locus-tag	class	description
BH695_RS00030	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BH695_RS00035	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BH695_RS00040	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BH695_RS00045	COG0202	RNA polymerase activity
BH695_RS00050	COG0203	ribosomal protein L17
BH695_RS00055	COG0101	tRNA pseudouridine synthase activity
BH695_RS00060	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BH695_RS00065	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BH695_RS00070	COG0254	rRNA binding
BH695_RS00090	COG1131	(ABC) transporter
BH695_RS00115	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BH695_RS00120	COG3259	Nickel-dependent hydrogenase
BH695_RS00155	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BH695_RS00160	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BH695_RS00175	COG0134	indole-3-glycerol-phosphate synthase activity
BH695_RS00205	COG0159	tryptophan synthase activity
BH695_RS00210	COG0463	Glycosyl transferase, family 2
BH695_RS00225	COG2048	Heterodisulfide reductase, subunit B
BH695_RS00250	COG0071	Belongs to the small heat shock protein (HSP20) family
BH695_RS00305	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BH695_RS00310	COG0745	RESPONSE REGULATOR receiver
BH695_RS00330	COG0302	gtp cyclohydrolase
BH695_RS00335	COG0113	porphobilinogen synthase activity
BH695_RS00345	COG1331	Highly conserved protein containing a thioredoxin domain
BH695_RS00350	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BH695_RS00375	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BH695_RS00405	COG0322	excinuclease ABC activity
BH695_RS00415	COG0473	3-isopropylmalate dehydrogenase activity
BH695_RS00425	COG1091	dTDP-4-dehydrorhamnose reductase activity
BH695_RS00435	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BH695_RS00445	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BH695_RS00450	COG0318	PFAM AMP-dependent synthetase and ligase
BH695_RS00460	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BH695_RS00470	COG0175	sulfate reduction
BH695_RS00475	COG0596	Alpha beta hydrolase
BH695_RS00500	COG3596	GTP binding
BH695_RS00515	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BH695_RS00520	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BH695_RS00525	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BH695_RS00530	COG0189	ligase activity
BH695_RS00535	COG3842	ATPase activity
BH695_RS00580	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BH695_RS00590	COG0670	Belongs to the BI1 family
BH695_RS00605	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BH695_RS00610	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BH695_RS00615	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BH695_RS00635	COG0488	(ABC) transporter
BH695_RS00640	COG0459	protein refolding
BH695_RS00660	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BH695_RS00695	COG0351	phosphomethylpyrimidine kinase
BH695_RS00700	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BH695_RS00740	COG1968	undecaprenyl-diphosphatase activity
BH695_RS00745	COG0678	peroxiredoxin activity
BH695_RS00745	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BH695_RS00765	COG0783	Belongs to the Dps family
BH695_RS00790	COG3118	belongs to the thioredoxin family
BH695_RS00795	COG0436	Aminotransferase
BH695_RS00845	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BH695_RS00860	COG0799	negative regulation of ribosome biogenesis
BH695_RS00865	COG1713	HD superfamily hydrolase involved in NAD metabolism
BH695_RS00870	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BH695_RS00875	COG0022	dehydrogenase e1 component
BH695_RS00875	COG0508	dehydrogenase complex catalyzes the overall conversion of
BH695_RS00880	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BH695_RS00885	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BH695_RS00890	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BH695_RS00895	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BH695_RS00905	COG1127	ABC transporter
BH695_RS00915	COG1459	type II secretion system
BH695_RS00925	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BH695_RS00930	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BH695_RS00935	COG1011	Hydrolase
BH695_RS00945	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BH695_RS00950	COG0594	ribonuclease P activity
BH695_RS00960	COG0706	membrane insertase activity
BH695_RS00995	COG0469	pyruvate kinase activity
BH695_RS01000	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BH695_RS01005	COG1192	Involved in chromosome partitioning
BH695_RS01015	COG0484	heat shock protein binding
BH695_RS01045	COG0651	ATP synthesis coupled electron transport
BH695_RS01050	COG1006	Multisubunit Na H antiporter MnhC subunit
BH695_RS01055	COG0651	ATP synthesis coupled electron transport
BH695_RS01075	COG0330	HflC and HflK could
BH695_RS01105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BH695_RS01110	COG2027	D-alanyl-D-alanine carboxypeptidase
BH695_RS01115	COG0297	glycogen (starch) synthase activity
BH695_RS01130	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BH695_RS01135	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BH695_RS01165	COG1088	dTDP-glucose 4,6-dehydratase activity
BH695_RS01175	COG0463	Glycosyl transferase, family 2
BH695_RS01195	COG0612	Peptidase, M16
BH695_RS01200	COG0612	Peptidase, M16
BH695_RS01250	COG0133	tryptophan synthase activity
BH695_RS01270	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BH695_RS01280	COG0515	serine threonine protein kinase
BH695_RS01280	COG3266	domain, Protein
BH695_RS01305	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BH695_RS01360	COG0793	Belongs to the peptidase S41A family
BH695_RS01450	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BH695_RS01455	COG0740	serine-type endopeptidase activity
BH695_RS01460	COG0544	peptidyl-prolyl cis-trans isomerase activity
BH695_RS01465	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BH695_RS01470	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BH695_RS01475	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BH695_RS01485	COG1691	(AIR) carboxylase
BH695_RS01490	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BH695_RS01520	COG0515	serine threonine protein kinase
BH695_RS01520	COG1357	PFAM Pentapeptide repeats (8 copies)
BH695_RS01615	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BH695_RS01615	COG3264	Mechanosensitive ion channel
BH695_RS01630	COG0442	prolyl-tRNA aminoacylation
BH695_RS01645	COG0525	valine-tRNA ligase activity
BH695_RS01670	COG0113	porphobilinogen synthase activity
BH695_RS01700	COG1366	Belongs to the anti-sigma-factor antagonist family
BH695_RS01705	COG0745	RESPONSE REGULATOR receiver
BH695_RS01745	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BH695_RS01750	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BH695_RS01775	COG0612	Peptidase, M16
BH695_RS01785	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BH695_RS01785	COG0574	Belongs to the PEP-utilizing enzyme family
BH695_RS01800	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BH695_RS01830	COG0793	Belongs to the peptidase S41A family
BH695_RS01835	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BH695_RS01845	COG1166	arginine decarboxylase activity
BH695_RS01860	COG0557	exoribonuclease II activity
BH695_RS01870	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BH695_RS01875	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BH695_RS01890	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BH695_RS01895	COG0174	glutamine synthetase
BH695_RS01920	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BH695_RS01935	COG0778	Nitroreductase
BH695_RS01940	COG2208	phosphoserine phosphatase activity
BH695_RS01945	COG2223	nitrite transmembrane transporter activity
BH695_RS01960	COG1316	TRANSCRIPTIONal
BH695_RS01975	COG0484	heat shock protein binding
BH695_RS01980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BH695_RS01985	COG3659	wide pore channel activity
BH695_RS02015	COG2161	toxin-antitoxin pair type II binding
BH695_RS02055	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BH695_RS02095	COG0017	Asparaginyl-tRNA synthetase
BH695_RS02110	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BH695_RS02120	COG0829	nickel cation binding
BH695_RS02125	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BH695_RS02130	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BH695_RS02135	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BH695_RS02145	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BH695_RS02150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BH695_RS02155	COG0058	SHG alpha-glucan phosphorylase activity
BH695_RS02230	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BH695_RS02240	COG4636	protein conserved in cyanobacteria
BH695_RS02245	COG0552	protein localization to endoplasmic reticulum
BH695_RS02250	COG1121	(ABC) transporter
BH695_RS02270	COG0802	atpase or kinase
BH695_RS02280	COG1472	Belongs to the glycosyl hydrolase 3 family
BH695_RS02285	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BH695_RS02355	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BH695_RS02365	COG4969	Belongs to the N-Me-Phe pilin family
BH695_RS02415	COG0450	alkyl hydroperoxide reductase
BH695_RS02540	COG0242	peptide deformylase activity
BH695_RS02545	COG3064	Membrane
BH695_RS02545	COG4991	sh3 domain protein
BH695_RS02545	COG0515	serine threonine protein kinase
BH695_RS02555	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BH695_RS02625	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BH695_RS02630	COG0515	serine threonine protein kinase
BH695_RS02630	COG3266	domain, Protein
BH695_RS02640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BH695_RS02710	COG0069	glutamate synthase activity
BH695_RS02710	COG0067	glutamate synthase
BH695_RS02710	COG0070	glutamate synthase
BH695_RS02765	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BH695_RS02770	COG0432	Pfam Uncharacterised protein family UPF0047
BH695_RS02830	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BH695_RS02885	COG2885	chlorophyll binding
BH695_RS02890	COG2885	chlorophyll binding
BH695_RS02960	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BH695_RS02970	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BH695_RS02985	COG0484	heat shock protein binding
BH695_RS02990	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BH695_RS03015	COG0463	Glycosyl transferase, family 2
BH695_RS03025	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BH695_RS03080	COG4251	negative regulation of phosphorylation
BH695_RS03085	COG3279	Response regulator of the LytR AlgR family
BH695_RS03110	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BH695_RS03115	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BH695_RS03125	COG0628	permease
BH695_RS03165	COG0601	transmembrane transport
BH695_RS03200	COG1309	transcriptional regulator
BH695_RS03215	COG0577	efflux transmembrane transporter activity
BH695_RS03215	COG1136	(ABC) transporter
BH695_RS03225	COG0731	radical SAM domain protein
BH695_RS03230	COG0768	penicillin binding
BH695_RS03235	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BH695_RS03295	COG2385	sporulation resulting in formation of a cellular spore
BH695_RS03300	COG0646	methionine synthase
BH695_RS03300	COG1410	methionine synthase
BH695_RS03305	COG0484	heat shock protein binding
BH695_RS03315	COG1181	Belongs to the D-alanine--D-alanine ligase family
BH695_RS03325	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BH695_RS03325	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BH695_RS03330	COG0237	dephospho-CoA kinase activity
BH695_RS03345	COG1473	amidohydrolase
BH695_RS03350	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BH695_RS03410	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BH695_RS03465	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BH695_RS03505	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BH695_RS03515	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BH695_RS03520	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BH695_RS03525	COG0573	inorganic phosphate transmembrane transporter activity
BH695_RS03530	COG0581	inorganic phosphate transmembrane transporter activity
BH695_RS03535	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BH695_RS03540	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BH695_RS03565	COG2091	lysine biosynthetic process via aminoadipic acid
BH695_RS03570	COG0438	transferase activity, transferring glycosyl groups
BH695_RS03575	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BH695_RS03645	COG0009	L-threonylcarbamoyladenylate synthase
BH695_RS03650	COG2205	protein histidine kinase activity
BH695_RS03650	COG0784	Response regulator, receiver
BH695_RS03655	COG0454	-acetyltransferase
BH695_RS03665	COG0429	hydrolase of the alpha beta-hydrolase fold
BH695_RS03680	COG0495	leucyl-tRNA aminoacylation
BH695_RS03685	COG0561	phosphatase activity
BH695_RS03690	COG0438	transferase activity, transferring glycosyl groups
BH695_RS03715	COG2244	polysaccharide biosynthetic process
BH695_RS03720	COG2244	polysaccharide biosynthetic process
BH695_RS03725	COG0463	Glycosyl transferase, family 2
BH695_RS03725	COG1216	Glycosyl transferase, family 2
BH695_RS03730	COG0438	transferase activity, transferring glycosyl groups
BH695_RS03735	COG1215	transferase activity, transferring glycosyl groups
BH695_RS03745	COG1215	transferase activity, transferring glycosyl groups
BH695_RS03755	COG0583	DNA-binding transcription factor activity
BH695_RS03760	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BH695_RS03770	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BH695_RS03815	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BH695_RS03830	COG1598	PFAM Uncharacterised protein family UPF0150
BH695_RS03850	COG0492	ferredoxin-NADP+ reductase activity
BH695_RS03865	COG0641	radical SAM
BH695_RS03875	COG1253	flavin adenine dinucleotide binding
BH695_RS03895	COG0557	exoribonuclease II activity
BH695_RS03910	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BH695_RS03915	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BH695_RS03975	COG4636	protein conserved in cyanobacteria
BH695_RS04000	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
BH695_RS04010	COG4178	(ABC) transporter
BH695_RS04030	COG0772	Belongs to the SEDS family
BH695_RS04035	COG0489	protein tyrosine kinase activity
BH695_RS04040	COG3217	Mosc domain protein beta barrel domain protein
BH695_RS04040	COG0633	Ferredoxin
BH695_RS04060	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BH695_RS04075	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BH695_RS04080	COG0424	maF-like protein
BH695_RS04115	COG0180	Tryptophanyl-tRNA synthetase
BH695_RS04145	COG0418	dihydroorotase activity
BH695_RS04150	COG1193	negative regulation of DNA recombination
BH695_RS04180	COG0702	epimerase
BH695_RS04190	COG1217	gtp-binding protein TYPA
BH695_RS04195	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BH695_RS04200	COG0681	Belongs to the peptidase S26 family
BH695_RS04225	COG0142	geranyltranstransferase activity
BH695_RS04240	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BH695_RS04295	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BH695_RS04315	COG4783	chaperone-mediated protein folding
BH695_RS04330	COG1834	amidinotransferase
BH695_RS04415	COG0542	response to heat
BH695_RS04420	COG0469	pyruvate kinase activity
BH695_RS04425	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BH695_RS04430	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BH695_RS04435	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BH695_RS04440	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BH695_RS04445	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BH695_RS04470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BH695_RS04475	COG1324	tolerance protein
BH695_RS04480	COG0237	dephospho-CoA kinase activity
BH695_RS04480	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BH695_RS04495	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BH695_RS04525	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BH695_RS04565	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BH695_RS04570	COG2027	D-alanyl-D-alanine carboxypeptidase
BH695_RS04575	COG0416	fatty acid biosynthetic process
BH695_RS04585	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BH695_RS04590	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BH695_RS04600	COG3239	Fatty acid desaturase
BH695_RS04605	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BH695_RS04620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BH695_RS04625	COG0440	acetolactate synthase activity
BH695_RS04630	COG0747	negative chemotaxis
BH695_RS04640	COG0586	Pfam SNARE associated Golgi protein
BH695_RS04650	COG0724	RNA recognition motif
BH695_RS04655	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BH695_RS04670	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BH695_RS04750	COG0653	protein targeting
BH695_RS04795	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BH695_RS04810	COG0018	arginyl-trna synthetase
BH695_RS04835	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BH695_RS04845	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BH695_RS04875	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
BH695_RS04880	COG4251	negative regulation of phosphorylation
BH695_RS04895	COG0784	Response regulator, receiver
BH695_RS04895	COG5002	protein histidine kinase activity
BH695_RS04930	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BH695_RS04940	COG4597	amino acid ABC transporter
BH695_RS04965	COG0295	cytidine deaminase activity
BH695_RS04970	COG2022	thiamine diphosphate biosynthetic process
BH695_RS04970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BH695_RS04980	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BH695_RS04985	COG0724	RNA recognition motif
BH695_RS04990	COG0517	IMP dehydrogenase activity
BH695_RS04990	COG0617	tRNA 3'-terminal CCA addition
BH695_RS04990	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BH695_RS05005	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BH695_RS05025	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BH695_RS05030	COG2226	methyltransferase
BH695_RS05045	COG3335	DDE superfamily endonuclease
BH695_RS05090	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BH695_RS05135	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BH695_RS05140	COG1799	cell septum assembly
BH695_RS05150	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BH695_RS05160	COG1007	ATP synthesis coupled electron transport
BH695_RS05180	COG0012	GTP binding
BH695_RS05185	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BH695_RS05225	COG0500	methyltransferase
BH695_RS05240	COG0475	glutathione-regulated potassium exporter activity
BH695_RS05245	COG0860	N-Acetylmuramoyl-L-alanine amidase
BH695_RS05250	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BH695_RS05305	COG0070	glutamate synthase
BH695_RS05305	COG0067	glutamate synthase
BH695_RS05305	COG0069	glutamate synthase activity
BH695_RS05310	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BH695_RS05315	COG0045	succinate-CoA ligase (ADP-forming) activity
BH695_RS05330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BH695_RS05335	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BH695_RS05380	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BH695_RS05385	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BH695_RS05410	COG4251	negative regulation of phosphorylation
BH695_RS05455	COG0546	phosphoglycolate phosphatase activity
BH695_RS05460	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BH695_RS05470	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BH695_RS05475	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BH695_RS05480	COG0312	modulator of DNA gyrase
BH695_RS05485	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BH695_RS05495	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BH695_RS05510	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BH695_RS05520	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BH695_RS05555	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BH695_RS05555	COG0426	domain, Protein
BH695_RS05565	COG0426	domain, Protein
BH695_RS05565	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BH695_RS05660	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BH695_RS05670	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BH695_RS05680	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BH695_RS05695	COG0270	DNA (cytosine-5-)-methyltransferase activity
BH695_RS05710	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BH695_RS05715	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BH695_RS05725	COG1132	(ABC) transporter
BH695_RS05735	COG0481	GTPase activity
BH695_RS05755	COG4106	trans-aconitate 2-methyltransferase activity
BH695_RS05790	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BH695_RS05795	COG2084	Dehydrogenase
BH695_RS05800	COG2154	pterin-4-alpha-carbinolamine dehydratase
BH695_RS05820	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BH695_RS05820	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BH695_RS05825	COG0004	ammonium transporteR
BH695_RS05830	COG0004	ammonium transporteR
BH695_RS05845	COG1028	Short-chain dehydrogenase reductase Sdr
BH695_RS05850	COG5002	protein histidine kinase activity
BH695_RS05855	COG0784	Response regulator, receiver
BH695_RS05860	COG4251	negative regulation of phosphorylation
BH695_RS05880	COG0339	signal peptide processing
BH695_RS05915	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BH695_RS05930	COG1070	Carbohydrate kinase
BH695_RS05940	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BH695_RS05980	COG0542	response to heat
BH695_RS06010	COG1215	transferase activity, transferring glycosyl groups
BH695_RS06020	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BH695_RS06045	COG0131	Imidazoleglycerol-phosphate dehydratase
BH695_RS06050	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BH695_RS06055	COG0121	glutamine amidotransferase
BH695_RS06060	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BH695_RS06070	COG1429	ligase activity, forming nitrogen-metal bonds
BH695_RS06100	COG0138	bifunctional purine biosynthesis protein purh
BH695_RS06135	COG0628	permease
BH695_RS06140	COG0411	ABC transporter
BH695_RS06205	COG0617	tRNA 3'-terminal CCA addition
BH695_RS06225	COG1002	Type II restriction enzyme, methylase subunits
BH695_RS06230	COG0415	Belongs to the DNA photolyase family
BH695_RS06235	COG0489	protein tyrosine kinase activity
BH695_RS06250	COG0275	rRNA processing
BH695_RS06330	COG2873	o-acetylhomoserine
BH695_RS06355	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BH695_RS06365	COG1285	pathogenesis
BH695_RS06370	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BH695_RS06375	COG2897	thiosulfate sulfurtransferase activity
BH695_RS06390	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BH695_RS06440	COG2217	Heavy metal translocating P-type atpase
BH695_RS06475	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BH695_RS06500	COG1040	competence protein
BH695_RS06515	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
BH695_RS06545	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BH695_RS06560	COG2319	Wd-40 repeat
BH695_RS06560	COG3903	Transcriptional regulator
BH695_RS06590	COG1674	ftsk spoiiie
BH695_RS06635	COG0538	isocitrate dehydrogenase activity
BH695_RS06665	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BH695_RS06670	COG2124	cytochrome p450
BH695_RS06675	COG0398	Pfam SNARE associated Golgi protein
BH695_RS06680	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BH695_RS06685	COG1530	ribonuclease E activity
BH695_RS06700	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BH695_RS06705	COG0493	'glutamate synthase
BH695_RS06725	COG1192	Involved in chromosome partitioning
BH695_RS06730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BH695_RS06735	COG3536	Protein conserved in bacteria
BH695_RS06740	COG0300	oxidoreductase activity
BH695_RS06755	COG1131	(ABC) transporter
BH695_RS06765	COG1413	lyase activity
BH695_RS06775	COG1413	lyase activity
BH695_RS06780	COG0469	pyruvate kinase activity
BH695_RS06785	COG3659	wide pore channel activity
BH695_RS06790	COG0515	serine threonine protein kinase
BH695_RS06810	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BH695_RS06820	COG0765	amino acid transport
BH695_RS06860	COG2226	methyltransferase
BH695_RS06885	COG0686	Belongs to the AlaDH PNT family
BH695_RS06905	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BH695_RS06945	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BH695_RS06950	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BH695_RS06965	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BH695_RS06970	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BH695_RS06975	COG2267	carboxylic ester hydrolase activity
BH695_RS06985	COG2197	response regulator
BH695_RS07010	COG0745	RESPONSE REGULATOR receiver
BH695_RS07015	COG0497	DNA recombination
BH695_RS07025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BH695_RS07035	COG0215	cysteine-tRNA ligase activity
BH695_RS07040	COG1174	glycine betaine transport
BH695_RS07050	COG0284	orotidine-5'-phosphate decarboxylase activity
BH695_RS07050	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BH695_RS07065	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BH695_RS07070	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BH695_RS07080	COG0505	Belongs to the CarA family
BH695_RS07090	COG2319	Wd-40 repeat
BH695_RS07090	COG1672	PFAM Archaeal ATPase
BH695_RS07110	COG0778	Nitroreductase
BH695_RS07125	COG0604	alcohol dehydrogenase
BH695_RS07125	COG3321	synthase
BH695_RS07135	COG3424	synthase
BH695_RS07155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BH695_RS07185	COG0515	serine threonine protein kinase
BH695_RS07190	COG1054	Belongs to the UPF0176 family
BH695_RS07200	COG1381	Involved in DNA repair and RecF pathway recombination
BH695_RS07235	COG0556	nucleotide-excision repair
BH695_RS07245	COG1615	UPF0182 protein
BH695_RS07250	COG1649	PFAM Uncharacterised BCR, COG1649
BH695_RS07255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BH695_RS07275	COG0667	Aldo Keto reductase
BH695_RS07290	COG0488	(ABC) transporter
BH695_RS07295	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BH695_RS07320	COG0513	Belongs to the DEAD box helicase family
BH695_RS07325	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BH695_RS07330	COG0434	BtpA family
BH695_RS07335	COG4243	Vitamin k epoxide reductase
BH695_RS07365	COG0672	)-iron permease
BH695_RS07380	COG0129	dihydroxy-acid dehydratase activity
BH695_RS07385	COG0713	ATP synthesis coupled electron transport
BH695_RS07390	COG2319	Wd-40 repeat
BH695_RS07390	COG3903	Transcriptional regulator
BH695_RS07410	COG0713	ATP synthesis coupled electron transport
BH695_RS07415	COG0839	Belongs to the complex I subunit 6 family
BH695_RS07420	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BH695_RS07425	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BH695_RS07430	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BH695_RS07440	COG4178	(ABC) transporter
BH695_RS07455	COG1028	Short-chain dehydrogenase reductase Sdr
BH695_RS07475	COG1028	Short-chain dehydrogenase reductase Sdr
BH695_RS07490	COG1304	FMN binding
BH695_RS07505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BH695_RS07505	COG3321	synthase
BH695_RS07505	COG1028	Short-chain dehydrogenase reductase Sdr
BH695_RS07505	COG0318	PFAM AMP-dependent synthetase and ligase
BH695_RS07505	COG0300	oxidoreductase activity
BH695_RS07515	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BH695_RS07570	COG0426	domain, Protein
BH695_RS07570	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BH695_RS07580	COG0837	glucose binding
BH695_RS07585	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BH695_RS07595	COG1252	NADH dehydrogenase
BH695_RS07605	COG1181	Belongs to the D-alanine--D-alanine ligase family
BH695_RS07620	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BH695_RS07635	COG0612	Peptidase, M16
BH695_RS07640	COG3001	Fructosamine kinase
BH695_RS07650	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BH695_RS07675	COG5002	protein histidine kinase activity
BH695_RS07680	COG0745	RESPONSE REGULATOR receiver
BH695_RS07700	COG2205	protein histidine kinase activity
BH695_RS07700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH695_RS07715	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BH695_RS07715	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BH695_RS07720	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BH695_RS07730	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BH695_RS07800	COG3773	Cell wall hydrolase
BH695_RS07800	COG3409	Peptidoglycan-binding domain 1 protein
BH695_RS07830	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BH695_RS07845	COG1598	PFAM Uncharacterised protein family UPF0150
BH695_RS07870	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BH695_RS07885	COG0484	heat shock protein binding
BH695_RS07900	COG0575	Belongs to the CDS family
BH695_RS07905	COG1587	Uroporphyrinogen-III synthase
BH695_RS07940	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BH695_RS07945	COG1160	GTP binding
BH695_RS07980	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BH695_RS07985	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
BH695_RS08005	COG1151	hydroxylamine reductase activity
BH695_RS08030	COG2385	sporulation resulting in formation of a cellular spore
BH695_RS08035	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BH695_RS08050	COG2912	Transglutaminase-like superfamily
BH695_RS08055	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BH695_RS08060	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BH695_RS08080	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BH695_RS08085	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BH695_RS08090	COG0590	tRNA wobble adenosine to inosine editing
BH695_RS08140	COG4636	protein conserved in cyanobacteria
BH695_RS08190	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BH695_RS08195	COG1473	amidohydrolase
BH695_RS08205	COG0284	orotidine-5'-phosphate decarboxylase activity
BH695_RS08215	COG2890	protein-(glutamine-N5) methyltransferase activity
BH695_RS08230	COG2319	Wd-40 repeat
BH695_RS08230	COG1672	PFAM Archaeal ATPase
BH695_RS08275	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BH695_RS08290	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BH695_RS08330	COG0596	Alpha beta hydrolase
BH695_RS08345	COG4221	oxidoreductase activity
BH695_RS08360	COG1136	(ABC) transporter
BH695_RS08360	COG0577	efflux transmembrane transporter activity
BH695_RS08400	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BH695_RS08405	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BH695_RS08415	COG1842	Phage shock protein A
BH695_RS08420	COG1842	Phage shock protein A
BH695_RS08440	COG0673	inositol 2-dehydrogenase activity
BH695_RS08450	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BH695_RS08460	COG5277	cytoskeleton organization
BH695_RS08495	COG1215	transferase activity, transferring glycosyl groups
BH695_RS08515	COG0725	ABC transporter, periplasmic molybdate-binding protein
BH695_RS08600	COG0110	maltose O-acetyltransferase activity
BH695_RS08610	COG0830	nickel cation binding
BH695_RS08620	COG0521	Mo-molybdopterin cofactor biosynthetic process
BH695_RS08660	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BH695_RS08665	COG0484	heat shock protein binding
BH695_RS08670	COG0483	inositol monophosphate 1-phosphatase activity
BH695_RS08675	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BH695_RS08690	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BH695_RS08705	COG0784	Response regulator, receiver
BH695_RS08705	COG0643	Histidine kinase
BH695_RS08705	COG0784	Response regulator, receiver
BH695_RS08705	COG2198	Histidine kinase
BH695_RS08705	COG2198	Histidine kinase
BH695_RS08705	COG0643	Histidine kinase
BH695_RS08710	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BH695_RS08725	COG0628	permease
BH695_RS08775	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BH695_RS08785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BH695_RS08800	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BH695_RS08815	COG1160	GTP binding
BH695_RS08860	COG0024	Methionine aminopeptidase
BH695_RS08865	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BH695_RS08870	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BH695_RS08875	COG0581	inorganic phosphate transmembrane transporter activity
BH695_RS08880	COG0573	inorganic phosphate transmembrane transporter activity
BH695_RS08885	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BH695_RS08900	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BH695_RS08905	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BH695_RS08910	COG1132	(ABC) transporter
BH695_RS08915	COG0857	belongs to the CobB CobQ family
BH695_RS08925	COG5002	protein histidine kinase activity
BH695_RS08935	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BH695_RS08940	COG0390	transport system, permease component
BH695_RS08970	COG0688	phosphatidylethanolamine metabolic process
BH695_RS09010	COG0316	Belongs to the HesB IscA family
BH695_RS09020	COG1950	PFAM Membrane protein of
BH695_RS09025	COG0564	pseudouridine synthase activity
BH695_RS09030	COG1748	Saccharopine dehydrogenase
BH695_RS09065	COG0025	NhaP-type Na H and K H
BH695_RS09085	COG0363	glucosamine-6-phosphate deaminase activity
BH695_RS09090	COG1716	ATPase activity
BH695_RS09095	COG0517	IMP dehydrogenase activity
BH695_RS09095	COG1994	Peptidase M50
BH695_RS09100	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BH695_RS09105	COG0149	triose-phosphate isomerase activity
BH695_RS09110	COG0179	Fumarylacetoacetate (FAA) hydrolase
BH695_RS09115	COG0360	Binds together with S18 to 16S ribosomal RNA
BH695_RS09130	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BH695_RS09205	COG0375	protein maturation
BH695_RS09250	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BH695_RS09255	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BH695_RS09290	COG0372	Belongs to the citrate synthase family
BH695_RS09315	COG2062	phosphohistidine phosphatase, SixA
BH695_RS09340	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BH695_RS09355	COG1187	pseudouridine synthase activity
BH695_RS09385	COG0515	serine threonine protein kinase
BH695_RS09385	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BH695_RS09395	COG1943	Transposase
BH695_RS09415	COG1363	Peptidase, m42
BH695_RS09420	COG0587	DNA-directed DNA polymerase activity
BH695_RS09495	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BH695_RS09500	COG1032	radical SAM domain protein
BH695_RS09505	COG1902	pentaerythritol trinitrate reductase activity
BH695_RS09520	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BH695_RS09540	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BH695_RS09545	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BH695_RS09575	COG0572	uridine kinase
BH695_RS09580	COG2197	response regulator
BH695_RS09600	COG2211	Major facilitator Superfamily
BH695_RS09610	COG0114	fumarate hydratase activity
BH695_RS09620	COG0193	aminoacyl-tRNA hydrolase activity
BH695_RS09630	COG0589	response to stress
BH695_RS09635	COG0024	Methionine aminopeptidase
BH695_RS09640	COG3118	belongs to the thioredoxin family
BH695_RS09650	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BH695_RS09665	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BH695_RS09695	COG1619	proteins homologs of microcin C7 resistance protein MccF
BH695_RS09700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BH695_RS09705	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BH695_RS09710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BH695_RS09720	COG0356	it plays a direct role in the translocation of protons across the membrane
