locus-tag	class	description
DCS86_RS00015	COG0539	negative regulation of cytoplasmic translation
DCS86_RS00020	COG0494	nUDIX hydrolase
DCS86_RS00025	COG2837	iron assimilation
DCS86_RS00030	COG2822	iron ion transport
DCS86_RS00035	COG0672	)-iron permease
DCS86_RS00045	COG1012	belongs to the aldehyde dehydrogenase family
DCS86_RS00050	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DCS86_RS00055	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DCS86_RS00055	COG0237	dephospho-CoA kinase activity
DCS86_RS00060	COG1764	response to oxidative stress
DCS86_RS00065	COG0556	nucleotide-excision repair
DCS86_RS00090	COG0322	excinuclease ABC activity
DCS86_RS00095	COG1660	Displays ATPase and GTPase activities
DCS86_RS00105	COG1481	regulation of sporulation
DCS86_RS00110	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DCS86_RS00115	COG0126	phosphoglycerate kinase activity
DCS86_RS00120	COG0149	triose-phosphate isomerase activity
DCS86_RS00125	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DCS86_RS00135	COG0363	glucosamine-6-phosphate deaminase activity
DCS86_RS00150	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DCS86_RS00160	COG0109	protoheme IX farnesyltransferase activity
DCS86_RS00180	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DCS86_RS00195	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DCS86_RS00205	COG1160	GTP binding
DCS86_RS00210	COG1732	Glycine betaine
DCS86_RS00215	COG1174	glycine betaine transport
DCS86_RS00220	COG1174	glycine betaine transport
DCS86_RS00225	COG0517	IMP dehydrogenase activity
DCS86_RS00225	COG1125	glycine betaine transport
DCS86_RS00230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DCS86_RS00235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DCS86_RS00245	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DCS86_RS00245	COG2080	2 iron, 2 sulfur cluster binding
DCS86_RS00255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DCS86_RS00275	COG0402	S-adenosylhomocysteine deaminase activity
DCS86_RS00355	COG2132	Multicopper oxidase
DCS86_RS00360	COG2217	Heavy metal translocating P-type atpase
DCS86_RS00405	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DCS86_RS00440	COG2197	response regulator
DCS86_RS00455	COG1136	(ABC) transporter
DCS86_RS00480	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DCS86_RS00490	COG1435	thymidine kinase activity
DCS86_RS00500	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DCS86_RS00505	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DCS86_RS00515	COG3253	May function as heme-dependent peroxidase
DCS86_RS00520	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DCS86_RS00525	COG0181	hydroxymethylbilane synthase activity
DCS86_RS00535	COG0113	porphobilinogen synthase activity
DCS86_RS00540	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DCS86_RS00555	COG2264	protein methyltransferase activity
DCS86_RS00575	COG0328	RNA-DNA hybrid ribonuclease activity
DCS86_RS00590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DCS86_RS00635	COG0596	Alpha beta hydrolase
DCS86_RS00640	COG0406	alpha-ribazole phosphatase activity
DCS86_RS00660	COG4941	Belongs to the sigma-70 factor family
DCS86_RS00730	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DCS86_RS00800	COG0180	Tryptophanyl-tRNA synthetase
DCS86_RS00815	COG0710	3-dehydroquinate dehydratase activity
DCS86_RS00850	COG2378	regulation of single-species biofilm formation
DCS86_RS00875	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DCS86_RS00880	COG0140	phosphoribosyl-ATP diphosphatase activity
DCS86_RS00885	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DCS86_RS00890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DCS86_RS00900	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DCS86_RS00910	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DCS86_RS00915	COG1011	Hydrolase
DCS86_RS00920	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DCS86_RS00940	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DCS86_RS00950	COG1758	RNA polymerase activity
DCS86_RS00955	COG0194	GDP metabolic process
DCS86_RS00960	COG0194	GDP metabolic process
DCS86_RS00970	COG0284	orotidine-5'-phosphate decarboxylase activity
DCS86_RS00975	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DCS86_RS00990	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DCS86_RS00995	COG0540	Belongs to the ATCase OTCase family
DCS86_RS01000	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DCS86_RS01005	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DCS86_RS01010	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DCS86_RS01025	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DCS86_RS01030	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DCS86_RS01035	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DCS86_RS01045	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DCS86_RS01055	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DCS86_RS01075	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DCS86_RS01085	COG2409	Drug exporters of the RND superfamily
DCS86_RS01095	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DCS86_RS01100	COG0436	Aminotransferase
DCS86_RS01110	COG0124	histidyl-tRNA synthetase
DCS86_RS01115	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DCS86_RS01120	COG1196	nuclear chromosome segregation
DCS86_RS01135	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DCS86_RS01140	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DCS86_RS01145	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DCS86_RS01155	COG2255	four-way junction helicase activity
DCS86_RS01160	COG0632	four-way junction helicase activity
DCS86_RS01165	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DCS86_RS01170	COG0217	transcriptional regulatory protein
DCS86_RS01175	COG0494	nUDIX hydrolase
DCS86_RS01190	COG0438	transferase activity, transferring glycosyl groups
DCS86_RS01195	COG1560	Kdo2-lipid A biosynthetic process
DCS86_RS01200	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DCS86_RS01210	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DCS86_RS01220	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DCS86_RS01245	COG1643	Atp-dependent helicase
DCS86_RS01310	COG0183	Belongs to the thiolase family
DCS86_RS01315	COG1024	Enoyl-CoA hydratase
DCS86_RS01315	COG1250	3-hydroxyacyl-CoA dehydrogenase
DCS86_RS01320	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DCS86_RS01375	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DCS86_RS01385	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DCS86_RS01390	COG1609	Transcriptional regulator
DCS86_RS01395	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DCS86_RS01405	COG1914	H( )-stimulated, divalent metal cation uptake system
DCS86_RS01410	COG1404	Belongs to the peptidase S8 family
DCS86_RS01420	COG0531	amino acid
DCS86_RS01425	COG0569	domain protein
DCS86_RS01450	COG0756	dUTP diphosphatase activity
DCS86_RS01490	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DCS86_RS01495	COG0456	acetyltransferase
DCS86_RS01500	COG0187	DNA topoisomerase II activity
DCS86_RS01535	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DCS86_RS01540	COG0509	glycine decarboxylation via glycine cleavage system
DCS86_RS01545	COG0589	response to stress
DCS86_RS01555	COG0142	geranyltranstransferase activity
DCS86_RS01565	COG2815	serine threonine protein kinase
DCS86_RS01565	COG0515	serine threonine protein kinase
DCS86_RS01570	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DCS86_RS01575	COG0205	6-phosphofructokinase activity
DCS86_RS01590	COG1940	carbohydrate kinase activity
DCS86_RS01610	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DCS86_RS01620	COG1845	cytochrome c oxidase, subunit III
DCS86_RS01630	COG0723	plastoquinol--plastocyanin reductase activity
DCS86_RS01635	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DCS86_RS01655	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DCS86_RS01660	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DCS86_RS01665	COG0545	Peptidyl-prolyl cis-trans isomerase
DCS86_RS01690	COG0167	dihydroorotate dehydrogenase activity
DCS86_RS01705	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DCS86_RS01710	COG0508	dehydrogenase complex catalyzes the overall conversion of
DCS86_RS01715	COG1090	epimerase
DCS86_RS01735	COG2011	ABC-type metal ion transport system permease component
DCS86_RS01740	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DCS86_RS01745	COG1464	Belongs to the NlpA lipoprotein family
DCS86_RS01770	COG2197	response regulator
DCS86_RS01775	COG4946	Tricorn protease homolog
DCS86_RS01775	COG0823	Involved in the tonB-independent uptake of proteins
DCS86_RS01775	COG1506	peptidase
DCS86_RS01785	COG1222	aaa ATPase
DCS86_RS01905	COG1119	ATPase activity
DCS86_RS01920	COG0297	glycogen (starch) synthase activity
DCS86_RS01940	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DCS86_RS01945	COG1028	Short-chain dehydrogenase reductase Sdr
