locus-tag	class	description
AAX07_RS00010	COG0592	DNA-directed DNA polymerase activity
AAX07_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AAX07_RS00020	COG0187	DNA topoisomerase II activity
AAX07_RS00025	COG0519	Catalyzes the synthesis of GMP from XMP
AAX07_RS00025	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AAX07_RS00030	COG3977	Valine--pyruvate aminotransferase
AAX07_RS00035	COG0251	oxidation-reduction process
AAX07_RS00055	COG0242	peptide deformylase activity
AAX07_RS00060	COG0131	Imidazoleglycerol-phosphate dehydratase
AAX07_RS00065	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AAX07_RS00070	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AAX07_RS00080	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AAX07_RS00125	COG0488	(ABC) transporter
AAX07_RS00130	COG0484	heat shock protein binding
AAX07_RS00135	COG0429	hydrolase of the alpha beta-hydrolase fold
AAX07_RS00140	COG1408	metallophosphoesterase
AAX07_RS00145	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AAX07_RS00150	COG0484	heat shock protein binding
AAX07_RS00165	COG1187	pseudouridine synthase activity
AAX07_RS00170	COG1739	Uncharacterized protein family UPF0029
AAX07_RS00180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AAX07_RS00185	COG0640	Transcriptional regulator
AAX07_RS00195	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AAX07_RS00200	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AAX07_RS00225	COG0583	DNA-binding transcription factor activity
AAX07_RS00230	COG1448	Aminotransferase
AAX07_RS00235	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AAX07_RS00245	COG0795	lipopolysaccharide-transporting ATPase activity
AAX07_RS00255	COG2183	response to ionizing radiation
AAX07_RS00270	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AAX07_RS00275	COG1053	succinate dehydrogenase
AAX07_RS00375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AAX07_RS00400	COG1216	Glycosyl transferase, family 2
AAX07_RS00405	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AAX07_RS00410	COG0166	Belongs to the GPI family
AAX07_RS00420	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AAX07_RS00430	COG4269	membrane
AAX07_RS00440	COG0544	peptidyl-prolyl cis-trans isomerase activity
AAX07_RS00445	COG0740	serine-type endopeptidase activity
AAX07_RS00450	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AAX07_RS00455	COG1250	3-hydroxyacyl-CoA dehydrogenase
AAX07_RS00455	COG1024	Enoyl-CoA hydratase
AAX07_RS00460	COG0183	Belongs to the thiolase family
AAX07_RS00470	COG4607	ABC-type enterochelin transport system periplasmic component
AAX07_RS00475	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AAX07_RS00480	COG4605	iron ion homeostasis
AAX07_RS00490	COG4604	ABC transporter, ATP-binding protein
AAX07_RS00495	COG4145	pantothenate transmembrane transporter activity
AAX07_RS00500	COG3924	membrane
AAX07_RS00515	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AAX07_RS00520	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AAX07_RS00535	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AAX07_RS00540	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AAX07_RS00545	COG0140	phosphoribosyl-ATP diphosphatase activity
AAX07_RS00545	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AAX07_RS00560	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AAX07_RS00570	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AAX07_RS00575	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AAX07_RS00575	COG0072	phenylalanine-tRNA ligase activity
AAX07_RS00580	COG0776	regulation of translation
AAX07_RS00585	COG0254	rRNA binding
AAX07_RS00595	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AAX07_RS00610	COG1522	sequence-specific DNA binding
AAX07_RS00620	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AAX07_RS00630	COG1116	anion transmembrane transporter activity
AAX07_RS00635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AAX07_RS00640	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AAX07_RS00645	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AAX07_RS00650	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AAX07_RS00715	COG0481	GTPase activity
AAX07_RS00725	COG0571	ribonuclease III activity
AAX07_RS00730	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AAX07_RS00740	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AAX07_RS00750	COG1217	gtp-binding protein TYPA
AAX07_RS00770	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AAX07_RS00775	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AAX07_RS00780	COG0513	Belongs to the DEAD box helicase family
AAX07_RS00790	COG2832	Protein of unknown function (DUF454)
AAX07_RS00805	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AAX07_RS00815	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AAX07_RS00820	COG2226	methyltransferase
AAX07_RS00825	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AAX07_RS00830	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AAX07_RS00835	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AAX07_RS00840	COG0107	imidazoleglycerol-phosphate synthase activity
AAX07_RS00845	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AAX07_RS00850	COG0121	glutamine amidotransferase
AAX07_RS00855	COG4106	trans-aconitate 2-methyltransferase activity
AAX07_RS00875	COG1858	cytochrome C peroxidase
AAX07_RS00885	COG0326	Molecular chaperone. Has ATPase activity
AAX07_RS00915	COG0277	FAD linked oxidase domain protein
AAX07_RS00925	COG1301	dicarboxylic acid transport
AAX07_RS00930	COG5383	Protein conserved in bacteria
AAX07_RS00935	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AAX07_RS00955	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AAX07_RS00960	COG0275	rRNA processing
AAX07_RS00975	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AAX07_RS00980	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AAX07_RS00985	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AAX07_RS00995	COG2814	Major facilitator Superfamily
AAX07_RS01000	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AAX07_RS01005	COG1714	RDD family
AAX07_RS01010	COG0792	nuclease activity
AAX07_RS01025	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AAX07_RS01030	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AAX07_RS01040	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AAX07_RS01045	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AAX07_RS01050	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AAX07_RS01050	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AAX07_RS01055	COG1530	ribonuclease E activity
AAX07_RS01060	COG0564	pseudouridine synthase activity
AAX07_RS01065	COG0248	Ppx GppA phosphatase
AAX07_RS01075	COG0037	tRNA processing
AAX07_RS01080	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AAX07_RS01090	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AAX07_RS01090	COG0352	thiamine-phosphate diphosphorylase activity
AAX07_RS01090	COG0351	phosphomethylpyrimidine kinase
AAX07_RS01120	COG0193	aminoacyl-tRNA hydrolase activity
AAX07_RS01125	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AAX07_RS01130	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AAX07_RS01135	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AAX07_RS01150	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AAX07_RS01165	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AAX07_RS01175	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AAX07_RS01225	COG0629	single-stranded DNA binding
AAX07_RS01300	COG3561	AntA/AntB antirepressor
AAX07_RS01400	COG3646	Phage regulatory protein
AAX07_RS01420	COG3617	BRO family, N-terminal domain
AAX07_RS01440	COG2357	RelA SpoT domain protein
AAX07_RS01445	COG0741	lytic transglycosylase activity
AAX07_RS01445	COG1196	nuclear chromosome segregation
AAX07_RS01445	COG0739	heme binding
AAX07_RS01500	COG0586	Pfam SNARE associated Golgi protein
AAX07_RS01520	COG0024	Methionine aminopeptidase
AAX07_RS01525	COG3453	Protein conserved in bacteria
AAX07_RS01525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AAX07_RS01530	COG0446	pyridine nucleotide-disulphide oxidoreductase
AAX07_RS01530	COG1902	pentaerythritol trinitrate reductase activity
AAX07_RS01545	COG3161	chorismate lyase activity
AAX07_RS01565	COG1227	inorganic diphosphatase activity
AAX07_RS01570	COG1472	Belongs to the glycosyl hydrolase 3 family
AAX07_RS01575	COG0793	Belongs to the peptidase S41A family
AAX07_RS01580	COG2205	protein histidine kinase activity
AAX07_RS01585	COG0745	RESPONSE REGULATOR receiver
AAX07_RS01595	COG3038	cytochrome b561
AAX07_RS01600	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AAX07_RS01640	COG0450	alkyl hydroperoxide reductase
AAX07_RS01645	COG2841	Protein conserved in bacteria
AAX07_RS01650	COG3634	alkyl hydroperoxide reductase activity
AAX07_RS01655	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AAX07_RS01665	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AAX07_RS01665	COG0644	oxidoreductase
AAX07_RS01675	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AAX07_RS01685	COG2951	lytic endotransglycosylase activity
AAX07_RS01705	COG0521	Mo-molybdopterin cofactor biosynthetic process
AAX07_RS01715	COG0315	cyclic pyranopterin monophosphate synthase activity
AAX07_RS01720	COG0314	molybdopterin synthase activity
AAX07_RS01725	COG0725	ABC transporter, periplasmic molybdate-binding protein
AAX07_RS01730	COG4149	molybdate abc transporter
AAX07_RS01735	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AAX07_RS01750	COG2197	response regulator
AAX07_RS01755	COG3850	Histidine kinase
AAX07_RS01770	COG2223	nitrite transmembrane transporter activity
AAX07_RS01780	COG0754	glutathionylspermidine amidase activity
AAX07_RS01800	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AAX07_RS01805	COG1464	Belongs to the NlpA lipoprotein family
AAX07_RS01820	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AAX07_RS01835	COG0606	chelatase, subunit chli
AAX07_RS01840	COG0546	phosphoglycolate phosphatase activity
AAX07_RS01855	COG0142	geranyltranstransferase activity
AAX07_RS01860	COG1194	a g-specific adenine glycosylase
AAX07_RS01880	COG0347	Belongs to the P(II) protein family
AAX07_RS01885	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AAX07_RS01890	COG0772	Belongs to the SEDS family
AAX07_RS01895	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AAX07_RS01900	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AAX07_RS01910	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AAX07_RS01915	COG1121	(ABC) transporter
AAX07_RS01920	COG0735	belongs to the Fur family
AAX07_RS01935	COG0356	it plays a direct role in the translocation of protons across the membrane
AAX07_RS01945	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AAX07_RS01950	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AAX07_RS01955	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AAX07_RS01960	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AAX07_RS01965	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AAX07_RS01970	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AAX07_RS01975	COG0745	RESPONSE REGULATOR receiver
AAX07_RS01980	COG2205	protein histidine kinase activity
AAX07_RS01990	COG0228	four-way junction DNA binding
AAX07_RS01995	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AAX07_RS02000	COG0336	Belongs to the RNA methyltransferase TrmD family
AAX07_RS02005	COG0335	large ribosomal subunit rRNA binding
AAX07_RS02015	COG0322	excinuclease ABC activity
AAX07_RS02055	COG0494	nUDIX hydrolase
AAX07_RS02060	COG1765	OsmC-like protein
AAX07_RS02070	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AAX07_RS02080	COG0730	response to heat
AAX07_RS02085	COG1196	nuclear chromosome segregation
AAX07_RS02090	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AAX07_RS02095	COG4106	trans-aconitate 2-methyltransferase activity
AAX07_RS02100	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AAX07_RS02115	COG2354	Protein conserved in bacteria
AAX07_RS02125	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AAX07_RS02135	COG2822	iron ion transport
AAX07_RS02145	COG0672	)-iron permease
AAX07_RS02160	COG2871	sodium ion transport
AAX07_RS02165	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AAX07_RS02170	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AAX07_RS02175	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AAX07_RS02185	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AAX07_RS02190	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AAX07_RS02200	COG3938	Belongs to the proline racemase family
AAX07_RS02205	COG0579	oxidoreductase
AAX07_RS02210	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AAX07_RS02215	COG1012	belongs to the aldehyde dehydrogenase family
AAX07_RS02220	COG1115	amino acid carrier protein
AAX07_RS02235	COG0557	exoribonuclease II activity
AAX07_RS02265	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AAX07_RS02275	COG1121	(ABC) transporter
AAX07_RS02280	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AAX07_RS02285	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AAX07_RS02330	COG0084	hydrolase, TatD family'
AAX07_RS02335	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AAX07_RS02340	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AAX07_RS02345	COG1509	lysine 2,3-aminomutase activity
AAX07_RS02355	COG1401	restriction endodeoxyribonuclease activity
AAX07_RS02365	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AAX07_RS02390	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AAX07_RS02395	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AAX07_RS02420	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AAX07_RS02425	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AAX07_RS02430	COG2233	PERMEase
AAX07_RS02435	COG1115	amino acid carrier protein
AAX07_RS02480	COG3023	N-Acetylmuramoyl-L-alanine amidase
AAX07_RS02505	COG2828	Protein conserved in bacteria
AAX07_RS02525	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AAX07_RS02555	COG0583	DNA-binding transcription factor activity
AAX07_RS02565	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AAX07_RS02575	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AAX07_RS02625	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AAX07_RS02645	COG1301	dicarboxylic acid transport
AAX07_RS02650	COG0730	response to heat