BH695_RS09725	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BH695_RS09730	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BH695_RS09735	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BH695_RS09740	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BH695_RS09745	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BH695_RS09750	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BH695_RS09755	COG0811	peptide transport
BH695_RS09760	COG0848	biopolymer transport protein
BH695_RS09770	COG1252	NADH dehydrogenase
BH695_RS09780	COG1192	Involved in chromosome partitioning
BH695_RS09795	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BH695_RS09820	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BH695_RS09825	COG0049	tRNA binding
BH695_RS09830	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BH695_RS09835	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BH695_RS09840	COG0051	transcription antitermination factor activity, RNA binding
BH695_RS09845	COG0752	glycyl-tRNA synthetase alpha subunit
BH695_RS09855	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BH695_RS09860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BH695_RS09865	COG4372	Transposase
BH695_RS09870	COG4636	protein conserved in cyanobacteria
BH695_RS09875	COG4636	protein conserved in cyanobacteria
BH695_RS09890	COG0515	serine threonine protein kinase
BH695_RS09890	COG4991	sh3 domain protein
BH695_RS09890	COG3064	Membrane
BH695_RS09895	COG3608	succinylglutamate desuccinylase aspartoacylase
BH695_RS09900	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BH695_RS09905	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BH695_RS09920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BH695_RS09935	COG1012	belongs to the aldehyde dehydrogenase family
BH695_RS09950	COG0701	Predicted permease
BH695_RS09955	COG1606	tRNA processing
BH695_RS10045	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BH695_RS10055	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BH695_RS10055	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BH695_RS10060	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BH695_RS10070	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BH695_RS10075	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
BH695_RS10095	COG0305	Participates in initiation and elongation during chromosome replication
BH695_RS10095	COG1372	Participates in initiation and elongation during chromosome replication
BH695_RS10115	COG0023	Translation Initiation Factor
BH695_RS10120	COG3046	protein related to deoxyribodipyrimidine photolyase
BH695_RS10155	COG0371	Dehydrogenase
BH695_RS10165	COG0602	queuosine metabolic process
BH695_RS10180	COG0523	cobalamin synthesis protein
BH695_RS10190	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BH695_RS10200	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BH695_RS10205	COG0237	dephospho-CoA kinase activity
BH695_RS10215	COG0741	lytic transglycosylase activity
BH695_RS10225	COG0529	Catalyzes the synthesis of activated sulfate
BH695_RS10230	COG1132	(ABC) transporter
BH695_RS10240	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BH695_RS10245	COG2217	Heavy metal translocating P-type atpase
BH695_RS10330	COG0577	efflux transmembrane transporter activity
BH695_RS10330	COG1136	(ABC) transporter
BH695_RS10340	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BH695_RS10380	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BH695_RS10385	COG0842	Transport permease protein
BH695_RS10385	COG1131	(ABC) transporter
BH695_RS10385	COG1716	ATPase activity
BH695_RS10390	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BH695_RS10405	COG2046	Belongs to the sulfate adenylyltransferase family
BH695_RS10445	COG0537	adenosine 5'-monophosphoramidase activity
BH695_RS10450	COG0606	chelatase, subunit chli
BH695_RS10480	COG1187	pseudouridine synthase activity
BH695_RS10490	COG1253	flavin adenine dinucleotide binding
BH695_RS10515	COG0596	Alpha beta hydrolase
BH695_RS10525	COG0616	signal peptide processing
BH695_RS10540	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BH695_RS10555	COG0006	proline dipeptidase activity
BH695_RS10565	COG0384	phenazine biosynthesis protein PhzF
BH695_RS10575	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BH695_RS10585	COG0352	thiamine-phosphate diphosphorylase activity
BH695_RS10600	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BH695_RS10600	COG0140	phosphoribosyl-ATP diphosphatase activity
BH695_RS10605	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BH695_RS10610	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BH695_RS10635	COG1131	(ABC) transporter
BH695_RS10640	COG1376	ErfK ybiS ycfS ynhG family protein
BH695_RS10645	COG4095	Psort location CytoplasmicMembrane, score
BH695_RS10685	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BH695_RS10690	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BH695_RS10755	COG1122	ATPase activity
BH695_RS10765	COG3239	Fatty acid desaturase
BH695_RS10770	COG0515	serine threonine protein kinase
BH695_RS10770	COG1357	PFAM Pentapeptide repeats (8 copies)
BH695_RS10775	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BH695_RS10805	COG0494	nUDIX hydrolase
BH695_RS10810	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BH695_RS10815	COG1185	polyribonucleotide nucleotidyltransferase activity
BH695_RS10825	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BH695_RS10830	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BH695_RS10835	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BH695_RS10840	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BH695_RS10845	COG1702	phosphate starvation-inducible protein PhoH
BH695_RS10870	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BH695_RS10870	COG0515	serine threonine protein kinase
BH695_RS10910	COG1702	phosphate starvation-inducible protein PhoH
BH695_RS10920	COG0357	Ribosomal RNA small subunit methyltransferase G
BH695_RS10925	COG0387	Pfam Sodium calcium exchanger
BH695_RS10950	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BH695_RS10955	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BH695_RS10965	COG0598	Magnesium transport protein CorA
BH695_RS10975	COG2205	protein histidine kinase activity
BH695_RS11040	COG4974	Belongs to the 'phage' integrase family
BH695_RS11075	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BH695_RS11090	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BH695_RS11090	COG0758	DNA mediated transformation
BH695_RS11095	COG3118	belongs to the thioredoxin family
BH695_RS11100	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BH695_RS11135	COG0587	DNA-directed DNA polymerase activity
BH695_RS11145	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
BH695_RS11150	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BH695_RS11160	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BH695_RS11175	COG1077	Cell shape determining protein MreB Mrl
BH695_RS11180	COG0629	single-stranded DNA binding
BH695_RS11195	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BH695_RS11200	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BH695_RS11200	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BH695_RS11205	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BH695_RS11210	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BH695_RS11260	COG0850	regulation of cytokinetic process
BH695_RS11265	COG2894	cell division
BH695_RS11270	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BH695_RS11280	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BH695_RS11285	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BH695_RS11290	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BH695_RS11380	COG1546	Belongs to the CinA family
BH695_RS11380	COG1058	Belongs to the CinA family
BH695_RS11385	COG0443	Heat shock 70 kDa protein
BH695_RS11410	COG0439	Biotin carboxylase
BH695_RS11415	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BH695_RS11450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BH695_RS11470	COG4968	Prepilin-type N-terminal cleavage methylation domain
BH695_RS11475	COG4968	Prepilin-type N-terminal cleavage methylation domain
BH695_RS11500	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BH695_RS11525	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
BH695_RS11525	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
BH695_RS11530	COG0583	DNA-binding transcription factor activity
BH695_RS11535	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BH695_RS11570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BH695_RS11585	COG0861	Integral membrane protein TerC family
BH695_RS11605	COG0574	Belongs to the PEP-utilizing enzyme family
BH695_RS11605	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BH695_RS11625	COG0574	Belongs to the PEP-utilizing enzyme family
BH695_RS11625	COG3848	Pyruvate phosphate dikinase
BH695_RS11670	COG0321	lipoyl(octanoyl) transferase activity
BH695_RS11675	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BH695_RS11680	COG0071	Belongs to the small heat shock protein (HSP20) family
BH695_RS11690	COG0009	L-threonylcarbamoyladenylate synthase
BH695_RS11695	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
BH695_RS11710	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BH695_RS11730	COG0577	efflux transmembrane transporter activity
BH695_RS11730	COG1136	(ABC) transporter
BH695_RS11735	COG0166	Belongs to the GPI family
BH695_RS11740	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BH695_RS11775	COG1598	PFAM Uncharacterised protein family UPF0150
BH695_RS11805	COG0436	Aminotransferase
BH695_RS11820	COG1002	Type II restriction enzyme, methylase subunits
BH695_RS11845	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BH695_RS11855	COG0742	ribosomal rna small subunit methyltransferase
BH695_RS11870	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BH695_RS11885	COG2815	serine threonine protein kinase
BH695_RS11885	COG0515	serine threonine protein kinase
BH695_RS11900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BH695_RS11910	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BH695_RS11915	COG0275	rRNA processing
BH695_RS11925	COG0436	Aminotransferase
BH695_RS11940	COG0312	modulator of DNA gyrase
BH695_RS11950	COG0312	modulator of DNA gyrase
BH695_RS11990	COG1045	serine acetyltransferase
BH695_RS11995	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BH695_RS12045	COG0714	Associated with various cellular activities
BH695_RS12060	COG0196	riboflavin kinase activity
BH695_RS12065	COG0081	regulation of translation
BH695_RS12070	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BH695_RS12075	COG0250	Participates in transcription elongation, termination and antitermination
BH695_RS12080	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BH695_RS12090	COG0335	large ribosomal subunit rRNA binding
BH695_RS12105	COG2319	Wd-40 repeat
BH695_RS12105	COG4249	Peptidase C14 caspase catalytic subunit p20
BH695_RS12140	COG0205	6-phosphofructokinase activity
BH695_RS12155	COG0674	pyruvate-flavodoxin oxidoreductase activity
BH695_RS12155	COG1013	pyruvate-flavodoxin oxidoreductase activity
BH695_RS12155	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BH695_RS12155	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BH695_RS12165	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BH695_RS12195	COG2886	Uncharacterised protein family (UPF0175)
BH695_RS12200	COG0629	single-stranded DNA binding
BH695_RS12205	COG0765	amino acid transport
BH695_RS12215	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BH695_RS12220	COG0628	permease
BH695_RS12225	COG0697	spore germination
BH695_RS12235	COG1234	tRNA 3'-trailer cleavage
BH695_RS12240	COG2226	methyltransferase
BH695_RS12245	COG4399	Belongs to the UPF0754 family
BH695_RS12280	COG2066	Belongs to the glutaminase family
BH695_RS12285	COG0288	reversible hydration of carbon dioxide
BH695_RS12315	COG0450	alkyl hydroperoxide reductase
BH695_RS12320	COG1555	photosystem II stabilization
BH695_RS12325	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BH695_RS12340	COG0827	DNA restriction-modification system
BH695_RS12345	COG0827	DNA restriction-modification system
BH695_RS12405	COG1196	nuclear chromosome segregation
BH695_RS12420	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BH695_RS12425	COG0251	oxidation-reduction process
BH695_RS12430	COG1192	Involved in chromosome partitioning
BH695_RS12440	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BH695_RS12445	COG4636	protein conserved in cyanobacteria
BH695_RS12470	COG1480	7TM receptor with intracellular HD hydrolase
BH695_RS12500	COG0649	NAD binding
BH695_RS12505	COG1012	belongs to the aldehyde dehydrogenase family
BH695_RS12510	COG0033	Phosphoglucomutase
BH695_RS12520	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BH695_RS12520	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BH695_RS12525	COG0400	carboxylic ester hydrolase activity
BH695_RS12530	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BH695_RS12530	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BH695_RS12570	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BH695_RS12570	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BH695_RS12630	COG1598	PFAM Uncharacterised protein family UPF0150
BH695_RS12645	COG4948	Mandelate Racemase Muconate Lactonizing
BH695_RS12655	COG0745	RESPONSE REGULATOR receiver
BH695_RS12665	COG5398	heme oxygenase
BH695_RS12675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BH695_RS12680	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BH695_RS12685	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BH695_RS12730	COG0501	Belongs to the peptidase M48B family
BH695_RS12750	COG1028	Short-chain dehydrogenase reductase Sdr
BH695_RS12825	COG1404	Belongs to the peptidase S8 family
BH695_RS12850	COG1944	ATP diphosphatase activity
BH695_RS12920	COG0714	Associated with various cellular activities
BH695_RS12945	COG3961	Belongs to the TPP enzyme family
BH695_RS12950	COG1960	acyl-CoA dehydrogenase activity
BH695_RS12980	COG0419	ATPase involved in DNA repair
BH695_RS13000	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BH695_RS13015	COG0463	Glycosyl transferase, family 2
BH695_RS13040	COG1104	cysteine desulfurase activity
BH695_RS13045	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BH695_RS13050	COG0318	PFAM AMP-dependent synthetase and ligase
BH695_RS13055	COG4948	Mandelate Racemase Muconate Lactonizing
BH695_RS13070	COG2886	Uncharacterised protein family (UPF0175)
BH695_RS13095	COG0243	molybdopterin cofactor binding
BH695_RS13100	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BH695_RS13105	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BH695_RS13115	COG0668	transmembrane transport
BH695_RS13120	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BH695_RS13135	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BH695_RS13145	COG2154	pterin-4-alpha-carbinolamine dehydratase
BH695_RS13155	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BH695_RS13175	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BH695_RS13185	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BH695_RS13245	COG4974	Belongs to the 'phage' integrase family
BH695_RS13285	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BH695_RS13330	COG0228	four-way junction DNA binding
BH695_RS13340	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BH695_RS13355	COG0616	signal peptide processing
BH695_RS13365	COG0589	response to stress
BH695_RS13380	COG0604	alcohol dehydrogenase
BH695_RS13385	COG3000	fatty acid hydroxylase
BH695_RS13385	COG0300	oxidoreductase activity
BH695_RS13390	COG1215	transferase activity, transferring glycosyl groups
BH695_RS13445	COG3794	PFAM blue (type 1) copper domain protein
BH695_RS13460	COG0720	synthase
BH695_RS13465	COG0587	DNA-directed DNA polymerase activity
BH695_RS13470	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BH695_RS13495	COG0515	serine threonine protein kinase
BH695_RS13540	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BH695_RS13545	COG0028	Belongs to the TPP enzyme family
BH695_RS13550	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BH695_RS13555	COG2264	protein methyltransferase activity
BH695_RS13560	COG0314	molybdopterin synthase activity
BH695_RS13565	COG0779	Required for maturation of 30S ribosomal subunits
BH695_RS13570	COG1032	radical SAM domain protein
BH695_RS13585	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BH695_RS13600	COG1215	transferase activity, transferring glycosyl groups
BH695_RS13615	COG0083	homoserine kinase activity
BH695_RS13675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BH695_RS13685	COG0504	CTP synthase activity
BH695_RS13690	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BH695_RS13720	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BH695_RS13775	COG0515	serine threonine protein kinase
BH695_RS13780	COG1982	Orn Lys Arg decarboxylase major
BH695_RS13795	COG0528	UMP kinase activity
BH695_RS13800	COG0233	cytoplasmic translational termination
BH695_RS13805	COG0515	serine threonine protein kinase
BH695_RS13815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BH695_RS13930	COG2337	Toxic component of a toxin-antitoxin (TA) module
BH695_RS13945	COG1803	Methylglyoxal synthase
BH695_RS13945	COG1597	lipid kinase activity
BH695_RS13950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH695_RS13955	COG1836	PFAM Integral membrane protein DUF92
BH695_RS13965	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BH695_RS13975	COG1492	cobalamin metabolic process
BH695_RS13995	COG2197	response regulator
BH695_RS14005	COG0740	serine-type endopeptidase activity
BH695_RS14010	COG0740	serine-type endopeptidase activity
BH695_RS14015	COG4221	oxidoreductase activity
BH695_RS14015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BH695_RS14015	COG0604	alcohol dehydrogenase
BH695_RS14015	COG3321	synthase
BH695_RS14020	COG0511	ligase activity, forming carbon-carbon bonds
BH695_RS14025	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BH695_RS14090	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BH695_RS14100	COG0563	adenylate kinase activity
BH695_RS14105	COG0201	protein transport
BH695_RS14115	COG0200	Binds to the 23S rRNA
BH695_RS14120	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BH695_RS14125	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BH695_RS14130	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BH695_RS14135	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BH695_RS14140	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BH695_RS14145	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BH695_RS14150	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BH695_RS14155	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BH695_RS14160	COG0255	Belongs to the universal ribosomal protein uL29 family
BH695_RS14165	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BH695_RS14170	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BH695_RS14175	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BH695_RS14180	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BH695_RS14185	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BH695_RS14190	COG0089	rRNA binding
BH695_RS14195	COG0088	Forms part of the polypeptide exit tunnel
BH695_RS14200	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BH695_RS14225	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BH695_RS14235	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BH695_RS14240	COG0735	belongs to the Fur family
BH695_RS14245	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BH695_RS14250	COG0047	phosphoribosylformylglycinamidine synthase activity
BH695_RS14360	COG0170	dolichyl monophosphate biosynthetic process
BH695_RS14365	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BH695_RS14375	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BH695_RS14430	COG2337	Toxic component of a toxin-antitoxin (TA) module
BH695_RS14455	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BH695_RS14465	COG0217	transcriptional regulatory protein
BH695_RS14470	COG0602	queuosine metabolic process
BH695_RS14475	COG1690	Belongs to the RtcB family
BH695_RS14480	COG0443	Heat shock 70 kDa protein
BH695_RS14485	COG0786	glutamate:sodium symporter activity
BH695_RS14515	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BH695_RS14535	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BH695_RS14560	COG1619	proteins homologs of microcin C7 resistance protein MccF
BH695_RS14570	COG0517	IMP dehydrogenase activity
BH695_RS14570	COG0516	GMP reductase activity
BH695_RS14575	COG4636	protein conserved in cyanobacteria
BH695_RS14580	COG0157	Belongs to the NadC ModD family
BH695_RS14605	COG2385	sporulation resulting in formation of a cellular spore
BH695_RS14605	COG2247	cell wall binding repeat
BH695_RS14610	COG0569	domain protein
BH695_RS14615	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BH695_RS14620	COG0438	transferase activity, transferring glycosyl groups
BH695_RS14630	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BH695_RS14660	COG1192	Involved in chromosome partitioning
BH695_RS14670	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BH695_RS14680	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BH695_RS14710	COG0010	Belongs to the arginase family
BH695_RS14715	COG0375	protein maturation
BH695_RS14720	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BH695_RS14795	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BH695_RS14810	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BH695_RS14815	COG1049	propionate catabolic process, 2-methylcitrate cycle
BH695_RS14845	COG2326	polyphosphate kinase activity
BH695_RS14870	COG3631	Ketosteroid isomerase-related protein
BH695_RS14875	COG1116	anion transmembrane transporter activity
BH695_RS14955	COG1252	NADH dehydrogenase
BH695_RS14980	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BH695_RS15020	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BH695_RS15025	COG1494	fructose-1,6-bisphosphatase
BH695_RS15030	COG0730	response to heat
BH695_RS15095	COG0259	pyridoxamine-phosphate oxidase activity
BH695_RS15110	COG0514	ATP-dependent DNA helicase (RecQ)
BH695_RS15120	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BH695_RS15135	COG0438	transferase activity, transferring glycosyl groups
BH695_RS15165	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BH695_RS15175	COG0592	DNA-directed DNA polymerase activity
BH695_RS15180	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BH695_RS15185	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BH695_RS15190	COG4178	(ABC) transporter
BH695_RS15210	COG3321	synthase
BH695_RS15210	COG0604	alcohol dehydrogenase
BH695_RS15250	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BH695_RS15295	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BH695_RS15375	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BH695_RS15375	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BH695_RS15410	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BH695_RS15420	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BH695_RS15430	COG3258	Cytochrome c
BH695_RS15435	COG0723	plastoquinol--plastocyanin reductase activity
BH695_RS15445	COG2361	Protein of unknown function DUF86
BH695_RS15450	COG2852	Protein conserved in bacteria
BH695_RS15470	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BH695_RS15470	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BH695_RS15485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BH695_RS15490	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BH695_RS15535	COG1181	Belongs to the D-alanine--D-alanine ligase family
BH695_RS15535	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BH695_RS15540	COG4242	Belongs to the peptidase S51 family
BH695_RS15545	COG0336	Belongs to the RNA methyltransferase TrmD family
BH695_RS15630	COG0316	Belongs to the HesB IscA family
BH695_RS15635	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BH695_RS15655	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BH695_RS15660	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BH695_RS15675	COG0542	response to heat
BH695_RS15705	COG1234	tRNA 3'-trailer cleavage
BH695_RS15715	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BH695_RS15725	COG1640	4-alpha-glucanotransferase
BH695_RS15770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BH695_RS15800	COG5000	phosphorelay sensor kinase activity
BH695_RS15800	COG5002	protein histidine kinase activity
BH695_RS15815	COG3119	arylsulfatase activity
BH695_RS15820	COG2095	MarC family integral membrane protein
BH695_RS15835	COG0076	glutamate decarboxylase activity
BH695_RS15850	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BH695_RS15855	COG4208	sulfate ABC transporter
BH695_RS15860	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BH695_RS15870	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BH695_RS15880	COG0571	ribonuclease III activity
BH695_RS15965	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BH695_RS15970	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BH695_RS16005	COG2052	Domain of unknown function (DUF370)
BH695_RS16010	COG0194	GDP metabolic process
BH695_RS16015	COG0740	serine-type endopeptidase activity
BH695_RS16025	COG1104	cysteine desulfurase activity
BH695_RS16030	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BH695_RS16055	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
BH695_RS16065	COG2066	Belongs to the glutaminase family
BH695_RS16070	COG0303	'Molybdopterin
BH695_RS16090	COG0745	RESPONSE REGULATOR receiver
BH695_RS16095	COG0187	DNA topoisomerase II activity
BH695_RS16095	COG1372	Participates in initiation and elongation during chromosome replication
BH695_RS16105	COG2131	deaminase
BH695_RS16110	COG0310	cobalt ion transport
BH695_RS16120	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BH695_RS16125	COG1122	ATPase activity
BH695_RS16145	COG0737	Belongs to the 5'-nucleotidase family
BH695_RS16190	COG0463	Glycosyl transferase, family 2
BH695_RS16220	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BH695_RS16225	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BH695_RS16225	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BH695_RS16235	COG0859	PFAM glycosyl transferase family 9
BH695_RS16245	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BH695_RS16280	COG0539	negative regulation of cytoplasmic translation
BH695_RS16285	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BH695_RS16295	COG0222	ribosome binding
BH695_RS16300	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BH695_RS16305	COG0804	urea catabolic process
BH695_RS16350	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
BH695_RS16385	COG0315	cyclic pyranopterin monophosphate synthase activity
BH695_RS16390	COG1429	ligase activity, forming nitrogen-metal bonds
BH695_RS16395	COG0426	domain, Protein
BH695_RS16395	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BH695_RS16410	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BH695_RS16410	COG0426	domain, Protein
BH695_RS16420	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BH695_RS16440	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BH695_RS16485	COG2197	response regulator
BH695_RS16490	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BH695_RS16505	COG2274	protein secretion by the type I secretion system
BH695_RS16525	COG0454	-acetyltransferase
BH695_RS16535	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BH695_RS16540	COG0085	RNA polymerase activity
BH695_RS16545	COG0084	hydrolase, TatD family'
BH695_RS16550	COG0268	Binds directly to 16S ribosomal RNA
BH695_RS16560	COG0463	Glycosyl transferase, family 2
BH695_RS16635	COG1773	rubredoxin
BH695_RS16640	COG4447	cellulose binding
BH695_RS16700	COG3937	granule-associated protein
BH695_RS16705	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BH695_RS16710	COG0631	protein serine/threonine phosphatase activity
BH695_RS16720	COG0837	glucose binding
BH695_RS16730	COG2319	Wd-40 repeat
BH695_RS16730	COG1672	PFAM Archaeal ATPase
BH695_RS16745	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BH695_RS16755	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BH695_RS16810	COG2226	methyltransferase
BH695_RS16820	COG0805	protein transport
BH695_RS16835	COG0805	protein transport
BH695_RS16850	COG0716	FMN binding
BH695_RS16855	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BH695_RS16905	COG2319	Wd-40 repeat
BH695_RS16905	COG3903	Transcriptional regulator
BH695_RS16910	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BH695_RS16915	COG0523	cobalamin synthesis protein
BH695_RS16960	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BH695_RS16970	COG2226	methyltransferase
BH695_RS16980	COG2217	Heavy metal translocating P-type atpase
BH695_RS17010	COG4172	Belongs to the ABC transporter superfamily
BH695_RS17015	COG0154	amidase activity
BH695_RS17020	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BH695_RS17040	COG0667	Aldo Keto reductase
BH695_RS17055	COG1525	nuclease
BH695_RS17070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BH695_RS17110	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BH695_RS17115	COG0402	S-adenosylhomocysteine deaminase activity
BH695_RS17125	COG0039	L-malate dehydrogenase activity
BH695_RS17135	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BH695_RS17150	COG0768	penicillin binding
BH695_RS17160	COG2133	pyrroloquinoline quinone binding
BH695_RS17165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BH695_RS17195	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BH695_RS17200	COG1971	Probably functions as a manganese efflux pump
BH695_RS17260	COG3335	DDE superfamily endonuclease
BH695_RS17320	COG1376	ErfK ybiS ycfS ynhG family protein
BH695_RS17330	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BH695_RS17335	COG3549	Plasmid maintenance system killer
BH695_RS17355	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BH695_RS17360	COG0601	transmembrane transport
BH695_RS17430	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BH695_RS17435	COG1489	DNA binding
BH695_RS17440	COG3688	RNA-binding protein containing a PIN domain
BH695_RS17445	COG1122	ATPase activity
BH695_RS17455	COG2161	toxin-antitoxin pair type II binding
BH695_RS17520	COG0135	phosphoribosylanthranilate isomerase activity
BH695_RS17525	COG0302	gtp cyclohydrolase
BH695_RS17530	COG0300	oxidoreductase activity
BH695_RS17550	COG5002	protein histidine kinase activity
BH695_RS17590	COG0025	NhaP-type Na H and K H
BH695_RS17595	COG1126	abc transporter atp-binding protein
BH695_RS17640	COG1518	maintenance of DNA repeat elements
BH695_RS17640	COG1468	defense response to virus
BH695_RS17730	COG1752	Esterase of the alpha-beta hydrolase superfamily
BH695_RS17730	COG1752	Esterase of the alpha-beta hydrolase superfamily
BH695_RS17750	COG0519	Catalyzes the synthesis of GMP from XMP
BH695_RS17750	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BH695_RS17755	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
BH695_RS17770	COG2197	response regulator
BH695_RS17805	COG0165	Argininosuccinate lyase
BH695_RS17815	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BH695_RS17825	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BH695_RS17830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BH695_RS17835	COG1116	anion transmembrane transporter activity
BH695_RS17835	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BH695_RS17840	COG1116	anion transmembrane transporter activity
BH695_RS17860	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BH695_RS17870	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BH695_RS17915	COG0724	RNA recognition motif
BH695_RS17920	COG0724	RNA recognition motif
BH695_RS17925	COG0058	SHG alpha-glucan phosphorylase activity
BH695_RS17995	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
BH695_RS18000	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BH695_RS18005	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
BH695_RS18065	COG0183	Belongs to the thiolase family
BH695_RS18070	COG1028	Short-chain dehydrogenase reductase Sdr
BH695_RS18090	COG3243	poly(R)-hydroxyalkanoic acid synthase
BH695_RS18095	COG0644	oxidoreductase
BH695_RS18100	COG1446	asparaginase
BH695_RS18105	COG0772	Belongs to the SEDS family
BH695_RS18115	COG0793	Belongs to the peptidase S41A family
BH695_RS18130	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BH695_RS18150	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BH695_RS18165	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BH695_RS18170	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BH695_RS18215	COG1104	cysteine desulfurase activity
BH695_RS18250	COG0517	IMP dehydrogenase activity
BH695_RS18265	COG3118	belongs to the thioredoxin family
BH695_RS18280	COG0583	DNA-binding transcription factor activity
BH695_RS18285	COG0659	secondary active sulfate transmembrane transporter activity
BH695_RS18290	COG0475	glutathione-regulated potassium exporter activity
BH695_RS18305	COG0739	heme binding
BH695_RS18310	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BH695_RS18310	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BH695_RS18320	COG0406	alpha-ribazole phosphatase activity
BH695_RS18325	COG0105	UTP biosynthetic process
BH695_RS18335	COG0564	pseudouridine synthase activity
BH695_RS18340	COG0443	Heat shock 70 kDa protein
BH695_RS18345	COG0484	heat shock protein binding
BH695_RS18350	COG0167	dihydroorotate dehydrogenase activity
BH695_RS18360	COG0285	dihydrofolate synthase activity
BH695_RS18365	COG2045	Belongs to the ComB family
BH695_RS18400	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BH695_RS18410	COG0385	Bile acid
BH695_RS18420	COG1132	(ABC) transporter
BH695_RS18430	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BH695_RS18435	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BH695_RS18440	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BH695_RS18445	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BH695_RS18450	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BH695_RS18455	COG0832	Belongs to the urease beta subunit family
BH695_RS18460	COG0831	urea catabolic process
BH695_RS18495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BH695_RS18505	COG0540	Belongs to the ATCase OTCase family
BH695_RS18525	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BH695_RS18540	COG0776	regulation of translation
BH695_RS18545	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BH695_RS18560	COG0095	Lipoate-protein ligase
BH695_RS18580	COG1309	transcriptional regulator
BH695_RS18585	COG0116	Belongs to the methyltransferase superfamily
BH695_RS18590	COG0039	L-malate dehydrogenase activity
BH695_RS18605	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BH695_RS18665	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BH695_RS18675	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BH695_RS18680	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BH695_RS18695	COG0514	ATP-dependent DNA helicase (RecQ)
BH695_RS18700	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BH695_RS18820	COG0156	8-amino-7-oxononanoate synthase activity
BH695_RS18855	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BH695_RS18860	COG1231	oxidoreductase activity
BH695_RS18865	COG2234	aminopeptidase activity
BH695_RS18920	COG1672	PFAM Archaeal ATPase
BH695_RS18920	COG2319	Wd-40 repeat
BH695_RS18930	COG0457	Tetratricopeptide repeat
BH695_RS18930	COG0463	Glycosyl transferase, family 2
BH695_RS18965	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BH695_RS18970	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BH695_RS18980	COG2308	Evidence 4 Homologs of previously reported genes of
BH695_RS19030	COG3659	wide pore channel activity
BH695_RS19065	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BH695_RS19085	COG0640	Transcriptional regulator
BH695_RS19095	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BH695_RS19115	COG0542	response to heat
BH695_RS19145	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BH695_RS19185	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
BH695_RS19195	COG0751	glycine-tRNA ligase activity
BH695_RS19215	COG0784	Response regulator, receiver
BH695_RS19215	COG2205	protein histidine kinase activity
BH695_RS19220	COG1605	Chorismate mutase
BH695_RS19220	COG0077	Prephenate dehydratase
BH695_RS19235	COG0589	response to stress
BH695_RS19240	COG0681	Belongs to the peptidase S26 family
BH695_RS19245	COG3956	TIGRFAM MazG family protein
BH695_RS19265	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BH695_RS19275	COG0457	Tetratricopeptide repeat
BH695_RS19285	COG1216	Glycosyl transferase, family 2
BH695_RS19295	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BH695_RS19305	COG0463	Glycosyl transferase, family 2
BH695_RS19315	COG1595	DNA-templated transcription, initiation
BH695_RS19335	COG0726	polysaccharide deacetylase
BH695_RS19340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BH695_RS19430	COG1012	belongs to the aldehyde dehydrogenase family
BH695_RS19430	COG1454	alcohol dehydrogenase
BH695_RS19435	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BH695_RS19530	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BH695_RS19550	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BH695_RS19555	COG1333	cytochrome c biogenesis protein
BH695_RS19570	COG0601	transmembrane transport
BH695_RS19595	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BH695_RS19600	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BH695_RS19610	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BH695_RS19625	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BH695_RS19635	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BH695_RS19640	COG4956	integral membrane protein (PIN domain superfamily)
BH695_RS19650	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BH695_RS19665	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BH695_RS19675	COG0408	coproporphyrinogen oxidase activity
BH695_RS19680	COG0037	tRNA processing
BH695_RS19685	COG0210	DNA helicase
BH695_RS19700	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BH695_RS19730	COG1598	PFAM Uncharacterised protein family UPF0150
BH695_RS19780	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BH695_RS19790	COG0445	tRNA wobble uridine modification
BH695_RS19800	COG2319	Wd-40 repeat
BH695_RS19800	COG3903	Transcriptional regulator
BH695_RS19825	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BH695_RS19895	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BH695_RS19940	COG0137	argininosuccinate synthase activity
BH695_RS19945	COG5002	protein histidine kinase activity
BH695_RS19960	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BH695_RS19965	COG1357	PFAM Pentapeptide repeats (8 copies)
BH695_RS19985	COG3118	belongs to the thioredoxin family
BH695_RS19995	COG3411	Ferredoxin
BH695_RS20005	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BH695_RS20030	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BH695_RS20045	COG0110	maltose O-acetyltransferase activity
BH695_RS20110	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BH695_RS20140	COG1294	oxidase, subunit
BH695_RS20145	COG1271	oxidase subunit
BH695_RS20150	COG0445	tRNA wobble uridine modification
BH695_RS20205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BH695_RS20260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BH695_RS20260	COG1754	DNA topoisomerase type I activity
BH695_RS20280	COG1840	ABC-type Fe3 transport system, periplasmic component
BH695_RS20345	COG0509	glycine decarboxylation via glycine cleavage system
BH695_RS20370	COG1002	Type II restriction enzyme, methylase subunits
BH695_RS20385	COG1496	oxidoreductase activity
BH695_RS20390	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BH695_RS20405	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BH695_RS20425	COG3854	ATPases associated with a variety of cellular activities
BH695_RS20435	COG0561	phosphatase activity
BH695_RS20440	COG0412	Dienelactone hydrolase
BH695_RS20445	COG0539	negative regulation of cytoplasmic translation
BH695_RS20455	COG2226	methyltransferase
BH695_RS20460	COG2084	Dehydrogenase
BH695_RS20480	COG1136	(ABC) transporter
BH695_RS20495	COG3903	Transcriptional regulator
BH695_RS20495	COG2319	Wd-40 repeat
BH695_RS20510	COG0072	phenylalanine-tRNA ligase activity
BH695_RS20510	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BH695_RS20540	COG1127	ABC transporter
BH695_RS20550	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BH695_RS20680	COG0728	peptidoglycan biosynthetic process
BH695_RS20690	COG0124	histidyl-tRNA synthetase
BH695_RS20695	COG2217	Heavy metal translocating P-type atpase
BH695_RS20730	COG0148	phosphopyruvate hydratase activity
BH695_RS20750	COG1959	2 iron, 2 sulfur cluster binding
BH695_RS20760	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BH695_RS20805	COG1598	PFAM Uncharacterised protein family UPF0150
BH695_RS20840	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BH695_RS20910	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BH695_RS20960	COG0668	transmembrane transport
BH695_RS20965	COG2010	Cytochrome c
BH695_RS21040	COG0010	Belongs to the arginase family
BH695_RS21050	COG2442	InterPro IPR007367
BH695_RS21070	COG0010	Belongs to the arginase family
BH695_RS21110	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BH695_RS21115	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BH695_RS21120	COG0019	diaminopimelate decarboxylase activity
BH695_RS21125	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BH695_RS21145	COG0359	binds to the 23S rRNA
BH695_RS21170	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BH695_RS21175	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BH695_RS21180	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BH695_RS21195	COG0825	malonyl-CoA metabolic process
BH695_RS21200	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BH695_RS21205	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BH695_RS21205	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BH695_RS21215	COG0419	ATPase involved in DNA repair
BH695_RS21220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BH695_RS21225	COG1420	regulation of RNA biosynthetic process
BH695_RS21235	COG1575	Belongs to the MenA family. Type 1 subfamily
BH695_RS21250	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BH695_RS21270	COG0612	Peptidase, M16
BH695_RS21290	COG0640	Transcriptional regulator
BH695_RS21295	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BH695_RS21300	COG0431	NADPH-dependent FMN reductase
BH695_RS21305	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BH695_RS21325	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BH695_RS21330	COG2124	cytochrome p450
BH695_RS21335	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BH695_RS21360	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BH695_RS21390	COG3629	intracellular signal transduction
BH695_RS21390	COG3903	Transcriptional regulator
BH695_RS21500	COG0589	response to stress
BH695_RS21515	COG0482	sulfurtransferase activity
BH695_RS21520	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BH695_RS21530	COG1715	Restriction endonuclease
BH695_RS21535	COG4067	protein conserved in archaea
BH695_RS21535	COG0189	ligase activity
BH695_RS21575	COG0028	Belongs to the TPP enzyme family
BH695_RS21595	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
BH695_RS21600	COG0778	Nitroreductase
BH695_RS21625	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BH695_RS21635	COG0517	IMP dehydrogenase activity
BH695_RS21635	COG1994	Peptidase M50
BH695_RS21640	COG0632	four-way junction helicase activity
BH695_RS21660	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BH695_RS21670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BH695_RS21690	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BH695_RS21695	COG0003	Pfam Anion-transporting ATPase
BH695_RS21710	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BH695_RS21720	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BH695_RS21750	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BH695_RS21765	COG2226	methyltransferase
BH695_RS21805	COG4178	(ABC) transporter
BH695_RS21830	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BH695_RS21845	COG0438	transferase activity, transferring glycosyl groups
BH695_RS21860	COG1672	PFAM Archaeal ATPase
BH695_RS21860	COG2319	Wd-40 repeat
BH695_RS21865	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BH695_RS21870	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BH695_RS21875	COG1122	ATPase activity
BH695_RS21880	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BH695_RS21885	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BH695_RS21930	COG2211	Major facilitator Superfamily
BH695_RS21960	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
BH695_RS21970	COG0463	Glycosyl transferase, family 2
BH695_RS22000	COG0189	ligase activity
BH695_RS22005	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BH695_RS22020	COG0762	integral membrane protein
BH695_RS22065	COG1090	epimerase
BH695_RS22075	COG0515	serine threonine protein kinase
BH695_RS22090	COG2003	Belongs to the UPF0758 family
BH695_RS22095	COG0436	Aminotransferase
BH695_RS22100	COG0277	FAD linked oxidase domain protein
BH695_RS22105	COG0247	lactate metabolic process
BH695_RS22110	COG0460	homoserine dehydrogenase
BH695_RS22130	COG3659	wide pore channel activity
BH695_RS22140	COG1797	cobyrinic acid a,c-diamide synthase activity
BH695_RS22150	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BH695_RS22155	COG2081	HI0933 family
BH695_RS22175	COG0559	Belongs to the binding-protein-dependent transport system permease family
BH695_RS22195	COG2119	membrane
BH695_RS22205	COG0297	glycogen (starch) synthase activity
BH695_RS22215	COG0163	prenyltransferase activity
BH695_RS22230	COG5001	Diguanylate cyclase
BH695_RS22230	COG4251	negative regulation of phosphorylation
BH695_RS22230	COG3706	GGDEF domain
BH695_RS22230	COG2203	Gaf domain
BH695_RS22235	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BH695_RS22240	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BH695_RS22260	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BH695_RS22270	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BH695_RS22275	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BH695_RS22280	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
BH695_RS22290	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BH695_RS22295	COG1850	ribulose-bisphosphate carboxylase activity
BH695_RS22305	COG4451	ribulose bisphosphate carboxylase, small
BH695_RS22330	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BH695_RS22345	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BH695_RS22350	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BH695_RS22355	COG0358	DNA primase activity
BH695_RS22365	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BH695_RS22385	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BH695_RS22390	COG0052	Belongs to the universal ribosomal protein uS2 family
BH695_RS22395	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BH695_RS22400	COG1657	PFAM Prenyltransferase squalene oxidase
BH695_RS22460	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BH695_RS22465	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BH695_RS22530	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BH695_RS22540	COG1132	(ABC) transporter
BH695_RS22565	COG1598	PFAM Uncharacterised protein family UPF0150
BH695_RS22570	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BH695_RS22580	COG2188	Transcriptional regulator
BH695_RS22700	COG1598	PFAM Uncharacterised protein family UPF0150
BH695_RS22710	COG1121	(ABC) transporter
BH695_RS22725	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BH695_RS22740	COG0438	transferase activity, transferring glycosyl groups
BH695_RS22750	COG1408	metallophosphoesterase
BH695_RS22755	COG0436	Aminotransferase
BH695_RS22775	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BH695_RS22790	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BH695_RS22795	COG0459	protein refolding
BH695_RS22815	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BH695_RS22825	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BH695_RS22850	COG0463	Glycosyl transferase, family 2
BH695_RS22865	COG1215	transferase activity, transferring glycosyl groups
BH695_RS22870	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BH695_RS22875	COG0431	NADPH-dependent FMN reductase
BH695_RS22900	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BH695_RS22905	COG0750	zinc metalloprotease
BH695_RS22935	COG0271	Belongs to the BolA IbaG family
BH695_RS22975	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BH695_RS22990	COG4636	protein conserved in cyanobacteria
BH695_RS22995	COG4636	protein conserved in cyanobacteria
BH695_RS23000	COG1022	Amp-dependent synthetase and ligase
BH695_RS23015	COG2319	Wd-40 repeat
BH695_RS23025	COG0489	protein tyrosine kinase activity
BH695_RS23060	COG0746	molybdenum cofactor guanylyltransferase activity
BH695_RS23065	COG0484	heat shock protein binding
BH695_RS23070	COG0735	belongs to the Fur family
BH695_RS23075	COG2166	iron-sulfur cluster assembly
BH695_RS23080	COG2337	Toxic component of a toxin-antitoxin (TA) module
BH695_RS23115	COG1289	transmembrane transporter activity
BH695_RS23125	COG0066	3-isopropylmalate dehydratase activity
BH695_RS23130	COG2226	methyltransferase
BH695_RS23175	COG3657	addiction module killer protein
BH695_RS23200	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BH695_RS23240	COG1132	(ABC) transporter
BH695_RS23245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BH695_RS23250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BH695_RS23255	COG1116	anion transmembrane transporter activity
BH695_RS23255	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BH695_RS23260	COG1116	anion transmembrane transporter activity
BH695_RS23270	COG2022	thiamine diphosphate biosynthetic process
BH695_RS23270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BH695_RS23285	COG3657	addiction module killer protein
BH695_RS23295	COG0405	Gamma-glutamyltransferase
BH695_RS23300	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BH695_RS23310	COG1028	Short-chain dehydrogenase reductase Sdr
BH695_RS23315	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BH695_RS23330	COG5002	protein histidine kinase activity
BH695_RS23365	COG1741	Belongs to the pirin family
BH695_RS23380	COG1562	ergosterol biosynthetic process
BH695_RS23385	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BH695_RS23385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BH695_RS23395	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BH695_RS23400	COG0471	metal ion transport
BH695_RS23400	COG3273	potassium ion transport
BH695_RS23420	COG4581	dead DEAH box helicase
BH695_RS23445	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BH695_RS23455	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BH695_RS23475	COG0824	Thioesterase
BH695_RS23485	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BH695_RS23515	COG0586	Pfam SNARE associated Golgi protein
BH695_RS23520	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BH695_RS23530	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BH695_RS23535	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BH695_RS23550	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BH695_RS23555	COG2304	oxidoreductase activity
BH695_RS23570	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BH695_RS23585	COG0571	ribonuclease III activity
BH695_RS23605	COG2205	protein histidine kinase activity
BH695_RS23610	COG1543	Belongs to the glycosyl hydrolase 57 family
BH695_RS23625	COG0515	serine threonine protein kinase
BH695_RS23650	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BH695_RS23655	COG4991	sh3 domain protein
BH695_RS23655	COG0860	N-Acetylmuramoyl-L-alanine amidase
BH695_RS23655	COG3103	Sh3 type 3 domain protein
BH695_RS23660	COG0857	belongs to the CobB CobQ family
BH695_RS23660	COG0280	phosphate acetyltransferase
BH695_RS23750	COG3321	synthase
BH695_RS23750	COG1028	Short-chain dehydrogenase reductase Sdr
BH695_RS23750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BH695_RS23750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BH695_RS23750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BH695_RS23755	COG1845	cytochrome c oxidase, subunit III
BH695_RS23760	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BH695_RS23765	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BH695_RS23770	COG1612	heme a metabolic process
BH695_RS23775	COG0109	protoheme IX farnesyltransferase activity
BH695_RS23780	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BH695_RS23785	COG0242	peptide deformylase activity
BH695_RS23820	COG4974	Belongs to the 'phage' integrase family
BH695_RS23865	COG0242	peptide deformylase activity
BH695_RS23880	COG0792	nuclease activity
BH695_RS23900	COG0392	lysyltransferase activity
BH695_RS23915	COG2319	Wd-40 repeat
BH695_RS23915	COG1672	PFAM Archaeal ATPase
BH695_RS23925	COG4991	sh3 domain protein
BH695_RS23925	COG0515	serine threonine protein kinase
BH695_RS23925	COG3064	Membrane
BH695_RS23965	COG0598	Magnesium transport protein CorA
BH695_RS23975	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BH695_RS23980	COG1012	belongs to the aldehyde dehydrogenase family
BH695_RS23985	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BH695_RS24000	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BH695_RS24010	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BH695_RS24015	COG0492	ferredoxin-NADP+ reductase activity
BH695_RS24050	COG1131	(ABC) transporter
BH695_RS24070	COG0501	Belongs to the peptidase M48B family
BH695_RS24075	COG0463	Glycosyl transferase, family 2
BH695_RS24075	COG1216	Glycosyl transferase, family 2
BH695_RS24085	COG4172	Belongs to the ABC transporter superfamily
BH695_RS24095	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BH695_RS24105	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BH695_RS24115	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BH695_RS24125	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BH695_RS24130	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BH695_RS24135	COG5322	oxidoreductase activity
BH695_RS24160	COG0788	formyltetrahydrofolate deformylase activity
BH695_RS24180	COG0628	permease
BH695_RS24195	COG0107	imidazoleglycerol-phosphate synthase activity
BH695_RS24200	COG2255	four-way junction helicase activity
BH695_RS24210	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BH695_RS24215	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BH695_RS24225	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BH695_RS24240	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BH695_RS24255	COG1672	PFAM Archaeal ATPase
BH695_RS24255	COG2319	Wd-40 repeat
BH695_RS24285	COG3266	domain, Protein
BH695_RS24285	COG0515	serine threonine protein kinase
BH695_RS24305	COG1162	GTPase activity
BH695_RS24315	COG0484	heat shock protein binding
BH695_RS24320	COG0443	Heat shock 70 kDa protein
BH695_RS24325	COG1064	alcohol dehydrogenase
BH695_RS24350	COG0181	hydroxymethylbilane synthase activity
BH695_RS24355	COG0730	response to heat
BH695_RS24360	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BH695_RS24375	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BH695_RS24380	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BH695_RS24385	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BH695_RS24400	COG0123	including yeast histone deacetylase and acetoin utilization protein
BH695_RS24405	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
BH695_RS24420	COG1598	PFAM Uncharacterised protein family UPF0150
BH695_RS24455	COG0484	heat shock protein binding
BH695_RS24460	COG0398	Pfam SNARE associated Golgi protein
BH695_RS24470	COG3179	chitinase
BH695_RS24530	COG0583	DNA-binding transcription factor activity
BH695_RS24535	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BH695_RS24540	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BH695_RS24545	COG2226	methyltransferase
BH695_RS24555	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BH695_RS24570	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BH695_RS24595	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BH695_RS24605	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BH695_RS24615	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BH695_RS24620	COG0719	Fe-S assembly protein
BH695_RS24625	COG0396	ATPase activity
BH695_RS24630	COG0719	Fe-S assembly protein
BH695_RS24650	COG0297	glycogen (starch) synthase activity
BH695_RS24655	COG0151	Belongs to the GarS family
BH695_RS24660	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BH695_RS24675	COG1981	membrane
BH695_RS24690	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BH695_RS24695	COG2954	triphosphatase activity
BH695_RS24710	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BH695_RS24720	COG1178	ABC-type Fe3 transport system permease component
BH695_RS24730	COG0512	Glutamine amidotransferase of anthranilate synthase
BH695_RS24735	COG1357	PFAM Pentapeptide repeats (8 copies)
BH695_RS24740	COG1316	TRANSCRIPTIONal
BH695_RS24745	COG0791	NLP P60 protein
BH695_RS24755	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BH695_RS24760	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BH695_RS24770	COG0745	RESPONSE REGULATOR receiver
BH695_RS24775	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BH695_RS24780	COG0779	Required for maturation of 30S ribosomal subunits
BH695_RS24785	COG0195	Participates in both transcription termination and antitermination
BH695_RS24795	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BH695_RS24795	COG3170	Tfp pilus assembly protein FimV
BH695_RS24805	COG3338	carbonate dehydratase activity
BH695_RS24810	COG0415	Belongs to the DNA photolyase family
BH695_RS24860	COG0235	Class ii aldolase
BH695_RS24900	COG0343	queuine tRNA-ribosyltransferase activity
BH695_RS24925	COG0154	amidase activity
BH695_RS24940	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BH695_RS24945	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BH695_RS24950	COG0643	Histidine kinase
BH695_RS24950	COG2198	Histidine kinase
BH695_RS24970	COG1247	-acetyltransferase
BH695_RS24985	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BH695_RS25000	COG3429	Glucose-6-phosphate dehydrogenase subunit
BH695_RS25000	COG3409	Peptidoglycan-binding domain 1 protein
BH695_RS25005	COG4636	protein conserved in cyanobacteria
BH695_RS25010	COG0126	phosphoglycerate kinase activity
BH695_RS25015	COG0589	response to stress
BH695_RS25040	COG2239	Acts as a magnesium transporter
BH695_RS25045	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BH695_RS25070	COG1940	carbohydrate kinase activity
BH695_RS25090	COG0863	Belongs to the N(4) N(6)-methyltransferase family
BH695_RS25095	COG0205	6-phosphofructokinase activity
BH695_RS25100	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BH695_RS25120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BH695_RS25125	COG0704	Plays a role in the regulation of phosphate uptake
BH695_RS25130	COG5002	protein histidine kinase activity
BH695_RS25135	COG0745	RESPONSE REGULATOR receiver
BH695_RS25150	COG0277	FAD linked oxidase domain protein
BH695_RS25165	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BH695_RS25170	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BH695_RS25175	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BH695_RS25180	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BH695_RS25185	COG0202	RNA polymerase activity
BH695_RS25190	COG0203	ribosomal protein L17
BH695_RS25195	COG0101	tRNA pseudouridine synthase activity
BH695_RS25200	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BH695_RS25205	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BH695_RS25210	COG0254	rRNA binding
BH695_RS25230	COG1131	(ABC) transporter
BH695_RS25255	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BH695_RS25300	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BH695_RS25305	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BH695_RS25320	COG0134	indole-3-glycerol-phosphate synthase activity