_RS12640 724471ef5d8c4e5f9d431877700d5660 373 Gene3D G3DSA:1.10.1060.10 336 369 2.4E-12 T 11-11-2016 AUP74_RS12640 724471ef5d8c4e5f9d431877700d5660 373 Gene3D G3DSA:1.10.1060.10 255 301 2.4E-12 T 11-11-2016 AUP74_RS12640 724471ef5d8c4e5f9d431877700d5660 373 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 344 355 - T 11-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AUP74_RS11430 6bc6bee2ed9bb4bd700d20b9aaf622d8 145 Pfam PF10861 Protein of Unknown function (DUF2784) 14 133 3.5E-36 T 11-11-2016 IPR021218 Protein of unknown function DUF2784 AUP74_RS05200 39b4f255c78fa26ac2f7a5c313ea1e48 149 Pfam PF16220 Domain of unknown function (DUF4880) 17 57 3.1E-11 T 11-11-2016 IPR032623 FecR, N-terminal AUP74_RS01355 f24a92b93065c2a4b83e243674aed406 142 Pfam PF00011 Hsp20/alpha crystallin family 39 142 5.1E-25 T 11-11-2016 IPR002068 Alpha crystallin/Hsp20 domain AUP74_RS01355 f24a92b93065c2a4b83e243674aed406 142 Gene3D G3DSA:2.60.40.790 11 141 7.0E-43 T 11-11-2016 IPR008978 HSP20-like chaperone AUP74_RS01355 f24a92b93065c2a4b83e243674aed406 142 SUPERFAMILY SSF49764 11 141 8.63E-40 T 11-11-2016 IPR008978 HSP20-like chaperone AUP74_RS01105 522d4b6869afbdf51c1c7103f2b46667 100 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 30 82 4.4E-17 T 11-11-2016 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 AUP74_RS01105 522d4b6869afbdf51c1c7103f2b46667 100 PIRSF PIRSF028784 1 91 4.9E-25 T 11-11-2016 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 AUP74_RS04825 70c134797fbb918c6d5686d1566e1d30 228 PIRSF PIRSF001488 1 227 3.7E-43 T 11-11-2016 IPR023205 Thiol:disulphide interchange protein DsbA/DsbL AUP74_RS04825 70c134797fbb918c6d5686d1566e1d30 228 Pfam PF01323 DSBA-like thioredoxin domain 94 195 1.7E-9 T 11-11-2016 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 AUP74_RS04825 70c134797fbb918c6d5686d1566e1d30 228 ProSitePatterns PS00194 Thioredoxin family active site. 51 69 - T 11-11-2016 IPR017937 Thioredoxin, conserved site GO:0045454 AUP74_RS04825 70c134797fbb918c6d5686d1566e1d30 228 SUPERFAMILY SSF52833 27 214 8.33E-33 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS04825 70c134797fbb918c6d5686d1566e1d30 228 Gene3D G3DSA:3.40.30.10 27 222 1.7E-49 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS01300 20e54fbcb83335e1bacfa05499204128 247 Pfam PF01925 Sulfite exporter TauE/SafE 14 235 1.4E-27 T 11-11-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 AUP74_RS03420 6339d7fc06fb6dcb2bb350d67fcc4e50 427 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 8 340 2.2E-55 T 11-11-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 AUP74_RS03420 6339d7fc06fb6dcb2bb350d67fcc4e50 427 Gene3D G3DSA:3.20.20.70 6 342 2.3E-107 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 AUP74_RS03420 6339d7fc06fb6dcb2bb350d67fcc4e50 427 SUPERFAMILY SSF51395 8 343 1.1E-96 T 11-11-2016 AUP74_RS00125 a966bc0491336d904bbeec4a5827a8cb 382 SUPERFAMILY SSF52540 4 185 3.08E-9 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS08730 30d2c494d3dac60ee4b56dc25c98e124 390 Pfam PF09314 Domain of unknown function (DUF1972) 14 188 5.8E-22 T 11-11-2016 IPR015393 Domain of unknown function DUF1972 AUP74_RS08730 30d2c494d3dac60ee4b56dc25c98e124 390 SUPERFAMILY SSF53756 23 374 1.44E-31 T 11-11-2016 AUP74_RS16635 362070ac5e60bed7bfc4b6269b2de3cd 228 PIRSF PIRSF037290 12 226 1.1E-61 T 11-11-2016 IPR017166 Uncharacterised conserved protein UCP037290 AUP74_RS16635 362070ac5e60bed7bfc4b6269b2de3cd 228 SUPERFAMILY SSF52540 56 173 4.99E-32 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS16635 362070ac5e60bed7bfc4b6269b2de3cd 228 Gene3D G3DSA:3.40.50.300 57 173 2.7E-40 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS08375 97973bada12137c4b6092d19e3a44be5 76 Pfam PF10262 Rdx family 1 62 1.5E-22 T 11-11-2016 IPR011893 Selenoprotein, Rdx type AUP74_RS08375 97973bada12137c4b6092d19e3a44be5 76 Gene3D G3DSA:3.40.30.10 1 75 6.2E-30 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS08375 97973bada12137c4b6092d19e3a44be5 76 TIGRFAM TIGR02174 CXXU_selWTH: selT/selW/selH selenoprotein domain 3 61 6.3E-16 T 11-11-2016 IPR011893 Selenoprotein, Rdx type AUP74_RS08375 97973bada12137c4b6092d19e3a44be5 76 SUPERFAMILY SSF52833 1 71 9.17E-18 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS16630 1e5ed39cdebbf489cf7d20f1dd1c93bc 495 Pfam PF03553 Na+/H+ antiporter family 194 479 1.4E-35 T 11-11-2016 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 AUP74_RS16630 1e5ed39cdebbf489cf7d20f1dd1c93bc 495 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 11 484 1.1E-115 T 11-11-2016 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 AUP74_RS02180 414d64078ac789e8f338378ad228bf19 176 Pfam PF04403 Paraquat-inducible protein A 3 155 4.8E-49 T 11-11-2016 IPR007498 Paraquat-inducible protein A AUP74_RS13030 b7bf89e6c5f32354cfa3e34f7622924c 117 Pfam PF07238 PilZ domain 18 105 3.5E-11 T 11-11-2016 IPR009875 PilZ domain GO:0035438 AUP74_RS08700 820b86b701e3de45a141d679fb01da9f 200 Pfam PF06035 Bacterial transglutaminase-like cysteine proteinase BTLCP 38 147 2.3E-15 T 11-11-2016 IPR010319 Transglutaminase-like cysteine peptidase, predicted AUP74_RS05000 4d7455eef1772d17f3485ec16c1b7dd5 280 Pfam PF00535 Glycosyl transferase family 2 8 137 3.5E-9 T 11-11-2016 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AUP74_RS05000 4d7455eef1772d17f3485ec16c1b7dd5 280 SUPERFAMILY SSF53448 7 215 6.06E-17 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases AUP74_RS05000 4d7455eef1772d17f3485ec16c1b7dd5 280 Gene3D G3DSA:3.90.550.10 8 128 1.5E-9 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases AUP74_RS11310 69ef661fa95b6dfbaaaa2b8449cf3ccb 144 Pfam PF04143 Sulphur transport 9 132 3.0E-7 T 11-11-2016 IPR007272 Sulphur transport domain AUP74_RS11440 6e8aa396b21c3fc03a5f5b15cefb5c45 310 Pfam PF00248 Aldo/keto reductase family 50 295 1.2E-29 T 11-11-2016 IPR023210 NADP-dependent oxidoreductase domain AUP74_RS11440 6e8aa396b21c3fc03a5f5b15cefb5c45 310 SUPERFAMILY SSF51430 40 295 5.76E-48 T 11-11-2016 IPR023210 NADP-dependent oxidoreductase domain AUP74_RS11440 6e8aa396b21c3fc03a5f5b15cefb5c45 310 Gene3D G3DSA:3.20.20.100 42 295 1.2E-43 T 11-11-2016 IPR023210 NADP-dependent oxidoreductase domain AUP74_RS11725 89fdad6a1197065dcd1b4512c1a4258f 412 Gene3D G3DSA:3.40.50.300 4 232 3.4E-6 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11725 89fdad6a1197065dcd1b4512c1a4258f 412 SUPERFAMILY SSF52540 63 214 1.64E-7 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS11725 89fdad6a1197065dcd1b4512c1a4258f 412 SUPERFAMILY SSF52540 3 36 1.64E-7 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase AUP74_RS07000 fb2ec7b6b129904812382bac73af4260 276 Gene3D G3DSA:3.40.50.720 75 215 4.0E-14 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS07000 fb2ec7b6b129904812382bac73af4260 276 SUPERFAMILY SSF51735 12 267 3.13E-30 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS07000 fb2ec7b6b129904812382bac73af4260 276 Pfam PF04321 RmlD substrate binding domain 73 265 3.9E-32 T 11-11-2016 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581 AUP74_RS15375 24e9d8236cf64e04b0a9b31b26beec16 146 Pfam PF16137 Domain of unknown function (DUF4845) 36 120 1.3E-18 T 11-11-2016 IPR032314 Protein of unknown function DUF4845 AUP74_RS05250 8112547493d9d09d4be538499dad8295 619 Pfam PF09369 Domain of unknown function (DUF1998) 481 581 3.4E-9 T 11-11-2016 IPR018973 DEAD/DEAH-box helicase, putative AUP74_RS09765 46ec94a150e1023c307a7277676a320b 154 Pfam PF06127 Protein of unknown function (DUF962) 1 149 2.6E-26 T 11-11-2016 IPR009305 Protein of unknown function DUF962 AUP74_RS10950 551deb274a0668cf75930db62fd36bb7 173 Pfam PF03918 Cytochrome C biogenesis protein 11 157 7.8E-49 T 11-11-2016 IPR005616 CcmH/CycL/Ccl2/NrfF family AUP74_RS10030 ea173e21b783a49b0421fcc13f48ea18 71 Pfam PF06945 Protein of unknown function (DUF1289) 18 63 3.7E-19 T 11-11-2016 IPR010710 Protein of unknown function DUF1289 AUP74_RS04545 2106c000258bbfd47de2aaa784a7de9a 203 Pfam PF01066 CDP-alcohol phosphatidyltransferase 13 76 7.4E-15 T 11-11-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AUP74_RS04545 2106c000258bbfd47de2aaa784a7de9a 203 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 54 76 - T 11-11-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AUP74_RS03170 52aceb6ae384e08df020e198eb39cd9e 118 Pfam PF03724 META domain 26 108 2.3E-12 T 11-11-2016 IPR005184 Domain of unknown function DUF306, Meta/HslJ AUP74_RS11080 b344fe9defa13381f4367a0a049b426c 275 SUPERFAMILY SSF51556 18 271 7.25E-75 T 11-11-2016 IPR032466 Metal-dependent hydrolase AUP74_RS11080 b344fe9defa13381f4367a0a049b426c 275 PIRSF PIRSF005902 2 274 3.8E-66 T 11-11-2016 IPR001130 TatD family GO:0016788 AUP74_RS11080 b344fe9defa13381f4367a0a049b426c 275 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 18 26 - T 11-11-2016 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 AUP74_RS11080 b344fe9defa13381f4367a0a049b426c 275 Gene3D G3DSA:3.20.20.140 16 271 7.1E-76 T 11-11-2016 AUP74_RS11080 b344fe9defa13381f4367a0a049b426c 275 Pfam PF01026 TatD related DNase 19 269 9.2E-63 T 11-11-2016 IPR001130 TatD family GO:0016788 AUP74_RS04600 158dfa85f45912444aef003b7b336b2c 144 SUPERFAMILY SSF54427 2 126 2.54E-5 T 11-11-2016 IPR032710 NTF2-like domain AUP74_RS09335 9f2cb65a32d1e08b3d3c6c0ba6eb0e0c 353 Pfam PF03739 Predicted permease YjgP/YjgQ family 7 351 1.6E-56 T 11-11-2016 IPR005495 Permease LptG/LptF-related GO:0016021 AUP74_RS09335 9f2cb65a32d1e08b3d3c6c0ba6eb0e0c 353 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 4 351 4.3E-113 T 11-11-2016 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 AUP74_RS07590 b163c28c1a46c816b0033433e78df6b8 483 Gene3D G3DSA:3.30.2010.10 57 138 3.8E-20 T 11-11-2016 AUP74_RS07590 b163c28c1a46c816b0033433e78df6b8 483 Pfam PF01435 Peptidase family M48 62 247 3.0E-35 T 11-11-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 AUP74_RS08135 19fbf7f053de3d613b318ffc7de76fb1 188 Pfam PF02472 Biopolymer transport protein ExbD/TolR 9 181 1.6E-15 T 11-11-2016 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 AUP74_RS12570 a1d135d6d9aa2e22fc642e4015a3838f 454 SUPERFAMILY SSF56935 246 454 1.04E-6 T 11-11-2016 AUP74_RS12570 a1d135d6d9aa2e22fc642e4015a3838f 454 SUPERFAMILY SSF56935 50 199 1.04E-6 T 11-11-2016 AUP74_RS12570 a1d135d6d9aa2e22fc642e4015a3838f 454 Pfam PF13372 Alginate export 56 414 3.7E-74 T 11-11-2016 IPR025388 Alginate export domain AUP74_RS11320 78d6cebf3104299146107e22d1d907e1 292 SMART SM00849 19 209 3.5E-24 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS11320 78d6cebf3104299146107e22d1d907e1 292 SUPERFAMILY SSF56281 18 291 3.67E-51 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS11320 78d6cebf3104299146107e22d1d907e1 292 Gene3D G3DSA:3.60.15.10 13 256 4.2E-52 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS11320 78d6cebf3104299146107e22d1d907e1 292 Pfam PF00753 Metallo-beta-lactamase superfamily 19 209 3.6E-22 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS09560 903654f8fd671cbf570d0f0e88dfd477 343 Gene3D G3DSA:2.40.160.50 214 273 9.4E-4 T 11-11-2016 AUP74_RS09560 903654f8fd671cbf570d0f0e88dfd477 343 Pfam PF04338 Protein of unknown function, DUF481 130 343 1.1E-42 T 11-11-2016 IPR007433 Protein of unknown function DUF481 AUP74_RS03790 a77e026f6f73c5aa3c5422a16cf338ad 213 Pfam PF04973 Nicotinamide mononucleotide transporter 18 196 2.0E-47 T 11-11-2016 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 AUP74_RS03790 a77e026f6f73c5aa3c5422a16cf338ad 213 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 19 198 4.7E-20 T 11-11-2016 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 AUP74_RS01740 d59419a19293f46664e15535e6e169d5 400 Pfam PF03773 Predicted permease 8 315 8.0E-56 T 11-11-2016 IPR005524 Predicted permease DUF318 AUP74_RS13555 2b042d243575ec9a5da9b160b0809034 262 Pfam PF05275 Copper resistance protein B precursor (CopB) 56 262 2.8E-75 T 11-11-2016 IPR007939 Copper resistance B precursor GO:0005507|GO:0006878|GO:0009279 AUP74_RS01090 48a1d3f71f9eef840d212d3e902a7aaa 126 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 111 1.4E-29 T 11-11-2016 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 AUP74_RS06585 33ce21c3487a550727694eaf82953938 179 Gene3D G3DSA:3.40.30.10 3 163 1.1E-16 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS06585 33ce21c3487a550727694eaf82953938 179 SUPERFAMILY SSF52833 8 177 1.56E-26 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS06585 33ce21c3487a550727694eaf82953938 179 Pfam PF08534 Redoxin 39 149 1.6E-17 T 11-11-2016 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 AUP74_RS10680 bb6f5cb558871703436033c1e0246ee8 337 Gene3D G3DSA:3.40.630.10 47 192 5.0E-7 T 11-11-2016 AUP74_RS10680 bb6f5cb558871703436033c1e0246ee8 337 SUPERFAMILY SSF53187 13 278 2.98E-35 T 11-11-2016 AUP74_RS10680 bb6f5cb558871703436033c1e0246ee8 337 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 46 156 2.2E-9 T 11-11-2016 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 AUP74_RS00065 6d3df6fa235f565e2d9bcaabb3537b36 1420 Pfam PF13116 Protein of unknown function 573 851 1.9E-32 T 11-11-2016 IPR025263 Domain of unknown function DUF3971 AUP74_RS00065 6d3df6fa235f565e2d9bcaabb3537b36 1420 Pfam PF13502 AsmA-like C-terminal region 1109 1364 6.6E-36 T 11-11-2016 IPR032712 AsmA-like, C-terminal AUP74_RS13085 fe3034719532daa94b318610be314b68 182 Pfam PF02620 Uncharacterized ACR, COG1399 67 176 5.8E-20 T 11-11-2016 IPR003772 Protein of unknown function DUF177 AUP74_RS08850 9e0f1b3c6cda50dedccb50fa73328aeb 279 SUPERFAMILY SSF53448 9 225 1.31E-19 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases AUP74_RS08850 9e0f1b3c6cda50dedccb50fa73328aeb 279 Pfam PF00535 Glycosyl transferase family 2 10 109 4.3E-7 T 11-11-2016 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AUP74_RS08850 9e0f1b3c6cda50dedccb50fa73328aeb 279 Gene3D G3DSA:3.90.550.10 10 131 5.7E-10 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases AUP74_RS10870 bfc941f3ba6951645ddb8ed9f5d6102c 229 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 112 190 1.1E-6 T 11-11-2016 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 AUP74_RS11240 c2313442fd034fedf1ef40fe47f42c8a 261 Pfam PF08241 Methyltransferase domain 86 134 1.8E-10 T 11-11-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 AUP74_RS11240 c2313442fd034fedf1ef40fe47f42c8a 261 SUPERFAMILY SSF53335 87 222 5.18E-15 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS11240 c2313442fd034fedf1ef40fe47f42c8a 261 Gene3D G3DSA:3.40.50.150 89 223 4.0E-12 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS09655 4c21817d000bb313054f40f3091117f3 123 Pfam PF05656 Protein of unknown function (DUF805) 8 112 2.3E-22 T 11-11-2016 IPR008523 Protein of unknown function DUF805 GO:0016021 AUP74_RS11760 848c8e3affc7c6fe2d761df088a753bc 339 Gene3D G3DSA:3.40.50.410 73 274 4.8E-30 T 11-11-2016 IPR002035 von Willebrand factor, type A AUP74_RS11760 848c8e3affc7c6fe2d761df088a753bc 339 Pfam PF00092 von Willebrand factor type A domain 76 272 3.4E-28 T 11-11-2016 IPR002035 von Willebrand factor, type A AUP74_RS11760 848c8e3affc7c6fe2d761df088a753bc 339 SMART SM00327 74 279 3.7E-25 T 11-11-2016 IPR002035 von Willebrand factor, type A AUP74_RS11760 848c8e3affc7c6fe2d761df088a753bc 339 SUPERFAMILY SSF53300 74 256 1.78E-38 T 11-11-2016 IPR002035 von Willebrand factor, type A AUP74_RS03255 eba7b92f0e3f1edad356b8ceddacd405 683 Pfam PF05170 AsmA family 4 535 4.1E-46 T 11-11-2016 IPR007844 AsmA AUP74_RS08935 d845daf6e47de61452b792e6ca8c28f7 183 SUPERFAMILY SSF81342 6 181 2.67E-29 T 11-11-2016 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 AUP74_RS08935 d845daf6e47de61452b792e6ca8c28f7 183 Pfam PF01292 Prokaryotic cytochrome b561 9 178 5.6E-27 T 11-11-2016 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 AUP74_RS07550 c6e20ba122764b633aedec81cad248f3 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 256 8.3E-58 T 11-11-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 AUP74_RS07550 c6e20ba122764b633aedec81cad248f3 259 Gene3D G3DSA:3.90.226.10 6 255 1.8E-77 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS07550 c6e20ba122764b633aedec81cad248f3 259 SUPERFAMILY SSF52096 7 256 2.3E-76 T 11-11-2016 IPR029045 ClpP/crotonase-like domain AUP74_RS09155 72d058c21e0051d7911881b802018ab7 368 Gene3D G3DSA:1.10.260.40 20 85 5.9E-7 T 11-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AUP74_RS09155 72d058c21e0051d7911881b802018ab7 368 Pfam PF13413 Helix-turn-helix domain 28 89 2.0E-19 T 11-11-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 AUP74_RS09155 72d058c21e0051d7911881b802018ab7 368 Pfam PF13464 Domain of unknown function (DUF4115) 293 366 1.9E-16 T 11-11-2016 IPR025194 Domain of unknown function DUF4115 AUP74_RS06640 02d6ccfe3222e176264dd091cdfa1652 369 Pfam PF03702 Uncharacterised protein family (UPF0075) 4 369 2.8E-144 T 11-11-2016 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 AUP74_RS06640 02d6ccfe3222e176264dd091cdfa1652 369 Gene3D G3DSA:3.30.420.40 4 199 6.6E-69 T 11-11-2016 AUP74_RS06640 02d6ccfe3222e176264dd091cdfa1652 369 SUPERFAMILY SSF53067 68 113 1.68E-25 T 11-11-2016 AUP74_RS06640 02d6ccfe3222e176264dd091cdfa1652 369 SUPERFAMILY SSF53067 147 343 1.68E-25 T 11-11-2016 AUP74_RS06640 02d6ccfe3222e176264dd091cdfa1652 369 SUPERFAMILY SSF53067 4 26 1.68E-25 T 11-11-2016 AUP74_RS06640 02d6ccfe3222e176264dd091cdfa1652 369 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 3 369 42.03 T 11-11-2016 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 AUP74_RS15915 ee27f571299f563e6e9ba0779d711773 106 Pfam PF11743 Protein of unknown function (DUF3301) 8 102 4.8E-31 T 11-11-2016 IPR021732 Protein of unknown function DUF3301 AUP74_RS02685 bdcaeb0616f422bc09736f05a4a7b6ae 316 Pfam PF09992 Phosphodiester glycosidase 100 303 1.1E-20 T 11-11-2016 IPR018711 Phosphodiester glycosidase AUP74_RS02200 3fc3ba930d7d0152f49d220c5350d413 303 Gene3D G3DSA:3.90.550.10 3 219 9.8E-28 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases AUP74_RS02200 3fc3ba930d7d0152f49d220c5350d413 303 Pfam PF00535 Glycosyl transferase family 2 6 143 1.4E-16 T 11-11-2016 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AUP74_RS02200 3fc3ba930d7d0152f49d220c5350d413 303 SUPERFAMILY SSF53448 5 231 1.5E-38 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases AUP74_RS16475 8dd702bd06c72af819d0b2a3f438a120 220 Pfam PF14015 Protein of unknown function (DUF4231) 38 115 2.2E-5 T 11-11-2016 IPR025325 Protein of unknown function DUF4231 AUP74_RS16135 4b49b2c77e7a80d9acdf999a39424f99 245 TIGRFAM TIGR04219 OMP_w_GlyGly: outer membrane protein 3 244 3.2E-68 T 11-11-2016 IPR026387 Outer membrane protein AUP74_RS14390 bdaf88087c23dc9370e13ab1f1041f17 299 SUPERFAMILY SSF88713 4 284 1.11E-71 T 11-11-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AUP74_RS14390 bdaf88087c23dc9370e13ab1f1041f17 299 Gene3D G3DSA:3.20.20.370 4 285 1.5E-78 T 11-11-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 AUP74_RS14390 bdaf88087c23dc9370e13ab1f1041f17 299 Pfam PF01522 Polysaccharide deacetylase 60 169 1.1E-17 T 11-11-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 AUP74_RS08130 7a8acf125c3604f356ed5566d0f708a6 196 Pfam PF02472 Biopolymer transport protein ExbD/TolR 10 166 8.8E-14 T 11-11-2016 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 AUP74_RS02350 3178f801958e10fa5b0f71fdfac67bd1 273 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 9 255 2.2E-78 T 11-11-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 AUP74_RS02350 3178f801958e10fa5b0f71fdfac67bd1 273 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 138 150 - T 11-11-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 AUP74_RS02350 3178f801958e10fa5b0f71fdfac67bd1 273 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 6 260 19.513 T 11-11-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 AUP74_RS02350 3178f801958e10fa5b0f71fdfac67bd1 273 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 3 260 4.7E-81 T 11-11-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 AUP74_RS01930 3bb4e8af00bb93b087ebc992261588d7 235 Pfam PF01863 Protein of unknown function DUF45 23 228 2.7E-48 T 11-11-2016 IPR002725 Protein of unknown function DUF45 AUP74_RS09855 200f8a5cf1e04847d32ac37403ca875a 631 Pfam PF05960 Bacterial protein of unknown function (DUF885) 79 620 3.0E-184 T 11-11-2016 IPR010281 Protein of unknown function DUF885 AUP74_RS15900 6db45a90dd234128be3aaa7f24c794fa 65 Pfam PF13490 Putative zinc-finger 4 38 1.7E-7 T 11-11-2016 IPR027383 Putative zinc-finger AUP74_RS03350 09a41763eb21b364e37a678e92a968e0 640 Pfam PF13091 PLD-like domain 49 143 2.0E-6 T 11-11-2016 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 AUP74_RS05740 4e5b709d56c9b32b7da93f20589a0bf4 176 Pfam PF04351 Pilus assembly protein, PilP 25 170 4.1E-48 T 11-11-2016 IPR007446 Pilus assembly protein PilP AUP74_RS05740 4e5b709d56c9b32b7da93f20589a0bf4 176 PIRSF PIRSF016481 2 174 7.8E-46 T 11-11-2016 IPR007446 Pilus assembly protein PilP AUP74_RS05905 c012bfd1b108943011d3dd6cc96443e5 824 Pfam PF00577 Outer membrane usher protein 284 714 1.0E-5 T 11-11-2016 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 AUP74_RS11405 80469a463440c7889bf49ebb59a5e844 220 Gene3D G3DSA:3.40.50.720 3 200 1.1E-38 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS11405 80469a463440c7889bf49ebb59a5e844 220 SUPERFAMILY SSF51735 3 201 7.58E-36 T 11-11-2016 IPR016040 NAD(P)-binding domain AUP74_RS11405 80469a463440c7889bf49ebb59a5e844 220 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 118 3.9E-6 T 11-11-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 AUP74_RS07380 af90fb358583cd3efce2bbd59833d4f2 84 Pfam PF09932 Uncharacterized conserved protein (DUF2164) 4 77 1.0E-27 T 11-11-2016 IPR018680 Protein of unknown function DUF2164 AUP74_RS13135 698ef4d351dcec4fbe55997a78ca5178 236 Pfam PF09335 SNARE associated Golgi protein 65 182 1.7E-28 T 11-11-2016 IPR032816 SNARE associated Golgi protein AUP74_RS05410 8c51de7209a0d5398f8ad86e6eaffc11 241 TIGRFAM TIGR02001 gcw_chp: conserved hypothetical protein 6 240 2.1E-51 T 11-11-2016 IPR010239 Conserved hypothetical protein CHP02001 AUP74_RS05410 8c51de7209a0d5398f8ad86e6eaffc11 241 Pfam PF09694 Bacterial protein of unknown function (Gcw_chp) 28 220 1.6E-30 T 11-11-2016 IPR010239 Conserved hypothetical protein CHP02001 AUP74_RS12690 3ff359c3e9f6a0bac6964aed7a165829 237 Pfam PF02535 ZIP Zinc transporter 77 234 2.2E-33 T 11-11-2016 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 AUP74_RS13080 40bdf63d98a68a68c0793eedfaf56cbb 63 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 56 6.6E-19 T 11-11-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS13080 40bdf63d98a68a68c0793eedfaf56cbb 63 Pfam PF01783 Ribosomal L32p protein family 2 56 4.0E-20 T 11-11-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS13080 40bdf63d98a68a68c0793eedfaf56cbb 63 SUPERFAMILY SSF57829 2 57 5.07E-19 T 11-11-2016 IPR011332 Zinc-binding ribosomal protein GO:0006412 AUP74_RS13080 40bdf63d98a68a68c0793eedfaf56cbb 63 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 55 16.687 T 11-11-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AUP74_RS04165 c36dffd50d247f281d041f58c41e5e01 211 Pfam PF06080 Protein of unknown function (DUF938) 10 199 1.7E-68 T 11-11-2016 IPR010342 Protein of unknown function DUF938 AUP74_RS04165 c36dffd50d247f281d041f58c41e5e01 211 SUPERFAMILY SSF53335 18 194 2.76E-26 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS04165 c36dffd50d247f281d041f58c41e5e01 211 Gene3D G3DSA:3.40.50.150 18 198 1.2E-16 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AUP74_RS13810 959052ec4148e1ea9b4418735b6d4f1d 448 SUPERFAMILY SSF51569 2 443 4.54E-203 T 11-11-2016 AUP74_RS13810 959052ec4148e1ea9b4418735b6d4f1d 448 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 2 444 7.2E-218 T 11-11-2016 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 AUP74_RS13810 959052ec4148e1ea9b4418735b6d4f1d 448 Pfam PF01474 Class-II DAHP synthetase family 2 439 1.1E-208 T 11-11-2016 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 AUP74_RS05635 a3dd897da18abcd6a99b49e29cc35c45 196 Pfam PF12915 Protein of unknown function (DUF3833) 19 184 4.3E-55 T 11-11-2016 IPR024409 Protein of unknown function DUF3833 AUP74_RS00675 f2667e66d396ef2defcceb5cf98e963d 240 SMART SM00702 20 234 0.0029 T 11-11-2016 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 AUP74_RS00675 f2667e66d396ef2defcceb5cf98e963d 240 Pfam PF13661 2OG-Fe(II) oxygenase superfamily 142 234 2.0E-24 T 11-11-2016 AUP74_RS16170 8f4f6fa1ba845aaafb3147931548eb8b 176 Pfam PF14333 Domain of unknown function (DUF4389) 14 87 3.4E-28 T 11-11-2016 IPR025498 Protein of unknown function DUF4389 AUP74_RS15200 8303e24121952e5ebd1c301a96638fae 190 Pfam PF07209 Protein of unknown function (DUF1415) 7 173 6.5E-66 T 11-11-2016 IPR009858 Protein of unknown function DUF1415 AUP74_RS06305 7b05dc2054658863f26f294dd51ab733 138 Pfam PF01219 Prokaryotic diacylglycerol kinase 31 132 4.7E-34 T 11-11-2016 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039 AUP74_RS06305 7b05dc2054658863f26f294dd51ab733 138 Gene3D G3DSA:1.10.3830.10 19 136 4.7E-44 T 11-11-2016 AUP74_RS09480 872b3a931d4f7bc04a3ec5d682bf6d9a 174 Pfam PF05751 FixH 11 159 2.3E-29 T 11-11-2016 IPR008620 Nitrogen fixation protein FixH AUP74_RS03290 a0586d7ab4f5dfc4fbe437273af9f2d0 223 SUPERFAMILY SSF53041 3 145 3.92E-23 T 11-11-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AUP74_RS03290 a0586d7ab4f5dfc4fbe437273af9f2d0 223 ProSitePatterns PS00397 Site-specific recombinases active site. 7 15 - T 11-11-2016 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 AUP74_RS03290 a0586d7ab4f5dfc4fbe437273af9f2d0 223 Gene3D G3DSA:3.40.50.1390 3 128 1.8E-15 T 11-11-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AUP74_RS03290 a0586d7ab4f5dfc4fbe437273af9f2d0 223 Pfam PF00239 Resolvase, N terminal domain 5 144 3.5E-20 T 11-11-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AUP74_RS03290 a0586d7ab4f5dfc4fbe437273af9f2d0 223 SMART SM00857 4 145 7.9E-29 T 11-11-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AUP74_RS11595 2c99804507137afe88a1e7e3a4be8287 62 Pfam PF11216 Protein of unknown function (DUF3012) 25 55 5.2E-15 T 11-11-2016 IPR021379 Protein of unknown function DUF3012 AUP74_RS07285 83913a3bcc5ee5ee44ce24709164aef0 205 Pfam PF04519 Polymer-forming cytoskeletal 42 139 1.9E-21 T 11-11-2016 IPR007607 Protein of unknown function DUF583 AUP74_RS07885 a3ee60586414f5fcdede7516cd60295d 133 Pfam PF14248 Domain of unknown function (DUF4345) 7 119 2.2E-9 T 11-11-2016 IPR025597 Protein of unknown function DUF4345 AUP74_RS14115 a478d649e44c5a872dc64710616b2778 365 Gene3D G3DSA:2.40.50.100 159 190 1.1E-9 T 11-11-2016 AUP74_RS14115 a478d649e44c5a872dc64710616b2778 365 Gene3D G3DSA:2.40.50.100 65 98 1.1E-9 T 11-11-2016 AUP74_RS14115 a478d649e44c5a872dc64710616b2778 365 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 64 268 2.5E-8 T 11-11-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AUP74_RS14115 a478d649e44c5a872dc64710616b2778 365 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 40 349 7.7E-72 T 11-11-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 AUP74_RS14115 a478d649e44c5a872dc64710616b2778 365 SUPERFAMILY SSF111369 55 272 2.88E-28 T 11-11-2016 AUP74_RS09465 a17c20b8d8581e9be3141aa9f67cf04f 88 Pfam PF05545 Cbb3-type cytochrome oxidase component FixQ 3 45 5.7E-8 T 11-11-2016 IPR008621 Cbb3-type cytochrome oxidase component AUP74_RS11900 15139a1344e3f4499fb70608aefbb0a3 258 Pfam PF10972 Peptidoglycan-binding protein, CsiV 11 245 3.4E-37 T 11-11-2016 IPR021241 Peptidoglycan-binding protein, CsiV AUP74_RS14020 df06ec3d917c94a6478808744d86b5f3 198 Pfam PF13529 Peptidase_C39 like family 27 152 1.7E-12 T 11-11-2016 AUP74_RS08510 6668fcb0d3fa73f370cd7200971dc383 393 Pfam PF06580 Histidine kinase 180 260 1.7E-24 T 11-11-2016 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 AUP74_RS08510 6668fcb0d3fa73f370cd7200971dc383 393 SUPERFAMILY SSF55874 236 374 8.08E-13 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS08510 6668fcb0d3fa73f370cd7200971dc383 393 Gene3D G3DSA:3.30.565.10 234 377 5.2E-12 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain AUP74_RS08585 3e3736761ae90f4c2623ee324048bf7c 380 SUPERFAMILY SSF56935 68 380 5.86E-24 T 11-11-2016 AUP74_RS08585 3e3736761ae90f4c2623ee324048bf7c 380 SUPERFAMILY SSF56935 14 39 5.86E-24 T 11-11-2016 AUP74_RS15145 1cc6f31c0918047ff5a92ab4baeb0abd 155 Gene3D G3DSA:3.40.630.30 15 152 7.5E-21 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS15145 1cc6f31c0918047ff5a92ab4baeb0abd 155 SUPERFAMILY SSF55729 24 139 1.96E-24 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase AUP74_RS15145 1cc6f31c0918047ff5a92ab4baeb0abd 155 Pfam PF13508 Acetyltransferase (GNAT) domain 52 133 1.1E-11 T 11-11-2016 IPR000182 GNAT domain GO:0008080 AUP74_RS02560 ce53bd00439ac244229814a776513f3b 62 SUPERFAMILY SSF51316 6 46 1.99E-5 T 11-11-2016 IPR011057 Mss4-like AUP74_RS02560 ce53bd00439ac244229814a776513f3b 62 Gene3D G3DSA:3.90.1590.10 6 48 1.5E-4 T 11-11-2016 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 AUP74_RS01920 b6bf77ca2c6cd305e9c6c2b1141bdfc5 122 Pfam PF11042 Protein of unknown function (DUF2750) 16 117 6.7E-34 T 11-11-2016 IPR021284 Protein of unknown function DUF2750 AUP74_RS15875 982dc8e729405e8a3e8902b46d251dd7 196 Pfam PF07273 Protein of unknown function (DUF1439) 45 188 2.5E-20 T 11-11-2016 IPR010835 Protein of unknown function DUF1439 AUP74_RS13360 1bcae11089c6750545d7580ee572b6b9 206 Pfam PF03458 UPF0126 domain 92 164 2.5E-19 T 11-11-2016 IPR005115 Uncharacterised domain UPF0126 AUP74_RS13360 1bcae11089c6750545d7580ee572b6b9 206 Pfam PF03458 UPF0126 domain 6 79 4.5E-23 T 11-11-2016 IPR005115 Uncharacterised domain UPF0126 AUP74_RS16370 6c26af647d70629566aca755ee289988 158 Gene3D G3DSA:3.40.1280.10 5 155 2.5E-35 T 11-11-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AUP74_RS16370 6c26af647d70629566aca755ee289988 158 SUPERFAMILY SSF75217 4 155 3.01E-32 T 11-11-2016 IPR029028 Alpha/beta knot methyltransferases AUP74_RS16370 6c26af647d70629566aca755ee289988 158 Pfam PF00588 SpoU rRNA Methylase family 10 149 4.3E-27 T 11-11-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 AUP74_RS08060 f2900d72d28a37854f3782af0b8b1d8d 100 SMART SM01103 3 86 1.9E-32 T 11-11-2016 IPR001890 RNA-binding, CRM domain GO:0003723 AUP74_RS08060 f2900d72d28a37854f3782af0b8b1d8d 100 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 11 86 1.0E-21 T 11-11-2016 IPR001890 RNA-binding, CRM domain GO:0003723 AUP74_RS08060 f2900d72d28a37854f3782af0b8b1d8d 100 Gene3D G3DSA:3.30.110.60 1 94 6.6E-27 T 11-11-2016 IPR001890 RNA-binding, CRM domain GO:0003723 AUP74_RS08060 f2900d72d28a37854f3782af0b8b1d8d 100 SUPERFAMILY SSF75471 1 94 9.55E-27 T 11-11-2016 IPR001890 RNA-binding, CRM domain GO:0003723 AUP74_RS08060 f2900d72d28a37854f3782af0b8b1d8d 100 Pfam PF01985 CRS1 / YhbY (CRM) domain 3 86 1.0E-18 T 11-11-2016 IPR001890 RNA-binding, CRM domain GO:0003723 AUP74_RS14580 9976e07ea043ecb92653b5a72ddbe837 152 SMART SM00903 7 150 4.2E-52 T 11-11-2016 IPR002563 Flavin reductase like domain GO:0010181 AUP74_RS14580 9976e07ea043ecb92653b5a72ddbe837 152 Gene3D G3DSA:2.30.110.10 2 149 2.5E-53 T 11-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 AUP74_RS14580 9976e07ea043ecb92653b5a72ddbe837 152 Pfam PF01613 Flavin reductase like domain 8 151 7.6E-36 T 11-11-2016 IPR002563 Flavin reductase like domain GO:0010181 AUP74_RS14580 9976e07ea043ecb92653b5a72ddbe837 152 SUPERFAMILY SSF50475 2 150 6.87E-46 T 11-11-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 AUP74_RS04425 d5b07bf1946fe7565ac5d6b685fbc111 120 Pfam PF03899 ATP synthase I chain 8 105 3.7E-21 T 11-11-2016 IPR005598 ATP synthase protein I AUP74_RS02265 492dc38d545ea7764e3b7ec682ce1b91 424 Pfam PF01384 Phosphate transporter family 26 411 7.7E-123 T 11-11-2016 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 AUP74_RS14175 997298045c7a04996184ec137b698afa 87 Gene3D G3DSA:3.90.25.10 11 83 6.9E-4 T 11-11-2016 AUP74_RS02550 ef565c924dd4b4c253f84c91d5b9ce0a 124 SUPERFAMILY SSF54427 1 114 1.44E-12 T 11-11-2016 IPR032710 NTF2-like domain AUP74_RS02550 ef565c924dd4b4c253f84c91d5b9ce0a 124 Pfam PF12680 SnoaL-like domain 8 99 3.4E-6 T 11-11-2016 IPR009959 Polyketide cyclase SnoaL-like domain AUP74_RS02550 ef565c924dd4b4c253f84c91d5b9ce0a 124 Gene3D G3DSA:3.10.450.50 2 117 1.5E-12 T 11-11-2016 IPR032710 NTF2-like domain AUP74_RS01940 1b55c46ad13ff403f9b0ec55e93f0876 195 Pfam PF10973 Protein of unknown function (DUF2799) 40 122 1.1E-22 T 11-11-2016 IPR021242 Protein of unknown function DUF2799 AUP74_RS10005 0622e2ab46d243a88fef8aa87f605c40 564 Pfam PF03571 Peptidase family M49 182 395 9.4E-15 T 11-11-2016 AUP74_RS06815 d9ffed1a1bc33bb7dd98fa5b5675ec66 158 SUPERFAMILY SSF55826 7 149 2.35E-30 T 11-11-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 AUP74_RS06815 d9ffed1a1bc33bb7dd98fa5b5675ec66 158 Pfam PF04073 Aminoacyl-tRNA editing domain 23 142 1.5E-22 T 11-11-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 AUP74_RS06815 d9ffed1a1bc33bb7dd98fa5b5675ec66 158 Gene3D G3DSA:3.90.960.10 7 152 2.1E-24 T 11-11-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 AUP74_RS09730 6e0248bf29fefcab6268f8ceaa2ec5d0 813 Pfam PF02687 FtsX-like permease family 251 368 3.5E-10 T 11-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 AUP74_RS09730 6e0248bf29fefcab6268f8ceaa2ec5d0 813 Pfam PF02687 FtsX-like permease family 692 799 3.3E-10 T 11-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 AUP74_RS02825 30258c10ed92e71fc43bcda8db486f81 250 Pfam PF03741 Integral membrane protein TerC family 16 203 1.2E-49 T 11-11-2016 IPR005496 Integral membrane protein TerC GO:0016021 AUP74_RS05360 128e99066c94467ca21820b0fbedb47c 73 Pfam PF12088 Protein of unknown function (DUF3565) 7 62 2.4E-33 T 11-11-2016 IPR021948 Protein of unknown function DUF3565 AUP74_RS12130 5677a61f89540bd7ee2348dc91bad09b 237 Pfam PF14145 YrhK-like protein 26 78 6.5E-12 T 11-11-2016 IPR025424 YrhK domain AUP74_RS12130 5677a61f89540bd7ee2348dc91bad09b 237 Pfam PF14145 YrhK-like protein 98 151 3.5E-10 T 11-11-2016 IPR025424 YrhK domain AUP74_RS12130 5677a61f89540bd7ee2348dc91bad09b 237 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 24 177 1.0E-4 T 11-11-2016 AUP74_RS16390 2911324cf12f1d7ec06931bfeae001d3 303 Pfam PF13557 Putative MetA-pathway of phenol degradation 69 286 1.9E-14 T 11-11-2016 IPR025737 MetA-pathway of phenol degradation, putative AUP74_RS04720 bb015fa018b04f7c18b19ce2668c7a78 343 Pfam PF02628 Cytochrome oxidase assembly protein 16 324 1.9E-79 T 11-11-2016 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 AUP74_RS11770 037d021641a1f75ead77523b0da461c0 333 Pfam PF01882 Protein of unknown function DUF58 56 140 1.3E-23 T 11-11-2016 IPR002881 Domain of unknown function DUF58 AUP74_RS05015 ffc8252fcb6f9236442f290437778248 446 Pfam PF04422 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term 91 161 6.7E-13 T 11-11-2016 IPR007516 Coenzyme F420 hydrogenase/dehydrogenase beta subunit, N-terminal AUP74_RS05015 ffc8252fcb6f9236442f290437778248 446 Pfam PF04432 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus 177 338 3.5E-33 T 11-11-2016 IPR007525 Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal AUP74_RS14495 212c32be0de8270188811b6af9c6256e 258 PIRSF PIRSF015736 1 258 4.5E-53 T 11-11-2016 IPR026286 Maleate isomerase/Arylmalonate decarboxylase AUP74_RS11340 742c95d78c5f995e17fb6556132b179a 356 Pfam PF00487 Fatty acid desaturase 101 307 3.5E-23 T 11-11-2016 IPR005804 Fatty acid desaturase domain GO:0006629 AUP74_RS09810 d4c0fd1a8c492a85645cf3a7d7d6ff78 228 Pfam PF11306 Protein of unknown function (DUF3108) 14 217 3.4E-26 T 11-11-2016 IPR021457 Protein of unknown function DUF3108 AUP74_RS02320 7f12b323be4f3c7b6438e914c48d8dc7 133 Pfam PF02472 Biopolymer transport protein ExbD/TolR 11 132 1.1E-24 T 11-11-2016 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 AUP74_RS02065 64ad27ebb81e599f4506c9c1984aaab4 276 Pfam PF11219 Protein of unknown function (DUF3014) 109 265 5.5E-47 T 11-11-2016 IPR021382 Protein of unknown function DUF3014 AUP74_RS03475 3f8660a80443d1d098af0f363df291cb 93 SUPERFAMILY SSF143100 1 64 8.89E-11 T 11-11-2016 AUP74_RS03475 3f8660a80443d1d098af0f363df291cb 93 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 3 86 4.4E-17 T 11-11-2016 IPR031807 HicB-like antitoxin of toxin-antitoxin system AUP74_RS03495 9e4c5a168a5b52d8bd6e6236d8cf26a2 220 Pfam PF07947 YhhN-like protein 41 214 7.6E-34 T 11-11-2016 IPR012506 YhhN-like GO:0016021 AUP74_RS07605 73d2a5212d00f523b1446166956110bc 334 SUPERFAMILY SSF53300 156 296 8.09E-10 T 11-11-2016 IPR002035 von Willebrand factor, type A AUP74_RS02330 3c9bfe7f52996ac78e5805d80e38cb24 460 PIRSF PIRSF037714 6 460 3.6E-168 T 11-11-2016 IPR017270 Putative MotA/TolQ/ExbB family protein AUP74_RS02330 3c9bfe7f52996ac78e5805d80e38cb24 460 Pfam PF01618 MotA/TolQ/ExbB proton channel family 326 446 2.0E-30 T 11-11-2016 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 AUP74_RS08310 ec880cf0a5ac8181d959f85c3cd6156f 94 Gene3D G3DSA:1.10.150.20 6 86 1.1E-21 T 11-11-2016 AUP74_RS08310 ec880cf0a5ac8181d959f85c3cd6156f 94 Pfam PF04994 TfoX C-terminal domain 5 83 3.5E-23 T 11-11-2016 IPR007077 TfoX, C-terminal AUP74_RS13050 c2d1f6f76fa53a14ed494d126824f90a 256 Pfam PF01063 Amino-transferase class IV 25 231 6.9E-25 T 11-11-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 AUP74_RS13050 c2d1f6f76fa53a14ed494d126824f90a 256 SUPERFAMILY SSF56752 22 236 1.57E-33 T 11-11-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 AUP74_RS13050 c2d1f6f76fa53a14ed494d126824f90a 256 Gene3D G3DSA:3.20.10.10 107 251 1.8E-27 T 11-11-2016 AUP74_RS08440 41bf967c150f7e3f5b0cdc386e809139 375 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 24 370 3.7E-125 T 11-11-2016 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 AUP74_RS08440 41bf967c150f7e3f5b0cdc386e809139 375 Pfam PF01098 Cell cycle protein 28 371 2.0E-103 T 11-11-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 AUP74_RS05510 70c5917b6681f3200799ee32761c0ed5 202 Pfam PF02325 YGGT family 110 178 4.5E-13 T 11-11-2016 IPR003425 CCB3/YggT GO:0016020 AUP74_RS05510 70c5917b6681f3200799ee32761c0ed5 202 Pfam PF02325 YGGT family 19 81 7.2E-15 T 11-11-2016 IPR003425 CCB3/YggT GO:0016020 AUP74_RS03640 4281155c0c65d773df09c0be4e63fe38 250 Pfam PF01988 VIT family 32 241 4.8E-50 T 11-11-2016 IPR008217 Ccc1 family AUP74_RS07775 fce96d4c586fe102b53fe88ea0794b9c 94 Pfam PF05957 Bacterial protein of unknown function (DUF883) 15 90 2.4E-11 T 11-11-2016 IPR010279 Protein of unknown function DUF883, ElaB AUP74_RS16470 48191e468ca2eb61ed412940360f6b10 448 Pfam PF03553 Na+/H+ antiporter family 15 210 1.2E-17 T 11-11-2016 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 AUP74_RS02780 5059b63818bc03027661cc633b05f63f 97 SUPERFAMILY SSF54909 1 96 4.69E-20 T 11-11-2016 IPR011008 Dimeric alpha-beta barrel AUP74_RS02780 5059b63818bc03027661cc633b05f63f 97 Gene3D G3DSA:3.30.70.900 40 94 2.2E-9 T 11-11-2016 AUP74_RS03655 e9cd35ce474e7036061fea9976215b6a 385 SUPERFAMILY SSF50952 38 383 6.02E-38 T 11-11-2016 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 AUP74_RS03655 e9cd35ce474e7036061fea9976215b6a 385 Gene3D G3DSA:2.120.10.30 37 383 3.1E-81 T 11-11-2016 IPR011042 Six-bladed beta-propeller, TolB-like AUP74_RS03655 e9cd35ce474e7036061fea9976215b6a 385 Pfam PF07995 Glucose / Sorbosone dehydrogenase 49 380 5.1E-108 T 11-11-2016 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 AUP74_RS00955 9352054273dab30ea7ac401990d1603d 114 Pfam PF04355 SmpA / OmlA family 36 101 6.3E-27 T 11-11-2016 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 AUP74_RS00955 9352054273dab30ea7ac401990d1603d 114 Hamap MF_00925 Outer membrane protein assembly factor BamE [bamE]. 4 113 26.99 T 11-11-2016 IPR026592 Outer membrane protein assembly factor BamE AUP74_RS12460 b66ee4ed28ac8d5daad2c9afc9e3c39c 564 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 212 238 2.1E-5 T 11-11-2016 AUP74_RS12460 b66ee4ed28ac8d5daad2c9afc9e3c39c 564 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 64 89 2.1E-5 T 11-11-2016 AUP74_RS12460 b66ee4ed28ac8d5daad2c9afc9e3c39c 564 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 273 285 2.1E-5 T 11-11-2016 AUP74_RS12460 b66ee4ed28ac8d5daad2c9afc9e3c39c 564 Pfam PF00361 Proton-conducting membrane transporter 110 381 2.7E-41 T 11-11-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS09205 bfa3ee19ab5f811f5deb7ad526bbdf82 204 SUPERFAMILY SSF52833 23 204 1.14E-35 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS09205 bfa3ee19ab5f811f5deb7ad526bbdf82 204 Pfam PF00578 AhpC/TSA family 29 155 2.3E-16 T 11-11-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AUP74_RS09205 bfa3ee19ab5f811f5deb7ad526bbdf82 204 Gene3D G3DSA:3.40.30.10 14 162 3.6E-26 T 11-11-2016 IPR012336 Thioredoxin-like fold AUP74_RS15190 75e332564283c2ce11383059eff67f69 534 Pfam PF03806 AbgT putative transporter family 24 531 1.3E-217 T 11-11-2016 IPR004697 p-aminobenzoyl-glutamate transport protein AbgT GO:0015558|GO:1902604 AUP74_RS00800 0ec470b7a73b896c5d905c5e8c48dae9 401 Pfam PF12704 MacB-like periplasmic core domain 82 245 2.5E-9 T 11-11-2016 IPR025857 MacB-like periplasmic core domain AUP74_RS00800 0ec470b7a73b896c5d905c5e8c48dae9 401 Pfam PF02687 FtsX-like permease family 283 394 9.0E-15 T 11-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 AUP74_RS05900 af7a380d3ef6e3746e0a320dff96ec7e 235 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 27 140 2.5E-6 T 11-11-2016 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 AUP74_RS05900 af7a380d3ef6e3746e0a320dff96ec7e 235 SUPERFAMILY SSF49354 26 141 2.62E-8 T 11-11-2016 IPR008962 PapD-like AUP74_RS02070 ceaa7ce75428b72e2a4e4ac43498f222 241 Gene3D G3DSA:3.40.50.1110 46 234 2.2E-18 T 11-11-2016 IPR013830 SGNH hydrolase-type esterase domain AUP74_RS02070 ceaa7ce75428b72e2a4e4ac43498f222 241 SUPERFAMILY SSF52266 44 232 2.75E-25 T 11-11-2016 IPR013830 SGNH hydrolase-type esterase domain AUP74_RS02070 ceaa7ce75428b72e2a4e4ac43498f222 241 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 50 219 4.1E-13 T 11-11-2016 IPR013830 SGNH hydrolase-type esterase domain AUP74_RS13155 93b3f2853b69b8ee0379b14ab119d966 226 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 19 220 2.3E-42 T 11-11-2016 AUP74_RS02595 f14e3e451af90065d942e078027fae1e 259 Gene3D G3DSA:2.40.230.20 17 259 8.2E-64 T 11-11-2016 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 AUP74_RS02595 f14e3e451af90065d942e078027fae1e 259 SUPERFAMILY SSF111364 22 259 4.05E-62 T 11-11-2016 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 AUP74_RS02595 f14e3e451af90065d942e078027fae1e 259 Pfam PF03502 Nucleoside-specific channel-forming protein, Tsx 45 259 9.7E-20 T 11-11-2016 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 AUP74_RS04300 5c207dccf8178520fcf712f0e1e1c621 132 Pfam PF07681 DoxX 11 89 2.6E-19 T 11-11-2016 IPR032808 DoxX family AUP74_RS12440 11af8d2e2c558c34ee936a038bc6718e 117 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 10 110 1.5E-25 T 11-11-2016 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 AUP74_RS13395 9670571d39b11e9b67521a33d773fd0a 417 Gene3D G3DSA:2.40.160.10 42 415 2.7E-26 T 11-11-2016 IPR023614 Porin domain AUP74_RS13395 9670571d39b11e9b67521a33d773fd0a 417 SUPERFAMILY SSF56935 39 414 1.31E-22 T 11-11-2016 AUP74_RS15005 df3184841bac3bf5447576b3c3e8de28 390 SUPERFAMILY SSF53383 25 385 1.14E-29 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase AUP74_RS15005 df3184841bac3bf5447576b3c3e8de28 390 Gene3D G3DSA:3.40.640.10 37 277 3.5E-18 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 AUP74_RS13370 18229f933dc7e5741324dc91c904b056 367 SUPERFAMILY SSF56935 3 357 4.49E-15 T 11-11-2016 AUP74_RS01805 f3f1a258bf7b1b17263dd8dbb61c2f76 488 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 4 474 42.924 T 11-11-2016 IPR003846 Uncharacterised protein family UPF0061 AUP74_RS01805 f3f1a258bf7b1b17263dd8dbb61c2f76 488 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 7 457 1.0E-145 T 11-11-2016 IPR003846 Uncharacterised protein family UPF0061 AUP74_RS07695 d747f65e15089d195555911fc4b5ea62 235 SUPERFAMILY SSF46689 20 91 1.08E-12 T 11-11-2016 IPR009057 Homeodomain-like GO:0003677 AUP74_RS07695 d747f65e15089d195555911fc4b5ea62 235 Gene3D G3DSA:1.10.357.10 24 223 4.1E-29 T 11-11-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 AUP74_RS07695 d747f65e15089d195555911fc4b5ea62 235 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 72 1.4E-4 T 11-11-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AUP74_RS00135 1a1334e736e48171cf6b058feb41f6f6 211 Pfam PF07681 DoxX 23 108 3.8E-19 T 11-11-2016 IPR032808 DoxX family AUP74_RS03555 c5096cc8ccdecbd2cc5479dda0cbc301 254 Gene3D G3DSA:3.40.50.1110 44 228 5.1E-4 T 11-11-2016 IPR013830 SGNH hydrolase-type esterase domain AUP74_RS03555 c5096cc8ccdecbd2cc5479dda0cbc301 254 SUPERFAMILY SSF52266 25 235 4.43E-40 T 11-11-2016 IPR013830 SGNH hydrolase-type esterase domain AUP74_RS03555 c5096cc8ccdecbd2cc5479dda0cbc301 254 Pfam PF03629 Carbohydrate esterase, sialic acid-specific acetylesterase 114 230 1.2E-10 T 11-11-2016 IPR005181 Sialate O-acetylesterase domain AUP74_RS05715 c173543c4409b50ddcb7ef4afc78d19c 160 Pfam PF01584 CheW-like domain 18 122 2.7E-9 T 11-11-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 AUP74_RS05715 c173543c4409b50ddcb7ef4afc78d19c 160 SUPERFAMILY SSF50341 14 128 1.96E-10 T 11-11-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 AUP74_RS12015 bc367962111e7e8d0be22ccb89f59e92 413 Pfam PF02687 FtsX-like permease family 273 406 3.4E-19 T 11-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 AUP74_RS12015 bc367962111e7e8d0be22ccb89f59e92 413 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 5 413 1.3E-141 T 11-11-2016 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 AUP74_RS12015 bc367962111e7e8d0be22ccb89f59e92 413 Pfam PF12704 MacB-like periplasmic core domain 30 206 1.1E-14 T 11-11-2016 IPR025857 MacB-like periplasmic core domain AUP74_RS07405 65929eec99dce2fc72c338c79a3c1fbb 238 Pfam PF02517 CAAX protease self-immunity 80 170 1.6E-14 T 11-11-2016 IPR003675 CAAX amino terminal protease GO:0016020 AUP74_RS03925 e90bebb3bb4e1ef857ff0b87aad159d7 125 Pfam PF04241 Protein of unknown function (DUF423) 19 106 2.4E-28 T 11-11-2016 IPR006696 Protein of unknown function DUF423 AUP74_RS00345 f88b8a8f2827822f93a292e5c40ca41b 210 Pfam PF02517 CAAX protease self-immunity 104 189 2.2E-8 T 11-11-2016 IPR003675 CAAX amino terminal protease GO:0016020 AUP74_RS06980 8430d08c95d0c773f277f4b58c7640f1 410 PRINTS PR00447 Natural resistance-associated macrophage protein signature 293 312 4.5E-11 T 11-11-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 AUP74_RS06980 8430d08c95d0c773f277f4b58c7640f1 410 PRINTS PR00447 Natural resistance-associated macrophage protein signature 197 220 4.5E-11 T 11-11-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 AUP74_RS06980 8430d08c95d0c773f277f4b58c7640f1 410 PRINTS PR00447 Natural resistance-associated macrophage protein signature 148 169 4.5E-11 T 11-11-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 AUP74_RS06980 8430d08c95d0c773f277f4b58c7640f1 410 Pfam PF01566 Natural resistance-associated macrophage protein 28 381 3.8E-94 T 11-11-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 AUP74_RS01190 8f25ebb6a9e5a042d2adafd54574fb5d 303 Pfam PF01758 Sodium Bile acid symporter family 12 193 1.6E-31 T 11-11-2016 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 AUP74_RS13415 d6e7f17d03b5721f8bb8cc471e8e6773 237 Pfam PF04654 Protein of unknown function, DUF599 10 218 3.8E-55 T 11-11-2016 IPR006747 Protein of unknown function DUF599 AUP74_RS11670 798be32c45418ec882048c2c18192426 793 SUPERFAMILY SSF53474 252 358 6.4E-6 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold AUP74_RS07105 025f23b2294b0be781c175af38af7e4f 159 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 12 29 0.0011 T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS07105 025f23b2294b0be781c175af38af7e4f 159 Pfam PF13633 Prokaryotic N-terminal methylation site 8 31 7.5E-6 T 11-11-2016 IPR012902 Prokaryotic N-terminal methylation site AUP74_RS07105 025f23b2294b0be781c175af38af7e4f 159 TIGRFAM TIGR02523 type_IV_pilV: type IV pilus modification protein PilV 8 132 9.2E-25 T 11-11-2016 IPR013362 Pilus modification type IV, PilV AUP74_RS08685 92c824234a2cae28cc120f76f7f2982c 477 Pfam PF04932 O-Antigen ligase 250 391 9.8E-16 T 11-11-2016 IPR007016 O-antigen ligase-related AUP74_RS16530 496142732b78e86516f4d4debd05fd4b 229 Pfam PF09335 SNARE associated Golgi protein 67 183 1.2E-26 T 11-11-2016 IPR032816 SNARE associated Golgi protein AUP74_RS01060 6faf9bcd62d557b658a3bf54b209e9ab 410 Pfam PF13437 HlyD family secretion protein 214 321 3.0E-6 T 11-11-2016 AUP74_RS11075 80dc952085394796abc26f7e4c3966d9 207 Pfam PF01810 LysE type translocator 24 198 2.9E-18 T 11-11-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 AUP74_RS12510 2976256f27484b163f82f4ae6304c006 117 Pfam PF04126 Cyclophilin-like 3 87 3.7E-5 T 11-11-2016 IPR025658 Cyclophilin TM1367-like domain AUP74_RS12510 2976256f27484b163f82f4ae6304c006 117 SUPERFAMILY SSF50891 3 117 2.54E-26 T 11-11-2016 IPR029000 Cyclophilin-like domain AUP74_RS14035 032a5765f298ea7ed50ffa76227abe44 317 Pfam PF14336 Domain of unknown function (DUF4392) 20 288 4.9E-50 T 11-11-2016 IPR025504 Domain of unknown function DUF4392 AUP74_RS08565 943eb7e56855f2e9ca0bbb79575f737b 96 Pfam PF07561 Domain of Unknown Function (DUF1540) 10 44 5.2E-6 T 11-11-2016 IPR011437 Domain of unknown function DUF1540 AUP74_RS08565 943eb7e56855f2e9ca0bbb79575f737b 96 Pfam PF07561 Domain of Unknown Function (DUF1540) 60 83 3.7E-4 T 11-11-2016 IPR011437 Domain of unknown function DUF1540 AUP74_RS11560 d67f339d758fedcd8f877477b42394c7 164 Pfam PF11911 Protein of unknown function (DUF3429) 19 151 8.8E-22 T 11-11-2016 IPR021836 Protein of unknown function DUF3429 AUP74_RS13755 3ef3ed069872f6c7bb33f62317bcaeea 164 Pfam PF12973 ChrR Cupin-like domain 66 138 2.3E-12 T 11-11-2016 IPR025979 ChrR-like cupin domain AUP74_RS13755 3ef3ed069872f6c7bb33f62317bcaeea 164 Gene3D G3DSA:2.60.120.10 77 146 8.9E-12 T 11-11-2016 IPR014710 RmlC-like jelly roll fold AUP74_RS13755 3ef3ed069872f6c7bb33f62317bcaeea 164 SUPERFAMILY SSF51182 52 152 6.86E-14 T 11-11-2016 IPR011051 RmlC-like cupin domain AUP74_RS07665 3c2578d65e529292c80fa72571f3ae3e 198 Pfam PF06930 Protein of unknown function (DUF1282) 8 179 1.8E-31 T 11-11-2016 IPR009698 Protein of unknown function DUF1282 AUP74_RS16830 8200cdf1342d59060d8e211f70118680 646 Pfam PF01435 Peptidase family M48 114 326 1.7E-25 T 11-11-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 AUP74_RS16830 8200cdf1342d59060d8e211f70118680 646 Gene3D G3DSA:3.30.2010.10 104 187 3.9E-24 T 11-11-2016 AUP74_RS13140 a15c1b6b2300743e9cadec4a4733ccb2 748 Gene3D G3DSA:1.50.10.10 356 402 4.1E-7 T 11-11-2016 IPR012341 Six-hairpin glycosidase GO:0003824 AUP74_RS13140 a15c1b6b2300743e9cadec4a4733ccb2 748 Gene3D G3DSA:1.50.10.10 483 654 4.7E-4 T 11-11-2016 IPR012341 Six-hairpin glycosidase GO:0003824 AUP74_RS13140 a15c1b6b2300743e9cadec4a4733ccb2 748 SUPERFAMILY SSF48208 338 658 8.26E-26 T 11-11-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 AUP74_RS15310 86fc80a0a10aa9c4f10524a4cfc4ac0f 248 PRINTS PR00929 AT-hook-like domain signature 236 246 3.7E-5 T 11-11-2016 IPR017956 AT hook, DNA-binding motif GO:0003677 AUP74_RS15310 86fc80a0a10aa9c4f10524a4cfc4ac0f 248 PRINTS PR00929 AT-hook-like domain signature 207 218 3.7E-5 T 11-11-2016 IPR017956 AT hook, DNA-binding motif GO:0003677 AUP74_RS15310 86fc80a0a10aa9c4f10524a4cfc4ac0f 248 PRINTS PR00929 AT-hook-like domain signature 192 202 3.7E-5 T 11-11-2016 IPR017956 AT hook, DNA-binding motif GO:0003677 AUP74_RS01260 c7947e9cf90124cf5597d2679596798d 374 Pfam PF03929 PepSY-associated TM region 6 352 4.4E-52 T 11-11-2016 IPR005625 PepSY-associated TM protein AUP74_RS04790 e7d7cacb437dfe6cf62f2f1aec5dc9e8 343 SUPERFAMILY SSF56112 29 310 1.7E-9 T 11-11-2016 IPR011009 Protein kinase-like domain AUP74_RS12940 79e07545234386560aa01d8bf55f0390 275 Pfam PF03618 Kinase/pyrophosphorylase 9 265 6.4E-74 T 11-11-2016 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 AUP74_RS12940 79e07545234386560aa01d8bf55f0390 275 Hamap MF_01062 Phosphoenolpyruvate synthase regulatory protein [ppsR]. 5 274 68.571 T 11-11-2016 IPR026530 Phosphoenolpyruvate synthase regulatory protein AUP74_RS14760 5bb8834bd9ae3cbaf224d58b9f5460d8 300 Pfam PF00953 Glycosyl transferase family 4 78 217 4.4E-25 T 11-11-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 AUP74_RS12330 f2b2af903c49a3da1c8bae04544ccec3 405 PRINTS PR00812 Bacterial general secretion pathway protein F signature 166 194 2.0E-30 T 11-11-2016 IPR003004 GspF/PilC family AUP74_RS12330 f2b2af903c49a3da1c8bae04544ccec3 405 PRINTS PR00812 Bacterial general secretion pathway protein F signature 67 79 2.0E-30 T 11-11-2016 IPR003004 GspF/PilC family AUP74_RS12330 f2b2af903c49a3da1c8bae04544ccec3 405 PRINTS PR00812 Bacterial general secretion pathway protein F signature 385 404 2.0E-30 T 11-11-2016 IPR003004 GspF/PilC family AUP74_RS12330 f2b2af903c49a3da1c8bae04544ccec3 405 PRINTS PR00812 Bacterial general secretion pathway protein F signature 369 383 2.0E-30 T 11-11-2016 IPR003004 GspF/PilC family AUP74_RS12330 f2b2af903c49a3da1c8bae04544ccec3 405 Pfam PF00482 Type II secretion system (T2SS), protein F 72 194 6.0E-32 T 11-11-2016 IPR018076 Type II secretion system F domain AUP74_RS12330 f2b2af903c49a3da1c8bae04544ccec3 405 Pfam PF00482 Type II secretion system (T2SS), protein F 276 396 3.4E-26 T 11-11-2016 IPR018076 Type II secretion system F domain AUP74_RS12330 f2b2af903c49a3da1c8bae04544ccec3 405 TIGRFAM TIGR02120 GspF: type II secretion system protein F 4 404 8.7E-151 T 11-11-2016 IPR011850 General secretion pathway protein F GO:0008565|GO:0015627|GO:0015628 AUP74_RS15710 d900bc8e25eb1cfe7b9cede7b0ddbe3d 164 Pfam PF07813 LTXXQ motif family protein 43 141 2.9E-11 T 11-11-2016 IPR012899 LTXXQ motif family protein GO:0042597 AUP74_RS10935 54c31bb98924e1a51b64b72e6377fa58 235 Pfam PF13852 Protein of unknown function (DUF4197) 41 231 1.1E-54 T 11-11-2016 IPR025245 Protein of unknown function DUF4197 AUP74_RS15995 fc549edfed46041fd3195c4a3bb3a4b0 115 Pfam PF09842 Predicted membrane protein (DUF2069) 17 112 1.2E-20 T 11-11-2016 IPR018643 Protein of unknown function DUF2069, membrane AUP74_RS04850 a54f3cef9613e1f72a628e79ad10ed76 212 SUPERFAMILY SSF56281 156 197 1.03E-7 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS04850 a54f3cef9613e1f72a628e79ad10ed76 212 SUPERFAMILY SSF56281 4 127 1.03E-7 T 11-11-2016 IPR001279 Metallo-beta-lactamase AUP74_RS02210 ee18b24097b5b65f2dae4eb5a9005fff 221 Pfam PF10707 PhoP regulatory network protein YrbL 2 202 3.1E-48 T 11-11-2016 IPR019647 PhoP regulatory network protein YrbL AUP74_RS03765 711e5e085fbf86c7913d923563bb1da4 269 Pfam PF05235 CHAD domain 33 225 2.2E-25 T 11-11-2016 IPR007899 CHAD domain AUP74_RS03765 711e5e085fbf86c7913d923563bb1da4 269 SMART SM00880 15 260 1.9E-16 T 11-11-2016 IPR007899 CHAD domain AUP74_RS02570 2a6745f41e3f5a0de6f379ac437defd7 138 SUPERFAMILY SSF54593 1 132 4.03E-24 T 11-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AUP74_RS02570 2a6745f41e3f5a0de6f379ac437defd7 138 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 127 5.4E-9 T 11-11-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AUP74_RS02570 2a6745f41e3f5a0de6f379ac437defd7 138 Gene3D G3DSA:3.10.180.10 7 131 4.3E-24 T 11-11-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AUP74_RS05150 bdb2a2442da81b4dce751fe6b1bac4b9 503 Pfam PF13552 Protein of unknown function (DUF4127) 9 489 3.3E-122 T 11-11-2016 IPR025394 Protein of unknown function DUF4127 AUP74_RS16055 d22790e15cfd23cc28c3ac9485127e49 166 Pfam PF02674 Colicin V production protein 5 143 4.6E-39 T 11-11-2016 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 AUP74_RS12425 e848c28317a101d959f065e94550a66f 92 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 28 79 2.5E-18 T 11-11-2016 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 AUP74_RS13190 80e3c05571b981052899e66b71a20ee9 154 Pfam PF10675 Protein of unknown function (DUF2489) 16 149 2.9E-32 T 11-11-2016 IPR019617 Domain of unknown function DUF2489 AUP74_RS14660 641d730addca8b41a521186775bf02e7 269 Pfam PF06405 Red chlorophyll catabolite reductase (RCC reductase) 52 248 2.6E-15 T 11-11-2016 IPR009439 Red chlorophyll catabolite reductase AUP74_RS01030 296cec0eaf0fc6cf036bc2cc134f0690 213 Gene3D G3DSA:3.30.460.10 90 143 1.1E-5 T 11-11-2016 AUP74_RS01030 296cec0eaf0fc6cf036bc2cc134f0690 213 SUPERFAMILY SSF81301 88 140 8.59E-7 T 11-11-2016 AUP74_RS11115 9e37d11290b4a629d53996004501ec66 266 Pfam PF10988 Putative auto-transporter adhesin, head GIN domain 176 263 1.1E-15 T 11-11-2016 IPR021255 Putative auto-transporter adhesin, head GIN domain AUP74_RS11115 9e37d11290b4a629d53996004501ec66 266 Pfam PF10988 Putative auto-transporter adhesin, head GIN domain 40 167 1.1E-20 T 11-11-2016 IPR021255 Putative auto-transporter adhesin, head GIN domain AUP74_RS00315 3b037ceadf8ee3b60e4ca1a111e53d36 280 PIRSF PIRSF028200 4 280 1.8E-58 T 11-11-2016 IPR016875 Uncharacterised conserved protein UCP028200 AUP74_RS14420 b254e2c6b34bd4d277f42bef9eee46d3 320 Gene3D G3DSA:3.20.20.370 10 299 8.7E-56 T 11-11-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 AUP74_RS14420 b254e2c6b34bd4d277f42bef9eee46d3 320 SUPERFAMILY SSF88713 7 297 3.46E-58 T 11-11-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AUP74_RS14420 b254e2c6b34bd4d277f42bef9eee46d3 320 Pfam PF01522 Polysaccharide deacetylase 66 174 2.7E-9 T 11-11-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 AUP74_RS15880 cb1b3fb29863e10177c1d2e1b112741f 427 Pfam PF00999 Sodium/hydrogen exchanger family 17 411 7.7E-56 T 11-11-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 AUP74_RS01095 ffcff9332fd237823baf2a3c381251f2 501 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 162 186 1.0E-15 T 11-11-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS01095 ffcff9332fd237823baf2a3c381251f2 501 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 374 400 1.0E-15 T 11-11-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS01095 ffcff9332fd237823baf2a3c381251f2 501 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 322 341 1.0E-15 T 11-11-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS01095 ffcff9332fd237823baf2a3c381251f2 501 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 132 151 1.0E-15 T 11-11-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS01095 ffcff9332fd237823baf2a3c381251f2 501 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 234 258 1.0E-15 T 11-11-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS01095 ffcff9332fd237823baf2a3c381251f2 501 Pfam PF00361 Proton-conducting membrane transporter 127 418 3.5E-53 T 11-11-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AUP74_RS08750 481a266f9bac79e5d33578d637f44736 453 Pfam PF04932 O-Antigen ligase 239 382 3.7E-8 T 11-11-2016 IPR007016 O-antigen ligase-related AUP74_RS13475 ed6c9bba85405913aaee8a8b70d69f17 154 SUPERFAMILY SSF54637 11 148 2.45E-30 T 11-11-2016 IPR029069 HotDog domain AUP74_RS13475 ed6c9bba85405913aaee8a8b70d69f17 154 Gene3D G3DSA:3.10.129.10 3 153 7.0E-43 T 11-11-2016 IPR029069 HotDog domain AUP74_RS05405 20dc8d1c8c489230a4d42dce69803601 82 Pfam PF04380 Membrane fusogenic activity 10 69 1.1E-11 T 11-11-2016 IPR007475 Membrane fusogenic activity AUP74_RS02540 e3d5ff1caef17092fec6e60c4fd199a1 80 Gene3D G3DSA:1.10.720.30 14 72 3.7E-32 T 11-11-2016 IPR003034 SAP domain AUP74_RS02540 e3d5ff1caef17092fec6e60c4fd199a1 80 Pfam PF09905 Uncharacterized conserved protein (DUF2132) 6 68 2.2E-35 T 11-11-2016 IPR018668 DNA-binding protein VF530-like, bacteria GO:0003677 AUP74_RS09520 a4a777a84493d43eb844b1aeebbfba25 897 Pfam PF07793 Protein of unknown function (DUF1631) 26 868 3.0E-171 T 11-11-2016 IPR012434 Protein of unknown function DUF1631 AUP74_RS12200 775136165a7e58795e67d269b8e0467d 139 Pfam PF02472 Biopolymer transport protein ExbD/TolR 6 135 1.8E-30 T 11-11-2016 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 AUP74_RS03830 1d72561d6ce92ae422036da58bcba1dc 80 Pfam PF11391 Protein of unknown function (DUF2798) 15 73 2.0E-26 T 11-11-2016 IPR021529 Protein of unknown function DUF2798 AUP74_RS03815 7f01ebade73f558b2afd9c534d0becba 124 Pfam PF06155 Protein of unknown function (DUF971) 7 89 2.3E-22 T 11-11-2016 IPR010376 Domain of unknown function DUF971 Reactome: R-HSA-71262 AUP74_RS03880 78612e68d7f378930aa7f11b54671374 118 Pfam PF03788 LrgA family 13 103 2.1E-19 T 11-11-2016 IPR005538 LrgA/CidA family GO:0016021 AUP74_RS05655 f804d7a8265762375263a6d95fb3af4a 456 Pfam PF04375 HemX, putative uroporphyrinogen-III C-methyltransferase 79 441 1.9E-55 T 11-11-2016 IPR007470 Putative uroporphyrinogen-III C-methyltransferase HemX AUP74_RS13195 841be9d2e67947d81e373662a2963d06 309 Pfam PF03547 Membrane transport protein 13 146 1.7E-8 T 11-11-2016 IPR004776 Membrane transport protein GO:0016021|GO:0055085 AUP74_RS13195 841be9d2e67947d81e373662a2963d06 309 Pfam PF03547 Membrane transport protein 168 300 1.6E-12 T 11-11-2016 IPR004776 Membrane transport protein GO:0016021|GO:0055085 AUP74_RS12745 24187fee11ab0e76b2eca98899d28b64 197 Pfam PF04214 Protein of unknown function, DUF 81 149 1.6E-25 T 11-11-2016 IPR007332 Protein of unknown function DUF411 AUP74_RS06245 e44fa5daa0240aa95be3726c97920b34 373 Pfam PF12412 Protein of unknown function (DUF3667) 35 78 2.8E-14 T 11-11-2016 IPR022134 Protein of unknown function DUF3667 AUP74_RS03595 abf9b5ec82e501bb9d61909cb6ea3b39 126 Pfam PF11456 Protein of unknown function (DUF3019) 26 125 6.0E-17 T 11-11-2016 IPR021559 Protein of unknown function DUF3019 AUP74_RS12420 815c5cc34b6d136a80f155f5c35cfb5b 162 Pfam PF01899 Na+/H+ ion antiporter subunit 14 158 6.9E-28 T 11-11-2016 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 AUP74_RS07805 3af68b070bc525a3d77cd2b5f6678a8a 86 Pfam PF11246 Base plate wedge protein 53 22 73 4.6E-5 T 11-11-2016 IPR022607 Baseplate wedge protein gp53, bacteriophage T4 AUP74_RS04175 703db64fdd592ab296854a0a3607b4cc 159 Pfam PF14085 Domain of unknown function (DUF4265) 22 125 1.3E-20 T 11-11-2016 IPR025361 Protein of unknown function DUF4265 AUP74_RS09885 91eb4e5d45865aa496102a8453de959c 78 Pfam PF06906 Protein of unknown function (DUF1272) 1 55 7.2E-22 T 11-11-2016 IPR010696 Protein of unknown function DUF1272 AUP74_RS08125 e85b7109b02d8d95a16dd428990eec20 259 Pfam PF01618 MotA/TolQ/ExbB proton channel family 74 197 8.7E-23 T 11-11-2016 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 AUP74_RS00120 d3cb1f1b23c69237e82f2c22448aa91c 669 Pfam PF01757 Acyltransferase family 8 332 1.3E-29 T 11-11-2016 IPR002656 Acyltransferase 3 GO:0016747 AUP74_RS05225 1bde0cb97fe65f38c970a3ffcd2fa8d4 380 Gene3D G3DSA:3.40.50.2300 4 138 1.8E-8 T 11-11-2016 AUP74_RS05225 1bde0cb97fe65f38c970a3ffcd2fa8d4 380 SUPERFAMILY SSF52172 4 174 5.86E-10 T 11-11-2016 IPR011006 CheY-like superfamily AUP74_RS14885 932fd666d00ec970e07d38a41d42d01b 297 Pfam PF01963 TraB family 30 295 2.2E-66 T 11-11-2016 IPR002816 Pheromone shutdown, TraB AUP74_RS12315 0cff64d4c3d7294c25dae010853c7d56 222 Pfam PF11356 Type II secretion system protein C 24 162 7.8E-24 T 11-11-2016 IPR024961 Type II secretion system protein C, N-terminal AUP74_RS14785 596ff701fe8cf9efe87a514d11789db8 88 Pfam PF06305 Protein of unknown function (DUF1049) 16 78 3.8E-8 T 11-11-2016 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 AUP74_RS15755 3b8db7f1b1295d21bb558d4126c69441 238 PIRSF PIRSF028137 7 238 5.5E-78 T 11-11-2016 IPR016870 Uncharacterised conserved protein UCP028137, membrane AUP74_RS15430 2cfab1666132ba3664edf695e5bb24f2 126 Pfam PF07254 Membrane-bound toxin component of toxin-antitoxin system 5 122 1.2E-7 T 11-11-2016 IPR009883 Toxin CptA AUP74_RS16360 965facc73db2183900e7cbbda5e2b7a8 128 Pfam PF11042 Protein of unknown function (DUF2750) 18 121 3.5E-25 T 11-11-2016 IPR021284 Protein of unknown function DUF2750 AUP74_RS13720 8e0df7164af5723b061e0d153c1a6ae1 171 Pfam PF11086 Protein of unknown function (DUF2878) 5 155 4.3E-30 T 11-11-2016 IPR021306 Protein of unknown function DUF2878 AUP74_RS08485 6c07673bd49661dff103ed04cfb06e92 243 Pfam PF07277 SapC 7 232 4.2E-74 T 11-11-2016 IPR010836 SapC AUP74_RS12040 5784f7642e0d3a75243d3988bb09b1d0 175 Pfam PF09835 Uncharacterized protein conserved in bacteria (DUF2062) 22 164 3.2E-50 T 11-11-2016 IPR018639 Domain of unknown function DUF2062 AUP74_RS05265 d120f70b9cfdd59b4abeacaec33a61fb 786 Pfam PF02687 FtsX-like permease family 230 340 2.3E-9 T 11-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 AUP74_RS15795 771ea6748e9ad543da5be01e0cafde83 562 TIGRFAM TIGR03505 FimV_core: FimV N-terminal domain 130 186 4.0E-15 T 11-11-2016 IPR020012 Motility protein FimV, N-terminal AUP74_RS01390 cb992b83f75a50824607f67596d1e200 462 Pfam PF00474 Sodium:solute symporter family 20 398 4.9E-48 T 11-11-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 AUP74_RS00860 7528042893072a50366f99a9d634d735 374 Pfam PF01594 Domain of unknown function DUF20 19 345 1.1E-70 T 11-11-2016 IPR002549 Transmembrane protein TqsA-like AUP74_RS13200 21c59b48f83bb5dd8731038647ff369d 460 Pfam PF02646 RmuC family 135 430 4.9E-104 T 11-11-2016 IPR003798 DNA recombination RmuC AUP74_RS08880 b29e87f2ce896aea99be574687e56439 108 Pfam PF10082 Putative beta-barrel porin 2 31 104 1.9E-7 T 11-11-2016 IPR018759 Putative beta-barrel porin 2 AUP74_RS05285 86c5fbdf84cd3c6400c357af6187e85d 251 Pfam PF14243 Domain of unknown function (DUF4343) 112 243 6.8E-26 T 11-11-2016 IPR025643 Protein of unknown function DUF4343 AUP74_RS16035 f0e004691fbde4e71b485fd91a6c40c7 319 Pfam PF01882 Protein of unknown function DUF58 210 287 1.1E-14 T 11-11-2016 IPR002881 Domain of unknown function DUF58 AUP74_RS02040 b465e9fb37305703671215bfe2fda8df 236 Pfam PF12261 Thermostable hemolysin 34 199 6.0E-55 T 11-11-2016 IPR022050 Thermostable hemolysin AUP74_RS15575 4ef8af6d7930046637870a2206ec6d8b 266 Pfam PF01578 Cytochrome C assembly protein 43 262 1.5E-28 T 11-11-2016 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 AUP74_RS02895 68492eb9114affb647fa3d8460e3691b 65 Pfam PF14255 Cysteine-rich CPXCG 10 57 2.5E-21 T 11-11-2016 IPR025990 Cysteine-rich CPXCG protein AUP74_RS02895 68492eb9114affb647fa3d8460e3691b 65 PIRSF PIRSF037225 3 64 1.2E-20 T 11-11-2016 IPR017143 Uncharacterised conserved protein UCP037225 AUP74_RS11535 0c2e8ece7edaeac961885e0079f0e0ba 146 Gene3D G3DSA:1.20.1260.10 7 111 7.2E-5 T 11-11-2016 IPR012347 Ferritin-related AUP74_RS13010 5cf0207a3ce856f190062d6bd76482d3 173 Pfam PF10003 Integral membrane protein (DUF2244) 17 157 6.1E-30 T 11-11-2016 IPR019253 Protein of unknown function DUF2244, transmembrane AUP74_RS08840 8c437b5ef492135471ac1bcad586b346 408 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 295 382 3.6E-14 T 11-11-2016 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain AUP74_RS00730 7d0a33b72c8bef64496d63ffcd213107 392 Pfam PF06804 NlpB/DapX lipoprotein 35 308 5.9E-21 T 11-11-2016 IPR010653 NlpB/DapX lipoprotein AUP74_RS15010 b96648a536a3fc4ff691f394f6434f8b 239 Pfam PF04402 Protein of unknown function (DUF541) 30 235 1.6E-46 T 11-11-2016 IPR007497 Protein of unknown function DUF541 AUP74_RS14970 64018e22d158504794be21dfdf2faf6e 478 Pfam PF03606 C4-dicarboxylate anaerobic carrier 1 473 4.9E-120 T 11-11-2016 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 AUP74_RS02755 7b2301c025095ec4fbad81d46e3fd630 198 Pfam PF03729 Short repeat of unknown function (DUF308) 26 96 2.0E-15 T 11-11-2016 IPR005325 Protein of unknown function DUF308, membrane AUP74_RS02755 7b2301c025095ec4fbad81d46e3fd630 198 Pfam PF03729 Short repeat of unknown function (DUF308) 141 189 1.2E-7 T 11-11-2016 IPR005325 Protein of unknown function DUF308, membrane AUP74_RS02755 7b2301c025095ec4fbad81d46e3fd630 198 Pfam PF03729 Short repeat of unknown function (DUF308) 83 154 3.4E-13 T 11-11-2016 IPR005325 Protein of unknown function DUF308, membrane AUP74_RS07540 8fbe139e73ae69aa9ffd3f3da0d926f4 140 Pfam PF02472 Biopolymer transport protein ExbD/TolR 11 128 2.7E-26 T 11-11-2016 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 AUP74_RS00240 057c822ed8aadeae8fa4621fb9ad7a5b 240 Pfam PF07277 SapC 12 231 7.9E-71 T 11-11-2016 IPR010836 SapC AUP74_RS13915 42d92b7ed10df69b4a669024261f5cb3 524 Pfam PF00474 Sodium:solute symporter family 38 445 3.8E-29 T 11-11-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 AUP74_RS08980 8d98b978fe43e72d665f0d22cb941ee1 368 Pfam PF07786 Protein of unknown function (DUF1624) 32 203 1.2E-9 T 11-11-2016 IPR012429 Protein of unknown function DUF1624 KEGG: 00531+2.3.1.78|Reactome: R-HSA-2024096|Reactome: R-HSA-2206291