AAX07_RS02660	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AAX07_RS02670	COG0318	PFAM AMP-dependent synthetase and ligase
AAX07_RS02675	COG0318	PFAM AMP-dependent synthetase and ligase
AAX07_RS02680	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AAX07_RS02690	COG1981	membrane
AAX07_RS02700	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AAX07_RS02730	COG0393	Putative heavy-metal-binding
AAX07_RS02740	COG0525	valine-tRNA ligase activity
AAX07_RS02755	COG0123	including yeast histone deacetylase and acetoin utilization protein
AAX07_RS02765	COG4133	protoheme IX ABC transporter activity
AAX07_RS02770	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AAX07_RS02775	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AAX07_RS02785	COG2363	Small membrane protein
AAX07_RS02800	COG4783	chaperone-mediated protein folding
AAX07_RS02805	COG1610	YqeY-like protein
AAX07_RS02815	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AAX07_RS02835	COG2914	Belongs to the UPF0125 (RnfH) family
AAX07_RS02840	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AAX07_RS02895	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AAX07_RS02900	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AAX07_RS02920	COG0783	Belongs to the Dps family
AAX07_RS02930	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AAX07_RS02935	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AAX07_RS02940	COG1012	belongs to the aldehyde dehydrogenase family
AAX07_RS02945	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AAX07_RS02950	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AAX07_RS02955	COG0442	prolyl-tRNA aminoacylation
AAX07_RS02970	COG4221	oxidoreductase activity
AAX07_RS02995	COG0159	tryptophan synthase activity
AAX07_RS03000	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AAX07_RS03005	COG0285	dihydrofolate synthase activity
AAX07_RS03030	COG4783	chaperone-mediated protein folding
AAX07_RS03040	COG4771	TonB-dependent receptor
AAX07_RS03040	COG1629	transport
AAX07_RS03050	COG0408	coproporphyrinogen oxidase activity
AAX07_RS03060	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AAX07_RS03070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AAX07_RS03075	COG2022	thiamine diphosphate biosynthetic process
AAX07_RS03110	COG0504	CTP synthase activity
AAX07_RS03115	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AAX07_RS03120	COG0148	phosphopyruvate hydratase activity
AAX07_RS03125	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AAX07_RS03130	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AAX07_RS03135	COG0658	competence protein
AAX07_RS03135	COG2333	competence protein COMEC
AAX07_RS03150	COG0138	bifunctional purine biosynthesis protein purh
AAX07_RS03160	COG2264	protein methyltransferase activity
AAX07_RS03165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AAX07_RS03170	COG2217	Heavy metal translocating P-type atpase
AAX07_RS03180	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AAX07_RS03185	COG3139	Protein of unknown function (DUF1315)
AAX07_RS03220	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AAX07_RS03240	COG0471	metal ion transport
AAX07_RS03255	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AAX07_RS03265	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AAX07_RS03275	COG0084	hydrolase, TatD family'
AAX07_RS03280	COG4695	Portal protein
AAX07_RS03510	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AAX07_RS03560	COG4382	Mu-like prophage protein Gp16
AAX07_RS03625	COG4771	TonB-dependent receptor
AAX07_RS03625	COG1629	transport
AAX07_RS03640	COG4771	TonB-dependent receptor
AAX07_RS03640	COG1629	transport
AAX07_RS03685	COG1234	tRNA 3'-trailer cleavage
AAX07_RS03690	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AAX07_RS03695	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AAX07_RS03720	COG1741	Belongs to the pirin family
AAX07_RS03725	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AAX07_RS03725	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AAX07_RS03745	COG1294	oxidase, subunit
AAX07_RS03755	COG4232	protein-disulfide reductase activity
AAX07_RS03760	COG1115	amino acid carrier protein
AAX07_RS03785	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AAX07_RS03790	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AAX07_RS03805	COG0628	permease
AAX07_RS03810	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AAX07_RS03815	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AAX07_RS03820	COG0633	Ferredoxin
AAX07_RS03830	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AAX07_RS03835	COG0316	Belongs to the HesB IscA family
AAX07_RS03840	COG0822	iron-sulfur transferase activity
AAX07_RS03850	COG1959	2 iron, 2 sulfur cluster binding
AAX07_RS03865	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AAX07_RS03870	COG1304	FMN binding
AAX07_RS03880	COG1620	l-lactate permease
AAX07_RS03900	COG3012	SEC-C Motif Domain Protein
AAX07_RS03905	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AAX07_RS03905	COG0301	tRNA thio-modification
AAX07_RS03910	COG0708	Exodeoxyribonuclease III
AAX07_RS03930	COG0105	UTP biosynthetic process
AAX07_RS03935	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AAX07_RS03955	COG0124	histidyl-tRNA synthetase
AAX07_RS03965	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AAX07_RS03970	COG1160	GTP binding
AAX07_RS04000	COG3220	belongs to the UPF0276 family
AAX07_RS04010	COG2259	Doxx family
AAX07_RS04025	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AAX07_RS04030	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AAX07_RS04035	COG0347	Belongs to the P(II) protein family
AAX07_RS04040	COG0004	ammonium transporteR
AAX07_RS04060	COG0697	spore germination
AAX07_RS04070	COG1136	(ABC) transporter
AAX07_RS04070	COG0577	efflux transmembrane transporter activity
AAX07_RS04075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AAX07_RS04080	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AAX07_RS04090	COG0697	spore germination
AAX07_RS04140	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AAX07_RS04145	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AAX07_RS04155	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AAX07_RS04160	COG0527	aspartate kinase activity
AAX07_RS04170	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AAX07_RS04190	COG3720	iron ion transport
AAX07_RS04200	COG4139	cobalamin transport
AAX07_RS04205	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AAX07_RS04215	COG0482	sulfurtransferase activity
AAX07_RS04225	COG1335	isochorismatase
AAX07_RS04230	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AAX07_RS04245	COG0445	tRNA wobble uridine modification
AAX07_RS04260	COG2850	peptidyl-arginine hydroxylation
AAX07_RS04265	COG2890	protein-(glutamine-N5) methyltransferase activity
AAX07_RS04290	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AAX07_RS04310	COG0419	ATPase involved in DNA repair
AAX07_RS04315	COG0420	3'-5' exonuclease activity
AAX07_RS04350	COG2431	L-lysine efflux transmembrane transporter activity
AAX07_RS04355	COG0668	transmembrane transport
AAX07_RS04360	COG0116	Belongs to the methyltransferase superfamily