DCS86_RS01975	COG0488	(ABC) transporter
DCS86_RS01980	COG1268	BioY protein
DCS86_RS01995	COG3537	Alpha-1,2-mannosidase
DCS86_RS02000	COG0446	pyridine nucleotide-disulphide oxidoreductase
DCS86_RS02035	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DCS86_RS02055	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DCS86_RS02060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DCS86_RS02140	COG0583	DNA-binding transcription factor activity
DCS86_RS02145	COG0358	DNA primase activity
DCS86_RS02185	COG2826	transposase and inactivated derivatives, IS30 family
DCS86_RS02230	COG1621	beta-fructofuranosidase activity
DCS86_RS02235	COG1621	beta-fructofuranosidase activity
DCS86_RS02250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DCS86_RS02255	COG0601	transmembrane transport
DCS86_RS02260	COG0747	negative chemotaxis
DCS86_RS02265	COG1609	Transcriptional regulator
DCS86_RS02270	COG0444	Belongs to the ABC transporter superfamily
DCS86_RS02275	COG4608	Belongs to the ABC transporter superfamily
DCS86_RS02295	COG0366	Alpha amylase catalytic
DCS86_RS02300	COG0366	Alpha amylase catalytic
DCS86_RS02305	COG0366	Alpha amylase catalytic
DCS86_RS02310	COG3833	ABC-type maltose transport systems, permease component
DCS86_RS02315	COG1175	transmembrane transport
DCS86_RS02345	COG0423	glycine-tRNA ligase activity
DCS86_RS02350	COG3443	Belongs to the bacterial solute-binding protein 9 family
DCS86_RS02350	COG0803	Belongs to the bacterial solute-binding protein 9 family
DCS86_RS02355	COG1121	(ABC) transporter
DCS86_RS02360	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DCS86_RS02380	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DCS86_RS02385	COG1381	Involved in DNA repair and RecF pathway recombination
DCS86_RS02395	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DCS86_RS02405	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DCS86_RS02410	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DCS86_RS02420	COG0484	heat shock protein binding
DCS86_RS02425	COG1420	regulation of RNA biosynthetic process
DCS86_RS02445	COG0481	GTPase activity
DCS86_RS02460	COG1305	Transglutaminase-like
DCS86_RS02470	COG2308	Evidence 4 Homologs of previously reported genes of
DCS86_RS02480	COG0268	Binds directly to 16S ribosomal RNA
DCS86_RS02495	COG0658	competence protein
DCS86_RS02495	COG2333	competence protein COMEC
DCS86_RS02505	COG0433	COG0433 Predicted ATPase
DCS86_RS02510	COG0137	argininosuccinate synthase activity
DCS86_RS02525	COG2860	membrane
DCS86_RS02540	COG1846	Transcriptional regulator
DCS86_RS02545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DCS86_RS02560	COG1253	flavin adenine dinucleotide binding
DCS86_RS02590	COG1396	sequence-specific DNA binding
DCS86_RS02595	COG2515	1-aminocyclopropane-1-carboxylate deaminase
DCS86_RS02600	COG0697	spore germination
DCS86_RS02620	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DCS86_RS02625	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DCS86_RS02635	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DCS86_RS02650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DCS86_RS02655	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DCS86_RS02660	COG1120	ATPase activity
DCS86_RS02700	COG0110	maltose O-acetyltransferase activity
DCS86_RS02730	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DCS86_RS02740	COG2826	transposase and inactivated derivatives, IS30 family
DCS86_RS02775	COG1431	PFAM Stem cell self-renewal protein Piwi
DCS86_RS02875	COG1475	DNA binding
DCS86_RS02880	COG0739	heme binding
DCS86_RS02880	COG0741	lytic transglycosylase activity
DCS86_RS02880	COG1196	nuclear chromosome segregation
DCS86_RS02935	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DCS86_RS02940	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DCS86_RS02945	COG0798	PFAM Bile acid sodium symporter
DCS86_RS02950	COG3118	belongs to the thioredoxin family
DCS86_RS02955	COG0492	ferredoxin-NADP+ reductase activity
DCS86_RS02960	COG0640	Transcriptional regulator
DCS86_RS03055	COG0799	negative regulation of ribosome biogenesis
DCS86_RS03065	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DCS86_RS03080	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DCS86_RS03085	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DCS86_RS03090	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DCS86_RS03095	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DCS86_RS03105	COG1530	ribonuclease E activity
DCS86_RS03110	COG1271	oxidase subunit
DCS86_RS03115	COG1294	oxidase, subunit
DCS86_RS03120	COG4988	ABC transporter
DCS86_RS03125	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DCS86_RS03140	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DCS86_RS03145	COG0571	ribonuclease III activity
DCS86_RS03150	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DCS86_RS03165	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DCS86_RS03175	COG0742	ribosomal rna small subunit methyltransferase
DCS86_RS03185	COG4133	protoheme IX ABC transporter activity
DCS86_RS03195	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DCS86_RS03215	COG1181	Belongs to the D-alanine--D-alanine ligase family
DCS86_RS03230	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DCS86_RS03260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DCS86_RS03265	COG0601	transmembrane transport
DCS86_RS03270	COG0747	negative chemotaxis
DCS86_RS03275	COG2409	Drug exporters of the RND superfamily
DCS86_RS03285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DCS86_RS03290	COG2755	lipolytic protein G-D-S-L family
DCS86_RS03290	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DCS86_RS03300	COG0066	3-isopropylmalate dehydratase activity
DCS86_RS03305	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DCS86_RS03320	COG0745	RESPONSE REGULATOR receiver
DCS86_RS03345	COG1725	Transcriptional regulator
DCS86_RS03350	COG1074	ATP-dependent DNA helicase activity
DCS86_RS03355	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DCS86_RS03375	COG1011	Hydrolase
DCS86_RS03380	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DCS86_RS03405	COG1780	Probably involved in ribonucleotide reductase function
DCS86_RS03420	COG1739	Uncharacterized protein family UPF0029
DCS86_RS03425	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
DCS86_RS03430	COG0475	glutathione-regulated potassium exporter activity
DCS86_RS03430	COG0569	domain protein
DCS86_RS03440	COG0747	negative chemotaxis
DCS86_RS03460	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DCS86_RS03470	COG2188	Transcriptional regulator
DCS86_RS03475	COG2190	(PTS) system
DCS86_RS03475	COG1263	PTS System
DCS86_RS03475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DCS86_RS03485	COG0363	glucosamine-6-phosphate deaminase activity
DCS86_RS03490	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DCS86_RS03505	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DCS86_RS03540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DCS86_RS03545	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DCS86_RS03550	COG0473	3-isopropylmalate dehydrogenase activity
DCS86_RS03565	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DCS86_RS03570	COG0440	acetolactate synthase activity
DCS86_RS03605	COG0129	dihydroxy-acid dehydratase activity
DCS86_RS03610	COG0129	dihydroxy-acid dehydratase activity
DCS86_RS03615	COG1321	iron dependent repressor
DCS86_RS03620	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DCS86_RS03625	COG0154	amidase activity
DCS86_RS03630	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DCS86_RS03640	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DCS86_RS03655	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DCS86_RS03665	COG2351	hydroxyisourate hydrolase activity
DCS86_RS03670	COG2233	PERMEase
DCS86_RS03680	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DCS86_RS03685	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DCS86_RS03700	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DCS86_RS03710	COG0482	sulfurtransferase activity
DCS86_RS03725	COG1131	(ABC) transporter
DCS86_RS03755	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DCS86_RS03775	COG0205	6-phosphofructokinase activity
DCS86_RS03780	COG0366	Alpha amylase catalytic
DCS86_RS03790	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DCS86_RS03840	COG0488	(ABC) transporter
DCS86_RS03855	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
DCS86_RS03870	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DCS86_RS03875	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DCS86_RS03880	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DCS86_RS03885	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DCS86_RS03890	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DCS86_RS03895	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DCS86_RS03900	COG0356	it plays a direct role in the translocation of protons across the membrane
DCS86_RS03910	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DCS86_RS03925	COG2890	protein-(glutamine-N5) methyltransferase activity
DCS86_RS03930	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DCS86_RS03935	COG0254	rRNA binding
DCS86_RS03950	COG0083	homoserine kinase activity
DCS86_RS03955	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DCS86_RS03960	COG0460	homoserine dehydrogenase
DCS86_RS03965	COG0019	diaminopimelate decarboxylase activity
DCS86_RS03995	COG0745	RESPONSE REGULATOR receiver
DCS86_RS04000	COG2205	protein histidine kinase activity
DCS86_RS04005	COG0508	dehydrogenase complex catalyzes the overall conversion of
DCS86_RS04005	COG0567	Dehydrogenase, E1 component
DCS86_RS04025	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DCS86_RS04035	COG1595	DNA-templated transcription, initiation
DCS86_RS04045	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DCS86_RS04050	COG1162	GTPase activity
DCS86_RS04055	COG0483	inositol monophosphate 1-phosphatase activity
DCS86_RS04065	COG0489	protein tyrosine kinase activity
DCS86_RS04095	COG0653	protein targeting
DCS86_RS04110	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DCS86_RS04120	COG5401	PFAM Sporulation and spore germination
DCS86_RS04125	COG5002	protein histidine kinase activity
DCS86_RS04125	COG5000	phosphorelay sensor kinase activity
DCS86_RS04130	COG0745	RESPONSE REGULATOR receiver
DCS86_RS04140	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DCS86_RS04145	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DCS86_RS04150	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DCS86_RS04155	COG2835	tetraacyldisaccharide 4'-kinase activity
DCS86_RS04195	COG1316	TRANSCRIPTIONal
DCS86_RS04210	COG0463	Glycosyl transferase, family 2
DCS86_RS04225	COG2755	lipolytic protein G-D-S-L family
DCS86_RS04225	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DCS86_RS04250	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DCS86_RS04290	COG0463	Glycosyl transferase, family 2
DCS86_RS04310	COG1088	dTDP-glucose 4,6-dehydratase activity
DCS86_RS04315	COG1316	TRANSCRIPTIONal
DCS86_RS04335	COG1216	Glycosyl transferase, family 2
DCS86_RS04355	COG1832	CoA-binding protein
DCS86_RS04370	COG1482	cell wall glycoprotein biosynthetic process
DCS86_RS04390	COG2205	protein histidine kinase activity
DCS86_RS04395	COG0745	RESPONSE REGULATOR receiver
DCS86_RS04410	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DCS86_RS04430	COG0424	maF-like protein
DCS86_RS04435	COG4770	biotin carboxylase activity
DCS86_RS04475	COG2720	vancomycin resistance protein
DCS86_RS04480	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DCS86_RS04490	COG1217	gtp-binding protein TYPA
DCS86_RS04510	COG0601	transmembrane transport
DCS86_RS04515	COG4166	transmembrane transport
DCS86_RS04525	COG1228	amidohydrolase
DCS86_RS04535	COG0436	Aminotransferase
DCS86_RS04555	COG4115	mRNA cleavage
DCS86_RS04590	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DCS86_RS04595	COG0012	GTP binding
DCS86_RS04600	COG1322	Protein conserved in bacteria
DCS86_RS04605	COG1570	exodeoxyribonuclease VII activity
DCS86_RS04610	COG1722	exodeoxyribonuclease VII activity
DCS86_RS04620	COG0288	reversible hydration of carbon dioxide
DCS86_RS04640	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DCS86_RS04645	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DCS86_RS04655	COG2326	polyphosphate kinase activity
DCS86_RS04670	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DCS86_RS04680	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DCS86_RS04685	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DCS86_RS04690	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DCS86_RS04695	COG0058	SHG alpha-glucan phosphorylase activity
DCS86_RS04710	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DCS86_RS04710	COG1796	DNA polymerase
DCS86_RS04720	COG3458	cephalosporin-C deacetylase activity
DCS86_RS04735	COG1131	(ABC) transporter
DCS86_RS04745	COG4585	Histidine kinase
DCS86_RS04750	COG2197	response regulator
DCS86_RS04770	COG1252	NADH dehydrogenase
DCS86_RS04795	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DCS86_RS04815	COG0148	phosphopyruvate hydratase activity
DCS86_RS04825	COG0588	phosphoglycerate mutase activity
DCS86_RS04850	COG0489	protein tyrosine kinase activity
DCS86_RS04860	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DCS86_RS04865	COG3291	Pkd domain containing protein
DCS86_RS04895	COG0076	glutamate decarboxylase activity
DCS86_RS04915	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DCS86_RS04915	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DCS86_RS04920	COG0438	transferase activity, transferring glycosyl groups
DCS86_RS04930	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DCS86_RS04935	COG0193	aminoacyl-tRNA hydrolase activity
DCS86_RS04940	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DCS86_RS05005	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DCS86_RS05035	COG0488	(ABC) transporter
DCS86_RS05055	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DCS86_RS05075	COG0084	hydrolase, TatD family'
DCS86_RS05080	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DCS86_RS05090	COG0436	Aminotransferase
DCS86_RS05095	COG1335	isochorismatase
DCS86_RS05145	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DCS86_RS05145	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DCS86_RS05150	COG1937	Protein conserved in bacteria
DCS86_RS05170	COG2205	protein histidine kinase activity
DCS86_RS05175	COG0745	RESPONSE REGULATOR receiver
DCS86_RS05180	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DCS86_RS05230	COG1609	Transcriptional regulator
DCS86_RS05240	COG1175	transmembrane transport
DCS86_RS05245	COG0395	ABC-type sugar transport system, permease component
DCS86_RS05270	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DCS86_RS05285	COG1970	mechanosensitive ion channel activity
DCS86_RS05300	COG0667	Aldo Keto reductase
DCS86_RS05325	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DCS86_RS05340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DCS86_RS05355	COG1278	Cold shock
DCS86_RS05375	COG2814	Major facilitator Superfamily
DCS86_RS05385	COG1842	Phage shock protein A
DCS86_RS05400	COG0745	RESPONSE REGULATOR receiver
DCS86_RS05405	COG2205	protein histidine kinase activity
DCS86_RS05410	COG5426	von Willebrand factor, type A
DCS86_RS05420	COG0395	ABC-type sugar transport system, permease component
DCS86_RS05425	COG1175	transmembrane transport
DCS86_RS05440	COG0671	phosphoesterase, PA-phosphatase related
DCS86_RS05480	COG0459	protein refolding
DCS86_RS05500	COG4946	Tricorn protease homolog
DCS86_RS05500	COG0823	Involved in the tonB-independent uptake of proteins
DCS86_RS05500	COG1506	peptidase
DCS86_RS05510	COG0579	oxidoreductase
DCS86_RS05525	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DCS86_RS05550	COG1063	alcohol dehydrogenase
DCS86_RS05555	COG0531	amino acid
DCS86_RS05560	COG2160	L-arabinose isomerase activity
DCS86_RS05575	COG1609	Transcriptional regulator
DCS86_RS05580	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DCS86_RS05590	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DCS86_RS05595	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
DCS86_RS05605	COG1194	a g-specific adenine glycosylase
DCS86_RS05615	COG2390	Transcriptional regulator
DCS86_RS05620	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DCS86_RS05625	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DCS86_RS05630	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DCS86_RS05670	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DCS86_RS05675	COG1070	Carbohydrate kinase
DCS86_RS05680	COG2115	Belongs to the xylose isomerase family
DCS86_RS05710	COG1028	Short-chain dehydrogenase reductase Sdr
DCS86_RS05710	COG3347	Dehydrogenase
DCS86_RS05715	COG1028	Short-chain dehydrogenase reductase Sdr
DCS86_RS05720	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DCS86_RS05740	COG1070	Carbohydrate kinase
DCS86_RS05745	COG4952	isomerase
DCS86_RS05755	COG1609	Transcriptional regulator
DCS86_RS05760	COG1609	Transcriptional regulator
DCS86_RS05765	COG1619	proteins homologs of microcin C7 resistance protein MccF
DCS86_RS05770	COG1609	Transcriptional regulator
DCS86_RS05780	COG1175	transmembrane transport
DCS86_RS05785	COG0395	ABC-type sugar transport system, permease component
DCS86_RS05790	COG1472	Belongs to the glycosyl hydrolase 3 family
DCS86_RS05815	COG0395	ABC-type sugar transport system, permease component
DCS86_RS05820	COG4209	transmembrane transport
DCS86_RS05830	COG1609	Transcriptional regulator
DCS86_RS05850	COG1501	Belongs to the glycosyl hydrolase 31 family
DCS86_RS05875	COG0702	epimerase
DCS86_RS05905	COG1609	Transcriptional regulator
DCS86_RS05910	COG1609	Transcriptional regulator
DCS86_RS05920	COG3507	Belongs to the glycosyl hydrolase 43 family
DCS86_RS05935	COG1472	Belongs to the glycosyl hydrolase 3 family
DCS86_RS05940	COG0395	ABC-type sugar transport system, permease component
DCS86_RS05945	COG4209	transmembrane transport
DCS86_RS05970	COG1501	Belongs to the glycosyl hydrolase 31 family
DCS86_RS05980	COG0028	Belongs to the TPP enzyme family
DCS86_RS06010	COG1490	D-aminoacyl-tRNA deacylase activity
DCS86_RS06025	COG0354	folic acid binding
DCS86_RS06030	COG3485	protocatechuate 3,4-dioxygenase
DCS86_RS06035	COG1609	Transcriptional regulator
DCS86_RS06040	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DCS86_RS06055	COG0745	RESPONSE REGULATOR receiver
DCS86_RS06070	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DCS86_RS06090	COG1472	Belongs to the glycosyl hydrolase 3 family
DCS86_RS06100	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DCS86_RS06105	COG0454	-acetyltransferase
DCS86_RS06105	COG0456	acetyltransferase
DCS86_RS06115	COG1305	Transglutaminase-like
DCS86_RS06135	COG1609	Transcriptional regulator
DCS86_RS06150	COG5578	integral membrane protein
DCS86_RS06155	COG0395	ABC-type sugar transport system, permease component
DCS86_RS06160	COG4209	transmembrane transport
DCS86_RS06165	COG1653	transport
DCS86_RS06180	COG1609	Transcriptional regulator
DCS86_RS06195	COG1940	carbohydrate kinase activity
DCS86_RS06195	COG1846	Transcriptional regulator
DCS86_RS06215	COG0395	ABC-type sugar transport system, permease component
DCS86_RS06220	COG4209	transmembrane transport
DCS86_RS06240	COG1609	Transcriptional regulator
DCS86_RS06245	COG4209	transmembrane transport
DCS86_RS06250	COG0395	ABC-type sugar transport system, permease component
DCS86_RS06270	COG0457	Tetratricopeptide repeat
DCS86_RS06290	COG1175	transmembrane transport
DCS86_RS06300	COG1609	Transcriptional regulator
DCS86_RS06305	COG0640	Transcriptional regulator
DCS86_RS06325	COG0673	inositol 2-dehydrogenase activity
DCS86_RS06360	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DCS86_RS06375	COG0513	Belongs to the DEAD box helicase family
DCS86_RS06380	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DCS86_RS06440	COG1012	belongs to the aldehyde dehydrogenase family
DCS86_RS06475	COG1304	FMN binding
DCS86_RS06490	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DCS86_RS06495	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DCS86_RS06515	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DCS86_RS06555	COG1349	DNA-binding transcription factor activity
DCS86_RS06560	COG1162	GTPase activity
DCS86_RS06585	COG0515	serine threonine protein kinase
DCS86_RS06595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DCS86_RS06620	COG0477	Major facilitator Superfamily
DCS86_RS06625	COG0730	response to heat
DCS86_RS06630	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DCS86_RS06645	COG0601	transmembrane transport
DCS86_RS06650	COG0747	negative chemotaxis
DCS86_RS06655	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DCS86_RS06690	COG3425	synthase
DCS86_RS06700	COG0464	growth
DCS86_RS06715	COG1028	Short-chain dehydrogenase reductase Sdr
DCS86_RS06730	COG0318	PFAM AMP-dependent synthetase and ligase
DCS86_RS06735	COG0047	phosphoribosylformylglycinamidine synthase activity
DCS86_RS06740	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DCS86_RS06755	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DCS86_RS06760	COG2814	Major facilitator Superfamily
DCS86_RS06765	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DCS86_RS06800	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DCS86_RS06810	COG0151	Belongs to the GarS family
DCS86_RS06830	COG2252	PERMEase
DCS86_RS06835	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DCS86_RS06850	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DCS86_RS06860	COG0586	Pfam SNARE associated Golgi protein
DCS86_RS06870	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DCS86_RS06875	COG0300	oxidoreductase activity
DCS86_RS06910	COG1609	Transcriptional regulator
DCS86_RS06915	COG3250	beta-galactosidase activity
DCS86_RS06920	COG2814	Major facilitator Superfamily
DCS86_RS06940	COG0494	nUDIX hydrolase
DCS86_RS06950	COG0154	amidase activity
DCS86_RS06975	COG1505	serine-type exopeptidase activity
DCS86_RS06985	COG0702	epimerase
DCS86_RS07015	COG2211	Major facilitator Superfamily
DCS86_RS07020	COG0393	Putative heavy-metal-binding
DCS86_RS07055	COG2190	(PTS) system
DCS86_RS07060	COG1263	PTS System
DCS86_RS07060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DCS86_RS07065	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DCS86_RS07080	COG1522	sequence-specific DNA binding
DCS86_RS07085	COG1966	Carbon starvation protein
DCS86_RS07095	COG1834	amidinotransferase
DCS86_RS07100	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DCS86_RS07125	COG1404	Belongs to the peptidase S8 family
DCS86_RS07130	COG1404	Belongs to the peptidase S8 family
DCS86_RS07150	COG1674	ftsk spoiiie
DCS86_RS07155	COG1305	Transglutaminase-like
DCS86_RS07165	COG0714	Associated with various cellular activities
DCS86_RS07185	COG1793	dna ligase
DCS86_RS07275	COG1028	Short-chain dehydrogenase reductase Sdr
DCS86_RS07280	COG1506	peptidase
DCS86_RS07280	COG0823	Involved in the tonB-independent uptake of proteins
DCS86_RS07295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DCS86_RS07310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DCS86_RS07315	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DCS86_RS07320	COG0431	NADPH-dependent FMN reductase
DCS86_RS07325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DCS86_RS07330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DCS86_RS07345	COG3250	beta-galactosidase activity
DCS86_RS07360	COG2814	Major facilitator Superfamily
DCS86_RS07370	COG3104	oligopeptide transport
DCS86_RS07390	COG2267	carboxylic ester hydrolase activity
DCS86_RS07405	COG1136	(ABC) transporter
DCS86_RS07415	COG2271	Major facilitator Superfamily
DCS86_RS07430	COG0488	(ABC) transporter
DCS86_RS07455	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DCS86_RS07475	COG3012	SEC-C Motif Domain Protein
DCS86_RS07505	COG0693	protein deglycase activity
DCS86_RS07510	COG1295	ribonuclease BN
DCS86_RS07555	COG0667	Aldo Keto reductase
DCS86_RS07625	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DCS86_RS07630	COG3321	synthase
DCS86_RS07630	COG1028	Short-chain dehydrogenase reductase Sdr
DCS86_RS07630	COG0604	alcohol dehydrogenase
DCS86_RS07655	COG0561	phosphatase activity
DCS86_RS07660	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DCS86_RS07665	COG1597	lipid kinase activity
DCS86_RS07665	COG1803	Methylglyoxal synthase
DCS86_RS07670	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DCS86_RS07685	COG0463	Glycosyl transferase, family 2
DCS86_RS07700	COG4085	toxin activity
DCS86_RS07700	COG1525	nuclease
DCS86_RS07700	COG0737	Belongs to the 5'-nucleotidase family
DCS86_RS07710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DCS86_RS07715	COG0166	Belongs to the GPI family
DCS86_RS07725	COG2233	PERMEase
DCS86_RS07750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DCS86_RS07755	COG1396	sequence-specific DNA binding
DCS86_RS07800	COG0395	ABC-type sugar transport system, permease component
DCS86_RS07805	COG1175	transmembrane transport
DCS86_RS07810	COG1653	transport
DCS86_RS07835	COG3386	PFAM SMP-30 Gluconolaconase
DCS86_RS07845	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DCS86_RS07860	COG3842	ATPase activity
DCS86_RS07870	COG0725	ABC transporter, periplasmic molybdate-binding protein
DCS86_RS07900	COG0315	cyclic pyranopterin monophosphate synthase activity
DCS86_RS07905	COG0366	Alpha amylase catalytic
DCS86_RS07930	COG1643	Atp-dependent helicase
DCS86_RS07935	COG3142	Participates in the control of copper homeostasis
DCS86_RS07945	COG0656	L-ascorbic acid biosynthetic process
DCS86_RS07950	COG0315	cyclic pyranopterin monophosphate synthase activity
DCS86_RS07950	COG0521	Mo-molybdopterin cofactor biosynthetic process
DCS86_RS07960	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DCS86_RS07975	COG0789	Transcriptional regulator
DCS86_RS08005	COG3001	Fructosamine kinase
DCS86_RS08030	COG0656	L-ascorbic acid biosynthetic process
DCS86_RS08050	COG0656	L-ascorbic acid biosynthetic process
DCS86_RS08055	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DCS86_RS08065	COG1131	(ABC) transporter
DCS86_RS08100	COG2154	pterin-4-alpha-carbinolamine dehydratase
DCS86_RS08175	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DCS86_RS08265	COG2337	Toxic component of a toxin-antitoxin (TA) module
DCS86_RS08275	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DCS86_RS08310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DCS86_RS08355	COG0297	glycogen (starch) synthase activity
DCS86_RS08365	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
DCS86_RS08370	COG0519	Catalyzes the synthesis of GMP from XMP
DCS86_RS08380	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DCS86_RS08385	COG0726	polysaccharide deacetylase
DCS86_RS08405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DCS86_RS08420	COG0395	ABC-type sugar transport system, permease component
DCS86_RS08430	COG1609	Transcriptional regulator
DCS86_RS08440	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DCS86_RS08450	COG1780	Probably involved in ribonucleotide reductase function
DCS86_RS08470	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DCS86_RS08475	COG2813	Specifically methylates the guanine in position
DCS86_RS08485	COG0246	Mannitol dehydrogenase
DCS86_RS08495	COG1305	Transglutaminase-like
DCS86_RS08505	COG0714	Associated with various cellular activities
DCS86_RS08535	COG3409	Peptidoglycan-binding domain 1 protein
DCS86_RS08540	COG3409	Peptidoglycan-binding domain 1 protein
DCS86_RS08600	COG1716	ATPase activity
DCS86_RS08620	COG0768	penicillin binding
DCS86_RS08625	COG0515	serine threonine protein kinase
DCS86_RS08630	COG0515	serine threonine protein kinase
DCS86_RS08640	COG3764	Sortase (surface protein transpeptidase)
DCS86_RS08730	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DCS86_RS08735	COG0187	DNA topoisomerase II activity
DCS86_RS08740	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
DCS86_RS08745	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DCS86_RS08750	COG0592	DNA-directed DNA polymerase activity
DCS86_RS08755	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DCS86_RS08760	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DCS86_RS08765	COG0594	ribonuclease P activity
DCS86_RS08770	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DCS86_RS08775	COG0706	membrane insertase activity
DCS86_RS08785	COG0357	Ribosomal RNA small subunit methyltransferase G
DCS86_RS08790	COG0659	secondary active sulfate transmembrane transporter activity
DCS86_RS08805	COG4941	Belongs to the sigma-70 factor family
DCS86_RS08810	COG1192	Involved in chromosome partitioning
DCS86_RS08815	COG1475	DNA binding
DCS86_RS08820	COG1181	Belongs to the D-alanine--D-alanine ligase family
DCS86_RS08825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DCS86_RS08830	COG3118	belongs to the thioredoxin family
DCS86_RS08835	COG0492	ferredoxin-NADP+ reductase activity
DCS86_RS08855	COG0617	tRNA 3'-terminal CCA addition
DCS86_RS08865	COG4552	Acetyltransferase involved in intracellular survival and related
DCS86_RS08880	COG0395	ABC-type sugar transport system, permease component
DCS86_RS08885	COG1260	myo-inositol-1-phosphate synthase
DCS86_RS08895	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DCS86_RS08900	COG0360	Binds together with S18 to 16S ribosomal RNA
DCS86_RS08910	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DCS86_RS08915	COG0359	binds to the 23S rRNA
DCS86_RS08925	COG4591	ABC-type transport system involved in lipoprotein release permease component
DCS86_RS08930	COG1136	(ABC) transporter
DCS86_RS08930	COG0577	efflux transmembrane transporter activity
DCS86_RS08935	COG0534	Mate efflux family protein
DCS86_RS08960	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DCS86_RS08970	COG2070	2-Nitropropane dioxygenase
DCS86_RS09020	COG0346	lactoylglutathione lyase activity
DCS86_RS09030	COG0662	Cupin 2, conserved barrel domain protein
DCS86_RS09045	COG1793	dna ligase
DCS86_RS09065	COG1088	dTDP-glucose 4,6-dehydratase activity
DCS86_RS09070	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DCS86_RS09080	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DCS86_RS09090	COG0366	Alpha amylase catalytic
DCS86_RS09105	COG1362	aminopeptidase activity
DCS86_RS09220	COG0667	Aldo Keto reductase
DCS86_RS09250	COG1028	Short-chain dehydrogenase reductase Sdr
DCS86_RS09255	COG1053	succinate dehydrogenase
DCS86_RS09265	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DCS86_RS09300	COG1254	Belongs to the acylphosphatase family
DCS86_RS09325	COG2318	DinB family
DCS86_RS09330	COG1760	l-serine dehydratase
DCS86_RS09345	COG3265	gluconokinase activity
DCS86_RS09360	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DCS86_RS09365	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DCS86_RS09370	COG0477	Major facilitator Superfamily
DCS86_RS09375	COG1609	Transcriptional regulator
DCS86_RS09380	COG0583	DNA-binding transcription factor activity
DCS86_RS09400	COG0577	efflux transmembrane transporter activity
DCS86_RS09400	COG1136	(ABC) transporter
DCS86_RS09405	COG1136	(ABC) transporter
DCS86_RS09450	COG1131	(ABC) transporter
DCS86_RS09510	COG1487	ribonuclease activity
DCS86_RS09515	COG0824	Thioesterase
DCS86_RS09545	COG1501	Belongs to the glycosyl hydrolase 31 family
DCS86_RS09560	COG1132	(ABC) transporter
DCS86_RS09565	COG0667	Aldo Keto reductase
DCS86_RS09595	COG1937	Protein conserved in bacteria
DCS86_RS09615	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DCS86_RS09630	COG1950	PFAM Membrane protein of
DCS86_RS09635	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DCS86_RS09645	COG0022	dehydrogenase e1 component
DCS86_RS09650	COG0508	dehydrogenase complex catalyzes the overall conversion of
DCS86_RS09685	COG0714	Associated with various cellular activities
DCS86_RS09700	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DCS86_RS09735	COG2212	antiporter activity
DCS86_RS09745	COG0651	ATP synthesis coupled electron transport
DCS86_RS09755	COG2111	Na H antiporter
DCS86_RS09755	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DCS86_RS09780	COG0717	Belongs to the dCTP deaminase family
DCS86_RS09800	COG1476	TRANSCRIPTIONal
DCS86_RS09805	COG0435	Glutathione S-transferase
DCS86_RS09830	COG1175	transmembrane transport
DCS86_RS09835	COG0395	ABC-type sugar transport system, permease component
DCS86_RS09865	COG3408	Glycogen debranching enzyme
DCS86_RS09910	COG1082	Xylose isomerase domain protein TIM barrel
DCS86_RS09915	COG0673	inositol 2-dehydrogenase activity
DCS86_RS09925	COG3962	Belongs to the TPP enzyme family
DCS86_RS09930	COG3718	enzyme involved in inositol metabolism
DCS86_RS09945	COG2188	Transcriptional regulator
DCS86_RS09950	COG0628	permease
DCS86_RS09970	COG2045	Belongs to the ComB family
DCS86_RS10015	COG1316	TRANSCRIPTIONal
DCS86_RS10025	COG0494	nUDIX hydrolase
DCS86_RS10040	COG4143	(ABC) transporter
DCS86_RS10045	COG4149	molybdate abc transporter
DCS86_RS10050	COG3842	ATPase activity
DCS86_RS10060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DCS86_RS10075	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
DCS86_RS10085	COG1823	symporter activity
DCS86_RS10115	COG1595	DNA-templated transcription, initiation
DCS86_RS10125	COG0531	amino acid
DCS86_RS10160	COG2326	polyphosphate kinase activity
DCS86_RS10195	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DCS86_RS10215	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DCS86_RS10250	COG5002	protein histidine kinase activity
DCS86_RS10280	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DCS86_RS10300	COG1857	crispr-associated protein
DCS86_RS10315	COG1518	maintenance of DNA repeat elements
DCS86_RS10320	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DCS86_RS10360	COG1397	ADP-ribosylglycohydrolase
DCS86_RS10365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DCS86_RS10370	COG2364	Membrane
DCS86_RS10395	COG3273	potassium ion transport
DCS86_RS10395	COG0471	metal ion transport
DCS86_RS10405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DCS86_RS10440	COG1929	Belongs to the glycerate kinase type-1 family
DCS86_RS10465	COG0110	maltose O-acetyltransferase activity
DCS86_RS10515	COG2066	Belongs to the glutaminase family
DCS86_RS10520	COG4941	Belongs to the sigma-70 factor family
DCS86_RS10550	COG0842	Transport permease protein
DCS86_RS10555	COG1131	(ABC) transporter
DCS86_RS10560	COG1129	ABC transporter
DCS86_RS10560	COG0842	Transport permease protein
DCS86_RS10610	COG1278	Cold shock
DCS86_RS10620	COG0656	L-ascorbic acid biosynthetic process
DCS86_RS10630	COG0443	Heat shock 70 kDa protein
DCS86_RS10640	COG0484	heat shock protein binding
DCS86_RS10645	COG0789	Transcriptional regulator
DCS86_RS10665	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DCS86_RS10670	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
DCS86_RS10680	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DCS86_RS10680	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DCS86_RS10685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DCS86_RS10690	COG0800	Aldolase
DCS86_RS10725	COG2186	Transcriptional regulator
DCS86_RS10730	COG4948	Mandelate Racemase Muconate Lactonizing
DCS86_RS10755	COG3304	Inner membrane component domain
DCS86_RS10765	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DCS86_RS10770	COG0534	Mate efflux family protein
DCS86_RS10775	COG0590	tRNA wobble adenosine to inosine editing
DCS86_RS10865	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DCS86_RS10880	COG1131	(ABC) transporter
DCS86_RS10895	COG0805	protein transport
DCS86_RS10930	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DCS86_RS10935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DCS86_RS10945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DCS86_RS10950	COG0601	transmembrane transport
DCS86_RS10955	COG0747	negative chemotaxis
DCS86_RS10960	COG0277	FAD linked oxidase domain protein
DCS86_RS10975	COG2814	Major facilitator Superfamily
DCS86_RS10990	COG2116	formate transmembrane transporter activity
DCS86_RS11000	COG1803	Methylglyoxal synthase
DCS86_RS11005	COG1408	metallophosphoesterase
DCS86_RS11010	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DCS86_RS11035	COG0596	Alpha beta hydrolase
DCS86_RS11045	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DCS86_RS11090	COG1205	dead DEAH box helicase
DCS86_RS11090	COG1111	helicase
DCS86_RS11100	COG0018	arginyl-trna synthetase
DCS86_RS11115	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DCS86_RS11145	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DCS86_RS11175	COG1454	alcohol dehydrogenase
DCS86_RS11180	COG2890	protein-(glutamine-N5) methyltransferase activity
DCS86_RS11190	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DCS86_RS11190	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DCS86_RS11195	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DCS86_RS11200	COG4592	Periplasmic binding protein
DCS86_RS11205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DCS86_RS11210	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DCS86_RS11215	COG1120	ATPase activity
DCS86_RS11235	COG3654	unkown
DCS86_RS11260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DCS86_RS11260	COG1754	DNA topoisomerase type I activity
DCS86_RS11265	COG0659	secondary active sulfate transmembrane transporter activity
DCS86_RS11280	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DCS86_RS11330	COG0247	lactate metabolic process
DCS86_RS11330	COG0277	FAD linked oxidase domain protein
DCS86_RS11365	COG0791	NLP P60 protein
DCS86_RS11365	COG3103	Sh3 type 3 domain protein
DCS86_RS11365	COG1388	LysM domain
DCS86_RS11375	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DCS86_RS11385	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DCS86_RS11390	COG2027	D-alanyl-D-alanine carboxypeptidase
DCS86_RS11400	COG0037	tRNA processing
DCS86_RS11405	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DCS86_RS11415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DCS86_RS11440	COG0745	RESPONSE REGULATOR receiver
DCS86_RS11455	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DCS86_RS11465	COG0588	phosphoglycerate mutase activity
DCS86_RS11475	COG5002	protein histidine kinase activity
DCS86_RS11495	COG0215	cysteine-tRNA ligase activity
DCS86_RS11500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DCS86_RS11505	COG3459	Glycosyltransferase 36 associated
DCS86_RS11515	COG3842	ATPase activity
DCS86_RS11520	COG3842	ATPase activity
DCS86_RS11525	COG1877	trehalose-phosphatase activity
DCS86_RS11525	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DCS86_RS11550	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DCS86_RS11565	COG0123	including yeast histone deacetylase and acetoin utilization protein
DCS86_RS11575	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DCS86_RS11585	COG2353	YceI-like domain
DCS86_RS11595	COG0406	alpha-ribazole phosphatase activity
DCS86_RS11605	COG0785	Cytochrome C biogenesis protein
DCS86_RS11655	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DCS86_RS11660	COG1253	flavin adenine dinucleotide binding
DCS86_RS11665	COG4948	Mandelate Racemase Muconate Lactonizing
DCS86_RS11670	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DCS86_RS11675	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DCS86_RS11680	COG1169	isochorismate synthase
DCS86_RS11685	COG2226	methyltransferase
DCS86_RS11705	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DCS86_RS11710	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DCS86_RS11715	COG0649	NAD binding
DCS86_RS11730	COG1034	ATP synthesis coupled electron transport
DCS86_RS11735	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DCS86_RS11745	COG0839	Belongs to the complex I subunit 6 family
DCS86_RS11750	COG0713	ATP synthesis coupled electron transport
DCS86_RS11755	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DCS86_RS11765	COG1007	ATP synthesis coupled electron transport
DCS86_RS11770	COG0142	geranyltranstransferase activity
DCS86_RS11775	COG2890	protein-(glutamine-N5) methyltransferase activity
DCS86_RS11780	COG0366	Alpha amylase catalytic
DCS86_RS11790	COG0501	Belongs to the peptidase M48B family
DCS86_RS11810	COG1136	(ABC) transporter
DCS86_RS11815	COG0577	efflux transmembrane transporter activity
DCS86_RS11815	COG1136	(ABC) transporter
DCS86_RS11830	COG0531	amino acid
DCS86_RS11835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DCS86_RS11850	COG1401	restriction endodeoxyribonuclease activity
DCS86_RS11855	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DCS86_RS11860	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DCS86_RS11865	COG1111	helicase
DCS86_RS11865	COG1205	dead DEAH box helicase
DCS86_RS11905	COG1666	GTP binding
DCS86_RS11930	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DCS86_RS11935	COG2030	dehydratase
DCS86_RS11945	COG1609	Transcriptional regulator
DCS86_RS11950	COG0738	Major facilitator superfamily
DCS86_RS11955	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DCS86_RS11965	COG2814	Major facilitator Superfamily
DCS86_RS11970	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DCS86_RS11975	COG0436	Aminotransferase
DCS86_RS11995	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DCS86_RS12000	COG0081	regulation of translation
DCS86_RS12005	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DCS86_RS12010	COG0222	ribosome binding
DCS86_RS12015	COG0085	RNA polymerase activity
DCS86_RS12020	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DCS86_RS12025	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DCS86_RS12030	COG0049	tRNA binding
DCS86_RS12035	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DCS86_RS12040	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DCS86_RS12045	COG0051	transcription antitermination factor activity, RNA binding
DCS86_RS12050	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DCS86_RS12055	COG0088	Forms part of the polypeptide exit tunnel
DCS86_RS12060	COG0089	rRNA binding
DCS86_RS12065	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DCS86_RS12070	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DCS86_RS12075	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DCS86_RS12080	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DCS86_RS12085	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DCS86_RS12090	COG0255	Belongs to the universal ribosomal protein uL29 family
DCS86_RS12095	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DCS86_RS12100	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DCS86_RS12105	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DCS86_RS12110	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DCS86_RS12115	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DCS86_RS12120	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DCS86_RS12125	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DCS86_RS12130	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DCS86_RS12135	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DCS86_RS12140	COG1841	ribosomal large subunit assembly
DCS86_RS12155	COG0563	adenylate kinase activity
DCS86_RS12160	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DCS86_RS12165	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DCS86_RS12170	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DCS86_RS12175	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DCS86_RS12180	COG0202	RNA polymerase activity
DCS86_RS12185	COG0203	ribosomal protein L17
DCS86_RS12190	COG2267	carboxylic ester hydrolase activity
DCS86_RS12205	COG0101	tRNA pseudouridine synthase activity
DCS86_RS12215	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DCS86_RS12220	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DCS86_RS12225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DCS86_RS12235	COG1072	(Pantothenic acid kinase))
DCS86_RS12240	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DCS86_RS12245	COG0736	holo-[acyl-carrier-protein] synthase activity
DCS86_RS12255	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DCS86_RS12260	COG0802	atpase or kinase
DCS86_RS12275	COG0778	Nitroreductase
DCS86_RS12280	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DCS86_RS12290	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DCS86_RS12300	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DCS86_RS12315	COG3493	citrate carrier protein
DCS86_RS12320	COG4565	transcriptional regulatory protein
DCS86_RS12325	COG3290	protein histidine kinase activity
DCS86_RS12330	COG0471	metal ion transport
DCS86_RS12335	COG0114	fumarate hydratase activity
DCS86_RS12340	COG1053	succinate dehydrogenase
DCS86_RS12345	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DCS86_RS12355	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
DCS86_RS12370	COG0516	GMP reductase activity
DCS86_RS12375	COG1105	Belongs to the carbohydrate kinase PfkB family
DCS86_RS12395	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DCS86_RS12405	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
DCS86_RS12415	COG1132	(ABC) transporter
DCS86_RS12435	COG0519	Catalyzes the synthesis of GMP from XMP
DCS86_RS12435	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DCS86_RS12440	COG0438	transferase activity, transferring glycosyl groups
DCS86_RS12475	COG2197	response regulator
DCS86_RS12500	COG4152	abc transporter atp-binding protein
DCS86_RS12525	COG4585	Histidine kinase
DCS86_RS12525	COG2203	Gaf domain
DCS86_RS12570	COG2261	transglycosylase associated protein
DCS86_RS12580	COG0045	succinate-CoA ligase (ADP-forming) activity
DCS86_RS12615	COG2838	Isocitrate dehydrogenase
DCS86_RS12620	COG0039	L-malate dehydrogenase activity
DCS86_RS12635	COG4214	carbohydrate transport
DCS86_RS12645	COG1129	ABC transporter
DCS86_RS12660	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DCS86_RS12665	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DCS86_RS12675	COG0708	Exodeoxyribonuclease III
DCS86_RS12680	COG2318	DinB family
DCS86_RS12685	COG0577	efflux transmembrane transporter activity
DCS86_RS12690	COG0577	efflux transmembrane transporter activity
DCS86_RS12690	COG1136	(ABC) transporter
DCS86_RS12705	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DCS86_RS12710	COG1349	DNA-binding transcription factor activity
DCS86_RS12715	COG0180	Tryptophanyl-tRNA synthetase
DCS86_RS12730	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DCS86_RS12735	COG1053	succinate dehydrogenase
DCS86_RS12745	COG2009	succinate dehydrogenase
DCS86_RS12755	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DCS86_RS12755	COG1473	amidohydrolase
DCS86_RS12760	COG1744	ABC transporter substrate-binding protein PnrA-like
DCS86_RS12765	COG3845	ABC transporter
DCS86_RS12770	COG4603	Belongs to the binding-protein-dependent transport system permease family
DCS86_RS12775	COG1079	Belongs to the binding-protein-dependent transport system permease family
DCS86_RS12800	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DCS86_RS12805	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DCS86_RS12820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DCS86_RS12825	COG1611	Belongs to the LOG family
DCS86_RS12850	COG1595	DNA-templated transcription, initiation
DCS86_RS12860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DCS86_RS12865	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DCS86_RS12895	COG2197	response regulator
DCS86_RS12940	COG0006	proline dipeptidase activity
DCS86_RS12950	COG2095	MarC family integral membrane protein
DCS86_RS12955	COG3401	FG-GAP repeat protein
DCS86_RS12960	COG0009	L-threonylcarbamoyladenylate synthase
DCS86_RS12965	COG0513	Belongs to the DEAD box helicase family
DCS86_RS12985	COG0210	DNA helicase
DCS86_RS13015	COG1904	glucuronate isomerase
DCS86_RS13030	COG0395	ABC-type sugar transport system, permease component
DCS86_RS13035	COG1175	transmembrane transport
DCS86_RS13040	COG0673	inositol 2-dehydrogenase activity
DCS86_RS13045	COG1609	Transcriptional regulator
DCS86_RS13050	COG2721	sulfolactate sulfo-lyase activity
DCS86_RS13070	COG3480	Lon protease (S16) C-terminal proteolytic domain
DCS86_RS13080	COG1615	UPF0182 protein
DCS86_RS13090	COG0179	Fumarylacetoacetate (FAA) hydrolase
DCS86_RS13095	COG1454	alcohol dehydrogenase
DCS86_RS13100	COG0438	transferase activity, transferring glycosyl groups
DCS86_RS13105	COG0438	transferase activity, transferring glycosyl groups
DCS86_RS13125	COG2409	Drug exporters of the RND superfamily
DCS86_RS13130	COG0628	permease
DCS86_RS13135	COG0277	FAD linked oxidase domain protein
DCS86_RS13155	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DCS86_RS13170	COG0714	Associated with various cellular activities
DCS86_RS13190	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DCS86_RS13210	COG1012	belongs to the aldehyde dehydrogenase family
DCS86_RS13215	COG0584	glycerophosphoryl diester phosphodiesterase
DCS86_RS13240	COG2197	response regulator
DCS86_RS13245	COG4585	Histidine kinase
DCS86_RS13250	COG2135	peptidase activity
DCS86_RS13265	COG4721	ABC-type cobalt transport system, permease component
DCS86_RS13270	COG3845	ABC transporter
DCS86_RS13280	COG2409	Drug exporters of the RND superfamily
DCS86_RS13390	COG2354	Protein conserved in bacteria
DCS86_RS13420	COG0358	DNA primase activity
DCS86_RS13470	COG1136	(ABC) transporter
DCS86_RS13515	COG0765	amino acid transport
DCS86_RS13520	COG0765	amino acid transport
DCS86_RS13525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DCS86_RS13540	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DCS86_RS13545	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DCS86_RS13555	COG1104	cysteine desulfurase activity
DCS86_RS13565	COG0179	Fumarylacetoacetate (FAA) hydrolase
DCS86_RS13570	COG1028	Short-chain dehydrogenase reductase Sdr
DCS86_RS13575	COG0667	Aldo Keto reductase
DCS86_RS13585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DCS86_RS13590	COG0405	Gamma-glutamyltransferase
DCS86_RS13595	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DCS86_RS13605	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DCS86_RS13610	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DCS86_RS13610	COG0574	Belongs to the PEP-utilizing enzyme family
DCS86_RS13615	COG2884	Cell division ATP-binding protein ftsE
DCS86_RS13635	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DCS86_RS13640	COG1834	amidinotransferase
DCS86_RS13700	COG0395	ABC-type sugar transport system, permease component
DCS86_RS13705	COG1175	transmembrane transport
DCS86_RS13735	COG1914	H( )-stimulated, divalent metal cation uptake system
DCS86_RS13750	COG1028	Short-chain dehydrogenase reductase Sdr
DCS86_RS13770	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DCS86_RS13775	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DCS86_RS13785	COG2076	Multidrug Resistance protein
DCS86_RS13795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DCS86_RS13800	COG1131	(ABC) transporter
DCS86_RS13830	COG0644	oxidoreductase
DCS86_RS13835	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DCS86_RS13845	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DCS86_RS13855	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DCS86_RS13860	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DCS86_RS13865	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DCS86_RS13870	COG1305	Transglutaminase-like
DCS86_RS13875	COG1301	dicarboxylic acid transport
DCS86_RS13885	COG0488	(ABC) transporter
DCS86_RS13900	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DCS86_RS14040	COG2197	response regulator
DCS86_RS14050	COG4585	Histidine kinase
DCS86_RS14055	COG2116	formate transmembrane transporter activity
DCS86_RS14060	COG4608	Belongs to the ABC transporter superfamily
DCS86_RS14070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DCS86_RS14075	COG0601	transmembrane transport
DCS86_RS14105	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DCS86_RS14145	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DCS86_RS14155	COG0443	Heat shock 70 kDa protein
DCS86_RS14170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DCS86_RS14175	COG0668	transmembrane transport
DCS86_RS14185	COG1263	PTS System
DCS86_RS14185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DCS86_RS14185	COG2190	(PTS) system
DCS86_RS14200	COG0400	carboxylic ester hydrolase activity
DCS86_RS14210	COG2514	catechol 2,3-dioxygenase activity
DCS86_RS14220	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DCS86_RS14230	COG4552	Acetyltransferase involved in intracellular survival and related
DCS86_RS14235	COG3590	peptidase
DCS86_RS14245	COG0698	ribose 5-phosphate isomerase
DCS86_RS14280	COG1832	CoA-binding protein
DCS86_RS14290	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DCS86_RS14295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DCS86_RS14305	COG1116	anion transmembrane transporter activity
DCS86_RS14315	COG1045	serine acetyltransferase
DCS86_RS14345	COG0544	peptidyl-prolyl cis-trans isomerase activity
DCS86_RS14355	COG0740	serine-type endopeptidase activity
DCS86_RS14360	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DCS86_RS14365	COG1605	Chorismate mutase
DCS86_RS14365	COG0287	Prephenate dehydrogenase
DCS86_RS14375	COG1136	(ABC) transporter
DCS86_RS14410	COG3201	nicotinamide mononucleotide transporter
DCS86_RS14440	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DCS86_RS14440	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DCS86_RS14445	COG4172	Belongs to the ABC transporter superfamily
DCS86_RS14450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DCS86_RS14455	COG0601	transmembrane transport
DCS86_RS14475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DCS86_RS14480	COG0778	Nitroreductase
DCS86_RS14480	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
