locus-tag	class	description
ERB44_RS00010	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ERB44_RS00070	COG0419	ATPase involved in DNA repair
ERB44_RS00080	COG0419	ATPase involved in DNA repair
ERB44_RS00100	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ERB44_RS00125	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ERB44_RS00135	COG1335	isochorismatase
ERB44_RS00185	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
ERB44_RS00195	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ERB44_RS00215	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ERB44_RS00220	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ERB44_RS00225	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ERB44_RS00230	COG0356	it plays a direct role in the translocation of protons across the membrane
ERB44_RS00250	COG2890	protein-(glutamine-N5) methyltransferase activity
ERB44_RS00255	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ERB44_RS00265	COG0083	homoserine kinase activity
ERB44_RS00270	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ERB44_RS00275	COG0460	homoserine dehydrogenase
ERB44_RS00280	COG0019	diaminopimelate decarboxylase activity
ERB44_RS00285	COG0018	arginyl-trna synthetase
ERB44_RS00295	COG2022	thiamine diphosphate biosynthetic process
ERB44_RS00310	COG0352	thiamine-phosphate diphosphorylase activity
ERB44_RS00320	COG0351	phosphomethylpyrimidine kinase
ERB44_RS00320	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ERB44_RS00320	COG0352	thiamine-phosphate diphosphorylase activity
ERB44_RS00325	COG3949	Membrane
ERB44_RS00330	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ERB44_RS00345	COG0577	efflux transmembrane transporter activity
ERB44_RS00345	COG1136	(ABC) transporter
ERB44_RS00350	COG0519	Catalyzes the synthesis of GMP from XMP
ERB44_RS00355	COG1012	belongs to the aldehyde dehydrogenase family
ERB44_RS00365	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ERB44_RS00370	COG1643	Atp-dependent helicase
ERB44_RS00385	COG0735	belongs to the Fur family
ERB44_RS00390	COG1121	(ABC) transporter
ERB44_RS00395	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ERB44_RS00400	COG0803	Belongs to the bacterial solute-binding protein 9 family
ERB44_RS00410	COG1253	flavin adenine dinucleotide binding
ERB44_RS00420	COG0567	Dehydrogenase, E1 component
ERB44_RS00420	COG0508	dehydrogenase complex catalyzes the overall conversion of
ERB44_RS00440	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ERB44_RS00450	COG0483	inositol monophosphate 1-phosphatase activity
ERB44_RS00470	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ERB44_RS00485	COG0183	Belongs to the thiolase family
ERB44_RS00490	COG1063	alcohol dehydrogenase
ERB44_RS00495	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ERB44_RS00540	COG1674	ftsk spoiiie
ERB44_RS00560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ERB44_RS00585	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ERB44_RS00590	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ERB44_RS00595	COG0131	Imidazoleglycerol-phosphate dehydratase
ERB44_RS00600	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ERB44_RS00610	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ERB44_RS00615	COG0471	metal ion transport
ERB44_RS00625	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ERB44_RS00630	COG2072	flavoprotein involved in K transport
ERB44_RS00635	COG2813	Specifically methylates the guanine in position
ERB44_RS00640	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ERB44_RS00645	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ERB44_RS00650	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ERB44_RS00655	COG2137	regulation of response to DNA damage stimulus
ERB44_RS00660	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ERB44_RS00670	COG1396	sequence-specific DNA binding
ERB44_RS00680	COG1546	Belongs to the CinA family
ERB44_RS00680	COG1058	Belongs to the CinA family
ERB44_RS00690	COG1674	ftsk spoiiie
ERB44_RS00695	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ERB44_RS00700	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ERB44_RS00715	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ERB44_RS00720	COG0612	Peptidase, M16
ERB44_RS00725	COG1185	polyribonucleotide nucleotidyltransferase activity
ERB44_RS00730	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ERB44_RS00760	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ERB44_RS00765	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ERB44_RS00785	COG0779	Required for maturation of 30S ribosomal subunits
ERB44_RS00795	COG0442	prolyl-tRNA aminoacylation
ERB44_RS00805	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ERB44_RS00810	COG0750	zinc metalloprotease
ERB44_RS00815	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ERB44_RS00820	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ERB44_RS00840	COG1960	acyl-CoA dehydrogenase activity
ERB44_RS00850	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ERB44_RS00865	COG0508	dehydrogenase complex catalyzes the overall conversion of
ERB44_RS00870	COG0022	dehydrogenase e1 component
ERB44_RS00890	COG0233	cytoplasmic translational termination
ERB44_RS00895	COG0528	UMP kinase activity
ERB44_RS00900	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ERB44_RS00905	COG0052	Belongs to the universal ribosomal protein uS2 family
ERB44_RS00935	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ERB44_RS00945	COG0656	L-ascorbic acid biosynthetic process
ERB44_RS00955	COG1028	Short-chain dehydrogenase reductase Sdr
ERB44_RS00965	COG2267	carboxylic ester hydrolase activity
ERB44_RS01095	COG0358	DNA primase activity
ERB44_RS01130	COG3842	ATPase activity
ERB44_RS01205	COG0789	Transcriptional regulator
ERB44_RS01215	COG0738	Major facilitator superfamily
ERB44_RS01230	COG0423	glycine-tRNA ligase activity
ERB44_RS01250	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ERB44_RS01255	COG2873	o-acetylhomoserine
ERB44_RS01275	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ERB44_RS01280	COG0154	amidase activity
ERB44_RS01285	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ERB44_RS01300	COG0483	inositol monophosphate 1-phosphatase activity
ERB44_RS01305	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ERB44_RS01310	COG0631	protein serine/threonine phosphatase activity
ERB44_RS01330	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ERB44_RS01340	COG0489	protein tyrosine kinase activity
ERB44_RS01365	COG2755	lipolytic protein G-D-S-L family
ERB44_RS01365	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ERB44_RS01395	COG0667	Aldo Keto reductase
ERB44_RS01435	COG4770	biotin carboxylase activity
ERB44_RS01440	COG0477	Major facilitator Superfamily
ERB44_RS01445	COG0438	transferase activity, transferring glycosyl groups
ERB44_RS01475	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ERB44_RS01505	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ERB44_RS01510	COG0193	aminoacyl-tRNA hydrolase activity
ERB44_RS01515	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ERB44_RS01525	COG0681	Belongs to the peptidase S26 family
ERB44_RS01545	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ERB44_RS01560	COG0488	(ABC) transporter
ERB44_RS01565	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ERB44_RS01570	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ERB44_RS01575	COG0084	hydrolase, TatD family'
ERB44_RS01605	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ERB44_RS01645	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ERB44_RS01650	COG1316	TRANSCRIPTIONal
ERB44_RS01655	COG1482	cell wall glycoprotein biosynthetic process
ERB44_RS01670	COG0288	reversible hydration of carbon dioxide
ERB44_RS01675	COG0114	fumarate hydratase activity
ERB44_RS01685	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ERB44_RS01695	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ERB44_RS01710	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ERB44_RS01720	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ERB44_RS01730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ERB44_RS01770	COG0148	phosphopyruvate hydratase activity
ERB44_RS01800	COG1079	Belongs to the binding-protein-dependent transport system permease family
ERB44_RS01805	COG4603	Belongs to the binding-protein-dependent transport system permease family
ERB44_RS01810	COG3845	ABC transporter
ERB44_RS01815	COG1744	ABC transporter substrate-binding protein PnrA-like
ERB44_RS01820	COG1473	amidohydrolase
ERB44_RS01820	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ERB44_RS01830	COG2009	succinate dehydrogenase
ERB44_RS01845	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ERB44_RS01870	COG1136	(ABC) transporter
ERB44_RS01875	COG0180	Tryptophanyl-tRNA synthetase
ERB44_RS01900	COG1131	(ABC) transporter
ERB44_RS01905	COG4716	Myosin-crossreactive antigen
ERB44_RS01910	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ERB44_RS01915	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ERB44_RS01940	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ERB44_RS01970	COG1643	Atp-dependent helicase
ERB44_RS01975	COG2066	Belongs to the glutaminase family
ERB44_RS01980	COG1090	epimerase
ERB44_RS01985	COG2169	Transcriptional regulator
ERB44_RS01985	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ERB44_RS01990	COG2838	Isocitrate dehydrogenase
ERB44_RS02000	COG2239	Acts as a magnesium transporter
ERB44_RS02005	COG0138	bifunctional purine biosynthesis protein purh
ERB44_RS02010	COG0477	Major facilitator Superfamily
ERB44_RS02035	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ERB44_RS02075	COG0028	Belongs to the TPP enzyme family
ERB44_RS02120	COG0045	succinate-CoA ligase (ADP-forming) activity
ERB44_RS02150	COG1132	(ABC) transporter
ERB44_RS02175	COG1278	Cold shock
ERB44_RS02190	COG0745	RESPONSE REGULATOR receiver
ERB44_RS02195	COG2205	protein histidine kinase activity
ERB44_RS02210	COG0459	protein refolding
ERB44_RS02230	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ERB44_RS02245	COG1404	Belongs to the peptidase S8 family
ERB44_RS02285	COG0179	Fumarylacetoacetate (FAA) hydrolase
ERB44_RS02300	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ERB44_RS02340	COG0366	Alpha amylase catalytic
ERB44_RS02350	COG4120	Belongs to the binding-protein-dependent transport system permease family
ERB44_RS02360	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ERB44_RS02365	COG0215	cysteine-tRNA ligase activity
ERB44_RS02370	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ERB44_RS02370	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ERB44_RS02390	COG5002	protein histidine kinase activity
ERB44_RS02400	COG0588	phosphoglycerate mutase activity
ERB44_RS02415	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ERB44_RS02420	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ERB44_RS02450	COG0737	Belongs to the 5'-nucleotidase family
ERB44_RS02485	COG2814	Major facilitator Superfamily
ERB44_RS02505	COG1017	nitric oxide dioxygenase activity
ERB44_RS02505	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ERB44_RS02515	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
ERB44_RS02520	COG0829	nickel cation binding
ERB44_RS02525	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ERB44_RS02530	COG0830	nickel cation binding
ERB44_RS02535	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
ERB44_RS02540	COG0804	urea catabolic process
ERB44_RS02545	COG0832	Belongs to the urease beta subunit family
ERB44_RS02550	COG0831	urea catabolic process
ERB44_RS02555	COG2801	Transposase and inactivated derivatives
ERB44_RS02570	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
ERB44_RS02580	COG2062	phosphohistidine phosphatase, SixA
ERB44_RS02585	COG0745	RESPONSE REGULATOR receiver
ERB44_RS02590	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ERB44_RS02605	COG0657	acetylesterase activity
ERB44_RS02610	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ERB44_RS02615	COG1201	RNA secondary structure unwinding
ERB44_RS02630	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ERB44_RS02640	COG0564	pseudouridine synthase activity
ERB44_RS02660	COG1902	pentaerythritol trinitrate reductase activity
ERB44_RS02705	COG0351	phosphomethylpyrimidine kinase
ERB44_RS02720	COG4585	Histidine kinase
ERB44_RS02725	COG2197	response regulator
ERB44_RS02735	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ERB44_RS02740	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ERB44_RS02740	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ERB44_RS02745	COG0662	Cupin 2, conserved barrel domain protein
ERB44_RS02760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ERB44_RS02785	COG1024	Enoyl-CoA hydratase
ERB44_RS02790	COG1024	Enoyl-CoA hydratase
ERB44_RS02805	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
ERB44_RS02825	COG1760	l-serine dehydratase
ERB44_RS02850	COG0028	Belongs to the TPP enzyme family
ERB44_RS02855	COG1115	amino acid carrier protein
ERB44_RS02870	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ERB44_RS02875	COG0778	Nitroreductase
ERB44_RS02885	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ERB44_RS02915	COG0596	Alpha beta hydrolase
ERB44_RS02930	COG1476	TRANSCRIPTIONal
ERB44_RS02935	COG3012	SEC-C Motif Domain Protein
ERB44_RS02945	COG0047	phosphoribosylformylglycinamidine synthase activity
ERB44_RS02950	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ERB44_RS02975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ERB44_RS02985	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ERB44_RS03005	COG5006	permease, DMT superfamily
ERB44_RS03025	COG2873	o-acetylhomoserine
ERB44_RS03030	COG1832	CoA-binding protein
ERB44_RS03035	COG0010	Belongs to the arginase family
ERB44_RS03045	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
ERB44_RS03060	COG2986	histidine ammonia-lyase
ERB44_RS03065	COG1228	amidohydrolase
ERB44_RS03070	COG3314	Sporulation integral membrane protein YlbJ
ERB44_RS03100	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ERB44_RS03110	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ERB44_RS03120	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ERB44_RS03160	COG1435	thymidine kinase activity
ERB44_RS03175	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ERB44_RS03185	COG1476	TRANSCRIPTIONal
ERB44_RS03190	COG0191	fructose-bisphosphate aldolase activity
ERB44_RS03215	COG0598	Magnesium transport protein CorA
ERB44_RS03225	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ERB44_RS03240	COG0708	Exodeoxyribonuclease III
ERB44_RS03250	COG0778	Nitroreductase
ERB44_RS03255	COG0366	Alpha amylase catalytic
ERB44_RS03275	COG1335	isochorismatase
ERB44_RS03320	COG1914	H( )-stimulated, divalent metal cation uptake system
ERB44_RS03325	COG0857	belongs to the CobB CobQ family
ERB44_RS03325	COG0280	phosphate acetyltransferase
ERB44_RS03330	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ERB44_RS03340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ERB44_RS03345	COG0601	transmembrane transport
ERB44_RS03350	COG0747	negative chemotaxis
ERB44_RS03360	COG2733	membrane
ERB44_RS03390	COG0306	phosphate transporter
ERB44_RS03395	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ERB44_RS03435	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ERB44_RS03460	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ERB44_RS03465	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ERB44_RS03475	COG1846	Transcriptional regulator
ERB44_RS03480	COG3590	peptidase
ERB44_RS03490	COG2094	Belongs to the DNA glycosylase MPG family
ERB44_RS03495	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ERB44_RS03515	COG0584	glycerophosphoryl diester phosphodiesterase
ERB44_RS03520	COG2610	gluconate transmembrane transporter activity
ERB44_RS03540	COG0823	Involved in the tonB-independent uptake of proteins
ERB44_RS03540	COG1506	peptidase
ERB44_RS03550	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ERB44_RS03565	COG3402	PFAM membrane-flanked domain
ERB44_RS03580	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ERB44_RS03590	COG0302	gtp cyclohydrolase
ERB44_RS03595	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ERB44_RS03610	COG0037	tRNA processing
ERB44_RS03620	COG2027	D-alanyl-D-alanine carboxypeptidase
ERB44_RS03625	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ERB44_RS03635	COG0561	phosphatase activity
ERB44_RS03640	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ERB44_RS03695	COG0584	glycerophosphoryl diester phosphodiesterase
ERB44_RS03700	COG1522	sequence-specific DNA binding
ERB44_RS03710	COG4221	oxidoreductase activity
ERB44_RS03720	COG0833	amino acid
ERB44_RS03735	COG0561	phosphatase activity
ERB44_RS03740	COG0039	L-malate dehydrogenase activity
ERB44_RS03770	COG2353	YceI-like domain
ERB44_RS03775	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ERB44_RS03800	COG0589	response to stress
ERB44_RS03810	COG1716	ATPase activity
ERB44_RS03810	COG1131	(ABC) transporter
ERB44_RS03810	COG0842	Transport permease protein
ERB44_RS03815	COG1716	ATPase activity
ERB44_RS03835	COG0515	serine threonine protein kinase
ERB44_RS03840	COG0515	serine threonine protein kinase
ERB44_RS03870	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ERB44_RS03910	COG0542	response to heat
ERB44_RS03915	COG0789	Transcriptional regulator
ERB44_RS03925	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ERB44_RS03955	COG2826	transposase and inactivated derivatives, IS30 family
ERB44_RS03975	COG3266	domain, Protein
ERB44_RS03980	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ERB44_RS03985	COG0187	DNA topoisomerase II activity
ERB44_RS03990	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
ERB44_RS03995	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ERB44_RS04005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ERB44_RS04010	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ERB44_RS04015	COG0594	ribonuclease P activity
ERB44_RS04020	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ERB44_RS04025	COG0706	membrane insertase activity
ERB44_RS04035	COG0357	Ribosomal RNA small subunit methyltransferase G
ERB44_RS04040	COG1192	Involved in chromosome partitioning
ERB44_RS04055	COG0492	ferredoxin-NADP+ reductase activity
ERB44_RS04075	COG0617	tRNA 3'-terminal CCA addition
ERB44_RS04085	COG2755	lipolytic protein G-D-S-L family
ERB44_RS04085	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ERB44_RS04095	COG1260	myo-inositol-1-phosphate synthase
ERB44_RS04110	COG1362	aminopeptidase activity
ERB44_RS04115	COG0360	Binds together with S18 to 16S ribosomal RNA
ERB44_RS04125	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ERB44_RS04130	COG0359	binds to the 23S rRNA
ERB44_RS04160	COG4067	protein conserved in archaea
ERB44_RS04160	COG0189	ligase activity
ERB44_RS04165	COG0189	ligase activity
ERB44_RS04165	COG0569	domain protein
ERB44_RS04170	COG1960	acyl-CoA dehydrogenase activity
ERB44_RS04180	COG0305	Participates in initiation and elongation during chromosome replication
ERB44_RS04210	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ERB44_RS04230	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ERB44_RS04235	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ERB44_RS04240	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ERB44_RS04265	COG3177	Filamentation induced by cAMP protein fic
ERB44_RS04280	COG1380	Effector of murein hydrolase LrgA
ERB44_RS04335	COG0252	asparaginase activity
ERB44_RS04350	COG0318	PFAM AMP-dependent synthetase and ligase
ERB44_RS04355	COG1063	alcohol dehydrogenase
ERB44_RS04360	COG0425	Belongs to the sulfur carrier protein TusA family
ERB44_RS04365	COG2391	methyltransferase activity
ERB44_RS04370	COG0789	Transcriptional regulator
ERB44_RS04375	COG1115	amino acid carrier protein
ERB44_RS04380	COG2318	DinB family
ERB44_RS04405	COG0488	(ABC) transporter
ERB44_RS04410	COG0626	cystathionine gamma-synthase activity
ERB44_RS04420	COG0384	phenazine biosynthesis protein PhzF
ERB44_RS04430	COG1028	Short-chain dehydrogenase reductase Sdr
ERB44_RS04445	COG0723	plastoquinol--plastocyanin reductase activity
ERB44_RS04445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ERB44_RS04475	COG2154	pterin-4-alpha-carbinolamine dehydratase
ERB44_RS04520	COG3842	ATPase activity
ERB44_RS04525	COG1609	Transcriptional regulator
ERB44_RS04535	COG1175	transmembrane transport
ERB44_RS04540	COG3833	ABC-type maltose transport systems, permease component
ERB44_RS04580	COG0739	heme binding
ERB44_RS04600	COG0488	(ABC) transporter
ERB44_RS04605	COG1511	domain protein
ERB44_RS04605	COG1511	domain protein
ERB44_RS04640	COG2357	RelA SpoT domain protein
ERB44_RS04650	COG0277	FAD linked oxidase domain protein
ERB44_RS04665	COG2066	Belongs to the glutaminase family
ERB44_RS04675	COG0702	epimerase
ERB44_RS04685	COG1120	ATPase activity
ERB44_RS04690	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ERB44_RS04695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ERB44_RS04705	COG2226	methyltransferase
ERB44_RS04710	COG0745	RESPONSE REGULATOR receiver
ERB44_RS04720	COG2205	protein histidine kinase activity
ERB44_RS04730	COG0583	DNA-binding transcription factor activity
ERB44_RS04745	COG1132	(ABC) transporter
ERB44_RS04755	COG0385	Bile acid
ERB44_RS04765	COG4591	ABC-type transport system involved in lipoprotein release permease component
ERB44_RS04775	COG0577	efflux transmembrane transporter activity
ERB44_RS04775	COG1136	(ABC) transporter
ERB44_RS04780	COG1309	transcriptional regulator
ERB44_RS04790	COG2197	response regulator
ERB44_RS04810	COG4585	Histidine kinase
ERB44_RS04815	COG2197	response regulator
ERB44_RS04860	COG3547	Transposase (IS116 IS110 IS902 family)
ERB44_RS04890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ERB44_RS04895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ERB44_RS04895	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ERB44_RS04900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ERB44_RS04910	COG1937	Protein conserved in bacteria
ERB44_RS04945	COG1136	(ABC) transporter
ERB44_RS04960	COG0659	secondary active sulfate transmembrane transporter activity
ERB44_RS04975	COG0534	Mate efflux family protein
ERB44_RS04990	COG0039	L-malate dehydrogenase activity
ERB44_RS05005	COG0028	Belongs to the TPP enzyme family
ERB44_RS05025	COG1012	belongs to the aldehyde dehydrogenase family
ERB44_RS05065	COG2608	mercury ion transmembrane transporter activity
ERB44_RS05070	COG1937	Protein conserved in bacteria
ERB44_RS05075	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ERB44_RS05080	COG1169	isochorismate synthase
ERB44_RS05095	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ERB44_RS05105	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ERB44_RS05110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ERB44_RS05125	COG0142	geranyltranstransferase activity
ERB44_RS05135	COG1233	COG1233 Phytoene dehydrogenase and related
ERB44_RS05140	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ERB44_RS05165	COG0702	epimerase
ERB44_RS05170	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ERB44_RS05175	COG0436	Aminotransferase
ERB44_RS05200	COG1764	response to oxidative stress
ERB44_RS05205	COG1846	Transcriptional regulator
ERB44_RS05225	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ERB44_RS05270	COG2826	transposase and inactivated derivatives, IS30 family
ERB44_RS05320	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ERB44_RS05340	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ERB44_RS05350	COG3311	Transcriptional regulator
ERB44_RS05400	COG3546	catalase activity
ERB44_RS05420	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ERB44_RS05425	COG0798	PFAM Bile acid sodium symporter
ERB44_RS05460	COG1268	BioY protein
ERB44_RS05465	COG1122	ATPase activity
ERB44_RS05540	COG1268	BioY protein
ERB44_RS05545	COG1122	ATPase activity
ERB44_RS05615	COG1122	ATPase activity
ERB44_RS05640	COG3328	transposase activity
ERB44_RS05690	COG1122	ATPase activity
ERB44_RS05790	COG1607	acyl-coa hydrolase
ERB44_RS05830	COG0270	DNA (cytosine-5-)-methyltransferase activity
ERB44_RS05835	COG4868	Belongs to the UPF0371 family
ERB44_RS05840	COG2860	membrane
ERB44_RS05845	COG2860	membrane
ERB44_RS05865	COG1012	belongs to the aldehyde dehydrogenase family
ERB44_RS05865	COG2030	dehydratase
ERB44_RS05875	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ERB44_RS05885	COG2315	Protein conserved in bacteria
ERB44_RS05890	COG1250	3-hydroxyacyl-CoA dehydrogenase
ERB44_RS05895	COG1024	Enoyl-CoA hydratase
ERB44_RS05905	COG0477	Major facilitator Superfamily
ERB44_RS05915	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ERB44_RS05920	COG2151	metal-sulfur cluster biosynthetic enzyme
ERB44_RS05925	COG3396	Phenylacetate-CoA oxygenase
ERB44_RS05930	COG3460	Phenylacetate-CoA oxygenase
ERB44_RS05935	COG3396	Phenylacetate-CoA oxygenase
ERB44_RS05960	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ERB44_RS05990	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ERB44_RS06030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ERB44_RS06050	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ERB44_RS06055	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ERB44_RS06060	COG0686	Belongs to the AlaDH PNT family
ERB44_RS06075	COG2186	Transcriptional regulator
ERB44_RS06085	COG1620	l-lactate permease
ERB44_RS06090	COG0247	lactate metabolic process
ERB44_RS06095	COG1139	Iron-sulfur cluster binding protein
ERB44_RS06100	COG1556	Lactate utilization protein
ERB44_RS06155	COG3540	Alkaline phosphatase
ERB44_RS06210	COG1024	Enoyl-CoA hydratase
ERB44_RS06225	COG0183	Belongs to the thiolase family
ERB44_RS06240	COG1115	amino acid carrier protein
ERB44_RS06255	COG3842	ATPase activity
ERB44_RS06260	COG4149	molybdate abc transporter
ERB44_RS06270	COG0628	permease
ERB44_RS06280	COG1012	belongs to the aldehyde dehydrogenase family
ERB44_RS06290	COG0069	glutamate synthase activity
ERB44_RS06300	COG1278	Cold shock
ERB44_RS06325	COG1136	(ABC) transporter
ERB44_RS06335	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ERB44_RS06355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ERB44_RS06360	COG0435	Glutathione S-transferase
ERB44_RS06365	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ERB44_RS06375	COG4770	biotin carboxylase activity
ERB44_RS06385	COG4336	lyase activity
ERB44_RS06390	COG1914	H( )-stimulated, divalent metal cation uptake system
ERB44_RS06400	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ERB44_RS06405	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ERB44_RS06410	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ERB44_RS06415	COG0776	regulation of translation
ERB44_RS06430	COG2847	Copper chaperone PCu(A)C
ERB44_RS06435	COG2837	iron assimilation
ERB44_RS06465	COG1748	Saccharopine dehydrogenase
ERB44_RS06470	COG0679	Auxin Efflux Carrier
ERB44_RS06485	COG0475	glutathione-regulated potassium exporter activity
ERB44_RS06500	COG0717	Belongs to the dCTP deaminase family
ERB44_RS06510	COG2111	Na H antiporter
ERB44_RS06510	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ERB44_RS06515	COG1006	Multisubunit Na H antiporter MnhC subunit
ERB44_RS06520	COG0651	ATP synthesis coupled electron transport
ERB44_RS06535	COG1320	monovalent cation:proton antiporter activity
ERB44_RS06565	COG2409	Drug exporters of the RND superfamily
ERB44_RS06580	COG2409	Drug exporters of the RND superfamily
ERB44_RS06585	COG0783	Belongs to the Dps family
ERB44_RS06590	COG0443	Heat shock 70 kDa protein
ERB44_RS06595	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ERB44_RS06600	COG0484	heat shock protein binding
ERB44_RS06605	COG0789	Transcriptional regulator
ERB44_RS06615	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ERB44_RS06625	COG0586	Pfam SNARE associated Golgi protein
ERB44_RS06640	COG0765	amino acid transport
ERB44_RS06645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ERB44_RS06660	COG0542	response to heat
ERB44_RS06675	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ERB44_RS06685	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ERB44_RS06720	COG4585	Histidine kinase
ERB44_RS06735	COG0151	Belongs to the GarS family
ERB44_RS06740	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ERB44_RS06750	COG1132	(ABC) transporter
ERB44_RS06755	COG1408	metallophosphoesterase
ERB44_RS06760	COG4499	WXG100 protein secretion system (Wss), protein YukC
ERB44_RS06760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ERB44_RS06780	COG3588	fructose-bisphosphate aldolase
ERB44_RS06795	COG2217	Heavy metal translocating P-type atpase
ERB44_RS06805	COG2205	protein histidine kinase activity
ERB44_RS06810	COG0745	RESPONSE REGULATOR receiver
ERB44_RS06820	COG2132	Multicopper oxidase
ERB44_RS06855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ERB44_RS06860	COG0733	neurotransmitter:sodium symporter activity
ERB44_RS06875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ERB44_RS06880	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ERB44_RS06885	COG2072	flavoprotein involved in K transport
ERB44_RS06920	COG1205	dead DEAH box helicase
ERB44_RS06920	COG1111	helicase
ERB44_RS06935	COG1054	Belongs to the UPF0176 family
ERB44_RS06940	COG2890	protein-(glutamine-N5) methyltransferase activity
ERB44_RS06950	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ERB44_RS06950	COG1754	DNA topoisomerase type I activity
ERB44_RS06970	COG0569	domain protein
ERB44_RS06975	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ERB44_RS06980	COG0123	including yeast histone deacetylase and acetoin utilization protein
ERB44_RS07000	COG0406	alpha-ribazole phosphatase activity
ERB44_RS07010	COG0785	Cytochrome C biogenesis protein
ERB44_RS07020	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ERB44_RS07045	COG0569	domain protein
ERB44_RS07045	COG2985	domain, Protein
ERB44_RS07050	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ERB44_RS07055	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ERB44_RS07060	COG3387	PFAM Glycoside hydrolase 15-related
ERB44_RS07070	COG2252	PERMEase
ERB44_RS07090	COG0022	dehydrogenase e1 component
ERB44_RS07120	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ERB44_RS07125	COG0644	oxidoreductase
ERB44_RS07130	COG0142	geranyltranstransferase activity
ERB44_RS07135	COG0537	adenosine 5'-monophosphoramidase activity
ERB44_RS07165	COG1666	GTP binding
ERB44_RS07175	COG0318	PFAM AMP-dependent synthetase and ligase
ERB44_RS07200	COG1228	amidohydrolase
ERB44_RS07230	COG2030	dehydratase
ERB44_RS07240	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ERB44_RS07245	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ERB44_RS07260	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ERB44_RS07270	COG0494	nUDIX hydrolase
ERB44_RS07270	COG0406	alpha-ribazole phosphatase activity
ERB44_RS07275	COG0456	acetyltransferase
ERB44_RS07285	COG3485	protocatechuate 3,4-dioxygenase
ERB44_RS07315	COG2197	response regulator
ERB44_RS07320	COG0436	Aminotransferase
ERB44_RS07330	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ERB44_RS07340	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ERB44_RS07345	COG0081	regulation of translation
ERB44_RS07350	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ERB44_RS07355	COG0222	ribosome binding
ERB44_RS07360	COG0085	RNA polymerase activity
ERB44_RS07365	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ERB44_RS07370	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ERB44_RS07375	COG0049	tRNA binding
ERB44_RS07380	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ERB44_RS07385	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ERB44_RS07395	COG0051	transcription antitermination factor activity, RNA binding
ERB44_RS07400	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ERB44_RS07405	COG0088	Forms part of the polypeptide exit tunnel
ERB44_RS07410	COG0089	rRNA binding
ERB44_RS07415	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ERB44_RS07420	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ERB44_RS07425	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ERB44_RS07430	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ERB44_RS07435	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ERB44_RS07440	COG0255	Belongs to the universal ribosomal protein uL29 family
ERB44_RS07445	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ERB44_RS07450	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ERB44_RS07455	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ERB44_RS07460	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ERB44_RS07465	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ERB44_RS07470	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ERB44_RS07485	COG1841	ribosomal large subunit assembly
ERB44_RS07490	COG0200	Binds to the 23S rRNA
ERB44_RS07500	COG0563	adenylate kinase activity
ERB44_RS07510	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ERB44_RS07515	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ERB44_RS07520	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ERB44_RS07525	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ERB44_RS07530	COG0202	RNA polymerase activity
ERB44_RS07535	COG0203	ribosomal protein L17
ERB44_RS07540	COG0101	tRNA pseudouridine synthase activity
ERB44_RS07545	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ERB44_RS07550	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ERB44_RS07565	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ERB44_RS07575	COG1970	mechanosensitive ion channel activity
ERB44_RS07585	COG1072	(Pantothenic acid kinase))
ERB44_RS07595	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ERB44_RS07610	COG0736	holo-[acyl-carrier-protein] synthase activity
ERB44_RS07620	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ERB44_RS07625	COG0802	atpase or kinase
ERB44_RS07635	COG0456	acetyltransferase
ERB44_RS07640	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ERB44_RS07705	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ERB44_RS07710	COG0459	protein refolding
ERB44_RS07715	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ERB44_RS07720	COG1301	dicarboxylic acid transport
ERB44_RS07745	COG0519	Catalyzes the synthesis of GMP from XMP
ERB44_RS07745	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ERB44_RS07785	COG1051	belongs to the nudix hydrolase family
ERB44_RS07800	COG2326	polyphosphate kinase activity
ERB44_RS07805	COG0693	protein deglycase activity
ERB44_RS07810	COG1722	exodeoxyribonuclease VII activity
ERB44_RS07815	COG1570	exodeoxyribonuclease VII activity
ERB44_RS07825	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ERB44_RS07830	COG0471	metal ion transport
ERB44_RS07835	COG1322	Protein conserved in bacteria
ERB44_RS07850	COG2197	response regulator
ERB44_RS07855	COG4585	Histidine kinase
ERB44_RS07865	COG1131	(ABC) transporter
ERB44_RS07880	COG0012	GTP binding
ERB44_RS07955	COG4115	mRNA cleavage
ERB44_RS07995	COG1752	Esterase of the alpha-beta hydrolase superfamily
ERB44_RS08000	COG0488	(ABC) transporter
ERB44_RS08010	COG2130	NADP-dependent
ERB44_RS08015	COG2267	carboxylic ester hydrolase activity
ERB44_RS08025	COG1764	response to oxidative stress
ERB44_RS08045	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ERB44_RS08050	COG3268	Saccharopine dehydrogenase
ERB44_RS08075	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ERB44_RS08080	COG0477	Major facilitator Superfamily
ERB44_RS08090	COG0477	Major facilitator Superfamily
ERB44_RS08100	COG1174	glycine betaine transport
ERB44_RS08110	COG1174	glycine betaine transport
ERB44_RS08115	COG1732	Glycine betaine
ERB44_RS08125	COG1104	cysteine desulfurase activity
ERB44_RS08135	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ERB44_RS08145	COG0596	Alpha beta hydrolase
ERB44_RS08150	COG2354	Protein conserved in bacteria
ERB44_RS08155	COG1528	Iron-storage protein
ERB44_RS08180	COG0428	transporter
ERB44_RS08190	COG4166	transmembrane transport
ERB44_RS08210	COG1217	gtp-binding protein TYPA
ERB44_RS08240	COG2171	N-acyltransferase activity
ERB44_RS08250	COG0765	amino acid transport
ERB44_RS08255	COG0765	amino acid transport
ERB44_RS08260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ERB44_RS08265	COG1126	abc transporter atp-binding protein
ERB44_RS08270	COG1611	Belongs to the LOG family
ERB44_RS08310	COG2239	Acts as a magnesium transporter
ERB44_RS08320	COG0469	pyruvate kinase activity
ERB44_RS08325	COG0006	proline dipeptidase activity
ERB44_RS08330	COG0613	PHP domain protein
ERB44_RS08355	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ERB44_RS08360	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ERB44_RS08370	COG3253	May function as heme-dependent peroxidase
ERB44_RS08375	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ERB44_RS08380	COG0181	hydroxymethylbilane synthase activity
ERB44_RS08405	COG0113	porphobilinogen synthase activity
ERB44_RS08410	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ERB44_RS08485	COG1842	Phage shock protein A
ERB44_RS08500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ERB44_RS08505	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ERB44_RS08515	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ERB44_RS08520	COG0484	heat shock protein binding
ERB44_RS08530	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ERB44_RS08535	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ERB44_RS08540	COG0569	domain protein
ERB44_RS08555	COG0482	sulfurtransferase activity
ERB44_RS08590	COG5401	PFAM Sporulation and spore germination
ERB44_RS08600	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ERB44_RS08605	COG0653	protein targeting
ERB44_RS08660	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ERB44_RS08665	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ERB44_RS08670	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ERB44_RS08675	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ERB44_RS08690	COG0494	nUDIX hydrolase
ERB44_RS08700	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ERB44_RS08715	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ERB44_RS08720	COG0072	phenylalanine-tRNA ligase activity
ERB44_RS08720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ERB44_RS08745	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ERB44_RS08755	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ERB44_RS08760	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ERB44_RS08765	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ERB44_RS08770	COG1438	arginine binding
ERB44_RS08780	COG0137	argininosuccinate synthase activity
ERB44_RS08785	COG0165	Argininosuccinate lyase
ERB44_RS08795	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ERB44_RS08830	COG0647	UMP catabolic process
ERB44_RS08840	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ERB44_RS08845	COG0497	DNA recombination
ERB44_RS08850	COG0494	nUDIX hydrolase
ERB44_RS08860	COG0504	CTP synthase activity
ERB44_RS08875	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ERB44_RS08880	COG2079	MmgE PrpD family protein
ERB44_RS08895	COG4565	transcriptional regulatory protein
ERB44_RS08900	COG3290	protein histidine kinase activity
ERB44_RS08905	COG1301	dicarboxylic acid transport
ERB44_RS08920	COG0287	Prephenate dehydrogenase
ERB44_RS08925	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ERB44_RS08930	COG1160	GTP binding
ERB44_RS08995	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ERB44_RS09005	COG0509	glycine decarboxylation via glycine cleavage system
ERB44_RS09030	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ERB44_RS09040	COG1022	Amp-dependent synthetase and ligase
ERB44_RS09055	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ERB44_RS09065	COG1705	Flagellar rod assembly protein muramidase FlgJ
ERB44_RS09065	COG1388	LysM domain
ERB44_RS09075	COG0142	geranyltranstransferase activity
ERB44_RS09080	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ERB44_RS09090	COG2001	Belongs to the MraZ family
ERB44_RS09095	COG0275	rRNA processing
ERB44_RS09105	COG0768	penicillin binding
ERB44_RS09120	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ERB44_RS09125	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ERB44_RS09135	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ERB44_RS09140	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ERB44_RS09150	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ERB44_RS09155	COG1496	oxidoreductase activity
ERB44_RS09165	COG1799	cell septum assembly
ERB44_RS09180	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ERB44_RS09190	COG0587	DNA-directed DNA polymerase activity
ERB44_RS09195	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ERB44_RS09215	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ERB44_RS09225	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ERB44_RS09230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ERB44_RS09235	COG0174	glutamine synthetase
ERB44_RS09250	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ERB44_RS09255	COG0321	lipoyl(octanoyl) transferase activity
ERB44_RS09260	COG2815	serine threonine protein kinase
ERB44_RS09260	COG0515	serine threonine protein kinase
ERB44_RS09270	COG0508	dehydrogenase complex catalyzes the overall conversion of
ERB44_RS09275	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ERB44_RS09280	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ERB44_RS09295	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ERB44_RS09305	COG0187	DNA topoisomerase II activity
ERB44_RS09310	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ERB44_RS09315	COG0318	PFAM AMP-dependent synthetase and ligase
ERB44_RS09320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ERB44_RS09325	COG1271	oxidase subunit
ERB44_RS09340	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ERB44_RS09375	COG0756	dUTP diphosphatase activity
ERB44_RS09400	COG0569	domain protein
ERB44_RS09405	COG0531	amino acid
ERB44_RS09410	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ERB44_RS09415	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ERB44_RS09420	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ERB44_RS09430	COG0667	Aldo Keto reductase
ERB44_RS09450	COG1250	3-hydroxyacyl-CoA dehydrogenase
ERB44_RS09450	COG1024	Enoyl-CoA hydratase
ERB44_RS09455	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ERB44_RS09465	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ERB44_RS09480	COG0217	transcriptional regulatory protein
ERB44_RS09485	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ERB44_RS09490	COG0632	four-way junction helicase activity
ERB44_RS09495	COG2255	four-way junction helicase activity
ERB44_RS09510	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ERB44_RS09515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ERB44_RS09525	COG1196	nuclear chromosome segregation
ERB44_RS09530	COG0124	histidyl-tRNA synthetase
ERB44_RS09540	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ERB44_RS09545	COG1490	D-aminoacyl-tRNA deacylase activity
ERB44_RS09560	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ERB44_RS09565	COG1196	nuclear chromosome segregation
ERB44_RS09580	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ERB44_RS09595	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ERB44_RS09600	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ERB44_RS09605	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ERB44_RS09610	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ERB44_RS09615	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ERB44_RS09620	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ERB44_RS09625	COG0540	Belongs to the ATCase OTCase family
ERB44_RS09630	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ERB44_RS09640	COG0505	Belongs to the CarA family
ERB44_RS09645	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ERB44_RS09650	COG0284	orotidine-5'-phosphate decarboxylase activity
ERB44_RS09660	COG0194	GDP metabolic process
ERB44_RS09665	COG1758	RNA polymerase activity
ERB44_RS09675	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ERB44_RS09690	COG3949	Membrane
ERB44_RS09695	COG0495	leucyl-tRNA aminoacylation
ERB44_RS09700	COG1307	EDD domain protein, DegV family
ERB44_RS09720	COG0268	Binds directly to 16S ribosomal RNA
ERB44_RS09730	COG0481	GTPase activity
ERB44_RS09750	COG1420	regulation of RNA biosynthetic process
ERB44_RS09755	COG0484	heat shock protein binding
ERB44_RS09770	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ERB44_RS09780	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ERB44_RS09785	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ERB44_RS09790	COG1381	Involved in DNA repair and RecF pathway recombination
ERB44_RS09795	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ERB44_RS09805	COG0167	dihydroorotate dehydrogenase activity
ERB44_RS09825	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ERB44_RS09830	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ERB44_RS09860	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ERB44_RS09865	COG0723	plastoquinol--plastocyanin reductase activity
ERB44_RS09870	COG2010	Cytochrome c
ERB44_RS09875	COG1845	cytochrome c oxidase, subunit III
ERB44_RS09880	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ERB44_RS09915	COG0446	pyridine nucleotide-disulphide oxidoreductase
ERB44_RS09915	COG1902	pentaerythritol trinitrate reductase activity
ERB44_RS09935	COG1216	Glycosyl transferase, family 2
ERB44_RS09950	COG0805	protein transport
ERB44_RS09955	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ERB44_RS09975	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ERB44_RS10000	COG4122	O-methyltransferase activity
ERB44_RS10005	COG1222	aaa ATPase
ERB44_RS10030	COG0215	cysteine-tRNA ligase activity
ERB44_RS10035	COG1968	undecaprenyl-diphosphatase activity
ERB44_RS10050	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ERB44_RS10090	COG0297	glycogen (starch) synthase activity
ERB44_RS10095	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ERB44_RS10115	COG0254	rRNA binding
ERB44_RS10120	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ERB44_RS10130	COG1119	ATPase activity
ERB44_RS10135	COG0560	Phosphoserine phosphatase
ERB44_RS10135	COG3830	Belongs to the UPF0237 family
ERB44_RS10140	COG1028	Short-chain dehydrogenase reductase Sdr
ERB44_RS10145	COG1028	Short-chain dehydrogenase reductase Sdr
ERB44_RS10165	COG0488	(ABC) transporter
ERB44_RS10180	COG0396	ATPase activity
ERB44_RS10200	COG1131	(ABC) transporter
ERB44_RS10215	COG0109	protoheme IX farnesyltransferase activity
ERB44_RS10225	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ERB44_RS10230	COG0166	Belongs to the GPI family
ERB44_RS10250	COG0149	triose-phosphate isomerase activity
ERB44_RS10255	COG0126	phosphoglycerate kinase activity
ERB44_RS10260	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ERB44_RS10265	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ERB44_RS10270	COG1481	regulation of sporulation
ERB44_RS10275	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ERB44_RS10280	COG1660	Displays ATPase and GTPase activities
ERB44_RS10285	COG0322	excinuclease ABC activity
ERB44_RS10305	COG4106	trans-aconitate 2-methyltransferase activity
ERB44_RS10340	COG0556	nucleotide-excision repair
ERB44_RS10345	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ERB44_RS10345	COG0237	dephospho-CoA kinase activity
ERB44_RS10350	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ERB44_RS10355	COG1739	Uncharacterized protein family UPF0029
ERB44_RS10360	COG2813	Specifically methylates the guanine in position
ERB44_RS10365	COG0539	negative regulation of cytoplasmic translation
ERB44_RS10370	COG4552	Acetyltransferase involved in intracellular survival and related
ERB44_RS10380	COG2050	protein possibly involved in aromatic compounds catabolism
ERB44_RS10395	COG1863	multisubunit Na H antiporter MnhE subunit
ERB44_RS10410	COG2111	Na H antiporter
ERB44_RS10410	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ERB44_RS10440	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ERB44_RS10455	COG1320	monovalent cation:proton antiporter activity
ERB44_RS10465	COG1863	multisubunit Na H antiporter MnhE subunit
ERB44_RS10515	COG0159	tryptophan synthase activity
ERB44_RS10520	COG0133	tryptophan synthase activity
ERB44_RS10525	COG0134	indole-3-glycerol-phosphate synthase activity
ERB44_RS10545	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ERB44_RS10550	COG0107	imidazoleglycerol-phosphate synthase activity
ERB44_RS10555	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ERB44_RS10560	COG0140	phosphoribosyl-ATP diphosphatase activity
ERB44_RS10565	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ERB44_RS10590	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ERB44_RS10600	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ERB44_RS10605	COG0242	peptide deformylase activity
ERB44_RS10655	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ERB44_RS10665	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ERB44_RS10670	COG0587	DNA-directed DNA polymerase activity
ERB44_RS10700	COG2135	peptidase activity
ERB44_RS10715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ERB44_RS10735	COG1464	Belongs to the NlpA lipoprotein family
ERB44_RS10740	COG2011	ABC-type metal ion transport system permease component
ERB44_RS10745	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ERB44_RS10755	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ERB44_RS10760	COG1780	Probably involved in ribonucleotide reductase function
ERB44_RS10765	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ERB44_RS10780	COG3328	transposase activity
ERB44_RS10815	COG0583	DNA-binding transcription factor activity
ERB44_RS10830	COG1012	belongs to the aldehyde dehydrogenase family
ERB44_RS10845	COG1309	transcriptional regulator
ERB44_RS10860	COG0673	inositol 2-dehydrogenase activity
ERB44_RS10875	COG3328	transposase activity
ERB44_RS10890	COG0464	growth
ERB44_RS10915	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ERB44_RS10925	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ERB44_RS10930	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ERB44_RS10935	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ERB44_RS10940	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ERB44_RS10945	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ERB44_RS10950	COG1530	ribonuclease E activity
ERB44_RS10960	COG0105	UTP biosynthetic process
ERB44_RS10970	COG0285	dihydrofolate synthase activity
ERB44_RS10975	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ERB44_RS10990	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ERB44_RS10990	COG1648	precorrin-2 dehydrogenase activity
ERB44_RS11000	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ERB44_RS11015	COG0175	sulfate reduction
ERB44_RS11035	COG0525	valine-tRNA ligase activity
ERB44_RS11045	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ERB44_RS11050	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ERB44_RS11055	COG0740	serine-type endopeptidase activity
ERB44_RS11060	COG0740	serine-type endopeptidase activity
ERB44_RS11065	COG0544	peptidyl-prolyl cis-trans isomerase activity
ERB44_RS11120	COG1946	Acyl-CoA thioesterase
ERB44_RS11130	COG0629	single-stranded DNA binding
ERB44_RS11160	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ERB44_RS11170	COG4974	Belongs to the 'phage' integrase family
ERB44_RS11220	COG2217	Heavy metal translocating P-type atpase
ERB44_RS11230	COG0242	peptide deformylase activity
ERB44_RS11235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ERB44_RS11255	COG3022	response to hydroperoxide
ERB44_RS11270	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ERB44_RS11275	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ERB44_RS11290	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ERB44_RS11295	COG2326	polyphosphate kinase activity
ERB44_RS11335	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ERB44_RS11350	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ERB44_RS11355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ERB44_RS11385	COG0792	nuclease activity
ERB44_RS11395	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ERB44_RS11400	COG0681	Belongs to the peptidase S26 family
ERB44_RS11405	COG0681	Belongs to the peptidase S26 family
ERB44_RS11410	COG0335	large ribosomal subunit rRNA binding
ERB44_RS11415	COG0336	Belongs to the RNA methyltransferase TrmD family
ERB44_RS11430	COG0228	four-way junction DNA binding
ERB44_RS11465	COG2814	Major facilitator Superfamily
ERB44_RS11470	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ERB44_RS11480	COG1134	teichoic acid transport
ERB44_RS11490	COG0297	glycogen (starch) synthase activity
ERB44_RS11520	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ERB44_RS11530	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ERB44_RS11550	COG1316	TRANSCRIPTIONal
ERB44_RS11555	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ERB44_RS11560	COG0571	ribonuclease III activity
ERB44_RS11565	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ERB44_RS11575	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ERB44_RS11580	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ERB44_RS11600	COG1461	Dihydroxyacetone kinase
ERB44_RS11605	COG1316	TRANSCRIPTIONal
ERB44_RS11615	COG1181	Belongs to the D-alanine--D-alanine ligase family
ERB44_RS11620	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ERB44_RS11630	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ERB44_RS11635	COG0066	3-isopropylmalate dehydratase activity
ERB44_RS11640	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ERB44_RS11650	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ERB44_RS11665	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ERB44_RS11690	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ERB44_RS11695	COG0179	Fumarylacetoacetate (FAA) hydrolase
ERB44_RS11705	COG1966	Carbon starvation protein
ERB44_RS11710	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ERB44_RS11735	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ERB44_RS11740	COG0440	acetolactate synthase activity
ERB44_RS11755	COG0129	dihydroxy-acid dehydratase activity
ERB44_RS11785	COG0579	oxidoreductase
ERB44_RS11795	COG0419	ATPase involved in DNA repair
ERB44_RS11805	COG2176	DNA-directed DNA polymerase activity
ERB44_RS11815	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ERB44_RS11820	COG1234	tRNA 3'-trailer cleavage
ERB44_RS11910	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ERB44_RS11935	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ERB44_RS11940	COG0356	it plays a direct role in the translocation of protons across the membrane
ERB44_RS11955	COG0009	L-threonylcarbamoyladenylate synthase