AAX07_RS04360	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AAX07_RS04365	COG0037	tRNA processing
AAX07_RS04370	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AAX07_RS04385	COG0513	Belongs to the DEAD box helicase family
AAX07_RS04390	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AAX07_RS04400	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AAX07_RS04420	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AAX07_RS04445	COG1522	sequence-specific DNA binding
AAX07_RS04450	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AAX07_RS04505	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AAX07_RS04525	COG0583	DNA-binding transcription factor activity
AAX07_RS04530	COG2211	Major facilitator Superfamily
AAX07_RS04535	COG2890	protein-(glutamine-N5) methyltransferase activity
AAX07_RS04540	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AAX07_RS04555	COG0019	diaminopimelate decarboxylase activity
AAX07_RS04570	COG0802	atpase or kinase
AAX07_RS04575	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AAX07_RS04580	COG1923	regulation of RNA biosynthetic process
AAX07_RS04595	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AAX07_RS04600	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AAX07_RS04600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AAX07_RS04605	COG2350	Protein conserved in bacteria
AAX07_RS04620	COG2056	Na+-H+ antiporter family
AAX07_RS04630	COG0612	Peptidase, M16
AAX07_RS04635	COG0552	protein localization to endoplasmic reticulum
AAX07_RS04640	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AAX07_RS04645	COG0167	dihydroorotate dehydrogenase activity
AAX07_RS04665	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AAX07_RS04675	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AAX07_RS04685	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AAX07_RS04700	COG1560	Kdo2-lipid A biosynthetic process
AAX07_RS04705	COG0488	(ABC) transporter
AAX07_RS04710	COG2900	Belongs to the SlyX family
AAX07_RS04720	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AAX07_RS04745	COG1686	Belongs to the peptidase S11 family
AAX07_RS04750	COG0352	thiamine-phosphate diphosphorylase activity
AAX07_RS04755	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AAX07_RS04770	COG0126	phosphoglycerate kinase activity
AAX07_RS04780	COG0191	fructose-bisphosphate aldolase activity
AAX07_RS04785	COG0632	four-way junction helicase activity
AAX07_RS04790	COG0583	DNA-binding transcription factor activity
AAX07_RS04850	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AAX07_RS04855	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AAX07_RS04865	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AAX07_RS04875	COG1971	Probably functions as a manganese efflux pump
AAX07_RS04880	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AAX07_RS04885	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AAX07_RS04890	COG0268	Binds directly to 16S ribosomal RNA
AAX07_RS04920	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AAX07_RS04935	COG0358	DNA primase activity
AAX07_RS04960	COG0823	Involved in the tonB-independent uptake of proteins
AAX07_RS04970	COG1643	Atp-dependent helicase
AAX07_RS04990	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AAX07_RS05000	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AAX07_RS05125	COG1396	sequence-specific DNA binding
AAX07_RS05175	COG4382	Mu-like prophage protein Gp16
AAX07_RS05295	COG3392	D12 class N6 adenine-specific DNA methyltransferase
AAX07_RS05335	COG1917	Cupin 2, conserved barrel domain protein
AAX07_RS05335	COG1396	sequence-specific DNA binding
AAX07_RS05585	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AAX07_RS05610	COG0439	Biotin carboxylase
AAX07_RS05615	COG0511	ligase activity, forming carbon-carbon bonds
AAX07_RS05640	COG1862	Preprotein translocase
AAX07_RS05645	COG1253	flavin adenine dinucleotide binding
AAX07_RS05655	COG0741	lytic transglycosylase activity
AAX07_RS05655	COG1388	LysM domain
AAX07_RS05655	COG0741	lytic transglycosylase activity
AAX07_RS05655	COG1388	LysM domain
AAX07_RS05660	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AAX07_RS05665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AAX07_RS05675	COG3713	MltA-interacting MipA family protein
AAX07_RS05695	COG0508	dehydrogenase complex catalyzes the overall conversion of
AAX07_RS05720	COG1760	l-serine dehydratase
AAX07_RS05730	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AAX07_RS05740	COG1028	Short-chain dehydrogenase reductase Sdr
AAX07_RS05745	COG2610	gluconate transmembrane transporter activity
AAX07_RS05755	COG2031	fatty acid transporter
AAX07_RS05770	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AAX07_RS05775	COG0708	Exodeoxyribonuclease III
AAX07_RS05780	COG0824	Thioesterase
AAX07_RS05785	COG1136	(ABC) transporter
AAX07_RS05800	COG0616	signal peptide processing
AAX07_RS05805	COG3263	regulation of cellular component size
AAX07_RS05830	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AAX07_RS05835	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AAX07_RS05840	COG0477	Major facilitator Superfamily
AAX07_RS05850	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AAX07_RS05860	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AAX07_RS05870	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AAX07_RS05885	COG1733	regulation of RNA biosynthetic process
AAX07_RS05905	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AAX07_RS05925	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AAX07_RS05930	COG4988	ABC transporter
AAX07_RS05980	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AAX07_RS05990	COG0305	Participates in initiation and elongation during chromosome replication
AAX07_RS05995	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AAX07_RS06000	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AAX07_RS06020	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AAX07_RS06025	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AAX07_RS06030	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AAX07_RS06035	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AAX07_RS06045	COG1570	exodeoxyribonuclease VII activity
AAX07_RS06055	COG0793	Belongs to the peptidase S41A family
AAX07_RS06060	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AAX07_RS06065	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AAX07_RS06070	COG1687	branched-chain amino acid
AAX07_RS06085	COG0556	nucleotide-excision repair
AAX07_RS06095	COG1773	rubredoxin
AAX07_RS06105	COG0179	Fumarylacetoacetate (FAA) hydrolase
AAX07_RS06115	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AAX07_RS06120	COG2326	polyphosphate kinase activity
AAX07_RS06130	COG0633	Ferredoxin
AAX07_RS06135	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AAX07_RS06160	COG2966	Psort location CytoplasmicMembrane, score
AAX07_RS06165	COG3610	response to peptide
AAX07_RS06170	COG1538	Outer membrane efflux protein
AAX07_RS06180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AAX07_RS06220	COG1137	ATPase activity
AAX07_RS06225	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AAX07_RS06235	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AAX07_RS06240	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AAX07_RS06240	COG0517	IMP dehydrogenase activity
AAX07_RS06245	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AAX07_RS06255	COG0742	ribosomal rna small subunit methyltransferase
AAX07_RS06260	COG1968	undecaprenyl-diphosphatase activity
AAX07_RS06265	COG1214	PFAM Peptidase M22, glycoprotease
AAX07_RS06270	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AAX07_RS06280	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AAX07_RS06285	COG0542	response to heat
AAX07_RS06290	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AAX07_RS06300	COG2217	Heavy metal translocating P-type atpase
AAX07_RS06310	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AAX07_RS06325	COG1702	phosphate starvation-inducible protein PhoH
AAX07_RS06330	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AAX07_RS06335	COG0284	orotidine-5'-phosphate decarboxylase activity
AAX07_RS06345	COG0776	regulation of translation
AAX07_RS06360	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AAX07_RS06370	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AAX07_RS06385	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AAX07_RS06395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AAX07_RS06400	COG0668	transmembrane transport
AAX07_RS06405	COG1648	precorrin-2 dehydrogenase activity
AAX07_RS06405	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AAX07_RS06415	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AAX07_RS06425	COG0436	Aminotransferase
AAX07_RS06430	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AAX07_RS06435	COG0386	Belongs to the glutathione peroxidase family
AAX07_RS06450	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AAX07_RS06455	COG0512	Glutamine amidotransferase of anthranilate synthase
AAX07_RS06460	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AAX07_RS06465	COG0134	indole-3-glycerol-phosphate synthase activity
AAX07_RS06470	COG2095	MarC family integral membrane protein
AAX07_RS06475	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AAX07_RS06490	COG2252	PERMEase
AAX07_RS06495	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AAX07_RS06500	COG0438	transferase activity, transferring glycosyl groups
AAX07_RS06530	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AAX07_RS06540	COG0400	carboxylic ester hydrolase activity
AAX07_RS06545	COG2321	neutral zinc metallopeptidase
AAX07_RS06555	COG4172	Belongs to the ABC transporter superfamily
AAX07_RS06560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AAX07_RS06565	COG0601	transmembrane transport
AAX07_RS06575	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AAX07_RS06580	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AAX07_RS06585	COG0598	Magnesium transport protein CorA
AAX07_RS06610	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AAX07_RS06615	COG1607	acyl-coa hydrolase
AAX07_RS06620	COG1663	tetraacyldisaccharide 4'-kinase activity
AAX07_RS06625	COG1132	(ABC) transporter
AAX07_RS06630	COG1475	DNA binding
AAX07_RS06635	COG1192	Involved in chromosome partitioning
AAX07_RS06640	COG0357	Ribosomal RNA small subunit methyltransferase G
AAX07_RS06645	COG1067	ATP-dependent peptidase activity
AAX07_RS06695	COG0582	viral genome integration into host DNA
AAX07_RS06710	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AAX07_RS06710	COG0646	methionine synthase
AAX07_RS06715	COG0531	amino acid
AAX07_RS06750	COG1902	pentaerythritol trinitrate reductase activity
AAX07_RS06765	COG0210	DNA helicase
AAX07_RS06790	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AAX07_RS06795	COG1074	ATP-dependent DNA helicase activity
AAX07_RS06800	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AAX07_RS06815	COG1045	serine acetyltransferase
AAX07_RS06825	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AAX07_RS06830	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AAX07_RS06885	COG1960	acyl-CoA dehydrogenase activity
AAX07_RS06890	COG0585	pseudouridine synthase activity
AAX07_RS06910	COG0717	Belongs to the dCTP deaminase family
AAX07_RS06915	COG0489	protein tyrosine kinase activity
AAX07_RS06925	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AAX07_RS06935	COG0343	queuine tRNA-ribosyltransferase activity
AAX07_RS06940	COG0733	neurotransmitter:sodium symporter activity
AAX07_RS06945	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AAX07_RS06950	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AAX07_RS06955	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AAX07_RS06970	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AAX07_RS06975	COG0575	Belongs to the CDS family
AAX07_RS06980	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AAX07_RS06985	COG0233	cytoplasmic translational termination
AAX07_RS06990	COG0528	UMP kinase activity
AAX07_RS07000	COG0471	metal ion transport
AAX07_RS07020	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AAX07_RS07040	COG0321	lipoyl(octanoyl) transferase activity
AAX07_RS07070	COG1473	amidohydrolase
AAX07_RS07075	COG1012	belongs to the aldehyde dehydrogenase family
AAX07_RS07090	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AAX07_RS07095	COG0390	transport system, permease component
AAX07_RS07100	COG4619	ABC transporter
AAX07_RS07105	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AAX07_RS07110	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AAX07_RS07130	COG0729	surface antigen
AAX07_RS07135	COG2814	Major facilitator Superfamily
AAX07_RS07150	COG0359	binds to the 23S rRNA
AAX07_RS07155	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AAX07_RS07160	COG0360	Binds together with S18 to 16S ribosomal RNA
AAX07_RS07170	COG3100	YcgL domain-containing protein
AAX07_RS07180	COG0509	glycine decarboxylation via glycine cleavage system
AAX07_RS07185	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AAX07_RS07185	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AAX07_RS07200	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AAX07_RS07215	COG0129	dihydroxy-acid dehydratase activity
AAX07_RS07225	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AAX07_RS07235	COG1028	Short-chain dehydrogenase reductase Sdr
AAX07_RS07240	COG0183	Belongs to the thiolase family
AAX07_RS07245	COG3293	Transposase
AAX07_RS07250	COG1966	Carbon starvation protein
AAX07_RS07255	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AAX07_RS07270	COG1720	tRNA m6t6A37 methyltransferase activity
AAX07_RS07285	COG0537	adenosine 5'-monophosphoramidase activity
AAX07_RS07295	COG0563	adenylate kinase activity
AAX07_RS07325	COG0742	ribosomal rna small subunit methyltransferase
AAX07_RS07330	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AAX07_RS07335	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AAX07_RS07340	COG0723	plastoquinol--plastocyanin reductase activity
AAX07_RS07345	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AAX07_RS07350	COG2857	Cytochrome c1
AAX07_RS07360	COG0625	glutathione transferase activity
AAX07_RS07370	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AAX07_RS07370	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AAX07_RS07390	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AAX07_RS07395	COG3178	'Phosphotransferase