DCS86_RS14485	COG1120	ATPase activity
DCS86_RS14490	COG4139	cobalamin transport
DCS86_RS14500	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DCS86_RS14510	COG1136	(ABC) transporter
DCS86_RS14520	COG1132	(ABC) transporter
DCS86_RS14525	COG1132	(ABC) transporter
DCS86_RS14540	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DCS86_RS14545	COG0285	dihydrofolate synthase activity
DCS86_RS14555	COG2376	Dihydroxyacetone kinase
DCS86_RS14560	COG1461	Dihydroxyacetone kinase
DCS86_RS14565	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
DCS86_RS14575	COG0105	UTP biosynthetic process
DCS86_RS14580	COG1196	nuclear chromosome segregation
DCS86_RS14605	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DCS86_RS14615	COG0228	four-way junction DNA binding
DCS86_RS14620	COG1837	Belongs to the UPF0109 family
DCS86_RS14625	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DCS86_RS14630	COG0336	Belongs to the RNA methyltransferase TrmD family
DCS86_RS14635	COG0335	large ribosomal subunit rRNA binding
DCS86_RS14640	COG0681	Belongs to the peptidase S26 family
DCS86_RS14645	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DCS86_RS14665	COG0792	nuclease activity
DCS86_RS14695	COG0052	Belongs to the universal ribosomal protein uS2 family
DCS86_RS14700	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DCS86_RS14705	COG0528	UMP kinase activity
DCS86_RS14710	COG0233	cytoplasmic translational termination
DCS86_RS14715	COG0575	Belongs to the CDS family
DCS86_RS14720	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DCS86_RS14730	COG0750	zinc metalloprotease
DCS86_RS14735	COG0456	acetyltransferase
DCS86_RS14740	COG0442	prolyl-tRNA aminoacylation
DCS86_RS14750	COG0779	Required for maturation of 30S ribosomal subunits
DCS86_RS14765	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DCS86_RS14765	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DCS86_RS14770	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DCS86_RS14775	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DCS86_RS14780	COG2267	carboxylic ester hydrolase activity
DCS86_RS14785	COG0196	riboflavin kinase activity
DCS86_RS14790	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DCS86_RS14795	COG1185	polyribonucleotide nucleotidyltransferase activity
DCS86_RS14800	COG0612	Peptidase, M16
DCS86_RS14805	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DCS86_RS14825	COG1876	peptidase activity
DCS86_RS14830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DCS86_RS14840	COG1674	ftsk spoiiie
DCS86_RS14850	COG1058	Belongs to the CinA family
DCS86_RS14850	COG1546	Belongs to the CinA family
DCS86_RS14860	COG1396	sequence-specific DNA binding
DCS86_RS14865	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DCS86_RS14870	COG1201	RNA secondary structure unwinding
DCS86_RS14880	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DCS86_RS14885	COG2137	regulation of response to DNA damage stimulus
DCS86_RS14895	COG0765	amino acid transport
DCS86_RS14900	COG0765	amino acid transport
DCS86_RS14905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DCS86_RS14910	COG1126	abc transporter atp-binding protein
DCS86_RS14915	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DCS86_RS14935	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DCS86_RS14940	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DCS86_RS14950	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DCS86_RS14965	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DCS86_RS14975	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DCS86_RS14985	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DCS86_RS15000	COG1278	Cold shock
DCS86_RS15015	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DCS86_RS15025	COG2001	Belongs to the MraZ family
DCS86_RS15030	COG0275	rRNA processing
DCS86_RS15040	COG0768	penicillin binding
DCS86_RS15045	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DCS86_RS15055	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DCS86_RS15060	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DCS86_RS15065	COG0772	Belongs to the SEDS family
DCS86_RS15070	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DCS86_RS15075	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DCS86_RS15085	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DCS86_RS15095	COG1799	cell septum assembly
DCS86_RS15105	COG3599	regulation of cell shape
DCS86_RS15120	COG0415	Belongs to the DNA photolyase family
DCS86_RS15135	COG1132	(ABC) transporter
DCS86_RS15140	COG0587	DNA-directed DNA polymerase activity
DCS86_RS15155	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DCS86_RS15170	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DCS86_RS15175	COG0131	Imidazoleglycerol-phosphate dehydratase
DCS86_RS15185	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DCS86_RS15190	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DCS86_RS15215	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DCS86_RS15225	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DCS86_RS15230	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DCS86_RS15235	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DCS86_RS15250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DCS86_RS15255	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DCS86_RS15265	COG0300	oxidoreductase activity
DCS86_RS15280	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DCS86_RS15285	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DCS86_RS15290	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DCS86_RS15295	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DCS86_RS15305	COG1438	arginine binding
DCS86_RS15310	COG0165	Argininosuccinate lyase
DCS86_RS15320	COG2094	Belongs to the DNA glycosylase MPG family
DCS86_RS15325	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DCS86_RS15355	COG0647	UMP catabolic process
DCS86_RS15370	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DCS86_RS15375	COG0497	DNA recombination
DCS86_RS15400	COG0297	glycogen (starch) synthase activity
DCS86_RS15405	COG0504	CTP synthase activity
DCS86_RS15410	COG0494	nUDIX hydrolase
DCS86_RS15460	COG0719	Fe-S assembly protein
DCS86_RS15470	COG0396	ATPase activity
DCS86_RS15485	COG2151	metal-sulfur cluster biosynthetic enzyme
DCS86_RS15495	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DCS86_RS15505	COG3022	response to hydroperoxide
DCS86_RS15520	COG3237	CsbD-like
DCS86_RS15540	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DCS86_RS15545	COG0174	glutamine synthetase
DCS86_RS15550	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DCS86_RS15575	COG2267	carboxylic ester hydrolase activity
DCS86_RS15600	COG2197	response regulator
DCS86_RS15605	COG0588	phosphoglycerate mutase activity
DCS86_RS15610	COG1764	response to oxidative stress
DCS86_RS15615	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DCS86_RS15640	COG1454	alcohol dehydrogenase
DCS86_RS15640	COG1012	belongs to the aldehyde dehydrogenase family
DCS86_RS15645	COG0477	Major facilitator Superfamily
DCS86_RS15655	COG1881	PFAM PEBP family protein
DCS86_RS15665	COG2910	NAD(P)H-binding
DCS86_RS15675	COG1028	Short-chain dehydrogenase reductase Sdr
DCS86_RS15690	COG1476	TRANSCRIPTIONal
DCS86_RS15725	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DCS86_RS15740	COG2197	response regulator
DCS86_RS15765	COG0477	Major facilitator Superfamily
DCS86_RS15785	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DCS86_RS15865	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DCS86_RS15885	COG1968	undecaprenyl-diphosphatase activity
DCS86_RS15890	COG0598	Magnesium transport protein CorA
DCS86_RS15895	COG0215	cysteine-tRNA ligase activity
DCS86_RS15910	COG1994	Peptidase M50
DCS86_RS15910	COG0517	IMP dehydrogenase activity
DCS86_RS15920	COG1222	aaa ATPase
DCS86_RS15935	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DCS86_RS15940	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DCS86_RS15945	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DCS86_RS15955	COG0107	imidazoleglycerol-phosphate synthase activity
DCS86_RS15965	COG1132	(ABC) transporter
DCS86_RS15970	COG1132	(ABC) transporter
DCS86_RS16010	COG0134	indole-3-glycerol-phosphate synthase activity
DCS86_RS16015	COG0133	tryptophan synthase activity
DCS86_RS16025	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DCS86_RS16030	COG0069	glutamate synthase activity
DCS86_RS16030	COG0067	glutamate synthase
DCS86_RS16030	COG0070	glutamate synthase
DCS86_RS16040	COG0469	pyruvate kinase activity
DCS86_RS16145	COG1192	Involved in chromosome partitioning
DCS86_RS16190	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DCS86_RS16310	COG0739	heme binding
DCS86_RS16310	COG0741	lytic transglycosylase activity
DCS86_RS16310	COG1196	nuclear chromosome segregation
DCS86_RS16385	COG2076	Multidrug Resistance protein
DCS86_RS16405	COG2184	nucleotidyltransferase activity
DCS86_RS16410	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs