locus-tag	class	description
MT1254_RS00010	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MT1254_RS00020	COG0083	homoserine kinase activity
MT1254_RS00025	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MT1254_RS00030	COG0460	homoserine dehydrogenase
MT1254_RS00035	COG0019	diaminopimelate decarboxylase activity
MT1254_RS00040	COG0018	arginyl-trna synthetase
MT1254_RS00050	COG2022	thiamine diphosphate biosynthetic process
MT1254_RS00065	COG0352	thiamine-phosphate diphosphorylase activity
MT1254_RS00075	COG0352	thiamine-phosphate diphosphorylase activity
MT1254_RS00075	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MT1254_RS00075	COG0351	phosphomethylpyrimidine kinase
MT1254_RS00080	COG3949	Membrane
MT1254_RS00100	COG0577	efflux transmembrane transporter activity
MT1254_RS00100	COG1136	(ABC) transporter
MT1254_RS00105	COG0519	Catalyzes the synthesis of GMP from XMP
MT1254_RS00110	COG1012	belongs to the aldehyde dehydrogenase family
MT1254_RS00120	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MT1254_RS00125	COG1643	Atp-dependent helicase
MT1254_RS00140	COG0735	belongs to the Fur family
MT1254_RS00145	COG1121	(ABC) transporter
MT1254_RS00150	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MT1254_RS00155	COG0803	Belongs to the bacterial solute-binding protein 9 family
MT1254_RS00160	COG1253	flavin adenine dinucleotide binding
MT1254_RS00165	COG1253	flavin adenine dinucleotide binding
MT1254_RS00175	COG0508	dehydrogenase complex catalyzes the overall conversion of
MT1254_RS00175	COG0567	Dehydrogenase, E1 component
MT1254_RS00190	COG1595	DNA-templated transcription, initiation
MT1254_RS00195	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MT1254_RS00205	COG0483	inositol monophosphate 1-phosphatase activity
MT1254_RS00225	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MT1254_RS00240	COG0183	Belongs to the thiolase family
MT1254_RS00245	COG1063	alcohol dehydrogenase
MT1254_RS00250	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MT1254_RS00295	COG1674	ftsk spoiiie
MT1254_RS00315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MT1254_RS00340	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MT1254_RS00345	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MT1254_RS00350	COG0131	Imidazoleglycerol-phosphate dehydratase
MT1254_RS00355	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MT1254_RS00365	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MT1254_RS00375	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MT1254_RS00380	COG2072	flavoprotein involved in K transport
MT1254_RS00390	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MT1254_RS00395	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MT1254_RS00400	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MT1254_RS00405	COG2137	regulation of response to DNA damage stimulus
MT1254_RS00410	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MT1254_RS00425	COG1396	sequence-specific DNA binding
MT1254_RS00435	COG1546	Belongs to the CinA family
MT1254_RS00435	COG1058	Belongs to the CinA family
MT1254_RS00445	COG1674	ftsk spoiiie
MT1254_RS00450	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MT1254_RS00455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MT1254_RS00470	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MT1254_RS00475	COG0612	Peptidase, M16
MT1254_RS00480	COG1185	polyribonucleotide nucleotidyltransferase activity
MT1254_RS00485	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MT1254_RS00515	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MT1254_RS00520	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MT1254_RS00525	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MT1254_RS00550	COG0442	prolyl-tRNA aminoacylation
MT1254_RS00560	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MT1254_RS00565	COG0750	zinc metalloprotease
MT1254_RS00575	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MT1254_RS00595	COG1960	acyl-CoA dehydrogenase activity
MT1254_RS00605	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MT1254_RS00620	COG0508	dehydrogenase complex catalyzes the overall conversion of
MT1254_RS00625	COG0022	dehydrogenase e1 component
MT1254_RS00645	COG0233	cytoplasmic translational termination
MT1254_RS00650	COG0528	UMP kinase activity
MT1254_RS00655	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MT1254_RS00660	COG0052	Belongs to the universal ribosomal protein uS2 family
MT1254_RS00690	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MT1254_RS00700	COG0656	L-ascorbic acid biosynthetic process
MT1254_RS00710	COG1028	Short-chain dehydrogenase reductase Sdr
MT1254_RS00720	COG2267	carboxylic ester hydrolase activity
MT1254_RS00740	COG3328	transposase activity
MT1254_RS00755	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MT1254_RS00760	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MT1254_RS00765	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MT1254_RS00790	COG2801	Transposase and inactivated derivatives
MT1254_RS00800	COG3328	transposase activity
MT1254_RS00825	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MT1254_RS00840	COG0785	Cytochrome C biogenesis protein
MT1254_RS00875	COG3328	transposase activity
MT1254_RS00890	COG4916	TIR domain
MT1254_RS00900	COG0322	excinuclease ABC activity
MT1254_RS00915	COG3328	transposase activity
MT1254_RS01025	COG0358	DNA primase activity
MT1254_RS01065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MT1254_RS01085	COG0423	glycine-tRNA ligase activity
MT1254_RS01105	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MT1254_RS01110	COG2873	o-acetylhomoserine
MT1254_RS01135	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MT1254_RS01140	COG0154	amidase activity
MT1254_RS01145	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MT1254_RS01160	COG0483	inositol monophosphate 1-phosphatase activity
MT1254_RS01165	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MT1254_RS01170	COG0631	protein serine/threonine phosphatase activity
MT1254_RS01190	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MT1254_RS01205	COG0424	maF-like protein
MT1254_RS01210	COG4770	biotin carboxylase activity
MT1254_RS01215	COG0477	Major facilitator Superfamily
MT1254_RS01230	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MT1254_RS01235	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MT1254_RS01280	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MT1254_RS01285	COG0193	aminoacyl-tRNA hydrolase activity
MT1254_RS01290	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MT1254_RS01300	COG0489	protein tyrosine kinase activity
MT1254_RS01325	COG3328	transposase activity
MT1254_RS01350	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MT1254_RS01355	COG1216	Glycosyl transferase, family 2
MT1254_RS01375	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MT1254_RS01395	COG0438	transferase activity, transferring glycosyl groups
MT1254_RS01405	COG2089	acid synthase
MT1254_RS01410	COG1083	cytidylyl-transferase