AAX07_RS07400	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AAX07_RS07405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AAX07_RS07410	COG0583	DNA-binding transcription factor activity
AAX07_RS07420	COG1196	nuclear chromosome segregation
AAX07_RS07420	COG0739	heme binding
AAX07_RS07420	COG0741	lytic transglycosylase activity
AAX07_RS07425	COG0501	Belongs to the peptidase M48B family
AAX07_RS07430	COG1346	cytolysis
AAX07_RS07445	COG0756	dUTP diphosphatase activity
AAX07_RS07450	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AAX07_RS07460	COG1393	Belongs to the ArsC family
AAX07_RS07465	COG0495	leucyl-tRNA aminoacylation
AAX07_RS07485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AAX07_RS07490	COG1136	(ABC) transporter
AAX07_RS07490	COG0577	efflux transmembrane transporter activity
AAX07_RS07515	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AAX07_RS07520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AAX07_RS07535	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AAX07_RS07550	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AAX07_RS07555	COG0217	transcriptional regulatory protein
AAX07_RS07570	COG5002	protein histidine kinase activity
AAX07_RS07580	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AAX07_RS07585	COG0581	inorganic phosphate transmembrane transporter activity
AAX07_RS07590	COG0573	inorganic phosphate transmembrane transporter activity
AAX07_RS07600	COG0018	arginyl-trna synthetase
AAX07_RS07610	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AAX07_RS07620	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AAX07_RS07625	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AAX07_RS07630	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AAX07_RS07635	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AAX07_RS07650	COG1162	GTPase activity
AAX07_RS07665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AAX07_RS07675	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AAX07_RS07685	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AAX07_RS07695	COG1136	(ABC) transporter
AAX07_RS07710	COG2010	Cytochrome c
AAX07_RS07725	COG3278	Belongs to the heme-copper respiratory oxidase family
AAX07_RS07740	COG5295	Hep Hag repeat protein
AAX07_RS07765	COG3676	manually curated
AAX07_RS07780	COG4942	peptidase
AAX07_RS07785	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AAX07_RS07785	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AAX07_RS07785	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AAX07_RS07790	COG1105	Belongs to the carbohydrate kinase PfkB family
AAX07_RS07805	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AAX07_RS07820	COG0505	Belongs to the CarA family
AAX07_RS07835	COG1335	isochorismatase
AAX07_RS07840	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AAX07_RS07845	COG1007	ATP synthesis coupled electron transport
AAX07_RS07850	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AAX07_RS07860	COG0713	ATP synthesis coupled electron transport
AAX07_RS07865	COG0839	Belongs to the complex I subunit 6 family
AAX07_RS07870	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AAX07_RS07875	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AAX07_RS07885	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AAX07_RS07890	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AAX07_RS07900	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AAX07_RS07925	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AAX07_RS07925	COG0649	NAD binding
AAX07_RS07945	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AAX07_RS07950	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AAX07_RS07955	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AAX07_RS07975	COG0348	domain, Protein
AAX07_RS07995	COG1376	ErfK ybiS ycfS ynhG family protein
AAX07_RS08015	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AAX07_RS08020	COG1666	GTP binding
AAX07_RS08030	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AAX07_RS08030	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AAX07_RS08035	COG0842	Transport permease protein
AAX07_RS08040	COG1131	(ABC) transporter
AAX07_RS08070	COG0215	cysteine-tRNA ligase activity
AAX07_RS08085	COG0741	lytic transglycosylase activity
AAX07_RS08090	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AAX07_RS08100	COG0196	riboflavin kinase activity
AAX07_RS08135	COG2188	Transcriptional regulator
AAX07_RS08170	COG0788	formyltetrahydrofolate deformylase activity
AAX07_RS08180	COG1122	ATPase activity
AAX07_RS08205	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AAX07_RS08210	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AAX07_RS08215	COG1519	Transferase
AAX07_RS08220	COG0308	aminopeptidase N
AAX07_RS08270	COG2255	four-way junction helicase activity
AAX07_RS08285	COG1755	Isoprenylcysteine carboxyl methyltransferase
AAX07_RS08290	COG0281	malic enzyme
AAX07_RS08290	COG0280	phosphate acetyltransferase
AAX07_RS08300	COG1028	Short-chain dehydrogenase reductase Sdr
AAX07_RS08305	COG0531	amino acid
AAX07_RS08315	COG2259	Doxx family
AAX07_RS08325	COG0583	DNA-binding transcription factor activity
AAX07_RS08340	COG0194	GDP metabolic process
AAX07_RS08355	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AAX07_RS08360	COG0747	negative chemotaxis
AAX07_RS08385	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AAX07_RS08390	COG2813	Specifically methylates the guanine in position
AAX07_RS08390	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AAX07_RS08400	COG0076	glutamate decarboxylase activity
AAX07_RS08415	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AAX07_RS08445	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AAX07_RS08455	COG2171	N-acyltransferase activity
AAX07_RS08460	COG0602	queuosine metabolic process
AAX07_RS08465	COG1758	RNA polymerase activity
AAX07_RS08470	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AAX07_RS08485	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AAX07_RS08500	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AAX07_RS08505	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AAX07_RS08510	COG2137	regulation of response to DNA damage stimulus
AAX07_RS08530	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AAX07_RS08540	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AAX07_RS08545	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AAX07_RS08560	COG0189	ligase activity
AAX07_RS08570	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AAX07_RS08575	COG0052	Belongs to the universal ribosomal protein uS2 family
AAX07_RS08610	COG1183	phosphatidylcholine synthase activity
AAX07_RS08615	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AAX07_RS08650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AAX07_RS08655	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AAX07_RS08660	COG2975	iron-sulfur cluster assembly
AAX07_RS08665	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AAX07_RS08670	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AAX07_RS08685	COG0753	catalase activity
AAX07_RS08725	COG3022	response to hydroperoxide
AAX07_RS08730	COG0280	phosphate acetyltransferase
AAX07_RS08730	COG0857	belongs to the CobB CobQ family
AAX07_RS08735	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AAX07_RS08740	COG0019	diaminopimelate decarboxylase activity
AAX07_RS08745	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AAX07_RS08765	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AAX07_RS08780	COG0826	peptidase U32
AAX07_RS08790	COG0277	FAD linked oxidase domain protein
AAX07_RS08795	COG0459	protein refolding
AAX07_RS08800	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AAX07_RS08825	COG1295	ribonuclease BN
AAX07_RS08840	COG0540	Belongs to the ATCase OTCase family
AAX07_RS08845	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AAX07_RS08850	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AAX07_RS08855	COG1408	metallophosphoesterase
AAX07_RS08870	COG1278	Cold shock
AAX07_RS08880	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AAX07_RS08895	COG0440	acetolactate synthase activity
AAX07_RS08900	COG0028	Belongs to the TPP enzyme family
AAX07_RS08910	COG1652	LysM domain
AAX07_RS08930	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AAX07_RS08950	COG3101	peptidyl-lysine hydroxylation
AAX07_RS08965	COG0203	ribosomal protein L17
AAX07_RS08970	COG0202	RNA polymerase activity
AAX07_RS08975	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AAX07_RS08980	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AAX07_RS08990	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AAX07_RS09000	COG0200	Binds to the 23S rRNA
AAX07_RS09005	COG1841	ribosomal large subunit assembly
AAX07_RS09015	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AAX07_RS09020	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AAX07_RS09025	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AAX07_RS09030	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AAX07_RS09035	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AAX07_RS09040	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AAX07_RS09045	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AAX07_RS09050	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AAX07_RS09055	COG0255	Belongs to the universal ribosomal protein uL29 family
AAX07_RS09060	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AAX07_RS09065	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AAX07_RS09070	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AAX07_RS09075	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AAX07_RS09080	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AAX07_RS09085	COG0089	rRNA binding
AAX07_RS09090	COG0088	Forms part of the polypeptide exit tunnel
AAX07_RS09095	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AAX07_RS09100	COG0051	transcription antitermination factor activity, RNA binding
AAX07_RS09105	COG1530	ribonuclease E activity
AAX07_RS09110	COG0424	maF-like protein
AAX07_RS09115	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AAX07_RS09125	COG0154	amidase activity
AAX07_RS09130	COG1247	-acetyltransferase
AAX07_RS09135	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AAX07_RS09155	COG1047	Peptidyl-prolyl cis-trans
AAX07_RS09165	COG1187	pseudouridine synthase activity
AAX07_RS09170	COG2885	chlorophyll binding
AAX07_RS09185	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AAX07_RS09190	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AAX07_RS09200	COG1671	Belongs to the UPF0178 family
AAX07_RS09205	COG0628	permease
AAX07_RS09210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AAX07_RS09220	COG2301	Belongs to the HpcH HpaI aldolase family
AAX07_RS09240	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AAX07_RS09255	COG0629	single-stranded DNA binding
AAX07_RS09270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AAX07_RS09340	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AAX07_RS09370	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AAX07_RS09395	COG0339	signal peptide processing
AAX07_RS09405	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AAX07_RS09415	COG0049	tRNA binding
AAX07_RS09420	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AAX07_RS09445	COG2814	Major facilitator Superfamily
AAX07_RS09450	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AAX07_RS09460	COG2983	Belongs to the UPF0260 family
AAX07_RS09470	COG2195	Cleaves the N-terminal amino acid of tripeptides
AAX07_RS09475	COG0561	phosphatase activity
AAX07_RS09480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AAX07_RS09485	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AAX07_RS09490	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AAX07_RS09495	COG0085	RNA polymerase activity
AAX07_RS09510	COG0081	regulation of translation
AAX07_RS09515	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AAX07_RS09535	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AAX07_RS09615	COG2357	RelA SpoT domain protein
AAX07_RS09625	COG3617	BRO family, N-terminal domain
AAX07_RS09650	COG3646	Phage regulatory protein
AAX07_RS09750	COG3617	BRO family, N-terminal domain
AAX07_RS09780	COG3561	AntA/AntB antirepressor
AAX07_RS09815	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AAX07_RS09940	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AAX07_RS09940	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AAX07_RS09950	COG2226	methyltransferase
AAX07_RS09955	COG0586	Pfam SNARE associated Golgi protein
AAX07_RS09975	COG2831	hemolysin activation secretion protein
AAX07_RS10005	COG3210	domain, Protein
AAX07_RS10010	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AAX07_RS10185	COG4197	protein conserved in bacteria, prophage-related
AAX07_RS10250	COG0582	viral genome integration into host DNA
AAX07_RS10255	COG1858	cytochrome C peroxidase
AAX07_RS10270	COG1674	ftsk spoiiie
AAX07_RS10275	COG0492	ferredoxin-NADP+ reductase activity
AAX07_RS10290	COG2081	HI0933 family
AAX07_RS10295	COG4783	chaperone-mediated protein folding
AAX07_RS10300	COG0271	Belongs to the BolA IbaG family
AAX07_RS10310	COG0659	secondary active sulfate transmembrane transporter activity
AAX07_RS10320	COG0564	pseudouridine synthase activity
AAX07_RS10325	COG3118	belongs to the thioredoxin family
AAX07_RS10345	COG0653	protein targeting
AAX07_RS10350	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AAX07_RS10355	COG2824	Alkylphosphonate utilization operon protein PhnA
AAX07_RS10365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AAX07_RS10380	COG0688	phosphatidylethanolamine metabolic process
AAX07_RS10390	COG1490	D-aminoacyl-tRNA deacylase activity
AAX07_RS10410	COG0751	glycine-tRNA ligase activity
AAX07_RS10420	COG0752	glycyl-tRNA synthetase alpha subunit
AAX07_RS10445	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AAX07_RS10650	COG4974	Belongs to the 'phage' integrase family
AAX07_RS10685	COG2175	clavaminate synthase activity
AAX07_RS10695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AAX07_RS10700	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AAX07_RS10705	COG1051	belongs to the nudix hydrolase family
AAX07_RS10705	COG1056	cytidyltransferase-related domain
AAX07_RS10715	COG0786	glutamate:sodium symporter activity
AAX07_RS10720	COG0047	phosphoribosylformylglycinamidine synthase activity
