locus-tag	class	description
FIU95_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FIU95_RS00010	COG0592	DNA-directed DNA polymerase activity
FIU95_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FIU95_RS00035	COG0175	sulfate reduction
FIU95_RS00060	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FIU95_RS00065	COG1404	Belongs to the peptidase S8 family
FIU95_RS00070	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FIU95_RS00075	COG0751	glycine-tRNA ligase activity
FIU95_RS00080	COG0752	glycyl-tRNA synthetase alpha subunit
FIU95_RS00095	COG1136	(ABC) transporter
FIU95_RS00095	COG0577	efflux transmembrane transporter activity
FIU95_RS00100	COG1136	(ABC) transporter
FIU95_RS00110	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FIU95_RS00115	COG0569	domain protein
FIU95_RS00125	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FIU95_RS00130	COG0242	peptide deformylase activity
FIU95_RS00140	COG0758	DNA mediated transformation
FIU95_RS00145	COG0753	catalase activity
FIU95_RS00155	COG0009	L-threonylcarbamoyladenylate synthase
FIU95_RS00160	COG0408	coproporphyrinogen oxidase activity
FIU95_RS00170	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FIU95_RS00190	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FIU95_RS00195	COG0339	signal peptide processing
FIU95_RS00210	COG0534	Mate efflux family protein
FIU95_RS00220	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FIU95_RS00225	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FIU95_RS00250	COG1612	heme a metabolic process
FIU95_RS00255	COG0109	protoheme IX farnesyltransferase activity
FIU95_RS00280	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FIU95_RS00285	COG1121	(ABC) transporter
FIU95_RS00310	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FIU95_RS00320	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FIU95_RS00340	COG4574	serine-type endopeptidase inhibitor activity
FIU95_RS00365	COG2234	aminopeptidase activity
FIU95_RS00375	COG0583	DNA-binding transcription factor activity
FIU95_RS00385	COG3040	lipid binding
FIU95_RS00410	COG0714	Associated with various cellular activities
FIU95_RS00455	COG2268	Band 7 protein
FIU95_RS00470	COG0789	Transcriptional regulator
FIU95_RS00480	COG0530	calcium, potassium:sodium antiporter activity
FIU95_RS00495	COG0346	lactoylglutathione lyase activity
FIU95_RS00505	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIU95_RS00510	COG3177	Filamentation induced by cAMP protein fic
FIU95_RS00520	COG0730	response to heat
FIU95_RS00530	COG4650	regulator
FIU95_RS00535	COG1690	Belongs to the RtcB family
FIU95_RS00545	COG0430	RNA-3'-phosphate cyclase activity
FIU95_RS00580	COG3850	Histidine kinase
FIU95_RS00625	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FIU95_RS00650	COG0515	serine threonine protein kinase
FIU95_RS00650	COG2815	serine threonine protein kinase
FIU95_RS00665	COG0746	molybdenum cofactor guanylyltransferase activity
FIU95_RS00670	COG0521	Mo-molybdopterin cofactor biosynthetic process
FIU95_RS00675	COG0315	cyclic pyranopterin monophosphate synthase activity
FIU95_RS00680	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FIU95_RS00685	COG0314	molybdopterin synthase activity
FIU95_RS00710	COG2197	response regulator
FIU95_RS00715	COG0303	'Molybdopterin
FIU95_RS00730	COG0210	DNA helicase
FIU95_RS00740	COG1671	Belongs to the UPF0178 family
FIU95_RS00790	COG0606	chelatase, subunit chli
FIU95_RS00795	COG2960	long-chain fatty acid transporting porin activity
FIU95_RS00810	COG0004	ammonium transporteR
FIU95_RS00815	COG0347	Belongs to the P(II) protein family
FIU95_RS00830	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FIU95_RS00845	COG1965	Belongs to the frataxin family
FIU95_RS00850	COG0165	Argininosuccinate lyase
FIU95_RS00855	COG0745	RESPONSE REGULATOR receiver
FIU95_RS00855	COG2972	Histidine kinase
FIU95_RS00900	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FIU95_RS00905	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FIU95_RS00910	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FIU95_RS00910	COG2813	Specifically methylates the guanine in position
FIU95_RS00925	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FIU95_RS00940	COG0724	RNA recognition motif
FIU95_RS00945	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FIU95_RS00995	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FIU95_RS01000	COG1678	Uncharacterized ACR, COG1678
FIU95_RS01030	COG0840	transmembrane signaling receptor activity
FIU95_RS01035	COG0784	Response regulator, receiver
FIU95_RS01035	COG0643	Histidine kinase
FIU95_RS01035	COG2198	Histidine kinase
FIU95_RS01075	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FIU95_RS01080	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FIU95_RS01085	COG0069	glutamate synthase activity
FIU95_RS01085	COG0067	glutamate synthase
FIU95_RS01085	COG0070	glutamate synthase
FIU95_RS01090	COG0493	'glutamate synthase
FIU95_RS01095	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FIU95_RS01100	COG3437	response regulator, receiver
FIU95_RS01105	COG0688	phosphatidylethanolamine metabolic process
FIU95_RS01115	COG1162	GTPase activity
FIU95_RS01120	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FIU95_RS01130	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FIU95_RS01130	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FIU95_RS01135	COG0802	atpase or kinase
FIU95_RS01145	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FIU95_RS01150	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FIU95_RS01155	COG1923	regulation of RNA biosynthetic process
FIU95_RS01160	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FIU95_RS01165	COG0330	HflC and HflK could
FIU95_RS01170	COG0330	HflC and HflK could
FIU95_RS01175	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FIU95_RS01180	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FIU95_RS01185	COG1272	protein, Hemolysin III
FIU95_RS01190	COG2951	lytic endotransglycosylase activity
FIU95_RS01205	COG0631	protein serine/threonine phosphatase activity
FIU95_RS01330	COG2815	serine threonine protein kinase
FIU95_RS01330	COG0515	serine threonine protein kinase
FIU95_RS01350	COG0557	exoribonuclease II activity
FIU95_RS01355	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FIU95_RS01360	COG1595	DNA-templated transcription, initiation
FIU95_RS01390	COG0360	Binds together with S18 to 16S ribosomal RNA
FIU95_RS01395	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FIU95_RS01405	COG0359	binds to the 23S rRNA
FIU95_RS01410	COG0305	Participates in initiation and elongation during chromosome replication
FIU95_RS01415	COG3214	Protein conserved in bacteria
FIU95_RS01425	COG0010	Belongs to the arginase family
FIU95_RS01440	COG1166	arginine decarboxylase activity
FIU95_RS01450	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FIU95_RS01455	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FIU95_RS01465	COG1683	Conserved Protein
FIU95_RS01470	COG0662	Cupin 2, conserved barrel domain protein
FIU95_RS01475	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIU95_RS01495	COG0753	catalase activity
FIU95_RS01505	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FIU95_RS01510	COG1045	serine acetyltransferase
FIU95_RS01525	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FIU95_RS01540	COG1509	lysine 2,3-aminomutase activity
FIU95_RS01560	COG0560	Phosphoserine phosphatase
FIU95_RS01560	COG3830	Belongs to the UPF0237 family
FIU95_RS01570	COG0789	Transcriptional regulator
FIU95_RS01575	COG1960	acyl-CoA dehydrogenase activity
FIU95_RS01580	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FIU95_RS01585	COG1024	Enoyl-CoA hydratase
FIU95_RS01590	COG4770	biotin carboxylase activity
FIU95_RS01610	COG2132	Multicopper oxidase
FIU95_RS01615	COG3738	Protein conserved in bacteria
FIU95_RS01645	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FIU95_RS01660	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FIU95_RS01680	COG1040	competence protein
FIU95_RS01685	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FIU95_RS01690	COG0156	8-amino-7-oxononanoate synthase activity
FIU95_RS01695	COG1073	alpha beta
FIU95_RS01695	COG2226	methyltransferase
FIU95_RS01710	COG1960	acyl-CoA dehydrogenase activity
FIU95_RS01725	COG0745	RESPONSE REGULATOR receiver
FIU95_RS01730	COG2205	protein histidine kinase activity
FIU95_RS01735	COG4452	Inner membrane protein CreD
FIU95_RS01745	COG3275	phosphorelay sensor kinase activity
FIU95_RS01770	COG3264	Mechanosensitive ion channel
FIU95_RS01770	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FIU95_RS01795	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FIU95_RS01820	COG2207	Transcriptional regulator
FIU95_RS01830	COG0604	alcohol dehydrogenase
FIU95_RS01855	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FIU95_RS01860	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FIU95_RS01865	COG0358	DNA primase activity
FIU95_RS01870	COG1610	YqeY-like protein
FIU95_RS01875	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FIU95_RS01880	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FIU95_RS01885	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FIU95_RS01890	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FIU95_RS01910	COG2972	Histidine kinase
FIU95_RS01920	COG1028	Short-chain dehydrogenase reductase Sdr
FIU95_RS01925	COG0617	tRNA 3'-terminal CCA addition
FIU95_RS01935	COG2719	SpoVR family
FIU95_RS01940	COG2718	Belongs to the UPF0229 family
FIU95_RS01945	COG2766	serine protein kinase
FIU95_RS01950	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FIU95_RS01960	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FIU95_RS01965	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FIU95_RS01970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FIU95_RS01975	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FIU95_RS01980	COG3178	'Phosphotransferase
FIU95_RS01985	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FIU95_RS01995	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FIU95_RS02005	COG0512	Glutamine amidotransferase of anthranilate synthase
FIU95_RS02010	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FIU95_RS02015	COG0134	indole-3-glycerol-phosphate synthase activity
FIU95_RS02025	COG1765	OsmC-like protein
FIU95_RS02030	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
FIU95_RS02035	COG0151	Belongs to the GarS family
FIU95_RS02040	COG0138	bifunctional purine biosynthesis protein purh
FIU95_RS02045	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FIU95_RS02060	COG2264	protein methyltransferase activity
FIU95_RS02070	COG0511	ligase activity, forming carbon-carbon bonds
FIU95_RS02075	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FIU95_RS02100	COG5002	protein histidine kinase activity
FIU95_RS02100	COG5001	Diguanylate cyclase
FIU95_RS02105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU95_RS02110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FIU95_RS02125	COG3135	benzoate transporter
FIU95_RS02130	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FIU95_RS02140	COG1981	membrane
FIU95_RS02150	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FIU95_RS02165	COG0316	Belongs to the HesB IscA family
FIU95_RS02170	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FIU95_RS02175	COG0739	heme binding
FIU95_RS02220	COG1131	(ABC) transporter
FIU95_RS02230	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FIU95_RS02235	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FIU95_RS02235	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FIU95_RS02240	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FIU95_RS02270	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FIU95_RS02290	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FIU95_RS02295	COG0081	regulation of translation
FIU95_RS02300	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FIU95_RS02305	COG0222	ribosome binding
FIU95_RS02310	COG0085	RNA polymerase activity
FIU95_RS02315	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FIU95_RS02320	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FIU95_RS02325	COG0049	tRNA binding
FIU95_RS02330	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FIU95_RS02335	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FIU95_RS02345	COG0051	transcription antitermination factor activity, RNA binding
FIU95_RS02350	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FIU95_RS02355	COG0088	Forms part of the polypeptide exit tunnel
FIU95_RS02360	COG0089	rRNA binding
FIU95_RS02365	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FIU95_RS02370	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FIU95_RS02375	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FIU95_RS02380	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FIU95_RS02385	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FIU95_RS02390	COG0255	Belongs to the universal ribosomal protein uL29 family
FIU95_RS02395	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FIU95_RS02400	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FIU95_RS02405	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FIU95_RS02410	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FIU95_RS02415	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FIU95_RS02420	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FIU95_RS02425	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FIU95_RS02430	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FIU95_RS02435	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FIU95_RS02440	COG1841	ribosomal large subunit assembly
FIU95_RS02445	COG0200	Binds to the 23S rRNA
FIU95_RS02455	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FIU95_RS02460	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FIU95_RS02465	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FIU95_RS02470	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FIU95_RS02475	COG0202	RNA polymerase activity
FIU95_RS02480	COG0203	ribosomal protein L17
FIU95_RS02485	COG3139	Protein of unknown function (DUF1315)
FIU95_RS02500	COG1984	allophanate hydrolase subunit 2
FIU95_RS02505	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FIU95_RS02530	COG2814	Major facilitator Superfamily
FIU95_RS02550	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FIU95_RS02560	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FIU95_RS02565	COG0142	geranyltranstransferase activity
FIU95_RS02570	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FIU95_RS02575	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FIU95_RS02580	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FIU95_RS02585	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FIU95_RS02590	COG0268	Binds directly to 16S ribosomal RNA
FIU95_RS02595	COG2205	protein histidine kinase activity
FIU95_RS02600	COG0745	RESPONSE REGULATOR receiver
FIU95_RS02605	COG2885	chlorophyll binding
FIU95_RS02610	COG0728	peptidoglycan biosynthetic process
FIU95_RS02615	COG0196	riboflavin kinase activity
FIU95_RS02620	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FIU95_RS02630	COG1047	Peptidyl-prolyl cis-trans
FIU95_RS02635	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FIU95_RS02685	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIU95_RS02685	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FIU95_RS02700	COG1496	oxidoreductase activity
FIU95_RS02710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU95_RS02715	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU95_RS02740	COG0028	Belongs to the TPP enzyme family
FIU95_RS02745	COG0440	acetolactate synthase activity
FIU95_RS02750	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FIU95_RS02755	COG1183	phosphatidylcholine synthase activity
FIU95_RS02805	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FIU95_RS02830	COG5532	Uncharacterized conserved protein (DUF2303)
FIU95_RS02925	COG4626	Terminase
FIU95_RS02925	COG1802	Transcriptional regulator
FIU95_RS02930	COG4695	Portal protein
FIU95_RS03030	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FIU95_RS03060	COG0745	RESPONSE REGULATOR receiver
FIU95_RS03065	COG2205	protein histidine kinase activity
FIU95_RS03090	COG0534	Mate efflux family protein
FIU95_RS03105	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FIU95_RS03110	COG1846	Transcriptional regulator
FIU95_RS03115	COG0386	Belongs to the glutathione peroxidase family
FIU95_RS03120	COG0672	)-iron permease
FIU95_RS03130	COG0477	Major facilitator Superfamily
FIU95_RS03145	COG3590	peptidase
FIU95_RS03155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FIU95_RS03160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU95_RS03165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU95_RS03170	COG0572	uridine kinase
FIU95_RS03185	COG1803	Methylglyoxal synthase
FIU95_RS03190	COG0848	biopolymer transport protein
FIU95_RS03195	COG3483	tryptophan 2,3-dioxygenase activity
FIU95_RS03205	COG2235	arginine
FIU95_RS03210	COG1024	Enoyl-CoA hydratase
FIU95_RS03215	COG0584	glycerophosphoryl diester phosphodiesterase
FIU95_RS03225	COG4783	chaperone-mediated protein folding
FIU95_RS03290	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FIU95_RS03325	COG4660	Part of a membrane complex involved in electron transport
FIU95_RS03335	COG4658	electron transport chain
FIU95_RS03345	COG2878	Part of a membrane complex involved in electron transport
FIU95_RS03350	COG4657	Part of a membrane complex involved in electron transport
FIU95_RS03355	COG0625	glutathione transferase activity
FIU95_RS03375	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FIU95_RS03385	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FIU95_RS03385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FIU95_RS03390	COG0489	protein tyrosine kinase activity
FIU95_RS03400	COG1054	Belongs to the UPF0176 family
FIU95_RS03425	COG0247	lactate metabolic process
FIU95_RS03425	COG0277	FAD linked oxidase domain protein
FIU95_RS03430	COG3272	Protein of unknown function (DUF1722)
FIU95_RS03435	COG0789	Transcriptional regulator
FIU95_RS03440	COG0415	Belongs to the DNA photolyase family
FIU95_RS03455	COG0668	transmembrane transport
FIU95_RS03475	COG0793	Belongs to the peptidase S41A family
FIU95_RS03485	COG1522	sequence-specific DNA binding
FIU95_RS03515	COG0442	prolyl-tRNA aminoacylation
FIU95_RS03530	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FIU95_RS03540	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FIU95_RS03545	COG0632	four-way junction helicase activity
FIU95_RS03550	COG2255	four-way junction helicase activity
FIU95_RS03555	COG0824	Thioesterase
FIU95_RS03575	COG0823	Involved in the tonB-independent uptake of proteins
FIU95_RS03580	COG2885	chlorophyll binding
FIU95_RS03590	COG0602	queuosine metabolic process
FIU95_RS03595	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FIU95_RS03630	COG0579	oxidoreductase
FIU95_RS03635	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FIU95_RS03640	COG4783	chaperone-mediated protein folding
FIU95_RS03655	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FIU95_RS03685	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIU95_RS03720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU95_RS03725	COG4977	sequence-specific DNA binding
FIU95_RS03745	COG2204	response regulator
FIU95_RS03755	COG0577	efflux transmembrane transporter activity
FIU95_RS03755	COG1136	(ABC) transporter
FIU95_RS03765	COG1136	(ABC) transporter
FIU95_RS03770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU95_RS03775	COG0659	secondary active sulfate transmembrane transporter activity
FIU95_RS03780	COG0589	response to stress
FIU95_RS03790	COG1522	sequence-specific DNA binding
FIU95_RS03795	COG3647	Membrane
FIU95_RS03810	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FIU95_RS03815	COG0667	Aldo Keto reductase
FIU95_RS03825	COG1560	Kdo2-lipid A biosynthetic process
FIU95_RS03835	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FIU95_RS03840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIU95_RS03845	COG0730	response to heat
FIU95_RS03850	COG0730	response to heat
FIU95_RS03855	COG3104	oligopeptide transport
FIU95_RS03865	COG4771	TonB-dependent receptor
FIU95_RS03870	COG4771	TonB-dependent receptor
FIU95_RS03875	COG0457	Tetratricopeptide repeat
FIU95_RS03910	COG1595	DNA-templated transcription, initiation
FIU95_RS03915	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FIU95_RS03920	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FIU95_RS03925	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FIU95_RS03940	COG2983	Belongs to the UPF0260 family
FIU95_RS03955	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FIU95_RS03965	COG3104	oligopeptide transport
FIU95_RS03970	COG1643	Atp-dependent helicase
FIU95_RS03980	COG3220	belongs to the UPF0276 family
FIU95_RS03995	COG2204	response regulator
FIU95_RS04010	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FIU95_RS04015	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FIU95_RS04070	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FIU95_RS04185	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FIU95_RS04195	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FIU95_RS04200	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FIU95_RS04205	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FIU95_RS04215	COG0438	transferase activity, transferring glycosyl groups
FIU95_RS04215	COG1216	Glycosyl transferase, family 2
FIU95_RS04255	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FIU95_RS04260	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FIU95_RS04285	COG0110	maltose O-acetyltransferase activity
FIU95_RS04300	COG1442	glycosyl transferase family 8
FIU95_RS04300	COG1216	Glycosyl transferase, family 2
FIU95_RS04310	COG0438	transferase activity, transferring glycosyl groups
FIU95_RS04310	COG1216	Glycosyl transferase, family 2
FIU95_RS04315	COG0471	metal ion transport
FIU95_RS04315	COG3273	potassium ion transport
FIU95_RS04355	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FIU95_RS04360	COG0416	fatty acid biosynthetic process
FIU95_RS04375	COG0006	proline dipeptidase activity
FIU95_RS04380	COG0788	formyltetrahydrofolate deformylase activity
FIU95_RS04390	COG1917	Cupin 2, conserved barrel domain protein
FIU95_RS04390	COG2207	Transcriptional regulator
FIU95_RS04415	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FIU95_RS04415	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FIU95_RS04430	COG0018	arginyl-trna synthetase
FIU95_RS04435	COG2925	Exonuclease
FIU95_RS04440	COG0540	Belongs to the ATCase OTCase family
FIU95_RS04455	COG0166	Belongs to the GPI family
FIU95_RS04470	COG1757	Na H antiporter
FIU95_RS04480	COG1199	ATP-dependent helicase activity
FIU95_RS04485	COG3098	single-species biofilm formation
FIU95_RS04555	COG0443	Heat shock 70 kDa protein
FIU95_RS04570	COG0105	UTP biosynthetic process
FIU95_RS04575	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FIU95_RS04580	COG1858	cytochrome C peroxidase
FIU95_RS04600	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FIU95_RS04605	COG0124	histidyl-tRNA synthetase
FIU95_RS04610	COG2976	Protein conserved in bacteria
FIU95_RS04620	COG1160	GTP binding
FIU95_RS04635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIU95_RS04645	COG3791	Glutathione-dependent formaldehyde-activating
FIU95_RS04660	COG0438	transferase activity, transferring glycosyl groups
FIU95_RS04670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIU95_RS04680	COG1794	racemase activity, acting on amino acids and derivatives
FIU95_RS04695	COG1007	ATP synthesis coupled electron transport
FIU95_RS04705	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FIU95_RS04710	COG0713	ATP synthesis coupled electron transport
FIU95_RS04715	COG0839	Belongs to the complex I subunit 6 family
FIU95_RS04720	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FIU95_RS04725	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FIU95_RS04730	COG1034	ATP synthesis coupled electron transport
FIU95_RS04735	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FIU95_RS04740	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FIU95_RS04745	COG0649	NAD binding
FIU95_RS04745	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FIU95_RS04750	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FIU95_RS04755	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FIU95_RS04780	COG4628	conserved protein (DUF2132)
FIU95_RS04820	COG4628	conserved protein (DUF2132)
FIU95_RS04900	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FIU95_RS04925	COG0525	valine-tRNA ligase activity
FIU95_RS04940	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FIU95_RS04945	COG0795	lipopolysaccharide-transporting ATPase activity
FIU95_RS04950	COG0795	lipopolysaccharide-transporting ATPase activity
FIU95_RS04975	COG2226	methyltransferase
FIU95_RS04980	COG0590	tRNA wobble adenosine to inosine editing
FIU95_RS04995	COG2814	Major facilitator Superfamily
FIU95_RS05010	COG0583	DNA-binding transcription factor activity
FIU95_RS05015	COG0590	tRNA wobble adenosine to inosine editing
FIU95_RS05030	COG0583	DNA-binding transcription factor activity
FIU95_RS05035	COG1279	arginine transmembrane transporter activity
FIU95_RS05050	COG2226	methyltransferase
FIU95_RS05055	COG3621	Patatin-like phospholipase
FIU95_RS05060	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FIU95_RS05065	COG2267	carboxylic ester hydrolase activity
FIU95_RS05165	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FIU95_RS05170	COG0343	queuine tRNA-ribosyltransferase activity
FIU95_RS05180	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FIU95_RS05195	COG0418	dihydroorotase activity
FIU95_RS05200	COG0137	argininosuccinate synthase activity
FIU95_RS05205	COG3278	Belongs to the heme-copper respiratory oxidase family
FIU95_RS05220	COG2010	Cytochrome c
FIU95_RS05235	COG2217	Heavy metal translocating P-type atpase
FIU95_RS05260	COG3023	N-Acetylmuramoyl-L-alanine amidase
FIU95_RS05265	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FIU95_RS05270	COG1012	belongs to the aldehyde dehydrogenase family
FIU95_RS05275	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FIU95_RS05280	COG1881	PFAM PEBP family protein
FIU95_RS05290	COG2814	Major facilitator Superfamily
FIU95_RS05295	COG3695	enzyme binding
FIU95_RS05305	COG1028	Short-chain dehydrogenase reductase Sdr
FIU95_RS05315	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FIU95_RS05325	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FIU95_RS05330	COG0459	protein refolding
FIU95_RS05345	COG0745	RESPONSE REGULATOR receiver
FIU95_RS05350	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FIU95_RS05375	COG1840	ABC-type Fe3 transport system, periplasmic component
FIU95_RS05380	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FIU95_RS05385	COG3842	ATPase activity
FIU95_RS05405	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FIU95_RS05415	COG3344	reverse transcriptase
FIU95_RS05425	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FIU95_RS05435	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIU95_RS05440	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FIU95_RS05445	COG4181	ATPase activity
FIU95_RS05455	COG0037	tRNA processing
FIU95_RS05470	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FIU95_RS05485	COG0686	Belongs to the AlaDH PNT family
FIU95_RS05520	COG2067	long-chain fatty acid transport protein
FIU95_RS05530	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FIU95_RS05535	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FIU95_RS05545	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FIU95_RS05550	COG0589	response to stress
FIU95_RS05575	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FIU95_RS05575	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FIU95_RS05585	COG2154	pterin-4-alpha-carbinolamine dehydratase
FIU95_RS05645	COG0189	ligase activity
FIU95_RS05675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU95_RS05690	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FIU95_RS05690	COG3323	Protein of unknown function (DUF1653)
FIU95_RS05695	COG3118	belongs to the thioredoxin family
FIU95_RS05700	COG2315	Protein conserved in bacteria
FIU95_RS05715	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FIU95_RS05725	COG1280	lysine exporter protein (LysE YggA)
FIU95_RS05760	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FIU95_RS05765	COG2137	regulation of response to DNA damage stimulus
FIU95_RS05770	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FIU95_RS05775	COG3588	fructose-bisphosphate aldolase
FIU95_RS05785	COG2835	tetraacyldisaccharide 4'-kinase activity
FIU95_RS05790	COG0537	adenosine 5'-monophosphoramidase activity
FIU95_RS05795	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FIU95_RS05800	COG0527	aspartate kinase activity
FIU95_RS05805	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FIU95_RS05860	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FIU95_RS05875	COG2022	thiamine diphosphate biosynthetic process
FIU95_RS05885	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FIU95_RS05890	COG0783	Belongs to the Dps family
FIU95_RS05900	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIU95_RS05910	COG0729	surface antigen
FIU95_RS05950	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FIU95_RS05955	COG4771	TonB-dependent receptor
FIU95_RS05960	COG1063	alcohol dehydrogenase
FIU95_RS05965	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FIU95_RS05970	COG1570	exodeoxyribonuclease VII activity
FIU95_RS05980	COG0519	Catalyzes the synthesis of GMP from XMP
FIU95_RS05980	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FIU95_RS05985	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FIU95_RS05995	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FIU95_RS06000	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FIU95_RS06010	COG2350	Protein conserved in bacteria
FIU95_RS06020	COG0613	PHP domain protein
FIU95_RS06025	COG0009	L-threonylcarbamoyladenylate synthase
FIU95_RS06035	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FIU95_RS06050	COG2205	protein histidine kinase activity
FIU95_RS06055	COG0745	RESPONSE REGULATOR receiver
FIU95_RS06065	COG0716	FMN binding
FIU95_RS06080	COG4946	Tricorn protease homolog
FIU95_RS06080	COG1506	peptidase
FIU95_RS06080	COG0823	Involved in the tonB-independent uptake of proteins
FIU95_RS06085	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FIU95_RS06090	COG2171	N-acyltransferase activity
FIU95_RS06095	COG1393	Belongs to the ArsC family
FIU95_RS06100	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FIU95_RS06110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FIU95_RS06115	COG0024	Methionine aminopeptidase
FIU95_RS06120	COG0052	Belongs to the universal ribosomal protein uS2 family
FIU95_RS06125	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FIU95_RS06130	COG0528	UMP kinase activity
FIU95_RS06135	COG0233	cytoplasmic translational termination
FIU95_RS06140	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FIU95_RS06150	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FIU95_RS06175	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FIU95_RS06180	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FIU95_RS06185	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FIU95_RS06190	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FIU95_RS06200	COG4536	flavin adenine dinucleotide binding
FIU95_RS06205	COG4137	Cytochrome C assembly protein
FIU95_RS06210	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FIU95_RS06215	COG0228	four-way junction DNA binding
FIU95_RS06220	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FIU95_RS06230	COG0335	large ribosomal subunit rRNA binding
FIU95_RS06235	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FIU95_RS06240	COG1027	Aspartate ammonia-lyase
FIU95_RS06250	COG0252	asparaginase activity
FIU95_RS06275	COG1280	lysine exporter protein (LysE YggA)
FIU95_RS06295	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FIU95_RS06345	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FIU95_RS06350	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIU95_RS06370	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FIU95_RS06385	COG1666	GTP binding
FIU95_RS06400	COG1573	uracil-dna glycosylase
FIU95_RS06405	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FIU95_RS06440	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FIU95_RS06470	COG3086	response to oxidative stress
FIU95_RS06475	COG4948	Mandelate Racemase Muconate Lactonizing
FIU95_RS06480	COG2866	Carboxypeptidase
FIU95_RS06485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FIU95_RS06490	COG0481	GTPase activity
FIU95_RS06505	COG0571	ribonuclease III activity
FIU95_RS06510	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FIU95_RS06520	COG0736	holo-[acyl-carrier-protein] synthase activity
FIU95_RS06525	COG0784	Response regulator, receiver
FIU95_RS06525	COG2205	protein histidine kinase activity
FIU95_RS06525	COG5002	protein histidine kinase activity
FIU95_RS06535	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FIU95_RS06540	COG3956	TIGRFAM MazG family protein
FIU95_RS06545	COG0563	adenylate kinase activity
FIU95_RS06550	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FIU95_RS06560	COG1214	PFAM Peptidase M22, glycoprotease
FIU95_RS06570	COG2084	Dehydrogenase
FIU95_RS06610	COG2264	protein methyltransferase activity
FIU95_RS06660	COG1628	Protein of unknown function DUF99
FIU95_RS06670	COG3122	Protein conserved in bacteria
FIU95_RS06680	COG2267	carboxylic ester hydrolase activity
FIU95_RS06685	COG1595	DNA-templated transcription, initiation
FIU95_RS06690	COG4771	TonB-dependent receptor
FIU95_RS06705	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FIU95_RS06710	COG2974	May be involved in recombination
FIU95_RS06740	COG0346	lactoylglutathione lyase activity
FIU95_RS06770	COG2195	Cleaves the N-terminal amino acid of tripeptides
FIU95_RS06785	COG0612	Peptidase, M16
FIU95_RS06795	COG1228	amidohydrolase
FIU95_RS06800	COG2968	Membrane
FIU95_RS06810	COG0346	lactoylglutathione lyase activity
FIU95_RS06830	COG0174	glutamine synthetase
FIU95_RS06865	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FIU95_RS06870	COG1522	sequence-specific DNA binding
FIU95_RS06900	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FIU95_RS06915	COG1028	Short-chain dehydrogenase reductase Sdr
FIU95_RS06925	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FIU95_RS06930	COG0402	S-adenosylhomocysteine deaminase activity
FIU95_RS06940	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FIU95_RS06945	COG1605	Chorismate mutase
FIU95_RS06945	COG0077	Prephenate dehydratase
FIU95_RS06950	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FIU95_RS06955	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FIU95_RS06965	COG0776	regulation of translation
FIU95_RS06975	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FIU95_RS06980	COG0284	orotidine-5'-phosphate decarboxylase activity
FIU95_RS06985	COG1555	photosystem II stabilization
FIU95_RS06990	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FIU95_RS07010	COG0556	nucleotide-excision repair
FIU95_RS07020	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FIU95_RS07025	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FIU95_RS07030	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FIU95_RS07035	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FIU95_RS07040	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FIU95_RS07045	COG0072	phenylalanine-tRNA ligase activity
FIU95_RS07050	COG0776	regulation of translation
FIU95_RS07080	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FIU95_RS07105	COG3279	Response regulator of the LytR AlgR family
FIU95_RS07110	COG3275	phosphorelay sensor kinase activity
FIU95_RS07115	COG0596	Alpha beta hydrolase
FIU95_RS07120	COG0531	amino acid
FIU95_RS07125	COG3397	chitin binding
FIU95_RS07145	COG0657	acetylesterase activity
FIU95_RS07160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIU95_RS07165	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FIU95_RS07190	COG1522	sequence-specific DNA binding
FIU95_RS07205	COG1595	DNA-templated transcription, initiation
FIU95_RS07215	COG4221	oxidoreductase activity
FIU95_RS07230	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FIU95_RS07245	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FIU95_RS07250	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIU95_RS07260	COG1064	alcohol dehydrogenase
FIU95_RS07275	COG2207	Transcriptional regulator
FIU95_RS07305	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FIU95_RS07325	COG0318	PFAM AMP-dependent synthetase and ligase
FIU95_RS07330	COG0318	PFAM AMP-dependent synthetase and ligase
FIU95_RS07340	COG3621	Patatin-like phospholipase
FIU95_RS07415	COG0210	DNA helicase
FIU95_RS07435	COG0640	Transcriptional regulator
FIU95_RS07480	COG3344	reverse transcriptase
FIU95_RS07590	COG3344	reverse transcriptase
FIU95_RS07620	COG3279	Response regulator of the LytR AlgR family
FIU95_RS07625	COG3275	phosphorelay sensor kinase activity
FIU95_RS07640	COG2301	Belongs to the HpcH HpaI aldolase family
FIU95_RS07645	COG0427	acetyl-CoA hydrolase
FIU95_RS07650	COG3634	alkyl hydroperoxide reductase activity
FIU95_RS07660	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FIU95_RS07695	COG0702	epimerase
FIU95_RS07710	COG2814	Major facilitator Superfamily
FIU95_RS07745	COG0604	alcohol dehydrogenase
FIU95_RS07765	COG3063	Type IV pilus biogenesis stability protein PilW
FIU95_RS07775	COG0811	peptide transport
FIU95_RS07830	COG3655	Transcriptional regulator
FIU95_RS07845	COG1233	COG1233 Phytoene dehydrogenase and related
FIU95_RS07860	COG0739	heme binding
FIU95_RS07865	COG0477	Major facilitator Superfamily
FIU95_RS07935	COG0531	amino acid
FIU95_RS07940	COG1982	Orn Lys Arg decarboxylase major
FIU95_RS07945	COG0028	Belongs to the TPP enzyme family
FIU95_RS07960	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FIU95_RS07985	COG1088	dTDP-glucose 4,6-dehydratase activity
FIU95_RS07990	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FIU95_RS07995	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FIU95_RS08000	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FIU95_RS08005	COG0215	cysteine-tRNA ligase activity
FIU95_RS08040	COG1956	GAF domain-containing protein
FIU95_RS08045	COG2264	protein methyltransferase activity
FIU95_RS08055	COG2813	Specifically methylates the guanine in position
FIU95_RS08060	COG1187	pseudouridine synthase activity
FIU95_RS08065	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FIU95_RS08170	COG0740	serine-type endopeptidase activity
FIU95_RS08240	COG0584	glycerophosphoryl diester phosphodiesterase
FIU95_RS08255	COG0529	Catalyzes the synthesis of activated sulfate
FIU95_RS08280	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FIU95_RS08340	COG0438	transferase activity, transferring glycosyl groups
FIU95_RS08350	COG2304	oxidoreductase activity
FIU95_RS08370	COG0714	Associated with various cellular activities
FIU95_RS08380	COG0167	dihydroorotate dehydrogenase activity
FIU95_RS08385	COG3130	regulation of translation
FIU95_RS08395	COG0116	Belongs to the methyltransferase superfamily
FIU95_RS08395	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FIU95_RS08400	COG0515	serine threonine protein kinase
FIU95_RS08400	COG2815	serine threonine protein kinase
FIU95_RS08420	COG0741	lytic transglycosylase activity
FIU95_RS08425	COG0488	(ABC) transporter
FIU95_RS08430	COG0589	response to stress
FIU95_RS08455	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FIU95_RS08465	COG0318	PFAM AMP-dependent synthetase and ligase
FIU95_RS08475	COG1472	Belongs to the glycosyl hydrolase 3 family
FIU95_RS08480	COG0668	transmembrane transport
FIU95_RS08485	COG1278	Cold shock
FIU95_RS08495	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FIU95_RS08505	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FIU95_RS08510	COG1805	sodium ion transport
FIU95_RS08525	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FIU95_RS08530	COG2871	sodium ion transport
FIU95_RS08535	COG1477	protein flavinylation
FIU95_RS08550	COG2050	protein possibly involved in aromatic compounds catabolism
FIU95_RS08555	COG0456	acetyltransferase
FIU95_RS08590	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FIU95_RS08595	COG0432	Pfam Uncharacterised protein family UPF0047
FIU95_RS08600	COG2920	part of a sulfur-relay system
FIU95_RS08605	COG2168	tRNA wobble position uridine thiolation
FIU95_RS08610	COG2923	Belongs to the DsrF TusC family
FIU95_RS08615	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FIU95_RS08620	COG0670	Belongs to the BI1 family
FIU95_RS08640	COG0398	Pfam SNARE associated Golgi protein
FIU95_RS08685	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIU95_RS08700	COG1530	ribonuclease E activity
FIU95_RS08715	COG0546	phosphoglycolate phosphatase activity
FIU95_RS08720	COG0424	maF-like protein
FIU95_RS08725	COG1399	metal-binding, possibly nucleic acid-binding protein
FIU95_RS08730	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FIU95_RS08735	COG0416	fatty acid biosynthetic process
FIU95_RS08750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FIU95_RS08755	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FIU95_RS08765	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FIU95_RS08770	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FIU95_RS08785	COG0084	hydrolase, TatD family'
FIU95_RS08795	COG0039	L-malate dehydrogenase activity
FIU95_RS08805	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FIU95_RS08815	COG1862	Preprotein translocase
FIU95_RS08820	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FIU95_RS08825	COG1115	amino acid carrier protein
FIU95_RS08835	COG0174	glutamine synthetase
FIU95_RS08840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU95_RS08845	COG1309	transcriptional regulator
FIU95_RS08865	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FIU95_RS08870	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FIU95_RS08885	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FIU95_RS08900	COG0427	acetyl-CoA hydrolase
FIU95_RS08905	COG0857	belongs to the CobB CobQ family
FIU95_RS08905	COG0280	phosphate acetyltransferase
FIU95_RS08910	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FIU95_RS08925	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FIU95_RS08940	COG1566	PFAM secretion protein HlyD family protein
FIU95_RS08970	COG2153	protein acetylation
FIU95_RS08975	COG2850	peptidyl-arginine hydroxylation
FIU95_RS08985	COG2915	High frequency lysogenization protein hflD homolog
FIU95_RS09005	COG1278	Cold shock
FIU95_RS09010	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FIU95_RS09015	COG0542	response to heat
FIU95_RS09020	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FIU95_RS09025	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FIU95_RS09030	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FIU95_RS09035	COG0492	ferredoxin-NADP+ reductase activity
FIU95_RS09040	COG2226	methyltransferase
FIU95_RS09050	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FIU95_RS09055	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FIU95_RS09060	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FIU95_RS09065	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FIU95_RS09070	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FIU95_RS09070	COG1648	precorrin-2 dehydrogenase activity
FIU95_RS09090	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FIU95_RS09095	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FIU95_RS09105	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FIU95_RS09125	COG0429	hydrolase of the alpha beta-hydrolase fold
FIU95_RS09130	COG2226	methyltransferase
FIU95_RS09135	COG1595	DNA-templated transcription, initiation
FIU95_RS09210	COG3158	transport of potassium into the cell
FIU95_RS09230	COG3604	Transcriptional regulator
FIU95_RS09270	COG0789	Transcriptional regulator
FIU95_RS09275	COG1408	metallophosphoesterase
FIU95_RS09300	COG1215	transferase activity, transferring glycosyl groups
FIU95_RS09305	COG0183	Belongs to the thiolase family
FIU95_RS09310	COG3540	Alkaline phosphatase
FIU95_RS09315	COG1012	belongs to the aldehyde dehydrogenase family
FIU95_RS09350	COG0583	DNA-binding transcription factor activity
FIU95_RS09360	COG1215	transferase activity, transferring glycosyl groups
FIU95_RS09370	COG0513	Belongs to the DEAD box helicase family
FIU95_RS09380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU95_RS09420	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIU95_RS09445	COG5183	chlorophyll binding
FIU95_RS09445	COG2133	pyrroloquinoline quinone binding
FIU95_RS09450	COG1858	cytochrome C peroxidase
FIU95_RS09455	COG0604	alcohol dehydrogenase
FIU95_RS09455	COG3321	synthase
FIU95_RS09465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FIU95_RS09470	COG0583	DNA-binding transcription factor activity
FIU95_RS09505	COG0069	glutamate synthase activity
FIU95_RS09515	COG1733	regulation of RNA biosynthetic process
FIU95_RS09520	COG1028	Short-chain dehydrogenase reductase Sdr
FIU95_RS09545	COG3459	Glycosyltransferase 36 associated
FIU95_RS09575	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FIU95_RS09600	COG0409	Hydrogenase expression formation protein
FIU95_RS09605	COG0298	carbon dioxide binding
FIU95_RS09610	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FIU95_RS09635	COG0543	2 iron, 2 sulfur cluster binding
FIU95_RS09710	COG0702	epimerase
FIU95_RS09715	COG1012	belongs to the aldehyde dehydrogenase family
FIU95_RS09725	COG3431	PFAM Phosphate-starvation-inducible E
FIU95_RS09745	COG1917	Cupin 2, conserved barrel domain protein
FIU95_RS09750	COG0527	aspartate kinase activity
FIU95_RS09760	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FIU95_RS09765	COG1012	belongs to the aldehyde dehydrogenase family
FIU95_RS09795	COG1278	Cold shock
FIU95_RS09800	COG0557	exoribonuclease II activity
FIU95_RS09805	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIU95_RS09810	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIU95_RS09845	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FIU95_RS09855	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU95_RS09865	COG1309	transcriptional regulator
FIU95_RS09875	COG3811	Belongs to the UPF0386 family
FIU95_RS09920	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FIU95_RS09930	COG1609	Transcriptional regulator
FIU95_RS09955	COG3040	lipid binding
FIU95_RS09960	COG0793	Belongs to the peptidase S41A family
FIU95_RS09965	COG0708	Exodeoxyribonuclease III
FIU95_RS09975	COG0640	Transcriptional regulator
FIU95_RS09980	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FIU95_RS09990	COG0726	polysaccharide deacetylase
FIU95_RS09995	COG3038	cytochrome b561
FIU95_RS10040	COG0784	Response regulator, receiver
FIU95_RS10040	COG2205	protein histidine kinase activity
FIU95_RS10065	COG3156	type II secretion system protein K
FIU95_RS10145	COG1946	Acyl-CoA thioesterase
FIU95_RS10165	COG1404	Belongs to the peptidase S8 family
FIU95_RS10190	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FIU95_RS10225	COG0322	excinuclease ABC activity
FIU95_RS10235	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FIU95_RS10240	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FIU95_RS10245	COG1663	tetraacyldisaccharide 4'-kinase activity
FIU95_RS10250	COG1132	(ABC) transporter
FIU95_RS10255	COG0848	biopolymer transport protein
FIU95_RS10260	COG0811	peptide transport
FIU95_RS10275	COG2079	MmgE PrpD family protein
FIU95_RS10285	COG0826	peptidase U32
FIU95_RS10295	COG1136	(ABC) transporter
FIU95_RS10310	COG0393	Putative heavy-metal-binding
FIU95_RS10330	COG2373	Large extracellular alpha-helical protein
FIU95_RS10335	COG4953	penicillin-binding protein 1C
FIU95_RS10345	COG1846	Transcriptional regulator
FIU95_RS10365	COG0778	Nitroreductase
FIU95_RS10410	COG0372	Belongs to the citrate synthase family
FIU95_RS10415	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FIU95_RS10430	COG4591	ABC-type transport system involved in lipoprotein release permease component
FIU95_RS10435	COG1136	(ABC) transporter
FIU95_RS10460	COG0017	Asparaginyl-tRNA synthetase
FIU95_RS10490	COG0739	heme binding
FIU95_RS10520	COG1309	transcriptional regulator
FIU95_RS10525	COG3033	Beta-eliminating lyase
FIU95_RS10540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIU95_RS10560	COG1522	sequence-specific DNA binding
FIU95_RS10565	COG4651	solute:proton antiporter activity
FIU95_RS10565	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FIU95_RS10610	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIU95_RS10620	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FIU95_RS10640	COG4106	trans-aconitate 2-methyltransferase activity
FIU95_RS10645	COG0500	methyltransferase
FIU95_RS10650	COG1760	l-serine dehydratase
FIU95_RS10685	COG0583	DNA-binding transcription factor activity
FIU95_RS10690	COG1028	Short-chain dehydrogenase reductase Sdr
FIU95_RS10695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FIU95_RS10700	COG2072	flavoprotein involved in K transport
FIU95_RS10720	COG0076	glutamate decarboxylase activity
FIU95_RS10725	COG0531	amino acid
FIU95_RS10735	COG0742	ribosomal rna small subunit methyltransferase
FIU95_RS10760	COG2900	Belongs to the SlyX family
FIU95_RS10775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FIU95_RS10780	COG0023	Translation Initiation Factor
FIU95_RS10790	COG1309	transcriptional regulator
FIU95_RS10795	COG1028	Short-chain dehydrogenase reductase Sdr
FIU95_RS10800	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FIU95_RS10805	COG1960	acyl-CoA dehydrogenase activity
FIU95_RS10820	COG1960	acyl-CoA dehydrogenase activity
FIU95_RS10890	COG1322	Protein conserved in bacteria
FIU95_RS10905	COG1074	ATP-dependent DNA helicase activity
FIU95_RS10920	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FIU95_RS10945	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FIU95_RS10980	COG2197	response regulator
FIU95_RS10985	COG4585	Histidine kinase
FIU95_RS11025	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FIU95_RS11055	COG1643	Atp-dependent helicase
FIU95_RS11080	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIU95_RS11085	COG1024	Enoyl-CoA hydratase
FIU95_RS11115	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FIU95_RS11115	COG0316	Belongs to the HesB IscA family
FIU95_RS11125	COG2130	NADP-dependent
FIU95_RS11245	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FIU95_RS11260	COG3541	Predicted nucleotidyltransferase
FIU95_RS11270	COG4771	TonB-dependent receptor
FIU95_RS11290	COG3344	reverse transcriptase
FIU95_RS11310	COG0500	methyltransferase
FIU95_RS11345	COG1115	amino acid carrier protein
FIU95_RS11350	COG3246	L-lysine catabolic process to acetate
FIU95_RS11365	COG2207	Transcriptional regulator
FIU95_RS11430	COG1752	Esterase of the alpha-beta hydrolase superfamily
FIU95_RS11470	COG3119	arylsulfatase activity
FIU95_RS11535	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIU95_RS11540	COG1960	acyl-CoA dehydrogenase activity
FIU95_RS11570	COG0318	PFAM AMP-dependent synthetase and ligase
FIU95_RS11600	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FIU95_RS11615	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FIU95_RS11615	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FIU95_RS11615	COG0506	proline dehydrogenase activity
FIU95_RS11625	COG3344	reverse transcriptase
FIU95_RS11635	COG3344	reverse transcriptase
FIU95_RS11670	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FIU95_RS11690	COG1609	Transcriptional regulator
FIU95_RS11705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIU95_RS11720	COG1611	Belongs to the LOG family
FIU95_RS11745	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIU95_RS11750	COG1280	lysine exporter protein (LysE YggA)
FIU95_RS11780	COG1429	ligase activity, forming nitrogen-metal bonds
FIU95_RS11810	COG1397	ADP-ribosylglycohydrolase
FIU95_RS11865	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FIU95_RS11890	COG2133	pyrroloquinoline quinone binding
FIU95_RS11895	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FIU95_RS11915	COG0457	Tetratricopeptide repeat
FIU95_RS11920	COG4771	TonB-dependent receptor
FIU95_RS11930	COG0339	signal peptide processing
FIU95_RS11935	COG0500	methyltransferase
FIU95_RS11950	COG1960	acyl-CoA dehydrogenase activity
FIU95_RS11955	COG1960	acyl-CoA dehydrogenase activity
FIU95_RS11960	COG0318	PFAM AMP-dependent synthetase and ligase
FIU95_RS11965	COG0183	Belongs to the thiolase family
FIU95_RS11970	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIU95_RS11970	COG1024	Enoyl-CoA hydratase
FIU95_RS12015	COG1280	lysine exporter protein (LysE YggA)
FIU95_RS12055	COG3344	reverse transcriptase
FIU95_RS12100	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FIU95_RS12105	COG1448	Aminotransferase
FIU95_RS12115	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FIU95_RS12120	COG0625	glutathione transferase activity
FIU95_RS12150	COG1595	DNA-templated transcription, initiation
FIU95_RS12165	COG0848	biopolymer transport protein
FIU95_RS12275	COG3788	relative of glutathione S-transferase, MAPEG superfamily
FIU95_RS12285	COG1228	amidohydrolase
FIU95_RS12295	COG0784	Response regulator, receiver
FIU95_RS12295	COG4191	Histidine kinase
FIU95_RS12300	COG0754	glutathionylspermidine amidase activity
FIU95_RS12305	COG5463	Belongs to the UPF0441 family
FIU95_RS12325	COG1842	Phage shock protein A
FIU95_RS12360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU95_RS12375	COG3012	SEC-C Motif Domain Protein
FIU95_RS12385	COG1690	Belongs to the RtcB family
FIU95_RS12400	COG0604	alcohol dehydrogenase
FIU95_RS12405	COG0616	signal peptide processing
FIU95_RS12415	COG2816	NAD+ diphosphatase activity
FIU95_RS12425	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FIU95_RS12435	COG0328	RNA-DNA hybrid ribonuclease activity
FIU95_RS12440	COG2226	methyltransferase
FIU95_RS12445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIU95_RS12450	COG1388	LysM domain
FIU95_RS12450	COG0741	lytic transglycosylase activity
FIU95_RS12455	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FIU95_RS12465	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FIU95_RS12475	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FIU95_RS12480	COG0740	serine-type endopeptidase activity
FIU95_RS12485	COG0544	peptidyl-prolyl cis-trans isomerase activity
FIU95_RS12495	COG0183	Belongs to the thiolase family
FIU95_RS12500	COG1024	Enoyl-CoA hydratase
FIU95_RS12500	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIU95_RS12515	COG4977	sequence-specific DNA binding
FIU95_RS12515	COG1917	Cupin 2, conserved barrel domain protein
FIU95_RS12555	COG3768	UPF0283 membrane protein
FIU95_RS12560	COG3106	COG3106 Predicted ATPase
FIU95_RS12570	COG0537	adenosine 5'-monophosphoramidase activity
FIU95_RS12580	COG1047	Peptidyl-prolyl cis-trans
FIU95_RS12585	COG3011	Protein conserved in bacteria
FIU95_RS12590	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FIU95_RS12595	COG3279	Response regulator of the LytR AlgR family
FIU95_RS12605	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FIU95_RS12610	COG0084	hydrolase, TatD family'
FIU95_RS12625	COG2866	Carboxypeptidase
FIU95_RS12650	COG0318	PFAM AMP-dependent synthetase and ligase
FIU95_RS12660	COG1960	acyl-CoA dehydrogenase activity
FIU95_RS12690	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FIU95_RS12695	COG3115	cell septum assembly
FIU95_RS12780	COG4774	siderophore transport
FIU95_RS12785	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FIU95_RS12805	COG2977	Belongs to the P-Pant transferase superfamily
FIU95_RS12825	COG1739	Uncharacterized protein family UPF0029
FIU95_RS12840	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FIU95_RS12860	COG4133	protoheme IX ABC transporter activity
FIU95_RS12935	COG0758	DNA mediated transformation
FIU95_RS13100	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FIU95_RS13180	COG0778	Nitroreductase
FIU95_RS13190	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FIU95_RS13195	COG1845	cytochrome c oxidase, subunit III
FIU95_RS13200	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FIU95_RS13205	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FIU95_RS13220	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FIU95_RS13220	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FIU95_RS13225	COG0842	Transport permease protein
FIU95_RS13230	COG1131	(ABC) transporter
FIU95_RS13270	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIU95_RS13275	COG0436	Aminotransferase
FIU95_RS13295	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FIU95_RS13300	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FIU95_RS13300	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FIU95_RS13305	COG3101	peptidyl-lysine hydroxylation
FIU95_RS13315	COG0425	Belongs to the sulfur carrier protein TusA family
FIU95_RS13330	COG3089	Belongs to the UPF0270 family
FIU95_RS13340	COG0011	TIGRFAM Protein of
FIU95_RS13350	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FIU95_RS13355	COG0716	FMN binding
FIU95_RS13400	COG0271	Belongs to the BolA IbaG family
FIU95_RS13405	COG0484	heat shock protein binding
FIU95_RS13425	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FIU95_RS13475	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FIU95_RS13480	COG0511	ligase activity, forming carbon-carbon bonds
FIU95_RS13480	COG5016	pyruvate
FIU95_RS13490	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FIU95_RS13505	COG1136	(ABC) transporter
FIU95_RS13525	COG1252	NADH dehydrogenase
FIU95_RS13530	COG0709	Synthesizes selenophosphate from selenide and ATP
FIU95_RS13545	COG0436	Aminotransferase
FIU95_RS13550	COG0154	amidase activity
FIU95_RS13555	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FIU95_RS13560	COG3279	Response regulator of the LytR AlgR family
FIU95_RS13615	COG1940	carbohydrate kinase activity
FIU95_RS13660	COG0443	Heat shock 70 kDa protein
FIU95_RS13665	COG0659	secondary active sulfate transmembrane transporter activity
FIU95_RS13670	COG0259	pyridoxamine-phosphate oxidase activity
FIU95_RS13695	COG1063	alcohol dehydrogenase
FIU95_RS13720	COG0025	NhaP-type Na H and K H
FIU95_RS13745	COG0596	Alpha beta hydrolase
FIU95_RS13760	COG0500	methyltransferase
FIU95_RS13800	COG1960	acyl-CoA dehydrogenase activity
FIU95_RS13850	COG1823	symporter activity
FIU95_RS13855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIU95_RS13860	COG1295	ribonuclease BN
FIU95_RS13865	COG1393	Belongs to the ArsC family
FIU95_RS13880	COG0616	signal peptide processing
FIU95_RS13905	COG0714	Associated with various cellular activities
FIU95_RS13920	COG1286	toxin biosynthetic process
FIU95_RS13930	COG0285	dihydrofolate synthase activity
FIU95_RS13935	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FIU95_RS13940	COG0159	tryptophan synthase activity
FIU95_RS13950	COG0135	phosphoribosylanthranilate isomerase activity
FIU95_RS13975	COG0473	3-isopropylmalate dehydrogenase activity
FIU95_RS13980	COG0066	3-isopropylmalate dehydratase activity
FIU95_RS13985	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FIU95_RS14010	COG4326	sporulation control protein
FIU95_RS14030	COG0346	lactoylglutathione lyase activity
FIU95_RS14060	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FIU95_RS14085	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FIU95_RS14115	COG1028	Short-chain dehydrogenase reductase Sdr
FIU95_RS14125	COG1960	acyl-CoA dehydrogenase activity
FIU95_RS14140	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIU95_RS14140	COG1902	pentaerythritol trinitrate reductase activity
FIU95_RS14145	COG2211	Major facilitator Superfamily
FIU95_RS14155	COG2272	Belongs to the type-B carboxylesterase lipase family
FIU95_RS14165	COG0308	aminopeptidase N
FIU95_RS14185	COG3784	Protein of unknown function (DUF1318)
FIU95_RS14205	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FIU95_RS14210	COG0585	pseudouridine synthase activity
FIU95_RS14215	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FIU95_RS14225	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FIU95_RS14230	COG0148	phosphopyruvate hydratase activity
FIU95_RS14240	COG0504	CTP synthase activity
FIU95_RS14245	COG0037	tRNA processing
FIU95_RS14250	COG1472	Belongs to the glycosyl hydrolase 3 family
FIU95_RS14260	COG2972	Histidine kinase
FIU95_RS14265	COG3279	Response regulator of the LytR AlgR family
FIU95_RS14275	COG0825	malonyl-CoA metabolic process
FIU95_RS14295	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FIU95_RS14335	COG1028	Short-chain dehydrogenase reductase Sdr
FIU95_RS14340	COG5265	(ABC) transporter
FIU95_RS14365	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FIU95_RS14370	COG2890	protein-(glutamine-N5) methyltransferase activity
FIU95_RS14375	COG0302	gtp cyclohydrolase
FIU95_RS14390	COG2062	phosphohistidine phosphatase, SixA
FIU95_RS14400	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FIU95_RS14405	COG0326	Molecular chaperone. Has ATPase activity
FIU95_RS14415	COG0450	alkyl hydroperoxide reductase
FIU95_RS14420	COG2906	2 iron, 2 sulfur cluster binding
FIU95_RS14435	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FIU95_RS14445	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FIU95_RS14460	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FIU95_RS14505	COG0471	metal ion transport
FIU95_RS14520	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FIU95_RS14525	COG0656	L-ascorbic acid biosynthetic process
FIU95_RS14540	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FIU95_RS14570	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FIU95_RS14580	COG0534	Mate efflux family protein
FIU95_RS14600	COG0045	succinate-CoA ligase (ADP-forming) activity
FIU95_RS14625	COG1053	succinate dehydrogenase
FIU95_RS14630	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FIU95_RS14635	COG2009	succinate dehydrogenase
FIU95_RS14650	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FIU95_RS14665	COG3530	Putative quorum-sensing-regulated virulence factor
FIU95_RS14705	COG2072	flavoprotein involved in K transport
FIU95_RS14710	COG4221	oxidoreductase activity
FIU95_RS14710	COG3321	synthase
FIU95_RS14710	COG0300	oxidoreductase activity
FIU95_RS14710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FIU95_RS14800	COG2081	HI0933 family
FIU95_RS14805	COG0717	Belongs to the dCTP deaminase family
FIU95_RS14820	COG4969	Belongs to the N-Me-Phe pilin family
FIU95_RS14840	COG0237	dephospho-CoA kinase activity
FIU95_RS14845	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FIU95_RS14850	COG0494	nUDIX hydrolase
FIU95_RS14855	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FIU95_RS14860	COG0653	protein targeting
FIU95_RS14865	COG0739	heme binding
FIU95_RS14870	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FIU95_RS14875	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FIU95_RS14890	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FIU95_RS14895	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FIU95_RS14900	COG0772	Belongs to the SEDS family
FIU95_RS14905	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FIU95_RS14910	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FIU95_RS14915	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FIU95_RS14920	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FIU95_RS14935	COG0275	rRNA processing
FIU95_RS14940	COG2001	Belongs to the MraZ family
FIU95_RS14955	COG3107	peptidoglycan biosynthetic process
FIU95_RS14960	COG0792	nuclease activity
FIU95_RS14965	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FIU95_RS14980	COG1704	LemA family
FIU95_RS14985	COG0501	Belongs to the peptidase M48B family
FIU95_RS15000	COG5487	UPF0391 membrane protein
FIU95_RS15010	COG2204	response regulator
FIU95_RS15020	COG4251	negative regulation of phosphorylation
FIU95_RS15025	COG0784	Response regulator, receiver
FIU95_RS15030	COG0784	Response regulator, receiver
FIU95_RS15030	COG2198	Histidine kinase
FIU95_RS15030	COG5002	protein histidine kinase activity
FIU95_RS15035	COG0628	permease
FIU95_RS15065	COG2885	chlorophyll binding
FIU95_RS15070	COG2969	positive regulation of protein catabolic process
FIU95_RS15075	COG0625	glutathione transferase activity
FIU95_RS15080	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FIU95_RS15085	COG0723	plastoquinol--plastocyanin reductase activity
FIU95_RS15090	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FIU95_RS15095	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FIU95_RS15100	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FIU95_RS15110	COG2046	Belongs to the sulfate adenylyltransferase family
FIU95_RS15115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FIU95_RS15135	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FIU95_RS15140	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FIU95_RS15160	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FIU95_RS15170	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FIU95_RS15175	COG1137	ATPase activity
FIU95_RS15185	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FIU95_RS15195	COG1660	Displays ATPase and GTPase activities
FIU95_RS15200	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU95_RS15205	COG2239	Acts as a magnesium transporter
FIU95_RS15210	COG3028	Belongs to the UPF0307 family
FIU95_RS15215	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIU95_RS15230	COG0424	maF-like protein
FIU95_RS15240	COG1792	Involved in formation and maintenance of cell shape
FIU95_RS15245	COG1077	Cell shape determining protein MreB Mrl
FIU95_RS15250	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FIU95_RS15255	COG0154	amidase activity
FIU95_RS15260	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FIU95_RS15300	COG0534	Mate efflux family protein
FIU95_RS15305	COG3608	succinylglutamate desuccinylase aspartoacylase
FIU95_RS15315	COG2890	protein-(glutamine-N5) methyltransferase activity
FIU95_RS15320	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FIU95_RS15340	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FIU95_RS15350	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FIU95_RS15355	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FIU95_RS15360	COG0193	aminoacyl-tRNA hydrolase activity
FIU95_RS15455	COG4104	PAAR repeat-containing protein
FIU95_RS15455	COG3209	COG3209 Rhs family protein
FIU95_RS15470	COG3209	COG3209 Rhs family protein
FIU95_RS15485	COG0469	pyruvate kinase activity
FIU95_RS15495	COG0800	Aldolase
FIU95_RS15505	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FIU95_RS15520	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FIU95_RS15525	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FIU95_RS15535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIU95_RS15545	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FIU95_RS15555	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FIU95_RS15560	COG1702	phosphate starvation-inducible protein PhoH
FIU95_RS15575	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FIU95_RS15580	COG1090	epimerase
FIU95_RS15600	COG0495	leucyl-tRNA aminoacylation
FIU95_RS15605	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FIU95_RS15610	COG1466	dna polymerase III delta subunit
FIU95_RS15645	COG1960	acyl-CoA dehydrogenase activity
FIU95_RS15650	COG3039	Transposase
FIU95_RS15670	COG1982	Orn Lys Arg decarboxylase major
FIU95_RS15680	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
FIU95_RS15710	COG4264	IucA IucC family
FIU95_RS15730	COG0288	reversible hydration of carbon dioxide
FIU95_RS15735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FIU95_RS15740	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FIU95_RS15770	COG3240	lipase activity
FIU95_RS15770	COG4625	pathogenesis
FIU95_RS15775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FIU95_RS15790	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FIU95_RS15795	COG0321	lipoyl(octanoyl) transferase activity
FIU95_RS15805	COG1686	Belongs to the peptidase S11 family
FIU95_RS15815	COG2951	lytic endotransglycosylase activity
FIU95_RS15820	COG0772	Belongs to the SEDS family
FIU95_RS15825	COG0768	penicillin binding
FIU95_RS15830	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FIU95_RS15840	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FIU95_RS15845	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FIU95_RS15855	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FIU95_RS15875	COG1619	proteins homologs of microcin C7 resistance protein MccF
FIU95_RS15910	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FIU95_RS15915	COG0205	6-phosphofructokinase activity
FIU95_RS15940	COG0793	Belongs to the peptidase S41A family
FIU95_RS15945	COG0456	acetyltransferase
FIU95_RS15975	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIU95_RS16000	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FIU95_RS16025	COG0501	Belongs to the peptidase M48B family
FIU95_RS16030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FIU95_RS16040	COG1489	DNA binding
FIU95_RS16045	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FIU95_RS16050	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FIU95_RS16055	COG3852	Histidine kinase
FIU95_RS16075	COG1428	Deoxynucleoside kinase
FIU95_RS16080	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FIU95_RS16110	COG1185	polyribonucleotide nucleotidyltransferase activity
FIU95_RS16120	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FIU95_RS16125	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FIU95_RS16130	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FIU95_RS16135	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FIU95_RS16140	COG0195	Participates in both transcription termination and antitermination
FIU95_RS16145	COG0779	Required for maturation of 30S ribosomal subunits
FIU95_RS16210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIU95_RS16215	COG2132	Multicopper oxidase
FIU95_RS16225	COG2826	transposase and inactivated derivatives, IS30 family
FIU95_RS16240	COG0582	viral genome integration into host DNA
FIU95_RS16320	COG0149	triose-phosphate isomerase activity
FIU95_RS16325	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FIU95_RS16330	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FIU95_RS16340	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FIU95_RS16360	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FIU95_RS16365	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FIU95_RS16375	COG1116	anion transmembrane transporter activity
FIU95_RS16375	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FIU95_RS16380	COG2223	nitrite transmembrane transporter activity
FIU95_RS16385	COG0515	serine threonine protein kinase
FIU95_RS16385	COG2815	serine threonine protein kinase
FIU95_RS16390	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FIU95_RS16390	COG2146	nitrite reductase [NAD(P)H] activity
FIU95_RS16395	COG2146	nitrite reductase [NAD(P)H] activity
FIU95_RS16400	COG0243	molybdopterin cofactor binding
FIU95_RS16425	COG1131	(ABC) transporter
FIU95_RS16430	COG0842	Transport permease protein
FIU95_RS16440	COG1309	transcriptional regulator
FIU95_RS16450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU95_RS16470	COG2197	response regulator
FIU95_RS16530	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FIU95_RS16535	COG0505	Belongs to the CarA family
FIU95_RS16545	COG0189	ligase activity
FIU95_RS16545	COG4067	protein conserved in archaea
FIU95_RS16550	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FIU95_RS16560	COG0484	heat shock protein binding
FIU95_RS16565	COG0443	Heat shock 70 kDa protein
FIU95_RS16570	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FIU95_RS16575	COG0497	DNA recombination
FIU95_RS16600	COG2867	negative regulation of translational initiation
FIU95_RS16605	COG0733	neurotransmitter:sodium symporter activity
FIU95_RS16610	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FIU95_RS16615	COG0733	neurotransmitter:sodium symporter activity
FIU95_RS16645	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FIU95_RS16660	COG1715	Restriction endonuclease
FIU95_RS16685	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FIU95_RS16715	COG2259	Doxx family
FIU95_RS16720	COG0435	Glutathione S-transferase
FIU95_RS16730	COG0583	DNA-binding transcription factor activity
FIU95_RS16735	COG1741	Belongs to the pirin family
FIU95_RS16755	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FIU95_RS16755	COG2111	Na H antiporter
FIU95_RS16760	COG2111	Na H antiporter
FIU95_RS16765	COG1006	Multisubunit Na H antiporter MnhC subunit
FIU95_RS16770	COG0651	ATP synthesis coupled electron transport
FIU95_RS16775	COG1863	multisubunit Na H antiporter MnhE subunit
FIU95_RS16780	COG2212	antiporter activity
FIU95_RS16785	COG1320	monovalent cation:proton antiporter activity
FIU95_RS16790	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FIU95_RS16795	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FIU95_RS16810	COG0583	DNA-binding transcription factor activity
FIU95_RS16840	COG0385	Bile acid
FIU95_RS16855	COG1271	oxidase subunit
FIU95_RS16860	COG1294	oxidase, subunit
FIU95_RS16890	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FIU95_RS16895	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FIU95_RS16920	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FIU95_RS16930	COG2824	Alkylphosphonate utilization operon protein PhnA
FIU95_RS16940	COG0071	Belongs to the small heat shock protein (HSP20) family
FIU95_RS16950	COG0204	Acyl-transferase
FIU95_RS16965	COG3038	cytochrome b561
FIU95_RS16980	COG2815	serine threonine protein kinase
FIU95_RS16980	COG0515	serine threonine protein kinase
FIU95_RS16990	COG2873	o-acetylhomoserine
FIU95_RS16995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FIU95_RS17005	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FIU95_RS17015	COG1181	Belongs to the D-alanine--D-alanine ligase family
FIU95_RS17035	COG0142	geranyltranstransferase activity
FIU95_RS17040	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FIU95_RS17050	COG1053	succinate dehydrogenase
FIU95_RS17050	COG3976	FMN-binding domain protein
FIU95_RS17060	COG4206	TonB-dependent receptor
FIU95_RS17065	COG2076	Multidrug Resistance protein
FIU95_RS17070	COG1162	GTPase activity
FIU95_RS17080	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FIU95_RS17090	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FIU95_RS17095	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FIU95_RS17100	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FIU95_RS17105	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FIU95_RS17120	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FIU95_RS17120	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FIU95_RS17125	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FIU95_RS17130	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FIU95_RS17160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FIU95_RS17165	COG1028	Short-chain dehydrogenase reductase Sdr
FIU95_RS17170	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FIU95_RS17185	COG3047	cAMP biosynthetic process
FIU95_RS17195	COG1024	Enoyl-CoA hydratase
FIU95_RS17195	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIU95_RS17200	COG0488	(ABC) transporter
FIU95_RS17205	COG1132	(ABC) transporter
FIU95_RS17210	COG1132	(ABC) transporter
FIU95_RS17235	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FIU95_RS17235	COG0519	Catalyzes the synthesis of GMP from XMP
FIU95_RS17240	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FIU95_RS17250	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FIU95_RS17260	COG4206	TonB-dependent receptor
FIU95_RS17275	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FIU95_RS17290	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FIU95_RS17300	COG0426	domain, Protein
FIU95_RS17300	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FIU95_RS17315	COG2132	Multicopper oxidase
FIU95_RS17335	COG0300	oxidoreductase activity
FIU95_RS17355	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FIU95_RS17360	COG3397	chitin binding
FIU95_RS17375	COG2217	Heavy metal translocating P-type atpase
FIU95_RS17405	COG0681	Belongs to the peptidase S26 family
FIU95_RS17415	COG2957	Belongs to the agmatine deiminase family
FIU95_RS17440	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FIU95_RS17450	COG2095	MarC family integral membrane protein
FIU95_RS17455	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
FIU95_RS17465	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FIU95_RS17470	COG0248	Ppx GppA phosphatase
FIU95_RS17475	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FIU95_RS17495	COG1598	PFAM Uncharacterised protein family UPF0150
FIU95_RS17545	COG1846	Transcriptional regulator
FIU95_RS17555	COG1116	anion transmembrane transporter activity
FIU95_RS17560	COG0390	transport system, permease component
FIU95_RS17590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIU95_RS17615	COG0709	Synthesizes selenophosphate from selenide and ATP
FIU95_RS17620	COG1252	NADH dehydrogenase
FIU95_RS17625	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FIU95_RS17645	COG0471	metal ion transport
FIU95_RS17645	COG3273	potassium ion transport
FIU95_RS17655	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FIU95_RS17660	COG0300	oxidoreductase activity
FIU95_RS17675	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FIU95_RS17695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIU95_RS17705	COG2909	trisaccharide binding
FIU95_RS17710	COG0366	Alpha amylase catalytic
FIU95_RS17715	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FIU95_RS17725	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FIU95_RS17730	COG2326	polyphosphate kinase activity
FIU95_RS17745	COG0583	DNA-binding transcription factor activity
FIU95_RS17755	COG2814	Major facilitator Superfamily
FIU95_RS17795	COG1115	amino acid carrier protein
FIU95_RS17805	COG1501	Belongs to the glycosyl hydrolase 31 family
FIU95_RS17875	COG0642	Histidine kinase
FIU95_RS17880	COG0745	RESPONSE REGULATOR receiver
FIU95_RS17885	COG1028	Short-chain dehydrogenase reductase Sdr
FIU95_RS17905	COG0589	response to stress
FIU95_RS17910	COG0366	Alpha amylase catalytic
FIU95_RS17950	COG0837	glucose binding
FIU95_RS17955	COG3813	Protein conserved in bacteria
FIU95_RS17975	COG1473	amidohydrolase
FIU95_RS17985	COG0513	Belongs to the DEAD box helicase family
FIU95_RS17990	COG1247	-acetyltransferase
FIU95_RS18015	COG4221	oxidoreductase activity
FIU95_RS18020	COG0583	DNA-binding transcription factor activity
FIU95_RS18225	COG3150	esterase
FIU95_RS18235	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FIU95_RS18240	COG3151	Protein conserved in bacteria
FIU95_RS18245	COG0494	nUDIX hydrolase
FIU95_RS18265	COG3008	intermembrane lipid transfer
FIU95_RS18270	COG2995	paraquat-inducible protein a
FIU95_RS18275	COG2995	paraquat-inducible protein a
FIU95_RS18280	COG1538	Outer membrane efflux protein
FIU95_RS18285	COG1519	Transferase
FIU95_RS18325	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FIU95_RS18330	COG1392	Phosphate transport regulator
FIU95_RS18335	COG0306	phosphate transporter
FIU95_RS18340	COG3961	Belongs to the TPP enzyme family
FIU95_RS18355	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FIU95_RS18355	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FIU95_RS18360	COG0129	dihydroxy-acid dehydratase activity
FIU95_RS18365	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FIU95_RS18375	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FIU95_RS18380	COG0848	biopolymer transport protein
FIU95_RS18390	COG0811	peptide transport
FIU95_RS18405	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FIU95_RS18410	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FIU95_RS18430	COG2989	Protein conserved in bacteria
FIU95_RS18435	COG3108	Peptidase M15
FIU95_RS18450	COG0494	nUDIX hydrolase
FIU95_RS18455	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
FIU95_RS18460	COG0509	glycine decarboxylation via glycine cleavage system
FIU95_RS18465	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FIU95_RS18475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIU95_RS18480	COG0705	Rhomboid family
FIU95_RS18485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIU95_RS18490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIU95_RS18495	COG0006	proline dipeptidase activity
FIU95_RS18500	COG3079	Belongs to the UPF0149 family
FIU95_RS18520	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FIU95_RS18525	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FIU95_RS18530	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FIU95_RS18560	COG0183	Belongs to the thiolase family
FIU95_RS18565	COG1024	Enoyl-CoA hydratase
FIU95_RS18565	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIU95_RS18570	COG1960	acyl-CoA dehydrogenase activity
FIU95_RS18585	COG3046	protein related to deoxyribodipyrimidine photolyase
FIU95_RS18595	COG3248	Nucleoside-binding outer membrane protein
FIU95_RS18600	COG2252	PERMEase
FIU95_RS18620	COG0454	-acetyltransferase
FIU95_RS18630	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FIU95_RS18655	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIU95_RS18660	COG1012	belongs to the aldehyde dehydrogenase family
FIU95_RS18720	COG2801	Transposase and inactivated derivatives
FIU95_RS18750	COG0861	Integral membrane protein TerC family
FIU95_RS18770	COG1012	belongs to the aldehyde dehydrogenase family
FIU95_RS18775	COG0179	Fumarylacetoacetate (FAA) hydrolase
FIU95_RS18780	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FIU95_RS18790	COG3275	phosphorelay sensor kinase activity
FIU95_RS18835	COG0126	phosphoglycerate kinase activity
FIU95_RS18845	COG0612	Peptidase, M16
FIU95_RS18880	COG0596	Alpha beta hydrolase
FIU95_RS18925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIU95_RS19045	COG0714	Associated with various cellular activities
FIU95_RS19065	COG4774	siderophore transport
FIU95_RS19100	COG1011	Hydrolase
FIU95_RS19105	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FIU95_RS19110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FIU95_RS19120	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FIU95_RS19125	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FIU95_RS19140	COG0628	permease
FIU95_RS19145	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FIU95_RS19155	COG2204	response regulator
FIU95_RS19160	COG3852	Histidine kinase
FIU95_RS19170	COG0174	glutamine synthetase
FIU95_RS19175	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FIU95_RS19175	COG0301	tRNA thio-modification
FIU95_RS19180	COG1217	gtp-binding protein TYPA
FIU95_RS19210	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FIU95_RS19215	COG3706	GGDEF domain
FIU95_RS19240	COG0668	transmembrane transport
FIU95_RS19245	COG2818	Glycosylase
FIU95_RS19250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FIU95_RS19255	COG1505	serine-type exopeptidase activity
FIU95_RS19260	COG1490	D-aminoacyl-tRNA deacylase activity
FIU95_RS19330	COG1764	response to oxidative stress
FIU95_RS19335	COG0010	Belongs to the arginase family
FIU95_RS19340	COG1228	amidohydrolase
FIU95_RS19345	COG2188	Transcriptional regulator
FIU95_RS19350	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FIU95_RS19355	COG2986	histidine ammonia-lyase
FIU95_RS19370	COG0469	pyruvate kinase activity
FIU95_RS19400	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FIU95_RS19415	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FIU95_RS19420	COG4942	peptidase
FIU95_RS19425	COG0793	Belongs to the peptidase S41A family
FIU95_RS19430	COG0107	imidazoleglycerol-phosphate synthase activity
FIU95_RS19435	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FIU95_RS19440	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FIU95_RS19445	COG0131	Imidazoleglycerol-phosphate dehydratase
FIU95_RS19475	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FIU95_RS19530	COG1301	dicarboxylic acid transport
FIU95_RS19545	COG1012	belongs to the aldehyde dehydrogenase family
FIU95_RS19575	COG1233	COG1233 Phytoene dehydrogenase and related
FIU95_RS19580	COG2885	chlorophyll binding
FIU95_RS19585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIU95_RS19595	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FIU95_RS19605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU95_RS19610	COG2183	response to ionizing radiation
FIU95_RS19620	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FIU95_RS19625	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FIU95_RS19630	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FIU95_RS19640	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FIU95_RS19645	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FIU95_RS19680	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FIU95_RS19685	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FIU95_RS19690	COG0140	phosphoribosyl-ATP diphosphatase activity
FIU95_RS19700	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FIU95_RS19710	COG2226	methyltransferase
FIU95_RS19720	COG1785	Belongs to the alkaline phosphatase family
FIU95_RS19725	COG1785	Belongs to the alkaline phosphatase family
FIU95_RS19735	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FIU95_RS19740	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FIU95_RS19755	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FIU95_RS19770	COG0254	rRNA binding
FIU95_RS19775	COG0281	malic enzyme
FIU95_RS19785	COG2918	glutathione biosynthetic process
FIU95_RS19795	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FIU95_RS19800	COG1380	Effector of murein hydrolase LrgA
FIU95_RS19805	COG1346	cytolysis
FIU95_RS19830	COG0488	(ABC) transporter
FIU95_RS19845	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FIU95_RS19850	COG2363	Small membrane protein
FIU95_RS19860	COG2177	Part of the ABC transporter FtsEX involved in
FIU95_RS19865	COG2884	Cell division ATP-binding protein ftsE
FIU95_RS19870	COG0552	protein localization to endoplasmic reticulum
FIU95_RS19875	COG0742	ribosomal rna small subunit methyltransferase
FIU95_RS19880	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FIU95_RS19890	COG0281	malic enzyme
FIU95_RS19905	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FIU95_RS19910	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FIU95_RS19915	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FIU95_RS19920	COG2003	Belongs to the UPF0758 family
FIU95_RS19925	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FIU95_RS19930	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FIU95_RS19935	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FIU95_RS19940	COG1309	transcriptional regulator
FIU95_RS19950	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FIU95_RS19955	COG0708	Exodeoxyribonuclease III
FIU95_RS19960	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FIU95_RS19965	COG1561	YicC-like family, N-terminal region
FIU95_RS19975	COG1404	Belongs to the peptidase S8 family
FIU95_RS19980	COG1404	Belongs to the peptidase S8 family
FIU95_RS19995	COG1758	RNA polymerase activity
FIU95_RS20000	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FIU95_RS20015	COG2261	transglycosylase associated protein
FIU95_RS20020	COG0583	DNA-binding transcription factor activity
FIU95_RS20025	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FIU95_RS20030	COG1301	dicarboxylic acid transport
FIU95_RS20040	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FIU95_RS20060	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FIU95_RS20065	COG3022	response to hydroperoxide
FIU95_RS20100	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FIU95_RS20110	COG0573	inorganic phosphate transmembrane transporter activity
FIU95_RS20125	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIU95_RS20130	COG1607	acyl-coa hydrolase
FIU95_RS20145	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FIU95_RS20150	COG0210	DNA helicase
FIU95_RS20155	COG1737	Transcriptional regulator
FIU95_RS20160	COG2814	Major facilitator Superfamily
FIU95_RS20165	COG0625	glutathione transferase activity
FIU95_RS20170	COG2259	Doxx family
FIU95_RS20190	COG0025	NhaP-type Na H and K H
FIU95_RS20205	COG2267	carboxylic ester hydrolase activity
FIU95_RS20235	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FIU95_RS20240	COG1349	DNA-binding transcription factor activity
FIU95_RS20260	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FIU95_RS20265	COG0402	S-adenosylhomocysteine deaminase activity
FIU95_RS20295	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FIU95_RS20300	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FIU95_RS20305	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FIU95_RS20310	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FIU95_RS20320	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FIU95_RS20330	COG0356	it plays a direct role in the translocation of protons across the membrane
FIU95_RS20340	COG1475	DNA binding
FIU95_RS20345	COG1192	Involved in chromosome partitioning
FIU95_RS20355	COG0445	tRNA wobble uridine modification
FIU95_RS20360	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FIU95_RS20365	COG0706	membrane insertase activity
FIU95_RS20370	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FIU95_RS20375	COG0594	ribonuclease P activity
FIU95_RS20380	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FIU95_RS20440	COG4974	Belongs to the 'phage' integrase family
FIU95_RS20610	COG0629	single-stranded DNA binding
FIU95_RS20730	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FIU95_RS20925	COG1475	DNA binding