MT1254_RS01460	COG2826	transposase and inactivated derivatives, IS30 family
MT1254_RS01465	COG3328	transposase activity
MT1254_RS01500	COG0681	Belongs to the peptidase S26 family
MT1254_RS01520	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MT1254_RS01535	COG0488	(ABC) transporter
MT1254_RS01540	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MT1254_RS01545	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MT1254_RS01555	COG0084	hydrolase, TatD family'
MT1254_RS01590	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MT1254_RS01595	COG0004	ammonium transporteR
MT1254_RS01615	COG0583	DNA-binding transcription factor activity
MT1254_RS01665	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MT1254_RS01670	COG1316	TRANSCRIPTIONal
MT1254_RS01675	COG1482	cell wall glycoprotein biosynthetic process
MT1254_RS01695	COG0114	fumarate hydratase activity
MT1254_RS01705	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MT1254_RS01715	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MT1254_RS01730	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MT1254_RS01740	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MT1254_RS01750	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MT1254_RS01790	COG0148	phosphopyruvate hydratase activity
MT1254_RS01820	COG1079	Belongs to the binding-protein-dependent transport system permease family
MT1254_RS01825	COG4603	Belongs to the binding-protein-dependent transport system permease family
MT1254_RS01830	COG3845	ABC transporter
MT1254_RS01835	COG1744	ABC transporter substrate-binding protein PnrA-like
MT1254_RS01840	COG1473	amidohydrolase
MT1254_RS01840	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MT1254_RS01850	COG2009	succinate dehydrogenase
MT1254_RS01865	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MT1254_RS01890	COG1136	(ABC) transporter
MT1254_RS01895	COG0180	Tryptophanyl-tRNA synthetase
MT1254_RS01920	COG1131	(ABC) transporter
MT1254_RS01925	COG4716	Myosin-crossreactive antigen
MT1254_RS01935	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MT1254_RS01955	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MT1254_RS01985	COG1643	Atp-dependent helicase
MT1254_RS01990	COG2066	Belongs to the glutaminase family
MT1254_RS01995	COG1090	epimerase
MT1254_RS02000	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MT1254_RS02000	COG2169	Transcriptional regulator
MT1254_RS02005	COG2838	Isocitrate dehydrogenase
MT1254_RS02015	COG2239	Acts as a magnesium transporter
MT1254_RS02020	COG0138	bifunctional purine biosynthesis protein purh
MT1254_RS02025	COG0477	Major facilitator Superfamily
MT1254_RS02050	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MT1254_RS02090	COG0028	Belongs to the TPP enzyme family
MT1254_RS02150	COG2197	response regulator
MT1254_RS02160	COG0045	succinate-CoA ligase (ADP-forming) activity
MT1254_RS02180	COG1132	(ABC) transporter
MT1254_RS02205	COG1278	Cold shock
MT1254_RS02220	COG0745	RESPONSE REGULATOR receiver
MT1254_RS02225	COG2205	protein histidine kinase activity
MT1254_RS02240	COG0459	protein refolding
MT1254_RS02255	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MT1254_RS02270	COG1404	Belongs to the peptidase S8 family
MT1254_RS02310	COG0179	Fumarylacetoacetate (FAA) hydrolase
MT1254_RS02325	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MT1254_RS02360	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MT1254_RS02365	COG0366	Alpha amylase catalytic
MT1254_RS02375	COG4120	Belongs to the binding-protein-dependent transport system permease family
MT1254_RS02385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MT1254_RS02390	COG0215	cysteine-tRNA ligase activity
MT1254_RS02395	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MT1254_RS02395	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MT1254_RS02415	COG5002	protein histidine kinase activity
MT1254_RS02425	COG0588	phosphoglycerate mutase activity
MT1254_RS02440	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MT1254_RS02445	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MT1254_RS02475	COG0737	Belongs to the 5'-nucleotidase family
MT1254_RS02510	COG2814	Major facilitator Superfamily
MT1254_RS02530	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MT1254_RS02530	COG1017	nitric oxide dioxygenase activity
MT1254_RS02540	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
MT1254_RS02545	COG0829	nickel cation binding
MT1254_RS02550	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MT1254_RS02555	COG0830	nickel cation binding
MT1254_RS02560	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
MT1254_RS02565	COG0804	urea catabolic process
MT1254_RS02570	COG0832	Belongs to the urease beta subunit family
MT1254_RS02575	COG0831	urea catabolic process
MT1254_RS02580	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
MT1254_RS02590	COG2062	phosphohistidine phosphatase, SixA
MT1254_RS02595	COG0745	RESPONSE REGULATOR receiver
MT1254_RS02600	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MT1254_RS02620	COG0657	acetylesterase activity
MT1254_RS02625	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MT1254_RS02630	COG1201	RNA secondary structure unwinding
MT1254_RS02645	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MT1254_RS02655	COG0564	pseudouridine synthase activity
MT1254_RS02675	COG1902	pentaerythritol trinitrate reductase activity
MT1254_RS02705	COG0343	queuine tRNA-ribosyltransferase activity
MT1254_RS02715	COG3328	transposase activity
MT1254_RS02725	COG1960	acyl-CoA dehydrogenase activity
MT1254_RS02750	COG0351	phosphomethylpyrimidine kinase
MT1254_RS02765	COG4585	Histidine kinase
MT1254_RS02770	COG2197	response regulator
MT1254_RS02780	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MT1254_RS02785	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MT1254_RS02785	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MT1254_RS02790	COG1914	H( )-stimulated, divalent metal cation uptake system
MT1254_RS02795	COG1917	Cupin 2, conserved barrel domain protein
MT1254_RS02810	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MT1254_RS02835	COG1024	Enoyl-CoA hydratase
MT1254_RS02840	COG1024	Enoyl-CoA hydratase
MT1254_RS02855	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
MT1254_RS02860	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MT1254_RS02875	COG1760	l-serine dehydratase
MT1254_RS02900	COG0028	Belongs to the TPP enzyme family
MT1254_RS02905	COG1115	amino acid carrier protein
MT1254_RS02920	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MT1254_RS02925	COG0778	Nitroreductase
MT1254_RS02935	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MT1254_RS02955	COG1404	Belongs to the peptidase S8 family
MT1254_RS02965	COG0596	Alpha beta hydrolase
MT1254_RS02980	COG1476	TRANSCRIPTIONal
MT1254_RS02985	COG3012	SEC-C Motif Domain Protein
MT1254_RS02995	COG0047	phosphoribosylformylglycinamidine synthase activity
MT1254_RS03025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MT1254_RS03035	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MT1254_RS03055	COG5006	permease, DMT superfamily
MT1254_RS03080	COG1832	CoA-binding protein
MT1254_RS03085	COG0010	Belongs to the arginase family
MT1254_RS03095	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MT1254_RS03105	COG2986	histidine ammonia-lyase
MT1254_RS03110	COG1228	amidohydrolase
MT1254_RS03115	COG3314	Sporulation integral membrane protein YlbJ
MT1254_RS03120	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MT1254_RS03135	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MT1254_RS03145	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MT1254_RS03155	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MT1254_RS03160	COG3328	transposase activity
MT1254_RS03175	COG2031	fatty acid transporter
MT1254_RS03180	COG1435	thymidine kinase activity
MT1254_RS03195	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MT1254_RS03205	COG1476	TRANSCRIPTIONal
MT1254_RS03210	COG0191	fructose-bisphosphate aldolase activity
MT1254_RS03235	COG0598	Magnesium transport protein CorA
MT1254_RS03240	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MT1254_RS03255	COG0708	Exodeoxyribonuclease III
MT1254_RS03265	COG0778	Nitroreductase
MT1254_RS03270	COG0366	Alpha amylase catalytic
MT1254_RS03335	COG1914	H( )-stimulated, divalent metal cation uptake system
MT1254_RS03340	COG0280	phosphate acetyltransferase
MT1254_RS03340	COG0857	belongs to the CobB CobQ family
MT1254_RS03345	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MT1254_RS03355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MT1254_RS03360	COG0601	transmembrane transport
MT1254_RS03365	COG0747	negative chemotaxis
MT1254_RS03375	COG2733	membrane
MT1254_RS03410	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MT1254_RS03450	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MT1254_RS03460	COG3237	CsbD-like
MT1254_RS03480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MT1254_RS03485	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MT1254_RS03495	COG1846	Transcriptional regulator
MT1254_RS03500	COG3590	peptidase
MT1254_RS03510	COG2094	Belongs to the DNA glycosylase MPG family
MT1254_RS03515	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MT1254_RS03535	COG0584	glycerophosphoryl diester phosphodiesterase
MT1254_RS03540	COG0823	Involved in the tonB-independent uptake of proteins
MT1254_RS03540	COG1506	peptidase
MT1254_RS03550	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MT1254_RS03565	COG3402	PFAM membrane-flanked domain
MT1254_RS03580	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MT1254_RS03590	COG0302	gtp cyclohydrolase
MT1254_RS03610	COG0037	tRNA processing
MT1254_RS03620	COG2027	D-alanyl-D-alanine carboxypeptidase
MT1254_RS03625	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MT1254_RS03640	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MT1254_RS03690	COG1012	belongs to the aldehyde dehydrogenase family
MT1254_RS03695	COG0584	glycerophosphoryl diester phosphodiesterase
MT1254_RS03700	COG1522	sequence-specific DNA binding
MT1254_RS03710	COG4221	oxidoreductase activity
MT1254_RS03720	COG0833	amino acid
MT1254_RS03735	COG0561	phosphatase activity
MT1254_RS03740	COG0039	L-malate dehydrogenase activity
MT1254_RS03750	COG2233	PERMEase
MT1254_RS03770	COG2353	YceI-like domain
MT1254_RS03775	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MT1254_RS03800	COG0589	response to stress
MT1254_RS03810	COG1131	(ABC) transporter
MT1254_RS03810	COG1716	ATPase activity
MT1254_RS03810	COG0842	Transport permease protein
MT1254_RS03815	COG1716	ATPase activity
MT1254_RS03835	COG0515	serine threonine protein kinase
MT1254_RS03840	COG0515	serine threonine protein kinase
MT1254_RS03870	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MT1254_RS03895	COG3266	domain, Protein
MT1254_RS03900	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MT1254_RS03905	COG0187	DNA topoisomerase II activity
MT1254_RS03910	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
MT1254_RS03915	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MT1254_RS03925	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MT1254_RS03930	COG0230	Belongs to the bacterial ribosomal protein bL34 family
MT1254_RS03935	COG0594	ribonuclease P activity
MT1254_RS03940	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MT1254_RS03955	COG0357	Ribosomal RNA small subunit methyltransferase G
MT1254_RS03960	COG1192	Involved in chromosome partitioning
MT1254_RS03975	COG0492	ferredoxin-NADP+ reductase activity
MT1254_RS03995	COG0617	tRNA 3'-terminal CCA addition
MT1254_RS04015	COG1260	myo-inositol-1-phosphate synthase
MT1254_RS04030	COG1362	aminopeptidase activity
MT1254_RS04035	COG0360	Binds together with S18 to 16S ribosomal RNA
MT1254_RS04045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MT1254_RS04050	COG0359	binds to the 23S rRNA
MT1254_RS04075	COG0189	ligase activity
MT1254_RS04075	COG4067	protein conserved in archaea
MT1254_RS04080	COG0189	ligase activity
MT1254_RS04080	COG0569	domain protein
MT1254_RS04095	COG0305	Participates in initiation and elongation during chromosome replication
MT1254_RS04115	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
MT1254_RS04150	COG2318	DinB family
MT1254_RS04165	COG3177	Filamentation induced by cAMP protein fic
MT1254_RS04175	COG1380	Effector of murein hydrolase LrgA
MT1254_RS04195	COG0318	PFAM AMP-dependent synthetase and ligase
MT1254_RS04200	COG1063	alcohol dehydrogenase
MT1254_RS04205	COG0789	Transcriptional regulator
MT1254_RS04210	COG1115	amino acid carrier protein
MT1254_RS04220	COG0626	cystathionine gamma-synthase activity
MT1254_RS04225	COG1574	metal-dependent hydrolase with the TIM-barrel fold
MT1254_RS04230	COG1028	Short-chain dehydrogenase reductase Sdr
MT1254_RS04240	COG0133	tryptophan synthase activity
MT1254_RS04255	COG3328	transposase activity
MT1254_RS04300	COG2814	Major facilitator Superfamily
MT1254_RS04365	COG0739	heme binding
MT1254_RS04380	COG0488	(ABC) transporter
MT1254_RS04385	COG1511	domain protein
MT1254_RS04385	COG1511	domain protein
MT1254_RS04420	COG2357	RelA SpoT domain protein
MT1254_RS04430	COG0277	FAD linked oxidase domain protein
MT1254_RS04445	COG2066	Belongs to the glutaminase family
MT1254_RS04455	COG0702	epimerase
MT1254_RS04465	COG1120	ATPase activity
MT1254_RS04470	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MT1254_RS04475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MT1254_RS04485	COG2226	methyltransferase
MT1254_RS04490	COG0745	RESPONSE REGULATOR receiver
MT1254_RS04500	COG2205	protein histidine kinase activity
MT1254_RS04505	COG0583	DNA-binding transcription factor activity
MT1254_RS04520	COG1132	(ABC) transporter
MT1254_RS04530	COG0385	Bile acid
MT1254_RS04540	COG4591	ABC-type transport system involved in lipoprotein release permease component
MT1254_RS04545	COG1136	(ABC) transporter
MT1254_RS04545	COG0577	efflux transmembrane transporter activity
MT1254_RS04550	COG1309	transcriptional regulator
MT1254_RS04560	COG2197	response regulator
MT1254_RS04565	COG4585	Histidine kinase
MT1254_RS04570	COG4585	Histidine kinase
MT1254_RS04585	COG4585	Histidine kinase
MT1254_RS04590	COG2197	response regulator
MT1254_RS04655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MT1254_RS04655	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MT1254_RS04660	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MT1254_RS04670	COG1937	Protein conserved in bacteria
MT1254_RS04705	COG1136	(ABC) transporter
MT1254_RS04720	COG0659	secondary active sulfate transmembrane transporter activity
MT1254_RS04750	COG0039	L-malate dehydrogenase activity
MT1254_RS04760	COG0028	Belongs to the TPP enzyme family
MT1254_RS04780	COG1012	belongs to the aldehyde dehydrogenase family
MT1254_RS04820	COG2608	mercury ion transmembrane transporter activity
MT1254_RS04825	COG1937	Protein conserved in bacteria
MT1254_RS04830	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MT1254_RS04835	COG1169	isochorismate synthase
MT1254_RS04850	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MT1254_RS04860	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MT1254_RS04865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MT1254_RS04880	COG0142	geranyltranstransferase activity
MT1254_RS04890	COG1233	COG1233 Phytoene dehydrogenase and related
MT1254_RS04925	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MT1254_RS04930	COG0436	Aminotransferase
MT1254_RS04980	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MT1254_RS05000	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MT1254_RS05010	COG3311	Transcriptional regulator
MT1254_RS05015	COG1569	PIN domain
MT1254_RS05035	COG0667	Aldo Keto reductase
MT1254_RS05040	COG0789	Transcriptional regulator
MT1254_RS05055	COG3328	transposase activity
MT1254_RS05075	COG0446	pyridine nucleotide-disulphide oxidoreductase
MT1254_RS05080	COG0789	Transcriptional regulator
MT1254_RS05115	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MT1254_RS05120	COG0492	ferredoxin-NADP+ reductase activity
MT1254_RS05125	COG0492	ferredoxin-NADP+ reductase activity
MT1254_RS05130	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MT1254_RS05135	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MT1254_RS05140	COG0798	PFAM Bile acid sodium symporter
MT1254_RS05150	COG2072	flavoprotein involved in K transport
MT1254_RS05155	COG3328	transposase activity
MT1254_RS05165	COG3328	transposase activity
MT1254_RS05190	COG3328	transposase activity
MT1254_RS05200	COG0456	acetyltransferase
MT1254_RS05210	COG0697	spore germination
MT1254_RS05230	COG1136	(ABC) transporter
MT1254_RS05245	COG1028	Short-chain dehydrogenase reductase Sdr
MT1254_RS05280	COG1280	lysine exporter protein (LysE YggA)
MT1254_RS05285	COG0789	Transcriptional regulator
MT1254_RS05335	COG1309	transcriptional regulator
MT1254_RS05420	COG1268	BioY protein
MT1254_RS05425	COG1122	ATPase activity
MT1254_RS05435	COG1607	acyl-coa hydrolase
MT1254_RS05450	COG2318	DinB family
MT1254_RS05455	COG0318	PFAM AMP-dependent synthetase and ligase
MT1254_RS05495	COG1074	ATP-dependent DNA helicase activity
MT1254_RS05500	COG1074	ATP-dependent DNA helicase activity
MT1254_RS05525	COG4868	Belongs to the UPF0371 family
MT1254_RS05530	COG2860	membrane
MT1254_RS05535	COG2860	membrane
MT1254_RS05555	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MT1254_RS05575	COG1309	transcriptional regulator
MT1254_RS05585	COG1250	3-hydroxyacyl-CoA dehydrogenase
MT1254_RS05590	COG2030	dehydratase
MT1254_RS05590	COG1012	belongs to the aldehyde dehydrogenase family
MT1254_RS05600	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MT1254_RS05610	COG2315	Protein conserved in bacteria
MT1254_RS05620	COG1024	Enoyl-CoA hydratase
MT1254_RS05630	COG0477	Major facilitator Superfamily
MT1254_RS05640	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MT1254_RS05645	COG2151	metal-sulfur cluster biosynthetic enzyme
MT1254_RS05650	COG3396	Phenylacetate-CoA oxygenase
MT1254_RS05655	COG3460	Phenylacetate-CoA oxygenase
MT1254_RS05660	COG3396	Phenylacetate-CoA oxygenase
MT1254_RS05685	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MT1254_RS05725	COG3971	2-oxopent-4-enoate hydratase activity
MT1254_RS05750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MT1254_RS05770	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MT1254_RS05775	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MT1254_RS05780	COG0686	Belongs to the AlaDH PNT family
MT1254_RS05795	COG2186	Transcriptional regulator
MT1254_RS05805	COG1620	l-lactate permease
MT1254_RS05810	COG0247	lactate metabolic process
MT1254_RS05815	COG1139	Iron-sulfur cluster binding protein
MT1254_RS05820	COG1556	Lactate utilization protein
MT1254_RS05885	COG3540	Alkaline phosphatase
MT1254_RS05935	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
MT1254_RS05940	COG0732	type I restriction modification DNA specificity domain
MT1254_RS05975	COG1024	Enoyl-CoA hydratase
MT1254_RS05990	COG0183	Belongs to the thiolase family
MT1254_RS06020	COG3842	ATPase activity
MT1254_RS06025	COG4149	molybdate abc transporter
MT1254_RS06035	COG0628	permease
MT1254_RS06045	COG1012	belongs to the aldehyde dehydrogenase family
MT1254_RS06055	COG0069	glutamate synthase activity
MT1254_RS06065	COG1278	Cold shock
MT1254_RS06090	COG1136	(ABC) transporter
MT1254_RS06100	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MT1254_RS06105	COG3264	Mechanosensitive ion channel
MT1254_RS06105	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
MT1254_RS06115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MT1254_RS06120	COG0435	Glutathione S-transferase
MT1254_RS06125	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
MT1254_RS06135	COG4770	biotin carboxylase activity
MT1254_RS06145	COG4336	lyase activity
MT1254_RS06150	COG1914	H( )-stimulated, divalent metal cation uptake system
MT1254_RS06160	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MT1254_RS06165	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MT1254_RS06170	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MT1254_RS06175	COG0776	regulation of translation
MT1254_RS06195	COG2847	Copper chaperone PCu(A)C
MT1254_RS06200	COG2837	iron assimilation
MT1254_RS06205	COG3336	cytochrome c oxidase
MT1254_RS06230	COG1748	Saccharopine dehydrogenase
MT1254_RS06235	COG0679	Auxin Efflux Carrier
MT1254_RS06250	COG0475	glutathione-regulated potassium exporter activity
MT1254_RS06265	COG0717	Belongs to the dCTP deaminase family
MT1254_RS06275	COG2111	Na H antiporter
MT1254_RS06275	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MT1254_RS06285	COG0651	ATP synthesis coupled electron transport
MT1254_RS06300	COG1320	monovalent cation:proton antiporter activity
MT1254_RS06330	COG2409	Drug exporters of the RND superfamily
MT1254_RS06335	COG0783	Belongs to the Dps family
MT1254_RS06340	COG0443	Heat shock 70 kDa protein
MT1254_RS06345	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MT1254_RS06350	COG0484	heat shock protein binding
MT1254_RS06355	COG0789	Transcriptional regulator
MT1254_RS06365	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MT1254_RS06390	COG0765	amino acid transport
MT1254_RS06395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MT1254_RS06410	COG0542	response to heat
MT1254_RS06425	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MT1254_RS06435	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MT1254_RS06485	COG0151	Belongs to the GarS family
MT1254_RS06490	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MT1254_RS06500	COG1132	(ABC) transporter
MT1254_RS06505	COG1132	(ABC) transporter
MT1254_RS06510	COG1408	metallophosphoesterase
MT1254_RS06515	COG4499	WXG100 protein secretion system (Wss), protein YukC
MT1254_RS06515	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MT1254_RS06530	COG3588	fructose-bisphosphate aldolase
MT1254_RS06545	COG2217	Heavy metal translocating P-type atpase
MT1254_RS06560	COG0745	RESPONSE REGULATOR receiver
MT1254_RS06570	COG2132	Multicopper oxidase
MT1254_RS06605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MT1254_RS06610	COG0733	neurotransmitter:sodium symporter activity
MT1254_RS06625	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MT1254_RS06630	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MT1254_RS06635	COG2072	flavoprotein involved in K transport
MT1254_RS06670	COG1111	helicase
MT1254_RS06670	COG1205	dead DEAH box helicase
MT1254_RS06685	COG2890	protein-(glutamine-N5) methyltransferase activity
MT1254_RS06705	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MT1254_RS06705	COG1754	DNA topoisomerase type I activity
MT1254_RS06710	COG0248	Ppx GppA phosphatase
MT1254_RS06725	COG0569	domain protein
MT1254_RS06730	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MT1254_RS06735	COG0123	including yeast histone deacetylase and acetoin utilization protein
MT1254_RS06755	COG0406	alpha-ribazole phosphatase activity
MT1254_RS06765	COG0785	Cytochrome C biogenesis protein
MT1254_RS06775	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MT1254_RS06805	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MT1254_RS06815	COG2252	PERMEase
MT1254_RS06835	COG0022	dehydrogenase e1 component
MT1254_RS06840	COG0508	dehydrogenase complex catalyzes the overall conversion of
MT1254_RS06865	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MT1254_RS06870	COG0644	oxidoreductase
MT1254_RS06875	COG0142	geranyltranstransferase activity
MT1254_RS06880	COG0537	adenosine 5'-monophosphoramidase activity
MT1254_RS06910	COG1666	GTP binding
MT1254_RS06920	COG0318	PFAM AMP-dependent synthetase and ligase
MT1254_RS06945	COG1228	amidohydrolase
MT1254_RS06975	COG2030	dehydratase
MT1254_RS06985	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MT1254_RS06990	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MT1254_RS07005	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MT1254_RS07015	COG0494	nUDIX hydrolase
MT1254_RS07015	COG0406	alpha-ribazole phosphatase activity
MT1254_RS07030	COG3485	protocatechuate 3,4-dioxygenase
MT1254_RS07060	COG2197	response regulator
MT1254_RS07065	COG0436	Aminotransferase
MT1254_RS07075	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MT1254_RS07085	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MT1254_RS07090	COG0081	regulation of translation
MT1254_RS07095	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MT1254_RS07100	COG0222	ribosome binding
MT1254_RS07110	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MT1254_RS07115	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MT1254_RS07120	COG0049	tRNA binding
MT1254_RS07125	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MT1254_RS07130	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MT1254_RS07140	COG0051	transcription antitermination factor activity, RNA binding
MT1254_RS07145	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MT1254_RS07150	COG0088	Forms part of the polypeptide exit tunnel
MT1254_RS07155	COG0089	rRNA binding
MT1254_RS07160	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MT1254_RS07165	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MT1254_RS07170	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MT1254_RS07175	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MT1254_RS07180	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MT1254_RS07185	COG0255	Belongs to the universal ribosomal protein uL29 family
MT1254_RS07190	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MT1254_RS07195	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MT1254_RS07200	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MT1254_RS07205	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MT1254_RS07210	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MT1254_RS07215	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MT1254_RS07230	COG1841	ribosomal large subunit assembly
MT1254_RS07235	COG0200	Binds to the 23S rRNA
MT1254_RS07245	COG0563	adenylate kinase activity
MT1254_RS07255	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MT1254_RS07260	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MT1254_RS07265	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MT1254_RS07270	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MT1254_RS07275	COG0202	RNA polymerase activity
MT1254_RS07280	COG0203	ribosomal protein L17
MT1254_RS07285	COG0101	tRNA pseudouridine synthase activity
MT1254_RS07290	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MT1254_RS07295	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MT1254_RS07310	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MT1254_RS07320	COG1970	mechanosensitive ion channel activity
MT1254_RS07330	COG1072	(Pantothenic acid kinase))
MT1254_RS07335	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MT1254_RS07340	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MT1254_RS07355	COG0736	holo-[acyl-carrier-protein] synthase activity
MT1254_RS07365	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MT1254_RS07370	COG0802	atpase or kinase
MT1254_RS07380	COG0456	acetyltransferase
MT1254_RS07385	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MT1254_RS07415	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
MT1254_RS07450	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MT1254_RS07455	COG0459	protein refolding
MT1254_RS07460	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MT1254_RS07465	COG1301	dicarboxylic acid transport
MT1254_RS07475	COG0516	GMP reductase activity
MT1254_RS07490	COG0519	Catalyzes the synthesis of GMP from XMP
MT1254_RS07490	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MT1254_RS07535	COG1051	belongs to the nudix hydrolase family
MT1254_RS07550	COG2326	polyphosphate kinase activity
MT1254_RS07555	COG0693	protein deglycase activity
MT1254_RS07560	COG1722	exodeoxyribonuclease VII activity
MT1254_RS07565	COG1570	exodeoxyribonuclease VII activity
MT1254_RS07575	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MT1254_RS07580	COG0471	metal ion transport
MT1254_RS07585	COG1322	Protein conserved in bacteria
MT1254_RS07600	COG2197	response regulator
MT1254_RS07605	COG4585	Histidine kinase
MT1254_RS07615	COG1131	(ABC) transporter
MT1254_RS07630	COG0012	GTP binding
MT1254_RS07710	COG1752	Esterase of the alpha-beta hydrolase superfamily
MT1254_RS07715	COG0488	(ABC) transporter
MT1254_RS07725	COG2130	NADP-dependent
MT1254_RS07730	COG2267	carboxylic ester hydrolase activity
MT1254_RS07740	COG1764	response to oxidative stress
MT1254_RS07760	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MT1254_RS07765	COG3268	Saccharopine dehydrogenase
MT1254_RS07780	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MT1254_RS07795	COG0477	Major facilitator Superfamily
MT1254_RS07800	COG1301	dicarboxylic acid transport
MT1254_RS07805	COG1174	glycine betaine transport
MT1254_RS07815	COG1174	glycine betaine transport
MT1254_RS07820	COG1732	Glycine betaine
MT1254_RS07830	COG1104	cysteine desulfurase activity
MT1254_RS07840	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MT1254_RS07850	COG0596	Alpha beta hydrolase
MT1254_RS07860	COG1528	Iron-storage protein
MT1254_RS07880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MT1254_RS07885	COG0428	transporter
MT1254_RS07895	COG4166	transmembrane transport
MT1254_RS07915	COG1217	gtp-binding protein TYPA
MT1254_RS07945	COG2171	N-acyltransferase activity
MT1254_RS07955	COG0765	amino acid transport
MT1254_RS07960	COG0765	amino acid transport
MT1254_RS07965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MT1254_RS07970	COG1126	abc transporter atp-binding protein
MT1254_RS07975	COG1611	Belongs to the LOG family
MT1254_RS08015	COG2239	Acts as a magnesium transporter
MT1254_RS08025	COG0469	pyruvate kinase activity
MT1254_RS08035	COG0613	PHP domain protein
MT1254_RS08040	COG0513	Belongs to the DEAD box helicase family
MT1254_RS08060	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MT1254_RS08065	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MT1254_RS08075	COG3253	May function as heme-dependent peroxidase
MT1254_RS08080	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MT1254_RS08085	COG0181	hydroxymethylbilane synthase activity
MT1254_RS08110	COG0113	porphobilinogen synthase activity
MT1254_RS08115	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MT1254_RS08175	COG1615	UPF0182 protein
MT1254_RS08285	COG1842	Phage shock protein A
MT1254_RS08295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MT1254_RS08300	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MT1254_RS08310	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MT1254_RS08315	COG0484	heat shock protein binding
MT1254_RS08325	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MT1254_RS08330	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MT1254_RS08335	COG0569	domain protein
MT1254_RS08345	COG0482	sulfurtransferase activity
MT1254_RS08360	COG0745	RESPONSE REGULATOR receiver
MT1254_RS08370	COG5401	PFAM Sporulation and spore germination
MT1254_RS08375	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MT1254_RS08380	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MT1254_RS08385	COG0653	protein targeting
MT1254_RS08440	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MT1254_RS08445	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MT1254_RS08450	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MT1254_RS08455	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MT1254_RS08465	COG2814	Major facilitator Superfamily
MT1254_RS08500	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MT1254_RS08530	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MT1254_RS08535	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MT1254_RS08540	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MT1254_RS08545	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MT1254_RS08550	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MT1254_RS08555	COG1438	arginine binding
MT1254_RS08565	COG0137	argininosuccinate synthase activity
MT1254_RS08570	COG0165	Argininosuccinate lyase
MT1254_RS08580	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MT1254_RS08605	COG0647	UMP catabolic process
MT1254_RS08615	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MT1254_RS08620	COG0497	DNA recombination
MT1254_RS08625	COG0494	nUDIX hydrolase
MT1254_RS08635	COG0504	CTP synthase activity
MT1254_RS08650	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MT1254_RS08655	COG2079	MmgE PrpD family protein
MT1254_RS08670	COG4565	transcriptional regulatory protein
MT1254_RS08675	COG3290	protein histidine kinase activity
MT1254_RS08680	COG1301	dicarboxylic acid transport
MT1254_RS08695	COG0287	Prephenate dehydrogenase
MT1254_RS08700	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MT1254_RS08705	COG1160	GTP binding
MT1254_RS08755	COG0542	response to heat
MT1254_RS08785	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MT1254_RS08790	COG3104	oligopeptide transport
MT1254_RS08795	COG0509	glycine decarboxylation via glycine cleavage system
MT1254_RS08820	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MT1254_RS08830	COG1022	Amp-dependent synthetase and ligase
MT1254_RS08845	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
MT1254_RS08850	COG0515	serine threonine protein kinase
MT1254_RS08850	COG2815	serine threonine protein kinase
MT1254_RS08855	COG1388	LysM domain
MT1254_RS08855	COG1705	Flagellar rod assembly protein muramidase FlgJ
MT1254_RS08865	COG0142	geranyltranstransferase activity
MT1254_RS08870	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MT1254_RS08880	COG2001	Belongs to the MraZ family
MT1254_RS08885	COG0275	rRNA processing
MT1254_RS08895	COG0768	penicillin binding
MT1254_RS08910	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MT1254_RS08915	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MT1254_RS08925	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MT1254_RS08930	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MT1254_RS08940	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MT1254_RS08945	COG1496	oxidoreductase activity
MT1254_RS08955	COG1799	cell septum assembly
MT1254_RS08970	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MT1254_RS08985	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MT1254_RS09005	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MT1254_RS09015	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MT1254_RS09020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MT1254_RS09025	COG0174	glutamine synthetase
MT1254_RS09040	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MT1254_RS09045	COG0321	lipoyl(octanoyl) transferase activity
MT1254_RS09060	COG0508	dehydrogenase complex catalyzes the overall conversion of
MT1254_RS09065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MT1254_RS09070	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MT1254_RS09085	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MT1254_RS09095	COG0187	DNA topoisomerase II activity
MT1254_RS09100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MT1254_RS09105	COG0318	PFAM AMP-dependent synthetase and ligase
MT1254_RS09110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MT1254_RS09150	COG0756	dUTP diphosphatase activity
MT1254_RS09175	COG0569	domain protein
MT1254_RS09180	COG0531	amino acid
MT1254_RS09185	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MT1254_RS09190	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MT1254_RS09195	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MT1254_RS09205	COG0667	Aldo Keto reductase
MT1254_RS09225	COG1024	Enoyl-CoA hydratase
MT1254_RS09225	COG1250	3-hydroxyacyl-CoA dehydrogenase
MT1254_RS09230	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
MT1254_RS09240	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MT1254_RS09255	COG0217	transcriptional regulatory protein
MT1254_RS09260	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MT1254_RS09265	COG0632	four-way junction helicase activity
MT1254_RS09270	COG2255	four-way junction helicase activity
MT1254_RS09285	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MT1254_RS09300	COG1196	nuclear chromosome segregation
MT1254_RS09315	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MT1254_RS09320	COG1490	D-aminoacyl-tRNA deacylase activity
MT1254_RS09335	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MT1254_RS09350	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MT1254_RS09365	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MT1254_RS09370	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MT1254_RS09375	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MT1254_RS09380	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MT1254_RS09385	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MT1254_RS09395	COG0540	Belongs to the ATCase OTCase family
MT1254_RS09400	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MT1254_RS09410	COG0505	Belongs to the CarA family
MT1254_RS09415	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MT1254_RS09420	COG0284	orotidine-5'-phosphate decarboxylase activity
MT1254_RS09430	COG0194	GDP metabolic process
MT1254_RS09435	COG1758	RNA polymerase activity
MT1254_RS09445	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MT1254_RS09460	COG3949	Membrane
MT1254_RS09465	COG0495	leucyl-tRNA aminoacylation
MT1254_RS09490	COG0268	Binds directly to 16S ribosomal RNA
MT1254_RS09500	COG0481	GTPase activity
MT1254_RS09520	COG1420	regulation of RNA biosynthetic process
MT1254_RS09525	COG0484	heat shock protein binding
MT1254_RS09540	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MT1254_RS09550	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MT1254_RS09555	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MT1254_RS09560	COG1381	Involved in DNA repair and RecF pathway recombination
MT1254_RS09565	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MT1254_RS09575	COG0167	dihydroorotate dehydrogenase activity
MT1254_RS09595	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MT1254_RS09600	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MT1254_RS09610	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MT1254_RS09615	COG0723	plastoquinol--plastocyanin reductase activity
MT1254_RS09625	COG1845	cytochrome c oxidase, subunit III
MT1254_RS09630	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MT1254_RS09660	COG0446	pyridine nucleotide-disulphide oxidoreductase
MT1254_RS09660	COG1902	pentaerythritol trinitrate reductase activity
MT1254_RS09680	COG1216	Glycosyl transferase, family 2
MT1254_RS09690	COG4581	dead DEAH box helicase
MT1254_RS09695	COG0805	protein transport
MT1254_RS09700	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MT1254_RS09720	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MT1254_RS09745	COG1222	aaa ATPase
MT1254_RS09760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MT1254_RS09770	COG0215	cysteine-tRNA ligase activity
MT1254_RS09775	COG1968	undecaprenyl-diphosphatase activity
MT1254_RS09790	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MT1254_RS09830	COG0297	glycogen (starch) synthase activity
MT1254_RS09835	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MT1254_RS09855	COG0254	rRNA binding
MT1254_RS09860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MT1254_RS09870	COG1119	ATPase activity
MT1254_RS09875	COG3830	Belongs to the UPF0237 family
MT1254_RS09875	COG0560	Phosphoserine phosphatase
MT1254_RS09880	COG1028	Short-chain dehydrogenase reductase Sdr
MT1254_RS09885	COG1028	Short-chain dehydrogenase reductase Sdr
MT1254_RS09905	COG0488	(ABC) transporter
MT1254_RS09915	COG2151	metal-sulfur cluster biosynthetic enzyme
MT1254_RS09920	COG0396	ATPase activity
MT1254_RS09940	COG1131	(ABC) transporter
MT1254_RS09955	COG0109	protoheme IX farnesyltransferase activity
MT1254_RS09965	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MT1254_RS09970	COG0166	Belongs to the GPI family
MT1254_RS09990	COG0149	triose-phosphate isomerase activity
MT1254_RS09995	COG0126	phosphoglycerate kinase activity
MT1254_RS10000	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MT1254_RS10005	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MT1254_RS10010	COG1481	regulation of sporulation
MT1254_RS10015	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MT1254_RS10020	COG1660	Displays ATPase and GTPase activities
MT1254_RS10025	COG0322	excinuclease ABC activity
MT1254_RS10045	COG4106	trans-aconitate 2-methyltransferase activity
MT1254_RS10080	COG0556	nucleotide-excision repair
MT1254_RS10085	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MT1254_RS10085	COG0237	dephospho-CoA kinase activity
MT1254_RS10095	COG1739	Uncharacterized protein family UPF0029
MT1254_RS10100	COG2813	Specifically methylates the guanine in position
MT1254_RS10105	COG0539	negative regulation of cytoplasmic translation
MT1254_RS10110	COG4552	Acetyltransferase involved in intracellular survival and related
MT1254_RS10120	COG2050	protein possibly involved in aromatic compounds catabolism
MT1254_RS10125	COG1320	monovalent cation:proton antiporter activity
MT1254_RS10135	COG1863	multisubunit Na H antiporter MnhE subunit
MT1254_RS10140	COG0651	ATP synthesis coupled electron transport
MT1254_RS10150	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MT1254_RS10150	COG2111	Na H antiporter
MT1254_RS10175	COG0067	glutamate synthase
MT1254_RS10175	COG0069	glutamate synthase activity
MT1254_RS10175	COG0070	glutamate synthase
MT1254_RS10180	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MT1254_RS10185	COG0159	tryptophan synthase activity
MT1254_RS10190	COG0133	tryptophan synthase activity
MT1254_RS10195	COG0134	indole-3-glycerol-phosphate synthase activity
MT1254_RS10215	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MT1254_RS10220	COG0107	imidazoleglycerol-phosphate synthase activity
MT1254_RS10225	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MT1254_RS10230	COG0140	phosphoribosyl-ATP diphosphatase activity
MT1254_RS10240	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MT1254_RS10245	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MT1254_RS10245	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MT1254_RS10265	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MT1254_RS10275	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MT1254_RS10280	COG0242	peptide deformylase activity
MT1254_RS10315	COG0076	glutamate decarboxylase activity
MT1254_RS10320	COG3486	L-lysine 6-monooxygenase (NADPH) activity
MT1254_RS10330	COG4264	IucA IucC family
MT1254_RS10360	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MT1254_RS10370	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MT1254_RS10405	COG2135	peptidase activity
MT1254_RS10420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MT1254_RS10440	COG1464	Belongs to the NlpA lipoprotein family
MT1254_RS10445	COG2011	ABC-type metal ion transport system permease component
MT1254_RS10450	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MT1254_RS10470	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MT1254_RS10475	COG1780	Probably involved in ribonucleotide reductase function
MT1254_RS10480	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MT1254_RS10520	COG0531	amino acid
MT1254_RS10525	COG1012	belongs to the aldehyde dehydrogenase family
MT1254_RS10540	COG1309	transcriptional regulator
MT1254_RS10555	COG0673	inositol 2-dehydrogenase activity
MT1254_RS10575	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MT1254_RS10585	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MT1254_RS10590	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MT1254_RS10595	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MT1254_RS10600	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MT1254_RS10605	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MT1254_RS10610	COG1530	ribonuclease E activity
MT1254_RS10620	COG0105	UTP biosynthetic process
MT1254_RS10630	COG0285	dihydrofolate synthase activity
MT1254_RS10635	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MT1254_RS10650	COG1648	precorrin-2 dehydrogenase activity
MT1254_RS10650	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MT1254_RS10675	COG0175	sulfate reduction
MT1254_RS10680	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MT1254_RS10695	COG0525	valine-tRNA ligase activity
MT1254_RS10705	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MT1254_RS10710	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MT1254_RS10715	COG0740	serine-type endopeptidase activity
MT1254_RS10720	COG0740	serine-type endopeptidase activity
MT1254_RS10725	COG0544	peptidyl-prolyl cis-trans isomerase activity
MT1254_RS10755	COG2072	flavoprotein involved in K transport
MT1254_RS10795	COG0629	single-stranded DNA binding
MT1254_RS10825	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MT1254_RS10835	COG4974	Belongs to the 'phage' integrase family
MT1254_RS11100	COG2823	Periplasmic or secreted lipoprotein
MT1254_RS11100	COG1652	LysM domain
MT1254_RS11145	COG2217	Heavy metal translocating P-type atpase
MT1254_RS11155	COG0242	peptide deformylase activity
MT1254_RS11160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MT1254_RS11180	COG3022	response to hydroperoxide
MT1254_RS11195	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MT1254_RS11200	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MT1254_RS11210	COG1045	serine acetyltransferase
MT1254_RS11215	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MT1254_RS11220	COG2326	polyphosphate kinase activity
MT1254_RS11260	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
MT1254_RS11275	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MT1254_RS11280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MT1254_RS11295	COG4974	Belongs to the 'phage' integrase family
MT1254_RS11310	COG0792	nuclease activity
MT1254_RS11320	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MT1254_RS11325	COG0681	Belongs to the peptidase S26 family
MT1254_RS11330	COG0681	Belongs to the peptidase S26 family
MT1254_RS11335	COG0335	large ribosomal subunit rRNA binding
MT1254_RS11340	COG0336	Belongs to the RNA methyltransferase TrmD family
MT1254_RS11345	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MT1254_RS11350	COG1837	Belongs to the UPF0109 family
MT1254_RS11355	COG0228	four-way junction DNA binding
MT1254_RS11375	COG2814	Major facilitator Superfamily
MT1254_RS11380	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MT1254_RS11390	COG1134	teichoic acid transport
MT1254_RS11400	COG0297	glycogen (starch) synthase activity
MT1254_RS11420	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MT1254_RS11430	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MT1254_RS11440	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MT1254_RS11460	COG1316	TRANSCRIPTIONal
MT1254_RS11465	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MT1254_RS11470	COG0571	ribonuclease III activity
MT1254_RS11475	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MT1254_RS11485	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MT1254_RS11490	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MT1254_RS11510	COG1461	Dihydroxyacetone kinase
MT1254_RS11515	COG1316	TRANSCRIPTIONal
MT1254_RS11525	COG1181	Belongs to the D-alanine--D-alanine ligase family
MT1254_RS11530	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MT1254_RS11540	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MT1254_RS11545	COG0066	3-isopropylmalate dehydratase activity
MT1254_RS11560	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MT1254_RS11600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MT1254_RS11605	COG0179	Fumarylacetoacetate (FAA) hydrolase
MT1254_RS11615	COG1966	Carbon starvation protein
MT1254_RS11620	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MT1254_RS11625	COG0473	3-isopropylmalate dehydrogenase activity
MT1254_RS11640	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MT1254_RS11645	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MT1254_RS11650	COG0440	acetolactate synthase activity
MT1254_RS11695	COG0579	oxidoreductase
MT1254_RS11700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MT1254_RS11705	COG0419	ATPase involved in DNA repair
MT1254_RS11710	COG0420	3'-5' exonuclease activity
MT1254_RS11725	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MT1254_RS11730	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MT1254_RS11735	COG1234	tRNA 3'-trailer cleavage
MT1254_RS11740	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MT1254_RS11750	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MT1254_RS11760	COG1335	isochorismatase
MT1254_RS11810	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
MT1254_RS11820	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MT1254_RS11825	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MT1254_RS11830	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MT1254_RS11835	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MT1254_RS11840	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MT1254_RS11845	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MT1254_RS11850	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MT1254_RS11855	COG0356	it plays a direct role in the translocation of protons across the membrane
MT1254_RS11870	COG0009	L-threonylcarbamoyladenylate synthase