AAX07_RS10720	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AAX07_RS10725	COG2205	protein histidine kinase activity
AAX07_RS10725	COG5002	protein histidine kinase activity
AAX07_RS10725	COG0784	Response regulator, receiver
AAX07_RS10760	COG1185	polyribonucleotide nucleotidyltransferase activity
AAX07_RS10765	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AAX07_RS10775	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AAX07_RS10780	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AAX07_RS10785	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AAX07_RS10790	COG2251	uridine kinase activity
AAX07_RS10790	COG0195	Participates in both transcription termination and antitermination
AAX07_RS10795	COG0779	Required for maturation of 30S ribosomal subunits
AAX07_RS10815	COG0149	triose-phosphate isomerase activity
AAX07_RS10830	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AAX07_RS10835	COG0237	dephospho-CoA kinase activity
AAX07_RS10850	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AAX07_RS10865	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AAX07_RS10865	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AAX07_RS10870	COG2814	Major facilitator Superfamily
AAX07_RS10900	COG0488	(ABC) transporter
AAX07_RS10930	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AAX07_RS10935	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AAX07_RS10945	COG3323	Protein of unknown function (DUF1653)
AAX07_RS10945	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AAX07_RS10950	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AAX07_RS10960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AAX07_RS10965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AAX07_RS10970	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AAX07_RS10975	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AAX07_RS10990	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AAX07_RS10995	COG1960	acyl-CoA dehydrogenase activity
AAX07_RS11000	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AAX07_RS11010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AAX07_RS11015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AAX07_RS11065	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AAX07_RS11075	COG0446	pyridine nucleotide-disulphide oxidoreductase
AAX07_RS11080	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AAX07_RS11080	COG1116	anion transmembrane transporter activity
AAX07_RS11085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AAX07_RS11090	COG1116	anion transmembrane transporter activity
AAX07_RS11110	COG0339	signal peptide processing
AAX07_RS11120	COG0259	pyridoxamine-phosphate oxidase activity
AAX07_RS11125	COG2937	Belongs to the GPAT DAPAT family
AAX07_RS11130	COG1946	Acyl-CoA thioesterase
AAX07_RS11140	COG0523	cobalamin synthesis protein
AAX07_RS11145	COG1253	flavin adenine dinucleotide binding
AAX07_RS11150	COG1028	Short-chain dehydrogenase reductase Sdr
AAX07_RS11160	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AAX07_RS11180	COG1660	Displays ATPase and GTPase activities
AAX07_RS11185	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AAX07_RS11190	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AAX07_RS11195	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AAX07_RS11200	COG0617	tRNA 3'-terminal CCA addition
AAX07_RS11210	COG1555	photosystem II stabilization
AAX07_RS11215	COG3956	TIGRFAM MazG family protein
AAX07_RS11235	COG0583	DNA-binding transcription factor activity
AAX07_RS11240	COG1960	acyl-CoA dehydrogenase activity
AAX07_RS11245	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AAX07_RS11285	COG1064	alcohol dehydrogenase
AAX07_RS11290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AAX07_RS11295	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AAX07_RS11300	COG0583	DNA-binding transcription factor activity
AAX07_RS11305	COG0475	glutathione-regulated potassium exporter activity
AAX07_RS11305	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AAX07_RS11310	COG3150	esterase
AAX07_RS11345	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AAX07_RS11350	COG2918	glutathione biosynthetic process
AAX07_RS11355	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AAX07_RS11360	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AAX07_RS11370	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AAX07_RS11375	COG0165	Argininosuccinate lyase
AAX07_RS11385	COG0181	hydroxymethylbilane synthase activity
AAX07_RS11400	COG0443	Heat shock 70 kDa protein
AAX07_RS11405	COG0745	RESPONSE REGULATOR receiver
AAX07_RS11415	COG2205	protein histidine kinase activity
AAX07_RS11420	COG4452	Inner membrane protein CreD
AAX07_RS11425	COG2991	Protein conserved in bacteria
AAX07_RS11430	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AAX07_RS11435	COG0497	DNA recombination
AAX07_RS11440	COG1678	Uncharacterized ACR, COG1678
AAX07_RS11445	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AAX07_RS11480	COG2813	Specifically methylates the guanine in position
AAX07_RS11495	COG0318	PFAM AMP-dependent synthetase and ligase
AAX07_RS11500	COG1309	transcriptional regulator
AAX07_RS11505	COG1960	acyl-CoA dehydrogenase activity
AAX07_RS11510	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AAX07_RS11515	COG1024	Enoyl-CoA hydratase
AAX07_RS11520	COG4770	biotin carboxylase activity
AAX07_RS11530	COG0583	DNA-binding transcription factor activity
AAX07_RS11535	COG0477	Major facilitator Superfamily
AAX07_RS11540	COG1942	4-Oxalocrotonate Tautomerase
AAX07_RS11560	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AAX07_RS11580	COG2261	transglycosylase associated protein
AAX07_RS11590	COG0758	DNA mediated transformation
AAX07_RS11600	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AAX07_RS11600	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AAX07_RS11615	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AAX07_RS11615	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AAX07_RS11620	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AAX07_RS11625	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AAX07_RS11630	COG0706	membrane insertase activity
AAX07_RS11635	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AAX07_RS11640	COG0594	ribonuclease P activity
AAX07_RS11645	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AAX07_RS11740	COG1280	lysine exporter protein (LysE YggA)
AAX07_RS11765	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AAX07_RS11770	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AAX07_RS11830	COG2369	cell adhesion
AAX07_RS11880	COG2369	cell adhesion
AAX07_RS11915	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AAX07_RS11920	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AAX07_RS11975	COG1876	peptidase activity
AAX07_RS11995	COG3781	membrane
AAX07_RS12000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AAX07_RS12005	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AAX07_RS12020	COG1215	transferase activity, transferring glycosyl groups
AAX07_RS12130	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AAX07_RS12145	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification