MC49_RS01700 91e31ae85856afacabb4b08149d4753d 294 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 292 33.023 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 MC49_RS01700 91e31ae85856afacabb4b08149d4753d 294 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 3 292 2.1E-102 T 29-03-2018 MC49_RS01700 91e31ae85856afacabb4b08149d4753d 294 SUPERFAMILY SSF53335 49 290 2.79E-45 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS01700 91e31ae85856afacabb4b08149d4753d 294 Gene3D G3DSA:3.40.50.150 101 294 2.0E-36 T 29-03-2018 MC49_RS01700 91e31ae85856afacabb4b08149d4753d 294 PIRSF PIRSF000401 1 294 3.3E-93 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 MC49_RS01700 91e31ae85856afacabb4b08149d4753d 294 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 286 4.2E-115 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 MC49_RS11765 12592b830d05b667a68904a17eea1424 127 PIRSF PIRSF000378 2 127 4.6E-53 T 29-03-2018 IPR011140 Autonomous glycyl radical cofactor GrcA MC49_RS11765 12592b830d05b667a68904a17eea1424 127 SUPERFAMILY SSF51998 65 125 5.49E-24 T 29-03-2018 MC49_RS11765 12592b830d05b667a68904a17eea1424 127 Hamap MF_00806 Autonomous glycyl radical cofactor [grcA]. 1 127 39.441 T 29-03-2018 IPR011140 Autonomous glycyl radical cofactor GrcA MC49_RS11765 12592b830d05b667a68904a17eea1424 127 Pfam PF01228 Glycine radical 60 108 5.4E-21 T 29-03-2018 IPR001150 Glycine radical domain GO:0003824|GO:0008152 MC49_RS11765 12592b830d05b667a68904a17eea1424 127 Gene3D G3DSA:3.20.70.20 45 127 9.2E-30 T 29-03-2018 MC49_RS11765 12592b830d05b667a68904a17eea1424 127 ProSitePatterns PS00850 Glycine radical domain signature. 97 105 - T 29-03-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site MC49_RS11765 12592b830d05b667a68904a17eea1424 127 TIGRFAM TIGR04365 spare_glycyl: autonomous glycyl radical cofactor GrcA 2 127 3.0E-67 T 29-03-2018 IPR011140 Autonomous glycyl radical cofactor GrcA MC49_RS18175 d8074ece6548676cb52b5302254e5106 338 Gene3D G3DSA:3.40.50.720 2 207 9.7E-39 T 29-03-2018 MC49_RS18175 d8074ece6548676cb52b5302254e5106 338 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 324 3.3E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS18175 d8074ece6548676cb52b5302254e5106 338 SUPERFAMILY SSF51735 3 336 1.72E-94 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS18175 d8074ece6548676cb52b5302254e5106 338 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 3 335 1.6E-139 T 29-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 MC49_RS18175 d8074ece6548676cb52b5302254e5106 338 Gene3D G3DSA:3.90.25.10 256 337 8.8E-26 T 29-03-2018 MC49_RS18175 d8074ece6548676cb52b5302254e5106 338 Gene3D G3DSA:3.90.25.10 208 255 9.1E-12 T 29-03-2018 MC49_RS07935 808729ab0bcd5ef0977aa502f786056b 272 Pfam PF00899 ThiF family 17 268 9.8E-40 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MC49_RS07935 808729ab0bcd5ef0977aa502f786056b 272 SUPERFAMILY SSF69572 4 264 2.88E-63 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MC49_RS07935 808729ab0bcd5ef0977aa502f786056b 272 Gene3D G3DSA:3.40.50.720 3 270 1.1E-52 T 29-03-2018 MC49_RS09080 872a0ec84d9b1e51653a78f32a0f108c 261 Gene3D G3DSA:1.10.10.60 85 206 1.6E-9 T 29-03-2018 MC49_RS09080 872a0ec84d9b1e51653a78f32a0f108c 261 SUPERFAMILY SSF51182 21 168 3.26E-11 T 29-03-2018 IPR011051 RmlC-like cupin domain MC49_RS09080 872a0ec84d9b1e51653a78f32a0f108c 261 SUPERFAMILY SSF46689 217 254 1.12E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS09080 872a0ec84d9b1e51653a78f32a0f108c 261 SMART SM00342 170 252 7.8E-18 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MC49_RS09080 872a0ec84d9b1e51653a78f32a0f108c 261 SUPERFAMILY SSF46689 173 205 2.82E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS09080 872a0ec84d9b1e51653a78f32a0f108c 261 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 221 236 2.1E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MC49_RS09080 872a0ec84d9b1e51653a78f32a0f108c 261 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 236 252 2.1E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MC49_RS09080 872a0ec84d9b1e51653a78f32a0f108c 261 Pfam PF12833 Helix-turn-helix domain 176 253 8.2E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MC49_RS09080 872a0ec84d9b1e51653a78f32a0f108c 261 Gene3D G3DSA:2.60.120.10 14 84 5.7E-4 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MC49_RS09080 872a0ec84d9b1e51653a78f32a0f108c 261 Gene3D G3DSA:1.10.10.60 209 254 1.7E-8 T 29-03-2018 MC49_RS12350 43e49e31ec07c170cfb19c339cd5752d 354 Gene3D G3DSA:1.20.1630.10 11 295 8.7E-42 T 29-03-2018 MC49_RS12350 43e49e31ec07c170cfb19c339cd5752d 354 Pfam PF03916 Polysulphide reductase, NrfD 12 291 1.1E-29 T 29-03-2018 IPR005614 NrfD family MC49_RS10365 8813916ef336a6f2722cb9fe07857739 588 Gene3D G3DSA:3.50.50.60 302 430 1.5E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS10365 8813916ef336a6f2722cb9fe07857739 588 Gene3D G3DSA:3.50.50.60 2 294 1.7E-48 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS10365 8813916ef336a6f2722cb9fe07857739 588 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 6 588 2.0E-274 T 29-03-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 MC49_RS10365 8813916ef336a6f2722cb9fe07857739 588 Gene3D G3DSA:4.10.80.40 541 588 3.9E-12 T 29-03-2018 MC49_RS10365 8813916ef336a6f2722cb9fe07857739 588 Pfam PF02910 Fumarate reductase flavoprotein C-term 460 588 1.3E-33 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MC49_RS10365 8813916ef336a6f2722cb9fe07857739 588 SUPERFAMILY SSF51905 359 438 2.11E-75 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS10365 8813916ef336a6f2722cb9fe07857739 588 SUPERFAMILY SSF51905 5 259 2.11E-75 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS10365 8813916ef336a6f2722cb9fe07857739 588 PIRSF PIRSF000171 1 579 2.2E-47 T 29-03-2018 MC49_RS10365 8813916ef336a6f2722cb9fe07857739 588 SUPERFAMILY SSF46977 452 588 4.19E-44 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MC49_RS10365 8813916ef336a6f2722cb9fe07857739 588 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 43 52 - T 29-03-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MC49_RS10365 8813916ef336a6f2722cb9fe07857739 588 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 9 588 3.9E-240 T 29-03-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MC49_RS10365 8813916ef336a6f2722cb9fe07857739 588 Gene3D G3DSA:1.20.58.100 431 540 1.1E-34 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MC49_RS10365 8813916ef336a6f2722cb9fe07857739 588 Pfam PF00890 FAD binding domain 9 405 1.6E-118 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MC49_RS10365 8813916ef336a6f2722cb9fe07857739 588 SUPERFAMILY SSF56425 236 356 2.39E-42 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MC49_RS01650 dd929ddc222ddaca38e67dbed1eb8487 285 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 153 173 - T 29-03-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site MC49_RS01650 dd929ddc222ddaca38e67dbed1eb8487 285 Pfam PF00795 Carbon-nitrogen hydrolase 6 255 6.4E-47 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MC49_RS01650 dd929ddc222ddaca38e67dbed1eb8487 285 Gene3D G3DSA:3.60.110.10 1 271 5.3E-68 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MC49_RS01650 dd929ddc222ddaca38e67dbed1eb8487 285 SUPERFAMILY SSF56317 2 266 1.03E-69 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MC49_RS06265 3551b0fa112f17b5d622686ee070ac8c 406 PIRSF PIRSF000521 173 402 4.3E-36 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MC49_RS06265 3551b0fa112f17b5d622686ee070ac8c 406 PIRSF PIRSF000521 23 155 3.8E-7 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MC49_RS06265 3551b0fa112f17b5d622686ee070ac8c 406 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 16 399 9.3E-149 T 29-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 MC49_RS06265 3551b0fa112f17b5d622686ee070ac8c 406 Gene3D G3DSA:3.90.1150.10 2 171 9.1E-45 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS06265 3551b0fa112f17b5d622686ee070ac8c 406 Gene3D G3DSA:3.90.1150.10 292 406 4.9E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS06265 3551b0fa112f17b5d622686ee070ac8c 406 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 222 259 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MC49_RS06265 3551b0fa112f17b5d622686ee070ac8c 406 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 13 400 45.768 T 29-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 MC49_RS06265 3551b0fa112f17b5d622686ee070ac8c 406 Pfam PF00202 Aminotransferase class-III 25 399 3.4E-130 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MC49_RS06265 3551b0fa112f17b5d622686ee070ac8c 406 TIGRFAM TIGR03246 arg_catab_astC: succinylornithine transaminase family 7 401 2.2E-195 T 29-03-2018 IPR017652 Acetyl/Succinylornithine transaminase family, bacteria GO:0006520|GO:0008483|GO:0030170 MC49_RS06265 3551b0fa112f17b5d622686ee070ac8c 406 Gene3D G3DSA:3.40.640.10 172 291 2.1E-43 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS06265 3551b0fa112f17b5d622686ee070ac8c 406 SUPERFAMILY SSF53383 16 401 2.66E-125 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS03860 f53d3c263338f79f8893baf8fb8b143f 676 SUPERFAMILY SSF52540 1 638 6.73E-166 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS03860 f53d3c263338f79f8893baf8fb8b143f 676 Pfam PF00580 UvrD/REP helicase N-terminal domain 3 266 4.9E-76 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 MC49_RS03860 f53d3c263338f79f8893baf8fb8b143f 676 TIGRFAM TIGR01074 rep: ATP-dependent DNA helicase Rep 2 668 0.0 T 29-03-2018 IPR005752 ATP-dependent DNA helicase Rep GO:0003677|GO:0004003|GO:0005524|GO:0006268 MC49_RS03860 f53d3c263338f79f8893baf8fb8b143f 676 Gene3D G3DSA:1.10.486.10 377 551 2.4E-37 T 29-03-2018 MC49_RS03860 f53d3c263338f79f8893baf8fb8b143f 676 Pfam PF13361 UvrD-like helicase C-terminal domain 271 613 1.7E-72 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MC49_RS03860 f53d3c263338f79f8893baf8fb8b143f 676 Hamap MF_01920 ATP-dependent DNA helicase Rep [rep]. 1 669 40.242 T 29-03-2018 IPR005752 ATP-dependent DNA helicase Rep GO:0003677|GO:0004003|GO:0005524|GO:0006268 MC49_RS03860 f53d3c263338f79f8893baf8fb8b143f 676 Gene3D G3DSA:3.40.50.300 276 376 1.3E-21 T 29-03-2018 MC49_RS03860 f53d3c263338f79f8893baf8fb8b143f 676 Gene3D G3DSA:3.40.50.300 1 132 4.9E-27 T 29-03-2018 MC49_RS03860 f53d3c263338f79f8893baf8fb8b143f 676 Gene3D G3DSA:3.40.50.300 133 275 2.3E-28 T 29-03-2018 MC49_RS18710 75c53374ff8bdb39f34dfd99d17115a5 573 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 392 542 1.4E-46 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MC49_RS18710 75c53374ff8bdb39f34dfd99d17115a5 573 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 429 448 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 MC49_RS18710 75c53374ff8bdb39f34dfd99d17115a5 573 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 194 328 1.4E-43 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MC49_RS18710 75c53374ff8bdb39f34dfd99d17115a5 573 SUPERFAMILY SSF52518 369 566 3.75E-64 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MC49_RS18710 75c53374ff8bdb39f34dfd99d17115a5 573 SUPERFAMILY SSF52518 2 183 1.26E-66 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MC49_RS18710 75c53374ff8bdb39f34dfd99d17115a5 573 Gene3D G3DSA:3.40.50.970 353 560 8.3E-49 T 29-03-2018 MC49_RS18710 75c53374ff8bdb39f34dfd99d17115a5 573 Gene3D G3DSA:3.40.50.1220 197 352 2.6E-50 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MC49_RS18710 75c53374ff8bdb39f34dfd99d17115a5 573 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 4 568 6.0E-266 T 29-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 MC49_RS18710 75c53374ff8bdb39f34dfd99d17115a5 573 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 171 4.2E-59 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MC49_RS18710 75c53374ff8bdb39f34dfd99d17115a5 573 Gene3D G3DSA:3.40.50.970 1 196 6.7E-66 T 29-03-2018 MC49_RS18710 75c53374ff8bdb39f34dfd99d17115a5 573 SUPERFAMILY SSF52467 189 360 6.93E-59 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MC49_RS06300 cfaa6763fa3e8c13579c3ef9ffa6658f 200 Pfam PF01810 LysE type translocator 15 180 4.1E-16 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MC49_RS15845 f061610921654956595db3e79ec659a6 287 Hamap MF_01062 Phosphoenolpyruvate synthase regulatory protein [ppsR]. 16 286 70.435 T 29-03-2018 IPR026530 Phosphoenolpyruvate synthase regulatory protein MC49_RS15845 f061610921654956595db3e79ec659a6 287 Pfam PF03618 Kinase/pyrophosphorylase 19 277 2.8E-72 T 29-03-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 MC49_RS15845 f061610921654956595db3e79ec659a6 287 SUPERFAMILY SSF47454 187 244 8.11E-5 T 29-03-2018 IPR008917 Transcription factor, Skn-1-like, DNA-binding domain GO:0003677|GO:0006355 MC49_RS15845 f061610921654956595db3e79ec659a6 287 Gene3D G3DSA:3.40.50.300 62 285 2.9E-4 T 29-03-2018 MC49_RS00635 00edaf32e90746de2bba2253f1bcdf47 1138 Pfam PF12795 Mechanosensitive ion channel porin domain 52 294 1.1E-58 T 29-03-2018 IPR024393 Mechanosensitive ion channel MscS, porin domain MC49_RS00635 00edaf32e90746de2bba2253f1bcdf47 1138 Pfam PF00924 Mechanosensitive ion channel 907 1106 4.4E-58 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MC49_RS00635 00edaf32e90746de2bba2253f1bcdf47 1138 SUPERFAMILY SSF82689 1017 1117 8.89E-27 T 29-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 MC49_RS00635 00edaf32e90746de2bba2253f1bcdf47 1138 Gene3D G3DSA:3.30.70.100 1017 1111 5.1E-23 T 29-03-2018 MC49_RS00635 00edaf32e90746de2bba2253f1bcdf47 1138 Gene3D G3DSA:2.30.30.60 966 1016 1.4E-12 T 29-03-2018 MC49_RS00635 00edaf32e90746de2bba2253f1bcdf47 1138 SUPERFAMILY SSF50182 950 1015 7.19E-17 T 29-03-2018 IPR010920 LSM domain MC49_RS00635 00edaf32e90746de2bba2253f1bcdf47 1138 Pfam PF12794 Mechanosensitive ion channel inner membrane domain 1 521 846 2.9E-95 T 29-03-2018 IPR025692 Mechanosensitive ion channel inner membrane domain 1 MC49_RS00635 00edaf32e90746de2bba2253f1bcdf47 1138 SUPERFAMILY SSF82861 865 948 2.09E-5 T 29-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 MC49_RS12690 6900761b939b4f072dac1016d281e680 132 Gene3D G3DSA:1.20.120.340 2 129 6.0E-38 T 29-03-2018 MC49_RS12690 6900761b939b4f072dac1016d281e680 132 SUPERFAMILY SSF101116 8 130 9.42E-38 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 MC49_RS12690 6900761b939b4f072dac1016d281e680 132 PIRSF PIRSF039090 1 132 2.0E-41 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 MC49_RS12690 6900761b939b4f072dac1016d281e680 132 Pfam PF02561 Flagellar protein FliS 8 125 6.0E-35 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 MC49_RS12690 6900761b939b4f072dac1016d281e680 132 TIGRFAM TIGR00208 fliS: flagellar protein FliS 1 125 1.7E-35 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 MC49_RS01735 2ab5c739098082eaf6f8fa0240276046 490 Gene3D G3DSA:2.30.40.10 3 75 4.4E-18 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS01735 2ab5c739098082eaf6f8fa0240276046 490 SUPERFAMILY SSF51556 63 372 7.34E-55 T 29-03-2018 IPR032466 Metal-dependent hydrolase MC49_RS01735 2ab5c739098082eaf6f8fa0240276046 490 SUPERFAMILY SSF51338 371 440 2.16E-22 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS01735 2ab5c739098082eaf6f8fa0240276046 490 SUPERFAMILY SSF51338 6 63 2.16E-22 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS01735 2ab5c739098082eaf6f8fa0240276046 490 Gene3D G3DSA:3.20.20.140 76 358 1.8E-41 T 29-03-2018 MC49_RS01735 2ab5c739098082eaf6f8fa0240276046 490 Gene3D G3DSA:2.30.40.10 359 449 1.1E-8 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS01735 2ab5c739098082eaf6f8fa0240276046 490 Pfam PF01979 Amidohydrolase family 60 417 4.3E-25 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MC49_RS10715 5aa0ab761d4242ae1164641725aca1bf 573 Gene3D G3DSA:2.30.40.10 510 573 1.3E-11 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS10715 5aa0ab761d4242ae1164641725aca1bf 573 SUPERFAMILY SSF51338 529 570 1.13E-24 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS10715 5aa0ab761d4242ae1164641725aca1bf 573 SUPERFAMILY SSF51338 5 65 1.13E-24 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS10715 5aa0ab761d4242ae1164641725aca1bf 573 Gene3D G3DSA:3.20.20.140 74 509 9.2E-34 T 29-03-2018 MC49_RS10715 5aa0ab761d4242ae1164641725aca1bf 573 Gene3D G3DSA:2.30.40.10 3 73 1.0E-18 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS10715 5aa0ab761d4242ae1164641725aca1bf 573 Pfam PF07969 Amidohydrolase family 53 570 6.4E-76 T 29-03-2018 IPR013108 Amidohydrolase 3 MC49_RS10715 5aa0ab761d4242ae1164641725aca1bf 573 SUPERFAMILY SSF51556 64 110 1.19E-28 T 29-03-2018 IPR032466 Metal-dependent hydrolase MC49_RS10715 5aa0ab761d4242ae1164641725aca1bf 573 SUPERFAMILY SSF51556 206 270 1.19E-28 T 29-03-2018 IPR032466 Metal-dependent hydrolase MC49_RS10715 5aa0ab761d4242ae1164641725aca1bf 573 SUPERFAMILY SSF51556 300 530 1.19E-28 T 29-03-2018 IPR032466 Metal-dependent hydrolase MC49_RS07900 ebdff12b7277f8d9e4c4beb412f23ad6 610 SUPERFAMILY SSF52540 13 362 3.76E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS07900 ebdff12b7277f8d9e4c4beb412f23ad6 610 SUPERFAMILY SSF52540 436 608 5.84E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS07900 ebdff12b7277f8d9e4c4beb412f23ad6 610 SUPERFAMILY SSF52540 284 380 5.84E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS07900 ebdff12b7277f8d9e4c4beb412f23ad6 610 Hamap MF_01487 RecBCD enzyme subunit RecD [recD]. 14 607 51.141 T 29-03-2018 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 MC49_RS07900 ebdff12b7277f8d9e4c4beb412f23ad6 610 Gene3D G3DSA:3.40.50.300 115 357 4.1E-58 T 29-03-2018 MC49_RS07900 ebdff12b7277f8d9e4c4beb412f23ad6 610 TIGRFAM TIGR01447 recD: exodeoxyribonuclease V, alpha subunit 7 609 1.1E-184 T 29-03-2018 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 MC49_RS07900 ebdff12b7277f8d9e4c4beb412f23ad6 610 Pfam PF13604 AAA domain 157 318 1.5E-30 T 29-03-2018 MC49_RS07900 ebdff12b7277f8d9e4c4beb412f23ad6 610 Gene3D G3DSA:3.40.50.300 367 472 3.0E-13 T 29-03-2018 MC49_RS07900 ebdff12b7277f8d9e4c4beb412f23ad6 610 Gene3D G3DSA:3.40.50.300 473 598 1.1E-22 T 29-03-2018 MC49_RS07900 ebdff12b7277f8d9e4c4beb412f23ad6 610 SMART SM00382 166 328 0.0037 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS07900 ebdff12b7277f8d9e4c4beb412f23ad6 610 Pfam PF13538 UvrD-like helicase C-terminal domain 538 584 1.9E-14 T 29-03-2018 IPR027785 UvrD-like helicase C-terminal domain MC49_RS11280 bb06d086950e4ad690c6fd11ffdfdaa3 549 Gene3D G3DSA:1.20.58.60 440 548 3.3E-4 T 29-03-2018 MC49_RS11280 bb06d086950e4ad690c6fd11ffdfdaa3 549 Pfam PF02470 MlaD protein 289 392 1.1E-14 T 29-03-2018 IPR003399 Mce/MlaD MC49_RS11280 bb06d086950e4ad690c6fd11ffdfdaa3 549 Pfam PF02470 MlaD protein 160 220 1.8E-7 T 29-03-2018 IPR003399 Mce/MlaD MC49_RS11280 bb06d086950e4ad690c6fd11ffdfdaa3 549 Pfam PF02470 MlaD protein 45 135 5.3E-9 T 29-03-2018 IPR003399 Mce/MlaD MC49_RS16305 e27fb39039833a9fcfb25b51fcd0d051 1030 Gene3D G3DSA:3.30.70.1430 557 652 8.2E-12 T 29-03-2018 MC49_RS16305 e27fb39039833a9fcfb25b51fcd0d051 1030 SUPERFAMILY SSF82866 811 1009 6.02E-43 T 29-03-2018 MC49_RS16305 e27fb39039833a9fcfb25b51fcd0d051 1030 SUPERFAMILY SSF82866 290 490 1.83E-46 T 29-03-2018 MC49_RS16305 e27fb39039833a9fcfb25b51fcd0d051 1030 Gene3D G3DSA:3.30.70.1430 40 142 4.2E-26 T 29-03-2018 MC49_RS16305 e27fb39039833a9fcfb25b51fcd0d051 1030 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 4.4E-83 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS16305 e27fb39039833a9fcfb25b51fcd0d051 1030 PRINTS PR00702 Acriflavin resistance protein family signature 542 559 4.4E-83 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS16305 e27fb39039833a9fcfb25b51fcd0d051 1030 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 4.4E-83 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS16305 e27fb39039833a9fcfb25b51fcd0d051 1030 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 4.4E-83 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS16305 e27fb39039833a9fcfb25b51fcd0d051 1030 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 4.4E-83 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS16305 e27fb39039833a9fcfb25b51fcd0d051 1030 PRINTS PR00702 Acriflavin resistance protein family signature 605 619 4.4E-83 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS16305 e27fb39039833a9fcfb25b51fcd0d051 1030 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 4.4E-83 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS16305 e27fb39039833a9fcfb25b51fcd0d051 1030 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 4.4E-83 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS16305 e27fb39039833a9fcfb25b51fcd0d051 1030 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 4.4E-83 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS16305 e27fb39039833a9fcfb25b51fcd0d051 1030 SUPERFAMILY SSF82714 183 266 4.58E-16 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MC49_RS16305 e27fb39039833a9fcfb25b51fcd0d051 1030 Gene3D G3DSA:1.20.1640.10 281 503 8.3E-48 T 29-03-2018 MC49_RS16305 e27fb39039833a9fcfb25b51fcd0d051 1030 Gene3D G3DSA:1.20.1640.10 801 1021 2.5E-36 T 29-03-2018 MC49_RS16305 e27fb39039833a9fcfb25b51fcd0d051 1030 SUPERFAMILY SSF82693 555 650 4.18E-15 T 29-03-2018 MC49_RS16305 e27fb39039833a9fcfb25b51fcd0d051 1030 Hamap MF_01424 Multidrug resistance protein MdtC [mdtC]. 1 1021 25.444 T 29-03-2018 IPR023931 Multidrug resistance protein MdtC MC49_RS16305 e27fb39039833a9fcfb25b51fcd0d051 1030 SUPERFAMILY SSF82693 40 134 1.59E-23 T 29-03-2018 MC49_RS16305 e27fb39039833a9fcfb25b51fcd0d051 1030 Pfam PF00873 AcrB/AcrD/AcrF family 4 1007 0.0 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS16305 e27fb39039833a9fcfb25b51fcd0d051 1030 SUPERFAMILY SSF82714 703 785 1.96E-15 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MC49_RS16305 e27fb39039833a9fcfb25b51fcd0d051 1030 SUPERFAMILY SSF82693 665 701 6.28E-6 T 29-03-2018 MC49_RS16305 e27fb39039833a9fcfb25b51fcd0d051 1030 SUPERFAMILY SSF82693 788 835 6.28E-6 T 29-03-2018 MC49_RS16305 e27fb39039833a9fcfb25b51fcd0d051 1030 SUPERFAMILY SSF82693 136 182 1.54E-21 T 29-03-2018 MC49_RS16305 e27fb39039833a9fcfb25b51fcd0d051 1030 SUPERFAMILY SSF82693 268 324 1.54E-21 T 29-03-2018 MC49_RS16305 e27fb39039833a9fcfb25b51fcd0d051 1030 Gene3D G3DSA:3.30.2090.10 701 788 4.5E-16 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MC49_RS16305 e27fb39039833a9fcfb25b51fcd0d051 1030 Gene3D G3DSA:3.30.2090.10 181 269 2.5E-14 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MC49_RS17985 c1bd7eba774f06e508ec928d9ec32cf5 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 5.9E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS17985 c1bd7eba774f06e508ec928d9ec32cf5 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 5.9E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS17985 c1bd7eba774f06e508ec928d9ec32cf5 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 5.9E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS17985 c1bd7eba774f06e508ec928d9ec32cf5 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 5.9E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS17985 c1bd7eba774f06e508ec928d9ec32cf5 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 5.9E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS17985 c1bd7eba774f06e508ec928d9ec32cf5 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 5.9E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS17985 c1bd7eba774f06e508ec928d9ec32cf5 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS17985 c1bd7eba774f06e508ec928d9ec32cf5 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS17985 c1bd7eba774f06e508ec928d9ec32cf5 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.2E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS17985 c1bd7eba774f06e508ec928d9ec32cf5 250 SUPERFAMILY SSF51735 5 249 5.31E-81 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS17985 c1bd7eba774f06e508ec928d9ec32cf5 250 Gene3D G3DSA:3.40.50.720 1 250 3.0E-72 T 29-03-2018 MC49_RS17985 c1bd7eba774f06e508ec928d9ec32cf5 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 248 1.4E-64 T 29-03-2018 MC49_RS17985 c1bd7eba774f06e508ec928d9ec32cf5 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MC49_RS03110 e73d373d54564bfde82e5c17e57765ad 200 SUPERFAMILY SSF47616 81 197 2.03E-12 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like MC49_RS03110 e73d373d54564bfde82e5c17e57765ad 200 SUPERFAMILY SSF52833 2 84 6.28E-21 T 29-03-2018 IPR012336 Thioredoxin-like fold MC49_RS03110 e73d373d54564bfde82e5c17e57765ad 200 Gene3D G3DSA:3.40.30.10 1 72 1.2E-21 T 29-03-2018 MC49_RS03110 e73d373d54564bfde82e5c17e57765ad 200 Gene3D G3DSA:1.20.1050.10 73 199 1.0E-9 T 29-03-2018 MC49_RS03110 e73d373d54564bfde82e5c17e57765ad 200 Pfam PF02798 Glutathione S-transferase, N-terminal domain 3 74 3.8E-15 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MC49_RS16000 0b8299f44d23d0f5f769f1a1feaeffce 309 Gene3D G3DSA:3.40.50.1980 187 308 1.0E-33 T 29-03-2018 MC49_RS16000 0b8299f44d23d0f5f769f1a1feaeffce 309 Pfam PF01297 Zinc-uptake complex component A periplasmic 42 305 2.9E-80 T 29-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 MC49_RS16000 0b8299f44d23d0f5f769f1a1feaeffce 309 SUPERFAMILY SSF53807 35 307 3.34E-93 T 29-03-2018 MC49_RS16000 0b8299f44d23d0f5f769f1a1feaeffce 309 PRINTS PR00691 Adhesin B signature 83 102 8.9E-38 T 29-03-2018 IPR006129 Adhesin B GO:0007155 MC49_RS16000 0b8299f44d23d0f5f769f1a1feaeffce 309 PRINTS PR00691 Adhesin B signature 220 238 8.9E-38 T 29-03-2018 IPR006129 Adhesin B GO:0007155 MC49_RS16000 0b8299f44d23d0f5f769f1a1feaeffce 309 PRINTS PR00691 Adhesin B signature 39 60 8.9E-38 T 29-03-2018 IPR006129 Adhesin B GO:0007155 MC49_RS16000 0b8299f44d23d0f5f769f1a1feaeffce 309 PRINTS PR00691 Adhesin B signature 64 82 8.9E-38 T 29-03-2018 IPR006129 Adhesin B GO:0007155 MC49_RS16000 0b8299f44d23d0f5f769f1a1feaeffce 309 PRINTS PR00691 Adhesin B signature 194 211 8.9E-38 T 29-03-2018 IPR006129 Adhesin B GO:0007155 MC49_RS16000 0b8299f44d23d0f5f769f1a1feaeffce 309 PRINTS PR00691 Adhesin B signature 243 260 8.9E-38 T 29-03-2018 IPR006129 Adhesin B GO:0007155 MC49_RS16000 0b8299f44d23d0f5f769f1a1feaeffce 309 PRINTS PR00691 Adhesin B signature 265 283 8.9E-38 T 29-03-2018 IPR006129 Adhesin B GO:0007155 MC49_RS16000 0b8299f44d23d0f5f769f1a1feaeffce 309 Gene3D G3DSA:3.40.50.1980 28 186 1.4E-50 T 29-03-2018 MC49_RS16000 0b8299f44d23d0f5f769f1a1feaeffce 309 PRINTS PR00690 Adhesin family signature 247 265 4.6E-44 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 MC49_RS16000 0b8299f44d23d0f5f769f1a1feaeffce 309 PRINTS PR00690 Adhesin family signature 39 57 4.6E-44 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 MC49_RS16000 0b8299f44d23d0f5f769f1a1feaeffce 309 PRINTS PR00690 Adhesin family signature 83 100 4.6E-44 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 MC49_RS16000 0b8299f44d23d0f5f769f1a1feaeffce 309 PRINTS PR00690 Adhesin family signature 194 215 4.6E-44 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 MC49_RS16000 0b8299f44d23d0f5f769f1a1feaeffce 309 PRINTS PR00690 Adhesin family signature 70 83 4.6E-44 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 MC49_RS16000 0b8299f44d23d0f5f769f1a1feaeffce 309 PRINTS PR00690 Adhesin family signature 273 292 4.6E-44 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 MC49_RS10010 513cb253b7c51b000d0a025938243fe0 392 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 213 291 9.2E-12 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MC49_RS10010 513cb253b7c51b000d0a025938243fe0 392 SUPERFAMILY SSF111369 61 114 7.06E-5 T 29-03-2018 MC49_RS10010 513cb253b7c51b000d0a025938243fe0 392 SUPERFAMILY SSF111369 143 182 7.06E-5 T 29-03-2018 MC49_RS10010 513cb253b7c51b000d0a025938243fe0 392 TIGRFAM TIGR00998 8a0101: efflux pump membrane protein 21 346 1.0E-127 T 29-03-2018 IPR005694 Efflux pump membrane protein Emr GO:0006855|GO:0015238 MC49_RS10010 513cb253b7c51b000d0a025938243fe0 392 Gene3D G3DSA:1.20.1600.10 19 313 1.4E-22 T 29-03-2018 MC49_RS10010 513cb253b7c51b000d0a025938243fe0 392 Pfam PF00529 HlyD membrane-fusion protein of T1SS 37 348 6.3E-17 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MC49_RS10010 513cb253b7c51b000d0a025938243fe0 392 SUPERFAMILY SSF111369 195 270 1.03E-7 T 29-03-2018 MC49_RS14840 9c91c543d6efcfbe4685b035f6ccb4a2 361 SUPERFAMILY SSF81345 25 356 3.27E-74 T 29-03-2018 IPR029022 ABC transporter, BtuC-like MC49_RS14840 9c91c543d6efcfbe4685b035f6ccb4a2 361 Pfam PF01032 FecCD transport family 38 356 4.6E-86 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 MC49_RS14840 9c91c543d6efcfbe4685b035f6ccb4a2 361 Gene3D G3DSA:1.10.3470.10 22 361 7.8E-67 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like MC49_RS01990 9edc8f15007c9d0b5b5b220ae025c331 131 SUPERFAMILY SSF69635 15 126 1.05E-13 T 29-03-2018 MC49_RS01990 9edc8f15007c9d0b5b5b220ae025c331 131 Gene3D G3DSA:3.30.1460.10 6 129 2.1E-18 T 29-03-2018 MC49_RS01990 9edc8f15007c9d0b5b5b220ae025c331 131 Pfam PF05932 Tir chaperone protein (CesT) family 14 126 2.5E-13 T 29-03-2018 IPR010261 Tir chaperone protein (CesT) family GO:0005737|GO:0050708 MC49_RS09700 bfce5421c819552b8c0aa98ecf277ff8 248 SUPERFAMILY SSF141523 41 158 7.59E-10 T 29-03-2018 MC49_RS09700 bfce5421c819552b8c0aa98ecf277ff8 248 Gene3D G3DSA:2.40.440.10 36 160 3.2E-7 T 29-03-2018 MC49_RS09700 bfce5421c819552b8c0aa98ecf277ff8 248 Pfam PF03734 L,D-transpeptidase catalytic domain 43 159 6.6E-6 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 MC49_RS10890 15880e3175277d23138b838a4f6a4610 355 Gene3D G3DSA:3.40.50.1000 2 164 1.2E-24 T 29-03-2018 IPR023214 HAD-like domain MC49_RS10890 15880e3175277d23138b838a4f6a4610 355 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 226 239 - T 29-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 MC49_RS10890 15880e3175277d23138b838a4f6a4610 355 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 319 331 - T 29-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 MC49_RS10890 15880e3175277d23138b838a4f6a4610 355 SUPERFAMILY SSF54211 252 342 9.99E-32 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MC49_RS10890 15880e3175277d23138b838a4f6a4610 355 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 167 355 36.451 T 29-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 MC49_RS10890 15880e3175277d23138b838a4f6a4610 355 SUPERFAMILY SSF56784 2 149 1.01E-37 T 29-03-2018 IPR023214 HAD-like domain MC49_RS10890 15880e3175277d23138b838a4f6a4610 355 Gene3D G3DSA:3.30.230.40 255 355 2.4E-31 T 29-03-2018 MC49_RS10890 15880e3175277d23138b838a4f6a4610 355 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 5 144 5.0E-48 T 29-03-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 MC49_RS10890 15880e3175277d23138b838a4f6a4610 355 Pfam PF13242 HAD-hyrolase-like 103 145 1.5E-4 T 29-03-2018 MC49_RS10890 15880e3175277d23138b838a4f6a4610 355 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 196 337 1.3E-63 T 29-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 MC49_RS10890 15880e3175277d23138b838a4f6a4610 355 Hamap MF_01022 Histidine biosynthesis bifunctional protein HisB [hisB]. 2 355 50.958 T 29-03-2018 IPR020566 Histidine biosynthesis bifunctional protein HisB GO:0000105|GO:0004401|GO:0004424 KEGG: 00340+4.2.1.19+3.1.3.15 MC49_RS10890 15880e3175277d23138b838a4f6a4610 355 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 5 145 5.1E-25 T 29-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 MC49_RS10890 15880e3175277d23138b838a4f6a4610 355 Gene3D G3DSA:3.30.230.40 165 253 2.8E-31 T 29-03-2018 MC49_RS10890 15880e3175277d23138b838a4f6a4610 355 SUPERFAMILY SSF54211 167 251 7.59E-30 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MC49_RS10890 15880e3175277d23138b838a4f6a4610 355 TIGRFAM TIGR01261 hisB_Nterm: histidinol-phosphatase 3 162 6.9E-80 T 29-03-2018 IPR005954 Histidinol-phosphatase GO:0000105|GO:0004401|GO:0004424|GO:0005737 KEGG: 00340+4.2.1.19+3.1.3.15 MC49_RS03135 ec4714e9fa2bfb5f33ca588b1a1a9bdc 287 Gene3D G3DSA:3.40.1800.10 160 233 3.0E-8 T 29-03-2018 MC49_RS03135 ec4714e9fa2bfb5f33ca588b1a1a9bdc 287 PIRSF PIRSF030850 1 284 2.3E-105 T 29-03-2018 IPR011396 Uncharacterised conserved protein UCP030850 MC49_RS03135 ec4714e9fa2bfb5f33ca588b1a1a9bdc 287 Pfam PF13391 HNH endonuclease 182 236 1.4E-5 T 29-03-2018 IPR003615 HNH nuclease MC49_RS05445 730070a2cc13ef2cabfce8aebf98b383 620 Pfam PF03144 Elongation factor Tu domain 2 192 259 2.5E-8 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MC49_RS05445 730070a2cc13ef2cabfce8aebf98b383 620 SUPERFAMILY SSF50465 278 358 1.83E-7 T 29-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal MC49_RS05445 730070a2cc13ef2cabfce8aebf98b383 620 Gene3D G3DSA:2.40.30.10 181 283 7.6E-24 T 29-03-2018 MC49_RS05445 730070a2cc13ef2cabfce8aebf98b383 620 Pfam PF09107 Elongation factor SelB, winged helix 571 614 3.1E-19 T 29-03-2018 IPR015191 Translation elongation factor SelB, winged helix, type 3 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 MC49_RS05445 730070a2cc13ef2cabfce8aebf98b383 620 Gene3D G3DSA:1.10.10.10 497 553 1.9E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS05445 730070a2cc13ef2cabfce8aebf98b383 620 Gene3D G3DSA:3.40.50.300 1 180 1.3E-30 T 29-03-2018 MC49_RS05445 730070a2cc13ef2cabfce8aebf98b383 620 SUPERFAMILY SSF46785 425 491 4.9E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS05445 730070a2cc13ef2cabfce8aebf98b383 620 SUPERFAMILY SSF46785 496 555 1.48E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS05445 730070a2cc13ef2cabfce8aebf98b383 620 TIGRFAM TIGR00475 selB: selenocysteine-specific translation elongation factor 1 616 1.2E-192 T 29-03-2018 IPR004535 Translation elongation factor, selenocysteine-specific GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 MC49_RS05445 730070a2cc13ef2cabfce8aebf98b383 620 Gene3D G3DSA:1.10.10.10 556 615 1.9E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS05445 730070a2cc13ef2cabfce8aebf98b383 620 Pfam PF00009 Elongation factor Tu GTP binding domain 3 162 7.2E-27 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS05445 730070a2cc13ef2cabfce8aebf98b383 620 SUPERFAMILY SSF46785 564 616 1.28E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS05445 730070a2cc13ef2cabfce8aebf98b383 620 Gene3D G3DSA:2.40.30.10 284 343 7.5E-10 T 29-03-2018 MC49_RS05445 730070a2cc13ef2cabfce8aebf98b383 620 Gene3D G3DSA:1.10.10.10 425 488 1.9E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS05445 730070a2cc13ef2cabfce8aebf98b383 620 SUPERFAMILY SSF50447 178 296 7.9E-25 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain MC49_RS05445 730070a2cc13ef2cabfce8aebf98b383 620 Pfam PF09106 Elongation factor SelB, winged helix 432 488 1.3E-14 T 29-03-2018 IPR015190 Translation elongation factor SelB, winged helix, type 2 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 MC49_RS05445 730070a2cc13ef2cabfce8aebf98b383 620 SUPERFAMILY SSF52540 2 192 1.43E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS06255 30cdb2622a86c2c2cdfca9b2342a2912 188 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 29 185 3.0E-49 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MC49_RS06255 30cdb2622a86c2c2cdfca9b2342a2912 188 Gene3D G3DSA:2.40.100.10 10 188 1.5E-52 T 29-03-2018 IPR029000 Cyclophilin-like domain MC49_RS06255 30cdb2622a86c2c2cdfca9b2342a2912 188 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 63 80 - T 29-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 MC49_RS06255 30cdb2622a86c2c2cdfca9b2342a2912 188 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 68 80 2.7E-13 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MC49_RS06255 30cdb2622a86c2c2cdfca9b2342a2912 188 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 42 57 2.7E-13 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MC49_RS06255 30cdb2622a86c2c2cdfca9b2342a2912 188 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 142 157 2.7E-13 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MC49_RS06255 30cdb2622a86c2c2cdfca9b2342a2912 188 SUPERFAMILY SSF50891 26 187 4.24E-58 T 29-03-2018 IPR029000 Cyclophilin-like domain MC49_RS06255 30cdb2622a86c2c2cdfca9b2342a2912 188 PIRSF PIRSF001467 13 187 6.3E-29 T 29-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 MC49_RS15355 02896fb17e3754c82d418ba5c23cc20e 447 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 320 424 2.2E-29 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MC49_RS15355 02896fb17e3754c82d418ba5c23cc20e 447 PIRSF PIRSF500134 1 442 9.5E-189 T 29-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 MC49_RS15355 02896fb17e3754c82d418ba5c23cc20e 447 SUPERFAMILY SSF48179 203 300 4.42E-34 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MC49_RS15355 02896fb17e3754c82d418ba5c23cc20e 447 Gene3D G3DSA:1.20.5.170 204 227 1.6E-14 T 29-03-2018 MC49_RS15355 02896fb17e3754c82d418ba5c23cc20e 447 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 420 1.4E-138 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 MC49_RS15355 02896fb17e3754c82d418ba5c23cc20e 447 SUPERFAMILY SSF52413 309 435 5.36E-39 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MC49_RS15355 02896fb17e3754c82d418ba5c23cc20e 447 Gene3D G3DSA:3.40.50.720 228 436 9.2E-72 T 29-03-2018 MC49_RS15355 02896fb17e3754c82d418ba5c23cc20e 447 SUPERFAMILY SSF51735 1 195 1.11E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS15355 02896fb17e3754c82d418ba5c23cc20e 447 Gene3D G3DSA:3.40.50.720 1 202 2.0E-59 T 29-03-2018 MC49_RS15355 02896fb17e3754c82d418ba5c23cc20e 447 SMART SM00984 320 424 9.3E-50 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MC49_RS15355 02896fb17e3754c82d418ba5c23cc20e 447 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 186 7.1E-64 T 29-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MC49_RS15355 02896fb17e3754c82d418ba5c23cc20e 447 PIRSF PIRSF000124 1 439 3.8E-149 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 MC49_RS15355 02896fb17e3754c82d418ba5c23cc20e 447 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 204 296 1.3E-38 T 29-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MC49_RS02055 a8319015849be621c8f6a41f069150bb 316 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 202 215 - T 29-03-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS02055 a8319015849be621c8f6a41f069150bb 316 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 47 62 - T 29-03-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS02055 a8319015849be621c8f6a41f069150bb 316 Pfam PF00146 NADH dehydrogenase 17 311 1.9E-51 T 29-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS10885 320023049b3bc9ebbd9dae0b4311bde1 198 PIRSF PIRSF000495 1 198 2.6E-64 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 MC49_RS10885 320023049b3bc9ebbd9dae0b4311bde1 198 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 3 195 1.5E-65 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 MC49_RS10885 320023049b3bc9ebbd9dae0b4311bde1 198 SUPERFAMILY SSF52317 3 195 6.51E-52 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MC49_RS10885 320023049b3bc9ebbd9dae0b4311bde1 198 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 2 195 33.426 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 MC49_RS10885 320023049b3bc9ebbd9dae0b4311bde1 198 Gene3D G3DSA:3.40.50.880 1 198 2.5E-39 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MC49_RS10885 320023049b3bc9ebbd9dae0b4311bde1 198 Pfam PF00117 Glutamine amidotransferase class-I 35 192 9.8E-17 T 29-03-2018 IPR017926 Glutamine amidotransferase MC49_RS14985 b772a8f60feabfd978ee2a584922c3e1 464 Hamap MF_00743 Fumarate hydratase class II [fumC]. 4 462 93.289 T 29-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MC49_RS14985 b772a8f60feabfd978ee2a584922c3e1 464 Gene3D G3DSA:1.20.200.10 139 417 6.5E-92 T 29-03-2018 MC49_RS14985 b772a8f60feabfd978ee2a584922c3e1 464 SUPERFAMILY SSF48557 4 462 1.49E-160 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 MC49_RS14985 b772a8f60feabfd978ee2a584922c3e1 464 Gene3D G3DSA:1.10.275.10 2 138 4.3E-60 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal MC49_RS14985 b772a8f60feabfd978ee2a584922c3e1 464 ProSitePatterns PS00163 Fumarate lyases signature. 317 326 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 MC49_RS14985 b772a8f60feabfd978ee2a584922c3e1 464 Pfam PF10415 Fumarase C C-terminus 408 461 4.9E-25 T 29-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MC49_RS14985 b772a8f60feabfd978ee2a584922c3e1 464 Pfam PF00206 Lyase 12 342 9.6E-122 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal MC49_RS14985 b772a8f60feabfd978ee2a584922c3e1 464 PRINTS PR00145 Argininosuccinate lyase family signature 175 195 1.1E-5 T 29-03-2018 MC49_RS14985 b772a8f60feabfd978ee2a584922c3e1 464 PRINTS PR00145 Argininosuccinate lyase family signature 317 333 1.1E-5 T 29-03-2018 MC49_RS14985 b772a8f60feabfd978ee2a584922c3e1 464 Gene3D G3DSA:1.10.40.30 418 462 9.3E-26 T 29-03-2018 MC49_RS14985 b772a8f60feabfd978ee2a584922c3e1 464 PRINTS PR00149 Fumarate lyase superfamily signature 134 152 3.9E-34 T 29-03-2018 IPR000362 Fumarate lyase family MC49_RS14985 b772a8f60feabfd978ee2a584922c3e1 464 PRINTS PR00149 Fumarate lyase superfamily signature 271 298 3.9E-34 T 29-03-2018 IPR000362 Fumarate lyase family MC49_RS14985 b772a8f60feabfd978ee2a584922c3e1 464 PRINTS PR00149 Fumarate lyase superfamily signature 180 198 3.9E-34 T 29-03-2018 IPR000362 Fumarate lyase family MC49_RS14985 b772a8f60feabfd978ee2a584922c3e1 464 PRINTS PR00149 Fumarate lyase superfamily signature 317 333 3.9E-34 T 29-03-2018 IPR000362 Fumarate lyase family MC49_RS14985 b772a8f60feabfd978ee2a584922c3e1 464 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 5 461 1.9E-248 T 29-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MC49_RS07525 266c2e8cd52245446d11fd38eeeb68d8 819 Pfam PF00742 Homoserine dehydrogenase 614 810 6.0E-47 T 29-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MC49_RS07525 266c2e8cd52245446d11fd38eeeb68d8 819 Gene3D G3DSA:3.40.1160.10 1 290 6.3E-59 T 29-03-2018 MC49_RS07525 266c2e8cd52245446d11fd38eeeb68d8 819 Pfam PF00696 Amino acid kinase family 2 284 1.1E-42 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MC49_RS07525 266c2e8cd52245446d11fd38eeeb68d8 819 Pfam PF13840 ACT domain 394 448 2.1E-6 T 29-03-2018 IPR027795 GATS-like ACT domain MC49_RS07525 266c2e8cd52245446d11fd38eeeb68d8 819 SUPERFAMILY SSF53633 1 297 5.11E-73 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MC49_RS07525 266c2e8cd52245446d11fd38eeeb68d8 819 SUPERFAMILY SSF55021 383 474 7.01E-22 T 29-03-2018 MC49_RS07525 266c2e8cd52245446d11fd38eeeb68d8 819 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 3 460 1.2E-136 T 29-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 MC49_RS07525 266c2e8cd52245446d11fd38eeeb68d8 819 Gene3D G3DSA:3.40.50.720 465 635 7.4E-28 T 29-03-2018 MC49_RS07525 266c2e8cd52245446d11fd38eeeb68d8 819 SUPERFAMILY SSF51735 464 636 5.13E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS07525 266c2e8cd52245446d11fd38eeeb68d8 819 Gene3D G3DSA:3.30.360.10 636 793 7.2E-52 T 29-03-2018 MC49_RS07525 266c2e8cd52245446d11fd38eeeb68d8 819 SUPERFAMILY SSF55021 303 381 2.61E-22 T 29-03-2018 MC49_RS07525 266c2e8cd52245446d11fd38eeeb68d8 819 PIRSF PIRSF000727 1 817 0.0 T 29-03-2018 IPR011147 Bifunctional aspartokinase/homoserine dehydrogenase I GO:0004072|GO:0004412|GO:0009067|GO:0055114 KEGG: 00260+2.7.2.4+1.1.1.3|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4+1.1.1.3|KEGG: 00300+2.7.2.4+1.1.1.3|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 MC49_RS07525 266c2e8cd52245446d11fd38eeeb68d8 819 Pfam PF01842 ACT domain 324 377 4.9E-11 T 29-03-2018 IPR002912 ACT domain MC49_RS07525 266c2e8cd52245446d11fd38eeeb68d8 819 SUPERFAMILY SSF55347 614 797 1.37E-50 T 29-03-2018 MC49_RS07525 266c2e8cd52245446d11fd38eeeb68d8 819 ProSitePatterns PS00324 Aspartokinase signature. 3 11 - T 29-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 MC49_RS07525 266c2e8cd52245446d11fd38eeeb68d8 819 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 660 682 - T 29-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MC49_RS07525 266c2e8cd52245446d11fd38eeeb68d8 819 Gene3D G3DSA:3.30.70.260 387 464 1.4E-16 T 29-03-2018 MC49_RS07525 266c2e8cd52245446d11fd38eeeb68d8 819 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 472 605 7.4E-28 T 29-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 MC49_RS07525 266c2e8cd52245446d11fd38eeeb68d8 819 Gene3D G3DSA:3.30.70.260 291 386 3.3E-25 T 29-03-2018 MC49_RS06330 42248e7bf3763bc6b5c207e8df53c0d5 617 Pfam PF00999 Sodium/hydrogen exchanger family 13 373 3.5E-67 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 MC49_RS06330 42248e7bf3763bc6b5c207e8df53c0d5 617 Pfam PF02254 TrkA-N domain 404 515 2.3E-22 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MC49_RS06330 42248e7bf3763bc6b5c207e8df53c0d5 617 Gene3D G3DSA:1.20.91.10 229 310 7.5E-11 T 29-03-2018 MC49_RS06330 42248e7bf3763bc6b5c207e8df53c0d5 617 SUPERFAMILY SSF51735 403 530 1.75E-29 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS06330 42248e7bf3763bc6b5c207e8df53c0d5 617 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 16 284 7.3E-86 T 29-03-2018 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 MC49_RS06330 42248e7bf3763bc6b5c207e8df53c0d5 617 Hamap MF_01412 Glutathione-regulated potassium-efflux system protein KefB [kefB]. 4 600 45.721 T 29-03-2018 IPR020884 Glutathione-regulated potassium-efflux system protein KefB GO:0005886|GO:0006813|GO:0015503 MC49_RS06330 42248e7bf3763bc6b5c207e8df53c0d5 617 Gene3D G3DSA:3.40.50.720 398 561 6.2E-19 T 29-03-2018 MC49_RS05970 c96deabfe0bfc5b82006afbe814a1658 466 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 325 2.9E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS05970 c96deabfe0bfc5b82006afbe814a1658 466 SUPERFAMILY SSF55424 345 463 2.23E-30 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 MC49_RS05970 c96deabfe0bfc5b82006afbe814a1658 466 Gene3D G3DSA:3.50.50.60 276 340 9.1E-13 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS05970 c96deabfe0bfc5b82006afbe814a1658 466 Hamap MF_00247 Soluble pyridine nucleotide transhydrogenase [sthA]. 1 466 64.235 T 29-03-2018 IPR022962 Soluble pyridine nucleotide transhydrogenase GO:0003957|GO:0055114 KEGG: 00760+1.6.1.1|MetaCyc: PWY-5083 MC49_RS05970 c96deabfe0bfc5b82006afbe814a1658 466 Gene3D G3DSA:3.50.50.60 2 153 5.2E-23 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS05970 c96deabfe0bfc5b82006afbe814a1658 466 Gene3D G3DSA:3.30.390.30 341 463 1.4E-33 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 MC49_RS05970 c96deabfe0bfc5b82006afbe814a1658 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 40 55 9.2E-51 T 29-03-2018 MC49_RS05970 c96deabfe0bfc5b82006afbe814a1658 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 141 150 9.2E-51 T 29-03-2018 MC49_RS05970 c96deabfe0bfc5b82006afbe814a1658 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 305 312 9.2E-51 T 29-03-2018 MC49_RS05970 c96deabfe0bfc5b82006afbe814a1658 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 9.2E-51 T 29-03-2018 MC49_RS05970 c96deabfe0bfc5b82006afbe814a1658 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 342 363 9.2E-51 T 29-03-2018 MC49_RS05970 c96deabfe0bfc5b82006afbe814a1658 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 177 202 9.2E-51 T 29-03-2018 MC49_RS05970 c96deabfe0bfc5b82006afbe814a1658 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 262 276 9.2E-51 T 29-03-2018 MC49_RS05970 c96deabfe0bfc5b82006afbe814a1658 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 407 422 9.2E-51 T 29-03-2018 MC49_RS05970 c96deabfe0bfc5b82006afbe814a1658 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 432 452 9.2E-51 T 29-03-2018 MC49_RS05970 c96deabfe0bfc5b82006afbe814a1658 466 SUPERFAMILY SSF51905 1 322 4.81E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS05970 c96deabfe0bfc5b82006afbe814a1658 466 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 346 457 1.7E-29 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MC49_RS05970 c96deabfe0bfc5b82006afbe814a1658 466 PIRSF PIRSF000350 1 463 1.7E-68 T 29-03-2018 MC49_RS05970 c96deabfe0bfc5b82006afbe814a1658 466 Gene3D G3DSA:3.50.50.60 154 275 1.8E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS05970 c96deabfe0bfc5b82006afbe814a1658 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 9.2E-28 T 29-03-2018 MC49_RS05970 c96deabfe0bfc5b82006afbe814a1658 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 277 9.2E-28 T 29-03-2018 MC49_RS05970 c96deabfe0bfc5b82006afbe814a1658 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 290 312 9.2E-28 T 29-03-2018 MC49_RS05970 c96deabfe0bfc5b82006afbe814a1658 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 177 195 9.2E-28 T 29-03-2018 MC49_RS05970 c96deabfe0bfc5b82006afbe814a1658 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 138 156 9.2E-28 T 29-03-2018 MC49_RS14595 9efeeceec92c6beda0bff65422b43f9f 1028 Pfam PF00873 AcrB/AcrD/AcrF family 6 1001 3.0E-232 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS14595 9efeeceec92c6beda0bff65422b43f9f 1028 Gene3D G3DSA:3.30.2090.10 182 267 2.0E-11 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MC49_RS14595 9efeeceec92c6beda0bff65422b43f9f 1028 SUPERFAMILY SSF82693 42 135 9.42E-24 T 29-03-2018 MC49_RS14595 9efeeceec92c6beda0bff65422b43f9f 1028 SUPERFAMILY SSF82866 780 1004 3.79E-47 T 29-03-2018 MC49_RS14595 9efeeceec92c6beda0bff65422b43f9f 1028 Gene3D G3DSA:3.30.2090.10 695 784 1.2E-10 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MC49_RS14595 9efeeceec92c6beda0bff65422b43f9f 1028 SUPERFAMILY SSF82693 269 314 1.1E-12 T 29-03-2018 MC49_RS14595 9efeeceec92c6beda0bff65422b43f9f 1028 SUPERFAMILY SSF82693 140 183 1.1E-12 T 29-03-2018 MC49_RS14595 9efeeceec92c6beda0bff65422b43f9f 1028 SUPERFAMILY SSF82714 695 782 6.67E-7 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MC49_RS14595 9efeeceec92c6beda0bff65422b43f9f 1028 Gene3D G3DSA:1.20.1640.10 785 1003 2.3E-41 T 29-03-2018 MC49_RS14595 9efeeceec92c6beda0bff65422b43f9f 1028 Gene3D G3DSA:1.20.1640.10 268 490 6.4E-38 T 29-03-2018 MC49_RS14595 9efeeceec92c6beda0bff65422b43f9f 1028 SUPERFAMILY SSF82866 291 489 2.62E-40 T 29-03-2018 MC49_RS14595 9efeeceec92c6beda0bff65422b43f9f 1028 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 5.2E-56 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS14595 9efeeceec92c6beda0bff65422b43f9f 1028 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 5.2E-56 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS14595 9efeeceec92c6beda0bff65422b43f9f 1028 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 5.2E-56 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS14595 9efeeceec92c6beda0bff65422b43f9f 1028 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 5.2E-56 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS14595 9efeeceec92c6beda0bff65422b43f9f 1028 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 5.2E-56 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS14595 9efeeceec92c6beda0bff65422b43f9f 1028 PRINTS PR00702 Acriflavin resistance protein family signature 536 553 5.2E-56 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS14595 9efeeceec92c6beda0bff65422b43f9f 1028 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 5.2E-56 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS14595 9efeeceec92c6beda0bff65422b43f9f 1028 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 5.2E-56 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS14595 9efeeceec92c6beda0bff65422b43f9f 1028 Gene3D G3DSA:3.30.70.1430 552 648 6.7E-17 T 29-03-2018 MC49_RS14595 9efeeceec92c6beda0bff65422b43f9f 1028 SUPERFAMILY SSF82693 551 645 1.62E-11 T 29-03-2018 MC49_RS14595 9efeeceec92c6beda0bff65422b43f9f 1028 SUPERFAMILY SSF82714 185 265 7.19E-11 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MC49_RS14595 9efeeceec92c6beda0bff65422b43f9f 1028 Gene3D G3DSA:3.30.70.1430 42 142 4.4E-26 T 29-03-2018 MC49_RS07895 dbee33d6ed4db9b93b97ad690e9142e3 1205 Pfam PF12705 PD-(D/E)XK nuclease superfamily 979 1176 2.6E-5 T 29-03-2018 MC49_RS07895 dbee33d6ed4db9b93b97ad690e9142e3 1205 Gene3D G3DSA:1.10.3170.10 157 352 7.1E-60 T 29-03-2018 MC49_RS07895 dbee33d6ed4db9b93b97ad690e9142e3 1205 TIGRFAM TIGR00609 recB: exodeoxyribonuclease V, beta subunit 6 1200 0.0 T 29-03-2018 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 MC49_RS07895 dbee33d6ed4db9b93b97ad690e9142e3 1205 Pfam PF00580 UvrD/REP helicase N-terminal domain 4 448 1.1E-60 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 MC49_RS07895 dbee33d6ed4db9b93b97ad690e9142e3 1205 SUPERFAMILY SSF52540 14 77 6.35E-111 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS07895 dbee33d6ed4db9b93b97ad690e9142e3 1205 SUPERFAMILY SSF52540 120 204 6.35E-111 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS07895 dbee33d6ed4db9b93b97ad690e9142e3 1205 SUPERFAMILY SSF52540 328 830 6.35E-111 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS07895 dbee33d6ed4db9b93b97ad690e9142e3 1205 Gene3D G3DSA:3.90.320.10 902 1205 1.9E-78 T 29-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 MC49_RS07895 dbee33d6ed4db9b93b97ad690e9142e3 1205 SUPERFAMILY SSF52980 913 1202 6.43E-85 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MC49_RS07895 dbee33d6ed4db9b93b97ad690e9142e3 1205 Pfam PF13361 UvrD-like helicase C-terminal domain 453 820 2.6E-21 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MC49_RS07895 dbee33d6ed4db9b93b97ad690e9142e3 1205 Hamap MF_01485 RecBCD enzyme subunit RecB [recB]. 4 1201 22.964 T 29-03-2018 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 MC49_RS07895 dbee33d6ed4db9b93b97ad690e9142e3 1205 Gene3D G3DSA:3.40.50.300 455 603 9.6E-21 T 29-03-2018 MC49_RS07895 dbee33d6ed4db9b93b97ad690e9142e3 1205 Gene3D G3DSA:3.40.50.300 611 893 6.3E-28 T 29-03-2018 MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 SUPERFAMILY SSF50249 103 185 7.15E-15 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 Gene3D G3DSA:2.40.50.140 451 550 4.0E-19 T 29-03-2018 MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 SUPERFAMILY SSF50249 429 535 1.79E-21 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 SUPERFAMILY SSF50249 255 371 2.2E-30 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 Gene3D G3DSA:2.40.50.140 274 348 2.2E-26 T 29-03-2018 MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 Gene3D G3DSA:2.40.50.140 361 435 2.3E-20 T 29-03-2018 MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 SUPERFAMILY SSF50249 362 443 1.64E-20 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 SUPERFAMILY SSF50249 2 112 5.72E-19 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 3 520 2.9E-239 T 29-03-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 PRINTS PR00681 Ribosomal protein S1 signature 155 175 3.4E-99 T 29-03-2018 MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 PRINTS PR00681 Ribosomal protein S1 signature 21 39 3.4E-99 T 29-03-2018 MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 PRINTS PR00681 Ribosomal protein S1 signature 330 348 3.4E-99 T 29-03-2018 MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 PRINTS PR00681 Ribosomal protein S1 signature 84 103 3.4E-99 T 29-03-2018 MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 PRINTS PR00681 Ribosomal protein S1 signature 126 143 3.4E-99 T 29-03-2018 MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 PRINTS PR00681 Ribosomal protein S1 signature 39 53 3.4E-99 T 29-03-2018 MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 PRINTS PR00681 Ribosomal protein S1 signature 212 233 3.4E-99 T 29-03-2018 MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 PRINTS PR00681 Ribosomal protein S1 signature 290 309 3.4E-99 T 29-03-2018 MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 PRINTS PR00681 Ribosomal protein S1 signature 108 124 3.4E-99 T 29-03-2018 MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 Pfam PF00575 S1 RNA binding domain 19 86 2.5E-7 T 29-03-2018 IPR003029 S1 domain GO:0003676 MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 Pfam PF00575 S1 RNA binding domain 190 260 2.4E-21 T 29-03-2018 IPR003029 S1 domain GO:0003676 MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 Pfam PF00575 S1 RNA binding domain 361 434 9.5E-22 T 29-03-2018 IPR003029 S1 domain GO:0003676 MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 Pfam PF00575 S1 RNA binding domain 275 347 4.9E-20 T 29-03-2018 IPR003029 S1 domain GO:0003676 MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 Pfam PF00575 S1 RNA binding domain 103 171 6.3E-11 T 29-03-2018 IPR003029 S1 domain GO:0003676 MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 Pfam PF00575 S1 RNA binding domain 449 520 3.5E-16 T 29-03-2018 IPR003029 S1 domain GO:0003676 MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 PIRSF PIRSF002111 1 534 6.6E-220 T 29-03-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 SMART SM00316 449 520 1.9E-21 T 29-03-2018 IPR022967 RNA-binding domain, S1 MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 SMART SM00316 190 260 2.8E-28 T 29-03-2018 IPR022967 RNA-binding domain, S1 MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 SMART SM00316 19 87 1.9E-5 T 29-03-2018 IPR022967 RNA-binding domain, S1 MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 SMART SM00316 103 171 3.2E-9 T 29-03-2018 IPR022967 RNA-binding domain, S1 MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 SMART SM00316 362 434 3.4E-21 T 29-03-2018 IPR022967 RNA-binding domain, S1 MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 SMART SM00316 275 347 6.8E-27 T 29-03-2018 IPR022967 RNA-binding domain, S1 MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 Gene3D G3DSA:2.40.50.140 1 92 2.6E-8 T 29-03-2018 MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 SUPERFAMILY SSF50249 189 276 5.3E-27 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 Gene3D G3DSA:2.40.50.140 182 266 2.5E-26 T 29-03-2018 MC49_RS11130 c295a40eb05fb89a26ad124feba2e1a4 557 Gene3D G3DSA:2.40.50.140 95 177 2.7E-8 T 29-03-2018 MC49_RS04260 c5e19db419e4161b1d3f1a937f1979e4 366 TIGRFAM TIGR02143 trmA_only: tRNA (uracil(54)-C(5))-methyltransferase 9 365 2.8E-182 T 29-03-2018 IPR011869 tRNA/tmRNA (uracil-C(5))-methyltransferase, TrmA GO:0006396|GO:0030697 MC49_RS04260 c5e19db419e4161b1d3f1a937f1979e4 366 Gene3D G3DSA:3.40.50.150 164 365 2.3E-33 T 29-03-2018 MC49_RS04260 c5e19db419e4161b1d3f1a937f1979e4 366 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 347 357 - T 29-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site MC49_RS04260 c5e19db419e4161b1d3f1a937f1979e4 366 Hamap MF_01011 tRNA/tmRNA (uracil-C(5))-methyltransferase [trmA]. 3 365 42.093 T 29-03-2018 IPR011869 tRNA/tmRNA (uracil-C(5))-methyltransferase, TrmA GO:0006396|GO:0030697 MC49_RS04260 c5e19db419e4161b1d3f1a937f1979e4 366 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 298 327 - T 29-03-2018 IPR030390 RNA methyltransferase TrmA, active site MC49_RS04260 c5e19db419e4161b1d3f1a937f1979e4 366 SUPERFAMILY SSF53335 5 364 1.13E-51 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS04260 c5e19db419e4161b1d3f1a937f1979e4 366 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 9 364 6.7E-187 T 29-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 MC49_RS02635 6331e661d99e02bdb4da6ec2d7e26851 279 Pfam PF13649 Methyltransferase domain 64 149 1.5E-14 T 29-03-2018 MC49_RS02635 6331e661d99e02bdb4da6ec2d7e26851 279 Gene3D G3DSA:3.40.50.150 12 173 1.5E-20 T 29-03-2018 MC49_RS02635 6331e661d99e02bdb4da6ec2d7e26851 279 SUPERFAMILY SSF53335 20 152 5.43E-25 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS02665 8dbf894f09d6ce7887541b18c89c710c 346 SUPERFAMILY SSF82861 78 161 5.62E-10 T 29-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 MC49_RS02665 8dbf894f09d6ce7887541b18c89c710c 346 Gene3D G3DSA:2.30.30.60 179 229 9.6E-14 T 29-03-2018 MC49_RS02665 8dbf894f09d6ce7887541b18c89c710c 346 Pfam PF00924 Mechanosensitive ion channel 121 324 3.2E-61 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MC49_RS02665 8dbf894f09d6ce7887541b18c89c710c 346 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 195 229 - T 29-03-2018 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 MC49_RS02665 8dbf894f09d6ce7887541b18c89c710c 346 SUPERFAMILY SSF50182 163 229 5.89E-17 T 29-03-2018 IPR010920 LSM domain MC49_RS02665 8dbf894f09d6ce7887541b18c89c710c 346 Gene3D G3DSA:3.30.70.100 231 330 1.2E-19 T 29-03-2018 MC49_RS02665 8dbf894f09d6ce7887541b18c89c710c 346 SUPERFAMILY SSF82689 232 335 1.83E-20 T 29-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 MC49_RS10395 bbbac2e605ed64bbc90e317096d7a26b 290 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 236 249 - T 29-03-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site MC49_RS10395 bbbac2e605ed64bbc90e317096d7a26b 290 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 2.4E-39 T 29-03-2018 MC49_RS10395 bbbac2e605ed64bbc90e317096d7a26b 290 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 2.4E-39 T 29-03-2018 MC49_RS10395 bbbac2e605ed64bbc90e317096d7a26b 290 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 2.4E-39 T 29-03-2018 MC49_RS10395 bbbac2e605ed64bbc90e317096d7a26b 290 PRINTS PR01798 Succinyl-CoA synthase signature 240 257 2.4E-39 T 29-03-2018 MC49_RS10395 bbbac2e605ed64bbc90e317096d7a26b 290 Gene3D G3DSA:3.40.50.261 120 290 5.3E-57 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MC49_RS10395 bbbac2e605ed64bbc90e317096d7a26b 290 PIRSF PIRSF001553 1 290 2.7E-135 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MC49_RS10395 bbbac2e605ed64bbc90e317096d7a26b 290 Pfam PF00549 CoA-ligase 151 271 2.3E-21 T 29-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MC49_RS10395 bbbac2e605ed64bbc90e317096d7a26b 290 SMART SM00881 4 100 5.2E-38 T 29-03-2018 IPR003781 CoA-binding GO:0048037 MC49_RS10395 bbbac2e605ed64bbc90e317096d7a26b 290 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 288 43.325 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MC49_RS10395 bbbac2e605ed64bbc90e317096d7a26b 290 SUPERFAMILY SSF52210 123 287 2.22E-57 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MC49_RS10395 bbbac2e605ed64bbc90e317096d7a26b 290 Pfam PF02629 CoA binding domain 6 99 1.6E-31 T 29-03-2018 IPR003781 CoA-binding GO:0048037 MC49_RS10395 bbbac2e605ed64bbc90e317096d7a26b 290 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 288 4.1E-146 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MC49_RS10395 bbbac2e605ed64bbc90e317096d7a26b 290 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 29-03-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site MC49_RS10395 bbbac2e605ed64bbc90e317096d7a26b 290 SUPERFAMILY SSF51735 1 122 8.72E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS10395 bbbac2e605ed64bbc90e317096d7a26b 290 Gene3D G3DSA:3.40.50.720 1 119 8.2E-45 T 29-03-2018 MC49_RS12160 e238dd65eaabc23e38f3106a94aad63f 769 Gene3D G3DSA:1.10.3810.10 40 241 8.7E-60 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 MC49_RS12160 e238dd65eaabc23e38f3106a94aad63f 769 SUPERFAMILY SSF53955 41 256 5.91E-65 T 29-03-2018 IPR023346 Lysozyme-like domain MC49_RS12160 e238dd65eaabc23e38f3106a94aad63f 769 Pfam PF00905 Penicillin binding protein transpeptidase domain 303 526 1.4E-12 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MC49_RS12160 e238dd65eaabc23e38f3106a94aad63f 769 Gene3D G3DSA:3.40.710.10 249 605 1.6E-64 T 29-03-2018 MC49_RS12160 e238dd65eaabc23e38f3106a94aad63f 769 SUPERFAMILY SSF56601 255 633 5.03E-91 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MC49_RS12160 e238dd65eaabc23e38f3106a94aad63f 769 SUPERFAMILY SSF56601 206 228 5.03E-91 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MC49_RS12160 e238dd65eaabc23e38f3106a94aad63f 769 TIGRFAM TIGR02073 PBP_1c: penicillin-binding protein 1C 38 767 6.2E-239 T 29-03-2018 IPR011815 Penicillin-binding protein 1C GO:0008955|GO:0009252 MC49_RS12160 e238dd65eaabc23e38f3106a94aad63f 769 Pfam PF00912 Transglycosylase 58 224 1.9E-52 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 MC49_RS12160 e238dd65eaabc23e38f3106a94aad63f 769 Pfam PF06832 Penicillin-Binding Protein C-terminus Family 685 766 2.9E-14 T 29-03-2018 IPR009647 Penicillin-binding, C-terminal MC49_RS02495 96f3431cacb50bb8f851d5211a115602 2425 SMART SM00869 2146 2413 5.8E-33 T 29-03-2018 IPR005546 Autotransporter beta-domain MC49_RS02495 96f3431cacb50bb8f851d5211a115602 2425 Gene3D G3DSA:2.40.128.130 2104 2424 8.8E-53 T 29-03-2018 MC49_RS02495 96f3431cacb50bb8f851d5211a115602 2425 SUPERFAMILY SSF51126 1613 2086 2.04E-26 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor MC49_RS02495 96f3431cacb50bb8f851d5211a115602 2425 SUPERFAMILY SSF103515 2112 2424 2.75E-46 T 29-03-2018 IPR005546 Autotransporter beta-domain MC49_RS02495 96f3431cacb50bb8f851d5211a115602 2425 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 1976 2424 8.7E-80 T 29-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 MC49_RS02495 96f3431cacb50bb8f851d5211a115602 2425 Gene3D G3DSA:2.160.20.20 602 797 0.0023 T 29-03-2018 IPR012332 P22 tailspike C-terminal domain-like MC49_RS02495 96f3431cacb50bb8f851d5211a115602 2425 Gene3D G3DSA:2.160.20.20 1573 2089 1.5E-33 T 29-03-2018 IPR012332 P22 tailspike C-terminal domain-like MC49_RS02495 96f3431cacb50bb8f851d5211a115602 2425 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 1868 1900 5.1E-5 T 29-03-2018 IPR013425 Autotransporter-associated beta strand repeat MC49_RS02495 96f3431cacb50bb8f851d5211a115602 2425 Pfam PF03797 Autotransporter beta-domain 2149 2402 2.6E-44 T 29-03-2018 IPR005546 Autotransporter beta-domain MC49_RS04145 099a99e3c156e38e983bce8a2659c9ea 274 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 249 3.2E-56 T 29-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 MC49_RS04145 099a99e3c156e38e983bce8a2659c9ea 274 SMART SM01383 42 118 1.4E-48 T 29-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS04145 099a99e3c156e38e983bce8a2659c9ea 274 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 272 6.7E-131 T 29-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 MC49_RS04145 099a99e3c156e38e983bce8a2659c9ea 274 SUPERFAMILY SSF50249 2 125 2.4E-50 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS04145 099a99e3c156e38e983bce8a2659c9ea 274 Gene3D G3DSA:4.10.950.10 197 272 1.6E-34 T 29-03-2018 IPR014726 Ribosomal protein L2, domain 3 MC49_RS04145 099a99e3c156e38e983bce8a2659c9ea 274 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 29-03-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04145 099a99e3c156e38e983bce8a2659c9ea 274 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 272 46.945 T 29-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 MC49_RS04145 099a99e3c156e38e983bce8a2659c9ea 274 Gene3D G3DSA:2.40.50.140 1 114 1.3E-48 T 29-03-2018 MC49_RS04145 099a99e3c156e38e983bce8a2659c9ea 274 SUPERFAMILY SSF50104 127 269 5.66E-60 T 29-03-2018 IPR008991 Translation protein SH3-like domain MC49_RS04145 099a99e3c156e38e983bce8a2659c9ea 274 Gene3D G3DSA:2.30.30.30 119 195 4.9E-32 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 MC49_RS04145 099a99e3c156e38e983bce8a2659c9ea 274 SMART SM01382 124 251 8.4E-91 T 29-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 MC49_RS04145 099a99e3c156e38e983bce8a2659c9ea 274 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 2.3E-34 T 29-03-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS04145 099a99e3c156e38e983bce8a2659c9ea 274 PIRSF PIRSF002158 12 274 4.7E-101 T 29-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS03425 a17c42a093a5cb1baa95a33509050504 97 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 3 94 6.0E-35 T 29-03-2018 IPR017924 RNA-binding protein YhbY GO:0003723 MC49_RS03425 a17c42a093a5cb1baa95a33509050504 97 SUPERFAMILY SSF75471 1 95 2.75E-30 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 MC49_RS03425 a17c42a093a5cb1baa95a33509050504 97 Gene3D G3DSA:3.30.110.60 2 97 3.5E-26 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 MC49_RS03425 a17c42a093a5cb1baa95a33509050504 97 SMART SM01103 3 86 1.1E-39 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 MC49_RS03425 a17c42a093a5cb1baa95a33509050504 97 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 9 96 2.0E-36 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 MC49_RS03425 a17c42a093a5cb1baa95a33509050504 97 Pfam PF01985 CRS1 / YhbY (CRM) domain 3 86 7.7E-21 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 MC49_RS09190 bc90793df60187d6aeffd468b409b266 545 SUPERFAMILY SSF52317 289 540 5.66E-87 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MC49_RS09190 bc90793df60187d6aeffd468b409b266 545 Hamap MF_01227 CTP synthase [pyrG]. 3 540 51.297 T 29-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 MC49_RS09190 bc90793df60187d6aeffd468b409b266 545 Pfam PF06418 CTP synthase N-terminus 5 265 1.3E-125 T 29-03-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 MC49_RS09190 bc90793df60187d6aeffd468b409b266 545 Gene3D G3DSA:3.40.50.300 1 285 8.6E-129 T 29-03-2018 MC49_RS09190 bc90793df60187d6aeffd468b409b266 545 Gene3D G3DSA:3.40.50.880 286 543 5.1E-73 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MC49_RS09190 bc90793df60187d6aeffd468b409b266 545 Pfam PF00117 Glutamine amidotransferase class-I 301 535 3.9E-62 T 29-03-2018 IPR017926 Glutamine amidotransferase MC49_RS09190 bc90793df60187d6aeffd468b409b266 545 TIGRFAM TIGR00337 PyrG: CTP synthase 2 535 1.1E-263 T 29-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 MC49_RS09190 bc90793df60187d6aeffd468b409b266 545 SUPERFAMILY SSF52540 3 269 2.08E-122 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS15290 0fef3b42bc56d2f38625b144b76af761 546 Gene3D G3DSA:3.90.76.10 65 177 1.4E-29 T 29-03-2018 MC49_RS15290 0fef3b42bc56d2f38625b144b76af761 546 Gene3D G3DSA:3.40.190.10 178 313 5.2E-35 T 29-03-2018 MC49_RS15290 0fef3b42bc56d2f38625b144b76af761 546 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 85 465 1.8E-81 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain MC49_RS15290 0fef3b42bc56d2f38625b144b76af761 546 SUPERFAMILY SSF53850 37 528 4.21E-137 T 29-03-2018 MC49_RS15290 0fef3b42bc56d2f38625b144b76af761 546 PIRSF PIRSF002741 3 546 2.7E-103 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MC49_RS15290 0fef3b42bc56d2f38625b144b76af761 546 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 89 110 - T 29-03-2018 IPR023765 Solute-binding protein family 5, conserved site MC49_RS15290 0fef3b42bc56d2f38625b144b76af761 546 Gene3D G3DSA:3.10.105.10 314 515 2.5E-52 T 29-03-2018 MC49_RS16310 7d677ab862e443749cdba9a22c47d4cb 453 Gene3D G3DSA:3.30.565.10 300 453 1.0E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS16310 7d677ab862e443749cdba9a22c47d4cb 453 SMART SM00304 179 231 4.3E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MC49_RS16310 7d677ab862e443749cdba9a22c47d4cb 453 SMART SM00388 232 296 1.6E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS16310 7d677ab862e443749cdba9a22c47d4cb 453 Gene3D G3DSA:1.10.287.130 222 291 4.1E-12 T 29-03-2018 MC49_RS16310 7d677ab862e443749cdba9a22c47d4cb 453 SUPERFAMILY SSF55874 286 451 7.86E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS16310 7d677ab862e443749cdba9a22c47d4cb 453 Pfam PF00512 His Kinase A (phospho-acceptor) domain 233 295 5.4E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS16310 7d677ab862e443749cdba9a22c47d4cb 453 SUPERFAMILY SSF47384 215 296 5.3E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS16310 7d677ab862e443749cdba9a22c47d4cb 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 378 392 1.7E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS16310 7d677ab862e443749cdba9a22c47d4cb 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 406 1.7E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS16310 7d677ab862e443749cdba9a22c47d4cb 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 450 1.7E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS16310 7d677ab862e443749cdba9a22c47d4cb 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 431 1.7E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS16310 7d677ab862e443749cdba9a22c47d4cb 453 SUPERFAMILY SSF158472 180 227 2.62E-10 T 29-03-2018 MC49_RS16310 7d677ab862e443749cdba9a22c47d4cb 453 Pfam PF00672 HAMP domain 181 227 4.9E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MC49_RS16310 7d677ab862e443749cdba9a22c47d4cb 453 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 341 451 1.0E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS16310 7d677ab862e443749cdba9a22c47d4cb 453 SMART SM00387 341 453 1.6E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS16125 ac0db20ceac3810bb6c1f18bc2adf013 265 Gene3D G3DSA:3.30.540.10 3 157 1.9E-33 T 29-03-2018 MC49_RS16125 ac0db20ceac3810bb6c1f18bc2adf013 265 Gene3D G3DSA:3.40.190.80 158 265 2.0E-19 T 29-03-2018 MC49_RS16125 ac0db20ceac3810bb6c1f18bc2adf013 265 Pfam PF00459 Inositol monophosphatase family 8 258 1.1E-40 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MC49_RS16125 ac0db20ceac3810bb6c1f18bc2adf013 265 SUPERFAMILY SSF56655 5 263 1.3E-61 T 29-03-2018 MC49_RS16125 ac0db20ceac3810bb6c1f18bc2adf013 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 181 202 5.7E-23 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MC49_RS16125 ac0db20ceac3810bb6c1f18bc2adf013 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 86 102 5.7E-23 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MC49_RS16125 ac0db20ceac3810bb6c1f18bc2adf013 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 45 65 5.7E-23 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MC49_RS16125 ac0db20ceac3810bb6c1f18bc2adf013 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 67 83 5.7E-23 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MC49_RS16125 ac0db20ceac3810bb6c1f18bc2adf013 265 PRINTS PR00377 Inositol monophosphatase superfamily signature 212 236 5.7E-23 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MC49_RS02925 4f0ca232460695e2262040acaee47b79 1253 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 2 1237 0.0 T 29-03-2018 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 MC49_RS02925 4f0ca232460695e2262040acaee47b79 1253 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 48 66 - T 29-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 MC49_RS02925 4f0ca232460695e2262040acaee47b79 1253 Gene3D G3DSA:3.40.50.740 108 213 1.0E-4 T 29-03-2018 MC49_RS02925 4f0ca232460695e2262040acaee47b79 1253 Pfam PF00384 Molybdopterin oxidoreductase 108 834 1.6E-167 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS02925 4f0ca232460695e2262040acaee47b79 1253 Pfam PF14710 Respiratory nitrate reductase alpha N-terminal 3 40 3.2E-14 T 29-03-2018 IPR028189 Nitrate reductase, alpha subunit, N-terminal KEGG: 00910+1.7.99.4 MC49_RS02925 4f0ca232460695e2262040acaee47b79 1253 Gene3D G3DSA:3.40.228.10 225 662 8.7E-100 T 29-03-2018 MC49_RS02925 4f0ca232460695e2262040acaee47b79 1253 Gene3D G3DSA:3.30.2070.10 797 837 3.8E-5 T 29-03-2018 MC49_RS02925 4f0ca232460695e2262040acaee47b79 1253 Gene3D G3DSA:2.20.25.90 55 98 1.4E-28 T 29-03-2018 MC49_RS02925 4f0ca232460695e2262040acaee47b79 1253 SUPERFAMILY SSF53706 4 1072 0.0 T 29-03-2018 MC49_RS02925 4f0ca232460695e2262040acaee47b79 1253 SUPERFAMILY SSF50692 1085 1239 1.11E-46 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain MC49_RS02925 4f0ca232460695e2262040acaee47b79 1253 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 779 796 - T 29-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 MC49_RS02925 4f0ca232460695e2262040acaee47b79 1253 Gene3D G3DSA:4.10.1200.10 1 26 3.1E-12 T 29-03-2018 MC49_RS02925 4f0ca232460695e2262040acaee47b79 1253 SMART SM00926 43 105 4.1E-8 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS02925 4f0ca232460695e2262040acaee47b79 1253 Gene3D G3DSA:2.40.40.20 1050 1240 9.6E-47 T 29-03-2018 MC49_RS02925 4f0ca232460695e2262040acaee47b79 1253 Pfam PF01568 Molydopterin dinucleotide binding domain 1090 1203 4.2E-21 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 MC49_RS03175 baeb7042f12b679cc5170dcde3db594d 344 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 76 255 2.8E-23 T 29-03-2018 IPR000477 Reverse transcriptase domain MC49_RS03175 baeb7042f12b679cc5170dcde3db594d 344 SUPERFAMILY SSF56672 67 253 3.24E-13 T 29-03-2018 MC49_RS03175 baeb7042f12b679cc5170dcde3db594d 344 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 179 192 6.7E-34 T 29-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MC49_RS03175 baeb7042f12b679cc5170dcde3db594d 344 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 71 84 6.7E-34 T 29-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MC49_RS03175 baeb7042f12b679cc5170dcde3db594d 344 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 85 97 6.7E-34 T 29-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MC49_RS03175 baeb7042f12b679cc5170dcde3db594d 344 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 116 130 6.7E-34 T 29-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MC49_RS03175 baeb7042f12b679cc5170dcde3db594d 344 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 197 210 6.7E-34 T 29-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MC49_RS03175 baeb7042f12b679cc5170dcde3db594d 344 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 132 150 6.7E-34 T 29-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MC49_RS03175 baeb7042f12b679cc5170dcde3db594d 344 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 262 268 6.7E-34 T 29-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MC49_RS03175 baeb7042f12b679cc5170dcde3db594d 344 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 212 223 6.7E-34 T 29-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 MC49_RS03175 baeb7042f12b679cc5170dcde3db594d 344 Gene3D G3DSA:3.30.70.270 94 267 1.5E-22 T 29-03-2018 MC49_RS11600 5f84ee97e0c4bb0263f4a887b6bcfd93 1184 Gene3D G3DSA:3.40.50.970 794 1171 1.4E-98 T 29-03-2018 MC49_RS11600 5f84ee97e0c4bb0263f4a887b6bcfd93 1184 Gene3D G3DSA:4.10.780.10 634 668 3.2E-17 T 29-03-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 MC49_RS11600 5f84ee97e0c4bb0263f4a887b6bcfd93 1184 Pfam PF10371 Domain of unknown function 627 678 1.0E-24 T 29-03-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 MC49_RS11600 5f84ee97e0c4bb0263f4a887b6bcfd93 1184 Gene3D G3DSA:3.40.50.970 1 254 7.4E-47 T 29-03-2018 MC49_RS11600 5f84ee97e0c4bb0263f4a887b6bcfd93 1184 PIRSF PIRSF000159 1 1176 0.0 T 29-03-2018 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 MC49_RS11600 5f84ee97e0c4bb0263f4a887b6bcfd93 1184 SUPERFAMILY SSF52922 256 406 1.73E-39 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MC49_RS11600 5f84ee97e0c4bb0263f4a887b6bcfd93 1184 Gene3D G3DSA:3.40.920.10 417 623 1.4E-52 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 MC49_RS11600 5f84ee97e0c4bb0263f4a887b6bcfd93 1184 Pfam PF12838 4Fe-4S dicluster domain 689 757 9.4E-10 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MC49_RS11600 5f84ee97e0c4bb0263f4a887b6bcfd93 1184 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 265 347 1.0E-12 T 29-03-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II MC49_RS11600 5f84ee97e0c4bb0263f4a887b6bcfd93 1184 SUPERFAMILY SSF52518 796 1164 4.42E-114 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MC49_RS11600 5f84ee97e0c4bb0263f4a887b6bcfd93 1184 SUPERFAMILY SSF52518 2 254 3.83E-70 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MC49_RS11600 5f84ee97e0c4bb0263f4a887b6bcfd93 1184 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 14 243 3.4E-78 T 29-03-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 MC49_RS11600 5f84ee97e0c4bb0263f4a887b6bcfd93 1184 TIGRFAM TIGR02176 pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase 1 1168 0.0 T 29-03-2018 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 MC49_RS11600 5f84ee97e0c4bb0263f4a887b6bcfd93 1184 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 745 756 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MC49_RS11600 5f84ee97e0c4bb0263f4a887b6bcfd93 1184 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 958 1069 8.6E-10 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MC49_RS11600 5f84ee97e0c4bb0263f4a887b6bcfd93 1184 Gene3D G3DSA:3.30.70.20 669 791 1.8E-29 T 29-03-2018 MC49_RS11600 5f84ee97e0c4bb0263f4a887b6bcfd93 1184 Gene3D G3DSA:3.40.50.920 255 412 2.5E-39 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MC49_RS11600 5f84ee97e0c4bb0263f4a887b6bcfd93 1184 SUPERFAMILY SSF53323 418 668 9.15E-75 T 29-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 MC49_RS11600 5f84ee97e0c4bb0263f4a887b6bcfd93 1184 SMART SM00890 622 679 1.3E-30 T 29-03-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 MC49_RS11600 5f84ee97e0c4bb0263f4a887b6bcfd93 1184 SUPERFAMILY SSF54862 665 838 4.74E-22 T 29-03-2018 MC49_RS11600 5f84ee97e0c4bb0263f4a887b6bcfd93 1184 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 426 606 7.5E-32 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 MC49_RS09570 51e10d55b90cbf52b88df5fb2c124fa1 345 SMART SM00478 39 190 3.4E-50 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MC49_RS09570 51e10d55b90cbf52b88df5fb2c124fa1 345 SUPERFAMILY SSF55811 220 343 2.23E-24 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MC49_RS09570 51e10d55b90cbf52b88df5fb2c124fa1 345 Gene3D G3DSA:3.90.79.10 224 343 7.9E-8 T 29-03-2018 MC49_RS09570 51e10d55b90cbf52b88df5fb2c124fa1 345 SUPERFAMILY SSF48150 3 225 2.51E-77 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 MC49_RS09570 51e10d55b90cbf52b88df5fb2c124fa1 345 SMART SM00525 191 211 2.1E-5 T 29-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 MC49_RS09570 51e10d55b90cbf52b88df5fb2c124fa1 345 Pfam PF00633 Helix-hairpin-helix motif 99 127 5.4E-8 T 29-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 MC49_RS09570 51e10d55b90cbf52b88df5fb2c124fa1 345 Pfam PF14815 NUDIX domain 233 343 7.4E-24 T 29-03-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 MC49_RS09570 51e10d55b90cbf52b88df5fb2c124fa1 345 Gene3D G3DSA:1.10.340.30 21 118 1.2E-31 T 29-03-2018 MC49_RS09570 51e10d55b90cbf52b88df5fb2c124fa1 345 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 5 277 8.1E-129 T 29-03-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 MC49_RS09570 51e10d55b90cbf52b88df5fb2c124fa1 345 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 36 167 2.3E-22 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MC49_RS09570 51e10d55b90cbf52b88df5fb2c124fa1 345 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 192 208 - T 29-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 MC49_RS09570 51e10d55b90cbf52b88df5fb2c124fa1 345 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 192 208 6.0E-5 T 29-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 MC49_RS09570 51e10d55b90cbf52b88df5fb2c124fa1 345 Gene3D G3DSA:1.10.1670.10 119 223 5.5E-34 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 MC49_RS06950 07fbef4ec0a35823e1716e2400ddbaa1 63 Pfam PF13438 Domain of unknown function (DUF4113) 13 61 3.5E-16 T 29-03-2018 IPR025188 Domain of unknown function DUF4113 MC49_RS03340 68ed597276081a8afa4299b52b63212e 237 Gene3D G3DSA:3.40.50.2300 1 131 1.8E-28 T 29-03-2018 MC49_RS03340 68ed597276081a8afa4299b52b63212e 237 SMART SM00448 1 111 2.1E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS03340 68ed597276081a8afa4299b52b63212e 237 Pfam PF00072 Response regulator receiver domain 3 111 4.1E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS03340 68ed597276081a8afa4299b52b63212e 237 SUPERFAMILY SSF52172 1 134 4.84E-31 T 29-03-2018 IPR011006 CheY-like superfamily MC49_RS03340 68ed597276081a8afa4299b52b63212e 237 SMART SM00850 140 235 2.5E-25 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 MC49_RS03340 68ed597276081a8afa4299b52b63212e 237 Gene3D G3DSA:2.40.50.40 132 197 6.1E-6 T 29-03-2018 MC49_RS03340 68ed597276081a8afa4299b52b63212e 237 Pfam PF04397 LytTr DNA-binding domain 141 234 5.4E-23 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 MC49_RS03340 68ed597276081a8afa4299b52b63212e 237 Gene3D G3DSA:2.20.25.10 200 235 1.9E-8 T 29-03-2018 MC49_RS10390 a6d83d740a234f78cde82c799d5765cb 388 SUPERFAMILY SSF52210 240 385 5.36E-52 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MC49_RS10390 a6d83d740a234f78cde82c799d5765cb 388 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 42.935 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MC49_RS10390 a6d83d740a234f78cde82c799d5765cb 388 SUPERFAMILY SSF56059 1 238 2.42E-80 T 29-03-2018 MC49_RS10390 a6d83d740a234f78cde82c799d5765cb 388 Pfam PF08442 ATP-grasp domain 2 203 8.1E-81 T 29-03-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MC49_RS10390 a6d83d740a234f78cde82c799d5765cb 388 Gene3D G3DSA:3.40.50.261 240 385 6.9E-41 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MC49_RS10390 a6d83d740a234f78cde82c799d5765cb 388 Pfam PF00549 CoA-ligase 262 381 1.2E-23 T 29-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MC49_RS10390 a6d83d740a234f78cde82c799d5765cb 388 Gene3D G3DSA:3.30.470.20 96 239 1.4E-49 T 29-03-2018 MC49_RS10390 a6d83d740a234f78cde82c799d5765cb 388 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 384 7.9E-178 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MC49_RS10390 a6d83d740a234f78cde82c799d5765cb 388 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 282 - T 29-03-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MC49_RS10390 a6d83d740a234f78cde82c799d5765cb 388 PIRSF PIRSF001554 1 388 1.2E-153 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MC49_RS10390 a6d83d740a234f78cde82c799d5765cb 388 Gene3D G3DSA:3.30.1490.20 21 95 8.1E-25 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MC49_RS14690 0e1cd199a597551368b10a8dafa83ab4 391 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 12 386 4.7E-95 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MC49_RS14690 0e1cd199a597551368b10a8dafa83ab4 391 TIGRFAM TIGR01324 cysta_beta_ly_B: cystathionine beta-lyase 13 388 7.2E-138 T 29-03-2018 IPR006233 Cystathionine beta-lyase, bacterial GO:0004121|GO:0005737|GO:0006520 KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 MC49_RS14690 0e1cd199a597551368b10a8dafa83ab4 391 PIRSF PIRSF001434 1 390 6.4E-109 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MC49_RS14690 0e1cd199a597551368b10a8dafa83ab4 391 Gene3D G3DSA:3.40.640.10 9 257 5.2E-41 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS14690 0e1cd199a597551368b10a8dafa83ab4 391 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 200 214 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MC49_RS14690 0e1cd199a597551368b10a8dafa83ab4 391 SUPERFAMILY SSF53383 47 387 1.55E-87 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS14690 0e1cd199a597551368b10a8dafa83ab4 391 Gene3D G3DSA:3.90.1150.10 258 391 1.7E-31 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS04630 db345a7832bf0c84bd45fb250afcf1b3 651 Gene3D G3DSA:2.30.38.10 429 515 2.4E-10 T 29-03-2018 MC49_RS04630 db345a7832bf0c84bd45fb250afcf1b3 651 Gene3D G3DSA:3.40.50.980 74 266 9.0E-57 T 29-03-2018 MC49_RS04630 db345a7832bf0c84bd45fb250afcf1b3 651 Gene3D G3DSA:3.30.300.30 518 650 1.8E-27 T 29-03-2018 MC49_RS04630 db345a7832bf0c84bd45fb250afcf1b3 651 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 2 645 52.066 T 29-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 MC49_RS04630 db345a7832bf0c84bd45fb250afcf1b3 651 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 24 81 5.8E-18 T 29-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 MC49_RS04630 db345a7832bf0c84bd45fb250afcf1b3 651 Gene3D G3DSA:3.40.50.980 267 428 1.1E-32 T 29-03-2018 MC49_RS04630 db345a7832bf0c84bd45fb250afcf1b3 651 Pfam PF13193 AMP-binding enzyme C-terminal domain 531 609 2.2E-26 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MC49_RS04630 db345a7832bf0c84bd45fb250afcf1b3 651 SUPERFAMILY SSF56801 11 643 4.58E-183 T 29-03-2018 MC49_RS04630 db345a7832bf0c84bd45fb250afcf1b3 651 Pfam PF00501 AMP-binding enzyme 83 522 1.5E-91 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MC49_RS04630 db345a7832bf0c84bd45fb250afcf1b3 651 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 20 643 4.3E-304 T 29-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 MC49_RS04630 db345a7832bf0c84bd45fb250afcf1b3 651 ProSitePatterns PS00455 Putative AMP-binding domain signature. 261 272 - T 29-03-2018 IPR020845 AMP-binding, conserved site MC49_RS00845 243594476cfbd54ddab6cec3906e75c0 622 Pfam PF02780 Transketolase, C-terminal domain 495 611 3.7E-28 T 29-03-2018 IPR033248 Transketolase, C-terminal domain MC49_RS00845 243594476cfbd54ddab6cec3906e75c0 622 SMART SM00861 319 484 1.1E-67 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MC49_RS00845 243594476cfbd54ddab6cec3906e75c0 622 ProSitePatterns PS00802 Transketolase signature 2. 425 441 - T 29-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MC49_RS00845 243594476cfbd54ddab6cec3906e75c0 622 ProSitePatterns PS00801 Transketolase signature 1. 36 55 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MC49_RS00845 243594476cfbd54ddab6cec3906e75c0 622 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 10 620 46.237 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MC49_RS00845 243594476cfbd54ddab6cec3906e75c0 622 Gene3D G3DSA:3.40.50.920 495 621 1.9E-36 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MC49_RS00845 243594476cfbd54ddab6cec3906e75c0 622 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 12 619 0.0 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MC49_RS00845 243594476cfbd54ddab6cec3906e75c0 622 SUPERFAMILY SSF52518 8 199 1.38E-75 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MC49_RS00845 243594476cfbd54ddab6cec3906e75c0 622 SUPERFAMILY SSF52518 243 381 1.38E-75 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MC49_RS00845 243594476cfbd54ddab6cec3906e75c0 622 Pfam PF02779 Transketolase, pyrimidine binding domain 318 479 2.5E-40 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MC49_RS00845 243594476cfbd54ddab6cec3906e75c0 622 SUPERFAMILY SSF52922 492 619 1.7E-32 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MC49_RS00845 243594476cfbd54ddab6cec3906e75c0 622 Gene3D G3DSA:3.40.50.970 3 297 8.0E-76 T 29-03-2018 MC49_RS00845 243594476cfbd54ddab6cec3906e75c0 622 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 12 282 1.8E-117 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MC49_RS00845 243594476cfbd54ddab6cec3906e75c0 622 SUPERFAMILY SSF52518 316 504 1.73E-58 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MC49_RS00845 243594476cfbd54ddab6cec3906e75c0 622 Gene3D G3DSA:3.40.50.970 298 486 6.0E-64 T 29-03-2018 MC49_RS00895 5c523e4408c168b5974257e8de83808b 358 Pfam PF02547 Queuosine biosynthesis protein 4 343 5.9E-131 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 MC49_RS00895 5c523e4408c168b5974257e8de83808b 358 SUPERFAMILY SSF111337 1 343 1.11E-136 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 MC49_RS00895 5c523e4408c168b5974257e8de83808b 358 Gene3D G3DSA:3.40.1780.10 1 129 1.8E-29 T 29-03-2018 MC49_RS00895 5c523e4408c168b5974257e8de83808b 358 Gene3D G3DSA:3.40.1780.10 174 344 2.7E-65 T 29-03-2018 MC49_RS00895 5c523e4408c168b5974257e8de83808b 358 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 344 46.967 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 MC49_RS00895 5c523e4408c168b5974257e8de83808b 358 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 344 1.1E-160 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 MC49_RS09200 e3883fa55c056e5ad9859f7f1589c758 461 Pfam PF00939 Sodium:sulfate symporter transmembrane region 39 460 5.1E-52 T 29-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 MC49_RS09200 e3883fa55c056e5ad9859f7f1589c758 461 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 46 460 1.2E-110 T 29-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 MC49_RS09200 e3883fa55c056e5ad9859f7f1589c758 461 ProSitePatterns PS01271 Sodium:sulfate symporter family signature. 410 426 - T 29-03-2018 IPR031312 Sodium/sulphate symporter, conserved site Reactome: R-HSA-433137 MC49_RS15155 fb52033d2523645db70185ddf8420253 192 PRINTS PR00096 Glutamine amidotransferase superfamily signature 52 61 2.1E-14 T 29-03-2018 MC49_RS15155 fb52033d2523645db70185ddf8420253 192 PRINTS PR00096 Glutamine amidotransferase superfamily signature 79 90 2.1E-14 T 29-03-2018 MC49_RS15155 fb52033d2523645db70185ddf8420253 192 PRINTS PR00096 Glutamine amidotransferase superfamily signature 166 179 2.1E-14 T 29-03-2018 MC49_RS15155 fb52033d2523645db70185ddf8420253 192 Gene3D G3DSA:3.40.50.880 1 192 1.0E-50 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MC49_RS15155 fb52033d2523645db70185ddf8420253 192 SUPERFAMILY SSF52317 3 190 2.06E-48 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MC49_RS15155 fb52033d2523645db70185ddf8420253 192 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 4 187 5.2E-57 T 29-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MC49_RS15155 fb52033d2523645db70185ddf8420253 192 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 79 95 6.7E-6 T 29-03-2018 MC49_RS15155 fb52033d2523645db70185ddf8420253 192 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 49 63 6.7E-6 T 29-03-2018 MC49_RS15155 fb52033d2523645db70185ddf8420253 192 Pfam PF00117 Glutamine amidotransferase class-I 6 187 9.8E-47 T 29-03-2018 IPR017926 Glutamine amidotransferase MC49_RS15155 fb52033d2523645db70185ddf8420253 192 PRINTS PR00097 Anthranilate synthase component II signature 4 18 5.6E-35 T 29-03-2018 MC49_RS15155 fb52033d2523645db70185ddf8420253 192 PRINTS PR00097 Anthranilate synthase component II signature 52 61 5.6E-35 T 29-03-2018 MC49_RS15155 fb52033d2523645db70185ddf8420253 192 PRINTS PR00097 Anthranilate synthase component II signature 104 112 5.6E-35 T 29-03-2018 MC49_RS15155 fb52033d2523645db70185ddf8420253 192 PRINTS PR00097 Anthranilate synthase component II signature 124 136 5.6E-35 T 29-03-2018 MC49_RS15155 fb52033d2523645db70185ddf8420253 192 PRINTS PR00097 Anthranilate synthase component II signature 166 179 5.6E-35 T 29-03-2018 MC49_RS15155 fb52033d2523645db70185ddf8420253 192 PRINTS PR00097 Anthranilate synthase component II signature 79 90 5.6E-35 T 29-03-2018 MC49_RS01935 537a21f447dee0ab0427bb117b2fdabe 244 SUPERFAMILY SSF46548 107 231 2.79E-30 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MC49_RS01935 537a21f447dee0ab0427bb117b2fdabe 244 Gene3D G3DSA:1.10.1060.10 107 243 4.5E-26 T 29-03-2018 MC49_RS01935 537a21f447dee0ab0427bb117b2fdabe 244 SUPERFAMILY SSF54292 3 106 3.85E-28 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MC49_RS01935 537a21f447dee0ab0427bb117b2fdabe 244 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 58 66 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MC49_RS01935 537a21f447dee0ab0427bb117b2fdabe 244 Pfam PF13183 4Fe-4S dicluster domain 146 219 1.2E-11 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MC49_RS01935 537a21f447dee0ab0427bb117b2fdabe 244 Gene3D G3DSA:3.10.20.30 1 106 7.3E-30 T 29-03-2018 IPR012675 Beta-grasp domain MC49_RS01935 537a21f447dee0ab0427bb117b2fdabe 244 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 149 160 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MC49_RS01935 537a21f447dee0ab0427bb117b2fdabe 244 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 9 111 1.7E-31 T 29-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 MC49_RS01935 537a21f447dee0ab0427bb117b2fdabe 244 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 11 229 3.5E-95 T 29-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 MC49_RS08945 0d19a70ba79235bf4430cf7d948c988d 343 PIRSF PIRSF002825 1 340 8.4E-74 T 29-03-2018 IPR026045 Ferric binding protein MC49_RS08945 0d19a70ba79235bf4430cf7d948c988d 343 Gene3D G3DSA:3.40.190.10 25 144 1.1E-12 T 29-03-2018 MC49_RS08945 0d19a70ba79235bf4430cf7d948c988d 343 SUPERFAMILY SSF53850 25 326 6.09E-73 T 29-03-2018 MC49_RS08945 0d19a70ba79235bf4430cf7d948c988d 343 Pfam PF13343 Bacterial extracellular solute-binding protein 75 290 1.4E-31 T 29-03-2018 MC49_RS08945 0d19a70ba79235bf4430cf7d948c988d 343 Gene3D G3DSA:3.40.190.10 145 295 1.4E-35 T 29-03-2018 MC49_RS09305 29829cf44235e98187cde6d63c65fd61 151 Gene3D G3DSA:1.10.3680.10 5 150 1.9E-15 T 29-03-2018 IPR029024 TerB-like MC49_RS09305 29829cf44235e98187cde6d63c65fd61 151 Pfam PF05099 Tellurite resistance protein TerB 15 149 1.3E-24 T 29-03-2018 IPR007791 Co-chaperone DjlA, N-terminal MC49_RS09305 29829cf44235e98187cde6d63c65fd61 151 SUPERFAMILY SSF158682 21 150 1.44E-18 T 29-03-2018 MC49_RS08085 d54dafba13a75a63d3171b08f187dd57 150 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 7 148 37.125 T 29-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MC49_RS08085 d54dafba13a75a63d3171b08f187dd57 150 Pfam PF07977 FabA-like domain 16 140 2.2E-39 T 29-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MC49_RS08085 d54dafba13a75a63d3171b08f187dd57 150 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 7 145 3.0E-60 T 29-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MC49_RS08085 d54dafba13a75a63d3171b08f187dd57 150 SUPERFAMILY SSF54637 9 148 5.87E-50 T 29-03-2018 IPR029069 HotDog domain MC49_RS08085 d54dafba13a75a63d3171b08f187dd57 150 Gene3D G3DSA:3.10.129.10 1 148 3.7E-55 T 29-03-2018 MC49_RS12625 68cbc415d243a549aa1a8834e8864ae1 454 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 12 451 2.9E-186 T 29-03-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MC49_RS12625 68cbc415d243a549aa1a8834e8864ae1 454 SUPERFAMILY SSF52540 108 376 1.93E-95 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS12625 68cbc415d243a549aa1a8834e8864ae1 454 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 161 371 1.3E-71 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MC49_RS12625 68cbc415d243a549aa1a8834e8864ae1 454 Gene3D G3DSA:3.40.50.300 82 371 6.9E-83 T 29-03-2018 MC49_RS12625 68cbc415d243a549aa1a8834e8864ae1 454 SMART SM00382 173 355 2.5E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS12625 68cbc415d243a549aa1a8834e8864ae1 454 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 362 371 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MC49_RS12625 68cbc415d243a549aa1a8834e8864ae1 454 TIGRFAM TIGR03496 FliI_clade1: flagellar protein export ATPase FliI 29 450 1.4E-195 T 29-03-2018 IPR020005 Flagellar export ATPase FliI, clade 1 GO:0016887|GO:0044780|GO:0071973 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MC49_RS02725 ca63849c98ba3fc3f82c9e44ef085ada 285 Gene3D G3DSA:2.30.330.10 207 284 1.6E-14 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) MC49_RS02725 ca63849c98ba3fc3f82c9e44ef085ada 285 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 214 280 4.8E-14 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) MC49_RS02725 ca63849c98ba3fc3f82c9e44ef085ada 285 SUPERFAMILY SSF101801 213 284 3.01E-13 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) MC49_RS05300 9cc24cc3487fe6238c4edb5bf12894e5 493 PIRSF PIRSF006060 12 484 1.7E-51 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MC49_RS05300 9cc24cc3487fe6238c4edb5bf12894e5 493 Pfam PF13520 Amino acid permease 21 454 2.9E-60 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MC49_RS05300 9cc24cc3487fe6238c4edb5bf12894e5 493 TIGRFAM TIGR03813 put_Glu_GABA_T: putative glutamate/gamma-aminobutyrate antiporter 15 487 3.2E-253 T 29-03-2018 IPR022520 Putative glutamate/gamma-aminobutyrate antiporter MC49_RS14445 811f4f5060200a6d07b8eebcf0f72ce3 218 SUPERFAMILY SSF46785 160 216 1.58E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS14445 811f4f5060200a6d07b8eebcf0f72ce3 218 SUPERFAMILY SSF51206 32 144 4.98E-26 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like MC49_RS14445 811f4f5060200a6d07b8eebcf0f72ce3 218 Gene3D G3DSA:2.60.120.10 24 130 2.1E-19 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MC49_RS14445 811f4f5060200a6d07b8eebcf0f72ce3 218 ProSitePatterns PS00888 Cyclic nucleotide-binding domain signature 1. 49 65 - T 29-03-2018 IPR018488 Cyclic nucleotide-binding, conserved site MC49_RS14445 811f4f5060200a6d07b8eebcf0f72ce3 218 Gene3D G3DSA:1.10.10.10 131 218 5.3E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS14445 811f4f5060200a6d07b8eebcf0f72ce3 218 Pfam PF00027 Cyclic nucleotide-binding domain 43 128 2.2E-18 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain MC49_RS14445 811f4f5060200a6d07b8eebcf0f72ce3 218 SMART SM00100 18 140 2.0E-11 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain MC49_RS16885 e33651ee81c1975894100d2589c2817d 237 SUPERFAMILY SSF53850 2 234 1.09E-28 T 29-03-2018 MC49_RS16885 e33651ee81c1975894100d2589c2817d 237 Gene3D G3DSA:3.40.190.10 99 237 1.3E-5 T 29-03-2018 MC49_RS16885 e33651ee81c1975894100d2589c2817d 237 Gene3D G3DSA:3.40.190.10 1 98 4.4E-7 T 29-03-2018 MC49_RS16885 e33651ee81c1975894100d2589c2817d 237 Pfam PF13531 Bacterial extracellular solute-binding protein 2 233 1.6E-30 T 29-03-2018 MC49_RS05825 7626d53de402f271609e1d1ee795a25e 360 Gene3D G3DSA:3.20.20.190 27 354 1.5E-59 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 MC49_RS05825 7626d53de402f271609e1d1ee795a25e 360 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 34 348 6.1E-65 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 MC49_RS05825 7626d53de402f271609e1d1ee795a25e 360 SUPERFAMILY SSF51695 29 353 1.05E-87 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 MC49_RS04040 96781a29d47583ea6150ad379e7b3300 206 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 206 4.1E-87 T 29-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 MC49_RS04040 96781a29d47583ea6150ad379e7b3300 206 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 95 2.8E-32 T 29-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 MC49_RS04040 96781a29d47583ea6150ad379e7b3300 206 SMART SM00363 96 160 5.8E-21 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MC49_RS04040 96781a29d47583ea6150ad379e7b3300 206 SUPERFAMILY SSF55174 3 206 2.09E-73 T 29-03-2018 MC49_RS04040 96781a29d47583ea6150ad379e7b3300 206 Pfam PF01479 S4 domain 97 143 6.0E-19 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MC49_RS04040 96781a29d47583ea6150ad379e7b3300 206 Gene3D G3DSA:3.10.290.10 102 144 1.3E-15 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MC49_RS04040 96781a29d47583ea6150ad379e7b3300 206 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 206 36.349 T 29-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 MC49_RS04040 96781a29d47583ea6150ad379e7b3300 206 ProSitePatterns PS00632 Ribosomal protein S4 signature. 94 118 - T 29-03-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04040 96781a29d47583ea6150ad379e7b3300 206 SMART SM01390 3 95 1.9E-49 T 29-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 MC49_RS04040 96781a29d47583ea6150ad379e7b3300 206 Gene3D G3DSA:1.10.1050.10 145 206 1.7E-19 T 29-03-2018 MC49_RS04040 96781a29d47583ea6150ad379e7b3300 206 Gene3D G3DSA:1.10.1050.10 1 101 1.4E-41 T 29-03-2018 MC49_RS00330 9195c38a027f58e7aac9cfc79ddfd79c 66 SMART SM00530 7 61 7.2E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS00330 9195c38a027f58e7aac9cfc79ddfd79c 66 SUPERFAMILY SSF47413 4 62 1.54E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS00330 9195c38a027f58e7aac9cfc79ddfd79c 66 Gene3D G3DSA:1.10.260.40 1 66 1.9E-15 T 29-03-2018 MC49_RS00330 9195c38a027f58e7aac9cfc79ddfd79c 66 Pfam PF01381 Helix-turn-helix 8 61 1.7E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS09660 0345583017211158ded2d9a95f96987d 308 Gene3D G3DSA:3.40.190.10 178 262 1.6E-24 T 29-03-2018 MC49_RS09660 0345583017211158ded2d9a95f96987d 308 Gene3D G3DSA:1.10.10.10 3 84 3.5E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS09660 0345583017211158ded2d9a95f96987d 308 Pfam PF03466 LysR substrate binding domain 89 291 9.8E-39 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS09660 0345583017211158ded2d9a95f96987d 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 4.8E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS09660 0345583017211158ded2d9a95f96987d 308 SUPERFAMILY SSF46785 5 111 2.8E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS09660 0345583017211158ded2d9a95f96987d 308 SUPERFAMILY SSF53850 90 294 2.9E-43 T 29-03-2018 MC49_RS09660 0345583017211158ded2d9a95f96987d 308 Gene3D G3DSA:3.40.190.10 89 177 9.3E-13 T 29-03-2018 MC49_RS03380 f8fff9963e5c63a760fbf073677bf940 503 SUPERFAMILY SSF54814 201 278 2.68E-29 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 MC49_RS03380 f8fff9963e5c63a760fbf073677bf940 503 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 4 348 2.8E-125 T 29-03-2018 IPR010213 Transcription termination factor NusA GO:0003723 MC49_RS03380 f8fff9963e5c63a760fbf073677bf940 503 Pfam PF14520 Helix-hairpin-helix domain 377 418 0.0059 T 29-03-2018 MC49_RS03380 f8fff9963e5c63a760fbf073677bf940 503 Pfam PF14520 Helix-hairpin-helix domain 439 493 1.1E-9 T 29-03-2018 MC49_RS03380 f8fff9963e5c63a760fbf073677bf940 503 SUPERFAMILY SSF47794 437 499 2.35E-18 T 29-03-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 MC49_RS03380 f8fff9963e5c63a760fbf073677bf940 503 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 372 421 4.8E-21 T 29-03-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication MC49_RS03380 f8fff9963e5c63a760fbf073677bf940 503 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 447 496 5.1E-19 T 29-03-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication MC49_RS03380 f8fff9963e5c63a760fbf073677bf940 503 SMART SM00316 133 200 3.8E-9 T 29-03-2018 IPR022967 RNA-binding domain, S1 MC49_RS03380 f8fff9963e5c63a760fbf073677bf940 503 Pfam PF08529 NusA N-terminal domain 4 123 1.8E-37 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 MC49_RS03380 f8fff9963e5c63a760fbf073677bf940 503 SUPERFAMILY SSF69705 1 126 1.02E-41 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 MC49_RS03380 f8fff9963e5c63a760fbf073677bf940 503 Gene3D G3DSA:3.30.1480.10 1 128 1.5E-46 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 MC49_RS03380 f8fff9963e5c63a760fbf073677bf940 503 Gene3D G3DSA:1.10.150.20 362 428 2.0E-15 T 29-03-2018 MC49_RS03380 f8fff9963e5c63a760fbf073677bf940 503 Pfam PF13184 NusA-like KH domain 230 297 4.2E-27 T 29-03-2018 IPR025249 KH domain, NusA-like GO:0003723 MC49_RS03380 f8fff9963e5c63a760fbf073677bf940 503 Pfam PF00575 S1 RNA binding domain 133 195 1.3E-4 T 29-03-2018 IPR003029 S1 domain GO:0003676 MC49_RS03380 f8fff9963e5c63a760fbf073677bf940 503 Gene3D G3DSA:2.40.50.140 129 198 1.4E-13 T 29-03-2018 MC49_RS03380 f8fff9963e5c63a760fbf073677bf940 503 SUPERFAMILY SSF47794 363 422 4.24E-16 T 29-03-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 MC49_RS03380 f8fff9963e5c63a760fbf073677bf940 503 Gene3D G3DSA:1.10.150.20 438 497 1.7E-15 T 29-03-2018 MC49_RS03380 f8fff9963e5c63a760fbf073677bf940 503 Gene3D G3DSA:3.30.300.20 199 276 8.2E-33 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta MC49_RS03380 f8fff9963e5c63a760fbf073677bf940 503 Gene3D G3DSA:3.30.300.20 278 361 1.3E-9 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta MC49_RS03380 f8fff9963e5c63a760fbf073677bf940 503 SUPERFAMILY SSF50249 132 199 2.23E-17 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS03380 f8fff9963e5c63a760fbf073677bf940 503 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 417 27.842 T 29-03-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 MC49_RS03380 f8fff9963e5c63a760fbf073677bf940 503 SUPERFAMILY SSF54814 279 334 1.26E-11 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 MC49_RS02175 da29b6f72eee44ac9f84d28610a1ba71 295 Pfam PF12834 Phage integrase, N-terminal 1 91 3.8E-36 T 29-03-2018 IPR024457 Putative integrase, N-terminal MC49_RS02175 da29b6f72eee44ac9f84d28610a1ba71 295 SUPERFAMILY SSF56349 23 270 3.24E-13 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MC49_RS02175 da29b6f72eee44ac9f84d28610a1ba71 295 Pfam PF12835 Integrase 104 251 3.5E-58 T 29-03-2018 IPR024456 Integrase catalytic domain, putative MC49_RS02175 da29b6f72eee44ac9f84d28610a1ba71 295 Gene3D G3DSA:1.10.150.130 3 92 5.5E-5 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal MC49_RS02175 da29b6f72eee44ac9f84d28610a1ba71 295 Gene3D G3DSA:1.10.443.10 111 283 4.4E-12 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MC49_RS18235 d25267dcba1b5e9538548a79f346132f 133 Pfam PF06146 Phosphate-starvation-inducible E 55 120 1.7E-14 T 29-03-2018 IPR020948 Phosphate-starvation-induced PsiE-like MC49_RS18235 d25267dcba1b5e9538548a79f346132f 133 PIRSF PIRSF029598 1 133 3.4E-43 T 29-03-2018 IPR009315 Phosphate-starvation-induced PsiE GO:0016021|GO:0016036 MC49_RS09195 39c516b8e71a7420bd806d5a1d1e0226 432 ProSitePatterns PS00164 Enolase signature. 340 353 - T 29-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS09195 39c516b8e71a7420bd806d5a1d1e0226 432 SMART SM01192 143 431 2.1E-212 T 29-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MC49_RS09195 39c516b8e71a7420bd806d5a1d1e0226 432 SMART SM01193 4 134 9.9E-93 T 29-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MC49_RS09195 39c516b8e71a7420bd806d5a1d1e0226 432 SUPERFAMILY SSF51604 143 428 1.7E-127 T 29-03-2018 IPR029065 Enolase C-terminal domain-like MC49_RS09195 39c516b8e71a7420bd806d5a1d1e0226 432 Pfam PF00113 Enolase, C-terminal TIM barrel domain 144 430 1.8E-140 T 29-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MC49_RS09195 39c516b8e71a7420bd806d5a1d1e0226 432 Pfam PF03952 Enolase, N-terminal domain 4 134 2.0E-57 T 29-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MC49_RS09195 39c516b8e71a7420bd806d5a1d1e0226 432 Gene3D G3DSA:3.20.20.120 128 431 2.6E-103 T 29-03-2018 IPR029065 Enolase C-terminal domain-like MC49_RS09195 39c516b8e71a7420bd806d5a1d1e0226 432 PRINTS PR00148 Enolase signature 165 178 2.5E-44 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MC49_RS09195 39c516b8e71a7420bd806d5a1d1e0226 432 PRINTS PR00148 Enolase signature 317 328 2.5E-44 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MC49_RS09195 39c516b8e71a7420bd806d5a1d1e0226 432 PRINTS PR00148 Enolase signature 37 51 2.5E-44 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MC49_RS09195 39c516b8e71a7420bd806d5a1d1e0226 432 PRINTS PR00148 Enolase signature 107 123 2.5E-44 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MC49_RS09195 39c516b8e71a7420bd806d5a1d1e0226 432 PRINTS PR00148 Enolase signature 340 354 2.5E-44 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MC49_RS09195 39c516b8e71a7420bd806d5a1d1e0226 432 PRINTS PR00148 Enolase signature 369 386 2.5E-44 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MC49_RS09195 39c516b8e71a7420bd806d5a1d1e0226 432 Hamap MF_00318 Enolase [eno]. 2 417 43.966 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MC49_RS09195 39c516b8e71a7420bd806d5a1d1e0226 432 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 429 4.9E-208 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MC49_RS09195 39c516b8e71a7420bd806d5a1d1e0226 432 SUPERFAMILY SSF54826 3 138 7.73E-56 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MC49_RS09195 39c516b8e71a7420bd806d5a1d1e0226 432 PIRSF PIRSF001400 1 431 1.1E-192 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MC49_RS09195 39c516b8e71a7420bd806d5a1d1e0226 432 Gene3D G3DSA:3.30.390.10 3 127 2.5E-51 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MC49_RS12565 abafda1deb5e00e860eb6c410dc5a26f 315 Gene3D G3DSA:1.20.1330.10 42 280 2.5E-17 T 29-03-2018 MC49_RS12565 abafda1deb5e00e860eb6c410dc5a26f 315 Pfam PF00669 Bacterial flagellin N-terminal helical region 4 140 1.1E-19 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 MC49_RS12565 abafda1deb5e00e860eb6c410dc5a26f 315 SUPERFAMILY SSF64518 1 314 3.79E-45 T 29-03-2018 MC49_RS12565 abafda1deb5e00e860eb6c410dc5a26f 315 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 2 197 3.6E-56 T 29-03-2018 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 MC49_RS18385 b5782c3de71ca1a540a09eb44bfe80ba 505 Pfam PF00152 tRNA synthetases class II (D, K and N) 162 501 2.4E-81 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS18385 b5782c3de71ca1a540a09eb44bfe80ba 505 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 13 503 2.6E-228 T 29-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MC49_RS18385 b5782c3de71ca1a540a09eb44bfe80ba 505 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 20 505 45.136 T 29-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MC49_RS18385 b5782c3de71ca1a540a09eb44bfe80ba 505 PIRSF PIRSF039101 1 505 2.4E-200 T 29-03-2018 IPR034762 Bacterial/eukaryotic lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MC49_RS18385 b5782c3de71ca1a540a09eb44bfe80ba 505 Gene3D G3DSA:2.40.50.140 14 154 2.3E-39 T 29-03-2018 MC49_RS18385 b5782c3de71ca1a540a09eb44bfe80ba 505 SUPERFAMILY SSF50249 13 155 2.06E-44 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS18385 b5782c3de71ca1a540a09eb44bfe80ba 505 PRINTS PR00982 Lysyl-tRNA synthetase signature 386 402 1.5E-39 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MC49_RS18385 b5782c3de71ca1a540a09eb44bfe80ba 505 PRINTS PR00982 Lysyl-tRNA synthetase signature 215 231 1.5E-39 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MC49_RS18385 b5782c3de71ca1a540a09eb44bfe80ba 505 PRINTS PR00982 Lysyl-tRNA synthetase signature 199 209 1.5E-39 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MC49_RS18385 b5782c3de71ca1a540a09eb44bfe80ba 505 PRINTS PR00982 Lysyl-tRNA synthetase signature 262 279 1.5E-39 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MC49_RS18385 b5782c3de71ca1a540a09eb44bfe80ba 505 PRINTS PR00982 Lysyl-tRNA synthetase signature 244 257 1.5E-39 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MC49_RS18385 b5782c3de71ca1a540a09eb44bfe80ba 505 Pfam PF01336 OB-fold nucleic acid binding domain 68 146 1.4E-14 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 MC49_RS18385 b5782c3de71ca1a540a09eb44bfe80ba 505 Gene3D G3DSA:3.30.930.10 156 501 3.4E-104 T 29-03-2018 MC49_RS18385 b5782c3de71ca1a540a09eb44bfe80ba 505 SUPERFAMILY SSF55681 162 502 2.4E-123 T 29-03-2018 MC49_RS04425 76b9bb2c5f30cae426aa025cd4729c97 252 Pfam PF00455 DeoR C terminal sensor domain 76 232 5.4E-54 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain MC49_RS04425 76b9bb2c5f30cae426aa025cd4729c97 252 SUPERFAMILY SSF100950 74 233 1.1E-29 T 29-03-2018 MC49_RS04425 76b9bb2c5f30cae426aa025cd4729c97 252 Gene3D G3DSA:1.10.10.10 1 63 1.5E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS04425 76b9bb2c5f30cae426aa025cd4729c97 252 SUPERFAMILY SSF46785 3 73 1.29E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS04425 76b9bb2c5f30cae426aa025cd4729c97 252 Gene3D G3DSA:3.40.50.1360 73 239 2.9E-41 T 29-03-2018 MC49_RS04425 76b9bb2c5f30cae426aa025cd4729c97 252 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 MC49_RS04425 76b9bb2c5f30cae426aa025cd4729c97 252 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 7.9E-13 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MC49_RS04425 76b9bb2c5f30cae426aa025cd4729c97 252 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 7.9E-13 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MC49_RS04425 76b9bb2c5f30cae426aa025cd4729c97 252 Pfam PF08220 DeoR-like helix-turn-helix domain 6 61 3.5E-25 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MC49_RS04425 76b9bb2c5f30cae426aa025cd4729c97 252 SMART SM01134 72 233 2.2E-72 T 29-03-2018 MC49_RS04425 76b9bb2c5f30cae426aa025cd4729c97 252 SMART SM00420 6 58 5.8E-28 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MC49_RS06675 2e60a9a2df936eda9daa11625b2806e1 393 SUPERFAMILY SSF103473 4 388 2.49E-61 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS06675 2e60a9a2df936eda9daa11625b2806e1 393 ProSitePatterns PS00216 Sugar transport proteins signature 1. 58 74 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MC49_RS06675 2e60a9a2df936eda9daa11625b2806e1 393 Gene3D G3DSA:1.20.1250.20 194 391 2.4E-16 T 29-03-2018 MC49_RS06675 2e60a9a2df936eda9daa11625b2806e1 393 Gene3D G3DSA:1.20.1250.20 1 193 3.9E-36 T 29-03-2018 MC49_RS06675 2e60a9a2df936eda9daa11625b2806e1 393 PRINTS PR01035 Tetracycline resistance protein signature 14 30 7.4E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MC49_RS06675 2e60a9a2df936eda9daa11625b2806e1 393 PRINTS PR01035 Tetracycline resistance protein signature 302 322 7.4E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MC49_RS06675 2e60a9a2df936eda9daa11625b2806e1 393 PRINTS PR01035 Tetracycline resistance protein signature 129 151 7.4E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MC49_RS06675 2e60a9a2df936eda9daa11625b2806e1 393 Pfam PF07690 Major Facilitator Superfamily 9 352 1.0E-46 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS06675 2e60a9a2df936eda9daa11625b2806e1 393 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 4 377 1.0E-72 T 29-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 MC49_RS03125 af5cca19301b99a6c4819fa063b23684 950 SUPERFAMILY SSF51126 54 624 1.05E-21 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor MC49_RS03125 af5cca19301b99a6c4819fa063b23684 950 Gene3D G3DSA:2.40.128.130 652 950 4.1E-47 T 29-03-2018 MC49_RS03125 af5cca19301b99a6c4819fa063b23684 950 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 522 950 7.3E-102 T 29-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 MC49_RS03125 af5cca19301b99a6c4819fa063b23684 950 Pfam PF03212 Pertactin 503 623 1.0E-26 T 29-03-2018 IPR004899 Pertactin, central region MC49_RS03125 af5cca19301b99a6c4819fa063b23684 950 SMART SM00869 686 940 1.1E-41 T 29-03-2018 IPR005546 Autotransporter beta-domain MC49_RS03125 af5cca19301b99a6c4819fa063b23684 950 Pfam PF03797 Autotransporter beta-domain 689 930 1.5E-49 T 29-03-2018 IPR005546 Autotransporter beta-domain MC49_RS03125 af5cca19301b99a6c4819fa063b23684 950 Gene3D G3DSA:2.160.20.20 98 630 4.7E-45 T 29-03-2018 IPR012332 P22 tailspike C-terminal domain-like MC49_RS03125 af5cca19301b99a6c4819fa063b23684 950 SUPERFAMILY SSF103515 671 950 1.7E-45 T 29-03-2018 IPR005546 Autotransporter beta-domain MC49_RS03125 af5cca19301b99a6c4819fa063b23684 950 PRINTS PR01484 Pertactin virulence factor family signature 666 684 2.9E-12 T 29-03-2018 IPR003991 Pertactin virulence factor family GO:0007155 MC49_RS03125 af5cca19301b99a6c4819fa063b23684 950 PRINTS PR01484 Pertactin virulence factor family signature 906 931 2.9E-12 T 29-03-2018 IPR003991 Pertactin virulence factor family GO:0007155 MC49_RS03125 af5cca19301b99a6c4819fa063b23684 950 PRINTS PR01484 Pertactin virulence factor family signature 868 889 2.9E-12 T 29-03-2018 IPR003991 Pertactin virulence factor family GO:0007155 MC49_RS03125 af5cca19301b99a6c4819fa063b23684 950 PRINTS PR01484 Pertactin virulence factor family signature 821 838 2.9E-12 T 29-03-2018 IPR003991 Pertactin virulence factor family GO:0007155 MC49_RS03125 af5cca19301b99a6c4819fa063b23684 950 PRINTS PR01484 Pertactin virulence factor family signature 727 751 2.9E-12 T 29-03-2018 IPR003991 Pertactin virulence factor family GO:0007155 MC49_RS12760 5e48b022a613226e825ba2a84a3c57b0 588 Hamap MF_01518 Adenine deaminase [ade]. 31 583 34.096 T 29-03-2018 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 MC49_RS12760 5e48b022a613226e825ba2a84a3c57b0 588 SUPERFAMILY SSF51556 85 333 3.06E-23 T 29-03-2018 IPR032466 Metal-dependent hydrolase MC49_RS12760 5e48b022a613226e825ba2a84a3c57b0 588 SUPERFAMILY SSF51338 333 364 2.36E-15 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS12760 5e48b022a613226e825ba2a84a3c57b0 588 SUPERFAMILY SSF51338 19 85 2.36E-15 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS12760 5e48b022a613226e825ba2a84a3c57b0 588 Pfam PF01979 Amidohydrolase family 81 364 8.2E-28 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MC49_RS12760 5e48b022a613226e825ba2a84a3c57b0 588 Gene3D G3DSA:3.20.20.140 90 268 9.0E-9 T 29-03-2018 MC49_RS12760 5e48b022a613226e825ba2a84a3c57b0 588 Pfam PF13382 Adenine deaminase C-terminal domain 435 579 1.4E-56 T 29-03-2018 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 MC49_RS12760 5e48b022a613226e825ba2a84a3c57b0 588 Gene3D G3DSA:2.30.40.10 28 89 1.7E-14 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS12760 5e48b022a613226e825ba2a84a3c57b0 588 Gene3D G3DSA:2.30.40.10 272 372 6.7E-12 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS12760 5e48b022a613226e825ba2a84a3c57b0 588 TIGRFAM TIGR01178 ade: adenine deaminase 31 582 9.7E-201 T 29-03-2018 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 MC49_RS14970 356758b317e9faed3e811384f9373e2f 299 Gene3D G3DSA:3.40.190.10 178 271 7.4E-20 T 29-03-2018 MC49_RS14970 356758b317e9faed3e811384f9373e2f 299 Pfam PF03466 LysR substrate binding domain 89 295 3.0E-39 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS14970 356758b317e9faed3e811384f9373e2f 299 Gene3D G3DSA:1.10.10.10 1 84 2.3E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS14970 356758b317e9faed3e811384f9373e2f 299 Gene3D G3DSA:3.40.190.10 89 177 3.7E-14 T 29-03-2018 MC49_RS14970 356758b317e9faed3e811384f9373e2f 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 6.8E-22 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS14970 356758b317e9faed3e811384f9373e2f 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 4.8E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS14970 356758b317e9faed3e811384f9373e2f 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 4.8E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS14970 356758b317e9faed3e811384f9373e2f 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 4.8E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS14970 356758b317e9faed3e811384f9373e2f 299 SUPERFAMILY SSF53850 92 296 8.54E-36 T 29-03-2018 MC49_RS14970 356758b317e9faed3e811384f9373e2f 299 SUPERFAMILY SSF46785 3 87 1.16E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS06350 9440033f7cd73f8fb8e630602640c695 256 SUPERFAMILY SSF54534 45 252 3.06E-61 T 29-03-2018 MC49_RS06350 9440033f7cd73f8fb8e630602640c695 256 Pfam PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 36 154 7.4E-33 T 29-03-2018 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 MC49_RS06350 9440033f7cd73f8fb8e630602640c695 256 Gene3D G3DSA:3.10.50.40 137 253 4.6E-43 T 29-03-2018 MC49_RS06350 9440033f7cd73f8fb8e630602640c695 256 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 163 249 5.2E-30 T 29-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain MC49_RS06350 9440033f7cd73f8fb8e630602640c695 256 Gene3D G3DSA:1.10.287.460 16 136 1.4E-25 T 29-03-2018 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 MC49_RS09670 9bbae31644d254d1a91db951192eac03 416 SUPERFAMILY SSF50621 245 414 2.93E-54 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MC49_RS09670 9bbae31644d254d1a91db951192eac03 416 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 48 271 4.0E-55 T 29-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 MC49_RS09670 9bbae31644d254d1a91db951192eac03 416 PRINTS PR01181 Diaminopimelate decarboxylase signature 153 162 2.9E-26 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MC49_RS09670 9bbae31644d254d1a91db951192eac03 416 PRINTS PR01181 Diaminopimelate decarboxylase signature 69 86 2.9E-26 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MC49_RS09670 9bbae31644d254d1a91db951192eac03 416 PRINTS PR01181 Diaminopimelate decarboxylase signature 289 307 2.9E-26 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MC49_RS09670 9bbae31644d254d1a91db951192eac03 416 PRINTS PR01181 Diaminopimelate decarboxylase signature 381 403 2.9E-26 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MC49_RS09670 9bbae31644d254d1a91db951192eac03 416 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 16 413 9.8E-124 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MC49_RS09670 9bbae31644d254d1a91db951192eac03 416 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 51 69 - T 29-03-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site MC49_RS09670 9bbae31644d254d1a91db951192eac03 416 SUPERFAMILY SSF51419 25 273 1.83E-59 T 29-03-2018 IPR029066 PLP-binding barrel MC49_RS09670 9bbae31644d254d1a91db951192eac03 416 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 202 371 7.1E-22 T 29-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 MC49_RS09670 9bbae31644d254d1a91db951192eac03 416 Gene3D G3DSA:3.20.20.10 39 260 3.9E-47 T 29-03-2018 IPR029066 PLP-binding barrel MC49_RS09670 9bbae31644d254d1a91db951192eac03 416 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 14 414 38.1 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MC49_RS09670 9bbae31644d254d1a91db951192eac03 416 Gene3D G3DSA:2.40.37.10 261 416 2.2E-44 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MC49_RS09670 9bbae31644d254d1a91db951192eac03 416 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 51 69 6.2E-21 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MC49_RS09670 9bbae31644d254d1a91db951192eac03 416 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 261 280 6.2E-21 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MC49_RS09670 9bbae31644d254d1a91db951192eac03 416 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 71 83 6.2E-21 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MC49_RS09670 9bbae31644d254d1a91db951192eac03 416 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 371 384 6.2E-21 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MC49_RS09670 9bbae31644d254d1a91db951192eac03 416 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 178 191 6.2E-21 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MC49_RS06550 2b87746f6d70744c7a4c3cb0972c7366 427 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 290 297 - T 29-03-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MC49_RS06550 2b87746f6d70744c7a4c3cb0972c7366 427 SUPERFAMILY SSF52440 1 103 1.73E-36 T 29-03-2018 IPR016185 Pre-ATP-grasp domain MC49_RS06550 2b87746f6d70744c7a4c3cb0972c7366 427 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 103 296 3.3E-83 T 29-03-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MC49_RS06550 2b87746f6d70744c7a4c3cb0972c7366 427 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 422 1.5E-181 T 29-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MC49_RS06550 2b87746f6d70744c7a4c3cb0972c7366 427 Gene3D G3DSA:3.30.470.20 191 329 9.4E-61 T 29-03-2018 MC49_RS06550 2b87746f6d70744c7a4c3cb0972c7366 427 Gene3D G3DSA:3.90.600.10 330 423 3.9E-35 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MC49_RS06550 2b87746f6d70744c7a4c3cb0972c7366 427 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 422 43.098 T 29-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MC49_RS06550 2b87746f6d70744c7a4c3cb0972c7366 427 SMART SM01210 330 422 4.9E-55 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MC49_RS06550 2b87746f6d70744c7a4c3cb0972c7366 427 Gene3D G3DSA:3.30.1490.20 134 189 3.8E-23 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MC49_RS06550 2b87746f6d70744c7a4c3cb0972c7366 427 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 102 2.3E-34 T 29-03-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MC49_RS06550 2b87746f6d70744c7a4c3cb0972c7366 427 Gene3D G3DSA:3.40.50.20 2 95 1.8E-37 T 29-03-2018 MC49_RS06550 2b87746f6d70744c7a4c3cb0972c7366 427 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 331 420 4.3E-31 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MC49_RS06550 2b87746f6d70744c7a4c3cb0972c7366 427 SMART SM01209 103 296 4.1E-140 T 29-03-2018 MC49_RS06550 2b87746f6d70744c7a4c3cb0972c7366 427 SUPERFAMILY SSF56059 104 323 3.89E-68 T 29-03-2018 MC49_RS06550 2b87746f6d70744c7a4c3cb0972c7366 427 SUPERFAMILY SSF51246 329 423 9.42E-33 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MC49_RS14920 4d7b51cd8e0b71292787e22df1907e3d 294 Pfam PF13714 Phosphoenolpyruvate phosphomutase 15 252 5.4E-49 T 29-03-2018 MC49_RS14920 4d7b51cd8e0b71292787e22df1907e3d 294 SUPERFAMILY SSF51621 7 290 1.57E-98 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MC49_RS14920 4d7b51cd8e0b71292787e22df1907e3d 294 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 7 291 7.5E-133 T 29-03-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 MC49_RS14920 4d7b51cd8e0b71292787e22df1907e3d 294 Gene3D G3DSA:3.20.20.60 2 294 3.7E-89 T 29-03-2018 MC49_RS14920 4d7b51cd8e0b71292787e22df1907e3d 294 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 4 292 50.028 T 29-03-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 MC49_RS14920 4d7b51cd8e0b71292787e22df1907e3d 294 ProSitePatterns PS00161 Isocitrate lyase signature. 121 126 - T 29-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 MC49_RS11570 8668d30c8bfe74e76cee2cab1bf78cd9 143 Gene3D G3DSA:1.20.1290.10 3 143 2.4E-36 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MC49_RS11570 8668d30c8bfe74e76cee2cab1bf78cd9 143 SUPERFAMILY SSF69118 8 142 2.44E-44 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MC49_RS11570 8668d30c8bfe74e76cee2cab1bf78cd9 143 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 29 77 7.2E-17 T 29-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MC49_RS11570 8668d30c8bfe74e76cee2cab1bf78cd9 143 Pfam PF02627 Carboxymuconolactone decarboxylase family 16 95 5.8E-20 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MC49_RS14670 119e8f7d97434e75bed78aa3a7c36066 195 SUPERFAMILY SSF55811 14 191 1.82E-38 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MC49_RS14670 119e8f7d97434e75bed78aa3a7c36066 195 TIGRFAM TIGR00052 TIGR00052: nudix-type nucleoside diphosphatase, YffH/AdpP family 10 189 6.3E-45 T 29-03-2018 IPR004385 Nucleoside diphosphate pyrophosphatase GO:0016818|GO:0046872 Reactome: R-HSA-480985 MC49_RS14670 119e8f7d97434e75bed78aa3a7c36066 195 Gene3D G3DSA:3.90.79.10 1 194 1.6E-28 T 29-03-2018 MC49_RS16650 a3f671acdde9b3f93185f2176c72e103 258 Pfam PF02311 AraC-like ligand binding domain 19 97 2.5E-11 T 29-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 MC49_RS16650 a3f671acdde9b3f93185f2176c72e103 258 Gene3D G3DSA:2.60.120.10 17 131 2.5E-12 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MC49_RS16650 a3f671acdde9b3f93185f2176c72e103 258 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 239 255 2.5E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MC49_RS16650 a3f671acdde9b3f93185f2176c72e103 258 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 224 239 2.5E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MC49_RS16650 a3f671acdde9b3f93185f2176c72e103 258 Gene3D G3DSA:1.10.10.60 153 206 5.7E-9 T 29-03-2018 MC49_RS16650 a3f671acdde9b3f93185f2176c72e103 258 Gene3D G3DSA:1.10.10.60 207 257 5.7E-10 T 29-03-2018 MC49_RS16650 a3f671acdde9b3f93185f2176c72e103 258 Pfam PF12833 Helix-turn-helix domain 179 256 7.2E-22 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MC49_RS16650 a3f671acdde9b3f93185f2176c72e103 258 SMART SM00342 173 255 2.2E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MC49_RS16650 a3f671acdde9b3f93185f2176c72e103 258 SUPERFAMILY SSF51182 29 188 4.45E-17 T 29-03-2018 IPR011051 RmlC-like cupin domain MC49_RS16650 a3f671acdde9b3f93185f2176c72e103 258 SUPERFAMILY SSF46689 209 257 3.45E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS16650 a3f671acdde9b3f93185f2176c72e103 258 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 208 251 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MC49_RS02105 19cbf56a02d8218afedc1b02f065f025 456 Gene3D G3DSA:1.10.40.30 362 439 1.4E-14 T 29-03-2018 MC49_RS02105 19cbf56a02d8218afedc1b02f065f025 456 Pfam PF10397 Adenylosuccinate lyase C-terminus 363 438 1.9E-11 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MC49_RS02105 19cbf56a02d8218afedc1b02f065f025 456 Gene3D G3DSA:1.10.275.10 3 103 5.7E-14 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal MC49_RS02105 19cbf56a02d8218afedc1b02f065f025 456 PRINTS PR00149 Fumarate lyase superfamily signature 274 290 5.3E-10 T 29-03-2018 IPR000362 Fumarate lyase family MC49_RS02105 19cbf56a02d8218afedc1b02f065f025 456 PRINTS PR00149 Fumarate lyase superfamily signature 144 162 5.3E-10 T 29-03-2018 IPR000362 Fumarate lyase family MC49_RS02105 19cbf56a02d8218afedc1b02f065f025 456 SMART SM00998 362 441 4.9E-15 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MC49_RS02105 19cbf56a02d8218afedc1b02f065f025 456 Pfam PF00206 Lyase 22 285 1.1E-28 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal MC49_RS02105 19cbf56a02d8218afedc1b02f065f025 456 SUPERFAMILY SSF48557 17 438 1.1E-81 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 MC49_RS02105 19cbf56a02d8218afedc1b02f065f025 456 Gene3D G3DSA:1.20.200.10 104 361 3.9E-48 T 29-03-2018 MC49_RS02105 19cbf56a02d8218afedc1b02f065f025 456 PRINTS PR00145 Argininosuccinate lyase family signature 139 159 5.7E-7 T 29-03-2018 MC49_RS02105 19cbf56a02d8218afedc1b02f065f025 456 PRINTS PR00145 Argininosuccinate lyase family signature 229 253 5.7E-7 T 29-03-2018 MC49_RS02105 19cbf56a02d8218afedc1b02f065f025 456 PRINTS PR00145 Argininosuccinate lyase family signature 274 290 5.7E-7 T 29-03-2018 MC49_RS02105 19cbf56a02d8218afedc1b02f065f025 456 ProSitePatterns PS00163 Fumarate lyases signature. 274 283 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 MC49_RS12035 f33bb3e86927b2e06326f7bb344111de 561 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS12035 f33bb3e86927b2e06326f7bb344111de 561 Gene3D G3DSA:1.20.1560.10 14 360 6.3E-33 T 29-03-2018 MC49_RS12035 f33bb3e86927b2e06326f7bb344111de 561 Gene3D G3DSA:3.40.50.300 361 556 6.8E-31 T 29-03-2018 MC49_RS12035 f33bb3e86927b2e06326f7bb344111de 561 SMART SM00382 394 558 0.0013 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS12035 f33bb3e86927b2e06326f7bb344111de 561 SUPERFAMILY SSF90123 33 352 8.63E-16 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MC49_RS12035 f33bb3e86927b2e06326f7bb344111de 561 SUPERFAMILY SSF52540 376 552 1.0E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS12035 f33bb3e86927b2e06326f7bb344111de 561 Pfam PF00005 ABC transporter 399 519 5.9E-16 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS12035 f33bb3e86927b2e06326f7bb344111de 561 Pfam PF06472 ABC transporter transmembrane region 2 14 305 3.9E-64 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MC49_RS10040 dcade5248d070e46a62f56f42626f043 320 SUPERFAMILY SSF47240 7 320 3.02E-105 T 29-03-2018 IPR009078 Ferritin-like superfamily MC49_RS10040 dcade5248d070e46a62f56f42626f043 320 Pfam PF00268 Ribonucleotide reductase, small chain 10 275 1.7E-86 T 29-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MC49_RS10040 dcade5248d070e46a62f56f42626f043 320 PIRSF PIRSF000355 1 317 3.0E-81 T 29-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MC49_RS10040 dcade5248d070e46a62f56f42626f043 320 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 8 320 1.5E-144 T 29-03-2018 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MC49_RS10040 dcade5248d070e46a62f56f42626f043 320 Gene3D G3DSA:1.10.620.20 1 293 7.4E-77 T 29-03-2018 MC49_RS10040 dcade5248d070e46a62f56f42626f043 320 ProSitePatterns PS00368 Ribonucleotide reductase small subunit signature. 98 114 - T 29-03-2018 IPR030475 Ribonucleotide reductase small subunit, acitve site KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MC49_RS05380 d2842a99efbca70b7a9e0454c6026128 265 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 186 259 5.6E-14 T 29-03-2018 IPR006260 TonB, C-terminal GO:0006810 MC49_RS05380 d2842a99efbca70b7a9e0454c6026128 265 SUPERFAMILY SSF74653 162 262 2.88E-16 T 29-03-2018 MC49_RS05380 d2842a99efbca70b7a9e0454c6026128 265 SUPERFAMILY SSF74653 84 95 2.88E-16 T 29-03-2018 MC49_RS05380 d2842a99efbca70b7a9e0454c6026128 265 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 188 262 3.0E-13 T 29-03-2018 IPR006260 TonB, C-terminal GO:0006810 MC49_RS05380 d2842a99efbca70b7a9e0454c6026128 265 Gene3D G3DSA:3.30.1150.10 160 262 2.6E-17 T 29-03-2018 MC49_RS02305 884e8288faffa92fdbb1d8a780f128a4 112 SUPERFAMILY SSF47413 13 79 3.66E-13 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS02305 884e8288faffa92fdbb1d8a780f128a4 112 SMART SM00530 20 75 4.0E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS02305 884e8288faffa92fdbb1d8a780f128a4 112 Gene3D G3DSA:1.10.260.40 7 87 1.9E-12 T 29-03-2018 MC49_RS02305 884e8288faffa92fdbb1d8a780f128a4 112 Pfam PF01381 Helix-turn-helix 21 72 1.3E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS15685 721e44a0fbcc2c80b115c6aca597e74c 135 ProSitePatterns PS00935 Glyoxalase I signature 2. 69 81 - T 29-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 MC49_RS15685 721e44a0fbcc2c80b115c6aca597e74c 135 TIGRFAM TIGR00068 glyox_I: lactoylglutathione lyase 2 134 8.0E-68 T 29-03-2018 IPR004361 Glyoxalase I GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 MC49_RS15685 721e44a0fbcc2c80b115c6aca597e74c 135 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 123 1.8E-26 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MC49_RS15685 721e44a0fbcc2c80b115c6aca597e74c 135 ProSitePatterns PS00934 Glyoxalase I signature 1. 5 26 - T 29-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 MC49_RS15685 721e44a0fbcc2c80b115c6aca597e74c 135 Gene3D G3DSA:3.10.180.10 1 135 3.6E-38 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MC49_RS15685 721e44a0fbcc2c80b115c6aca597e74c 135 SUPERFAMILY SSF54593 1 128 5.64E-36 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MC49_RS07715 7cfd83838fc50a8ac912fdb7e96a6489 386 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 12 384 7.3E-162 T 29-03-2018 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain MC49_RS07715 7cfd83838fc50a8ac912fdb7e96a6489 386 SUPERFAMILY SSF56059 1 168 5.3E-94 T 29-03-2018 MC49_RS07715 7cfd83838fc50a8ac912fdb7e96a6489 386 SUPERFAMILY SSF56059 266 383 5.3E-94 T 29-03-2018 MC49_RS07715 7cfd83838fc50a8ac912fdb7e96a6489 386 SUPERFAMILY SSF52440 174 279 5.47E-41 T 29-03-2018 IPR016185 Pre-ATP-grasp domain MC49_RS00740 c105c04497761481a363260ad220ca67 785 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 356 375 4.8E-56 T 29-03-2018 MC49_RS00740 c105c04497761481a363260ad220ca67 785 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 595 611 4.8E-56 T 29-03-2018 MC49_RS00740 c105c04497761481a363260ad220ca67 785 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 673 692 4.8E-56 T 29-03-2018 MC49_RS00740 c105c04497761481a363260ad220ca67 785 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 726 744 4.8E-56 T 29-03-2018 MC49_RS00740 c105c04497761481a363260ad220ca67 785 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 703 722 4.8E-56 T 29-03-2018 MC49_RS00740 c105c04497761481a363260ad220ca67 785 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 10 201 1.5E-39 T 29-03-2018 IPR003111 Lon, substrate-binding domain MC49_RS00740 c105c04497761481a363260ad220ca67 785 SUPERFAMILY SSF52540 313 586 4.65E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS00740 c105c04497761481a363260ad220ca67 785 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 352 489 4.4E-17 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MC49_RS00740 c105c04497761481a363260ad220ca67 785 Gene3D G3DSA:3.40.50.300 313 490 8.9E-30 T 29-03-2018 MC49_RS00740 c105c04497761481a363260ad220ca67 785 SMART SM00382 348 492 2.4E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS00740 c105c04497761481a363260ad220ca67 785 SUPERFAMILY SSF88697 10 201 2.36E-48 T 29-03-2018 IPR015947 PUA-like domain MC49_RS00740 c105c04497761481a363260ad220ca67 785 SUPERFAMILY SSF54211 595 770 2.69E-59 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MC49_RS00740 c105c04497761481a363260ad220ca67 785 TIGRFAM TIGR00763 lon: endopeptidase La 12 771 0.0 T 29-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 MC49_RS00740 c105c04497761481a363260ad220ca67 785 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 570 772 1.9E-97 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 MC49_RS00740 c105c04497761481a363260ad220ca67 785 SMART SM00464 10 202 1.4E-78 T 29-03-2018 IPR003111 Lon, substrate-binding domain MC49_RS00740 c105c04497761481a363260ad220ca67 785 Gene3D G3DSA:2.30.130.40 1 118 3.2E-28 T 29-03-2018 MC49_RS00740 c105c04497761481a363260ad220ca67 785 Gene3D G3DSA:1.10.8.60 491 584 3.5E-33 T 29-03-2018 MC49_RS00740 c105c04497761481a363260ad220ca67 785 Hamap MF_01973 Lon protease [lon]. 11 772 72.488 T 29-03-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 MC49_RS00740 c105c04497761481a363260ad220ca67 785 Gene3D G3DSA:1.10.4060.10 121 211 1.2E-28 T 29-03-2018 MC49_RS00740 c105c04497761481a363260ad220ca67 785 PIRSF PIRSF001174 1 775 0.0 T 29-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 MC49_RS00740 c105c04497761481a363260ad220ca67 785 Gene3D G3DSA:3.30.230.10 585 772 1.2E-70 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MC49_RS05645 087a22266c65b394026f16fb8f74456c 145 SMART SM00450 41 139 2.6E-17 T 29-03-2018 IPR001763 Rhodanese-like domain MC49_RS05645 087a22266c65b394026f16fb8f74456c 145 Gene3D G3DSA:3.40.250.10 24 145 1.0E-19 T 29-03-2018 IPR001763 Rhodanese-like domain MC49_RS05645 087a22266c65b394026f16fb8f74456c 145 Pfam PF00581 Rhodanese-like domain 47 134 3.8E-13 T 29-03-2018 IPR001763 Rhodanese-like domain MC49_RS05645 087a22266c65b394026f16fb8f74456c 145 SUPERFAMILY SSF52821 16 141 1.31E-26 T 29-03-2018 IPR001763 Rhodanese-like domain MC49_RS09140 dd8cf59da1454edddc4c49b6da7415d9 180 Gene3D G3DSA:3.30.70.20 3 73 4.0E-17 T 29-03-2018 MC49_RS09140 dd8cf59da1454edddc4c49b6da7415d9 180 Gene3D G3DSA:3.30.70.20 112 162 2.5E-11 T 29-03-2018 MC49_RS09140 dd8cf59da1454edddc4c49b6da7415d9 180 TIGRFAM TIGR02951 DMSO_dmsB: dimethylsulfoxide reductase, chain B 4 156 4.8E-71 T 29-03-2018 IPR014297 Dimethylsulphoxide reductase, chain B MC49_RS09140 dd8cf59da1454edddc4c49b6da7415d9 180 Pfam PF13247 4Fe-4S dicluster domain 56 146 3.0E-27 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MC49_RS09140 dd8cf59da1454edddc4c49b6da7415d9 180 SUPERFAMILY SSF54862 4 176 1.15E-63 T 29-03-2018 MC49_RS09140 dd8cf59da1454edddc4c49b6da7415d9 180 Pfam PF12800 4Fe-4S binding domain 13 26 0.012 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MC49_RS09140 dd8cf59da1454edddc4c49b6da7415d9 180 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 92 103 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MC49_RS09140 dd8cf59da1454edddc4c49b6da7415d9 180 Gene3D G3DSA:3.30.70.20 74 111 4.5E-20 T 29-03-2018 MC49_RS10740 3960a25aa53a55d2f364d98036409809 416 SUPERFAMILY SSF63867 333 413 1.11E-24 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MC49_RS10740 3960a25aa53a55d2f364d98036409809 416 SUPERFAMILY SSF63882 12 181 2.49E-53 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MC49_RS10740 3960a25aa53a55d2f364d98036409809 416 Gene3D G3DSA:2.170.190.11 56 147 7.6E-27 T 29-03-2018 MC49_RS10740 3960a25aa53a55d2f364d98036409809 416 SMART SM00852 186 323 2.4E-41 T 29-03-2018 IPR001453 MoaB/Mog domain MC49_RS10740 3960a25aa53a55d2f364d98036409809 416 Pfam PF00994 Probable molybdopterin binding domain 186 321 1.1E-24 T 29-03-2018 IPR001453 MoaB/Mog domain MC49_RS10740 3960a25aa53a55d2f364d98036409809 416 Pfam PF03454 MoeA C-terminal region (domain IV) 337 409 4.8E-19 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MC49_RS10740 3960a25aa53a55d2f364d98036409809 416 Gene3D G3DSA:3.40.980.10 156 330 5.0E-52 T 29-03-2018 IPR001453 MoaB/Mog domain MC49_RS10740 3960a25aa53a55d2f364d98036409809 416 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 182 319 1.4E-33 T 29-03-2018 IPR001453 MoaB/Mog domain MC49_RS10740 3960a25aa53a55d2f364d98036409809 416 Gene3D G3DSA:2.40.340.10 335 407 5.3E-20 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MC49_RS10740 3960a25aa53a55d2f364d98036409809 416 Pfam PF03453 MoeA N-terminal region (domain I and II) 13 173 1.1E-41 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MC49_RS10740 3960a25aa53a55d2f364d98036409809 416 SUPERFAMILY SSF53218 183 328 6.15E-43 T 29-03-2018 IPR001453 MoaB/Mog domain MC49_RS10740 3960a25aa53a55d2f364d98036409809 416 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 259 292 - T 29-03-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 MC49_RS01115 32f6346e309d9de2d43ecae356563576 388 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 76 247 9.1E-10 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MC49_RS01115 32f6346e309d9de2d43ecae356563576 388 Gene3D G3DSA:1.10.287.470 121 174 2.5E-5 T 29-03-2018 MC49_RS01115 32f6346e309d9de2d43ecae356563576 388 Gene3D G3DSA:3.90.1170.30 43 120 4.1E-6 T 29-03-2018 MC49_RS01115 32f6346e309d9de2d43ecae356563576 388 SUPERFAMILY SSF111369 63 197 3.14E-12 T 29-03-2018 MC49_RS01115 32f6346e309d9de2d43ecae356563576 388 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 56 378 6.9E-53 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MC49_RS01115 32f6346e309d9de2d43ecae356563576 388 Gene3D G3DSA:2.40.50.100 176 291 7.6E-5 T 29-03-2018 MC49_RS05130 90d76063d5d086d3880893a663c087af 629 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 368 391 - T 29-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 MC49_RS05130 90d76063d5d086d3880893a663c087af 629 SUPERFAMILY SSF51905 6 66 6.63E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS05130 90d76063d5d086d3880893a663c087af 629 SUPERFAMILY SSF51905 97 261 6.63E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS05130 90d76063d5d086d3880893a663c087af 629 Pfam PF01134 Glucose inhibited division protein A 8 398 2.4E-167 T 29-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 MC49_RS05130 90d76063d5d086d3880893a663c087af 629 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 7 622 7.1E-295 T 29-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 MC49_RS05130 90d76063d5d086d3880893a663c087af 629 Pfam PF13932 GidA associated domain 402 616 6.9E-77 T 29-03-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 MC49_RS05130 90d76063d5d086d3880893a663c087af 629 SMART SM01228 546 617 4.3E-43 T 29-03-2018 MC49_RS05130 90d76063d5d086d3880893a663c087af 629 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 5 624 42.494 T 29-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 MC49_RS05130 90d76063d5d086d3880893a663c087af 629 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 273 287 - T 29-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 MC49_RS05130 90d76063d5d086d3880893a663c087af 629 Gene3D G3DSA:3.50.50.60 5 264 3.0E-75 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS15565 55776f867c8d3ac200a40ac4f839aa86 167 Gene3D G3DSA:3.40.30.10 8 167 2.5E-20 T 29-03-2018 MC49_RS15565 55776f867c8d3ac200a40ac4f839aa86 167 SUPERFAMILY SSF52833 4 164 1.63E-38 T 29-03-2018 IPR012336 Thioredoxin-like fold MC49_RS15565 55776f867c8d3ac200a40ac4f839aa86 167 ProSitePatterns PS01265 Tpx family signature. 84 95 - T 29-03-2018 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 MC49_RS15565 55776f867c8d3ac200a40ac4f839aa86 167 Pfam PF08534 Redoxin 21 163 1.2E-24 T 29-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 MC49_RS15565 55776f867c8d3ac200a40ac4f839aa86 167 Hamap MF_00269 Probable thiol peroxidase [tpx]. 4 167 38.436 T 29-03-2018 IPR002065 Putative thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 MC49_RS07145 b9e7c78761c9ad31f93d01e0b20bde61 233 Pfam PF00970 Oxidoreductase FAD-binding domain 6 95 9.9E-5 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 MC49_RS07145 b9e7c78761c9ad31f93d01e0b20bde61 233 PRINTS PR00410 Phenol hydroxylase reductase family signature 31 43 2.8E-13 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MC49_RS07145 b9e7c78761c9ad31f93d01e0b20bde61 233 PRINTS PR00410 Phenol hydroxylase reductase family signature 47 54 2.8E-13 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MC49_RS07145 b9e7c78761c9ad31f93d01e0b20bde61 233 PRINTS PR00410 Phenol hydroxylase reductase family signature 107 126 2.8E-13 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MC49_RS07145 b9e7c78761c9ad31f93d01e0b20bde61 233 PRINTS PR00410 Phenol hydroxylase reductase family signature 132 141 2.8E-13 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MC49_RS07145 b9e7c78761c9ad31f93d01e0b20bde61 233 PRINTS PR00410 Phenol hydroxylase reductase family signature 91 100 2.8E-13 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MC49_RS07145 b9e7c78761c9ad31f93d01e0b20bde61 233 SUPERFAMILY SSF63380 3 97 1.13E-20 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MC49_RS07145 b9e7c78761c9ad31f93d01e0b20bde61 233 Gene3D G3DSA:2.40.30.10 2 98 2.4E-17 T 29-03-2018 MC49_RS07145 b9e7c78761c9ad31f93d01e0b20bde61 233 Gene3D G3DSA:3.40.50.80 99 233 1.2E-23 T 29-03-2018 MC49_RS07145 b9e7c78761c9ad31f93d01e0b20bde61 233 SUPERFAMILY SSF52343 100 231 3.54E-35 T 29-03-2018 MC49_RS07145 b9e7c78761c9ad31f93d01e0b20bde61 233 Pfam PF00175 Oxidoreductase NAD-binding domain 108 211 4.0E-21 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MC49_RS09315 5249b861c801564b344ab9e778eae62e 192 Gene3D G3DSA:2.60.60.30 18 186 1.2E-67 T 29-03-2018 MC49_RS09315 5249b861c801564b344ab9e778eae62e 192 Pfam PF02342 TerD domain 1 187 2.0E-85 T 29-03-2018 IPR003325 TerD domain GO:0006950 MC49_RS03670 bb56486a42435430c00af1b481ae2bc0 267 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 232 5.4E-28 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 MC49_RS03670 bb56486a42435430c00af1b481ae2bc0 267 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 261 1.1E-60 T 29-03-2018 IPR023214 HAD-like domain MC49_RS03670 bb56486a42435430c00af1b481ae2bc0 267 ProSitePatterns PS01228 Hypothetical cof family signature 1. 4 15 - T 29-03-2018 MC49_RS03670 bb56486a42435430c00af1b481ae2bc0 267 ProSitePatterns PS01229 Hypothetical cof family signature 2. 213 235 - T 29-03-2018 MC49_RS03670 bb56486a42435430c00af1b481ae2bc0 267 Gene3D G3DSA:3.40.50.1000 1 267 1.2E-35 T 29-03-2018 IPR023214 HAD-like domain MC49_RS03670 bb56486a42435430c00af1b481ae2bc0 267 SUPERFAMILY SSF56784 1 264 1.42E-64 T 29-03-2018 IPR023214 HAD-like domain MC49_RS03670 bb56486a42435430c00af1b481ae2bc0 267 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 261 2.1E-60 T 29-03-2018 IPR000150 Cof family GO:0016787 MC49_RS00600 43659abe6806c69cccb535b50bd443ca 624 Pfam PF00183 Hsp90 protein 215 622 1.8E-124 T 29-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 MC49_RS00600 43659abe6806c69cccb535b50bd443ca 624 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 29 184 5.0E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS00600 43659abe6806c69cccb535b50bd443ca 624 Gene3D G3DSA:3.30.565.10 31 224 5.7E-53 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS00600 43659abe6806c69cccb535b50bd443ca 624 PIRSF PIRSF002583 2 624 2.6E-218 T 29-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 MC49_RS00600 43659abe6806c69cccb535b50bd443ca 624 SMART SM00387 29 186 5.4E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS00600 43659abe6806c69cccb535b50bd443ca 624 SUPERFAMILY SSF54211 230 485 2.05E-101 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MC49_RS00600 43659abe6806c69cccb535b50bd443ca 624 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 27 36 - T 29-03-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0006950|GO:0051082 MC49_RS00600 43659abe6806c69cccb535b50bd443ca 624 SUPERFAMILY SSF55874 6 215 7.47E-66 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS00600 43659abe6806c69cccb535b50bd443ca 624 Hamap MF_00505 Chaperone protein HtpG [htpG]. 4 623 32.725 T 29-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 MC49_RS00600 43659abe6806c69cccb535b50bd443ca 624 SUPERFAMILY SSF110942 510 623 6.28E-34 T 29-03-2018 MC49_RS00600 43659abe6806c69cccb535b50bd443ca 624 PRINTS PR00775 90kDa heat shock protein signature 192 210 6.5E-65 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal MC49_RS00600 43659abe6806c69cccb535b50bd443ca 624 PRINTS PR00775 90kDa heat shock protein signature 28 50 6.5E-65 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal MC49_RS00600 43659abe6806c69cccb535b50bd443ca 624 PRINTS PR00775 90kDa heat shock protein signature 174 191 6.5E-65 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal MC49_RS00600 43659abe6806c69cccb535b50bd443ca 624 PRINTS PR00775 90kDa heat shock protein signature 95 112 6.5E-65 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal MC49_RS00600 43659abe6806c69cccb535b50bd443ca 624 PRINTS PR00775 90kDa heat shock protein signature 7 27 6.5E-65 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal MC49_RS00600 43659abe6806c69cccb535b50bd443ca 624 PRINTS PR00775 90kDa heat shock protein signature 122 144 6.5E-65 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal MC49_RS00600 43659abe6806c69cccb535b50bd443ca 624 PRINTS PR00775 90kDa heat shock protein signature 77 94 6.5E-65 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal MC49_RS08485 a75fe28619ccab595b1080a7664263fe 463 PIRSF PIRSF004729 1 463 1.5E-168 T 29-03-2018 IPR006230 Protein MutL MC49_RS08485 a75fe28619ccab595b1080a7664263fe 463 Pfam PF13941 MutL protein 4 456 7.2E-130 T 29-03-2018 IPR006230 Protein MutL MC49_RS08485 a75fe28619ccab595b1080a7664263fe 463 Gene3D G3DSA:3.30.420.40 1 276 4.4E-4 T 29-03-2018 MC49_RS08485 a75fe28619ccab595b1080a7664263fe 463 TIGRFAM TIGR01319 glmL_fam: conserved hypothetical protein 6 462 1.7E-194 T 29-03-2018 IPR006230 Protein MutL MC49_RS14360 f8920db6a9accb80e67be442178b4469 1297 SMART SM00847 460 556 1.8E-34 T 29-03-2018 IPR007502 Helicase-associated domain GO:0004386 MC49_RS14360 f8920db6a9accb80e67be442178b4469 1297 SUPERFAMILY SSF52540 70 593 1.06E-110 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS14360 f8920db6a9accb80e67be442178b4469 1297 Pfam PF00270 DEAD/DEAH box helicase 81 229 1.1E-6 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MC49_RS14360 f8920db6a9accb80e67be442178b4469 1297 Gene3D G3DSA:3.40.50.300 72 231 3.8E-29 T 29-03-2018 MC49_RS14360 f8920db6a9accb80e67be442178b4469 1297 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 619 696 1.6E-18 T 29-03-2018 IPR011709 Domain of unknown function DUF1605 MC49_RS14360 f8920db6a9accb80e67be442178b4469 1297 SMART SM00382 88 304 1.9E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS14360 f8920db6a9accb80e67be442178b4469 1297 Pfam PF04408 Helicase associated domain (HA2) 462 553 4.0E-15 T 29-03-2018 IPR007502 Helicase-associated domain GO:0004386 MC49_RS14360 f8920db6a9accb80e67be442178b4469 1297 SMART SM00490 300 400 6.6E-15 T 29-03-2018 IPR001650 Helicase, C-terminal MC49_RS14360 f8920db6a9accb80e67be442178b4469 1297 Gene3D G3DSA:3.40.50.300 249 420 7.0E-45 T 29-03-2018 MC49_RS14360 f8920db6a9accb80e67be442178b4469 1297 Pfam PF00271 Helicase conserved C-terminal domain 282 399 3.1E-11 T 29-03-2018 IPR001650 Helicase, C-terminal MC49_RS14360 f8920db6a9accb80e67be442178b4469 1297 Pfam PF11898 Domain of unknown function (DUF3418) 710 1294 8.5E-231 T 29-03-2018 IPR024590 RNA helicase HrpA, C-terminal MC49_RS14360 f8920db6a9accb80e67be442178b4469 1297 SMART SM00487 71 255 1.7E-27 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MC49_RS14360 f8920db6a9accb80e67be442178b4469 1297 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 9 1294 0.0 T 29-03-2018 IPR010222 RNA helicase HrpA GO:0004004 MC49_RS11665 714327e648e206a0929c7efc918e8eb2 99 SUPERFAMILY SSF54285 4 78 1.57E-24 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp MC49_RS11665 714327e648e206a0929c7efc918e8eb2 99 Pfam PF03658 RnfH family Ubiquitin 4 86 9.5E-33 T 29-03-2018 IPR005346 RnfH protein MC49_RS11665 714327e648e206a0929c7efc918e8eb2 99 Hamap MF_00460 Protein RnfH [rnfH]. 4 94 24.458 T 29-03-2018 IPR005346 RnfH protein MC49_RS11665 714327e648e206a0929c7efc918e8eb2 99 Gene3D G3DSA:3.10.20.280 1 87 2.2E-32 T 29-03-2018 IPR005346 RnfH protein MC49_RS02700 ca8b9d819c31c0e5d651b0fd52e1d0e7 154 SUPERFAMILY SSF48452 27 140 1.52E-18 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MC49_RS02700 ca8b9d819c31c0e5d651b0fd52e1d0e7 154 Gene3D G3DSA:1.25.40.10 20 152 4.4E-21 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MC49_RS02700 ca8b9d819c31c0e5d651b0fd52e1d0e7 154 Pfam PF13181 Tetratricopeptide repeat 107 135 0.0012 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MC49_RS02700 ca8b9d819c31c0e5d651b0fd52e1d0e7 154 Pfam PF07720 Tetratricopeptide repeat 39 70 4.1E-6 T 29-03-2018 IPR011716 Tetratricopeptide TPR-3 MC49_RS02700 ca8b9d819c31c0e5d651b0fd52e1d0e7 154 Pfam PF07720 Tetratricopeptide repeat 72 104 3.1E-8 T 29-03-2018 IPR011716 Tetratricopeptide TPR-3 MC49_RS02700 ca8b9d819c31c0e5d651b0fd52e1d0e7 154 PIRSF PIRSF003165 1 153 3.0E-36 T 29-03-2018 IPR016379 Type III secretion system, low calcium response, chaperone LcrH/SycD, subgroup MC49_RS02700 ca8b9d819c31c0e5d651b0fd52e1d0e7 154 PRINTS PR01595 Gram-negative bacterial type III secretion SycD chaperone signature 23 46 7.1E-10 T 29-03-2018 IPR005415 Type III secretion system, low calcium response, chaperone LcrH/SycD GO:0006950 MC49_RS02700 ca8b9d819c31c0e5d651b0fd52e1d0e7 154 PRINTS PR01595 Gram-negative bacterial type III secretion SycD chaperone signature 48 67 7.1E-10 T 29-03-2018 IPR005415 Type III secretion system, low calcium response, chaperone LcrH/SycD GO:0006950 MC49_RS02700 ca8b9d819c31c0e5d651b0fd52e1d0e7 154 PRINTS PR01595 Gram-negative bacterial type III secretion SycD chaperone signature 72 94 7.1E-10 T 29-03-2018 IPR005415 Type III secretion system, low calcium response, chaperone LcrH/SycD GO:0006950 MC49_RS02700 ca8b9d819c31c0e5d651b0fd52e1d0e7 154 PRINTS PR01595 Gram-negative bacterial type III secretion SycD chaperone signature 104 126 7.1E-10 T 29-03-2018 IPR005415 Type III secretion system, low calcium response, chaperone LcrH/SycD GO:0006950 MC49_RS02700 ca8b9d819c31c0e5d651b0fd52e1d0e7 154 SMART SM00028 71 104 0.0044 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MC49_RS02700 ca8b9d819c31c0e5d651b0fd52e1d0e7 154 SMART SM00028 105 138 3.1 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MC49_RS03605 501893b3ca5847863f2f680622cdb2ad 632 SUPERFAMILY SSF55874 2 201 1.22E-56 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS03605 501893b3ca5847863f2f680622cdb2ad 632 Pfam PF08676 MutL C terminal dimerisation domain 452 582 5.9E-20 T 29-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 MC49_RS03605 501893b3ca5847863f2f680622cdb2ad 632 SUPERFAMILY SSF118116 451 629 1.44E-32 T 29-03-2018 MC49_RS03605 501893b3ca5847863f2f680622cdb2ad 632 SUPERFAMILY SSF54211 191 330 1.97E-36 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MC49_RS03605 501893b3ca5847863f2f680622cdb2ad 632 SMART SM01340 212 330 5.8E-55 T 29-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 MC49_RS03605 501893b3ca5847863f2f680622cdb2ad 632 Gene3D G3DSA:3.30.565.10 1 216 2.3E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS03605 501893b3ca5847863f2f680622cdb2ad 632 Gene3D G3DSA:3.30.230.10 217 329 1.0E-29 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MC49_RS03605 501893b3ca5847863f2f680622cdb2ad 632 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 24 120 3.1E-12 T 29-03-2018 MC49_RS03605 501893b3ca5847863f2f680622cdb2ad 632 SMART SM00853 455 598 5.9E-7 T 29-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 MC49_RS03605 501893b3ca5847863f2f680622cdb2ad 632 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 1 629 25.261 T 29-03-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 MC49_RS03605 501893b3ca5847863f2f680622cdb2ad 632 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 1 310 1.6E-100 T 29-03-2018 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 MC49_RS03605 501893b3ca5847863f2f680622cdb2ad 632 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 93 99 - T 29-03-2018 IPR014762 DNA mismatch repair, conserved site MC49_RS03605 501893b3ca5847863f2f680622cdb2ad 632 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 214 329 1.0E-36 T 29-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 MC49_RS13550 e3909fd5a33f12bd8de1d9b8775b54c4 525 Pfam PF00571 CBS domain 132 177 7.2E-5 T 29-03-2018 IPR000644 CBS domain MC49_RS13550 e3909fd5a33f12bd8de1d9b8775b54c4 525 Pfam PF00571 CBS domain 186 239 8.1E-5 T 29-03-2018 IPR000644 CBS domain MC49_RS13550 e3909fd5a33f12bd8de1d9b8775b54c4 525 PIRSF PIRSF000130 36 524 8.4E-196 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 MC49_RS13550 e3909fd5a33f12bd8de1d9b8775b54c4 525 SUPERFAMILY SSF51412 39 127 1.14E-124 T 29-03-2018 MC49_RS13550 e3909fd5a33f12bd8de1d9b8775b54c4 525 SUPERFAMILY SSF51412 254 514 1.14E-124 T 29-03-2018 MC49_RS13550 e3909fd5a33f12bd8de1d9b8775b54c4 525 SMART SM01240 44 510 0.0 T 29-03-2018 MC49_RS13550 e3909fd5a33f12bd8de1d9b8775b54c4 525 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 332 344 - T 29-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 MC49_RS13550 e3909fd5a33f12bd8de1d9b8775b54c4 525 SUPERFAMILY SSF54631 132 240 4.67E-24 T 29-03-2018 MC49_RS13550 e3909fd5a33f12bd8de1d9b8775b54c4 525 Gene3D G3DSA:3.20.20.70 32 519 3.8E-114 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS13550 e3909fd5a33f12bd8de1d9b8775b54c4 525 SMART SM00116 133 181 5.3E-10 T 29-03-2018 IPR000644 CBS domain MC49_RS13550 e3909fd5a33f12bd8de1d9b8775b54c4 525 SMART SM00116 195 243 8.4E-9 T 29-03-2018 IPR000644 CBS domain MC49_RS13550 e3909fd5a33f12bd8de1d9b8775b54c4 525 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 45 491 8.0E-196 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 MC49_RS13550 e3909fd5a33f12bd8de1d9b8775b54c4 525 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 45 523 83.782 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 MC49_RS13550 e3909fd5a33f12bd8de1d9b8775b54c4 525 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 45 510 6.9E-161 T 29-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 MC49_RS12845 1ce2f2e6fb0bcf4cffad2df4bba18cc8 904 Gene3D G3DSA:1.20.120.160 778 903 9.3E-6 T 29-03-2018 MC49_RS12845 1ce2f2e6fb0bcf4cffad2df4bba18cc8 904 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 564 669 2.0E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS12845 1ce2f2e6fb0bcf4cffad2df4bba18cc8 904 Pfam PF16359 RcsD-ABL domain 679 779 1.7E-30 T 29-03-2018 IPR032306 Phosphotransferase RcsD, RcsD-ABL domain MC49_RS12845 1ce2f2e6fb0bcf4cffad2df4bba18cc8 904 SUPERFAMILY SSF47226 815 893 4.19E-10 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MC49_RS12845 1ce2f2e6fb0bcf4cffad2df4bba18cc8 904 Pfam PF01627 Hpt domain 818 896 1.7E-5 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MC49_RS12845 1ce2f2e6fb0bcf4cffad2df4bba18cc8 904 Gene3D G3DSA:3.30.565.10 477 669 2.1E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS12845 1ce2f2e6fb0bcf4cffad2df4bba18cc8 904 SUPERFAMILY SSF55874 499 672 2.05E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS12845 1ce2f2e6fb0bcf4cffad2df4bba18cc8 904 Gene3D G3DSA:3.30.450.20 373 463 0.001 T 29-03-2018 MC49_RS06385 9f53dac3a07dc40b11aa9f517de66e07 708 SUPERFAMILY SSF54980 411 488 7.91E-25 T 29-03-2018 IPR035647 EF-G domain III/V-like MC49_RS06385 9f53dac3a07dc40b11aa9f517de66e07 708 SMART SM00889 487 612 2.5E-66 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 MC49_RS06385 9f53dac3a07dc40b11aa9f517de66e07 708 Hamap MF_00054_B Elongation factor G [fusA]. 6 705 110.681 T 29-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MC49_RS06385 9f53dac3a07dc40b11aa9f517de66e07 708 SMART SM00838 614 701 1.6E-59 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like MC49_RS06385 9f53dac3a07dc40b11aa9f517de66e07 708 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 187 1.4E-30 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MC49_RS06385 9f53dac3a07dc40b11aa9f517de66e07 708 Gene3D G3DSA:3.40.50.300 1 289 8.7E-58 T 29-03-2018 MC49_RS06385 9f53dac3a07dc40b11aa9f517de66e07 708 SUPERFAMILY SSF52540 6 288 2.41E-105 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS06385 9f53dac3a07dc40b11aa9f517de66e07 708 Pfam PF00679 Elongation factor G C-terminus 614 699 2.5E-31 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like MC49_RS06385 9f53dac3a07dc40b11aa9f517de66e07 708 Pfam PF03764 Elongation factor G, domain IV 486 612 2.1E-43 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 MC49_RS06385 9f53dac3a07dc40b11aa9f517de66e07 708 Gene3D G3DSA:3.30.70.870 405 500 1.5E-37 T 29-03-2018 MC49_RS06385 9f53dac3a07dc40b11aa9f517de66e07 708 Gene3D G3DSA:3.30.230.10 501 627 1.9E-39 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MC49_RS06385 9f53dac3a07dc40b11aa9f517de66e07 708 Pfam PF14492 Elongation Factor G, domain II 411 485 1.3E-34 T 29-03-2018 MC49_RS06385 9f53dac3a07dc40b11aa9f517de66e07 708 Pfam PF03144 Elongation factor Tu domain 2 331 398 2.0E-17 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MC49_RS06385 9f53dac3a07dc40b11aa9f517de66e07 708 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.8E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS06385 9f53dac3a07dc40b11aa9f517de66e07 708 PRINTS PR00315 GTP-binding elongation factor signature 101 112 1.8E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS06385 9f53dac3a07dc40b11aa9f517de66e07 708 PRINTS PR00315 GTP-binding elongation factor signature 137 146 1.8E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS06385 9f53dac3a07dc40b11aa9f517de66e07 708 PRINTS PR00315 GTP-binding elongation factor signature 85 95 1.8E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS06385 9f53dac3a07dc40b11aa9f517de66e07 708 PRINTS PR00315 GTP-binding elongation factor signature 12 25 1.8E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS06385 9f53dac3a07dc40b11aa9f517de66e07 708 SUPERFAMILY SSF54211 486 613 1.72E-37 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MC49_RS06385 9f53dac3a07dc40b11aa9f517de66e07 708 SUPERFAMILY SSF50447 271 411 4.2E-34 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain MC49_RS06385 9f53dac3a07dc40b11aa9f517de66e07 708 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site MC49_RS06385 9f53dac3a07dc40b11aa9f517de66e07 708 SUPERFAMILY SSF54980 614 703 1.29E-29 T 29-03-2018 IPR035647 EF-G domain III/V-like MC49_RS06385 9f53dac3a07dc40b11aa9f517de66e07 708 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 706 0.0 T 29-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MC49_RS06385 9f53dac3a07dc40b11aa9f517de66e07 708 Pfam PF00009 Elongation factor Tu GTP binding domain 9 288 7.8E-67 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS06385 9f53dac3a07dc40b11aa9f517de66e07 708 Gene3D G3DSA:2.40.30.10 290 404 2.5E-27 T 29-03-2018 MC49_RS06385 9f53dac3a07dc40b11aa9f517de66e07 708 Gene3D G3DSA:3.30.70.240 628 705 2.7E-31 T 29-03-2018 MC49_RS16540 0def0bd96cf44332c2cbc79e143fd308 303 SUPERFAMILY SSF46785 10 119 1.66E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS16540 0def0bd96cf44332c2cbc79e143fd308 303 Pfam PF03466 LysR substrate binding domain 97 284 1.4E-27 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS16540 0def0bd96cf44332c2cbc79e143fd308 303 SUPERFAMILY SSF53850 96 286 4.16E-26 T 29-03-2018 MC49_RS16540 0def0bd96cf44332c2cbc79e143fd308 303 Gene3D G3DSA:1.10.10.10 8 93 1.4E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS16540 0def0bd96cf44332c2cbc79e143fd308 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 71 8.1E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS16540 0def0bd96cf44332c2cbc79e143fd308 303 Gene3D G3DSA:3.40.190.10 183 262 1.1E-15 T 29-03-2018 MC49_RS16540 0def0bd96cf44332c2cbc79e143fd308 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 49 3.2E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS16540 0def0bd96cf44332c2cbc79e143fd308 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 49 60 3.2E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS16540 0def0bd96cf44332c2cbc79e143fd308 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 39 3.2E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS16540 0def0bd96cf44332c2cbc79e143fd308 303 Gene3D G3DSA:3.40.190.10 99 182 3.0E-13 T 29-03-2018 MC49_RS09205 c79b26b0504ee9fa34b0cf1bd6c9e92c 465 SUPERFAMILY SSF54106 350 394 1.05E-9 T 29-03-2018 IPR018392 LysM domain MC49_RS09205 c79b26b0504ee9fa34b0cf1bd6c9e92c 465 Gene3D G3DSA:1.10.530.10 39 244 9.0E-34 T 29-03-2018 MC49_RS09205 c79b26b0504ee9fa34b0cf1bd6c9e92c 465 SUPERFAMILY SSF53955 97 242 7.67E-42 T 29-03-2018 IPR023346 Lysozyme-like domain MC49_RS09205 c79b26b0504ee9fa34b0cf1bd6c9e92c 465 SUPERFAMILY SSF54106 415 459 4.19E-9 T 29-03-2018 IPR018392 LysM domain MC49_RS09205 c79b26b0504ee9fa34b0cf1bd6c9e92c 465 Gene3D G3DSA:3.10.350.10 345 413 5.2E-15 T 29-03-2018 MC49_RS09205 c79b26b0504ee9fa34b0cf1bd6c9e92c 465 Pfam PF01476 LysM domain 416 457 2.2E-9 T 29-03-2018 IPR018392 LysM domain MC49_RS09205 c79b26b0504ee9fa34b0cf1bd6c9e92c 465 Pfam PF01476 LysM domain 352 394 3.1E-13 T 29-03-2018 IPR018392 LysM domain MC49_RS09205 c79b26b0504ee9fa34b0cf1bd6c9e92c 465 Gene3D G3DSA:3.10.350.10 414 464 1.5E-11 T 29-03-2018 MC49_RS09205 c79b26b0504ee9fa34b0cf1bd6c9e92c 465 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 119 147 - T 29-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 MC49_RS09205 c79b26b0504ee9fa34b0cf1bd6c9e92c 465 Pfam PF01464 Transglycosylase SLT domain 107 210 1.7E-26 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 MC49_RS09205 c79b26b0504ee9fa34b0cf1bd6c9e92c 465 SMART SM00257 351 395 1.6E-16 T 29-03-2018 IPR018392 LysM domain MC49_RS09205 c79b26b0504ee9fa34b0cf1bd6c9e92c 465 SMART SM00257 415 459 2.7E-9 T 29-03-2018 IPR018392 LysM domain MC49_RS11020 0da68c224691855e4858beb1f55b48a9 648 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS11020 0da68c224691855e4858beb1f55b48a9 648 Pfam PF02687 FtsX-like permease family 553 641 2.0E-9 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MC49_RS11020 0da68c224691855e4858beb1f55b48a9 648 Gene3D G3DSA:3.40.50.300 1 228 3.4E-65 T 29-03-2018 MC49_RS11020 0da68c224691855e4858beb1f55b48a9 648 Pfam PF00005 ABC transporter 24 172 7.0E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS11020 0da68c224691855e4858beb1f55b48a9 648 Pfam PF12704 MacB-like periplasmic core domain 272 490 1.5E-36 T 29-03-2018 IPR025857 MacB-like periplasmic core domain MC49_RS11020 0da68c224691855e4858beb1f55b48a9 648 SUPERFAMILY SSF52540 4 224 4.03E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS11020 0da68c224691855e4858beb1f55b48a9 648 SMART SM00382 33 220 1.5E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS14885 ef9c2ee9797b5495d5febd48acb28e02 152 SUPERFAMILY SSF55729 5 150 1.28E-35 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS14885 ef9c2ee9797b5495d5febd48acb28e02 152 Pfam PF13673 Acetyltransferase (GNAT) domain 48 146 2.0E-15 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MC49_RS14885 ef9c2ee9797b5495d5febd48acb28e02 152 Gene3D G3DSA:3.40.630.30 3 152 1.4E-32 T 29-03-2018 MC49_RS14080 2b891735a2763d18ece042d2d2825ec9 269 SUPERFAMILY SSF52540 3 217 3.87E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS14080 2b891735a2763d18ece042d2d2825ec9 269 SMART SM00382 29 199 2.3E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS14080 2b891735a2763d18ece042d2d2825ec9 269 Gene3D G3DSA:3.40.50.300 1 241 2.9E-53 T 29-03-2018 MC49_RS14080 2b891735a2763d18ece042d2d2825ec9 269 Pfam PF00005 ABC transporter 20 149 4.1E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS14080 2b891735a2763d18ece042d2d2825ec9 269 ProSitePatterns PS00211 ABC transporters family signature. 121 135 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS10200 8c50fe81ff8cb65346192d9e1cef8790 517 Pfam PF00795 Carbon-nitrogen hydrolase 223 477 9.3E-36 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MC49_RS10200 8c50fe81ff8cb65346192d9e1cef8790 517 Gene3D G3DSA:3.60.110.10 218 479 8.6E-35 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MC49_RS10200 8c50fe81ff8cb65346192d9e1cef8790 517 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 63 457 3.6E-101 T 29-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 MC49_RS10200 8c50fe81ff8cb65346192d9e1cef8790 517 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 10 495 23.483 T 29-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 MC49_RS10200 8c50fe81ff8cb65346192d9e1cef8790 517 SUPERFAMILY SSF56317 217 490 4.71E-36 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MC49_RS03515 f355edcb3376cd61e40b7c2a5e0d4621 456 Pfam PF01595 Domain of unknown function DUF21 6 197 4.5E-37 T 29-03-2018 IPR002550 Domain of unknown function DUF21 MC49_RS03515 f355edcb3376cd61e40b7c2a5e0d4621 456 SUPERFAMILY SSF56176 344 427 1.47E-23 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 MC49_RS03515 f355edcb3376cd61e40b7c2a5e0d4621 456 SUPERFAMILY SSF54631 200 335 1.46E-18 T 29-03-2018 MC49_RS03515 f355edcb3376cd61e40b7c2a5e0d4621 456 SMART SM01091 346 426 1.6E-30 T 29-03-2018 IPR005170 Transporter-associated domain MC49_RS03515 f355edcb3376cd61e40b7c2a5e0d4621 456 Pfam PF03471 Transporter associated domain 347 425 5.8E-23 T 29-03-2018 IPR005170 Transporter-associated domain MC49_RS03515 f355edcb3376cd61e40b7c2a5e0d4621 456 Gene3D G3DSA:3.10.580.10 193 345 3.9E-20 T 29-03-2018 MC49_RS03515 f355edcb3376cd61e40b7c2a5e0d4621 456 Gene3D G3DSA:3.30.465.10 346 438 1.6E-24 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 MC49_RS09810 4a140807dbcdc61d0e6272a5fafde6e1 356 Gene3D G3DSA:3.30.250.10 272 328 2.7E-25 T 29-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal MC49_RS09810 4a140807dbcdc61d0e6272a5fafde6e1 356 ProSitePatterns PS00321 recA signature. 215 223 - T 29-03-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 MC49_RS09810 4a140807dbcdc61d0e6272a5fafde6e1 356 SUPERFAMILY SSF54752 271 326 2.35E-21 T 29-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal MC49_RS09810 4a140807dbcdc61d0e6272a5fafde6e1 356 Gene3D G3DSA:3.40.50.300 28 270 1.2E-46 T 29-03-2018 MC49_RS09810 4a140807dbcdc61d0e6272a5fafde6e1 356 PRINTS PR00142 RecA protein signature 212 240 4.8E-84 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MC49_RS09810 4a140807dbcdc61d0e6272a5fafde6e1 356 PRINTS PR00142 RecA protein signature 95 124 4.8E-84 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MC49_RS09810 4a140807dbcdc61d0e6272a5fafde6e1 356 PRINTS PR00142 RecA protein signature 245 274 4.8E-84 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MC49_RS09810 4a140807dbcdc61d0e6272a5fafde6e1 356 PRINTS PR00142 RecA protein signature 299 316 4.8E-84 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MC49_RS09810 4a140807dbcdc61d0e6272a5fafde6e1 356 PRINTS PR00142 RecA protein signature 129 158 4.8E-84 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MC49_RS09810 4a140807dbcdc61d0e6272a5fafde6e1 356 PRINTS PR00142 RecA protein signature 167 196 4.8E-84 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MC49_RS09810 4a140807dbcdc61d0e6272a5fafde6e1 356 SUPERFAMILY SSF52540 5 269 1.02E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS09810 4a140807dbcdc61d0e6272a5fafde6e1 356 SMART SM00382 59 230 3.5E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS09810 4a140807dbcdc61d0e6272a5fafde6e1 356 Hamap MF_00268 Protein RecA [recA]. 7 331 50.98 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MC49_RS09810 4a140807dbcdc61d0e6272a5fafde6e1 356 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 6 326 1.2E-171 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MC49_RS09810 4a140807dbcdc61d0e6272a5fafde6e1 356 Pfam PF00154 recA bacterial DNA recombination protein 9 270 3.8E-142 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MC49_RS11455 f5fddae17c94b02ebfe9dd46741121ed 257 Pfam PF13505 Outer membrane protein beta-barrel domain 9 257 7.7E-18 T 29-03-2018 IPR027385 Outer membrane protein beta-barrel MC49_RS11455 f5fddae17c94b02ebfe9dd46741121ed 257 SUPERFAMILY SSF56925 22 103 1.28E-29 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MC49_RS11455 f5fddae17c94b02ebfe9dd46741121ed 257 SUPERFAMILY SSF56925 129 257 1.28E-29 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MC49_RS11455 f5fddae17c94b02ebfe9dd46741121ed 257 Gene3D G3DSA:2.40.160.20 8 257 2.2E-28 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MC49_RS12105 df0b1ca7ca8f2160fad45a63c81c3242 163 TIGRFAM TIGR02010 IscR: iron-sulfur cluster assembly transcription factor IscR 1 135 3.0E-65 T 29-03-2018 IPR010242 Transcription factor HTH, IscR GO:0003690|GO:0003700|GO:0006355 MC49_RS12105 df0b1ca7ca8f2160fad45a63c81c3242 163 Gene3D G3DSA:1.10.10.10 1 142 9.0E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS12105 df0b1ca7ca8f2160fad45a63c81c3242 163 SUPERFAMILY SSF46785 2 133 6.97E-36 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS12105 df0b1ca7ca8f2160fad45a63c81c3242 163 Pfam PF02082 Transcriptional regulator 1 83 1.5E-26 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type MC49_RS12105 df0b1ca7ca8f2160fad45a63c81c3242 163 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 132 6.6E-45 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type MC49_RS17380 35b80ae93b009b1bcdff50617edcb6ca 345 Gene3D G3DSA:3.40.50.150 104 345 4.3E-29 T 29-03-2018 MC49_RS17380 35b80ae93b009b1bcdff50617edcb6ca 345 SUPERFAMILY SSF53335 102 342 1.26E-37 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS17380 35b80ae93b009b1bcdff50617edcb6ca 345 SUPERFAMILY SSF46785 19 100 2.0E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS17380 35b80ae93b009b1bcdff50617edcb6ca 345 Pfam PF00891 O-methyltransferase 111 326 4.6E-40 T 29-03-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 MC49_RS17380 35b80ae93b009b1bcdff50617edcb6ca 345 PIRSF PIRSF005739 4 344 6.0E-48 T 29-03-2018 IPR016461 O-methyltransferase COMT-type GO:0008168 MC49_RS17380 35b80ae93b009b1bcdff50617edcb6ca 345 Gene3D G3DSA:1.10.10.10 12 103 3.9E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS05120 337b29f486a83b70c3c0baa43c43e6c0 153 SUPERFAMILY SSF54909 68 153 2.55E-19 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel MC49_RS05120 337b29f486a83b70c3c0baa43c43e6c0 153 Pfam PF01037 Lrp/AsnC ligand binding domain 77 144 3.9E-17 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MC49_RS05120 337b29f486a83b70c3c0baa43c43e6c0 153 Gene3D G3DSA:1.10.10.10 1 58 2.1E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS05120 337b29f486a83b70c3c0baa43c43e6c0 153 Pfam PF13404 AsnC-type helix-turn-helix domain 7 48 1.5E-13 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MC49_RS05120 337b29f486a83b70c3c0baa43c43e6c0 153 ProSitePatterns PS00519 AsnC-type HTH domain signature. 25 51 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site MC49_RS05120 337b29f486a83b70c3c0baa43c43e6c0 153 Gene3D G3DSA:3.30.70.920 60 150 2.7E-20 T 29-03-2018 MC49_RS05120 337b29f486a83b70c3c0baa43c43e6c0 153 SMART SM00344 7 114 1.2E-44 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MC49_RS05120 337b29f486a83b70c3c0baa43c43e6c0 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 1.3E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MC49_RS05120 337b29f486a83b70c3c0baa43c43e6c0 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 1.3E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MC49_RS05120 337b29f486a83b70c3c0baa43c43e6c0 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 1.3E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MC49_RS05120 337b29f486a83b70c3c0baa43c43e6c0 153 SUPERFAMILY SSF46785 5 67 3.96E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS00785 f32d4830fc276952c9abd91a883e59b1 663 SUPERFAMILY SSF81442 43 559 4.32E-177 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MC49_RS00785 f32d4830fc276952c9abd91a883e59b1 663 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 56 502 1.5E-134 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MC49_RS00785 f32d4830fc276952c9abd91a883e59b1 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 47 72 2.7E-94 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MC49_RS00785 f32d4830fc276952c9abd91a883e59b1 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 97 120 2.7E-94 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MC49_RS00785 f32d4830fc276952c9abd91a883e59b1 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 383 401 2.7E-94 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MC49_RS00785 f32d4830fc276952c9abd91a883e59b1 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 411 430 2.7E-94 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MC49_RS00785 f32d4830fc276952c9abd91a883e59b1 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 166 178 2.7E-94 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MC49_RS00785 f32d4830fc276952c9abd91a883e59b1 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 227 246 2.7E-94 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MC49_RS00785 f32d4830fc276952c9abd91a883e59b1 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 278 299 2.7E-94 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MC49_RS00785 f32d4830fc276952c9abd91a883e59b1 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 324 339 2.7E-94 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MC49_RS00785 f32d4830fc276952c9abd91a883e59b1 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 348 369 2.7E-94 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MC49_RS00785 f32d4830fc276952c9abd91a883e59b1 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 198 216 2.7E-94 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MC49_RS00785 f32d4830fc276952c9abd91a883e59b1 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 124 148 2.7E-94 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MC49_RS00785 f32d4830fc276952c9abd91a883e59b1 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 461 482 2.7E-94 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MC49_RS00785 f32d4830fc276952c9abd91a883e59b1 663 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 280 334 - T 29-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MC49_RS00785 f32d4830fc276952c9abd91a883e59b1 663 TIGRFAM TIGR02843 CyoB: cytochrome o ubiquinol oxidase, subunit I 2 647 0.0 T 29-03-2018 IPR014207 Cytochrome o ubiquinol oxidase, subunit I GO:0016682|GO:0055114 MetaCyc: PWY-7544 MC49_RS00785 f32d4830fc276952c9abd91a883e59b1 663 Gene3D G3DSA:1.10.287.70 573 640 1.5E-17 T 29-03-2018 MC49_RS00785 f32d4830fc276952c9abd91a883e59b1 663 Gene3D G3DSA:1.20.210.10 43 561 1.3E-184 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MC49_RS08225 e109f6b789a32096d9328e7ff22f8141 258 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 19 250 3.7E-74 T 29-03-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 MC49_RS08225 e109f6b789a32096d9328e7ff22f8141 258 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 18 249 41.892 T 29-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 MC49_RS08225 e109f6b789a32096d9328e7ff22f8141 258 SUPERFAMILY SSF53448 19 250 1.59E-58 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MC49_RS08225 e109f6b789a32096d9328e7ff22f8141 258 Gene3D G3DSA:3.90.550.10 13 258 1.3E-46 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MC49_RS08225 e109f6b789a32096d9328e7ff22f8141 258 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 21 248 3.5E-68 T 29-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 MC49_RS08225 e109f6b789a32096d9328e7ff22f8141 258 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 117 124 - T 29-03-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 MC49_RS07735 8270c98bb4ff4bb88ef7ea6a68d1aeb8 277 SUPERFAMILY SSF56300 16 272 4.1E-60 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like MC49_RS07735 8270c98bb4ff4bb88ef7ea6a68d1aeb8 277 Pfam PF00149 Calcineurin-like phosphoesterase 16 207 1.4E-18 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MC49_RS07735 8270c98bb4ff4bb88ef7ea6a68d1aeb8 277 Gene3D G3DSA:3.60.21.10 4 272 1.4E-39 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like MC49_RS07735 8270c98bb4ff4bb88ef7ea6a68d1aeb8 277 ProDom PD587589 PHOSPHODIESTERASE ICC METALLOPHOSPHOESTERASE CYCLIC REGULATOR LACZ AMP HYDROLASE 3'5'-CYCLIC-NUCLEOTIDE EXPRESSION 206 263 1.0E-19 T 29-03-2018 IPR013622 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA, C-terminal KEGG: 00230+3.1.4.53 MC49_RS07735 8270c98bb4ff4bb88ef7ea6a68d1aeb8 277 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 15 263 38.775 T 29-03-2018 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 MC49_RS01785 b7074edc41b2bc58e6a0a285995e8a87 156 Gene3D G3DSA:3.40.630.30 7 156 3.0E-22 T 29-03-2018 MC49_RS01785 b7074edc41b2bc58e6a0a285995e8a87 156 Pfam PF00583 Acetyltransferase (GNAT) family 42 134 2.5E-13 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MC49_RS01785 b7074edc41b2bc58e6a0a285995e8a87 156 SUPERFAMILY SSF55729 25 153 1.01E-21 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS05940 070566be05c662df947f5da577da3125 336 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 334 38.154 T 29-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MC49_RS05940 070566be05c662df947f5da577da3125 336 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 145 2.3E-31 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MC49_RS05940 070566be05c662df947f5da577da3125 336 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 149 165 - T 29-03-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MC49_RS05940 070566be05c662df947f5da577da3125 336 Gene3D G3DSA:3.30.360.10 163 308 2.6E-48 T 29-03-2018 MC49_RS05940 070566be05c662df947f5da577da3125 336 SUPERFAMILY SSF51735 2 179 1.84E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS05940 070566be05c662df947f5da577da3125 336 Gene3D G3DSA:3.40.50.720 1 162 6.0E-41 T 29-03-2018 MC49_RS05940 070566be05c662df947f5da577da3125 336 SUPERFAMILY SSF55347 154 308 3.83E-49 T 29-03-2018 MC49_RS05940 070566be05c662df947f5da577da3125 336 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 3 333 8.1E-122 T 29-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MC49_RS05940 070566be05c662df947f5da577da3125 336 SMART SM00859 3 146 6.8E-47 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MC49_RS05940 070566be05c662df947f5da577da3125 336 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 163 311 3.9E-15 T 29-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MC49_RS06640 2761075e832d1f1f319c8b3f2e8dd1c8 824 TIGRFAM TIGR03703 plsB: glycerol-3-phosphate O-acyltransferase 12 802 0.0 T 29-03-2018 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166|Reactome: R-HSA-2426168|Reactome: R-HSA-75109 MC49_RS06640 2761075e832d1f1f319c8b3f2e8dd1c8 824 Pfam PF01553 Acyltransferase 284 426 2.4E-26 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MC49_RS06640 2761075e832d1f1f319c8b3f2e8dd1c8 824 SUPERFAMILY SSF69593 239 490 6.67E-26 T 29-03-2018 MC49_RS06640 2761075e832d1f1f319c8b3f2e8dd1c8 824 Hamap MF_00393 Glycerol-3-phosphate acyltransferase [plsB]. 13 810 31.975 T 29-03-2018 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166|Reactome: R-HSA-2426168|Reactome: R-HSA-75109 MC49_RS06640 2761075e832d1f1f319c8b3f2e8dd1c8 824 PIRSF PIRSF500064 2 817 0.0 T 29-03-2018 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166|Reactome: R-HSA-2426168|Reactome: R-HSA-75109 MC49_RS06640 2761075e832d1f1f319c8b3f2e8dd1c8 824 Gene3D G3DSA:3.40.1130.10 231 503 1.6E-36 T 29-03-2018 MC49_RS06640 2761075e832d1f1f319c8b3f2e8dd1c8 824 PIRSF PIRSF000437 19 814 8.3E-302 T 29-03-2018 IPR022284 Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase GO:0008374|GO:0044255 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166 MC49_RS06640 2761075e832d1f1f319c8b3f2e8dd1c8 824 SMART SM00563 302 429 6.9E-31 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MC49_RS15855 ef48d8a539284d92ea20794df32e6c22 62 Pfam PF10636 Hemin uptake protein hemP 26 62 1.2E-17 T 29-03-2018 IPR019600 Hemin uptake protein HemP MC49_RS15855 ef48d8a539284d92ea20794df32e6c22 62 Gene3D G3DSA:2.10.70.10 26 62 3.6E-17 T 29-03-2018 MC49_RS14940 6fafe1233724630aeabea4b9c2b49266 249 Gene3D G3DSA:3.40.50.720 1 235 7.4E-56 T 29-03-2018 MC49_RS14940 6fafe1233724630aeabea4b9c2b49266 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 1.3E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS14940 6fafe1233724630aeabea4b9c2b49266 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 1.3E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS14940 6fafe1233724630aeabea4b9c2b49266 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 1.3E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS14940 6fafe1233724630aeabea4b9c2b49266 249 SUPERFAMILY SSF51735 2 231 8.25E-59 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS14940 6fafe1233724630aeabea4b9c2b49266 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 2.5E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS14940 6fafe1233724630aeabea4b9c2b49266 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 2.5E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS14940 6fafe1233724630aeabea4b9c2b49266 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 2.5E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS14940 6fafe1233724630aeabea4b9c2b49266 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 2.5E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS14940 6fafe1233724630aeabea4b9c2b49266 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 2.5E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS14940 6fafe1233724630aeabea4b9c2b49266 249 Pfam PF00106 short chain dehydrogenase 2 185 5.3E-50 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS14940 6fafe1233724630aeabea4b9c2b49266 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MC49_RS06540 904af34243029686ff2364745779b009 90 Gene3D G3DSA:4.10.520.10 1 90 1.3E-35 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 MC49_RS06540 904af34243029686ff2364745779b009 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 1.4E-19 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MC49_RS06540 904af34243029686ff2364745779b009 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 1.4E-19 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MC49_RS06540 904af34243029686ff2364745779b009 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 1.4E-19 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MC49_RS06540 904af34243029686ff2364745779b009 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 29-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 MC49_RS06540 904af34243029686ff2364745779b009 90 SUPERFAMILY SSF47729 1 90 1.77E-33 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 MC49_RS06540 904af34243029686ff2364745779b009 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 2.8E-34 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MC49_RS06540 904af34243029686ff2364745779b009 90 SMART SM00411 1 90 1.3E-45 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MC49_RS06665 9412ab4a8bc613b0aa5c31c4f7e289cf 119 Gene3D G3DSA:1.10.3100.10 15 99 2.0E-16 T 29-03-2018 IPR027910 YdiL-like domain MC49_RS06665 9412ab4a8bc613b0aa5c31c4f7e289cf 119 Pfam PF01381 Helix-turn-helix 26 80 4.2E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS06665 9412ab4a8bc613b0aa5c31c4f7e289cf 119 SMART SM00530 25 80 1.2E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS06665 9412ab4a8bc613b0aa5c31c4f7e289cf 119 SUPERFAMILY SSF47413 15 82 5.63E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS19130 d4af327c7afbe36c2a9ac13b992e70ce 390 Pfam PF00155 Aminotransferase class I and II 39 386 1.6E-40 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MC49_RS19130 d4af327c7afbe36c2a9ac13b992e70ce 390 SUPERFAMILY SSF53383 1 389 5.85E-92 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS19130 d4af327c7afbe36c2a9ac13b992e70ce 390 Gene3D G3DSA:3.40.640.10 47 279 1.5E-36 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS19130 d4af327c7afbe36c2a9ac13b992e70ce 390 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 4 389 5.9E-108 T 29-03-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 MC49_RS19130 d4af327c7afbe36c2a9ac13b992e70ce 390 Gene3D G3DSA:3.90.1150.10 280 389 9.1E-22 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS01430 69b30f33e7da6d2d1a91fc8ab62cf290 777 SUPERFAMILY SSF55874 336 503 1.03E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS01430 69b30f33e7da6d2d1a91fc8ab62cf290 777 Gene3D G3DSA:3.30.450.20 101 279 1.4E-23 T 29-03-2018 MC49_RS01430 69b30f33e7da6d2d1a91fc8ab62cf290 777 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 153 275 1.6E-14 T 29-03-2018 IPR000014 PAS domain MC49_RS01430 69b30f33e7da6d2d1a91fc8ab62cf290 777 SMART SM00091 155 221 2.0E-4 T 29-03-2018 IPR000014 PAS domain MC49_RS01430 69b30f33e7da6d2d1a91fc8ab62cf290 777 Pfam PF00512 His Kinase A (phospho-acceptor) domain 283 345 1.3E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS01430 69b30f33e7da6d2d1a91fc8ab62cf290 777 SMART SM00387 394 507 1.8E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS01430 69b30f33e7da6d2d1a91fc8ab62cf290 777 Gene3D G3DSA:1.20.120.160 643 766 7.3E-16 T 29-03-2018 MC49_RS01430 69b30f33e7da6d2d1a91fc8ab62cf290 777 SMART SM00073 676 773 6.4E-9 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MC49_RS01430 69b30f33e7da6d2d1a91fc8ab62cf290 777 SUPERFAMILY SSF55785 140 267 3.84E-20 T 29-03-2018 IPR000014 PAS domain MC49_RS01430 69b30f33e7da6d2d1a91fc8ab62cf290 777 SUPERFAMILY SSF52172 524 642 5.12E-28 T 29-03-2018 IPR011006 CheY-like superfamily MC49_RS01430 69b30f33e7da6d2d1a91fc8ab62cf290 777 SMART SM00448 524 637 4.8E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS01430 69b30f33e7da6d2d1a91fc8ab62cf290 777 SMART SM00388 282 347 1.2E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS01430 69b30f33e7da6d2d1a91fc8ab62cf290 777 Pfam PF01627 Hpt domain 687 758 7.8E-11 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MC49_RS01430 69b30f33e7da6d2d1a91fc8ab62cf290 777 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 395 503 1.8E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS01430 69b30f33e7da6d2d1a91fc8ab62cf290 777 Gene3D G3DSA:1.10.287.970 3 88 9.6E-36 T 29-03-2018 IPR027460 Aerobic respiration control sensor protein ArcB, transmembrane domain MC49_RS01430 69b30f33e7da6d2d1a91fc8ab62cf290 777 Gene3D G3DSA:3.40.50.2300 522 642 4.6E-29 T 29-03-2018 MC49_RS01430 69b30f33e7da6d2d1a91fc8ab62cf290 777 Pfam PF00072 Response regulator receiver domain 526 637 6.0E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS01430 69b30f33e7da6d2d1a91fc8ab62cf290 777 Gene3D G3DSA:1.10.287.130 280 343 7.8E-17 T 29-03-2018 MC49_RS01430 69b30f33e7da6d2d1a91fc8ab62cf290 777 PRINTS PR00344 Bacterial sensor protein C-terminal signature 491 504 1.9E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS01430 69b30f33e7da6d2d1a91fc8ab62cf290 777 PRINTS PR00344 Bacterial sensor protein C-terminal signature 467 485 1.9E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS01430 69b30f33e7da6d2d1a91fc8ab62cf290 777 PRINTS PR00344 Bacterial sensor protein C-terminal signature 431 445 1.9E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS01430 69b30f33e7da6d2d1a91fc8ab62cf290 777 PRINTS PR00344 Bacterial sensor protein C-terminal signature 449 459 1.9E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS01430 69b30f33e7da6d2d1a91fc8ab62cf290 777 SUPERFAMILY SSF47384 269 347 1.35E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS01430 69b30f33e7da6d2d1a91fc8ab62cf290 777 Pfam PF08448 PAS fold 161 271 1.4E-14 T 29-03-2018 IPR013656 PAS fold-4 MC49_RS01430 69b30f33e7da6d2d1a91fc8ab62cf290 777 Gene3D G3DSA:3.30.565.10 351 517 1.1E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS01430 69b30f33e7da6d2d1a91fc8ab62cf290 777 PIRSF PIRSF003182 1 777 0.0 T 29-03-2018 IPR014409 Signal transduction histidine kinase, hybrid-type, aerobic respiration control ArcB GO:0000155|GO:0000160|GO:0004673|GO:0016021 MC49_RS01430 69b30f33e7da6d2d1a91fc8ab62cf290 777 SUPERFAMILY SSF47226 665 774 6.15E-26 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MC49_RS01435 dd96cfe2d50f26454d14500e021ba2cc 1485 Pfam PF00310 Glutamine amidotransferases class-II 12 424 4.0E-170 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain MC49_RS01435 dd96cfe2d50f26454d14500e021ba2cc 1485 SUPERFAMILY SSF56235 12 428 4.0E-147 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MC49_RS01435 dd96cfe2d50f26454d14500e021ba2cc 1485 Gene3D G3DSA:3.60.20.10 12 435 3.9E-141 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MC49_RS01435 dd96cfe2d50f26454d14500e021ba2cc 1485 Pfam PF04898 Glutamate synthase central domain 457 736 4.5E-102 T 29-03-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 MC49_RS01435 dd96cfe2d50f26454d14500e021ba2cc 1485 Gene3D G3DSA:2.160.20.60 1210 1479 5.4E-92 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 MC49_RS01435 dd96cfe2d50f26454d14500e021ba2cc 1485 Gene3D G3DSA:3.20.20.70 777 1205 1.2E-147 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS01435 dd96cfe2d50f26454d14500e021ba2cc 1485 Pfam PF01493 GXGXG motif 1234 1416 1.6E-73 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 MC49_RS01435 dd96cfe2d50f26454d14500e021ba2cc 1485 SUPERFAMILY SSF69336 1211 1464 3.79E-83 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 MC49_RS01435 dd96cfe2d50f26454d14500e021ba2cc 1485 SUPERFAMILY SSF51395 431 1188 2.85E-252 T 29-03-2018 MC49_RS01435 dd96cfe2d50f26454d14500e021ba2cc 1485 Gene3D G3DSA:3.20.20.70 436 776 1.4E-82 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS01435 dd96cfe2d50f26454d14500e021ba2cc 1485 Pfam PF01645 Conserved region in glutamate synthase 792 1156 2.6E-155 T 29-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 MC49_RS08700 a52fdc84bb1c74527effaed718e0f754 1036 Gene3D G3DSA:3.20.20.70 44 413 2.2E-10 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS08700 a52fdc84bb1c74527effaed718e0f754 1036 SUPERFAMILY SSF46548 454 564 3.19E-18 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MC49_RS08700 a52fdc84bb1c74527effaed718e0f754 1036 Gene3D G3DSA:3.50.50.60 695 860 2.4E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS08700 a52fdc84bb1c74527effaed718e0f754 1036 Gene3D G3DSA:3.50.50.60 647 694 1.0E-12 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS08700 a52fdc84bb1c74527effaed718e0f754 1036 TIGRFAM TIGR03315 Se_ygfK: putative selenate reductase, YgfK subunit 2 1031 0.0 T 29-03-2018 IPR017701 Putative selenate reductase YgfK MC49_RS08700 a52fdc84bb1c74527effaed718e0f754 1036 Gene3D G3DSA:1.10.1060.10 416 553 3.2E-24 T 29-03-2018 MC49_RS08700 a52fdc84bb1c74527effaed718e0f754 1036 Gene3D G3DSA:1.10.1060.10 870 966 1.6E-11 T 29-03-2018 MC49_RS08700 a52fdc84bb1c74527effaed718e0f754 1036 SUPERFAMILY SSF51395 46 139 7.79E-13 T 29-03-2018 MC49_RS08700 a52fdc84bb1c74527effaed718e0f754 1036 SUPERFAMILY SSF51395 205 260 7.79E-13 T 29-03-2018 MC49_RS08700 a52fdc84bb1c74527effaed718e0f754 1036 SUPERFAMILY SSF51395 290 408 7.79E-13 T 29-03-2018 MC49_RS08700 a52fdc84bb1c74527effaed718e0f754 1036 SUPERFAMILY SSF46548 887 969 1.88E-10 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MC49_RS08700 a52fdc84bb1c74527effaed718e0f754 1036 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 942 953 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MC49_RS08700 a52fdc84bb1c74527effaed718e0f754 1036 Gene3D G3DSA:3.40.50.720 554 646 6.0E-15 T 29-03-2018 MC49_RS08700 a52fdc84bb1c74527effaed718e0f754 1036 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 457 536 2.9E-16 T 29-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 MC49_RS08700 a52fdc84bb1c74527effaed718e0f754 1036 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 556 843 8.7E-40 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS08700 a52fdc84bb1c74527effaed718e0f754 1036 PRINTS PR00419 Adrenodoxin reductase family signature 578 591 5.0E-16 T 29-03-2018 MC49_RS08700 a52fdc84bb1c74527effaed718e0f754 1036 PRINTS PR00419 Adrenodoxin reductase family signature 555 577 5.0E-16 T 29-03-2018 MC49_RS08700 a52fdc84bb1c74527effaed718e0f754 1036 PRINTS PR00419 Adrenodoxin reductase family signature 684 698 5.0E-16 T 29-03-2018 MC49_RS08700 a52fdc84bb1c74527effaed718e0f754 1036 SUPERFAMILY SSF51971 555 789 8.83E-48 T 29-03-2018 MC49_RS01620 63f2bcb3eac69bb305d5e9a7f3faf71b 365 Gene3D G3DSA:3.40.50.1980 18 156 2.8E-23 T 29-03-2018 MC49_RS01620 63f2bcb3eac69bb305d5e9a7f3faf71b 365 Pfam PF01497 Periplasmic binding protein 77 307 6.2E-26 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 MC49_RS01620 63f2bcb3eac69bb305d5e9a7f3faf71b 365 SUPERFAMILY SSF53807 23 356 1.57E-49 T 29-03-2018 MC49_RS01620 63f2bcb3eac69bb305d5e9a7f3faf71b 365 Gene3D G3DSA:3.40.50.1980 157 341 1.6E-37 T 29-03-2018 MC49_RS13210 c25fdab5e33fd6433656a07a7133356d 70 SMART SM00357 6 70 1.7E-29 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 MC49_RS13210 c25fdab5e33fd6433656a07a7133356d 70 SUPERFAMILY SSF50249 3 68 7.24E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS13210 c25fdab5e33fd6433656a07a7133356d 70 Pfam PF00313 'Cold-shock' DNA-binding domain 5 69 9.9E-32 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MC49_RS13210 c25fdab5e33fd6433656a07a7133356d 70 Gene3D G3DSA:2.40.50.140 1 70 6.6E-27 T 29-03-2018 MC49_RS13210 c25fdab5e33fd6433656a07a7133356d 70 PIRSF PIRSF002599 1 70 1.4E-24 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 MC49_RS13210 c25fdab5e33fd6433656a07a7133356d 70 PRINTS PR00050 Cold shock protein signature 7 22 4.7E-17 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MC49_RS13210 c25fdab5e33fd6433656a07a7133356d 70 PRINTS PR00050 Cold shock protein signature 28 37 4.7E-17 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MC49_RS13210 c25fdab5e33fd6433656a07a7133356d 70 PRINTS PR00050 Cold shock protein signature 43 61 4.7E-17 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MC49_RS13210 c25fdab5e33fd6433656a07a7133356d 70 ProSitePatterns PS00352 'Cold-shock' domain signature. 18 37 - T 29-03-2018 IPR019844 Cold-shock conserved site MC49_RS13005 c25fdab5e33fd6433656a07a7133356d 70 SMART SM00357 6 70 1.7E-29 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 MC49_RS13005 c25fdab5e33fd6433656a07a7133356d 70 SUPERFAMILY SSF50249 3 68 7.24E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS13005 c25fdab5e33fd6433656a07a7133356d 70 Pfam PF00313 'Cold-shock' DNA-binding domain 5 69 9.9E-32 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MC49_RS13005 c25fdab5e33fd6433656a07a7133356d 70 Gene3D G3DSA:2.40.50.140 1 70 6.6E-27 T 29-03-2018 MC49_RS13005 c25fdab5e33fd6433656a07a7133356d 70 PIRSF PIRSF002599 1 70 1.4E-24 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 MC49_RS13005 c25fdab5e33fd6433656a07a7133356d 70 PRINTS PR00050 Cold shock protein signature 7 22 4.7E-17 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MC49_RS13005 c25fdab5e33fd6433656a07a7133356d 70 PRINTS PR00050 Cold shock protein signature 28 37 4.7E-17 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MC49_RS13005 c25fdab5e33fd6433656a07a7133356d 70 PRINTS PR00050 Cold shock protein signature 43 61 4.7E-17 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MC49_RS13005 c25fdab5e33fd6433656a07a7133356d 70 ProSitePatterns PS00352 'Cold-shock' domain signature. 18 37 - T 29-03-2018 IPR019844 Cold-shock conserved site MC49_RS05375 2d6e3255d9d80332bb72793fedf88843 197 Gene3D G3DSA:1.10.357.10 61 195 2.0E-20 T 29-03-2018 MC49_RS05375 2d6e3255d9d80332bb72793fedf88843 197 Gene3D G3DSA:1.10.10.60 2 60 1.2E-12 T 29-03-2018 MC49_RS05375 2d6e3255d9d80332bb72793fedf88843 197 SUPERFAMILY SSF46689 8 88 2.72E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS05375 2d6e3255d9d80332bb72793fedf88843 197 SUPERFAMILY SSF48498 84 194 1.72E-8 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MC49_RS05375 2d6e3255d9d80332bb72793fedf88843 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 60 2.2E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS05375 2d6e3255d9d80332bb72793fedf88843 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.3E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS05375 2d6e3255d9d80332bb72793fedf88843 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.3E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS04520 6a5f78ea2cbb8824b86ab3ce00368bf6 216 Pfam PF01144 Coenzyme A transferase 8 212 1.0E-68 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 MC49_RS04520 6a5f78ea2cbb8824b86ab3ce00368bf6 216 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 17 32 - T 29-03-2018 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 Reactome: R-HSA-77108 MC49_RS04520 6a5f78ea2cbb8824b86ab3ce00368bf6 216 SMART SM00882 5 216 1.7E-67 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 MC49_RS04520 6a5f78ea2cbb8824b86ab3ce00368bf6 216 Gene3D G3DSA:3.40.1080.10 1 215 6.7E-73 T 29-03-2018 MC49_RS04520 6a5f78ea2cbb8824b86ab3ce00368bf6 216 SUPERFAMILY SSF100950 2 214 3.27E-75 T 29-03-2018 MC49_RS04520 6a5f78ea2cbb8824b86ab3ce00368bf6 216 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 7 214 6.4E-67 T 29-03-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 MC49_RS18465 a8220d02185e9b16c76bddf3bfecd8a0 193 Hamap MF_00346 UPF0149 protein YgfB [ygfB]. 6 191 30.677 T 29-03-2018 IPR011978 Uncharacterised protein family UPF0149 MC49_RS18465 a8220d02185e9b16c76bddf3bfecd8a0 193 Pfam PF03695 Uncharacterised protein family (UPF0149) 12 173 2.2E-37 T 29-03-2018 IPR011978 Uncharacterised protein family UPF0149 MC49_RS18465 a8220d02185e9b16c76bddf3bfecd8a0 193 SUPERFAMILY SSF101327 8 172 2.22E-47 T 29-03-2018 IPR011978 Uncharacterised protein family UPF0149 MC49_RS18465 a8220d02185e9b16c76bddf3bfecd8a0 193 TIGRFAM TIGR02292 ygfB_yecA: yecA family protein 13 164 8.3E-12 T 29-03-2018 IPR011978 Uncharacterised protein family UPF0149 MC49_RS16390 0b5235130382bc98097841e3da8c3f2b 275 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 43 179 3.1E-21 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MC49_RS16390 0b5235130382bc98097841e3da8c3f2b 275 Pfam PF01471 Putative peptidoglycan binding domain 215 265 1.1E-11 T 29-03-2018 IPR002477 Peptidoglycan binding-like MC49_RS16390 0b5235130382bc98097841e3da8c3f2b 275 SUPERFAMILY SSF55846 27 194 2.49E-44 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MC49_RS16390 0b5235130382bc98097841e3da8c3f2b 275 Gene3D G3DSA:3.40.80.10 43 192 5.5E-38 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MC49_RS16390 0b5235130382bc98097841e3da8c3f2b 275 SMART SM00644 35 178 4.6E-14 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MC49_RS16390 0b5235130382bc98097841e3da8c3f2b 275 Gene3D G3DSA:1.10.101.10 193 275 5.4E-16 T 29-03-2018 IPR002477 Peptidoglycan binding-like MC49_RS16390 0b5235130382bc98097841e3da8c3f2b 275 SUPERFAMILY SSF47090 199 274 6.87E-21 T 29-03-2018 IPR002477 Peptidoglycan binding-like MC49_RS15945 95855bfe462897a9b8f5dd9dec9e1743 334 Hamap MF_01004 Vitamin B12 import system permease protein BtuC [btuC]. 5 331 29.495 T 29-03-2018 IPR023691 ABC transporter, vitamin B12 import, permease protein BtuC GO:0015889|GO:0016020 MC49_RS15945 95855bfe462897a9b8f5dd9dec9e1743 334 Pfam PF01032 FecCD transport family 27 328 2.4E-86 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 MC49_RS15945 95855bfe462897a9b8f5dd9dec9e1743 334 SUPERFAMILY SSF81345 10 328 3.53E-83 T 29-03-2018 IPR029022 ABC transporter, BtuC-like MC49_RS15945 95855bfe462897a9b8f5dd9dec9e1743 334 Gene3D G3DSA:1.10.3470.10 11 333 5.3E-62 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like MC49_RS04445 34a2e339aebac7f2ef1728563381cb54 303 Gene3D G3DSA:1.10.1670.10 250 301 3.7E-9 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 MC49_RS04445 34a2e339aebac7f2ef1728563381cb54 303 SUPERFAMILY SSF48150 117 298 1.34E-33 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 MC49_RS04445 34a2e339aebac7f2ef1728563381cb54 303 Gene3D G3DSA:1.10.340.30 126 246 6.8E-18 T 29-03-2018 MC49_RS04445 34a2e339aebac7f2ef1728563381cb54 303 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 135 280 1.4E-10 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MC49_RS04445 34a2e339aebac7f2ef1728563381cb54 303 SMART SM00478 137 299 5.7E-8 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MC49_RS04445 34a2e339aebac7f2ef1728563381cb54 303 Gene3D G3DSA:3.30.310.20 8 125 5.8E-15 T 29-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal MC49_RS04445 34a2e339aebac7f2ef1728563381cb54 303 SMART SM01009 8 127 8.5E-5 T 29-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal MC49_RS12225 6fdc7e68696c0e804e7c63e74dbf99d4 143 Pfam PF00583 Acetyltransferase (GNAT) family 15 122 1.1E-13 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MC49_RS12225 6fdc7e68696c0e804e7c63e74dbf99d4 143 Gene3D G3DSA:3.40.630.30 1 140 1.9E-28 T 29-03-2018 MC49_RS12225 6fdc7e68696c0e804e7c63e74dbf99d4 143 SUPERFAMILY SSF55729 1 128 1.99E-27 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS02115 edc9c8b7c6d8299aa57104dfef49ba8b 246 Gene3D G3DSA:3.40.50.10490 73 245 1.5E-26 T 29-03-2018 MC49_RS02115 edc9c8b7c6d8299aa57104dfef49ba8b 246 SUPERFAMILY SSF46689 6 73 3.76E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS02115 edc9c8b7c6d8299aa57104dfef49ba8b 246 Pfam PF01418 Helix-turn-helix domain, rpiR family 7 70 1.2E-12 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 MC49_RS02115 edc9c8b7c6d8299aa57104dfef49ba8b 246 Pfam PF01380 SIS domain 112 211 3.1E-15 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MC49_RS02115 edc9c8b7c6d8299aa57104dfef49ba8b 246 SUPERFAMILY SSF53697 88 242 1.57E-28 T 29-03-2018 MC49_RS02115 edc9c8b7c6d8299aa57104dfef49ba8b 246 Gene3D G3DSA:1.10.10.10 3 72 1.1E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS08050 6ea8c073d80979fdca9a547c6dbf9a5f 398 SUPERFAMILY SSF55347 126 274 2.55E-59 T 29-03-2018 MC49_RS08050 6ea8c073d80979fdca9a547c6dbf9a5f 398 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 392 45.77 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 MC49_RS08050 6ea8c073d80979fdca9a547c6dbf9a5f 398 SUPERFAMILY SSF51735 2 150 2.42E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS08050 6ea8c073d80979fdca9a547c6dbf9a5f 398 SUPERFAMILY SSF69055 302 395 2.35E-30 T 29-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 MC49_RS08050 6ea8c073d80979fdca9a547c6dbf9a5f 398 Gene3D G3DSA:3.40.50.720 1 150 7.1E-47 T 29-03-2018 MC49_RS08050 6ea8c073d80979fdca9a547c6dbf9a5f 398 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1 396 7.4E-170 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 MC49_RS08050 6ea8c073d80979fdca9a547c6dbf9a5f 398 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 132 4.4E-45 T 29-03-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 MC49_RS08050 6ea8c073d80979fdca9a547c6dbf9a5f 398 PIRSF PIRSF006205 1 398 1.6E-150 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 MC49_RS08050 6ea8c073d80979fdca9a547c6dbf9a5f 398 Pfam PF13288 DXP reductoisomerase C-terminal domain 271 387 1.6E-41 T 29-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 MC49_RS08050 6ea8c073d80979fdca9a547c6dbf9a5f 398 Gene3D G3DSA:1.10.1740.10 312 396 6.6E-30 T 29-03-2018 MC49_RS08050 6ea8c073d80979fdca9a547c6dbf9a5f 398 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 146 239 1.4E-35 T 29-03-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 MC49_RS14375 ea236cba29bd4d2e7782e2e9d00e355f 509 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 368 1.2E-73 T 29-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain MC49_RS14375 ea236cba29bd4d2e7782e2e9d00e355f 509 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 426 508 8.2E-35 T 29-03-2018 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 MC49_RS14375 ea236cba29bd4d2e7782e2e9d00e355f 509 SUPERFAMILY SSF52283 1 168 1.19E-55 T 29-03-2018 MC49_RS14375 ea236cba29bd4d2e7782e2e9d00e355f 509 Gene3D G3DSA:3.40.50.720 206 377 5.4E-58 T 29-03-2018 MC49_RS14375 ea236cba29bd4d2e7782e2e9d00e355f 509 Gene3D G3DSA:3.40.50.720 1 153 7.4E-49 T 29-03-2018 MC49_RS14375 ea236cba29bd4d2e7782e2e9d00e355f 509 SUPERFAMILY SSF51735 137 301 1.69E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS14375 ea236cba29bd4d2e7782e2e9d00e355f 509 Gene3D G3DSA:3.40.50.10730 154 205 2.2E-4 T 29-03-2018 MC49_RS14375 ea236cba29bd4d2e7782e2e9d00e355f 509 SMART SM01003 4 137 2.0E-72 T 29-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal MC49_RS14375 ea236cba29bd4d2e7782e2e9d00e355f 509 PIRSF PIRSF000203 1 508 3.7E-276 T 29-03-2018 IPR026255 NAD(P) transhydrogenase, alpha subunit GO:0008746|GO:0015992|GO:0055114 KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 MC49_RS14375 ea236cba29bd4d2e7782e2e9d00e355f 509 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 170 195 - T 29-03-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 Reactome: R-HSA-71403 MC49_RS14375 ea236cba29bd4d2e7782e2e9d00e355f 509 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 1.1E-50 T 29-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal MC49_RS14375 ea236cba29bd4d2e7782e2e9d00e355f 509 SMART SM01002 146 311 4.0E-84 T 29-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain MC49_RS14375 ea236cba29bd4d2e7782e2e9d00e355f 509 TIGRFAM TIGR00561 pntA: NAD(P)(+) transhydrogenase (AB-specific), alpha subunit 2 509 1.2E-287 T 29-03-2018 IPR026255 NAD(P) transhydrogenase, alpha subunit GO:0008746|GO:0015992|GO:0055114 KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 MC49_RS12155 d7b5e96f84d6110615cccd4958a48d7d 1674 Gene3D G3DSA:2.60.40.10 777 866 0.2 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS12155 d7b5e96f84d6110615cccd4958a48d7d 1674 Pfam PF01835 MG2 domain 406 496 6.0E-16 T 29-03-2018 IPR002890 Alpha-2-macroglobulin, N-terminal GO:0004866 MC49_RS12155 d7b5e96f84d6110615cccd4958a48d7d 1674 SMART SM01359 778 927 3.7E-35 T 29-03-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 MC49_RS12155 d7b5e96f84d6110615cccd4958a48d7d 1674 Pfam PF10569 Alpha-macro-globulin thiol-ester bond-forming region 1204 1222 8.4E-5 T 29-03-2018 IPR019565 Alpha-2-macroglobulin, thiol-ester bond-forming MC49_RS12155 d7b5e96f84d6110615cccd4958a48d7d 1674 SMART SM01360 994 1079 6.1E-18 T 29-03-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 MC49_RS12155 d7b5e96f84d6110615cccd4958a48d7d 1674 Gene3D G3DSA:2.60.40.10 400 499 4.2E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS12155 d7b5e96f84d6110615cccd4958a48d7d 1674 Gene3D G3DSA:2.60.40.10 871 1041 0.036 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS12155 d7b5e96f84d6110615cccd4958a48d7d 1674 Pfam PF00207 Alpha-2-macroglobulin family 997 1078 2.9E-7 T 29-03-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 MC49_RS12155 d7b5e96f84d6110615cccd4958a48d7d 1674 Gene3D G3DSA:2.60.40.10 1042 1143 8.6E-6 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS12155 d7b5e96f84d6110615cccd4958a48d7d 1674 Pfam PF07703 Alpha-2-macroglobulin family N-terminal region 779 927 6.0E-13 T 29-03-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 MC49_RS12155 d7b5e96f84d6110615cccd4958a48d7d 1674 Gene3D G3DSA:2.60.40.10 320 377 0.032 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS12155 d7b5e96f84d6110615cccd4958a48d7d 1674 Gene3D G3DSA:1.50.10.20 1191 1490 2.9E-24 T 29-03-2018 MC49_RS12155 d7b5e96f84d6110615cccd4958a48d7d 1674 Pfam PF11974 Alpha-2-macroglobulin MG1 domain 307 400 1.2E-22 T 29-03-2018 MC49_RS12155 d7b5e96f84d6110615cccd4958a48d7d 1674 SUPERFAMILY SSF48239 1199 1453 6.95E-38 T 29-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid MC49_RS12155 d7b5e96f84d6110615cccd4958a48d7d 1674 PIRSF PIRSF038980 12 1674 0.0 T 29-03-2018 IPR026284 Alpha-2-macroglobulin domain protein, bacteria MC49_RS12155 d7b5e96f84d6110615cccd4958a48d7d 1674 Gene3D G3DSA:3.40.1000.10 34 129 0.0021 T 29-03-2018 MC49_RS03840 92732e5925844e47580337df917d5451 419 SUPERFAMILY SSF50249 48 125 9.0E-30 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS03840 92732e5925844e47580337df917d5451 419 Pfam PF07498 Rho termination factor, N-terminal domain 5 47 2.0E-16 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 MC49_RS03840 92732e5925844e47580337df917d5451 419 SUPERFAMILY SSF52540 90 371 4.24E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS03840 92732e5925844e47580337df917d5451 419 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 419 250.18 T 29-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 MC49_RS03840 92732e5925844e47580337df917d5451 419 Pfam PF07497 Rho termination factor, RNA-binding domain 52 125 3.1E-32 T 29-03-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 MC49_RS03840 92732e5925844e47580337df917d5451 419 SMART SM00357 52 118 9.6E-19 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 MC49_RS03840 92732e5925844e47580337df917d5451 419 Gene3D G3DSA:2.40.50.140 2 126 2.3E-46 T 29-03-2018 MC49_RS03840 92732e5925844e47580337df917d5451 419 SMART SM00382 170 355 4.8E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS03840 92732e5925844e47580337df917d5451 419 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 160 363 3.2E-23 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MC49_RS03840 92732e5925844e47580337df917d5451 419 SUPERFAMILY SSF68912 1 46 3.92E-12 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 MC49_RS03840 92732e5925844e47580337df917d5451 419 TIGRFAM TIGR00767 rho: transcription termination factor Rho 2 417 3.9E-221 T 29-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 MC49_RS03840 92732e5925844e47580337df917d5451 419 SMART SM00959 5 47 3.1E-17 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 MC49_RS03840 92732e5925844e47580337df917d5451 419 Gene3D G3DSA:3.40.50.300 129 419 1.9E-58 T 29-03-2018 MC49_RS10360 c297ee7aafcacd8e17ec8a00e3b63fd9 119 SUPERFAMILY SSF81343 10 119 5.45E-26 T 29-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MC49_RS10360 c297ee7aafcacd8e17ec8a00e3b63fd9 119 PIRSF PIRSF000169 1 119 4.2E-39 T 29-03-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 MC49_RS10360 c297ee7aafcacd8e17ec8a00e3b63fd9 119 TIGRFAM TIGR02968 succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein 14 117 2.5E-34 T 29-03-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 MC49_RS10360 c297ee7aafcacd8e17ec8a00e3b63fd9 119 Gene3D G3DSA:1.20.1300.10 5 119 9.8E-16 T 29-03-2018 MC49_RS09790 206818388253d5dd727079ad3fc5b9f7 177 SUPERFAMILY SSF52540 8 174 2.42E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS09790 206818388253d5dd727079ad3fc5b9f7 177 Gene3D G3DSA:3.40.50.300 7 177 1.6E-27 T 29-03-2018 MC49_RS09790 206818388253d5dd727079ad3fc5b9f7 177 Hamap MF_00109 Shikimate kinase [aroK]. 7 174 24.649 T 29-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 MC49_RS09790 206818388253d5dd727079ad3fc5b9f7 177 PRINTS PR01100 Shikimate kinase family signature 79 88 2.0E-24 T 29-03-2018 MC49_RS09790 206818388253d5dd727079ad3fc5b9f7 177 PRINTS PR01100 Shikimate kinase family signature 100 117 2.0E-24 T 29-03-2018 MC49_RS09790 206818388253d5dd727079ad3fc5b9f7 177 PRINTS PR01100 Shikimate kinase family signature 10 25 2.0E-24 T 29-03-2018 MC49_RS09790 206818388253d5dd727079ad3fc5b9f7 177 PRINTS PR01100 Shikimate kinase family signature 34 47 2.0E-24 T 29-03-2018 MC49_RS09790 206818388253d5dd727079ad3fc5b9f7 177 PRINTS PR01100 Shikimate kinase family signature 62 70 2.0E-24 T 29-03-2018 MC49_RS09790 206818388253d5dd727079ad3fc5b9f7 177 ProSitePatterns PS01128 Shikimate kinase signature. 63 87 - T 29-03-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 MC49_RS09790 206818388253d5dd727079ad3fc5b9f7 177 Pfam PF01202 Shikimate kinase 16 170 1.1E-43 T 29-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 MC49_RS00715 ecd2d9a66d67984f71bab44b1e0eb977 232 Pfam PF06508 Queuosine biosynthesis protein QueC 3 214 2.1E-82 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 MC49_RS00715 ecd2d9a66d67984f71bab44b1e0eb977 232 PIRSF PIRSF006293 1 227 1.2E-84 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 MC49_RS00715 ecd2d9a66d67984f71bab44b1e0eb977 232 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 4 207 1.1E-84 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 MC49_RS00715 ecd2d9a66d67984f71bab44b1e0eb977 232 SUPERFAMILY SSF52402 1 215 6.17E-66 T 29-03-2018 MC49_RS00715 ecd2d9a66d67984f71bab44b1e0eb977 232 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 2 220 50.024 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 MC49_RS00715 ecd2d9a66d67984f71bab44b1e0eb977 232 Gene3D G3DSA:3.40.50.620 1 232 2.3E-52 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS08580 94110a1d015ba95e121ed691e7239005 478 Gene3D G3DSA:3.40.605.10 55 266 2.0E-27 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MC49_RS08580 94110a1d015ba95e121ed691e7239005 478 Gene3D G3DSA:3.40.50.261 4 54 0.076 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MC49_RS08580 94110a1d015ba95e121ed691e7239005 478 Pfam PF00171 Aldehyde dehydrogenase family 45 432 3.0E-28 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MC49_RS08580 94110a1d015ba95e121ed691e7239005 478 SUPERFAMILY SSF53720 45 450 4.58E-61 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MC49_RS08580 94110a1d015ba95e121ed691e7239005 478 PIRSF PIRSF036410 1 478 6.1E-207 T 29-03-2018 IPR012408 Acetaldehyde/propionaldehyde dehydrogenase, EutE/PduP-related MC49_RS08580 94110a1d015ba95e121ed691e7239005 478 Gene3D G3DSA:3.40.309.10 267 437 1.3E-25 T 29-03-2018 MC49_RS16400 1276dcba50a50de03330890423461b1b 216 SUPERFAMILY SSF51161 39 200 8.73E-44 T 29-03-2018 IPR011004 Trimeric LpxA-like MC49_RS16400 1276dcba50a50de03330890423461b1b 216 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 118 146 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MC49_RS16400 1276dcba50a50de03330890423461b1b 216 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 109 142 2.3E-11 T 29-03-2018 IPR001451 Hexapeptide repeat MC49_RS16400 1276dcba50a50de03330890423461b1b 216 Gene3D G3DSA:2.160.10.10 1 210 1.4E-40 T 29-03-2018 MC49_RS06395 40c5fde5fec5515cdcfe2be9229568ee 125 Gene3D G3DSA:1.20.5.1030 68 119 7.4E-19 T 29-03-2018 MC49_RS06395 40c5fde5fec5515cdcfe2be9229568ee 125 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 70 122 4.0E-20 T 29-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MC49_RS06395 40c5fde5fec5515cdcfe2be9229568ee 125 Hamap MF_00422 Protein translocase subunit SecE [secE]. 63 121 13.16 T 29-03-2018 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MC49_RS06395 40c5fde5fec5515cdcfe2be9229568ee 125 PRINTS PR01650 Bacterial translocase SecE signature 44 65 2.0E-37 T 29-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 MC49_RS06395 40c5fde5fec5515cdcfe2be9229568ee 125 PRINTS PR01650 Bacterial translocase SecE signature 89 109 2.0E-37 T 29-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 MC49_RS06395 40c5fde5fec5515cdcfe2be9229568ee 125 PRINTS PR01650 Bacterial translocase SecE signature 109 125 2.0E-37 T 29-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 MC49_RS06395 40c5fde5fec5515cdcfe2be9229568ee 125 PRINTS PR01650 Bacterial translocase SecE signature 65 85 2.0E-37 T 29-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 MC49_RS06395 40c5fde5fec5515cdcfe2be9229568ee 125 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 71 99 - T 29-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MC49_RS06395 40c5fde5fec5515cdcfe2be9229568ee 125 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 70 122 1.2E-16 T 29-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 MC49_RS02985 0c4eaa62e7eafef9e0a2038a0fb90a5c 495 SMART SM00345 23 82 9.2E-16 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MC49_RS02985 0c4eaa62e7eafef9e0a2038a0fb90a5c 495 SUPERFAMILY SSF46785 19 85 3.4E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS02985 0c4eaa62e7eafef9e0a2038a0fb90a5c 495 Gene3D G3DSA:3.90.1150.10 394 491 2.1E-20 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS02985 0c4eaa62e7eafef9e0a2038a0fb90a5c 495 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 82 5.7E-16 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MC49_RS02985 0c4eaa62e7eafef9e0a2038a0fb90a5c 495 Pfam PF00155 Aminotransferase class I and II 163 428 1.1E-18 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MC49_RS02985 0c4eaa62e7eafef9e0a2038a0fb90a5c 495 Gene3D G3DSA:3.40.640.10 151 393 6.1E-44 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS02985 0c4eaa62e7eafef9e0a2038a0fb90a5c 495 SUPERFAMILY SSF53383 125 488 3.38E-84 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS02985 0c4eaa62e7eafef9e0a2038a0fb90a5c 495 Gene3D G3DSA:1.10.10.10 17 84 2.8E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS04125 d282dfc807cd32f03e75da008782ca7f 136 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 58 69 - T 29-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS04125 d282dfc807cd32f03e75da008782ca7f 136 Pfam PF00252 Ribosomal protein L16p/L10e 4 131 8.8E-47 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 MC49_RS04125 d282dfc807cd32f03e75da008782ca7f 136 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 81 92 - T 29-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS04125 d282dfc807cd32f03e75da008782ca7f 136 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 133 38.236 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS04125 d282dfc807cd32f03e75da008782ca7f 136 Gene3D G3DSA:3.90.1170.10 1 136 1.0E-50 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 MC49_RS04125 d282dfc807cd32f03e75da008782ca7f 136 PRINTS PR00060 Ribosomal protein L16 signature 23 35 2.2E-40 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS04125 d282dfc807cd32f03e75da008782ca7f 136 PRINTS PR00060 Ribosomal protein L16 signature 57 86 2.2E-40 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS04125 d282dfc807cd32f03e75da008782ca7f 136 PRINTS PR00060 Ribosomal protein L16 signature 87 116 2.2E-40 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS04125 d282dfc807cd32f03e75da008782ca7f 136 PRINTS PR00060 Ribosomal protein L16 signature 41 52 2.2E-40 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS04125 d282dfc807cd32f03e75da008782ca7f 136 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 126 4.2E-59 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS04125 d282dfc807cd32f03e75da008782ca7f 136 SUPERFAMILY SSF54686 3 133 6.67E-55 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 MC49_RS11230 b6cac225277d62d5a58304893dfb4f4e 466 SUPERFAMILY SSF50249 16 101 1.62E-17 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS11230 b6cac225277d62d5a58304893dfb4f4e 466 Pfam PF01336 OB-fold nucleic acid binding domain 20 99 3.3E-11 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 MC49_RS11230 b6cac225277d62d5a58304893dfb4f4e 466 PRINTS PR01042 Aspartyl-tRNA synthetase signature 421 435 2.7E-14 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS11230 b6cac225277d62d5a58304893dfb4f4e 466 PRINTS PR01042 Aspartyl-tRNA synthetase signature 381 397 2.7E-14 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS11230 b6cac225277d62d5a58304893dfb4f4e 466 PRINTS PR01042 Aspartyl-tRNA synthetase signature 208 220 2.7E-14 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS11230 b6cac225277d62d5a58304893dfb4f4e 466 PRINTS PR01042 Aspartyl-tRNA synthetase signature 224 237 2.7E-14 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS11230 b6cac225277d62d5a58304893dfb4f4e 466 SUPERFAMILY SSF55681 104 464 2.79E-95 T 29-03-2018 MC49_RS11230 b6cac225277d62d5a58304893dfb4f4e 466 Gene3D G3DSA:3.30.930.10 128 462 2.7E-95 T 29-03-2018 MC49_RS11230 b6cac225277d62d5a58304893dfb4f4e 466 Pfam PF00152 tRNA synthetases class II (D, K and N) 118 460 1.9E-83 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS11230 b6cac225277d62d5a58304893dfb4f4e 466 Gene3D G3DSA:2.40.50.140 7 109 5.1E-18 T 29-03-2018 MC49_RS11230 b6cac225277d62d5a58304893dfb4f4e 466 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 5 466 2.3E-205 T 29-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 MC49_RS11230 b6cac225277d62d5a58304893dfb4f4e 466 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 6 466 46.066 T 29-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 MC49_RS04620 4371d627877dbe69b246850a399d8421 551 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 179 204 - T 29-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 MC49_RS04620 4371d627877dbe69b246850a399d8421 551 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 64 468 1.5E-62 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 MC49_RS04620 4371d627877dbe69b246850a399d8421 551 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 452 472 - T 29-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 MC49_RS04620 4371d627877dbe69b246850a399d8421 551 Pfam PF00474 Sodium:solute symporter family 64 470 1.1E-123 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 MC49_RS03225 90069aab5ceb6a959f419edd8e651b84 965 SUPERFAMILY SSF50677 205 379 3.14E-59 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MC49_RS03225 90069aab5ceb6a959f419edd8e651b84 965 Gene3D G3DSA:1.10.287.380 891 961 7.3E-23 T 29-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 MC49_RS03225 90069aab5ceb6a959f419edd8e651b84 965 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 900 957 3.6E-17 T 29-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 MC49_RS03225 90069aab5ceb6a959f419edd8e651b84 965 Hamap MF_02004 Valine--tRNA ligase [valS]. 15 963 16.21 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MC49_RS03225 90069aab5ceb6a959f419edd8e651b84 965 TIGRFAM TIGR00422 valS: valine--tRNA ligase 16 945 0.0 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MC49_RS03225 90069aab5ceb6a959f419edd8e651b84 965 SUPERFAMILY SSF46589 898 962 3.66E-15 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 MC49_RS03225 90069aab5ceb6a959f419edd8e651b84 965 PRINTS PR00986 Valyl-tRNA synthetase signature 250 267 6.4E-36 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MC49_RS03225 90069aab5ceb6a959f419edd8e651b84 965 PRINTS PR00986 Valyl-tRNA synthetase signature 483 504 6.4E-36 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MC49_RS03225 90069aab5ceb6a959f419edd8e651b84 965 PRINTS PR00986 Valyl-tRNA synthetase signature 514 532 6.4E-36 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MC49_RS03225 90069aab5ceb6a959f419edd8e651b84 965 PRINTS PR00986 Valyl-tRNA synthetase signature 383 396 6.4E-36 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MC49_RS03225 90069aab5ceb6a959f419edd8e651b84 965 PRINTS PR00986 Valyl-tRNA synthetase signature 49 60 6.4E-36 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MC49_RS03225 90069aab5ceb6a959f419edd8e651b84 965 SUPERFAMILY SSF52374 378 585 8.55E-137 T 29-03-2018 MC49_RS03225 90069aab5ceb6a959f419edd8e651b84 965 SUPERFAMILY SSF52374 14 206 8.55E-137 T 29-03-2018 MC49_RS03225 90069aab5ceb6a959f419edd8e651b84 965 SUPERFAMILY SSF52374 623 655 8.55E-137 T 29-03-2018 MC49_RS03225 90069aab5ceb6a959f419edd8e651b84 965 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 56 67 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS03225 90069aab5ceb6a959f419edd8e651b84 965 SUPERFAMILY SSF47323 656 912 3.36E-72 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS03225 90069aab5ceb6a959f419edd8e651b84 965 Pfam PF08264 Anticodon-binding domain of tRNA 688 839 3.4E-45 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 MC49_RS03225 90069aab5ceb6a959f419edd8e651b84 965 Gene3D G3DSA:3.40.50.620 299 561 1.0E-67 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS03225 90069aab5ceb6a959f419edd8e651b84 965 Gene3D G3DSA:3.40.50.620 36 215 1.3E-45 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS03225 90069aab5ceb6a959f419edd8e651b84 965 Gene3D G3DSA:3.90.740.10 216 258 5.0E-10 T 29-03-2018 MC49_RS03225 90069aab5ceb6a959f419edd8e651b84 965 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 28 645 6.8E-232 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS03225 90069aab5ceb6a959f419edd8e651b84 965 Gene3D G3DSA:1.10.730.10 562 831 1.4E-73 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS15660 b8d81b54be86fe5075ae95d1b5c189b6 216 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 176 216 2.3E-18 T 29-03-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MC49_RS15660 b8d81b54be86fe5075ae95d1b5c189b6 216 PIRSF PIRSF000190 1 216 8.5E-82 T 29-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MC49_RS15660 b8d81b54be86fe5075ae95d1b5c189b6 216 SUPERFAMILY SSF50475 19 216 6.79E-65 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MC49_RS15660 b8d81b54be86fe5075ae95d1b5c189b6 216 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 186 199 - T 29-03-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MC49_RS15660 b8d81b54be86fe5075ae95d1b5c189b6 216 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 3 216 8.4E-90 T 29-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MC49_RS15660 b8d81b54be86fe5075ae95d1b5c189b6 216 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 14 216 37.516 T 29-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MC49_RS15660 b8d81b54be86fe5075ae95d1b5c189b6 216 Gene3D G3DSA:2.30.110.10 15 216 4.2E-67 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MC49_RS15660 b8d81b54be86fe5075ae95d1b5c189b6 216 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 38 120 1.1E-21 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MC49_RS13835 cfa88fc910fe5ccd6f2ceaa7865a6ac0 544 TIGRFAM TIGR01315 5C_CHO_kinase: FGGY-family pentulose kinase 5 538 2.9E-217 T 29-03-2018 IPR006003 FGGY carbohydrate kinase, pentulose kinase GO:0005975|GO:0016773 MC49_RS13835 cfa88fc910fe5ccd6f2ceaa7865a6ac0 544 PIRSF PIRSF000538 2 543 4.8E-76 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MC49_RS13835 cfa88fc910fe5ccd6f2ceaa7865a6ac0 544 SUPERFAMILY SSF53067 4 263 4.94E-58 T 29-03-2018 MC49_RS13835 cfa88fc910fe5ccd6f2ceaa7865a6ac0 544 Gene3D G3DSA:3.30.420.40 277 544 2.1E-66 T 29-03-2018 MC49_RS13835 cfa88fc910fe5ccd6f2ceaa7865a6ac0 544 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 262 1.2E-26 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 MC49_RS13835 cfa88fc910fe5ccd6f2ceaa7865a6ac0 544 SUPERFAMILY SSF53067 280 533 2.2E-55 T 29-03-2018 MC49_RS13835 cfa88fc910fe5ccd6f2ceaa7865a6ac0 544 Gene3D G3DSA:3.30.420.40 1 263 2.1E-67 T 29-03-2018 MC49_RS13835 cfa88fc910fe5ccd6f2ceaa7865a6ac0 544 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 281 489 3.2E-45 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 MC49_RS12320 828703b2cee72831787218174fd1618c 507 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 153 165 - T 29-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 MC49_RS12320 828703b2cee72831787218174fd1618c 507 ProSitePatterns PS01022 PTR2 family proton/oligopeptide symporters signature 1. 77 101 - T 29-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 MC49_RS12320 828703b2cee72831787218174fd1618c 507 Gene3D G3DSA:1.20.1250.20 8 209 9.2E-26 T 29-03-2018 MC49_RS12320 828703b2cee72831787218174fd1618c 507 Gene3D G3DSA:1.20.1250.20 285 505 2.2E-14 T 29-03-2018 MC49_RS12320 828703b2cee72831787218174fd1618c 507 Pfam PF00854 POT family 89 458 2.6E-62 T 29-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 MC49_RS12320 828703b2cee72831787218174fd1618c 507 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 9 499 1.8E-109 T 29-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 MC49_RS12320 828703b2cee72831787218174fd1618c 507 SUPERFAMILY SSF103473 282 495 2.88E-32 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS12320 828703b2cee72831787218174fd1618c 507 SUPERFAMILY SSF103473 6 209 2.88E-32 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS08115 84834df1a0849589ab8eb8a931b9ccfa 460 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 13 312 23.151 T 29-03-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MC49_RS08115 84834df1a0849589ab8eb8a931b9ccfa 460 SUPERFAMILY SSF52402 15 235 2.46E-60 T 29-03-2018 MC49_RS08115 84834df1a0849589ab8eb8a931b9ccfa 460 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 371 416 6.2E-11 T 29-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MC49_RS08115 84834df1a0849589ab8eb8a931b9ccfa 460 Pfam PF11734 TilS substrate C-terminal domain 371 435 3.2E-23 T 29-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MC49_RS08115 84834df1a0849589ab8eb8a931b9ccfa 460 Gene3D G3DSA:3.40.50.620 15 228 5.0E-39 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS08115 84834df1a0849589ab8eb8a931b9ccfa 460 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 23 205 1.3E-50 T 29-03-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MC49_RS08115 84834df1a0849589ab8eb8a931b9ccfa 460 SUPERFAMILY SSF82829 240 321 2.88E-20 T 29-03-2018 MC49_RS08115 84834df1a0849589ab8eb8a931b9ccfa 460 SUPERFAMILY SSF56037 325 440 2.88E-26 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 MC49_RS08115 84834df1a0849589ab8eb8a931b9ccfa 460 Pfam PF09179 TilS substrate binding domain 250 317 6.9E-15 T 29-03-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MC49_RS08115 84834df1a0849589ab8eb8a931b9ccfa 460 Pfam PF01171 PP-loop family 23 201 1.1E-55 T 29-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 MC49_RS08115 84834df1a0849589ab8eb8a931b9ccfa 460 SMART SM00977 371 439 3.9E-18 T 29-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MC49_RS16980 5da80ad56de394e63516a4eb0d3aaca1 231 Gene3D G3DSA:2.60.40.10 149 226 2.6E-14 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS16980 5da80ad56de394e63516a4eb0d3aaca1 231 Gene3D G3DSA:2.60.40.10 30 148 1.3E-32 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS16980 5da80ad56de394e63516a4eb0d3aaca1 231 PRINTS PR00969 Pili chaperone signature 105 122 1.1E-28 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS16980 5da80ad56de394e63516a4eb0d3aaca1 231 PRINTS PR00969 Pili chaperone signature 129 144 1.1E-28 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS16980 5da80ad56de394e63516a4eb0d3aaca1 231 PRINTS PR00969 Pili chaperone signature 77 98 1.1E-28 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS16980 5da80ad56de394e63516a4eb0d3aaca1 231 PRINTS PR00969 Pili chaperone signature 161 176 1.1E-28 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS16980 5da80ad56de394e63516a4eb0d3aaca1 231 PRINTS PR00969 Pili chaperone signature 31 40 1.1E-28 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS16980 5da80ad56de394e63516a4eb0d3aaca1 231 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 168 223 2.2E-9 T 29-03-2018 IPR016148 Pili assembly chaperone, C-terminal MC49_RS16980 5da80ad56de394e63516a4eb0d3aaca1 231 SUPERFAMILY SSF49584 141 224 1.31E-17 T 29-03-2018 IPR016148 Pili assembly chaperone, C-terminal MC49_RS16980 5da80ad56de394e63516a4eb0d3aaca1 231 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 30 147 1.3E-37 T 29-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 MC49_RS16980 5da80ad56de394e63516a4eb0d3aaca1 231 SUPERFAMILY SSF49354 26 147 1.1E-35 T 29-03-2018 IPR008962 PapD-like MC49_RS18180 c231ac3b4a5ed0072034613d10ddd38c 329 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.3E-17 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MC49_RS18180 c231ac3b4a5ed0072034613d10ddd38c 329 SMART SM00354 1 76 3.7E-12 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MC49_RS18180 c231ac3b4a5ed0072034613d10ddd38c 329 Gene3D G3DSA:3.40.50.2300 62 166 5.3E-6 T 29-03-2018 MC49_RS18180 c231ac3b4a5ed0072034613d10ddd38c 329 Gene3D G3DSA:1.10.260.40 2 61 3.6E-18 T 29-03-2018 MC49_RS18180 c231ac3b4a5ed0072034613d10ddd38c 329 Gene3D G3DSA:3.40.50.2300 167 329 2.2E-37 T 29-03-2018 MC49_RS18180 c231ac3b4a5ed0072034613d10ddd38c 329 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 5.0E-7 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MC49_RS18180 c231ac3b4a5ed0072034613d10ddd38c 329 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 5.0E-7 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MC49_RS18180 c231ac3b4a5ed0072034613d10ddd38c 329 Pfam PF13377 Periplasmic binding protein-like domain 169 328 6.1E-34 T 29-03-2018 MC49_RS18180 c231ac3b4a5ed0072034613d10ddd38c 329 SUPERFAMILY SSF47413 1 54 5.63E-13 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS18180 c231ac3b4a5ed0072034613d10ddd38c 329 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 29-03-2018 MC49_RS18180 c231ac3b4a5ed0072034613d10ddd38c 329 SUPERFAMILY SSF53822 78 312 3.64E-42 T 29-03-2018 IPR028082 Periplasmic binding protein-like I MC49_RS02190 c6ed93186f576780bccfd1a07939cdca 88 Pfam PF05488 PAAR motif 10 79 1.6E-23 T 29-03-2018 IPR008727 PAAR motif MC49_RS12430 bde7c069636252a7803a7111e632644f 333 SUPERFAMILY SSF103088 154 265 1.2E-20 T 29-03-2018 IPR006665 OmpA-like domain MC49_RS12430 bde7c069636252a7803a7111e632644f 333 Gene3D G3DSA:3.30.1330.60 109 292 1.9E-35 T 29-03-2018 IPR006665 OmpA-like domain MC49_RS12430 bde7c069636252a7803a7111e632644f 333 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 12 66 1.3E-20 T 29-03-2018 IPR025713 Motility protein B, N-terminal domain MC49_RS12430 bde7c069636252a7803a7111e632644f 333 Pfam PF00691 OmpA family 162 252 1.5E-12 T 29-03-2018 IPR006665 OmpA-like domain MC49_RS18625 1a1a954acca111d06365dc43a31c490c 385 SMART SM00865 206 324 4.3E-56 T 29-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 MC49_RS18625 1a1a954acca111d06365dc43a31c490c 385 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 13 172 2.0E-42 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MC49_RS18625 1a1a954acca111d06365dc43a31c490c 385 SUPERFAMILY SSF55307 203 319 8.7E-43 T 29-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 MC49_RS18625 1a1a954acca111d06365dc43a31c490c 385 Gene3D G3DSA:3.40.50.1440 8 213 6.7E-43 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MC49_RS18625 1a1a954acca111d06365dc43a31c490c 385 PRINTS PR00423 Cell division protein FtsZ signature 97 117 4.6E-52 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MC49_RS18625 1a1a954acca111d06365dc43a31c490c 385 PRINTS PR00423 Cell division protein FtsZ signature 125 146 4.6E-52 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MC49_RS18625 1a1a954acca111d06365dc43a31c490c 385 PRINTS PR00423 Cell division protein FtsZ signature 188 210 4.6E-52 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MC49_RS18625 1a1a954acca111d06365dc43a31c490c 385 PRINTS PR00423 Cell division protein FtsZ signature 211 232 4.6E-52 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MC49_RS18625 1a1a954acca111d06365dc43a31c490c 385 ProSitePatterns PS01134 FtsZ protein signature 1. 43 77 - T 29-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 MC49_RS18625 1a1a954acca111d06365dc43a31c490c 385 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 8 354 38.379 T 29-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 MC49_RS18625 1a1a954acca111d06365dc43a31c490c 385 SMART SM00864 12 204 1.0E-112 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MC49_RS18625 1a1a954acca111d06365dc43a31c490c 385 ProSitePatterns PS01135 FtsZ protein signature 2. 96 117 - T 29-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 MC49_RS18625 1a1a954acca111d06365dc43a31c490c 385 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 7 336 2.2E-142 T 29-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 MC49_RS18625 1a1a954acca111d06365dc43a31c490c 385 Gene3D G3DSA:3.30.1330.20 214 324 1.9E-44 T 29-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 MC49_RS18625 1a1a954acca111d06365dc43a31c490c 385 Pfam PF12327 FtsZ family, C-terminal domain 221 315 1.7E-37 T 29-03-2018 IPR024757 Cell division protein FtsZ, C-terminal MC49_RS18625 1a1a954acca111d06365dc43a31c490c 385 SUPERFAMILY SSF52490 12 207 2.88E-70 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MC49_RS05005 adc3de19ffb9fd0b2cdfc03e50f59466 402 SUPERFAMILY SSF53098 1 376 1.82E-70 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MC49_RS05005 adc3de19ffb9fd0b2cdfc03e50f59466 402 Gene3D G3DSA:3.90.350.10 50 313 4.7E-21 T 29-03-2018 IPR014736 Transposase, Tn5-like, core MC49_RS05005 adc3de19ffb9fd0b2cdfc03e50f59466 402 Pfam PF01609 Transposase DDE domain 91 327 7.5E-27 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MC49_RS02355 adc3de19ffb9fd0b2cdfc03e50f59466 402 SUPERFAMILY SSF53098 1 376 1.82E-70 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MC49_RS02355 adc3de19ffb9fd0b2cdfc03e50f59466 402 Gene3D G3DSA:3.90.350.10 50 313 4.7E-21 T 29-03-2018 IPR014736 Transposase, Tn5-like, core MC49_RS02355 adc3de19ffb9fd0b2cdfc03e50f59466 402 Pfam PF01609 Transposase DDE domain 91 327 7.5E-27 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MC49_RS05285 adc3de19ffb9fd0b2cdfc03e50f59466 402 SUPERFAMILY SSF53098 1 376 1.82E-70 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MC49_RS05285 adc3de19ffb9fd0b2cdfc03e50f59466 402 Gene3D G3DSA:3.90.350.10 50 313 4.7E-21 T 29-03-2018 IPR014736 Transposase, Tn5-like, core MC49_RS05285 adc3de19ffb9fd0b2cdfc03e50f59466 402 Pfam PF01609 Transposase DDE domain 91 327 7.5E-27 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MC49_RS18560 adc3de19ffb9fd0b2cdfc03e50f59466 402 SUPERFAMILY SSF53098 1 376 1.82E-70 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MC49_RS18560 adc3de19ffb9fd0b2cdfc03e50f59466 402 Gene3D G3DSA:3.90.350.10 50 313 4.7E-21 T 29-03-2018 IPR014736 Transposase, Tn5-like, core MC49_RS18560 adc3de19ffb9fd0b2cdfc03e50f59466 402 Pfam PF01609 Transposase DDE domain 91 327 7.5E-27 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MC49_RS19060 adc3de19ffb9fd0b2cdfc03e50f59466 402 SUPERFAMILY SSF53098 1 376 1.82E-70 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MC49_RS19060 adc3de19ffb9fd0b2cdfc03e50f59466 402 Gene3D G3DSA:3.90.350.10 50 313 4.7E-21 T 29-03-2018 IPR014736 Transposase, Tn5-like, core MC49_RS19060 adc3de19ffb9fd0b2cdfc03e50f59466 402 Pfam PF01609 Transposase DDE domain 91 327 7.5E-27 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MC49_RS13320 adc3de19ffb9fd0b2cdfc03e50f59466 402 SUPERFAMILY SSF53098 1 376 1.82E-70 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MC49_RS13320 adc3de19ffb9fd0b2cdfc03e50f59466 402 Gene3D G3DSA:3.90.350.10 50 313 4.7E-21 T 29-03-2018 IPR014736 Transposase, Tn5-like, core MC49_RS13320 adc3de19ffb9fd0b2cdfc03e50f59466 402 Pfam PF01609 Transposase DDE domain 91 327 7.5E-27 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MC49_RS00905 d84c8774ba8e8f003b7e372154bf72aa 200 PIRSF PIRSF000239 1 199 3.2E-58 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MC49_RS00905 d84c8774ba8e8f003b7e372154bf72aa 200 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 160 195 2.0E-10 T 29-03-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MC49_RS00905 d84c8774ba8e8f003b7e372154bf72aa 200 Gene3D G3DSA:3.40.30.10 3 161 6.7E-40 T 29-03-2018 MC49_RS00905 d84c8774ba8e8f003b7e372154bf72aa 200 SUPERFAMILY SSF52833 1 196 1.04E-66 T 29-03-2018 IPR012336 Thioredoxin-like fold MC49_RS00905 d84c8774ba8e8f003b7e372154bf72aa 200 Gene3D G3DSA:3.30.1020.10 162 199 1.9E-14 T 29-03-2018 MC49_RS00905 d84c8774ba8e8f003b7e372154bf72aa 200 Pfam PF00578 AhpC/TSA family 5 139 3.3E-35 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MC49_RS09030 eb3e0d7c9ba7a97774500bbf208d47fc 518 Pfam PF01743 Poly A polymerase head domain 109 243 2.5E-38 T 29-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 MC49_RS09030 eb3e0d7c9ba7a97774500bbf208d47fc 518 Gene3D G3DSA:3.30.460.10 75 240 1.5E-50 T 29-03-2018 MC49_RS09030 eb3e0d7c9ba7a97774500bbf208d47fc 518 TIGRFAM TIGR01942 pcnB: poly(A) polymerase 78 511 1.6E-163 T 29-03-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 MC49_RS09030 eb3e0d7c9ba7a97774500bbf208d47fc 518 SUPERFAMILY SSF81301 81 240 2.83E-39 T 29-03-2018 MC49_RS09030 eb3e0d7c9ba7a97774500bbf208d47fc 518 SUPERFAMILY SSF81891 241 479 3.92E-50 T 29-03-2018 MC49_RS09030 eb3e0d7c9ba7a97774500bbf208d47fc 518 Pfam PF12626 Polymerase A arginine-rich C-terminus 388 505 2.5E-40 T 29-03-2018 IPR025866 Polymerase A arginine-rich C-terminal domain MC49_RS09030 eb3e0d7c9ba7a97774500bbf208d47fc 518 Hamap MF_00957 Poly(A) polymerase I [pcnB]. 46 508 38.954 T 29-03-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 MC49_RS09030 eb3e0d7c9ba7a97774500bbf208d47fc 518 Gene3D G3DSA:1.10.3090.10 241 487 1.9E-45 T 29-03-2018 MC49_RS09030 eb3e0d7c9ba7a97774500bbf208d47fc 518 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 270 329 6.4E-21 T 29-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 MC49_RS08035 3023602bf494a66304ca14e2b9c378e9 283 Gene3D G3DSA:1.10.8.10 1 56 9.0E-25 T 29-03-2018 MC49_RS08035 3023602bf494a66304ca14e2b9c378e9 283 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 29-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MC49_RS08035 3023602bf494a66304ca14e2b9c378e9 283 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 283 3.5E-112 T 29-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MC49_RS08035 3023602bf494a66304ca14e2b9c378e9 283 SUPERFAMILY SSF54713 144 281 1.05E-51 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MC49_RS08035 3023602bf494a66304ca14e2b9c378e9 283 SUPERFAMILY SSF54713 56 141 5.01E-19 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MC49_RS08035 3023602bf494a66304ca14e2b9c378e9 283 Gene3D G3DSA:3.30.479.20 57 144 1.2E-13 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MC49_RS08035 3023602bf494a66304ca14e2b9c378e9 283 Gene3D G3DSA:3.30.479.20 145 281 1.3E-47 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MC49_RS08035 3023602bf494a66304ca14e2b9c378e9 283 Hamap MF_00050 Elongation factor Ts [tsf]. 1 282 78.169 T 29-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MC49_RS08035 3023602bf494a66304ca14e2b9c378e9 283 Pfam PF00889 Elongation factor TS 73 265 7.5E-65 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MC49_RS08035 3023602bf494a66304ca14e2b9c378e9 283 SUPERFAMILY SSF46934 4 55 7.99E-19 T 29-03-2018 IPR009060 UBA-like GO:0005515 MC49_RS08035 3023602bf494a66304ca14e2b9c378e9 283 ProSitePatterns PS01127 Elongation factor Ts signature 2. 77 87 - T 29-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MC49_RS02640 de9d2fbc6a2d6a02d8040180e33c1293 281 PIRSF PIRSF006250 1 280 1.2E-69 T 29-03-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 MC49_RS02640 de9d2fbc6a2d6a02d8040180e33c1293 281 Gene3D G3DSA:3.20.20.70 129 267 3.0E-24 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS02640 de9d2fbc6a2d6a02d8040180e33c1293 281 SUPERFAMILY SSF51690 109 277 2.59E-36 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 MC49_RS02640 de9d2fbc6a2d6a02d8040180e33c1293 281 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 18 104 9.8E-20 T 29-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 MC49_RS02640 de9d2fbc6a2d6a02d8040180e33c1293 281 Gene3D G3DSA:3.90.1170.20 4 128 5.4E-19 T 29-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 MC49_RS02640 de9d2fbc6a2d6a02d8040180e33c1293 281 TIGRFAM TIGR01334 modD: modD protein 2 278 3.2E-112 T 29-03-2018 IPR006242 Putative pyrophosphorylase ModD GO:0016763 MC49_RS02640 de9d2fbc6a2d6a02d8040180e33c1293 281 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 106 276 4.3E-31 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 MC49_RS02640 de9d2fbc6a2d6a02d8040180e33c1293 281 SUPERFAMILY SSF54675 3 105 1.41E-20 T 29-03-2018 MC49_RS16395 e5a75cbf53241ad0112692580c83d963 203 Gene3D G3DSA:1.20.1050.10 86 203 9.7E-22 T 29-03-2018 MC49_RS16395 e5a75cbf53241ad0112692580c83d963 203 Pfam PF02798 Glutathione S-transferase, N-terminal domain 3 68 4.1E-10 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MC49_RS16395 e5a75cbf53241ad0112692580c83d963 203 Pfam PF00043 Glutathione S-transferase, C-terminal domain 128 190 3.5E-8 T 29-03-2018 IPR004046 Glutathione S-transferase, C-terminal MC49_RS16395 e5a75cbf53241ad0112692580c83d963 203 SUPERFAMILY SSF52833 1 78 2.61E-16 T 29-03-2018 IPR012336 Thioredoxin-like fold MC49_RS16395 e5a75cbf53241ad0112692580c83d963 203 Gene3D G3DSA:3.40.30.10 1 85 1.0E-22 T 29-03-2018 MC49_RS16395 e5a75cbf53241ad0112692580c83d963 203 SUPERFAMILY SSF47616 73 193 1.53E-24 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like MC49_RS03495 0c32d41aa0f6f777e49bfd9d21de1388 120 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 3 109 1.3E-22 T 29-03-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like MC49_RS03495 0c32d41aa0f6f777e49bfd9d21de1388 120 SUPERFAMILY SSF110857 1 116 1.31E-31 T 29-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like MC49_RS03495 0c32d41aa0f6f777e49bfd9d21de1388 120 Gene3D G3DSA:3.10.490.10 1 120 2.9E-26 T 29-03-2018 MC49_RS12040 f1dba7bfeeba6dd982a77730ea4210c3 932 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 71 94 - T 29-03-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 MC49_RS12040 f1dba7bfeeba6dd982a77730ea4210c3 932 Pfam PF05193 Peptidase M16 inactive domain 688 856 3.1E-11 T 29-03-2018 IPR007863 Peptidase M16, C-terminal MC49_RS12040 f1dba7bfeeba6dd982a77730ea4210c3 932 Pfam PF05193 Peptidase M16 inactive domain 210 390 6.8E-18 T 29-03-2018 IPR007863 Peptidase M16, C-terminal MC49_RS12040 f1dba7bfeeba6dd982a77730ea4210c3 932 Gene3D G3DSA:3.30.830.10 272 484 7.3E-20 T 29-03-2018 MC49_RS12040 f1dba7bfeeba6dd982a77730ea4210c3 932 Gene3D G3DSA:3.30.830.10 749 932 3.6E-9 T 29-03-2018 MC49_RS12040 f1dba7bfeeba6dd982a77730ea4210c3 932 SUPERFAMILY SSF63411 779 919 8.98E-8 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MC49_RS12040 f1dba7bfeeba6dd982a77730ea4210c3 932 Gene3D G3DSA:3.30.830.10 15 266 2.5E-51 T 29-03-2018 MC49_RS12040 f1dba7bfeeba6dd982a77730ea4210c3 932 Gene3D G3DSA:3.30.830.10 518 740 4.7E-18 T 29-03-2018 MC49_RS12040 f1dba7bfeeba6dd982a77730ea4210c3 932 SUPERFAMILY SSF63411 268 464 6.67E-5 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MC49_RS12040 f1dba7bfeeba6dd982a77730ea4210c3 932 SUPERFAMILY SSF63411 37 260 1.73E-45 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MC49_RS12040 f1dba7bfeeba6dd982a77730ea4210c3 932 SUPERFAMILY SSF63411 512 733 3.33E-22 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MC49_RS12040 f1dba7bfeeba6dd982a77730ea4210c3 932 Pfam PF00675 Insulinase (Peptidase family M16) 51 173 1.5E-31 T 29-03-2018 IPR011765 Peptidase M16, N-terminal MC49_RS12025 6c5f58aedf107abe3f3cc9b368ec164b 1295 SUPERFAMILY SSF55326 220 427 1.12E-66 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MC49_RS12025 6c5f58aedf107abe3f3cc9b368ec164b 1295 Gene3D G3DSA:3.30.1330.10 217 424 2.6E-51 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MC49_RS12025 6c5f58aedf107abe3f3cc9b368ec164b 1295 Gene3D G3DSA:3.30.1330.10 612 812 4.0E-19 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MC49_RS12025 6c5f58aedf107abe3f3cc9b368ec164b 1295 Gene3D G3DSA:3.30.1330.10 182 216 0.0042 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MC49_RS12025 6c5f58aedf107abe3f3cc9b368ec164b 1295 SUPERFAMILY SSF82697 1 150 1.57E-51 T 29-03-2018 MC49_RS12025 6c5f58aedf107abe3f3cc9b368ec164b 1295 TIGRFAM TIGR01735 FGAM_synt: phosphoribosylformylglycinamidine synthase 3 1293 0.0 T 29-03-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MC49_RS12025 6c5f58aedf107abe3f3cc9b368ec164b 1295 SMART SM01211 1039 1294 1.4E-158 T 29-03-2018 MC49_RS12025 6c5f58aedf107abe3f3cc9b368ec164b 1295 Gene3D G3DSA:3.90.650.10 824 994 5.7E-24 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MC49_RS12025 6c5f58aedf107abe3f3cc9b368ec164b 1295 Gene3D G3DSA:3.90.650.10 425 607 7.8E-31 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MC49_RS12025 6c5f58aedf107abe3f3cc9b368ec164b 1295 Pfam PF02769 AIR synthase related protein, C-terminal domain 833 966 6.4E-13 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MC49_RS12025 6c5f58aedf107abe3f3cc9b368ec164b 1295 Pfam PF02769 AIR synthase related protein, C-terminal domain 431 586 7.2E-28 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MC49_RS12025 6c5f58aedf107abe3f3cc9b368ec164b 1295 SUPERFAMILY SSF109736 154 219 3.14E-21 T 29-03-2018 MC49_RS12025 6c5f58aedf107abe3f3cc9b368ec164b 1295 Hamap MF_00419 Phosphoribosylformylglycinamidine synthase [purL]. 1 1295 21.418 T 29-03-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MC49_RS12025 6c5f58aedf107abe3f3cc9b368ec164b 1295 SUPERFAMILY SSF52317 1035 1293 1.24E-98 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MC49_RS12025 6c5f58aedf107abe3f3cc9b368ec164b 1295 SUPERFAMILY SSF56042 823 1033 4.49E-50 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MC49_RS12025 6c5f58aedf107abe3f3cc9b368ec164b 1295 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 1039 1292 2.7E-106 T 29-03-2018 MC49_RS12025 6c5f58aedf107abe3f3cc9b368ec164b 1295 SUPERFAMILY SSF56042 430 614 2.84E-53 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MC49_RS12025 6c5f58aedf107abe3f3cc9b368ec164b 1295 SUPERFAMILY SSF55326 617 815 2.41E-67 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MC49_RS12025 6c5f58aedf107abe3f3cc9b368ec164b 1295 Gene3D G3DSA:3.40.50.880 1038 1294 6.9E-32 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MC49_RS09575 84b34d530e32868ce6897eb0e8d563fe 239 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 49 238 4.1E-72 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 MC49_RS09575 84b34d530e32868ce6897eb0e8d563fe 239 SUPERFAMILY SSF53335 18 237 1.71E-38 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS09575 84b34d530e32868ce6897eb0e8d563fe 239 Gene3D G3DSA:3.40.50.150 30 239 3.2E-29 T 29-03-2018 MC49_RS09575 84b34d530e32868ce6897eb0e8d563fe 239 Pfam PF02390 Putative methyltransferase 64 233 5.9E-61 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 MC49_RS09575 84b34d530e32868ce6897eb0e8d563fe 239 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 24 238 30.205 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 MC49_RS18530 384c9e2079c2fe3f5e9fda160567da74 475 Gene3D G3DSA:3.30.390.30 337 462 5.2E-37 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 MC49_RS18530 384c9e2079c2fe3f5e9fda160567da74 475 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 328 5.9E-64 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS18530 384c9e2079c2fe3f5e9fda160567da74 475 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 347 455 9.6E-35 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MC49_RS18530 384c9e2079c2fe3f5e9fda160567da74 475 Gene3D G3DSA:3.50.50.60 1 167 3.3E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS18530 384c9e2079c2fe3f5e9fda160567da74 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 408 423 1.0E-68 T 29-03-2018 MC49_RS18530 384c9e2079c2fe3f5e9fda160567da74 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 141 150 1.0E-68 T 29-03-2018 MC49_RS18530 384c9e2079c2fe3f5e9fda160567da74 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 265 279 1.0E-68 T 29-03-2018 MC49_RS18530 384c9e2079c2fe3f5e9fda160567da74 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 430 450 1.0E-68 T 29-03-2018 MC49_RS18530 384c9e2079c2fe3f5e9fda160567da74 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 308 315 1.0E-68 T 29-03-2018 MC49_RS18530 384c9e2079c2fe3f5e9fda160567da74 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 1.0E-68 T 29-03-2018 MC49_RS18530 384c9e2079c2fe3f5e9fda160567da74 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 177 202 1.0E-68 T 29-03-2018 MC49_RS18530 384c9e2079c2fe3f5e9fda160567da74 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 343 364 1.0E-68 T 29-03-2018 MC49_RS18530 384c9e2079c2fe3f5e9fda160567da74 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 41 56 1.0E-68 T 29-03-2018 MC49_RS18530 384c9e2079c2fe3f5e9fda160567da74 475 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 8 459 1.9E-148 T 29-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 MC49_RS18530 384c9e2079c2fe3f5e9fda160567da74 475 SUPERFAMILY SSF51905 2 337 1.48E-58 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS18530 384c9e2079c2fe3f5e9fda160567da74 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 3.3E-41 T 29-03-2018 MC49_RS18530 384c9e2079c2fe3f5e9fda160567da74 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 177 195 3.3E-41 T 29-03-2018 MC49_RS18530 384c9e2079c2fe3f5e9fda160567da74 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 280 3.3E-41 T 29-03-2018 MC49_RS18530 384c9e2079c2fe3f5e9fda160567da74 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 138 156 3.3E-41 T 29-03-2018 MC49_RS18530 384c9e2079c2fe3f5e9fda160567da74 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 293 315 3.3E-41 T 29-03-2018 MC49_RS18530 384c9e2079c2fe3f5e9fda160567da74 475 Gene3D G3DSA:3.40.50.720 168 336 2.7E-29 T 29-03-2018 MC49_RS18530 384c9e2079c2fe3f5e9fda160567da74 475 SUPERFAMILY SSF55424 343 466 4.98E-39 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 MC49_RS18530 384c9e2079c2fe3f5e9fda160567da74 475 PIRSF PIRSF000350 1 468 2.8E-86 T 29-03-2018 MC49_RS18530 384c9e2079c2fe3f5e9fda160567da74 475 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 42 52 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 MC49_RS10435 886c67e42782d5e784a299726a64decf 130 PIRSF PIRSF003230 1 130 3.3E-48 T 29-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 MC49_RS10435 886c67e42782d5e784a299726a64decf 130 SUPERFAMILY SSF54637 1 129 3.46E-41 T 29-03-2018 IPR029069 HotDog domain MC49_RS10435 886c67e42782d5e784a299726a64decf 130 Pfam PF03061 Thioesterase superfamily 16 101 4.0E-21 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MC49_RS10435 886c67e42782d5e784a299726a64decf 130 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 5 121 5.4E-42 T 29-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 MC49_RS10435 886c67e42782d5e784a299726a64decf 130 ProSitePatterns PS01328 4-hydroxybenzoyl-CoA thioesterase family active site. 7 24 - T 29-03-2018 IPR008272 4-hydroxybenzoyl-CoA thioesterase, active site GO:0016787 MC49_RS10435 886c67e42782d5e784a299726a64decf 130 TIGRFAM TIGR02799 thio_ybgC: tol-pal system-associated acyl-CoA thioesterase 2 126 2.5E-51 T 29-03-2018 IPR014166 Tol-Pal system-associated acyl-CoA thioesterase GO:0016790 MC49_RS10435 886c67e42782d5e784a299726a64decf 130 Gene3D G3DSA:3.10.129.10 1 130 5.7E-38 T 29-03-2018 MC49_RS05325 3685778b6b4104f2eec89c02e459dd8c 360 ProSitePatterns PS00618 RecF protein signature 2. 300 318 - T 29-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 MC49_RS05325 3685778b6b4104f2eec89c02e459dd8c 360 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 356 2.4E-40 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal MC49_RS05325 3685778b6b4104f2eec89c02e459dd8c 360 SUPERFAMILY SSF52540 1 358 3.14E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS05325 3685778b6b4104f2eec89c02e459dd8c 360 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 360 96.844 T 29-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 MC49_RS05325 3685778b6b4104f2eec89c02e459dd8c 360 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 357 1.6E-134 T 29-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 MC49_RS05325 3685778b6b4104f2eec89c02e459dd8c 360 ProSitePatterns PS00617 RecF protein signature 1. 119 139 - T 29-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 MC49_RS05325 3685778b6b4104f2eec89c02e459dd8c 360 Gene3D G3DSA:3.40.50.300 1 360 1.5E-32 T 29-03-2018 MC49_RS13470 aebd2f42c5f6391d861cdba64698a922 374 Gene3D G3DSA:3.40.50.2000 188 367 2.9E-30 T 29-03-2018 MC49_RS13470 aebd2f42c5f6391d861cdba64698a922 374 Gene3D G3DSA:3.40.50.2000 31 187 1.3E-21 T 29-03-2018 MC49_RS13470 aebd2f42c5f6391d861cdba64698a922 374 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 205 324 7.8E-24 T 29-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 MC49_RS13470 aebd2f42c5f6391d861cdba64698a922 374 SUPERFAMILY SSF53756 39 363 1.15E-55 T 29-03-2018 MC49_RS13345 c3105da86ca9af4babf9ccfd265fba64 358 SUPERFAMILY SSF53756 6 329 3.93E-44 T 29-03-2018 MC49_RS13345 c3105da86ca9af4babf9ccfd265fba64 358 Pfam PF13439 Glycosyltransferase Family 4 17 171 3.4E-9 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 MC49_RS13345 c3105da86ca9af4babf9ccfd265fba64 358 Gene3D G3DSA:3.40.50.2000 164 344 5.0E-23 T 29-03-2018 MC49_RS13345 c3105da86ca9af4babf9ccfd265fba64 358 Pfam PF00534 Glycosyl transferases group 1 183 339 9.6E-23 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 MC49_RS13345 c3105da86ca9af4babf9ccfd265fba64 358 Gene3D G3DSA:3.40.50.2000 15 163 1.5E-5 T 29-03-2018 MC49_RS08625 9aa4d498fd042027e3b23b2ca6dfecdf 450 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 263 274 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MC49_RS08625 9aa4d498fd042027e3b23b2ca6dfecdf 450 Pfam PF13375 RnfC Barrel sandwich hybrid domain 381 447 1.7E-17 T 29-03-2018 IPR026902 RnfC Barrel sandwich hybrid domain MC49_RS08625 9aa4d498fd042027e3b23b2ca6dfecdf 450 Gene3D G3DSA:3.10.560.10 160 249 3.6E-4 T 29-03-2018 MC49_RS08625 9aa4d498fd042027e3b23b2ca6dfecdf 450 Gene3D G3DSA:3.30.70.20 250 270 0.011 T 29-03-2018 MC49_RS08625 9aa4d498fd042027e3b23b2ca6dfecdf 450 PIRSF PIRSF036408 12 450 2.4E-180 T 29-03-2018 IPR017054 Propanediol utilization protein, PduS, predicted MC49_RS08625 9aa4d498fd042027e3b23b2ca6dfecdf 450 SUPERFAMILY SSF142984 171 240 3.4E-13 T 29-03-2018 MC49_RS08625 9aa4d498fd042027e3b23b2ca6dfecdf 450 SUPERFAMILY SSF142019 8 177 2.09E-45 T 29-03-2018 MC49_RS08625 9aa4d498fd042027e3b23b2ca6dfecdf 450 Gene3D G3DSA:3.30.70.20 271 342 4.2E-5 T 29-03-2018 MC49_RS08625 9aa4d498fd042027e3b23b2ca6dfecdf 450 Pfam PF10531 SLBB domain 172 218 3.3E-10 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS08625 9aa4d498fd042027e3b23b2ca6dfecdf 450 SUPERFAMILY SSF46548 212 342 8.02E-12 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MC49_RS08625 9aa4d498fd042027e3b23b2ca6dfecdf 450 Pfam PF13534 4Fe-4S dicluster domain 263 323 2.5E-7 T 29-03-2018 MC49_RS08625 9aa4d498fd042027e3b23b2ca6dfecdf 450 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 20 159 5.8E-39 T 29-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS15410 12ef26957bb58fac214b46afe45bb9b0 620 Gene3D G3DSA:3.90.226.10 56 318 2.2E-22 T 29-03-2018 MC49_RS15410 12ef26957bb58fac214b46afe45bb9b0 620 Gene3D G3DSA:3.90.226.10 324 614 2.6E-48 T 29-03-2018 MC49_RS15410 12ef26957bb58fac214b46afe45bb9b0 620 TIGRFAM TIGR00705 SppA_67K: signal peptide peptidase SppA, 67K type 16 611 6.2E-205 T 29-03-2018 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 MC49_RS15410 12ef26957bb58fac214b46afe45bb9b0 620 PIRSF PIRSF001217 8 620 3.8E-210 T 29-03-2018 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 MC49_RS15410 12ef26957bb58fac214b46afe45bb9b0 620 SUPERFAMILY SSF52096 326 445 5.68E-42 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MC49_RS15410 12ef26957bb58fac214b46afe45bb9b0 620 SUPERFAMILY SSF52096 473 535 5.68E-42 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MC49_RS15410 12ef26957bb58fac214b46afe45bb9b0 620 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 332 545 5.5E-53 T 29-03-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 MC49_RS15410 12ef26957bb58fac214b46afe45bb9b0 620 SUPERFAMILY SSF52096 212 287 1.24E-26 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MC49_RS15410 12ef26957bb58fac214b46afe45bb9b0 620 SUPERFAMILY SSF52096 51 181 1.24E-26 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MC49_RS15410 12ef26957bb58fac214b46afe45bb9b0 620 Pfam PF01343 Peptidase family S49 397 547 9.6E-48 T 29-03-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 MC49_RS15410 12ef26957bb58fac214b46afe45bb9b0 620 Pfam PF01343 Peptidase family S49 141 286 2.8E-33 T 29-03-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 MC49_RS18780 391aa85d2ac67e0f63dc50c51c17f154 399 Pfam PF07055 Enoyl reductase FAD binding domain 324 386 1.5E-29 T 29-03-2018 IPR024906 Enoyl reductase FAD binding domain KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MC49_RS18780 391aa85d2ac67e0f63dc50c51c17f154 399 Pfam PF12242 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2 80 4.6E-38 T 29-03-2018 IPR010758 Trans-2-enoyl-CoA reductase GO:0016491|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MC49_RS18780 391aa85d2ac67e0f63dc50c51c17f154 399 Hamap MF_01838 Trans-2-enoyl-CoA reductase [NADH] [fabV]. 1 393 56.317 T 29-03-2018 IPR010758 Trans-2-enoyl-CoA reductase GO:0016491|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MC49_RS18780 391aa85d2ac67e0f63dc50c51c17f154 399 Pfam PF12241 Trans-2-enoyl-CoA reductase catalytic region 82 317 1.4E-115 T 29-03-2018 IPR024910 Trans-2-enoyl-CoA reductase catalytic domain, putative KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MC49_RS09685 9216cbc0d71afc34fce8df61a5f38de2 816 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 360 507 2.3E-10 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MC49_RS09685 9216cbc0d71afc34fce8df61a5f38de2 816 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 146 233 6.7E-18 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MC49_RS09685 9216cbc0d71afc34fce8df61a5f38de2 816 Gene3D G3DSA:2.40.110.10 236 349 1.6E-17 T 29-03-2018 MC49_RS09685 9216cbc0d71afc34fce8df61a5f38de2 816 Gene3D G3DSA:1.10.540.10 76 235 1.1E-31 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MC49_RS09685 9216cbc0d71afc34fce8df61a5f38de2 816 Pfam PF09317 Domain of unknown function (DUF1974) 514 792 4.2E-110 T 29-03-2018 IPR015396 Acyl-CoA dehydrogenase, C-termina, bacterial type GO:0003995|GO:0033539|GO:0055114 MC49_RS09685 9216cbc0d71afc34fce8df61a5f38de2 816 Gene3D G3DSA:1.20.140.10 350 510 5.0E-19 T 29-03-2018 MC49_RS09685 9216cbc0d71afc34fce8df61a5f38de2 816 SUPERFAMILY SSF56645 119 355 4.19E-48 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 MC49_RS09685 9216cbc0d71afc34fce8df61a5f38de2 816 SUPERFAMILY SSF47203 360 507 2.26E-21 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MC49_RS07215 328f486bc143a43f67d6dd5344b9b9b7 625 Gene3D G3DSA:3.20.20.300 27 418 7.7E-91 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MC49_RS07215 328f486bc143a43f67d6dd5344b9b9b7 625 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 304 321 - T 29-03-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 MC49_RS07215 328f486bc143a43f67d6dd5344b9b9b7 625 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 47 390 1.1E-87 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MC49_RS07215 328f486bc143a43f67d6dd5344b9b9b7 625 SUPERFAMILY SSF51445 29 424 1.0E-87 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily MC49_RS02855 8a870d33c36afaa7b578fbb96989c755 112 SUPERFAMILY SSF81901 32 100 6.8E-11 T 29-03-2018 MC49_RS02855 8a870d33c36afaa7b578fbb96989c755 112 Gene3D G3DSA:2.60.40.1180 23 109 3.4E-11 T 29-03-2018 MC49_RS02855 8a870d33c36afaa7b578fbb96989c755 112 SMART SM00671 39 75 6.2E-7 T 29-03-2018 IPR006597 Sel1-like repeat MC49_RS08260 d199165b63aa28b4d1999c0311dd1c5d 330 Gene3D G3DSA:1.10.10.10 257 326 5.6E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS08260 d199165b63aa28b4d1999c0311dd1c5d 330 Pfam PF04542 Sigma-70 region 2 95 164 8.1E-20 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS08260 d199165b63aa28b4d1999c0311dd1c5d 330 SUPERFAMILY SSF88659 168 242 1.31E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS08260 d199165b63aa28b4d1999c0311dd1c5d 330 Gene3D G3DSA:1.10.10.10 165 215 1.6E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS08260 d199165b63aa28b4d1999c0311dd1c5d 330 SUPERFAMILY SSF88659 226 322 7.48E-24 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS08260 d199165b63aa28b4d1999c0311dd1c5d 330 Pfam PF04539 Sigma-70 region 3 175 249 3.4E-22 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS08260 d199165b63aa28b4d1999c0311dd1c5d 330 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 91 317 1.1E-35 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS08260 d199165b63aa28b4d1999c0311dd1c5d 330 Pfam PF00140 Sigma-70 factor, region 1.2 57 89 4.3E-11 T 29-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS08260 d199165b63aa28b4d1999c0311dd1c5d 330 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 288 314 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS08260 d199165b63aa28b4d1999c0311dd1c5d 330 SUPERFAMILY SSF88946 57 165 3.79E-45 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS08260 d199165b63aa28b4d1999c0311dd1c5d 330 Pfam PF04545 Sigma-70, region 4 263 315 1.9E-15 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS08260 d199165b63aa28b4d1999c0311dd1c5d 330 TIGRFAM TIGR02394 rpoS_proteo: RNA polymerase sigma factor RpoS 51 329 3.3E-139 T 29-03-2018 IPR012761 RNA polymerase sigma factor RpoS GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS08260 d199165b63aa28b4d1999c0311dd1c5d 330 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 119 132 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS08260 d199165b63aa28b4d1999c0311dd1c5d 330 Gene3D G3DSA:1.10.601.10 5 164 1.6E-59 T 29-03-2018 MC49_RS08260 d199165b63aa28b4d1999c0311dd1c5d 330 Hamap MF_00959 RNA polymerase sigma factor RpoS [rpoS]. 1 329 39.575 T 29-03-2018 IPR012761 RNA polymerase sigma factor RpoS GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS08260 d199165b63aa28b4d1999c0311dd1c5d 330 PRINTS PR00046 Major sigma-70 factor signature 143 151 1.2E-27 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS08260 d199165b63aa28b4d1999c0311dd1c5d 330 PRINTS PR00046 Major sigma-70 factor signature 119 132 1.2E-27 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS08260 d199165b63aa28b4d1999c0311dd1c5d 330 PRINTS PR00046 Major sigma-70 factor signature 267 279 1.2E-27 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS08260 d199165b63aa28b4d1999c0311dd1c5d 330 PRINTS PR00046 Major sigma-70 factor signature 303 314 1.2E-27 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS08260 d199165b63aa28b4d1999c0311dd1c5d 330 PRINTS PR00046 Major sigma-70 factor signature 288 303 1.2E-27 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS04800 3b34c3d7d801738029ea9aca06d37f9d 682 SUPERFAMILY SSF55486 2 679 7.81E-210 T 29-03-2018 MC49_RS04800 3b34c3d7d801738029ea9aca06d37f9d 682 Gene3D G3DSA:1.10.1370.10 142 441 2.5E-57 T 29-03-2018 MC49_RS04800 3b34c3d7d801738029ea9aca06d37f9d 682 Gene3D G3DSA:1.10.1370.10 459 682 9.7E-66 T 29-03-2018 MC49_RS04800 3b34c3d7d801738029ea9aca06d37f9d 682 Pfam PF01432 Peptidase family M3 224 679 1.7E-164 T 29-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 MC49_RS04800 3b34c3d7d801738029ea9aca06d37f9d 682 Gene3D G3DSA:1.20.1050.40 6 140 1.7E-39 T 29-03-2018 IPR024080 Neurolysin/Thimet oligopeptidase, N-terminal MC49_RS00940 299ea4b5c9f55f66956d516f56236933 302 SUPERFAMILY SSF53067 2 299 8.07E-59 T 29-03-2018 MC49_RS00940 299ea4b5c9f55f66956d516f56236933 302 Pfam PF00480 ROK family 3 301 1.5E-84 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 MC49_RS00940 299ea4b5c9f55f66956d516f56236933 302 Gene3D G3DSA:3.30.420.40 1 115 9.5E-21 T 29-03-2018 MC49_RS00940 299ea4b5c9f55f66956d516f56236933 302 Gene3D G3DSA:3.30.420.40 116 302 4.8E-49 T 29-03-2018 MC49_RS00940 299ea4b5c9f55f66956d516f56236933 302 ProSitePatterns PS01125 ROK family signature. 130 157 - T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 MC49_RS00085 ff37e8318cd05d6ad909781933499437 111 SUPERFAMILY SSF46785 1 99 1.12E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS00085 ff37e8318cd05d6ad909781933499437 111 Gene3D G3DSA:1.10.10.10 2 86 1.6E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS00085 ff37e8318cd05d6ad909781933499437 111 Pfam PF01022 Bacterial regulatory protein, arsR family 12 57 9.0E-16 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MC49_RS00085 ff37e8318cd05d6ad909781933499437 111 SMART SM00418 5 83 2.4E-25 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MC49_RS00085 ff37e8318cd05d6ad909781933499437 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 7 22 1.4E-22 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MC49_RS00085 ff37e8318cd05d6ad909781933499437 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 40 55 1.4E-22 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MC49_RS00085 ff37e8318cd05d6ad909781933499437 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 27 38 1.4E-22 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MC49_RS00085 ff37e8318cd05d6ad909781933499437 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 1.4E-22 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MC49_RS00085 ff37e8318cd05d6ad909781933499437 111 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 29 47 - T 29-03-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 MC49_RS02440 aee869eab7e71225518a74dd10a744c6 252 Gene3D G3DSA:2.60.40.10 153 249 1.5E-21 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS02440 aee869eab7e71225518a74dd10a744c6 252 Gene3D G3DSA:2.60.40.10 27 146 2.6E-35 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS02440 aee869eab7e71225518a74dd10a744c6 252 PRINTS PR00969 Pili chaperone signature 166 181 6.2E-33 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS02440 aee869eab7e71225518a74dd10a744c6 252 PRINTS PR00969 Pili chaperone signature 127 142 6.2E-33 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS02440 aee869eab7e71225518a74dd10a744c6 252 PRINTS PR00969 Pili chaperone signature 74 95 6.2E-33 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS02440 aee869eab7e71225518a74dd10a744c6 252 PRINTS PR00969 Pili chaperone signature 28 37 6.2E-33 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS02440 aee869eab7e71225518a74dd10a744c6 252 PRINTS PR00969 Pili chaperone signature 104 121 6.2E-33 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS02440 aee869eab7e71225518a74dd10a744c6 252 ProSitePatterns PS00635 Gram-negative pili assembly chaperone signature. 103 120 - T 29-03-2018 IPR018046 Pili assembly chaperone, conserved site MC49_RS02440 aee869eab7e71225518a74dd10a744c6 252 SUPERFAMILY SSF49584 154 245 8.9E-23 T 29-03-2018 IPR016148 Pili assembly chaperone, C-terminal MC49_RS02440 aee869eab7e71225518a74dd10a744c6 252 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 171 232 1.9E-16 T 29-03-2018 IPR016148 Pili assembly chaperone, C-terminal MC49_RS02440 aee869eab7e71225518a74dd10a744c6 252 SUPERFAMILY SSF49354 28 145 1.47E-38 T 29-03-2018 IPR008962 PapD-like MC49_RS02440 aee869eab7e71225518a74dd10a744c6 252 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 28 145 1.2E-37 T 29-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 MC49_RS02615 159cd718f60ba822f2643f0bbecae9b7 331 SMART SM00354 5 75 1.4E-23 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MC49_RS02615 159cd718f60ba822f2643f0bbecae9b7 331 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 52 3.2E-15 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MC49_RS02615 159cd718f60ba822f2643f0bbecae9b7 331 Pfam PF13377 Periplasmic binding protein-like domain 173 330 2.1E-29 T 29-03-2018 MC49_RS02615 159cd718f60ba822f2643f0bbecae9b7 331 Gene3D G3DSA:3.40.50.2300 62 171 4.5E-26 T 29-03-2018 MC49_RS02615 159cd718f60ba822f2643f0bbecae9b7 331 SUPERFAMILY SSF53822 63 318 8.78E-62 T 29-03-2018 IPR028082 Periplasmic binding protein-like I MC49_RS02615 159cd718f60ba822f2643f0bbecae9b7 331 SUPERFAMILY SSF47413 4 62 1.13E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS02615 159cd718f60ba822f2643f0bbecae9b7 331 ProSitePatterns PS00356 LacI-type HTH domain signature. 8 26 - T 29-03-2018 MC49_RS02615 159cd718f60ba822f2643f0bbecae9b7 331 Gene3D G3DSA:1.10.260.40 7 61 7.3E-13 T 29-03-2018 MC49_RS02615 159cd718f60ba822f2643f0bbecae9b7 331 Gene3D G3DSA:3.40.50.2300 172 331 4.9E-40 T 29-03-2018 MC49_RS06320 8483902f041610e6c21fe14bb6c2a12e 642 Gene3D G3DSA:3.40.50.300 2 279 1.9E-53 T 29-03-2018 MC49_RS06320 8483902f041610e6c21fe14bb6c2a12e 642 Pfam PF00005 ABC transporter 328 459 8.6E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS06320 8483902f041610e6c21fe14bb6c2a12e 642 Pfam PF00005 ABC transporter 17 178 9.8E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS06320 8483902f041610e6c21fe14bb6c2a12e 642 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS06320 8483902f041610e6c21fe14bb6c2a12e 642 SUPERFAMILY SSF52540 119 251 3.64E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS06320 8483902f041610e6c21fe14bb6c2a12e 642 SUPERFAMILY SSF52540 2 92 3.64E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS06320 8483902f041610e6c21fe14bb6c2a12e 642 Gene3D G3DSA:3.40.50.300 309 629 9.6E-53 T 29-03-2018 MC49_RS06320 8483902f041610e6c21fe14bb6c2a12e 642 ProSitePatterns PS00211 ABC transporters family signature. 431 445 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS06320 8483902f041610e6c21fe14bb6c2a12e 642 SUPERFAMILY SSF52540 296 515 3.03E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS06320 8483902f041610e6c21fe14bb6c2a12e 642 Pfam PF12848 ABC transporter 217 296 3.7E-27 T 29-03-2018 IPR032781 ABC-transporter extension domain MC49_RS06320 8483902f041610e6c21fe14bb6c2a12e 642 SMART SM00382 26 223 2.0E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS06320 8483902f041610e6c21fe14bb6c2a12e 642 SMART SM00382 337 506 5.6E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS08215 07314008bdc0ebcf28383b87d0ee2b2f 592 Gene3D G3DSA:3.40.50.80 446 592 2.1E-35 T 29-03-2018 MC49_RS08215 07314008bdc0ebcf28383b87d0ee2b2f 592 Pfam PF00175 Oxidoreductase NAD-binding domain 450 555 1.9E-17 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MC49_RS08215 07314008bdc0ebcf28383b87d0ee2b2f 592 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 379 386 6.5E-25 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MC49_RS08215 07314008bdc0ebcf28383b87d0ee2b2f 592 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 518 534 6.5E-25 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MC49_RS08215 07314008bdc0ebcf28383b87d0ee2b2f 592 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 487 498 6.5E-25 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MC49_RS08215 07314008bdc0ebcf28383b87d0ee2b2f 592 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 263 273 6.5E-25 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MC49_RS08215 07314008bdc0ebcf28383b87d0ee2b2f 592 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 541 549 6.5E-25 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MC49_RS08215 07314008bdc0ebcf28383b87d0ee2b2f 592 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 449 468 6.5E-25 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MC49_RS08215 07314008bdc0ebcf28383b87d0ee2b2f 592 SUPERFAMILY SSF63380 222 439 8.51E-61 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MC49_RS08215 07314008bdc0ebcf28383b87d0ee2b2f 592 Pfam PF00258 Flavodoxin 60 182 1.6E-25 T 29-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 MC49_RS08215 07314008bdc0ebcf28383b87d0ee2b2f 592 Gene3D G3DSA:2.40.30.10 212 431 8.8E-43 T 29-03-2018 MC49_RS08215 07314008bdc0ebcf28383b87d0ee2b2f 592 Pfam PF00667 FAD binding domain 223 417 5.0E-29 T 29-03-2018 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 MC49_RS08215 07314008bdc0ebcf28383b87d0ee2b2f 592 PIRSF PIRSF000207 1 592 6.4E-203 T 29-03-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MC49_RS08215 07314008bdc0ebcf28383b87d0ee2b2f 592 SUPERFAMILY SSF52343 437 592 6.16E-49 T 29-03-2018 MC49_RS08215 07314008bdc0ebcf28383b87d0ee2b2f 592 PRINTS PR00369 Flavodoxin signature 136 146 1.1E-11 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MC49_RS08215 07314008bdc0ebcf28383b87d0ee2b2f 592 PRINTS PR00369 Flavodoxin signature 160 179 1.1E-11 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MC49_RS08215 07314008bdc0ebcf28383b87d0ee2b2f 592 PRINTS PR00369 Flavodoxin signature 104 115 1.1E-11 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MC49_RS08215 07314008bdc0ebcf28383b87d0ee2b2f 592 PRINTS PR00369 Flavodoxin signature 56 69 1.1E-11 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MC49_RS08215 07314008bdc0ebcf28383b87d0ee2b2f 592 SUPERFAMILY SSF52218 53 199 1.02E-40 T 29-03-2018 IPR029039 Flavoprotein-like domain MC49_RS08215 07314008bdc0ebcf28383b87d0ee2b2f 592 Gene3D G3DSA:3.40.50.360 35 211 2.7E-36 T 29-03-2018 IPR029039 Flavoprotein-like domain MC49_RS11960 9f6d4775d68d40ff62b9003c573816e0 165 Pfam PF05591 Type VI secretion system, VipA, VC_A0107 or Hcp2 8 159 5.1E-56 T 29-03-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 MC49_RS11960 9f6d4775d68d40ff62b9003c573816e0 165 PIRSF PIRSF028301 1 165 3.5E-60 T 29-03-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 MC49_RS11960 9f6d4775d68d40ff62b9003c573816e0 165 TIGRFAM TIGR03358 VI_chp_5: type VI secretion protein, VC_A0107 family 7 160 4.7E-56 T 29-03-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 MC49_RS12520 68629204b4c91dc637001545ab4b99b5 134 Pfam PF00460 Flagella basal body rod protein 7 36 2.4E-6 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 MC49_RS12520 68629204b4c91dc637001545ab4b99b5 134 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 87 132 5.8E-12 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain MC49_RS12520 68629204b4c91dc637001545ab4b99b5 134 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 29-03-2018 IPR019776 Flagellar basal body rod protein, conserved site MC49_RS12520 68629204b4c91dc637001545ab4b99b5 134 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 4 134 6.8E-50 T 29-03-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 MC49_RS15435 68f50b2efa305f3a5ddc8a8b304be94b 331 SUPERFAMILY SSF55347 149 312 5.61E-80 T 29-03-2018 MC49_RS15435 68f50b2efa305f3a5ddc8a8b304be94b 331 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 102 2.6E-41 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS15435 68f50b2efa305f3a5ddc8a8b304be94b 331 Gene3D G3DSA:3.40.50.720 1 159 2.0E-82 T 29-03-2018 MC49_RS15435 68f50b2efa305f3a5ddc8a8b304be94b 331 Gene3D G3DSA:3.30.360.10 160 314 1.9E-80 T 29-03-2018 MC49_RS15435 68f50b2efa305f3a5ddc8a8b304be94b 331 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 324 1.4E-136 T 29-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS15435 68f50b2efa305f3a5ddc8a8b304be94b 331 SUPERFAMILY SSF51735 3 166 1.88E-70 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS15435 68f50b2efa305f3a5ddc8a8b304be94b 331 PIRSF PIRSF000149 1 331 2.3E-134 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS15435 68f50b2efa305f3a5ddc8a8b304be94b 331 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 148 155 - T 29-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS15435 68f50b2efa305f3a5ddc8a8b304be94b 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 144 162 8.6E-48 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS15435 68f50b2efa305f3a5ddc8a8b304be94b 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 8.6E-48 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS15435 68f50b2efa305f3a5ddc8a8b304be94b 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 171 187 8.6E-48 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS15435 68f50b2efa305f3a5ddc8a8b304be94b 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 268 283 8.6E-48 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS15435 68f50b2efa305f3a5ddc8a8b304be94b 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 228 245 8.6E-48 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS15435 68f50b2efa305f3a5ddc8a8b304be94b 331 SMART SM00846 3 150 1.4E-100 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS15435 68f50b2efa305f3a5ddc8a8b304be94b 331 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 155 312 1.5E-70 T 29-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS07460 db17c3669787d94287c44b4b117556a3 420 SUPERFAMILY SSF52540 232 410 1.1E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS07460 db17c3669787d94287c44b4b117556a3 420 SUPERFAMILY SSF47413 6 62 8.89E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS07460 db17c3669787d94287c44b4b117556a3 420 TIGRFAM TIGR01526 nadR_NMN_Atrans: nicotinamide-nucleotide adenylyltransferase 66 395 6.0E-149 T 29-03-2018 IPR006417 Nicotinamide-nucleotide adenylyltransferase GO:0003677|GO:0006355|GO:0006810|GO:0019363 KEGG: 00760+2.7.7.1+2.7.1.22 MC49_RS07460 db17c3669787d94287c44b4b117556a3 420 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 67 136 9.9E-19 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MC49_RS07460 db17c3669787d94287c44b4b117556a3 420 Gene3D G3DSA:1.10.260.40 5 60 1.5E-9 T 29-03-2018 MC49_RS07460 db17c3669787d94287c44b4b117556a3 420 Gene3D G3DSA:3.40.50.620 61 232 5.1E-21 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS07460 db17c3669787d94287c44b4b117556a3 420 Pfam PF01381 Helix-turn-helix 7 58 1.1E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS07460 db17c3669787d94287c44b4b117556a3 420 SMART SM00530 6 62 1.3E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS07460 db17c3669787d94287c44b4b117556a3 420 SUPERFAMILY SSF52374 66 231 9.65E-21 T 29-03-2018 MC49_RS07460 db17c3669787d94287c44b4b117556a3 420 Gene3D G3DSA:3.40.50.300 233 399 6.1E-14 T 29-03-2018 MC49_RS07460 db17c3669787d94287c44b4b117556a3 420 PIRSF PIRSF004776 3 414 7.6E-196 T 29-03-2018 IPR016429 Bifunctional transcriptional regulator NadR GO:0045892 KEGG: 00760+2.7.7.1+2.7.1.22 MC49_RS07460 db17c3669787d94287c44b4b117556a3 420 Pfam PF13521 AAA domain 234 394 2.9E-33 T 29-03-2018 MC49_RS01815 68b863bae3027ca01d57797a68ae1b83 370 Gene3D G3DSA:3.40.50.2300 23 172 2.0E-35 T 29-03-2018 MC49_RS01815 68b863bae3027ca01d57797a68ae1b83 370 Pfam PF13458 Periplasmic binding protein 27 361 1.0E-62 T 29-03-2018 IPR028081 Leucine-binding protein domain MC49_RS01815 68b863bae3027ca01d57797a68ae1b83 370 Gene3D G3DSA:3.40.50.2300 173 351 6.7E-23 T 29-03-2018 MC49_RS01815 68b863bae3027ca01d57797a68ae1b83 370 SUPERFAMILY SSF53822 25 364 1.61E-89 T 29-03-2018 IPR028082 Periplasmic binding protein-like I MC49_RS01815 68b863bae3027ca01d57797a68ae1b83 370 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 278 291 2.0E-60 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 MC49_RS01815 68b863bae3027ca01d57797a68ae1b83 370 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 330 345 2.0E-60 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 MC49_RS01815 68b863bae3027ca01d57797a68ae1b83 370 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 68 86 2.0E-60 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 MC49_RS01815 68b863bae3027ca01d57797a68ae1b83 370 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 49 65 2.0E-60 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 MC49_RS01815 68b863bae3027ca01d57797a68ae1b83 370 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 27 43 2.0E-60 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 MC49_RS01815 68b863bae3027ca01d57797a68ae1b83 370 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 255 273 2.0E-60 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 MC49_RS01815 68b863bae3027ca01d57797a68ae1b83 370 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 89 99 2.0E-60 T 29-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 MC49_RS08640 67d2f965ef1f6a518674e36f60cccc39 347 SUPERFAMILY SSF53774 24 346 1.03E-100 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MC49_RS08640 67d2f965ef1f6a518674e36f60cccc39 347 SMART SM00870 25 341 1.3E-127 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MC49_RS08640 67d2f965ef1f6a518674e36f60cccc39 347 PIRSF PIRSF001220 21 347 7.7E-87 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MC49_RS08640 67d2f965ef1f6a518674e36f60cccc39 347 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 28 36 - T 29-03-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 MC49_RS08640 67d2f965ef1f6a518674e36f60cccc39 347 Gene3D G3DSA:3.40.50.1170 21 230 4.0E-59 T 29-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 MC49_RS08640 67d2f965ef1f6a518674e36f60cccc39 347 Gene3D G3DSA:3.40.50.40 234 346 3.0E-31 T 29-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 MC49_RS08640 67d2f965ef1f6a518674e36f60cccc39 347 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 104 114 - T 29-03-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 MC49_RS08640 67d2f965ef1f6a518674e36f60cccc39 347 PIRSF PIRSF500176 22 347 9.7E-79 T 29-03-2018 MC49_RS08640 67d2f965ef1f6a518674e36f60cccc39 347 Pfam PF00710 Asparaginase, N-terminal 26 214 4.5E-57 T 29-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 MC49_RS08640 67d2f965ef1f6a518674e36f60cccc39 347 PRINTS PR00139 Asparaginase/glutaminase family signature 281 299 5.2E-23 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MC49_RS08640 67d2f965ef1f6a518674e36f60cccc39 347 PRINTS PR00139 Asparaginase/glutaminase family signature 26 37 5.2E-23 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MC49_RS08640 67d2f965ef1f6a518674e36f60cccc39 347 PRINTS PR00139 Asparaginase/glutaminase family signature 103 121 5.2E-23 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MC49_RS08640 67d2f965ef1f6a518674e36f60cccc39 347 TIGRFAM TIGR00520 asnASE_II: L-asparaginase, type II 16 347 8.4E-145 T 29-03-2018 IPR004550 L-asparaginase, type II GO:0004067|GO:0006528 MC49_RS08505 1277b0adebc0413f6fb7b7060cee84d3 105 Pfam PF14330 Domain of unknown function (DUF4387) 6 102 1.1E-38 T 29-03-2018 IPR025496 Protein of unknown function DUF4387 MC49_RS06555 f338514b5aa7dd241b6f542adb00d287 529 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 8 529 3.9E-261 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MC49_RS06555 f338514b5aa7dd241b6f542adb00d287 529 Gene3D G3DSA:3.40.50.1380 1 196 6.6E-78 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain MC49_RS06555 f338514b5aa7dd241b6f542adb00d287 529 SUPERFAMILY SSF52335 7 197 2.35E-70 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain MC49_RS06555 f338514b5aa7dd241b6f542adb00d287 529 Gene3D G3DSA:3.40.140.20 375 519 1.8E-52 T 29-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MC49_RS06555 f338514b5aa7dd241b6f542adb00d287 529 SUPERFAMILY SSF53927 221 529 8.72E-130 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 MC49_RS06555 f338514b5aa7dd241b6f542adb00d287 529 SMART SM00798 137 461 2.1E-214 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MC49_RS06555 f338514b5aa7dd241b6f542adb00d287 529 Pfam PF02142 MGS-like domain 19 132 1.1E-29 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain MC49_RS06555 f338514b5aa7dd241b6f542adb00d287 529 Pfam PF01808 AICARFT/IMPCHase bienzyme 137 460 5.3E-119 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MC49_RS06555 f338514b5aa7dd241b6f542adb00d287 529 PIRSF PIRSF000414 1 529 4.1E-228 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MC49_RS06555 f338514b5aa7dd241b6f542adb00d287 529 SMART SM00851 19 132 3.8E-61 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain MC49_RS06555 f338514b5aa7dd241b6f542adb00d287 529 Gene3D G3DSA:3.40.140.20 225 374 1.1E-54 T 29-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MC49_RS06555 f338514b5aa7dd241b6f542adb00d287 529 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 7 529 45.233 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MC49_RS07885 f12686ce7f6af91f2fcdf05e394b05a2 1133 SUPERFAMILY SSF52540 368 817 5.1E-105 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS07885 f12686ce7f6af91f2fcdf05e394b05a2 1133 TIGRFAM TIGR01450 recC: exodeoxyribonuclease V, gamma subunit 2 1088 0.0 T 29-03-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 MC49_RS07885 f12686ce7f6af91f2fcdf05e394b05a2 1133 SUPERFAMILY SSF52540 1 350 6.9E-120 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS07885 f12686ce7f6af91f2fcdf05e394b05a2 1133 Gene3D G3DSA:1.10.486.10 445 653 2.2E-71 T 29-03-2018 MC49_RS07885 f12686ce7f6af91f2fcdf05e394b05a2 1133 Pfam PF04257 Exodeoxyribonuclease V, gamma subunit 1 810 2.8E-295 T 29-03-2018 MC49_RS07885 f12686ce7f6af91f2fcdf05e394b05a2 1133 Hamap MF_01486 RecBCD enzyme subunit RecC [recC]. 1 1127 21.02 T 29-03-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 MC49_RS07885 f12686ce7f6af91f2fcdf05e394b05a2 1133 SUPERFAMILY SSF52980 825 1124 6.97E-82 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MC49_RS07885 f12686ce7f6af91f2fcdf05e394b05a2 1133 Gene3D G3DSA:1.10.10.160 86 185 1.0E-31 T 29-03-2018 MC49_RS07885 f12686ce7f6af91f2fcdf05e394b05a2 1133 PIRSF PIRSF000980 1 1130 0.0 T 29-03-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 MC49_RS16255 bd9807777c2dd2c2701940894fd21f76 690 Gene3D G3DSA:1.20.58.310 9 109 2.8E-34 T 29-03-2018 MC49_RS16255 bd9807777c2dd2c2701940894fd21f76 690 Pfam PF13089 Polyphosphate kinase N-terminal domain 7 110 5.0E-32 T 29-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 MC49_RS16255 bd9807777c2dd2c2701940894fd21f76 690 Pfam PF13090 Polyphosphate kinase C-terminal domain 333 679 1.2E-141 T 29-03-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 MC49_RS16255 bd9807777c2dd2c2701940894fd21f76 690 SUPERFAMILY SSF140356 3 106 1.15E-32 T 29-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 MC49_RS16255 bd9807777c2dd2c2701940894fd21f76 690 PIRSF PIRSF015589 1 689 2.1E-241 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 MC49_RS16255 bd9807777c2dd2c2701940894fd21f76 690 Gene3D G3DSA:3.30.870.10 318 502 6.8E-24 T 29-03-2018 MC49_RS16255 bd9807777c2dd2c2701940894fd21f76 690 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 7 680 8.2E-252 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 MC49_RS16255 bd9807777c2dd2c2701940894fd21f76 690 Hamap MF_00347 Polyphosphate kinase [ppk]. 5 684 26.931 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 MC49_RS16255 bd9807777c2dd2c2701940894fd21f76 690 Pfam PF02503 Polyphosphate kinase middle domain 119 322 8.5E-43 T 29-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 MC49_RS16255 bd9807777c2dd2c2701940894fd21f76 690 SUPERFAMILY SSF56024 317 499 4.71E-54 T 29-03-2018 MC49_RS16255 bd9807777c2dd2c2701940894fd21f76 690 Gene3D G3DSA:3.30.1840.10 110 309 9.9E-51 T 29-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 MC49_RS16255 bd9807777c2dd2c2701940894fd21f76 690 SUPERFAMILY SSF143724 108 315 2.94E-58 T 29-03-2018 MC49_RS16255 bd9807777c2dd2c2701940894fd21f76 690 SUPERFAMILY SSF56024 503 685 1.59E-65 T 29-03-2018 MC49_RS16255 bd9807777c2dd2c2701940894fd21f76 690 Gene3D G3DSA:3.30.870.10 503 689 1.3E-35 T 29-03-2018 MC49_RS18080 d17cc828b2b779a0469b085a6657f154 202 Gene3D G3DSA:1.10.10.60 1 59 9.8E-16 T 29-03-2018 MC49_RS18080 d17cc828b2b779a0469b085a6657f154 202 SUPERFAMILY SSF48498 78 192 1.96E-27 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MC49_RS18080 d17cc828b2b779a0469b085a6657f154 202 ProSitePatterns PS01081 TetR-type HTH domain signature. 25 55 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MC49_RS18080 d17cc828b2b779a0469b085a6657f154 202 SUPERFAMILY SSF46689 3 79 1.08E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS18080 d17cc828b2b779a0469b085a6657f154 202 Gene3D G3DSA:1.10.357.10 60 193 4.2E-24 T 29-03-2018 MC49_RS18080 d17cc828b2b779a0469b085a6657f154 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 59 1.1E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS05925 b46e77f6a6cc325be177be663936f40b 493 Gene3D G3DSA:2.40.128.130 315 493 2.3E-29 T 29-03-2018 MC49_RS05925 b46e77f6a6cc325be177be663936f40b 493 SUPERFAMILY SSF103515 327 493 3.27E-30 T 29-03-2018 IPR005546 Autotransporter beta-domain MC49_RS05925 b46e77f6a6cc325be177be663936f40b 493 Pfam PF03797 Autotransporter beta-domain 354 493 9.0E-28 T 29-03-2018 IPR005546 Autotransporter beta-domain MC49_RS05925 b46e77f6a6cc325be177be663936f40b 493 SUPERFAMILY SSF51126 36 288 6.91E-25 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor MC49_RS05925 b46e77f6a6cc325be177be663936f40b 493 Pfam PF03212 Pertactin 167 287 2.9E-24 T 29-03-2018 IPR004899 Pertactin, central region MC49_RS05925 b46e77f6a6cc325be177be663936f40b 493 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 188 493 4.1E-61 T 29-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 MC49_RS05925 b46e77f6a6cc325be177be663936f40b 493 Gene3D G3DSA:2.160.20.20 11 291 8.4E-28 T 29-03-2018 IPR012332 P22 tailspike C-terminal domain-like MC49_RS04305 f0e5305a301ddb0b7f3363e7e0baefcc 277 SMART SM00062 34 257 2.3E-62 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MC49_RS04305 f0e5305a301ddb0b7f3363e7e0baefcc 277 Gene3D G3DSA:3.40.190.10 177 266 1.6E-9 T 29-03-2018 MC49_RS04305 f0e5305a301ddb0b7f3363e7e0baefcc 277 SUPERFAMILY SSF53850 6 256 5.79E-65 T 29-03-2018 MC49_RS04305 f0e5305a301ddb0b7f3363e7e0baefcc 277 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 35 255 2.6E-56 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MC49_RS04305 f0e5305a301ddb0b7f3363e7e0baefcc 277 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 58 71 - T 29-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 MC49_RS04305 f0e5305a301ddb0b7f3363e7e0baefcc 277 Gene3D G3DSA:3.40.190.10 23 176 5.9E-41 T 29-03-2018 MC49_RS00870 36f39da1ed22289f7f39c5647f94973c 149 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 149 89.651 T 29-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 MC49_RS00870 36f39da1ed22289f7f39c5647f94973c 149 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 147 2.4E-74 T 29-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 MC49_RS00870 36f39da1ed22289f7f39c5647f94973c 149 Pfam PF03477 ATP cone domain 50 136 3.2E-16 T 29-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 MC49_RS06030 e8717f3ed47954e46eb0b07a653f8924 305 Pfam PF00583 Acetyltransferase (GNAT) family 41 122 7.4E-15 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MC49_RS06030 e8717f3ed47954e46eb0b07a653f8924 305 Gene3D G3DSA:3.40.630.30 2 155 2.1E-25 T 29-03-2018 MC49_RS06030 e8717f3ed47954e46eb0b07a653f8924 305 Pfam PF09500 Putative thioesterase (yiiD_Cterm) 158 297 8.8E-49 T 29-03-2018 IPR012660 Thioesterase, putative MC49_RS06030 e8717f3ed47954e46eb0b07a653f8924 305 Gene3D G3DSA:3.10.129.10 156 301 1.6E-20 T 29-03-2018 MC49_RS06030 e8717f3ed47954e46eb0b07a653f8924 305 SUPERFAMILY SSF54637 155 297 2.02E-41 T 29-03-2018 IPR029069 HotDog domain MC49_RS06030 e8717f3ed47954e46eb0b07a653f8924 305 TIGRFAM TIGR02447 yiiD_Cterm: putative thioesterase domain 165 298 2.0E-46 T 29-03-2018 IPR012660 Thioesterase, putative MC49_RS06030 e8717f3ed47954e46eb0b07a653f8924 305 SUPERFAMILY SSF55729 2 147 2.19E-29 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS08910 f24565adffbac19f03f275a3aff25dd2 404 Pfam PF06792 Uncharacterised protein family (UPF0261) 8 400 3.3E-155 T 29-03-2018 IPR008322 Uncharacterised protein family UPF0261 MC49_RS08910 f24565adffbac19f03f275a3aff25dd2 404 PIRSF PIRSF033271 4 404 4.2E-177 T 29-03-2018 IPR008322 Uncharacterised protein family UPF0261 MC49_RS08910 f24565adffbac19f03f275a3aff25dd2 404 Hamap MF_00677 UPF0261 protein . 5 404 47.757 T 29-03-2018 IPR008322 Uncharacterised protein family UPF0261 MC49_RS18695 062edbeced020bad25f55a5140929052 152 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 1 151 3.4E-58 T 29-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 MC49_RS18695 062edbeced020bad25f55a5140929052 152 Gene3D G3DSA:2.10.260.10 80 128 0.025 T 29-03-2018 MC49_RS18695 062edbeced020bad25f55a5140929052 152 Gene3D G3DSA:2.10.260.10 3 44 0.0013 T 29-03-2018 MC49_RS18695 062edbeced020bad25f55a5140929052 152 Pfam PF02381 MraZ protein, putative antitoxin-like 1 75 1.9E-20 T 29-03-2018 IPR020603 MraZ domain MC49_RS18695 062edbeced020bad25f55a5140929052 152 Pfam PF02381 MraZ protein, putative antitoxin-like 77 136 5.4E-20 T 29-03-2018 IPR020603 MraZ domain MC49_RS18695 062edbeced020bad25f55a5140929052 152 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 138 4.0E-64 T 29-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 MC49_RS18695 062edbeced020bad25f55a5140929052 152 SUPERFAMILY SSF89447 1 134 1.78E-43 T 29-03-2018 MC49_RS18695 062edbeced020bad25f55a5140929052 152 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 152 53.59 T 29-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 MC49_RS14785 e21ef4f6ff8076cc6b1e2ec72bd7cc35 261 Pfam PF01965 DJ-1/PfpI family 35 193 6.9E-14 T 29-03-2018 IPR002818 DJ-1/PfpI MC49_RS14785 e21ef4f6ff8076cc6b1e2ec72bd7cc35 261 Gene3D G3DSA:3.40.50.880 29 260 5.2E-33 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MC49_RS14785 e21ef4f6ff8076cc6b1e2ec72bd7cc35 261 SUPERFAMILY SSF52317 34 214 1.37E-32 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MC49_RS09870 64a5c7f2488123d01d30222003c36acc 453 SMART SM00963 1 86 4.7E-37 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MC49_RS09870 64a5c7f2488123d01d30222003c36acc 453 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 269 282 - T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MC49_RS09870 64a5c7f2488123d01d30222003c36acc 453 Pfam PF00448 SRP54-type protein, GTPase domain 100 296 5.3E-74 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MC49_RS09870 64a5c7f2488123d01d30222003c36acc 453 SMART SM00382 99 247 1.1E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS09870 64a5c7f2488123d01d30222003c36acc 453 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 429 1.2E-178 T 29-03-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 MC49_RS09870 64a5c7f2488123d01d30222003c36acc 453 Gene3D G3DSA:3.40.50.300 92 297 6.3E-40 T 29-03-2018 MC49_RS09870 64a5c7f2488123d01d30222003c36acc 453 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 3.7E-22 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MC49_RS09870 64a5c7f2488123d01d30222003c36acc 453 Gene3D G3DSA:1.10.260.30 328 432 2.9E-38 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 MC49_RS09870 64a5c7f2488123d01d30222003c36acc 453 SUPERFAMILY SSF52540 42 353 1.7E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS09870 64a5c7f2488123d01d30222003c36acc 453 SMART SM00962 100 296 2.2E-116 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MC49_RS09870 64a5c7f2488123d01d30222003c36acc 453 Gene3D G3DSA:1.20.120.140 1 91 5.3E-30 T 29-03-2018 MC49_RS09870 64a5c7f2488123d01d30222003c36acc 453 SUPERFAMILY SSF47446 329 431 6.05E-38 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 MC49_RS09870 64a5c7f2488123d01d30222003c36acc 453 Pfam PF02978 Signal peptide binding domain 329 427 7.0E-33 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 MC49_RS09870 64a5c7f2488123d01d30222003c36acc 453 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 439 34.713 T 29-03-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 MC49_RS18650 d5600ffb13ea2da5ae5b68f4479a142f 357 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 185 345 9.8E-34 T 29-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 MC49_RS18650 d5600ffb13ea2da5ae5b68f4479a142f 357 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 8 354 33.965 T 29-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MC49_RS18650 d5600ffb13ea2da5ae5b68f4479a142f 357 Gene3D G3DSA:3.40.50.2000 176 348 3.3E-27 T 29-03-2018 MC49_RS18650 d5600ffb13ea2da5ae5b68f4479a142f 357 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 1 350 2.0E-109 T 29-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MC49_RS18650 d5600ffb13ea2da5ae5b68f4479a142f 357 Gene3D G3DSA:3.40.50.2000 1 175 2.4E-42 T 29-03-2018 MC49_RS18650 d5600ffb13ea2da5ae5b68f4479a142f 357 SUPERFAMILY SSF53756 7 355 3.14E-122 T 29-03-2018 MC49_RS18650 d5600ffb13ea2da5ae5b68f4479a142f 357 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 9 145 3.9E-46 T 29-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MC49_RS13920 968c5d7ec6dd44a178e29cfd7648e35d 360 SUPERFAMILY SSF75620 12 353 4.71E-136 T 29-03-2018 MC49_RS13920 968c5d7ec6dd44a178e29cfd7648e35d 360 Gene3D G3DSA:3.30.160.20 209 291 4.8E-33 T 29-03-2018 MC49_RS13920 968c5d7ec6dd44a178e29cfd7648e35d 360 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 5 357 40.892 T 29-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 MC49_RS13920 968c5d7ec6dd44a178e29cfd7648e35d 360 Pfam PF00472 RF-1 domain 216 321 1.6E-41 T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MC49_RS13920 968c5d7ec6dd44a178e29cfd7648e35d 360 Pfam PF03462 PCRF domain 12 203 7.7E-77 T 29-03-2018 IPR005139 Peptide chain release factor GO:0006415 MC49_RS13920 968c5d7ec6dd44a178e29cfd7648e35d 360 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 228 244 - T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MC49_RS13920 968c5d7ec6dd44a178e29cfd7648e35d 360 SMART SM00937 63 178 4.1E-69 T 29-03-2018 IPR005139 Peptide chain release factor GO:0006415 MC49_RS13920 968c5d7ec6dd44a178e29cfd7648e35d 360 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 1 358 5.0E-174 T 29-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 MC49_RS13920 968c5d7ec6dd44a178e29cfd7648e35d 360 Gene3D G3DSA:1.20.58.410 3 101 4.8E-19 T 29-03-2018 MC49_RS07345 42eb560b927cbd992ffd25fe3bf356ee 566 Gene3D G3DSA:3.40.50.300 349 561 4.4E-41 T 29-03-2018 MC49_RS07345 42eb560b927cbd992ffd25fe3bf356ee 566 Pfam PF00005 ABC transporter 376 509 6.0E-20 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS07345 42eb560b927cbd992ffd25fe3bf356ee 566 ProSitePatterns PS00211 ABC transporters family signature. 481 495 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS07345 42eb560b927cbd992ffd25fe3bf356ee 566 Pfam PF06472 ABC transporter transmembrane region 2 3 291 1.1E-46 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MC49_RS07345 42eb560b927cbd992ffd25fe3bf356ee 566 SUPERFAMILY SSF90123 6 340 1.15E-17 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MC49_RS07345 42eb560b927cbd992ffd25fe3bf356ee 566 SMART SM00382 385 555 2.4E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS07345 42eb560b927cbd992ffd25fe3bf356ee 566 Gene3D G3DSA:1.20.1560.10 1 348 1.1E-32 T 29-03-2018 MC49_RS07345 42eb560b927cbd992ffd25fe3bf356ee 566 SUPERFAMILY SSF52540 372 552 6.15E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS13110 f8e8ac5424159c03da848bffe2c59658 251 Gene3D G3DSA:2.60.40.1080 161 251 1.9E-18 T 29-03-2018 MC49_RS13110 f8e8ac5424159c03da848bffe2c59658 251 SMART SM00635 165 245 1.2E-16 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 MC49_RS13110 f8e8ac5424159c03da848bffe2c59658 251 Pfam PF02368 Bacterial Ig-like domain (group 2) 166 246 2.9E-13 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 MC49_RS13110 f8e8ac5424159c03da848bffe2c59658 251 SUPERFAMILY SSF49373 162 248 1.02E-9 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS08490 adaa72d3442be293993423d193076fd7 481 Gene3D G3DSA:3.20.20.240 1 416 2.2E-110 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 MC49_RS08490 adaa72d3442be293993423d193076fd7 481 PIRSF PIRSF001495 1 481 3.3E-230 T 29-03-2018 IPR006396 Glutamate mutase epsilon subunit GO:0019670|GO:0050097 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 MC49_RS08490 adaa72d3442be293993423d193076fd7 481 SUPERFAMILY SSF51703 1 481 1.1E-198 T 29-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 MC49_RS08490 adaa72d3442be293993423d193076fd7 481 TIGRFAM TIGR01503 MthylAspMut_E: methylaspartate mutase, E subunit 3 481 6.2E-243 T 29-03-2018 IPR006396 Glutamate mutase epsilon subunit GO:0019670|GO:0050097 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 MC49_RS08490 adaa72d3442be293993423d193076fd7 481 Pfam PF06368 Methylaspartate mutase E chain (MutE) 45 481 3.1E-212 T 29-03-2018 IPR006396 Glutamate mutase epsilon subunit GO:0019670|GO:0050097 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 MC49_RS08490 adaa72d3442be293993423d193076fd7 481 Hamap MF_01923 Glutamate mutase epsilon subunit [glmE]. 2 481 53.814 T 29-03-2018 IPR006396 Glutamate mutase epsilon subunit GO:0019670|GO:0050097 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 MC49_RS08490 adaa72d3442be293993423d193076fd7 481 Gene3D G3DSA:3.90.970.10 417 481 6.8E-28 T 29-03-2018 IPR014714 Glutamate mutase E subunit, C-terminal domain GO:0016866|GO:0019670|GO:0031419 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 MC49_RS14905 b6181a0558aabae4f224542e404d9ab0 360 Gene3D G3DSA:3.40.10.10 1 73 3.9E-16 T 29-03-2018 IPR035451 Ada-like domain MC49_RS14905 b6181a0558aabae4f224542e404d9ab0 360 Gene3D G3DSA:1.10.10.60 74 149 1.1E-13 T 29-03-2018 MC49_RS14905 b6181a0558aabae4f224542e404d9ab0 360 Gene3D G3DSA:1.10.10.60 150 187 0.048 T 29-03-2018 MC49_RS14905 b6181a0558aabae4f224542e404d9ab0 360 PIRSF PIRSF000409 1 359 7.0E-123 T 29-03-2018 IPR016221 Bifunctional regulatory protein Ada MC49_RS14905 b6181a0558aabae4f224542e404d9ab0 360 Gene3D G3DSA:3.30.160.70 188 271 5.7E-22 T 29-03-2018 MC49_RS14905 b6181a0558aabae4f224542e404d9ab0 360 Pfam PF02805 Metal binding domain of Ada 11 72 2.7E-21 T 29-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 MC49_RS14905 b6181a0558aabae4f224542e404d9ab0 360 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 197 254 1.6E-4 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MC49_RS14905 b6181a0558aabae4f224542e404d9ab0 360 SMART SM00342 103 186 4.6E-12 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MC49_RS14905 b6181a0558aabae4f224542e404d9ab0 360 SUPERFAMILY SSF57884 1 92 3.14E-20 T 29-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 MC49_RS14905 b6181a0558aabae4f224542e404d9ab0 360 Gene3D G3DSA:1.10.10.10 272 358 4.9E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS14905 b6181a0558aabae4f224542e404d9ab0 360 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 275 354 1.3E-30 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MC49_RS14905 b6181a0558aabae4f224542e404d9ab0 360 SUPERFAMILY SSF46767 273 354 5.36E-29 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MC49_RS14905 b6181a0558aabae4f224542e404d9ab0 360 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 324 330 - T 29-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MC49_RS14905 b6181a0558aabae4f224542e404d9ab0 360 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 274 353 1.5E-33 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MC49_RS14905 b6181a0558aabae4f224542e404d9ab0 360 SUPERFAMILY SSF46689 87 137 4.23E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS14905 b6181a0558aabae4f224542e404d9ab0 360 Pfam PF12833 Helix-turn-helix domain 110 187 2.2E-16 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MC49_RS14905 b6181a0558aabae4f224542e404d9ab0 360 SUPERFAMILY SSF53155 194 272 6.08E-22 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MC49_RS15785 3c374d509a6ad28ec423c46a98ed828a 78 Pfam PF04728 Lipoprotein leucine-zipper 26 78 7.3E-24 T 29-03-2018 IPR006817 Lipoprotein leucine-zipper GO:0019867 MC49_RS15785 3c374d509a6ad28ec423c46a98ed828a 78 PIRSF PIRSF002855 1 78 7.7E-29 T 29-03-2018 IPR016367 Murein-lipoprotein MC49_RS15785 3c374d509a6ad28ec423c46a98ed828a 78 SUPERFAMILY SSF58042 22 77 3.14E-21 T 29-03-2018 MC49_RS15785 3c374d509a6ad28ec423c46a98ed828a 78 Gene3D G3DSA:1.20.5.190 22 72 1.1E-13 T 29-03-2018 MC49_RS02035 68ea06cc2de9942b1f0e28502f7778b7 577 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 45 161 8.6E-24 T 29-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS02035 68ea06cc2de9942b1f0e28502f7778b7 577 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 224 235 - T 29-03-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS02035 68ea06cc2de9942b1f0e28502f7778b7 577 Gene3D G3DSA:1.10.645.10 386 544 3.0E-33 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS02035 68ea06cc2de9942b1f0e28502f7778b7 577 Gene3D G3DSA:1.10.645.10 184 371 3.8E-43 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS02035 68ea06cc2de9942b1f0e28502f7778b7 577 Pfam PF00374 Nickel-dependent hydrogenase 226 294 2.5E-12 T 29-03-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 MC49_RS02035 68ea06cc2de9942b1f0e28502f7778b7 577 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 96 141 2.0E-16 T 29-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS02035 68ea06cc2de9942b1f0e28502f7778b7 577 SUPERFAMILY SSF143243 19 202 2.48E-45 T 29-03-2018 MC49_RS02035 68ea06cc2de9942b1f0e28502f7778b7 577 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 468 545 4.2E-11 T 29-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS02035 68ea06cc2de9942b1f0e28502f7778b7 577 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 304 472 3.9E-39 T 29-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS02035 68ea06cc2de9942b1f0e28502f7778b7 577 SUPERFAMILY SSF56762 201 545 7.72E-110 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS10810 417b04661e55c851c1534de3e936e29c 193 Pfam PF00692 dUTPase 80 184 9.9E-9 T 29-03-2018 IPR029054 dUTPase-like MC49_RS10810 417b04661e55c851c1534de3e936e29c 193 SUPERFAMILY SSF51283 1 192 5.89E-59 T 29-03-2018 IPR029054 dUTPase-like MC49_RS10810 417b04661e55c851c1534de3e936e29c 193 Hamap MF_00146 dCTP deaminase [dcd]. 1 190 33.518 T 29-03-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 MC49_RS10810 417b04661e55c851c1534de3e936e29c 193 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 2 190 3.8E-67 T 29-03-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 MC49_RS10810 417b04661e55c851c1534de3e936e29c 193 Gene3D G3DSA:2.70.40.10 2 168 9.4E-44 T 29-03-2018 MC49_RS07370 7c853ff8bbbc8c559cdfac71aeb9fa1c 531 Gene3D G3DSA:3.10.105.10 290 476 4.7E-40 T 29-03-2018 MC49_RS07370 7c853ff8bbbc8c559cdfac71aeb9fa1c 531 Gene3D G3DSA:3.90.76.10 58 150 1.1E-21 T 29-03-2018 MC49_RS07370 7c853ff8bbbc8c559cdfac71aeb9fa1c 531 Gene3D G3DSA:3.40.190.10 151 289 1.5E-27 T 29-03-2018 MC49_RS07370 7c853ff8bbbc8c559cdfac71aeb9fa1c 531 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 78 431 1.1E-76 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain MC49_RS07370 7c853ff8bbbc8c559cdfac71aeb9fa1c 531 SUPERFAMILY SSF53850 31 504 1.14E-98 T 29-03-2018 MC49_RS07370 7c853ff8bbbc8c559cdfac71aeb9fa1c 531 PIRSF PIRSF002741 1 518 5.0E-74 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MC49_RS04025 f3aba02f4d9db6a20c39ad23d33c14ca 149 Gene3D G3DSA:1.10.1660.10 58 140 2.6E-22 T 29-03-2018 MC49_RS04025 f3aba02f4d9db6a20c39ad23d33c14ca 149 SMART SM00422 2 71 1.3E-31 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MC49_RS04025 f3aba02f4d9db6a20c39ad23d33c14ca 149 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 3 14 8.1E-13 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MC49_RS04025 f3aba02f4d9db6a20c39ad23d33c14ca 149 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 38 58 8.1E-13 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MC49_RS04025 f3aba02f4d9db6a20c39ad23d33c14ca 149 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 27 8.1E-13 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MC49_RS04025 f3aba02f4d9db6a20c39ad23d33c14ca 149 SUPERFAMILY SSF46955 2 121 1.61E-33 T 29-03-2018 IPR009061 Putative DNA-binding domain MC49_RS04025 f3aba02f4d9db6a20c39ad23d33c14ca 149 Pfam PF13411 MerR HTH family regulatory protein 2 69 1.8E-21 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MC49_RS04025 f3aba02f4d9db6a20c39ad23d33c14ca 149 Gene3D G3DSA:1.10.1660.10 1 57 4.2E-25 T 29-03-2018 MC49_RS04025 f3aba02f4d9db6a20c39ad23d33c14ca 149 TIGRFAM TIGR02043 ZntR: Zn(II)-responsive transcriptional regulator 1 131 1.8E-62 T 29-03-2018 IPR011788 Zn(II)-responsive transcriptional regulator GO:0003677|GO:0006351|GO:0008270 MC49_RS04025 f3aba02f4d9db6a20c39ad23d33c14ca 149 ProSitePatterns PS00552 MerR-type HTH domain signature. 5 27 - T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MC49_RS05370 8c56c7b4dc226c6eeb7aad0a9998c39b 315 SUPERFAMILY SSF103481 198 300 1.11E-13 T 29-03-2018 MC49_RS05370 8c56c7b4dc226c6eeb7aad0a9998c39b 315 SUPERFAMILY SSF103481 53 147 3.79E-7 T 29-03-2018 MC49_RS05370 8c56c7b4dc226c6eeb7aad0a9998c39b 315 Pfam PF00892 EamA-like transporter family 10 143 3.6E-11 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MC49_RS05370 8c56c7b4dc226c6eeb7aad0a9998c39b 315 Pfam PF00892 EamA-like transporter family 161 295 2.8E-20 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MC49_RS06980 17bdf8826d857df8e2445fb36f4dd5c8 327 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 141 162 - T 29-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 MC49_RS06980 17bdf8826d857df8e2445fb36f4dd5c8 327 Pfam PF00107 Zinc-binding dehydrogenase 152 258 1.5E-28 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MC49_RS06980 17bdf8826d857df8e2445fb36f4dd5c8 327 Gene3D G3DSA:3.40.50.720 138 311 1.6E-29 T 29-03-2018 MC49_RS06980 17bdf8826d857df8e2445fb36f4dd5c8 327 SUPERFAMILY SSF51735 112 273 1.38E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS06980 17bdf8826d857df8e2445fb36f4dd5c8 327 SUPERFAMILY SSF50129 7 145 1.49E-34 T 29-03-2018 IPR011032 GroES-like MC49_RS06980 17bdf8826d857df8e2445fb36f4dd5c8 327 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 87 1.5E-8 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MC49_RS06980 17bdf8826d857df8e2445fb36f4dd5c8 327 SMART SM00829 11 325 2.1E-24 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MC49_RS06980 17bdf8826d857df8e2445fb36f4dd5c8 327 Gene3D G3DSA:3.90.180.10 2 137 2.0E-33 T 29-03-2018 MC49_RS18950 819b44d7ceff4ff24811cb1903f1dbb4 183 Pfam PF01292 Prokaryotic cytochrome b561 9 180 7.2E-27 T 29-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 MC49_RS18950 819b44d7ceff4ff24811cb1903f1dbb4 183 Gene3D G3DSA:1.20.950.20 1 182 4.0E-32 T 29-03-2018 MC49_RS18950 819b44d7ceff4ff24811cb1903f1dbb4 183 SUPERFAMILY SSF81342 4 180 7.22E-35 T 29-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 MC49_RS01560 345be0ddf3b99400821055f8f5189c90 322 Gene3D G3DSA:3.10.580.10 199 320 2.5E-22 T 29-03-2018 MC49_RS01560 345be0ddf3b99400821055f8f5189c90 322 SUPERFAMILY SSF53697 12 319 2.02E-68 T 29-03-2018 MC49_RS01560 345be0ddf3b99400821055f8f5189c90 322 Pfam PF00571 CBS domain 268 319 2.8E-6 T 29-03-2018 IPR000644 CBS domain MC49_RS01560 345be0ddf3b99400821055f8f5189c90 322 Pfam PF00571 CBS domain 200 254 2.5E-5 T 29-03-2018 IPR000644 CBS domain MC49_RS01560 345be0ddf3b99400821055f8f5189c90 322 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 44 312 3.1E-123 T 29-03-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 MC49_RS01560 345be0ddf3b99400821055f8f5189c90 322 PIRSF PIRSF004692 1 322 5.1E-134 T 29-03-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 MC49_RS01560 345be0ddf3b99400821055f8f5189c90 322 Gene3D G3DSA:3.40.50.10490 2 198 2.0E-56 T 29-03-2018 MC49_RS01560 345be0ddf3b99400821055f8f5189c90 322 Pfam PF01380 SIS domain 40 171 3.1E-33 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MC49_RS13935 726bd17d913d159b5ac30b5491a78b93 283 Pfam PF00793 DAHP synthetase I family 9 274 8.2E-67 T 29-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 MC49_RS13935 726bd17d913d159b5ac30b5491a78b93 283 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 18 275 2.1E-118 T 29-03-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 MC49_RS13935 726bd17d913d159b5ac30b5491a78b93 283 SUPERFAMILY SSF51569 3 278 1.19E-103 T 29-03-2018 MC49_RS13935 726bd17d913d159b5ac30b5491a78b93 283 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 13 277 49.374 T 29-03-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 MC49_RS13935 726bd17d913d159b5ac30b5491a78b93 283 Gene3D G3DSA:3.20.20.70 17 279 3.5E-67 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS16950 315458f168708154ce0dce9e0af38503 455 Pfam PF08328 Adenylosuccinate lyase C-terminal 331 445 1.9E-53 T 29-03-2018 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234 MC49_RS16950 315458f168708154ce0dce9e0af38503 455 Gene3D G3DSA:1.10.275.10 1 117 1.8E-44 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal MC49_RS16950 315458f168708154ce0dce9e0af38503 455 PRINTS PR00149 Fumarate lyase superfamily signature 251 278 5.6E-17 T 29-03-2018 IPR000362 Fumarate lyase family MC49_RS16950 315458f168708154ce0dce9e0af38503 455 PRINTS PR00149 Fumarate lyase superfamily signature 117 135 5.6E-17 T 29-03-2018 IPR000362 Fumarate lyase family MC49_RS16950 315458f168708154ce0dce9e0af38503 455 PRINTS PR00149 Fumarate lyase superfamily signature 294 310 5.6E-17 T 29-03-2018 IPR000362 Fumarate lyase family MC49_RS16950 315458f168708154ce0dce9e0af38503 455 PRINTS PR00149 Fumarate lyase superfamily signature 163 181 5.6E-17 T 29-03-2018 IPR000362 Fumarate lyase family MC49_RS16950 315458f168708154ce0dce9e0af38503 455 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 12 454 2.9E-149 T 29-03-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MC49_RS16950 315458f168708154ce0dce9e0af38503 455 ProSitePatterns PS00163 Fumarate lyases signature. 294 303 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 MC49_RS16950 315458f168708154ce0dce9e0af38503 455 Gene3D G3DSA:1.20.200.10 118 390 4.0E-83 T 29-03-2018 MC49_RS16950 315458f168708154ce0dce9e0af38503 455 Pfam PF00206 Lyase 14 312 1.6E-75 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal MC49_RS16950 315458f168708154ce0dce9e0af38503 455 SUPERFAMILY SSF48557 4 446 6.28E-105 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 MC49_RS16950 315458f168708154ce0dce9e0af38503 455 Gene3D G3DSA:1.10.40.30 391 445 1.7E-31 T 29-03-2018 MC49_RS15690 eef21589c1ee7440e7cedc5c630f63d4 215 Pfam PF00929 Exonuclease 20 191 3.8E-32 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MC49_RS15690 eef21589c1ee7440e7cedc5c630f63d4 215 SUPERFAMILY SSF53098 8 207 2.7E-55 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MC49_RS15690 eef21589c1ee7440e7cedc5c630f63d4 215 SMART SM00479 18 203 2.5E-30 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MC49_RS15690 eef21589c1ee7440e7cedc5c630f63d4 215 TIGRFAM TIGR01298 RNaseT: ribonuclease T 10 208 1.0E-101 T 29-03-2018 IPR005987 Ribonuclease T GO:0004540|GO:0006396 MC49_RS15690 eef21589c1ee7440e7cedc5c630f63d4 215 Hamap MF_00157 Ribonuclease T [rnt]. 1 215 109.174 T 29-03-2018 IPR005987 Ribonuclease T GO:0004540|GO:0006396 MC49_RS15690 eef21589c1ee7440e7cedc5c630f63d4 215 Gene3D G3DSA:3.30.420.10 9 213 9.4E-29 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MC49_RS07480 845ef04315711618610228ed78e31215 101 ProDom PD012582 REPRESSOR TRANSCRIPTION TRP OPERON DNA-BINDING REGULATION HOMOLOG AROH FOR TRYPTOPHAN 10 93 2.0E-30 T 29-03-2018 IPR013335 Trp repressor, bacterial GO:0006355 MC49_RS07480 845ef04315711618610228ed78e31215 101 PIRSF PIRSF003196 1 101 4.3E-40 T 29-03-2018 IPR013335 Trp repressor, bacterial GO:0006355 MC49_RS07480 845ef04315711618610228ed78e31215 101 SUPERFAMILY SSF48295 3 96 6.28E-29 T 29-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 MC49_RS07480 845ef04315711618610228ed78e31215 101 Gene3D G3DSA:1.10.1270.10 1 100 1.7E-21 T 29-03-2018 MC49_RS07480 845ef04315711618610228ed78e31215 101 TIGRFAM TIGR01321 TrpR: trp operon repressor 7 96 1.5E-34 T 29-03-2018 IPR013335 Trp repressor, bacterial GO:0006355 MC49_RS07480 845ef04315711618610228ed78e31215 101 Hamap MF_00475 Trp operon repressor [trpR]. 7 100 23.607 T 29-03-2018 IPR013335 Trp repressor, bacterial GO:0006355 MC49_RS07480 845ef04315711618610228ed78e31215 101 Pfam PF01371 Trp repressor protein 10 95 1.5E-30 T 29-03-2018 IPR000831 Trp repressor GO:0003700|GO:0005622|GO:0006355 MC49_RS17015 0cee985c28ead0e8ac8fe4569adbbbe5 1146 Gene3D G3DSA:3.40.50.300 793 952 4.9E-25 T 29-03-2018 MC49_RS17015 0cee985c28ead0e8ac8fe4569adbbbe5 1146 Pfam PF00271 Helicase conserved C-terminal domain 801 905 1.5E-17 T 29-03-2018 IPR001650 Helicase, C-terminal MC49_RS17015 0cee985c28ead0e8ac8fe4569adbbbe5 1146 Pfam PF03461 TRCF domain 1005 1097 5.3E-26 T 29-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 MC49_RS17015 0cee985c28ead0e8ac8fe4569adbbbe5 1146 SMART SM00487 596 792 6.7E-35 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MC49_RS17015 0cee985c28ead0e8ac8fe4569adbbbe5 1146 SUPERFAMILY SSF52540 7 339 2.66E-99 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS17015 0cee985c28ead0e8ac8fe4569adbbbe5 1146 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 145 1078 0.0 T 29-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 MC49_RS17015 0cee985c28ead0e8ac8fe4569adbbbe5 1146 SUPERFAMILY SSF52540 778 986 2.05E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS17015 0cee985c28ead0e8ac8fe4569adbbbe5 1146 Pfam PF02559 CarD-like/TRCF domain 476 571 8.6E-26 T 29-03-2018 IPR003711 CarD-like/TRCF domain MC49_RS17015 0cee985c28ead0e8ac8fe4569adbbbe5 1146 Pfam PF00270 DEAD/DEAH box helicase 601 761 1.1E-20 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MC49_RS17015 0cee985c28ead0e8ac8fe4569adbbbe5 1146 SMART SM00490 822 906 8.6E-18 T 29-03-2018 IPR001650 Helicase, C-terminal MC49_RS17015 0cee985c28ead0e8ac8fe4569adbbbe5 1146 SUPERFAMILY SSF52540 519 779 2.02E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS17015 0cee985c28ead0e8ac8fe4569adbbbe5 1146 SUPERFAMILY SSF52540 350 462 2.07E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS17015 0cee985c28ead0e8ac8fe4569adbbbe5 1146 Gene3D G3DSA:3.30.2060.10 130 196 0.0013 T 29-03-2018 MC49_RS17015 0cee985c28ead0e8ac8fe4569adbbbe5 1146 SMART SM01058 475 572 2.3E-51 T 29-03-2018 IPR003711 CarD-like/TRCF domain MC49_RS17015 0cee985c28ead0e8ac8fe4569adbbbe5 1146 SMART SM00982 1004 1104 1.7E-46 T 29-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 MC49_RS17015 0cee985c28ead0e8ac8fe4569adbbbe5 1146 SUPERFAMILY SSF141259 467 544 3.79E-24 T 29-03-2018 IPR003711 CarD-like/TRCF domain MC49_RS17015 0cee985c28ead0e8ac8fe4569adbbbe5 1146 Gene3D G3DSA:3.40.50.300 541 792 1.9E-42 T 29-03-2018 MC49_RS17015 0cee985c28ead0e8ac8fe4569adbbbe5 1146 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 31 1134 29.069 T 29-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 MC49_RS17015 0cee985c28ead0e8ac8fe4569adbbbe5 1146 SUPERFAMILY SSF143517 990 1142 1.83E-42 T 29-03-2018 MC49_RS03415 0fd029ccf7800aecde8698d9b778a766 649 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 103 596 7.5E-247 T 29-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 MC49_RS03415 0fd029ccf7800aecde8698d9b778a766 649 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 191 323 8.0E-46 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MC49_RS03415 0fd029ccf7800aecde8698d9b778a766 649 SUPERFAMILY SSF140990 405 604 4.84E-74 T 29-03-2018 MC49_RS03415 0fd029ccf7800aecde8698d9b778a766 649 Pfam PF01434 Peptidase family M41 384 594 3.6E-82 T 29-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 MC49_RS03415 0fd029ccf7800aecde8698d9b778a766 649 ProSitePatterns PS00674 AAA-protein family signature. 294 312 - T 29-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 MC49_RS03415 0fd029ccf7800aecde8698d9b778a766 649 SUPERFAMILY SSF52540 144 394 2.07E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS03415 0fd029ccf7800aecde8698d9b778a766 649 Pfam PF06480 FtsH Extracellular 8 96 5.1E-14 T 29-03-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 MC49_RS03415 0fd029ccf7800aecde8698d9b778a766 649 SMART SM00382 187 326 1.9E-26 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS03415 0fd029ccf7800aecde8698d9b778a766 649 Gene3D G3DSA:1.10.8.60 335 417 9.1E-25 T 29-03-2018 MC49_RS03415 0fd029ccf7800aecde8698d9b778a766 649 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 6 617 37.368 T 29-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 MC49_RS03415 0fd029ccf7800aecde8698d9b778a766 649 Gene3D G3DSA:3.40.50.300 131 334 4.9E-63 T 29-03-2018 MC49_RS14515 edce076b0512bd88686db8aedaf5211e 715 Gene3D G3DSA:2.170.130.10 25 165 3.4E-28 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MC49_RS14515 edce076b0512bd88686db8aedaf5211e 715 Pfam PF00593 TonB dependent receptor 213 714 1.8E-41 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MC49_RS14515 edce076b0512bd88686db8aedaf5211e 715 Pfam PF07715 TonB-dependent Receptor Plug Domain 48 155 4.3E-20 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MC49_RS14515 edce076b0512bd88686db8aedaf5211e 715 Gene3D G3DSA:2.40.170.20 166 715 7.5E-56 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MC49_RS14515 edce076b0512bd88686db8aedaf5211e 715 SUPERFAMILY SSF56935 38 715 1.36E-88 T 29-03-2018 MC49_RS14515 edce076b0512bd88686db8aedaf5211e 715 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 42 - T 29-03-2018 IPR010916 TonB box, conserved site MC49_RS03620 e16e82f73d2a7b370729d2b1530747d4 385 Pfam PF13484 4Fe-4S double cluster binding domain 198 262 1.0E-18 T 29-03-2018 MC49_RS03620 e16e82f73d2a7b370729d2b1530747d4 385 Gene3D G3DSA:3.30.70.20 126 205 6.9E-4 T 29-03-2018 MC49_RS03620 e16e82f73d2a7b370729d2b1530747d4 385 Pfam PF08331 Domain of unknown function (DUF1730) 62 146 6.6E-25 T 29-03-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 MC49_RS03620 e16e82f73d2a7b370729d2b1530747d4 385 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 7 321 52.197 T 29-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 MC49_RS03620 e16e82f73d2a7b370729d2b1530747d4 385 Gene3D G3DSA:3.30.70.20 206 378 5.6E-11 T 29-03-2018 MC49_RS03620 e16e82f73d2a7b370729d2b1530747d4 385 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 199 210 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MC49_RS03620 e16e82f73d2a7b370729d2b1530747d4 385 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 14 354 1.3E-152 T 29-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 MC49_RS03620 e16e82f73d2a7b370729d2b1530747d4 385 SUPERFAMILY SSF46548 145 262 2.56E-19 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MC49_RS04665 a3b944a86f1f98b62d718581cb2719e4 817 Gene3D G3DSA:2.40.40.20 680 817 2.4E-35 T 29-03-2018 MC49_RS04665 a3b944a86f1f98b62d718581cb2719e4 817 TIGRFAM TIGR02166 dmsA_ynfE: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family 14 817 0.0 T 29-03-2018 IPR011888 Anaerobic dimethyl sulphoxide reductase, subunit A, DmsA/YnfE GO:0009389|GO:0030151|GO:0051539|GO:0055114 MC49_RS04665 a3b944a86f1f98b62d718581cb2719e4 817 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 14 46 1.2E-4 T 29-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal MC49_RS04665 a3b944a86f1f98b62d718581cb2719e4 817 Gene3D G3DSA:3.40.228.10 613 679 2.3E-13 T 29-03-2018 MC49_RS04665 a3b944a86f1f98b62d718581cb2719e4 817 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 734 761 - T 29-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 MC49_RS04665 a3b944a86f1f98b62d718581cb2719e4 817 SUPERFAMILY SSF50692 644 817 1.54E-38 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain MC49_RS04665 a3b944a86f1f98b62d718581cb2719e4 817 SMART SM00926 59 119 1.4E-9 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS04665 a3b944a86f1f98b62d718581cb2719e4 817 Gene3D G3DSA:3.90.55.10 542 612 1.3E-23 T 29-03-2018 MC49_RS04665 a3b944a86f1f98b62d718581cb2719e4 817 Pfam PF00384 Molybdopterin oxidoreductase 122 579 5.9E-108 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS04665 a3b944a86f1f98b62d718581cb2719e4 817 SUPERFAMILY SSF53706 60 699 1.57E-177 T 29-03-2018 MC49_RS04665 a3b944a86f1f98b62d718581cb2719e4 817 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 64 82 - T 29-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 MC49_RS04665 a3b944a86f1f98b62d718581cb2719e4 817 Pfam PF01568 Molydopterin dinucleotide binding domain 698 809 3.9E-28 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 MC49_RS04665 a3b944a86f1f98b62d718581cb2719e4 817 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 59 119 9.0E-17 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS04665 a3b944a86f1f98b62d718581cb2719e4 817 Gene3D G3DSA:3.40.228.10 209 492 1.8E-64 T 29-03-2018 MC49_RS04665 a3b944a86f1f98b62d718581cb2719e4 817 Gene3D G3DSA:2.20.25.90 52 124 6.5E-19 T 29-03-2018 MC49_RS04665 a3b944a86f1f98b62d718581cb2719e4 817 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 520 537 - T 29-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 MC49_RS05625 6ce867fee52ead97273f3b322c22079d 312 Hamap MF_01601 ADP-L-glycero-D-manno-heptose-6-epimerase [hldD]. 1 311 49.173 T 29-03-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 MC49_RS05625 6ce867fee52ead97273f3b322c22079d 312 TIGRFAM TIGR02197 heptose_epim: ADP-glyceromanno-heptose 6-epimerase 2 310 6.4E-135 T 29-03-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 MC49_RS05625 6ce867fee52ead97273f3b322c22079d 312 Gene3D G3DSA:3.90.25.10 183 312 1.2E-18 T 29-03-2018 MC49_RS05625 6ce867fee52ead97273f3b322c22079d 312 SUPERFAMILY SSF51735 1 308 6.53E-63 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS05625 6ce867fee52ead97273f3b322c22079d 312 Pfam PF01370 NAD dependent epimerase/dehydratase family 2 236 1.4E-47 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MC49_RS05625 6ce867fee52ead97273f3b322c22079d 312 Gene3D G3DSA:3.40.50.720 1 182 4.7E-23 T 29-03-2018 MC49_RS18660 12b268a0a0a0d3d1a7b1e1bd26a61941 438 Gene3D G3DSA:3.90.190.20 299 433 3.3E-34 T 29-03-2018 MC49_RS18660 12b268a0a0a0d3d1a7b1e1bd26a61941 438 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 9 434 9.7E-126 T 29-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MC49_RS18660 12b268a0a0a0d3d1a7b1e1bd26a61941 438 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 7 436 34.009 T 29-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MC49_RS18660 12b268a0a0a0d3d1a7b1e1bd26a61941 438 Pfam PF02875 Mur ligase family, glutamate ligase domain 300 370 3.7E-9 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MC49_RS18660 12b268a0a0a0d3d1a7b1e1bd26a61941 438 Pfam PF08245 Mur ligase middle domain 110 279 8.0E-24 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MC49_RS18660 12b268a0a0a0d3d1a7b1e1bd26a61941 438 SUPERFAMILY SSF53623 95 296 5.89E-53 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MC49_RS18660 12b268a0a0a0d3d1a7b1e1bd26a61941 438 Gene3D G3DSA:3.40.50.720 1 94 1.7E-13 T 29-03-2018 MC49_RS18660 12b268a0a0a0d3d1a7b1e1bd26a61941 438 Gene3D G3DSA:3.40.1190.10 95 298 4.8E-54 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MC49_RS18660 12b268a0a0a0d3d1a7b1e1bd26a61941 438 SUPERFAMILY SSF51984 3 94 8.24E-22 T 29-03-2018 MC49_RS18660 12b268a0a0a0d3d1a7b1e1bd26a61941 438 SUPERFAMILY SSF53244 298 436 8.24E-49 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MC49_RS06465 97a6d20b6debecf3cabc274de83d00c7 66 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 66 2.5E-18 T 29-03-2018 IPR010035 ThiS, thiamine-biosynthesis MC49_RS06465 97a6d20b6debecf3cabc274de83d00c7 66 Pfam PF02597 ThiS family 4 66 5.8E-14 T 29-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 MC49_RS06465 97a6d20b6debecf3cabc274de83d00c7 66 Gene3D G3DSA:3.10.20.30 1 66 1.3E-20 T 29-03-2018 IPR012675 Beta-grasp domain MC49_RS06465 97a6d20b6debecf3cabc274de83d00c7 66 SUPERFAMILY SSF54285 1 66 2.04E-17 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp MC49_RS05260 a426966ada5bd8d0094b63dc40c3abab 513 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 15 113 5.7E-10 T 29-03-2018 IPR000014 PAS domain MC49_RS05260 a426966ada5bd8d0094b63dc40c3abab 513 SUPERFAMILY SSF55785 20 114 5.23E-23 T 29-03-2018 IPR000014 PAS domain MC49_RS05260 a426966ada5bd8d0094b63dc40c3abab 513 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 390 419 5.5E-38 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS05260 a426966ada5bd8d0094b63dc40c3abab 513 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 361 388 5.5E-38 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS05260 a426966ada5bd8d0094b63dc40c3abab 513 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 438 467 5.5E-38 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS05260 a426966ada5bd8d0094b63dc40c3abab 513 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 284 313 5.5E-38 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS05260 a426966ada5bd8d0094b63dc40c3abab 513 Pfam PF08447 PAS fold 31 106 3.5E-11 T 29-03-2018 IPR013655 PAS fold-3 GO:0005515 MC49_RS05260 a426966ada5bd8d0094b63dc40c3abab 513 Gene3D G3DSA:3.40.50.10600 6 129 9.8E-26 T 29-03-2018 MC49_RS05260 a426966ada5bd8d0094b63dc40c3abab 513 Gene3D G3DSA:1.10.287.950 320 512 9.6E-36 T 29-03-2018 MC49_RS05260 a426966ada5bd8d0094b63dc40c3abab 513 Gene3D G3DSA:1.10.287.950 208 319 6.4E-7 T 29-03-2018 MC49_RS05260 a426966ada5bd8d0094b63dc40c3abab 513 SMART SM00283 263 510 2.8E-63 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MC49_RS05260 a426966ada5bd8d0094b63dc40c3abab 513 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 323 476 4.0E-43 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MC49_RS05260 a426966ada5bd8d0094b63dc40c3abab 513 SUPERFAMILY SSF58104 235 510 8.76E-58 T 29-03-2018 MC49_RS00240 a8f9c0687485e99ba0891b38a66218c6 283 Pfam PF04383 KilA-N domain 9 133 2.6E-19 T 29-03-2018 IPR018004 KilA, N-terminal/APSES-type HTH, DNA-binding MC49_RS00240 a8f9c0687485e99ba0891b38a66218c6 283 Pfam PF10546 P63C domain 147 226 1.8E-10 T 29-03-2018 IPR018874 Bacteriophage Mx8, p63, C-terminal MC49_RS00240 a8f9c0687485e99ba0891b38a66218c6 283 SMART SM01252 10 134 5.3E-22 T 29-03-2018 IPR018004 KilA, N-terminal/APSES-type HTH, DNA-binding MC49_RS00240 a8f9c0687485e99ba0891b38a66218c6 283 Gene3D G3DSA:3.10.260.10 12 123 0.0013 T 29-03-2018 IPR003163 Transcription regulator HTH, APSES-type DNA-binding domain GO:0003677 MC49_RS00240 a8f9c0687485e99ba0891b38a66218c6 283 SUPERFAMILY SSF54616 74 136 2.35E-9 T 29-03-2018 IPR003163 Transcription regulator HTH, APSES-type DNA-binding domain GO:0003677 MC49_RS00240 a8f9c0687485e99ba0891b38a66218c6 283 SUPERFAMILY SSF54616 14 32 2.35E-9 T 29-03-2018 IPR003163 Transcription regulator HTH, APSES-type DNA-binding domain GO:0003677 MC49_RS08685 e799195695cea948663e682ff4ce2795 956 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 187 297 8.8E-29 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead MC49_RS08685 e799195695cea948663e682ff4ce2795 956 SUPERFAMILY SSF54665 165 317 2.49E-43 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead MC49_RS08685 e799195695cea948663e682ff4ce2795 956 Gene3D G3DSA:3.90.1170.50 180 299 2.8E-25 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead MC49_RS08685 e799195695cea948663e682ff4ce2795 956 Pfam PF01799 [2Fe-2S] binding domain 73 144 3.6E-10 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 MC49_RS08685 e799195695cea948663e682ff4ce2795 956 SMART SM01008 186 298 4.3E-37 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead MC49_RS08685 e799195695cea948663e682ff4ce2795 956 TIGRFAM TIGR03313 Se_sel_red_Mo: probable selenate reductase, molybdenum-binding subunit 5 955 0.0 T 29-03-2018 IPR017699 Molybdenum-binding protein YgfN/XdhD MC49_RS08685 e799195695cea948663e682ff4ce2795 956 Gene3D G3DSA:3.30.365.10 646 790 5.9E-33 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MC49_RS08685 e799195695cea948663e682ff4ce2795 956 Gene3D G3DSA:3.30.365.10 470 638 1.6E-36 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MC49_RS08685 e799195695cea948663e682ff4ce2795 956 PIRSF PIRSF000127 146 342 8.3E-15 T 29-03-2018 IPR016208 Aldehyde oxidase/xanthine dehydrogenase GO:0005506|GO:0016491|GO:0055114 MC49_RS08685 e799195695cea948663e682ff4ce2795 956 PIRSF PIRSF000127 356 944 5.8E-68 T 29-03-2018 IPR016208 Aldehyde oxidase/xanthine dehydrogenase GO:0005506|GO:0016491|GO:0055114 MC49_RS08685 e799195695cea948663e682ff4ce2795 956 PIRSF PIRSF000127 51 161 0.064 T 29-03-2018 IPR016208 Aldehyde oxidase/xanthine dehydrogenase GO:0005506|GO:0016491|GO:0055114 MC49_RS08685 e799195695cea948663e682ff4ce2795 956 Gene3D G3DSA:3.30.365.10 791 955 1.6E-45 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MC49_RS08685 e799195695cea948663e682ff4ce2795 956 SUPERFAMILY SSF56003 302 318 1.7E-163 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MC49_RS08685 e799195695cea948663e682ff4ce2795 956 SUPERFAMILY SSF56003 354 954 1.7E-163 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MC49_RS08685 e799195695cea948663e682ff4ce2795 956 Gene3D G3DSA:1.10.150.120 73 179 5.2E-15 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 MC49_RS08685 e799195695cea948663e682ff4ce2795 956 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 356 893 1.1E-147 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MC49_RS08685 e799195695cea948663e682ff4ce2795 956 Gene3D G3DSA:3.30.365.10 364 469 5.6E-33 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MC49_RS08685 e799195695cea948663e682ff4ce2795 956 SUPERFAMILY SSF47741 84 184 3.53E-15 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 MC49_RS16825 741bcc7f664a2b4fe8278bb1b9881fb6 271 PIRSF PIRSF002854 1 271 1.6E-90 T 29-03-2018 IPR004872 Lipoprotein NlpA family MC49_RS16825 741bcc7f664a2b4fe8278bb1b9881fb6 271 Pfam PF03180 NLPA lipoprotein 33 271 4.7E-88 T 29-03-2018 IPR004872 Lipoprotein NlpA family MC49_RS16825 741bcc7f664a2b4fe8278bb1b9881fb6 271 Gene3D G3DSA:3.40.190.10 129 271 2.7E-46 T 29-03-2018 MC49_RS16825 741bcc7f664a2b4fe8278bb1b9881fb6 271 SUPERFAMILY SSF53850 32 271 1.72E-74 T 29-03-2018 MC49_RS16825 741bcc7f664a2b4fe8278bb1b9881fb6 271 Gene3D G3DSA:3.40.190.10 32 128 1.9E-14 T 29-03-2018 MC49_RS16825 741bcc7f664a2b4fe8278bb1b9881fb6 271 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 17 271 4.1E-135 T 29-03-2018 IPR004872 Lipoprotein NlpA family MC49_RS19080 b12e240eb9b56b8aad70556aaca57fdb 269 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 36 50 5.1E-5 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MC49_RS19080 b12e240eb9b56b8aad70556aaca57fdb 269 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 50 68 5.1E-5 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MC49_RS19080 b12e240eb9b56b8aad70556aaca57fdb 269 SMART SM00420 18 70 1.0E-19 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MC49_RS19080 b12e240eb9b56b8aad70556aaca57fdb 269 SMART SM01134 87 248 2.1E-72 T 29-03-2018 MC49_RS19080 b12e240eb9b56b8aad70556aaca57fdb 269 ProSitePatterns PS00894 DeoR-type HTH domain signature. 18 52 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 MC49_RS19080 b12e240eb9b56b8aad70556aaca57fdb 269 SUPERFAMILY SSF100950 89 250 1.05E-32 T 29-03-2018 MC49_RS19080 b12e240eb9b56b8aad70556aaca57fdb 269 Gene3D G3DSA:3.40.50.1360 79 250 1.5E-42 T 29-03-2018 MC49_RS19080 b12e240eb9b56b8aad70556aaca57fdb 269 Pfam PF00455 DeoR C terminal sensor domain 89 246 3.1E-56 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain MC49_RS19080 b12e240eb9b56b8aad70556aaca57fdb 269 Gene3D G3DSA:1.10.10.10 3 73 2.4E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS19080 b12e240eb9b56b8aad70556aaca57fdb 269 SUPERFAMILY SSF46785 16 70 3.95E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS19080 b12e240eb9b56b8aad70556aaca57fdb 269 Pfam PF08220 DeoR-like helix-turn-helix domain 18 72 1.4E-19 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MC49_RS19030 1a0e51d89c122d6d1a33f129cfabd09e 499 Pfam PF00005 ABC transporter 27 177 3.7E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS19030 1a0e51d89c122d6d1a33f129cfabd09e 499 Pfam PF00005 ABC transporter 277 430 1.5E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS19030 1a0e51d89c122d6d1a33f129cfabd09e 499 Gene3D G3DSA:3.40.50.300 7 260 2.8E-52 T 29-03-2018 MC49_RS19030 1a0e51d89c122d6d1a33f129cfabd09e 499 ProSitePatterns PS00211 ABC transporters family signature. 403 417 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS19030 1a0e51d89c122d6d1a33f129cfabd09e 499 SUPERFAMILY SSF52540 275 487 8.32E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS19030 1a0e51d89c122d6d1a33f129cfabd09e 499 SUPERFAMILY SSF52540 11 237 1.78E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS19030 1a0e51d89c122d6d1a33f129cfabd09e 499 SMART SM00382 285 479 1.6E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS19030 1a0e51d89c122d6d1a33f129cfabd09e 499 SMART SM00382 36 231 2.4E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS19030 1a0e51d89c122d6d1a33f129cfabd09e 499 Gene3D G3DSA:3.40.50.300 261 495 1.1E-38 T 29-03-2018 MC49_RS05775 13fa1cc94a8e8c5764cb3ae3d914b91c 234 SUPERFAMILY SSF52172 2 190 7.83E-41 T 29-03-2018 IPR011006 CheY-like superfamily MC49_RS05775 13fa1cc94a8e8c5764cb3ae3d914b91c 234 Gene3D G3DSA:1.10.10.10 128 234 1.1E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS05775 13fa1cc94a8e8c5764cb3ae3d914b91c 234 Pfam PF00072 Response regulator receiver domain 4 112 4.7E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS05775 13fa1cc94a8e8c5764cb3ae3d914b91c 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 230 2.4E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MC49_RS05775 13fa1cc94a8e8c5764cb3ae3d914b91c 234 SMART SM00862 154 230 3.0E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MC49_RS05775 13fa1cc94a8e8c5764cb3ae3d914b91c 234 SMART SM00448 2 111 6.9E-45 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS05775 13fa1cc94a8e8c5764cb3ae3d914b91c 234 Gene3D G3DSA:3.40.50.2300 2 127 6.1E-39 T 29-03-2018 MC49_RS16620 f49e0dcd8d71f7b147ab372d0044da11 432 Gene3D G3DSA:3.90.190.20 296 432 6.1E-28 T 29-03-2018 MC49_RS16620 f49e0dcd8d71f7b147ab372d0044da11 432 Gene3D G3DSA:3.40.1190.10 2 295 7.2E-75 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MC49_RS16620 f49e0dcd8d71f7b147ab372d0044da11 432 SUPERFAMILY SSF53623 13 292 5.49E-82 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MC49_RS16620 f49e0dcd8d71f7b147ab372d0044da11 432 SUPERFAMILY SSF53244 294 424 1.83E-31 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MC49_RS16620 f49e0dcd8d71f7b147ab372d0044da11 432 Pfam PF08245 Mur ligase middle domain 55 206 1.2E-10 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MC49_RS16620 f49e0dcd8d71f7b147ab372d0044da11 432 PIRSF PIRSF001563 8 429 2.2E-106 T 29-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 MC49_RS16620 f49e0dcd8d71f7b147ab372d0044da11 432 TIGRFAM TIGR01499 folC: bifunctional protein FolC 40 423 9.6E-101 T 29-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 MC49_RS16620 f49e0dcd8d71f7b147ab372d0044da11 432 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 53 76 - T 29-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 MC49_RS16620 f49e0dcd8d71f7b147ab372d0044da11 432 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 145 160 - T 29-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 MC49_RS01275 a9024cb2b1c953d6ed523363649d4f4a 786 Gene3D G3DSA:1.10.3810.10 40 240 5.6E-46 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 MC49_RS01275 a9024cb2b1c953d6ed523363649d4f4a 786 Pfam PF00912 Transglycosylase 58 205 1.6E-41 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 MC49_RS01275 a9024cb2b1c953d6ed523363649d4f4a 786 SUPERFAMILY SSF56601 255 645 1.36E-95 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MC49_RS01275 a9024cb2b1c953d6ed523363649d4f4a 786 SUPERFAMILY SSF53955 38 246 7.31E-52 T 29-03-2018 IPR023346 Lysozyme-like domain MC49_RS01275 a9024cb2b1c953d6ed523363649d4f4a 786 Pfam PF06832 Penicillin-Binding Protein C-terminus Family 694 776 9.1E-13 T 29-03-2018 IPR009647 Penicillin-binding, C-terminal MC49_RS01275 a9024cb2b1c953d6ed523363649d4f4a 786 Pfam PF00905 Penicillin binding protein transpeptidase domain 311 525 1.9E-18 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MC49_RS01275 a9024cb2b1c953d6ed523363649d4f4a 786 Gene3D G3DSA:3.40.710.10 249 625 2.5E-73 T 29-03-2018 MC49_RS01275 a9024cb2b1c953d6ed523363649d4f4a 786 TIGRFAM TIGR02073 PBP_1c: penicillin-binding protein 1C 31 778 2.4E-256 T 29-03-2018 IPR011815 Penicillin-binding protein 1C GO:0008955|GO:0009252 MC49_RS13705 ccbbd906366b4bc567ebbd560400e90d 171 SUPERFAMILY SSF46767 83 164 2.22E-30 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MC49_RS13705 ccbbd906366b4bc567ebbd560400e90d 171 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 84 163 8.3E-34 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MC49_RS13705 ccbbd906366b4bc567ebbd560400e90d 171 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 85 164 3.3E-30 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MC49_RS13705 ccbbd906366b4bc567ebbd560400e90d 171 Gene3D G3DSA:1.10.10.10 80 166 1.0E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS13705 ccbbd906366b4bc567ebbd560400e90d 171 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 1 79 3.2E-8 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MC49_RS13705 ccbbd906366b4bc567ebbd560400e90d 171 Gene3D G3DSA:3.30.160.70 1 79 5.7E-16 T 29-03-2018 MC49_RS13705 ccbbd906366b4bc567ebbd560400e90d 171 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 5 164 35.174 T 29-03-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 MC49_RS13705 ccbbd906366b4bc567ebbd560400e90d 171 SUPERFAMILY SSF53155 4 89 1.86E-14 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MC49_RS17795 d3070e8ba9901244cc05ee3234d91406 231 Gene3D G3DSA:2.10.109.10 96 226 4.5E-20 T 29-03-2018 MC49_RS17795 d3070e8ba9901244cc05ee3234d91406 231 Gene3D G3DSA:1.10.260.40 1 72 9.7E-14 T 29-03-2018 MC49_RS17795 d3070e8ba9901244cc05ee3234d91406 231 Pfam PF00717 Peptidase S24-like 140 207 1.6E-11 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MC49_RS17795 d3070e8ba9901244cc05ee3234d91406 231 Pfam PF01381 Helix-turn-helix 15 67 2.5E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS17795 d3070e8ba9901244cc05ee3234d91406 231 SMART SM00530 12 67 4.6E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS17795 d3070e8ba9901244cc05ee3234d91406 231 SUPERFAMILY SSF51306 92 220 2.62E-20 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MC49_RS17795 d3070e8ba9901244cc05ee3234d91406 231 SUPERFAMILY SSF47413 9 71 3.26E-11 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS12170 032f66646686ddcbdf780f3a5c094725 147 Pfam PF00582 Universal stress protein family 1 147 3.2E-21 T 29-03-2018 IPR006016 UspA GO:0006950 MC49_RS12170 032f66646686ddcbdf780f3a5c094725 147 PRINTS PR01438 Universal stress protein signature 125 147 1.1E-9 T 29-03-2018 IPR006015 Universal stress protein A MC49_RS12170 032f66646686ddcbdf780f3a5c094725 147 PRINTS PR01438 Universal stress protein signature 108 120 1.1E-9 T 29-03-2018 IPR006015 Universal stress protein A MC49_RS12170 032f66646686ddcbdf780f3a5c094725 147 PRINTS PR01438 Universal stress protein signature 2 20 1.1E-9 T 29-03-2018 IPR006015 Universal stress protein A MC49_RS12170 032f66646686ddcbdf780f3a5c094725 147 Gene3D G3DSA:3.40.50.620 2 147 5.2E-24 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS12170 032f66646686ddcbdf780f3a5c094725 147 SUPERFAMILY SSF52402 5 147 1.17E-23 T 29-03-2018 MC49_RS12480 8e7f133686270d8f7d9a8bcf94ea2235 383 Pfam PF01312 FlhB HrpN YscU SpaS Family 8 347 2.0E-121 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MC49_RS12480 8e7f133686270d8f7d9a8bcf94ea2235 383 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 208 226 1.4E-38 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MC49_RS12480 8e7f133686270d8f7d9a8bcf94ea2235 383 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 10 32 1.4E-38 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MC49_RS12480 8e7f133686270d8f7d9a8bcf94ea2235 383 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 228 245 1.4E-38 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MC49_RS12480 8e7f133686270d8f7d9a8bcf94ea2235 383 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 272 287 1.4E-38 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MC49_RS12480 8e7f133686270d8f7d9a8bcf94ea2235 383 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 302 323 1.4E-38 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MC49_RS12480 8e7f133686270d8f7d9a8bcf94ea2235 383 SUPERFAMILY SSF160544 244 351 1.83E-39 T 29-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal MC49_RS12480 8e7f133686270d8f7d9a8bcf94ea2235 383 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 8 354 5.9E-127 T 29-03-2018 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 MC49_RS12480 8e7f133686270d8f7d9a8bcf94ea2235 383 Gene3D G3DSA:3.40.1690.10 218 353 3.5E-56 T 29-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal MC49_RS16300 36ad293c4317d4b07c8b6b2dfd6d2335 1046 SUPERFAMILY SSF82866 828 1025 6.02E-43 T 29-03-2018 MC49_RS16300 36ad293c4317d4b07c8b6b2dfd6d2335 1046 SUPERFAMILY SSF82714 720 802 4.05E-16 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MC49_RS16300 36ad293c4317d4b07c8b6b2dfd6d2335 1046 SUPERFAMILY SSF82714 193 276 3.4E-17 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MC49_RS16300 36ad293c4317d4b07c8b6b2dfd6d2335 1046 Hamap MF_01423 Multidrug resistance protein MdtB [mdtB]. 1 1038 34.291 T 29-03-2018 IPR022831 Multidrug resistance protein MdtB MC49_RS16300 36ad293c4317d4b07c8b6b2dfd6d2335 1046 SUPERFAMILY SSF82866 300 500 2.49E-46 T 29-03-2018 MC49_RS16300 36ad293c4317d4b07c8b6b2dfd6d2335 1046 SUPERFAMILY SSF82693 566 661 1.12E-14 T 29-03-2018 MC49_RS16300 36ad293c4317d4b07c8b6b2dfd6d2335 1046 Gene3D G3DSA:3.30.70.1430 50 152 2.2E-23 T 29-03-2018 MC49_RS16300 36ad293c4317d4b07c8b6b2dfd6d2335 1046 Pfam PF00873 AcrB/AcrD/AcrF family 14 1023 0.0 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS16300 36ad293c4317d4b07c8b6b2dfd6d2335 1046 PRINTS PR00702 Acriflavin resistance protein family signature 367 388 8.5E-82 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS16300 36ad293c4317d4b07c8b6b2dfd6d2335 1046 PRINTS PR00702 Acriflavin resistance protein family signature 448 471 8.5E-82 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS16300 36ad293c4317d4b07c8b6b2dfd6d2335 1046 PRINTS PR00702 Acriflavin resistance protein family signature 620 634 8.5E-82 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS16300 36ad293c4317d4b07c8b6b2dfd6d2335 1046 PRINTS PR00702 Acriflavin resistance protein family signature 48 66 8.5E-82 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS16300 36ad293c4317d4b07c8b6b2dfd6d2335 1046 PRINTS PR00702 Acriflavin resistance protein family signature 20 44 8.5E-82 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS16300 36ad293c4317d4b07c8b6b2dfd6d2335 1046 PRINTS PR00702 Acriflavin resistance protein family signature 473 496 8.5E-82 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS16300 36ad293c4317d4b07c8b6b2dfd6d2335 1046 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 8.5E-82 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS16300 36ad293c4317d4b07c8b6b2dfd6d2335 1046 PRINTS PR00702 Acriflavin resistance protein family signature 395 419 8.5E-82 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS16300 36ad293c4317d4b07c8b6b2dfd6d2335 1046 PRINTS PR00702 Acriflavin resistance protein family signature 340 363 8.5E-82 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS16300 36ad293c4317d4b07c8b6b2dfd6d2335 1046 Gene3D G3DSA:3.30.70.1430 568 667 1.1E-12 T 29-03-2018 MC49_RS16300 36ad293c4317d4b07c8b6b2dfd6d2335 1046 SUPERFAMILY SSF82693 803 852 3.4E-6 T 29-03-2018 MC49_RS16300 36ad293c4317d4b07c8b6b2dfd6d2335 1046 SUPERFAMILY SSF82693 676 716 3.4E-6 T 29-03-2018 MC49_RS16300 36ad293c4317d4b07c8b6b2dfd6d2335 1046 SUPERFAMILY SSF82693 50 143 7.06E-23 T 29-03-2018 MC49_RS16300 36ad293c4317d4b07c8b6b2dfd6d2335 1046 Gene3D G3DSA:1.20.1640.10 290 513 1.1E-46 T 29-03-2018 MC49_RS16300 36ad293c4317d4b07c8b6b2dfd6d2335 1046 SUPERFAMILY SSF82693 147 192 1.05E-21 T 29-03-2018 MC49_RS16300 36ad293c4317d4b07c8b6b2dfd6d2335 1046 SUPERFAMILY SSF82693 278 334 1.05E-21 T 29-03-2018 MC49_RS16300 36ad293c4317d4b07c8b6b2dfd6d2335 1046 Gene3D G3DSA:3.30.2090.10 191 279 3.1E-16 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MC49_RS16300 36ad293c4317d4b07c8b6b2dfd6d2335 1046 Gene3D G3DSA:3.30.2090.10 718 803 1.3E-17 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MC49_RS16300 36ad293c4317d4b07c8b6b2dfd6d2335 1046 Gene3D G3DSA:1.20.1640.10 822 1026 1.9E-34 T 29-03-2018 MC49_RS00875 5790678f28a377e6477ee7d6bc7c0d01 322 Pfam PF07549 SecD/SecF GG Motif 40 66 2.3E-12 T 29-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site MC49_RS00875 5790678f28a377e6477ee7d6bc7c0d01 322 Gene3D G3DSA:1.20.1640.10 69 310 3.3E-33 T 29-03-2018 MC49_RS00875 5790678f28a377e6477ee7d6bc7c0d01 322 PRINTS PR01755 Bacterial translocase SecF protein signature 207 225 3.2E-33 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MC49_RS00875 5790678f28a377e6477ee7d6bc7c0d01 322 PRINTS PR01755 Bacterial translocase SecF protein signature 159 173 3.2E-33 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MC49_RS00875 5790678f28a377e6477ee7d6bc7c0d01 322 PRINTS PR01755 Bacterial translocase SecF protein signature 239 254 3.2E-33 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MC49_RS00875 5790678f28a377e6477ee7d6bc7c0d01 322 PRINTS PR01755 Bacterial translocase SecF protein signature 44 59 3.2E-33 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MC49_RS00875 5790678f28a377e6477ee7d6bc7c0d01 322 Pfam PF02355 Protein export membrane protein 116 300 1.8E-72 T 29-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial MC49_RS00875 5790678f28a377e6477ee7d6bc7c0d01 322 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 128 288 2.3E-55 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MC49_RS00875 5790678f28a377e6477ee7d6bc7c0d01 322 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 17 302 28.793 T 29-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 MC49_RS00875 5790678f28a377e6477ee7d6bc7c0d01 322 SUPERFAMILY SSF82866 80 302 5.23E-42 T 29-03-2018 MC49_RS00875 5790678f28a377e6477ee7d6bc7c0d01 322 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 45 291 3.1E-89 T 29-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 MC49_RS16940 5246d5a3afa6b68990427e163dcada08 367 SUPERFAMILY SSF52402 5 295 8.38E-59 T 29-03-2018 MC49_RS16940 5246d5a3afa6b68990427e163dcada08 367 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 7 362 41.048 T 29-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 MC49_RS16940 5246d5a3afa6b68990427e163dcada08 367 Pfam PF03054 tRNA methyl transferase 7 361 8.6E-146 T 29-03-2018 MC49_RS16940 5246d5a3afa6b68990427e163dcada08 367 Gene3D G3DSA:2.30.30.280 214 281 2.4E-28 T 29-03-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 MC49_RS16940 5246d5a3afa6b68990427e163dcada08 367 Gene3D G3DSA:2.40.30.10 283 367 1.9E-28 T 29-03-2018 MC49_RS16940 5246d5a3afa6b68990427e163dcada08 367 Gene3D G3DSA:3.40.50.620 1 213 5.5E-67 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS16940 5246d5a3afa6b68990427e163dcada08 367 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 7 361 9.0E-158 T 29-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 MC49_RS00820 9f964f0d246af7c606e1243bcb76b8d5 206 Gene3D G3DSA:3.40.50.880 1 200 7.8E-40 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MC49_RS00820 9f964f0d246af7c606e1243bcb76b8d5 206 TIGRFAM TIGR01383 not_thiJ: DJ-1 family protein 5 183 6.7E-60 T 29-03-2018 IPR006287 Protein DJ-1 MC49_RS00820 9f964f0d246af7c606e1243bcb76b8d5 206 SUPERFAMILY SSF52317 2 189 1.15E-47 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MC49_RS00820 9f964f0d246af7c606e1243bcb76b8d5 206 Pfam PF01965 DJ-1/PfpI family 4 170 6.5E-41 T 29-03-2018 IPR002818 DJ-1/PfpI MC49_RS12030 f4b8c07abd7b5d40c5b28ab9135af590 735 Gene3D G3DSA:2.40.170.20 178 735 6.7E-35 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MC49_RS12030 f4b8c07abd7b5d40c5b28ab9135af590 735 Pfam PF07715 TonB-dependent Receptor Plug Domain 2 126 1.8E-11 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MC49_RS12030 f4b8c07abd7b5d40c5b28ab9135af590 735 Gene3D G3DSA:2.170.130.10 1 140 6.5E-13 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MC49_RS12030 f4b8c07abd7b5d40c5b28ab9135af590 735 SUPERFAMILY SSF56935 2 145 1.33E-53 T 29-03-2018 MC49_RS12030 f4b8c07abd7b5d40c5b28ab9135af590 735 SUPERFAMILY SSF56935 177 735 1.33E-53 T 29-03-2018 MC49_RS07635 421607949d9214fc6a14cdbdd50583ef 379 PRINTS PR00096 Glutamine amidotransferase superfamily signature 264 275 4.2E-11 T 29-03-2018 MC49_RS07635 421607949d9214fc6a14cdbdd50583ef 379 PRINTS PR00096 Glutamine amidotransferase superfamily signature 236 245 4.2E-11 T 29-03-2018 MC49_RS07635 421607949d9214fc6a14cdbdd50583ef 379 PRINTS PR00096 Glutamine amidotransferase superfamily signature 349 362 4.2E-11 T 29-03-2018 MC49_RS07635 421607949d9214fc6a14cdbdd50583ef 379 SUPERFAMILY SSF52021 3 143 1.01E-56 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MC49_RS07635 421607949d9214fc6a14cdbdd50583ef 379 Gene3D G3DSA:3.50.30.20 2 151 3.4E-62 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MC49_RS07635 421607949d9214fc6a14cdbdd50583ef 379 PRINTS PR00097 Anthranilate synthase component II signature 264 275 1.4E-5 T 29-03-2018 MC49_RS07635 421607949d9214fc6a14cdbdd50583ef 379 PRINTS PR00097 Anthranilate synthase component II signature 349 362 1.4E-5 T 29-03-2018 MC49_RS07635 421607949d9214fc6a14cdbdd50583ef 379 PRINTS PR00097 Anthranilate synthase component II signature 236 245 1.4E-5 T 29-03-2018 MC49_RS07635 421607949d9214fc6a14cdbdd50583ef 379 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 5 375 2.2E-150 T 29-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MC49_RS07635 421607949d9214fc6a14cdbdd50583ef 379 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 5 132 4.0E-52 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MC49_RS07635 421607949d9214fc6a14cdbdd50583ef 379 Gene3D G3DSA:3.40.50.880 152 379 2.4E-67 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MC49_RS07635 421607949d9214fc6a14cdbdd50583ef 379 Pfam PF00117 Glutamine amidotransferase class-I 197 372 5.0E-50 T 29-03-2018 IPR017926 Glutamine amidotransferase MC49_RS07635 421607949d9214fc6a14cdbdd50583ef 379 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 3 378 48.4 T 29-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MC49_RS07635 421607949d9214fc6a14cdbdd50583ef 379 SUPERFAMILY SSF52317 153 377 2.37E-63 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MC49_RS07635 421607949d9214fc6a14cdbdd50583ef 379 SMART SM01097 3 133 2.8E-89 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MC49_RS07635 421607949d9214fc6a14cdbdd50583ef 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 264 280 3.1E-40 T 29-03-2018 MC49_RS07635 421607949d9214fc6a14cdbdd50583ef 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 233 247 3.1E-40 T 29-03-2018 MC49_RS07635 421607949d9214fc6a14cdbdd50583ef 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 281 298 3.1E-40 T 29-03-2018 MC49_RS07635 421607949d9214fc6a14cdbdd50583ef 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 306 317 3.1E-40 T 29-03-2018 MC49_RS07635 421607949d9214fc6a14cdbdd50583ef 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 194 208 3.1E-40 T 29-03-2018 MC49_RS15650 9ce26a859fd94f930022dcdbc8013beb 288 SUPERFAMILY SSF53613 1 283 1.64E-73 T 29-03-2018 IPR029056 Ribokinase-like MC49_RS15650 9ce26a859fd94f930022dcdbc8013beb 288 Gene3D G3DSA:3.40.1190.20 1 287 5.5E-61 T 29-03-2018 IPR029056 Ribokinase-like MC49_RS15650 9ce26a859fd94f930022dcdbc8013beb 288 TIGRFAM TIGR00687 pyridox_kin: pyridoxal kinase 1 287 6.8E-128 T 29-03-2018 IPR004625 Pyridoxine kinase GO:0008478|GO:0009443 KEGG: 00750+2.7.1.35|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-6798695|Reactome: R-HSA-964975 MC49_RS15650 9ce26a859fd94f930022dcdbc8013beb 288 Pfam PF08543 Phosphomethylpyrimidine kinase 68 260 1.7E-15 T 29-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 MC49_RS15650 9ce26a859fd94f930022dcdbc8013beb 288 Hamap MF_01639 Pyridoxal kinase PdxY [pdxY]. 1 287 53.649 T 29-03-2018 IPR023685 Pyridoxal kinase PdxY GO:0008478|GO:0009443 KEGG: 00750+2.7.1.35|MetaCyc: PWY-7204|MetaCyc: PWY-7282 MC49_RS08780 4aee9ad0fe93885e0acf9b064f46f5cf 400 SUPERFAMILY SSF53686 39 352 3.93E-61 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MC49_RS08780 4aee9ad0fe93885e0acf9b064f46f5cf 400 Gene3D G3DSA:3.40.50.1100 52 180 6.3E-31 T 29-03-2018 MC49_RS08780 4aee9ad0fe93885e0acf9b064f46f5cf 400 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 41 375 1.3E-51 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MC49_RS08780 4aee9ad0fe93885e0acf9b064f46f5cf 400 TIGRFAM TIGR03528 2_3_DAP_am_ly: diaminopropionate ammonia-lyase 6 393 2.0E-186 T 29-03-2018 IPR019871 Diaminopropionate ammonia-lyase, subgroup GO:0008838 MC49_RS08780 4aee9ad0fe93885e0acf9b064f46f5cf 400 TIGRFAM TIGR01747 diampropi_NH3ly: diaminopropionate ammonia-lyase family 23 392 5.8E-186 T 29-03-2018 IPR010081 Diaminopropionate ammonia-lyase GO:0008838|GO:0030170 MC49_RS08780 4aee9ad0fe93885e0acf9b064f46f5cf 400 Gene3D G3DSA:3.40.50.1100 181 400 1.9E-25 T 29-03-2018 MC49_RS09930 0b1da8225f81ddbae9384ccab810abe6 325 SUPERFAMILY SSF55120 78 321 5.14E-78 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS09930 0b1da8225f81ddbae9384ccab810abe6 325 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 14 312 3.5E-106 T 29-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS09930 0b1da8225f81ddbae9384ccab810abe6 325 SMART SM00363 18 83 7.0E-10 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MC49_RS09930 0b1da8225f81ddbae9384ccab810abe6 325 Pfam PF00849 RNA pseudouridylate synthase 92 242 1.6E-31 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS09930 0b1da8225f81ddbae9384ccab810abe6 325 SUPERFAMILY SSF55174 17 69 9.76E-11 T 29-03-2018 MC49_RS09930 0b1da8225f81ddbae9384ccab810abe6 325 Gene3D G3DSA:3.10.290.10 2 76 4.7E-20 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MC49_RS09930 0b1da8225f81ddbae9384ccab810abe6 325 Gene3D G3DSA:3.30.2350.10 83 316 3.7E-68 T 29-03-2018 MC49_RS09930 0b1da8225f81ddbae9384ccab810abe6 325 Pfam PF01479 S4 domain 18 65 4.1E-10 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MC49_RS09930 0b1da8225f81ddbae9384ccab810abe6 325 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 135 149 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS07930 b4e8b83452690c09c8b353dbf38606e2 365 Pfam PF03562 MltA specific insert domain 61 256 1.1E-41 T 29-03-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 MC49_RS07930 b4e8b83452690c09c8b353dbf38606e2 365 Gene3D G3DSA:2.40.240.50 58 258 1.3E-60 T 29-03-2018 MC49_RS07930 b4e8b83452690c09c8b353dbf38606e2 365 SMART SM00925 124 257 7.3E-68 T 29-03-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 MC49_RS07930 b4e8b83452690c09c8b353dbf38606e2 365 Pfam PF06725 3D domain 277 354 2.1E-23 T 29-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 MC49_RS07930 b4e8b83452690c09c8b353dbf38606e2 365 SUPERFAMILY SSF50685 24 353 2.27E-109 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain MC49_RS07930 b4e8b83452690c09c8b353dbf38606e2 365 PIRSF PIRSF019422 2 148 1.9E-16 T 29-03-2018 IPR026044 Membrane-bound lytic murein transglycosylase A MC49_RS07930 b4e8b83452690c09c8b353dbf38606e2 365 PIRSF PIRSF019422 145 358 2.6E-68 T 29-03-2018 IPR026044 Membrane-bound lytic murein transglycosylase A MC49_RS14235 d579b18b74fb33b70f1c29b8688ac5ae 97 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 1 83 1.2E-32 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 MC49_RS14235 d579b18b74fb33b70f1c29b8688ac5ae 97 SUPERFAMILY SSF55229 32 84 7.72E-17 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 MC49_RS14235 d579b18b74fb33b70f1c29b8688ac5ae 97 Gene3D G3DSA:3.30.1070.10 1 83 9.4E-27 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 MC49_RS14235 d579b18b74fb33b70f1c29b8688ac5ae 97 Hamap MF_00262 Cell division topological specificity factor [minE]. 3 86 18.649 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 MC49_RS14235 d579b18b74fb33b70f1c29b8688ac5ae 97 Pfam PF03776 Septum formation topological specificity factor MinE 14 82 1.8E-23 T 29-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 MC49_RS03350 6bedc7aee598a303e0b2c51685f5fc1b 295 Pfam PF13181 Tetratricopeptide repeat 63 95 0.2 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MC49_RS03350 6bedc7aee598a303e0b2c51685f5fc1b 295 PIRSF PIRSF004654 1 293 1.8E-108 T 29-03-2018 IPR023605 Lipoprotein NlpI MC49_RS03350 6bedc7aee598a303e0b2c51685f5fc1b 295 Pfam PF13432 Tetratricopeptide repeat 104 165 7.3E-6 T 29-03-2018 MC49_RS03350 6bedc7aee598a303e0b2c51685f5fc1b 295 SUPERFAMILY SSF48452 28 283 1.29E-71 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MC49_RS03350 6bedc7aee598a303e0b2c51685f5fc1b 295 SMART SM00028 235 268 6.3 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MC49_RS03350 6bedc7aee598a303e0b2c51685f5fc1b 295 SMART SM00028 97 130 1.2E-4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MC49_RS03350 6bedc7aee598a303e0b2c51685f5fc1b 295 SMART SM00028 63 96 4.1 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MC49_RS03350 6bedc7aee598a303e0b2c51685f5fc1b 295 Gene3D G3DSA:1.25.40.10 21 295 1.6E-47 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MC49_RS05350 ba8778446474a488f4200ac88e7db969 119 Gene3D G3DSA:3.30.230.10 1 119 6.5E-32 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MC49_RS05350 ba8778446474a488f4200ac88e7db969 119 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 6 115 18.177 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 MC49_RS05350 ba8778446474a488f4200ac88e7db969 119 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 56 70 - T 29-03-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 MC49_RS05350 ba8778446474a488f4200ac88e7db969 119 Pfam PF00825 Ribonuclease P 6 111 3.0E-32 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 MC49_RS05350 ba8778446474a488f4200ac88e7db969 119 SUPERFAMILY SSF54211 5 115 3.54E-31 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MC49_RS05350 ba8778446474a488f4200ac88e7db969 119 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 16 101 2.0E-37 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 MC49_RS05350 ba8778446474a488f4200ac88e7db969 119 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 5 115 8.7E-35 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 MC49_RS01835 aada16619177b5ae7ca85207845251e3 373 Pfam PF05651 Putative sugar diacid recognition 6 139 9.7E-52 T 29-03-2018 IPR008599 Putative sugar diacid recognition MC49_RS01835 aada16619177b5ae7ca85207845251e3 373 Pfam PF13556 PucR C-terminal helix-turn-helix domain 313 369 1.2E-18 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain MC49_RS01835 aada16619177b5ae7ca85207845251e3 373 Gene3D G3DSA:1.10.10.60 295 349 4.3E-6 T 29-03-2018 MC49_RS06070 54c6b452fcaa25d5fed34c550020799f 207 SMART SM00072 3 187 7.9E-83 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit MC49_RS06070 54c6b452fcaa25d5fed34c550020799f 207 ProSitePatterns PS00856 Guanylate kinase-like signature. 40 57 - T 29-03-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 MC49_RS06070 54c6b452fcaa25d5fed34c550020799f 207 SUPERFAMILY SSF52540 3 189 1.03E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS06070 54c6b452fcaa25d5fed34c550020799f 207 Gene3D G3DSA:3.30.63.10 52 81 8.7E-25 T 29-03-2018 MC49_RS06070 54c6b452fcaa25d5fed34c550020799f 207 Gene3D G3DSA:3.40.50.300 82 188 4.6E-34 T 29-03-2018 MC49_RS06070 54c6b452fcaa25d5fed34c550020799f 207 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 4 184 1.6E-73 T 29-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 MC49_RS06070 54c6b452fcaa25d5fed34c550020799f 207 Gene3D G3DSA:3.40.50.300 1 51 2.9E-4 T 29-03-2018 MC49_RS06070 54c6b452fcaa25d5fed34c550020799f 207 Pfam PF00625 Guanylate kinase 5 186 3.1E-64 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit MC49_RS06070 54c6b452fcaa25d5fed34c550020799f 207 Hamap MF_00328 Guanylate kinase [gmk]. 2 187 37.56 T 29-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 MC49_RS14010 86888a7b2754e619aa0e2009ccc0c5f6 184 Pfam PF06185 YecM protein 12 183 8.1E-67 T 29-03-2018 IPR010393 Protein of unknown function DUF991 MC49_RS14010 86888a7b2754e619aa0e2009ccc0c5f6 184 SUPERFAMILY SSF54593 9 183 4.39E-63 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MC49_RS14010 86888a7b2754e619aa0e2009ccc0c5f6 184 Gene3D G3DSA:3.10.180.10 7 184 8.4E-68 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MC49_RS02080 2c600e7d5e31f98f20e5d0cfd46d48f8 188 SMART SM00841 131 186 1.9E-33 T 29-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 MC49_RS02080 2c600e7d5e31f98f20e5d0cfd46d48f8 188 SUPERFAMILY SSF50104 2 63 3.21E-20 T 29-03-2018 IPR008991 Translation protein SH3-like domain MC49_RS02080 2c600e7d5e31f98f20e5d0cfd46d48f8 188 SMART SM01185 69 123 3.1E-25 T 29-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 MC49_RS02080 2c600e7d5e31f98f20e5d0cfd46d48f8 188 SUPERFAMILY SSF50249 70 128 1.11E-17 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS02080 2c600e7d5e31f98f20e5d0cfd46d48f8 188 Gene3D G3DSA:2.40.50.140 67 129 2.1E-24 T 29-03-2018 MC49_RS02080 2c600e7d5e31f98f20e5d0cfd46d48f8 188 ProSitePatterns PS01275 Elongation factor P signature. 152 171 - T 29-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site MC49_RS02080 2c600e7d5e31f98f20e5d0cfd46d48f8 188 PIRSF PIRSF005901 2 188 2.1E-66 T 29-03-2018 IPR020599 Translation elongation factor P/YeiP MC49_RS02080 2c600e7d5e31f98f20e5d0cfd46d48f8 188 Pfam PF09285 Elongation factor P, C-terminal 131 186 3.3E-26 T 29-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 MC49_RS02080 2c600e7d5e31f98f20e5d0cfd46d48f8 188 Gene3D G3DSA:2.40.50.140 131 186 8.9E-28 T 29-03-2018 MC49_RS02080 2c600e7d5e31f98f20e5d0cfd46d48f8 188 SUPERFAMILY SSF50249 130 187 7.71E-19 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS02080 2c600e7d5e31f98f20e5d0cfd46d48f8 188 TIGRFAM TIGR00038 efp: translation elongation factor P 4 187 6.8E-77 T 29-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 MC49_RS02080 2c600e7d5e31f98f20e5d0cfd46d48f8 188 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 5 61 1.3E-23 T 29-03-2018 IPR013185 Translation elongation factor, KOW-like MC49_RS02080 2c600e7d5e31f98f20e5d0cfd46d48f8 188 Pfam PF01132 Elongation factor P (EF-P) OB domain 72 123 5.7E-22 T 29-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 MC49_RS02080 2c600e7d5e31f98f20e5d0cfd46d48f8 188 Hamap MF_00141 Elongation factor P [efp]. 3 187 49.914 T 29-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 MC49_RS02080 2c600e7d5e31f98f20e5d0cfd46d48f8 188 Gene3D G3DSA:2.30.30.30 4 63 7.3E-24 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 MC49_RS16615 2e73b775907a04979c199202289c8c60 230 SUPERFAMILY SSF110997 155 226 1.83E-13 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 MC49_RS16615 2e73b775907a04979c199202289c8c60 230 Gene3D G3DSA:3.30.70.1070 158 228 5.1E-10 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 MC49_RS16615 2e73b775907a04979c199202289c8c60 230 Hamap MF_02022 Cell division protein DedD [dedD]. 10 230 24.523 T 29-03-2018 IPR032898 Cell division protein DedD GO:0030428|GO:0032506 MC49_RS16615 2e73b775907a04979c199202289c8c60 230 Pfam PF05036 Sporulation related domain 157 222 1.5E-8 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 MC49_RS15980 8e70bc2371e1ba6ac8c648acf910d5df 179 Gene3D G3DSA:3.30.110.10 87 179 4.9E-35 T 29-03-2018 MC49_RS15980 8e70bc2371e1ba6ac8c648acf910d5df 179 SUPERFAMILY SSF55200 90 179 1.03E-34 T 29-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 MC49_RS15980 8e70bc2371e1ba6ac8c648acf910d5df 179 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 15 84 1.1E-30 T 29-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MC49_RS15980 8e70bc2371e1ba6ac8c648acf910d5df 179 Gene3D G3DSA:3.10.20.80 10 86 5.0E-32 T 29-03-2018 MC49_RS15980 8e70bc2371e1ba6ac8c648acf910d5df 179 SUPERFAMILY SSF54364 13 86 3.01E-29 T 29-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MC49_RS15980 8e70bc2371e1ba6ac8c648acf910d5df 179 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 9 179 30.893 T 29-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MC49_RS15980 8e70bc2371e1ba6ac8c648acf910d5df 179 ProSitePatterns PS00938 Initiation factor 3 signature. 66 79 - T 29-03-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 MC49_RS15980 8e70bc2371e1ba6ac8c648acf910d5df 179 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 91 177 7.2E-38 T 29-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 MC49_RS15980 8e70bc2371e1ba6ac8c648acf910d5df 179 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 15 179 3.3E-76 T 29-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MC49_RS18790 bf3e4848d8468e880a565a76b1f2e4c0 164 Gene3D G3DSA:3.90.960.10 1 157 2.1E-33 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MC49_RS18790 bf3e4848d8468e880a565a76b1f2e4c0 164 Pfam PF04073 Aminoacyl-tRNA editing domain 29 144 1.6E-22 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MC49_RS18790 bf3e4848d8468e880a565a76b1f2e4c0 164 SUPERFAMILY SSF55826 2 152 2.22E-32 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MC49_RS14710 6e5d4d2d9fe373a2821814a8f0bb0d41 719 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 66 719 1.3E-85 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 MC49_RS14710 6e5d4d2d9fe373a2821814a8f0bb0d41 719 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 702 719 - T 29-03-2018 IPR010917 TonB-dependent receptor, conserved site MC49_RS14710 6e5d4d2d9fe373a2821814a8f0bb0d41 719 Pfam PF07715 TonB-dependent Receptor Plug Domain 66 162 1.8E-8 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MC49_RS14710 6e5d4d2d9fe373a2821814a8f0bb0d41 719 Gene3D G3DSA:2.170.130.10 21 175 2.5E-14 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MC49_RS14710 6e5d4d2d9fe373a2821814a8f0bb0d41 719 Gene3D G3DSA:2.40.170.20 176 719 1.9E-63 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MC49_RS14710 6e5d4d2d9fe373a2821814a8f0bb0d41 719 SUPERFAMILY SSF56935 18 719 1.58E-96 T 29-03-2018 MC49_RS00830 e3f1480340b713ec8d18e289c8abc2e4 482 TIGRFAM TIGR04271 ThiI_C_thiazole: thiazole biosynthesis domain 382 482 1.5E-41 T 29-03-2018 IPR026340 Thiazole biosynthesis domain GO:0052837 MC49_RS00830 e3f1480340b713ec8d18e289c8abc2e4 482 SMART SM00981 75 165 5.6E-25 T 29-03-2018 IPR004114 THUMP domain GO:0003723 MC49_RS00830 e3f1480340b713ec8d18e289c8abc2e4 482 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 482 227.54 T 29-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 MC49_RS00830 e3f1480340b713ec8d18e289c8abc2e4 482 Gene3D G3DSA:3.40.250.10 392 482 1.1E-11 T 29-03-2018 IPR001763 Rhodanese-like domain MC49_RS00830 e3f1480340b713ec8d18e289c8abc2e4 482 SUPERFAMILY SSF52821 397 481 6.72E-11 T 29-03-2018 IPR001763 Rhodanese-like domain MC49_RS00830 e3f1480340b713ec8d18e289c8abc2e4 482 SUPERFAMILY SSF52402 174 372 3.97E-42 T 29-03-2018 MC49_RS00830 e3f1480340b713ec8d18e289c8abc2e4 482 Pfam PF02926 THUMP domain 47 165 1.1E-23 T 29-03-2018 IPR004114 THUMP domain GO:0003723 MC49_RS00830 e3f1480340b713ec8d18e289c8abc2e4 482 Gene3D G3DSA:3.40.50.620 175 391 8.8E-27 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS00830 e3f1480340b713ec8d18e289c8abc2e4 482 SUPERFAMILY SSF143437 1 173 4.19E-50 T 29-03-2018 MC49_RS00830 e3f1480340b713ec8d18e289c8abc2e4 482 Gene3D G3DSA:3.30.70.1510 2 81 7.2E-22 T 29-03-2018 MC49_RS00830 e3f1480340b713ec8d18e289c8abc2e4 482 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 175 369 1.9E-79 T 29-03-2018 IPR020536 Thil, AANH domain GO:0004810 MC49_RS00830 e3f1480340b713ec8d18e289c8abc2e4 482 Gene3D G3DSA:3.30.2300.10 82 163 3.0E-22 T 29-03-2018 MC49_RS00830 e3f1480340b713ec8d18e289c8abc2e4 482 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 4 376 8.5E-131 T 29-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 MC49_RS15105 0369f8649b4326891bc668748e3484ed 324 Gene3D G3DSA:3.40.190.10 91 180 1.1E-21 T 29-03-2018 MC49_RS15105 0369f8649b4326891bc668748e3484ed 324 Pfam PF03466 LysR substrate binding domain 91 288 6.9E-42 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS15105 0369f8649b4326891bc668748e3484ed 324 SUPERFAMILY SSF53850 90 321 1.22E-42 T 29-03-2018 MC49_RS15105 0369f8649b4326891bc668748e3484ed 324 SUPERFAMILY SSF46785 1 113 2.94E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS15105 0369f8649b4326891bc668748e3484ed 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.9E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS15105 0369f8649b4326891bc668748e3484ed 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.9E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS15105 0369f8649b4326891bc668748e3484ed 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.9E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS15105 0369f8649b4326891bc668748e3484ed 324 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 64 7.7E-15 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS15105 0369f8649b4326891bc668748e3484ed 324 Gene3D G3DSA:3.40.190.10 181 267 3.7E-22 T 29-03-2018 MC49_RS15105 0369f8649b4326891bc668748e3484ed 324 Gene3D G3DSA:1.10.10.10 1 90 3.8E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS11740 07c1eed07d704be1fd3b89a139bb4775 128 Hamap MF_00925 Outer membrane protein assembly factor BamE [bamE]. 4 112 32.317 T 29-03-2018 IPR026592 Outer membrane protein assembly factor BamE MC49_RS11740 07c1eed07d704be1fd3b89a139bb4775 128 Pfam PF04355 SmpA / OmlA family 35 104 1.1E-26 T 29-03-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 MC49_RS11740 07c1eed07d704be1fd3b89a139bb4775 128 Gene3D G3DSA:3.30.1450.10 35 112 1.3E-8 T 29-03-2018 MC49_RS09980 5755ed8eb317907572138b1f8362a2a0 452 Gene3D G3DSA:3.30.870.10 247 419 1.6E-18 T 29-03-2018 MC49_RS09980 5755ed8eb317907572138b1f8362a2a0 452 Pfam PF13091 PLD-like domain 258 406 3.1E-21 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 MC49_RS09980 5755ed8eb317907572138b1f8362a2a0 452 Gene3D G3DSA:3.30.870.10 14 215 4.4E-16 T 29-03-2018 MC49_RS09980 5755ed8eb317907572138b1f8362a2a0 452 PIRSF PIRSF000850 1 452 8.6E-226 T 29-03-2018 MC49_RS09980 5755ed8eb317907572138b1f8362a2a0 452 SUPERFAMILY SSF56024 253 397 8.48E-20 T 29-03-2018 MC49_RS09980 5755ed8eb317907572138b1f8362a2a0 452 SUPERFAMILY SSF56024 10 191 1.63E-24 T 29-03-2018 MC49_RS09980 5755ed8eb317907572138b1f8362a2a0 452 SMART SM00155 133 159 0.028 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MC49_RS09980 5755ed8eb317907572138b1f8362a2a0 452 SMART SM00155 353 380 0.0021 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MC49_RS16710 97d505639e08af758f7cfe9bb2b438d5 362 TIGRFAM TIGR00033 aroC: chorismate synthase 10 349 3.0E-139 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MC49_RS16710 97d505639e08af758f7cfe9bb2b438d5 362 ProSitePatterns PS00788 Chorismate synthase signature 2. 124 140 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MC49_RS16710 97d505639e08af758f7cfe9bb2b438d5 362 SUPERFAMILY SSF103263 4 352 7.33E-149 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MC49_RS16710 97d505639e08af758f7cfe9bb2b438d5 362 Hamap MF_00300 Chorismate synthase [aroC]. 10 352 37.712 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MC49_RS16710 97d505639e08af758f7cfe9bb2b438d5 362 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MC49_RS16710 97d505639e08af758f7cfe9bb2b438d5 362 Pfam PF01264 Chorismate synthase 10 345 1.6E-142 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MC49_RS16710 97d505639e08af758f7cfe9bb2b438d5 362 Gene3D G3DSA:3.60.150.10 3 356 6.6E-160 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MC49_RS16710 97d505639e08af758f7cfe9bb2b438d5 362 PIRSF PIRSF001456 3 356 3.5E-141 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MC49_RS16710 97d505639e08af758f7cfe9bb2b438d5 362 ProSitePatterns PS00789 Chorismate synthase signature 3. 319 335 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MC49_RS18595 9bbbc1d9f35b47106120cf1bb86586f2 68 Hamap MF_00649 DNA gyrase inhibitor YacG [yacG]. 3 59 18.592 T 29-03-2018 IPR005584 DNA gyrase inhibitor YacG GO:0008270 MC49_RS18595 9bbbc1d9f35b47106120cf1bb86586f2 68 Gene3D G3DSA:3.30.50.10 2 60 1.5E-26 T 29-03-2018 IPR013088 Zinc finger, NHR/GATA-type GO:0006355|GO:0008270 MC49_RS18595 9bbbc1d9f35b47106120cf1bb86586f2 68 SUPERFAMILY SSF57716 3 62 3.92E-22 T 29-03-2018 MC49_RS18595 9bbbc1d9f35b47106120cf1bb86586f2 68 Pfam PF03884 DNA gyrase inhibitor YacG 7 57 2.2E-25 T 29-03-2018 IPR005584 DNA gyrase inhibitor YacG GO:0008270 MC49_RS08105 c78bf33cd5bb915450ec6d50f6a7b75e 1159 Pfam PF01336 OB-fold nucleic acid binding domain 994 1069 1.8E-6 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 MC49_RS08105 c78bf33cd5bb915450ec6d50f6a7b75e 1159 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 6 1030 0.0 T 29-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS08105 c78bf33cd5bb915450ec6d50f6a7b75e 1159 Pfam PF14579 Helix-hairpin-helix motif 808 896 6.5E-25 T 29-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS08105 c78bf33cd5bb915450ec6d50f6a7b75e 1159 SUPERFAMILY SSF89550 6 263 4.9E-12 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 MC49_RS08105 c78bf33cd5bb915450ec6d50f6a7b75e 1159 Pfam PF02811 PHP domain 8 171 4.9E-40 T 29-03-2018 IPR004013 PHP domain GO:0003824 MC49_RS08105 c78bf33cd5bb915450ec6d50f6a7b75e 1159 Gene3D G3DSA:1.10.150.280 782 893 4.9E-9 T 29-03-2018 MC49_RS08105 c78bf33cd5bb915450ec6d50f6a7b75e 1159 SMART SM00481 7 74 7.5E-20 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal MC49_RS08105 c78bf33cd5bb915450ec6d50f6a7b75e 1159 Gene3D G3DSA:2.40.50.140 973 1073 3.2E-14 T 29-03-2018 MC49_RS08105 c78bf33cd5bb915450ec6d50f6a7b75e 1159 Gene3D G3DSA:3.20.20.140 1 230 8.1E-35 T 29-03-2018 MC49_RS08105 c78bf33cd5bb915450ec6d50f6a7b75e 1159 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 291 735 1.2E-176 T 29-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS08105 c78bf33cd5bb915450ec6d50f6a7b75e 1159 SUPERFAMILY SSF50249 974 1071 4.23E-5 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS11100 43eb334fe98e7cd4060e2815b28528bc 760 Gene3D G3DSA:3.20.70.20 2 760 7.5E-291 T 29-03-2018 MC49_RS11100 43eb334fe98e7cd4060e2815b28528bc 760 Pfam PF02901 Pyruvate formate lyase-like 23 614 3.6E-203 T 29-03-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 MC49_RS11100 43eb334fe98e7cd4060e2815b28528bc 760 ProSitePatterns PS00850 Glycine radical domain signature. 730 738 - T 29-03-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site MC49_RS11100 43eb334fe98e7cd4060e2815b28528bc 760 PIRSF PIRSF000379 8 760 0.0 T 29-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 MC49_RS11100 43eb334fe98e7cd4060e2815b28528bc 760 Pfam PF01228 Glycine radical 630 741 1.6E-42 T 29-03-2018 IPR001150 Glycine radical domain GO:0003824|GO:0008152 MC49_RS11100 43eb334fe98e7cd4060e2815b28528bc 760 TIGRFAM TIGR01255 pyr_form_ly_1: formate acetyltransferase 11 760 0.0 T 29-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 MC49_RS11100 43eb334fe98e7cd4060e2815b28528bc 760 SUPERFAMILY SSF51998 4 759 1.1E-286 T 29-03-2018 MC49_RS12935 da289957f214617fa18676d000a8152f 108 Gene3D G3DSA:1.10.260.40 15 95 2.9E-4 T 29-03-2018 MC49_RS14655 215f1dc5926b9f9a2ee9d0fa025f583c 301 SUPERFAMILY SSF103481 193 297 2.22E-15 T 29-03-2018 MC49_RS14655 215f1dc5926b9f9a2ee9d0fa025f583c 301 SUPERFAMILY SSF103481 45 148 4.97E-12 T 29-03-2018 MC49_RS14655 215f1dc5926b9f9a2ee9d0fa025f583c 301 Pfam PF00892 EamA-like transporter family 12 145 9.5E-21 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MC49_RS14655 215f1dc5926b9f9a2ee9d0fa025f583c 301 Pfam PF00892 EamA-like transporter family 156 293 1.5E-24 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MC49_RS06450 ab8eed30440c7665205eb34d0543e8ca 478 TIGRFAM TIGR00835 agcS: amino acid carrier protein 16 453 1.1E-104 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MC49_RS06450 ab8eed30440c7665205eb34d0543e8ca 478 PRINTS PR00175 Sodium/alanine symporter signature 219 238 8.8E-30 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MC49_RS06450 ab8eed30440c7665205eb34d0543e8ca 478 PRINTS PR00175 Sodium/alanine symporter signature 359 381 8.8E-30 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MC49_RS06450 ab8eed30440c7665205eb34d0543e8ca 478 PRINTS PR00175 Sodium/alanine symporter signature 99 121 8.8E-30 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MC49_RS06450 ab8eed30440c7665205eb34d0543e8ca 478 PRINTS PR00175 Sodium/alanine symporter signature 191 209 8.8E-30 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MC49_RS06450 ab8eed30440c7665205eb34d0543e8ca 478 PRINTS PR00175 Sodium/alanine symporter signature 313 331 8.8E-30 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MC49_RS06450 ab8eed30440c7665205eb34d0543e8ca 478 PRINTS PR00175 Sodium/alanine symporter signature 423 443 8.8E-30 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MC49_RS06450 ab8eed30440c7665205eb34d0543e8ca 478 Pfam PF01235 Sodium:alanine symporter family 65 457 3.1E-99 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MC49_RS10935 61d1193bf9ae010e09bc60000d089cf7 455 Pfam PF03313 Serine dehydratase alpha chain 184 448 1.6E-94 T 29-03-2018 IPR005130 Serine dehydratase-like, alpha subunit MC49_RS10935 61d1193bf9ae010e09bc60000d089cf7 455 Pfam PF03315 Serine dehydratase beta chain 3 155 1.4E-56 T 29-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 MC49_RS10935 61d1193bf9ae010e09bc60000d089cf7 455 Gene3D G3DSA:1.10.4100.10 261 449 6.7E-31 T 29-03-2018 MC49_RS10935 61d1193bf9ae010e09bc60000d089cf7 455 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 2 451 2.1E-222 T 29-03-2018 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 MC49_RS10935 61d1193bf9ae010e09bc60000d089cf7 455 Gene3D G3DSA:3.30.1330.90 10 158 1.5E-51 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 MC49_RS10935 61d1193bf9ae010e09bc60000d089cf7 455 SUPERFAMILY SSF143548 16 158 2.2E-45 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 MC49_RS01955 9f95920464b0d038a0ef87b2ad064d24 90 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 29-03-2018 IPR019812 Hydrogenase assembly chaperone, conserved site MC49_RS01955 9f95920464b0d038a0ef87b2ad064d24 90 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 63 75 7.8E-24 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC MC49_RS01955 9f95920464b0d038a0ef87b2ad064d24 90 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 45 61 7.8E-24 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC MC49_RS01955 9f95920464b0d038a0ef87b2ad064d24 90 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 7.8E-24 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC MC49_RS01955 9f95920464b0d038a0ef87b2ad064d24 90 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 20 36 7.8E-24 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC MC49_RS01955 9f95920464b0d038a0ef87b2ad064d24 90 Pfam PF01455 HupF/HypC family 1 72 1.6E-26 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC MC49_RS01955 9f95920464b0d038a0ef87b2ad064d24 90 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 81 2.7E-28 T 29-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC MC49_RS01955 9f95920464b0d038a0ef87b2ad064d24 90 SUPERFAMILY SSF159127 1 85 1.31E-25 T 29-03-2018 MC49_RS18005 e07ac29b365665118991d78bbd7aa379 323 SUPERFAMILY SSF64383 185 317 4.18E-44 T 29-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 MC49_RS18005 e07ac29b365665118991d78bbd7aa379 323 TIGRFAM TIGR02205 septum_zipA: cell division protein ZipA 3 314 1.3E-80 T 29-03-2018 IPR011919 Cell division protein ZipA GO:0007049|GO:0016021|GO:0090529 MC49_RS18005 e07ac29b365665118991d78bbd7aa379 323 Gene3D G3DSA:3.30.1400.10 185 317 1.1E-49 T 29-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 MC49_RS18005 e07ac29b365665118991d78bbd7aa379 323 SMART SM00771 184 314 1.0E-68 T 29-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 MC49_RS18005 e07ac29b365665118991d78bbd7aa379 323 ProDom PD035754 CELL DIVISION MEMBRANE ZIPA SEPTATION TRANSMEMBRANE HOMOLOG INNER CYCLE ZIPA 187 321 5.0E-52 T 29-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 MC49_RS18005 e07ac29b365665118991d78bbd7aa379 323 Hamap MF_00509 Cell division protein ZipA [zipA]. 2 316 24.158 T 29-03-2018 IPR011919 Cell division protein ZipA GO:0007049|GO:0016021|GO:0090529 MC49_RS18005 e07ac29b365665118991d78bbd7aa379 323 Pfam PF04354 ZipA, C-terminal FtsZ-binding domain 187 313 3.4E-47 T 29-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 MC49_RS10600 1bd35ff989a8db338b80fddb6e172ec4 302 SUPERFAMILY SSF142338 11 295 5.62E-80 T 29-03-2018 MC49_RS10600 1bd35ff989a8db338b80fddb6e172ec4 302 Gene3D G3DSA:3.40.50.10680 89 297 3.8E-35 T 29-03-2018 MC49_RS10600 1bd35ff989a8db338b80fddb6e172ec4 302 Pfam PF01933 Uncharacterised protein family UPF0052 12 288 4.0E-73 T 29-03-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 MC49_RS10600 1bd35ff989a8db338b80fddb6e172ec4 302 Hamap MF_00973 Gluconeogenesis factor. 8 300 30.528 T 29-03-2018 IPR010119 Gluconeogenesis factor MC49_RS10600 1bd35ff989a8db338b80fddb6e172ec4 302 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 12 258 6.9E-94 T 29-03-2018 IPR010119 Gluconeogenesis factor MC49_RS08520 e6861f10b114b934c130430f1c2796d8 846 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 290 9.5E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS08520 e6861f10b114b934c130430f1c2796d8 846 Pfam PF04324 BFD-like [2Fe-2S] binding domain 424 471 4.2E-16 T 29-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain MC49_RS08520 e6861f10b114b934c130430f1c2796d8 846 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 6 801 0.0 T 29-03-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 MC49_RS08520 e6861f10b114b934c130430f1c2796d8 846 PRINTS PR00397 Sirohaem Fe-binding site signature 636 654 1.2E-5 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MC49_RS08520 e6861f10b114b934c130430f1c2796d8 846 PRINTS PR00397 Sirohaem Fe-binding site signature 679 697 1.2E-5 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MC49_RS08520 e6861f10b114b934c130430f1c2796d8 846 Gene3D G3DSA:3.50.50.60 1 101 2.5E-10 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS08520 e6861f10b114b934c130430f1c2796d8 846 Gene3D G3DSA:3.30.413.10 631 814 7.1E-37 T 29-03-2018 MC49_RS08520 e6861f10b114b934c130430f1c2796d8 846 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 633 757 5.2E-16 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MC49_RS08520 e6861f10b114b934c130430f1c2796d8 846 SUPERFAMILY SSF56014 633 808 1.3E-45 T 29-03-2018 MC49_RS08520 e6861f10b114b934c130430f1c2796d8 846 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 277 284 1.2E-11 T 29-03-2018 MC49_RS08520 e6861f10b114b934c130430f1c2796d8 846 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 236 250 1.2E-11 T 29-03-2018 MC49_RS08520 e6861f10b114b934c130430f1c2796d8 846 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 105 114 1.2E-11 T 29-03-2018 MC49_RS08520 e6861f10b114b934c130430f1c2796d8 846 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 1.2E-11 T 29-03-2018 MC49_RS08520 e6861f10b114b934c130430f1c2796d8 846 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 1.1E-15 T 29-03-2018 MC49_RS08520 e6861f10b114b934c130430f1c2796d8 846 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 284 1.1E-15 T 29-03-2018 MC49_RS08520 e6861f10b114b934c130430f1c2796d8 846 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.1E-15 T 29-03-2018 MC49_RS08520 e6861f10b114b934c130430f1c2796d8 846 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 235 251 1.1E-15 T 29-03-2018 MC49_RS08520 e6861f10b114b934c130430f1c2796d8 846 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 1.1E-15 T 29-03-2018 MC49_RS08520 e6861f10b114b934c130430f1c2796d8 846 Gene3D G3DSA:3.50.50.60 247 319 3.0E-10 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS08520 e6861f10b114b934c130430f1c2796d8 846 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 560 622 3.2E-11 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MC49_RS08520 e6861f10b114b934c130430f1c2796d8 846 SUPERFAMILY SSF55124 502 627 2.45E-29 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MC49_RS08520 e6861f10b114b934c130430f1c2796d8 846 Gene3D G3DSA:3.50.50.60 102 244 2.3E-30 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS08520 e6861f10b114b934c130430f1c2796d8 846 Gene3D G3DSA:3.90.480.10 498 629 1.2E-6 T 29-03-2018 MC49_RS08520 e6861f10b114b934c130430f1c2796d8 846 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 679 695 - T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MC49_RS08520 e6861f10b114b934c130430f1c2796d8 846 PIRSF PIRSF037149 1 835 0.0 T 29-03-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 MC49_RS08520 e6861f10b114b934c130430f1c2796d8 846 SUPERFAMILY SSF51905 2 311 4.09E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS03475 78eee356c3a1714fffc31e84db82e4e0 156 SUPERFAMILY SSF55252 82 151 1.57E-18 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 MC49_RS03475 78eee356c3a1714fffc31e84db82e4e0 156 Gene3D G3DSA:1.10.10.10 8 69 1.3E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS03475 78eee356c3a1714fffc31e84db82e4e0 156 Pfam PF01316 Arginine repressor, DNA binding domain 6 74 1.1E-24 T 29-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 MC49_RS03475 78eee356c3a1714fffc31e84db82e4e0 156 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 89 153 1.0E-25 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 MC49_RS03475 78eee356c3a1714fffc31e84db82e4e0 156 TIGRFAM TIGR01529 argR_whole: arginine repressor 11 151 8.5E-46 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 MC49_RS03475 78eee356c3a1714fffc31e84db82e4e0 156 Gene3D G3DSA:3.30.1360.40 76 151 1.0E-24 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 MC49_RS03475 78eee356c3a1714fffc31e84db82e4e0 156 PRINTS PR01467 Bacterial arginine repressor signature 121 136 7.3E-24 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 MC49_RS03475 78eee356c3a1714fffc31e84db82e4e0 156 PRINTS PR01467 Bacterial arginine repressor signature 25 38 7.3E-24 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 MC49_RS03475 78eee356c3a1714fffc31e84db82e4e0 156 PRINTS PR01467 Bacterial arginine repressor signature 90 103 7.3E-24 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 MC49_RS03475 78eee356c3a1714fffc31e84db82e4e0 156 PRINTS PR01467 Bacterial arginine repressor signature 42 57 7.3E-24 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 MC49_RS03475 78eee356c3a1714fffc31e84db82e4e0 156 Hamap MF_00173 Arginine repressor [argR]. 1 155 59.546 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 MC49_RS03475 78eee356c3a1714fffc31e84db82e4e0 156 SUPERFAMILY SSF46785 3 76 3.36E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS03475 78eee356c3a1714fffc31e84db82e4e0 156 Pfam PF02863 Arginine repressor, C-terminal domain 82 148 1.4E-21 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 MC49_RS13625 73d1cd05275b10b4f988c4def8588ad0 285 TIGRFAM TIGR00828 EIID-AGA: PTS system, mannose/fructose/sorbose family, IID component 12 283 2.5E-137 T 29-03-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 MC49_RS13625 73d1cd05275b10b4f988c4def8588ad0 285 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 13 283 4.8E-110 T 29-03-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 MC49_RS07850 c59ce73d1e9c8b2eecfa188dd3e545f7 748 Pfam PF05524 PEP-utilising enzyme, N-terminal 173 294 4.9E-22 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 MC49_RS07850 c59ce73d1e9c8b2eecfa188dd3e545f7 748 SUPERFAMILY SSF47831 202 309 5.36E-25 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 MC49_RS07850 c59ce73d1e9c8b2eecfa188dd3e545f7 748 Gene3D G3DSA:3.30.450.40 1 161 3.2E-32 T 29-03-2018 IPR029016 GAF domain-like MC49_RS07850 c59ce73d1e9c8b2eecfa188dd3e545f7 748 Gene3D G3DSA:3.20.20.60 421 739 4.0E-77 T 29-03-2018 MC49_RS07850 c59ce73d1e9c8b2eecfa188dd3e545f7 748 SMART SM00065 17 164 7.7E-25 T 29-03-2018 IPR003018 GAF domain GO:0005515 MC49_RS07850 c59ce73d1e9c8b2eecfa188dd3e545f7 748 SUPERFAMILY SSF55781 2 158 1.35E-32 T 29-03-2018 IPR029016 GAF domain-like MC49_RS07850 c59ce73d1e9c8b2eecfa188dd3e545f7 748 Pfam PF01590 GAF domain 17 152 1.6E-16 T 29-03-2018 IPR003018 GAF domain GO:0005515 MC49_RS07850 c59ce73d1e9c8b2eecfa188dd3e545f7 748 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 424 707 6.1E-92 T 29-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 MC49_RS07850 c59ce73d1e9c8b2eecfa188dd3e545f7 748 Gene3D G3DSA:1.10.274.10 196 303 9.9E-28 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 MC49_RS07850 c59ce73d1e9c8b2eecfa188dd3e545f7 748 SUPERFAMILY SSF52009 293 412 4.06E-25 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MC49_RS07850 c59ce73d1e9c8b2eecfa188dd3e545f7 748 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 613 628 4.7E-22 T 29-03-2018 MC49_RS07850 c59ce73d1e9c8b2eecfa188dd3e545f7 748 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 666 678 4.7E-22 T 29-03-2018 MC49_RS07850 c59ce73d1e9c8b2eecfa188dd3e545f7 748 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 459 478 4.7E-22 T 29-03-2018 MC49_RS07850 c59ce73d1e9c8b2eecfa188dd3e545f7 748 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 630 645 4.7E-22 T 29-03-2018 MC49_RS07850 c59ce73d1e9c8b2eecfa188dd3e545f7 748 SUPERFAMILY SSF51621 423 713 4.19E-91 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MC49_RS07850 c59ce73d1e9c8b2eecfa188dd3e545f7 748 Gene3D G3DSA:3.50.30.10 304 420 1.8E-19 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MC49_RS07850 c59ce73d1e9c8b2eecfa188dd3e545f7 748 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 172 728 2.1E-115 T 29-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 MC49_RS07850 c59ce73d1e9c8b2eecfa188dd3e545f7 748 Pfam PF00391 PEP-utilising enzyme, mobile domain 320 391 4.5E-15 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MC49_RS07850 c59ce73d1e9c8b2eecfa188dd3e545f7 748 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 613 631 - T 29-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 MC49_RS07235 c4050deb0ec1c90b590cf57243b6556d 493 Pfam PF11806 Domain of unknown function (DUF3327) 141 225 2.5E-11 T 29-03-2018 IPR021764 Enterochelin esterase, N-terminal GO:0005506|GO:0005737|GO:0006826|GO:0008849 MC49_RS07235 c4050deb0ec1c90b590cf57243b6556d 493 SUPERFAMILY SSF81296 117 227 1.96E-25 T 29-03-2018 IPR014756 Immunoglobulin E-set MC49_RS07235 c4050deb0ec1c90b590cf57243b6556d 493 SUPERFAMILY SSF53474 253 486 7.16E-39 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS07235 c4050deb0ec1c90b590cf57243b6556d 493 Gene3D G3DSA:2.60.40.10 116 231 3.0E-26 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS07235 c4050deb0ec1c90b590cf57243b6556d 493 Pfam PF00756 Putative esterase 267 485 7.1E-24 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 MC49_RS07235 c4050deb0ec1c90b590cf57243b6556d 493 Gene3D G3DSA:3.40.50.1820 246 493 3.0E-23 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS11475 79b675f34909ed02d4e19141c7aea429 215 Gene3D G3DSA:2.60.40.10 134 215 4.3E-23 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS11475 79b675f34909ed02d4e19141c7aea429 215 Gene3D G3DSA:2.60.40.10 14 133 3.4E-33 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS11475 79b675f34909ed02d4e19141c7aea429 215 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 154 206 2.6E-14 T 29-03-2018 IPR016148 Pili assembly chaperone, C-terminal MC49_RS11475 79b675f34909ed02d4e19141c7aea429 215 SUPERFAMILY SSF49354 11 132 8.63E-37 T 29-03-2018 IPR008962 PapD-like MC49_RS11475 79b675f34909ed02d4e19141c7aea429 215 ProSitePatterns PS00635 Gram-negative pili assembly chaperone signature. 86 103 - T 29-03-2018 IPR018046 Pili assembly chaperone, conserved site MC49_RS11475 79b675f34909ed02d4e19141c7aea429 215 PRINTS PR00969 Pili chaperone signature 149 164 1.1E-35 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS11475 79b675f34909ed02d4e19141c7aea429 215 PRINTS PR00969 Pili chaperone signature 59 80 1.1E-35 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS11475 79b675f34909ed02d4e19141c7aea429 215 PRINTS PR00969 Pili chaperone signature 87 104 1.1E-35 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS11475 79b675f34909ed02d4e19141c7aea429 215 PRINTS PR00969 Pili chaperone signature 15 24 1.1E-35 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS11475 79b675f34909ed02d4e19141c7aea429 215 PRINTS PR00969 Pili chaperone signature 114 129 1.1E-35 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS11475 79b675f34909ed02d4e19141c7aea429 215 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 14 132 9.3E-39 T 29-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 MC49_RS11475 79b675f34909ed02d4e19141c7aea429 215 SUPERFAMILY SSF49584 137 208 5.49E-20 T 29-03-2018 IPR016148 Pili assembly chaperone, C-terminal MC49_RS03465 0c0dc3d74b98bc88c5f1ee00605a96b4 88 Pfam PF13693 Winged helix-turn-helix DNA-binding 7 81 8.4E-38 T 29-03-2018 MC49_RS03465 0c0dc3d74b98bc88c5f1ee00605a96b4 88 SUPERFAMILY SSF47413 4 71 3.21E-30 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS03465 0c0dc3d74b98bc88c5f1ee00605a96b4 88 Gene3D G3DSA:1.10.260.40 1 73 1.8E-15 T 29-03-2018 MC49_RS00495 13250e34829afa49f26f9afd67b6b924 261 Pfam PF00106 short chain dehydrogenase 3 190 1.5E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS00495 13250e34829afa49f26f9afd67b6b924 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 9.3E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS00495 13250e34829afa49f26f9afd67b6b924 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 9.3E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS00495 13250e34829afa49f26f9afd67b6b924 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 9.3E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS00495 13250e34829afa49f26f9afd67b6b924 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 9.0E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS00495 13250e34829afa49f26f9afd67b6b924 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 9.0E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS00495 13250e34829afa49f26f9afd67b6b924 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 9.0E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS00495 13250e34829afa49f26f9afd67b6b924 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 9.0E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS00495 13250e34829afa49f26f9afd67b6b924 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 9.0E-22 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS00495 13250e34829afa49f26f9afd67b6b924 261 Gene3D G3DSA:3.40.50.720 2 261 1.1E-60 T 29-03-2018 MC49_RS00495 13250e34829afa49f26f9afd67b6b924 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 133 161 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MC49_RS00495 13250e34829afa49f26f9afd67b6b924 261 SUPERFAMILY SSF51735 2 253 5.29E-62 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS00495 13250e34829afa49f26f9afd67b6b924 261 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 182 7.3E-4 T 29-03-2018 MC49_RS01465 a99d2723ea1ea5922215802b6ae56846 375 Pfam PF03969 AFG1-like ATPase 3 370 1.0E-144 T 29-03-2018 IPR005654 ATPase, AFG1-like GO:0005524 MC49_RS01465 a99d2723ea1ea5922215802b6ae56846 375 Hamap MF_01919 Cell division protein ZapE [zapE]. 3 375 51.822 T 29-03-2018 IPR030870 Cell division protein ZapE GO:0016887|GO:0051301 MC49_RS01465 a99d2723ea1ea5922215802b6ae56846 375 Gene3D G3DSA:3.40.50.300 22 369 1.2E-12 T 29-03-2018 MC49_RS01465 a99d2723ea1ea5922215802b6ae56846 375 SUPERFAMILY SSF52540 70 206 1.03E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS15705 e8b7f33aaed9bcd76c6decac635b5ff1 206 Pfam PF01810 LysE type translocator 15 202 2.2E-46 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MC49_RS15705 e8b7f33aaed9bcd76c6decac635b5ff1 206 PIRSF PIRSF006324 1 205 1.2E-52 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MC49_RS09760 e6b7544d51c8750bf5a933455dd5acea 486 Pfam PF01546 Peptidase family M20/M25/M40 73 480 1.0E-20 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 MC49_RS09760 e6b7544d51c8750bf5a933455dd5acea 486 SUPERFAMILY SSF53187 10 182 5.19E-64 T 29-03-2018 MC49_RS09760 e6b7544d51c8750bf5a933455dd5acea 486 SUPERFAMILY SSF53187 397 482 5.19E-64 T 29-03-2018 MC49_RS09760 e6b7544d51c8750bf5a933455dd5acea 486 PIRSF PIRSF016599 1 485 1.0E-210 T 29-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MC49_RS09760 e6b7544d51c8750bf5a933455dd5acea 486 PRINTS PR00934 X-His dipeptidase (M25) signature 80 99 3.5E-94 T 29-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MC49_RS09760 e6b7544d51c8750bf5a933455dd5acea 486 PRINTS PR00934 X-His dipeptidase (M25) signature 363 381 3.5E-94 T 29-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MC49_RS09760 e6b7544d51c8750bf5a933455dd5acea 486 PRINTS PR00934 X-His dipeptidase (M25) signature 206 223 3.5E-94 T 29-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MC49_RS09760 e6b7544d51c8750bf5a933455dd5acea 486 PRINTS PR00934 X-His dipeptidase (M25) signature 251 270 3.5E-94 T 29-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MC49_RS09760 e6b7544d51c8750bf5a933455dd5acea 486 PRINTS PR00934 X-His dipeptidase (M25) signature 101 119 3.5E-94 T 29-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MC49_RS09760 e6b7544d51c8750bf5a933455dd5acea 486 PRINTS PR00934 X-His dipeptidase (M25) signature 450 472 3.5E-94 T 29-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MC49_RS09760 e6b7544d51c8750bf5a933455dd5acea 486 PRINTS PR00934 X-His dipeptidase (M25) signature 135 152 3.5E-94 T 29-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MC49_RS09760 e6b7544d51c8750bf5a933455dd5acea 486 PRINTS PR00934 X-His dipeptidase (M25) signature 159 177 3.5E-94 T 29-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MC49_RS09760 e6b7544d51c8750bf5a933455dd5acea 486 PRINTS PR00934 X-His dipeptidase (M25) signature 428 444 3.5E-94 T 29-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MC49_RS09760 e6b7544d51c8750bf5a933455dd5acea 486 Gene3D G3DSA:3.40.630.10 5 484 1.5E-49 T 29-03-2018 MC49_RS09760 e6b7544d51c8750bf5a933455dd5acea 486 Pfam PF07687 Peptidase dimerisation domain 200 293 3.2E-6 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain MC49_RS09760 e6b7544d51c8750bf5a933455dd5acea 486 TIGRFAM TIGR01893 aa-his-dipept: Xaa-His dipeptidase 9 482 2.1E-180 T 29-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 MC49_RS05790 d611b1abccf40593b549b0a84d49f0b7 325 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 5 325 45.073 T 29-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 MC49_RS05790 d611b1abccf40593b549b0a84d49f0b7 325 ProSitePatterns PS00433 Phosphofructokinase signature. 249 267 - T 29-03-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MC49_RS05790 d611b1abccf40593b549b0a84d49f0b7 325 Pfam PF00365 Phosphofructokinase 7 280 2.5E-104 T 29-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MC49_RS05790 d611b1abccf40593b549b0a84d49f0b7 325 Gene3D G3DSA:3.40.50.450 1 216 4.8E-81 T 29-03-2018 MC49_RS05790 d611b1abccf40593b549b0a84d49f0b7 325 PIRSF PIRSF000532 4 325 1.7E-126 T 29-03-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 MC49_RS05790 d611b1abccf40593b549b0a84d49f0b7 325 SUPERFAMILY SSF53784 2 318 6.8E-111 T 29-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MC49_RS05790 d611b1abccf40593b549b0a84d49f0b7 325 Gene3D G3DSA:3.40.50.450 217 315 7.9E-9 T 29-03-2018 MC49_RS05790 d611b1abccf40593b549b0a84d49f0b7 325 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 162 178 6.4E-81 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MC49_RS05790 d611b1abccf40593b549b0a84d49f0b7 325 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 142 160 6.4E-81 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MC49_RS05790 d611b1abccf40593b549b0a84d49f0b7 325 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 10 29 6.4E-81 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MC49_RS05790 d611b1abccf40593b549b0a84d49f0b7 325 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 97 113 6.4E-81 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MC49_RS05790 d611b1abccf40593b549b0a84d49f0b7 325 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 35 48 6.4E-81 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MC49_RS05790 d611b1abccf40593b549b0a84d49f0b7 325 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 124 141 6.4E-81 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MC49_RS05790 d611b1abccf40593b549b0a84d49f0b7 325 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 180 197 6.4E-81 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MC49_RS05790 d611b1abccf40593b549b0a84d49f0b7 325 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 245 267 6.4E-81 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MC49_RS05790 d611b1abccf40593b549b0a84d49f0b7 325 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 218 230 6.4E-81 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MC49_RS05790 d611b1abccf40593b549b0a84d49f0b7 325 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 7 305 2.2E-124 T 29-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 MC49_RS08535 c8aa96d8f6a265a1808d4cde6cce16ee 236 Pfam PF07702 UTRA domain 92 229 7.4E-19 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MC49_RS08535 c8aa96d8f6a265a1808d4cde6cce16ee 236 SUPERFAMILY SSF64288 58 235 2.04E-23 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain MC49_RS08535 c8aa96d8f6a265a1808d4cde6cce16ee 236 SMART SM00866 91 231 8.0E-8 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MC49_RS08535 c8aa96d8f6a265a1808d4cde6cce16ee 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 30 44 4.3E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MC49_RS08535 c8aa96d8f6a265a1808d4cde6cce16ee 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 60 4.3E-8 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MC49_RS08535 c8aa96d8f6a265a1808d4cde6cce16ee 236 SMART SM00345 11 70 3.6E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MC49_RS08535 c8aa96d8f6a265a1808d4cde6cce16ee 236 Gene3D G3DSA:1.10.10.10 1 71 1.4E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS08535 c8aa96d8f6a265a1808d4cde6cce16ee 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 69 1.7E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MC49_RS08535 c8aa96d8f6a265a1808d4cde6cce16ee 236 Gene3D G3DSA:3.40.1410.10 81 236 5.9E-18 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain MC49_RS08535 c8aa96d8f6a265a1808d4cde6cce16ee 236 SUPERFAMILY SSF46785 5 71 1.86E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS05165 027dd3210c78d629e55e647d1c71c7e6 513 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 512 50.146 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05165 027dd3210c78d629e55e647d1c71c7e6 513 Gene3D G3DSA:1.20.150.20 384 510 2.8E-47 T 29-03-2018 MC49_RS05165 027dd3210c78d629e55e647d1c71c7e6 513 Gene3D G3DSA:3.40.50.300 83 375 4.9E-112 T 29-03-2018 MC49_RS05165 027dd3210c78d629e55e647d1c71c7e6 513 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 2 512 3.2E-260 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05165 027dd3210c78d629e55e647d1c71c7e6 513 SUPERFAMILY SSF52540 96 381 8.86E-95 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS05165 027dd3210c78d629e55e647d1c71c7e6 513 SUPERFAMILY SSF47917 383 511 3.92E-46 T 29-03-2018 MC49_RS05165 027dd3210c78d629e55e647d1c71c7e6 513 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 375 2.3E-73 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MC49_RS05165 027dd3210c78d629e55e647d1c71c7e6 513 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 29 92 1.7E-13 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MC49_RS05165 027dd3210c78d629e55e647d1c71c7e6 513 SUPERFAMILY SSF50615 10 94 1.2E-25 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MC49_RS05165 027dd3210c78d629e55e647d1c71c7e6 513 Gene3D G3DSA:2.40.30.20 3 82 9.5E-28 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05165 027dd3210c78d629e55e647d1c71c7e6 513 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 382 507 5.0E-46 T 29-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05165 027dd3210c78d629e55e647d1c71c7e6 513 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 366 375 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MC49_RS00025 9135adcd213be2b5b48cd2ce5f2b339c 297 SUPERFAMILY SSF51182 14 283 3.75E-71 T 29-03-2018 IPR011051 RmlC-like cupin domain MC49_RS00025 9135adcd213be2b5b48cd2ce5f2b339c 297 PIRSF PIRSF006232 4 285 1.5E-73 T 29-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 MC49_RS00025 9135adcd213be2b5b48cd2ce5f2b339c 297 Gene3D G3DSA:2.60.120.10 1 248 2.2E-60 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MC49_RS00025 9135adcd213be2b5b48cd2ce5f2b339c 297 Pfam PF05726 Pirin C-terminal cupin domain 175 273 1.2E-17 T 29-03-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 MC49_RS00025 9135adcd213be2b5b48cd2ce5f2b339c 297 Pfam PF02678 Pirin 23 123 4.2E-30 T 29-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 MC49_RS01475 f7761996e9b3cc26528f3f95ee889649 464 Gene3D G3DSA:2.30.42.10 372 461 8.8E-16 T 29-03-2018 MC49_RS01475 f7761996e9b3cc26528f3f95ee889649 464 SUPERFAMILY SSF50494 42 264 3.86E-65 T 29-03-2018 IPR009003 Peptidase S1, PA clan MC49_RS01475 f7761996e9b3cc26528f3f95ee889649 464 Gene3D G3DSA:2.40.10.10 145 262 7.6E-42 T 29-03-2018 MC49_RS01475 f7761996e9b3cc26528f3f95ee889649 464 PRINTS PR00834 HtrA/DegQ protease family signature 226 243 1.1E-57 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MC49_RS01475 f7761996e9b3cc26528f3f95ee889649 464 PRINTS PR00834 HtrA/DegQ protease family signature 312 324 1.1E-57 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MC49_RS01475 f7761996e9b3cc26528f3f95ee889649 464 PRINTS PR00834 HtrA/DegQ protease family signature 169 193 1.1E-57 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MC49_RS01475 f7761996e9b3cc26528f3f95ee889649 464 PRINTS PR00834 HtrA/DegQ protease family signature 204 221 1.1E-57 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MC49_RS01475 f7761996e9b3cc26528f3f95ee889649 464 PRINTS PR00834 HtrA/DegQ protease family signature 107 119 1.1E-57 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MC49_RS01475 f7761996e9b3cc26528f3f95ee889649 464 PRINTS PR00834 HtrA/DegQ protease family signature 128 148 1.1E-57 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MC49_RS01475 f7761996e9b3cc26528f3f95ee889649 464 Pfam PF13365 Trypsin-like peptidase domain 97 233 7.7E-33 T 29-03-2018 MC49_RS01475 f7761996e9b3cc26528f3f95ee889649 464 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 44 458 6.3E-157 T 29-03-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 MC49_RS01475 f7761996e9b3cc26528f3f95ee889649 464 SMART SM00228 374 452 8.0E-9 T 29-03-2018 IPR001478 PDZ domain GO:0005515 MC49_RS01475 f7761996e9b3cc26528f3f95ee889649 464 SMART SM00228 272 354 2.0E-14 T 29-03-2018 IPR001478 PDZ domain GO:0005515 MC49_RS01475 f7761996e9b3cc26528f3f95ee889649 464 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 382 449 1.4E-9 T 29-03-2018 IPR001478 PDZ domain GO:0005515 MC49_RS01475 f7761996e9b3cc26528f3f95ee889649 464 SUPERFAMILY SSF50156 390 456 7.62E-15 T 29-03-2018 IPR001478 PDZ domain GO:0005515 MC49_RS01475 f7761996e9b3cc26528f3f95ee889649 464 Gene3D G3DSA:2.30.42.10 267 371 1.7E-26 T 29-03-2018 MC49_RS01475 f7761996e9b3cc26528f3f95ee889649 464 SUPERFAMILY SSF50156 230 355 4.21E-24 T 29-03-2018 IPR001478 PDZ domain GO:0005515 MC49_RS01475 f7761996e9b3cc26528f3f95ee889649 464 Pfam PF13180 PDZ domain 291 362 1.5E-16 T 29-03-2018 IPR001478 PDZ domain GO:0005515 MC49_RS01475 f7761996e9b3cc26528f3f95ee889649 464 Gene3D G3DSA:2.40.10.10 31 144 1.7E-33 T 29-03-2018 MC49_RS18975 44451ec90a286cadb131d8ed4ae4fee4 215 SUPERFAMILY SSF53639 1 211 1.37E-62 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal MC49_RS18975 44451ec90a286cadb131d8ed4ae4fee4 215 Hamap MF_00987 L-fuculose phosphate aldolase [fucA]. 1 215 55.647 T 29-03-2018 IPR004782 L-fucose phosphate aldolase GO:0006004|GO:0008270|GO:0008738 KEGG: 00051+4.1.2.17|MetaCyc: PWY-5197 MC49_RS18975 44451ec90a286cadb131d8ed4ae4fee4 215 SMART SM01007 8 182 1.5E-60 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal MC49_RS18975 44451ec90a286cadb131d8ed4ae4fee4 215 Gene3D G3DSA:3.40.225.10 1 213 5.2E-57 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal MC49_RS18975 44451ec90a286cadb131d8ed4ae4fee4 215 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 8 181 6.2E-45 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal MC49_RS07575 e61d6f2c7517cc3f989b2f27e27864c7 381 SUPERFAMILY SSF49493 116 171 5.76E-19 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 MC49_RS07575 e61d6f2c7517cc3f989b2f27e27864c7 381 SUPERFAMILY SSF49493 215 261 5.76E-19 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 MC49_RS07575 e61d6f2c7517cc3f989b2f27e27864c7 381 Gene3D G3DSA:1.10.287.110 1 120 5.7E-38 T 29-03-2018 IPR001623 DnaJ domain MC49_RS07575 e61d6f2c7517cc3f989b2f27e27864c7 381 Pfam PF00226 DnaJ domain 5 67 2.2E-28 T 29-03-2018 IPR001623 DnaJ domain MC49_RS07575 e61d6f2c7517cc3f989b2f27e27864c7 381 SUPERFAMILY SSF49493 261 346 2.22E-21 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 MC49_RS07575 e61d6f2c7517cc3f989b2f27e27864c7 381 Gene3D G3DSA:2.10.230.10 149 195 5.2E-15 T 29-03-2018 MC49_RS07575 e61d6f2c7517cc3f989b2f27e27864c7 381 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 351 1.4E-143 T 29-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 MC49_RS07575 e61d6f2c7517cc3f989b2f27e27864c7 381 Pfam PF01556 DnaJ C terminal domain 123 335 1.1E-43 T 29-03-2018 IPR002939 Chaperone DnaJ, C-terminal MC49_RS07575 e61d6f2c7517cc3f989b2f27e27864c7 381 Gene3D G3DSA:2.60.260.20 196 256 1.0E-18 T 29-03-2018 MC49_RS07575 e61d6f2c7517cc3f989b2f27e27864c7 381 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 375 42.91 T 29-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 MC49_RS07575 e61d6f2c7517cc3f989b2f27e27864c7 381 Gene3D G3DSA:2.60.260.20 257 368 9.1E-28 T 29-03-2018 MC49_RS07575 e61d6f2c7517cc3f989b2f27e27864c7 381 ProSitePatterns PS00636 Nt-dnaJ domain signature. 47 66 - T 29-03-2018 IPR018253 DnaJ domain, conserved site MC49_RS07575 e61d6f2c7517cc3f989b2f27e27864c7 381 SUPERFAMILY SSF57938 136 212 1.02E-23 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 MC49_RS07575 e61d6f2c7517cc3f989b2f27e27864c7 381 SUPERFAMILY SSF46565 1 108 9.81E-37 T 29-03-2018 IPR001623 DnaJ domain MC49_RS07575 e61d6f2c7517cc3f989b2f27e27864c7 381 SMART SM00271 4 62 2.3E-31 T 29-03-2018 IPR001623 DnaJ domain MC49_RS07575 e61d6f2c7517cc3f989b2f27e27864c7 381 Pfam PF00684 DnaJ central domain 149 209 8.9E-16 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 MC49_RS07575 e61d6f2c7517cc3f989b2f27e27864c7 381 PRINTS PR00625 DnaJ domain signature 42 62 5.5E-34 T 29-03-2018 IPR001623 DnaJ domain MC49_RS07575 e61d6f2c7517cc3f989b2f27e27864c7 381 PRINTS PR00625 DnaJ domain signature 25 40 5.5E-34 T 29-03-2018 IPR001623 DnaJ domain MC49_RS07575 e61d6f2c7517cc3f989b2f27e27864c7 381 PRINTS PR00625 DnaJ domain signature 7 25 5.5E-34 T 29-03-2018 IPR001623 DnaJ domain MC49_RS07575 e61d6f2c7517cc3f989b2f27e27864c7 381 PRINTS PR00625 DnaJ domain signature 62 81 5.5E-34 T 29-03-2018 IPR001623 DnaJ domain MC49_RS11825 3f99d5c6fad0ad97431090cabd788bad 597 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 42 57 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site MC49_RS11825 3f99d5c6fad0ad97431090cabd788bad 597 Gene3D G3DSA:3.40.50.300 2 185 5.5E-36 T 29-03-2018 MC49_RS11825 3f99d5c6fad0ad97431090cabd788bad 597 Hamap MF_00071 Elongation factor 4 [lepA]. 1 597 305.047 T 29-03-2018 IPR006297 Elongation factor 4 GO:0005525 MC49_RS11825 3f99d5c6fad0ad97431090cabd788bad 597 Pfam PF06421 GTP-binding protein LepA C-terminus 487 592 4.6E-48 T 29-03-2018 IPR013842 GTP-binding protein LepA, C-terminal MC49_RS11825 3f99d5c6fad0ad97431090cabd788bad 597 SUPERFAMILY SSF54980 292 370 1.94E-18 T 29-03-2018 IPR035647 EF-G domain III/V-like MC49_RS11825 3f99d5c6fad0ad97431090cabd788bad 597 Gene3D G3DSA:2.40.30.10 188 287 3.8E-25 T 29-03-2018 MC49_RS11825 3f99d5c6fad0ad97431090cabd788bad 597 PRINTS PR00315 GTP-binding elongation factor signature 126 135 4.0E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS11825 3f99d5c6fad0ad97431090cabd788bad 597 PRINTS PR00315 GTP-binding elongation factor signature 6 19 4.0E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS11825 3f99d5c6fad0ad97431090cabd788bad 597 PRINTS PR00315 GTP-binding elongation factor signature 90 101 4.0E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS11825 3f99d5c6fad0ad97431090cabd788bad 597 PRINTS PR00315 GTP-binding elongation factor signature 74 84 4.0E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS11825 3f99d5c6fad0ad97431090cabd788bad 597 PRINTS PR00315 GTP-binding elongation factor signature 49 57 4.0E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS11825 3f99d5c6fad0ad97431090cabd788bad 597 Pfam PF00679 Elongation factor G C-terminus 399 484 9.3E-20 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like MC49_RS11825 3f99d5c6fad0ad97431090cabd788bad 597 SUPERFAMILY SSF54980 399 493 2.25E-24 T 29-03-2018 IPR035647 EF-G domain III/V-like MC49_RS11825 3f99d5c6fad0ad97431090cabd788bad 597 Pfam PF00009 Elongation factor Tu GTP binding domain 3 181 5.9E-52 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS11825 3f99d5c6fad0ad97431090cabd788bad 597 TIGRFAM TIGR01393 lepA: elongation factor 4 3 594 7.5E-299 T 29-03-2018 IPR006297 Elongation factor 4 GO:0005525 MC49_RS11825 3f99d5c6fad0ad97431090cabd788bad 597 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 174 2.3E-17 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MC49_RS11825 3f99d5c6fad0ad97431090cabd788bad 597 Gene3D G3DSA:3.30.70.870 288 367 1.4E-27 T 29-03-2018 MC49_RS11825 3f99d5c6fad0ad97431090cabd788bad 597 Gene3D G3DSA:3.30.70.240 390 549 2.0E-25 T 29-03-2018 MC49_RS11825 3f99d5c6fad0ad97431090cabd788bad 597 Pfam PF03144 Elongation factor Tu domain 2 205 275 7.8E-12 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MC49_RS11825 3f99d5c6fad0ad97431090cabd788bad 597 SUPERFAMILY SSF52540 2 235 1.6E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS05930 0d060c7942d27e90030845266ceefc84 299 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 25 290 7.5E-105 T 29-03-2018 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 MC49_RS05930 0d060c7942d27e90030845266ceefc84 299 SUPERFAMILY SSF51730 22 294 6.08E-95 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like MC49_RS05930 0d060c7942d27e90030845266ceefc84 299 Pfam PF02219 Methylenetetrahydrofolate reductase 18 291 6.6E-104 T 29-03-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 MC49_RS05930 0d060c7942d27e90030845266ceefc84 299 Gene3D G3DSA:3.20.20.220 1 297 4.9E-97 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like MC49_RS15570 b52182699a6935cf25707dd4c1799797 528 Gene3D G3DSA:3.30.450.20 83 185 2.9E-11 T 29-03-2018 MC49_RS15570 b52182699a6935cf25707dd4c1799797 528 Gene3D G3DSA:1.10.8.60 393 451 1.5E-19 T 29-03-2018 MC49_RS15570 b52182699a6935cf25707dd4c1799797 528 SUPERFAMILY SSF52540 207 448 1.62E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS15570 b52182699a6935cf25707dd4c1799797 528 Gene3D G3DSA:3.40.50.300 186 392 1.3E-24 T 29-03-2018 MC49_RS15570 b52182699a6935cf25707dd4c1799797 528 TIGRFAM TIGR04381 HTH_TypR: TyrR family helix-turn-helix domain 467 514 5.7E-28 T 29-03-2018 IPR030828 TyrR family, helix-turn-helix domain GO:0003677 MC49_RS15570 b52182699a6935cf25707dd4c1799797 528 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 231 244 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MC49_RS15570 b52182699a6935cf25707dd4c1799797 528 SUPERFAMILY SSF46689 462 514 5.38E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS15570 b52182699a6935cf25707dd4c1799797 528 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 293 308 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MC49_RS15570 b52182699a6935cf25707dd4c1799797 528 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 420 429 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site MC49_RS15570 b52182699a6935cf25707dd4c1799797 528 Pfam PF00158 Sigma-54 interaction domain 208 373 4.3E-62 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MC49_RS15570 b52182699a6935cf25707dd4c1799797 528 Gene3D G3DSA:1.10.10.60 459 515 6.0E-6 T 29-03-2018 MC49_RS15570 b52182699a6935cf25707dd4c1799797 528 SUPERFAMILY SSF55785 80 164 1.69E-6 T 29-03-2018 IPR000014 PAS domain MC49_RS15570 b52182699a6935cf25707dd4c1799797 528 SUPERFAMILY SSF55021 2 75 6.11E-6 T 29-03-2018 MC49_RS15570 b52182699a6935cf25707dd4c1799797 528 Gene3D G3DSA:3.30.70.260 1 82 2.3E-9 T 29-03-2018 MC49_RS15570 b52182699a6935cf25707dd4c1799797 528 SMART SM00382 227 371 5.9E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS07860 9c1844515637acef7ce55e8642dd9448 311 Pfam PF00303 Thymidylate synthase 2 311 2.7E-72 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MC49_RS07860 9c1844515637acef7ce55e8642dd9448 311 Hamap MF_00008 Thymidylate synthase [thyA]. 1 311 31.495 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MC49_RS07860 9c1844515637acef7ce55e8642dd9448 311 ProSitePatterns PS00091 Thymidylate synthase active site. 168 196 - T 29-03-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MC49_RS07860 9c1844515637acef7ce55e8642dd9448 311 PRINTS PR00108 Thymidylate synthase family signature 239 256 9.9E-18 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MC49_RS07860 9c1844515637acef7ce55e8642dd9448 311 PRINTS PR00108 Thymidylate synthase family signature 183 198 9.9E-18 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MC49_RS07860 9c1844515637acef7ce55e8642dd9448 311 PRINTS PR00108 Thymidylate synthase family signature 201 227 9.9E-18 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MC49_RS07860 9c1844515637acef7ce55e8642dd9448 311 PRINTS PR00108 Thymidylate synthase family signature 44 65 9.9E-18 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MC49_RS07860 9c1844515637acef7ce55e8642dd9448 311 PRINTS PR00108 Thymidylate synthase family signature 157 176 9.9E-18 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MC49_RS07860 9c1844515637acef7ce55e8642dd9448 311 SUPERFAMILY SSF55831 2 311 3.79E-89 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MC49_RS07860 9c1844515637acef7ce55e8642dd9448 311 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 2 311 1.4E-41 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MC49_RS07860 9c1844515637acef7ce55e8642dd9448 311 Gene3D G3DSA:3.30.572.10 1 311 1.3E-78 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MC49_RS15990 49fd7c4d8c33a0a4d9a831e522a6ba61 512 Gene3D G3DSA:3.40.720.10 194 473 3.5E-19 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 MC49_RS15990 49fd7c4d8c33a0a4d9a831e522a6ba61 512 SUPERFAMILY SSF53649 206 469 5.89E-14 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MC49_RS15990 49fd7c4d8c33a0a4d9a831e522a6ba61 512 Pfam PF00884 Sulfatase 205 468 2.6E-24 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 MC49_RS05185 fff48dd979632eda4b43292f041dd266 457 Pfam PF12804 MobA-like NTP transferase domain 8 120 6.0E-21 T 29-03-2018 IPR025877 MobA-like NTP transferase MC49_RS05185 fff48dd979632eda4b43292f041dd266 457 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 5 452 42.852 T 29-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 MC49_RS05185 fff48dd979632eda4b43292f041dd266 457 Gene3D G3DSA:2.160.10.10 323 440 3.0E-31 T 29-03-2018 MC49_RS05185 fff48dd979632eda4b43292f041dd266 457 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 403 431 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MC49_RS05185 fff48dd979632eda4b43292f041dd266 457 Gene3D G3DSA:2.160.10.10 245 322 5.6E-18 T 29-03-2018 MC49_RS05185 fff48dd979632eda4b43292f041dd266 457 SUPERFAMILY SSF51161 255 438 1.06E-50 T 29-03-2018 IPR011004 Trimeric LpxA-like MC49_RS05185 fff48dd979632eda4b43292f041dd266 457 Gene3D G3DSA:3.90.550.10 2 244 1.4E-48 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MC49_RS05185 fff48dd979632eda4b43292f041dd266 457 SUPERFAMILY SSF53448 7 252 5.22E-64 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MC49_RS05185 fff48dd979632eda4b43292f041dd266 457 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 267 299 2.2E-6 T 29-03-2018 IPR001451 Hexapeptide repeat MC49_RS05185 fff48dd979632eda4b43292f041dd266 457 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 395 429 3.8E-8 T 29-03-2018 IPR001451 Hexapeptide repeat MC49_RS05185 fff48dd979632eda4b43292f041dd266 457 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 7 454 3.2E-201 T 29-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 MC49_RS06405 b45b4c6ffaae8671adace803170f8065 142 ProSitePatterns PS00359 Ribosomal protein L11 signature. 127 142 - T 29-03-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS06405 b45b4c6ffaae8671adace803170f8065 142 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 3.1E-66 T 29-03-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS06405 b45b4c6ffaae8671adace803170f8065 142 Gene3D G3DSA:1.10.10.250 73 141 5.4E-25 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 MC49_RS06405 b45b4c6ffaae8671adace803170f8065 142 SMART SM00649 9 141 1.8E-85 T 29-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 MC49_RS06405 b45b4c6ffaae8671adace803170f8065 142 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 1.1E-29 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal MC49_RS06405 b45b4c6ffaae8671adace803170f8065 142 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 142 30.869 T 29-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 MC49_RS06405 b45b4c6ffaae8671adace803170f8065 142 SUPERFAMILY SSF54747 3 73 2.88E-30 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal MC49_RS06405 b45b4c6ffaae8671adace803170f8065 142 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 73 2.0E-15 T 29-03-2018 MC49_RS06405 b45b4c6ffaae8671adace803170f8065 142 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 140 5.1E-25 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 MC49_RS06405 b45b4c6ffaae8671adace803170f8065 142 Gene3D G3DSA:3.30.1550.10 3 72 1.2E-34 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal MC49_RS06405 b45b4c6ffaae8671adace803170f8065 142 SUPERFAMILY SSF46906 68 141 1.1E-26 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 MC49_RS01395 097447057f0c690f27a44966570a7f50 290 Gene3D G3DSA:3.30.950.10 122 237 1.2E-40 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MC49_RS01395 097447057f0c690f27a44966570a7f50 290 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 91 102 - T 29-03-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MC49_RS01395 097447057f0c690f27a44966570a7f50 290 Gene3D G3DSA:3.40.1010.10 11 121 2.2E-40 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MC49_RS01395 097447057f0c690f27a44966570a7f50 290 SUPERFAMILY SSF53790 13 232 7.72E-82 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MC49_RS01395 097447057f0c690f27a44966570a7f50 290 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 13 213 1.3E-23 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MC49_RS01395 097447057f0c690f27a44966570a7f50 290 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 14 283 1.8E-104 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MC49_RS01395 097447057f0c690f27a44966570a7f50 290 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 13 234 37.407 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MC49_RS01395 097447057f0c690f27a44966570a7f50 290 PIRSF PIRSF005917 2 287 1.5E-104 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MC49_RS19075 3725ff80148907e0ec9d6ef8b3f9e8b9 84 ProDom PD015223 IMMUNITY PLASMID BACTERIOCIN C COLICIN-E3 KLEBICIN 3D-STRUCTURE COLICIN CLOACIN IMME3 10 82 3.0E-17 T 29-03-2018 IPR003063 Cloacin immunity protein family GO:0015643|GO:0030153 MC49_RS19075 3725ff80148907e0ec9d6ef8b3f9e8b9 84 PRINTS PR01296 Cloacin immunity protein signature 19 39 3.0E-25 T 29-03-2018 IPR003063 Cloacin immunity protein family GO:0015643|GO:0030153 MC49_RS19075 3725ff80148907e0ec9d6ef8b3f9e8b9 84 PRINTS PR01296 Cloacin immunity protein signature 41 60 3.0E-25 T 29-03-2018 IPR003063 Cloacin immunity protein family GO:0015643|GO:0030153 MC49_RS19075 3725ff80148907e0ec9d6ef8b3f9e8b9 84 PRINTS PR01296 Cloacin immunity protein signature 2 18 3.0E-25 T 29-03-2018 IPR003063 Cloacin immunity protein family GO:0015643|GO:0030153 MC49_RS19075 3725ff80148907e0ec9d6ef8b3f9e8b9 84 PRINTS PR01296 Cloacin immunity protein signature 61 83 3.0E-25 T 29-03-2018 IPR003063 Cloacin immunity protein family GO:0015643|GO:0030153 MC49_RS19075 3725ff80148907e0ec9d6ef8b3f9e8b9 84 Gene3D G3DSA:3.10.50.20 3 82 7.4E-26 T 29-03-2018 MC49_RS19075 3725ff80148907e0ec9d6ef8b3f9e8b9 84 Pfam PF03513 Cloacin immunity protein 2 81 3.3E-32 T 29-03-2018 IPR003063 Cloacin immunity protein family GO:0015643|GO:0030153 MC49_RS19075 3725ff80148907e0ec9d6ef8b3f9e8b9 84 SUPERFAMILY SSF54552 2 84 4.71E-29 T 29-03-2018 IPR003063 Cloacin immunity protein family GO:0015643|GO:0030153 MC49_RS10055 7c5fed3882d214495befa926d6f3a6dd 72 SUPERFAMILY SSF52833 1 70 3.05E-18 T 29-03-2018 IPR012336 Thioredoxin-like fold MC49_RS10055 7c5fed3882d214495befa926d6f3a6dd 72 TIGRFAM TIGR02194 GlrX_NrdH: glutaredoxin-like protein NrdH 3 72 1.5E-31 T 29-03-2018 IPR011909 Glutaredoxin-like protein NrdH GO:0045454 MC49_RS10055 7c5fed3882d214495befa926d6f3a6dd 72 Gene3D G3DSA:3.40.30.10 1 72 2.1E-14 T 29-03-2018 MC49_RS10055 7c5fed3882d214495befa926d6f3a6dd 72 Pfam PF00462 Glutaredoxin 3 61 2.2E-14 T 29-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 MC49_RS18760 01439dfe75862345614fb0b68e32636e 416 ProSitePatterns PS00616 Histidine acid phosphatases phosphohistidine signature. 32 46 - T 29-03-2018 IPR033379 Histidine acid phosphatase active site MC49_RS18760 01439dfe75862345614fb0b68e32636e 416 ProSitePatterns PS00778 Histidine acid phosphatases active site signature. 307 323 - T 29-03-2018 IPR033379 Histidine acid phosphatase active site MC49_RS18760 01439dfe75862345614fb0b68e32636e 416 SUPERFAMILY SSF53254 28 413 2.69E-80 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MC49_RS18760 01439dfe75862345614fb0b68e32636e 416 Pfam PF00328 Histidine phosphatase superfamily (branch 2) 59 361 8.8E-16 T 29-03-2018 IPR000560 Histidine phosphatase superfamily, clade-2 GO:0003993 MC49_RS18760 01439dfe75862345614fb0b68e32636e 416 Gene3D G3DSA:3.40.50.1240 17 416 4.7E-49 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MC49_RS18365 ca17e7c50d7ebaea98f941124a819d2f 188 SUPERFAMILY SSF53041 3 145 1.07E-35 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MC49_RS18365 ca17e7c50d7ebaea98f941124a819d2f 188 ProSitePatterns PS00397 Site-specific recombinases active site. 7 15 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 MC49_RS18365 ca17e7c50d7ebaea98f941124a819d2f 188 ProSitePatterns PS00398 Site-specific recombinases signature 2. 63 75 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 MC49_RS18365 ca17e7c50d7ebaea98f941124a819d2f 188 Pfam PF00239 Resolvase, N terminal domain 5 144 7.9E-35 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MC49_RS18365 ca17e7c50d7ebaea98f941124a819d2f 188 SMART SM00857 4 145 3.8E-45 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MC49_RS18365 ca17e7c50d7ebaea98f941124a819d2f 188 Gene3D G3DSA:1.20.5.40 116 143 3.1E-12 T 29-03-2018 MC49_RS18365 ca17e7c50d7ebaea98f941124a819d2f 188 Gene3D G3DSA:1.10.10.60 145 188 3.4E-8 T 29-03-2018 MC49_RS18365 ca17e7c50d7ebaea98f941124a819d2f 188 Gene3D G3DSA:3.40.50.1390 1 115 1.4E-28 T 29-03-2018 MC49_RS12400 6a84bf8861ac24f2f87de61fc6830d33 70 Pfam PF00313 'Cold-shock' DNA-binding domain 5 69 1.0E-32 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MC49_RS12400 6a84bf8861ac24f2f87de61fc6830d33 70 PIRSF PIRSF002599 1 70 1.3E-25 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 MC49_RS12400 6a84bf8861ac24f2f87de61fc6830d33 70 SMART SM00357 6 70 6.0E-31 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 MC49_RS12400 6a84bf8861ac24f2f87de61fc6830d33 70 SUPERFAMILY SSF50249 4 69 2.79E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS12400 6a84bf8861ac24f2f87de61fc6830d33 70 ProSitePatterns PS00352 'Cold-shock' domain signature. 18 37 - T 29-03-2018 IPR019844 Cold-shock conserved site MC49_RS12400 6a84bf8861ac24f2f87de61fc6830d33 70 PRINTS PR00050 Cold shock protein signature 43 61 5.1E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MC49_RS12400 6a84bf8861ac24f2f87de61fc6830d33 70 PRINTS PR00050 Cold shock protein signature 7 22 5.1E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MC49_RS12400 6a84bf8861ac24f2f87de61fc6830d33 70 PRINTS PR00050 Cold shock protein signature 28 37 5.1E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MC49_RS12400 6a84bf8861ac24f2f87de61fc6830d33 70 Gene3D G3DSA:2.40.50.140 1 70 4.7E-29 T 29-03-2018 MC49_RS05145 ba4f11eb3a93ee1e9c6d9f8a971eeca9 274 Gene3D G3DSA:1.20.120.220 98 274 3.0E-53 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05145 ba4f11eb3a93ee1e9c6d9f8a971eeca9 274 Pfam PF00119 ATP synthase A chain 50 268 5.1E-55 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05145 ba4f11eb3a93ee1e9c6d9f8a971eeca9 274 SUPERFAMILY SSF81336 98 268 1.18E-48 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05145 ba4f11eb3a93ee1e9c6d9f8a971eeca9 274 ProSitePatterns PS00449 ATP synthase a subunit signature. 209 218 - T 29-03-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05145 ba4f11eb3a93ee1e9c6d9f8a971eeca9 274 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 41 269 6.8E-42 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05145 ba4f11eb3a93ee1e9c6d9f8a971eeca9 274 Hamap MF_01393 ATP synthase subunit a [atpB]. 11 274 15.637 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05145 ba4f11eb3a93ee1e9c6d9f8a971eeca9 274 PRINTS PR00123 ATP synthase A subunit signature 107 123 1.1E-14 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05145 ba4f11eb3a93ee1e9c6d9f8a971eeca9 274 PRINTS PR00123 ATP synthase A subunit signature 254 269 1.1E-14 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05145 ba4f11eb3a93ee1e9c6d9f8a971eeca9 274 PRINTS PR00123 ATP synthase A subunit signature 206 228 1.1E-14 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS14580 e5feaa704842e154f35f8182327a059a 238 Gene3D G3DSA:2.40.170.20 27 235 1.6E-19 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MC49_RS14580 e5feaa704842e154f35f8182327a059a 238 SUPERFAMILY SSF56935 28 231 3.66E-24 T 29-03-2018 MC49_RS14580 e5feaa704842e154f35f8182327a059a 238 Pfam PF00593 TonB dependent receptor 34 231 3.0E-14 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MC49_RS15760 1224f52b6adcbac7a2ecaf2944ec8330 221 Gene3D G3DSA:2.40.30.20 1 93 1.2E-27 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS15760 1224f52b6adcbac7a2ecaf2944ec8330 221 Gene3D G3DSA:2.40.30.20 102 207 2.1E-24 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS15760 1224f52b6adcbac7a2ecaf2944ec8330 221 PIRSF PIRSF000498 1 211 8.2E-73 T 29-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MC49_RS15760 1224f52b6adcbac7a2ecaf2944ec8330 221 SUPERFAMILY SSF63380 1 93 1.87E-28 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MC49_RS15760 1224f52b6adcbac7a2ecaf2944ec8330 221 Pfam PF00677 Lumazine binding domain 100 185 1.6E-20 T 29-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MC49_RS15760 1224f52b6adcbac7a2ecaf2944ec8330 221 Pfam PF00677 Lumazine binding domain 3 87 1.3E-21 T 29-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MC49_RS15760 1224f52b6adcbac7a2ecaf2944ec8330 221 SUPERFAMILY SSF63380 94 203 2.64E-30 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MC49_RS15760 1224f52b6adcbac7a2ecaf2944ec8330 221 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 205 1.3E-79 T 29-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MC49_RS10845 d4e427495899ed3f3e32fd40995adbb1 524 SUPERFAMILY SSF56176 435 522 2.13E-23 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 MC49_RS10845 d4e427495899ed3f3e32fd40995adbb1 524 Gene3D G3DSA:3.10.580.10 281 431 1.2E-24 T 29-03-2018 MC49_RS10845 d4e427495899ed3f3e32fd40995adbb1 524 Pfam PF03471 Transporter associated domain 440 514 4.3E-20 T 29-03-2018 IPR005170 Transporter-associated domain MC49_RS10845 d4e427495899ed3f3e32fd40995adbb1 524 SUPERFAMILY SSF54631 292 421 3.54E-23 T 29-03-2018 MC49_RS10845 d4e427495899ed3f3e32fd40995adbb1 524 Gene3D G3DSA:3.30.465.10 432 515 2.2E-22 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 MC49_RS10845 d4e427495899ed3f3e32fd40995adbb1 524 SMART SM01091 437 516 8.1E-26 T 29-03-2018 IPR005170 Transporter-associated domain MC49_RS10845 d4e427495899ed3f3e32fd40995adbb1 524 Pfam PF00571 CBS domain 371 420 9.9E-6 T 29-03-2018 IPR000644 CBS domain MC49_RS10845 d4e427495899ed3f3e32fd40995adbb1 524 Pfam PF00571 CBS domain 302 356 0.0047 T 29-03-2018 IPR000644 CBS domain MC49_RS10845 d4e427495899ed3f3e32fd40995adbb1 524 Pfam PF03741 Integral membrane protein TerC family 15 203 1.9E-51 T 29-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 MC49_RS06260 88ab5065d3c9ec2c4ef9bd3273af29e3 191 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 7.2E-14 T 29-03-2018 MC49_RS06260 88ab5065d3c9ec2c4ef9bd3273af29e3 191 PRINTS PR00096 Glutamine amidotransferase superfamily signature 168 181 7.2E-14 T 29-03-2018 MC49_RS06260 88ab5065d3c9ec2c4ef9bd3273af29e3 191 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 7.2E-14 T 29-03-2018 MC49_RS06260 88ab5065d3c9ec2c4ef9bd3273af29e3 191 PRINTS PR00097 Anthranilate synthase component II signature 168 181 2.0E-36 T 29-03-2018 MC49_RS06260 88ab5065d3c9ec2c4ef9bd3273af29e3 191 PRINTS PR00097 Anthranilate synthase component II signature 2 16 2.0E-36 T 29-03-2018 MC49_RS06260 88ab5065d3c9ec2c4ef9bd3273af29e3 191 PRINTS PR00097 Anthranilate synthase component II signature 47 56 2.0E-36 T 29-03-2018 MC49_RS06260 88ab5065d3c9ec2c4ef9bd3273af29e3 191 PRINTS PR00097 Anthranilate synthase component II signature 74 85 2.0E-36 T 29-03-2018 MC49_RS06260 88ab5065d3c9ec2c4ef9bd3273af29e3 191 PRINTS PR00097 Anthranilate synthase component II signature 119 131 2.0E-36 T 29-03-2018 MC49_RS06260 88ab5065d3c9ec2c4ef9bd3273af29e3 191 PRINTS PR00097 Anthranilate synthase component II signature 99 107 2.0E-36 T 29-03-2018 MC49_RS06260 88ab5065d3c9ec2c4ef9bd3273af29e3 191 Gene3D G3DSA:3.40.50.880 1 191 4.2E-58 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MC49_RS06260 88ab5065d3c9ec2c4ef9bd3273af29e3 191 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 190 4.7E-90 T 29-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MC49_RS06260 88ab5065d3c9ec2c4ef9bd3273af29e3 191 Pfam PF00117 Glutamine amidotransferase class-I 4 189 8.1E-57 T 29-03-2018 IPR017926 Glutamine amidotransferase MC49_RS06260 88ab5065d3c9ec2c4ef9bd3273af29e3 191 SUPERFAMILY SSF52317 1 190 2.95E-55 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MC49_RS06260 88ab5065d3c9ec2c4ef9bd3273af29e3 191 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 7.8E-6 T 29-03-2018 MC49_RS06260 88ab5065d3c9ec2c4ef9bd3273af29e3 191 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 7.8E-6 T 29-03-2018 MC49_RS05660 04557d7cb855528ab391e657d5cedc4c 266 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 202 230 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MC49_RS05660 04557d7cb855528ab391e657d5cedc4c 266 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 83 242 7.9E-75 T 29-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 MC49_RS05660 04557d7cb855528ab391e657d5cedc4c 266 Gene3D G3DSA:1.10.3130.10 1 133 1.6E-38 T 29-03-2018 MC49_RS05660 04557d7cb855528ab391e657d5cedc4c 266 SMART SM00971 9 113 1.4E-58 T 29-03-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 MC49_RS05660 04557d7cb855528ab391e657d5cedc4c 266 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 193 227 1.5E-9 T 29-03-2018 IPR001451 Hexapeptide repeat MC49_RS05660 04557d7cb855528ab391e657d5cedc4c 266 Gene3D G3DSA:2.160.10.10 134 260 4.7E-28 T 29-03-2018 MC49_RS05660 04557d7cb855528ab391e657d5cedc4c 266 Pfam PF06426 Serine acetyltransferase, N-terminal 9 113 3.8E-38 T 29-03-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 MC49_RS05660 04557d7cb855528ab391e657d5cedc4c 266 SUPERFAMILY SSF51161 9 260 2.22E-65 T 29-03-2018 IPR011004 Trimeric LpxA-like MC49_RS05660 04557d7cb855528ab391e657d5cedc4c 266 PIRSF PIRSF000441 75 261 1.5E-60 T 29-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 MC49_RS03410 7187bea4d035cdb9ce5ca81c40089f9f 282 Pfam PF00809 Pterin binding enzyme 18 257 6.2E-91 T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MC49_RS03410 7187bea4d035cdb9ce5ca81c40089f9f 282 Gene3D G3DSA:3.20.20.20 154 277 6.0E-51 T 29-03-2018 MC49_RS03410 7187bea4d035cdb9ce5ca81c40089f9f 282 Gene3D G3DSA:3.20.20.20 14 153 2.4E-61 T 29-03-2018 MC49_RS03410 7187bea4d035cdb9ce5ca81c40089f9f 282 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 51 64 - T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MC49_RS03410 7187bea4d035cdb9ce5ca81c40089f9f 282 SUPERFAMILY SSF51717 8 272 1.83E-107 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MC49_RS03410 7187bea4d035cdb9ce5ca81c40089f9f 282 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 17 32 - T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MC49_RS03410 7187bea4d035cdb9ce5ca81c40089f9f 282 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 16 271 9.4E-107 T 29-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 MC49_RS09090 8c351b9f5858bf96799bd65dccb461da 213 Gene3D G3DSA:3.30.70.20 6 28 0.006 T 29-03-2018 MC49_RS09090 8c351b9f5858bf96799bd65dccb461da 213 Gene3D G3DSA:3.30.70.20 93 130 5.3E-20 T 29-03-2018 MC49_RS09090 8c351b9f5858bf96799bd65dccb461da 213 Pfam PF12800 4Fe-4S binding domain 22 36 0.11 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MC49_RS09090 8c351b9f5858bf96799bd65dccb461da 213 SUPERFAMILY SSF54862 13 200 2.72E-63 T 29-03-2018 MC49_RS09090 8c351b9f5858bf96799bd65dccb461da 213 Gene3D G3DSA:3.30.70.20 131 178 5.4E-16 T 29-03-2018 MC49_RS09090 8c351b9f5858bf96799bd65dccb461da 213 Pfam PF13247 4Fe-4S dicluster domain 74 165 2.5E-25 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MC49_RS09090 8c351b9f5858bf96799bd65dccb461da 213 TIGRFAM TIGR02951 DMSO_dmsB: dimethylsulfoxide reductase, chain B 14 175 8.9E-77 T 29-03-2018 IPR014297 Dimethylsulphoxide reductase, chain B MC49_RS09090 8c351b9f5858bf96799bd65dccb461da 213 Gene3D G3DSA:3.30.70.20 29 92 1.8E-16 T 29-03-2018 MC49_RS09090 8c351b9f5858bf96799bd65dccb461da 213 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 111 122 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MC49_RS08935 0e8bc2b6121086590135cbe3274d325c 349 Gene3D G3DSA:2.40.50.140 287 338 4.3E-7 T 29-03-2018 MC49_RS08935 0e8bc2b6121086590135cbe3274d325c 349 Gene3D G3DSA:2.40.50.100 242 286 6.4E-5 T 29-03-2018 MC49_RS08935 0e8bc2b6121086590135cbe3274d325c 349 SUPERFAMILY SSF50331 240 346 6.07E-15 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal MC49_RS08935 0e8bc2b6121086590135cbe3274d325c 349 Pfam PF00005 ABC transporter 23 164 1.1E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS08935 0e8bc2b6121086590135cbe3274d325c 349 SUPERFAMILY SSF52540 7 246 1.33E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS08935 0e8bc2b6121086590135cbe3274d325c 349 Gene3D G3DSA:3.40.50.300 2 241 1.6E-76 T 29-03-2018 MC49_RS08935 0e8bc2b6121086590135cbe3274d325c 349 Pfam PF08402 TOBE domain 274 344 1.5E-9 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 MC49_RS08935 0e8bc2b6121086590135cbe3274d325c 349 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS08935 0e8bc2b6121086590135cbe3274d325c 349 SMART SM00382 31 214 4.7E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS08980 5ca46298cb7ff3c96d2cbac7435863d8 219 Pfam PF00484 Carbonic anhydrase 39 188 7.2E-51 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MC49_RS08980 5ca46298cb7ff3c96d2cbac7435863d8 219 SUPERFAMILY SSF53056 1 212 2.22E-76 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MC49_RS08980 5ca46298cb7ff3c96d2cbac7435863d8 219 Gene3D G3DSA:3.40.1050.10 1 218 1.3E-74 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MC49_RS08980 5ca46298cb7ff3c96d2cbac7435863d8 219 SMART SM00947 31 193 5.9E-67 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MC49_RS08980 5ca46298cb7ff3c96d2cbac7435863d8 219 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 83 103 - T 29-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MC49_RS08980 5ca46298cb7ff3c96d2cbac7435863d8 219 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 43 50 - T 29-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MC49_RS09025 aaf7eb3ea7c032c4b56e136b2bc3eba9 166 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 134 1.0E-42 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MC49_RS09025 aaf7eb3ea7c032c4b56e136b2bc3eba9 166 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 134 8.1E-36 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MC49_RS09025 aaf7eb3ea7c032c4b56e136b2bc3eba9 166 SUPERFAMILY SSF55083 1 156 1.83E-51 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MC49_RS09025 aaf7eb3ea7c032c4b56e136b2bc3eba9 166 Gene3D G3DSA:3.30.70.560 1 158 3.7E-53 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MC49_RS09025 aaf7eb3ea7c032c4b56e136b2bc3eba9 166 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 89 100 - T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MC49_RS06445 92d99efa50cb8f53dae8e15c8b58da1c 390 PIRSF PIRSF001434 1 390 2.1E-122 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MC49_RS06445 92d99efa50cb8f53dae8e15c8b58da1c 390 Gene3D G3DSA:3.40.640.10 2 253 6.1E-44 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS06445 92d99efa50cb8f53dae8e15c8b58da1c 390 Gene3D G3DSA:3.90.1150.10 255 390 3.4E-38 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS06445 92d99efa50cb8f53dae8e15c8b58da1c 390 SUPERFAMILY SSF53383 22 387 4.13E-95 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS06445 92d99efa50cb8f53dae8e15c8b58da1c 390 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 18 386 3.4E-113 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MC49_RS06445 92d99efa50cb8f53dae8e15c8b58da1c 390 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 196 210 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MC49_RS16900 da8aaa542af97ad28fcfa510b2267549 91 SUPERFAMILY SSF47413 4 79 8.58E-20 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS16900 da8aaa542af97ad28fcfa510b2267549 91 SMART SM00530 12 67 1.5E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS16900 da8aaa542af97ad28fcfa510b2267549 91 Pfam PF01381 Helix-turn-helix 13 67 7.1E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS16900 da8aaa542af97ad28fcfa510b2267549 91 Gene3D G3DSA:1.10.3100.10 2 87 6.5E-21 T 29-03-2018 IPR027910 YdiL-like domain MC49_RS04475 366ea6d4e6fef692a3f9c84408d9675d 479 Gene3D G3DSA:3.40.50.620 1 129 1.8E-27 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS04475 366ea6d4e6fef692a3f9c84408d9675d 479 SUPERFAMILY SSF52425 6 187 1.44E-46 T 29-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 MC49_RS04475 366ea6d4e6fef692a3f9c84408d9675d 479 Gene3D G3DSA:1.10.579.10 289 469 1.1E-72 T 29-03-2018 MC49_RS04475 366ea6d4e6fef692a3f9c84408d9675d 479 Pfam PF03441 FAD binding domain of DNA photolyase 271 465 4.8E-82 T 29-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 MC49_RS04475 366ea6d4e6fef692a3f9c84408d9675d 479 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 321 333 - T 29-03-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal MC49_RS04475 366ea6d4e6fef692a3f9c84408d9675d 479 SUPERFAMILY SSF48173 187 468 1.96E-106 T 29-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 MC49_RS04475 366ea6d4e6fef692a3f9c84408d9675d 479 Gene3D G3DSA:1.25.40.80 135 288 6.8E-37 T 29-03-2018 MC49_RS04475 366ea6d4e6fef692a3f9c84408d9675d 479 Pfam PF00875 DNA photolyase 7 171 2.4E-39 T 29-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 MC49_RS04475 366ea6d4e6fef692a3f9c84408d9675d 479 PRINTS PR00147 DNA photolyase signature 380 394 2.6E-27 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 MC49_RS04475 366ea6d4e6fef692a3f9c84408d9675d 479 PRINTS PR00147 DNA photolyase signature 146 162 2.6E-27 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 MC49_RS04475 366ea6d4e6fef692a3f9c84408d9675d 479 PRINTS PR00147 DNA photolyase signature 321 337 2.6E-27 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 MC49_RS04475 366ea6d4e6fef692a3f9c84408d9675d 479 PRINTS PR00147 DNA photolyase signature 341 359 2.6E-27 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 MC49_RS04475 366ea6d4e6fef692a3f9c84408d9675d 479 ProSitePatterns PS00691 DNA photolyases class 1 signature 2. 341 360 - T 29-03-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal MC49_RS03925 b6babb351b55540e347ebd17ab5e6882 274 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 9.8E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS03925 b6babb351b55540e347ebd17ab5e6882 274 Hamap MF_01233 HTH-type transcriptional regulator HdfR [hdfR]. 5 274 48.647 T 29-03-2018 IPR020890 Transcription regulator HTH, HdfR GO:0003677|GO:0003700|GO:0045892 MC49_RS03925 b6babb351b55540e347ebd17ab5e6882 274 SUPERFAMILY SSF53850 84 266 2.02E-14 T 29-03-2018 MC49_RS03925 b6babb351b55540e347ebd17ab5e6882 274 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 4.1E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS03925 b6babb351b55540e347ebd17ab5e6882 274 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 4.1E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS03925 b6babb351b55540e347ebd17ab5e6882 274 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 4.1E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS03925 b6babb351b55540e347ebd17ab5e6882 274 Pfam PF03466 LysR substrate binding domain 91 270 3.1E-12 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS03925 b6babb351b55540e347ebd17ab5e6882 274 SUPERFAMILY SSF46785 6 88 2.53E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS03925 b6babb351b55540e347ebd17ab5e6882 274 Gene3D G3DSA:1.10.10.10 3 87 1.2E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS03925 b6babb351b55540e347ebd17ab5e6882 274 Gene3D G3DSA:3.40.190.10 88 253 2.2E-12 T 29-03-2018 MC49_RS02475 ef4b7c4b90248a6d7819c7e5a6d3cf2e 415 Gene3D G3DSA:1.10.10.60 368 410 8.2E-13 T 29-03-2018 MC49_RS02475 ef4b7c4b90248a6d7819c7e5a6d3cf2e 415 Gene3D G3DSA:3.40.50.2300 2 152 2.3E-30 T 29-03-2018 MC49_RS02475 ef4b7c4b90248a6d7819c7e5a6d3cf2e 415 SUPERFAMILY SSF46689 355 409 7.17E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS02475 ef4b7c4b90248a6d7819c7e5a6d3cf2e 415 Pfam PF14532 Sigma-54 interaction domain 144 279 6.6E-18 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MC49_RS02475 ef4b7c4b90248a6d7819c7e5a6d3cf2e 415 Gene3D G3DSA:1.10.8.60 285 367 4.7E-16 T 29-03-2018 MC49_RS02475 ef4b7c4b90248a6d7819c7e5a6d3cf2e 415 Gene3D G3DSA:3.40.50.300 153 284 2.4E-11 T 29-03-2018 MC49_RS02475 ef4b7c4b90248a6d7819c7e5a6d3cf2e 415 Pfam PF00072 Response regulator receiver domain 8 115 2.0E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS02475 ef4b7c4b90248a6d7819c7e5a6d3cf2e 415 Pfam PF02954 Bacterial regulatory protein, Fis family 367 406 4.5E-8 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MC49_RS02475 ef4b7c4b90248a6d7819c7e5a6d3cf2e 415 SUPERFAMILY SSF52172 5 186 1.29E-36 T 29-03-2018 IPR011006 CheY-like superfamily MC49_RS02475 ef4b7c4b90248a6d7819c7e5a6d3cf2e 415 SUPERFAMILY SSF52540 142 341 3.14E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS02475 ef4b7c4b90248a6d7819c7e5a6d3cf2e 415 SMART SM00448 6 117 2.7E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS03565 9799f7261c7864567c76b5e322af4492 812 SMART SM00316 645 728 4.3E-13 T 29-03-2018 IPR022967 RNA-binding domain, S1 MC49_RS03565 9799f7261c7864567c76b5e322af4492 812 SUPERFAMILY SSF50249 72 151 4.56E-18 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS03565 9799f7261c7864567c76b5e322af4492 812 ProSitePatterns PS01175 Ribonuclease II family signature. 560 584 - T 29-03-2018 IPR022966 Ribonuclease II/R, conserved site MC49_RS03565 9799f7261c7864567c76b5e322af4492 812 Pfam PF08461 Ribonuclease R winged-helix domain 28 89 4.0E-15 T 29-03-2018 IPR013668 Ribonuclease R winged-helix domain MC49_RS03565 9799f7261c7864567c76b5e322af4492 812 SMART SM00955 265 593 7.2E-183 T 29-03-2018 MC49_RS03565 9799f7261c7864567c76b5e322af4492 812 TIGRFAM TIGR02063 RNase_R: ribonuclease R 24 728 3.6E-277 T 29-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 MC49_RS03565 9799f7261c7864567c76b5e322af4492 812 Gene3D G3DSA:2.40.50.140 644 729 1.8E-19 T 29-03-2018 MC49_RS03565 9799f7261c7864567c76b5e322af4492 812 Gene3D G3DSA:1.10.10.10 24 80 9.8E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS03565 9799f7261c7864567c76b5e322af4492 812 SUPERFAMILY SSF50249 228 644 3.26E-142 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS03565 9799f7261c7864567c76b5e322af4492 812 Pfam PF00575 S1 RNA binding domain 644 726 2.0E-15 T 29-03-2018 IPR003029 S1 domain GO:0003676 MC49_RS03565 9799f7261c7864567c76b5e322af4492 812 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 72 728 8.9E-270 T 29-03-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 MC49_RS03565 9799f7261c7864567c76b5e322af4492 812 SUPERFAMILY SSF50249 645 744 1.77E-22 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS03565 9799f7261c7864567c76b5e322af4492 812 Pfam PF08206 Ribonuclease B OB domain 92 149 3.4E-22 T 29-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain MC49_RS03565 9799f7261c7864567c76b5e322af4492 812 SMART SM00357 91 150 1.1E-13 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 MC49_RS03565 9799f7261c7864567c76b5e322af4492 812 Pfam PF00773 RNB domain 265 592 3.8E-109 T 29-03-2018 MC49_RS03565 9799f7261c7864567c76b5e322af4492 812 SUPERFAMILY SSF50249 143 241 7.03E-15 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS03565 9799f7261c7864567c76b5e322af4492 812 Hamap MF_01895 Ribonuclease R [rnr]. 43 728 56.897 T 29-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 MC49_RS03565 9799f7261c7864567c76b5e322af4492 812 Gene3D G3DSA:2.40.50.140 81 217 0.17 T 29-03-2018 MC49_RS11250 c6f70be438bed76eb997153c366ba429 336 SUPERFAMILY SSF51395 1 334 1.36E-103 T 29-03-2018 MC49_RS11250 c6f70be438bed76eb997153c366ba429 336 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 3 334 1.6E-154 T 29-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 MC49_RS11250 c6f70be438bed76eb997153c366ba429 336 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 80 99 - T 29-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 MC49_RS11250 c6f70be438bed76eb997153c366ba429 336 PIRSF PIRSF000164 13 336 3.1E-98 T 29-03-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 MC49_RS11250 c6f70be438bed76eb997153c366ba429 336 Gene3D G3DSA:3.20.20.70 1 336 4.9E-78 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS11250 c6f70be438bed76eb997153c366ba429 336 Pfam PF01180 Dihydroorotate dehydrogenase 47 334 5.0E-89 T 29-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 MC49_RS11250 c6f70be438bed76eb997153c366ba429 336 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 292 312 - T 29-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 MC49_RS11250 c6f70be438bed76eb997153c366ba429 336 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 2 336 51.083 T 29-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 MC49_RS11835 99ababdf3f37dacb71376c2b9a8ddce3 226 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 9 220 3.3E-73 T 29-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 MC49_RS11835 99ababdf3f37dacb71376c2b9a8ddce3 226 SUPERFAMILY SSF69065 5 159 2.27E-49 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 MC49_RS11835 99ababdf3f37dacb71376c2b9a8ddce3 226 Hamap MF_00104 Ribonuclease 3 [rnc]. 9 220 29.577 T 29-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 MC49_RS11835 99ababdf3f37dacb71376c2b9a8ddce3 226 Pfam PF14622 Ribonuclease-III-like 20 140 1.0E-33 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 MC49_RS11835 99ababdf3f37dacb71376c2b9a8ddce3 226 SMART SM00535 21 149 5.6E-56 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 MC49_RS11835 99ababdf3f37dacb71376c2b9a8ddce3 226 ProSitePatterns PS00517 Ribonuclease III family signature. 38 46 - T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 MC49_RS11835 99ababdf3f37dacb71376c2b9a8ddce3 226 SMART SM00358 156 224 1.1E-22 T 29-03-2018 IPR014720 Double-stranded RNA-binding domain MC49_RS11835 99ababdf3f37dacb71376c2b9a8ddce3 226 SUPERFAMILY SSF54768 109 223 4.09E-27 T 29-03-2018 MC49_RS11835 99ababdf3f37dacb71376c2b9a8ddce3 226 Gene3D G3DSA:3.30.160.20 147 220 1.4E-20 T 29-03-2018 MC49_RS11835 99ababdf3f37dacb71376c2b9a8ddce3 226 Pfam PF00035 Double-stranded RNA binding motif 156 220 1.1E-14 T 29-03-2018 IPR014720 Double-stranded RNA-binding domain MC49_RS11835 99ababdf3f37dacb71376c2b9a8ddce3 226 Gene3D G3DSA:1.10.1520.10 5 146 1.7E-44 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 MC49_RS18605 59c11cbb840d4c1b19803cce47d42fc9 903 Pfam PF01043 SecA preprotein cross-linking domain 232 358 1.5E-37 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 MC49_RS18605 59c11cbb840d4c1b19803cce47d42fc9 903 SUPERFAMILY SSF52540 368 415 2.82E-84 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS18605 59c11cbb840d4c1b19803cce47d42fc9 903 SUPERFAMILY SSF52540 5 228 2.82E-84 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS18605 59c11cbb840d4c1b19803cce47d42fc9 903 Gene3D G3DSA:3.40.50.300 417 634 1.8E-54 T 29-03-2018 MC49_RS18605 59c11cbb840d4c1b19803cce47d42fc9 903 Hamap MF_01382 Protein translocase subunit SecA [secA]. 5 832 19.813 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MC49_RS18605 59c11cbb840d4c1b19803cce47d42fc9 903 PRINTS PR00906 SecA protein signature 101 115 1.5E-73 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MC49_RS18605 59c11cbb840d4c1b19803cce47d42fc9 903 PRINTS PR00906 SecA protein signature 376 393 1.5E-73 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MC49_RS18605 59c11cbb840d4c1b19803cce47d42fc9 903 PRINTS PR00906 SecA protein signature 117 127 1.5E-73 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MC49_RS18605 59c11cbb840d4c1b19803cce47d42fc9 903 PRINTS PR00906 SecA protein signature 170 190 1.5E-73 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MC49_RS18605 59c11cbb840d4c1b19803cce47d42fc9 903 PRINTS PR00906 SecA protein signature 339 361 1.5E-73 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MC49_RS18605 59c11cbb840d4c1b19803cce47d42fc9 903 PRINTS PR00906 SecA protein signature 413 426 1.5E-73 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MC49_RS18605 59c11cbb840d4c1b19803cce47d42fc9 903 PRINTS PR00906 SecA protein signature 63 87 1.5E-73 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MC49_RS18605 59c11cbb840d4c1b19803cce47d42fc9 903 Gene3D G3DSA:3.10.450.50 734 903 1.9E-55 T 29-03-2018 MC49_RS18605 59c11cbb840d4c1b19803cce47d42fc9 903 SUPERFAMILY SSF81767 227 368 3.4E-43 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 MC49_RS18605 59c11cbb840d4c1b19803cce47d42fc9 903 SMART SM00958 228 358 1.2E-80 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 MC49_RS18605 59c11cbb840d4c1b19803cce47d42fc9 903 SUPERFAMILY SSF81886 620 840 1.31E-85 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 MC49_RS18605 59c11cbb840d4c1b19803cce47d42fc9 903 SUPERFAMILY SSF81886 879 891 1.31E-85 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 MC49_RS18605 59c11cbb840d4c1b19803cce47d42fc9 903 Gene3D G3DSA:3.40.50.300 9 267 5.2E-59 T 29-03-2018 MC49_RS18605 59c11cbb840d4c1b19803cce47d42fc9 903 Gene3D G3DSA:3.40.50.300 301 416 9.1E-8 T 29-03-2018 MC49_RS18605 59c11cbb840d4c1b19803cce47d42fc9 903 Gene3D G3DSA:1.10.3060.10 635 733 8.2E-30 T 29-03-2018 MC49_RS18605 59c11cbb840d4c1b19803cce47d42fc9 903 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 28 816 0.0 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MC49_RS18605 59c11cbb840d4c1b19803cce47d42fc9 903 SUPERFAMILY SSF52540 416 618 4.75E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS18605 59c11cbb840d4c1b19803cce47d42fc9 903 Pfam PF07517 SecA DEAD-like domain 7 402 3.1E-132 T 29-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 MC49_RS18605 59c11cbb840d4c1b19803cce47d42fc9 903 SMART SM00957 6 402 0.0 T 29-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 MC49_RS18605 59c11cbb840d4c1b19803cce47d42fc9 903 ProSitePatterns PS01312 SecA family signature. 500 515 - T 29-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 MC49_RS18605 59c11cbb840d4c1b19803cce47d42fc9 903 Pfam PF07516 SecA Wing and Scaffold domain 617 830 3.2E-69 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 MC49_RS18605 59c11cbb840d4c1b19803cce47d42fc9 903 Pfam PF02810 SEC-C motif 883 900 6.4E-11 T 29-03-2018 IPR004027 SEC-C motif MC49_RS14045 efee7ace44abc05184d80abdbada8040 150 PRINTS PR01404 DATP pyrophosphohydrolase signature 99 120 2.8E-36 T 29-03-2018 IPR003564 Dihydroneopterin triphosphate diphosphatase GO:0008828|GO:0019177|GO:0046656 KEGG: 00790+3.6.1.67|MetaCyc: PWY-6147 MC49_RS14045 efee7ace44abc05184d80abdbada8040 150 PRINTS PR01404 DATP pyrophosphohydrolase signature 126 139 2.8E-36 T 29-03-2018 IPR003564 Dihydroneopterin triphosphate diphosphatase GO:0008828|GO:0019177|GO:0046656 KEGG: 00790+3.6.1.67|MetaCyc: PWY-6147 MC49_RS14045 efee7ace44abc05184d80abdbada8040 150 PRINTS PR01404 DATP pyrophosphohydrolase signature 71 90 2.8E-36 T 29-03-2018 IPR003564 Dihydroneopterin triphosphate diphosphatase GO:0008828|GO:0019177|GO:0046656 KEGG: 00790+3.6.1.67|MetaCyc: PWY-6147 MC49_RS14045 efee7ace44abc05184d80abdbada8040 150 PRINTS PR01404 DATP pyrophosphohydrolase signature 3 20 2.8E-36 T 29-03-2018 IPR003564 Dihydroneopterin triphosphate diphosphatase GO:0008828|GO:0019177|GO:0046656 KEGG: 00790+3.6.1.67|MetaCyc: PWY-6147 MC49_RS14045 efee7ace44abc05184d80abdbada8040 150 PRINTS PR01404 DATP pyrophosphohydrolase signature 20 41 2.8E-36 T 29-03-2018 IPR003564 Dihydroneopterin triphosphate diphosphatase GO:0008828|GO:0019177|GO:0046656 KEGG: 00790+3.6.1.67|MetaCyc: PWY-6147 MC49_RS14045 efee7ace44abc05184d80abdbada8040 150 PRINTS PR00502 NUDIX hydrolase family signature 33 47 5.2E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MC49_RS14045 efee7ace44abc05184d80abdbada8040 150 PRINTS PR00502 NUDIX hydrolase family signature 47 62 5.2E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MC49_RS14045 efee7ace44abc05184d80abdbada8040 150 Pfam PF00293 NUDIX domain 5 142 3.2E-21 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MC49_RS14045 efee7ace44abc05184d80abdbada8040 150 SUPERFAMILY SSF55811 3 143 5.42E-27 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MC49_RS14045 efee7ace44abc05184d80abdbada8040 150 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MC49_RS14045 efee7ace44abc05184d80abdbada8040 150 Gene3D G3DSA:3.90.79.10 1 147 2.3E-31 T 29-03-2018 MC49_RS17115 75c01df1e10263dfedde74b2a3243bb2 56 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 54 16.934 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS17115 75c01df1e10263dfedde74b2a3243bb2 56 Pfam PF01783 Ribosomal L32p protein family 2 56 1.9E-19 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS17115 75c01df1e10263dfedde74b2a3243bb2 56 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 55 2.2E-19 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS17115 75c01df1e10263dfedde74b2a3243bb2 56 SUPERFAMILY SSF57829 2 55 1.53E-18 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 MC49_RS17220 979a7613c036aca2d6d04938406dba5b 280 SMART SM00518 3 279 4.8E-131 T 29-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 MC49_RS17220 979a7613c036aca2d6d04938406dba5b 280 Pfam PF01261 Xylose isomerase-like TIM barrel 20 239 4.0E-41 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MC49_RS17220 979a7613c036aca2d6d04938406dba5b 280 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 215 231 - T 29-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 MC49_RS17220 979a7613c036aca2d6d04938406dba5b 280 Gene3D G3DSA:3.20.20.150 1 280 1.9E-61 T 29-03-2018 MC49_RS17220 979a7613c036aca2d6d04938406dba5b 280 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 69 77 - T 29-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 MC49_RS17220 979a7613c036aca2d6d04938406dba5b 280 Hamap MF_00152 Probable endonuclease 4 [nfo]. 2 279 43.555 T 29-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 MC49_RS17220 979a7613c036aca2d6d04938406dba5b 280 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 175 182 - T 29-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 MC49_RS17220 979a7613c036aca2d6d04938406dba5b 280 SUPERFAMILY SSF51658 1 278 1.57E-101 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MC49_RS17220 979a7613c036aca2d6d04938406dba5b 280 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 3 276 3.0E-108 T 29-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 MC49_RS08810 a182f65131b9fdebb876d5fe06218927 292 SUPERFAMILY SSF56176 6 171 1.85E-47 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 MC49_RS08810 a182f65131b9fdebb876d5fe06218927 292 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 183 282 1.6E-26 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal MC49_RS08810 a182f65131b9fdebb876d5fe06218927 292 Gene3D G3DSA:3.30.43.10 3 56 4.9E-13 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 MC49_RS08810 a182f65131b9fdebb876d5fe06218927 292 Gene3D G3DSA:3.30.390.50 178 292 6.9E-28 T 29-03-2018 MC49_RS08810 a182f65131b9fdebb876d5fe06218927 292 SMART SM01092 182 283 1.4E-25 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal MC49_RS08810 a182f65131b9fdebb876d5fe06218927 292 Gene3D G3DSA:3.30.465.10 57 173 2.0E-29 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 MC49_RS08810 a182f65131b9fdebb876d5fe06218927 292 SUPERFAMILY SSF55447 181 286 1.1E-26 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal MC49_RS08810 a182f65131b9fdebb876d5fe06218927 292 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 4 170 9.8E-47 T 29-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 MC49_RS16830 0115b100040722a8b8d885953f85032c 224 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 2.1E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS16830 0115b100040722a8b8d885953f85032c 224 Gene3D G3DSA:1.10.10.60 2 54 3.0E-13 T 29-03-2018 MC49_RS16830 0115b100040722a8b8d885953f85032c 224 Pfam PF09209 Domain of unknown function (DUF1956) 106 212 1.7E-14 T 29-03-2018 IPR015292 Transcription regulator YbiH, C-terminal MC49_RS16830 0115b100040722a8b8d885953f85032c 224 SUPERFAMILY SSF46689 8 78 2.31E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS16830 0115b100040722a8b8d885953f85032c 224 Gene3D G3DSA:1.10.357.10 55 220 7.3E-23 T 29-03-2018 MC49_RS16830 0115b100040722a8b8d885953f85032c 224 SUPERFAMILY SSF48498 100 214 2.8E-14 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MC49_RS08355 c7faedc2383a106b7dbba3f5c4c18da7 353 Gene3D G3DSA:3.40.50.10210 72 328 4.1E-90 T 29-03-2018 MC49_RS08355 c7faedc2383a106b7dbba3f5c4c18da7 353 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 15 339 2.8E-109 T 29-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 MC49_RS08355 c7faedc2383a106b7dbba3f5c4c18da7 353 Pfam PF02277 Phosphoribosyltransferase 11 339 1.8E-113 T 29-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 MC49_RS08355 c7faedc2383a106b7dbba3f5c4c18da7 353 Gene3D G3DSA:1.10.1610.10 5 71 1.6E-28 T 29-03-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 MC49_RS08355 c7faedc2383a106b7dbba3f5c4c18da7 353 SUPERFAMILY SSF52733 5 344 4.58E-105 T 29-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 MC49_RS18820 b3be93edfd0ecf2f55a75fc1164aa6a4 337 Gene3D G3DSA:3.40.50.2300 63 171 6.4E-22 T 29-03-2018 MC49_RS18820 b3be93edfd0ecf2f55a75fc1164aa6a4 337 Pfam PF13377 Periplasmic binding protein-like domain 174 334 2.9E-37 T 29-03-2018 MC49_RS18820 b3be93edfd0ecf2f55a75fc1164aa6a4 337 ProSitePatterns PS00356 LacI-type HTH domain signature. 9 27 - T 29-03-2018 MC49_RS18820 b3be93edfd0ecf2f55a75fc1164aa6a4 337 Gene3D G3DSA:1.10.260.40 21 62 3.7E-22 T 29-03-2018 MC49_RS18820 b3be93edfd0ecf2f55a75fc1164aa6a4 337 SUPERFAMILY SSF53822 66 335 2.75E-78 T 29-03-2018 IPR028082 Periplasmic binding protein-like I MC49_RS18820 b3be93edfd0ecf2f55a75fc1164aa6a4 337 Gene3D G3DSA:1.10.10.60 3 20 0.0017 T 29-03-2018 MC49_RS18820 b3be93edfd0ecf2f55a75fc1164aa6a4 337 Gene3D G3DSA:3.40.50.2300 172 337 2.7E-48 T 29-03-2018 MC49_RS18820 b3be93edfd0ecf2f55a75fc1164aa6a4 337 SMART SM00354 6 76 1.1E-28 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MC49_RS18820 b3be93edfd0ecf2f55a75fc1164aa6a4 337 SUPERFAMILY SSF47413 6 64 6.57E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS18820 b3be93edfd0ecf2f55a75fc1164aa6a4 337 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 8 18 8.3E-7 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MC49_RS18820 b3be93edfd0ecf2f55a75fc1164aa6a4 337 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 18 28 8.3E-7 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MC49_RS18820 b3be93edfd0ecf2f55a75fc1164aa6a4 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 53 1.2E-18 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MC49_RS06425 092341ed767ca1601a20752505d8889e 1342 Gene3D G3DSA:3.90.1100.10 646 713 1.9E-14 T 29-03-2018 MC49_RS06425 092341ed767ca1601a20752505d8889e 1342 Gene3D G3DSA:3.90.1100.10 432 645 8.1E-78 T 29-03-2018 MC49_RS06425 092341ed767ca1601a20752505d8889e 1342 Pfam PF04565 RNA polymerase Rpb2, domain 3 513 580 1.5E-30 T 29-03-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS06425 092341ed767ca1601a20752505d8889e 1342 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 13 1342 12.249 T 29-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS06425 092341ed767ca1601a20752505d8889e 1342 Pfam PF04560 RNA polymerase Rpb2, domain 7 1266 1340 1.8E-27 T 29-03-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS06425 092341ed767ca1601a20752505d8889e 1342 Pfam PF10385 RNA polymerase beta subunit external 1 domain 591 656 3.2E-24 T 29-03-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS06425 092341ed767ca1601a20752505d8889e 1342 Pfam PF04563 RNA polymerase beta subunit 26 500 3.8E-54 T 29-03-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS06425 092341ed767ca1601a20752505d8889e 1342 Gene3D G3DSA:2.40.270.10 1019 1242 1.8E-79 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS06425 092341ed767ca1601a20752505d8889e 1342 Pfam PF00562 RNA polymerase Rpb2, domain 6 717 1264 1.6E-159 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS06425 092341ed767ca1601a20752505d8889e 1342 ProSitePatterns PS00018 EF-hand calcium-binding domain. 413 425 - T 29-03-2018 IPR018247 EF-Hand 1, calcium-binding site MC49_RS06425 092341ed767ca1601a20752505d8889e 1342 SUPERFAMILY SSF64484 343 939 0.0 T 29-03-2018 MC49_RS06425 092341ed767ca1601a20752505d8889e 1342 SUPERFAMILY SSF64484 11 226 0.0 T 29-03-2018 MC49_RS06425 092341ed767ca1601a20752505d8889e 1342 SUPERFAMILY SSF64484 1039 1341 0.0 T 29-03-2018 MC49_RS06425 092341ed767ca1601a20752505d8889e 1342 Gene3D G3DSA:2.40.50.100 715 795 7.1E-28 T 29-03-2018 MC49_RS06425 092341ed767ca1601a20752505d8889e 1342 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1063 1075 - T 29-03-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS06425 092341ed767ca1601a20752505d8889e 1342 Pfam PF04561 RNA polymerase Rpb2, domain 2 336 454 7.2E-18 T 29-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS06425 092341ed767ca1601a20752505d8889e 1342 Pfam PF04561 RNA polymerase Rpb2, domain 2 151 223 3.0E-8 T 29-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS06425 092341ed767ca1601a20752505d8889e 1342 Gene3D G3DSA:2.40.50.150 814 949 1.8E-29 T 29-03-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS06425 092341ed767ca1601a20752505d8889e 1342 Gene3D G3DSA:3.90.1110.10 148 431 1.1E-66 T 29-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS06425 092341ed767ca1601a20752505d8889e 1342 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 8 1339 0.0 T 29-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS06425 092341ed767ca1601a20752505d8889e 1342 Gene3D G3DSA:3.90.1800.10 1267 1326 6.7E-12 T 29-03-2018 MC49_RS08720 cba937ee16986699b2be1611d904967e 452 Pfam PF01566 Natural resistance-associated macrophage protein 49 420 2.1E-117 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 MC49_RS08720 cba937ee16986699b2be1611d904967e 452 PRINTS PR00447 Natural resistance-associated macrophage protein signature 356 373 6.5E-56 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 MC49_RS08720 cba937ee16986699b2be1611d904967e 452 PRINTS PR00447 Natural resistance-associated macrophage protein signature 328 347 6.5E-56 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 MC49_RS08720 cba937ee16986699b2be1611d904967e 452 PRINTS PR00447 Natural resistance-associated macrophage protein signature 136 155 6.5E-56 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 MC49_RS08720 cba937ee16986699b2be1611d904967e 452 PRINTS PR00447 Natural resistance-associated macrophage protein signature 108 134 6.5E-56 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 MC49_RS08720 cba937ee16986699b2be1611d904967e 452 PRINTS PR00447 Natural resistance-associated macrophage protein signature 218 241 6.5E-56 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 MC49_RS08720 cba937ee16986699b2be1611d904967e 452 PRINTS PR00447 Natural resistance-associated macrophage protein signature 390 409 6.5E-56 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 MC49_RS08720 cba937ee16986699b2be1611d904967e 452 Hamap MF_00221 Divalent metal cation transporter MntH [mntH]. 20 446 35.842 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 MC49_RS08720 cba937ee16986699b2be1611d904967e 452 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 27 414 1.2E-110 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 MC49_RS11680 9244de40f66a27a0b779692372013a4a 160 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 14 138 6.0E-64 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 MC49_RS11680 9244de40f66a27a0b779692372013a4a 160 Hamap MF_00023 SsrA-binding protein [smpB]. 1 160 71.483 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 MC49_RS11680 9244de40f66a27a0b779692372013a4a 160 Gene3D G3DSA:2.40.280.10 14 133 8.7E-45 T 29-03-2018 IPR023620 Small protein B MC49_RS11680 9244de40f66a27a0b779692372013a4a 160 TIGRFAM TIGR00086 smpB: SsrA-binding protein 14 156 1.2E-52 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 MC49_RS11680 9244de40f66a27a0b779692372013a4a 160 SUPERFAMILY SSF74982 8 138 1.7E-49 T 29-03-2018 IPR023620 Small protein B MC49_RS11680 9244de40f66a27a0b779692372013a4a 160 ProSitePatterns PS01317 SsrA-binding protein. 32 44 - T 29-03-2018 IPR020081 SsrA-binding protein, conserved site MC49_RS11680 9244de40f66a27a0b779692372013a4a 160 Pfam PF01668 SmpB protein 14 157 7.4E-56 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 MC49_RS04030 45bdd9067ff4b7998e87c762e612ff07 128 Pfam PF01196 Ribosomal protein L17 20 116 9.2E-35 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS04030 45bdd9067ff4b7998e87c762e612ff07 128 Gene3D G3DSA:3.90.1030.10 1 117 4.1E-50 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS04030 45bdd9067ff4b7998e87c762e612ff07 128 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS04030 45bdd9067ff4b7998e87c762e612ff07 128 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 27.014 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS04030 45bdd9067ff4b7998e87c762e612ff07 128 SUPERFAMILY SSF64263 1 118 4.71E-51 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS04030 45bdd9067ff4b7998e87c762e612ff07 128 TIGRFAM TIGR00059 L17: ribosomal protein bL17 7 117 2.8E-51 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS13600 a2a34b091396d5b580248579fad881ca 240 SMART SM00327 33 214 0.0012 T 29-03-2018 IPR002035 von Willebrand factor, type A MC49_RS13600 a2a34b091396d5b580248579fad881ca 240 Pfam PF05762 VWA domain containing CoxE-like protein 30 162 1.6E-6 T 29-03-2018 IPR008912 Uncharacterised protein family CoxE-like MC49_RS13600 a2a34b091396d5b580248579fad881ca 240 Gene3D G3DSA:3.40.50.410 21 233 1.4E-13 T 29-03-2018 IPR002035 von Willebrand factor, type A MC49_RS13600 a2a34b091396d5b580248579fad881ca 240 SUPERFAMILY SSF53300 33 164 1.04E-12 T 29-03-2018 IPR002035 von Willebrand factor, type A MC49_RS12110 886450a34cf26355487dd0f815e81eaf 404 SUPERFAMILY SSF53383 5 390 1.26E-115 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS12110 886450a34cf26355487dd0f815e81eaf 404 Hamap MF_00331 Cysteine desulfurase IscS [iscS]. 1 395 55.221 T 29-03-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 MC49_RS12110 886450a34cf26355487dd0f815e81eaf 404 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 197 216 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site MC49_RS12110 886450a34cf26355487dd0f815e81eaf 404 Pfam PF00266 Aminotransferase class-V 5 368 1.1E-87 T 29-03-2018 IPR000192 Aminotransferase class V domain MC49_RS12110 886450a34cf26355487dd0f815e81eaf 404 TIGRFAM TIGR02006 IscS: cysteine desulfurase IscS 1 404 4.0E-231 T 29-03-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 MC49_RS12110 886450a34cf26355487dd0f815e81eaf 404 Gene3D G3DSA:3.40.640.10 1 236 8.4E-53 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS12110 886450a34cf26355487dd0f815e81eaf 404 Gene3D G3DSA:3.90.1150.10 237 404 1.8E-52 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS12110 886450a34cf26355487dd0f815e81eaf 404 PIRSF PIRSF005572 2 384 1.1E-139 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 MC49_RS08995 04fcad53e8d082bdedf44745ac3d9cdd 484 Pfam PF13583 Metallo-peptidase family M12B Reprolysin-like 170 232 5.0E-6 T 29-03-2018 MC49_RS08995 04fcad53e8d082bdedf44745ac3d9cdd 484 PIRSF PIRSF001205 2 484 1.4E-187 T 29-03-2018 IPR016294 Peptidase M10B GO:0004222|GO:0005509|GO:0005615|GO:0006508|GO:0008270 MC49_RS08995 04fcad53e8d082bdedf44745ac3d9cdd 484 SUPERFAMILY SSF51120 262 481 7.19E-41 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MC49_RS08995 04fcad53e8d082bdedf44745ac3d9cdd 484 PRINTS PR00313 NodO calcium binding signature 342 353 3.2E-11 T 29-03-2018 MC49_RS08995 04fcad53e8d082bdedf44745ac3d9cdd 484 PRINTS PR00313 NodO calcium binding signature 363 371 3.2E-11 T 29-03-2018 MC49_RS08995 04fcad53e8d082bdedf44745ac3d9cdd 484 PRINTS PR00313 NodO calcium binding signature 372 380 3.2E-11 T 29-03-2018 MC49_RS08995 04fcad53e8d082bdedf44745ac3d9cdd 484 PRINTS PR00313 NodO calcium binding signature 381 390 3.2E-11 T 29-03-2018 MC49_RS08995 04fcad53e8d082bdedf44745ac3d9cdd 484 Gene3D G3DSA:3.40.390.10 25 254 1.6E-37 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 MC49_RS08995 04fcad53e8d082bdedf44745ac3d9cdd 484 SMART SM00235 67 244 5.3E-23 T 29-03-2018 IPR006026 Peptidase, metallopeptidase GO:0006508|GO:0008237|GO:0008270 MC49_RS08995 04fcad53e8d082bdedf44745ac3d9cdd 484 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 368 386 - T 29-03-2018 IPR018511 Hemolysin-type calcium-binding conserved site MC49_RS08995 04fcad53e8d082bdedf44745ac3d9cdd 484 SUPERFAMILY SSF55486 11 258 2.84E-63 T 29-03-2018 MC49_RS08995 04fcad53e8d082bdedf44745ac3d9cdd 484 Gene3D G3DSA:2.150.10.10 255 484 5.7E-53 T 29-03-2018 MC49_RS08995 04fcad53e8d082bdedf44745ac3d9cdd 484 Pfam PF08548 Peptidase M10 serralysin C terminal 260 484 1.1E-78 T 29-03-2018 IPR013858 Peptidase M10 serralysin, C-terminal GO:0005509|GO:0005615 MC49_RS10570 9f1083e49249b9039a44bce5a5287838 434 Gene3D G3DSA:3.90.1150.10 8 180 4.9E-47 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS10570 9f1083e49249b9039a44bce5a5287838 434 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 12 431 49.547 T 29-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 MC49_RS10570 9f1083e49249b9039a44bce5a5287838 434 SUPERFAMILY SSF53383 14 431 3.69E-138 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS10570 9f1083e49249b9039a44bce5a5287838 434 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 24 431 5.7E-183 T 29-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 MC49_RS10570 9f1083e49249b9039a44bce5a5287838 434 Gene3D G3DSA:3.40.640.10 193 342 1.5E-46 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS10570 9f1083e49249b9039a44bce5a5287838 434 Pfam PF00202 Aminotransferase class-III 37 431 9.2E-128 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MC49_RS10570 9f1083e49249b9039a44bce5a5287838 434 PIRSF PIRSF000521 37 150 1.7E-6 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MC49_RS10570 9f1083e49249b9039a44bce5a5287838 434 PIRSF PIRSF000521 139 433 6.9E-24 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MC49_RS10570 9f1083e49249b9039a44bce5a5287838 434 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 253 290 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MC49_RS07530 fb4a25a1eea39660a50a20074bbd1c28 310 TIGRFAM TIGR00191 thrB: homoserine kinase 2 307 4.8E-100 T 29-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 MC49_RS07530 fb4a25a1eea39660a50a20074bbd1c28 310 SUPERFAMILY SSF55060 172 288 1.73E-30 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain MC49_RS07530 fb4a25a1eea39660a50a20074bbd1c28 310 Pfam PF00288 GHMP kinases N terminal domain 85 150 4.9E-14 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 MC49_RS07530 fb4a25a1eea39660a50a20074bbd1c28 310 Pfam PF08544 GHMP kinases C terminal 213 287 3.3E-10 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain MC49_RS07530 fb4a25a1eea39660a50a20074bbd1c28 310 PRINTS PR00958 Homoserine kinase signature 254 269 3.5E-31 T 29-03-2018 MC49_RS07530 fb4a25a1eea39660a50a20074bbd1c28 310 PRINTS PR00958 Homoserine kinase signature 9 24 3.5E-31 T 29-03-2018 MC49_RS07530 fb4a25a1eea39660a50a20074bbd1c28 310 PRINTS PR00958 Homoserine kinase signature 137 150 3.5E-31 T 29-03-2018 MC49_RS07530 fb4a25a1eea39660a50a20074bbd1c28 310 PRINTS PR00958 Homoserine kinase signature 175 192 3.5E-31 T 29-03-2018 MC49_RS07530 fb4a25a1eea39660a50a20074bbd1c28 310 PRINTS PR00958 Homoserine kinase signature 97 112 3.5E-31 T 29-03-2018 MC49_RS07530 fb4a25a1eea39660a50a20074bbd1c28 310 PIRSF PIRSF000676 1 309 3.1E-78 T 29-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 MC49_RS07530 fb4a25a1eea39660a50a20074bbd1c28 310 Hamap MF_00384 Homoserine kinase [thrB]. 2 307 28.724 T 29-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 MC49_RS07530 fb4a25a1eea39660a50a20074bbd1c28 310 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 90 101 - T 29-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 MC49_RS07530 fb4a25a1eea39660a50a20074bbd1c28 310 Gene3D G3DSA:3.30.70.890 168 295 7.3E-28 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain MC49_RS07530 fb4a25a1eea39660a50a20074bbd1c28 310 SUPERFAMILY SSF54211 2 161 1.59E-28 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MC49_RS07530 fb4a25a1eea39660a50a20074bbd1c28 310 Gene3D G3DSA:3.30.230.10 1 166 4.8E-23 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MC49_RS03485 5629f6b9480d99de6ebb3a771bc18cbe 337 SUPERFAMILY SSF56655 2 328 2.2E-111 T 29-03-2018 MC49_RS03485 5629f6b9480d99de6ebb3a771bc18cbe 337 PIRSF PIRSF500210 1 332 3.3E-124 T 29-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MC49_RS03485 5629f6b9480d99de6ebb3a771bc18cbe 337 ProSitePatterns PS00124 Fructose-1-6-bisphosphatase active site. 270 282 - T 29-03-2018 IPR020548 Fructose-1,6-bisphosphatase, active site GO:0005975|GO:0042578 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MC49_RS03485 5629f6b9480d99de6ebb3a771bc18cbe 337 Hamap MF_01855 Fructose-1,6-bisphosphatase class 1 [fbp]. 2 330 42.342 T 29-03-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MC49_RS03485 5629f6b9480d99de6ebb3a771bc18cbe 337 Gene3D G3DSA:3.40.190.80 200 331 9.8E-56 T 29-03-2018 MC49_RS03485 5629f6b9480d99de6ebb3a771bc18cbe 337 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 27 54 4.0E-71 T 29-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MC49_RS03485 5629f6b9480d99de6ebb3a771bc18cbe 337 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 64 90 4.0E-71 T 29-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MC49_RS03485 5629f6b9480d99de6ebb3a771bc18cbe 337 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 179 202 4.0E-71 T 29-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MC49_RS03485 5629f6b9480d99de6ebb3a771bc18cbe 337 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 205 232 4.0E-71 T 29-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MC49_RS03485 5629f6b9480d99de6ebb3a771bc18cbe 337 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 148 171 4.0E-71 T 29-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MC49_RS03485 5629f6b9480d99de6ebb3a771bc18cbe 337 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 304 329 4.0E-71 T 29-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MC49_RS03485 5629f6b9480d99de6ebb3a771bc18cbe 337 PIRSF PIRSF000904 1 333 5.2E-121 T 29-03-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MC49_RS03485 5629f6b9480d99de6ebb3a771bc18cbe 337 Gene3D G3DSA:3.30.540.10 6 199 8.7E-61 T 29-03-2018 MC49_RS03485 5629f6b9480d99de6ebb3a771bc18cbe 337 Pfam PF00316 Fructose-1-6-bisphosphatase, N-terminal domain 3 193 3.4E-78 T 29-03-2018 IPR033391 Fructose-1-6-bisphosphatase class I, N-terminal KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MC49_RS11190 14f141dba7037f093e23fe35305fc373 1495 Gene3D G3DSA:1.20.120.330 334 485 7.0E-4 T 29-03-2018 MC49_RS11190 14f141dba7037f093e23fe35305fc373 1495 SUPERFAMILY SSF52540 1268 1433 5.45E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS11190 14f141dba7037f093e23fe35305fc373 1495 SUPERFAMILY SSF52540 21 55 5.45E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS11190 14f141dba7037f093e23fe35305fc373 1495 Gene3D G3DSA:1.20.1170.10 606 968 1.9E-7 T 29-03-2018 MC49_RS11190 14f141dba7037f093e23fe35305fc373 1495 Gene3D G3DSA:1.10.287.620 978 1159 3.8E-6 T 29-03-2018 MC49_RS11190 14f141dba7037f093e23fe35305fc373 1495 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1336 1424 4.2E-15 T 29-03-2018 MC49_RS11190 14f141dba7037f093e23fe35305fc373 1495 SUPERFAMILY SSF52540 22 224 1.59E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS11190 14f141dba7037f093e23fe35305fc373 1495 Pfam PF16330 MukB hinge domain 645 810 4.7E-73 T 29-03-2018 IPR032520 MukB, hinge domain MC49_RS11190 14f141dba7037f093e23fe35305fc373 1495 Gene3D G3DSA:1.10.287.510 491 601 0.014 T 29-03-2018 MC49_RS11190 14f141dba7037f093e23fe35305fc373 1495 PIRSF PIRSF005246 1 1483 0.0 T 29-03-2018 IPR012090 Chromosome partition protein MukB GO:0003677|GO:0005524|GO:0007059|GO:0009295|GO:0030261 MC49_RS11190 14f141dba7037f093e23fe35305fc373 1495 Gene3D G3DSA:3.40.50.300 1160 1436 8.1E-4 T 29-03-2018 MC49_RS11190 14f141dba7037f093e23fe35305fc373 1495 Gene3D G3DSA:3.40.1140.10 1 227 1.2E-9 T 29-03-2018 MC49_RS11190 14f141dba7037f093e23fe35305fc373 1495 Pfam PF04310 MukB N-terminal 2 227 2.0E-120 T 29-03-2018 IPR007406 MukB, N-terminal domain GO:0003677|GO:0005524|GO:0007059|GO:0009295|GO:0030261 MC49_RS07680 98a8e3523aeea4e1f6e6ade4dff8616c 207 PIRSF PIRSF006158 1 206 5.6E-66 T 29-03-2018 IPR016476 SH3 domain protein MC49_RS07680 98a8e3523aeea4e1f6e6ade4dff8616c 207 Gene3D G3DSA:1.20.5.50 90 171 1.6E-8 T 29-03-2018 MC49_RS07680 98a8e3523aeea4e1f6e6ade4dff8616c 207 TIGRFAM TIGR04211 SH3_and_anchor: SH3 domain protein 28 205 6.2E-52 T 29-03-2018 IPR016476 SH3 domain protein MC49_RS07680 98a8e3523aeea4e1f6e6ade4dff8616c 207 Pfam PF08239 Bacterial SH3 domain 35 86 7.4E-8 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type MC49_RS07680 98a8e3523aeea4e1f6e6ade4dff8616c 207 Gene3D G3DSA:2.30.30.410 14 89 1.4E-9 T 29-03-2018 MC49_RS07680 98a8e3523aeea4e1f6e6ade4dff8616c 207 SMART SM00287 24 89 2.4E-9 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type MC49_RS19070 36d0b806e1c44518b1fe851011ad6ae0 342 SUPERFAMILY SSF69369 73 226 6.15E-6 T 29-03-2018 IPR016128 Pyosin/cloacin translocation domain GO:0009405 MC49_RS19070 36d0b806e1c44518b1fe851011ad6ae0 342 SUPERFAMILY SSF69369 274 295 6.15E-6 T 29-03-2018 IPR016128 Pyosin/cloacin translocation domain GO:0009405 MC49_RS19070 36d0b806e1c44518b1fe851011ad6ae0 342 SUPERFAMILY SSF63840 248 342 7.32E-37 T 29-03-2018 IPR009105 Colicin E3-like ribonuclease domain GO:0003723|GO:0009405|GO:0016788|GO:0043022 MC49_RS19070 36d0b806e1c44518b1fe851011ad6ae0 342 Gene3D G3DSA:3.10.380.10 251 339 4.4E-34 T 29-03-2018 IPR009105 Colicin E3-like ribonuclease domain GO:0003723|GO:0009405|GO:0016788|GO:0043022 MC49_RS19070 36d0b806e1c44518b1fe851011ad6ae0 342 Pfam PF03515 Colicin-like bacteriocin tRNase domain 5 246 4.9E-28 T 29-03-2018 IPR016128 Pyosin/cloacin translocation domain GO:0009405 MC49_RS19070 36d0b806e1c44518b1fe851011ad6ae0 342 Pfam PF09000 Cytotoxic 256 339 2.6E-33 T 29-03-2018 IPR009105 Colicin E3-like ribonuclease domain GO:0003723|GO:0009405|GO:0016788|GO:0043022 MC49_RS02690 20b3a80ba5781d4f496e38501b952098 606 Gene3D G3DSA:1.20.120.330 259 587 0.0036 T 29-03-2018 MC49_RS00655 1642d566136eb6695b5216c219577e4d 1058 SUPERFAMILY SSF82693 136 182 4.19E-28 T 29-03-2018 MC49_RS00655 1642d566136eb6695b5216c219577e4d 1058 SUPERFAMILY SSF82693 274 330 4.19E-28 T 29-03-2018 MC49_RS00655 1642d566136eb6695b5216c219577e4d 1058 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 1.2E-111 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS00655 1642d566136eb6695b5216c219577e4d 1058 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 1.2E-111 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS00655 1642d566136eb6695b5216c219577e4d 1058 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 1.2E-111 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS00655 1642d566136eb6695b5216c219577e4d 1058 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 1.2E-111 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS00655 1642d566136eb6695b5216c219577e4d 1058 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 1.2E-111 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS00655 1642d566136eb6695b5216c219577e4d 1058 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 1.2E-111 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS00655 1642d566136eb6695b5216c219577e4d 1058 PRINTS PR00702 Acriflavin resistance protein family signature 622 636 1.2E-111 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS00655 1642d566136eb6695b5216c219577e4d 1058 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 1.2E-111 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS00655 1642d566136eb6695b5216c219577e4d 1058 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 1.2E-111 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS00655 1642d566136eb6695b5216c219577e4d 1058 Gene3D G3DSA:3.30.2090.10 180 275 4.5E-17 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MC49_RS00655 1642d566136eb6695b5216c219577e4d 1058 SUPERFAMILY SSF82866 296 497 7.06E-48 T 29-03-2018 MC49_RS00655 1642d566136eb6695b5216c219577e4d 1058 SUPERFAMILY SSF82693 813 861 2.88E-26 T 29-03-2018 MC49_RS00655 1642d566136eb6695b5216c219577e4d 1058 SUPERFAMILY SSF82693 673 723 2.88E-26 T 29-03-2018 MC49_RS00655 1642d566136eb6695b5216c219577e4d 1058 SUPERFAMILY SSF82693 38 131 5.06E-27 T 29-03-2018 MC49_RS00655 1642d566136eb6695b5216c219577e4d 1058 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1050 0.0 T 29-03-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 MC49_RS00655 1642d566136eb6695b5216c219577e4d 1058 SUPERFAMILY SSF82714 182 272 2.22E-21 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MC49_RS00655 1642d566136eb6695b5216c219577e4d 1058 Gene3D G3DSA:3.30.70.1440 673 770 6.8E-16 T 29-03-2018 MC49_RS00655 1642d566136eb6695b5216c219577e4d 1058 Gene3D G3DSA:3.30.70.1430 568 669 5.9E-19 T 29-03-2018 MC49_RS00655 1642d566136eb6695b5216c219577e4d 1058 Gene3D G3DSA:1.20.1640.10 287 510 2.1E-42 T 29-03-2018 MC49_RS00655 1642d566136eb6695b5216c219577e4d 1058 SUPERFAMILY SSF82714 725 807 6.02E-19 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MC49_RS00655 1642d566136eb6695b5216c219577e4d 1058 Pfam PF00873 AcrB/AcrD/AcrF family 1 1032 0.0 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS00655 1642d566136eb6695b5216c219577e4d 1058 Gene3D G3DSA:3.30.70.1430 38 140 7.4E-28 T 29-03-2018 MC49_RS00655 1642d566136eb6695b5216c219577e4d 1058 SUPERFAMILY SSF82866 839 1032 4.19E-45 T 29-03-2018 MC49_RS00655 1642d566136eb6695b5216c219577e4d 1058 Gene3D G3DSA:1.20.1640.10 819 1035 1.3E-38 T 29-03-2018 MC49_RS00655 1642d566136eb6695b5216c219577e4d 1058 SUPERFAMILY SSF82693 566 670 5.02E-31 T 29-03-2018 MC49_RS06125 8bd7bf23ae8b57f629e5b29d6811b23e 537 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 80 102 - T 29-03-2018 IPR023765 Solute-binding protein family 5, conserved site MC49_RS06125 8bd7bf23ae8b57f629e5b29d6811b23e 537 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 74 454 3.0E-109 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain MC49_RS06125 8bd7bf23ae8b57f629e5b29d6811b23e 537 Gene3D G3DSA:3.10.105.10 301 508 2.2E-64 T 29-03-2018 MC49_RS06125 8bd7bf23ae8b57f629e5b29d6811b23e 537 PIRSF PIRSF002741 4 537 1.2E-120 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MC49_RS06125 8bd7bf23ae8b57f629e5b29d6811b23e 537 Gene3D G3DSA:3.40.190.10 205 300 5.5E-30 T 29-03-2018 MC49_RS06125 8bd7bf23ae8b57f629e5b29d6811b23e 537 SUPERFAMILY SSF53850 30 535 1.54E-161 T 29-03-2018 MC49_RS06125 8bd7bf23ae8b57f629e5b29d6811b23e 537 Gene3D G3DSA:3.90.76.10 39 204 2.6E-38 T 29-03-2018 MC49_RS10840 85bd0cd81faf4ac77c06b982cfe8a086 470 Gene3D G3DSA:1.10.1040.10 180 434 1.6E-114 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MC49_RS10840 85bd0cd81faf4ac77c06b982cfe8a086 470 SUPERFAMILY SSF48179 176 469 7.48E-134 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MC49_RS10840 85bd0cd81faf4ac77c06b982cfe8a086 470 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 167 195 1.5E-89 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MC49_RS10840 85bd0cd81faf4ac77c06b982cfe8a086 470 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 66 95 1.5E-89 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MC49_RS10840 85bd0cd81faf4ac77c06b982cfe8a086 470 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 248 275 1.5E-89 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MC49_RS10840 85bd0cd81faf4ac77c06b982cfe8a086 470 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 4 27 1.5E-89 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MC49_RS10840 85bd0cd81faf4ac77c06b982cfe8a086 470 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 119 144 1.5E-89 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MC49_RS10840 85bd0cd81faf4ac77c06b982cfe8a086 470 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 356 378 1.5E-89 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MC49_RS10840 85bd0cd81faf4ac77c06b982cfe8a086 470 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 5 467 1.3E-231 T 29-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MC49_RS10840 85bd0cd81faf4ac77c06b982cfe8a086 470 SUPERFAMILY SSF51735 4 175 6.26E-52 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS10840 85bd0cd81faf4ac77c06b982cfe8a086 470 Gene3D G3DSA:3.40.50.720 1 179 3.1E-33 T 29-03-2018 MC49_RS10840 85bd0cd81faf4ac77c06b982cfe8a086 470 Gene3D G3DSA:1.20.5.320 435 468 9.7E-21 T 29-03-2018 MC49_RS10840 85bd0cd81faf4ac77c06b982cfe8a086 470 PIRSF PIRSF000109 1 470 4.1E-243 T 29-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MC49_RS10840 85bd0cd81faf4ac77c06b982cfe8a086 470 SMART SM01350 178 467 2.6E-225 T 29-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MC49_RS10840 85bd0cd81faf4ac77c06b982cfe8a086 470 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 178 466 2.9E-134 T 29-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MC49_RS10840 85bd0cd81faf4ac77c06b982cfe8a086 470 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 173 3.8E-52 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 MC49_RS10840 85bd0cd81faf4ac77c06b982cfe8a086 470 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 252 264 - T 29-03-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MC49_RS13905 ce0b1c8cffe133eb8fae76c6ff1dd87d 291 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 8 280 30.936 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 MC49_RS13905 ce0b1c8cffe133eb8fae76c6ff1dd87d 291 SUPERFAMILY SSF54211 7 166 1.29E-45 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MC49_RS13905 ce0b1c8cffe133eb8fae76c6ff1dd87d 291 Gene3D G3DSA:3.30.70.890 170 287 8.2E-24 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain MC49_RS13905 ce0b1c8cffe133eb8fae76c6ff1dd87d 291 Pfam PF08544 GHMP kinases C terminal 203 262 5.9E-5 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain MC49_RS13905 ce0b1c8cffe133eb8fae76c6ff1dd87d 291 Gene3D G3DSA:3.30.230.10 8 169 1.1E-41 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MC49_RS13905 ce0b1c8cffe133eb8fae76c6ff1dd87d 291 Pfam PF00288 GHMP kinases N terminal domain 96 153 1.6E-8 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 MC49_RS13905 ce0b1c8cffe133eb8fae76c6ff1dd87d 291 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 7 285 2.3E-97 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 MC49_RS13905 ce0b1c8cffe133eb8fae76c6ff1dd87d 291 SUPERFAMILY SSF55060 169 286 1.08E-34 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain MC49_RS13905 ce0b1c8cffe133eb8fae76c6ff1dd87d 291 PIRSF PIRSF010376 6 288 3.3E-80 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 MC49_RS11050 aaad6442bad238143241bb2271831ac1 588 Pfam PF00664 ABC transporter transmembrane region 86 267 2.1E-13 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MC49_RS11050 aaad6442bad238143241bb2271831ac1 588 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 7 534 3.7E-155 T 29-03-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 MC49_RS11050 aaad6442bad238143241bb2271831ac1 588 Gene3D G3DSA:3.40.50.300 327 575 2.9E-66 T 29-03-2018 MC49_RS11050 aaad6442bad238143241bb2271831ac1 588 ProSitePatterns PS00211 ABC transporters family signature. 476 490 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS11050 aaad6442bad238143241bb2271831ac1 588 SMART SM00382 365 575 1.7E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS11050 aaad6442bad238143241bb2271831ac1 588 SUPERFAMILY SSF90123 7 327 1.28E-38 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MC49_RS11050 aaad6442bad238143241bb2271831ac1 588 SUPERFAMILY SSF52540 335 572 2.07E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS11050 aaad6442bad238143241bb2271831ac1 588 Gene3D G3DSA:1.20.1560.10 1 326 1.1E-28 T 29-03-2018 MC49_RS11050 aaad6442bad238143241bb2271831ac1 588 Pfam PF00005 ABC transporter 356 503 4.1E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS02290 ff5e5e49cab2807e9609957ea1eb6eb5 78 Pfam PF11660 Protein of unknown function (DUF3262) 2 75 1.0E-15 T 29-03-2018 IPR021676 Protein of unknown function DUF3262 MC49_RS02290 ff5e5e49cab2807e9609957ea1eb6eb5 78 TIGRFAM TIGR03758 conj_TIGR03758: integrating conjugative element protein, PFL_4701 family 2 76 9.6E-17 T 29-03-2018 IPR021676 Protein of unknown function DUF3262 MC49_RS02990 cfaaec639564b2ff64245bfe5c4afe68 166 Pfam PF00583 Acetyltransferase (GNAT) family 42 149 6.9E-17 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MC49_RS02990 cfaaec639564b2ff64245bfe5c4afe68 166 Gene3D G3DSA:3.40.630.30 37 159 2.4E-24 T 29-03-2018 MC49_RS02990 cfaaec639564b2ff64245bfe5c4afe68 166 SUPERFAMILY SSF55729 22 150 2.29E-31 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS07815 8c3a70e5431e75a25aff3b2c7da02c1b 216 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 6 212 5.7E-60 T 29-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS07815 8c3a70e5431e75a25aff3b2c7da02c1b 216 Gene3D G3DSA:3.30.2350.10 11 215 1.1E-60 T 29-03-2018 MC49_RS07815 8c3a70e5431e75a25aff3b2c7da02c1b 216 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 58 72 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS07815 8c3a70e5431e75a25aff3b2c7da02c1b 216 SUPERFAMILY SSF55120 6 213 4.32E-64 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS07815 8c3a70e5431e75a25aff3b2c7da02c1b 216 Pfam PF00849 RNA pseudouridylate synthase 21 166 3.6E-28 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS11930 fb2e4272ec92521c321ca5f8bb396a86 179 Pfam PF12790 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 14 169 8.0E-34 T 29-03-2018 IPR017734 Type VI secretion system, lipoprotein SciN MC49_RS11930 fb2e4272ec92521c321ca5f8bb396a86 179 TIGRFAM TIGR03352 VI_chp_3: type VI secretion lipoprotein, VC_A0113 family 9 171 3.1E-38 T 29-03-2018 IPR017734 Type VI secretion system, lipoprotein SciN MC49_RS09005 202e1e398e0d757ee0bf1ff3fe4fbf31 568 SUPERFAMILY SSF52540 321 556 9.4E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS09005 202e1e398e0d757ee0bf1ff3fe4fbf31 568 Pfam PF00664 ABC transporter transmembrane region 24 278 3.8E-6 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MC49_RS09005 202e1e398e0d757ee0bf1ff3fe4fbf31 568 ProSitePatterns PS00211 ABC transporters family signature. 469 483 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS09005 202e1e398e0d757ee0bf1ff3fe4fbf31 568 SUPERFAMILY SSF90123 13 318 2.49E-40 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MC49_RS09005 202e1e398e0d757ee0bf1ff3fe4fbf31 568 Pfam PF00005 ABC transporter 348 496 6.6E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS09005 202e1e398e0d757ee0bf1ff3fe4fbf31 568 SMART SM00382 357 553 9.0E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS09005 202e1e398e0d757ee0bf1ff3fe4fbf31 568 TIGRFAM TIGR01842 type_I_sec_PrtD: type I secretion system ATPase 15 557 6.2E-204 T 29-03-2018 IPR010128 ATPase, type I secretion system, PrtD GO:0005524|GO:0008565|GO:0016021|GO:0030253|GO:0030256 MC49_RS09005 202e1e398e0d757ee0bf1ff3fe4fbf31 568 Gene3D G3DSA:3.40.50.300 323 568 3.5E-61 T 29-03-2018 MC49_RS09005 202e1e398e0d757ee0bf1ff3fe4fbf31 568 Gene3D G3DSA:1.20.1560.10 5 317 3.8E-19 T 29-03-2018 MC49_RS01050 e8f496d90d651bed79493ab5450feff1 451 TIGRFAM TIGR02783 TrbL_P: P-type conjugative transfer protein TrbL 1 306 1.2E-65 T 29-03-2018 IPR014150 Conjugal transfer, TrbL MC49_RS01050 e8f496d90d651bed79493ab5450feff1 451 Gene3D G3DSA:1.20.120.20 94 414 1.5E-4 T 29-03-2018 MC49_RS01050 e8f496d90d651bed79493ab5450feff1 451 Pfam PF04610 TrbL/VirB6 plasmid conjugal transfer protein 37 256 4.0E-52 T 29-03-2018 IPR007688 Plasmid conjugal transfer TrbL/VirB6 GO:0030255 MC49_RS10015 0aabe7c634ce97b102fe07db84fc10c4 171 Pfam PF01047 MarR family 57 116 2.8E-16 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MC49_RS10015 0aabe7c634ce97b102fe07db84fc10c4 171 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 108 7.9E-23 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MC49_RS10015 0aabe7c634ce97b102fe07db84fc10c4 171 PRINTS PR00598 Bacterial regulatory protein MarR family signature 142 162 7.9E-23 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MC49_RS10015 0aabe7c634ce97b102fe07db84fc10c4 171 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 92 7.9E-23 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MC49_RS10015 0aabe7c634ce97b102fe07db84fc10c4 171 PRINTS PR00598 Bacterial regulatory protein MarR family signature 112 128 7.9E-23 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MC49_RS10015 0aabe7c634ce97b102fe07db84fc10c4 171 SMART SM00347 50 152 2.0E-27 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MC49_RS10015 0aabe7c634ce97b102fe07db84fc10c4 171 SUPERFAMILY SSF46785 27 167 1.2E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS10015 0aabe7c634ce97b102fe07db84fc10c4 171 ProSitePatterns PS01117 MarR-type HTH domain signature. 91 125 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site MC49_RS10015 0aabe7c634ce97b102fe07db84fc10c4 171 Gene3D G3DSA:1.10.10.10 28 165 5.0E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS15985 eb486682b9ea2039ed9452feee709edf 643 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 634 33.915 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MC49_RS15985 eb486682b9ea2039ed9452feee709edf 643 Gene3D G3DSA:3.10.20.30 1 64 2.6E-18 T 29-03-2018 IPR012675 Beta-grasp domain MC49_RS15985 eb486682b9ea2039ed9452feee709edf 643 Gene3D G3DSA:3.30.930.10 223 531 4.0E-120 T 29-03-2018 MC49_RS15985 eb486682b9ea2039ed9452feee709edf 643 Pfam PF02824 TGS domain 4 61 1.4E-11 T 29-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 MC49_RS15985 eb486682b9ea2039ed9452feee709edf 643 Pfam PF03129 Anticodon binding domain 541 630 2.0E-22 T 29-03-2018 IPR004154 Anticodon-binding MC49_RS15985 eb486682b9ea2039ed9452feee709edf 643 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 318 528 6.0E-51 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS15985 eb486682b9ea2039ed9452feee709edf 643 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 631 2.7E-243 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MC49_RS15985 eb486682b9ea2039ed9452feee709edf 643 SUPERFAMILY SSF81271 3 61 1.31E-15 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 MC49_RS15985 eb486682b9ea2039ed9452feee709edf 643 SUPERFAMILY SSF52954 530 634 8.0E-33 T 29-03-2018 IPR004154 Anticodon-binding MC49_RS15985 eb486682b9ea2039ed9452feee709edf 643 Gene3D G3DSA:3.30.980.10 65 145 2.4E-21 T 29-03-2018 MC49_RS15985 eb486682b9ea2039ed9452feee709edf 643 Gene3D G3DSA:3.30.980.10 146 222 4.7E-17 T 29-03-2018 MC49_RS15985 eb486682b9ea2039ed9452feee709edf 643 SMART SM00863 170 219 1.1E-17 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 MC49_RS15985 eb486682b9ea2039ed9452feee709edf 643 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 172 219 2.6E-13 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 MC49_RS15985 eb486682b9ea2039ed9452feee709edf 643 Gene3D G3DSA:3.40.50.800 532 642 7.3E-28 T 29-03-2018 IPR004154 Anticodon-binding MC49_RS15985 eb486682b9ea2039ed9452feee709edf 643 SUPERFAMILY SSF55186 63 241 6.41E-64 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 MC49_RS15985 eb486682b9ea2039ed9452feee709edf 643 SUPERFAMILY SSF55681 243 525 2.81E-95 T 29-03-2018 MC49_RS15985 eb486682b9ea2039ed9452feee709edf 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 507 520 1.6E-54 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MC49_RS15985 eb486682b9ea2039ed9452feee709edf 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 362 385 1.6E-54 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MC49_RS15985 eb486682b9ea2039ed9452feee709edf 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 329 357 1.6E-54 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MC49_RS15985 eb486682b9ea2039ed9452feee709edf 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 464 492 1.6E-54 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MC49_RS15985 eb486682b9ea2039ed9452feee709edf 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 534 546 1.6E-54 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MC49_RS08560 ebc3ac3714934f80c8187cbd35cba373 281 SUPERFAMILY SSF89028 101 259 4.51E-13 T 29-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 MC49_RS08560 ebc3ac3714934f80c8187cbd35cba373 281 Gene3D G3DSA:1.20.1200.10 102 266 8.5E-20 T 29-03-2018 MC49_RS08560 ebc3ac3714934f80c8187cbd35cba373 281 Pfam PF01923 Cobalamin adenosyltransferase 103 256 2.1E-13 T 29-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 MC49_RS08560 ebc3ac3714934f80c8187cbd35cba373 281 PIRSF PIRSF012294 1 262 4.1E-90 T 29-03-2018 IPR009194 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase, EutT-type GO:0005524|GO:0006580|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 MC49_RS04420 c7fd2bb0929e0f672f2bb17acf31233a 277 Pfam PF12122 Cytoplasmic N-terminal domain of rhomboid serine protease 1 83 1.6E-26 T 29-03-2018 IPR022732 Peptidase S54, GlpG peptidase, N-terminal GO:0004252|GO:0016021 MC49_RS04420 c7fd2bb0929e0f672f2bb17acf31233a 277 TIGRFAM TIGR04239 rhombo_GlpG: rhomboid family protease GlpG 4 273 3.1E-106 T 29-03-2018 IPR023662 Rhomboid protease GlpG GO:0004252|GO:0006508|GO:0016021 MC49_RS04420 c7fd2bb0929e0f672f2bb17acf31233a 277 Hamap MF_01594 Rhomboid protease GlpG [glpG]. 1 277 44.545 T 29-03-2018 IPR023662 Rhomboid protease GlpG GO:0004252|GO:0006508|GO:0016021 MC49_RS04420 c7fd2bb0929e0f672f2bb17acf31233a 277 SUPERFAMILY SSF144091 96 274 1.83E-41 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 MC49_RS04420 c7fd2bb0929e0f672f2bb17acf31233a 277 Pfam PF01694 Rhomboid family 132 273 6.2E-30 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 MC49_RS04420 c7fd2bb0929e0f672f2bb17acf31233a 277 Gene3D G3DSA:1.20.1540.10 96 274 2.2E-36 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 MC49_RS08830 263674031fbe79a8ce68b0bb2712352e 209 Gene3D G3DSA:1.10.10.10 145 200 9.7E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS08830 263674031fbe79a8ce68b0bb2712352e 209 Pfam PF00072 Response regulator receiver domain 17 118 2.4E-8 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS08830 263674031fbe79a8ce68b0bb2712352e 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 144 197 5.7E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS08830 263674031fbe79a8ce68b0bb2712352e 209 SMART SM00421 142 199 8.7E-18 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS08830 263674031fbe79a8ce68b0bb2712352e 209 SUPERFAMILY SSF46894 133 197 6.46E-17 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MC49_RS08830 263674031fbe79a8ce68b0bb2712352e 209 Gene3D G3DSA:3.40.50.2300 15 144 5.2E-13 T 29-03-2018 MC49_RS08830 263674031fbe79a8ce68b0bb2712352e 209 SUPERFAMILY SSF52172 18 168 1.85E-14 T 29-03-2018 IPR011006 CheY-like superfamily MC49_RS08830 263674031fbe79a8ce68b0bb2712352e 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 187 1.9E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS08830 263674031fbe79a8ce68b0bb2712352e 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 175 1.9E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS08830 263674031fbe79a8ce68b0bb2712352e 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 145 159 1.9E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS03065 99cf3a7d2438c8c28b92e92e94854b0d 149 SUPERFAMILY SSF55804 5 142 1.92E-28 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 MC49_RS03065 99cf3a7d2438c8c28b92e92e94854b0d 149 Gene3D G3DSA:3.40.930.10 4 144 9.4E-24 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 MC49_RS03065 99cf3a7d2438c8c28b92e92e94854b0d 149 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 142 1.6E-25 T 29-03-2018 IPR002178 PTS EIIA type-2 domain MC49_RS05420 1a216e2d99bb8b32e679495ae2a038cd 803 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 715 742 - T 29-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 MC49_RS05420 1a216e2d99bb8b32e679495ae2a038cd 803 SUPERFAMILY SSF53706 1 638 3.4E-234 T 29-03-2018 MC49_RS05420 1a216e2d99bb8b32e679495ae2a038cd 803 TIGRFAM TIGR01553 formate-DH-alph: formate dehydrogenase-N alpha subunit 1 802 0.0 T 29-03-2018 IPR006443 Formate dehydrogenase-N, alpha subunit GO:0008863|GO:0009055|GO:0043546|GO:0045333|GO:0047111 MC49_RS05420 1a216e2d99bb8b32e679495ae2a038cd 803 Pfam PF01568 Molydopterin dinucleotide binding domain 681 796 9.4E-16 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 MC49_RS05420 1a216e2d99bb8b32e679495ae2a038cd 803 Gene3D G3DSA:3.40.50.740 269 449 1.7E-27 T 29-03-2018 MC49_RS05420 1a216e2d99bb8b32e679495ae2a038cd 803 Gene3D G3DSA:3.40.228.10 1 268 5.3E-69 T 29-03-2018 MC49_RS05420 1a216e2d99bb8b32e679495ae2a038cd 803 Gene3D G3DSA:2.40.40.20 628 803 9.8E-39 T 29-03-2018 MC49_RS05420 1a216e2d99bb8b32e679495ae2a038cd 803 SUPERFAMILY SSF50692 674 803 7.25E-43 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain MC49_RS05420 1a216e2d99bb8b32e679495ae2a038cd 803 SUPERFAMILY SSF50692 617 647 7.25E-43 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain MC49_RS05420 1a216e2d99bb8b32e679495ae2a038cd 803 Pfam PF00384 Molybdopterin oxidoreductase 2 378 2.3E-21 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS05420 1a216e2d99bb8b32e679495ae2a038cd 803 Gene3D G3DSA:3.40.228.10 529 627 4.2E-14 T 29-03-2018 MC49_RS00695 89e40176af4efbb0b09f41eff4984bc5 598 SUPERFAMILY SSF90123 15 331 6.15E-68 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MC49_RS00695 89e40176af4efbb0b09f41eff4984bc5 598 SUPERFAMILY SSF52540 341 582 6.2E-77 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS00695 89e40176af4efbb0b09f41eff4984bc5 598 SMART SM00382 372 573 3.2E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS00695 89e40176af4efbb0b09f41eff4984bc5 598 Gene3D G3DSA:3.40.50.300 334 587 4.9E-68 T 29-03-2018 MC49_RS00695 89e40176af4efbb0b09f41eff4984bc5 598 Pfam PF00005 ABC transporter 363 511 4.1E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS00695 89e40176af4efbb0b09f41eff4984bc5 598 Gene3D G3DSA:1.20.1560.10 1 333 2.9E-64 T 29-03-2018 MC49_RS00695 89e40176af4efbb0b09f41eff4984bc5 598 Pfam PF00664 ABC transporter transmembrane region 32 301 2.2E-40 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MC49_RS11780 3a3fe0dfb89d33c3420e462fc8cfcd8b 247 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 121 127 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MC49_RS11780 3a3fe0dfb89d33c3420e462fc8cfcd8b 247 Pfam PF05175 Methyltransferase small domain 45 171 5.8E-13 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 MC49_RS11780 3a3fe0dfb89d33c3420e462fc8cfcd8b 247 Hamap MF_01872 tRNA1(Val) (adenine(37)-N6)-methyltransferase [yfiC]. 12 247 51.974 T 29-03-2018 IPR022882 tRNA1(Val) (adenine(37)-N6)-methyltransferase GO:0016430 KEGG: 00340+2.1.1.22 MC49_RS11780 3a3fe0dfb89d33c3420e462fc8cfcd8b 247 Gene3D G3DSA:3.40.50.150 33 241 4.4E-32 T 29-03-2018 MC49_RS11780 3a3fe0dfb89d33c3420e462fc8cfcd8b 247 SUPERFAMILY SSF53335 19 190 5.97E-30 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS01295 0d26c3ad12dad53d4a688dbbd7d47c24 113 Hamap MF_00213 Probable hydrogenase nickel incorporation protein HypA [hypA]. 1 113 24.126 T 29-03-2018 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 MC49_RS01295 0d26c3ad12dad53d4a688dbbd7d47c24 113 ProSitePatterns PS01249 Hydrogenases expression/synthesis hypA family signature. 34 76 - T 29-03-2018 IPR020538 Hydrogenase nickel incorporation protein HypA/HybF, conserved site MC49_RS01295 0d26c3ad12dad53d4a688dbbd7d47c24 113 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 111 7.1E-33 T 29-03-2018 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 MC49_RS01295 0d26c3ad12dad53d4a688dbbd7d47c24 113 TIGRFAM TIGR00100 hypA: hydrogenase nickel insertion protein HypA 1 111 5.2E-38 T 29-03-2018 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 MC49_RS01295 0d26c3ad12dad53d4a688dbbd7d47c24 113 PIRSF PIRSF004761 1 113 7.7E-38 T 29-03-2018 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 MC49_RS08930 2070bdde894d5ab6b1c4ea21ce639218 538 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 9 36 0.0014 T 29-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal MC49_RS08930 2070bdde894d5ab6b1c4ea21ce639218 538 SUPERFAMILY SSF51556 115 428 1.36E-56 T 29-03-2018 IPR032466 Metal-dependent hydrolase MC49_RS08930 2070bdde894d5ab6b1c4ea21ce639218 538 Gene3D G3DSA:2.30.40.10 44 131 1.6E-18 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS08930 2070bdde894d5ab6b1c4ea21ce639218 538 SUPERFAMILY SSF51338 427 501 2.55E-22 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS08930 2070bdde894d5ab6b1c4ea21ce639218 538 SUPERFAMILY SSF51338 60 115 2.55E-22 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS08930 2070bdde894d5ab6b1c4ea21ce639218 538 Pfam PF01979 Amidohydrolase family 112 474 3.6E-32 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MC49_RS08930 2070bdde894d5ab6b1c4ea21ce639218 538 Gene3D G3DSA:3.20.20.140 132 443 4.1E-46 T 29-03-2018 MC49_RS08360 8544d8be47d413ba5277a3d3f529ea01 208 PIRSF PIRSF000709 4 181 3.4E-15 T 29-03-2018 MC49_RS08360 8544d8be47d413ba5277a3d3f529ea01 208 SMART SM00855 5 161 8.3E-23 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MC49_RS08360 8544d8be47d413ba5277a3d3f529ea01 208 SUPERFAMILY SSF53254 1 202 3.77E-58 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MC49_RS08360 8544d8be47d413ba5277a3d3f529ea01 208 Gene3D G3DSA:3.40.50.1240 3 206 1.7E-52 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MC49_RS08360 8544d8be47d413ba5277a3d3f529ea01 208 TIGRFAM TIGR03162 ribazole_cobC: alpha-ribazole phosphatase 7 184 2.6E-54 T 29-03-2018 IPR017578 Alpha-ribazole phosphatase, CobC GO:0009236|GO:0043755 KEGG: 00860+3.1.3.73|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 MC49_RS08360 8544d8be47d413ba5277a3d3f529ea01 208 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 198 6.9E-54 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MC49_RS08360 8544d8be47d413ba5277a3d3f529ea01 208 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 8 17 - T 29-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 MC49_RS03720 b782751002cb3d4072b5c69534a98d09 274 Gene3D G3DSA:3.10.310.10 125 261 2.0E-48 T 29-03-2018 MC49_RS03720 b782751002cb3d4072b5c69534a98d09 274 Pfam PF01678 Diaminopimelate epimerase 152 267 3.2E-29 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MC49_RS03720 b782751002cb3d4072b5c69534a98d09 274 Pfam PF01678 Diaminopimelate epimerase 3 123 8.6E-34 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MC49_RS03720 b782751002cb3d4072b5c69534a98d09 274 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 1 273 6.0E-99 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MC49_RS03720 b782751002cb3d4072b5c69534a98d09 274 SUPERFAMILY SSF54506 1 272 7.46E-52 T 29-03-2018 MC49_RS03720 b782751002cb3d4072b5c69534a98d09 274 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 1 274 39.222 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MC49_RS03720 b782751002cb3d4072b5c69534a98d09 274 Gene3D G3DSA:3.10.310.10 1 124 2.8E-47 T 29-03-2018 MC49_RS03720 b782751002cb3d4072b5c69534a98d09 274 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 64 78 - T 29-03-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MC49_RS18290 8f535b331b6b84ad623588b0373a06fc 274 SUPERFAMILY SSF46689 170 219 3.58E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS18290 8f535b331b6b84ad623588b0373a06fc 274 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 253 269 2.5E-7 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MC49_RS18290 8f535b331b6b84ad623588b0373a06fc 274 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 238 253 2.5E-7 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MC49_RS18290 8f535b331b6b84ad623588b0373a06fc 274 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 223 265 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MC49_RS18290 8f535b331b6b84ad623588b0373a06fc 274 SMART SM00342 186 269 8.6E-28 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MC49_RS18290 8f535b331b6b84ad623588b0373a06fc 274 Pfam PF12833 Helix-turn-helix domain 193 269 1.2E-19 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MC49_RS18290 8f535b331b6b84ad623588b0373a06fc 274 SUPERFAMILY SSF46689 222 272 2.78E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS18290 8f535b331b6b84ad623588b0373a06fc 274 Gene3D G3DSA:1.10.10.60 165 222 8.4E-9 T 29-03-2018 MC49_RS18290 8f535b331b6b84ad623588b0373a06fc 274 Gene3D G3DSA:1.10.10.60 223 272 4.7E-11 T 29-03-2018 MC49_RS14015 471d8e683650875c7c4bfd5051987608 250 SUPERFAMILY SSF110395 3 243 2.22E-75 T 29-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 MC49_RS14015 471d8e683650875c7c4bfd5051987608 250 Gene3D G3DSA:3.20.20.380 1 249 1.2E-89 T 29-03-2018 MC49_RS14015 471d8e683650875c7c4bfd5051987608 250 Pfam PF03932 CutC family 3 200 1.9E-72 T 29-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 MC49_RS14015 471d8e683650875c7c4bfd5051987608 250 Hamap MF_00795 Copper homeostasis protein CutC [cutC]. 2 243 38.763 T 29-03-2018 IPR005627 Copper homeostasis protein CutC GO:0005507|GO:0055070 Reactome: R-HSA-936837 MC49_RS06000 29a9fe5fb21381940ce98ecc3b98edbe 484 Gene3D G3DSA:3.40.50.2300 1 148 5.0E-37 T 29-03-2018 MC49_RS06000 29a9fe5fb21381940ce98ecc3b98edbe 484 SMART SM00382 161 304 1.3E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS06000 29a9fe5fb21381940ce98ecc3b98edbe 484 TIGRFAM TIGR01818 ntrC: nitrogen regulation protein NR(I) 6 471 4.5E-227 T 29-03-2018 IPR010114 Signal transduction response regulator, nitrogen regulation NR(I) GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0006808 MC49_RS06000 29a9fe5fb21381940ce98ecc3b98edbe 484 Pfam PF00158 Sigma-54 interaction domain 141 307 5.0E-70 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MC49_RS06000 29a9fe5fb21381940ce98ecc3b98edbe 484 Gene3D G3DSA:1.10.8.60 314 383 1.5E-21 T 29-03-2018 MC49_RS06000 29a9fe5fb21381940ce98ecc3b98edbe 484 Gene3D G3DSA:3.40.50.300 149 313 1.2E-28 T 29-03-2018 MC49_RS06000 29a9fe5fb21381940ce98ecc3b98edbe 484 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 165 178 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MC49_RS06000 29a9fe5fb21381940ce98ecc3b98edbe 484 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 227 242 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MC49_RS06000 29a9fe5fb21381940ce98ecc3b98edbe 484 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 455 475 1.2E-8 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MC49_RS06000 29a9fe5fb21381940ce98ecc3b98edbe 484 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 438 455 1.2E-8 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MC49_RS06000 29a9fe5fb21381940ce98ecc3b98edbe 484 Pfam PF00072 Response regulator receiver domain 6 114 3.9E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS06000 29a9fe5fb21381940ce98ecc3b98edbe 484 SUPERFAMILY SSF46689 399 475 1.66E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS06000 29a9fe5fb21381940ce98ecc3b98edbe 484 Gene3D G3DSA:1.10.10.60 384 475 4.4E-23 T 29-03-2018 MC49_RS06000 29a9fe5fb21381940ce98ecc3b98edbe 484 SMART SM00448 4 115 1.4E-37 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS06000 29a9fe5fb21381940ce98ecc3b98edbe 484 SUPERFAMILY SSF52172 1 186 3.42E-48 T 29-03-2018 IPR011006 CheY-like superfamily MC49_RS06000 29a9fe5fb21381940ce98ecc3b98edbe 484 SUPERFAMILY SSF52540 140 383 7.7E-73 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS06000 29a9fe5fb21381940ce98ecc3b98edbe 484 Pfam PF02954 Bacterial regulatory protein, Fis family 432 471 1.8E-13 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MC49_RS06965 779a4a061d33934e677370e87e85cae7 360 Pfam PF00589 Phage integrase family 214 346 6.7E-16 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MC49_RS06965 779a4a061d33934e677370e87e85cae7 360 Gene3D G3DSA:1.10.150.130 65 163 9.9E-7 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal MC49_RS06965 779a4a061d33934e677370e87e85cae7 360 SUPERFAMILY SSF56349 69 354 5.0E-46 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MC49_RS06965 779a4a061d33934e677370e87e85cae7 360 Gene3D G3DSA:1.10.443.10 178 360 2.3E-28 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MC49_RS03545 da552d74ce5217a10e549153e2b3c9c1 75 PRINTS PR00974 Ribosomal protein S18 family signature 46 60 3.9E-19 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS03545 da552d74ce5217a10e549153e2b3c9c1 75 PRINTS PR00974 Ribosomal protein S18 family signature 38 45 3.9E-19 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS03545 da552d74ce5217a10e549153e2b3c9c1 75 PRINTS PR00974 Ribosomal protein S18 family signature 28 38 3.9E-19 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS03545 da552d74ce5217a10e549153e2b3c9c1 75 PRINTS PR00974 Ribosomal protein S18 family signature 60 70 3.9E-19 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS03545 da552d74ce5217a10e549153e2b3c9c1 75 SUPERFAMILY SSF46911 3 74 3.53E-29 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS03545 da552d74ce5217a10e549153e2b3c9c1 75 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 2 73 21.622 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS03545 da552d74ce5217a10e549153e2b3c9c1 75 Pfam PF01084 Ribosomal protein S18 19 68 2.5E-25 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS03545 da552d74ce5217a10e549153e2b3c9c1 75 Gene3D G3DSA:4.10.640.10 1 75 4.5E-32 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS03545 da552d74ce5217a10e549153e2b3c9c1 75 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 21 73 1.0E-22 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS03545 da552d74ce5217a10e549153e2b3c9c1 75 ProSitePatterns PS00057 Ribosomal protein S18 signature. 21 44 - T 29-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS03545 da552d74ce5217a10e549153e2b3c9c1 75 TIGRFAM TIGR00165 S18: ribosomal protein bS18 4 72 4.9E-38 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS09680 d4a14bf020bfed96429942630b5fc48f 365 Gene3D G3DSA:3.40.50.1980 153 325 3.1E-30 T 29-03-2018 MC49_RS09680 d4a14bf020bfed96429942630b5fc48f 365 Gene3D G3DSA:3.40.50.1980 24 152 3.2E-25 T 29-03-2018 MC49_RS09680 d4a14bf020bfed96429942630b5fc48f 365 SUPERFAMILY SSF53807 28 353 2.63E-53 T 29-03-2018 MC49_RS09680 d4a14bf020bfed96429942630b5fc48f 365 Pfam PF01497 Periplasmic binding protein 92 290 4.8E-23 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 MC49_RS09350 8d23a97decbd16f67c8a094df39a6684 666 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 57 503 3.3E-161 T 29-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 MC49_RS09350 8d23a97decbd16f67c8a094df39a6684 666 ProSitePatterns PS01303 BCCT family of transporters signature. 321 330 - T 29-03-2018 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 MC49_RS09350 8d23a97decbd16f67c8a094df39a6684 666 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 19 502 1.2E-192 T 29-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 MC49_RS18140 cfa845fbbb3148e364d613ce72cb087f 288 SUPERFAMILY SSF53474 31 279 2.75E-45 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS18140 cfa845fbbb3148e364d613ce72cb087f 288 Pfam PF00756 Putative esterase 48 193 2.4E-16 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 MC49_RS18140 cfa845fbbb3148e364d613ce72cb087f 288 Gene3D G3DSA:3.40.50.1820 26 288 6.1E-23 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS16350 de1ea07da17ff73a2a2ec2a44e03ecb2 265 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 5 261 1.2E-98 T 29-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MC49_RS16350 de1ea07da17ff73a2a2ec2a44e03ecb2 265 Pfam PF08543 Phosphomethylpyrimidine kinase 12 259 3.6E-91 T 29-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 MC49_RS16350 de1ea07da17ff73a2a2ec2a44e03ecb2 265 Gene3D G3DSA:3.40.1190.20 2 265 1.9E-59 T 29-03-2018 IPR029056 Ribokinase-like MC49_RS16350 de1ea07da17ff73a2a2ec2a44e03ecb2 265 SUPERFAMILY SSF53613 5 265 2.49E-75 T 29-03-2018 IPR029056 Ribokinase-like MC49_RS18590 f841ec71d80423189e5bcf96753b3b25 250 Pfam PF07072 Cell division protein 22 228 1.8E-71 T 29-03-2018 IPR009777 Cell division protein ZapD MC49_RS18590 f841ec71d80423189e5bcf96753b3b25 250 Gene3D G3DSA:1.10.3900.10 16 177 1.3E-53 T 29-03-2018 MC49_RS18590 f841ec71d80423189e5bcf96753b3b25 250 Hamap MF_01092 Cell division protein ZapD [zapD]. 7 250 30.892 T 29-03-2018 IPR009777 Cell division protein ZapD MC49_RS18590 f841ec71d80423189e5bcf96753b3b25 250 SUPERFAMILY SSF160950 7 250 2.75E-83 T 29-03-2018 IPR009777 Cell division protein ZapD MC49_RS18590 f841ec71d80423189e5bcf96753b3b25 250 Gene3D G3DSA:2.60.440.10 178 250 4.2E-25 T 29-03-2018 IPR027462 Z ring-associated protein D, C-terminal domain MC49_RS05225 4453cfa1a4f7dd36bc565661744089df 771 Gene3D G3DSA:3.40.50.300 385 535 2.8E-11 T 29-03-2018 MC49_RS05225 4453cfa1a4f7dd36bc565661744089df 771 Pfam PF13588 Type I restriction enzyme R protein N terminus (HSDR_N) 44 113 1.2E-7 T 29-03-2018 IPR029464 Type I restriction enzyme R protein, N-terminal domain MC49_RS05225 4453cfa1a4f7dd36bc565661744089df 771 Pfam PF08463 EcoEI R protein C-terminal 607 768 9.0E-24 T 29-03-2018 IPR013670 EcoEI R protein C-terminal domain GO:0003677|GO:0003824|GO:0006304 MC49_RS05225 4453cfa1a4f7dd36bc565661744089df 771 Pfam PF04851 Type III restriction enzyme, res subunit 147 320 6.5E-37 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MC49_RS05225 4453cfa1a4f7dd36bc565661744089df 771 Pfam PF00271 Helicase conserved C-terminal domain 404 511 9.3E-6 T 29-03-2018 IPR001650 Helicase, C-terminal MC49_RS05225 4453cfa1a4f7dd36bc565661744089df 771 SMART SM00487 145 356 3.8E-15 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MC49_RS05225 4453cfa1a4f7dd36bc565661744089df 771 Gene3D G3DSA:3.40.50.300 122 342 1.2E-24 T 29-03-2018 MC49_RS05225 4453cfa1a4f7dd36bc565661744089df 771 SUPERFAMILY SSF52540 161 321 1.28E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS05225 4453cfa1a4f7dd36bc565661744089df 771 SUPERFAMILY SSF52540 378 514 1.28E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS07760 802ff0e7e11ebe5e72b25324bf3b4f38 475 SUPERFAMILY SSF49503 316 469 3.59E-20 T 29-03-2018 IPR008972 Cupredoxin MC49_RS07760 802ff0e7e11ebe5e72b25324bf3b4f38 475 SUPERFAMILY SSF49503 35 172 6.11E-25 T 29-03-2018 IPR008972 Cupredoxin MC49_RS07760 802ff0e7e11ebe5e72b25324bf3b4f38 475 Pfam PF07731 Multicopper oxidase 347 471 2.1E-15 T 29-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 MC49_RS07760 802ff0e7e11ebe5e72b25324bf3b4f38 475 Pfam PF07732 Multicopper oxidase 54 169 9.7E-27 T 29-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 MC49_RS07760 802ff0e7e11ebe5e72b25324bf3b4f38 475 Hamap MF_00915 Cell division protein FtsP [ftsP]. 1 470 56.01 T 29-03-2018 IPR026589 Cell division protein FtsP GO:0043093 MC49_RS07760 802ff0e7e11ebe5e72b25324bf3b4f38 475 SUPERFAMILY SSF49503 174 290 6.68E-25 T 29-03-2018 IPR008972 Cupredoxin MC49_RS07760 802ff0e7e11ebe5e72b25324bf3b4f38 475 Gene3D G3DSA:2.60.40.420 31 172 2.2E-23 T 29-03-2018 IPR008972 Cupredoxin MC49_RS07760 802ff0e7e11ebe5e72b25324bf3b4f38 475 Gene3D G3DSA:2.60.40.420 173 320 6.4E-23 T 29-03-2018 IPR008972 Cupredoxin MC49_RS07760 802ff0e7e11ebe5e72b25324bf3b4f38 475 Gene3D G3DSA:2.60.40.420 353 475 1.3E-18 T 29-03-2018 IPR008972 Cupredoxin MC49_RS15350 f267d9b37d517d7f4e5a754d0cbba7ff 337 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 234 9.5E-57 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MC49_RS15350 f267d9b37d517d7f4e5a754d0cbba7ff 337 Gene3D G3DSA:3.90.25.10 191 337 2.6E-36 T 29-03-2018 MC49_RS15350 f267d9b37d517d7f4e5a754d0cbba7ff 337 PRINTS PR01713 Nucleotide sugar epimerase signature 256 271 2.2E-25 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 MC49_RS15350 f267d9b37d517d7f4e5a754d0cbba7ff 337 PRINTS PR01713 Nucleotide sugar epimerase signature 216 231 2.2E-25 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 MC49_RS15350 f267d9b37d517d7f4e5a754d0cbba7ff 337 PRINTS PR01713 Nucleotide sugar epimerase signature 29 45 2.2E-25 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 MC49_RS15350 f267d9b37d517d7f4e5a754d0cbba7ff 337 PRINTS PR01713 Nucleotide sugar epimerase signature 295 312 2.2E-25 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 MC49_RS15350 f267d9b37d517d7f4e5a754d0cbba7ff 337 Gene3D G3DSA:3.40.50.720 2 190 1.5E-38 T 29-03-2018 MC49_RS15350 f267d9b37d517d7f4e5a754d0cbba7ff 337 SUPERFAMILY SSF51735 1 335 9.09E-92 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS01010 b37a62ef932db8e1d6c35c8697dd83c6 599 SMART SM00493 280 351 2.1E-21 T 29-03-2018 IPR006171 TOPRIM domain MC49_RS01010 b37a62ef932db8e1d6c35c8697dd83c6 599 SMART SM00766 470 595 7.3E-42 T 29-03-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 MC49_RS01010 b37a62ef932db8e1d6c35c8697dd83c6 599 Pfam PF10410 DnaB-helicase binding domain of primase 390 443 9.4E-11 T 29-03-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 MC49_RS01010 b37a62ef932db8e1d6c35c8697dd83c6 599 SUPERFAMILY SSF57783 25 121 3.06E-35 T 29-03-2018 MC49_RS01010 b37a62ef932db8e1d6c35c8697dd83c6 599 SUPERFAMILY SSF56731 137 447 1.03E-112 T 29-03-2018 MC49_RS01010 b37a62ef932db8e1d6c35c8697dd83c6 599 SMART SM00400 57 111 2.1E-36 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 MC49_RS01010 b37a62ef932db8e1d6c35c8697dd83c6 599 Gene3D G3DSA:3.90.580.10 22 123 1.4E-33 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 MC49_RS01010 b37a62ef932db8e1d6c35c8697dd83c6 599 Pfam PF13155 Toprim-like 284 369 1.4E-14 T 29-03-2018 MC49_RS01010 b37a62ef932db8e1d6c35c8697dd83c6 599 Hamap MF_00974 DNA primase [dnaG]. 25 596 29.99 T 29-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 MC49_RS01010 b37a62ef932db8e1d6c35c8697dd83c6 599 Pfam PF08278 DNA primase DnaG DnaB-binding 471 592 4.0E-31 T 29-03-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 MC49_RS01010 b37a62ef932db8e1d6c35c8697dd83c6 599 Gene3D G3DSA:3.90.980.10 130 261 1.9E-46 T 29-03-2018 IPR013264 DNA primase, catalytic core, N-terminal MC49_RS01010 b37a62ef932db8e1d6c35c8697dd83c6 599 TIGRFAM TIGR01391 dnaG: DNA primase 25 439 3.6E-150 T 29-03-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 MC49_RS01010 b37a62ef932db8e1d6c35c8697dd83c6 599 Pfam PF01807 CHC2 zinc finger 27 121 1.4E-38 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 MC49_RS01010 b37a62ef932db8e1d6c35c8697dd83c6 599 Gene3D G3DSA:1.20.50.20 391 438 5.5E-17 T 29-03-2018 MC49_RS01010 b37a62ef932db8e1d6c35c8697dd83c6 599 SUPERFAMILY SSF117023 467 596 4.05E-39 T 29-03-2018 MC49_RS01010 b37a62ef932db8e1d6c35c8697dd83c6 599 Pfam PF08275 DNA primase catalytic core, N-terminal domain 147 272 1.5E-43 T 29-03-2018 IPR013264 DNA primase, catalytic core, N-terminal MC49_RS01010 b37a62ef932db8e1d6c35c8697dd83c6 599 Gene3D G3DSA:1.10.860.10 454 599 2.2E-34 T 29-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal MC49_RS01010 b37a62ef932db8e1d6c35c8697dd83c6 599 Gene3D G3DSA:3.40.1360.20 276 390 5.4E-32 T 29-03-2018 MC49_RS07110 fce86b24ec7cf0ea4804c6264f010401 545 Hamap MF_00414 Probable protein kinase UbiB [ubiB]. 3 538 56.943 T 29-03-2018 IPR010232 Probable protein kinase UbiB GO:0006744 MC49_RS07110 fce86b24ec7cf0ea4804c6264f010401 545 Gene3D G3DSA:3.30.200.20 103 243 6.4E-21 T 29-03-2018 MC49_RS07110 fce86b24ec7cf0ea4804c6264f010401 545 Pfam PF03109 ABC1 family 113 230 5.3E-35 T 29-03-2018 IPR004147 UbiB domain MC49_RS07110 fce86b24ec7cf0ea4804c6264f010401 545 SUPERFAMILY SSF56112 94 158 1.51E-49 T 29-03-2018 IPR011009 Protein kinase-like domain MC49_RS07110 fce86b24ec7cf0ea4804c6264f010401 545 SUPERFAMILY SSF56112 192 435 1.51E-49 T 29-03-2018 IPR011009 Protein kinase-like domain MC49_RS07110 fce86b24ec7cf0ea4804c6264f010401 545 TIGRFAM TIGR01982 UbiB: 2-polyprenylphenol 6-hydroxylase 6 445 2.2E-181 T 29-03-2018 IPR010232 Probable protein kinase UbiB GO:0006744 MC49_RS08715 dfcd3bb2bd72e59b112f3db4c9c78694 538 Pfam PF02625 XdhC and CoxI family 11 73 1.8E-15 T 29-03-2018 IPR003777 XdhC- CoxI MC49_RS08715 dfcd3bb2bd72e59b112f3db4c9c78694 538 Gene3D G3DSA:2.40.50.100 408 458 0.06 T 29-03-2018 MC49_RS08715 dfcd3bb2bd72e59b112f3db4c9c78694 538 Gene3D G3DSA:2.40.50.100 459 504 0.0018 T 29-03-2018 MC49_RS08715 dfcd3bb2bd72e59b112f3db4c9c78694 538 TIGRFAM TIGR03309 matur_yqeB: selenium-dependent molybdenum hydroxylase system protein, YqeB family 272 527 3.9E-113 T 29-03-2018 IPR017695 Selenium-dependent molybdenum hydroxylase system protein, YqeB family MC49_RS08715 dfcd3bb2bd72e59b112f3db4c9c78694 538 Pfam PF13478 XdhC Rossmann domain 106 247 6.0E-31 T 29-03-2018 IPR027051 XdhC Rossmann domain MC49_RS08715 dfcd3bb2bd72e59b112f3db4c9c78694 538 Gene3D G3DSA:3.40.50.720 194 407 7.5E-5 T 29-03-2018 MC49_RS08715 dfcd3bb2bd72e59b112f3db4c9c78694 538 Gene3D G3DSA:3.40.50.20 104 193 0.02 T 29-03-2018 MC49_RS02710 314555756b9700785796e5652c686f27 253 TIGRFAM TIGR01401 fliR_like_III: type III secretion apparatus protein SpaR/YscT/HrcT 9 236 1.8E-50 T 29-03-2018 IPR006304 Type III secretion protein SpaR/YscT GO:0006810|GO:0016021 MC49_RS02710 314555756b9700785796e5652c686f27 253 Pfam PF01311 Bacterial export proteins, family 1 14 229 2.7E-41 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 MC49_RS02710 314555756b9700785796e5652c686f27 253 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 75 94 5.4E-17 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 MC49_RS02710 314555756b9700785796e5652c686f27 253 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 174 196 5.4E-17 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 MC49_RS02710 314555756b9700785796e5652c686f27 253 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 20 41 5.4E-17 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 MC49_RS02710 314555756b9700785796e5652c686f27 253 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 196 215 5.4E-17 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 MC49_RS16145 b6e20782b659e45a3df7b14125f60f37 299 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 7 295 62.585 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MC49_RS16145 b6e20782b659e45a3df7b14125f60f37 299 SMART SM01130 7 297 7.1E-133 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MC49_RS16145 b6e20782b659e45a3df7b14125f60f37 299 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 10 294 2.7E-112 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MC49_RS16145 b6e20782b659e45a3df7b14125f60f37 299 Pfam PF00701 Dihydrodipicolinate synthetase family 8 295 5.7E-110 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MC49_RS16145 b6e20782b659e45a3df7b14125f60f37 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 77 95 2.1E-33 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MC49_RS16145 b6e20782b659e45a3df7b14125f60f37 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 109 125 2.1E-33 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MC49_RS16145 b6e20782b659e45a3df7b14125f60f37 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 134 151 2.1E-33 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MC49_RS16145 b6e20782b659e45a3df7b14125f60f37 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 41 62 2.1E-33 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MC49_RS16145 b6e20782b659e45a3df7b14125f60f37 299 SUPERFAMILY SSF51569 8 297 3.56E-95 T 29-03-2018 MC49_RS16145 b6e20782b659e45a3df7b14125f60f37 299 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 139 169 - T 29-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 MC49_RS16145 b6e20782b659e45a3df7b14125f60f37 299 Gene3D G3DSA:3.20.20.70 3 299 3.9E-87 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS16145 b6e20782b659e45a3df7b14125f60f37 299 PIRSF PIRSF001365 7 299 1.4E-90 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MC49_RS16145 b6e20782b659e45a3df7b14125f60f37 299 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 44 61 - T 29-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MC49_RS04760 83cae831f44487f8171088592c1210dd 232 PIRSF PIRSF006232 1 230 1.9E-56 T 29-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 MC49_RS04760 83cae831f44487f8171088592c1210dd 232 Gene3D G3DSA:2.60.120.10 12 131 1.5E-47 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MC49_RS04760 83cae831f44487f8171088592c1210dd 232 SUPERFAMILY SSF51182 1 230 9.35E-80 T 29-03-2018 IPR011051 RmlC-like cupin domain MC49_RS04760 83cae831f44487f8171088592c1210dd 232 Gene3D G3DSA:2.60.120.10 132 232 2.3E-24 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MC49_RS04760 83cae831f44487f8171088592c1210dd 232 Pfam PF02678 Pirin 7 119 3.6E-36 T 29-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 MC49_RS05950 a446b214a3b5ed680fc8fdf9f8d45999 407 Gene3D G3DSA:3.90.1260.10 172 362 1.1E-80 T 29-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MC49_RS05950 a446b214a3b5ed680fc8fdf9f8d45999 407 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 125 136 - T 29-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MC49_RS05950 a446b214a3b5ed680fc8fdf9f8d45999 407 Hamap MF_00005 Argininosuccinate synthase [argG]. 9 406 50.452 T 29-03-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MC49_RS05950 a446b214a3b5ed680fc8fdf9f8d45999 407 Gene3D G3DSA:3.40.50.620 2 171 3.5E-24 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS05950 a446b214a3b5ed680fc8fdf9f8d45999 407 Pfam PF00764 Arginosuccinate synthase 13 400 7.2E-141 T 29-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MC49_RS05950 a446b214a3b5ed680fc8fdf9f8d45999 407 SUPERFAMILY SSF69864 180 405 1.44E-86 T 29-03-2018 MC49_RS05950 a446b214a3b5ed680fc8fdf9f8d45999 407 Gene3D G3DSA:1.20.5.470 372 404 5.0E-14 T 29-03-2018 MC49_RS05950 a446b214a3b5ed680fc8fdf9f8d45999 407 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 15 23 - T 29-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MC49_RS05950 a446b214a3b5ed680fc8fdf9f8d45999 407 TIGRFAM TIGR00032 argG: argininosuccinate synthase 11 400 3.1E-133 T 29-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MC49_RS05950 a446b214a3b5ed680fc8fdf9f8d45999 407 SUPERFAMILY SSF52402 10 174 1.0E-43 T 29-03-2018 MC49_RS05470 4f9bfe0ac342f471f62b329ad2d8f5ff 467 Gene3D G3DSA:1.20.1250.20 6 202 1.4E-22 T 29-03-2018 MC49_RS05470 4f9bfe0ac342f471f62b329ad2d8f5ff 467 SUPERFAMILY SSF103473 5 199 1.57E-39 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS05470 4f9bfe0ac342f471f62b329ad2d8f5ff 467 SUPERFAMILY SSF103473 249 460 1.57E-39 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS05470 4f9bfe0ac342f471f62b329ad2d8f5ff 467 Pfam PF07690 Major Facilitator Superfamily 23 416 1.6E-29 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS05470 4f9bfe0ac342f471f62b329ad2d8f5ff 467 Gene3D G3DSA:1.20.1250.20 261 462 2.1E-9 T 29-03-2018 MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 Gene3D G3DSA:3.40.1110.10 615 723 6.7E-34 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 Pfam PF00702 haloacid dehalogenase-like hydrolase 595 810 8.9E-50 T 29-03-2018 MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 827 852 1.9E-7 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 768 784 1.9E-7 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 796 812 1.9E-7 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 743 753 6.9E-25 T 29-03-2018 MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 598 612 6.9E-25 T 29-03-2018 MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 721 732 6.9E-25 T 29-03-2018 MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 796 815 6.9E-25 T 29-03-2018 MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 446 460 6.9E-25 T 29-03-2018 MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 819 831 6.9E-25 T 29-03-2018 MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 Gene3D G3DSA:3.40.50.1000 724 861 7.9E-45 T 29-03-2018 IPR023214 HAD-like domain MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 Pfam PF00403 Heavy-metal-associated domain 73 127 3.5E-7 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 Pfam PF00403 Heavy-metal-associated domain 8 62 3.3E-10 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 Pfam PF00403 Heavy-metal-associated domain 180 236 6.5E-16 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 368 875 1.9E-85 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 Gene3D G3DSA:3.30.70.100 70 141 2.6E-11 T 29-03-2018 MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 Gene3D G3DSA:3.30.70.100 1 69 1.3E-13 T 29-03-2018 MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 329 905 1.8E-182 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 SUPERFAMILY SSF55008 178 244 3.01E-19 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 600 606 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 SUPERFAMILY SSF56784 653 902 2.13E-59 T 29-03-2018 IPR023214 HAD-like domain MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 SUPERFAMILY SSF56784 596 616 2.13E-59 T 29-03-2018 IPR023214 HAD-like domain MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 Gene3D G3DSA:1.20.1110.10 363 614 1.9E-45 T 29-03-2018 MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 ProSitePatterns PS01047 Heavy-metal-associated domain. 182 211 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 SUPERFAMILY SSF81653 399 496 2.35E-25 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 Gene3D G3DSA:3.30.70.100 173 244 8.4E-22 T 29-03-2018 MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 SUPERFAMILY SSF55008 71 133 2.23E-10 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 SUPERFAMILY SSF55008 3 65 1.7E-12 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 Pfam PF00122 E1-E2 ATPase 397 577 3.2E-50 T 29-03-2018 MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 310 905 4.7E-189 T 29-03-2018 MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 ProSitePatterns PS01229 Hypothetical cof family signature 2. 796 818 - T 29-03-2018 MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 ProSitePatterns PS01047 Heavy-metal-associated domain. 9 38 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 SUPERFAMILY SSF81665 363 400 1.83E-10 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 SUPERFAMILY SSF81665 845 855 1.83E-10 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MC49_RS00540 96591a9281f3592853b3a5e52b04c9bf 912 SUPERFAMILY SSF81665 497 592 1.83E-10 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MC49_RS01875 cbe8c185a3072f0fe6f48713155aaa32 117 Pfam PF10694 Protein of unknown function (DUF2500) 6 114 1.1E-26 T 29-03-2018 IPR019635 Protein of unknown function DUF2500 MC49_RS07960 c152d507435ca30dbe3244ffaf19ddd5 365 SUPERFAMILY SSF53335 184 279 9.48E-12 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS07960 c152d507435ca30dbe3244ffaf19ddd5 365 PIRSF PIRSF028774 1 359 1.6E-187 T 29-03-2018 IPR011224 Ribosomal RNA large subunit methyltransferase M GO:0008168 MC49_RS07960 c152d507435ca30dbe3244ffaf19ddd5 365 Pfam PF01728 FtsJ-like methyltransferase 186 260 1.8E-7 T 29-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 MC49_RS07960 c152d507435ca30dbe3244ffaf19ddd5 365 Hamap MF_01551 Ribosomal RNA large subunit methyltransferase M [rlmM]. 1 355 83.609 T 29-03-2018 IPR011224 Ribosomal RNA large subunit methyltransferase M GO:0008168 MC49_RS07960 c152d507435ca30dbe3244ffaf19ddd5 365 Gene3D G3DSA:3.40.50.150 176 357 1.4E-19 T 29-03-2018 MC49_RS06460 7fec40be3d61a0c8c89d7e39d25aa6b6 255 Hamap MF_00443 Thiazole synthase [thiG]. 1 253 42.513 T 29-03-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 MC49_RS06460 7fec40be3d61a0c8c89d7e39d25aa6b6 255 Gene3D G3DSA:3.20.20.70 1 254 1.3E-55 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS06460 7fec40be3d61a0c8c89d7e39d25aa6b6 255 Pfam PF05690 Thiazole biosynthesis protein ThiG 4 247 1.3E-108 T 29-03-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 MC49_RS06460 7fec40be3d61a0c8c89d7e39d25aa6b6 255 SUPERFAMILY SSF110399 1 238 2.35E-83 T 29-03-2018 MC49_RS15645 d8ac1fb4d8ba6a637ee0199e2ff0b706 201 SUPERFAMILY SSF52833 1 79 1.6E-18 T 29-03-2018 IPR012336 Thioredoxin-like fold MC49_RS15645 d8ac1fb4d8ba6a637ee0199e2ff0b706 201 Pfam PF02798 Glutathione S-transferase, N-terminal domain 3 74 1.7E-12 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MC49_RS15645 d8ac1fb4d8ba6a637ee0199e2ff0b706 201 Pfam PF00043 Glutathione S-transferase, C-terminal domain 93 189 3.7E-15 T 29-03-2018 IPR004046 Glutathione S-transferase, C-terminal MC49_RS15645 d8ac1fb4d8ba6a637ee0199e2ff0b706 201 SUPERFAMILY SSF47616 84 198 1.67E-29 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like MC49_RS15645 d8ac1fb4d8ba6a637ee0199e2ff0b706 201 Gene3D G3DSA:3.40.30.10 1 98 4.6E-21 T 29-03-2018 MC49_RS15645 d8ac1fb4d8ba6a637ee0199e2ff0b706 201 Gene3D G3DSA:1.20.1050.10 99 199 4.7E-22 T 29-03-2018 MC49_RS10665 a82d11907b68ffa856dc3084eeb06805 448 SUPERFAMILY SSF52540 74 360 1.31E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS10665 a82d11907b68ffa856dc3084eeb06805 448 SMART SM00487 20 222 3.6E-60 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MC49_RS10665 a82d11907b68ffa856dc3084eeb06805 448 Gene3D G3DSA:3.40.50.300 1 224 2.6E-59 T 29-03-2018 MC49_RS10665 a82d11907b68ffa856dc3084eeb06805 448 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 153 161 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site MC49_RS10665 a82d11907b68ffa856dc3084eeb06805 448 Pfam PF00271 Helicase conserved C-terminal domain 233 338 1.7E-25 T 29-03-2018 IPR001650 Helicase, C-terminal MC49_RS10665 a82d11907b68ffa856dc3084eeb06805 448 SMART SM00490 258 339 1.8E-29 T 29-03-2018 IPR001650 Helicase, C-terminal MC49_RS10665 a82d11907b68ffa856dc3084eeb06805 448 Gene3D G3DSA:3.40.50.300 225 435 7.6E-46 T 29-03-2018 MC49_RS10665 a82d11907b68ffa856dc3084eeb06805 448 Pfam PF00270 DEAD/DEAH box helicase 25 194 1.7E-47 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MC49_RS10665 a82d11907b68ffa856dc3084eeb06805 448 Hamap MF_00968 ATP-dependent RNA helicase RhlE [rhlE]. 1 435 48.421 T 29-03-2018 IPR028622 ATP-dependent RNA helicase RhlE GO:0004004|GO:0042255 MC49_RS10380 9e23f5994bc3f384017cf56c298963d2 934 Gene3D G3DSA:1.10.287.1150 83 165 3.9E-23 T 29-03-2018 MC49_RS10380 9e23f5994bc3f384017cf56c298963d2 934 SUPERFAMILY SSF52518 574 792 1.1E-52 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MC49_RS10380 9e23f5994bc3f384017cf56c298963d2 934 Gene3D G3DSA:3.40.50.970 591 800 7.3E-57 T 29-03-2018 MC49_RS10380 9e23f5994bc3f384017cf56c298963d2 934 SUPERFAMILY SSF52518 119 528 1.01E-86 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MC49_RS10380 9e23f5994bc3f384017cf56c298963d2 934 Pfam PF00676 Dehydrogenase E1 component 219 513 2.1E-50 T 29-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 MC49_RS10380 9e23f5994bc3f384017cf56c298963d2 934 PIRSF PIRSF000157 1 933 0.0 T 29-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MC49_RS10380 9e23f5994bc3f384017cf56c298963d2 934 SMART SM00861 592 785 1.4E-62 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MC49_RS10380 9e23f5994bc3f384017cf56c298963d2 934 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 12 50 2.5E-17 T 29-03-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MC49_RS10380 9e23f5994bc3f384017cf56c298963d2 934 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 14 931 0.0 T 29-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MC49_RS10380 9e23f5994bc3f384017cf56c298963d2 934 Gene3D G3DSA:3.40.50.970 166 518 1.1E-89 T 29-03-2018 MC49_RS10380 9e23f5994bc3f384017cf56c298963d2 934 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 789 931 5.2E-54 T 29-03-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MC49_RS10380 9e23f5994bc3f384017cf56c298963d2 934 Pfam PF02779 Transketolase, pyrimidine binding domain 592 786 7.2E-66 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MC49_RS04065 abf9b327d97f70b20a5d2fe3f2ee0bdd 144 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 143 2.4E-31 T 29-03-2018 IPR021131 Ribosomal protein L18e/L15P MC49_RS04065 abf9b327d97f70b20a5d2fe3f2ee0bdd 144 SUPERFAMILY SSF52080 4 143 2.35E-46 T 29-03-2018 IPR021131 Ribosomal protein L18e/L15P MC49_RS04065 abf9b327d97f70b20a5d2fe3f2ee0bdd 144 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 144 19.307 T 29-03-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 MC49_RS04065 abf9b327d97f70b20a5d2fe3f2ee0bdd 144 Gene3D G3DSA:3.100.10.10 42 144 8.6E-25 T 29-03-2018 MC49_RS04065 abf9b327d97f70b20a5d2fe3f2ee0bdd 144 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 143 5.8E-50 T 29-03-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS11895 9678fc03434fdfb2fb1ca40c4ad66864 1182 Gene3D G3DSA:3.40.50.300 105 894 3.4E-4 T 29-03-2018 MC49_RS11895 9678fc03434fdfb2fb1ca40c4ad66864 1182 Pfam PF06744 Type VI secretion protein IcmF C-terminal 934 1130 2.0E-54 T 29-03-2018 IPR010623 Type VI secretion system IcmF, C-terminal MC49_RS11895 9678fc03434fdfb2fb1ca40c4ad66864 1182 Pfam PF14331 ImcF-related N-terminal domain 213 461 1.6E-61 T 29-03-2018 IPR025743 ImcF-related, N-terminal domain MC49_RS11895 9678fc03434fdfb2fb1ca40c4ad66864 1182 Pfam PF06761 Intracellular multiplication and human macrophage-killing 515 828 4.0E-70 T 29-03-2018 IPR009612 ImcF-related MC49_RS11895 9678fc03434fdfb2fb1ca40c4ad66864 1182 TIGRFAM TIGR03348 VI_IcmF: type VI secretion protein IcmF 36 1179 1.9E-286 T 29-03-2018 IPR017731 Type VI secretion system, IcmF MC49_RS17125 7d4cb3d0d2a53de0b80cfec28969b828 196 PIRSF PIRSF006305 1 193 4.6E-42 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 MC49_RS17125 7d4cb3d0d2a53de0b80cfec28969b828 196 Pfam PF02545 Maf-like protein 4 185 1.9E-41 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 MC49_RS17125 7d4cb3d0d2a53de0b80cfec28969b828 196 Gene3D G3DSA:3.90.950.10 2 194 7.3E-54 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MC49_RS17125 7d4cb3d0d2a53de0b80cfec28969b828 196 TIGRFAM TIGR00172 maf: septum formation protein Maf 3 184 1.1E-54 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 MC49_RS17125 7d4cb3d0d2a53de0b80cfec28969b828 196 SUPERFAMILY SSF52972 2 185 1.05E-56 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MC49_RS17125 7d4cb3d0d2a53de0b80cfec28969b828 196 Hamap MF_00528 Septum formation protein Maf [maf]. 3 191 28.275 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 MC49_RS05545 2b77ccf9978e466f0df7051038c70bd1 224 Pfam PF04002 RadC-like JAB domain 104 222 2.9E-44 T 29-03-2018 IPR025657 RadC-like JAB domain MC49_RS05545 2b77ccf9978e466f0df7051038c70bd1 224 TIGRFAM TIGR00608 radc: DNA repair protein RadC 11 222 2.2E-77 T 29-03-2018 IPR001405 RadC protein MC49_RS05545 2b77ccf9978e466f0df7051038c70bd1 224 SUPERFAMILY SSF47781 17 90 2.3E-8 T 29-03-2018 IPR010994 RuvA domain 2-like MC49_RS05545 2b77ccf9978e466f0df7051038c70bd1 224 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 173 178 - T 29-03-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site MC49_RS05545 2b77ccf9978e466f0df7051038c70bd1 224 Gene3D G3DSA:3.40.140.10 99 224 9.0E-47 T 29-03-2018 MC49_RS08790 dabb7e5530dd2ce74907bc5090490953 616 SUPERFAMILY SSF55781 36 119 3.73E-5 T 29-03-2018 IPR029016 GAF domain-like MC49_RS08790 dabb7e5530dd2ce74907bc5090490953 616 Gene3D G3DSA:3.40.50.300 269 447 9.0E-29 T 29-03-2018 MC49_RS08790 dabb7e5530dd2ce74907bc5090490953 616 Pfam PF02954 Bacterial regulatory protein, Fis family 572 611 4.6E-13 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MC49_RS08790 dabb7e5530dd2ce74907bc5090490953 616 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 299 312 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MC49_RS08790 dabb7e5530dd2ce74907bc5090490953 616 Gene3D G3DSA:3.30.450.20 143 229 2.7E-5 T 29-03-2018 MC49_RS08790 dabb7e5530dd2ce74907bc5090490953 616 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 362 377 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MC49_RS08790 dabb7e5530dd2ce74907bc5090490953 616 Pfam PF00158 Sigma-54 interaction domain 275 442 1.4E-70 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MC49_RS08790 dabb7e5530dd2ce74907bc5090490953 616 Gene3D G3DSA:1.10.10.60 577 613 1.2E-14 T 29-03-2018 MC49_RS08790 dabb7e5530dd2ce74907bc5090490953 616 SUPERFAMILY SSF52540 275 518 6.16E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS08790 dabb7e5530dd2ce74907bc5090490953 616 SUPERFAMILY SSF46689 563 614 1.43E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS08790 dabb7e5530dd2ce74907bc5090490953 616 Gene3D G3DSA:1.10.8.60 448 576 6.4E-20 T 29-03-2018 MC49_RS08790 dabb7e5530dd2ce74907bc5090490953 616 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 489 498 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site MC49_RS08790 dabb7e5530dd2ce74907bc5090490953 616 SMART SM00382 295 439 3.1E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS17195 0275602f3058ba5b00a15dee48309a79 374 Gene3D G3DSA:3.40.50.1980 165 350 2.3E-40 T 29-03-2018 MC49_RS17195 0275602f3058ba5b00a15dee48309a79 374 SUPERFAMILY SSF53807 31 366 3.92E-55 T 29-03-2018 MC49_RS17195 0275602f3058ba5b00a15dee48309a79 374 Gene3D G3DSA:3.40.50.1980 20 164 1.6E-22 T 29-03-2018 MC49_RS17195 0275602f3058ba5b00a15dee48309a79 374 Pfam PF01497 Periplasmic binding protein 93 318 1.6E-21 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 MC49_RS14630 7d2a17b202edab752a9bc648a412f6b2 535 SMART SM00382 26 228 2.3E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS14630 7d2a17b202edab752a9bc648a412f6b2 535 SMART SM00382 345 513 6.7E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS14630 7d2a17b202edab752a9bc648a412f6b2 535 SUPERFAMILY SSF52540 297 523 9.41E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS14630 7d2a17b202edab752a9bc648a412f6b2 535 Pfam PF12848 ABC transporter 224 309 1.5E-18 T 29-03-2018 IPR032781 ABC-transporter extension domain MC49_RS14630 7d2a17b202edab752a9bc648a412f6b2 535 Pfam PF00005 ABC transporter 337 468 1.4E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS14630 7d2a17b202edab752a9bc648a412f6b2 535 Pfam PF00005 ABC transporter 18 184 1.5E-18 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS14630 7d2a17b202edab752a9bc648a412f6b2 535 SUPERFAMILY SSF52540 5 239 2.91E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS14630 7d2a17b202edab752a9bc648a412f6b2 535 Gene3D G3DSA:3.40.50.300 3 283 5.7E-50 T 29-03-2018 MC49_RS14630 7d2a17b202edab752a9bc648a412f6b2 535 Gene3D G3DSA:3.40.50.300 284 535 1.2E-47 T 29-03-2018 MC49_RS12570 a27399e6f603b84ce5787944923aa6d4 317 Pfam PF03466 LysR substrate binding domain 96 301 3.4E-28 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS12570 a27399e6f603b84ce5787944923aa6d4 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 69 3.9E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS12570 a27399e6f603b84ce5787944923aa6d4 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 5.6E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS12570 a27399e6f603b84ce5787944923aa6d4 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 5.6E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS12570 a27399e6f603b84ce5787944923aa6d4 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 5.6E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS12570 a27399e6f603b84ce5787944923aa6d4 317 SUPERFAMILY SSF46785 10 92 6.14E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS12570 a27399e6f603b84ce5787944923aa6d4 317 Gene3D G3DSA:1.10.10.10 3 93 1.2E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS12570 a27399e6f603b84ce5787944923aa6d4 317 Gene3D G3DSA:3.40.190.10 182 272 3.4E-20 T 29-03-2018 MC49_RS12570 a27399e6f603b84ce5787944923aa6d4 317 SUPERFAMILY SSF53850 96 304 2.68E-35 T 29-03-2018 MC49_RS12570 a27399e6f603b84ce5787944923aa6d4 317 Gene3D G3DSA:3.40.190.10 95 181 1.4E-4 T 29-03-2018 MC49_RS11165 f65d04b7982954a51b4340a16f8b676d 249 Gene3D G3DSA:3.90.550.10 1 249 2.9E-50 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MC49_RS11165 f65d04b7982954a51b4340a16f8b676d 249 Pfam PF02348 Cytidylyltransferase 4 220 3.5E-66 T 29-03-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 MC49_RS11165 f65d04b7982954a51b4340a16f8b676d 249 Hamap MF_00057 8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase [kdsB]. 1 247 43.994 T 29-03-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 MC49_RS11165 f65d04b7982954a51b4340a16f8b676d 249 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 2 240 1.7E-117 T 29-03-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 MC49_RS11165 f65d04b7982954a51b4340a16f8b676d 249 SUPERFAMILY SSF53448 1 246 8.11E-67 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MC49_RS15860 42c7fc6713041730c1fb486a298183e4 355 SUPERFAMILY SSF144064 6 345 3.04E-118 T 29-03-2018 MC49_RS15860 42c7fc6713041730c1fb486a298183e4 355 Gene3D G3DSA:3.40.1570.10 184 355 3.8E-49 T 29-03-2018 MC49_RS15860 42c7fc6713041730c1fb486a298183e4 355 Pfam PF05171 Haemin-degrading HemS.ChuX domain 207 345 1.4E-37 T 29-03-2018 IPR007845 Haemin-degrading HemS/ChuX domain GO:0006826 MC49_RS15860 42c7fc6713041730c1fb486a298183e4 355 Pfam PF05171 Haemin-degrading HemS.ChuX domain 29 157 1.7E-35 T 29-03-2018 IPR007845 Haemin-degrading HemS/ChuX domain GO:0006826 MC49_RS15860 42c7fc6713041730c1fb486a298183e4 355 Gene3D G3DSA:3.40.1570.10 1 183 5.3E-48 T 29-03-2018 MC49_RS06275 9ee30ee46338ab6e5bcc5c43bf8c4432 210 ProSitePatterns PS00042 Crp-type HTH domain signature. 168 191 - T 29-03-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 MC49_RS06275 9ee30ee46338ab6e5bcc5c43bf8c4432 210 ProSitePatterns PS00888 Cyclic nucleotide-binding domain signature 1. 30 46 - T 29-03-2018 IPR018488 Cyclic nucleotide-binding, conserved site MC49_RS06275 9ee30ee46338ab6e5bcc5c43bf8c4432 210 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 71 89 - T 29-03-2018 IPR018488 Cyclic nucleotide-binding, conserved site MC49_RS06275 9ee30ee46338ab6e5bcc5c43bf8c4432 210 Gene3D G3DSA:2.60.120.10 4 144 4.4E-34 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MC49_RS06275 9ee30ee46338ab6e5bcc5c43bf8c4432 210 SUPERFAMILY SSF51206 8 136 4.06E-35 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like MC49_RS06275 9ee30ee46338ab6e5bcc5c43bf8c4432 210 Pfam PF00325 Bacterial regulatory proteins, crp family 166 197 1.8E-15 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MC49_RS06275 9ee30ee46338ab6e5bcc5c43bf8c4432 210 SUPERFAMILY SSF46785 139 207 3.64E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS06275 9ee30ee46338ab6e5bcc5c43bf8c4432 210 SMART SM00100 2 122 1.0E-26 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain MC49_RS06275 9ee30ee46338ab6e5bcc5c43bf8c4432 210 Gene3D G3DSA:1.10.10.10 145 210 9.9E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS06275 9ee30ee46338ab6e5bcc5c43bf8c4432 210 SMART SM00419 160 208 4.5E-17 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MC49_RS06275 9ee30ee46338ab6e5bcc5c43bf8c4432 210 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 166 182 8.8E-11 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MC49_RS06275 9ee30ee46338ab6e5bcc5c43bf8c4432 210 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 182 197 8.8E-11 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MC49_RS06275 9ee30ee46338ab6e5bcc5c43bf8c4432 210 Pfam PF00027 Cyclic nucleotide-binding domain 23 109 1.1E-23 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain MC49_RS06595 fb05c877e9935293d5aabaf89ab797cf 213 SUPERFAMILY SSF51569 5 208 2.93E-69 T 29-03-2018 MC49_RS06595 fb05c877e9935293d5aabaf89ab797cf 213 Gene3D G3DSA:3.20.20.70 6 213 4.9E-28 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS06595 fb05c877e9935293d5aabaf89ab797cf 213 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 128 141 - T 29-03-2018 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 MC49_RS06595 fb05c877e9935293d5aabaf89ab797cf 213 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 9 209 8.0E-83 T 29-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 MC49_RS06595 fb05c877e9935293d5aabaf89ab797cf 213 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 40 49 - T 29-03-2018 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 MC49_RS06595 fb05c877e9935293d5aabaf89ab797cf 213 Pfam PF01081 KDPG and KHG aldolase 10 203 1.6E-84 T 29-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 MC49_RS14215 8a47e6acb37781c2eeb7e59a4cd762dc 233 SUPERFAMILY SSF53067 5 107 5.61E-30 T 29-03-2018 MC49_RS14215 8a47e6acb37781c2eeb7e59a4cd762dc 233 Gene3D G3DSA:3.30.420.40 1 138 7.5E-39 T 29-03-2018 MC49_RS14215 8a47e6acb37781c2eeb7e59a4cd762dc 233 Pfam PF00814 Glycoprotease family 32 152 3.6E-30 T 29-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MC49_RS14215 8a47e6acb37781c2eeb7e59a4cd762dc 233 Gene3D G3DSA:3.30.420.40 139 233 0.0098 T 29-03-2018 MC49_RS14215 8a47e6acb37781c2eeb7e59a4cd762dc 233 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 5 221 2.3E-64 T 29-03-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 MC49_RS14215 8a47e6acb37781c2eeb7e59a4cd762dc 233 SUPERFAMILY SSF53067 112 219 3.37E-25 T 29-03-2018 MC49_RS01090 b3b242f0fe2b81608f835b89fa5efa3f 675 SUPERFAMILY SSF52540 105 558 3.24E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS01090 b3b242f0fe2b81608f835b89fa5efa3f 675 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 112 562 5.0E-104 T 29-03-2018 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 MC49_RS01090 b3b242f0fe2b81608f835b89fa5efa3f 675 Gene3D G3DSA:3.40.50.300 97 561 1.3E-49 T 29-03-2018 MC49_RS18870 7c0f27650156ab466953d3251d32f13c 105 SMART SM00418 18 96 6.7E-27 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MC49_RS18870 7c0f27650156ab466953d3251d32f13c 105 Gene3D G3DSA:1.10.10.10 5 93 2.1E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS18870 7c0f27650156ab466953d3251d32f13c 105 SUPERFAMILY SSF46785 9 99 2.33E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS18870 7c0f27650156ab466953d3251d32f13c 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 6.8E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MC49_RS18870 7c0f27650156ab466953d3251d32f13c 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 67 82 6.8E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MC49_RS18870 7c0f27650156ab466953d3251d32f13c 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 20 35 6.8E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MC49_RS18870 7c0f27650156ab466953d3251d32f13c 105 Pfam PF01022 Bacterial regulatory protein, arsR family 25 70 1.3E-15 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MC49_RS07535 f0559e3379860b9d8d3e732b4c00876b 430 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 98 367 9.7E-23 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MC49_RS07535 f0559e3379860b9d8d3e732b4c00876b 430 Gene3D G3DSA:3.90.1380.10 1 81 2.4E-15 T 29-03-2018 IPR029144 Threonine synthase, N-terminal MC49_RS07535 f0559e3379860b9d8d3e732b4c00876b 430 SUPERFAMILY SSF53686 1 427 1.83E-133 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MC49_RS07535 f0559e3379860b9d8d3e732b4c00876b 430 TIGRFAM TIGR00260 thrC: threonine synthase 54 396 2.1E-114 T 29-03-2018 IPR004450 Threonine synthase-like MC49_RS07535 f0559e3379860b9d8d3e732b4c00876b 430 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 97 111 - T 29-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 MC49_RS07535 f0559e3379860b9d8d3e732b4c00876b 430 Gene3D G3DSA:3.40.50.1100 198 323 2.5E-42 T 29-03-2018 MC49_RS07535 f0559e3379860b9d8d3e732b4c00876b 430 Gene3D G3DSA:3.40.50.1100 324 395 7.1E-14 T 29-03-2018 MC49_RS07535 f0559e3379860b9d8d3e732b4c00876b 430 Gene3D G3DSA:3.40.50.1100 101 197 8.9E-20 T 29-03-2018 MC49_RS07535 f0559e3379860b9d8d3e732b4c00876b 430 Pfam PF14821 Threonine synthase N terminus 8 80 5.5E-11 T 29-03-2018 IPR029144 Threonine synthase, N-terminal MC49_RS09465 dc78d9d6fc82e5b7f91c5474b8db6cfe 1514 SUPERFAMILY SSF69318 461 549 2.44E-11 T 29-03-2018 MC49_RS09465 dc78d9d6fc82e5b7f91c5474b8db6cfe 1514 SUPERFAMILY SSF69318 590 677 2.44E-11 T 29-03-2018 MC49_RS09465 dc78d9d6fc82e5b7f91c5474b8db6cfe 1514 Pfam PF12256 Insecticide toxin TcdB middle/N-terminal region 687 833 2.9E-14 T 29-03-2018 IPR022045 Insecticide toxin TcdB middle/N-terminal MC49_RS09465 dc78d9d6fc82e5b7f91c5474b8db6cfe 1514 PRINTS PR01341 Salmonella virulence plasmid 65kDa B protein signature 214 232 4.8E-26 T 29-03-2018 IPR003284 Salmonella virulence plasmid 65kDa B protein GO:0005737 MC49_RS09465 dc78d9d6fc82e5b7f91c5474b8db6cfe 1514 PRINTS PR01341 Salmonella virulence plasmid 65kDa B protein signature 287 306 4.8E-26 T 29-03-2018 IPR003284 Salmonella virulence plasmid 65kDa B protein GO:0005737 MC49_RS09465 dc78d9d6fc82e5b7f91c5474b8db6cfe 1514 PRINTS PR01341 Salmonella virulence plasmid 65kDa B protein signature 109 125 4.8E-26 T 29-03-2018 IPR003284 Salmonella virulence plasmid 65kDa B protein GO:0005737 MC49_RS09465 dc78d9d6fc82e5b7f91c5474b8db6cfe 1514 PRINTS PR01341 Salmonella virulence plasmid 65kDa B protein signature 50 71 4.8E-26 T 29-03-2018 IPR003284 Salmonella virulence plasmid 65kDa B protein GO:0005737 MC49_RS09465 dc78d9d6fc82e5b7f91c5474b8db6cfe 1514 PRINTS PR01341 Salmonella virulence plasmid 65kDa B protein signature 322 340 4.8E-26 T 29-03-2018 IPR003284 Salmonella virulence plasmid 65kDa B protein GO:0005737 MC49_RS09465 dc78d9d6fc82e5b7f91c5474b8db6cfe 1514 PRINTS PR01341 Salmonella virulence plasmid 65kDa B protein signature 150 168 4.8E-26 T 29-03-2018 IPR003284 Salmonella virulence plasmid 65kDa B protein GO:0005737 MC49_RS09465 dc78d9d6fc82e5b7f91c5474b8db6cfe 1514 Pfam PF03534 Salmonella virulence plasmid 65kDa B protein 53 340 4.1E-85 T 29-03-2018 IPR003284 Salmonella virulence plasmid 65kDa B protein GO:0005737 MC49_RS09465 dc78d9d6fc82e5b7f91c5474b8db6cfe 1514 Pfam PF12255 Insecticide toxin TcdB middle/C-terminal region 875 1011 1.1E-38 T 29-03-2018 IPR022044 Insecticide toxin TcdB middle/C-terminal MC49_RS09465 dc78d9d6fc82e5b7f91c5474b8db6cfe 1514 Gene3D G3DSA:2.130.10.130 418 702 4.9E-8 T 29-03-2018 MC49_RS02550 156bba16b8e221e9593a7e644eb3685a 424 Gene3D G3DSA:3.40.50.1110 66 423 1.3E-38 T 29-03-2018 MC49_RS02550 156bba16b8e221e9593a7e644eb3685a 424 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 261 407 1.0E-11 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain MC49_RS02550 156bba16b8e221e9593a7e644eb3685a 424 SUPERFAMILY SSF52266 260 422 9.92E-28 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain MC49_RS02550 156bba16b8e221e9593a7e644eb3685a 424 SUPERFAMILY SSF52266 90 125 9.92E-28 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain MC49_RS06185 fc91cb456d1b2c8bd1af62d4abfae7af 450 Gene3D G3DSA:3.40.50.720 162 331 2.6E-35 T 29-03-2018 MC49_RS06185 fc91cb456d1b2c8bd1af62d4abfae7af 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 270 1.0E-29 T 29-03-2018 MC49_RS06185 fc91cb456d1b2c8bd1af62d4abfae7af 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.0E-29 T 29-03-2018 MC49_RS06185 fc91cb456d1b2c8bd1af62d4abfae7af 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 150 1.0E-29 T 29-03-2018 MC49_RS06185 fc91cb456d1b2c8bd1af62d4abfae7af 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 1.0E-29 T 29-03-2018 MC49_RS06185 fc91cb456d1b2c8bd1af62d4abfae7af 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 283 305 1.0E-29 T 29-03-2018 MC49_RS06185 fc91cb456d1b2c8bd1af62d4abfae7af 450 PIRSF PIRSF000350 1 447 5.0E-85 T 29-03-2018 MC49_RS06185 fc91cb456d1b2c8bd1af62d4abfae7af 450 TIGRFAM TIGR01421 gluta_reduc_1: glutathione-disulfide reductase 3 450 4.4E-216 T 29-03-2018 IPR006322 Glutathione reductase, eukaryote/bacterial GO:0004362|GO:0006749|GO:0050660|GO:0050661|GO:0055114 KEGG: 00480+1.8.1.7|MetaCyc: PWY-4081|Reactome: R-HSA-2408550|Reactome: R-HSA-3299685|Reactome: R-HSA-499943|Reactome: R-HSA-5628897 MC49_RS06185 fc91cb456d1b2c8bd1af62d4abfae7af 450 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 318 2.3E-68 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS06185 fc91cb456d1b2c8bd1af62d4abfae7af 450 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 339 449 7.1E-36 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MC49_RS06185 fc91cb456d1b2c8bd1af62d4abfae7af 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 135 144 1.4E-66 T 29-03-2018 MC49_RS06185 fc91cb456d1b2c8bd1af62d4abfae7af 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 402 417 1.4E-66 T 29-03-2018 MC49_RS06185 fc91cb456d1b2c8bd1af62d4abfae7af 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 255 269 1.4E-66 T 29-03-2018 MC49_RS06185 fc91cb456d1b2c8bd1af62d4abfae7af 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 424 444 1.4E-66 T 29-03-2018 MC49_RS06185 fc91cb456d1b2c8bd1af62d4abfae7af 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 298 305 1.4E-66 T 29-03-2018 MC49_RS06185 fc91cb456d1b2c8bd1af62d4abfae7af 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 335 356 1.4E-66 T 29-03-2018 MC49_RS06185 fc91cb456d1b2c8bd1af62d4abfae7af 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 1.4E-66 T 29-03-2018 MC49_RS06185 fc91cb456d1b2c8bd1af62d4abfae7af 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 1.4E-66 T 29-03-2018 MC49_RS06185 fc91cb456d1b2c8bd1af62d4abfae7af 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 169 194 1.4E-66 T 29-03-2018 MC49_RS06185 fc91cb456d1b2c8bd1af62d4abfae7af 450 SUPERFAMILY SSF51905 3 369 1.08E-54 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS06185 fc91cb456d1b2c8bd1af62d4abfae7af 450 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 MC49_RS06185 fc91cb456d1b2c8bd1af62d4abfae7af 450 Gene3D G3DSA:3.50.50.60 1 161 2.1E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS06185 fc91cb456d1b2c8bd1af62d4abfae7af 450 Gene3D G3DSA:3.30.390.30 332 450 6.0E-39 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 MC49_RS06185 fc91cb456d1b2c8bd1af62d4abfae7af 450 SUPERFAMILY SSF55424 336 450 1.53E-36 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 MC49_RS12605 606874cc23752d65b39c85a4c9077dd4 337 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 5 323 1.9E-107 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 MC49_RS12605 606874cc23752d65b39c85a4c9077dd4 337 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 255 323 5.0E-16 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) MC49_RS12605 606874cc23752d65b39c85a4c9077dd4 337 SUPERFAMILY SSF101801 252 325 2.62E-12 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) MC49_RS12605 606874cc23752d65b39c85a4c9077dd4 337 PRINTS PR00955 Flagellar motor switch protein FliM signature 116 135 7.6E-29 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 MC49_RS12605 606874cc23752d65b39c85a4c9077dd4 337 PRINTS PR00955 Flagellar motor switch protein FliM signature 91 107 7.6E-29 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 MC49_RS12605 606874cc23752d65b39c85a4c9077dd4 337 PRINTS PR00955 Flagellar motor switch protein FliM signature 3 16 7.6E-29 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 MC49_RS12605 606874cc23752d65b39c85a4c9077dd4 337 PRINTS PR00955 Flagellar motor switch protein FliM signature 215 233 7.6E-29 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 MC49_RS12605 606874cc23752d65b39c85a4c9077dd4 337 Gene3D G3DSA:2.30.330.10 241 331 3.6E-14 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) MC49_RS12605 606874cc23752d65b39c85a4c9077dd4 337 Pfam PF02154 Flagellar motor switch protein FliM 40 233 4.9E-74 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 MC49_RS12605 606874cc23752d65b39c85a4c9077dd4 337 Gene3D G3DSA:3.40.1550.10 48 236 6.5E-36 T 29-03-2018 IPR028976 CheC-like domain MC49_RS12605 606874cc23752d65b39c85a4c9077dd4 337 PIRSF PIRSF002888 2 333 6.2E-95 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 MC49_RS12605 606874cc23752d65b39c85a4c9077dd4 337 SUPERFAMILY SSF103039 52 233 1.31E-18 T 29-03-2018 IPR028976 CheC-like domain MC49_RS05110 e7c554608b227dd4d26185fb2c0e186b 484 Pfam PF05762 VWA domain containing CoxE-like protein 306 459 4.7E-11 T 29-03-2018 IPR008912 Uncharacterised protein family CoxE-like MC49_RS05110 e7c554608b227dd4d26185fb2c0e186b 484 SMART SM00327 320 484 1.0E-9 T 29-03-2018 IPR002035 von Willebrand factor, type A MC49_RS05110 e7c554608b227dd4d26185fb2c0e186b 484 SUPERFAMILY SSF53300 319 460 5.93E-17 T 29-03-2018 IPR002035 von Willebrand factor, type A MC49_RS05110 e7c554608b227dd4d26185fb2c0e186b 484 Hamap MF_01626 Protein ViaA [viaA]. 1 484 49.917 T 29-03-2018 IPR023481 Uncharacterised protein family ViaA MC49_RS05110 e7c554608b227dd4d26185fb2c0e186b 484 Gene3D G3DSA:3.40.50.410 298 465 1.2E-19 T 29-03-2018 IPR002035 von Willebrand factor, type A MC49_RS10405 bfa7abcddcbb6099ac1bba3e9361c95a 380 PIRSF PIRSF000267 2 379 1.4E-128 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MC49_RS10405 bfa7abcddcbb6099ac1bba3e9361c95a 380 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 1 380 1.9E-182 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MC49_RS10405 bfa7abcddcbb6099ac1bba3e9361c95a 380 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 7 362 3.2E-107 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MC49_RS02070 0e97fce78871c7de6667243b63083422 557 Pfam PF08019 Domain of unknown function (DUF1705) 64 224 7.8E-17 T 29-03-2018 IPR012549 Phosphoethanolamine transferase, N-terminal GO:0016021 MC49_RS02070 0e97fce78871c7de6667243b63083422 557 SUPERFAMILY SSF53649 254 544 4.74E-22 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MC49_RS02070 0e97fce78871c7de6667243b63083422 557 Pfam PF00884 Sulfatase 254 540 3.1E-44 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 MC49_RS02070 0e97fce78871c7de6667243b63083422 557 Gene3D G3DSA:3.40.720.10 246 546 1.4E-23 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 MC49_RS08865 bbcd5865887cf6f1560738d90b3b371c 353 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 40 216 3.8E-49 T 29-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain MC49_RS08865 bbcd5865887cf6f1560738d90b3b371c 353 Gene3D G3DSA:3.40.50.300 35 236 1.8E-44 T 29-03-2018 MC49_RS08865 bbcd5865887cf6f1560738d90b3b371c 353 SUPERFAMILY SSF90002 258 350 2.22E-22 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal MC49_RS08865 bbcd5865887cf6f1560738d90b3b371c 353 SMART SM00833 258 352 1.0E-9 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal MC49_RS08865 bbcd5865887cf6f1560738d90b3b371c 353 Gene3D G3DSA:3.30.1220.10 249 353 3.3E-19 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal MC49_RS08865 bbcd5865887cf6f1560738d90b3b371c 353 SUPERFAMILY SSF52540 36 219 2.81E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS08865 bbcd5865887cf6f1560738d90b3b371c 353 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 258 350 2.0E-17 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal MC49_RS08030 2aec3af979138fc71636ad70dd8905cb 239 PRINTS PR00395 Ribosomal protein S2 signature 196 210 5.5E-38 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS08030 2aec3af979138fc71636ad70dd8905cb 239 PRINTS PR00395 Ribosomal protein S2 signature 158 175 5.5E-38 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS08030 2aec3af979138fc71636ad70dd8905cb 239 PRINTS PR00395 Ribosomal protein S2 signature 87 104 5.5E-38 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS08030 2aec3af979138fc71636ad70dd8905cb 239 PRINTS PR00395 Ribosomal protein S2 signature 6 24 5.5E-38 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS08030 2aec3af979138fc71636ad70dd8905cb 239 PRINTS PR00395 Ribosomal protein S2 signature 175 186 5.5E-38 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS08030 2aec3af979138fc71636ad70dd8905cb 239 PRINTS PR00395 Ribosomal protein S2 signature 37 46 5.5E-38 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS08030 2aec3af979138fc71636ad70dd8905cb 239 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 29-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 MC49_RS08030 2aec3af979138fc71636ad70dd8905cb 239 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 29-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 MC49_RS08030 2aec3af979138fc71636ad70dd8905cb 239 SUPERFAMILY SSF52313 6 234 8.63E-96 T 29-03-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain MC49_RS08030 2aec3af979138fc71636ad70dd8905cb 239 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 226 2.9E-108 T 29-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS08030 2aec3af979138fc71636ad70dd8905cb 239 Pfam PF00318 Ribosomal protein S2 9 224 5.8E-94 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS08030 2aec3af979138fc71636ad70dd8905cb 239 Gene3D G3DSA:3.40.50.10490 5 239 9.6E-96 T 29-03-2018 MC49_RS08030 2aec3af979138fc71636ad70dd8905cb 239 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 225 41.486 T 29-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS03740 d49370d0317b16eac336a612964c8530 313 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 226 295 1.7E-20 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MC49_RS03740 d49370d0317b16eac336a612964c8530 313 Gene3D G3DSA:3.40.190.10 1 106 1.6E-44 T 29-03-2018 MC49_RS03740 d49370d0317b16eac336a612964c8530 313 Gene3D G3DSA:3.40.190.10 107 199 4.8E-37 T 29-03-2018 MC49_RS03740 d49370d0317b16eac336a612964c8530 313 Gene3D G3DSA:3.30.160.40 221 306 2.5E-24 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MC49_RS03740 d49370d0317b16eac336a612964c8530 313 SUPERFAMILY SSF53850 5 218 8.25E-84 T 29-03-2018 MC49_RS03740 d49370d0317b16eac336a612964c8530 313 PRINTS PR00151 Porphobilinogen deaminase signature 76 95 3.8E-49 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MC49_RS03740 d49370d0317b16eac336a612964c8530 313 PRINTS PR00151 Porphobilinogen deaminase signature 230 247 3.8E-49 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MC49_RS03740 d49370d0317b16eac336a612964c8530 313 PRINTS PR00151 Porphobilinogen deaminase signature 45 65 3.8E-49 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MC49_RS03740 d49370d0317b16eac336a612964c8530 313 PRINTS PR00151 Porphobilinogen deaminase signature 124 141 3.8E-49 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MC49_RS03740 d49370d0317b16eac336a612964c8530 313 PRINTS PR00151 Porphobilinogen deaminase signature 143 160 3.8E-49 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MC49_RS03740 d49370d0317b16eac336a612964c8530 313 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 231 247 - T 29-03-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MC49_RS03740 d49370d0317b16eac336a612964c8530 313 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 5 297 39.319 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MC49_RS03740 d49370d0317b16eac336a612964c8530 313 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 6 213 3.1E-78 T 29-03-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MC49_RS03740 d49370d0317b16eac336a612964c8530 313 SUPERFAMILY SSF54782 220 309 3.79E-28 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MC49_RS03740 d49370d0317b16eac336a612964c8530 313 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 6 297 4.4E-110 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MC49_RS03740 d49370d0317b16eac336a612964c8530 313 PIRSF PIRSF001438 1 311 6.3E-122 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MC49_RS10165 b89822e26aee5d794238fe9cd6e6db34 225 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 118 5.4E-23 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 MC49_RS10165 b89822e26aee5d794238fe9cd6e6db34 225 Gene3D G3DSA:1.10.3720.10 2 225 1.3E-39 T 29-03-2018 MC49_RS10165 b89822e26aee5d794238fe9cd6e6db34 225 SUPERFAMILY SSF161098 14 209 1.1E-38 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS10165 b89822e26aee5d794238fe9cd6e6db34 225 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 223 2.0E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS04300 6c463049188f04eceb9c57e2b4c062d9 245 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 18 84 6.1E-17 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 MC49_RS04300 6c463049188f04eceb9c57e2b4c062d9 245 Gene3D G3DSA:1.10.3720.10 13 242 2.6E-41 T 29-03-2018 MC49_RS04300 6c463049188f04eceb9c57e2b4c062d9 245 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 54 235 6.4E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS04300 6c463049188f04eceb9c57e2b4c062d9 245 SUPERFAMILY SSF161098 18 226 8.5E-39 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS04940 8656392157db10f3f68e8e35c5a425ff 490 Pfam PF12161 HsdM N-terminal domain 4 130 2.0E-15 T 29-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain MC49_RS04940 8656392157db10f3f68e8e35c5a425ff 490 Pfam PF02384 N-6 DNA Methylase 140 452 8.9E-97 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 MC49_RS04940 8656392157db10f3f68e8e35c5a425ff 490 Gene3D G3DSA:3.40.50.150 160 446 5.0E-60 T 29-03-2018 MC49_RS04940 8656392157db10f3f68e8e35c5a425ff 490 SUPERFAMILY SSF53335 3 481 1.22E-125 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS04940 8656392157db10f3f68e8e35c5a425ff 490 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 270 276 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MC49_RS04940 8656392157db10f3f68e8e35c5a425ff 490 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 186 200 4.8E-22 T 29-03-2018 MC49_RS04940 8656392157db10f3f68e8e35c5a425ff 490 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 162 178 4.8E-22 T 29-03-2018 MC49_RS04940 8656392157db10f3f68e8e35c5a425ff 490 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 296 320 4.8E-22 T 29-03-2018 MC49_RS04940 8656392157db10f3f68e8e35c5a425ff 490 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 267 279 4.8E-22 T 29-03-2018 MC49_RS18735 5be213cf7224ca5320ec8638f49ecf1c 363 Gene3D G3DSA:3.40.718.10 1 363 3.2E-130 T 29-03-2018 MC49_RS18735 5be213cf7224ca5320ec8638f49ecf1c 363 SUPERFAMILY SSF53659 3 360 2.7E-123 T 29-03-2018 MC49_RS18735 5be213cf7224ca5320ec8638f49ecf1c 363 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 5 359 51.001 T 29-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 MC49_RS18735 5be213cf7224ca5320ec8638f49ecf1c 363 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 247 266 - T 29-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 MC49_RS18735 5be213cf7224ca5320ec8638f49ecf1c 363 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 6 355 2.5E-137 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MC49_RS18735 5be213cf7224ca5320ec8638f49ecf1c 363 SMART SM01329 6 355 4.5E-202 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MC49_RS18735 5be213cf7224ca5320ec8638f49ecf1c 363 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 6 354 4.9E-166 T 29-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 MC49_RS01280 fece9ece2a8e43630189314c30b31dd7 1971 Pfam PF11974 Alpha-2-macroglobulin MG1 domain 601 704 8.1E-20 T 29-03-2018 MC49_RS01280 fece9ece2a8e43630189314c30b31dd7 1971 Gene3D G3DSA:2.60.40.10 1840 1959 0.15 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS01280 fece9ece2a8e43630189314c30b31dd7 1971 Gene3D G3DSA:2.60.40.10 1334 1447 1.0E-9 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS01280 fece9ece2a8e43630189314c30b31dd7 1971 Gene3D G3DSA:1.50.10.20 1477 1839 5.7E-17 T 29-03-2018 MC49_RS01280 fece9ece2a8e43630189314c30b31dd7 1971 Pfam PF07703 Alpha-2-macroglobulin family N-terminal region 1079 1217 7.8E-10 T 29-03-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 MC49_RS01280 fece9ece2a8e43630189314c30b31dd7 1971 Pfam PF01835 MG2 domain 715 800 3.8E-16 T 29-03-2018 IPR002890 Alpha-2-macroglobulin, N-terminal GO:0004866 MC49_RS01280 fece9ece2a8e43630189314c30b31dd7 1971 SMART SM01360 1284 1376 3.7E-20 T 29-03-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 MC49_RS01280 fece9ece2a8e43630189314c30b31dd7 1971 Gene3D G3DSA:2.60.40.10 712 813 0.0021 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS01280 fece9ece2a8e43630189314c30b31dd7 1971 Gene3D G3DSA:2.60.40.10 1016 1333 0.081 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS01280 fece9ece2a8e43630189314c30b31dd7 1971 SUPERFAMILY SSF48239 1488 1747 4.45E-17 T 29-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid MC49_RS01280 fece9ece2a8e43630189314c30b31dd7 1971 Pfam PF00207 Alpha-2-macroglobulin family 1285 1362 8.5E-12 T 29-03-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 MC49_RS01280 fece9ece2a8e43630189314c30b31dd7 1971 SMART SM01359 1079 1218 6.7E-32 T 29-03-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 MC49_RS01280 fece9ece2a8e43630189314c30b31dd7 1971 Gene3D G3DSA:2.60.40.10 613 704 0.012 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS01610 557a69590b422549324c5a95aff3011b 136 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 50 126 3.3E-18 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 MC49_RS01610 557a69590b422549324c5a95aff3011b 136 PIRSF PIRSF006092 22 128 7.7E-24 T 29-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 MC49_RS01610 557a69590b422549324c5a95aff3011b 136 Gene3D G3DSA:1.10.286.20 3 43 7.2E-15 T 29-03-2018 MC49_RS01610 557a69590b422549324c5a95aff3011b 136 Hamap MF_00954 Regulator of nucleoside diphosphate kinase [rnk]. 1 136 42.569 T 29-03-2018 IPR028625 Regulator of nucleoside diphosphate kinase GO:0065007|GO:0070063 MC49_RS01610 557a69590b422549324c5a95aff3011b 136 SUPERFAMILY SSF54534 49 127 1.22E-17 T 29-03-2018 MC49_RS01610 557a69590b422549324c5a95aff3011b 136 Gene3D G3DSA:3.10.50.30 45 136 5.2E-22 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 MC49_RS01610 557a69590b422549324c5a95aff3011b 136 Pfam PF14760 Rnk N-terminus 4 43 2.5E-13 T 29-03-2018 IPR029462 Regulator of nucleoside diphosphate kinase, N-terminal domain MC49_RS15170 7dc1eccf3866d2815bc224a72d6adc55 396 Gene3D G3DSA:3.40.50.1100 8 193 1.7E-44 T 29-03-2018 MC49_RS15170 7dc1eccf3866d2815bc224a72d6adc55 396 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 7 388 7.7E-189 T 29-03-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MC49_RS15170 7dc1eccf3866d2815bc224a72d6adc55 396 Gene3D G3DSA:3.40.50.1100 194 395 3.4E-36 T 29-03-2018 MC49_RS15170 7dc1eccf3866d2815bc224a72d6adc55 396 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 1 390 49.212 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MC49_RS15170 7dc1eccf3866d2815bc224a72d6adc55 396 PIRSF PIRSF001413 1 395 1.8E-166 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MC49_RS15170 7dc1eccf3866d2815bc224a72d6adc55 396 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 51 373 3.3E-46 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MC49_RS15170 7dc1eccf3866d2815bc224a72d6adc55 396 SUPERFAMILY SSF53686 4 389 4.45E-141 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MC49_RS15170 7dc1eccf3866d2815bc224a72d6adc55 396 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 79 93 - T 29-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MC49_RS14855 02d66f7a91eadaa91536e0943d3835fa 396 SUPERFAMILY SSF103473 3 387 1.44E-31 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS14855 02d66f7a91eadaa91536e0943d3835fa 396 Gene3D G3DSA:1.20.1250.20 197 388 1.9E-15 T 29-03-2018 MC49_RS14855 02d66f7a91eadaa91536e0943d3835fa 396 Gene3D G3DSA:1.20.1250.20 2 196 4.0E-12 T 29-03-2018 MC49_RS14855 02d66f7a91eadaa91536e0943d3835fa 396 Pfam PF07690 Major Facilitator Superfamily 8 340 2.7E-18 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS15430 90a4e5bc620353d2cfae58949b18b100 137 SUPERFAMILY SSF51316 8 130 1.46E-55 T 29-03-2018 IPR011057 Mss4-like MC49_RS15430 90a4e5bc620353d2cfae58949b18b100 137 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 10 130 4.2E-56 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 MC49_RS15430 90a4e5bc620353d2cfae58949b18b100 137 Pfam PF01641 SelR domain 12 127 3.4E-51 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 MC49_RS15430 90a4e5bc620353d2cfae58949b18b100 137 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 4 129 37.676 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 MC49_RS15430 90a4e5bc620353d2cfae58949b18b100 137 Gene3D G3DSA:2.170.150.20 3 136 2.4E-56 T 29-03-2018 MC49_RS13840 3087b5740c1087bcbcaeb47e1324a035 316 Gene3D G3DSA:1.10.3470.10 8 315 8.3E-24 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like MC49_RS13840 3087b5740c1087bcbcaeb47e1324a035 316 Pfam PF02653 Branched-chain amino acid transport system / permease component 42 308 1.1E-35 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 MC49_RS10770 2c8827638105eed97702248a6837087e 565 PRINTS PR00072 Malic enzyme signature 408 424 2.1E-72 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MC49_RS10770 2c8827638105eed97702248a6837087e 565 PRINTS PR00072 Malic enzyme signature 242 260 2.1E-72 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MC49_RS10770 2c8827638105eed97702248a6837087e 565 PRINTS PR00072 Malic enzyme signature 87 111 2.1E-72 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MC49_RS10770 2c8827638105eed97702248a6837087e 565 PRINTS PR00072 Malic enzyme signature 183 205 2.1E-72 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MC49_RS10770 2c8827638105eed97702248a6837087e 565 PRINTS PR00072 Malic enzyme signature 147 176 2.1E-72 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MC49_RS10770 2c8827638105eed97702248a6837087e 565 PRINTS PR00072 Malic enzyme signature 267 283 2.1E-72 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MC49_RS10770 2c8827638105eed97702248a6837087e 565 PRINTS PR00072 Malic enzyme signature 298 314 2.1E-72 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MC49_RS10770 2c8827638105eed97702248a6837087e 565 Pfam PF00390 Malic enzyme, N-terminal domain 81 261 1.3E-79 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MC49_RS10770 2c8827638105eed97702248a6837087e 565 ProSitePatterns PS00331 Malic enzymes signature. 267 283 - T 29-03-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 MC49_RS10770 2c8827638105eed97702248a6837087e 565 Gene3D G3DSA:3.40.50.720 269 564 1.8E-105 T 29-03-2018 MC49_RS10770 2c8827638105eed97702248a6837087e 565 Gene3D G3DSA:3.40.50.10380 15 268 6.8E-116 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MC49_RS10770 2c8827638105eed97702248a6837087e 565 SUPERFAMILY SSF51735 271 562 1.07E-93 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS10770 2c8827638105eed97702248a6837087e 565 Hamap MF_01619 NAD-dependent malic enzyme [maeA]. 4 565 71.069 T 29-03-2018 IPR023667 NAD-dependent malic enzyme, proteobacteria GO:0004471|GO:0055114 KEGG: 00620+1.1.1.38 MC49_RS10770 2c8827638105eed97702248a6837087e 565 Pfam PF03949 Malic enzyme, NAD binding domain 271 530 9.1E-101 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 MC49_RS10770 2c8827638105eed97702248a6837087e 565 PIRSF PIRSF000106 2 563 1.9E-228 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MC49_RS10770 2c8827638105eed97702248a6837087e 565 SMART SM01274 81 261 1.4E-108 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MC49_RS10770 2c8827638105eed97702248a6837087e 565 SMART SM00919 271 531 1.8E-132 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 MC49_RS10770 2c8827638105eed97702248a6837087e 565 SUPERFAMILY SSF53223 6 270 7.91E-111 T 29-03-2018 MC49_RS08825 47496d707346871f9f5d4f4de401fceb 1251 Gene3D G3DSA:1.20.5.1000 921 976 2.2E-6 T 29-03-2018 MC49_RS08825 47496d707346871f9f5d4f4de401fceb 1251 Gene3D G3DSA:1.20.5.1000 1065 1138 0.0089 T 29-03-2018 MC49_RS08825 47496d707346871f9f5d4f4de401fceb 1251 Gene3D G3DSA:1.20.120.330 697 816 2.3E-4 T 29-03-2018 MC49_RS08825 47496d707346871f9f5d4f4de401fceb 1251 SUPERFAMILY SSF54534 1072 1250 9.82E-12 T 29-03-2018 MC49_RS08825 47496d707346871f9f5d4f4de401fceb 1251 Gene3D G3DSA:1.20.5.50 527 599 0.0036 T 29-03-2018 MC49_RS08825 47496d707346871f9f5d4f4de401fceb 1251 Gene3D G3DSA:1.20.5.50 433 526 1.1E-6 T 29-03-2018 MC49_RS08825 47496d707346871f9f5d4f4de401fceb 1251 Gene3D G3DSA:1.20.5.50 214 340 3.1E-6 T 29-03-2018 MC49_RS08825 47496d707346871f9f5d4f4de401fceb 1251 Gene3D G3DSA:1.20.5.50 600 696 0.0036 T 29-03-2018 MC49_RS08825 47496d707346871f9f5d4f4de401fceb 1251 Gene3D G3DSA:1.20.5.400 346 430 8.7E-5 T 29-03-2018 MC49_RS08825 47496d707346871f9f5d4f4de401fceb 1251 Gene3D G3DSA:1.20.5.730 977 1042 0.023 T 29-03-2018 MC49_RS08825 47496d707346871f9f5d4f4de401fceb 1251 Gene3D G3DSA:1.10.287.510 817 920 0.0016 T 29-03-2018 MC49_RS08825 47496d707346871f9f5d4f4de401fceb 1251 Gene3D G3DSA:3.10.50.40 1139 1251 5.0E-8 T 29-03-2018 MC49_RS17060 67389c3b1f2ce6b85759e9299c4761b4 259 Pfam PF01026 TatD related DNase 4 255 1.6E-79 T 29-03-2018 IPR001130 TatD family GO:0016788 MC49_RS17060 67389c3b1f2ce6b85759e9299c4761b4 259 PIRSF PIRSF005902 1 259 1.3E-79 T 29-03-2018 IPR001130 TatD family GO:0016788 MC49_RS17060 67389c3b1f2ce6b85759e9299c4761b4 259 Gene3D G3DSA:3.20.20.140 1 259 1.0E-82 T 29-03-2018 MC49_RS17060 67389c3b1f2ce6b85759e9299c4761b4 259 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 3 255 8.3E-96 T 29-03-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 MC49_RS17060 67389c3b1f2ce6b85759e9299c4761b4 259 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 126 136 - T 29-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 MC49_RS17060 67389c3b1f2ce6b85759e9299c4761b4 259 SUPERFAMILY SSF51556 1 257 5.26E-89 T 29-03-2018 IPR032466 Metal-dependent hydrolase MC49_RS17060 67389c3b1f2ce6b85759e9299c4761b4 259 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 191 207 - T 29-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 MC49_RS17060 67389c3b1f2ce6b85759e9299c4761b4 259 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 3 11 - T 29-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 MC49_RS14745 7c60f1c6b63ecfcdb3f5c52b6b20a43a 473 Gene3D G3DSA:1.20.1250.20 1 190 3.3E-25 T 29-03-2018 MC49_RS14745 7c60f1c6b63ecfcdb3f5c52b6b20a43a 473 SUPERFAMILY SSF103473 4 197 1.07E-51 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS14745 7c60f1c6b63ecfcdb3f5c52b6b20a43a 473 SUPERFAMILY SSF103473 248 465 1.07E-51 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS14745 7c60f1c6b63ecfcdb3f5c52b6b20a43a 473 Gene3D G3DSA:1.20.1250.20 252 471 1.7E-15 T 29-03-2018 MC49_RS14745 7c60f1c6b63ecfcdb3f5c52b6b20a43a 473 Pfam PF07690 Major Facilitator Superfamily 12 407 1.8E-33 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS04205 4b03650225362f2a7f4dca2fe6b87bfd 314 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 88 241 2.1E-14 T 29-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 MC49_RS04205 4b03650225362f2a7f4dca2fe6b87bfd 314 Hamap MF_00215 Pantothenate kinase [coaA]. 1 314 183.229 T 29-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 MC49_RS04205 4b03650225362f2a7f4dca2fe6b87bfd 314 SUPERFAMILY SSF52540 7 313 7.4E-77 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS04205 4b03650225362f2a7f4dca2fe6b87bfd 314 PIRSF PIRSF000545 1 314 1.3E-146 T 29-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 MC49_RS04205 4b03650225362f2a7f4dca2fe6b87bfd 314 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 9 314 4.6E-161 T 29-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 MC49_RS04205 4b03650225362f2a7f4dca2fe6b87bfd 314 Gene3D G3DSA:3.40.50.300 7 314 9.0E-54 T 29-03-2018 MC49_RS05840 9a661a2b1fc76350b87953db65316987 272 SUPERFAMILY SSF81338 9 259 2.62E-78 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 MC49_RS05840 9a661a2b1fc76350b87953db65316987 272 TIGRFAM TIGR00861 MIP: MIP family channel proteins 15 253 2.4E-70 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 MC49_RS05840 9a661a2b1fc76350b87953db65316987 272 ProSitePatterns PS00221 MIP family signature. 68 76 - T 29-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 MC49_RS05840 9a661a2b1fc76350b87953db65316987 272 Pfam PF00230 Major intrinsic protein 5 253 2.1E-67 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 MC49_RS05840 9a661a2b1fc76350b87953db65316987 272 PRINTS PR00783 Major intrinsic protein family signature 153 171 2.4E-49 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 MC49_RS05840 9a661a2b1fc76350b87953db65316987 272 PRINTS PR00783 Major intrinsic protein family signature 11 30 2.4E-49 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 MC49_RS05840 9a661a2b1fc76350b87953db65316987 272 PRINTS PR00783 Major intrinsic protein family signature 87 106 2.4E-49 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 MC49_RS05840 9a661a2b1fc76350b87953db65316987 272 PRINTS PR00783 Major intrinsic protein family signature 186 208 2.4E-49 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 MC49_RS05840 9a661a2b1fc76350b87953db65316987 272 PRINTS PR00783 Major intrinsic protein family signature 50 74 2.4E-49 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 MC49_RS05840 9a661a2b1fc76350b87953db65316987 272 PRINTS PR00783 Major intrinsic protein family signature 236 256 2.4E-49 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 MC49_RS05840 9a661a2b1fc76350b87953db65316987 272 Gene3D G3DSA:1.20.1080.10 3 261 1.0E-79 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 MC49_RS04480 38a64ac2a825cd7f901c06e980ca238f 548 Pfam PF00158 Sigma-54 interaction domain 209 376 7.0E-67 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MC49_RS04480 38a64ac2a825cd7f901c06e980ca238f 548 SMART SM00091 82 147 7.5E-5 T 29-03-2018 IPR000014 PAS domain MC49_RS04480 38a64ac2a825cd7f901c06e980ca238f 548 Gene3D G3DSA:3.30.450.20 67 199 1.1E-13 T 29-03-2018 MC49_RS04480 38a64ac2a825cd7f901c06e980ca238f 548 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 233 246 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MC49_RS04480 38a64ac2a825cd7f901c06e980ca238f 548 SUPERFAMILY SSF46689 476 532 2.09E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS04480 38a64ac2a825cd7f901c06e980ca238f 548 SMART SM00382 229 373 2.3E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS04480 38a64ac2a825cd7f901c06e980ca238f 548 SUPERFAMILY SSF55785 78 185 8.57E-15 T 29-03-2018 IPR000014 PAS domain MC49_RS04480 38a64ac2a825cd7f901c06e980ca238f 548 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 79 148 2.1E-8 T 29-03-2018 IPR000014 PAS domain MC49_RS04480 38a64ac2a825cd7f901c06e980ca238f 548 Gene3D G3DSA:1.10.10.60 479 533 9.6E-8 T 29-03-2018 MC49_RS04480 38a64ac2a825cd7f901c06e980ca238f 548 SUPERFAMILY SSF52540 208 450 5.44E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS04480 38a64ac2a825cd7f901c06e980ca238f 548 Gene3D G3DSA:1.10.8.60 383 452 7.3E-23 T 29-03-2018 MC49_RS04480 38a64ac2a825cd7f901c06e980ca238f 548 TIGRFAM TIGR04381 HTH_TypR: TyrR family helix-turn-helix domain 486 532 5.5E-9 T 29-03-2018 IPR030828 TyrR family, helix-turn-helix domain GO:0003677 MC49_RS04480 38a64ac2a825cd7f901c06e980ca238f 548 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 422 431 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site MC49_RS04480 38a64ac2a825cd7f901c06e980ca238f 548 Pfam PF00989 PAS fold 83 185 4.1E-11 T 29-03-2018 IPR013767 PAS fold GO:0006355 MC49_RS04480 38a64ac2a825cd7f901c06e980ca238f 548 Gene3D G3DSA:3.40.50.300 204 382 3.0E-25 T 29-03-2018 MC49_RS11270 03094941a084acd18f60bdbae39c2f3a 639 Gene3D G3DSA:3.40.50.300 11 83 1.7E-6 T 29-03-2018 MC49_RS11270 03094941a084acd18f60bdbae39c2f3a 639 Pfam PF16326 ABC transporter C-terminal domain 565 633 1.4E-17 T 29-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 MC49_RS11270 03094941a084acd18f60bdbae39c2f3a 639 ProSitePatterns PS00211 ABC transporters family signature. 441 455 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS11270 03094941a084acd18f60bdbae39c2f3a 639 SMART SM00382 28 230 9.5E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS11270 03094941a084acd18f60bdbae39c2f3a 639 SMART SM00382 344 515 3.0E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS11270 03094941a084acd18f60bdbae39c2f3a 639 Pfam PF00005 ABC transporter 337 469 6.9E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS11270 03094941a084acd18f60bdbae39c2f3a 639 Pfam PF00005 ABC transporter 19 185 1.0E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS11270 03094941a084acd18f60bdbae39c2f3a 639 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS11270 03094941a084acd18f60bdbae39c2f3a 639 Gene3D G3DSA:3.40.50.300 292 561 2.1E-57 T 29-03-2018 MC49_RS11270 03094941a084acd18f60bdbae39c2f3a 639 Pfam PF12848 ABC transporter 224 299 2.9E-9 T 29-03-2018 IPR032781 ABC-transporter extension domain MC49_RS11270 03094941a084acd18f60bdbae39c2f3a 639 SUPERFAMILY SSF52540 310 502 7.22E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS11270 03094941a084acd18f60bdbae39c2f3a 639 Gene3D G3DSA:3.40.50.300 89 291 2.6E-43 T 29-03-2018 MC49_RS11270 03094941a084acd18f60bdbae39c2f3a 639 SUPERFAMILY SSF52540 126 239 5.02E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS11270 03094941a084acd18f60bdbae39c2f3a 639 SUPERFAMILY SSF52540 4 94 5.02E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS13315 033f1c63a536571f4910b1d58a9350d0 1011 Pfam PF08339 RTX C-terminal domain 859 980 7.9E-12 T 29-03-2018 IPR013550 RTX, C-terminal MC49_RS13315 033f1c63a536571f4910b1d58a9350d0 1011 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 756 772 0.034 T 29-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 MC49_RS13315 033f1c63a536571f4910b1d58a9350d0 1011 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 738 754 0.0023 T 29-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 MC49_RS13315 033f1c63a536571f4910b1d58a9350d0 1011 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 803 819 0.0067 T 29-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 MC49_RS13315 033f1c63a536571f4910b1d58a9350d0 1011 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 821 836 0.054 T 29-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 MC49_RS13315 033f1c63a536571f4910b1d58a9350d0 1011 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 773 789 0.1 T 29-03-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 MC49_RS13315 033f1c63a536571f4910b1d58a9350d0 1011 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 808 826 - T 29-03-2018 IPR018511 Hemolysin-type calcium-binding conserved site MC49_RS13315 033f1c63a536571f4910b1d58a9350d0 1011 PRINTS PR01488 Gram-negative bacterial RTX toxin determinant A family signature 268 289 1.7E-87 T 29-03-2018 IPR003995 RTX toxin determinant A GO:0005509|GO:0005576|GO:0009405 MC49_RS13315 033f1c63a536571f4910b1d58a9350d0 1011 PRINTS PR01488 Gram-negative bacterial RTX toxin determinant A family signature 729 750 1.7E-87 T 29-03-2018 IPR003995 RTX toxin determinant A GO:0005509|GO:0005576|GO:0009405 MC49_RS13315 033f1c63a536571f4910b1d58a9350d0 1011 PRINTS PR01488 Gram-negative bacterial RTX toxin determinant A family signature 390 410 1.7E-87 T 29-03-2018 IPR003995 RTX toxin determinant A GO:0005509|GO:0005576|GO:0009405 MC49_RS13315 033f1c63a536571f4910b1d58a9350d0 1011 PRINTS PR01488 Gram-negative bacterial RTX toxin determinant A family signature 425 441 1.7E-87 T 29-03-2018 IPR003995 RTX toxin determinant A GO:0005509|GO:0005576|GO:0009405 MC49_RS13315 033f1c63a536571f4910b1d58a9350d0 1011 PRINTS PR01488 Gram-negative bacterial RTX toxin determinant A family signature 334 352 1.7E-87 T 29-03-2018 IPR003995 RTX toxin determinant A GO:0005509|GO:0005576|GO:0009405 MC49_RS13315 033f1c63a536571f4910b1d58a9350d0 1011 PRINTS PR01488 Gram-negative bacterial RTX toxin determinant A family signature 532 556 1.7E-87 T 29-03-2018 IPR003995 RTX toxin determinant A GO:0005509|GO:0005576|GO:0009405 MC49_RS13315 033f1c63a536571f4910b1d58a9350d0 1011 PRINTS PR01488 Gram-negative bacterial RTX toxin determinant A family signature 478 499 1.7E-87 T 29-03-2018 IPR003995 RTX toxin determinant A GO:0005509|GO:0005576|GO:0009405 MC49_RS13315 033f1c63a536571f4910b1d58a9350d0 1011 PRINTS PR00313 NodO calcium binding signature 830 839 3.8E-11 T 29-03-2018 MC49_RS13315 033f1c63a536571f4910b1d58a9350d0 1011 PRINTS PR00313 NodO calcium binding signature 783 791 3.8E-11 T 29-03-2018 MC49_RS13315 033f1c63a536571f4910b1d58a9350d0 1011 PRINTS PR00313 NodO calcium binding signature 803 811 3.8E-11 T 29-03-2018 MC49_RS13315 033f1c63a536571f4910b1d58a9350d0 1011 PRINTS PR00313 NodO calcium binding signature 735 746 3.8E-11 T 29-03-2018 MC49_RS13315 033f1c63a536571f4910b1d58a9350d0 1011 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 817 835 - T 29-03-2018 IPR018511 Hemolysin-type calcium-binding conserved site MC49_RS13315 033f1c63a536571f4910b1d58a9350d0 1011 Pfam PF02382 RTX N-terminal domain 17 643 1.1E-296 T 29-03-2018 IPR018504 RTX N-terminal GO:0005509|GO:0005576|GO:0009405 MC49_RS13315 033f1c63a536571f4910b1d58a9350d0 1011 Gene3D G3DSA:2.150.10.10 786 924 5.1E-21 T 29-03-2018 MC49_RS13315 033f1c63a536571f4910b1d58a9350d0 1011 Gene3D G3DSA:2.150.10.10 633 785 5.4E-17 T 29-03-2018 MC49_RS13315 033f1c63a536571f4910b1d58a9350d0 1011 SUPERFAMILY SSF51120 715 893 4.11E-29 T 29-03-2018 IPR011049 Serralysin-like metalloprotease, C-terminal MC49_RS04990 210a59435e8f7349e0f92fa49e766c31 401 Gene3D G3DSA:1.20.1250.20 204 401 9.1E-16 T 29-03-2018 MC49_RS04990 210a59435e8f7349e0f92fa49e766c31 401 Gene3D G3DSA:1.20.1250.20 5 193 5.1E-32 T 29-03-2018 MC49_RS04990 210a59435e8f7349e0f92fa49e766c31 401 SUPERFAMILY SSF103473 7 392 1.44E-56 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS04990 210a59435e8f7349e0f92fa49e766c31 401 ProSitePatterns PS00216 Sugar transport proteins signature 1. 61 77 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MC49_RS04990 210a59435e8f7349e0f92fa49e766c31 401 Pfam PF07690 Major Facilitator Superfamily 9 350 4.9E-44 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS04990 210a59435e8f7349e0f92fa49e766c31 401 PRINTS PR01035 Tetracycline resistance protein signature 101 122 4.1E-144 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MC49_RS04990 210a59435e8f7349e0f92fa49e766c31 401 PRINTS PR01035 Tetracycline resistance protein signature 74 98 4.1E-144 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MC49_RS04990 210a59435e8f7349e0f92fa49e766c31 401 PRINTS PR01035 Tetracycline resistance protein signature 246 266 4.1E-144 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MC49_RS04990 210a59435e8f7349e0f92fa49e766c31 401 PRINTS PR01035 Tetracycline resistance protein signature 334 357 4.1E-144 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MC49_RS04990 210a59435e8f7349e0f92fa49e766c31 401 PRINTS PR01035 Tetracycline resistance protein signature 274 295 4.1E-144 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MC49_RS04990 210a59435e8f7349e0f92fa49e766c31 401 PRINTS PR01035 Tetracycline resistance protein signature 43 62 4.1E-144 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MC49_RS04990 210a59435e8f7349e0f92fa49e766c31 401 PRINTS PR01035 Tetracycline resistance protein signature 159 179 4.1E-144 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MC49_RS04990 210a59435e8f7349e0f92fa49e766c31 401 PRINTS PR01035 Tetracycline resistance protein signature 364 383 4.1E-144 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MC49_RS04990 210a59435e8f7349e0f92fa49e766c31 401 PRINTS PR01035 Tetracycline resistance protein signature 14 30 4.1E-144 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MC49_RS04990 210a59435e8f7349e0f92fa49e766c31 401 PRINTS PR01035 Tetracycline resistance protein signature 299 319 4.1E-144 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MC49_RS04990 210a59435e8f7349e0f92fa49e766c31 401 PRINTS PR01035 Tetracycline resistance protein signature 131 153 4.1E-144 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MC49_RS04990 210a59435e8f7349e0f92fa49e766c31 401 PRINTS PR01035 Tetracycline resistance protein signature 217 234 4.1E-144 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MC49_RS06485 2e47675e083fa4641059e41652d62508 525 Gene3D G3DSA:1.20.120.30 25 182 2.4E-7 T 29-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain MC49_RS06485 2e47675e083fa4641059e41652d62508 525 Gene3D G3DSA:1.10.287.950 183 320 7.6E-11 T 29-03-2018 MC49_RS06485 2e47675e083fa4641059e41652d62508 525 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 332 487 4.1E-51 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MC49_RS06485 2e47675e083fa4641059e41652d62508 525 Gene3D G3DSA:1.10.287.950 321 523 1.9E-44 T 29-03-2018 MC49_RS06485 2e47675e083fa4641059e41652d62508 525 SUPERFAMILY SSF58104 256 520 1.27E-64 T 29-03-2018 MC49_RS06485 2e47675e083fa4641059e41652d62508 525 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 370 397 2.1E-48 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS06485 2e47675e083fa4641059e41652d62508 525 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 399 428 2.1E-48 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS06485 2e47675e083fa4641059e41652d62508 525 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 293 322 2.1E-48 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS06485 2e47675e083fa4641059e41652d62508 525 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 447 476 2.1E-48 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS06485 2e47675e083fa4641059e41652d62508 525 Pfam PF12729 Four helix bundle sensory module for signal transduction 5 180 1.2E-12 T 29-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain MC49_RS06485 2e47675e083fa4641059e41652d62508 525 SMART SM00283 272 519 2.2E-85 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MC49_RS16560 f39f9d49e208db3bd66e491a50562e30 222 Gene3D G3DSA:1.10.150.240 31 76 1.1E-12 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 MC49_RS16560 f39f9d49e208db3bd66e491a50562e30 222 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 93 183 7.4E-11 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MC49_RS16560 f39f9d49e208db3bd66e491a50562e30 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 5 16 1.2E-5 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MC49_RS16560 f39f9d49e208db3bd66e491a50562e30 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 97 110 1.2E-5 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MC49_RS16560 f39f9d49e208db3bd66e491a50562e30 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 127 143 1.2E-5 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MC49_RS16560 f39f9d49e208db3bd66e491a50562e30 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 145 165 1.2E-5 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MC49_RS16560 f39f9d49e208db3bd66e491a50562e30 222 Gene3D G3DSA:3.40.50.1000 2 30 0.088 T 29-03-2018 IPR023214 HAD-like domain MC49_RS16560 f39f9d49e208db3bd66e491a50562e30 222 SUPERFAMILY SSF56784 6 205 1.09E-39 T 29-03-2018 IPR023214 HAD-like domain MC49_RS16560 f39f9d49e208db3bd66e491a50562e30 222 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 183 1.3E-22 T 29-03-2018 IPR023214 HAD-like domain MC49_RS16560 f39f9d49e208db3bd66e491a50562e30 222 Gene3D G3DSA:3.40.50.1000 77 208 3.5E-19 T 29-03-2018 IPR023214 HAD-like domain MC49_RS05895 52d1cd7ccbcae71925810cf1c5da6acd 386 Gene3D G3DSA:3.40.640.10 1 247 8.4E-54 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS05895 52d1cd7ccbcae71925810cf1c5da6acd 386 PIRSF PIRSF001434 1 384 1.2E-130 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MC49_RS05895 52d1cd7ccbcae71925810cf1c5da6acd 386 Gene3D G3DSA:3.90.1150.10 248 386 2.2E-47 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS05895 52d1cd7ccbcae71925810cf1c5da6acd 386 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 7 381 1.2E-135 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MC49_RS05895 52d1cd7ccbcae71925810cf1c5da6acd 386 SUPERFAMILY SSF53383 8 383 5.84E-114 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS05895 52d1cd7ccbcae71925810cf1c5da6acd 386 TIGRFAM TIGR02080 O_succ_thio_ly: O-succinylhomoserine (thiol)-lyase 3 383 3.1E-187 T 29-03-2018 IPR011821 O-succinylhomoserine (thiol)-lyase KEGG: 00270+2.5.1.48|KEGG: 00450+2.5.1.48|KEGG: 00920+2.5.1.48|MetaCyc: PWY-801 MC49_RS05895 52d1cd7ccbcae71925810cf1c5da6acd 386 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 190 204 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 SUPERFAMILY SSF49373 755 853 2.55E-17 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 SUPERFAMILY SSF49373 1671 1763 4.51E-19 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 SUPERFAMILY SSF49373 1980 2072 6.8E-16 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 SUPERFAMILY SSF49373 955 1053 8.83E-16 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 SUPERFAMILY SSF49373 1365 1461 1.35E-19 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 Pfam PF09134 Invasin, domain 3 1367 1462 1.1E-23 T 29-03-2018 IPR015217 Invasin, domain 3 MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 Pfam PF09134 Invasin, domain 3 1978 2076 7.8E-21 T 29-03-2018 IPR015217 Invasin, domain 3 MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 Pfam PF09134 Invasin, domain 3 1265 1362 1.5E-23 T 29-03-2018 IPR015217 Invasin, domain 3 MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 Pfam PF09134 Invasin, domain 3 1468 1564 9.7E-23 T 29-03-2018 IPR015217 Invasin, domain 3 MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 Pfam PF09134 Invasin, domain 3 1570 1666 2.1E-21 T 29-03-2018 IPR015217 Invasin, domain 3 MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 Pfam PF09134 Invasin, domain 3 1877 1972 1.5E-23 T 29-03-2018 IPR015217 Invasin, domain 3 MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 Pfam PF09134 Invasin, domain 3 1672 1768 2.5E-22 T 29-03-2018 IPR015217 Invasin, domain 3 MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 Pfam PF09134 Invasin, domain 3 1163 1260 4.5E-22 T 29-03-2018 IPR015217 Invasin, domain 3 MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 Pfam PF09134 Invasin, domain 3 1060 1158 4.0E-22 T 29-03-2018 IPR015217 Invasin, domain 3 MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 Pfam PF09134 Invasin, domain 3 1774 1872 1.1E-22 T 29-03-2018 IPR015217 Invasin, domain 3 MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 SUPERFAMILY SSF49373 1569 1661 4.32E-19 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 SUPERFAMILY SSF49373 1776 1869 5.1E-17 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 SUPERFAMILY SSF49373 1062 1155 2.38E-18 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 Pfam PF11924 Inverse autotransporter, beta-domain 166 438 6.9E-98 T 29-03-2018 IPR024519 Inverse autotransporter, beta-domain MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 SUPERFAMILY SSF49373 1468 1559 1.63E-18 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 Gene3D G3DSA:2.60.120.260 1821 1924 2.1E-19 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 Gene3D G3DSA:2.60.120.260 1925 2025 1.8E-20 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 Gene3D G3DSA:2.60.120.260 1517 1618 5.4E-22 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 Gene3D G3DSA:2.60.120.260 437 598 9.6E-10 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 Gene3D G3DSA:2.60.120.260 1619 1719 1.4E-19 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 Gene3D G3DSA:2.60.120.260 914 1010 8.9E-17 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 Gene3D G3DSA:2.60.120.260 599 708 3.0E-12 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 Gene3D G3DSA:2.60.120.260 1210 1308 2.2E-19 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 Gene3D G3DSA:2.60.120.260 1104 1209 2.2E-23 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 Gene3D G3DSA:2.60.120.260 810 913 3.4E-14 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 Gene3D G3DSA:2.60.120.260 709 809 5.5E-13 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 Gene3D G3DSA:2.60.120.260 1720 1820 1.1E-21 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 Gene3D G3DSA:2.60.120.260 1011 1103 1.3E-16 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 Gene3D G3DSA:2.60.120.260 2026 2117 4.2E-11 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 Gene3D G3DSA:2.60.120.260 1309 1412 1.2E-23 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 Gene3D G3DSA:2.60.120.260 1413 1516 3.5E-22 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 Pfam PF02369 Bacterial Ig-like domain (group 1) 868 952 2.5E-11 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 Pfam PF02369 Bacterial Ig-like domain (group 1) 759 850 2.3E-10 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 Gene3D G3DSA:2.60.40.1120 2118 2169 0.036 T 29-03-2018 MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 SUPERFAMILY SSF49373 1164 1257 2.88E-17 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 SUPERFAMILY SSF49373 560 660 1.18E-7 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 SMART SM00634 552 655 0.11 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 SMART SM00634 1573 1661 2.2E-13 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 SMART SM00634 1675 1763 4.7E-12 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 SMART SM00634 1267 1355 1.6E-16 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 SMART SM00634 1879 1967 6.3E-16 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 SMART SM00634 665 754 4.1E-6 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 SMART SM00634 1471 1559 3.9E-12 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 SMART SM00634 1369 1457 3.4E-14 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 SMART SM00634 1981 2069 3.5E-7 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 SMART SM00634 1777 1865 7.7E-10 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 SMART SM00634 1063 1151 1.4E-8 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 SMART SM00634 963 1052 5.4E-7 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 SMART SM00634 2083 2175 0.14 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 SMART SM00634 867 954 6.1E-10 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 SMART SM00634 1165 1253 1.6E-15 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 SMART SM00634 763 852 4.5E-7 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 SUPERFAMILY SSF49373 1264 1358 1.12E-18 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 SUPERFAMILY SSF49373 657 755 1.31E-14 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 SUPERFAMILY SSF49373 2074 2152 3.4E-6 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 SUPERFAMILY SSF49373 1875 1966 2.94E-19 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02890 04b2fe680d845dc14d71544aa4de4380 2193 SUPERFAMILY SSF49373 868 958 1.22E-18 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS07810 c0372a06ff37ba881d758cebf78093c4 273 Pfam PF00226 DnaJ domain 208 269 1.2E-10 T 29-03-2018 IPR001623 DnaJ domain MC49_RS07810 c0372a06ff37ba881d758cebf78093c4 273 Pfam PF05099 Tellurite resistance protein TerB 37 171 1.4E-12 T 29-03-2018 IPR007791 Co-chaperone DjlA, N-terminal MC49_RS07810 c0372a06ff37ba881d758cebf78093c4 273 Gene3D G3DSA:1.10.3680.10 39 172 8.5E-26 T 29-03-2018 IPR029024 TerB-like MC49_RS07810 c0372a06ff37ba881d758cebf78093c4 273 SMART SM00271 206 271 6.9E-15 T 29-03-2018 IPR001623 DnaJ domain MC49_RS07810 c0372a06ff37ba881d758cebf78093c4 273 Hamap MF_01153 Co-chaperone protein DjlA [djlA]. 3 272 39.393 T 29-03-2018 IPR023749 Co-chaperone DjlA GO:0051087 MC49_RS07810 c0372a06ff37ba881d758cebf78093c4 273 PRINTS PR00625 DnaJ domain signature 209 227 5.4E-8 T 29-03-2018 IPR001623 DnaJ domain MC49_RS07810 c0372a06ff37ba881d758cebf78093c4 273 PRINTS PR00625 DnaJ domain signature 251 271 5.4E-8 T 29-03-2018 IPR001623 DnaJ domain MC49_RS07810 c0372a06ff37ba881d758cebf78093c4 273 PRINTS PR00625 DnaJ domain signature 227 242 5.4E-8 T 29-03-2018 IPR001623 DnaJ domain MC49_RS07810 c0372a06ff37ba881d758cebf78093c4 273 SUPERFAMILY SSF46565 132 269 1.88E-29 T 29-03-2018 IPR001623 DnaJ domain MC49_RS07810 c0372a06ff37ba881d758cebf78093c4 273 Gene3D G3DSA:1.10.287.110 173 271 2.8E-15 T 29-03-2018 IPR001623 DnaJ domain MC49_RS03355 9cb2c575915dc7ccb00391cec626261c 718 SMART SM00316 627 697 1.6E-27 T 29-03-2018 IPR022967 RNA-binding domain, S1 MC49_RS03355 9cb2c575915dc7ccb00391cec626261c 718 Pfam PF03725 3' exoribonuclease family, domain 2 147 210 2.0E-15 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MC49_RS03355 9cb2c575915dc7ccb00391cec626261c 718 Pfam PF03725 3' exoribonuclease family, domain 2 467 534 2.2E-4 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MC49_RS03355 9cb2c575915dc7ccb00391cec626261c 718 PIRSF PIRSF005499 2 718 1.7E-297 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MC49_RS03355 9cb2c575915dc7ccb00391cec626261c 718 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 3 700 30.291 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MC49_RS03355 9cb2c575915dc7ccb00391cec626261c 718 Gene3D G3DSA:3.30.230.70 323 551 7.2E-57 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MC49_RS03355 9cb2c575915dc7ccb00391cec626261c 718 SMART SM00322 559 624 5.3E-12 T 29-03-2018 IPR004087 K Homology domain GO:0003676 MC49_RS03355 9cb2c575915dc7ccb00391cec626261c 718 SUPERFAMILY SSF55666 457 556 1.04E-26 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MC49_RS03355 9cb2c575915dc7ccb00391cec626261c 718 Gene3D G3DSA:1.10.10.400 247 322 1.1E-17 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MC49_RS03355 9cb2c575915dc7ccb00391cec626261c 718 Pfam PF01138 3' exoribonuclease family, domain 1 16 144 6.5E-19 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MC49_RS03355 9cb2c575915dc7ccb00391cec626261c 718 Pfam PF01138 3' exoribonuclease family, domain 1 331 463 7.2E-22 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MC49_RS03355 9cb2c575915dc7ccb00391cec626261c 718 Gene3D G3DSA:2.40.50.140 624 705 2.9E-26 T 29-03-2018 MC49_RS03355 9cb2c575915dc7ccb00391cec626261c 718 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 242 327 1.2E-19 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MC49_RS03355 9cb2c575915dc7ccb00391cec626261c 718 SUPERFAMILY SSF46915 238 327 4.18E-15 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MC49_RS03355 9cb2c575915dc7ccb00391cec626261c 718 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 10 698 0.0 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 MC49_RS03355 9cb2c575915dc7ccb00391cec626261c 718 Pfam PF00575 S1 RNA binding domain 626 697 3.3E-21 T 29-03-2018 IPR003029 S1 domain GO:0003676 MC49_RS03355 9cb2c575915dc7ccb00391cec626261c 718 Pfam PF00013 KH domain 564 621 1.1E-8 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 MC49_RS03355 9cb2c575915dc7ccb00391cec626261c 718 SUPERFAMILY SSF54791 561 629 2.88E-17 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 MC49_RS03355 9cb2c575915dc7ccb00391cec626261c 718 SUPERFAMILY SSF55666 145 235 1.82E-30 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MC49_RS03355 9cb2c575915dc7ccb00391cec626261c 718 Gene3D G3DSA:3.30.1370.10 561 623 5.9E-14 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 MC49_RS03355 9cb2c575915dc7ccb00391cec626261c 718 SUPERFAMILY SSF54211 4 144 9.62E-50 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MC49_RS03355 9cb2c575915dc7ccb00391cec626261c 718 SUPERFAMILY SSF54211 304 475 2.02E-45 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MC49_RS03355 9cb2c575915dc7ccb00391cec626261c 718 Gene3D G3DSA:3.30.230.70 13 246 9.2E-53 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MC49_RS03355 9cb2c575915dc7ccb00391cec626261c 718 SUPERFAMILY SSF50249 615 699 1.1E-22 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS16215 d26b5ac020afc624d254137af630e431 243 Pfam PF00308 Bacterial dnaA protein 26 222 4.0E-20 T 29-03-2018 IPR013317 Chromosomal replication initiator protein DnaA MC49_RS16215 d26b5ac020afc624d254137af630e431 243 TIGRFAM TIGR03420 DnaA_homol_Hda: DnaA regulatory inactivator Hda 16 241 7.1E-84 T 29-03-2018 IPR017788 DnaA regulatory inactivator Hda GO:0032297 MC49_RS16215 d26b5ac020afc624d254137af630e431 243 Gene3D G3DSA:1.10.8.60 177 243 5.8E-15 T 29-03-2018 MC49_RS16215 d26b5ac020afc624d254137af630e431 243 Hamap MF_01158 DnaA regulatory inactivator Hda [hda]. 15 243 55.547 T 29-03-2018 IPR022864 DnaA regulatory inactivator Hda, Enterobacteriaceae MC49_RS16215 d26b5ac020afc624d254137af630e431 243 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 53 73 2.1E-6 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MC49_RS16215 d26b5ac020afc624d254137af630e431 243 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 141 168 2.1E-6 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MC49_RS16215 d26b5ac020afc624d254137af630e431 243 Gene3D G3DSA:3.40.50.300 15 174 1.3E-10 T 29-03-2018 MC49_RS16215 d26b5ac020afc624d254137af630e431 243 SUPERFAMILY SSF52540 24 222 4.58E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS02670 015eaaf74e3ba1d3f32df32b51ef7259 198 SUPERFAMILY SSF140478 27 183 8.5E-47 T 29-03-2018 IPR023353 LemA-like domain MC49_RS02670 015eaaf74e3ba1d3f32df32b51ef7259 198 Pfam PF04011 LemA family 10 196 1.3E-58 T 29-03-2018 IPR007156 LemA MC49_RS02670 015eaaf74e3ba1d3f32df32b51ef7259 198 Gene3D G3DSA:1.20.1440.20 14 196 6.2E-48 T 29-03-2018 MC49_RS10280 170dfa9fd651ea26734310d09262746c 676 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 529 649 5.9E-46 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 MC49_RS10280 170dfa9fd651ea26734310d09262746c 676 Gene3D G3DSA:2.70.70.10 515 676 2.7E-53 T 29-03-2018 MC49_RS10280 170dfa9fd651ea26734310d09262746c 676 TIGRFAM TIGR01998 PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component 3 495 6.5E-203 T 29-03-2018 IPR010974 Phosphotransferase system, N-acetylglucosamine-specific IIBC component GO:0008982|GO:0009401|GO:0015572|GO:0016021|GO:0019866 MC49_RS10280 170dfa9fd651ea26734310d09262746c 676 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 383 484 1.1E-21 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 MC49_RS10280 170dfa9fd651ea26734310d09262746c 676 Pfam PF02378 Phosphotransferase system, EIIC 12 324 2.7E-74 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 MC49_RS10280 170dfa9fd651ea26734310d09262746c 676 Gene3D G3DSA:3.30.1360.60 422 498 4.3E-23 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 MC49_RS10280 170dfa9fd651ea26734310d09262746c 676 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 437 454 - T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 MC49_RS10280 170dfa9fd651ea26734310d09262746c 676 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 528 652 6.0E-46 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 MC49_RS10280 170dfa9fd651ea26734310d09262746c 676 Pfam PF00367 phosphotransferase system, EIIB 426 459 5.8E-13 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 MC49_RS10280 170dfa9fd651ea26734310d09262746c 676 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 591 603 - T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 MC49_RS10280 170dfa9fd651ea26734310d09262746c 676 SUPERFAMILY SSF55604 425 498 1.83E-18 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 MC49_RS10280 170dfa9fd651ea26734310d09262746c 676 SUPERFAMILY SSF51261 527 674 2.44E-50 T 29-03-2018 IPR011055 Duplicated hybrid motif MC49_RS18025 959c9be4008632bdfe3aa37f5c504afc 574 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 499 511 4.5E-31 T 29-03-2018 MC49_RS18025 959c9be4008632bdfe3aa37f5c504afc 574 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 463 478 4.5E-31 T 29-03-2018 MC49_RS18025 959c9be4008632bdfe3aa37f5c504afc 574 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 446 461 4.5E-31 T 29-03-2018 MC49_RS18025 959c9be4008632bdfe3aa37f5c504afc 574 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 292 311 4.5E-31 T 29-03-2018 MC49_RS18025 959c9be4008632bdfe3aa37f5c504afc 574 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 2 565 3.4E-253 T 29-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 MC49_RS18025 959c9be4008632bdfe3aa37f5c504afc 574 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 249 540 4.0E-126 T 29-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 MC49_RS18025 959c9be4008632bdfe3aa37f5c504afc 574 SUPERFAMILY SSF52009 124 244 6.28E-37 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MC49_RS18025 959c9be4008632bdfe3aa37f5c504afc 574 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 183 194 - T 29-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 MC49_RS18025 959c9be4008632bdfe3aa37f5c504afc 574 Gene3D G3DSA:3.50.30.10 145 243 4.1E-26 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MC49_RS18025 959c9be4008632bdfe3aa37f5c504afc 574 SUPERFAMILY SSF47831 26 142 6.54E-35 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 MC49_RS18025 959c9be4008632bdfe3aa37f5c504afc 574 Pfam PF00391 PEP-utilising enzyme, mobile domain 152 221 2.5E-23 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MC49_RS18025 959c9be4008632bdfe3aa37f5c504afc 574 SUPERFAMILY SSF51621 248 548 7.33E-112 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MC49_RS18025 959c9be4008632bdfe3aa37f5c504afc 574 Gene3D G3DSA:1.10.274.10 24 143 6.8E-38 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 MC49_RS18025 959c9be4008632bdfe3aa37f5c504afc 574 PIRSF PIRSF000732 1 573 1.9E-224 T 29-03-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 MC49_RS18025 959c9be4008632bdfe3aa37f5c504afc 574 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 446 464 - T 29-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 MC49_RS18025 959c9be4008632bdfe3aa37f5c504afc 574 Pfam PF05524 PEP-utilising enzyme, N-terminal 4 125 4.6E-32 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 MC49_RS18025 959c9be4008632bdfe3aa37f5c504afc 574 Gene3D G3DSA:3.20.20.60 249 572 9.6E-108 T 29-03-2018 MC49_RS02020 f1c952a1459b010c3a314bcfedd3386d 144 ProDom PD021295 MATURATION HYDROGENLYASE FORMATE HYCH LYASE HYCE PROCESSING OXIDOREDUCTASE J COMPONENT 11 142 2.0E-42 T 29-03-2018 IPR010005 Formate hydrogenlyase maturation HycH MC49_RS02020 f1c952a1459b010c3a314bcfedd3386d 144 Pfam PF07450 Formate hydrogenlyase maturation protein HycH 14 142 1.5E-56 T 29-03-2018 IPR010005 Formate hydrogenlyase maturation HycH MC49_RS07595 86ca1f816ee1135c10fd6bf931eaaaae 86 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 13 86 5.0E-32 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS07595 86ca1f816ee1135c10fd6bf931eaaaae 86 Pfam PF01649 Ribosomal protein S20 2 84 3.3E-28 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS07595 86ca1f816ee1135c10fd6bf931eaaaae 86 Gene3D G3DSA:1.20.58.110 1 86 7.2E-30 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS07595 86ca1f816ee1135c10fd6bf931eaaaae 86 SUPERFAMILY SSF46992 3 86 5.89E-32 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS07595 86ca1f816ee1135c10fd6bf931eaaaae 86 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.652 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS07595 86ca1f816ee1135c10fd6bf931eaaaae 86 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 85 2.0E-32 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS14060 6e7ac5fa8d2ba156796e1a49611ecafd 204 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 204 7.2E-68 T 29-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 MC49_RS14060 6e7ac5fa8d2ba156796e1a49611ecafd 204 Pfam PF14520 Helix-hairpin-helix domain 72 130 1.0E-17 T 29-03-2018 MC49_RS14060 6e7ac5fa8d2ba156796e1a49611ecafd 204 SMART SM00278 108 127 0.018 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MC49_RS14060 6e7ac5fa8d2ba156796e1a49611ecafd 204 SMART SM00278 73 92 0.054 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MC49_RS14060 6e7ac5fa8d2ba156796e1a49611ecafd 204 Gene3D G3DSA:1.10.8.10 158 203 1.8E-14 T 29-03-2018 MC49_RS14060 6e7ac5fa8d2ba156796e1a49611ecafd 204 SUPERFAMILY SSF50249 2 63 8.0E-18 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS14060 6e7ac5fa8d2ba156796e1a49611ecafd 204 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 204 32.828 T 29-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 MC49_RS14060 6e7ac5fa8d2ba156796e1a49611ecafd 204 SUPERFAMILY SSF46929 159 202 1.09E-9 T 29-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 MC49_RS14060 6e7ac5fa8d2ba156796e1a49611ecafd 204 SUPERFAMILY SSF47781 66 136 3.46E-22 T 29-03-2018 IPR010994 RuvA domain 2-like MC49_RS14060 6e7ac5fa8d2ba156796e1a49611ecafd 204 Gene3D G3DSA:1.10.150.20 79 112 1.8E-12 T 29-03-2018 MC49_RS14060 6e7ac5fa8d2ba156796e1a49611ecafd 204 Gene3D G3DSA:1.10.340.30 52 78 0.11 T 29-03-2018 MC49_RS14060 6e7ac5fa8d2ba156796e1a49611ecafd 204 Gene3D G3DSA:2.40.50.140 1 51 2.0E-22 T 29-03-2018 MC49_RS14060 6e7ac5fa8d2ba156796e1a49611ecafd 204 Gene3D G3DSA:1.10.150.20 113 136 0.0052 T 29-03-2018 MC49_RS14060 6e7ac5fa8d2ba156796e1a49611ecafd 204 Pfam PF01330 RuvA N terminal domain 2 62 9.8E-19 T 29-03-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 MC49_RS14060 6e7ac5fa8d2ba156796e1a49611ecafd 204 Pfam PF07499 RuvA, C-terminal domain 160 202 3.7E-14 T 29-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 MC49_RS14405 bce96fabf2c3c14fc369496deb9c2b3c 251 SUPERFAMILY SSF46785 97 188 4.3E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS14405 bce96fabf2c3c14fc369496deb9c2b3c 251 Pfam PF03551 Transcriptional regulator PadR-like family 102 172 3.1E-18 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal MC49_RS14405 bce96fabf2c3c14fc369496deb9c2b3c 251 Gene3D G3DSA:1.10.10.10 82 200 6.9E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS01005 45c9dbbdac9252e57568fbf3edfa6970 71 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 4.9E-17 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS01005 45c9dbbdac9252e57568fbf3edfa6970 71 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 4.9E-17 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS01005 45c9dbbdac9252e57568fbf3edfa6970 71 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 4.9E-17 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS01005 45c9dbbdac9252e57568fbf3edfa6970 71 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 4.9E-17 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS01005 45c9dbbdac9252e57568fbf3edfa6970 71 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 29-03-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS01005 45c9dbbdac9252e57568fbf3edfa6970 71 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 15 56 7.0E-15 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS01005 45c9dbbdac9252e57568fbf3edfa6970 71 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 21.664 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS01005 45c9dbbdac9252e57568fbf3edfa6970 71 Gene3D G3DSA:1.20.5.1150 16 52 1.1E-17 T 29-03-2018 MC49_RS01005 45c9dbbdac9252e57568fbf3edfa6970 71 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 2 59 2.8E-24 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS01005 45c9dbbdac9252e57568fbf3edfa6970 71 Pfam PF01165 Ribosomal protein S21 4 56 9.2E-22 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS06605 07055b02cb3ba045eebade5a29da6edf 1226 TIGRFAM TIGR02082 metH: methionine synthase 12 1190 0.0 T 29-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MC49_RS06605 07055b02cb3ba045eebade5a29da6edf 1226 SMART SM01018 656 739 2.7E-42 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MC49_RS06605 07055b02cb3ba045eebade5a29da6edf 1226 Pfam PF02607 B12 binding domain 658 732 7.4E-23 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MC49_RS06605 07055b02cb3ba045eebade5a29da6edf 1226 Gene3D G3DSA:1.10.288.10 937 993 2.6E-23 T 29-03-2018 MC49_RS06605 07055b02cb3ba045eebade5a29da6edf 1226 SUPERFAMILY SSF51717 356 630 7.98E-89 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MC49_RS06605 07055b02cb3ba045eebade5a29da6edf 1226 PIRSF PIRSF000381 1 1193 0.0 T 29-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MC49_RS06605 07055b02cb3ba045eebade5a29da6edf 1226 Pfam PF00809 Pterin binding enzyme 360 598 1.6E-60 T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MC49_RS06605 07055b02cb3ba045eebade5a29da6edf 1226 Gene3D G3DSA:1.10.1240.10 651 736 2.6E-35 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MC49_RS06605 07055b02cb3ba045eebade5a29da6edf 1226 SUPERFAMILY SSF47644 652 737 1.19E-27 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MC49_RS06605 07055b02cb3ba045eebade5a29da6edf 1226 Gene3D G3DSA:3.20.20.20 345 644 3.8E-73 T 29-03-2018 MC49_RS06605 07055b02cb3ba045eebade5a29da6edf 1226 Gene3D G3DSA:3.20.20.330 1 341 9.2E-110 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 MC49_RS06605 07055b02cb3ba045eebade5a29da6edf 1226 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 937 1206 6.3E-120 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MC49_RS06605 07055b02cb3ba045eebade5a29da6edf 1226 Pfam PF02574 Homocysteine S-methyltransferase 17 325 1.1E-78 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 MC49_RS06605 07055b02cb3ba045eebade5a29da6edf 1226 Gene3D G3DSA:1.10.288.10 1012 1080 8.2E-17 T 29-03-2018 MC49_RS06605 07055b02cb3ba045eebade5a29da6edf 1226 SUPERFAMILY SSF52242 742 892 1.27E-47 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 MC49_RS06605 07055b02cb3ba045eebade5a29da6edf 1226 Pfam PF02310 B12 binding domain 747 840 3.9E-18 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 MC49_RS06605 07055b02cb3ba045eebade5a29da6edf 1226 SUPERFAMILY SSF56507 902 1225 2.09E-128 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MC49_RS06605 07055b02cb3ba045eebade5a29da6edf 1226 SUPERFAMILY SSF82282 7 399 1.96E-116 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 MC49_RS06605 07055b02cb3ba045eebade5a29da6edf 1226 Gene3D G3DSA:3.10.196.10 1081 1226 9.2E-65 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MC49_RS06605 07055b02cb3ba045eebade5a29da6edf 1226 Gene3D G3DSA:3.40.50.280 742 894 3.5E-58 T 29-03-2018 MC49_RS01760 a63ede92fcb483882b418fccc3fca112 895 PRINTS PR00344 Bacterial sensor protein C-terminal signature 829 839 5.0E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS01760 a63ede92fcb483882b418fccc3fca112 895 PRINTS PR00344 Bacterial sensor protein C-terminal signature 811 825 5.0E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS01760 a63ede92fcb483882b418fccc3fca112 895 PRINTS PR00344 Bacterial sensor protein C-terminal signature 868 881 5.0E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS01760 a63ede92fcb483882b418fccc3fca112 895 PRINTS PR00344 Bacterial sensor protein C-terminal signature 844 862 5.0E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS01760 a63ede92fcb483882b418fccc3fca112 895 Gene3D G3DSA:3.40.50.300 21 147 2.0E-22 T 29-03-2018 MC49_RS01760 a63ede92fcb483882b418fccc3fca112 895 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 22 230 8.0E-96 T 29-03-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 MC49_RS01760 a63ede92fcb483882b418fccc3fca112 895 Pfam PF13493 Domain of unknown function (DUF4118) 403 507 1.3E-27 T 29-03-2018 IPR025201 Sensor protein KdpD, transmembrane domain MC49_RS01760 a63ede92fcb483882b418fccc3fca112 895 Gene3D G3DSA:3.30.565.10 725 884 1.8E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS01760 a63ede92fcb483882b418fccc3fca112 895 Gene3D G3DSA:1.10.287.130 654 724 7.5E-11 T 29-03-2018 MC49_RS01760 a63ede92fcb483882b418fccc3fca112 895 Gene3D G3DSA:3.40.50.620 234 379 9.7E-6 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS01760 a63ede92fcb483882b418fccc3fca112 895 Gene3D G3DSA:3.30.450.40 500 653 1.3E-7 T 29-03-2018 IPR029016 GAF domain-like MC49_RS01760 a63ede92fcb483882b418fccc3fca112 895 Pfam PF00512 His Kinase A (phospho-acceptor) domain 665 730 5.6E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS01760 a63ede92fcb483882b418fccc3fca112 895 Gene3D G3DSA:1.20.120.620 401 499 3.7E-24 T 29-03-2018 MC49_RS01760 a63ede92fcb483882b418fccc3fca112 895 SUPERFAMILY SSF47384 658 731 5.49E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS01760 a63ede92fcb483882b418fccc3fca112 895 SMART SM00387 774 884 4.3E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS01760 a63ede92fcb483882b418fccc3fca112 895 SMART SM00388 663 730 2.0E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS01760 a63ede92fcb483882b418fccc3fca112 895 Pfam PF13492 GAF domain 570 644 4.1E-6 T 29-03-2018 IPR003018 GAF domain GO:0005515 MC49_RS01760 a63ede92fcb483882b418fccc3fca112 895 SUPERFAMILY SSF55874 719 883 1.57E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS01760 a63ede92fcb483882b418fccc3fca112 895 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 777 882 3.2E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS08970 3889635373b0ae71b9371bc33df9834c 534 Pfam PF07731 Multicopper oxidase 424 533 6.2E-24 T 29-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 MC49_RS08970 3889635373b0ae71b9371bc33df9834c 534 SUPERFAMILY SSF49503 377 402 5.23E-32 T 29-03-2018 IPR008972 Cupredoxin MC49_RS08970 3889635373b0ae71b9371bc33df9834c 534 SUPERFAMILY SSF49503 174 290 5.23E-32 T 29-03-2018 IPR008972 Cupredoxin MC49_RS08970 3889635373b0ae71b9371bc33df9834c 534 SUPERFAMILY SSF49503 419 532 1.77E-26 T 29-03-2018 IPR008972 Cupredoxin MC49_RS08970 3889635373b0ae71b9371bc33df9834c 534 Gene3D G3DSA:2.60.40.420 30 171 5.1E-33 T 29-03-2018 IPR008972 Cupredoxin MC49_RS08970 3889635373b0ae71b9371bc33df9834c 534 Pfam PF07732 Multicopper oxidase 53 168 5.3E-32 T 29-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 MC49_RS08970 3889635373b0ae71b9371bc33df9834c 534 Pfam PF00394 Multicopper oxidase 220 299 1.9E-4 T 29-03-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 MC49_RS08970 3889635373b0ae71b9371bc33df9834c 534 SUPERFAMILY SSF49503 35 169 1.75E-35 T 29-03-2018 IPR008972 Cupredoxin MC49_RS08970 3889635373b0ae71b9371bc33df9834c 534 Gene3D G3DSA:2.60.40.420 172 415 1.0E-29 T 29-03-2018 IPR008972 Cupredoxin MC49_RS08970 3889635373b0ae71b9371bc33df9834c 534 Gene3D G3DSA:2.60.40.420 418 534 1.0E-26 T 29-03-2018 IPR008972 Cupredoxin MC49_RS08970 3889635373b0ae71b9371bc33df9834c 534 ProSitePatterns PS00080 Multicopper oxidases signature 2. 515 526 - T 29-03-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 MC49_RS07640 5aef1563c17696f146aa26b9a5c9ad27 1075 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MC49_RS07640 5aef1563c17696f146aa26b9a5c9ad27 1075 SUPERFAMILY SSF52440 557 676 1.06E-49 T 29-03-2018 IPR016185 Pre-ATP-grasp domain MC49_RS07640 5aef1563c17696f146aa26b9a5c9ad27 1075 SUPERFAMILY SSF52335 938 1071 1.01E-34 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain MC49_RS07640 5aef1563c17696f146aa26b9a5c9ad27 1075 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 674 876 2.6E-38 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MC49_RS07640 5aef1563c17696f146aa26b9a5c9ad27 1075 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 4.7E-76 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MC49_RS07640 5aef1563c17696f146aa26b9a5c9ad27 1075 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1068 13.362 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MC49_RS07640 5aef1563c17696f146aa26b9a5c9ad27 1075 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 710 724 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MC49_RS07640 5aef1563c17696f146aa26b9a5c9ad27 1075 SMART SM01096 424 547 2.6E-69 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MC49_RS07640 5aef1563c17696f146aa26b9a5c9ad27 1075 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MC49_RS07640 5aef1563c17696f146aa26b9a5c9ad27 1075 SMART SM00851 956 1042 6.7E-32 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain MC49_RS07640 5aef1563c17696f146aa26b9a5c9ad27 1075 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 3 1049 0.0 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MC49_RS07640 5aef1563c17696f146aa26b9a5c9ad27 1075 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 427 547 8.0E-38 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MC49_RS07640 5aef1563c17696f146aa26b9a5c9ad27 1075 SUPERFAMILY SSF52440 2 127 2.16E-49 T 29-03-2018 IPR016185 Pre-ATP-grasp domain MC49_RS07640 5aef1563c17696f146aa26b9a5c9ad27 1075 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1063 13.138 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MC49_RS07640 5aef1563c17696f146aa26b9a5c9ad27 1075 SUPERFAMILY SSF56059 128 401 1.17E-108 T 29-03-2018 MC49_RS07640 5aef1563c17696f146aa26b9a5c9ad27 1075 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 839 846 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MC49_RS07640 5aef1563c17696f146aa26b9a5c9ad27 1075 Gene3D G3DSA:3.40.50.1380 928 1054 7.3E-30 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain MC49_RS07640 5aef1563c17696f146aa26b9a5c9ad27 1075 Gene3D G3DSA:3.30.1490.20 656 745 1.2E-23 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MC49_RS07640 5aef1563c17696f146aa26b9a5c9ad27 1075 Gene3D G3DSA:3.40.50.20 539 655 1.6E-63 T 29-03-2018 MC49_RS07640 5aef1563c17696f146aa26b9a5c9ad27 1075 Pfam PF02142 MGS-like domain 957 1041 1.7E-18 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain MC49_RS07640 5aef1563c17696f146aa26b9a5c9ad27 1075 Gene3D G3DSA:3.40.50.20 4 109 1.8E-39 T 29-03-2018 MC49_RS07640 5aef1563c17696f146aa26b9a5c9ad27 1075 SUPERFAMILY SSF56059 674 934 4.77E-106 T 29-03-2018 MC49_RS07640 5aef1563c17696f146aa26b9a5c9ad27 1075 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 380 398 6.4E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MC49_RS07640 5aef1563c17696f146aa26b9a5c9ad27 1075 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 6.4E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MC49_RS07640 5aef1563c17696f146aa26b9a5c9ad27 1075 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 6.4E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MC49_RS07640 5aef1563c17696f146aa26b9a5c9ad27 1075 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 6.4E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MC49_RS07640 5aef1563c17696f146aa26b9a5c9ad27 1075 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 6.4E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MC49_RS07640 5aef1563c17696f146aa26b9a5c9ad27 1075 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 6.4E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MC49_RS07640 5aef1563c17696f146aa26b9a5c9ad27 1075 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 6.4E-64 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MC49_RS07640 5aef1563c17696f146aa26b9a5c9ad27 1075 Gene3D G3DSA:1.10.1030.10 404 538 2.8E-51 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MC49_RS07640 5aef1563c17696f146aa26b9a5c9ad27 1075 Gene3D G3DSA:3.30.470.20 746 927 2.1E-44 T 29-03-2018 MC49_RS07640 5aef1563c17696f146aa26b9a5c9ad27 1075 SUPERFAMILY SSF48108 396 554 1.96E-51 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MC49_RS07640 5aef1563c17696f146aa26b9a5c9ad27 1075 Gene3D G3DSA:3.30.470.20 119 403 8.8E-65 T 29-03-2018 MC49_RS03375 8ccab062b0d256d56a31f9d0822ed20c 910 SUPERFAMILY SSF50447 812 908 1.28E-33 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain MC49_RS03375 8ccab062b0d256d56a31f9d0822ed20c 910 Gene3D G3DSA:3.40.50.10050 722 789 3.7E-26 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 MC49_RS03375 8ccab062b0d256d56a31f9d0822ed20c 910 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 4 50 1.5E-8 T 29-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal MC49_RS03375 8ccab062b0d256d56a31f9d0822ed20c 910 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 334 384 2.7E-15 T 29-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal MC49_RS03375 8ccab062b0d256d56a31f9d0822ed20c 910 SUPERFAMILY SSF50447 585 665 7.07E-23 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain MC49_RS03375 8ccab062b0d256d56a31f9d0822ed20c 910 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 908 17.597 T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 MC49_RS03375 8ccab062b0d256d56a31f9d0822ed20c 910 SUPERFAMILY SSF46955 3 49 2.75E-11 T 29-03-2018 IPR009061 Putative DNA-binding domain MC49_RS03375 8ccab062b0d256d56a31f9d0822ed20c 910 ProSitePatterns PS01176 Initiation factor 2 signature. 861 883 - T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 MC49_RS03375 8ccab062b0d256d56a31f9d0822ed20c 910 Pfam PF11987 Translation-initiation factor 2 695 800 4.0E-37 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 MC49_RS03375 8ccab062b0d256d56a31f9d0822ed20c 910 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 326 910 4.9E-287 T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 MC49_RS03375 8ccab062b0d256d56a31f9d0822ed20c 910 Gene3D G3DSA:2.40.30.10 811 909 5.6E-31 T 29-03-2018 MC49_RS03375 8ccab062b0d256d56a31f9d0822ed20c 910 Pfam PF08364 Bacterial translation initiation factor IF-2 associated region 58 96 4.8E-15 T 29-03-2018 IPR013575 Initiation factor 2 associated domain, bacterial MC49_RS03375 8ccab062b0d256d56a31f9d0822ed20c 910 SUPERFAMILY SSF52540 405 578 1.54E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS03375 8ccab062b0d256d56a31f9d0822ed20c 910 Gene3D G3DSA:2.40.30.10 583 721 2.4E-29 T 29-03-2018 MC49_RS03375 8ccab062b0d256d56a31f9d0822ed20c 910 Gene3D G3DSA:3.30.56.50 336 377 5.4E-10 T 29-03-2018 MC49_RS03375 8ccab062b0d256d56a31f9d0822ed20c 910 Gene3D G3DSA:3.30.56.50 4 44 5.5E-9 T 29-03-2018 MC49_RS03375 8ccab062b0d256d56a31f9d0822ed20c 910 Gene3D G3DSA:3.40.50.300 405 580 3.8E-40 T 29-03-2018 MC49_RS03375 8ccab062b0d256d56a31f9d0822ed20c 910 Pfam PF00009 Elongation factor Tu GTP binding domain 415 571 2.8E-35 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS03375 8ccab062b0d256d56a31f9d0822ed20c 910 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 414 569 2.6E-33 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MC49_RS03375 8ccab062b0d256d56a31f9d0822ed20c 910 SUPERFAMILY SSF52156 688 817 5.89E-38 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 MC49_RS15930 f7de48c7501d0301ccbec96d70bfd663 661 Hamap MF_01166 Bifunctional polymyxin resistance protein ArnA [arnA]. 1 660 64.643 T 29-03-2018 IPR021168 Bifunctional polymyxin resistance protein, ArnA GO:0016742|GO:0055114 KEGG: 00072+1.1.1.30|KEGG: 00520+2.1.2.13+1.1.1.305|KEGG: 00650+1.1.1.30 MC49_RS15930 f7de48c7501d0301ccbec96d70bfd663 661 SUPERFAMILY SSF53328 1 200 1.7E-56 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MC49_RS15930 f7de48c7501d0301ccbec96d70bfd663 661 Pfam PF00551 Formyl transferase 17 176 4.6E-27 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MC49_RS15930 f7de48c7501d0301ccbec96d70bfd663 661 SUPERFAMILY SSF50486 204 302 1.11E-26 T 29-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 MC49_RS15930 f7de48c7501d0301ccbec96d70bfd663 661 Pfam PF02911 Formyl transferase, C-terminal domain 204 283 5.9E-20 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MC49_RS15930 f7de48c7501d0301ccbec96d70bfd663 661 Gene3D G3DSA:3.10.25.10 203 303 2.1E-23 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MC49_RS15930 f7de48c7501d0301ccbec96d70bfd663 661 Pfam PF01370 NAD dependent epimerase/dehydratase family 318 566 4.5E-45 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MC49_RS15930 f7de48c7501d0301ccbec96d70bfd663 661 PIRSF PIRSF036506 1 660 0.0 T 29-03-2018 IPR021168 Bifunctional polymyxin resistance protein, ArnA GO:0016742|GO:0055114 KEGG: 00072+1.1.1.30|KEGG: 00520+2.1.2.13+1.1.1.305|KEGG: 00650+1.1.1.30 MC49_RS15930 f7de48c7501d0301ccbec96d70bfd663 661 Gene3D G3DSA:3.40.50.720 314 656 4.3E-47 T 29-03-2018 MC49_RS15930 f7de48c7501d0301ccbec96d70bfd663 661 SUPERFAMILY SSF51735 316 650 1.58E-71 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS15930 f7de48c7501d0301ccbec96d70bfd663 661 Gene3D G3DSA:3.40.50.170 1 200 6.1E-50 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MC49_RS09255 1e8dd0a15f6426a8b9f91406fe4bed9f 387 PIRSF PIRSF000724 1 387 1.8E-133 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS09255 1e8dd0a15f6426a8b9f91406fe4bed9f 387 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 383 39.312 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS09255 1e8dd0a15f6426a8b9f91406fe4bed9f 387 Gene3D G3DSA:3.40.50.1260 175 371 1.0E-75 T 29-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS09255 1e8dd0a15f6426a8b9f91406fe4bed9f 387 PRINTS PR00477 Phosphoglycerate kinase family signature 336 347 1.8E-82 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS09255 1e8dd0a15f6426a8b9f91406fe4bed9f 387 PRINTS PR00477 Phosphoglycerate kinase family signature 359 376 1.8E-82 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS09255 1e8dd0a15f6426a8b9f91406fe4bed9f 387 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 1.8E-82 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS09255 1e8dd0a15f6426a8b9f91406fe4bed9f 387 PRINTS PR00477 Phosphoglycerate kinase family signature 132 154 1.8E-82 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS09255 1e8dd0a15f6426a8b9f91406fe4bed9f 387 PRINTS PR00477 Phosphoglycerate kinase family signature 163 185 1.8E-82 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS09255 1e8dd0a15f6426a8b9f91406fe4bed9f 387 PRINTS PR00477 Phosphoglycerate kinase family signature 186 205 1.8E-82 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS09255 1e8dd0a15f6426a8b9f91406fe4bed9f 387 PRINTS PR00477 Phosphoglycerate kinase family signature 104 119 1.8E-82 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS09255 1e8dd0a15f6426a8b9f91406fe4bed9f 387 PRINTS PR00477 Phosphoglycerate kinase family signature 303 328 1.8E-82 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS09255 1e8dd0a15f6426a8b9f91406fe4bed9f 387 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 1.8E-82 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS09255 1e8dd0a15f6426a8b9f91406fe4bed9f 387 Pfam PF00162 Phosphoglycerate kinase 6 373 8.2E-139 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS09255 1e8dd0a15f6426a8b9f91406fe4bed9f 387 Gene3D G3DSA:3.40.50.1260 3 174 6.5E-61 T 29-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS09255 1e8dd0a15f6426a8b9f91406fe4bed9f 387 SUPERFAMILY SSF53748 3 383 1.3E-144 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS07695 5fbaac5806fdb7840e8067a34f96d985 475 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 342 408 1.0E-17 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MC49_RS07695 5fbaac5806fdb7840e8067a34f96d985 475 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 51 74 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MC49_RS07695 5fbaac5806fdb7840e8067a34f96d985 475 SUPERFAMILY SSF53613 12 310 1.87E-58 T 29-03-2018 IPR029056 Ribokinase-like MC49_RS07695 5fbaac5806fdb7840e8067a34f96d985 475 TIGRFAM TIGR02198 rfaE_dom_I: bifunctional protein RfaE, domain I 5 312 7.7E-126 T 29-03-2018 IPR011913 RfaE bifunctional protein, domain I GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 MC49_RS07695 5fbaac5806fdb7840e8067a34f96d985 475 Pfam PF00294 pfkB family carbohydrate kinase 13 305 1.8E-51 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB MC49_RS07695 5fbaac5806fdb7840e8067a34f96d985 475 Pfam PF01467 Cytidylyltransferase-like 345 469 1.2E-15 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MC49_RS07695 5fbaac5806fdb7840e8067a34f96d985 475 Gene3D G3DSA:3.40.1190.20 2 310 2.2E-57 T 29-03-2018 IPR029056 Ribokinase-like MC49_RS07695 5fbaac5806fdb7840e8067a34f96d985 475 TIGRFAM TIGR02199 rfaE_dom_II: bifunctional protein RfaE, domain II 332 473 5.3E-64 T 29-03-2018 IPR011914 RfaE bifunctional protein, domain II GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 MC49_RS07695 5fbaac5806fdb7840e8067a34f96d985 475 Hamap MF_01603 Bifunctional protein HldE [hldE]. 4 474 43.409 T 29-03-2018 IPR023030 Bifunctional protein HldE GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 MC49_RS07695 5fbaac5806fdb7840e8067a34f96d985 475 Gene3D G3DSA:3.40.50.620 321 475 7.3E-28 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS07695 5fbaac5806fdb7840e8067a34f96d985 475 SUPERFAMILY SSF52374 340 471 2.48E-23 T 29-03-2018 MC49_RS12120 be416a6b0a1b7596d2234090aac34ff5 107 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 103 2.1E-23 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MC49_RS12120 be416a6b0a1b7596d2234090aac34ff5 107 TIGRFAM TIGR02011 IscA: iron-sulfur cluster assembly protein IscA 4 107 4.8E-58 T 29-03-2018 IPR011302 Iron-binding protein IscA, proteobacteria GO:0005506|GO:0051536|GO:0097428 MC49_RS12120 be416a6b0a1b7596d2234090aac34ff5 107 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 88 105 - T 29-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 MC49_RS12120 be416a6b0a1b7596d2234090aac34ff5 107 Gene3D G3DSA:2.60.300.12 2 107 1.4E-37 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MC49_RS12120 be416a6b0a1b7596d2234090aac34ff5 107 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 3 107 5.2E-37 T 29-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 MC49_RS12120 be416a6b0a1b7596d2234090aac34ff5 107 Hamap MF_01429 Iron-binding protein IscA [iscA]. 1 107 38.009 T 29-03-2018 IPR011302 Iron-binding protein IscA, proteobacteria GO:0005506|GO:0051536|GO:0097428 MC49_RS12120 be416a6b0a1b7596d2234090aac34ff5 107 SUPERFAMILY SSF89360 1 95 6.02E-33 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MC49_RS07690 ceb227dd1a9dea9cd7039677a7a5fb60 942 Gene3D G3DSA:1.10.4050.10 515 634 3.5E-23 T 29-03-2018 MC49_RS07690 ceb227dd1a9dea9cd7039677a7a5fb60 942 Gene3D G3DSA:1.10.4050.10 4 106 1.0E-14 T 29-03-2018 MC49_RS07690 ceb227dd1a9dea9cd7039677a7a5fb60 942 SUPERFAMILY SSF81593 285 434 6.43E-41 T 29-03-2018 MC49_RS07690 ceb227dd1a9dea9cd7039677a7a5fb60 942 Gene3D G3DSA:3.30.460.10 109 282 3.2E-58 T 29-03-2018 MC49_RS07690 ceb227dd1a9dea9cd7039677a7a5fb60 942 Gene3D G3DSA:3.30.460.10 635 808 1.6E-59 T 29-03-2018 MC49_RS07690 ceb227dd1a9dea9cd7039677a7a5fb60 942 Hamap MF_00802 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme [glnE]. 25 942 19.42 T 29-03-2018 IPR023057 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme GO:0008882 MC49_RS07690 ceb227dd1a9dea9cd7039677a7a5fb60 942 Pfam PF08335 GlnD PII-uridylyltransferase 822 916 2.1E-9 T 29-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 MC49_RS07690 ceb227dd1a9dea9cd7039677a7a5fb60 942 Pfam PF08335 GlnD PII-uridylyltransferase 295 434 1.8E-40 T 29-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 MC49_RS07690 ceb227dd1a9dea9cd7039677a7a5fb60 942 Gene3D G3DSA:1.20.120.330 809 942 9.1E-35 T 29-03-2018 MC49_RS07690 ceb227dd1a9dea9cd7039677a7a5fb60 942 SUPERFAMILY SSF81593 812 940 6.43E-32 T 29-03-2018 MC49_RS07690 ceb227dd1a9dea9cd7039677a7a5fb60 942 SUPERFAMILY SSF81301 28 284 2.29E-88 T 29-03-2018 MC49_RS07690 ceb227dd1a9dea9cd7039677a7a5fb60 942 Gene3D G3DSA:1.20.120.330 283 438 1.1E-45 T 29-03-2018 MC49_RS07690 ceb227dd1a9dea9cd7039677a7a5fb60 942 SUPERFAMILY SSF81301 522 811 2.56E-89 T 29-03-2018 MC49_RS07690 ceb227dd1a9dea9cd7039677a7a5fb60 942 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 550 801 5.3E-97 T 29-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 MC49_RS07690 ceb227dd1a9dea9cd7039677a7a5fb60 942 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 32 273 5.0E-93 T 29-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 MC49_RS07430 6addc42f7ed9bc2bde870a5d477e0e6e 388 Pfam PF07885 Ion channel 148 224 9.3E-12 T 29-03-2018 IPR013099 Potassium channel domain MC49_RS07430 6addc42f7ed9bc2bde870a5d477e0e6e 388 Gene3D G3DSA:1.10.287.70 7 226 1.0E-11 T 29-03-2018 MC49_RS07430 6addc42f7ed9bc2bde870a5d477e0e6e 388 SUPERFAMILY SSF81324 66 96 1.57E-16 T 29-03-2018 MC49_RS07430 6addc42f7ed9bc2bde870a5d477e0e6e 388 SUPERFAMILY SSF81324 166 263 1.57E-16 T 29-03-2018 MC49_RS07430 6addc42f7ed9bc2bde870a5d477e0e6e 388 SUPERFAMILY SSF51735 238 375 3.31E-21 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS07430 6addc42f7ed9bc2bde870a5d477e0e6e 388 Gene3D G3DSA:3.40.50.720 232 356 6.6E-18 T 29-03-2018 MC49_RS07430 6addc42f7ed9bc2bde870a5d477e0e6e 388 Pfam PF02254 TrkA-N domain 243 356 3.7E-17 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MC49_RS09400 cf2fa5f334648e4adacf5561c27a4a7b 307 Gene3D G3DSA:3.40.190.10 178 267 5.7E-25 T 29-03-2018 MC49_RS09400 cf2fa5f334648e4adacf5561c27a4a7b 307 Gene3D G3DSA:3.40.190.10 93 177 1.4E-12 T 29-03-2018 MC49_RS09400 cf2fa5f334648e4adacf5561c27a4a7b 307 SUPERFAMILY SSF53850 92 301 2.79E-44 T 29-03-2018 MC49_RS09400 cf2fa5f334648e4adacf5561c27a4a7b 307 Pfam PF03466 LysR substrate binding domain 92 298 1.6E-41 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS09400 cf2fa5f334648e4adacf5561c27a4a7b 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 4.1E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS09400 cf2fa5f334648e4adacf5561c27a4a7b 307 SUPERFAMILY SSF46785 9 91 1.15E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS09400 cf2fa5f334648e4adacf5561c27a4a7b 307 Gene3D G3DSA:1.10.10.10 7 91 5.2E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS05780 db9b98cc3a753b0b3a81cb04f6a5c789 165 PIRSF PIRSF034445 1 156 1.3E-28 T 29-03-2018 IPR012899 LTXXQ motif family protein GO:0042597 MC49_RS05780 db9b98cc3a753b0b3a81cb04f6a5c789 165 Pfam PF07813 LTXXQ motif family protein 53 146 3.0E-17 T 29-03-2018 IPR012899 LTXXQ motif family protein GO:0042597 MC49_RS16605 5448ca5bb0faf906cace51b9c63ae7ff 505 Pfam PF13522 Glutamine amidotransferase domain 65 210 6.6E-15 T 29-03-2018 MC49_RS16605 5448ca5bb0faf906cace51b9c63ae7ff 505 PIRSF PIRSF000485 1 483 1.3E-164 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 MC49_RS16605 5448ca5bb0faf906cace51b9c63ae7ff 505 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 466 44.827 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 MC49_RS16605 5448ca5bb0faf906cace51b9c63ae7ff 505 SUPERFAMILY SSF56235 2 259 4.2E-74 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MC49_RS16605 5448ca5bb0faf906cace51b9c63ae7ff 505 Gene3D G3DSA:3.60.20.10 2 259 5.9E-53 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MC49_RS16605 5448ca5bb0faf906cace51b9c63ae7ff 505 SUPERFAMILY SSF53271 252 485 7.34E-70 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like MC49_RS16605 5448ca5bb0faf906cace51b9c63ae7ff 505 Pfam PF00156 Phosphoribosyl transferase domain 282 395 2.3E-8 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MC49_RS16605 5448ca5bb0faf906cace51b9c63ae7ff 505 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 2 466 2.1E-158 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 MC49_RS16605 5448ca5bb0faf906cace51b9c63ae7ff 505 Gene3D G3DSA:3.40.50.2020 277 446 8.8E-35 T 29-03-2018 MC49_RS09560 de5b3e34108696d70fb6e002637106e1 358 SUPERFAMILY SSF53955 159 357 1.49E-38 T 29-03-2018 IPR023346 Lysozyme-like domain MC49_RS09560 de5b3e34108696d70fb6e002637106e1 358 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 213 241 - T 29-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 MC49_RS09560 de5b3e34108696d70fb6e002637106e1 358 Gene3D G3DSA:1.10.530.10 181 356 1.1E-38 T 29-03-2018 MC49_RS09560 de5b3e34108696d70fb6e002637106e1 358 Pfam PF11873 Domain of unknown function (DUF3393) 6 191 3.1E-75 T 29-03-2018 IPR024570 Murein transglycosylase-C, N-terminal MC49_RS09560 de5b3e34108696d70fb6e002637106e1 358 Hamap MF_01616 Membrane-bound lytic murein transglycosylase C [mltC]. 1 358 59.671 T 29-03-2018 IPR023664 Murein transglycosylase-C GO:0009279|GO:0016798|GO:0016998 MC49_RS09560 de5b3e34108696d70fb6e002637106e1 358 Pfam PF01464 Transglycosylase SLT domain 196 319 5.5E-34 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 MC49_RS18845 9c776c89a982059b93fa65024e719e41 634 SUPERFAMILY SSF50621 459 562 5.23E-6 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MC49_RS18845 9c776c89a982059b93fa65024e719e41 634 Gene3D G3DSA:3.20.20.10 84 343 8.9E-41 T 29-03-2018 IPR029066 PLP-binding barrel MC49_RS18845 9c776c89a982059b93fa65024e719e41 634 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 122 134 1.4E-19 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MC49_RS18845 9c776c89a982059b93fa65024e719e41 634 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 239 252 1.4E-19 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MC49_RS18845 9c776c89a982059b93fa65024e719e41 634 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 100 118 1.4E-19 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MC49_RS18845 9c776c89a982059b93fa65024e719e41 634 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 333 352 1.4E-19 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MC49_RS18845 9c776c89a982059b93fa65024e719e41 634 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 542 555 1.4E-19 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MC49_RS18845 9c776c89a982059b93fa65024e719e41 634 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 277 290 - T 29-03-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site MC49_RS18845 9c776c89a982059b93fa65024e719e41 634 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 76 343 2.0E-68 T 29-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 MC49_RS18845 9c776c89a982059b93fa65024e719e41 634 Hamap MF_01417 Biosynthetic arginine decarboxylase [speA]. 2 633 41.823 T 29-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MC49_RS18845 9c776c89a982059b93fa65024e719e41 634 TIGRFAM TIGR01273 speA: arginine decarboxylase 8 632 4.5E-264 T 29-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MC49_RS18845 9c776c89a982059b93fa65024e719e41 634 Gene3D G3DSA:2.40.37.10 2 83 9.5E-13 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MC49_RS18845 9c776c89a982059b93fa65024e719e41 634 Gene3D G3DSA:2.40.37.10 398 580 3.1E-60 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MC49_RS18845 9c776c89a982059b93fa65024e719e41 634 SUPERFAMILY SSF51419 68 345 2.43E-68 T 29-03-2018 IPR029066 PLP-binding barrel MC49_RS18845 9c776c89a982059b93fa65024e719e41 634 PRINTS PR01180 Arginine decarboxylase signature 464 485 2.8E-70 T 29-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MC49_RS18845 9c776c89a982059b93fa65024e719e41 634 PRINTS PR01180 Arginine decarboxylase signature 542 563 2.8E-70 T 29-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MC49_RS18845 9c776c89a982059b93fa65024e719e41 634 PRINTS PR01180 Arginine decarboxylase signature 323 340 2.8E-70 T 29-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MC49_RS18845 9c776c89a982059b93fa65024e719e41 634 PRINTS PR01180 Arginine decarboxylase signature 172 193 2.8E-70 T 29-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MC49_RS18845 9c776c89a982059b93fa65024e719e41 634 PRINTS PR01180 Arginine decarboxylase signature 92 106 2.8E-70 T 29-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MC49_RS18845 9c776c89a982059b93fa65024e719e41 634 PRINTS PR01180 Arginine decarboxylase signature 196 218 2.8E-70 T 29-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MC49_RS18845 9c776c89a982059b93fa65024e719e41 634 PRINTS PR01180 Arginine decarboxylase signature 489 514 2.8E-70 T 29-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MC49_RS18845 9c776c89a982059b93fa65024e719e41 634 PRINTS PR01180 Arginine decarboxylase signature 68 83 2.8E-70 T 29-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MC49_RS18845 9c776c89a982059b93fa65024e719e41 634 PRINTS PR01180 Arginine decarboxylase signature 146 161 2.8E-70 T 29-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MC49_RS18845 9c776c89a982059b93fa65024e719e41 634 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 100 118 - T 29-03-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site MC49_RS18845 9c776c89a982059b93fa65024e719e41 634 PIRSF PIRSF001336 3 634 4.1E-249 T 29-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MC49_RS11380 9536ed3748f91b25b96ac6e82c282a0f 722 Pfam PF00384 Molybdopterin oxidoreductase 61 488 3.3E-87 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS11380 9536ed3748f91b25b96ac6e82c282a0f 722 Gene3D G3DSA:3.40.50.740 259 533 9.4E-79 T 29-03-2018 MC49_RS11380 9536ed3748f91b25b96ac6e82c282a0f 722 SMART SM00926 1 54 7.0E-16 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS11380 9536ed3748f91b25b96ac6e82c282a0f 722 Gene3D G3DSA:3.40.228.10 168 258 2.2E-25 T 29-03-2018 MC49_RS11380 9536ed3748f91b25b96ac6e82c282a0f 722 Gene3D G3DSA:2.40.40.20 534 688 1.3E-36 T 29-03-2018 MC49_RS11380 9536ed3748f91b25b96ac6e82c282a0f 722 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 2 53 5.2E-13 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS11380 9536ed3748f91b25b96ac6e82c282a0f 722 SUPERFAMILY SSF53706 1 563 2.62E-192 T 29-03-2018 MC49_RS11380 9536ed3748f91b25b96ac6e82c282a0f 722 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 435 452 - T 29-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 MC49_RS11380 9536ed3748f91b25b96ac6e82c282a0f 722 Pfam PF01568 Molydopterin dinucleotide binding domain 576 683 1.3E-26 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 MC49_RS11380 9536ed3748f91b25b96ac6e82c282a0f 722 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 7 686 6.3E-274 T 29-03-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 MC49_RS11380 9536ed3748f91b25b96ac6e82c282a0f 722 Gene3D G3DSA:3.40.50.740 61 167 6.2E-22 T 29-03-2018 MC49_RS11380 9536ed3748f91b25b96ac6e82c282a0f 722 PIRSF PIRSF000144 540 692 63.0 T 29-03-2018 MC49_RS11380 9536ed3748f91b25b96ac6e82c282a0f 722 PIRSF PIRSF000144 53 448 1.2E-57 T 29-03-2018 MC49_RS11380 9536ed3748f91b25b96ac6e82c282a0f 722 Gene3D G3DSA:2.20.25.90 1 55 3.6E-16 T 29-03-2018 MC49_RS11380 9536ed3748f91b25b96ac6e82c282a0f 722 SUPERFAMILY SSF50692 566 703 8.5E-41 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain MC49_RS07475 37c9e99d02cc71923d910cdc87ec5b04 641 Gene3D G3DSA:1.25.20.10 24 385 1.6E-47 T 29-03-2018 MC49_RS07475 37c9e99d02cc71923d910cdc87ec5b04 641 Gene3D G3DSA:1.10.530.10 467 638 1.4E-38 T 29-03-2018 MC49_RS07475 37c9e99d02cc71923d910cdc87ec5b04 641 SUPERFAMILY SSF53955 473 626 3.56E-48 T 29-03-2018 IPR023346 Lysozyme-like domain MC49_RS07475 37c9e99d02cc71923d910cdc87ec5b04 641 Pfam PF14718 Soluble lytic murein transglycosylase L domain 400 466 1.7E-24 T 29-03-2018 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 MC49_RS07475 37c9e99d02cc71923d910cdc87ec5b04 641 Pfam PF01464 Transglycosylase SLT domain 480 590 8.9E-32 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 MC49_RS07475 37c9e99d02cc71923d910cdc87ec5b04 641 SUPERFAMILY SSF48435 24 471 1.57E-125 T 29-03-2018 IPR016026 Lytic transglycosylase, superhelical U-shaped and linker domain GO:0004553|GO:0042597 MC49_RS07475 37c9e99d02cc71923d910cdc87ec5b04 641 Gene3D G3DSA:1.10.1240.20 398 466 7.4E-19 T 29-03-2018 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 MC49_RS07475 37c9e99d02cc71923d910cdc87ec5b04 641 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 495 523 - T 29-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 MC49_RS08480 194a603a73b3195ee33b3790a5d6e69b 146 Hamap MF_00526 Glutamate mutase sigma subunit [glmS]. 1 137 36.162 T 29-03-2018 IPR006394 Glutamate mutase sigma subunit GO:0016866|GO:0019670 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 MC49_RS08480 194a603a73b3195ee33b3790a5d6e69b 146 Pfam PF02310 B12 binding domain 5 95 1.8E-13 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 MC49_RS08480 194a603a73b3195ee33b3790a5d6e69b 146 TIGRFAM TIGR01501 MthylAspMutase: methylaspartate mutase, S subunit 3 135 7.2E-67 T 29-03-2018 IPR006394 Glutamate mutase sigma subunit GO:0016866|GO:0019670 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 MC49_RS08480 194a603a73b3195ee33b3790a5d6e69b 146 Gene3D G3DSA:3.40.50.280 1 137 7.4E-28 T 29-03-2018 MC49_RS08480 194a603a73b3195ee33b3790a5d6e69b 146 SUPERFAMILY SSF52242 3 136 1.11E-32 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 MC49_RS13985 bd6641cd82b984e07be8e7337b168879 399 Gene3D G3DSA:1.20.1250.20 198 392 1.3E-20 T 29-03-2018 MC49_RS13985 bd6641cd82b984e07be8e7337b168879 399 Pfam PF07690 Major Facilitator Superfamily 21 210 9.5E-22 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS13985 bd6641cd82b984e07be8e7337b168879 399 Pfam PF07690 Major Facilitator Superfamily 221 390 2.3E-13 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS13985 bd6641cd82b984e07be8e7337b168879 399 Gene3D G3DSA:1.20.1250.20 5 195 2.2E-23 T 29-03-2018 MC49_RS13985 bd6641cd82b984e07be8e7337b168879 399 Hamap MF_01529 Multidrug resistance protein MdtH [mdtH]. 1 399 39.624 T 29-03-2018 IPR022855 Multidrug resistance protein MdtH MC49_RS13985 bd6641cd82b984e07be8e7337b168879 399 SUPERFAMILY SSF103473 14 390 1.44E-51 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS14560 595ce78a73d90954fa7cc25694e49d29 465 SUPERFAMILY SSF51556 82 380 6.41E-83 T 29-03-2018 IPR032466 Metal-dependent hydrolase MC49_RS14560 595ce78a73d90954fa7cc25694e49d29 465 Gene3D G3DSA:3.20.20.140 97 397 2.4E-55 T 29-03-2018 MC49_RS14560 595ce78a73d90954fa7cc25694e49d29 465 Gene3D G3DSA:2.30.40.10 13 96 3.7E-20 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS14560 595ce78a73d90954fa7cc25694e49d29 465 SUPERFAMILY SSF51338 25 82 1.98E-36 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS14560 595ce78a73d90954fa7cc25694e49d29 465 SUPERFAMILY SSF51338 379 454 1.98E-36 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS14560 595ce78a73d90954fa7cc25694e49d29 465 Pfam PF01979 Amidohydrolase family 79 427 3.3E-63 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MC49_RS16715 fffe4bc6fc714bce6ea035674655db9a 309 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 15 303 1.2E-98 T 29-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 MC49_RS16715 fffe4bc6fc714bce6ea035674655db9a 309 Hamap MF_02125 50S ribosomal protein L3 glutamine methyltransferase [prmB]. 6 300 53.168 T 29-03-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 MC49_RS16715 fffe4bc6fc714bce6ea035674655db9a 309 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 204 210 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MC49_RS16715 fffe4bc6fc714bce6ea035674655db9a 309 SUPERFAMILY SSF53335 16 293 1.63E-50 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS16715 fffe4bc6fc714bce6ea035674655db9a 309 Pfam PF05175 Methyltransferase small domain 130 215 1.5E-15 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 MC49_RS16715 fffe4bc6fc714bce6ea035674655db9a 309 TIGRFAM TIGR03533 L3_gln_methyl: protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 13 295 8.3E-134 T 29-03-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 MC49_RS16715 fffe4bc6fc714bce6ea035674655db9a 309 Gene3D G3DSA:3.40.50.150 102 279 9.3E-37 T 29-03-2018 MC49_RS16715 fffe4bc6fc714bce6ea035674655db9a 309 Gene3D G3DSA:1.10.8.10 14 101 1.2E-10 T 29-03-2018 MC49_RS16715 fffe4bc6fc714bce6ea035674655db9a 309 PIRSF PIRSF037167 2 307 5.2E-145 T 29-03-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 MC49_RS12195 a94085adb305a1251af1b82662697d63 426 Gene3D G3DSA:3.40.50.800 328 425 1.5E-17 T 29-03-2018 IPR004154 Anticodon-binding MC49_RS12195 a94085adb305a1251af1b82662697d63 426 Pfam PF13393 Histidyl-tRNA synthetase 10 312 7.5E-44 T 29-03-2018 MC49_RS12195 a94085adb305a1251af1b82662697d63 426 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 6 413 9.4E-157 T 29-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 MC49_RS12195 a94085adb305a1251af1b82662697d63 426 Pfam PF03129 Anticodon binding domain 345 423 2.9E-11 T 29-03-2018 IPR004154 Anticodon-binding MC49_RS12195 a94085adb305a1251af1b82662697d63 426 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 3 423 33.608 T 29-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 MC49_RS12195 a94085adb305a1251af1b82662697d63 426 PIRSF PIRSF001549 1 425 3.9E-127 T 29-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 MC49_RS12195 a94085adb305a1251af1b82662697d63 426 SUPERFAMILY SSF52954 331 425 9.0E-24 T 29-03-2018 IPR004154 Anticodon-binding MC49_RS12195 a94085adb305a1251af1b82662697d63 426 Gene3D G3DSA:3.30.930.10 1 324 1.2E-73 T 29-03-2018 MC49_RS12195 a94085adb305a1251af1b82662697d63 426 SUPERFAMILY SSF55681 4 321 1.65E-101 T 29-03-2018 MC49_RS18460 5ffb4c71297deb64109fa6252165cfd7 439 SUPERFAMILY SSF55920 175 434 1.23E-87 T 29-03-2018 IPR000994 Peptidase M24 MC49_RS18460 5ffb4c71297deb64109fa6252165cfd7 439 PRINTS PR00599 Methionine aminopeptidase-1 signature 370 382 1.1E-6 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MC49_RS18460 5ffb4c71297deb64109fa6252165cfd7 439 PRINTS PR00599 Methionine aminopeptidase-1 signature 253 269 1.1E-6 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MC49_RS18460 5ffb4c71297deb64109fa6252165cfd7 439 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 348 360 - T 29-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site MC49_RS18460 5ffb4c71297deb64109fa6252165cfd7 439 SUPERFAMILY SSF53092 1 174 2.62E-52 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal MC49_RS18460 5ffb4c71297deb64109fa6252165cfd7 439 Pfam PF05195 Aminopeptidase P, N-terminal domain 6 126 1.6E-34 T 29-03-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 MC49_RS18460 5ffb4c71297deb64109fa6252165cfd7 439 Gene3D G3DSA:3.40.350.10 1 171 3.1E-46 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal MC49_RS18460 5ffb4c71297deb64109fa6252165cfd7 439 SMART SM01011 1 136 1.6E-56 T 29-03-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 MC49_RS18460 5ffb4c71297deb64109fa6252165cfd7 439 Pfam PF00557 Metallopeptidase family M24 181 411 5.8E-65 T 29-03-2018 IPR000994 Peptidase M24 MC49_RS18460 5ffb4c71297deb64109fa6252165cfd7 439 Gene3D G3DSA:3.90.230.10 172 438 4.6E-88 T 29-03-2018 MC49_RS07615 51cb79aac47e54ad2d38cebbde8dc9b9 143 SUPERFAMILY SSF54534 3 141 2.55E-32 T 29-03-2018 MC49_RS07615 51cb79aac47e54ad2d38cebbde8dc9b9 143 Gene3D G3DSA:3.10.50.40 1 143 1.4E-18 T 29-03-2018 MC49_RS07615 51cb79aac47e54ad2d38cebbde8dc9b9 143 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 4 100 4.9E-12 T 29-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain MC49_RS07845 9e2e8503610444e2cacfc49189a9bab1 177 PRINTS PR00502 NUDIX hydrolase family signature 47 62 9.6E-8 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MC49_RS07845 9e2e8503610444e2cacfc49189a9bab1 177 PRINTS PR00502 NUDIX hydrolase family signature 33 47 9.6E-8 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MC49_RS07845 9e2e8503610444e2cacfc49189a9bab1 177 Gene3D G3DSA:3.90.79.10 1 164 6.3E-37 T 29-03-2018 MC49_RS07845 9e2e8503610444e2cacfc49189a9bab1 177 Pfam PF00293 NUDIX domain 7 145 7.3E-29 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MC49_RS07845 9e2e8503610444e2cacfc49189a9bab1 177 Hamap MF_00298 RNA pyrophosphohydrolase [rppH]. 1 156 37.816 T 29-03-2018 IPR022927 RNA pyrophosphohydrolase RppH MC49_RS07845 9e2e8503610444e2cacfc49189a9bab1 177 SUPERFAMILY SSF55811 6 151 1.15E-33 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MC49_RS07845 9e2e8503610444e2cacfc49189a9bab1 177 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MC49_RS01830 7aa39cc467480e2a0a6fe0892a007680 422 Pfam PF02447 GntP family permease 10 415 1.4E-24 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 MC49_RS16945 78229dc28a465a725c16abfab7102fdd 209 Gene3D G3DSA:1.10.3890.10 4 207 7.9E-75 T 29-03-2018 IPR007451 Uncharacterised protein family UPF0274 MC49_RS16945 78229dc28a465a725c16abfab7102fdd 209 SUPERFAMILY SSF101322 1 207 2.88E-76 T 29-03-2018 IPR007451 Uncharacterised protein family UPF0274 MC49_RS16945 78229dc28a465a725c16abfab7102fdd 209 Hamap MF_00695 High frequency lysogenization protein HflD [hflD]. 1 207 35.595 T 29-03-2018 IPR007451 Uncharacterised protein family UPF0274 MC49_RS16945 78229dc28a465a725c16abfab7102fdd 209 ProDom PD037115 UPF0274 YCFC HI0638 METABOLISM UNCHARACTERIZED VV1342 PURINE INVOLVED SO2634 HFLD 9 205 8.0E-56 T 29-03-2018 IPR007451 Uncharacterised protein family UPF0274 MC49_RS16945 78229dc28a465a725c16abfab7102fdd 209 Pfam PF04356 Protein of unknown function (DUF489) 7 199 2.8E-71 T 29-03-2018 IPR007451 Uncharacterised protein family UPF0274 MC49_RS17085 3405c607257990e16f4613bae06aa92f 414 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 4 412 4.3E-187 T 29-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 MC49_RS17085 3405c607257990e16f4613bae06aa92f 414 SMART SM00825 Beta-ketoacyl synthase 6 414 1.2E-16 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MC49_RS17085 3405c607257990e16f4613bae06aa92f 414 Gene3D G3DSA:3.40.47.10 6 261 2.8E-82 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MC49_RS17085 3405c607257990e16f4613bae06aa92f 414 SUPERFAMILY SSF53901 216 413 1.88E-69 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MC49_RS17085 3405c607257990e16f4613bae06aa92f 414 SUPERFAMILY SSF53901 4 253 7.27E-78 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MC49_RS17085 3405c607257990e16f4613bae06aa92f 414 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 156 172 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site MC49_RS17085 3405c607257990e16f4613bae06aa92f 414 Gene3D G3DSA:3.40.47.10 264 414 1.4E-49 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MC49_RS17085 3405c607257990e16f4613bae06aa92f 414 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 248 4.4E-63 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MC49_RS17085 3405c607257990e16f4613bae06aa92f 414 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 256 369 3.2E-38 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MC49_RS17085 3405c607257990e16f4613bae06aa92f 414 PIRSF PIRSF000447 1 414 5.1E-193 T 29-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 MC49_RS16160 55ad971bbb804d2ee1d9fc5ed8b07c4b 444 Gene3D G3DSA:2.160.20.10 25 343 3.6E-32 T 29-03-2018 IPR012334 Pectin lyase fold MC49_RS16160 55ad971bbb804d2ee1d9fc5ed8b07c4b 444 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 65 141 6.9E-17 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal MC49_RS16160 55ad971bbb804d2ee1d9fc5ed8b07c4b 444 SMART SM00912 47 147 3.7E-17 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal MC49_RS16160 55ad971bbb804d2ee1d9fc5ed8b07c4b 444 Pfam PF05860 haemagglutination activity domain 34 144 7.3E-25 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal MC49_RS16160 55ad971bbb804d2ee1d9fc5ed8b07c4b 444 SUPERFAMILY SSF51126 48 305 8.47E-25 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor MC49_RS00450 67ca3e52119fb61a47f2f7ceb16effdb 462 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 15 313 1.2E-141 T 29-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 MC49_RS00450 67ca3e52119fb61a47f2f7ceb16effdb 462 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 2 462 39.593 T 29-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 MC49_RS00450 67ca3e52119fb61a47f2f7ceb16effdb 462 Pfam PF09190 DALR domain 341 402 1.7E-25 T 29-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 MC49_RS00450 67ca3e52119fb61a47f2f7ceb16effdb 462 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 2 461 3.6E-193 T 29-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 MC49_RS00450 67ca3e52119fb61a47f2f7ceb16effdb 462 Gene3D G3DSA:3.40.50.620 1 305 2.0E-95 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS00450 67ca3e52119fb61a47f2f7ceb16effdb 462 Gene3D G3DSA:1.20.120.640 306 392 3.9E-22 T 29-03-2018 MC49_RS00450 67ca3e52119fb61a47f2f7ceb16effdb 462 SUPERFAMILY SSF47323 316 461 5.75E-43 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS00450 67ca3e52119fb61a47f2f7ceb16effdb 462 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 1.8E-30 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MC49_RS00450 67ca3e52119fb61a47f2f7ceb16effdb 462 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 1.8E-30 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MC49_RS00450 67ca3e52119fb61a47f2f7ceb16effdb 462 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 61 70 1.8E-30 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MC49_RS00450 67ca3e52119fb61a47f2f7ceb16effdb 462 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 25 36 1.8E-30 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MC49_RS00450 67ca3e52119fb61a47f2f7ceb16effdb 462 SUPERFAMILY SSF52374 1 313 8.04E-104 T 29-03-2018 MC49_RS00450 67ca3e52119fb61a47f2f7ceb16effdb 462 SMART SM00840 341 402 4.4E-30 T 29-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 MC49_RS00865 61fac0d96dab648fc4865c40a822be10 369 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 8 362 8.3E-135 T 29-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 MC49_RS00865 61fac0d96dab648fc4865c40a822be10 369 Pfam PF01872 RibD C-terminal domain 148 361 2.2E-50 T 29-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 MC49_RS00865 61fac0d96dab648fc4865c40a822be10 369 SUPERFAMILY SSF53597 145 363 7.51E-53 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 MC49_RS00865 61fac0d96dab648fc4865c40a822be10 369 PIRSF PIRSF006769 1 368 3.9E-126 T 29-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 MC49_RS00865 61fac0d96dab648fc4865c40a822be10 369 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 147 364 4.4E-61 T 29-03-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 MC49_RS00865 61fac0d96dab648fc4865c40a822be10 369 Gene3D G3DSA:3.40.140.10 1 125 3.8E-36 T 29-03-2018 MC49_RS00865 61fac0d96dab648fc4865c40a822be10 369 SUPERFAMILY SSF53927 4 146 4.68E-51 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 MC49_RS00865 61fac0d96dab648fc4865c40a822be10 369 Gene3D G3DSA:3.40.430.10 126 365 2.8E-63 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 MC49_RS00865 61fac0d96dab648fc4865c40a822be10 369 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 1 100 7.7E-22 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain MC49_RS00865 61fac0d96dab648fc4865c40a822be10 369 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 51 89 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 MC49_RS05305 00edf81a920d11940ce45dca60b8b5ff 309 SUPERFAMILY SSF56601 4 308 8.74E-104 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MC49_RS05305 00edf81a920d11940ce45dca60b8b5ff 309 Gene3D G3DSA:3.40.710.10 1 309 2.9E-105 T 29-03-2018 MC49_RS05305 00edf81a920d11940ce45dca60b8b5ff 309 Pfam PF04960 Glutaminase 24 308 5.5E-99 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 MC49_RS05305 00edf81a920d11940ce45dca60b8b5ff 309 Hamap MF_00313 Glutaminase [glsA]. 6 308 40.708 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 MC49_RS05305 00edf81a920d11940ce45dca60b8b5ff 309 TIGRFAM TIGR03814 Gln_ase: glutaminase A 17 308 4.3E-107 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 MC49_RS17425 bfb5a9d54db65e8dee0f4670aaec3149 464 Gene3D G3DSA:3.40.50.280 54 148 8.6E-10 T 29-03-2018 MC49_RS17425 bfb5a9d54db65e8dee0f4670aaec3149 464 Pfam PF13282 Domain of unknown function (DUF4070) 362 427 5.9E-5 T 29-03-2018 IPR025274 Domain of unknown function DUF4070 MC49_RS17425 bfb5a9d54db65e8dee0f4670aaec3149 464 SMART SM00729 176 386 1.3E-16 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MC49_RS17425 bfb5a9d54db65e8dee0f4670aaec3149 464 SUPERFAMILY SSF102114 177 378 1.05E-31 T 29-03-2018 MC49_RS17425 bfb5a9d54db65e8dee0f4670aaec3149 464 Pfam PF04055 Radical SAM superfamily 181 341 6.1E-11 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MC49_RS17425 bfb5a9d54db65e8dee0f4670aaec3149 464 Gene3D G3DSA:3.20.20.70 149 424 2.9E-28 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS17425 bfb5a9d54db65e8dee0f4670aaec3149 464 Pfam PF02310 B12 binding domain 59 135 2.5E-11 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 MC49_RS12420 69c15761a840f66a4575693499e9c7b9 193 SUPERFAMILY SSF160930 5 161 3.66E-62 T 29-03-2018 MC49_RS12420 69c15761a840f66a4575693499e9c7b9 193 PIRSF PIRSF003159 1 181 7.3E-88 T 29-03-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 MC49_RS12420 69c15761a840f66a4575693499e9c7b9 193 Pfam PF05280 Flagellar transcriptional activator (FlhC) 1 173 1.7E-82 T 29-03-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 MC49_RS12420 69c15761a840f66a4575693499e9c7b9 193 ProDom PD016592 ACTIVATOR TRANSCRIPTIONAL FLAGELLUM FLAGELLAR TRANSCRIPTION FLHC RNA DNA-BINDING REGULATION DNA-DIRECTED 1 181 1.0E-80 T 29-03-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 MC49_RS12420 69c15761a840f66a4575693499e9c7b9 193 Hamap MF_01891 Flagellar transcriptional regulator FlhC [flhC]. 1 187 45.215 T 29-03-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 MC49_RS12190 214f21d29598f8bf4271df79e56e90c4 374 Gene3D G3DSA:3.20.20.120 20 188 8.7E-20 T 29-03-2018 IPR029065 Enolase C-terminal domain-like MC49_RS12190 214f21d29598f8bf4271df79e56e90c4 374 Pfam PF04551 GcpE protein 14 354 3.8E-131 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 MC49_RS12190 214f21d29598f8bf4271df79e56e90c4 374 SUPERFAMILY SSF51604 23 139 3.14E-10 T 29-03-2018 IPR029065 Enolase C-terminal domain-like MC49_RS12190 214f21d29598f8bf4271df79e56e90c4 374 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 9 352 8.6E-126 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 MC49_RS12190 214f21d29598f8bf4271df79e56e90c4 374 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 7 359 34.919 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 MC49_RS12190 214f21d29598f8bf4271df79e56e90c4 374 SUPERFAMILY SSF56014 265 353 6.32E-10 T 29-03-2018 MC49_RS12190 214f21d29598f8bf4271df79e56e90c4 374 PIRSF PIRSF004640 1 364 2.0E-146 T 29-03-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 MC49_RS00925 476779b47268c72748073f2995d3edb5 430 Pfam PF00149 Calcineurin-like phosphoesterase 1 95 2.8E-12 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MC49_RS00925 476779b47268c72748073f2995d3edb5 430 Gene3D G3DSA:3.60.21.10 67 280 8.0E-25 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like MC49_RS00925 476779b47268c72748073f2995d3edb5 430 Gene3D G3DSA:3.60.21.10 1 66 7.7E-15 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like MC49_RS00925 476779b47268c72748073f2995d3edb5 430 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 257 4.8E-74 T 29-03-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 MC49_RS00925 476779b47268c72748073f2995d3edb5 430 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 279 377 3.9E-24 T 29-03-2018 IPR026843 Nuclease SbcCD subunit D, C-terminal domain MC49_RS00925 476779b47268c72748073f2995d3edb5 430 SUPERFAMILY SSF56300 1 340 1.97E-58 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like MC49_RS02765 c68a68896eafc4098022a8c20ddc5b7e 210 SUPERFAMILY SSF46689 161 203 5.82E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS02765 c68a68896eafc4098022a8c20ddc5b7e 210 SMART SM00342 119 202 6.6E-8 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MC49_RS02765 c68a68896eafc4098022a8c20ddc5b7e 210 Pfam PF12833 Helix-turn-helix domain 126 203 1.3E-10 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MC49_RS02765 c68a68896eafc4098022a8c20ddc5b7e 210 Gene3D G3DSA:1.10.10.60 100 151 0.0049 T 29-03-2018 MC49_RS02765 c68a68896eafc4098022a8c20ddc5b7e 210 Gene3D G3DSA:1.10.10.60 152 207 8.2E-7 T 29-03-2018 MC49_RS06060 07bcfd32daf2a569643b7d02b589221d 701 Gene3D G3DSA:3.10.20.30 382 457 8.9E-23 T 29-03-2018 IPR012675 Beta-grasp domain MC49_RS06060 07bcfd32daf2a569643b7d02b589221d 701 SUPERFAMILY SSF81301 180 392 1.63E-63 T 29-03-2018 MC49_RS06060 07bcfd32daf2a569643b7d02b589221d 701 SMART SM00954 235 345 6.0E-64 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 MC49_RS06060 07bcfd32daf2a569643b7d02b589221d 701 SUPERFAMILY SSF109604 3 190 3.45E-76 T 29-03-2018 MC49_RS06060 07bcfd32daf2a569643b7d02b589221d 701 Pfam PF13291 ACT domain 622 698 1.4E-13 T 29-03-2018 IPR002912 ACT domain MC49_RS06060 07bcfd32daf2a569643b7d02b589221d 701 Pfam PF04607 Region found in RelA / SpoT proteins 235 345 2.2E-36 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 MC49_RS06060 07bcfd32daf2a569643b7d02b589221d 701 Gene3D G3DSA:3.30.70.260 622 700 5.9E-9 T 29-03-2018 MC49_RS06060 07bcfd32daf2a569643b7d02b589221d 701 Gene3D G3DSA:3.30.460.10 192 325 9.4E-42 T 29-03-2018 MC49_RS06060 07bcfd32daf2a569643b7d02b589221d 701 SUPERFAMILY SSF81271 375 447 1.59E-21 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 MC49_RS06060 07bcfd32daf2a569643b7d02b589221d 701 SMART SM00471 41 153 2.3E-12 T 29-03-2018 IPR003607 HD/PDEase domain MC49_RS06060 07bcfd32daf2a569643b7d02b589221d 701 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 26 697 1.5E-281 T 29-03-2018 IPR004811 RelA/SpoT family GO:0015969 MC49_RS06060 07bcfd32daf2a569643b7d02b589221d 701 Pfam PF02824 TGS domain 388 447 4.6E-21 T 29-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 MC49_RS06060 07bcfd32daf2a569643b7d02b589221d 701 Pfam PF13328 HD domain 26 175 2.4E-52 T 29-03-2018 IPR003607 HD/PDEase domain MC49_RS06060 07bcfd32daf2a569643b7d02b589221d 701 SUPERFAMILY SSF55021 628 698 2.83E-5 T 29-03-2018 MC49_RS15340 35ad5e16e164f629fcae3fee888ee476 200 Hamap MF_00124 Thymidine kinase [tdk]. 1 189 34.464 T 29-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 MC49_RS15340 35ad5e16e164f629fcae3fee888ee476 200 Gene3D G3DSA:3.30.60.20 142 193 2.0E-15 T 29-03-2018 MC49_RS15340 35ad5e16e164f629fcae3fee888ee476 200 Gene3D G3DSA:3.40.50.300 2 141 2.4E-45 T 29-03-2018 MC49_RS15340 35ad5e16e164f629fcae3fee888ee476 200 PIRSF PIRSF035805 1 199 5.0E-58 T 29-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 MC49_RS15340 35ad5e16e164f629fcae3fee888ee476 200 SUPERFAMILY SSF57716 142 193 1.24E-15 T 29-03-2018 MC49_RS15340 35ad5e16e164f629fcae3fee888ee476 200 Pfam PF00265 Thymidine kinase 2 186 1.9E-61 T 29-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 MC49_RS15340 35ad5e16e164f629fcae3fee888ee476 200 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 173 186 - T 29-03-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 MC49_RS15340 35ad5e16e164f629fcae3fee888ee476 200 SUPERFAMILY SSF52540 2 141 1.02E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS18840 7efe8c72097292392568198010c1943f 307 SUPERFAMILY SSF52768 16 303 1.55E-90 T 29-03-2018 MC49_RS18840 7efe8c72097292392568198010c1943f 307 Hamap MF_01418 Agmatinase [speB]. 3 306 66.413 T 29-03-2018 IPR023694 Agmatinase GO:0008783|GO:0009446|GO:0030145 KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305 MC49_RS18840 7efe8c72097292392568198010c1943f 307 ProSitePatterns PS01053 Arginase family signature. 230 251 - T 29-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 MC49_RS18840 7efe8c72097292392568198010c1943f 307 Pfam PF00491 Arginase family 36 299 1.1E-85 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 MC49_RS18840 7efe8c72097292392568198010c1943f 307 TIGRFAM TIGR01230 agmatinase: agmatinase 24 300 3.1E-107 T 29-03-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 MC49_RS18840 7efe8c72097292392568198010c1943f 307 Gene3D G3DSA:3.40.800.10 3 307 1.9E-93 T 29-03-2018 MC49_RS18840 7efe8c72097292392568198010c1943f 307 PIRSF PIRSF036979 15 306 3.0E-98 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 MC49_RS05480 62263a752a379d9d504762e47ce03dc3 302 Pfam PF03466 LysR substrate binding domain 91 295 2.5E-29 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS05480 62263a752a379d9d504762e47ce03dc3 302 Gene3D G3DSA:3.40.190.10 89 175 3.4E-8 T 29-03-2018 MC49_RS05480 62263a752a379d9d504762e47ce03dc3 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 5.2E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS05480 62263a752a379d9d504762e47ce03dc3 302 Gene3D G3DSA:3.40.190.10 176 262 8.1E-18 T 29-03-2018 MC49_RS05480 62263a752a379d9d504762e47ce03dc3 302 SUPERFAMILY SSF53850 90 298 2.53E-31 T 29-03-2018 MC49_RS05480 62263a752a379d9d504762e47ce03dc3 302 SUPERFAMILY SSF46785 2 85 6.52E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS05480 62263a752a379d9d504762e47ce03dc3 302 Gene3D G3DSA:1.10.10.10 1 88 1.6E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS13410 7e3df0ad57e3b7f6695c22eca16f2f68 114 Gene3D G3DSA:3.10.450.40 2 111 8.8E-4 T 29-03-2018 MC49_RS13885 9056257875661904bd1833b2b786f4c8 363 Pfam PF06071 Protein of unknown function (DUF933) 279 362 3.8E-39 T 29-03-2018 IPR013029 Domain of unknown function DUF933 Reactome: R-HSA-114608 MC49_RS13885 9056257875661904bd1833b2b786f4c8 363 SUPERFAMILY SSF81271 279 359 8.72E-36 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 MC49_RS13885 9056257875661904bd1833b2b786f4c8 363 Gene3D G3DSA:1.10.150.300 110 200 2.0E-28 T 29-03-2018 IPR023192 TGS-like domain Reactome: R-HSA-114608 MC49_RS13885 9056257875661904bd1833b2b786f4c8 363 PIRSF PIRSF006641 1 363 9.6E-158 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 MC49_RS13885 9056257875661904bd1833b2b786f4c8 363 Pfam PF01926 50S ribosome-binding GTPase 5 115 2.7E-21 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MC49_RS13885 9056257875661904bd1833b2b786f4c8 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 2.3E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MC49_RS13885 9056257875661904bd1833b2b786f4c8 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 2.3E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MC49_RS13885 9056257875661904bd1833b2b786f4c8 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 2.3E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MC49_RS13885 9056257875661904bd1833b2b786f4c8 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 2.3E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MC49_RS13885 9056257875661904bd1833b2b786f4c8 363 Gene3D G3DSA:3.40.50.300 1 80 2.7E-8 T 29-03-2018 MC49_RS13885 9056257875661904bd1833b2b786f4c8 363 SUPERFAMILY SSF52540 3 301 1.27E-84 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS13885 9056257875661904bd1833b2b786f4c8 363 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 363 8.9E-175 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 MC49_RS13885 9056257875661904bd1833b2b786f4c8 363 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 363 46.521 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 MC49_RS13885 9056257875661904bd1833b2b786f4c8 363 Gene3D G3DSA:3.10.20.30 263 362 3.4E-45 T 29-03-2018 IPR012675 Beta-grasp domain MC49_RS03900 3f661a59a614e78a51e333821a4fb63a 92 Gene3D G3DSA:3.30.70.260 2 92 1.6E-8 T 29-03-2018 MC49_RS03900 3f661a59a614e78a51e333821a4fb63a 92 Pfam PF13710 ACT domain 13 75 1.4E-21 T 29-03-2018 MC49_RS03900 3f661a59a614e78a51e333821a4fb63a 92 SUPERFAMILY SSF55021 2 78 5.0E-9 T 29-03-2018 MC49_RS07500 0a2015429ad3f1302bb9df86c10ea3ac 215 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 29-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 MC49_RS07500 0a2015429ad3f1302bb9df86c10ea3ac 215 PIRSF PIRSF000709 1 182 1.1E-11 T 29-03-2018 MC49_RS07500 0a2015429ad3f1302bb9df86c10ea3ac 215 SUPERFAMILY SSF53254 1 208 2.75E-57 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MC49_RS07500 0a2015429ad3f1302bb9df86c10ea3ac 215 SMART SM00855 3 157 1.2E-23 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MC49_RS07500 0a2015429ad3f1302bb9df86c10ea3ac 215 Gene3D G3DSA:3.40.50.1240 1 213 1.7E-56 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MC49_RS07500 0a2015429ad3f1302bb9df86c10ea3ac 215 Hamap MF_01040 Probable phosphoglycerate mutase GpmB [gpmB]. 1 215 49.836 T 29-03-2018 IPR023086 Phosphoglycerate mutase, GpmB, probable GO:0004619|GO:0006096 MC49_RS07500 0a2015429ad3f1302bb9df86c10ea3ac 215 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 194 1.1E-59 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MC49_RS05090 e870fd4485d74dbb3cff1c7e869812f9 501 Pfam PF00005 ABC transporter 22 169 1.7E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS05090 e870fd4485d74dbb3cff1c7e869812f9 501 Pfam PF00005 ABC transporter 269 423 4.9E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS05090 e870fd4485d74dbb3cff1c7e869812f9 501 SMART SM00382 277 472 4.2E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS05090 e870fd4485d74dbb3cff1c7e869812f9 501 SMART SM00382 29 226 5.1E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS05090 e870fd4485d74dbb3cff1c7e869812f9 501 ProSitePatterns PS00211 ABC transporters family signature. 396 410 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS05090 e870fd4485d74dbb3cff1c7e869812f9 501 Gene3D G3DSA:3.40.50.300 1 244 8.9E-53 T 29-03-2018 MC49_RS05090 e870fd4485d74dbb3cff1c7e869812f9 501 Gene3D G3DSA:3.40.50.300 245 491 6.8E-39 T 29-03-2018 MC49_RS05090 e870fd4485d74dbb3cff1c7e869812f9 501 SUPERFAMILY SSF52540 268 484 1.45E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS05090 e870fd4485d74dbb3cff1c7e869812f9 501 SUPERFAMILY SSF52540 2 231 1.25E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS18525 47e7ab3c5dc285966f758de0343d343a 865 SUPERFAMILY SSF74778 2 160 3.4E-66 T 29-03-2018 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 MC49_RS18525 47e7ab3c5dc285966f758de0343d343a 865 Pfam PF06434 Aconitate hydratase 2 N-terminus 168 382 1.3E-96 T 29-03-2018 IPR015929 Aconitase B, swivel GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 MC49_RS18525 47e7ab3c5dc285966f758de0343d343a 865 SUPERFAMILY SSF52016 162 371 1.96E-71 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel MC49_RS18525 47e7ab3c5dc285966f758de0343d343a 865 PIRSF PIRSF036687 1 859 0.0 T 29-03-2018 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 MC49_RS18525 47e7ab3c5dc285966f758de0343d343a 865 Gene3D G3DSA:3.30.499.10 683 865 2.0E-52 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS18525 47e7ab3c5dc285966f758de0343d343a 865 ProSitePatterns PS00450 Aconitase family signature 1. 702 719 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MC49_RS18525 47e7ab3c5dc285966f758de0343d343a 865 Gene3D G3DSA:3.30.499.10 402 520 2.6E-11 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS18525 47e7ab3c5dc285966f758de0343d343a 865 Pfam PF00330 Aconitase family (aconitate hydratase) 472 818 4.3E-40 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS18525 47e7ab3c5dc285966f758de0343d343a 865 Gene3D G3DSA:3.40.1060.10 521 682 1.3E-27 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS18525 47e7ab3c5dc285966f758de0343d343a 865 SUPERFAMILY SSF53732 379 857 9.55E-151 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS18525 47e7ab3c5dc285966f758de0343d343a 865 TIGRFAM TIGR00117 acnB: aconitate hydratase 2 1 853 0.0 T 29-03-2018 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 MC49_RS18525 47e7ab3c5dc285966f758de0343d343a 865 Pfam PF11791 Aconitate B N-terminal domain 4 156 2.4E-66 T 29-03-2018 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 MC49_RS18525 47e7ab3c5dc285966f758de0343d343a 865 ProSitePatterns PS01244 Aconitase family signature 2. 761 774 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MC49_RS18525 47e7ab3c5dc285966f758de0343d343a 865 Gene3D G3DSA:3.20.19.10 162 363 1.2E-33 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel MC49_RS03440 4ac5e29c031af2912d65be03e75203a0 389 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 4.9E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MC49_RS03440 4ac5e29c031af2912d65be03e75203a0 389 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 4.9E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MC49_RS03440 4ac5e29c031af2912d65be03e75203a0 389 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 4.9E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MC49_RS03440 4ac5e29c031af2912d65be03e75203a0 389 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 4.9E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MC49_RS03440 4ac5e29c031af2912d65be03e75203a0 389 Pfam PF01926 50S ribosome-binding GTPase 161 284 5.5E-24 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MC49_RS03440 4ac5e29c031af2912d65be03e75203a0 389 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 332 7.9E-149 T 29-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 MC49_RS03440 4ac5e29c031af2912d65be03e75203a0 389 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 29-03-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 MC49_RS03440 4ac5e29c031af2912d65be03e75203a0 389 Hamap MF_01454 GTPase Obg [obg]. 2 333 48.48 T 29-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 MC49_RS03440 4ac5e29c031af2912d65be03e75203a0 389 SUPERFAMILY SSF52540 151 334 5.01E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS03440 4ac5e29c031af2912d65be03e75203a0 389 Gene3D G3DSA:3.40.50.300 159 373 2.3E-30 T 29-03-2018 MC49_RS03440 4ac5e29c031af2912d65be03e75203a0 389 Gene3D G3DSA:2.70.210.12 2 156 8.5E-59 T 29-03-2018 IPR006169 GTP1/OBG domain MC49_RS03440 4ac5e29c031af2912d65be03e75203a0 389 Pfam PF01018 GTP1/OBG 4 157 1.9E-60 T 29-03-2018 IPR006169 GTP1/OBG domain MC49_RS03440 4ac5e29c031af2912d65be03e75203a0 389 SUPERFAMILY SSF82051 2 157 1.19E-58 T 29-03-2018 IPR006169 GTP1/OBG domain MC49_RS03440 4ac5e29c031af2912d65be03e75203a0 389 PIRSF PIRSF002401 1 376 1.5E-141 T 29-03-2018 IPR035101 GTP-binding protein, Obg-type MC49_RS09180 3d86b361c376e14e118d5e61acd23c7a 744 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 64 741 7.1E-187 T 29-03-2018 IPR004811 RelA/SpoT family GO:0015969 MC49_RS09180 3d86b361c376e14e118d5e61acd23c7a 744 Gene3D G3DSA:3.30.70.260 664 743 1.7E-11 T 29-03-2018 MC49_RS09180 3d86b361c376e14e118d5e61acd23c7a 744 SUPERFAMILY SSF55021 666 743 1.45E-13 T 29-03-2018 MC49_RS09180 3d86b361c376e14e118d5e61acd23c7a 744 Pfam PF13328 HD domain 51 191 1.6E-38 T 29-03-2018 IPR003607 HD/PDEase domain MC49_RS09180 3d86b361c376e14e118d5e61acd23c7a 744 Pfam PF04607 Region found in RelA / SpoT proteins 251 360 2.3E-36 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 MC49_RS09180 3d86b361c376e14e118d5e61acd23c7a 744 SUPERFAMILY SSF81271 399 465 1.19E-21 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 MC49_RS09180 3d86b361c376e14e118d5e61acd23c7a 744 SUPERFAMILY SSF81301 196 410 3.6E-65 T 29-03-2018 MC49_RS09180 3d86b361c376e14e118d5e61acd23c7a 744 Gene3D G3DSA:3.10.20.30 400 475 2.3E-24 T 29-03-2018 IPR012675 Beta-grasp domain MC49_RS09180 3d86b361c376e14e118d5e61acd23c7a 744 SUPERFAMILY SSF109604 20 207 2.54E-45 T 29-03-2018 MC49_RS09180 3d86b361c376e14e118d5e61acd23c7a 744 Pfam PF02824 TGS domain 406 465 1.2E-20 T 29-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 MC49_RS09180 3d86b361c376e14e118d5e61acd23c7a 744 SMART SM00954 251 361 1.9E-66 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 MC49_RS09180 3d86b361c376e14e118d5e61acd23c7a 744 Pfam PF13291 ACT domain 665 741 1.6E-18 T 29-03-2018 IPR002912 ACT domain MC49_RS09180 3d86b361c376e14e118d5e61acd23c7a 744 Gene3D G3DSA:3.30.460.10 208 341 1.1E-43 T 29-03-2018 MC49_RS10070 890b647e4f465e3e9286d180e5c41e01 69 Pfam PF00313 'Cold-shock' DNA-binding domain 5 68 1.4E-32 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MC49_RS10070 890b647e4f465e3e9286d180e5c41e01 69 SMART SM00357 5 69 4.4E-31 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 MC49_RS10070 890b647e4f465e3e9286d180e5c41e01 69 ProSitePatterns PS00352 'Cold-shock' domain signature. 17 36 - T 29-03-2018 IPR019844 Cold-shock conserved site MC49_RS10070 890b647e4f465e3e9286d180e5c41e01 69 PRINTS PR00050 Cold shock protein signature 42 60 5.7E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MC49_RS10070 890b647e4f465e3e9286d180e5c41e01 69 PRINTS PR00050 Cold shock protein signature 27 36 5.7E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MC49_RS10070 890b647e4f465e3e9286d180e5c41e01 69 PRINTS PR00050 Cold shock protein signature 6 21 5.7E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MC49_RS10070 890b647e4f465e3e9286d180e5c41e01 69 Gene3D G3DSA:2.40.50.140 3 69 5.1E-28 T 29-03-2018 MC49_RS10070 890b647e4f465e3e9286d180e5c41e01 69 SUPERFAMILY SSF50249 4 68 5.31E-26 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS10070 890b647e4f465e3e9286d180e5c41e01 69 PIRSF PIRSF002599 1 69 2.1E-25 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 MC49_RS01120 51514717127168abaaa8c215cd8e67ff 1038 Gene3D G3DSA:3.30.2090.10 714 801 1.7E-15 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MC49_RS01120 51514717127168abaaa8c215cd8e67ff 1038 Pfam PF00873 AcrB/AcrD/AcrF family 5 1015 3.6E-165 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS01120 51514717127168abaaa8c215cd8e67ff 1038 Gene3D G3DSA:3.30.70.1430 560 664 5.7E-4 T 29-03-2018 MC49_RS01120 51514717127168abaaa8c215cd8e67ff 1038 Gene3D G3DSA:3.30.70.1430 40 142 3.8E-24 T 29-03-2018 MC49_RS01120 51514717127168abaaa8c215cd8e67ff 1038 Gene3D G3DSA:1.20.1640.10 802 1018 1.0E-39 T 29-03-2018 MC49_RS01120 51514717127168abaaa8c215cd8e67ff 1038 Gene3D G3DSA:1.20.1640.10 277 498 5.5E-37 T 29-03-2018 MC49_RS01120 51514717127168abaaa8c215cd8e67ff 1038 SUPERFAMILY SSF82714 183 250 4.71E-7 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MC49_RS01120 51514717127168abaaa8c215cd8e67ff 1038 SUPERFAMILY SSF82693 41 132 4.71E-16 T 29-03-2018 MC49_RS01120 51514717127168abaaa8c215cd8e67ff 1038 SUPERFAMILY SSF82714 716 801 3.27E-13 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MC49_RS01120 51514717127168abaaa8c215cd8e67ff 1038 SUPERFAMILY SSF82866 299 497 1.03E-39 T 29-03-2018 MC49_RS01120 51514717127168abaaa8c215cd8e67ff 1038 SUPERFAMILY SSF82693 136 180 1.22E-15 T 29-03-2018 MC49_RS01120 51514717127168abaaa8c215cd8e67ff 1038 SUPERFAMILY SSF82693 276 328 1.22E-15 T 29-03-2018 MC49_RS01120 51514717127168abaaa8c215cd8e67ff 1038 Gene3D G3DSA:3.30.2090.10 179 275 1.6E-9 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MC49_RS01120 51514717127168abaaa8c215cd8e67ff 1038 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.2E-25 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS01120 51514717127168abaaa8c215cd8e67ff 1038 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 1.2E-25 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS01120 51514717127168abaaa8c215cd8e67ff 1038 PRINTS PR00702 Acriflavin resistance protein family signature 364 385 1.2E-25 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS01120 51514717127168abaaa8c215cd8e67ff 1038 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.2E-25 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS01120 51514717127168abaaa8c215cd8e67ff 1038 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 1.2E-25 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS01120 51514717127168abaaa8c215cd8e67ff 1038 PRINTS PR00702 Acriflavin resistance protein family signature 392 416 1.2E-25 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS01120 51514717127168abaaa8c215cd8e67ff 1038 PRINTS PR00702 Acriflavin resistance protein family signature 545 562 1.2E-25 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 MC49_RS01120 51514717127168abaaa8c215cd8e67ff 1038 SUPERFAMILY SSF82866 801 1022 1.19E-46 T 29-03-2018 MC49_RS08740 3c2b2ff4d5cb29e52e493f579202d53a 369 SUPERFAMILY SSF50129 318 369 1.25E-11 T 29-03-2018 IPR011032 GroES-like MC49_RS08740 3c2b2ff4d5cb29e52e493f579202d53a 369 SMART SM00829 12 367 3.8E-4 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MC49_RS08740 3c2b2ff4d5cb29e52e493f579202d53a 369 Pfam PF00107 Zinc-binding dehydrogenase 197 329 2.9E-22 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MC49_RS08740 3c2b2ff4d5cb29e52e493f579202d53a 369 Gene3D G3DSA:3.90.180.10 1 188 6.8E-59 T 29-03-2018 MC49_RS08740 3c2b2ff4d5cb29e52e493f579202d53a 369 TIGRFAM TIGR02818 adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 2 369 4.9E-221 T 29-03-2018 IPR014183 Alcohol dehydrogenase class III GO:0006069|GO:0008270|GO:0051903|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00620+1.1.1.28|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00680+1.1.1.284|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-1801|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6454|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-6901|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396|MetaCyc: PWY-7798|Reactome: R-HSA-71384 MC49_RS08740 3c2b2ff4d5cb29e52e493f579202d53a 369 Gene3D G3DSA:3.40.50.720 189 309 4.5E-23 T 29-03-2018 MC49_RS08740 3c2b2ff4d5cb29e52e493f579202d53a 369 SUPERFAMILY SSF51735 161 334 1.62E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS08740 3c2b2ff4d5cb29e52e493f579202d53a 369 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MC49_RS08740 3c2b2ff4d5cb29e52e493f579202d53a 369 SUPERFAMILY SSF50129 1 184 2.43E-70 T 29-03-2018 IPR011032 GroES-like MC49_RS08740 3c2b2ff4d5cb29e52e493f579202d53a 369 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 154 3.6E-26 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MC49_RS08740 3c2b2ff4d5cb29e52e493f579202d53a 369 Gene3D G3DSA:3.90.180.10 310 369 7.4E-6 T 29-03-2018 MC49_RS06415 b0834648bdb6f3239aeac5c2ea93c1cd 165 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 78 155 0.001 T 29-03-2018 MC49_RS06415 b0834648bdb6f3239aeac5c2ea93c1cd 165 Pfam PF00466 Ribosomal protein L10 5 101 4.6E-26 T 29-03-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 MC49_RS06415 b0834648bdb6f3239aeac5c2ea93c1cd 165 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 162 26.741 T 29-03-2018 IPR022973 Ribosomal protein L10 MC49_RS06415 b0834648bdb6f3239aeac5c2ea93c1cd 165 SUPERFAMILY SSF160369 4 162 5.62E-49 T 29-03-2018 MC49_RS06415 b0834648bdb6f3239aeac5c2ea93c1cd 165 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 29-03-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS06525 443371e3054b76dd25902ccfc8bdc757 355 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 9 346 2.3E-136 T 29-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MC49_RS06525 443371e3054b76dd25902ccfc8bdc757 355 Gene3D G3DSA:3.20.20.210 1 355 9.7E-113 T 29-03-2018 MC49_RS06525 443371e3054b76dd25902ccfc8bdc757 355 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 142 158 - T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MC49_RS06525 443371e3054b76dd25902ccfc8bdc757 355 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 6 349 50.666 T 29-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MC49_RS06525 443371e3054b76dd25902ccfc8bdc757 355 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 5 347 2.5E-143 T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MC49_RS06525 443371e3054b76dd25902ccfc8bdc757 355 SUPERFAMILY SSF51726 2 353 3.49E-124 T 29-03-2018 MC49_RS06525 443371e3054b76dd25902ccfc8bdc757 355 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 22 31 - T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MC49_RS18000 844e7e25814e426c81b37113cf35e2f0 673 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 410 436 7.6E-10 T 29-03-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 MC49_RS18000 844e7e25814e426c81b37113cf35e2f0 673 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 117 146 - T 29-03-2018 IPR018239 NAD-dependent DNA ligase, active site MC49_RS18000 844e7e25814e426c81b37113cf35e2f0 673 PIRSF PIRSF001604 1 673 3.3E-252 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 MC49_RS18000 844e7e25814e426c81b37113cf35e2f0 673 Hamap MF_01588 DNA ligase [ligA]. 4 672 54.524 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 MC49_RS18000 844e7e25814e426c81b37113cf35e2f0 673 SUPERFAMILY SSF52113 598 672 1.44E-20 T 29-03-2018 IPR001357 BRCT domain MC49_RS18000 844e7e25814e426c81b37113cf35e2f0 673 SUPERFAMILY SSF56091 4 318 1.07E-122 T 29-03-2018 MC49_RS18000 844e7e25814e426c81b37113cf35e2f0 673 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 13 668 8.2E-268 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 MC49_RS18000 844e7e25814e426c81b37113cf35e2f0 673 SMART SM00292 598 673 1.1E-14 T 29-03-2018 IPR001357 BRCT domain MC49_RS18000 844e7e25814e426c81b37113cf35e2f0 673 SMART SM00532 5 450 3.5E-282 T 29-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 MC49_RS18000 844e7e25814e426c81b37113cf35e2f0 673 Gene3D G3DSA:3.40.50.10190 574 673 7.8E-26 T 29-03-2018 IPR001357 BRCT domain MC49_RS18000 844e7e25814e426c81b37113cf35e2f0 673 Pfam PF12826 Helix-hairpin-helix motif 512 575 2.8E-25 T 29-03-2018 MC49_RS18000 844e7e25814e426c81b37113cf35e2f0 673 Gene3D G3DSA:1.10.287.610 1 69 6.4E-27 T 29-03-2018 MC49_RS18000 844e7e25814e426c81b37113cf35e2f0 673 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 333 348 - T 29-03-2018 IPR033136 NAD-dependent DNA ligase, conserved site MC49_RS18000 844e7e25814e426c81b37113cf35e2f0 673 Pfam PF14520 Helix-hairpin-helix domain 448 502 3.5E-5 T 29-03-2018 MC49_RS18000 844e7e25814e426c81b37113cf35e2f0 673 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 599 672 1.2E-14 T 29-03-2018 IPR001357 BRCT domain MC49_RS18000 844e7e25814e426c81b37113cf35e2f0 673 SUPERFAMILY SSF50249 320 401 1.88E-28 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS18000 844e7e25814e426c81b37113cf35e2f0 673 SUPERFAMILY SSF47781 406 579 1.19E-59 T 29-03-2018 IPR010994 RuvA domain 2-like MC49_RS18000 844e7e25814e426c81b37113cf35e2f0 673 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 6 320 7.0E-138 T 29-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 MC49_RS18000 844e7e25814e426c81b37113cf35e2f0 673 Gene3D G3DSA:1.10.150.20 434 507 4.5E-24 T 29-03-2018 MC49_RS18000 844e7e25814e426c81b37113cf35e2f0 673 Gene3D G3DSA:3.30.470.30 121 239 3.6E-54 T 29-03-2018 MC49_RS18000 844e7e25814e426c81b37113cf35e2f0 673 Gene3D G3DSA:1.10.150.20 509 573 1.5E-26 T 29-03-2018 MC49_RS18000 844e7e25814e426c81b37113cf35e2f0 673 Gene3D G3DSA:2.40.50.140 324 392 3.6E-34 T 29-03-2018 MC49_RS18000 844e7e25814e426c81b37113cf35e2f0 673 SMART SM00278 514 533 150.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MC49_RS18000 844e7e25814e426c81b37113cf35e2f0 673 SMART SM00278 546 565 32.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MC49_RS18000 844e7e25814e426c81b37113cf35e2f0 673 SMART SM00278 482 501 3.6 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MC49_RS18000 844e7e25814e426c81b37113cf35e2f0 673 SMART SM00278 448 467 33.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MC49_RS18000 844e7e25814e426c81b37113cf35e2f0 673 Gene3D G3DSA:3.30.1490.70 240 323 2.2E-22 T 29-03-2018 MC49_RS18000 844e7e25814e426c81b37113cf35e2f0 673 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 324 400 1.5E-35 T 29-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 MC49_RS09615 861b7b550a1334a1e41c1208695b1ec2 232 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 1 227 2.0E-95 T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein MC49_RS09615 861b7b550a1334a1e41c1208695b1ec2 232 PIRSF PIRSF004848 1 232 4.2E-78 T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein MC49_RS09615 861b7b550a1334a1e41c1208695b1ec2 232 Pfam PF01168 Alanine racemase, N-terminal domain 7 227 6.4E-31 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MC49_RS09615 861b7b550a1334a1e41c1208695b1ec2 232 SUPERFAMILY SSF51419 2 225 4.06E-82 T 29-03-2018 IPR029066 PLP-binding barrel MC49_RS09615 861b7b550a1334a1e41c1208695b1ec2 232 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 77 91 - T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein MC49_RS09615 861b7b550a1334a1e41c1208695b1ec2 232 Gene3D G3DSA:3.20.20.10 1 232 1.4E-71 T 29-03-2018 IPR029066 PLP-binding barrel MC49_RS11320 4bb4b2cb058e228b0d9993f32611fee9 203 Gene3D G3DSA:3.30.1460.30 9 112 3.2E-13 T 29-03-2018 MC49_RS11320 4bb4b2cb058e228b0d9993f32611fee9 203 Pfam PF04994 TfoX C-terminal domain 122 198 1.4E-20 T 29-03-2018 IPR007077 TfoX, C-terminal MC49_RS11320 4bb4b2cb058e228b0d9993f32611fee9 203 Pfam PF04993 TfoX N-terminal domain 20 107 7.9E-21 T 29-03-2018 IPR007076 TfoX, N-terminal MC49_RS11320 4bb4b2cb058e228b0d9993f32611fee9 203 SUPERFAMILY SSF159894 16 110 2.09E-18 T 29-03-2018 MC49_RS11320 4bb4b2cb058e228b0d9993f32611fee9 203 Gene3D G3DSA:1.10.150.20 122 199 7.5E-15 T 29-03-2018 MC49_RS11320 4bb4b2cb058e228b0d9993f32611fee9 203 PIRSF PIRSF028788 5 203 3.8E-36 T 29-03-2018 IPR026256 Transcriptional regulator, TfoX/Sxy-type MC49_RS00880 a1788799bd0571724ff7e09ff0196664 615 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 345 594 4.9E-84 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MC49_RS00880 a1788799bd0571724ff7e09ff0196664 615 Pfam PF13721 SecD export protein N-terminal TM region 2 103 9.1E-37 T 29-03-2018 IPR027398 SecD export protein N-terminal TM domain MC49_RS00880 a1788799bd0571724ff7e09ff0196664 615 Pfam PF07549 SecD/SecF GG Motif 120 139 9.0E-6 T 29-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site MC49_RS00880 a1788799bd0571724ff7e09ff0196664 615 Gene3D G3DSA:1.20.1640.10 388 607 2.0E-31 T 29-03-2018 MC49_RS00880 a1788799bd0571724ff7e09ff0196664 615 SUPERFAMILY SSF82866 334 349 7.32E-42 T 29-03-2018 MC49_RS00880 a1788799bd0571724ff7e09ff0196664 615 SUPERFAMILY SSF82866 410 606 7.32E-42 T 29-03-2018 MC49_RS00880 a1788799bd0571724ff7e09ff0196664 615 Pfam PF02355 Protein export membrane protein 433 601 1.3E-16 T 29-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial MC49_RS00880 a1788799bd0571724ff7e09ff0196664 615 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 3 615 49.489 T 29-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 MC49_RS00880 a1788799bd0571724ff7e09ff0196664 615 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 123 601 6.2E-149 T 29-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 MC49_RS06490 8bb9b11a5e0a80ffd64c16cc8bcf7e65 224 Pfam PF12710 haloacid dehalogenase-like hydrolase 5 189 3.8E-32 T 29-03-2018 MC49_RS06490 8bb9b11a5e0a80ffd64c16cc8bcf7e65 224 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 4 189 9.3E-29 T 29-03-2018 MC49_RS06490 8bb9b11a5e0a80ffd64c16cc8bcf7e65 224 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 4 201 8.7E-43 T 29-03-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like MC49_RS06490 8bb9b11a5e0a80ffd64c16cc8bcf7e65 224 SUPERFAMILY SSF56784 3 211 9.67E-30 T 29-03-2018 IPR023214 HAD-like domain MC49_RS06490 8bb9b11a5e0a80ffd64c16cc8bcf7e65 224 Gene3D G3DSA:3.40.50.1000 78 209 2.3E-14 T 29-03-2018 IPR023214 HAD-like domain MC49_RS06490 8bb9b11a5e0a80ffd64c16cc8bcf7e65 224 Gene3D G3DSA:1.20.1440.100 17 77 3.5E-24 T 29-03-2018 MC49_RS02585 4acbf630cc11492a10789b9a0f174e9d 349 Pfam PF03747 ADP-ribosylglycohydrolase 18 311 4.6E-55 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 MC49_RS02585 4acbf630cc11492a10789b9a0f174e9d 349 Gene3D G3DSA:1.10.4080.10 6 340 1.7E-62 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 MC49_RS02585 4acbf630cc11492a10789b9a0f174e9d 349 SUPERFAMILY SSF101478 14 337 3.79E-62 T 29-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 MC49_RS01690 bdd0b8069f9bd2f69f8a5608a65d04e3 153 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 109 126 - T 29-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MC49_RS01690 bdd0b8069f9bd2f69f8a5608a65d04e3 153 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 99 113 3.1E-18 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 MC49_RS01690 bdd0b8069f9bd2f69f8a5608a65d04e3 153 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 82 95 3.1E-18 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 MC49_RS01690 bdd0b8069f9bd2f69f8a5608a65d04e3 153 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 114 127 3.1E-18 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 MC49_RS01690 bdd0b8069f9bd2f69f8a5608a65d04e3 153 Gene3D G3DSA:2.40.50.100 4 153 3.0E-19 T 29-03-2018 MC49_RS01690 bdd0b8069f9bd2f69f8a5608a65d04e3 153 Pfam PF00364 Biotin-requiring enzyme 79 152 2.0E-24 T 29-03-2018 IPR000089 Biotin/lipoyl attachment MC49_RS01690 bdd0b8069f9bd2f69f8a5608a65d04e3 153 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 153 2.2E-62 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 MC49_RS01690 bdd0b8069f9bd2f69f8a5608a65d04e3 153 SUPERFAMILY SSF51230 78 153 5.1E-25 T 29-03-2018 IPR011053 Single hybrid motif MC49_RS15395 611006f15564a2ecf24349a89b19cbb3 654 Gene3D G3DSA:3.40.50.140 1 156 6.6E-37 T 29-03-2018 MC49_RS15395 611006f15564a2ecf24349a89b19cbb3 654 SUPERFAMILY SSF56712 1 608 3.92E-184 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain MC49_RS15395 611006f15564a2ecf24349a89b19cbb3 654 Gene3D G3DSA:2.70.20.10 363 480 2.1E-25 T 29-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 MC49_RS15395 611006f15564a2ecf24349a89b19cbb3 654 SMART SM00493 1 124 1.4E-24 T 29-03-2018 IPR006171 TOPRIM domain MC49_RS15395 611006f15564a2ecf24349a89b19cbb3 654 Pfam PF01751 Toprim domain 3 135 2.4E-14 T 29-03-2018 IPR006171 TOPRIM domain MC49_RS15395 611006f15564a2ecf24349a89b19cbb3 654 Pfam PF01131 DNA topoisomerase 158 592 2.8E-111 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MC49_RS15395 611006f15564a2ecf24349a89b19cbb3 654 TIGRFAM TIGR01056 topB: DNA topoisomerase III 1 633 5.6E-272 T 29-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 MC49_RS15395 611006f15564a2ecf24349a89b19cbb3 654 Hamap MF_00953 DNA topoisomerase 3 [topB]. 1 654 64.997 T 29-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 MC49_RS15395 611006f15564a2ecf24349a89b19cbb3 654 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 323 332 4.2E-27 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MC49_RS15395 611006f15564a2ecf24349a89b19cbb3 654 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 402 418 4.2E-27 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MC49_RS15395 611006f15564a2ecf24349a89b19cbb3 654 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 193 211 4.2E-27 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MC49_RS15395 611006f15564a2ecf24349a89b19cbb3 654 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 521 535 4.2E-27 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MC49_RS15395 611006f15564a2ecf24349a89b19cbb3 654 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 98 111 4.2E-27 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MC49_RS15395 611006f15564a2ecf24349a89b19cbb3 654 SMART SM00436 128 223 1.0E-33 T 29-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 MC49_RS15395 611006f15564a2ecf24349a89b19cbb3 654 SMART SM00437 280 558 4.8E-103 T 29-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 MC49_RS15395 611006f15564a2ecf24349a89b19cbb3 654 Gene3D G3DSA:1.10.460.10 157 357 2.4E-39 T 29-03-2018 MC49_RS15395 611006f15564a2ecf24349a89b19cbb3 654 Gene3D G3DSA:1.10.460.10 481 614 7.4E-17 T 29-03-2018 MC49_RS15395 611006f15564a2ecf24349a89b19cbb3 654 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 317 332 - T 29-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 MC49_RS02410 27a28d6302bfac8078294e401f837ebb 186 Gene3D G3DSA:1.10.443.10 6 184 5.8E-35 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MC49_RS02410 27a28d6302bfac8078294e401f837ebb 186 SUPERFAMILY SSF56349 3 184 2.21E-41 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MC49_RS02410 27a28d6302bfac8078294e401f837ebb 186 Pfam PF00589 Phage integrase family 9 177 6.1E-41 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MC49_RS03070 2d7d0f35b3d55401a1066fd33f5d1702 360 Pfam PF01497 Periplasmic binding protein 91 306 3.2E-19 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 MC49_RS03070 2d7d0f35b3d55401a1066fd33f5d1702 360 Gene3D G3DSA:3.40.50.1980 7 151 2.9E-14 T 29-03-2018 MC49_RS03070 2d7d0f35b3d55401a1066fd33f5d1702 360 SUPERFAMILY SSF53807 18 350 7.46E-39 T 29-03-2018 MC49_RS03070 2d7d0f35b3d55401a1066fd33f5d1702 360 Gene3D G3DSA:3.40.50.1980 152 336 5.8E-36 T 29-03-2018 MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SUPERFAMILY SSF49373 2997 3084 1.02E-12 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SUPERFAMILY SSF49373 966 1058 4.12E-16 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SUPERFAMILY SSF49373 1164 1259 5.49E-20 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SUPERFAMILY SSF49373 560 660 1.12E-7 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Gene3D G3DSA:2.60.120.260 1108 1211 1.5E-23 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Gene3D G3DSA:2.60.120.260 809 912 3.6E-13 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Gene3D G3DSA:2.60.120.260 2536 2638 6.9E-25 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Gene3D G3DSA:2.60.120.260 2333 2434 2.0E-24 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Gene3D G3DSA:2.60.120.260 2843 2944 4.7E-25 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Gene3D G3DSA:2.60.120.260 1823 1924 6.1E-25 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Gene3D G3DSA:2.60.120.260 1517 1616 6.1E-25 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Gene3D G3DSA:2.60.120.260 709 808 2.7E-13 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Gene3D G3DSA:2.60.120.260 1414 1516 4.8E-25 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Gene3D G3DSA:2.60.120.260 2435 2535 4.7E-22 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Gene3D G3DSA:2.60.120.260 1617 1721 3.5E-26 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Gene3D G3DSA:2.60.120.260 2029 2130 4.8E-23 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Gene3D G3DSA:2.60.120.260 2131 2232 4.7E-24 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Gene3D G3DSA:2.60.120.260 1722 1822 5.7E-25 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Gene3D G3DSA:2.60.120.260 2743 2842 9.9E-23 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Gene3D G3DSA:2.60.120.260 600 708 5.6E-11 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Gene3D G3DSA:2.60.120.260 1013 1107 3.6E-21 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Gene3D G3DSA:2.60.120.260 1313 1413 3.9E-26 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Gene3D G3DSA:2.60.120.260 2639 2742 3.3E-24 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Gene3D G3DSA:2.60.120.260 436 599 2.3E-9 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Gene3D G3DSA:2.60.120.260 913 1012 2.8E-16 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Gene3D G3DSA:2.60.120.260 1212 1312 2.7E-21 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Gene3D G3DSA:2.60.120.260 2945 3039 4.1E-19 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Gene3D G3DSA:2.60.120.260 2233 2332 1.1E-23 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Gene3D G3DSA:2.60.120.260 1925 2028 2.2E-24 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SUPERFAMILY SSF49373 868 958 7.06E-19 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SUPERFAMILY SSF49373 1775 1870 2.62E-19 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SUPERFAMILY SSF49373 2796 2891 5.49E-20 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SUPERFAMILY SSF49373 2286 2381 1.45E-18 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Pfam PF13620 Carboxypeptidase regulatory-like domain 3117 3187 1.5E-7 T 29-03-2018 MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SUPERFAMILY SSF49373 1060 1155 1.45E-19 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SUPERFAMILY SSF49373 2592 2687 1.75E-19 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SUPERFAMILY SSF49464 3117 3192 2.28E-6 T 29-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SUPERFAMILY SSF49373 2490 2585 1.46E-19 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Pfam PF02369 Bacterial Ig-like domain (group 1) 760 849 1.1E-7 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Pfam PF02369 Bacterial Ig-like domain (group 1) 872 952 4.1E-10 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Pfam PF02369 Bacterial Ig-like domain (group 1) 3006 3092 1.6E-9 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SUPERFAMILY SSF49373 2898 2993 3.53E-20 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Pfam PF09134 Invasin, domain 3 1675 1771 5.5E-24 T 29-03-2018 IPR015217 Invasin, domain 3 MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Pfam PF09134 Invasin, domain 3 2899 2994 3.3E-23 T 29-03-2018 IPR015217 Invasin, domain 3 MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Pfam PF09134 Invasin, domain 3 1166 1262 8.1E-25 T 29-03-2018 IPR015217 Invasin, domain 3 MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Pfam PF09134 Invasin, domain 3 2593 2690 3.8E-25 T 29-03-2018 IPR015217 Invasin, domain 3 MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Pfam PF09134 Invasin, domain 3 2287 2383 1.4E-23 T 29-03-2018 IPR015217 Invasin, domain 3 MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Pfam PF09134 Invasin, domain 3 2492 2588 4.7E-25 T 29-03-2018 IPR015217 Invasin, domain 3 MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Pfam PF09134 Invasin, domain 3 1573 1670 1.1E-22 T 29-03-2018 IPR015217 Invasin, domain 3 MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Pfam PF09134 Invasin, domain 3 1879 1975 3.1E-24 T 29-03-2018 IPR015217 Invasin, domain 3 MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Pfam PF09134 Invasin, domain 3 2185 2282 2.4E-23 T 29-03-2018 IPR015217 Invasin, domain 3 MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Pfam PF09134 Invasin, domain 3 1980 2076 3.1E-24 T 29-03-2018 IPR015217 Invasin, domain 3 MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Pfam PF09134 Invasin, domain 3 1268 1364 2.9E-26 T 29-03-2018 IPR015217 Invasin, domain 3 MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Pfam PF09134 Invasin, domain 3 2695 2792 6.3E-22 T 29-03-2018 IPR015217 Invasin, domain 3 MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Pfam PF09134 Invasin, domain 3 2389 2484 8.0E-24 T 29-03-2018 IPR015217 Invasin, domain 3 MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Pfam PF09134 Invasin, domain 3 1471 1567 8.5E-23 T 29-03-2018 IPR015217 Invasin, domain 3 MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Pfam PF09134 Invasin, domain 3 1777 1874 2.6E-23 T 29-03-2018 IPR015217 Invasin, domain 3 MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Pfam PF09134 Invasin, domain 3 2797 2894 1.1E-25 T 29-03-2018 IPR015217 Invasin, domain 3 MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Pfam PF09134 Invasin, domain 3 1369 1466 1.1E-24 T 29-03-2018 IPR015217 Invasin, domain 3 MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Pfam PF09134 Invasin, domain 3 2083 2180 4.6E-27 T 29-03-2018 IPR015217 Invasin, domain 3 MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Pfam PF09134 Invasin, domain 3 1062 1160 5.1E-25 T 29-03-2018 IPR015217 Invasin, domain 3 MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SUPERFAMILY SSF49373 2388 2482 2.12E-19 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SUPERFAMILY SSF49373 1266 1361 1.46E-20 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Pfam PF11924 Inverse autotransporter, beta-domain 166 438 2.0E-97 T 29-03-2018 IPR024519 Inverse autotransporter, beta-domain MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SUPERFAMILY SSF49373 1468 1565 1.2E-19 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SUPERFAMILY SSF49373 1981 2074 1.39E-19 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Gene3D G3DSA:2.60.40.1120 3040 3102 0.0011 T 29-03-2018 MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SUPERFAMILY SSF49373 755 853 3.92E-15 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SUPERFAMILY SSF49373 1368 1463 7.59E-20 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SUPERFAMILY SSF49373 1571 1665 3.14E-19 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SUPERFAMILY SSF49373 657 755 2.75E-14 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SUPERFAMILY SSF49373 1878 1973 9.94E-20 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SMART SM00634 1575 1663 1.4E-13 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SMART SM00634 2697 2785 6.1E-13 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SMART SM00634 1881 1969 4.7E-16 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SMART SM00634 1677 1765 8.0E-16 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SMART SM00634 1269 1357 5.5E-17 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SMART SM00634 2799 2887 1.2E-18 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SMART SM00634 2901 2987 4.5E-14 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SMART SM00634 1779 1867 8.2E-14 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SMART SM00634 1371 1459 3.2E-14 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SMART SM00634 2595 2683 6.4E-15 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SMART SM00634 763 854 4.2E-6 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SMART SM00634 2391 2478 6.1E-16 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SMART SM00634 960 1054 1.2E-6 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SMART SM00634 665 754 5.7E-5 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SMART SM00634 1983 2071 1.4E-13 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SMART SM00634 3001 3096 1.3E-4 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SMART SM00634 2085 2173 1.4E-14 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SMART SM00634 2289 2377 2.2E-15 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SMART SM00634 1473 1561 3.4E-14 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SMART SM00634 1167 1255 1.8E-18 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SMART SM00634 1065 1153 4.3E-14 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SMART SM00634 552 655 0.073 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SMART SM00634 2493 2581 1.8E-11 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SMART SM00634 865 954 3.9E-11 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SMART SM00634 2187 2275 1.4E-15 T 29-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SUPERFAMILY SSF49373 2693 2787 3.4E-18 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SUPERFAMILY SSF49373 2082 2177 7.59E-20 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SUPERFAMILY SSF49373 2182 2277 6.02E-19 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 SUPERFAMILY SSF49373 1672 1769 1.07E-19 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS02880 8d321542e2825f14078b5d9c19f93994 3343 Gene3D G3DSA:2.60.40.1120 3107 3194 1.5E-9 T 29-03-2018 MC49_RS15110 109c43350bedc7f821387b22dc322239 862 SUPERFAMILY SSF56712 3 606 5.49E-202 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain MC49_RS15110 109c43350bedc7f821387b22dc322239 862 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 306 320 - T 29-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 MC49_RS15110 109c43350bedc7f821387b22dc322239 862 Gene3D G3DSA:2.70.20.10 343 470 4.1E-38 T 29-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 MC49_RS15110 109c43350bedc7f821387b22dc322239 862 Gene3D G3DSA:3.30.65.10 697 741 6.4E-10 T 29-03-2018 MC49_RS15110 109c43350bedc7f821387b22dc322239 862 Gene3D G3DSA:3.30.65.10 644 696 0.033 T 29-03-2018 MC49_RS15110 109c43350bedc7f821387b22dc322239 862 Gene3D G3DSA:3.30.65.10 742 804 1.5E-9 T 29-03-2018 MC49_RS15110 109c43350bedc7f821387b22dc322239 862 Gene3D G3DSA:3.30.65.10 574 641 1.9E-10 T 29-03-2018 MC49_RS15110 109c43350bedc7f821387b22dc322239 862 Pfam PF08272 Topoisomerase I zinc-ribbon-like 755 790 5.3E-13 T 29-03-2018 IPR013263 DNA topoisomerase I, zinc ribbon-like, bacterial-type GO:0003677|GO:0003917|GO:0006265 MC49_RS15110 109c43350bedc7f821387b22dc322239 862 Pfam PF08272 Topoisomerase I zinc-ribbon-like 821 860 1.3E-22 T 29-03-2018 IPR013263 DNA topoisomerase I, zinc ribbon-like, bacterial-type GO:0003677|GO:0003917|GO:0006265 MC49_RS15110 109c43350bedc7f821387b22dc322239 862 SMART SM00493 3 130 3.7E-29 T 29-03-2018 IPR006171 TOPRIM domain MC49_RS15110 109c43350bedc7f821387b22dc322239 862 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 311 320 5.5E-37 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MC49_RS15110 109c43350bedc7f821387b22dc322239 862 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 387 403 5.5E-37 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MC49_RS15110 109c43350bedc7f821387b22dc322239 862 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 104 117 5.5E-37 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MC49_RS15110 109c43350bedc7f821387b22dc322239 862 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 189 207 5.5E-37 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MC49_RS15110 109c43350bedc7f821387b22dc322239 862 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 487 501 5.5E-37 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MC49_RS15110 109c43350bedc7f821387b22dc322239 862 SMART SM00436 131 219 5.8E-48 T 29-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 MC49_RS15110 109c43350bedc7f821387b22dc322239 862 Pfam PF01751 Toprim domain 5 140 3.3E-32 T 29-03-2018 IPR006171 TOPRIM domain MC49_RS15110 109c43350bedc7f821387b22dc322239 862 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 631 1.5E-252 T 29-03-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 MC49_RS15110 109c43350bedc7f821387b22dc322239 862 Gene3D G3DSA:1.10.460.10 162 342 6.6E-47 T 29-03-2018 MC49_RS15110 109c43350bedc7f821387b22dc322239 862 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 720 54.666 T 29-03-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 MC49_RS15110 109c43350bedc7f821387b22dc322239 862 Gene3D G3DSA:3.40.50.140 1 161 6.0E-48 T 29-03-2018 MC49_RS15110 109c43350bedc7f821387b22dc322239 862 SUPERFAMILY SSF57783 699 740 2.04E-7 T 29-03-2018 MC49_RS15110 109c43350bedc7f821387b22dc322239 862 Gene3D G3DSA:2.20.25.10 806 860 1.3E-29 T 29-03-2018 MC49_RS15110 109c43350bedc7f821387b22dc322239 862 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 705 742 9.2E-12 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 MC49_RS15110 109c43350bedc7f821387b22dc322239 862 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 595 619 1.6E-4 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 MC49_RS15110 109c43350bedc7f821387b22dc322239 862 SMART SM00437 269 524 1.9E-117 T 29-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 MC49_RS15110 109c43350bedc7f821387b22dc322239 862 SUPERFAMILY SSF57783 741 804 1.87E-19 T 29-03-2018 MC49_RS15110 109c43350bedc7f821387b22dc322239 862 SUPERFAMILY SSF57783 806 860 3.91E-22 T 29-03-2018 MC49_RS15110 109c43350bedc7f821387b22dc322239 862 Pfam PF01131 DNA topoisomerase 155 562 4.7E-129 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MC49_RS14915 6ee187e1de60eaa169ce82ba9dbc5e99 537 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 309 324 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MC49_RS14915 6ee187e1de60eaa169ce82ba9dbc5e99 537 Gene3D G3DSA:3.40.50.300 212 444 5.5E-36 T 29-03-2018 MC49_RS14915 6ee187e1de60eaa169ce82ba9dbc5e99 537 TIGRFAM TIGR02329 propionate_PrpR: propionate catabolism operon regulatory protein PrpR 4 530 1.3E-222 T 29-03-2018 IPR012704 Signal transduction response regulator, propionate catabolism, transcriptional regulator PrpR GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0005737|GO:0019629 MC49_RS14915 6ee187e1de60eaa169ce82ba9dbc5e99 537 SUPERFAMILY SSF159800 7 190 1.05E-50 T 29-03-2018 MC49_RS14915 6ee187e1de60eaa169ce82ba9dbc5e99 537 Pfam PF02954 Bacterial regulatory protein, Fis family 502 531 5.0E-8 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MC49_RS14915 6ee187e1de60eaa169ce82ba9dbc5e99 537 SUPERFAMILY SSF46689 440 531 5.97E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS14915 6ee187e1de60eaa169ce82ba9dbc5e99 537 Gene3D G3DSA:3.40.50.2300 1 92 9.5E-21 T 29-03-2018 MC49_RS14915 6ee187e1de60eaa169ce82ba9dbc5e99 537 Pfam PF06506 Propionate catabolism activator 30 192 9.8E-49 T 29-03-2018 IPR010524 Signal transduction response regulator, propionate catabolism activator, N-terminal GO:0000156|GO:0000160|GO:0003677|GO:0005524 MC49_RS14915 6ee187e1de60eaa169ce82ba9dbc5e99 537 Pfam PF00158 Sigma-54 interaction domain 214 389 2.0E-63 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MC49_RS14915 6ee187e1de60eaa169ce82ba9dbc5e99 537 Gene3D G3DSA:3.40.50.10660 93 172 3.9E-24 T 29-03-2018 MC49_RS14915 6ee187e1de60eaa169ce82ba9dbc5e99 537 Gene3D G3DSA:1.10.10.60 445 533 1.5E-12 T 29-03-2018 MC49_RS14915 6ee187e1de60eaa169ce82ba9dbc5e99 537 SUPERFAMILY SSF52540 213 458 1.86E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS14915 6ee187e1de60eaa169ce82ba9dbc5e99 537 Gene3D G3DSA:1.20.5.170 173 211 1.6E-12 T 29-03-2018 MC49_RS14915 6ee187e1de60eaa169ce82ba9dbc5e99 537 SMART SM00382 234 386 1.0E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 PRINTS PR01159 DNA gyrase subunit B signature 196 209 6.2E-77 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 PRINTS PR01159 DNA gyrase subunit B signature 773 789 6.2E-77 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 PRINTS PR01159 DNA gyrase subunit B signature 470 479 6.2E-77 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 PRINTS PR01159 DNA gyrase subunit B signature 757 769 6.2E-77 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 PRINTS PR01159 DNA gyrase subunit B signature 360 374 6.2E-77 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 PRINTS PR01159 DNA gyrase subunit B signature 5 15 6.2E-77 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 PRINTS PR01159 DNA gyrase subunit B signature 181 196 6.2E-77 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 PRINTS PR01159 DNA gyrase subunit B signature 220 242 6.2E-77 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 PRINTS PR01159 DNA gyrase subunit B signature 312 328 6.2E-77 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 PRINTS PR01159 DNA gyrase subunit B signature 374 394 6.2E-77 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 Gene3D G3DSA:3.30.565.10 17 220 1.0E-75 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 Pfam PF00204 DNA gyrase B 221 390 1.6E-59 T 29-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 Pfam PF01751 Toprim domain 419 531 9.8E-18 T 29-03-2018 IPR006171 TOPRIM domain MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 32 173 1.5E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 SUPERFAMILY SSF54211 221 392 3.22E-60 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 PRINTS PR00418 DNA topoisomerase II family signature 487 503 1.7E-70 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 PRINTS PR00418 DNA topoisomerase II family signature 113 127 1.7E-70 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 PRINTS PR00418 DNA topoisomerase II family signature 505 522 1.7E-70 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 PRINTS PR00418 DNA topoisomerase II family signature 736 752 1.7E-70 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 PRINTS PR00418 DNA topoisomerase II family signature 268 281 1.7E-70 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 PRINTS PR00418 DNA topoisomerase II family signature 35 50 1.7E-70 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 PRINTS PR00418 DNA topoisomerase II family signature 70 83 1.7E-70 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 PRINTS PR00418 DNA topoisomerase II family signature 525 537 1.7E-70 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 PRINTS PR00418 DNA topoisomerase II family signature 420 434 1.7E-70 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 SMART SM00433 35 797 1.8E-272 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 2 804 107.418 T 29-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 SUPERFAMILY SSF55874 4 220 7.33E-76 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 5 804 0.0 T 29-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 SUPERFAMILY SSF56719 730 795 4.71E-87 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 SUPERFAMILY SSF56719 394 560 4.71E-87 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 ProSitePatterns PS00177 DNA topoisomerase II signature. 422 430 - T 29-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 SMART SM00387 31 175 4.3E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 733 793 6.3E-31 T 29-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 Gene3D G3DSA:3.40.50.670 402 801 3.9E-108 T 29-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MC49_RS05320 5111cca5dd0fd24a726f6a4b468e4ea1 804 Gene3D G3DSA:3.30.230.10 221 392 4.9E-65 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MC49_RS00850 0639214499ae4a6441f1585ba1ce318c 329 Gene3D G3DSA:3.30.1330.10 1 142 4.5E-31 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MC49_RS00850 0639214499ae4a6441f1585ba1ce318c 329 SUPERFAMILY SSF56042 143 305 1.32E-38 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MC49_RS00850 0639214499ae4a6441f1585ba1ce318c 329 Gene3D G3DSA:3.90.650.10 145 322 2.5E-46 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MC49_RS00850 0639214499ae4a6441f1585ba1ce318c 329 Pfam PF02769 AIR synthase related protein, C-terminal domain 151 301 2.3E-10 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MC49_RS00850 0639214499ae4a6441f1585ba1ce318c 329 SUPERFAMILY SSF55326 4 138 6.11E-32 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MC49_RS00850 0639214499ae4a6441f1585ba1ce318c 329 PIRSF PIRSF005303 1 322 1.0E-87 T 29-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 MC49_RS00850 0639214499ae4a6441f1585ba1ce318c 329 Pfam PF00586 AIR synthase related protein, N-terminal domain 29 138 4.3E-21 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MC49_RS00850 0639214499ae4a6441f1585ba1ce318c 329 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 4 322 3.2E-110 T 29-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 MC49_RS00850 0639214499ae4a6441f1585ba1ce318c 329 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 3 319 31.424 T 29-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 MC49_RS01455 41eed98b2618ac8bdb778a695f1a9dab 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 33.82 T 29-03-2018 IPR023035 Ribosomal protein S9, bacterial/plastid MC49_RS01455 41eed98b2618ac8bdb778a695f1a9dab 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 2.3E-46 T 29-03-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 MC49_RS01455 41eed98b2618ac8bdb778a695f1a9dab 130 Gene3D G3DSA:3.30.230.10 3 130 7.6E-53 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MC49_RS01455 41eed98b2618ac8bdb778a695f1a9dab 130 SUPERFAMILY SSF54211 5 130 7.97E-49 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MC49_RS01455 41eed98b2618ac8bdb778a695f1a9dab 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 29-03-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 MC49_RS01545 79755a34eba561d094961ec77e69d02d 267 Gene3D G3DSA:3.40.50.300 5 251 4.5E-65 T 29-03-2018 MC49_RS01545 79755a34eba561d094961ec77e69d02d 267 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS01545 79755a34eba561d094961ec77e69d02d 267 Pfam PF00005 ABC transporter 25 172 5.2E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS01545 79755a34eba561d094961ec77e69d02d 267 SUPERFAMILY SSF52540 7 236 1.69E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS01545 79755a34eba561d094961ec77e69d02d 267 SMART SM00382 33 228 1.0E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS05945 2610e05beee845f3cf8ded46d76c5337 257 Pfam PF00696 Amino acid kinase family 4 234 9.7E-39 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MC49_RS05945 2610e05beee845f3cf8ded46d76c5337 257 Hamap MF_00082_B Acetylglutamate kinase [argB]. 1 257 25.063 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MC49_RS05945 2610e05beee845f3cf8ded46d76c5337 257 Gene3D G3DSA:3.40.1160.10 2 257 1.9E-40 T 29-03-2018 MC49_RS05945 2610e05beee845f3cf8ded46d76c5337 257 SUPERFAMILY SSF53633 2 256 6.81E-57 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MC49_RS05945 2610e05beee845f3cf8ded46d76c5337 257 TIGRFAM TIGR00761 argB: acetylglutamate kinase 4 233 1.3E-68 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MC49_RS05945 2610e05beee845f3cf8ded46d76c5337 257 PIRSF PIRSF000728 1 257 1.6E-69 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MC49_RS04075 c4ebfc8c58ddbd93b59661bf5e789d90 166 Pfam PF03719 Ribosomal protein S5, C-terminal domain 87 157 3.0E-30 T 29-03-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 MC49_RS04075 c4ebfc8c58ddbd93b59661bf5e789d90 166 SUPERFAMILY SSF54768 9 75 1.57E-23 T 29-03-2018 MC49_RS04075 c4ebfc8c58ddbd93b59661bf5e789d90 166 Pfam PF00333 Ribosomal protein S5, N-terminal domain 11 74 6.3E-29 T 29-03-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 MC49_RS04075 c4ebfc8c58ddbd93b59661bf5e789d90 166 Gene3D G3DSA:3.30.160.20 10 71 1.7E-27 T 29-03-2018 MC49_RS04075 c4ebfc8c58ddbd93b59661bf5e789d90 166 Gene3D G3DSA:3.30.230.10 76 166 2.2E-34 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MC49_RS04075 c4ebfc8c58ddbd93b59661bf5e789d90 166 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 163 34.563 T 29-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 MC49_RS04075 c4ebfc8c58ddbd93b59661bf5e789d90 166 SUPERFAMILY SSF54211 79 159 3.79E-27 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MC49_RS04075 c4ebfc8c58ddbd93b59661bf5e789d90 166 ProSitePatterns PS00585 Ribosomal protein S5 signature. 28 60 - T 29-03-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site MC49_RS04075 c4ebfc8c58ddbd93b59661bf5e789d90 166 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 10 163 2.3E-70 T 29-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 MC49_RS05675 1bcd0b53674ba5dd3b71965826645763 594 SUPERFAMILY SSF56235 1 221 6.86E-59 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MC49_RS05675 1bcd0b53674ba5dd3b71965826645763 594 Pfam PF13537 Glutamine amidotransferase domain 48 165 7.5E-42 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain MC49_RS05675 1bcd0b53674ba5dd3b71965826645763 594 Gene3D G3DSA:3.40.50.620 219 589 2.5E-64 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS05675 1bcd0b53674ba5dd3b71965826645763 594 Pfam PF00733 Asparagine synthase 239 585 3.5E-89 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 MC49_RS05675 1bcd0b53674ba5dd3b71965826645763 594 Gene3D G3DSA:3.60.20.10 1 218 4.1E-52 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MC49_RS05675 1bcd0b53674ba5dd3b71965826645763 594 PIRSF PIRSF001589 1 593 3.8E-163 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 MC49_RS05675 1bcd0b53674ba5dd3b71965826645763 594 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 520 6.2E-133 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 MC49_RS05675 1bcd0b53674ba5dd3b71965826645763 594 SUPERFAMILY SSF52402 230 377 2.15E-71 T 29-03-2018 MC49_RS05675 1bcd0b53674ba5dd3b71965826645763 594 SUPERFAMILY SSF52402 440 575 2.15E-71 T 29-03-2018 MC49_RS17765 f0a19060c90df37cbcaaa245c39355af 456 Gene3D G3DSA:3.40.50.300 157 444 1.0E-48 T 29-03-2018 MC49_RS17765 f0a19060c90df37cbcaaa245c39355af 456 Pfam PF03796 DnaB-like helicase C terminal domain 175 422 8.1E-73 T 29-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 MC49_RS17765 f0a19060c90df37cbcaaa245c39355af 456 Gene3D G3DSA:1.10.860.10 1 140 3.6E-16 T 29-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal MC49_RS17765 f0a19060c90df37cbcaaa245c39355af 456 SUPERFAMILY SSF52540 269 421 6.46E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS17765 f0a19060c90df37cbcaaa245c39355af 456 SUPERFAMILY SSF52540 175 242 6.46E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS17765 f0a19060c90df37cbcaaa245c39355af 456 SUPERFAMILY SSF48024 5 105 1.31E-13 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 MC49_RS17765 f0a19060c90df37cbcaaa245c39355af 456 Pfam PF00772 DnaB-like helicase N terminal domain 4 97 3.3E-11 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 MC49_RS09595 af2057da9cd9f2a19868d674dc03e5de 318 SUPERFAMILY SSF53807 40 304 2.67E-52 T 29-03-2018 MC49_RS09595 af2057da9cd9f2a19868d674dc03e5de 318 Gene3D G3DSA:3.40.50.1980 31 158 2.8E-23 T 29-03-2018 MC49_RS09595 af2057da9cd9f2a19868d674dc03e5de 318 Pfam PF01497 Periplasmic binding protein 68 295 3.4E-22 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 MC49_RS09595 af2057da9cd9f2a19868d674dc03e5de 318 Gene3D G3DSA:3.40.50.1980 159 318 1.9E-23 T 29-03-2018 MC49_RS12600 aab68e997f21faac83a21afb0e541a71 136 PRINTS PR00956 Flagellar motor switch protein FliN signature 55 71 7.5E-30 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 MC49_RS12600 aab68e997f21faac83a21afb0e541a71 136 PRINTS PR00956 Flagellar motor switch protein FliN signature 88 101 7.5E-30 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 MC49_RS12600 aab68e997f21faac83a21afb0e541a71 136 PRINTS PR00956 Flagellar motor switch protein FliN signature 72 88 7.5E-30 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 MC49_RS12600 aab68e997f21faac83a21afb0e541a71 136 PRINTS PR00956 Flagellar motor switch protein FliN signature 101 116 7.5E-30 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 MC49_RS12600 aab68e997f21faac83a21afb0e541a71 136 SUPERFAMILY SSF101801 53 134 1.31E-26 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) MC49_RS12600 aab68e997f21faac83a21afb0e541a71 136 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 53 127 3.4E-33 T 29-03-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 MC49_RS12600 aab68e997f21faac83a21afb0e541a71 136 Gene3D G3DSA:2.30.330.10 41 136 2.0E-30 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) MC49_RS12600 aab68e997f21faac83a21afb0e541a71 136 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 55 125 1.8E-25 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) MC49_RS13900 5c0d0cfb52473abc78a74ba46b39367d 321 SMART SM01400 10 127 1.5E-74 T 29-03-2018 MC49_RS13900 5c0d0cfb52473abc78a74ba46b39367d 321 Gene3D G3DSA:3.40.50.2020 7 158 1.1E-65 T 29-03-2018 MC49_RS13900 5c0d0cfb52473abc78a74ba46b39367d 321 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 10 320 49.609 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 MC49_RS13900 5c0d0cfb52473abc78a74ba46b39367d 321 SUPERFAMILY SSF53271 75 312 4.3E-67 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like MC49_RS13900 5c0d0cfb52473abc78a74ba46b39367d 321 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 135 150 - T 29-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 MC49_RS13900 5c0d0cfb52473abc78a74ba46b39367d 321 Gene3D G3DSA:3.40.50.2020 159 313 9.5E-43 T 29-03-2018 MC49_RS13900 5c0d0cfb52473abc78a74ba46b39367d 321 Pfam PF14572 Phosphoribosyl synthetase-associated domain 210 319 1.4E-30 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 MC49_RS13900 5c0d0cfb52473abc78a74ba46b39367d 321 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 10 320 2.3E-126 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 MC49_RS13900 5c0d0cfb52473abc78a74ba46b39367d 321 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 10 127 5.2E-49 T 29-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 MC49_RS13010 f71ea9afc81f03ebb640b3e4a7edd56f 309 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 5 299 3.1E-77 T 29-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 MC49_RS13010 f71ea9afc81f03ebb640b3e4a7edd56f 309 Hamap MF_01942 Lipid A biosynthesis lauroyltransferase [lpxL]. 4 308 43.68 T 29-03-2018 IPR011920 Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase GO:0009245|GO:0016021|GO:0016740 KEGG: 00600+2.3.1.24 MC49_RS13010 f71ea9afc81f03ebb640b3e4a7edd56f 309 TIGRFAM TIGR02207 lipid_A_htrB: lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase 6 308 3.1E-111 T 29-03-2018 IPR011920 Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase GO:0009245|GO:0016021|GO:0016740 KEGG: 00600+2.3.1.24 MC49_RS13010 f71ea9afc81f03ebb640b3e4a7edd56f 309 PIRSF PIRSF026649 3 308 3.3E-81 T 29-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 MC49_RS08305 bb59441658e1b99589920fafec775cda 312 SUPERFAMILY SSF46689 31 80 5.38E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS08305 bb59441658e1b99589920fafec775cda 312 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 83 125 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MC49_RS08305 bb59441658e1b99589920fafec775cda 312 Gene3D G3DSA:1.10.10.60 83 144 1.1E-13 T 29-03-2018 MC49_RS08305 bb59441658e1b99589920fafec775cda 312 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 98 113 5.0E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MC49_RS08305 bb59441658e1b99589920fafec775cda 312 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 113 129 5.0E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MC49_RS08305 bb59441658e1b99589920fafec775cda 312 SUPERFAMILY SSF46689 82 137 1.43E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS08305 bb59441658e1b99589920fafec775cda 312 Pfam PF12833 Helix-turn-helix domain 52 131 1.5E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MC49_RS08305 bb59441658e1b99589920fafec775cda 312 SUPERFAMILY SSF55136 150 311 4.71E-19 T 29-03-2018 MC49_RS08305 bb59441658e1b99589920fafec775cda 312 Pfam PF14526 Integron-associated effector binding protein 155 311 9.6E-12 T 29-03-2018 IPR029441 Integron-associated effector binding protein MC49_RS08305 bb59441658e1b99589920fafec775cda 312 Gene3D G3DSA:3.20.80.10 145 311 1.1E-13 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain MC49_RS08305 bb59441658e1b99589920fafec775cda 312 Gene3D G3DSA:1.10.10.60 17 82 1.6E-12 T 29-03-2018 MC49_RS08305 bb59441658e1b99589920fafec775cda 312 SMART SM00342 46 129 6.2E-30 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MC49_RS10095 fff5ab065698b87b4fdd74d1b2b1d559 404 SUPERFAMILY SSF56601 17 293 3.72E-80 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MC49_RS10095 fff5ab065698b87b4fdd74d1b2b1d559 404 Gene3D G3DSA:2.60.410.10 312 384 4.1E-17 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MC49_RS10095 fff5ab065698b87b4fdd74d1b2b1d559 404 SUPERFAMILY SSF69189 293 386 1.02E-23 T 29-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MC49_RS10095 fff5ab065698b87b4fdd74d1b2b1d559 404 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 42 273 5.3E-98 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 MC49_RS10095 fff5ab065698b87b4fdd74d1b2b1d559 404 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 293 384 1.9E-23 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MC49_RS10095 fff5ab065698b87b4fdd74d1b2b1d559 404 Gene3D G3DSA:3.40.710.10 19 311 1.4E-53 T 29-03-2018 MC49_RS10095 fff5ab065698b87b4fdd74d1b2b1d559 404 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 73 84 3.8E-16 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MC49_RS10095 fff5ab065698b87b4fdd74d1b2b1d559 404 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 132 149 3.8E-16 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MC49_RS10095 fff5ab065698b87b4fdd74d1b2b1d559 404 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 159 172 3.8E-16 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MC49_RS10095 fff5ab065698b87b4fdd74d1b2b1d559 404 SMART SM00936 293 384 4.0E-31 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MC49_RS19135 b03cb7814657885cac9b53de2149fddf 493 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 19 445 3.4E-125 T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 MC49_RS19135 b03cb7814657885cac9b53de2149fddf 493 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 363 383 - T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 MC49_RS19135 b03cb7814657885cac9b53de2149fddf 493 Pfam PF00860 Permease family 23 415 5.1E-97 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 MC49_RS10400 3764939945bb95fb170adf5deec4b606 520 PIRSF PIRSF006446 1 332 3.2E-111 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 MC49_RS10400 3764939945bb95fb170adf5deec4b606 520 PIRSF PIRSF006446 354 519 4.2E-29 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 MC49_RS10400 3764939945bb95fb170adf5deec4b606 520 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 7 501 1.7E-170 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 MC49_RS14725 d4c81529fd1efb2c9ea83e34cc91b422 152 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 52 89 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 MC49_RS14725 d4c81529fd1efb2c9ea83e34cc91b422 152 Gene3D G3DSA:3.40.140.10 1 152 9.5E-36 T 29-03-2018 MC49_RS14725 d4c81529fd1efb2c9ea83e34cc91b422 152 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 100 1.5E-22 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain MC49_RS14725 d4c81529fd1efb2c9ea83e34cc91b422 152 SUPERFAMILY SSF53927 2 134 3.18E-40 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 MC49_RS14795 c063f32be6acfae3d0fd7b5b3920c7ab 285 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 6 265 3.8E-52 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 MC49_RS14795 c063f32be6acfae3d0fd7b5b3920c7ab 285 Pfam PF02567 Phenazine biosynthesis-like protein 11 264 1.8E-49 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 MC49_RS14795 c063f32be6acfae3d0fd7b5b3920c7ab 285 SUPERFAMILY SSF54506 5 283 2.68E-65 T 29-03-2018 MC49_RS14795 c063f32be6acfae3d0fd7b5b3920c7ab 285 PIRSF PIRSF016184 4 284 2.9E-69 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 MC49_RS14795 c063f32be6acfae3d0fd7b5b3920c7ab 285 Gene3D G3DSA:3.10.310.10 132 273 7.4E-29 T 29-03-2018 MC49_RS14795 c063f32be6acfae3d0fd7b5b3920c7ab 285 Gene3D G3DSA:3.10.310.10 2 131 3.1E-32 T 29-03-2018 MC49_RS09155 491ee4aee3138447c05eca246f53d5c1 268 Hamap MF_01000 Vitamin B12-binding protein [btuF]. 3 268 44.903 T 29-03-2018 IPR023544 ABC transporter, vitamin B12-binding protein GO:0015889|GO:0031419|GO:0042597 MC49_RS09155 491ee4aee3138447c05eca246f53d5c1 268 Gene3D G3DSA:3.40.50.1980 144 268 3.7E-18 T 29-03-2018 MC49_RS09155 491ee4aee3138447c05eca246f53d5c1 268 SUPERFAMILY SSF53807 24 265 1.1E-52 T 29-03-2018 MC49_RS09155 491ee4aee3138447c05eca246f53d5c1 268 Pfam PF01497 Periplasmic binding protein 27 220 3.2E-25 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 MC49_RS09155 491ee4aee3138447c05eca246f53d5c1 268 Gene3D G3DSA:3.40.50.1980 23 143 8.0E-28 T 29-03-2018 MC49_RS09405 9efa870d1e7a92d92a2bf115a45c5d22 305 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 2 304 5.5E-102 T 29-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 MC49_RS09405 9efa870d1e7a92d92a2bf115a45c5d22 305 Pfam PF00753 Metallo-beta-lactamase superfamily 31 106 4.7E-8 T 29-03-2018 IPR001279 Metallo-beta-lactamase MC49_RS09405 9efa870d1e7a92d92a2bf115a45c5d22 305 SUPERFAMILY SSF56281 1 304 8.91E-80 T 29-03-2018 IPR001279 Metallo-beta-lactamase MC49_RS09405 9efa870d1e7a92d92a2bf115a45c5d22 305 Gene3D G3DSA:3.60.15.10 1 305 2.3E-57 T 29-03-2018 IPR001279 Metallo-beta-lactamase MC49_RS09405 9efa870d1e7a92d92a2bf115a45c5d22 305 Hamap MF_01818 Ribonuclease BN [rbn]. 1 305 38.702 T 29-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 MC49_RS15050 a68c0b23a9d713075a2617e918e8a40d 213 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 167 1.2E-18 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MC49_RS15050 a68c0b23a9d713075a2617e918e8a40d 213 ProSitePatterns PS01155 Endonuclease III family signature. 102 131 - T 29-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 MC49_RS15050 a68c0b23a9d713075a2617e918e8a40d 213 Pfam PF00633 Helix-hairpin-helix motif 100 127 3.3E-7 T 29-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 MC49_RS15050 a68c0b23a9d713075a2617e918e8a40d 213 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 187 203 7.7E-5 T 29-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 MC49_RS15050 a68c0b23a9d713075a2617e918e8a40d 213 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 187 203 - T 29-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 MC49_RS15050 a68c0b23a9d713075a2617e918e8a40d 213 Gene3D G3DSA:1.10.340.30 21 117 4.1E-24 T 29-03-2018 MC49_RS15050 a68c0b23a9d713075a2617e918e8a40d 213 Hamap MF_00942 Endonuclease III [nth]. 1 209 36.439 T 29-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 MC49_RS15050 a68c0b23a9d713075a2617e918e8a40d 213 SMART SM00525 186 206 3.7E-5 T 29-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 MC49_RS15050 a68c0b23a9d713075a2617e918e8a40d 213 TIGRFAM TIGR01083 nth: endonuclease III 4 194 4.6E-86 T 29-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 MC49_RS15050 a68c0b23a9d713075a2617e918e8a40d 213 PIRSF PIRSF001435 1 211 1.5E-48 T 29-03-2018 MC49_RS15050 a68c0b23a9d713075a2617e918e8a40d 213 SUPERFAMILY SSF48150 2 206 3.61E-71 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 MC49_RS15050 a68c0b23a9d713075a2617e918e8a40d 213 SMART SM00478 38 185 1.1E-51 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MC49_RS15050 a68c0b23a9d713075a2617e918e8a40d 213 Gene3D G3DSA:1.10.1670.10 118 213 8.6E-30 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 MC49_RS04575 dd60f4b43a40c8ab39ab4c76eee66d5d 257 Pfam PF07729 FCD domain 100 225 2.7E-22 T 29-03-2018 IPR011711 GntR, C-terminal MC49_RS04575 dd60f4b43a40c8ab39ab4c76eee66d5d 257 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 77 1.2E-22 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MC49_RS04575 dd60f4b43a40c8ab39ab4c76eee66d5d 257 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 9.2E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MC49_RS04575 dd60f4b43a40c8ab39ab4c76eee66d5d 257 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 9.2E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MC49_RS04575 dd60f4b43a40c8ab39ab4c76eee66d5d 257 SUPERFAMILY SSF48008 98 234 1.86E-27 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MC49_RS04575 dd60f4b43a40c8ab39ab4c76eee66d5d 257 SUPERFAMILY SSF46785 5 104 5.03E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS04575 dd60f4b43a40c8ab39ab4c76eee66d5d 257 SMART SM00345 18 77 1.1E-23 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MC49_RS04575 dd60f4b43a40c8ab39ab4c76eee66d5d 257 Gene3D G3DSA:1.10.10.10 6 79 1.1E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS04575 dd60f4b43a40c8ab39ab4c76eee66d5d 257 SMART SM00895 100 226 2.6E-23 T 29-03-2018 IPR011711 GntR, C-terminal MC49_RS04575 dd60f4b43a40c8ab39ab4c76eee66d5d 257 Gene3D G3DSA:1.20.120.530 96 241 5.4E-27 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MC49_RS05935 79a1717d5ebdaa01cfdea32b0e9bc4d2 386 Gene3D G3DSA:3.30.70.360 184 302 3.1E-22 T 29-03-2018 MC49_RS05935 79a1717d5ebdaa01cfdea32b0e9bc4d2 386 Pfam PF01546 Peptidase family M20/M25/M40 76 378 2.5E-31 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 MC49_RS05935 79a1717d5ebdaa01cfdea32b0e9bc4d2 386 Hamap MF_01108 Acetylornithine deacetylase [argE]. 3 382 64.389 T 29-03-2018 IPR010169 Acetylornithine deacetylase ArgE GO:0005737|GO:0006526|GO:0008777 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154 MC49_RS05935 79a1717d5ebdaa01cfdea32b0e9bc4d2 386 SUPERFAMILY SSF55031 181 294 1.5E-22 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain MC49_RS05935 79a1717d5ebdaa01cfdea32b0e9bc4d2 386 Gene3D G3DSA:3.40.630.10 1 183 2.9E-30 T 29-03-2018 MC49_RS05935 79a1717d5ebdaa01cfdea32b0e9bc4d2 386 SUPERFAMILY SSF53187 2 180 5.14E-57 T 29-03-2018 MC49_RS05935 79a1717d5ebdaa01cfdea32b0e9bc4d2 386 SUPERFAMILY SSF53187 305 381 5.14E-57 T 29-03-2018 MC49_RS05935 79a1717d5ebdaa01cfdea32b0e9bc4d2 386 Pfam PF07687 Peptidase dimerisation domain 178 288 1.1E-25 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain MC49_RS05935 79a1717d5ebdaa01cfdea32b0e9bc4d2 386 TIGRFAM TIGR01892 AcOrn-deacetyl: acetylornithine deacetylase (ArgE) 10 377 6.7E-150 T 29-03-2018 IPR010169 Acetylornithine deacetylase ArgE GO:0005737|GO:0006526|GO:0008777 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154 MC49_RS05935 79a1717d5ebdaa01cfdea32b0e9bc4d2 386 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 110 147 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 MC49_RS05935 79a1717d5ebdaa01cfdea32b0e9bc4d2 386 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 75 84 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 MC49_RS10955 21f50492af357c9f67efe144ab695b97 202 Pfam PF01569 PAP2 superfamily 65 169 4.6E-9 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MC49_RS10955 21f50492af357c9f67efe144ab695b97 202 Gene3D G3DSA:1.20.144.10 2 182 3.4E-18 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MC49_RS10955 21f50492af357c9f67efe144ab695b97 202 SUPERFAMILY SSF48317 3 201 6.93E-28 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MC49_RS10955 21f50492af357c9f67efe144ab695b97 202 SMART SM00014 61 169 5.5E-11 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MC49_RS02680 aacc5245b6c85fff41f8d317a9dc6630 424 PIRSF PIRSF001434 1 424 5.5E-130 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MC49_RS02680 aacc5245b6c85fff41f8d317a9dc6630 424 Gene3D G3DSA:3.40.640.10 1 287 3.1E-66 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS02680 aacc5245b6c85fff41f8d317a9dc6630 424 SUPERFAMILY SSF53383 1 421 3.55E-131 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS02680 aacc5245b6c85fff41f8d317a9dc6630 424 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 420 9.2E-146 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MC49_RS02680 aacc5245b6c85fff41f8d317a9dc6630 424 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 2 420 3.2E-208 T 29-03-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 MC49_RS02680 aacc5245b6c85fff41f8d317a9dc6630 424 Gene3D G3DSA:3.90.1150.10 289 424 3.2E-48 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS02680 aacc5245b6c85fff41f8d317a9dc6630 424 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 196 210 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MC49_RS09430 417be61c5e246363141eec5f09dbd5cd 417 Gene3D G3DSA:1.20.1250.20 199 416 1.3E-21 T 29-03-2018 MC49_RS09430 417be61c5e246363141eec5f09dbd5cd 417 Pfam PF03825 Nucleoside H+ symporter 1 407 8.3E-166 T 29-03-2018 MC49_RS09430 417be61c5e246363141eec5f09dbd5cd 417 Gene3D G3DSA:1.20.1250.20 5 181 1.5E-8 T 29-03-2018 MC49_RS09430 417be61c5e246363141eec5f09dbd5cd 417 TIGRFAM TIGR00889 2A0110: nucleoside transporter 1 416 2.8E-189 T 29-03-2018 IPR004740 Nucleoside:H+ symporter GO:0005337|GO:0015858|GO:0016021 MC49_RS09430 417be61c5e246363141eec5f09dbd5cd 417 SUPERFAMILY SSF103473 9 408 7.46E-32 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS11900 b21fa94f44544ddf6cc6ef06d1c272f0 485 Pfam PF06812 ImpA, N-terminal, type VI secretion system 14 111 3.3E-11 T 29-03-2018 IPR010657 ImpA, N-terminal MC49_RS11900 b21fa94f44544ddf6cc6ef06d1c272f0 485 TIGRFAM TIGR03362 VI_chp_7: type VI secretion-associated protein, VC_A0119 family 8 472 2.0E-119 T 29-03-2018 IPR017739 Type VI secretion system-associated, VCA0119 MC49_RS11900 b21fa94f44544ddf6cc6ef06d1c272f0 485 Pfam PF16989 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ 229 472 3.8E-71 T 29-03-2018 IPR017739 Type VI secretion system-associated, VCA0119 MC49_RS04340 cfefc6bfd12c081e219e4c13f8ab48c5 256 PIRSF PIRSF003107 7 226 4.1E-67 T 29-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 MC49_RS04340 cfefc6bfd12c081e219e4c13f8ab48c5 256 SUPERFAMILY SSF109755 13 230 4.4E-70 T 29-03-2018 MC49_RS04340 cfefc6bfd12c081e219e4c13f8ab48c5 256 Pfam PF01895 PhoU domain 128 212 9.3E-17 T 29-03-2018 IPR026022 PhoU domain MC49_RS04340 cfefc6bfd12c081e219e4c13f8ab48c5 256 Pfam PF01895 PhoU domain 27 111 1.4E-20 T 29-03-2018 IPR026022 PhoU domain MC49_RS04340 cfefc6bfd12c081e219e4c13f8ab48c5 256 Gene3D G3DSA:1.20.58.220 120 243 4.6E-26 T 29-03-2018 MC49_RS04340 cfefc6bfd12c081e219e4c13f8ab48c5 256 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 13 221 3.4E-73 T 29-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 MC49_RS04340 cfefc6bfd12c081e219e4c13f8ab48c5 256 Gene3D G3DSA:1.20.58.220 6 119 8.0E-28 T 29-03-2018 MC49_RS15375 f5b77ad5a360f476a7cb561b852b3dc4 282 SUPERFAMILY SSF53328 88 281 1.19E-57 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MC49_RS15375 f5b77ad5a360f476a7cb561b852b3dc4 282 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 6 282 45.332 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 MC49_RS15375 f5b77ad5a360f476a7cb561b852b3dc4 282 Pfam PF01842 ACT domain 10 71 6.3E-8 T 29-03-2018 IPR002912 ACT domain MC49_RS15375 f5b77ad5a360f476a7cb561b852b3dc4 282 SUPERFAMILY SSF55021 9 69 1.33E-8 T 29-03-2018 MC49_RS15375 f5b77ad5a360f476a7cb561b852b3dc4 282 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 9 282 3.5E-125 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 MC49_RS15375 f5b77ad5a360f476a7cb561b852b3dc4 282 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 88 110 9.3E-64 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 MC49_RS15375 f5b77ad5a360f476a7cb561b852b3dc4 282 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 256 281 9.3E-64 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 MC49_RS15375 f5b77ad5a360f476a7cb561b852b3dc4 282 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 234 256 9.3E-64 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 MC49_RS15375 f5b77ad5a360f476a7cb561b852b3dc4 282 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 110 137 9.3E-64 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 MC49_RS15375 f5b77ad5a360f476a7cb561b852b3dc4 282 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 43 55 9.3E-64 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 MC49_RS15375 f5b77ad5a360f476a7cb561b852b3dc4 282 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 11 37 9.3E-64 T 29-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 MC49_RS15375 f5b77ad5a360f476a7cb561b852b3dc4 282 Gene3D G3DSA:3.40.50.170 91 282 5.8E-51 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MC49_RS15375 f5b77ad5a360f476a7cb561b852b3dc4 282 Gene3D G3DSA:3.30.70.260 3 90 3.5E-13 T 29-03-2018 MC49_RS15375 f5b77ad5a360f476a7cb561b852b3dc4 282 PIRSF PIRSF036480 6 282 2.2E-112 T 29-03-2018 MC49_RS15375 f5b77ad5a360f476a7cb561b852b3dc4 282 Pfam PF00551 Formyl transferase 88 264 2.5E-50 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MC49_RS01665 38516bb481f139f873d3b0f1ca3c68dc 203 SUPERFAMILY SSF52972 2 183 7.85E-59 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MC49_RS01665 38516bb481f139f873d3b0f1ca3c68dc 203 Hamap MF_00528 Septum formation protein Maf [maf]. 3 189 30.22 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 MC49_RS01665 38516bb481f139f873d3b0f1ca3c68dc 203 Pfam PF02545 Maf-like protein 4 184 1.7E-56 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 MC49_RS01665 38516bb481f139f873d3b0f1ca3c68dc 203 PIRSF PIRSF006305 1 191 1.5E-48 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 MC49_RS01665 38516bb481f139f873d3b0f1ca3c68dc 203 TIGRFAM TIGR00172 maf: septum formation protein Maf 3 182 5.6E-57 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 MC49_RS01665 38516bb481f139f873d3b0f1ca3c68dc 203 Gene3D G3DSA:3.90.950.10 1 188 5.1E-66 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MC49_RS01930 c8fd969dba5e8c995e458455de5db9c9 600 SUPERFAMILY SSF56425 227 358 4.49E-43 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MC49_RS01930 c8fd969dba5e8c995e458455de5db9c9 600 Gene3D G3DSA:3.50.50.60 2 270 1.4E-41 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS01930 c8fd969dba5e8c995e458455de5db9c9 600 TIGRFAM TIGR01176 fum_red_Fp: fumarate reductase (quinol), flavoprotein subunit 3 582 0.0 T 29-03-2018 IPR005884 Fumarate reductase, flavoprotein subunit GO:0009061|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.4|KEGG: 00620+1.3.5.4|KEGG: 00650+1.3.5.4|KEGG: 00720+1.3.5.4|MetaCyc: PWY-5392|MetaCyc: PWY-5913|MetaCyc: PWY-7384 MC49_RS01930 c8fd969dba5e8c995e458455de5db9c9 600 PIRSF PIRSF000171 1 574 7.2E-43 T 29-03-2018 MC49_RS01930 c8fd969dba5e8c995e458455de5db9c9 600 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 7 581 1.1E-245 T 29-03-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MC49_RS01930 c8fd969dba5e8c995e458455de5db9c9 600 Gene3D G3DSA:1.20.58.100 423 538 4.7E-28 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MC49_RS01930 c8fd969dba5e8c995e458455de5db9c9 600 Gene3D G3DSA:3.50.50.60 283 413 3.0E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS01930 c8fd969dba5e8c995e458455de5db9c9 600 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 375 382 1.8E-5 T 29-03-2018 MC49_RS01930 c8fd969dba5e8c995e458455de5db9c9 600 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 1.8E-5 T 29-03-2018 MC49_RS01930 c8fd969dba5e8c995e458455de5db9c9 600 Gene3D G3DSA:4.10.80.40 543 576 1.3E-11 T 29-03-2018 MC49_RS01930 c8fd969dba5e8c995e458455de5db9c9 600 Pfam PF02910 Fumarate reductase flavoprotein C-term 453 581 6.8E-38 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MC49_RS01930 c8fd969dba5e8c995e458455de5db9c9 600 SUPERFAMILY SSF46977 444 588 6.28E-45 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MC49_RS01930 c8fd969dba5e8c995e458455de5db9c9 600 SUPERFAMILY SSF51905 3 250 7.25E-73 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS01930 c8fd969dba5e8c995e458455de5db9c9 600 SUPERFAMILY SSF51905 361 420 7.25E-73 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS01930 c8fd969dba5e8c995e458455de5db9c9 600 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 43 52 - T 29-03-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MC49_RS01930 c8fd969dba5e8c995e458455de5db9c9 600 Pfam PF00890 FAD binding domain 7 397 5.2E-116 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MC49_RS01930 c8fd969dba5e8c995e458455de5db9c9 600 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 360 382 2.8E-10 T 29-03-2018 MC49_RS01930 c8fd969dba5e8c995e458455de5db9c9 600 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 2.8E-10 T 29-03-2018 MC49_RS05955 eb1e3e253402ce8e91f0b89b75ed7c71 459 Pfam PF14698 Argininosuccinate lyase C-terminal 364 431 1.4E-23 T 29-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MC49_RS05955 eb1e3e253402ce8e91f0b89b75ed7c71 459 ProSitePatterns PS00163 Fumarate lyases signature. 276 285 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 MC49_RS05955 eb1e3e253402ce8e91f0b89b75ed7c71 459 PRINTS PR00145 Argininosuccinate lyase family signature 194 210 1.7E-68 T 29-03-2018 MC49_RS05955 eb1e3e253402ce8e91f0b89b75ed7c71 459 PRINTS PR00145 Argininosuccinate lyase family signature 143 163 1.7E-68 T 29-03-2018 MC49_RS05955 eb1e3e253402ce8e91f0b89b75ed7c71 459 PRINTS PR00145 Argininosuccinate lyase family signature 276 292 1.7E-68 T 29-03-2018 MC49_RS05955 eb1e3e253402ce8e91f0b89b75ed7c71 459 PRINTS PR00145 Argininosuccinate lyase family signature 102 124 1.7E-68 T 29-03-2018 MC49_RS05955 eb1e3e253402ce8e91f0b89b75ed7c71 459 PRINTS PR00145 Argininosuccinate lyase family signature 232 256 1.7E-68 T 29-03-2018 MC49_RS05955 eb1e3e253402ce8e91f0b89b75ed7c71 459 PRINTS PR00145 Argininosuccinate lyase family signature 311 330 1.7E-68 T 29-03-2018 MC49_RS05955 eb1e3e253402ce8e91f0b89b75ed7c71 459 TIGRFAM TIGR00838 argH: argininosuccinate lyase 3 456 1.8E-207 T 29-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MC49_RS05955 eb1e3e253402ce8e91f0b89b75ed7c71 459 Hamap MF_00006 Argininosuccinate lyase [argH]. 2 454 40.825 T 29-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MC49_RS05955 eb1e3e253402ce8e91f0b89b75ed7c71 459 PRINTS PR00149 Fumarate lyase superfamily signature 148 166 1.9E-28 T 29-03-2018 IPR000362 Fumarate lyase family MC49_RS05955 eb1e3e253402ce8e91f0b89b75ed7c71 459 PRINTS PR00149 Fumarate lyase superfamily signature 103 121 1.9E-28 T 29-03-2018 IPR000362 Fumarate lyase family MC49_RS05955 eb1e3e253402ce8e91f0b89b75ed7c71 459 PRINTS PR00149 Fumarate lyase superfamily signature 232 259 1.9E-28 T 29-03-2018 IPR000362 Fumarate lyase family MC49_RS05955 eb1e3e253402ce8e91f0b89b75ed7c71 459 PRINTS PR00149 Fumarate lyase superfamily signature 276 292 1.9E-28 T 29-03-2018 IPR000362 Fumarate lyase family MC49_RS05955 eb1e3e253402ce8e91f0b89b75ed7c71 459 SUPERFAMILY SSF48557 3 455 2.2E-139 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 MC49_RS05955 eb1e3e253402ce8e91f0b89b75ed7c71 459 Gene3D G3DSA:1.10.40.30 376 433 1.8E-25 T 29-03-2018 MC49_RS05955 eb1e3e253402ce8e91f0b89b75ed7c71 459 Pfam PF00206 Lyase 6 301 7.1E-97 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal MC49_RS05955 eb1e3e253402ce8e91f0b89b75ed7c71 459 Gene3D G3DSA:1.10.275.10 2 107 1.6E-32 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal MC49_RS05955 eb1e3e253402ce8e91f0b89b75ed7c71 459 Gene3D G3DSA:1.20.200.10 108 375 3.4E-93 T 29-03-2018 MC49_RS05580 2cb9d1e4b9cd0104f7d05d874f10315f 161 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 4 157 1.0E-56 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MC49_RS05580 2cb9d1e4b9cd0104f7d05d874f10315f 161 Pfam PF01467 Cytidylyltransferase-like 6 133 1.6E-22 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MC49_RS05580 2cb9d1e4b9cd0104f7d05d874f10315f 161 Gene3D G3DSA:3.40.50.620 1 159 2.3E-32 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS05580 2cb9d1e4b9cd0104f7d05d874f10315f 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 21 42 2.9E-46 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MC49_RS05580 2cb9d1e4b9cd0104f7d05d874f10315f 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 3 21 2.9E-46 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MC49_RS05580 2cb9d1e4b9cd0104f7d05d874f10315f 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 50 74 2.9E-46 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MC49_RS05580 2cb9d1e4b9cd0104f7d05d874f10315f 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 86 102 2.9E-46 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MC49_RS05580 2cb9d1e4b9cd0104f7d05d874f10315f 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 113 135 2.9E-46 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MC49_RS05580 2cb9d1e4b9cd0104f7d05d874f10315f 161 SUPERFAMILY SSF52374 2 157 1.77E-42 T 29-03-2018 MC49_RS05580 2cb9d1e4b9cd0104f7d05d874f10315f 161 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 12 77 6.0E-4 T 29-03-2018 MC49_RS05580 2cb9d1e4b9cd0104f7d05d874f10315f 161 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 3 159 34.509 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MC49_RS05580 2cb9d1e4b9cd0104f7d05d874f10315f 161 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 62 1.2E-16 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MC49_RS04750 86411db366a36057d028d2748d91da7e 296 Gene3D G3DSA:1.10.287.480 188 232 2.4E-17 T 29-03-2018 IPR023212 Heat shock protein Hsp33, helix hairpin bin domain MC49_RS04750 86411db366a36057d028d2748d91da7e 296 Gene3D G3DSA:3.90.1280.10 233 288 3.0E-20 T 29-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 MC49_RS04750 86411db366a36057d028d2748d91da7e 296 Gene3D G3DSA:3.55.30.10 1 177 1.2E-63 T 29-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 MC49_RS04750 86411db366a36057d028d2748d91da7e 296 SUPERFAMILY SSF118352 232 288 1.44E-18 T 29-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 MC49_RS04750 86411db366a36057d028d2748d91da7e 296 Hamap MF_00117 33 kDa chaperonin [hslO]. 5 291 31.269 T 29-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 MC49_RS04750 86411db366a36057d028d2748d91da7e 296 PIRSF PIRSF005261 1 292 2.6E-73 T 29-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 MC49_RS04750 86411db366a36057d028d2748d91da7e 296 Pfam PF01430 Hsp33 protein 6 280 2.3E-86 T 29-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 MC49_RS04750 86411db366a36057d028d2748d91da7e 296 SUPERFAMILY SSF64397 6 239 6.54E-75 T 29-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 MC49_RS10510 2d1251a3cea543d551865665253144bb 272 Pfam PF02517 CAAX protease self-immunity 170 259 6.2E-18 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 MC49_RS14300 e6c84814e549a301a42dffdbb79a02c2 238 SUPERFAMILY SSF46785 158 231 3.63E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS14300 e6c84814e549a301a42dffdbb79a02c2 238 SMART SM00419 175 223 4.6E-5 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MC49_RS14300 e6c84814e549a301a42dffdbb79a02c2 238 Pfam PF00027 Cyclic nucleotide-binding domain 41 127 2.2E-12 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain MC49_RS14300 e6c84814e549a301a42dffdbb79a02c2 238 SUPERFAMILY SSF51206 16 154 1.1E-26 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like MC49_RS14300 e6c84814e549a301a42dffdbb79a02c2 238 Gene3D G3DSA:1.10.10.10 159 236 1.2E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS14300 e6c84814e549a301a42dffdbb79a02c2 238 Pfam PF13545 Crp-like helix-turn-helix domain 161 230 1.8E-13 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MC49_RS14300 e6c84814e549a301a42dffdbb79a02c2 238 SMART SM00100 22 141 1.3E-11 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain MC49_RS14300 e6c84814e549a301a42dffdbb79a02c2 238 Gene3D G3DSA:2.60.120.10 11 158 2.2E-24 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MC49_RS01585 c1c5765d1370bfea4d7edfcf3d6dfb67 478 Pfam PF04552 Sigma-54, DNA binding domain 318 476 4.5E-70 T 29-03-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding MC49_RS01585 c1c5765d1370bfea4d7edfcf3d6dfb67 478 PRINTS PR00045 Sigma-54 factor signature 187 204 1.8E-32 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 MC49_RS01585 c1c5765d1370bfea4d7edfcf3d6dfb67 478 PRINTS PR00045 Sigma-54 factor signature 393 404 1.8E-32 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 MC49_RS01585 c1c5765d1370bfea4d7edfcf3d6dfb67 478 PRINTS PR00045 Sigma-54 factor signature 377 389 1.8E-32 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 MC49_RS01585 c1c5765d1370bfea4d7edfcf3d6dfb67 478 PRINTS PR00045 Sigma-54 factor signature 451 469 1.8E-32 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 MC49_RS01585 c1c5765d1370bfea4d7edfcf3d6dfb67 478 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 365 384 - T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 MC49_RS01585 c1c5765d1370bfea4d7edfcf3d6dfb67 478 PIRSF PIRSF000774 1 478 3.2E-152 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 MC49_RS01585 c1c5765d1370bfea4d7edfcf3d6dfb67 478 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 9 475 2.1E-158 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 MC49_RS01585 c1c5765d1370bfea4d7edfcf3d6dfb67 478 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 4 49 5.6E-17 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 MC49_RS01585 c1c5765d1370bfea4d7edfcf3d6dfb67 478 Gene3D G3DSA:1.10.10.10 323 414 2.4E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS01585 c1c5765d1370bfea4d7edfcf3d6dfb67 478 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 456 463 - T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 MC49_RS01585 c1c5765d1370bfea4d7edfcf3d6dfb67 478 Pfam PF04963 Sigma-54 factor, core binding domain 115 304 3.5E-58 T 29-03-2018 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 MC49_RS12790 9123d8a9eeb2fbb47f504a3582ac4657 225 SUPERFAMILY SSF69593 21 207 3.92E-29 T 29-03-2018 MC49_RS12790 9123d8a9eeb2fbb47f504a3582ac4657 225 Pfam PF01553 Acyltransferase 30 170 4.6E-16 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MC49_RS12790 9123d8a9eeb2fbb47f504a3582ac4657 225 Gene3D G3DSA:3.40.1130.10 8 224 2.0E-30 T 29-03-2018 MC49_RS12790 9123d8a9eeb2fbb47f504a3582ac4657 225 SMART SM00563 41 174 9.8E-15 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MC49_RS12100 1a1779c1d5c715aee1b052e1cbe6b877 245 SUPERFAMILY SSF75217 4 168 1.31E-38 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases MC49_RS12100 1a1779c1d5c715aee1b052e1cbe6b877 245 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 1 243 6.0E-85 T 29-03-2018 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 MC49_RS12100 1a1779c1d5c715aee1b052e1cbe6b877 245 Pfam PF00588 SpoU rRNA Methylase family 5 154 4.7E-34 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MC49_RS12100 1a1779c1d5c715aee1b052e1cbe6b877 245 Gene3D G3DSA:3.40.1280.10 1 165 1.3E-43 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MC49_RS12100 1a1779c1d5c715aee1b052e1cbe6b877 245 PIRSF PIRSF004808 1 245 8.8E-77 T 29-03-2018 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 MC49_RS13945 5ba36b85e4e99bf43a64f38a0db0bf75 149 Pfam PF04191 Phospholipid methyltransferase 37 136 4.3E-12 T 29-03-2018 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 MC49_RS13945 5ba36b85e4e99bf43a64f38a0db0bf75 149 ProDom PD049902 METHYLTRANSFERASE TRANSFERASE PRECURSOR ISOPRENYLCYSTEINE SIGNAL CARBOXYL TRANSMEMBRANE MEMBRANE FAMILY XCC3183 104 149 5.0E-6 T 29-03-2018 MC49_RS02830 ec8173f07fa37052d364b6365d5ac44a 187 Pfam PF00578 AhpC/TSA family 10 133 6.7E-33 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MC49_RS02830 ec8173f07fa37052d364b6365d5ac44a 187 Gene3D G3DSA:3.30.1020.10 154 183 1.4E-9 T 29-03-2018 MC49_RS02830 ec8173f07fa37052d364b6365d5ac44a 187 TIGRFAM TIGR03137 AhpC: peroxiredoxin 1 187 2.2E-102 T 29-03-2018 IPR017559 Alkyl hydroperoxide reductase subunit C GO:0006979|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MC49_RS02830 ec8173f07fa37052d364b6365d5ac44a 187 Gene3D G3DSA:3.40.30.10 5 153 5.7E-32 T 29-03-2018 MC49_RS02830 ec8173f07fa37052d364b6365d5ac44a 187 SUPERFAMILY SSF52833 1 186 7.65E-54 T 29-03-2018 IPR012336 Thioredoxin-like fold MC49_RS02830 ec8173f07fa37052d364b6365d5ac44a 187 PIRSF PIRSF000239 2 187 5.7E-51 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MC49_RS02830 ec8173f07fa37052d364b6365d5ac44a 187 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 156 181 2.5E-6 T 29-03-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MC49_RS06100 77b688b2e1c0dea218698ca0390b0b74 302 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 9 292 6.6E-150 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MC49_RS06100 77b688b2e1c0dea218698ca0390b0b74 302 SUPERFAMILY SSF55681 8 292 8.29E-134 T 29-03-2018 MC49_RS06100 77b688b2e1c0dea218698ca0390b0b74 302 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 7 293 62.481 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MC49_RS06100 77b688b2e1c0dea218698ca0390b0b74 302 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 7 301 6.4E-176 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MC49_RS06100 77b688b2e1c0dea218698ca0390b0b74 302 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 82 102 5.6E-71 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MC49_RS06100 77b688b2e1c0dea218698ca0390b0b74 302 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 139 159 5.6E-71 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MC49_RS06100 77b688b2e1c0dea218698ca0390b0b74 302 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 113 137 5.6E-71 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MC49_RS06100 77b688b2e1c0dea218698ca0390b0b74 302 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 253 269 5.6E-71 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MC49_RS06100 77b688b2e1c0dea218698ca0390b0b74 302 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 162 177 5.6E-71 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MC49_RS06100 77b688b2e1c0dea218698ca0390b0b74 302 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 61 76 5.6E-71 T 29-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MC49_RS06100 77b688b2e1c0dea218698ca0390b0b74 302 Gene3D G3DSA:1.20.58.180 216 294 3.7E-32 T 29-03-2018 MC49_RS06100 77b688b2e1c0dea218698ca0390b0b74 302 Gene3D G3DSA:3.30.930.10 1 214 2.4E-87 T 29-03-2018 MC49_RS07130 4624e7fea6d2d0b53eaca8a249f25517 163 Gene3D G3DSA:2.30.30.30 108 159 0.0022 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 MC49_RS07130 4624e7fea6d2d0b53eaca8a249f25517 163 Pfam PF02357 Transcription termination factor nusG 2 96 1.3E-18 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MC49_RS07130 4624e7fea6d2d0b53eaca8a249f25517 163 Gene3D G3DSA:3.30.70.940 1 99 3.2E-17 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MC49_RS07130 4624e7fea6d2d0b53eaca8a249f25517 163 Hamap MF_00951 Transcription antitermination protein RfaH [rfaH]. 1 162 45.89 T 29-03-2018 IPR010215 Transcription antitermination protein RfaH GO:0006355 MC49_RS07130 4624e7fea6d2d0b53eaca8a249f25517 163 TIGRFAM TIGR01955 RfaH: transcription elongation factor/antiterminator RfaH 4 159 3.7E-59 T 29-03-2018 IPR010215 Transcription antitermination protein RfaH GO:0006355 MC49_RS07130 4624e7fea6d2d0b53eaca8a249f25517 163 SMART SM00738 1 100 7.1E-27 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MC49_RS07130 4624e7fea6d2d0b53eaca8a249f25517 163 SUPERFAMILY SSF82679 1 98 7.32E-28 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MC49_RS11430 599d6a3707b68699b519bab4a140b5ab 180 Gene3D G3DSA:2.60.40.1090 31 180 7.8E-30 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS11430 599d6a3707b68699b519bab4a140b5ab 180 SUPERFAMILY SSF49401 33 180 8.45E-32 T 29-03-2018 IPR008966 Adhesion domain MC49_RS11430 599d6a3707b68699b519bab4a140b5ab 180 Pfam PF00419 Fimbrial protein 40 180 3.4E-19 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS16315 c055df3d79f6617ec57e466e6a965d00 239 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 225 5.6E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MC49_RS16315 c055df3d79f6617ec57e466e6a965d00 239 SMART SM00862 150 226 9.2E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MC49_RS16315 c055df3d79f6617ec57e466e6a965d00 239 SMART SM00448 6 116 1.1E-37 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS16315 c055df3d79f6617ec57e466e6a965d00 239 SUPERFAMILY SSF46894 134 227 2.07E-25 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MC49_RS16315 c055df3d79f6617ec57e466e6a965d00 239 SUPERFAMILY SSF52172 7 128 8.25E-38 T 29-03-2018 IPR011006 CheY-like superfamily MC49_RS16315 c055df3d79f6617ec57e466e6a965d00 239 Gene3D G3DSA:1.10.10.10 129 232 8.8E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS16315 c055df3d79f6617ec57e466e6a965d00 239 Gene3D G3DSA:3.40.50.2300 5 128 5.9E-34 T 29-03-2018 MC49_RS16315 c055df3d79f6617ec57e466e6a965d00 239 Pfam PF00072 Response regulator receiver domain 8 117 3.8E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS16230 ec24078b6794950947a5d9d790addcea 208 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 208 44.477 T 29-03-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 MC49_RS16230 ec24078b6794950947a5d9d790addcea 208 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 2 208 1.2E-90 T 29-03-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 MC49_RS16230 ec24078b6794950947a5d9d790addcea 208 SUPERFAMILY SSF53271 3 206 3.58E-68 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like MC49_RS16230 ec24078b6794950947a5d9d790addcea 208 Pfam PF14681 Uracil phosphoribosyltransferase 7 207 9.9E-65 T 29-03-2018 MC49_RS16230 ec24078b6794950947a5d9d790addcea 208 Gene3D G3DSA:3.40.50.2020 1 206 1.6E-60 T 29-03-2018 MC49_RS18395 259e46823c11bd03d78dca3929757dc1 577 Pfam PF01368 DHH family 74 224 1.8E-9 T 29-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 MC49_RS18395 259e46823c11bd03d78dca3929757dc1 577 SUPERFAMILY SSF64182 48 466 2.88E-115 T 29-03-2018 MC49_RS18395 259e46823c11bd03d78dca3929757dc1 577 Gene3D G3DSA:3.90.1640.10 53 330 1.4E-23 T 29-03-2018 MC49_RS18395 259e46823c11bd03d78dca3929757dc1 577 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 25 573 3.0E-154 T 29-03-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 MC49_RS18395 259e46823c11bd03d78dca3929757dc1 577 Pfam PF02272 DHHA1 domain 322 452 2.7E-22 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 MC49_RS13180 e089deae3800a5cf7d35463c7d858b19 420 Gene3D G3DSA:3.30.70.270 114 171 1.3E-11 T 29-03-2018 MC49_RS13180 e089deae3800a5cf7d35463c7d858b19 420 Gene3D G3DSA:3.30.70.270 37 113 1.2E-16 T 29-03-2018 MC49_RS13180 e089deae3800a5cf7d35463c7d858b19 420 Pfam PF00817 impB/mucB/samB family 5 150 1.4E-38 T 29-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MC49_RS13180 e089deae3800a5cf7d35463c7d858b19 420 Pfam PF11798 IMS family HHH motif 172 199 1.6E-5 T 29-03-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 MC49_RS13180 e089deae3800a5cf7d35463c7d858b19 420 Gene3D G3DSA:3.30.1490.100 247 358 4.8E-21 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MC49_RS13180 e089deae3800a5cf7d35463c7d858b19 420 Gene3D G3DSA:1.10.150.20 172 246 8.2E-17 T 29-03-2018 MC49_RS13180 e089deae3800a5cf7d35463c7d858b19 420 Pfam PF13438 Domain of unknown function (DUF4113) 370 418 5.9E-17 T 29-03-2018 IPR025188 Domain of unknown function DUF4113 MC49_RS13180 e089deae3800a5cf7d35463c7d858b19 420 SUPERFAMILY SSF56672 1 236 1.16E-70 T 29-03-2018 MC49_RS13180 e089deae3800a5cf7d35463c7d858b19 420 Pfam PF11799 impB/mucB/samB family C-terminal domain 240 353 6.8E-16 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MC49_RS03200 b8eff8266d843b89b424100602d96a7d 528 Gene3D G3DSA:1.10.8.60 381 443 9.2E-12 T 29-03-2018 MC49_RS03200 b8eff8266d843b89b424100602d96a7d 528 Pfam PF00158 Sigma-54 interaction domain 191 358 5.3E-48 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MC49_RS03200 b8eff8266d843b89b424100602d96a7d 528 PIRSF PIRSF037354 4 527 1.1E-262 T 29-03-2018 IPR017183 Sigma54-dependent transcriptional activator, RtcR GO:0003700|GO:0006355 MC49_RS03200 b8eff8266d843b89b424100602d96a7d 528 SUPERFAMILY SSF52540 196 440 1.81E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS03200 b8eff8266d843b89b424100602d96a7d 528 Gene3D G3DSA:3.40.50.10770 23 156 1.3E-8 T 29-03-2018 MC49_RS03200 b8eff8266d843b89b424100602d96a7d 528 Pfam PF06956 Regulator of RNA terminal phosphate cyclase 5 188 8.4E-86 T 29-03-2018 IPR009715 Regulator of RNA terminal phosphate cyclase MC49_RS03200 b8eff8266d843b89b424100602d96a7d 528 Gene3D G3DSA:3.40.50.300 163 380 1.7E-28 T 29-03-2018 MC49_RS03200 b8eff8266d843b89b424100602d96a7d 528 SMART SM00382 210 355 1.1E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS08605 3f58c131e761ddcebfdc49f2580dde5d 453 Gene3D G3DSA:2.30.170.30 1 53 2.5E-26 T 29-03-2018 MC49_RS08605 3f58c131e761ddcebfdc49f2580dde5d 453 PIRSF PIRSF018788 1 453 2.7E-229 T 29-03-2018 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 MC49_RS08605 3f58c131e761ddcebfdc49f2580dde5d 453 Gene3D G3DSA:3.20.20.70 143 449 1.2E-152 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS08605 3f58c131e761ddcebfdc49f2580dde5d 453 Pfam PF06751 Ethanolamine ammonia lyase large subunit (EutB) 12 444 1.4E-202 T 29-03-2018 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 MC49_RS08605 3f58c131e761ddcebfdc49f2580dde5d 453 Gene3D G3DSA:1.10.220.70 56 140 6.3E-30 T 29-03-2018 MC49_RS10585 96ae41209d02bd6d0b5b3203dad1a524 264 TIGRFAM TIGR02072 BioC: malonyl-acyl carrier protein O-methyltransferase BioC 18 260 1.1E-62 T 29-03-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00670+2.1.1.19|KEGG: 00780+2.1.1.197|MetaCyc: PWY-2201|MetaCyc: PWY-6519 MC49_RS10585 96ae41209d02bd6d0b5b3203dad1a524 264 Pfam PF08241 Methyltransferase domain 59 150 1.8E-25 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 MC49_RS10585 96ae41209d02bd6d0b5b3203dad1a524 264 Hamap MF_00835 Malonyl-[acyl-carrier protein] O-methyltransferase [bioC]. 10 262 26.9 T 29-03-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00670+2.1.1.19|KEGG: 00780+2.1.1.197|MetaCyc: PWY-2201|MetaCyc: PWY-6519 MC49_RS10585 96ae41209d02bd6d0b5b3203dad1a524 264 SUPERFAMILY SSF53335 16 244 2.13E-36 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS10585 96ae41209d02bd6d0b5b3203dad1a524 264 Gene3D G3DSA:3.40.50.150 3 229 7.2E-32 T 29-03-2018 MC49_RS04825 0729e7698b801b99b779221fcdf59963 161 Gene3D G3DSA:3.30.1330.60 22 161 7.3E-23 T 29-03-2018 IPR006665 OmpA-like domain MC49_RS04825 0729e7698b801b99b779221fcdf59963 161 PRINTS PR01021 OMPA domain signature 83 98 2.5E-7 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MC49_RS04825 0729e7698b801b99b779221fcdf59963 161 PRINTS PR01021 OMPA domain signature 98 114 2.5E-7 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MC49_RS04825 0729e7698b801b99b779221fcdf59963 161 Pfam PF00691 OmpA family 48 137 6.3E-12 T 29-03-2018 IPR006665 OmpA-like domain MC49_RS04825 0729e7698b801b99b779221fcdf59963 161 SUPERFAMILY SSF103088 39 158 2.09E-20 T 29-03-2018 IPR006665 OmpA-like domain MC49_RS17100 2729c71acae0677a729b53e9b29472dc 310 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 291 7.8E-129 T 29-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 MC49_RS17100 2729c71acae0677a729b53e9b29472dc 310 Pfam PF00698 Acyl transferase domain 7 300 7.4E-38 T 29-03-2018 IPR014043 Acyl transferase MC49_RS17100 2729c71acae0677a729b53e9b29472dc 310 SUPERFAMILY SSF55048 128 197 4.05E-18 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 MC49_RS17100 2729c71acae0677a729b53e9b29472dc 310 Gene3D G3DSA:3.40.366.10 1 184 6.3E-54 T 29-03-2018 MC49_RS17100 2729c71acae0677a729b53e9b29472dc 310 Gene3D G3DSA:3.40.366.10 185 309 6.6E-30 T 29-03-2018 MC49_RS17100 2729c71acae0677a729b53e9b29472dc 310 PIRSF PIRSF000446 1 309 2.0E-139 T 29-03-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 MC49_RS17100 2729c71acae0677a729b53e9b29472dc 310 SUPERFAMILY SSF52151 4 122 7.06E-83 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MC49_RS17100 2729c71acae0677a729b53e9b29472dc 310 SUPERFAMILY SSF52151 190 308 7.06E-83 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MC49_RS17100 2729c71acae0677a729b53e9b29472dc 310 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 307 6.7E-44 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain MC49_RS05430 e8b779d5e373c7d179779f972fd3f15b 216 TIGRFAM TIGR01583 formate-DH-gamm: formate dehydrogenase, gamma subunit 8 206 2.3E-64 T 29-03-2018 IPR006471 Formate dehydrogenase, gamma subunit GO:0008863|GO:0009326|GO:0016021|GO:0045333 MC49_RS05430 e8b779d5e373c7d179779f972fd3f15b 216 Pfam PF01292 Prokaryotic cytochrome b561 11 186 9.2E-22 T 29-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 MC49_RS05430 e8b779d5e373c7d179779f972fd3f15b 216 SUPERFAMILY SSF81342 5 211 1.31E-53 T 29-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 MC49_RS05430 e8b779d5e373c7d179779f972fd3f15b 216 Gene3D G3DSA:1.20.950.20 3 216 1.4E-52 T 29-03-2018 MC49_RS14680 a0ae261322e2d1bc971ad74f6653f07e 329 SUPERFAMILY SSF53850 106 310 3.26E-37 T 29-03-2018 MC49_RS14680 a0ae261322e2d1bc971ad74f6653f07e 329 Gene3D G3DSA:3.40.190.10 193 277 8.5E-17 T 29-03-2018 MC49_RS14680 a0ae261322e2d1bc971ad74f6653f07e 329 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 20 79 2.7E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS14680 a0ae261322e2d1bc971ad74f6653f07e 329 Gene3D G3DSA:3.40.190.10 105 192 1.1E-6 T 29-03-2018 MC49_RS14680 a0ae261322e2d1bc971ad74f6653f07e 329 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 56 3.2E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS14680 a0ae261322e2d1bc971ad74f6653f07e 329 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 56 67 3.2E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS14680 a0ae261322e2d1bc971ad74f6653f07e 329 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 46 3.2E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS14680 a0ae261322e2d1bc971ad74f6653f07e 329 Pfam PF03466 LysR substrate binding domain 104 309 6.9E-31 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS14680 a0ae261322e2d1bc971ad74f6653f07e 329 SUPERFAMILY SSF46785 20 126 5.15E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS14680 a0ae261322e2d1bc971ad74f6653f07e 329 Gene3D G3DSA:1.10.10.10 14 98 8.1E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS19020 6659f28193ea553675e1a75737709760 345 SMART SM00829 10 342 5.6E-7 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MC49_RS19020 6659f28193ea553675e1a75737709760 345 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MC49_RS19020 6659f28193ea553675e1a75737709760 345 Gene3D G3DSA:3.90.180.10 1 148 2.5E-38 T 29-03-2018 MC49_RS19020 6659f28193ea553675e1a75737709760 345 SUPERFAMILY SSF51735 139 309 1.25E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS19020 6659f28193ea553675e1a75737709760 345 Pfam PF00107 Zinc-binding dehydrogenase 177 304 6.5E-20 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MC49_RS19020 6659f28193ea553675e1a75737709760 345 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 135 3.3E-25 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MC49_RS19020 6659f28193ea553675e1a75737709760 345 Gene3D G3DSA:3.40.50.720 149 334 1.5E-26 T 29-03-2018 MC49_RS19020 6659f28193ea553675e1a75737709760 345 SUPERFAMILY SSF50129 1 174 9.13E-50 T 29-03-2018 IPR011032 GroES-like MC49_RS01380 839bf7033677b4555d12068d1776dccd 298 Gene3D G3DSA:1.10.10.10 2 89 3.5E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS01380 839bf7033677b4555d12068d1776dccd 298 Pfam PF03466 LysR substrate binding domain 94 289 4.9E-17 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS01380 839bf7033677b4555d12068d1776dccd 298 Gene3D G3DSA:3.40.190.10 184 268 6.7E-8 T 29-03-2018 MC49_RS01380 839bf7033677b4555d12068d1776dccd 298 SUPERFAMILY SSF46785 4 115 1.83E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS01380 839bf7033677b4555d12068d1776dccd 298 Gene3D G3DSA:3.40.190.10 95 183 4.6E-8 T 29-03-2018 MC49_RS01380 839bf7033677b4555d12068d1776dccd 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 68 2.3E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS01380 839bf7033677b4555d12068d1776dccd 298 SUPERFAMILY SSF53850 93 290 1.5E-21 T 29-03-2018 MC49_RS18285 a7e24016cc72ca6ffef519e1d5050be0 253 Gene3D G3DSA:3.40.190.10 115 252 3.6E-14 T 29-03-2018 MC49_RS18285 a7e24016cc72ca6ffef519e1d5050be0 253 Gene3D G3DSA:3.40.190.10 23 114 3.2E-15 T 29-03-2018 MC49_RS18285 a7e24016cc72ca6ffef519e1d5050be0 253 SUPERFAMILY SSF53850 24 246 1.29E-44 T 29-03-2018 MC49_RS18285 a7e24016cc72ca6ffef519e1d5050be0 253 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 31 243 6.8E-23 T 29-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 MC49_RS18285 a7e24016cc72ca6ffef519e1d5050be0 253 PIRSF PIRSF004846 1 248 6.1E-44 T 29-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 MC49_RS18285 a7e24016cc72ca6ffef519e1d5050be0 253 Pfam PF13531 Bacterial extracellular solute-binding protein 25 244 8.5E-42 T 29-03-2018 MC49_RS18965 e11c80bce26e844ce843237f7e8663d1 421 Pfam PF01636 Phosphotransferase enzyme family 41 288 7.4E-18 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase MC49_RS18965 e11c80bce26e844ce843237f7e8663d1 421 Gene3D G3DSA:3.30.200.20 1 116 4.8E-32 T 29-03-2018 MC49_RS18965 e11c80bce26e844ce843237f7e8663d1 421 PIRSF PIRSF031134 4 420 1.7E-143 T 29-03-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|KEGG: 00500+2.7.1.10|MetaCyc: PWY-6754 MC49_RS18965 e11c80bce26e844ce843237f7e8663d1 421 Hamap MF_01683 Methylthioribose kinase [mtnK]. 1 421 171.44 T 29-03-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|KEGG: 00500+2.7.1.10|MetaCyc: PWY-6754 MC49_RS18965 e11c80bce26e844ce843237f7e8663d1 421 SUPERFAMILY SSF56112 8 414 2.19E-81 T 29-03-2018 IPR011009 Protein kinase-like domain MC49_RS18965 e11c80bce26e844ce843237f7e8663d1 421 Gene3D G3DSA:3.90.1200.10 117 392 2.6E-12 T 29-03-2018 MC49_RS18965 e11c80bce26e844ce843237f7e8663d1 421 TIGRFAM TIGR01767 MTRK: S-methyl-5-thioribose kinase 42 417 9.5E-123 T 29-03-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|KEGG: 00500+2.7.1.10|MetaCyc: PWY-6754 MC49_RS16765 b2cabdc964abb562cf5817371504ed96 445 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 11 445 2.8E-158 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 MC49_RS16765 b2cabdc964abb562cf5817371504ed96 445 PIRSF PIRSF002746 2 445 3.0E-136 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 MC49_RS16765 b2cabdc964abb562cf5817371504ed96 445 Pfam PF02447 GntP family permease 8 443 7.1E-151 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 MC49_RS01480 78d3b820da178fd1ef8c4ab1385b77ae 575 SUPERFAMILY SSF55124 346 424 1.8E-20 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MC49_RS01480 78d3b820da178fd1ef8c4ab1385b77ae 575 SUPERFAMILY SSF56014 150 341 6.94E-55 T 29-03-2018 MC49_RS01480 78d3b820da178fd1ef8c4ab1385b77ae 575 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 173 329 6.7E-46 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MC49_RS01480 78d3b820da178fd1ef8c4ab1385b77ae 575 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 433 558 0.44 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MC49_RS01480 78d3b820da178fd1ef8c4ab1385b77ae 575 SUPERFAMILY SSF56014 428 561 3.01E-32 T 29-03-2018 MC49_RS01480 78d3b820da178fd1ef8c4ab1385b77ae 575 TIGRFAM TIGR02041 CysI: sulfite reductase (NADPH) hemoprotein, beta-component 19 559 1.5E-285 T 29-03-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MC49_RS01480 78d3b820da178fd1ef8c4ab1385b77ae 575 Gene3D G3DSA:3.30.413.10 141 346 3.7E-45 T 29-03-2018 MC49_RS01480 78d3b820da178fd1ef8c4ab1385b77ae 575 Gene3D G3DSA:3.30.413.10 426 563 6.3E-24 T 29-03-2018 MC49_RS01480 78d3b820da178fd1ef8c4ab1385b77ae 575 PRINTS PR00397 Sirohaem Fe-binding site signature 430 448 2.7E-8 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MC49_RS01480 78d3b820da178fd1ef8c4ab1385b77ae 575 PRINTS PR00397 Sirohaem Fe-binding site signature 478 496 2.7E-8 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MC49_RS01480 78d3b820da178fd1ef8c4ab1385b77ae 575 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 478 494 - T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MC49_RS01480 78d3b820da178fd1ef8c4ab1385b77ae 575 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 80 140 2.4E-13 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MC49_RS01480 78d3b820da178fd1ef8c4ab1385b77ae 575 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 353 417 4.4E-13 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MC49_RS01480 78d3b820da178fd1ef8c4ab1385b77ae 575 Hamap MF_01540 Sulfite reductase [NADPH] hemoprotein beta-component [cysI]. 10 571 57.978 T 29-03-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MC49_RS01480 78d3b820da178fd1ef8c4ab1385b77ae 575 SUPERFAMILY SSF55124 13 145 1.06E-27 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MC49_RS18815 eb3ee316eec4535de1e384cc919d1136 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 256 2.2E-60 T 29-03-2018 MC49_RS18815 eb3ee316eec4535de1e384cc919d1136 259 Gene3D G3DSA:3.40.50.720 1 42 1.2E-11 T 29-03-2018 MC49_RS18815 eb3ee316eec4535de1e384cc919d1136 259 Gene3D G3DSA:3.40.50.720 43 259 1.1E-61 T 29-03-2018 MC49_RS18815 eb3ee316eec4535de1e384cc919d1136 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MC49_RS18815 eb3ee316eec4535de1e384cc919d1136 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.3E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS18815 eb3ee316eec4535de1e384cc919d1136 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.3E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS18815 eb3ee316eec4535de1e384cc919d1136 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.3E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS18815 eb3ee316eec4535de1e384cc919d1136 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.3E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS18815 eb3ee316eec4535de1e384cc919d1136 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 1.3E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS18815 eb3ee316eec4535de1e384cc919d1136 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.3E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS18815 eb3ee316eec4535de1e384cc919d1136 259 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 186 4.5E-4 T 29-03-2018 MC49_RS18815 eb3ee316eec4535de1e384cc919d1136 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 6.8E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS18815 eb3ee316eec4535de1e384cc919d1136 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 6.8E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS18815 eb3ee316eec4535de1e384cc919d1136 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 6.8E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS18815 eb3ee316eec4535de1e384cc919d1136 259 SUPERFAMILY SSF51735 5 257 2.15E-80 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS18815 eb3ee316eec4535de1e384cc919d1136 259 TIGRFAM TIGR02415 23BDH: acetoin reductases 6 259 1.3E-108 T 29-03-2018 IPR014007 Acetoin reductase GO:0019152|GO:0045150|GO:0055114 KEGG: 00072+1.1.1.30|KEGG: 00650+1.1.1.304+1.1.1.30|MetaCyc: PWY-6389 MC49_RS02030 fbceb390c80795f6126f430380b2145a 183 Pfam PF12838 4Fe-4S dicluster domain 39 89 2.3E-12 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MC49_RS02030 fbceb390c80795f6126f430380b2145a 183 Gene3D G3DSA:3.30.70.20 13 46 2.9E-7 T 29-03-2018 MC49_RS02030 fbceb390c80795f6126f430380b2145a 183 Gene3D G3DSA:3.30.70.20 47 81 1.1E-16 T 29-03-2018 MC49_RS02030 fbceb390c80795f6126f430380b2145a 183 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MC49_RS02030 fbceb390c80795f6126f430380b2145a 183 SUPERFAMILY SSF54862 18 118 3.03E-22 T 29-03-2018 MC49_RS02030 fbceb390c80795f6126f430380b2145a 183 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 75 86 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MC49_RS02030 fbceb390c80795f6126f430380b2145a 183 Gene3D G3DSA:3.30.70.20 82 163 7.5E-6 T 29-03-2018 MC49_RS16105 61566316ea7342063314daf9ab72ace4 150 Hamap MF_01874 UPF0756 membrane protein YeaL [yeaL]. 5 150 18.951 T 29-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame MC49_RS16105 61566316ea7342063314daf9ab72ace4 150 Pfam PF04284 Protein of unknown function (DUF441) 9 147 3.6E-47 T 29-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame MC49_RS16105 61566316ea7342063314daf9ab72ace4 150 ProDom PD021096 MEMBRANE YEAL PRECURSOR SIGNAL PROTEIN TRANSMEMBRANE YTWI HI1074 INTEGRAL SPANNING 5 132 5.0E-46 T 29-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame MC49_RS08110 9cb67fac92a64f0d82c90710a567d9d5 319 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 5 319 50.953 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MC49_RS08110 9cb67fac92a64f0d82c90710a567d9d5 319 Gene3D G3DSA:3.90.226.10 23 312 5.1E-69 T 29-03-2018 MC49_RS08110 9cb67fac92a64f0d82c90710a567d9d5 319 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 2 319 3.0E-169 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MC49_RS08110 9cb67fac92a64f0d82c90710a567d9d5 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 91 102 1.2E-49 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MC49_RS08110 9cb67fac92a64f0d82c90710a567d9d5 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 200 209 1.2E-49 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MC49_RS08110 9cb67fac92a64f0d82c90710a567d9d5 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 137 153 1.2E-49 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MC49_RS08110 9cb67fac92a64f0d82c90710a567d9d5 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 156 169 1.2E-49 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MC49_RS08110 9cb67fac92a64f0d82c90710a567d9d5 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 116 134 1.2E-49 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MC49_RS08110 9cb67fac92a64f0d82c90710a567d9d5 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 172 185 1.2E-49 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MC49_RS08110 9cb67fac92a64f0d82c90710a567d9d5 319 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 5 151 6.8E-63 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MC49_RS08110 9cb67fac92a64f0d82c90710a567d9d5 319 SUPERFAMILY SSF52096 5 318 3.95E-106 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MC49_RS02915 6ef062dea948cb1985d3c6ca78459679 580 Pfam PF07730 Histidine kinase 371 434 4.4E-17 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MC49_RS02915 6ef062dea948cb1985d3c6ca78459679 580 SMART SM00387 475 568 1.7E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS02915 6ef062dea948cb1985d3c6ca78459679 580 SUPERFAMILY SSF158472 172 222 1.09E-5 T 29-03-2018 MC49_RS02915 6ef062dea948cb1985d3c6ca78459679 580 Gene3D G3DSA:3.30.450.40 208 297 4.8E-6 T 29-03-2018 IPR029016 GAF domain-like MC49_RS02915 6ef062dea948cb1985d3c6ca78459679 580 Gene3D G3DSA:3.30.450.40 298 367 0.0094 T 29-03-2018 IPR029016 GAF domain-like MC49_RS02915 6ef062dea948cb1985d3c6ca78459679 580 PIRSF PIRSF003167 1 577 1.0E-171 T 29-03-2018 IPR016380 Signal transduction histidine kinase, nitrate/nitrite-sensing GO:0000155|GO:0000160|GO:0004673|GO:0016021 MC49_RS02915 6ef062dea948cb1985d3c6ca78459679 580 Pfam PF00672 HAMP domain 172 221 8.2E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MC49_RS02915 6ef062dea948cb1985d3c6ca78459679 580 SUPERFAMILY SSF55874 443 565 4.32E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS02915 6ef062dea948cb1985d3c6ca78459679 580 Pfam PF13675 Type IV pili methyl-accepting chemotaxis transducer N-term 33 122 7.6E-12 T 29-03-2018 IPR029095 NarX-like, N-terminal MC49_RS02915 6ef062dea948cb1985d3c6ca78459679 580 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 478 566 2.0E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS02915 6ef062dea948cb1985d3c6ca78459679 580 SMART SM00304 172 225 7.5E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MC49_RS02915 6ef062dea948cb1985d3c6ca78459679 580 Gene3D G3DSA:3.30.565.10 434 573 1.1E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS02490 d594f317bcb637b8484b3c1bd6763242 467 TIGRFAM TIGR00881 2A0104: phosphoglycerate transporter family protein 35 419 2.8E-143 T 29-03-2018 MC49_RS02490 d594f317bcb637b8484b3c1bd6763242 467 PIRSF PIRSF002808 6 454 6.7E-106 T 29-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 MC49_RS02490 d594f317bcb637b8484b3c1bd6763242 467 SUPERFAMILY SSF103473 20 437 3.92E-73 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS02490 d594f317bcb637b8484b3c1bd6763242 467 Gene3D G3DSA:1.20.1250.20 245 457 2.8E-28 T 29-03-2018 MC49_RS02490 d594f317bcb637b8484b3c1bd6763242 467 Gene3D G3DSA:1.20.1250.20 18 222 7.8E-35 T 29-03-2018 MC49_RS02490 d594f317bcb637b8484b3c1bd6763242 467 Pfam PF07690 Major Facilitator Superfamily 34 402 7.5E-44 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS02490 d594f317bcb637b8484b3c1bd6763242 467 ProSitePatterns PS00942 glpT family of transporters signature. 150 166 - T 29-03-2018 IPR021159 Glycerate/sugar phosphate transporter, conserved site GO:0005215|GO:0006810|GO:0016021 Reactome: R-HSA-70153 MC49_RS11110 fe968f2eeeb9c5bca98b5acced872fb1 593 TIGRFAM TIGR00702 TIGR00702: YcaO-type kinase domain 13 406 1.5E-158 T 29-03-2018 IPR003776 YcaO-like domain MC49_RS11110 fe968f2eeeb9c5bca98b5acced872fb1 593 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 61 393 1.5E-83 T 29-03-2018 IPR003776 YcaO-like domain MC49_RS04870 1772ee132b587195c50d77c5d0421075 335 Gene3D G3DSA:1.10.1220.10 286 331 2.7E-7 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 MC49_RS18325 e4ea73dadda5f5f5b3a66d51ef322d40 142 Pfam PF04657 Putative inner membrane exporter, YdcZ 6 137 7.9E-25 T 29-03-2018 IPR006750 Putative inner membrane exporter, YdcZ MC49_RS02400 6c7e4e47e089ccb491a018c3bf8b204d 128 Pfam PF00419 Fimbrial protein 7 127 4.7E-6 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS02400 6c7e4e47e089ccb491a018c3bf8b204d 128 SUPERFAMILY SSF49401 2 127 6.96E-23 T 29-03-2018 IPR008966 Adhesion domain MC49_RS02400 6c7e4e47e089ccb491a018c3bf8b204d 128 Gene3D G3DSA:2.60.40.1090 1 128 1.9E-22 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS00975 5b78777bbfc387ba500ec5ccd855f690 376 Pfam PF01924 Hydrogenase formation hypA family 12 373 2.3E-150 T 29-03-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 MC49_RS00975 5b78777bbfc387ba500ec5ccd855f690 376 PIRSF PIRSF005622 1 376 2.0E-152 T 29-03-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 MC49_RS00975 5b78777bbfc387ba500ec5ccd855f690 376 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 4 374 2.9E-155 T 29-03-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 MC49_RS04115 ee9e5a7e6d7e34abf55cbb821ba4653b 84 SUPERFAMILY SSF50249 5 82 2.1E-33 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS04115 ee9e5a7e6d7e34abf55cbb821ba4653b 84 ProSitePatterns PS00056 Ribosomal protein S17 signature. 56 68 - T 29-03-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04115 ee9e5a7e6d7e34abf55cbb821ba4653b 84 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 5 80 25.197 T 29-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS04115 ee9e5a7e6d7e34abf55cbb821ba4653b 84 PRINTS PR00973 Ribosomal protein S17 family signature 24 47 1.7E-13 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS04115 ee9e5a7e6d7e34abf55cbb821ba4653b 84 PRINTS PR00973 Ribosomal protein S17 family signature 56 66 1.7E-13 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS04115 ee9e5a7e6d7e34abf55cbb821ba4653b 84 PRINTS PR00973 Ribosomal protein S17 family signature 66 73 1.7E-13 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS04115 ee9e5a7e6d7e34abf55cbb821ba4653b 84 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 6 76 2.0E-33 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS04115 ee9e5a7e6d7e34abf55cbb821ba4653b 84 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 6 76 1.9E-38 T 29-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS04115 ee9e5a7e6d7e34abf55cbb821ba4653b 84 Gene3D G3DSA:2.40.50.140 5 82 9.5E-34 T 29-03-2018 MC49_RS04115 ee9e5a7e6d7e34abf55cbb821ba4653b 84 Pfam PF00366 Ribosomal protein S17 10 76 7.7E-34 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS01495 788090eec7510eb5c89351c1ce74393d 257 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS01495 788090eec7510eb5c89351c1ce74393d 257 SMART SM00382 30 211 2.7E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS01495 788090eec7510eb5c89351c1ce74393d 257 Gene3D G3DSA:3.40.50.300 1 256 1.4E-59 T 29-03-2018 MC49_RS01495 788090eec7510eb5c89351c1ce74393d 257 SUPERFAMILY SSF52540 4 217 1.82E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS01495 788090eec7510eb5c89351c1ce74393d 257 Pfam PF00005 ABC transporter 21 160 5.7E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS15740 376dcbde91b1ab539df2f0bfc955293b 341 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 1.4E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MC49_RS15740 376dcbde91b1ab539df2f0bfc955293b 341 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 1.4E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MC49_RS15740 376dcbde91b1ab539df2f0bfc955293b 341 Gene3D G3DSA:1.10.260.40 2 57 5.5E-20 T 29-03-2018 MC49_RS15740 376dcbde91b1ab539df2f0bfc955293b 341 SUPERFAMILY SSF47413 1 59 5.9E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS15740 376dcbde91b1ab539df2f0bfc955293b 341 SUPERFAMILY SSF53822 60 337 6.13E-97 T 29-03-2018 IPR028082 Periplasmic binding protein-like I MC49_RS15740 376dcbde91b1ab539df2f0bfc955293b 341 Gene3D G3DSA:3.40.50.2300 58 169 1.7E-27 T 29-03-2018 MC49_RS15740 376dcbde91b1ab539df2f0bfc955293b 341 Gene3D G3DSA:3.40.50.2300 170 334 8.3E-55 T 29-03-2018 MC49_RS15740 376dcbde91b1ab539df2f0bfc955293b 341 SMART SM00354 1 71 1.3E-36 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MC49_RS15740 376dcbde91b1ab539df2f0bfc955293b 341 Hamap MF_01277 HTH-type transcriptional repressor PurR [purR]. 1 335 60.759 T 29-03-2018 IPR023588 Transcription regulator HTH, PurR GO:0006355 MC49_RS15740 376dcbde91b1ab539df2f0bfc955293b 341 Pfam PF13377 Periplasmic binding protein-like domain 171 331 1.2E-43 T 29-03-2018 MC49_RS15740 376dcbde91b1ab539df2f0bfc955293b 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 4.2E-19 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MC49_RS15740 376dcbde91b1ab539df2f0bfc955293b 341 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 29-03-2018 MC49_RS03710 61a620129a3ac1996de5764f352ffd09 305 SUPERFAMILY SSF56349 114 298 2.06E-52 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MC49_RS03710 61a620129a3ac1996de5764f352ffd09 305 Pfam PF00589 Phage integrase family 118 286 1.3E-48 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MC49_RS03710 61a620129a3ac1996de5764f352ffd09 305 Gene3D G3DSA:1.10.443.10 119 294 1.5E-42 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MC49_RS03710 61a620129a3ac1996de5764f352ffd09 305 Gene3D G3DSA:1.10.150.130 1 118 1.7E-20 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal MC49_RS03710 61a620129a3ac1996de5764f352ffd09 305 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 14 95 6.9E-23 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 MC49_RS03710 61a620129a3ac1996de5764f352ffd09 305 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 14 302 2.5E-104 T 29-03-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 MC49_RS03710 61a620129a3ac1996de5764f352ffd09 305 SUPERFAMILY SSF47823 13 104 1.69E-10 T 29-03-2018 IPR010998 Integrase, Lambda-type, N-terminal MC49_RS03710 61a620129a3ac1996de5764f352ffd09 305 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 11 300 54.408 T 29-03-2018 IPR023009 Tyrosine recombinase XerC/XerD MC49_RS04735 9962ca837cb4c810e61d50944531324d 184 ProSitePatterns PS00893 Nudix box signature. 79 100 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MC49_RS04735 9962ca837cb4c810e61d50944531324d 184 SUPERFAMILY SSF55811 5 180 5.96E-36 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MC49_RS04735 9962ca837cb4c810e61d50944531324d 184 Gene3D G3DSA:3.90.79.10 7 184 1.0E-31 T 29-03-2018 MC49_RS04735 9962ca837cb4c810e61d50944531324d 184 Pfam PF00293 NUDIX domain 46 139 3.2E-12 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MC49_RS04745 d91924d8a3e7cd448df50a19ee7486cb 138 PIRSF PIRSF016821 8 135 3.1E-40 T 29-03-2018 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 MC49_RS04745 d91924d8a3e7cd448df50a19ee7486cb 138 SUPERFAMILY SSF55174 11 105 6.54E-29 T 29-03-2018 MC49_RS04745 d91924d8a3e7cd448df50a19ee7486cb 138 Gene3D G3DSA:3.10.290.10 4 107 1.4E-25 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MC49_RS04745 d91924d8a3e7cd448df50a19ee7486cb 138 Pfam PF01479 S4 domain 11 57 2.8E-13 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MC49_RS04745 d91924d8a3e7cd448df50a19ee7486cb 138 SMART SM00363 11 72 1.7E-9 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MC49_RS16735 19505f040987a082bf496d04221c3d26 430 SUPERFAMILY SSF53901 9 289 1.75E-59 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MC49_RS16735 19505f040987a082bf496d04221c3d26 430 Pfam PF00108 Thiolase, N-terminal domain 9 281 2.1E-63 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 MC49_RS16735 19505f040987a082bf496d04221c3d26 430 Gene3D G3DSA:3.40.47.10 294 427 3.8E-23 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MC49_RS16735 19505f040987a082bf496d04221c3d26 430 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 11 428 3.7E-125 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MC49_RS16735 19505f040987a082bf496d04221c3d26 430 Gene3D G3DSA:3.40.47.10 1 293 1.4E-43 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MC49_RS16735 19505f040987a082bf496d04221c3d26 430 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 89 107 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 MC49_RS16735 19505f040987a082bf496d04221c3d26 430 SUPERFAMILY SSF53901 291 428 1.58E-30 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MC49_RS16735 19505f040987a082bf496d04221c3d26 430 PIRSF PIRSF000429 3 430 2.7E-116 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MC49_RS16735 19505f040987a082bf496d04221c3d26 430 ProSitePatterns PS00099 Thiolases active site. 411 424 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 MC49_RS16735 19505f040987a082bf496d04221c3d26 430 Pfam PF02803 Thiolase, C-terminal domain 290 428 5.6E-33 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 MC49_RS16735 19505f040987a082bf496d04221c3d26 430 ProSitePatterns PS00737 Thiolases signature 2. 376 392 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 MC49_RS14065 f4297253a028e56f5a8dd00af7f05602 336 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 336 182.521 T 29-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 MC49_RS14065 f4297253a028e56f5a8dd00af7f05602 336 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 256 329 1.3E-33 T 29-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 MC49_RS14065 f4297253a028e56f5a8dd00af7f05602 336 SUPERFAMILY SSF52540 23 252 4.7E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS14065 f4297253a028e56f5a8dd00af7f05602 336 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 7 238 1.6E-116 T 29-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 MC49_RS14065 f4297253a028e56f5a8dd00af7f05602 336 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 253 330 8.0E-35 T 29-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 MC49_RS14065 f4297253a028e56f5a8dd00af7f05602 336 Gene3D G3DSA:3.40.50.300 21 184 1.5E-26 T 29-03-2018 MC49_RS14065 f4297253a028e56f5a8dd00af7f05602 336 Gene3D G3DSA:1.10.10.10 260 330 2.8E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS14065 f4297253a028e56f5a8dd00af7f05602 336 SUPERFAMILY SSF46785 260 331 6.12E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS14065 f4297253a028e56f5a8dd00af7f05602 336 SMART SM00382 54 181 1.5E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS14065 f4297253a028e56f5a8dd00af7f05602 336 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 27 329 4.7E-146 T 29-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 MC49_RS14065 f4297253a028e56f5a8dd00af7f05602 336 Gene3D G3DSA:1.10.8.60 187 257 1.9E-30 T 29-03-2018 MC49_RS05575 32db0fcffeb6a4c0164a4124b27d834d 269 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 114 4.0E-32 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 MC49_RS05575 32db0fcffeb6a4c0164a4124b27d834d 269 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 269 43.922 T 29-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 MC49_RS05575 32db0fcffeb6a4c0164a4124b27d834d 269 Gene3D G3DSA:1.10.8.50 131 269 1.4E-52 T 29-03-2018 MC49_RS05575 32db0fcffeb6a4c0164a4124b27d834d 269 SUPERFAMILY SSF81624 2 138 4.32E-43 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 MC49_RS05575 32db0fcffeb6a4c0164a4124b27d834d 269 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 129 218 1.2E-28 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 MC49_RS05575 32db0fcffeb6a4c0164a4124b27d834d 269 SMART SM01232 129 221 2.4E-52 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 MC49_RS05575 32db0fcffeb6a4c0164a4124b27d834d 269 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 268 1.5E-103 T 29-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 MC49_RS05575 32db0fcffeb6a4c0164a4124b27d834d 269 SMART SM00898 2 115 1.4E-51 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 MC49_RS05575 32db0fcffeb6a4c0164a4124b27d834d 269 ProSitePatterns PS01242 Zinc finger FPG-type signature. 243 268 - T 29-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 MC49_RS05575 32db0fcffeb6a4c0164a4124b27d834d 269 Gene3D G3DSA:3.20.190.10 2 130 6.8E-38 T 29-03-2018 MC49_RS05575 32db0fcffeb6a4c0164a4124b27d834d 269 SUPERFAMILY SSF46946 130 222 2.49E-32 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 MC49_RS05575 32db0fcffeb6a4c0164a4124b27d834d 269 SUPERFAMILY SSF57716 217 268 8.56E-16 T 29-03-2018 MC49_RS05575 32db0fcffeb6a4c0164a4124b27d834d 269 Pfam PF06827 Zinc finger found in FPG and IleRS 241 269 2.9E-9 T 29-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 MC49_RS14480 a19596d76785b3a135e5aa72f0d45ef4 898 Pfam PF00122 E1-E2 ATPase 142 348 8.0E-42 T 29-03-2018 MC49_RS14480 a19596d76785b3a135e5aa72f0d45ef4 898 SUPERFAMILY SSF56784 366 386 2.39E-36 T 29-03-2018 IPR023214 HAD-like domain MC49_RS14480 a19596d76785b3a135e5aa72f0d45ef4 898 SUPERFAMILY SSF56784 492 738 2.39E-36 T 29-03-2018 IPR023214 HAD-like domain MC49_RS14480 a19596d76785b3a135e5aa72f0d45ef4 898 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 370 376 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MC49_RS14480 a19596d76785b3a135e5aa72f0d45ef4 898 SUPERFAMILY SSF81653 147 268 5.1E-25 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 MC49_RS14480 a19596d76785b3a135e5aa72f0d45ef4 898 TIGRFAM TIGR01524 ATPase-IIIB_Mg: magnesium-translocating P-type ATPase 17 897 0.0 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MC49_RS14480 a19596d76785b3a135e5aa72f0d45ef4 898 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 263 403 4.2E-20 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MC49_RS14480 a19596d76785b3a135e5aa72f0d45ef4 898 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 604 727 7.0E-31 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MC49_RS14480 a19596d76785b3a135e5aa72f0d45ef4 898 SMART SM00831 23 96 4.3E-14 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 MC49_RS14480 a19596d76785b3a135e5aa72f0d45ef4 898 Pfam PF00702 haloacid dehalogenase-like hydrolase 364 652 6.6E-18 T 29-03-2018 MC49_RS14480 a19596d76785b3a135e5aa72f0d45ef4 898 Gene3D G3DSA:1.20.1110.10 542 893 9.3E-52 T 29-03-2018 MC49_RS14480 a19596d76785b3a135e5aa72f0d45ef4 898 SUPERFAMILY SSF81665 269 362 7.59E-98 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MC49_RS14480 a19596d76785b3a135e5aa72f0d45ef4 898 SUPERFAMILY SSF81665 687 894 7.59E-98 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MC49_RS14480 a19596d76785b3a135e5aa72f0d45ef4 898 SUPERFAMILY SSF81665 26 145 7.59E-98 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MC49_RS14480 a19596d76785b3a135e5aa72f0d45ef4 898 Pfam PF00690 Cation transporter/ATPase, N-terminus 25 91 1.8E-11 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 MC49_RS14480 a19596d76785b3a135e5aa72f0d45ef4 898 PRINTS PR01836 Magnesium-transporting ATPase signature 766 782 9.8E-86 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MC49_RS14480 a19596d76785b3a135e5aa72f0d45ef4 898 PRINTS PR01836 Magnesium-transporting ATPase signature 714 725 9.8E-86 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MC49_RS14480 a19596d76785b3a135e5aa72f0d45ef4 898 PRINTS PR01836 Magnesium-transporting ATPase signature 801 822 9.8E-86 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MC49_RS14480 a19596d76785b3a135e5aa72f0d45ef4 898 PRINTS PR01836 Magnesium-transporting ATPase signature 298 317 9.8E-86 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MC49_RS14480 a19596d76785b3a135e5aa72f0d45ef4 898 PRINTS PR01836 Magnesium-transporting ATPase signature 746 759 9.8E-86 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MC49_RS14480 a19596d76785b3a135e5aa72f0d45ef4 898 PRINTS PR01836 Magnesium-transporting ATPase signature 281 297 9.8E-86 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MC49_RS14480 a19596d76785b3a135e5aa72f0d45ef4 898 PRINTS PR01836 Magnesium-transporting ATPase signature 851 872 9.8E-86 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MC49_RS14480 a19596d76785b3a135e5aa72f0d45ef4 898 PRINTS PR01836 Magnesium-transporting ATPase signature 696 711 9.8E-86 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MC49_RS14480 a19596d76785b3a135e5aa72f0d45ef4 898 PRINTS PR01836 Magnesium-transporting ATPase signature 402 415 9.8E-86 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 MC49_RS14480 a19596d76785b3a135e5aa72f0d45ef4 898 Gene3D G3DSA:3.40.1110.10 326 541 5.5E-40 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MC49_RS14480 a19596d76785b3a135e5aa72f0d45ef4 898 Pfam PF00689 Cation transporting ATPase, C-terminus 721 887 7.6E-16 T 29-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 MC49_RS14480 a19596d76785b3a135e5aa72f0d45ef4 898 Gene3D G3DSA:2.70.150.10 33 270 3.2E-38 T 29-03-2018 MC49_RS19140 34cb9df5282d9c6fb6e53f3b221e6298 654 Gene3D G3DSA:3.30.70.20 66 95 6.0E-10 T 29-03-2018 MC49_RS19140 34cb9df5282d9c6fb6e53f3b221e6298 654 TIGRFAM TIGR01318 gltD_gamma_fam: glutamate synthase, small subunit 178 641 6.1E-228 T 29-03-2018 IPR006006 Glutamate synthase, NADH/NADPH, small subunit 2 GO:0006537|GO:0016639 MC49_RS19140 34cb9df5282d9c6fb6e53f3b221e6298 654 Pfam PF13450 NAD(P)-binding Rossmann-like domain 321 355 2.9E-7 T 29-03-2018 MC49_RS19140 34cb9df5282d9c6fb6e53f3b221e6298 654 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 87 98 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MC49_RS19140 34cb9df5282d9c6fb6e53f3b221e6298 654 Gene3D G3DSA:3.30.70.20 125 149 0.18 T 29-03-2018 MC49_RS19140 34cb9df5282d9c6fb6e53f3b221e6298 654 Gene3D G3DSA:3.50.50.60 320 409 1.5E-14 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS19140 34cb9df5282d9c6fb6e53f3b221e6298 654 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 451 629 2.9E-12 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS19140 34cb9df5282d9c6fb6e53f3b221e6298 654 Gene3D G3DSA:3.30.70.20 96 124 2.3E-10 T 29-03-2018 MC49_RS19140 34cb9df5282d9c6fb6e53f3b221e6298 654 PRINTS PR00419 Adrenodoxin reductase family signature 383 393 1.9E-35 T 29-03-2018 MC49_RS19140 34cb9df5282d9c6fb6e53f3b221e6298 654 PRINTS PR00419 Adrenodoxin reductase family signature 318 340 1.9E-35 T 29-03-2018 MC49_RS19140 34cb9df5282d9c6fb6e53f3b221e6298 654 PRINTS PR00419 Adrenodoxin reductase family signature 460 474 1.9E-35 T 29-03-2018 MC49_RS19140 34cb9df5282d9c6fb6e53f3b221e6298 654 PRINTS PR00419 Adrenodoxin reductase family signature 341 354 1.9E-35 T 29-03-2018 MC49_RS19140 34cb9df5282d9c6fb6e53f3b221e6298 654 PRINTS PR00419 Adrenodoxin reductase family signature 494 507 1.9E-35 T 29-03-2018 MC49_RS19140 34cb9df5282d9c6fb6e53f3b221e6298 654 SUPERFAMILY SSF51971 316 571 3.53E-62 T 29-03-2018 MC49_RS19140 34cb9df5282d9c6fb6e53f3b221e6298 654 SUPERFAMILY SSF54862 1 158 1.88E-41 T 29-03-2018 MC49_RS19140 34cb9df5282d9c6fb6e53f3b221e6298 654 SUPERFAMILY SSF54862 192 279 1.88E-41 T 29-03-2018 MC49_RS19140 34cb9df5282d9c6fb6e53f3b221e6298 654 Gene3D G3DSA:3.30.70.20 2 65 2.1E-10 T 29-03-2018 MC49_RS19140 34cb9df5282d9c6fb6e53f3b221e6298 654 Gene3D G3DSA:1.10.1060.10 163 319 2.9E-32 T 29-03-2018 MC49_RS19140 34cb9df5282d9c6fb6e53f3b221e6298 654 Gene3D G3DSA:3.50.50.60 410 483 1.7E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS19140 34cb9df5282d9c6fb6e53f3b221e6298 654 Gene3D G3DSA:3.50.50.60 484 571 6.7E-13 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS19140 34cb9df5282d9c6fb6e53f3b221e6298 654 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 193 303 6.1E-34 T 29-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 MC49_RS19140 34cb9df5282d9c6fb6e53f3b221e6298 654 Pfam PF13247 4Fe-4S dicluster domain 53 141 1.7E-11 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MC49_RS19140 34cb9df5282d9c6fb6e53f3b221e6298 654 Gene3D G3DSA:3.50.50.60 573 653 5.2E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS11840 bcd36afec733895fc34347e38bca10b6 302 Pfam PF01926 50S ribosome-binding GTPase 11 125 2.8E-23 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MC49_RS11840 bcd36afec733895fc34347e38bca10b6 302 SUPERFAMILY SSF54814 182 297 1.44E-41 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 MC49_RS11840 bcd36afec733895fc34347e38bca10b6 302 Gene3D G3DSA:3.40.50.300 3 55 4.9E-14 T 29-03-2018 MC49_RS11840 bcd36afec733895fc34347e38bca10b6 302 Pfam PF07650 KH domain 209 285 3.9E-18 T 29-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS11840 bcd36afec733895fc34347e38bca10b6 302 Gene3D G3DSA:3.30.300.20 186 300 3.4E-42 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta MC49_RS11840 bcd36afec733895fc34347e38bca10b6 302 SUPERFAMILY SSF52540 11 205 1.68E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS11840 bcd36afec733895fc34347e38bca10b6 302 TIGRFAM TIGR00436 era: GTP-binding protein Era 9 280 2.4E-113 T 29-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS11840 bcd36afec733895fc34347e38bca10b6 302 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 170 5.0E-39 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MC49_RS11840 bcd36afec733895fc34347e38bca10b6 302 Gene3D G3DSA:3.40.50.300 56 179 5.7E-15 T 29-03-2018 MC49_RS11840 bcd36afec733895fc34347e38bca10b6 302 Hamap MF_00367 GTPase Era [era]. 6 297 35.814 T 29-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS19170 ff8d213206cf54680c478c4af3ec8e02 82 Pfam PF01197 Ribosomal protein L31 1 78 1.1E-25 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS19170 ff8d213206cf54680c478c4af3ec8e02 82 PRINTS PR01249 Ribosomal protein L31 signature 2 19 3.6E-15 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS19170 ff8d213206cf54680c478c4af3ec8e02 82 PRINTS PR01249 Ribosomal protein L31 signature 44 59 3.6E-15 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS19170 ff8d213206cf54680c478c4af3ec8e02 82 PRINTS PR01249 Ribosomal protein L31 signature 59 77 3.6E-15 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS19170 ff8d213206cf54680c478c4af3ec8e02 82 ProSitePatterns PS01143 Ribosomal protein L31 signature. 48 69 - T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS19170 ff8d213206cf54680c478c4af3ec8e02 82 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 80 27.339 T 29-03-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS19170 ff8d213206cf54680c478c4af3ec8e02 82 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 79 3.2E-18 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS19170 ff8d213206cf54680c478c4af3ec8e02 82 SUPERFAMILY SSF143800 1 80 2.24E-22 T 29-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS15415 000ed2500daba8ca170c440ad7deb520 339 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 84 94 - T 29-03-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 MC49_RS15415 000ed2500daba8ca170c440ad7deb520 339 SMART SM00870 5 323 4.1E-138 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MC49_RS15415 000ed2500daba8ca170c440ad7deb520 339 PRINTS PR00139 Asparaginase/glutaminase family signature 83 101 6.4E-17 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MC49_RS15415 000ed2500daba8ca170c440ad7deb520 339 PRINTS PR00139 Asparaginase/glutaminase family signature 260 278 6.4E-17 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MC49_RS15415 000ed2500daba8ca170c440ad7deb520 339 PRINTS PR00139 Asparaginase/glutaminase family signature 6 17 6.4E-17 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MC49_RS15415 000ed2500daba8ca170c440ad7deb520 339 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 8 16 - T 29-03-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 MC49_RS15415 000ed2500daba8ca170c440ad7deb520 339 Gene3D G3DSA:3.40.50.40 210 337 1.1E-40 T 29-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 MC49_RS15415 000ed2500daba8ca170c440ad7deb520 339 PIRSF PIRSF500176 2 332 1.4E-110 T 29-03-2018 MC49_RS15415 000ed2500daba8ca170c440ad7deb520 339 SUPERFAMILY SSF53774 3 335 1.57E-111 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MC49_RS15415 000ed2500daba8ca170c440ad7deb520 339 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 3 335 4.1E-120 T 29-03-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 MC49_RS15415 000ed2500daba8ca170c440ad7deb520 339 PIRSF PIRSF001220 1 334 1.6E-94 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MC49_RS15415 000ed2500daba8ca170c440ad7deb520 339 Gene3D G3DSA:3.40.50.1170 1 208 2.2E-79 T 29-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 MC49_RS15415 000ed2500daba8ca170c440ad7deb520 339 Pfam PF00710 Asparaginase, N-terminal 6 188 7.1E-63 T 29-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 MC49_RS07020 cf8f08c1e284b9fe221452f3ab585c4f 563 SUPERFAMILY SSF52467 195 359 1.04E-57 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MC49_RS07020 cf8f08c1e284b9fe221452f3ab585c4f 563 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 428 447 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 MC49_RS07020 cf8f08c1e284b9fe221452f3ab585c4f 563 Gene3D G3DSA:3.40.50.970 6 198 5.5E-61 T 29-03-2018 MC49_RS07020 cf8f08c1e284b9fe221452f3ab585c4f 563 SUPERFAMILY SSF52518 365 562 8.67E-67 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MC49_RS07020 cf8f08c1e284b9fe221452f3ab585c4f 563 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 391 539 2.2E-48 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MC49_RS07020 cf8f08c1e284b9fe221452f3ab585c4f 563 Gene3D G3DSA:3.40.50.970 351 551 1.1E-50 T 29-03-2018 MC49_RS07020 cf8f08c1e284b9fe221452f3ab585c4f 563 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 13 562 6.0E-199 T 29-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 MC49_RS07020 cf8f08c1e284b9fe221452f3ab585c4f 563 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 13 181 1.9E-56 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MC49_RS07020 cf8f08c1e284b9fe221452f3ab585c4f 563 Gene3D G3DSA:3.40.50.1220 199 350 8.4E-51 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MC49_RS07020 cf8f08c1e284b9fe221452f3ab585c4f 563 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 201 335 5.0E-45 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MC49_RS07020 cf8f08c1e284b9fe221452f3ab585c4f 563 SUPERFAMILY SSF52518 7 189 1.09E-59 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MC49_RS11040 25ddc8d907d8c6cdf9a50a3e27ba432a 72 Gene3D G3DSA:2.40.50.140 1 72 3.1E-35 T 29-03-2018 MC49_RS11040 25ddc8d907d8c6cdf9a50a3e27ba432a 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 1.3E-38 T 29-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 MC49_RS11040 25ddc8d907d8c6cdf9a50a3e27ba432a 72 SUPERFAMILY SSF50249 1 70 1.18E-28 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS11040 25ddc8d907d8c6cdf9a50a3e27ba432a 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 27.17 T 29-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 MC49_RS11040 25ddc8d907d8c6cdf9a50a3e27ba432a 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 3.1E-27 T 29-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 MC49_RS11040 25ddc8d907d8c6cdf9a50a3e27ba432a 72 SMART SM00316 4 72 4.3E-7 T 29-03-2018 IPR022967 RNA-binding domain, S1 MC49_RS13915 24d5b1d603205a69ea715fca9294ca07 420 SUPERFAMILY SSF69075 317 418 2.48E-27 T 29-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MC49_RS13915 24d5b1d603205a69ea715fca9294ca07 420 Gene3D G3DSA:3.40.50.720 161 313 3.3E-22 T 29-03-2018 MC49_RS13915 24d5b1d603205a69ea715fca9294ca07 420 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 4 417 1.4E-156 T 29-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MC49_RS13915 24d5b1d603205a69ea715fca9294ca07 420 PIRSF PIRSF000445 1 420 3.8E-156 T 29-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MC49_RS13915 24d5b1d603205a69ea715fca9294ca07 420 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 172 306 3.5E-48 T 29-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase MC49_RS13915 24d5b1d603205a69ea715fca9294ca07 420 SUPERFAMILY SSF51735 162 315 1.44E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS13915 24d5b1d603205a69ea715fca9294ca07 420 Gene3D G3DSA:1.10.1200.70 332 418 7.8E-24 T 29-03-2018 MC49_RS13915 24d5b1d603205a69ea715fca9294ca07 420 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 156 7.4E-50 T 29-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MC49_RS13915 24d5b1d603205a69ea715fca9294ca07 420 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 418 30.835 T 29-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MC49_RS13915 24d5b1d603205a69ea715fca9294ca07 420 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 29-03-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MC49_RS13915 24d5b1d603205a69ea715fca9294ca07 420 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 320 414 7.3E-24 T 29-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MC49_RS13915 24d5b1d603205a69ea715fca9294ca07 420 SUPERFAMILY SSF69742 1 158 3.01E-48 T 29-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MC49_RS18255 91061e63da335d6c9e002b3f1c6535fb 83 Gene3D G3DSA:3.30.910.10 1 76 4.9E-23 T 29-03-2018 IPR010391 DNA damage-inducible protein DinI-like MC49_RS18255 91061e63da335d6c9e002b3f1c6535fb 83 Pfam PF06183 DinI-like family 14 76 8.1E-21 T 29-03-2018 IPR010391 DNA damage-inducible protein DinI-like MC49_RS18255 91061e63da335d6c9e002b3f1c6535fb 83 SUPERFAMILY SSF54857 1 76 1.57E-17 T 29-03-2018 IPR010391 DNA damage-inducible protein DinI-like MC49_RS04155 8c9241ef8aac57bebd9934a8ead7c309 201 Gene3D G3DSA:3.40.1370.10 141 199 5.1E-11 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 MC49_RS04155 8c9241ef8aac57bebd9934a8ead7c309 201 Gene3D G3DSA:3.40.1370.10 3 140 2.4E-48 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 MC49_RS04155 8c9241ef8aac57bebd9934a8ead7c309 201 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 6 201 33.357 T 29-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS04155 8c9241ef8aac57bebd9934a8ead7c309 201 SUPERFAMILY SSF52166 10 200 2.88E-71 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 MC49_RS04155 8c9241ef8aac57bebd9934a8ead7c309 201 Pfam PF00573 Ribosomal protein L4/L1 family 13 198 1.5E-62 T 29-03-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 MC49_RS04155 8c9241ef8aac57bebd9934a8ead7c309 201 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 13 198 3.1E-73 T 29-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS10460 e7e52908b504e52595d49d450a6406c5 164 TIGRFAM TIGR02802 Pal_lipo: peptidoglycan-associated lipoprotein 62 164 9.2E-46 T 29-03-2018 IPR014169 Peptidoglycan-associated lipoprotein GO:0009279 MC49_RS10460 e7e52908b504e52595d49d450a6406c5 164 PRINTS PR01021 OMPA domain signature 94 109 7.6E-19 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MC49_RS10460 e7e52908b504e52595d49d450a6406c5 164 PRINTS PR01021 OMPA domain signature 109 125 7.6E-19 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MC49_RS10460 e7e52908b504e52595d49d450a6406c5 164 PRINTS PR01021 OMPA domain signature 64 86 7.6E-19 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MC49_RS10460 e7e52908b504e52595d49d450a6406c5 164 SUPERFAMILY SSF103088 61 164 1.96E-35 T 29-03-2018 IPR006665 OmpA-like domain MC49_RS10460 e7e52908b504e52595d49d450a6406c5 164 Pfam PF00691 OmpA family 63 158 2.5E-22 T 29-03-2018 IPR006665 OmpA-like domain MC49_RS10460 e7e52908b504e52595d49d450a6406c5 164 ProSitePatterns PS01068 OmpA-like domain. 96 140 - T 29-03-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 MC49_RS10460 e7e52908b504e52595d49d450a6406c5 164 Gene3D G3DSA:3.30.1330.60 34 164 1.8E-35 T 29-03-2018 IPR006665 OmpA-like domain MC49_RS03695 d501c3cef1fe810ddb5e222cef4a5ce1 316 Gene3D G3DSA:3.30.460.20 1 125 4.0E-10 T 29-03-2018 MC49_RS03695 d501c3cef1fe810ddb5e222cef4a5ce1 316 Gene3D G3DSA:1.20.58.340 131 248 5.9E-8 T 29-03-2018 MC49_RS03695 d501c3cef1fe810ddb5e222cef4a5ce1 316 SUPERFAMILY SSF144083 251 314 1.1E-20 T 29-03-2018 MC49_RS03695 d501c3cef1fe810ddb5e222cef4a5ce1 316 Gene3D G3DSA:1.20.58.340 249 316 2.1E-21 T 29-03-2018 MC49_RS03695 d501c3cef1fe810ddb5e222cef4a5ce1 316 SUPERFAMILY SSF143865 1 255 7.19E-36 T 29-03-2018 MC49_RS03695 d501c3cef1fe810ddb5e222cef4a5ce1 316 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 9 316 5.1E-102 T 29-03-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 MC49_RS03695 d501c3cef1fe810ddb5e222cef4a5ce1 316 Pfam PF01544 CorA-like Mg2+ transporter protein 25 312 9.4E-54 T 29-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 MC49_RS11205 6c9d4d42a9648c491a8c37e9f0763cf3 577 Pfam PF03734 L,D-transpeptidase catalytic domain 334 501 5.7E-28 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 MC49_RS11205 6c9d4d42a9648c491a8c37e9f0763cf3 577 Gene3D G3DSA:2.40.440.10 333 507 1.4E-22 T 29-03-2018 MC49_RS11205 6c9d4d42a9648c491a8c37e9f0763cf3 577 Gene3D G3DSA:1.10.101.10 237 310 1.0E-17 T 29-03-2018 IPR002477 Peptidoglycan binding-like MC49_RS11205 6c9d4d42a9648c491a8c37e9f0763cf3 577 Pfam PF01471 Putative peptidoglycan binding domain 248 307 1.0E-9 T 29-03-2018 IPR002477 Peptidoglycan binding-like MC49_RS11205 6c9d4d42a9648c491a8c37e9f0763cf3 577 SUPERFAMILY SSF141523 444 493 1.7E-18 T 29-03-2018 MC49_RS11205 6c9d4d42a9648c491a8c37e9f0763cf3 577 SUPERFAMILY SSF141523 332 387 1.7E-18 T 29-03-2018 MC49_RS11205 6c9d4d42a9648c491a8c37e9f0763cf3 577 SUPERFAMILY SSF47090 233 315 5.41E-14 T 29-03-2018 IPR002477 Peptidoglycan binding-like MC49_RS18330 3858fa5b2449b8d3b4d4d0e32cc9f77d 102 Gene3D G3DSA:3.30.70.100 1 94 5.6E-19 T 29-03-2018 MC49_RS18330 3858fa5b2449b8d3b4d4d0e32cc9f77d 102 SUPERFAMILY SSF54909 1 100 5.78E-26 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel MC49_RS18330 3858fa5b2449b8d3b4d4d0e32cc9f77d 102 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 76 6.5E-13 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain MC49_RS13530 4cd78e6d0656412fa48dfb0c2a0421ed 268 SUPERFAMILY SSF56281 14 247 1.83E-29 T 29-03-2018 IPR001279 Metallo-beta-lactamase MC49_RS13530 4cd78e6d0656412fa48dfb0c2a0421ed 268 Pfam PF00753 Metallo-beta-lactamase superfamily 21 80 2.9E-14 T 29-03-2018 IPR001279 Metallo-beta-lactamase MC49_RS13530 4cd78e6d0656412fa48dfb0c2a0421ed 268 SMART SM00849 21 189 0.0014 T 29-03-2018 IPR001279 Metallo-beta-lactamase MC49_RS13530 4cd78e6d0656412fa48dfb0c2a0421ed 268 ProSitePatterns PS00141 Eukaryotic and viral aspartyl proteases active site. 34 45 - T 29-03-2018 IPR001969 Aspartic peptidase, active site GO:0004190|GO:0006508 MC49_RS13530 4cd78e6d0656412fa48dfb0c2a0421ed 268 Gene3D G3DSA:3.60.15.10 5 261 6.7E-21 T 29-03-2018 IPR001279 Metallo-beta-lactamase MC49_RS07455 f388f8de8b20fd52f81eae30b4ac846f 462 Hamap MF_01498 DNA repair protein RadA [radA]. 22 459 43.253 T 29-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 MC49_RS07455 f388f8de8b20fd52f81eae30b4ac846f 462 TIGRFAM TIGR00416 sms: DNA repair protein RadA 2 455 2.1E-235 T 29-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 MC49_RS07455 f388f8de8b20fd52f81eae30b4ac846f 462 Gene3D G3DSA:3.30.230.10 289 458 3.5E-31 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MC49_RS07455 f388f8de8b20fd52f81eae30b4ac846f 462 Pfam PF13541 Subunit ChlI of Mg-chelatase 349 434 4.2E-9 T 29-03-2018 MC49_RS07455 f388f8de8b20fd52f81eae30b4ac846f 462 SMART SM00382 95 248 4.2E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS07455 f388f8de8b20fd52f81eae30b4ac846f 462 SUPERFAMILY SSF52540 72 291 6.11E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS07455 f388f8de8b20fd52f81eae30b4ac846f 462 Gene3D G3DSA:3.40.50.300 77 287 1.5E-40 T 29-03-2018 MC49_RS07455 f388f8de8b20fd52f81eae30b4ac846f 462 PRINTS PR01874 DNA repair protein radA signature 252 278 1.0E-93 T 29-03-2018 MC49_RS07455 f388f8de8b20fd52f81eae30b4ac846f 462 PRINTS PR01874 DNA repair protein radA signature 87 115 1.0E-93 T 29-03-2018 MC49_RS07455 f388f8de8b20fd52f81eae30b4ac846f 462 PRINTS PR01874 DNA repair protein radA signature 326 349 1.0E-93 T 29-03-2018 MC49_RS07455 f388f8de8b20fd52f81eae30b4ac846f 462 PRINTS PR01874 DNA repair protein radA signature 178 202 1.0E-93 T 29-03-2018 MC49_RS07455 f388f8de8b20fd52f81eae30b4ac846f 462 PRINTS PR01874 DNA repair protein radA signature 11 35 1.0E-93 T 29-03-2018 MC49_RS07455 f388f8de8b20fd52f81eae30b4ac846f 462 PRINTS PR01874 DNA repair protein radA signature 128 145 1.0E-93 T 29-03-2018 MC49_RS07455 f388f8de8b20fd52f81eae30b4ac846f 462 PRINTS PR01874 DNA repair protein radA signature 217 245 1.0E-93 T 29-03-2018 MC49_RS07455 f388f8de8b20fd52f81eae30b4ac846f 462 SUPERFAMILY SSF54211 307 458 1.06E-41 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MC49_RS07455 f388f8de8b20fd52f81eae30b4ac846f 462 SUPERFAMILY SSF54211 259 273 1.06E-41 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MC49_RS07455 f388f8de8b20fd52f81eae30b4ac846f 462 Pfam PF13481 AAA domain 89 226 3.1E-15 T 29-03-2018 MC49_RS11170 d90816837ed50e41ff938ff0ff056f2f 265 Pfam PF02698 DUF218 domain 89 249 1.2E-22 T 29-03-2018 IPR003848 Domain of unknown function DUF218 MC49_RS11170 d90816837ed50e41ff938ff0ff056f2f 265 Gene3D G3DSA:3.40.50.620 78 222 4.7E-24 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS04455 00491f84c422c1923a9fa32490435a24 392 SUPERFAMILY SSF53187 19 202 1.71E-62 T 29-03-2018 MC49_RS04455 00491f84c422c1923a9fa32490435a24 392 SUPERFAMILY SSF53187 301 391 1.71E-62 T 29-03-2018 MC49_RS04455 00491f84c422c1923a9fa32490435a24 392 Pfam PF07687 Peptidase dimerisation domain 191 283 1.6E-11 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain MC49_RS04455 00491f84c422c1923a9fa32490435a24 392 Pfam PF01546 Peptidase family M20/M25/M40 78 389 2.5E-20 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 MC49_RS04455 00491f84c422c1923a9fa32490435a24 392 Gene3D G3DSA:3.40.630.10 1 250 1.7E-35 T 29-03-2018 MC49_RS04455 00491f84c422c1923a9fa32490435a24 392 Gene3D G3DSA:3.40.630.10 254 392 9.3E-14 T 29-03-2018 MC49_RS04455 00491f84c422c1923a9fa32490435a24 392 SUPERFAMILY SSF55031 191 283 1.18E-20 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain MC49_RS04455 00491f84c422c1923a9fa32490435a24 392 PIRSF PIRSF005962 3 392 8.6E-107 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 MC49_RS04455 00491f84c422c1923a9fa32490435a24 392 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 21 382 4.7E-82 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 MC49_RS06230 5338818d5ccb0a8781a5ac1955703404 930 SUPERFAMILY SSF47807 171 291 1.23E-32 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 MC49_RS06230 5338818d5ccb0a8781a5ac1955703404 930 Gene3D G3DSA:1.20.1060.10 545 658 7.6E-36 T 29-03-2018 MC49_RS06230 5338818d5ccb0a8781a5ac1955703404 930 SMART SM00279 173 208 4.8E-14 T 29-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 MC49_RS06230 5338818d5ccb0a8781a5ac1955703404 930 SUPERFAMILY SSF88723 7 170 1.57E-55 T 29-03-2018 IPR029060 PIN domain-like MC49_RS06230 5338818d5ccb0a8781a5ac1955703404 930 SMART SM00482 688 894 2.7E-123 T 29-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS06230 5338818d5ccb0a8781a5ac1955703404 930 SMART SM00475 7 268 7.9E-143 T 29-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 MC49_RS06230 5338818d5ccb0a8781a5ac1955703404 930 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 9 170 1.8E-55 T 29-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 MC49_RS06230 5338818d5ccb0a8781a5ac1955703404 930 Pfam PF00476 DNA polymerase family A 553 928 2.6E-161 T 29-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS06230 5338818d5ccb0a8781a5ac1955703404 930 PRINTS PR00868 DNA-polymerase family A (pol I) signature 847 863 2.6E-78 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS06230 5338818d5ccb0a8781a5ac1955703404 930 PRINTS PR00868 DNA-polymerase family A (pol I) signature 680 695 2.6E-78 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS06230 5338818d5ccb0a8781a5ac1955703404 930 PRINTS PR00868 DNA-polymerase family A (pol I) signature 756 781 2.6E-78 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS06230 5338818d5ccb0a8781a5ac1955703404 930 PRINTS PR00868 DNA-polymerase family A (pol I) signature 732 745 2.6E-78 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS06230 5338818d5ccb0a8781a5ac1955703404 930 PRINTS PR00868 DNA-polymerase family A (pol I) signature 815 826 2.6E-78 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS06230 5338818d5ccb0a8781a5ac1955703404 930 PRINTS PR00868 DNA-polymerase family A (pol I) signature 657 679 2.6E-78 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS06230 5338818d5ccb0a8781a5ac1955703404 930 PRINTS PR00868 DNA-polymerase family A (pol I) signature 793 804 2.6E-78 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS06230 5338818d5ccb0a8781a5ac1955703404 930 PRINTS PR00868 DNA-polymerase family A (pol I) signature 702 725 2.6E-78 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS06230 5338818d5ccb0a8781a5ac1955703404 930 PRINTS PR00868 DNA-polymerase family A (pol I) signature 877 890 2.6E-78 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS06230 5338818d5ccb0a8781a5ac1955703404 930 SMART SM00474 332 519 1.6E-44 T 29-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 MC49_RS06230 5338818d5ccb0a8781a5ac1955703404 930 Gene3D G3DSA:3.40.50.1010 7 183 2.2E-68 T 29-03-2018 IPR029060 PIN domain-like MC49_RS06230 5338818d5ccb0a8781a5ac1955703404 930 TIGRFAM TIGR00593 pola: DNA polymerase I 9 930 1.3E-298 T 29-03-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS06230 5338818d5ccb0a8781a5ac1955703404 930 Gene3D G3DSA:3.30.420.10 323 544 1.9E-52 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MC49_RS06230 5338818d5ccb0a8781a5ac1955703404 930 SUPERFAMILY SSF53098 329 519 1.9E-55 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MC49_RS06230 5338818d5ccb0a8781a5ac1955703404 930 Pfam PF01612 3'-5' exonuclease 332 519 1.1E-39 T 29-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 MC49_RS06230 5338818d5ccb0a8781a5ac1955703404 930 Gene3D G3DSA:1.10.150.20 184 269 5.5E-25 T 29-03-2018 MC49_RS06230 5338818d5ccb0a8781a5ac1955703404 930 SUPERFAMILY SSF56672 524 930 1.45E-164 T 29-03-2018 MC49_RS06230 5338818d5ccb0a8781a5ac1955703404 930 ProSitePatterns PS00447 DNA polymerase family A signature. 756 775 - T 29-03-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS06230 5338818d5ccb0a8781a5ac1955703404 930 Gene3D G3DSA:3.30.70.370 756 930 2.7E-54 T 29-03-2018 MC49_RS06230 5338818d5ccb0a8781a5ac1955703404 930 Gene3D G3DSA:3.30.70.370 659 755 8.7E-19 T 29-03-2018 MC49_RS06230 5338818d5ccb0a8781a5ac1955703404 930 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 171 271 2.3E-30 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 MC49_RS11065 39cefdf2f1ff75744fac0298c59f9a05 164 ProSitePatterns PS00519 AsnC-type HTH domain signature. 30 56 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site MC49_RS11065 39cefdf2f1ff75744fac0298c59f9a05 164 Gene3D G3DSA:1.10.10.10 13 64 4.2E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS11065 39cefdf2f1ff75744fac0298c59f9a05 164 Pfam PF13412 Winged helix-turn-helix DNA-binding 12 59 2.2E-21 T 29-03-2018 MC49_RS11065 39cefdf2f1ff75744fac0298c59f9a05 164 SUPERFAMILY SSF54909 74 157 4.16E-22 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel MC49_RS11065 39cefdf2f1ff75744fac0298c59f9a05 164 SMART SM00344 12 121 2.3E-55 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MC49_RS11065 39cefdf2f1ff75744fac0298c59f9a05 164 SUPERFAMILY SSF46785 12 70 4.12E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS11065 39cefdf2f1ff75744fac0298c59f9a05 164 Pfam PF01037 Lrp/AsnC ligand binding domain 78 152 1.1E-24 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MC49_RS11065 39cefdf2f1ff75744fac0298c59f9a05 164 Gene3D G3DSA:3.30.70.920 65 158 1.9E-27 T 29-03-2018 MC49_RS11065 39cefdf2f1ff75744fac0298c59f9a05 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 12 28 6.2E-23 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MC49_RS11065 39cefdf2f1ff75744fac0298c59f9a05 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 39 6.2E-23 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MC49_RS11065 39cefdf2f1ff75744fac0298c59f9a05 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 39 58 6.2E-23 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MC49_RS04130 d8ad55129a721f9a0be017b39a34c669 233 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 39.308 T 29-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 MC49_RS04130 d8ad55129a721f9a0be017b39a34c669 233 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 29-03-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04130 d8ad55129a721f9a0be017b39a34c669 233 SUPERFAMILY SSF54814 2 106 1.47E-37 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 MC49_RS04130 d8ad55129a721f9a0be017b39a34c669 233 Pfam PF07650 KH domain 38 111 2.6E-19 T 29-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04130 d8ad55129a721f9a0be017b39a34c669 233 Gene3D G3DSA:3.30.300.20 17 107 1.2E-28 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta MC49_RS04130 d8ad55129a721f9a0be017b39a34c669 233 Gene3D G3DSA:3.30.1140.32 108 207 4.5E-40 T 29-03-2018 MC49_RS04130 d8ad55129a721f9a0be017b39a34c669 233 SUPERFAMILY SSF54821 108 206 1.1E-40 T 29-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04130 d8ad55129a721f9a0be017b39a34c669 233 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 209 9.4E-101 T 29-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 MC49_RS04130 d8ad55129a721f9a0be017b39a34c669 233 Pfam PF00189 Ribosomal protein S3, C-terminal domain 120 202 3.4E-41 T 29-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04130 d8ad55129a721f9a0be017b39a34c669 233 SMART SM00322 60 125 1.7E-7 T 29-03-2018 IPR004087 K Homology domain GO:0003676 MC49_RS10605 3e5f21ae087ccdd03867d320994b1dda 180 Pfam PF13302 Acetyltransferase (GNAT) domain 15 160 4.3E-25 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MC49_RS10605 3e5f21ae087ccdd03867d320994b1dda 180 Gene3D G3DSA:3.40.630.30 2 180 3.5E-23 T 29-03-2018 MC49_RS10605 3e5f21ae087ccdd03867d320994b1dda 180 SUPERFAMILY SSF55729 7 166 1.03E-35 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS03345 c588d894d5421c9699d373dcbb685cf0 635 Pfam PF03880 DbpA RNA binding domain 494 563 5.8E-21 T 29-03-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain MC49_RS03345 c588d894d5421c9699d373dcbb685cf0 635 SUPERFAMILY SSF52540 5 210 1.58E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS03345 c588d894d5421c9699d373dcbb685cf0 635 SMART SM00487 26 224 7.6E-65 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MC49_RS03345 c588d894d5421c9699d373dcbb685cf0 635 Gene3D G3DSA:3.40.50.300 10 222 6.3E-60 T 29-03-2018 MC49_RS03345 c588d894d5421c9699d373dcbb685cf0 635 Pfam PF00271 Helicase conserved C-terminal domain 233 341 5.1E-29 T 29-03-2018 IPR001650 Helicase, C-terminal MC49_RS03345 c588d894d5421c9699d373dcbb685cf0 635 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 155 163 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site MC49_RS03345 c588d894d5421c9699d373dcbb685cf0 635 SMART SM00490 260 341 5.1E-32 T 29-03-2018 IPR001650 Helicase, C-terminal MC49_RS03345 c588d894d5421c9699d373dcbb685cf0 635 SUPERFAMILY SSF52540 148 355 5.7E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS03345 c588d894d5421c9699d373dcbb685cf0 635 Pfam PF00270 DEAD/DEAH box helicase 32 196 3.3E-50 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MC49_RS03345 c588d894d5421c9699d373dcbb685cf0 635 Gene3D G3DSA:3.40.50.300 223 409 1.6E-42 T 29-03-2018 MC49_RS03345 c588d894d5421c9699d373dcbb685cf0 635 Hamap MF_00964 ATP-dependent RNA helicase DeaD [deaD]. 2 565 46.659 T 29-03-2018 IPR028618 ATP-dependent RNA helicase DeaD GO:0000027|GO:0004004|GO:0070417 MC49_RS03895 129874aadd3d4bffa7ebe933da79dcde 308 ProSitePatterns PS00770 Aminotransferases class-IV signature. 193 222 - T 29-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 MC49_RS03895 129874aadd3d4bffa7ebe933da79dcde 308 SUPERFAMILY SSF56752 6 306 7.33E-105 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 MC49_RS03895 129874aadd3d4bffa7ebe933da79dcde 308 Gene3D G3DSA:3.20.10.10 142 302 9.1E-48 T 29-03-2018 MC49_RS03895 129874aadd3d4bffa7ebe933da79dcde 308 Gene3D G3DSA:3.30.470.10 1 141 2.9E-42 T 29-03-2018 MC49_RS03895 129874aadd3d4bffa7ebe933da79dcde 308 Pfam PF01063 Amino-transferase class IV 35 267 6.2E-50 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 MC49_RS03895 129874aadd3d4bffa7ebe933da79dcde 308 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 9 306 7.3E-143 T 29-03-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 MC49_RS04250 c988f42dc1d596df20e5bd855f9fa42b 288 Gene3D G3DSA:3.40.50.1860 22 141 2.4E-27 T 29-03-2018 MC49_RS04250 c988f42dc1d596df20e5bd855f9fa42b 288 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 91 99 - T 29-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MC49_RS04250 c988f42dc1d596df20e5bd855f9fa42b 288 Hamap MF_00258 Glutamate racemase [murI]. 24 277 32.742 T 29-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MC49_RS04250 c988f42dc1d596df20e5bd855f9fa42b 288 TIGRFAM TIGR00067 glut_race: glutamate racemase 26 270 2.8E-76 T 29-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MC49_RS04250 c988f42dc1d596df20e5bd855f9fa42b 288 SUPERFAMILY SSF53681 26 127 1.05E-30 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MC49_RS04250 c988f42dc1d596df20e5bd855f9fa42b 288 SUPERFAMILY SSF53681 129 282 1.94E-33 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MC49_RS04250 c988f42dc1d596df20e5bd855f9fa42b 288 Pfam PF01177 Asp/Glu/Hydantoin racemase 29 236 1.4E-27 T 29-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MC49_RS04250 c988f42dc1d596df20e5bd855f9fa42b 288 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 202 212 - T 29-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MC49_RS04250 c988f42dc1d596df20e5bd855f9fa42b 288 Gene3D G3DSA:3.40.50.1860 142 286 5.0E-27 T 29-03-2018 MC49_RS07980 dec455d64e1e0921f72595c67af8d6ba 283 SUPERFAMILY SSF55620 187 270 6.23E-10 T 29-03-2018 MC49_RS07980 dec455d64e1e0921f72595c67af8d6ba 283 Gene3D G3DSA:3.30.1130.10 21 136 1.1E-36 T 29-03-2018 MC49_RS07980 dec455d64e1e0921f72595c67af8d6ba 283 Pfam PF14489 QueF-like protein 197 271 4.4E-26 T 29-03-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 MC49_RS07980 dec455d64e1e0921f72595c67af8d6ba 283 PIRSF PIRSF004750 6 283 1.8E-121 T 29-03-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 MC49_RS07980 dec455d64e1e0921f72595c67af8d6ba 283 Gene3D G3DSA:3.30.1130.10 144 283 5.5E-47 T 29-03-2018 MC49_RS07980 dec455d64e1e0921f72595c67af8d6ba 283 Pfam PF14819 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term 21 131 1.7E-44 T 29-03-2018 IPR029139 NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 MC49_RS07980 dec455d64e1e0921f72595c67af8d6ba 283 TIGRFAM TIGR03138 QueF: queuine synthase 11 283 4.8E-121 T 29-03-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 MC49_RS07980 dec455d64e1e0921f72595c67af8d6ba 283 Hamap MF_00817 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 283 150.555 T 29-03-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 MC49_RS01030 e0f16e9c866c2b541e3a207a8d020093 80 Pfam PF10038 Protein of unknown function (DUF2274) 4 68 8.7E-26 T 29-03-2018 IPR018733 Protein of unknown function DUF2274 MC49_RS00505 4a40107f795faf6033847d3291f93034 312 Pfam PF01145 SPFH domain / Band 7 family 26 195 2.5E-35 T 29-03-2018 IPR001107 Band 7 domain MC49_RS00505 4a40107f795faf6033847d3291f93034 312 ProSitePatterns PS01270 Band 7 protein family signature. 136 164 - T 29-03-2018 IPR018080 Band 7/stomatin-like, conserved site MC49_RS00505 4a40107f795faf6033847d3291f93034 312 SUPERFAMILY SSF117892 53 187 3.66E-42 T 29-03-2018 IPR001107 Band 7 domain MC49_RS00505 4a40107f795faf6033847d3291f93034 312 PRINTS PR00721 Stomatin signature 156 174 8.0E-28 T 29-03-2018 IPR001972 Stomatin family GO:0016020 MC49_RS00505 4a40107f795faf6033847d3291f93034 312 PRINTS PR00721 Stomatin signature 175 196 8.0E-28 T 29-03-2018 IPR001972 Stomatin family GO:0016020 MC49_RS00505 4a40107f795faf6033847d3291f93034 312 PRINTS PR00721 Stomatin signature 77 98 8.0E-28 T 29-03-2018 IPR001972 Stomatin family GO:0016020 MC49_RS00505 4a40107f795faf6033847d3291f93034 312 PRINTS PR00721 Stomatin signature 132 155 8.0E-28 T 29-03-2018 IPR001972 Stomatin family GO:0016020 MC49_RS00505 4a40107f795faf6033847d3291f93034 312 PRINTS PR00721 Stomatin signature 112 129 8.0E-28 T 29-03-2018 IPR001972 Stomatin family GO:0016020 MC49_RS00505 4a40107f795faf6033847d3291f93034 312 SMART SM00244 22 180 3.9E-61 T 29-03-2018 IPR001107 Band 7 domain MC49_RS12510 f9e6605a25912c87fb6ec4ebf0ebf3ae 218 TIGRFAM TIGR03170 flgA_cterm: flagella basal body P-ring formation protein FlgA 83 216 8.9E-35 T 29-03-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal MC49_RS12510 f9e6605a25912c87fb6ec4ebf0ebf3ae 218 Pfam PF13144 Chaperone for flagella basal body P-ring formation 27 216 1.6E-37 T 29-03-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal MC49_RS12510 f9e6605a25912c87fb6ec4ebf0ebf3ae 218 Gene3D G3DSA:3.90.1210.10 92 159 2.3E-8 T 29-03-2018 MC49_RS12510 f9e6605a25912c87fb6ec4ebf0ebf3ae 218 SMART SM00858 94 156 0.0013 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 MC49_RS08265 f1525fee28edb5eedd78b29f01c0a0ba 853 Pfam PF05188 MutS domain II 131 256 3.1E-30 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 MC49_RS08265 f1525fee28edb5eedd78b29f01c0a0ba 853 Gene3D G3DSA:3.30.420.110 135 265 2.1E-29 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 MC49_RS08265 f1525fee28edb5eedd78b29f01c0a0ba 853 SUPERFAMILY SSF53150 117 269 5.62E-43 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 MC49_RS08265 f1525fee28edb5eedd78b29f01c0a0ba 853 Pfam PF05190 MutS family domain IV 428 518 2.4E-29 T 29-03-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 MC49_RS08265 f1525fee28edb5eedd78b29f01c0a0ba 853 Gene3D G3DSA:1.10.1420.10 408 535 3.0E-31 T 29-03-2018 MC49_RS08265 f1525fee28edb5eedd78b29f01c0a0ba 853 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 10 850 0.0 T 29-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 MC49_RS08265 f1525fee28edb5eedd78b29f01c0a0ba 853 Gene3D G3DSA:1.10.1420.10 266 407 1.2E-37 T 29-03-2018 MC49_RS08265 f1525fee28edb5eedd78b29f01c0a0ba 853 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 688 704 - T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 MC49_RS08265 f1525fee28edb5eedd78b29f01c0a0ba 853 SUPERFAMILY SSF55271 5 118 1.22E-42 T 29-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 MC49_RS08265 f1525fee28edb5eedd78b29f01c0a0ba 853 Gene3D G3DSA:3.40.50.300 567 822 7.7E-40 T 29-03-2018 MC49_RS08265 f1525fee28edb5eedd78b29f01c0a0ba 853 PIRSF PIRSF037677 2 823 2.0E-157 T 29-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 MC49_RS08265 f1525fee28edb5eedd78b29f01c0a0ba 853 SUPERFAMILY SSF52540 567 798 9.67E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS08265 f1525fee28edb5eedd78b29f01c0a0ba 853 SMART SM00534 607 794 8.9E-123 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 MC49_RS08265 f1525fee28edb5eedd78b29f01c0a0ba 853 Pfam PF01624 MutS domain I 11 122 5.2E-42 T 29-03-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 MC49_RS08265 f1525fee28edb5eedd78b29f01c0a0ba 853 SUPERFAMILY SSF48334 270 566 1.57E-90 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 MC49_RS08265 f1525fee28edb5eedd78b29f01c0a0ba 853 Pfam PF05192 MutS domain III 272 559 2.0E-39 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 MC49_RS08265 f1525fee28edb5eedd78b29f01c0a0ba 853 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 10 845 25.326 T 29-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 MC49_RS08265 f1525fee28edb5eedd78b29f01c0a0ba 853 Gene3D G3DSA:3.40.1170.10 1 134 3.2E-47 T 29-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 MC49_RS08265 f1525fee28edb5eedd78b29f01c0a0ba 853 SMART SM00533 286 591 8.3E-105 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 MC49_RS08265 f1525fee28edb5eedd78b29f01c0a0ba 853 Pfam PF00488 MutS domain V 610 797 1.7E-87 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 MC49_RS15210 2d74058f4f7ca3d41f53886166f7fb47 448 Gene3D G3DSA:3.30.565.10 296 448 9.1E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS15210 2d74058f4f7ca3d41f53886166f7fb47 448 Pfam PF00512 His Kinase A (phospho-acceptor) domain 237 300 3.6E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS15210 2d74058f4f7ca3d41f53886166f7fb47 448 SUPERFAMILY SSF55874 290 447 2.75E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS15210 2d74058f4f7ca3d41f53886166f7fb47 448 Gene3D G3DSA:1.20.5.1040 129 182 5.7E-11 T 29-03-2018 MC49_RS15210 2d74058f4f7ca3d41f53886166f7fb47 448 Gene3D G3DSA:1.20.5.1040 4 57 1.6E-11 T 29-03-2018 MC49_RS15210 2d74058f4f7ca3d41f53886166f7fb47 448 SMART SM00388 235 301 3.7E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS15210 2d74058f4f7ca3d41f53886166f7fb47 448 Gene3D G3DSA:1.10.287.130 226 295 7.0E-11 T 29-03-2018 MC49_RS15210 2d74058f4f7ca3d41f53886166f7fb47 448 SUPERFAMILY SSF47384 218 301 7.06E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS15210 2d74058f4f7ca3d41f53886166f7fb47 448 SMART SM00387 347 438 2.2E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS15210 2d74058f4f7ca3d41f53886166f7fb47 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 380 394 3.4E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS15210 2d74058f4f7ca3d41f53886166f7fb47 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 430 3.4E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS15210 2d74058f4f7ca3d41f53886166f7fb47 448 Pfam PF08521 Two-component sensor kinase N-terminal 19 154 2.1E-5 T 29-03-2018 IPR013727 Two-component sensor kinase, N-terminal MC49_RS15210 2d74058f4f7ca3d41f53886166f7fb47 448 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 351 442 5.1E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS11850 f2cfd1712fedd1ed6b3554f00a76ec51 243 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 243 131.043 T 29-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 MC49_RS11850 f2cfd1712fedd1ed6b3554f00a76ec51 243 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 6 237 2.9E-105 T 29-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 MC49_RS11850 f2cfd1712fedd1ed6b3554f00a76ec51 243 SUPERFAMILY SSF63892 4 242 3.79E-101 T 29-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 MC49_RS11850 f2cfd1712fedd1ed6b3554f00a76ec51 243 Gene3D G3DSA:3.20.20.70 4 238 4.7E-106 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS11850 f2cfd1712fedd1ed6b3554f00a76ec51 243 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 6 239 1.4E-103 T 29-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 MC49_RS07590 b99029eb97294fa43a59752017eba440 309 Gene3D G3DSA:1.10.10.10 1 88 1.7E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS07590 b99029eb97294fa43a59752017eba440 309 SUPERFAMILY SSF46785 2 86 1.86E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS07590 b99029eb97294fa43a59752017eba440 309 SUPERFAMILY SSF53850 92 289 1.54E-27 T 29-03-2018 MC49_RS07590 b99029eb97294fa43a59752017eba440 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 5.4E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS07590 b99029eb97294fa43a59752017eba440 309 Pfam PF03466 LysR substrate binding domain 98 287 1.2E-13 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS07590 b99029eb97294fa43a59752017eba440 309 Gene3D G3DSA:3.40.190.10 94 222 4.6E-8 T 29-03-2018 MC49_RS02995 dace4ba185a4b78ca38ef754e3c36e45 441 SUPERFAMILY SSF53187 11 223 1.03E-46 T 29-03-2018 MC49_RS02995 dace4ba185a4b78ca38ef754e3c36e45 441 SUPERFAMILY SSF53187 324 412 1.03E-46 T 29-03-2018 MC49_RS02995 dace4ba185a4b78ca38ef754e3c36e45 441 SUPERFAMILY SSF55031 208 323 8.37E-19 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain MC49_RS02995 dace4ba185a4b78ca38ef754e3c36e45 441 Gene3D G3DSA:3.40.630.10 1 292 6.8E-32 T 29-03-2018 MC49_RS02995 dace4ba185a4b78ca38ef754e3c36e45 441 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 25 378 1.0E-48 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 MC49_RS02995 dace4ba185a4b78ca38ef754e3c36e45 441 Pfam PF07687 Peptidase dimerisation domain 207 288 2.3E-4 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain MC49_RS02995 dace4ba185a4b78ca38ef754e3c36e45 441 Gene3D G3DSA:3.40.630.10 293 424 2.3E-14 T 29-03-2018 MC49_RS00595 a740212dc531c8e58a44bc8f425b66e4 214 Pfam PF00406 Adenylate kinase 5 186 1.1E-59 T 29-03-2018 MC49_RS00595 a740212dc531c8e58a44bc8f425b66e4 214 Hamap MF_00235 Adenylate kinase [adk]. 1 214 51.501 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MC49_RS00595 a740212dc531c8e58a44bc8f425b66e4 214 PRINTS PR00094 Adenylate kinase signature 81 97 5.7E-36 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MC49_RS00595 a740212dc531c8e58a44bc8f425b66e4 214 PRINTS PR00094 Adenylate kinase signature 4 17 5.7E-36 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MC49_RS00595 a740212dc531c8e58a44bc8f425b66e4 214 PRINTS PR00094 Adenylate kinase signature 32 46 5.7E-36 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MC49_RS00595 a740212dc531c8e58a44bc8f425b66e4 214 PRINTS PR00094 Adenylate kinase signature 173 187 5.7E-36 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MC49_RS00595 a740212dc531c8e58a44bc8f425b66e4 214 PRINTS PR00094 Adenylate kinase signature 156 171 5.7E-36 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MC49_RS00595 a740212dc531c8e58a44bc8f425b66e4 214 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 29-03-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MC49_RS00595 a740212dc531c8e58a44bc8f425b66e4 214 Gene3D G3DSA:3.40.50.300 1 214 3.4E-67 T 29-03-2018 MC49_RS00595 a740212dc531c8e58a44bc8f425b66e4 214 SUPERFAMILY SSF52540 1 212 4.51E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS00595 a740212dc531c8e58a44bc8f425b66e4 214 TIGRFAM TIGR01351 adk: adenylate kinase 2 212 2.3E-75 T 29-03-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 MC49_RS00595 a740212dc531c8e58a44bc8f425b66e4 214 Pfam PF05191 Adenylate kinase, active site lid 123 158 3.1E-15 T 29-03-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 MC49_RS15330 ec2b64b1ab9a266218c04880f0e6037c 215 Pfam PF01914 MarC family integral membrane protein 9 209 3.9E-63 T 29-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 MC49_RS15330 ec2b64b1ab9a266218c04880f0e6037c 215 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 8 206 3.6E-69 T 29-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 MC49_RS15735 68f2850e40cab421617299e41988e694 192 PIRSF PIRSF000349 1 192 3.4E-85 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MC49_RS15735 68f2850e40cab421617299e41988e694 192 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 89 189 5.7E-41 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MC49_RS15735 68f2850e40cab421617299e41988e694 192 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 2 82 1.9E-33 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MC49_RS15735 68f2850e40cab421617299e41988e694 192 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 1.4E-21 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MC49_RS15735 68f2850e40cab421617299e41988e694 192 PRINTS PR01703 Manganese superoxide dismutase signature 118 126 1.4E-21 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MC49_RS15735 68f2850e40cab421617299e41988e694 192 PRINTS PR01703 Manganese superoxide dismutase signature 65 78 1.4E-21 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MC49_RS15735 68f2850e40cab421617299e41988e694 192 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 1.4E-21 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MC49_RS15735 68f2850e40cab421617299e41988e694 192 PRINTS PR01703 Manganese superoxide dismutase signature 155 167 1.4E-21 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MC49_RS15735 68f2850e40cab421617299e41988e694 192 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 157 164 - T 29-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MC49_RS15735 68f2850e40cab421617299e41988e694 192 SUPERFAMILY SSF46609 1 84 7.86E-35 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MC49_RS15735 68f2850e40cab421617299e41988e694 192 Gene3D G3DSA:1.10.287.990 20 82 9.9E-27 T 29-03-2018 MC49_RS15735 68f2850e40cab421617299e41988e694 192 SUPERFAMILY SSF54719 82 191 8.12E-44 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MC49_RS04580 1a6fded0f8ae81afb01c9b06450c8e60 381 Gene3D G3DSA:3.90.1150.10 249 381 1.2E-48 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS04580 1a6fded0f8ae81afb01c9b06450c8e60 381 Gene3D G3DSA:3.40.640.10 3 248 7.3E-55 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS04580 1a6fded0f8ae81afb01c9b06450c8e60 381 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 6 380 1.8E-138 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MC49_RS04580 1a6fded0f8ae81afb01c9b06450c8e60 381 SUPERFAMILY SSF53383 23 380 1.53E-109 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS04580 1a6fded0f8ae81afb01c9b06450c8e60 381 PIRSF PIRSF001434 1 381 1.4E-135 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MC49_RS05205 ac2a3272d5161eb67160d914d1aa4e24 552 SMART SM00382 128 291 1.4E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS05205 ac2a3272d5161eb67160d914d1aa4e24 552 Pfam PF11426 Tn7 transposition regulator TnsC 505 549 8.6E-12 T 29-03-2018 IPR021542 Tn7 transposition regulator TnsC MC49_RS05205 ac2a3272d5161eb67160d914d1aa4e24 552 Gene3D G3DSA:3.40.50.300 52 287 2.5E-9 T 29-03-2018 MC49_RS05205 ac2a3272d5161eb67160d914d1aa4e24 552 SUPERFAMILY SSF52540 128 377 1.41E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS05205 ac2a3272d5161eb67160d914d1aa4e24 552 Pfam PF13401 AAA domain 127 276 9.2E-30 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS18435 29a50540f6e40b628d62dc9a2ffd6b36 958 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 8 957 25.112 T 29-03-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MC49_RS18435 29a50540f6e40b628d62dc9a2ffd6b36 958 Gene3D G3DSA:3.40.640.10 521 773 3.0E-41 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS18435 29a50540f6e40b628d62dc9a2ffd6b36 958 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 17 951 0.0 T 29-03-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MC49_RS18435 29a50540f6e40b628d62dc9a2ffd6b36 958 SUPERFAMILY SSF53383 930 952 3.6E-98 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS18435 29a50540f6e40b628d62dc9a2ffd6b36 958 SUPERFAMILY SSF53383 462 888 3.6E-98 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS18435 29a50540f6e40b628d62dc9a2ffd6b36 958 Gene3D G3DSA:3.40.640.10 96 342 6.5E-33 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS18435 29a50540f6e40b628d62dc9a2ffd6b36 958 Gene3D G3DSA:3.90.1150.10 774 906 3.3E-42 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS18435 29a50540f6e40b628d62dc9a2ffd6b36 958 Gene3D G3DSA:3.90.1150.10 343 444 4.7E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS18435 29a50540f6e40b628d62dc9a2ffd6b36 958 Pfam PF02347 Glycine cleavage system P-protein 16 440 3.5E-179 T 29-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MC49_RS18435 29a50540f6e40b628d62dc9a2ffd6b36 958 Pfam PF02347 Glycine cleavage system P-protein 461 743 3.5E-9 T 29-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MC49_RS18435 29a50540f6e40b628d62dc9a2ffd6b36 958 SUPERFAMILY SSF53383 17 440 4.7E-98 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS00530 126540accf18659539b4adbf754ebca3 562 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 215 525 3.7E-87 T 29-03-2018 IPR005565 Haemolysin activator HlyB, C-terminal MC49_RS00530 126540accf18659539b4adbf754ebca3 562 Pfam PF08479 POTRA domain, ShlB-type 85 158 3.9E-13 T 29-03-2018 IPR013686 Polypeptide-transport-associated, ShlB-type MC49_RS00530 126540accf18659539b4adbf754ebca3 562 Pfam PF17287 POTRA domain 161 210 4.7E-15 T 29-03-2018 IPR035251 ShlB, POTRA domain MC49_RS00530 126540accf18659539b4adbf754ebca3 562 Gene3D G3DSA:2.40.160.50 184 562 4.6E-35 T 29-03-2018 MC49_RS00530 126540accf18659539b4adbf754ebca3 562 PIRSF PIRSF029745 3 562 1.8E-120 T 29-03-2018 IPR027282 Two partner secretion pathway transporter GO:0015031 MC49_RS00530 126540accf18659539b4adbf754ebca3 562 Gene3D G3DSA:3.10.20.310 89 158 4.5E-5 T 29-03-2018 MC49_RS09875 baaf296d4692910e2302cf3883063bc7 82 ProSitePatterns PS00732 Ribosomal protein S16 signature. 2 11 - T 29-03-2018 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS09875 baaf296d4692910e2302cf3883063bc7 82 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 1 78 23.804 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS09875 baaf296d4692910e2302cf3883063bc7 82 Pfam PF00886 Ribosomal protein S16 8 68 3.1E-24 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS09875 baaf296d4692910e2302cf3883063bc7 82 SUPERFAMILY SSF54565 1 76 1.02E-28 T 29-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS09875 baaf296d4692910e2302cf3883063bc7 82 Gene3D G3DSA:3.30.1320.10 1 79 1.8E-31 T 29-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS09875 baaf296d4692910e2302cf3883063bc7 82 TIGRFAM TIGR00002 S16: ribosomal protein bS16 2 79 1.7E-28 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS02050 830466704fc75314164301b9b3f88c9e 480 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 217 238 2.0E-30 T 29-03-2018 MC49_RS02050 830466704fc75314164301b9b3f88c9e 480 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 156 177 2.0E-30 T 29-03-2018 MC49_RS02050 830466704fc75314164301b9b3f88c9e 480 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 308 320 2.0E-30 T 29-03-2018 MC49_RS02050 830466704fc75314164301b9b3f88c9e 480 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 76 101 2.0E-30 T 29-03-2018 MC49_RS02050 830466704fc75314164301b9b3f88c9e 480 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 110 130 2.0E-30 T 29-03-2018 MC49_RS02050 830466704fc75314164301b9b3f88c9e 480 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 239 265 2.0E-30 T 29-03-2018 MC49_RS02050 830466704fc75314164301b9b3f88c9e 480 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 71 120 1.6E-8 T 29-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS02050 830466704fc75314164301b9b3f88c9e 480 Pfam PF00361 Proton-conducting membrane transporter 137 416 1.1E-59 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS00685 4aa6f66a62a1d31f673a722151f5470b 429 Pfam PF00909 Ammonium Transporter Family 34 426 1.7E-120 T 29-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 MC49_RS00685 4aa6f66a62a1d31f673a722151f5470b 429 TIGRFAM TIGR00836 amt: ammonium transporter 31 426 7.8E-132 T 29-03-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 MC49_RS00685 4aa6f66a62a1d31f673a722151f5470b 429 SUPERFAMILY SSF111352 28 406 2.62E-123 T 29-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 MC49_RS00685 4aa6f66a62a1d31f673a722151f5470b 429 Gene3D G3DSA:1.10.3430.10 23 407 1.4E-126 T 29-03-2018 MC49_RS00685 4aa6f66a62a1d31f673a722151f5470b 429 ProSitePatterns PS01219 Ammonium transporters signature. 182 207 - T 29-03-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 MC49_RS00685 4aa6f66a62a1d31f673a722151f5470b 429 PRINTS PR00342 Rhesus blood group protein signature 252 274 4.8E-5 T 29-03-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 MC49_RS00685 4aa6f66a62a1d31f673a722151f5470b 429 PRINTS PR00342 Rhesus blood group protein signature 126 142 4.8E-5 T 29-03-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 MC49_RS00685 4aa6f66a62a1d31f673a722151f5470b 429 PRINTS PR00342 Rhesus blood group protein signature 307 325 4.8E-5 T 29-03-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 MC49_RS00685 4aa6f66a62a1d31f673a722151f5470b 429 PRINTS PR00342 Rhesus blood group protein signature 221 239 4.8E-5 T 29-03-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 MC49_RS15310 4c2918835aaf48735170c300491170e0 348 SUPERFAMILY SSF161098 103 172 1.7E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS15310 4c2918835aaf48735170c300491170e0 348 SUPERFAMILY SSF161098 211 331 1.7E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS15310 4c2918835aaf48735170c300491170e0 348 Gene3D G3DSA:1.10.3720.10 96 345 6.0E-38 T 29-03-2018 MC49_RS15310 4c2918835aaf48735170c300491170e0 348 Gene3D G3DSA:1.10.3720.10 3 69 0.3 T 29-03-2018 MC49_RS15310 4c2918835aaf48735170c300491170e0 348 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 126 347 1.7E-41 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS18620 8c40b8ba27c6a2ea20e42a5fe68a909f 305 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 4 276 7.6E-108 T 29-03-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 MC49_RS18620 8c40b8ba27c6a2ea20e42a5fe68a909f 305 SUPERFAMILY SSF54211 134 278 6.9E-54 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MC49_RS18620 8c40b8ba27c6a2ea20e42a5fe68a909f 305 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 2 301 1.0E-155 T 29-03-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 MC49_RS18620 8c40b8ba27c6a2ea20e42a5fe68a909f 305 SUPERFAMILY SSF54211 3 124 2.65E-41 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MC49_RS18620 8c40b8ba27c6a2ea20e42a5fe68a909f 305 Hamap MF_00388 UDP-3-O-acyl-N-acetylglucosamine deacetylase [lpxC]. 2 280 45.952 T 29-03-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 MC49_RS18620 8c40b8ba27c6a2ea20e42a5fe68a909f 305 Gene3D G3DSA:3.30.230.20 1 128 1.2E-48 T 29-03-2018 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 MC49_RS18620 8c40b8ba27c6a2ea20e42a5fe68a909f 305 Gene3D G3DSA:3.30.1700.10 129 299 1.4E-69 T 29-03-2018 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 MC49_RS11200 0cb0b781b998748063340f0b855d6c5e 237 PIRSF PIRSF017818 1 237 6.6E-122 T 29-03-2018 IPR010025 HAD-superfamily phosphatase, subfamily IIIB, AphA GO:0003993|GO:0030288 KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 MC49_RS11200 0cb0b781b998748063340f0b855d6c5e 237 TIGRFAM TIGR01672 AphA: HAD phosphatase, family IIIB 1 237 3.0E-97 T 29-03-2018 IPR010025 HAD-superfamily phosphatase, subfamily IIIB, AphA GO:0003993|GO:0030288 KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 MC49_RS11200 0cb0b781b998748063340f0b855d6c5e 237 SUPERFAMILY SSF56784 32 237 1.83E-71 T 29-03-2018 IPR023214 HAD-like domain MC49_RS11200 0cb0b781b998748063340f0b855d6c5e 237 Pfam PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) 11 220 1.1E-36 T 29-03-2018 IPR005519 Acid phosphatase, class B-like MC49_RS11200 0cb0b781b998748063340f0b855d6c5e 237 Gene3D G3DSA:3.40.50.1000 27 237 3.9E-32 T 29-03-2018 IPR023214 HAD-like domain MC49_RS16525 bceb3b0b89dbad59c84bfbeefad53349 598 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 251 262 - T 29-03-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16525 bceb3b0b89dbad59c84bfbeefad53349 598 Gene3D G3DSA:1.10.645.10 210 409 9.7E-47 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16525 bceb3b0b89dbad59c84bfbeefad53349 598 Hamap MF_01359 NADH-quinone oxidoreductase subunit C/D [nuoC]. 15 598 71.922 T 29-03-2018 IPR023062 NADH dehydrogenase, subunit CD GO:0030964|GO:0050136|GO:0055114 KEGG: 00190+1.6.5.11 MC49_RS16525 bceb3b0b89dbad59c84bfbeefad53349 598 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 48 175 6.0E-42 T 29-03-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16525 bceb3b0b89dbad59c84bfbeefad53349 598 SUPERFAMILY SSF143243 24 228 9.15E-60 T 29-03-2018 MC49_RS16525 bceb3b0b89dbad59c84bfbeefad53349 598 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 49 176 8.7E-39 T 29-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16525 bceb3b0b89dbad59c84bfbeefad53349 598 Gene3D G3DSA:1.10.645.10 410 594 4.6E-32 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16525 bceb3b0b89dbad59c84bfbeefad53349 598 SUPERFAMILY SSF56762 224 598 9.55E-122 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16525 bceb3b0b89dbad59c84bfbeefad53349 598 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 214 598 7.5E-176 T 29-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16525 bceb3b0b89dbad59c84bfbeefad53349 598 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 137 158 - T 29-03-2018 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16525 bceb3b0b89dbad59c84bfbeefad53349 598 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 104 159 2.0E-21 T 29-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16525 bceb3b0b89dbad59c84bfbeefad53349 598 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 210 598 41.85 T 29-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16525 bceb3b0b89dbad59c84bfbeefad53349 598 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 328 598 4.9E-104 T 29-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS08920 7f6a0426a7bee47407bf43258a7b80bf 339 PIRSF PIRSF038991 1 339 2.1E-45 T 29-03-2018 IPR007820 AbrB family GO:0010468|GO:0016021 MC49_RS08920 7f6a0426a7bee47407bf43258a7b80bf 339 Pfam PF05145 Transition state regulatory protein AbrB 29 331 8.3E-59 T 29-03-2018 IPR007820 AbrB family GO:0010468|GO:0016021 MC49_RS03050 600130d1a5aaf3ea6d614e054f2addad 321 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 253 266 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MC49_RS03050 600130d1a5aaf3ea6d614e054f2addad 321 SUPERFAMILY SSF53613 3 303 6.7E-48 T 29-03-2018 IPR029056 Ribokinase-like MC49_RS03050 600130d1a5aaf3ea6d614e054f2addad 321 Pfam PF00294 pfkB family carbohydrate kinase 18 301 5.1E-30 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB MC49_RS03050 600130d1a5aaf3ea6d614e054f2addad 321 Gene3D G3DSA:3.40.1190.20 1 321 3.4E-43 T 29-03-2018 IPR029056 Ribokinase-like MC49_RS18020 b0745bff7b97d7ea7f1afeb9ced87b62 85 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 29-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site MC49_RS18020 b0745bff7b97d7ea7f1afeb9ced87b62 85 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 1.5E-29 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like MC49_RS18020 b0745bff7b97d7ea7f1afeb9ced87b62 85 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 29-03-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site MC49_RS18020 b0745bff7b97d7ea7f1afeb9ced87b62 85 PRINTS PR00107 Phosphocarrier protein signature 13 29 2.4E-19 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like MC49_RS18020 b0745bff7b97d7ea7f1afeb9ced87b62 85 PRINTS PR00107 Phosphocarrier protein signature 53 70 2.4E-19 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like MC49_RS18020 b0745bff7b97d7ea7f1afeb9ced87b62 85 PRINTS PR00107 Phosphocarrier protein signature 38 53 2.4E-19 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like MC49_RS18020 b0745bff7b97d7ea7f1afeb9ced87b62 85 Gene3D G3DSA:3.30.1340.10 1 85 8.4E-32 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like MC49_RS18020 b0745bff7b97d7ea7f1afeb9ced87b62 85 SUPERFAMILY SSF55594 1 81 3.79E-27 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like MC49_RS18020 b0745bff7b97d7ea7f1afeb9ced87b62 85 Pfam PF00381 PTS HPr component phosphorylation site 3 81 7.1E-28 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like MC49_RS00835 5417503366cdf6be084e9b2ebb97188e 84 Gene3D G3DSA:1.10.287.1040 12 76 1.0E-22 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MC49_RS00835 5417503366cdf6be084e9b2ebb97188e 84 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 14 56 3.0E-9 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MC49_RS00835 5417503366cdf6be084e9b2ebb97188e 84 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 14 74 14.974 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MC49_RS00835 5417503366cdf6be084e9b2ebb97188e 84 SUPERFAMILY SSF116842 8 77 1.24E-19 T 29-03-2018 MC49_RS00835 5417503366cdf6be084e9b2ebb97188e 84 Pfam PF02609 Exonuclease VII small subunit 15 66 1.1E-17 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MC49_RS00835 5417503366cdf6be084e9b2ebb97188e 84 PIRSF PIRSF006488 2 84 3.4E-21 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MC49_RS00835 5417503366cdf6be084e9b2ebb97188e 84 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 14 69 1.8E-21 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MC49_RS03640 c8d5b0e9b210613c8803cc0ef3c0dbdd 181 SUPERFAMILY SSF53098 4 180 1.08E-50 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MC49_RS03640 c8d5b0e9b210613c8803cc0ef3c0dbdd 181 Hamap MF_00045 Oligoribonuclease [orn]. 3 181 44.723 T 29-03-2018 IPR022894 Oligoribonuclease GO:0000175 MC49_RS03640 c8d5b0e9b210613c8803cc0ef3c0dbdd 181 Pfam PF00929 Exonuclease 9 170 1.6E-38 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MC49_RS03640 c8d5b0e9b210613c8803cc0ef3c0dbdd 181 SMART SM00479 7 180 1.8E-24 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MC49_RS03640 c8d5b0e9b210613c8803cc0ef3c0dbdd 181 Gene3D G3DSA:3.30.420.10 2 181 1.2E-29 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MC49_RS15125 0b9b9d58fd9fbaaedd55af3d75109209 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 162 1.0E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS15125 0b9b9d58fd9fbaaedd55af3d75109209 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 191 1.0E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS15125 0b9b9d58fd9fbaaedd55af3d75109209 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 1.0E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS15125 0b9b9d58fd9fbaaedd55af3d75109209 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 21 38 1.0E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS15125 0b9b9d58fd9fbaaedd55af3d75109209 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 98 109 1.0E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS15125 0b9b9d58fd9fbaaedd55af3d75109209 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 193 210 1.0E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS15125 0b9b9d58fd9fbaaedd55af3d75109209 260 SUPERFAMILY SSF51735 16 249 4.31E-61 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS15125 0b9b9d58fd9fbaaedd55af3d75109209 260 Gene3D G3DSA:3.40.50.720 10 257 2.8E-58 T 29-03-2018 MC49_RS15125 0b9b9d58fd9fbaaedd55af3d75109209 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 159 187 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MC49_RS15125 0b9b9d58fd9fbaaedd55af3d75109209 260 Pfam PF00106 short chain dehydrogenase 20 216 1.8E-47 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS15125 0b9b9d58fd9fbaaedd55af3d75109209 260 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 20 206 5.9E-4 T 29-03-2018 MC49_RS07570 4cd7887201eda7f7748ea52f34d14dad 640 SUPERFAMILY SSF100934 535 608 5.1E-5 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain MC49_RS07570 4cd7887201eda7f7748ea52f34d14dad 640 PRINTS PR00301 70kDa heat shock protein signature 198 208 2.8E-80 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MC49_RS07570 4cd7887201eda7f7748ea52f34d14dad 640 PRINTS PR00301 70kDa heat shock protein signature 469 485 2.8E-80 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MC49_RS07570 4cd7887201eda7f7748ea52f34d14dad 640 PRINTS PR00301 70kDa heat shock protein signature 138 158 2.8E-80 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MC49_RS07570 4cd7887201eda7f7748ea52f34d14dad 640 PRINTS PR00301 70kDa heat shock protein signature 3 16 2.8E-80 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MC49_RS07570 4cd7887201eda7f7748ea52f34d14dad 640 PRINTS PR00301 70kDa heat shock protein signature 31 43 2.8E-80 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MC49_RS07570 4cd7887201eda7f7748ea52f34d14dad 640 PRINTS PR00301 70kDa heat shock protein signature 54 62 2.8E-80 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MC49_RS07570 4cd7887201eda7f7748ea52f34d14dad 640 PRINTS PR00301 70kDa heat shock protein signature 365 385 2.8E-80 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MC49_RS07570 4cd7887201eda7f7748ea52f34d14dad 640 PRINTS PR00301 70kDa heat shock protein signature 334 350 2.8E-80 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MC49_RS07570 4cd7887201eda7f7748ea52f34d14dad 640 PRINTS PR00301 70kDa heat shock protein signature 388 407 2.8E-80 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MC49_RS07570 4cd7887201eda7f7748ea52f34d14dad 640 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MC49_RS07570 4cd7887201eda7f7748ea52f34d14dad 640 Gene3D G3DSA:3.30.420.40 1 196 4.8E-82 T 29-03-2018 MC49_RS07570 4cd7887201eda7f7748ea52f34d14dad 640 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 192 205 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MC49_RS07570 4cd7887201eda7f7748ea52f34d14dad 640 Pfam PF00012 Hsp70 protein 4 601 1.4E-262 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MC49_RS07570 4cd7887201eda7f7748ea52f34d14dad 640 Gene3D G3DSA:1.20.1270.10 532 619 4.1E-18 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain MC49_RS07570 4cd7887201eda7f7748ea52f34d14dad 640 SUPERFAMILY SSF100920 384 540 3.66E-60 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 MC49_RS07570 4cd7887201eda7f7748ea52f34d14dad 640 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 633 36.822 T 29-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 MC49_RS07570 4cd7887201eda7f7748ea52f34d14dad 640 Gene3D G3DSA:2.60.34.10 390 531 4.9E-63 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 MC49_RS07570 4cd7887201eda7f7748ea52f34d14dad 640 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 337 351 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MC49_RS07570 4cd7887201eda7f7748ea52f34d14dad 640 Gene3D G3DSA:3.30.420.40 197 366 1.5E-45 T 29-03-2018 MC49_RS07570 4cd7887201eda7f7748ea52f34d14dad 640 SUPERFAMILY SSF53067 187 382 9.26E-68 T 29-03-2018 MC49_RS07570 4cd7887201eda7f7748ea52f34d14dad 640 SUPERFAMILY SSF53067 4 183 1.68E-66 T 29-03-2018 MC49_RS07570 4cd7887201eda7f7748ea52f34d14dad 640 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 603 1.1E-290 T 29-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 MC49_RS04690 e29bc8296ee3e69f248089bf89634e70 272 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 178 184 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MC49_RS04690 e29bc8296ee3e69f248089bf89634e70 272 Gene3D G3DSA:3.40.50.150 154 270 7.9E-15 T 29-03-2018 MC49_RS04690 e29bc8296ee3e69f248089bf89634e70 272 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 10 26 3.2E-19 T 29-03-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 MC49_RS04690 e29bc8296ee3e69f248089bf89634e70 272 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 175 187 3.2E-19 T 29-03-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 MC49_RS04690 e29bc8296ee3e69f248089bf89634e70 272 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 31 45 3.2E-19 T 29-03-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 MC49_RS04690 e29bc8296ee3e69f248089bf89634e70 272 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 50 63 3.2E-19 T 29-03-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 MC49_RS04690 e29bc8296ee3e69f248089bf89634e70 272 Gene3D G3DSA:1.10.1020.10 57 153 7.7E-35 T 29-03-2018 IPR023095 Adenine-specific methyltransferase, domain 2 GO:0009007 MC49_RS04690 e29bc8296ee3e69f248089bf89634e70 272 Pfam PF02086 D12 class N6 adenine-specific DNA methyltransferase 10 252 2.3E-72 T 29-03-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 MC49_RS04690 e29bc8296ee3e69f248089bf89634e70 272 TIGRFAM TIGR00571 dam: DNA adenine methylase 5 268 1.8E-96 T 29-03-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 MC49_RS04690 e29bc8296ee3e69f248089bf89634e70 272 PIRSF PIRSF000398 1 271 2.3E-67 T 29-03-2018 IPR012263 Adenine modification methylase, M.EcoRV-type GO:0009007|GO:0032775 MC49_RS04690 e29bc8296ee3e69f248089bf89634e70 272 SUPERFAMILY SSF53335 5 268 2.5E-77 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS10575 f7cce19bf9302ce5e14739e6ec7f6e00 345 Gene3D G3DSA:3.20.20.70 4 315 3.1E-59 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS10575 f7cce19bf9302ce5e14739e6ec7f6e00 345 SUPERFAMILY SSF102114 5 310 2.62E-92 T 29-03-2018 MC49_RS10575 f7cce19bf9302ce5e14739e6ec7f6e00 345 Hamap MF_01694 Biotin synthase [bioB]. 5 313 41.842 T 29-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MC49_RS10575 f7cce19bf9302ce5e14739e6ec7f6e00 345 TIGRFAM TIGR00433 bioB: biotin synthase 15 310 4.8E-125 T 29-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MC49_RS10575 f7cce19bf9302ce5e14739e6ec7f6e00 345 Pfam PF04055 Radical SAM superfamily 50 204 3.4E-16 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MC49_RS10575 f7cce19bf9302ce5e14739e6ec7f6e00 345 SMART SM00876 220 312 8.9E-46 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MC49_RS10575 f7cce19bf9302ce5e14739e6ec7f6e00 345 PIRSF PIRSF001619 1 318 4.3E-138 T 29-03-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MC49_RS10575 f7cce19bf9302ce5e14739e6ec7f6e00 345 SMART SM00729 43 255 3.3E-38 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MC49_RS10575 f7cce19bf9302ce5e14739e6ec7f6e00 345 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 220 310 1.4E-19 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MC49_RS06370 3d25d2c3838991436a582a3dbbaf0010 96 TIGRFAM TIGR03011 sulf_tusB_dsrH: sulfur relay protein TusB/DsrH 2 95 1.5E-26 T 29-03-2018 IPR007215 Sulphur relay, TusB/DsrH GO:0002143|GO:0005737 MC49_RS06370 3d25d2c3838991436a582a3dbbaf0010 96 Gene3D G3DSA:3.40.1260.10 1 92 1.7E-19 T 29-03-2018 MC49_RS06370 3d25d2c3838991436a582a3dbbaf0010 96 SUPERFAMILY SSF75169 1 95 8.1E-27 T 29-03-2018 IPR027396 DsrEFH-like MC49_RS06370 3d25d2c3838991436a582a3dbbaf0010 96 Pfam PF04077 DsrH like protein 8 91 3.4E-24 T 29-03-2018 IPR007215 Sulphur relay, TusB/DsrH GO:0002143|GO:0005737 MC49_RS14320 661015401d873893e8d35590d36cd7e5 378 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 282 1.5E-47 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS14320 661015401d873893e8d35590d36cd7e5 378 Gene3D G3DSA:3.50.50.60 101 237 1.8E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS14320 661015401d873893e8d35590d36cd7e5 378 Gene3D G3DSA:3.50.50.60 238 302 9.0E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS14320 661015401d873893e8d35590d36cd7e5 378 Gene3D G3DSA:3.50.50.60 2 100 1.8E-8 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS14320 661015401d873893e8d35590d36cd7e5 378 SUPERFAMILY SSF51905 4 301 8.87E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS14320 661015401d873893e8d35590d36cd7e5 378 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 2.4E-20 T 29-03-2018 MC49_RS14320 661015401d873893e8d35590d36cd7e5 378 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 143 161 2.4E-20 T 29-03-2018 MC49_RS14320 661015401d873893e8d35590d36cd7e5 378 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 2.4E-20 T 29-03-2018 MC49_RS14320 661015401d873893e8d35590d36cd7e5 378 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 228 244 2.4E-20 T 29-03-2018 MC49_RS14320 661015401d873893e8d35590d36cd7e5 378 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 2.4E-20 T 29-03-2018 MC49_RS14320 661015401d873893e8d35590d36cd7e5 378 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 168 1.6E-13 T 29-03-2018 MC49_RS14320 661015401d873893e8d35590d36cd7e5 378 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 229 243 1.6E-13 T 29-03-2018 MC49_RS14320 661015401d873893e8d35590d36cd7e5 378 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 275 1.6E-13 T 29-03-2018 MC49_RS14320 661015401d873893e8d35590d36cd7e5 378 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.6E-13 T 29-03-2018 MC49_RS05770 0258c402d62ba77d123a1a40024609c7 456 Gene3D G3DSA:1.10.287.130 228 296 2.0E-15 T 29-03-2018 MC49_RS05770 0258c402d62ba77d123a1a40024609c7 456 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 348 453 1.5E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS05770 0258c402d62ba77d123a1a40024609c7 456 Pfam PF00672 HAMP domain 184 234 2.2E-6 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MC49_RS05770 0258c402d62ba77d123a1a40024609c7 456 SMART SM00387 345 455 2.1E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS05770 0258c402d62ba77d123a1a40024609c7 456 SMART SM00388 238 300 8.5E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS05770 0258c402d62ba77d123a1a40024609c7 456 Pfam PF00512 His Kinase A (phospho-acceptor) domain 239 298 1.2E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS05770 0258c402d62ba77d123a1a40024609c7 456 Gene3D G3DSA:3.30.565.10 303 456 7.0E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS05770 0258c402d62ba77d123a1a40024609c7 456 SUPERFAMILY SSF47384 224 299 2.16E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS05770 0258c402d62ba77d123a1a40024609c7 456 SMART SM00304 184 237 1.2E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MC49_RS05770 0258c402d62ba77d123a1a40024609c7 456 Pfam PF16527 Two-component sensor protein CpxA, periplasmic domain 81 145 5.0E-9 T 29-03-2018 IPR032404 Two-component sensor protein CpxA, periplasmic domain MC49_RS05770 0258c402d62ba77d123a1a40024609c7 456 SUPERFAMILY SSF55874 289 453 1.03E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS05770 0258c402d62ba77d123a1a40024609c7 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 408 5.8E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS05770 0258c402d62ba77d123a1a40024609c7 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 433 5.8E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS05770 0258c402d62ba77d123a1a40024609c7 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 452 5.8E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS05770 0258c402d62ba77d123a1a40024609c7 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 380 394 5.8E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS17385 dc3a8cc23c6b108bbe275d1b3543a2e8 457 SUPERFAMILY SSF102114 155 371 1.01E-27 T 29-03-2018 MC49_RS17385 dc3a8cc23c6b108bbe275d1b3543a2e8 457 Gene3D G3DSA:3.20.20.70 134 440 4.9E-26 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS17385 dc3a8cc23c6b108bbe275d1b3543a2e8 457 Gene3D G3DSA:3.40.50.280 26 133 2.9E-5 T 29-03-2018 MC49_RS17385 dc3a8cc23c6b108bbe275d1b3543a2e8 457 SMART SM00729 172 378 9.3E-14 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MC49_RS17385 dc3a8cc23c6b108bbe275d1b3543a2e8 457 Pfam PF04055 Radical SAM superfamily 180 334 4.7E-11 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MC49_RS17385 dc3a8cc23c6b108bbe275d1b3543a2e8 457 Pfam PF13282 Domain of unknown function (DUF4070) 354 413 6.3E-6 T 29-03-2018 IPR025274 Domain of unknown function DUF4070 MC49_RS14960 29d7e15b083dd877ad2079be78bb4322 399 Gene3D G3DSA:3.30.420.40 80 204 3.5E-12 T 29-03-2018 MC49_RS14960 29d7e15b083dd877ad2079be78bb4322 399 SUPERFAMILY SSF46785 11 78 5.45E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS14960 29d7e15b083dd877ad2079be78bb4322 399 Gene3D G3DSA:1.10.10.10 11 79 2.4E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS14960 29d7e15b083dd877ad2079be78bb4322 399 Pfam PF00480 ROK family 88 383 6.4E-43 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 MC49_RS14960 29d7e15b083dd877ad2079be78bb4322 399 SUPERFAMILY SSF53067 86 388 5.19E-40 T 29-03-2018 MC49_RS14960 29d7e15b083dd877ad2079be78bb4322 399 Gene3D G3DSA:3.30.420.40 205 387 4.9E-40 T 29-03-2018 MC49_RS10500 424e137232aeb0efa95008ee89a6e0d7 350 Pfam PF00793 DAHP synthetase I family 40 338 1.3E-110 T 29-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 MC49_RS10500 424e137232aeb0efa95008ee89a6e0d7 350 PIRSF PIRSF001361 1 350 6.7E-166 T 29-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 MC49_RS10500 424e137232aeb0efa95008ee89a6e0d7 350 SUPERFAMILY SSF51569 7 348 1.26E-140 T 29-03-2018 MC49_RS10500 424e137232aeb0efa95008ee89a6e0d7 350 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 6 349 3.9E-178 T 29-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 MC49_RS10500 424e137232aeb0efa95008ee89a6e0d7 350 Gene3D G3DSA:3.20.20.70 8 350 2.4E-134 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS12620 b1057f8579a4f059f5a0987277d2b32d 147 TIGRFAM TIGR02473 flagell_FliJ: flagellar export protein FliJ 5 141 2.8E-30 T 29-03-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 MC49_RS12620 b1057f8579a4f059f5a0987277d2b32d 147 PRINTS PR01004 Flagellar FliJ protein signature 4 26 1.3E-28 T 29-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 MC49_RS12620 b1057f8579a4f059f5a0987277d2b32d 147 PRINTS PR01004 Flagellar FliJ protein signature 44 61 1.3E-28 T 29-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 MC49_RS12620 b1057f8579a4f059f5a0987277d2b32d 147 PRINTS PR01004 Flagellar FliJ protein signature 63 84 1.3E-28 T 29-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 MC49_RS12620 b1057f8579a4f059f5a0987277d2b32d 147 PRINTS PR01004 Flagellar FliJ protein signature 126 146 1.3E-28 T 29-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 MC49_RS12620 b1057f8579a4f059f5a0987277d2b32d 147 PRINTS PR01004 Flagellar FliJ protein signature 27 43 1.3E-28 T 29-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 MC49_RS12620 b1057f8579a4f059f5a0987277d2b32d 147 PRINTS PR01004 Flagellar FliJ protein signature 86 107 1.3E-28 T 29-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 MC49_RS12620 b1057f8579a4f059f5a0987277d2b32d 147 Pfam PF02050 Flagellar FliJ protein 19 141 6.2E-32 T 29-03-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 MC49_RS12620 b1057f8579a4f059f5a0987277d2b32d 147 PIRSF PIRSF019404 1 147 5.9E-45 T 29-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 MC49_RS11295 84bb749e7966428a4e515e1fadb94ac3 172 Hamap MF_00405 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase [fabA]. 2 172 49.325 T 29-03-2018 IPR010083 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA GO:0005737|GO:0006633|GO:0008693 KEGG: 00061+4.2.1.59+5.3.3.14|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MC49_RS11295 84bb749e7966428a4e515e1fadb94ac3 172 Gene3D G3DSA:3.10.129.10 1 172 3.9E-49 T 29-03-2018 MC49_RS11295 84bb749e7966428a4e515e1fadb94ac3 172 Pfam PF07977 FabA-like domain 29 158 7.4E-53 T 29-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MC49_RS11295 84bb749e7966428a4e515e1fadb94ac3 172 TIGRFAM TIGR01749 fabA: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA 4 172 2.4E-89 T 29-03-2018 IPR010083 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA GO:0005737|GO:0006633|GO:0008693 KEGG: 00061+4.2.1.59+5.3.3.14|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MC49_RS11295 84bb749e7966428a4e515e1fadb94ac3 172 SUPERFAMILY SSF54637 4 169 6.71E-55 T 29-03-2018 IPR029069 HotDog domain MC49_RS16140 37cbd1fd13497399c3ed33a43c3ee767 349 PIRSF PIRSF026343 9 346 8.8E-102 T 29-03-2018 IPR014524 Outer membrane protein assembly factor BamC MC49_RS16140 37cbd1fd13497399c3ed33a43c3ee767 349 Hamap MF_00924 Outer membrane protein assembly factor BamC [bamC]. 9 344 34.909 T 29-03-2018 IPR014524 Outer membrane protein assembly factor BamC MC49_RS16140 37cbd1fd13497399c3ed33a43c3ee767 349 Pfam PF06804 NlpB/DapX lipoprotein 40 343 5.9E-104 T 29-03-2018 IPR010653 NlpB/DapX lipoprotein MC49_RS16250 08c80c5622eb9d4919a6b6ee14a2de70 196 Gene3D G3DSA:3.40.630.30 9 177 3.0E-33 T 29-03-2018 MC49_RS16250 08c80c5622eb9d4919a6b6ee14a2de70 196 Pfam PF13302 Acetyltransferase (GNAT) domain 11 144 4.8E-21 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MC49_RS16250 08c80c5622eb9d4919a6b6ee14a2de70 196 SUPERFAMILY SSF55729 10 167 1.95E-39 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS03075 6a3c96301ca64830bb9a4335dd0c7240 737 Gene3D G3DSA:2.40.170.20 156 737 1.6E-51 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MC49_RS03075 6a3c96301ca64830bb9a4335dd0c7240 737 Pfam PF00593 TonB dependent receptor 279 732 1.4E-26 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MC49_RS03075 6a3c96301ca64830bb9a4335dd0c7240 737 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 46 737 1.1E-119 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 MC49_RS03075 6a3c96301ca64830bb9a4335dd0c7240 737 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 720 737 - T 29-03-2018 IPR010917 TonB-dependent receptor, conserved site MC49_RS03075 6a3c96301ca64830bb9a4335dd0c7240 737 Gene3D G3DSA:2.170.130.10 21 154 5.1E-27 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MC49_RS03075 6a3c96301ca64830bb9a4335dd0c7240 737 Pfam PF07715 TonB-dependent Receptor Plug Domain 45 146 7.3E-17 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MC49_RS03075 6a3c96301ca64830bb9a4335dd0c7240 737 SUPERFAMILY SSF56935 31 440 4.4E-92 T 29-03-2018 MC49_RS03075 6a3c96301ca64830bb9a4335dd0c7240 737 SUPERFAMILY SSF56935 471 737 4.4E-92 T 29-03-2018 MC49_RS08660 05e7062754e21fad5b1916f0e3e5f68e 240 SUPERFAMILY SSF55811 17 156 2.49E-29 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MC49_RS08660 05e7062754e21fad5b1916f0e3e5f68e 240 Gene3D G3DSA:3.90.79.10 20 159 4.0E-36 T 29-03-2018 MC49_RS08660 05e7062754e21fad5b1916f0e3e5f68e 240 Pfam PF00293 NUDIX domain 21 141 1.8E-13 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MC49_RS08660 05e7062754e21fad5b1916f0e3e5f68e 240 SUPERFAMILY SSF46785 166 233 9.25E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS08660 05e7062754e21fad5b1916f0e3e5f68e 240 Gene3D G3DSA:1.10.10.10 160 236 3.0E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS06535 950e5228b8274f82df699122d1199c01 196 Gene3D G3DSA:1.20.1590.10 5 194 2.5E-75 T 29-03-2018 IPR023381 YP001051499.1-like domain MC49_RS06535 950e5228b8274f82df699122d1199c01 196 Pfam PF04222 Protein of unknown function (DUF416) 5 193 2.4E-81 T 29-03-2018 IPR007338 Protein of unknown function DUF416 MC49_RS05870 757b0b24d46f89e8ed1e9e8be4b076b9 268 TIGRFAM TIGR02223 ftsN: cell division protein FtsN 2 194 1.5E-33 T 29-03-2018 IPR011930 Cell division protein FtsN GO:0005515 MC49_RS05870 757b0b24d46f89e8ed1e9e8be4b076b9 268 Hamap MF_02039 Cell division protein FtsN [ftsN]. 33 268 31.382 T 29-03-2018 IPR011930 Cell division protein FtsN GO:0005515 MC49_RS05870 757b0b24d46f89e8ed1e9e8be4b076b9 268 Gene3D G3DSA:3.30.70.1070 191 266 9.8E-17 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 MC49_RS05870 757b0b24d46f89e8ed1e9e8be4b076b9 268 Pfam PF05036 Sporulation related domain 194 262 5.3E-13 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 MC49_RS05870 757b0b24d46f89e8ed1e9e8be4b076b9 268 SUPERFAMILY SSF110997 195 264 1.83E-16 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 MC49_RS19150 12bd190170da5d8acc66db894ff82ec4 310 Gene3D G3DSA:3.40.1790.10 6 310 9.0E-143 T 29-03-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 MC49_RS19150 12bd190170da5d8acc66db894ff82ec4 310 Hamap MF_01876 Pseudouridine-5'-phosphate glycosidase [psuG]. 15 309 44.154 T 29-03-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 MC49_RS19150 12bd190170da5d8acc66db894ff82ec4 310 SUPERFAMILY SSF110581 9 307 1.96E-118 T 29-03-2018 MC49_RS19150 12bd190170da5d8acc66db894ff82ec4 310 Pfam PF04227 Indigoidine synthase A like protein 16 305 1.4E-135 T 29-03-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 MC49_RS12095 81d61a8c9bcab855123ce1e2ae0a7351 267 Gene3D G3DSA:3.40.190.80 146 267 8.3E-36 T 29-03-2018 MC49_RS12095 81d61a8c9bcab855123ce1e2ae0a7351 267 Gene3D G3DSA:3.30.540.10 1 145 4.4E-48 T 29-03-2018 MC49_RS12095 81d61a8c9bcab855123ce1e2ae0a7351 267 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 81 94 - T 29-03-2018 IPR020583 Inositol monophosphatase, metal-binding site MC49_RS12095 81d61a8c9bcab855123ce1e2ae0a7351 267 Pfam PF00459 Inositol monophosphatase family 2 261 5.0E-72 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MC49_RS12095 81d61a8c9bcab855123ce1e2ae0a7351 267 PRINTS PR01959 SuhB family inositol monophosphatase signature 17 39 3.6E-36 T 29-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 MC49_RS12095 81d61a8c9bcab855123ce1e2ae0a7351 267 PRINTS PR01959 SuhB family inositol monophosphatase signature 156 182 3.6E-36 T 29-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 MC49_RS12095 81d61a8c9bcab855123ce1e2ae0a7351 267 PRINTS PR01959 SuhB family inositol monophosphatase signature 198 210 3.6E-36 T 29-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 MC49_RS12095 81d61a8c9bcab855123ce1e2ae0a7351 267 PRINTS PR01959 SuhB family inositol monophosphatase signature 104 123 3.6E-36 T 29-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 MC49_RS12095 81d61a8c9bcab855123ce1e2ae0a7351 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 208 232 8.2E-58 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MC49_RS12095 81d61a8c9bcab855123ce1e2ae0a7351 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 38 58 8.2E-58 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MC49_RS12095 81d61a8c9bcab855123ce1e2ae0a7351 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 81 97 8.2E-58 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MC49_RS12095 81d61a8c9bcab855123ce1e2ae0a7351 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 130 153 8.2E-58 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MC49_RS12095 81d61a8c9bcab855123ce1e2ae0a7351 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 60 76 8.2E-58 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MC49_RS12095 81d61a8c9bcab855123ce1e2ae0a7351 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 177 198 8.2E-58 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MC49_RS12095 81d61a8c9bcab855123ce1e2ae0a7351 267 SUPERFAMILY SSF56655 1 259 1.96E-84 T 29-03-2018 MC49_RS18440 dea5699af235df4e545eb245cf0252ed 131 SUPERFAMILY SSF51230 3 127 1.96E-47 T 29-03-2018 IPR011053 Single hybrid motif MC49_RS18440 dea5699af235df4e545eb245cf0252ed 131 Gene3D G3DSA:2.40.50.100 6 131 1.8E-49 T 29-03-2018 MC49_RS18440 dea5699af235df4e545eb245cf0252ed 131 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 49 78 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MC49_RS18440 dea5699af235df4e545eb245cf0252ed 131 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 129 2.0E-54 T 29-03-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 MC49_RS18440 dea5699af235df4e545eb245cf0252ed 131 Pfam PF01597 Glycine cleavage H-protein 8 127 1.1E-47 T 29-03-2018 IPR033753 Glycine cleavage system H-protein/Simiate MC49_RS18440 dea5699af235df4e545eb245cf0252ed 131 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 5 127 40.629 T 29-03-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 MC49_RS01245 5b9b8864d499046c2e9020192153f75b 116 Pfam PF11171 Protein of unknown function (DUF2958) 5 115 8.5E-47 T 29-03-2018 IPR021341 Protein of unknown function DUF2958 MC49_RS05860 f8ae7018d93bcfb587f454253e99fc45 444 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 1 444 43.113 T 29-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 MC49_RS05860 f8ae7018d93bcfb587f454253e99fc45 444 SUPERFAMILY SSF52540 3 442 4.4E-93 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS05860 f8ae7018d93bcfb587f454253e99fc45 444 Gene3D G3DSA:1.10.8.10 121 200 2.0E-29 T 29-03-2018 MC49_RS05860 f8ae7018d93bcfb587f454253e99fc45 444 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 4 444 6.2E-229 T 29-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 MC49_RS05860 f8ae7018d93bcfb587f454253e99fc45 444 SMART SM01086 336 435 2.2E-21 T 29-03-2018 IPR019489 Clp ATPase, C-terminal MC49_RS05860 f8ae7018d93bcfb587f454253e99fc45 444 Gene3D G3DSA:1.10.8.60 336 432 2.8E-29 T 29-03-2018 MC49_RS05860 f8ae7018d93bcfb587f454253e99fc45 444 SMART SM00382 49 333 1.9E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS05860 f8ae7018d93bcfb587f454253e99fc45 444 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 53 107 6.1E-7 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MC49_RS05860 f8ae7018d93bcfb587f454253e99fc45 444 Gene3D G3DSA:1.10.8.10 201 243 3.5E-17 T 29-03-2018 MC49_RS05860 f8ae7018d93bcfb587f454253e99fc45 444 Gene3D G3DSA:3.40.50.300 11 120 6.6E-4 T 29-03-2018 MC49_RS05860 f8ae7018d93bcfb587f454253e99fc45 444 Pfam PF07724 AAA domain (Cdc48 subfamily) 189 330 8.3E-41 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MC49_RS05860 f8ae7018d93bcfb587f454253e99fc45 444 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 336 406 3.4E-5 T 29-03-2018 IPR019489 Clp ATPase, C-terminal MC49_RS05160 253652b85582fd611ea9126a92c998a2 177 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 137 156 - T 29-03-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05160 253652b85582fd611ea9126a92c998a2 177 Pfam PF00213 ATP synthase delta (OSCP) subunit 7 174 5.2E-49 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05160 253652b85582fd611ea9126a92c998a2 177 Gene3D G3DSA:1.10.520.20 2 106 1.6E-27 T 29-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05160 253652b85582fd611ea9126a92c998a2 177 Hamap MF_01416 ATP synthase subunit delta [atpD]. 3 177 18.19 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05160 253652b85582fd611ea9126a92c998a2 177 PRINTS PR00125 ATP synthase delta subunit signature 7 26 4.1E-26 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05160 253652b85582fd611ea9126a92c998a2 177 PRINTS PR00125 ATP synthase delta subunit signature 74 85 4.1E-26 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05160 253652b85582fd611ea9126a92c998a2 177 PRINTS PR00125 ATP synthase delta subunit signature 85 99 4.1E-26 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05160 253652b85582fd611ea9126a92c998a2 177 PRINTS PR00125 ATP synthase delta subunit signature 135 150 4.1E-26 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05160 253652b85582fd611ea9126a92c998a2 177 PRINTS PR00125 ATP synthase delta subunit signature 150 168 4.1E-26 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05160 253652b85582fd611ea9126a92c998a2 177 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 7 175 2.4E-58 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05160 253652b85582fd611ea9126a92c998a2 177 SUPERFAMILY SSF47928 3 105 3.79E-26 T 29-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS00430 676333881e79c3dad6f48c91b044c9ee 287 SUPERFAMILY SSF51735 123 280 2.0E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS00430 676333881e79c3dad6f48c91b044c9ee 287 Gene3D G3DSA:3.40.50.10860 11 140 1.0E-49 T 29-03-2018 MC49_RS00430 676333881e79c3dad6f48c91b044c9ee 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 155 175 1.4E-86 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 MC49_RS00430 676333881e79c3dad6f48c91b044c9ee 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 239 255 1.4E-86 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 MC49_RS00430 676333881e79c3dad6f48c91b044c9ee 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 256 274 1.4E-86 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 MC49_RS00430 676333881e79c3dad6f48c91b044c9ee 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 110 131 1.4E-86 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 MC49_RS00430 676333881e79c3dad6f48c91b044c9ee 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 204 233 1.4E-86 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 MC49_RS00430 676333881e79c3dad6f48c91b044c9ee 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 34 56 1.4E-86 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 MC49_RS00430 676333881e79c3dad6f48c91b044c9ee 287 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 75 102 1.4E-86 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 MC49_RS00430 676333881e79c3dad6f48c91b044c9ee 287 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 260 268 - T 29-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 MC49_RS00430 676333881e79c3dad6f48c91b044c9ee 287 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 124 281 1.3E-67 T 29-03-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 MC49_RS00430 676333881e79c3dad6f48c91b044c9ee 287 SUPERFAMILY SSF53223 1 122 8.92E-41 T 29-03-2018 MC49_RS00430 676333881e79c3dad6f48c91b044c9ee 287 Gene3D G3DSA:3.40.50.720 141 264 9.9E-39 T 29-03-2018 MC49_RS00430 676333881e79c3dad6f48c91b044c9ee 287 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 121 2.4E-39 T 29-03-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 MC49_RS00430 676333881e79c3dad6f48c91b044c9ee 287 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 283 37.399 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 MC49_RS00430 676333881e79c3dad6f48c91b044c9ee 287 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 76 101 - T 29-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 MC49_RS14255 b4621160e3a00ad462f67a60c3b9018f 364 Pfam PF13406 Transglycosylase SLT domain 64 357 6.8E-102 T 29-03-2018 IPR031304 Transglycosylase SLT domain 2 MC49_RS14255 b4621160e3a00ad462f67a60c3b9018f 364 TIGRFAM TIGR02283 MltB_2: lytic murein transglycosylase 63 359 1.5E-106 T 29-03-2018 IPR011970 Lytic murein transglycosylase MC49_RS14255 b4621160e3a00ad462f67a60c3b9018f 364 SUPERFAMILY SSF53955 59 358 2.53E-89 T 29-03-2018 IPR023346 Lysozyme-like domain MC49_RS14255 b4621160e3a00ad462f67a60c3b9018f 364 Gene3D G3DSA:1.10.8.350 127 233 1.7E-34 T 29-03-2018 MC49_RS14255 b4621160e3a00ad462f67a60c3b9018f 364 Gene3D G3DSA:1.10.530.10 238 364 1.4E-34 T 29-03-2018 MC49_RS17655 af69d4601e1b100dded26f780e61a262 237 TIGRFAM TIGR01641 phageSPP1_gp7: phage head morphogenesis protein, SPP1 gp7 family 120 231 6.1E-11 T 29-03-2018 IPR006528 Phage head morphogenesis domain MC49_RS17655 af69d4601e1b100dded26f780e61a262 237 Pfam PF04233 Phage Mu protein F like protein 120 225 6.6E-13 T 29-03-2018 IPR006528 Phage head morphogenesis domain MC49_RS08210 b83fec492275a36cbc6a5d4db6b1ff59 120 Gene3D G3DSA:3.30.479.10 1 120 8.0E-40 T 29-03-2018 MC49_RS08210 b83fec492275a36cbc6a5d4db6b1ff59 120 SUPERFAMILY SSF55620 2 119 6.12E-40 T 29-03-2018 MC49_RS08210 b83fec492275a36cbc6a5d4db6b1ff59 120 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 5 120 4.2E-34 T 29-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 MC49_RS08210 b83fec492275a36cbc6a5d4db6b1ff59 120 PIRSF PIRSF006113 1 120 7.0E-53 T 29-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 MC49_RS08210 b83fec492275a36cbc6a5d4db6b1ff59 120 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 5 95 2.8E-33 T 29-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 MC49_RS07505 1aca0a15d2807905845c5e2033cbcc88 306 SMART SM00871 126 302 1.9E-5 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding MC49_RS07505 1aca0a15d2807905845c5e2033cbcc88 306 SMART SM00342 21 104 1.9E-32 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MC49_RS07505 1aca0a15d2807905845c5e2033cbcc88 306 Pfam PF14526 Integron-associated effector binding protein 131 301 1.3E-14 T 29-03-2018 IPR029441 Integron-associated effector binding protein MC49_RS07505 1aca0a15d2807905845c5e2033cbcc88 306 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 73 88 3.7E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MC49_RS07505 1aca0a15d2807905845c5e2033cbcc88 306 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 88 104 3.7E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MC49_RS07505 1aca0a15d2807905845c5e2033cbcc88 306 SUPERFAMILY SSF46689 57 105 1.97E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS07505 1aca0a15d2807905845c5e2033cbcc88 306 SUPERFAMILY SSF55136 124 302 3.14E-27 T 29-03-2018 MC49_RS07505 1aca0a15d2807905845c5e2033cbcc88 306 SUPERFAMILY SSF46689 5 55 8.05E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS07505 1aca0a15d2807905845c5e2033cbcc88 306 Gene3D G3DSA:1.10.10.60 58 109 9.4E-12 T 29-03-2018 MC49_RS07505 1aca0a15d2807905845c5e2033cbcc88 306 Gene3D G3DSA:1.10.10.60 1 57 9.0E-15 T 29-03-2018 MC49_RS07505 1aca0a15d2807905845c5e2033cbcc88 306 Gene3D G3DSA:3.20.80.10 122 306 5.1E-26 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain MC49_RS07505 1aca0a15d2807905845c5e2033cbcc88 306 Pfam PF12833 Helix-turn-helix domain 27 105 1.3E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MC49_RS07505 1aca0a15d2807905845c5e2033cbcc88 306 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 55 100 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MC49_RS10220 5c7f36eb9da222194d4cd970649561b8 479 Pfam PF01938 TRAM domain 380 442 5.4E-20 T 29-03-2018 IPR002792 TRAM domain MC49_RS10220 5c7f36eb9da222194d4cd970649561b8 479 Pfam PF00919 Uncharacterized protein family UPF0004 6 106 3.4E-29 T 29-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 MC49_RS10220 5c7f36eb9da222194d4cd970649561b8 479 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 6 439 5.6E-156 T 29-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 MC49_RS10220 5c7f36eb9da222194d4cd970649561b8 479 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 153 173 - T 29-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 MC49_RS10220 5c7f36eb9da222194d4cd970649561b8 479 SUPERFAMILY SSF102114 129 374 9.29E-63 T 29-03-2018 MC49_RS10220 5c7f36eb9da222194d4cd970649561b8 479 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 5 442 73.657 T 29-03-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 MC49_RS10220 5c7f36eb9da222194d4cd970649561b8 479 Pfam PF04055 Radical SAM superfamily 153 327 2.9E-26 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MC49_RS10220 5c7f36eb9da222194d4cd970649561b8 479 SMART SM00729 149 369 3.8E-63 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MC49_RS10220 5c7f36eb9da222194d4cd970649561b8 479 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 6 442 2.6E-208 T 29-03-2018 MC49_RS10220 5c7f36eb9da222194d4cd970649561b8 479 Gene3D G3DSA:3.80.30.20 146 383 1.7E-52 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe MC49_RS06310 54d71cc7e9f30a85568e6ad000f7f978 303 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 8 297 9.1E-128 T 29-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 MC49_RS06310 54d71cc7e9f30a85568e6ad000f7f978 303 Gene3D G3DSA:1.10.8.10 245 270 7.2E-13 T 29-03-2018 MC49_RS06310 54d71cc7e9f30a85568e6ad000f7f978 303 Gene3D G3DSA:1.10.8.10 271 298 0.0011 T 29-03-2018 MC49_RS06310 54d71cc7e9f30a85568e6ad000f7f978 303 SUPERFAMILY SSF53697 8 251 5.93E-71 T 29-03-2018 MC49_RS06310 54d71cc7e9f30a85568e6ad000f7f978 303 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 4 297 42.793 T 29-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 MC49_RS06310 54d71cc7e9f30a85568e6ad000f7f978 303 Gene3D G3DSA:3.40.50.10490 13 244 9.3E-51 T 29-03-2018 MC49_RS06310 54d71cc7e9f30a85568e6ad000f7f978 303 Pfam PF13580 SIS domain 42 167 3.5E-7 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MC49_RS06310 54d71cc7e9f30a85568e6ad000f7f978 303 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 187 204 - T 29-03-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 MC49_RS07340 05afbe89cba5db6c573bb6b44dfa62be 928 SUPERFAMILY SSF63411 751 924 2.83E-15 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MC49_RS07340 05afbe89cba5db6c573bb6b44dfa62be 928 Gene3D G3DSA:3.30.830.10 16 253 2.8E-50 T 29-03-2018 MC49_RS07340 05afbe89cba5db6c573bb6b44dfa62be 928 Gene3D G3DSA:3.30.830.10 273 484 5.2E-14 T 29-03-2018 MC49_RS07340 05afbe89cba5db6c573bb6b44dfa62be 928 Gene3D G3DSA:3.30.830.10 500 724 7.7E-21 T 29-03-2018 MC49_RS07340 05afbe89cba5db6c573bb6b44dfa62be 928 Pfam PF00675 Insulinase (Peptidase family M16) 53 166 2.6E-25 T 29-03-2018 IPR011765 Peptidase M16, N-terminal MC49_RS07340 05afbe89cba5db6c573bb6b44dfa62be 928 Pfam PF05193 Peptidase M16 inactive domain 683 861 1.2E-14 T 29-03-2018 IPR007863 Peptidase M16, C-terminal MC49_RS07340 05afbe89cba5db6c573bb6b44dfa62be 928 Pfam PF05193 Peptidase M16 inactive domain 212 389 5.6E-12 T 29-03-2018 IPR007863 Peptidase M16, C-terminal MC49_RS07340 05afbe89cba5db6c573bb6b44dfa62be 928 Gene3D G3DSA:3.30.830.10 725 925 2.4E-19 T 29-03-2018 MC49_RS07340 05afbe89cba5db6c573bb6b44dfa62be 928 SUPERFAMILY SSF63411 517 730 8.1E-19 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MC49_RS07340 05afbe89cba5db6c573bb6b44dfa62be 928 SUPERFAMILY SSF63411 34 249 4.77E-43 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MC49_RS07340 05afbe89cba5db6c573bb6b44dfa62be 928 SUPERFAMILY SSF63411 361 465 2.33E-5 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MC49_RS12445 b9b7ec375ea277a8d56c741a07d01c3e 561 SMART SM00283 269 516 8.4E-86 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MC49_RS12445 b9b7ec375ea277a8d56c741a07d01c3e 561 SMART SM00304 216 268 7.4E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MC49_RS12445 b9b7ec375ea277a8d56c741a07d01c3e 561 SMART SM00319 44 182 3.3E-7 T 29-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 MC49_RS12445 b9b7ec375ea277a8d56c741a07d01c3e 561 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 327 484 1.3E-55 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MC49_RS12445 b9b7ec375ea277a8d56c741a07d01c3e 561 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 5 30 1.0E-76 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS12445 b9b7ec375ea277a8d56c741a07d01c3e 561 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 290 319 1.0E-76 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS12445 b9b7ec375ea277a8d56c741a07d01c3e 561 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 396 425 1.0E-76 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS12445 b9b7ec375ea277a8d56c741a07d01c3e 561 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 60 75 1.0E-76 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS12445 b9b7ec375ea277a8d56c741a07d01c3e 561 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 367 394 1.0E-76 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS12445 b9b7ec375ea277a8d56c741a07d01c3e 561 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 444 473 1.0E-76 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS12445 b9b7ec375ea277a8d56c741a07d01c3e 561 Gene3D G3DSA:1.10.287.950 186 319 1.9E-12 T 29-03-2018 MC49_RS12445 b9b7ec375ea277a8d56c741a07d01c3e 561 Pfam PF00672 HAMP domain 216 263 1.9E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MC49_RS12445 b9b7ec375ea277a8d56c741a07d01c3e 561 SUPERFAMILY SSF58104 236 518 2.22E-73 T 29-03-2018 MC49_RS12445 b9b7ec375ea277a8d56c741a07d01c3e 561 Gene3D G3DSA:1.10.287.950 320 520 1.2E-47 T 29-03-2018 MC49_RS12445 b9b7ec375ea277a8d56c741a07d01c3e 561 Pfam PF02203 Tar ligand binding domain homologue 1 170 2.5E-31 T 29-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 MC49_RS12445 b9b7ec375ea277a8d56c741a07d01c3e 561 Gene3D G3DSA:1.20.120.30 23 185 3.7E-25 T 29-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain MC49_RS12445 b9b7ec375ea277a8d56c741a07d01c3e 561 SUPERFAMILY SSF47170 25 176 2.62E-29 T 29-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 MC49_RS16410 44c73d67224e3f602ef273c01a47192f 58 Pfam PF10753 Toxin GhoT_OrtT 5 58 4.2E-24 T 29-03-2018 IPR019689 Toxin GhoT/OrtT MC49_RS11310 e022c77e1c76fc0256f047d83e1d24b3 360 SUPERFAMILY SSF103088 222 347 5.62E-34 T 29-03-2018 IPR006665 OmpA-like domain MC49_RS11310 e022c77e1c76fc0256f047d83e1d24b3 360 Pfam PF00691 OmpA family 235 326 6.8E-22 T 29-03-2018 IPR006665 OmpA-like domain MC49_RS11310 e022c77e1c76fc0256f047d83e1d24b3 360 Gene3D G3DSA:3.30.1330.60 220 360 5.4E-38 T 29-03-2018 IPR006665 OmpA-like domain MC49_RS11310 e022c77e1c76fc0256f047d83e1d24b3 360 SUPERFAMILY SSF56925 22 206 3.14E-38 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MC49_RS11310 e022c77e1c76fc0256f047d83e1d24b3 360 Pfam PF01389 OmpA-like transmembrane domain 23 207 6.3E-67 T 29-03-2018 IPR000498 Outer membrane protein OmpA-like, transmembrane domain GO:0009279|GO:0016021 MC49_RS11310 e022c77e1c76fc0256f047d83e1d24b3 360 PRINTS PR01022 Outer membrane protein A signature 191 205 1.0E-54 T 29-03-2018 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 MC49_RS11310 e022c77e1c76fc0256f047d83e1d24b3 360 PRINTS PR01022 Outer membrane protein A signature 326 339 1.0E-54 T 29-03-2018 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 MC49_RS11310 e022c77e1c76fc0256f047d83e1d24b3 360 PRINTS PR01022 Outer membrane protein A signature 116 132 1.0E-54 T 29-03-2018 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 MC49_RS11310 e022c77e1c76fc0256f047d83e1d24b3 360 PRINTS PR01022 Outer membrane protein A signature 177 191 1.0E-54 T 29-03-2018 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 MC49_RS11310 e022c77e1c76fc0256f047d83e1d24b3 360 PRINTS PR01022 Outer membrane protein A signature 253 272 1.0E-54 T 29-03-2018 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 MC49_RS11310 e022c77e1c76fc0256f047d83e1d24b3 360 PRINTS PR01022 Outer membrane protein A signature 292 311 1.0E-54 T 29-03-2018 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 MC49_RS11310 e022c77e1c76fc0256f047d83e1d24b3 360 PRINTS PR01022 Outer membrane protein A signature 224 239 1.0E-54 T 29-03-2018 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 MC49_RS11310 e022c77e1c76fc0256f047d83e1d24b3 360 Gene3D G3DSA:2.40.160.20 9 219 2.3E-44 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MC49_RS11310 e022c77e1c76fc0256f047d83e1d24b3 360 ProSitePatterns PS01068 OmpA-like domain. 270 314 - T 29-03-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 MC49_RS11310 e022c77e1c76fc0256f047d83e1d24b3 360 PRINTS PR01021 OMPA domain signature 283 299 5.2E-21 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MC49_RS11310 e022c77e1c76fc0256f047d83e1d24b3 360 PRINTS PR01021 OMPA domain signature 268 283 5.2E-21 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MC49_RS11310 e022c77e1c76fc0256f047d83e1d24b3 360 PRINTS PR01021 OMPA domain signature 236 258 5.2E-21 T 29-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MC49_RS08070 422367e53e1c2d4e4631b9fe2b41f929 798 Gene3D G3DSA:2.40.160.50 388 798 1.7E-86 T 29-03-2018 MC49_RS08070 422367e53e1c2d4e4631b9fe2b41f929 798 PIRSF PIRSF006076 1 798 2.3E-248 T 29-03-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 MC49_RS08070 422367e53e1c2d4e4631b9fe2b41f929 798 Gene3D G3DSA:3.10.20.310 92 173 1.7E-13 T 29-03-2018 MC49_RS08070 422367e53e1c2d4e4631b9fe2b41f929 798 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 24 798 7.1E-281 T 29-03-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 MC49_RS08070 422367e53e1c2d4e4631b9fe2b41f929 798 Gene3D G3DSA:3.10.20.310 266 346 9.0E-10 T 29-03-2018 MC49_RS08070 422367e53e1c2d4e4631b9fe2b41f929 798 Pfam PF01103 Surface antigen 448 798 2.2E-99 T 29-03-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 MC49_RS08070 422367e53e1c2d4e4631b9fe2b41f929 798 Gene3D G3DSA:3.10.20.310 21 91 8.8E-7 T 29-03-2018 MC49_RS08070 422367e53e1c2d4e4631b9fe2b41f929 798 Pfam PF07244 Surface antigen variable number repeat 266 344 8.8E-9 T 29-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 MC49_RS08070 422367e53e1c2d4e4631b9fe2b41f929 798 Pfam PF07244 Surface antigen variable number repeat 176 263 1.4E-15 T 29-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 MC49_RS08070 422367e53e1c2d4e4631b9fe2b41f929 798 Pfam PF07244 Surface antigen variable number repeat 348 421 8.3E-14 T 29-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 MC49_RS08070 422367e53e1c2d4e4631b9fe2b41f929 798 Pfam PF07244 Surface antigen variable number repeat 92 172 7.4E-11 T 29-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 MC49_RS08070 422367e53e1c2d4e4631b9fe2b41f929 798 Gene3D G3DSA:3.10.20.310 174 265 1.6E-20 T 29-03-2018 MC49_RS08070 422367e53e1c2d4e4631b9fe2b41f929 798 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 2 798 25.617 T 29-03-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 MC49_RS08070 422367e53e1c2d4e4631b9fe2b41f929 798 Gene3D G3DSA:3.10.20.310 350 387 0.039 T 29-03-2018 MC49_RS07330 e4f6f4f1f6a37334a7c19953a5be2efc 407 SUPERFAMILY SSF53649 237 407 1.7E-68 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MC49_RS07330 e4f6f4f1f6a37334a7c19953a5be2efc 407 SUPERFAMILY SSF53649 1 114 1.7E-68 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MC49_RS07330 e4f6f4f1f6a37334a7c19953a5be2efc 407 Hamap MF_00740 Phosphopentomutase [deoB]. 1 407 55.341 T 29-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 MC49_RS07330 e4f6f4f1f6a37334a7c19953a5be2efc 407 Gene3D G3DSA:3.30.70.1250 116 235 4.0E-51 T 29-03-2018 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 MC49_RS07330 e4f6f4f1f6a37334a7c19953a5be2efc 407 SUPERFAMILY SSF143856 117 235 1.57E-49 T 29-03-2018 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 MC49_RS07330 e4f6f4f1f6a37334a7c19953a5be2efc 407 PIRSF PIRSF001491 1 407 3.9E-164 T 29-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 MC49_RS07330 e4f6f4f1f6a37334a7c19953a5be2efc 407 Gene3D G3DSA:3.40.720.10 265 362 1.7E-4 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 MC49_RS07330 e4f6f4f1f6a37334a7c19953a5be2efc 407 TIGRFAM TIGR01696 deoB: phosphopentomutase 3 404 1.1E-189 T 29-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 MC49_RS07330 e4f6f4f1f6a37334a7c19953a5be2efc 407 Pfam PF01676 Metalloenzyme superfamily 2 398 2.2E-43 T 29-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 MC49_RS00890 c2b4e331cfe7b1d3b2c535eaa8d0eade 374 Gene3D G3DSA:3.20.20.105 1 368 2.0E-161 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MC49_RS00890 c2b4e331cfe7b1d3b2c535eaa8d0eade 374 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 1 364 58.067 T 29-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MC49_RS00890 c2b4e331cfe7b1d3b2c535eaa8d0eade 374 SUPERFAMILY SSF51713 2 364 1.02E-165 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MC49_RS00890 c2b4e331cfe7b1d3b2c535eaa8d0eade 374 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 3 367 1.4E-181 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MC49_RS00890 c2b4e331cfe7b1d3b2c535eaa8d0eade 374 Pfam PF01702 Queuine tRNA-ribosyltransferase 126 361 5.8E-95 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MC49_RS00890 c2b4e331cfe7b1d3b2c535eaa8d0eade 374 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 3 368 1.1E-191 T 29-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MC49_RS18810 9e23804924391175524117426e435f4e 307 Gene3D G3DSA:3.40.190.10 89 178 5.2E-10 T 29-03-2018 MC49_RS18810 9e23804924391175524117426e435f4e 307 Pfam PF03466 LysR substrate binding domain 89 296 2.8E-34 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS18810 9e23804924391175524117426e435f4e 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 9.3E-15 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS18810 9e23804924391175524117426e435f4e 307 SUPERFAMILY SSF53850 91 300 1.1E-35 T 29-03-2018 MC49_RS18810 9e23804924391175524117426e435f4e 307 Gene3D G3DSA:3.40.190.10 179 267 2.1E-19 T 29-03-2018 MC49_RS18810 9e23804924391175524117426e435f4e 307 SUPERFAMILY SSF46785 4 88 1.02E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS18810 9e23804924391175524117426e435f4e 307 Gene3D G3DSA:1.10.10.10 1 85 2.2E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS06600 6fec0f281939b442664a8b6e1ee94d71 621 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 164 174 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MC49_RS06600 6fec0f281939b442664a8b6e1ee94d71 621 SUPERFAMILY SSF143975 12 428 7.19E-142 T 29-03-2018 MC49_RS06600 6fec0f281939b442664a8b6e1ee94d71 621 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 515 526 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MC49_RS06600 6fec0f281939b442664a8b6e1ee94d71 621 TIGRFAM TIGR01196 edd: phosphogluconate dehydratase 12 611 0.0 T 29-03-2018 IPR004786 6-phosphogluconate dehydratase GO:0004456|GO:0009255 KEGG: 00030+4.2.1.12 MC49_RS06600 6fec0f281939b442664a8b6e1ee94d71 621 SUPERFAMILY SSF52016 429 611 5.34E-56 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel MC49_RS06600 6fec0f281939b442664a8b6e1ee94d71 621 Pfam PF00920 Dehydratase family 78 608 4.1E-155 T 29-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MC49_RS04550 408caf4db870b2b869b4689c7f37da71 488 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 218 464 1.4E-92 T 29-03-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 MC49_RS04550 408caf4db870b2b869b4689c7f37da71 488 SUPERFAMILY SSF48179 284 487 4.76E-65 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MC49_RS04550 408caf4db870b2b869b4689c7f37da71 488 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 219 231 - T 29-03-2018 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 MC49_RS04550 408caf4db870b2b869b4689c7f37da71 488 SUPERFAMILY SSF51735 9 282 3.42E-95 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS04550 408caf4db870b2b869b4689c7f37da71 488 Gene3D G3DSA:3.40.50.720 1 282 5.8E-105 T 29-03-2018 MC49_RS04550 408caf4db870b2b869b4689c7f37da71 488 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 25 189 1.4E-49 T 29-03-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 MC49_RS04550 408caf4db870b2b869b4689c7f37da71 488 Gene3D G3DSA:1.10.1040.10 283 488 1.3E-67 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MC49_RS04550 408caf4db870b2b869b4689c7f37da71 488 PRINTS PR00084 Mannitol dehydrogenase signature 180 193 3.5E-20 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 MC49_RS04550 408caf4db870b2b869b4689c7f37da71 488 PRINTS PR00084 Mannitol dehydrogenase signature 219 232 3.5E-20 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 MC49_RS04550 408caf4db870b2b869b4689c7f37da71 488 PRINTS PR00084 Mannitol dehydrogenase signature 249 264 3.5E-20 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 MC49_RS04550 408caf4db870b2b869b4689c7f37da71 488 PRINTS PR00084 Mannitol dehydrogenase signature 26 36 3.5E-20 T 29-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 MC49_RS06625 32f59837f427f3239e43c3937941c164 548 Pfam PF00342 Phosphoglucose isomerase 52 541 1.4E-251 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS06625 32f59837f427f3239e43c3937941c164 548 Gene3D G3DSA:3.40.50.10490 137 258 2.9E-53 T 29-03-2018 MC49_RS06625 32f59837f427f3239e43c3937941c164 548 Gene3D G3DSA:3.40.50.10490 7 136 1.6E-44 T 29-03-2018 MC49_RS06625 32f59837f427f3239e43c3937941c164 548 PRINTS PR00662 Glucose-6-phosphate isomerase signature 338 359 3.7E-56 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS06625 32f59837f427f3239e43c3937941c164 548 PRINTS PR00662 Glucose-6-phosphate isomerase signature 497 510 3.7E-56 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS06625 32f59837f427f3239e43c3937941c164 548 PRINTS PR00662 Glucose-6-phosphate isomerase signature 483 497 3.7E-56 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS06625 32f59837f427f3239e43c3937941c164 548 PRINTS PR00662 Glucose-6-phosphate isomerase signature 150 169 3.7E-56 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS06625 32f59837f427f3239e43c3937941c164 548 PRINTS PR00662 Glucose-6-phosphate isomerase signature 465 483 3.7E-56 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS06625 32f59837f427f3239e43c3937941c164 548 PRINTS PR00662 Glucose-6-phosphate isomerase signature 261 279 3.7E-56 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS06625 32f59837f427f3239e43c3937941c164 548 Gene3D G3DSA:1.10.1390.10 513 548 8.7E-21 T 29-03-2018 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS06625 32f59837f427f3239e43c3937941c164 548 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 497 514 - T 29-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS06625 32f59837f427f3239e43c3937941c164 548 Gene3D G3DSA:3.40.50.10490 259 512 3.6E-125 T 29-03-2018 MC49_RS06625 32f59837f427f3239e43c3937941c164 548 SUPERFAMILY SSF53697 5 547 4.45E-226 T 29-03-2018 MC49_RS06625 32f59837f427f3239e43c3937941c164 548 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 46 524 42.549 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS06625 32f59837f427f3239e43c3937941c164 548 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 265 278 - T 29-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS10030 9fe12ac14dd28f4b579f6f750c0383a6 379 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 186 343 3.3E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS10030 9fe12ac14dd28f4b579f6f750c0383a6 379 SUPERFAMILY SSF161098 165 347 7.98E-43 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS10030 9fe12ac14dd28f4b579f6f750c0383a6 379 Gene3D G3DSA:1.10.3720.10 115 359 6.1E-38 T 29-03-2018 MC49_RS02530 baaae5646f647af9297b7e396bcc389c 355 Gene3D G3DSA:2.60.40.1090 192 355 7.8E-14 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS02530 baaae5646f647af9297b7e396bcc389c 355 Pfam PF00419 Fimbrial protein 197 354 1.9E-11 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS02530 baaae5646f647af9297b7e396bcc389c 355 SUPERFAMILY SSF49401 201 354 1.84E-13 T 29-03-2018 IPR008966 Adhesion domain MC49_RS13495 65911586b6c6d4406952d855ae797e53 185 SMART SM00530 15 70 1.5E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS13495 65911586b6c6d4406952d855ae797e53 185 Gene3D G3DSA:2.60.120.10 76 184 2.5E-11 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MC49_RS13495 65911586b6c6d4406952d855ae797e53 185 Pfam PF01381 Helix-turn-helix 18 68 6.3E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS13495 65911586b6c6d4406952d855ae797e53 185 Gene3D G3DSA:1.10.260.40 10 75 2.4E-13 T 29-03-2018 MC49_RS13495 65911586b6c6d4406952d855ae797e53 185 SUPERFAMILY SSF51182 55 183 1.27E-16 T 29-03-2018 IPR011051 RmlC-like cupin domain MC49_RS13495 65911586b6c6d4406952d855ae797e53 185 SUPERFAMILY SSF47413 10 74 2.22E-13 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS10975 d667e7702ba2ac33045d44c2e10152aa 374 TIGRFAM TIGR02085 meth_trns_rumB: 23S rRNA (uracil-5-)-methyltransferase RumB 2 373 3.6E-190 T 29-03-2018 IPR011825 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC GO:0016070|GO:0016436 MC49_RS10975 d667e7702ba2ac33045d44c2e10152aa 374 Hamap MF_01012 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC [rlmC]. 1 374 79.044 T 29-03-2018 IPR011825 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC GO:0016070|GO:0016436 MC49_RS10975 d667e7702ba2ac33045d44c2e10152aa 374 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 306 337 - T 29-03-2018 IPR030390 RNA methyltransferase TrmA, active site MC49_RS10975 d667e7702ba2ac33045d44c2e10152aa 374 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 21 374 8.4E-19 T 29-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 MC49_RS10975 d667e7702ba2ac33045d44c2e10152aa 374 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 3 366 7.8E-56 T 29-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 MC49_RS10975 d667e7702ba2ac33045d44c2e10152aa 374 Gene3D G3DSA:3.40.50.150 1 372 1.8E-44 T 29-03-2018 MC49_RS10975 d667e7702ba2ac33045d44c2e10152aa 374 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 356 366 - T 29-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site MC49_RS10975 d667e7702ba2ac33045d44c2e10152aa 374 SUPERFAMILY SSF53335 3 373 7.86E-53 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS07905 54e18698e055d9942742cfa44fee9f8f 442 Pfam PF00583 Acetyltransferase (GNAT) family 335 412 1.1E-8 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MC49_RS07905 54e18698e055d9942742cfa44fee9f8f 442 Gene3D G3DSA:3.40.1160.10 6 293 2.0E-55 T 29-03-2018 MC49_RS07905 54e18698e055d9942742cfa44fee9f8f 442 SUPERFAMILY SSF55729 296 419 7.5E-18 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS07905 54e18698e055d9942742cfa44fee9f8f 442 PIRSF PIRSF000423 1 441 8.8E-206 T 29-03-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 MC49_RS07905 54e18698e055d9942742cfa44fee9f8f 442 Gene3D G3DSA:3.40.630.30 296 440 5.1E-20 T 29-03-2018 MC49_RS07905 54e18698e055d9942742cfa44fee9f8f 442 TIGRFAM TIGR01890 N-Ac-Glu-synth: amino-acid N-acetyltransferase 8 438 7.1E-193 T 29-03-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 MC49_RS07905 54e18698e055d9942742cfa44fee9f8f 442 SUPERFAMILY SSF53633 3 290 9.43E-70 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MC49_RS07905 54e18698e055d9942742cfa44fee9f8f 442 Pfam PF00696 Amino acid kinase family 25 266 1.6E-28 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MC49_RS07905 54e18698e055d9942742cfa44fee9f8f 442 Hamap MF_01105 Amino-acid acetyltransferase [argA]. 1 441 230.483 T 29-03-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 MC49_RS18995 87f744c70c220d6b383445d9f421cb4b 357 Pfam PF13437 HlyD family secretion protein 216 321 6.8E-10 T 29-03-2018 MC49_RS18995 87f744c70c220d6b383445d9f421cb4b 357 SUPERFAMILY SSF111369 42 122 4.18E-10 T 29-03-2018 MC49_RS18995 87f744c70c220d6b383445d9f421cb4b 357 Gene3D G3DSA:2.40.50.100 194 244 9.1E-4 T 29-03-2018 MC49_RS18995 87f744c70c220d6b383445d9f421cb4b 357 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 329 344 2.7E-5 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MC49_RS18995 87f744c70c220d6b383445d9f421cb4b 357 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 60 80 2.7E-5 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MC49_RS18995 87f744c70c220d6b383445d9f421cb4b 357 Pfam PF13533 Biotin-lipoyl like 50 95 8.3E-14 T 29-03-2018 MC49_RS18995 87f744c70c220d6b383445d9f421cb4b 357 Gene3D G3DSA:2.40.50.100 48 117 5.4E-17 T 29-03-2018 MC49_RS18995 87f744c70c220d6b383445d9f421cb4b 357 Gene3D G3DSA:1.10.287.470 118 177 9.1E-10 T 29-03-2018 MC49_RS18995 87f744c70c220d6b383445d9f421cb4b 357 SUPERFAMILY SSF111369 118 178 8.24E-6 T 29-03-2018 MC49_RS04010 b39443d56242dc45f7b7a5795beaa87c 458 SUPERFAMILY SSF51735 232 376 4.38E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS04010 b39443d56242dc45f7b7a5795beaa87c 458 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 1.4E-33 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MC49_RS04010 b39443d56242dc45f7b7a5795beaa87c 458 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 1.4E-33 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MC49_RS04010 b39443d56242dc45f7b7a5795beaa87c 458 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 1.4E-33 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MC49_RS04010 b39443d56242dc45f7b7a5795beaa87c 458 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 1.4E-33 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MC49_RS04010 b39443d56242dc45f7b7a5795beaa87c 458 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 1.4E-33 T 29-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MC49_RS04010 b39443d56242dc45f7b7a5795beaa87c 458 Gene3D G3DSA:3.40.50.720 248 366 2.5E-20 T 29-03-2018 MC49_RS04010 b39443d56242dc45f7b7a5795beaa87c 458 Gene3D G3DSA:3.40.50.720 1 140 1.2E-27 T 29-03-2018 MC49_RS04010 b39443d56242dc45f7b7a5795beaa87c 458 SUPERFAMILY SSF116726 390 451 6.93E-8 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MC49_RS04010 b39443d56242dc45f7b7a5795beaa87c 458 Gene3D G3DSA:3.50.50.60 218 247 0.24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS04010 b39443d56242dc45f7b7a5795beaa87c 458 SUPERFAMILY SSF51735 1 152 7.07E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS04010 b39443d56242dc45f7b7a5795beaa87c 458 SUPERFAMILY SSF116726 148 226 2.09E-10 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MC49_RS04010 b39443d56242dc45f7b7a5795beaa87c 458 Gene3D G3DSA:3.30.70.1450 141 217 9.0E-16 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MC49_RS04010 b39443d56242dc45f7b7a5795beaa87c 458 Pfam PF02254 TrkA-N domain 3 112 4.2E-31 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MC49_RS04010 b39443d56242dc45f7b7a5795beaa87c 458 Pfam PF02254 TrkA-N domain 235 350 6.3E-23 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MC49_RS04010 b39443d56242dc45f7b7a5795beaa87c 458 Gene3D G3DSA:3.30.70.1450 367 458 1.7E-15 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MC49_RS04010 b39443d56242dc45f7b7a5795beaa87c 458 Pfam PF02080 TrkA-C domain 391 451 4.0E-11 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MC49_RS04010 b39443d56242dc45f7b7a5795beaa87c 458 Pfam PF02080 TrkA-C domain 156 225 3.7E-11 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MC49_RS10350 155512ff60710d7d81bda1d09d53ae6e 431 Gene3D G3DSA:1.10.230.10 282 379 1.3E-36 T 29-03-2018 IPR016143 Citrate synthase-like, small alpha subdomain MC49_RS10350 155512ff60710d7d81bda1d09d53ae6e 431 SUPERFAMILY SSF48256 14 421 1.96E-165 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MC49_RS10350 155512ff60710d7d81bda1d09d53ae6e 431 Gene3D G3DSA:1.10.580.10 30 281 3.4E-89 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain MC49_RS10350 155512ff60710d7d81bda1d09d53ae6e 431 PIRSF PIRSF001369 38 428 4.7E-172 T 29-03-2018 IPR024176 Citrate synthase, bacterial-type MC49_RS10350 155512ff60710d7d81bda1d09d53ae6e 431 ProSitePatterns PS00480 Citrate synthase signature. 303 315 - T 29-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 MC49_RS10350 155512ff60710d7d81bda1d09d53ae6e 431 PRINTS PR00143 Citrate synthase signature 165 178 8.4E-56 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MC49_RS10350 155512ff60710d7d81bda1d09d53ae6e 431 PRINTS PR00143 Citrate synthase signature 219 234 8.4E-56 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MC49_RS10350 155512ff60710d7d81bda1d09d53ae6e 431 PRINTS PR00143 Citrate synthase signature 359 375 8.4E-56 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MC49_RS10350 155512ff60710d7d81bda1d09d53ae6e 431 PRINTS PR00143 Citrate synthase signature 296 316 8.4E-56 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MC49_RS10350 155512ff60710d7d81bda1d09d53ae6e 431 PRINTS PR00143 Citrate synthase signature 241 269 8.4E-56 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MC49_RS10350 155512ff60710d7d81bda1d09d53ae6e 431 PRINTS PR00143 Citrate synthase signature 379 393 8.4E-56 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MC49_RS10350 155512ff60710d7d81bda1d09d53ae6e 431 Pfam PF00285 Citrate synthase, C-terminal domain 46 410 1.1E-132 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MC49_RS10350 155512ff60710d7d81bda1d09d53ae6e 431 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 16 419 1.0E-234 T 29-03-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 MC49_RS12710 bc9d720d281c4295e5b51f8f71d077f4 240 SUPERFAMILY SSF88659 162 238 1.85E-20 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS12710 bc9d720d281c4295e5b51f8f71d077f4 240 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 15 236 2.6E-33 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS12710 bc9d720d281c4295e5b51f8f71d077f4 240 Gene3D G3DSA:1.10.1740.10 3 85 1.7E-20 T 29-03-2018 MC49_RS12710 bc9d720d281c4295e5b51f8f71d077f4 240 Gene3D G3DSA:1.10.10.10 90 137 3.5E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS12710 bc9d720d281c4295e5b51f8f71d077f4 240 Hamap MF_00962 RNA polymerase sigma factor FliA [fliA]. 5 239 61.075 T 29-03-2018 IPR028617 RNA polymerase sigma factor FliA GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 MC49_RS12710 bc9d720d281c4295e5b51f8f71d077f4 240 SUPERFAMILY SSF88659 90 152 1.61E-13 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS12710 bc9d720d281c4295e5b51f8f71d077f4 240 Pfam PF04542 Sigma-70 region 2 16 88 4.0E-16 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS12710 bc9d720d281c4295e5b51f8f71d077f4 240 Pfam PF04539 Sigma-70 region 3 97 166 1.8E-17 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS12710 bc9d720d281c4295e5b51f8f71d077f4 240 PRINTS PR00046 Major sigma-70 factor signature 221 232 1.2E-13 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS12710 bc9d720d281c4295e5b51f8f71d077f4 240 PRINTS PR00046 Major sigma-70 factor signature 67 75 1.2E-13 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS12710 bc9d720d281c4295e5b51f8f71d077f4 240 PRINTS PR00046 Major sigma-70 factor signature 43 56 1.2E-13 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS12710 bc9d720d281c4295e5b51f8f71d077f4 240 PRINTS PR00046 Major sigma-70 factor signature 189 201 1.2E-13 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS12710 bc9d720d281c4295e5b51f8f71d077f4 240 PRINTS PR00046 Major sigma-70 factor signature 206 221 1.2E-13 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS12710 bc9d720d281c4295e5b51f8f71d077f4 240 Pfam PF04545 Sigma-70, region 4 185 234 3.8E-17 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS12710 bc9d720d281c4295e5b51f8f71d077f4 240 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 43 56 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS12710 bc9d720d281c4295e5b51f8f71d077f4 240 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 16 237 7.7E-85 T 29-03-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 MC49_RS12710 bc9d720d281c4295e5b51f8f71d077f4 240 SUPERFAMILY SSF88946 5 88 1.57E-23 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS12710 bc9d720d281c4295e5b51f8f71d077f4 240 Gene3D G3DSA:1.10.10.10 172 240 3.1E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS12710 bc9d720d281c4295e5b51f8f71d077f4 240 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 206 232 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS12710 bc9d720d281c4295e5b51f8f71d077f4 240 PIRSF PIRSF000770 4 240 1.4E-40 T 29-03-2018 MC49_RS07230 96d01c1b048e517b6a066f6ff1c9ab14 208 Gene3D G3DSA:3.40.50.300 1 201 8.7E-36 T 29-03-2018 MC49_RS07230 96d01c1b048e517b6a066f6ff1c9ab14 208 Pfam PF00005 ABC transporter 18 150 3.3E-15 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS07230 96d01c1b048e517b6a066f6ff1c9ab14 208 SUPERFAMILY SSF52540 2 194 1.62E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS07230 96d01c1b048e517b6a066f6ff1c9ab14 208 ProSitePatterns PS00211 ABC transporters family signature. 122 136 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS07230 96d01c1b048e517b6a066f6ff1c9ab14 208 SMART SM00382 26 199 3.4E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS16610 f3b6c8b9010589db0078f84f7121ca4c 168 Pfam PF02674 Colicin V production protein 4 143 9.9E-38 T 29-03-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 MC49_RS17280 f22d91e74958ae868eb1da59d3628719 586 SUPERFAMILY SSF52540 237 364 3.66E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS17280 f22d91e74958ae868eb1da59d3628719 586 SUPERFAMILY SSF52540 50 169 3.66E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS17280 f22d91e74958ae868eb1da59d3628719 586 SMART SM00487 1 180 5.8E-17 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MC49_RS17280 f22d91e74958ae868eb1da59d3628719 586 Pfam PF00271 Helicase conserved C-terminal domain 242 343 2.4E-12 T 29-03-2018 IPR001650 Helicase, C-terminal MC49_RS17280 f22d91e74958ae868eb1da59d3628719 586 SMART SM00490 263 345 1.8E-10 T 29-03-2018 IPR001650 Helicase, C-terminal MC49_RS17280 f22d91e74958ae868eb1da59d3628719 586 Pfam PF04851 Type III restriction enzyme, res subunit 3 155 8.9E-26 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MC49_RS17280 f22d91e74958ae868eb1da59d3628719 586 Gene3D G3DSA:3.40.50.300 223 359 3.4E-19 T 29-03-2018 MC49_RS17280 f22d91e74958ae868eb1da59d3628719 586 Gene3D G3DSA:3.40.50.300 1 164 4.0E-30 T 29-03-2018 MC49_RS18190 e76b71e6a8005a32d35a47cde8b5a090 149 SUPERFAMILY SSF51197 3 141 4.67E-14 T 29-03-2018 MC49_RS18190 e76b71e6a8005a32d35a47cde8b5a090 149 Gene3D G3DSA:2.60.120.370 1 142 1.8E-17 T 29-03-2018 IPR004375 YhcH/YjgK/YiaL family MC49_RS18190 e76b71e6a8005a32d35a47cde8b5a090 149 Pfam PF04074 Domain of unknown function (DUF386) 3 139 4.4E-18 T 29-03-2018 IPR004375 YhcH/YjgK/YiaL family MC49_RS08730 1bfdacdf428ce77faef2a28febdebda8 404 Pfam PF00924 Mechanosensitive ion channel 136 380 1.9E-37 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MC49_RS08730 1bfdacdf428ce77faef2a28febdebda8 404 Gene3D G3DSA:2.30.30.60 195 245 9.8E-9 T 29-03-2018 MC49_RS08730 1bfdacdf428ce77faef2a28febdebda8 404 SUPERFAMILY SSF50182 179 245 1.86E-8 T 29-03-2018 IPR010920 LSM domain MC49_RS16535 7f03b051d1c65b521f610b19f9febefa 146 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 7 124 19.523 T 29-03-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 MC49_RS16535 7f03b051d1c65b521f610b19f9febefa 146 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 27 123 7.8E-31 T 29-03-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16600 1e7b643a2a9a28d5277768d9bc76c5eb 197 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 3 186 1.0E-67 T 29-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 MC49_RS16600 1e7b643a2a9a28d5277768d9bc76c5eb 197 Gene3D G3DSA:3.40.50.1950 2 196 1.1E-50 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 MC49_RS16600 1e7b643a2a9a28d5277768d9bc76c5eb 197 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 2 188 35.895 T 29-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 MC49_RS16600 1e7b643a2a9a28d5277768d9bc76c5eb 197 SUPERFAMILY SSF52507 2 186 6.54E-57 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 MC49_RS16600 1e7b643a2a9a28d5277768d9bc76c5eb 197 Pfam PF02441 Flavoprotein 2 165 1.0E-23 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 MC49_RS11435 ad1e2692e91f66f4c31f3c1684664fb9 233 SUPERFAMILY SSF49584 142 227 1.96E-19 T 29-03-2018 IPR016148 Pili assembly chaperone, C-terminal MC49_RS11435 ad1e2692e91f66f4c31f3c1684664fb9 233 Gene3D G3DSA:2.60.40.10 150 231 5.0E-20 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS11435 ad1e2692e91f66f4c31f3c1684664fb9 233 Gene3D G3DSA:2.60.40.10 29 149 8.4E-32 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS11435 ad1e2692e91f66f4c31f3c1684664fb9 233 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 170 225 1.6E-13 T 29-03-2018 IPR016148 Pili assembly chaperone, C-terminal MC49_RS11435 ad1e2692e91f66f4c31f3c1684664fb9 233 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 29 148 2.7E-38 T 29-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 MC49_RS11435 ad1e2692e91f66f4c31f3c1684664fb9 233 PRINTS PR00969 Pili chaperone signature 30 39 3.6E-32 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS11435 ad1e2692e91f66f4c31f3c1684664fb9 233 PRINTS PR00969 Pili chaperone signature 75 96 3.6E-32 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS11435 ad1e2692e91f66f4c31f3c1684664fb9 233 PRINTS PR00969 Pili chaperone signature 165 180 3.6E-32 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS11435 ad1e2692e91f66f4c31f3c1684664fb9 233 PRINTS PR00969 Pili chaperone signature 103 120 3.6E-32 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS11435 ad1e2692e91f66f4c31f3c1684664fb9 233 PRINTS PR00969 Pili chaperone signature 130 145 3.6E-32 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS11435 ad1e2692e91f66f4c31f3c1684664fb9 233 SUPERFAMILY SSF49354 29 148 1.96E-36 T 29-03-2018 IPR008962 PapD-like MC49_RS19125 2eea0ed677ff456847e68a65b570e526 523 TIGRFAM TIGR02004 PTS-IIBC-malX: PTS system, maltose and glucose-specific IIBC component 8 522 1.2E-222 T 29-03-2018 IPR011301 PTS system, maltose/glucose-specific IIBC component GO:0008982|GO:0009401 KEGG: 00230+2.7.1.20|KEGG: 00500+2.7.1.208|MetaCyc: PWY-6619 MC49_RS19125 2eea0ed677ff456847e68a65b570e526 523 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 462 479 - T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 MC49_RS19125 2eea0ed677ff456847e68a65b570e526 523 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 419 509 1.4E-20 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 MC49_RS19125 2eea0ed677ff456847e68a65b570e526 523 Pfam PF02378 Phosphotransferase system, EIIC 19 357 2.9E-68 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 MC49_RS19125 2eea0ed677ff456847e68a65b570e526 523 Pfam PF00367 phosphotransferase system, EIIB 453 484 1.2E-15 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 MC49_RS19125 2eea0ed677ff456847e68a65b570e526 523 Gene3D G3DSA:3.30.1360.60 449 523 4.6E-26 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 MC49_RS19125 2eea0ed677ff456847e68a65b570e526 523 SUPERFAMILY SSF55604 452 521 4.45E-20 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 MC49_RS07655 3eb0b84db73209e6f221d77eb72184ce 385 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 262 282 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 MC49_RS07655 3eb0b84db73209e6f221d77eb72184ce 385 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 373 7.4E-92 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 MC49_RS07655 3eb0b84db73209e6f221d77eb72184ce 385 Gene3D G3DSA:1.20.1090.10 182 385 1.6E-43 T 29-03-2018 MC49_RS07655 3eb0b84db73209e6f221d77eb72184ce 385 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 171 199 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 MC49_RS07655 3eb0b84db73209e6f221d77eb72184ce 385 SUPERFAMILY SSF56796 1 383 5.76E-111 T 29-03-2018 MC49_RS07655 3eb0b84db73209e6f221d77eb72184ce 385 Gene3D G3DSA:3.40.50.1970 9 181 4.3E-45 T 29-03-2018 MC49_RS00170 9223c3240c2232b8f7023e0d0ea2cda1 251 SMART SM00635 165 245 1.2E-16 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 MC49_RS00170 9223c3240c2232b8f7023e0d0ea2cda1 251 SUPERFAMILY SSF49373 162 248 1.02E-9 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS00170 9223c3240c2232b8f7023e0d0ea2cda1 251 Gene3D G3DSA:2.60.40.1080 161 251 4.6E-19 T 29-03-2018 MC49_RS00170 9223c3240c2232b8f7023e0d0ea2cda1 251 Pfam PF02368 Bacterial Ig-like domain (group 2) 166 246 7.5E-14 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 MC49_RS07395 015f7387dd3a8135918e8d8142e72cec 140 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 11 107 1.1E-41 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MC49_RS07395 015f7387dd3a8135918e8d8142e72cec 140 Gene3D G3DSA:2.10.150.10 26 140 2.6E-44 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MC49_RS07395 015f7387dd3a8135918e8d8142e72cec 140 Pfam PF00699 Urease beta subunit 11 106 1.5E-42 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MC49_RS07395 015f7387dd3a8135918e8d8142e72cec 140 SUPERFAMILY SSF51278 11 112 2.88E-44 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MC49_RS07395 015f7387dd3a8135918e8d8142e72cec 140 Hamap MF_01954 Urease subunit beta [ureB]. 8 108 29.805 T 29-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MC49_RS04790 5336a9e8c3d70b4e59481641f21a2799 446 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 202 444 1.3E-87 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MC49_RS04790 5336a9e8c3d70b4e59481641f21a2799 446 SUPERFAMILY SSF51735 202 445 1.34E-76 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS04790 5336a9e8c3d70b4e59481641f21a2799 446 Gene3D G3DSA:3.40.50.10860 65 190 2.4E-54 T 29-03-2018 MC49_RS04790 5336a9e8c3d70b4e59481641f21a2799 446 Gene3D G3DSA:3.40.50.720 209 372 4.0E-43 T 29-03-2018 MC49_RS04790 5336a9e8c3d70b4e59481641f21a2799 446 SUPERFAMILY SSF53223 6 196 3.2E-73 T 29-03-2018 MC49_RS04790 5336a9e8c3d70b4e59481641f21a2799 446 Gene3D G3DSA:1.10.285.10 373 446 1.1E-26 T 29-03-2018 MC49_RS04790 5336a9e8c3d70b4e59481641f21a2799 446 Gene3D G3DSA:1.10.285.10 6 64 1.3E-5 T 29-03-2018 MC49_RS04790 5336a9e8c3d70b4e59481641f21a2799 446 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 122 135 - T 29-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MC49_RS04790 5336a9e8c3d70b4e59481641f21a2799 446 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 57 184 1.3E-49 T 29-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MC49_RS04790 5336a9e8c3d70b4e59481641f21a2799 446 SMART SM00839 204 444 9.6E-95 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MC49_RS04790 5336a9e8c3d70b4e59481641f21a2799 446 PIRSF PIRSF000185 22 446 5.3E-112 T 29-03-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 MC49_RS04790 5336a9e8c3d70b4e59481641f21a2799 446 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 114 128 4.4E-32 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MC49_RS04790 5336a9e8c3d70b4e59481641f21a2799 446 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 371 382 4.4E-32 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MC49_RS04790 5336a9e8c3d70b4e59481641f21a2799 446 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 235 255 4.4E-32 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MC49_RS04790 5336a9e8c3d70b4e59481641f21a2799 446 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 193 215 4.4E-32 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MC49_RS04360 f1b9c4ca8f668a7bbd3298ead9fcc13f 346 Gene3D G3DSA:3.40.190.10 161 338 2.7E-28 T 29-03-2018 MC49_RS04360 f1b9c4ca8f668a7bbd3298ead9fcc13f 346 Gene3D G3DSA:3.40.190.10 26 160 4.6E-33 T 29-03-2018 MC49_RS04360 f1b9c4ca8f668a7bbd3298ead9fcc13f 346 SUPERFAMILY SSF53850 29 336 1.87E-96 T 29-03-2018 MC49_RS04360 f1b9c4ca8f668a7bbd3298ead9fcc13f 346 Pfam PF12849 PBP superfamily domain 25 307 1.7E-60 T 29-03-2018 IPR024370 PBP domain MC49_RS04360 f1b9c4ca8f668a7bbd3298ead9fcc13f 346 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 29 335 1.4E-127 T 29-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 MC49_RS04360 f1b9c4ca8f668a7bbd3298ead9fcc13f 346 PIRSF PIRSF002756 2 338 9.1E-108 T 29-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 MC49_RS19110 a3f2493997581cb1f9867947fb197239 379 Gene3D G3DSA:3.20.20.140 66 349 1.4E-92 T 29-03-2018 MC49_RS19110 a3f2493997581cb1f9867947fb197239 379 Pfam PF01979 Amidohydrolase family 47 378 1.5E-16 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MC49_RS19110 a3f2493997581cb1f9867947fb197239 379 SUPERFAMILY SSF51338 4 49 8.93E-9 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS19110 a3f2493997581cb1f9867947fb197239 379 SUPERFAMILY SSF51338 349 378 8.93E-9 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS19110 a3f2493997581cb1f9867947fb197239 379 SUPERFAMILY SSF51556 51 349 2.19E-89 T 29-03-2018 IPR032466 Metal-dependent hydrolase MC49_RS19110 a3f2493997581cb1f9867947fb197239 379 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 5 375 1.5E-83 T 29-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 MC49_RS19110 a3f2493997581cb1f9867947fb197239 379 Gene3D G3DSA:2.30.40.10 4 65 1.1E-7 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS19110 a3f2493997581cb1f9867947fb197239 379 PIRSF PIRSF038994 1 379 7.1E-112 T 29-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 MC49_RS09035 0261e061fc51f84997a9e7063a5f9727 300 Hamap MF_01428 Glutamyl-Q tRNA(Asp) synthetase [gluQ]. 12 297 39.292 T 29-03-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 MC49_RS09035 0261e061fc51f84997a9e7063a5f9727 300 Gene3D G3DSA:3.40.50.620 118 228 8.3E-22 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS09035 0261e061fc51f84997a9e7063a5f9727 300 Gene3D G3DSA:3.40.50.620 12 117 8.2E-33 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS09035 0261e061fc51f84997a9e7063a5f9727 300 TIGRFAM TIGR03838 queuosine_YadB: glutamyl-queuosine tRNA(Asp) synthetase 12 266 9.8E-103 T 29-03-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 MC49_RS09035 0261e061fc51f84997a9e7063a5f9727 300 SUPERFAMILY SSF52374 12 272 6.97E-79 T 29-03-2018 MC49_RS09035 0261e061fc51f84997a9e7063a5f9727 300 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 15 242 4.1E-41 T 29-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 MC49_RS09035 0261e061fc51f84997a9e7063a5f9727 300 PRINTS PR00987 Glutamyl-tRNA synthetase signature 15 27 5.7E-14 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 MC49_RS09035 0261e061fc51f84997a9e7063a5f9727 300 PRINTS PR00987 Glutamyl-tRNA synthetase signature 44 57 5.7E-14 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 MC49_RS09035 0261e061fc51f84997a9e7063a5f9727 300 PRINTS PR00987 Glutamyl-tRNA synthetase signature 176 186 5.7E-14 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 MC49_RS09035 0261e061fc51f84997a9e7063a5f9727 300 PRINTS PR00987 Glutamyl-tRNA synthetase signature 192 200 5.7E-14 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 MC49_RS09035 0261e061fc51f84997a9e7063a5f9727 300 PRINTS PR00987 Glutamyl-tRNA synthetase signature 29 40 5.7E-14 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 MC49_RS00290 6df3bc3c6fd3af3f7857544589e708cd 124 Gene3D G3DSA:2.30.130.30 1 107 7.3E-22 T 29-03-2018 MC49_RS00290 6df3bc3c6fd3af3f7857544589e708cd 124 Pfam PF04266 ASCH domain 4 84 5.8E-10 T 29-03-2018 IPR007374 ASCH domain MC49_RS00290 6df3bc3c6fd3af3f7857544589e708cd 124 SUPERFAMILY SSF88697 1 39 5.47E-19 T 29-03-2018 IPR015947 PUA-like domain MC49_RS00290 6df3bc3c6fd3af3f7857544589e708cd 124 SUPERFAMILY SSF88697 70 116 5.47E-19 T 29-03-2018 IPR015947 PUA-like domain MC49_RS08475 abef858e3694d40dc6e58a218f9c4612 242 SUPERFAMILY SSF75615 139 231 1.31E-12 T 29-03-2018 MC49_RS08475 abef858e3694d40dc6e58a218f9c4612 242 Gene3D G3DSA:3.30.160.110 131 169 5.3E-4 T 29-03-2018 MC49_RS08475 abef858e3694d40dc6e58a218f9c4612 242 Pfam PF10414 Sirohaem synthase dimerisation region 181 216 5.1E-5 T 29-03-2018 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 MC49_RS08475 abef858e3694d40dc6e58a218f9c4612 242 Pfam PF13241 Putative NAD(P)-binding 30 140 3.6E-26 T 29-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 MC49_RS08475 abef858e3694d40dc6e58a218f9c4612 242 Gene3D G3DSA:1.10.8.210 179 233 7.3E-8 T 29-03-2018 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 MC49_RS08475 abef858e3694d40dc6e58a218f9c4612 242 Gene3D G3DSA:3.40.50.720 25 130 5.6E-16 T 29-03-2018 MC49_RS08475 abef858e3694d40dc6e58a218f9c4612 242 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 28 223 4.7E-45 T 29-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 MC49_RS08475 abef858e3694d40dc6e58a218f9c4612 242 SUPERFAMILY SSF51735 27 137 2.07E-25 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS05275 c7f1d1a93a988a4e7f8000138923f303 369 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 262 276 - T 29-03-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 MC49_RS05275 c7f1d1a93a988a4e7f8000138923f303 369 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 144 354 5.3E-58 T 29-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MC49_RS05275 c7f1d1a93a988a4e7f8000138923f303 369 SMART SM00859 3 122 3.7E-25 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MC49_RS05275 c7f1d1a93a988a4e7f8000138923f303 369 TIGRFAM TIGR01745 asd_gamma: aspartate-semialdehyde dehydrogenase 2 368 7.3E-207 T 29-03-2018 IPR011534 Aspartate-semialdehyde dehydrogenase, gamma-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 MC49_RS05275 c7f1d1a93a988a4e7f8000138923f303 369 SUPERFAMILY SSF51735 1 147 1.36E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS05275 c7f1d1a93a988a4e7f8000138923f303 369 Gene3D G3DSA:3.40.50.720 1 144 3.7E-18 T 29-03-2018 MC49_RS05275 c7f1d1a93a988a4e7f8000138923f303 369 SUPERFAMILY SSF55347 134 355 3.12E-76 T 29-03-2018 MC49_RS05275 c7f1d1a93a988a4e7f8000138923f303 369 PIRSF PIRSF000148 1 369 5.5E-68 T 29-03-2018 MC49_RS05275 c7f1d1a93a988a4e7f8000138923f303 369 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 121 9.9E-24 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MC49_RS05275 c7f1d1a93a988a4e7f8000138923f303 369 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 1 368 34.049 T 29-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 MC49_RS05275 c7f1d1a93a988a4e7f8000138923f303 369 Gene3D G3DSA:3.30.360.10 145 351 1.3E-59 T 29-03-2018 MC49_RS02015 73c7ea638e487312ec34837e6be00a5c 163 SUPERFAMILY SSF53163 8 149 4.97E-30 T 29-03-2018 IPR023430 Peptidase HybD-like domain MC49_RS02015 73c7ea638e487312ec34837e6be00a5c 163 Gene3D G3DSA:3.40.50.1450 3 155 3.4E-30 T 29-03-2018 IPR023430 Peptidase HybD-like domain MC49_RS02015 73c7ea638e487312ec34837e6be00a5c 163 TIGRFAM TIGR00142 hycI: hydrogenase maturation peptidase HycI 9 149 7.0E-51 T 29-03-2018 IPR004420 Peptidase A31, hydrogenase maturation protease HycI GO:0008233 MC49_RS02015 73c7ea638e487312ec34837e6be00a5c 163 PRINTS PR00446 Hydrogen uptake protein signature 72 88 9.1E-8 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MC49_RS02015 73c7ea638e487312ec34837e6be00a5c 163 PRINTS PR00446 Hydrogen uptake protein signature 8 20 9.1E-8 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MC49_RS02015 73c7ea638e487312ec34837e6be00a5c 163 PRINTS PR00446 Hydrogen uptake protein signature 61 71 9.1E-8 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MC49_RS02015 73c7ea638e487312ec34837e6be00a5c 163 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 10 143 7.0E-31 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MC49_RS02015 73c7ea638e487312ec34837e6be00a5c 163 Pfam PF01750 Hydrogenase maturation protease 38 143 8.1E-22 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MC49_RS10550 83415c3a2c6a13abddebad6a630cf6de 355 Gene3D G3DSA:2.40.50.100 286 349 2.2E-20 T 29-03-2018 MC49_RS10550 83415c3a2c6a13abddebad6a630cf6de 355 TIGRFAM TIGR02142 modC_ABC: molybdate ABC transporter, ATP-binding protein 3 351 3.3E-144 T 29-03-2018 IPR011868 Molybdate ABC transporter, ATP-binding protein GO:0005524|GO:0015098|GO:0015689|GO:0016020 MC49_RS10550 83415c3a2c6a13abddebad6a630cf6de 355 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 290 350 1.0E-15 T 29-03-2018 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 MC49_RS10550 83415c3a2c6a13abddebad6a630cf6de 355 Pfam PF03459 TOBE domain 290 351 1.0E-17 T 29-03-2018 IPR005116 Transport-associated OB, type 1 MC49_RS10550 83415c3a2c6a13abddebad6a630cf6de 355 Pfam PF00005 ABC transporter 17 156 8.6E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS10550 83415c3a2c6a13abddebad6a630cf6de 355 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS10550 83415c3a2c6a13abddebad6a630cf6de 355 SUPERFAMILY SSF52540 16 221 2.44E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS10550 83415c3a2c6a13abddebad6a630cf6de 355 SMART SM00382 23 208 1.8E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS10550 83415c3a2c6a13abddebad6a630cf6de 355 SUPERFAMILY SSF50331 235 351 1.51E-20 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal MC49_RS10550 83415c3a2c6a13abddebad6a630cf6de 355 Gene3D G3DSA:3.40.50.300 15 285 2.2E-53 T 29-03-2018 MC49_RS03215 0a7f072b679e164a39c68777aa93b5e1 503 SUPERFAMILY SSF52949 1 184 2.59E-50 T 29-03-2018 MC49_RS03215 0a7f072b679e164a39c68777aa93b5e1 503 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 19 147 1.7E-32 T 29-03-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MC49_RS03215 0a7f072b679e164a39c68777aa93b5e1 503 SUPERFAMILY SSF53187 180 496 1.66E-124 T 29-03-2018 MC49_RS03215 0a7f072b679e164a39c68777aa93b5e1 503 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 350 357 - T 29-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MC49_RS03215 0a7f072b679e164a39c68777aa93b5e1 503 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 186 489 1.2E-121 T 29-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MC49_RS03215 0a7f072b679e164a39c68777aa93b5e1 503 Gene3D G3DSA:3.40.220.10 1 159 2.7E-28 T 29-03-2018 MC49_RS03215 0a7f072b679e164a39c68777aa93b5e1 503 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 3 498 40.559 T 29-03-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 MC49_RS03215 0a7f072b679e164a39c68777aa93b5e1 503 PRINTS PR00481 Cytosol aminopeptidase signature 324 345 1.9E-54 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MC49_RS03215 0a7f072b679e164a39c68777aa93b5e1 503 PRINTS PR00481 Cytosol aminopeptidase signature 374 389 1.9E-54 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MC49_RS03215 0a7f072b679e164a39c68777aa93b5e1 503 PRINTS PR00481 Cytosol aminopeptidase signature 287 308 1.9E-54 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MC49_RS03215 0a7f072b679e164a39c68777aa93b5e1 503 PRINTS PR00481 Cytosol aminopeptidase signature 346 366 1.9E-54 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MC49_RS03215 0a7f072b679e164a39c68777aa93b5e1 503 PRINTS PR00481 Cytosol aminopeptidase signature 265 282 1.9E-54 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MC49_RS03215 0a7f072b679e164a39c68777aa93b5e1 503 Gene3D G3DSA:3.40.630.10 170 501 6.1E-133 T 29-03-2018 MC49_RS05425 7df8cdf0c56df838b352dedb1afc85f9 313 TIGRFAM TIGR01582 FDH-beta: formate dehydrogenase, beta subunit 7 290 5.7E-144 T 29-03-2018 IPR006470 Formate dehydrogenase iron-sulphur subunit, Proteobacteria GO:0015944|GO:0016021|GO:0045333|GO:0051539 MC49_RS05425 7df8cdf0c56df838b352dedb1afc85f9 313 Gene3D G3DSA:3.30.70.20 113 156 5.6E-16 T 29-03-2018 MC49_RS05425 7df8cdf0c56df838b352dedb1afc85f9 313 Gene3D G3DSA:3.30.70.20 13 42 0.0052 T 29-03-2018 MC49_RS05425 7df8cdf0c56df838b352dedb1afc85f9 313 SUPERFAMILY SSF54862 27 270 1.47E-74 T 29-03-2018 MC49_RS05425 7df8cdf0c56df838b352dedb1afc85f9 313 PIRSF PIRSF036298 1 312 2.6E-163 T 29-03-2018 IPR014603 Formate dehydrogenase iron-sulphur subunit GO:0015944|GO:0045333|GO:0051539 MC49_RS05425 7df8cdf0c56df838b352dedb1afc85f9 313 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 133 144 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MC49_RS05425 7df8cdf0c56df838b352dedb1afc85f9 313 Gene3D G3DSA:3.30.70.20 157 194 3.7E-5 T 29-03-2018 MC49_RS05425 7df8cdf0c56df838b352dedb1afc85f9 313 Pfam PF09163 Formate dehydrogenase N, transmembrane 246 289 9.4E-21 T 29-03-2018 IPR015246 Formate dehydrogenase, transmembrane MC49_RS05425 7df8cdf0c56df838b352dedb1afc85f9 313 Pfam PF13247 4Fe-4S dicluster domain 92 188 2.1E-25 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MC49_RS05425 7df8cdf0c56df838b352dedb1afc85f9 313 Gene3D G3DSA:1.20.5.480 249 291 1.3E-21 T 29-03-2018 MC49_RS05425 7df8cdf0c56df838b352dedb1afc85f9 313 Gene3D G3DSA:3.30.70.20 43 112 3.4E-22 T 29-03-2018 MC49_RS18600 661b0a0c8b45052f57b5bd355e0e9f93 131 PRINTS PR01401 Mutator MutT protein signature 5 26 2.2E-13 T 29-03-2018 IPR003561 Mutator MutT GO:0006281|GO:0008413 MetaCyc: PWY-6502 MC49_RS18600 661b0a0c8b45052f57b5bd355e0e9f93 131 PRINTS PR01401 Mutator MutT protein signature 80 93 2.2E-13 T 29-03-2018 IPR003561 Mutator MutT GO:0006281|GO:0008413 MetaCyc: PWY-6502 MC49_RS18600 661b0a0c8b45052f57b5bd355e0e9f93 131 Pfam PF00293 NUDIX domain 8 126 2.9E-20 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MC49_RS18600 661b0a0c8b45052f57b5bd355e0e9f93 131 ProSitePatterns PS00893 Nudix box signature. 41 62 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MC49_RS18600 661b0a0c8b45052f57b5bd355e0e9f93 131 PRINTS PR00502 NUDIX hydrolase family signature 36 50 1.8E-9 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MC49_RS18600 661b0a0c8b45052f57b5bd355e0e9f93 131 PRINTS PR00502 NUDIX hydrolase family signature 50 65 1.8E-9 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MC49_RS18600 661b0a0c8b45052f57b5bd355e0e9f93 131 SUPERFAMILY SSF55811 2 129 8.26E-38 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MC49_RS18600 661b0a0c8b45052f57b5bd355e0e9f93 131 Gene3D G3DSA:3.90.79.10 5 131 1.2E-31 T 29-03-2018 MC49_RS18600 661b0a0c8b45052f57b5bd355e0e9f93 131 TIGRFAM TIGR00586 mutt: mutator mutT protein 4 129 8.2E-48 T 29-03-2018 IPR003561 Mutator MutT GO:0006281|GO:0008413 MetaCyc: PWY-6502 MC49_RS11695 cc276fc47baa81dcacf8bf66a46ad2e0 176 Gene3D G3DSA:1.20.1250.20 37 168 8.3E-5 T 29-03-2018 MC49_RS17180 d1d47118e3eba2fecddf881d8987fe9a 654 Gene3D G3DSA:2.170.130.10 20 162 4.8E-33 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MC49_RS17180 d1d47118e3eba2fecddf881d8987fe9a 654 Pfam PF00593 TonB dependent receptor 217 653 3.6E-57 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MC49_RS17180 d1d47118e3eba2fecddf881d8987fe9a 654 SUPERFAMILY SSF56935 31 654 1.6E-121 T 29-03-2018 MC49_RS17180 d1d47118e3eba2fecddf881d8987fe9a 654 Gene3D G3DSA:2.40.170.20 168 654 8.7E-74 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MC49_RS17180 d1d47118e3eba2fecddf881d8987fe9a 654 Pfam PF07715 TonB-dependent Receptor Plug Domain 46 155 1.5E-26 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MC49_RS14225 4c202cdd2b39e74f1a3c125b2aa62266 563 SUPERFAMILY SSF56801 17 553 3.27E-148 T 29-03-2018 MC49_RS14225 4c202cdd2b39e74f1a3c125b2aa62266 563 Gene3D G3DSA:3.40.50.980 20 216 4.9E-42 T 29-03-2018 MC49_RS14225 4c202cdd2b39e74f1a3c125b2aa62266 563 Gene3D G3DSA:2.30.38.10 372 453 5.3E-30 T 29-03-2018 MC49_RS14225 4c202cdd2b39e74f1a3c125b2aa62266 563 Gene3D G3DSA:3.30.300.30 454 559 1.6E-25 T 29-03-2018 MC49_RS14225 4c202cdd2b39e74f1a3c125b2aa62266 563 Pfam PF00501 AMP-binding enzyme 30 460 3.3E-110 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MC49_RS14225 4c202cdd2b39e74f1a3c125b2aa62266 563 Gene3D G3DSA:3.40.50.980 217 371 2.3E-37 T 29-03-2018 MC49_RS14225 4c202cdd2b39e74f1a3c125b2aa62266 563 ProSitePatterns PS00455 Putative AMP-binding domain signature. 211 222 - T 29-03-2018 IPR020845 AMP-binding, conserved site MC49_RS14225 4c202cdd2b39e74f1a3c125b2aa62266 563 Pfam PF13193 AMP-binding enzyme C-terminal domain 469 543 1.8E-17 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain MC49_RS15675 799421ad811b75141e24a1178847a282 144 Gene3D G3DSA:1.10.10.10 1 144 3.1E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS15675 799421ad811b75141e24a1178847a282 144 SUPERFAMILY SSF46785 4 139 1.48E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS15675 799421ad811b75141e24a1178847a282 144 Pfam PF01047 MarR family 29 87 8.7E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MC49_RS15675 799421ad811b75141e24a1178847a282 144 SMART SM00347 22 123 2.1E-23 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MC49_RS15675 799421ad811b75141e24a1178847a282 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 79 2.2E-24 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MC49_RS15675 799421ad811b75141e24a1178847a282 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 47 63 2.2E-24 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MC49_RS15675 799421ad811b75141e24a1178847a282 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 99 2.2E-24 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MC49_RS15675 799421ad811b75141e24a1178847a282 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 113 133 2.2E-24 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MC49_RS04530 dc18fd421cd5d1b5bd2014c6a8c2a371 606 SUPERFAMILY SSF47384 374 450 1.59E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS04530 dc18fd421cd5d1b5bd2014c6a8c2a371 606 Gene3D G3DSA:3.30.565.10 450 606 8.5E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS04530 dc18fd421cd5d1b5bd2014c6a8c2a371 606 SMART SM00091 259 326 1.9E-11 T 29-03-2018 IPR000014 PAS domain MC49_RS04530 dc18fd421cd5d1b5bd2014c6a8c2a371 606 SUPERFAMILY SSF55785 250 364 1.41E-16 T 29-03-2018 IPR000014 PAS domain MC49_RS04530 dc18fd421cd5d1b5bd2014c6a8c2a371 606 PRINTS PR00344 Bacterial sensor protein C-terminal signature 583 596 1.5E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS04530 dc18fd421cd5d1b5bd2014c6a8c2a371 606 PRINTS PR00344 Bacterial sensor protein C-terminal signature 530 544 1.5E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS04530 dc18fd421cd5d1b5bd2014c6a8c2a371 606 PRINTS PR00344 Bacterial sensor protein C-terminal signature 548 558 1.5E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS04530 dc18fd421cd5d1b5bd2014c6a8c2a371 606 PRINTS PR00344 Bacterial sensor protein C-terminal signature 559 577 1.5E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS04530 dc18fd421cd5d1b5bd2014c6a8c2a371 606 SMART SM00388 385 450 1.3E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS04530 dc18fd421cd5d1b5bd2014c6a8c2a371 606 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 257 376 7.1E-15 T 29-03-2018 IPR000014 PAS domain MC49_RS04530 dc18fd421cd5d1b5bd2014c6a8c2a371 606 SUPERFAMILY SSF55874 440 599 3.01E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS04530 dc18fd421cd5d1b5bd2014c6a8c2a371 606 Pfam PF00989 PAS fold 262 366 4.8E-16 T 29-03-2018 IPR013767 PAS fold GO:0006355 MC49_RS04530 dc18fd421cd5d1b5bd2014c6a8c2a371 606 Gene3D G3DSA:3.30.450.20 34 179 3.9E-5 T 29-03-2018 MC49_RS04530 dc18fd421cd5d1b5bd2014c6a8c2a371 606 Pfam PF00512 His Kinase A (phospho-acceptor) domain 386 450 5.3E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS04530 dc18fd421cd5d1b5bd2014c6a8c2a371 606 SMART SM00387 492 599 9.0E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS04530 dc18fd421cd5d1b5bd2014c6a8c2a371 606 Gene3D G3DSA:1.10.287.130 380 446 1.1E-17 T 29-03-2018 MC49_RS04530 dc18fd421cd5d1b5bd2014c6a8c2a371 606 Gene3D G3DSA:3.30.450.20 241 379 4.5E-24 T 29-03-2018 MC49_RS04530 dc18fd421cd5d1b5bd2014c6a8c2a371 606 SUPERFAMILY SSF103190 106 179 9.81E-5 T 29-03-2018 IPR029151 Periplasmic sensor domain-like MC49_RS04530 dc18fd421cd5d1b5bd2014c6a8c2a371 606 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 494 598 4.3E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS04070 ef746fecaead8a2b5d6831538e8645b8 59 Pfam PF00327 Ribosomal protein L30p/L7e 5 55 4.5E-19 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain MC49_RS04070 ef746fecaead8a2b5d6831538e8645b8 59 Gene3D G3DSA:3.30.1390.20 5 59 3.9E-24 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain MC49_RS04070 ef746fecaead8a2b5d6831538e8645b8 59 SUPERFAMILY SSF55129 3 59 4.97E-21 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain MC49_RS04070 ef746fecaead8a2b5d6831538e8645b8 59 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 5 59 1.0E-25 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS04070 ef746fecaead8a2b5d6831538e8645b8 59 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 2 59 21.947 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS04070 ef746fecaead8a2b5d6831538e8645b8 59 PIRSF PIRSF002211 1 59 1.3E-28 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS04070 ef746fecaead8a2b5d6831538e8645b8 59 ProSitePatterns PS00634 Ribosomal protein L30 signature. 23 55 - T 29-03-2018 IPR018038 Ribosomal protein L30, conserved site MC49_RS13555 ffd9512ad5102d1b5d6afc449299e6f7 525 SUPERFAMILY SSF52317 7 237 3.67E-55 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MC49_RS13555 ffd9512ad5102d1b5d6afc449299e6f7 525 SUPERFAMILY SSF52402 193 446 7.5E-57 T 29-03-2018 MC49_RS13555 ffd9512ad5102d1b5d6afc449299e6f7 525 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 213 525 7.3E-153 T 29-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 MC49_RS13555 ffd9512ad5102d1b5d6afc449299e6f7 525 Gene3D G3DSA:3.30.300.10 401 525 8.2E-53 T 29-03-2018 MC49_RS13555 ffd9512ad5102d1b5d6afc449299e6f7 525 Pfam PF02540 NAD synthase 224 254 1.6E-4 T 29-03-2018 IPR022310 NAD/GMP synthase MC49_RS13555 ffd9512ad5102d1b5d6afc449299e6f7 525 Pfam PF00958 GMP synthase C terminal domain 433 524 2.6E-43 T 29-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 MC49_RS13555 ffd9512ad5102d1b5d6afc449299e6f7 525 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 7 525 56.115 T 29-03-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 MC49_RS13555 ffd9512ad5102d1b5d6afc449299e6f7 525 Gene3D G3DSA:3.40.50.880 5 223 2.9E-46 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MC49_RS13555 ffd9512ad5102d1b5d6afc449299e6f7 525 Gene3D G3DSA:3.40.50.620 224 400 5.0E-34 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS13555 ffd9512ad5102d1b5d6afc449299e6f7 525 PRINTS PR00097 Anthranilate synthase component II signature 81 92 1.9E-6 T 29-03-2018 MC49_RS13555 ffd9512ad5102d1b5d6afc449299e6f7 525 PRINTS PR00097 Anthranilate synthase component II signature 54 63 1.9E-6 T 29-03-2018 MC49_RS13555 ffd9512ad5102d1b5d6afc449299e6f7 525 PRINTS PR00097 Anthranilate synthase component II signature 177 190 1.9E-6 T 29-03-2018 MC49_RS13555 ffd9512ad5102d1b5d6afc449299e6f7 525 Pfam PF00117 Glutamine amidotransferase class-I 12 200 3.0E-40 T 29-03-2018 IPR017926 Glutamine amidotransferase MC49_RS13555 ffd9512ad5102d1b5d6afc449299e6f7 525 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 10 24 4.5E-6 T 29-03-2018 MC49_RS13555 ffd9512ad5102d1b5d6afc449299e6f7 525 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 81 97 4.5E-6 T 29-03-2018 MC49_RS13555 ffd9512ad5102d1b5d6afc449299e6f7 525 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 51 65 4.5E-6 T 29-03-2018 MC49_RS13555 ffd9512ad5102d1b5d6afc449299e6f7 525 SUPERFAMILY SSF54810 405 525 4.05E-51 T 29-03-2018 MC49_RS13555 ffd9512ad5102d1b5d6afc449299e6f7 525 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 10 205 3.2E-84 T 29-03-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 MC49_RS13555 ffd9512ad5102d1b5d6afc449299e6f7 525 PRINTS PR00096 Glutamine amidotransferase superfamily signature 81 92 1.3E-7 T 29-03-2018 MC49_RS13555 ffd9512ad5102d1b5d6afc449299e6f7 525 PRINTS PR00096 Glutamine amidotransferase superfamily signature 54 63 1.3E-7 T 29-03-2018 MC49_RS13555 ffd9512ad5102d1b5d6afc449299e6f7 525 PRINTS PR00096 Glutamine amidotransferase superfamily signature 177 190 1.3E-7 T 29-03-2018 MC49_RS15955 11da1bb993a7025a22ff1c39d967c1a6 795 Pfam PF01588 Putative tRNA binding domain 45 145 4.3E-26 T 29-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 MC49_RS15955 11da1bb993a7025a22ff1c39d967c1a6 795 Pfam PF03483 B3/4 domain 212 385 1.8E-69 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 MC49_RS15955 11da1bb993a7025a22ff1c39d967c1a6 795 SMART SM00896 701 794 2.1E-46 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 MC49_RS15955 11da1bb993a7025a22ff1c39d967c1a6 795 Gene3D G3DSA:3.50.40.10 195 396 3.1E-73 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 MC49_RS15955 11da1bb993a7025a22ff1c39d967c1a6 795 Gene3D G3DSA:3.30.930.10 492 690 5.0E-42 T 29-03-2018 MC49_RS15955 11da1bb993a7025a22ff1c39d967c1a6 795 SUPERFAMILY SSF54991 697 794 1.96E-31 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 MC49_RS15955 11da1bb993a7025a22ff1c39d967c1a6 795 Gene3D G3DSA:3.30.70.380 698 794 1.1E-23 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 MC49_RS15955 11da1bb993a7025a22ff1c39d967c1a6 795 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 794 4.3E-285 T 29-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 MC49_RS15955 11da1bb993a7025a22ff1c39d967c1a6 795 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 788 47.989 T 29-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 MC49_RS15955 11da1bb993a7025a22ff1c39d967c1a6 795 Pfam PF03147 Ferredoxin-fold anticodon binding domain 701 794 1.4E-28 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 MC49_RS15955 11da1bb993a7025a22ff1c39d967c1a6 795 Gene3D G3DSA:3.30.56.10 1 55 3.1E-11 T 29-03-2018 MC49_RS15955 11da1bb993a7025a22ff1c39d967c1a6 795 Gene3D G3DSA:3.30.56.10 402 475 1.7E-25 T 29-03-2018 MC49_RS15955 11da1bb993a7025a22ff1c39d967c1a6 795 SMART SM00874 403 471 1.7E-32 T 29-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 MC49_RS15955 11da1bb993a7025a22ff1c39d967c1a6 795 SUPERFAMILY SSF55681 467 690 7.45E-59 T 29-03-2018 MC49_RS15955 11da1bb993a7025a22ff1c39d967c1a6 795 SUPERFAMILY SSF46955 404 475 6.5E-22 T 29-03-2018 IPR009061 Putative DNA-binding domain MC49_RS15955 11da1bb993a7025a22ff1c39d967c1a6 795 Pfam PF03484 tRNA synthetase B5 domain 406 471 1.6E-21 T 29-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 MC49_RS15955 11da1bb993a7025a22ff1c39d967c1a6 795 SMART SM00873 212 385 7.1E-92 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 MC49_RS15955 11da1bb993a7025a22ff1c39d967c1a6 795 SUPERFAMILY SSF56037 195 396 3.92E-76 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 MC49_RS15955 11da1bb993a7025a22ff1c39d967c1a6 795 SUPERFAMILY SSF50249 38 195 4.16E-49 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS15955 11da1bb993a7025a22ff1c39d967c1a6 795 Gene3D G3DSA:2.40.50.140 56 181 6.7E-38 T 29-03-2018 MC49_RS16260 fdd76ed2ed5b629a6903a4afa89ef0ee 510 Gene3D G3DSA:3.30.420.40 4 127 2.5E-37 T 29-03-2018 MC49_RS16260 fdd76ed2ed5b629a6903a4afa89ef0ee 510 SUPERFAMILY SSF53067 15 135 7.89E-36 T 29-03-2018 MC49_RS16260 fdd76ed2ed5b629a6903a4afa89ef0ee 510 TIGRFAM TIGR03706 exo_poly_only: exopolyphosphatase 14 308 4.9E-95 T 29-03-2018 IPR022371 Exopolyphosphatase GO:0004309|GO:0006793 MC49_RS16260 fdd76ed2ed5b629a6903a4afa89ef0ee 510 SUPERFAMILY SSF109604 315 508 2.72E-50 T 29-03-2018 MC49_RS16260 fdd76ed2ed5b629a6903a4afa89ef0ee 510 Gene3D G3DSA:3.30.420.150 128 307 8.5E-33 T 29-03-2018 MC49_RS16260 fdd76ed2ed5b629a6903a4afa89ef0ee 510 SUPERFAMILY SSF53067 139 312 2.48E-45 T 29-03-2018 MC49_RS16260 fdd76ed2ed5b629a6903a4afa89ef0ee 510 Pfam PF02541 Ppx/GppA phosphatase family 28 310 1.2E-94 T 29-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 MC49_RS16260 fdd76ed2ed5b629a6903a4afa89ef0ee 510 PIRSF PIRSF001267 5 508 2.2E-192 T 29-03-2018 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 MC49_RS09970 8e03729ad028fc2f57f9b6a1c270b39f 868 Pfam PF03797 Autotransporter beta-domain 606 841 1.7E-50 T 29-03-2018 IPR005546 Autotransporter beta-domain MC49_RS09970 8e03729ad028fc2f57f9b6a1c270b39f 868 SMART SM00869 603 857 1.6E-44 T 29-03-2018 IPR005546 Autotransporter beta-domain MC49_RS09970 8e03729ad028fc2f57f9b6a1c270b39f 868 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 455 868 3.9E-68 T 29-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 MC49_RS09970 8e03729ad028fc2f57f9b6a1c270b39f 868 SUPERFAMILY SSF103515 580 868 9.81E-47 T 29-03-2018 IPR005546 Autotransporter beta-domain MC49_RS09970 8e03729ad028fc2f57f9b6a1c270b39f 868 Gene3D G3DSA:2.40.128.130 565 868 4.5E-50 T 29-03-2018 MC49_RS04875 88e5436646d8599b5eb172e942106d22 248 Pfam PF13099 Domain of unknown function (DUF3944) 4 39 3.9E-11 T 29-03-2018 IPR025217 Domain of unknown function DUF3944 MC49_RS04875 88e5436646d8599b5eb172e942106d22 248 Pfam PF03981 Ubiquinol-cytochrome C chaperone 56 233 1.8E-6 T 29-03-2018 IPR021150 Ubiquinol-cytochrome c chaperone/UPF0174 MC49_RS14770 509d973ab80336d55a6be30632aeaec1 300 SUPERFAMILY SSF53850 91 294 1.19E-40 T 29-03-2018 MC49_RS14770 509d973ab80336d55a6be30632aeaec1 300 Pfam PF03466 LysR substrate binding domain 91 292 5.4E-38 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS14770 509d973ab80336d55a6be30632aeaec1 300 Gene3D G3DSA:3.40.190.10 93 177 3.3E-18 T 29-03-2018 MC49_RS14770 509d973ab80336d55a6be30632aeaec1 300 SUPERFAMILY SSF46785 3 112 3.63E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS14770 509d973ab80336d55a6be30632aeaec1 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.8E-15 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS14770 509d973ab80336d55a6be30632aeaec1 300 Gene3D G3DSA:1.10.10.10 1 85 3.2E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS14770 509d973ab80336d55a6be30632aeaec1 300 Gene3D G3DSA:3.40.190.10 178 263 1.2E-18 T 29-03-2018 MC49_RS09995 5fd0c54b57e8febb1527dba60987ffb1 362 Gene3D G3DSA:3.30.1330.30 111 194 1.2E-9 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like MC49_RS09995 5fd0c54b57e8febb1527dba60987ffb1 362 SUPERFAMILY SSF55315 117 194 9.3E-11 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like MC49_RS09995 5fd0c54b57e8febb1527dba60987ffb1 362 Pfam PF00588 SpoU rRNA Methylase family 214 352 3.3E-28 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MC49_RS09995 5fd0c54b57e8febb1527dba60987ffb1 362 SMART SM00967 124 199 6.3E-9 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 MC49_RS09995 5fd0c54b57e8febb1527dba60987ffb1 362 PIRSF PIRSF006280 1 361 1.8E-150 T 29-03-2018 IPR016479 tRNA/rRNA methyltransferase, YfiF, predicted GO:0008168 MC49_RS09995 5fd0c54b57e8febb1527dba60987ffb1 362 Gene3D G3DSA:3.40.1280.10 201 362 4.3E-36 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MC49_RS09995 5fd0c54b57e8febb1527dba60987ffb1 362 SUPERFAMILY SSF75217 205 359 7.19E-37 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases MC49_RS09995 5fd0c54b57e8febb1527dba60987ffb1 362 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 125 195 2.1E-12 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 MC49_RS10170 53f32e17c004263f62399a0451202660 245 SUPERFAMILY SSF161098 24 223 3.14E-37 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS10170 53f32e17c004263f62399a0451202660 245 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 47 238 9.7E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS10170 53f32e17c004263f62399a0451202660 245 Gene3D G3DSA:1.10.3720.10 2 240 7.4E-39 T 29-03-2018 MC49_RS10170 53f32e17c004263f62399a0451202660 245 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 24 132 2.3E-15 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 MC49_RS03240 f600149fd4bb2bd269df84c90f779041 350 Gene3D G3DSA:3.40.50.1370 160 331 2.6E-51 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MC49_RS03240 f600149fd4bb2bd269df84c90f779041 350 SUPERFAMILY SSF53671 14 345 1.83E-97 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MC49_RS03240 f600149fd4bb2bd269df84c90f779041 350 PRINTS PR00102 Ornithine carbamoyltransferase signature 63 77 4.5E-32 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MC49_RS03240 f600149fd4bb2bd269df84c90f779041 350 PRINTS PR00102 Ornithine carbamoyltransferase signature 96 109 4.5E-32 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MC49_RS03240 f600149fd4bb2bd269df84c90f779041 350 PRINTS PR00102 Ornithine carbamoyltransferase signature 136 150 4.5E-32 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MC49_RS03240 f600149fd4bb2bd269df84c90f779041 350 PRINTS PR00102 Ornithine carbamoyltransferase signature 323 334 4.5E-32 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MC49_RS03240 f600149fd4bb2bd269df84c90f779041 350 PRINTS PR00102 Ornithine carbamoyltransferase signature 241 251 4.5E-32 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MC49_RS03240 f600149fd4bb2bd269df84c90f779041 350 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 168 342 1.4E-54 T 29-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 MC49_RS03240 f600149fd4bb2bd269df84c90f779041 350 Gene3D G3DSA:3.40.50.1370 9 159 2.8E-51 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MC49_RS03240 f600149fd4bb2bd269df84c90f779041 350 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 147 158 2.7E-26 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MC49_RS03240 f600149fd4bb2bd269df84c90f779041 350 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 65 84 2.7E-26 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MC49_RS03240 f600149fd4bb2bd269df84c90f779041 350 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 279 288 2.7E-26 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MC49_RS03240 f600149fd4bb2bd269df84c90f779041 350 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 309 332 2.7E-26 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MC49_RS03240 f600149fd4bb2bd269df84c90f779041 350 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 65 72 - T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MC49_RS03240 f600149fd4bb2bd269df84c90f779041 350 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 21 344 2.1E-129 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MC49_RS03240 f600149fd4bb2bd269df84c90f779041 350 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 21 160 5.1E-44 T 29-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 MC49_RS03240 f600149fd4bb2bd269df84c90f779041 350 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 19 345 80.178 T 29-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 MC49_RS13740 fce7b5dc0eb543b70bbd76e7ba18f635 287 SUPERFAMILY SSF53613 15 277 2.31E-62 T 29-03-2018 IPR029056 Ribokinase-like MC49_RS13740 fce7b5dc0eb543b70bbd76e7ba18f635 287 Pfam PF01256 Carbohydrate kinase 33 269 2.4E-48 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 MC49_RS13740 fce7b5dc0eb543b70bbd76e7ba18f635 287 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 20 272 3.9E-54 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 MC49_RS13740 fce7b5dc0eb543b70bbd76e7ba18f635 287 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 214 224 - T 29-03-2018 IPR017953 Carbohydrate kinase, predicted, conserved site MC49_RS13740 fce7b5dc0eb543b70bbd76e7ba18f635 287 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 9 276 19.336 T 29-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 MC49_RS13740 fce7b5dc0eb543b70bbd76e7ba18f635 287 Gene3D G3DSA:3.40.1190.20 34 284 5.3E-43 T 29-03-2018 IPR029056 Ribokinase-like MC49_RS03600 0c5251129f997044699eb26bfca633a5 312 SUPERFAMILY SSF52540 13 154 2.5E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS03600 0c5251129f997044699eb26bfca633a5 312 Gene3D G3DSA:1.10.287.890 205 287 8.8E-25 T 29-03-2018 MC49_RS03600 0c5251129f997044699eb26bfca633a5 312 Pfam PF01715 IPP transferase 45 289 2.0E-86 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 MC49_RS03600 0c5251129f997044699eb26bfca633a5 312 Gene3D G3DSA:3.40.50.300 7 199 2.4E-62 T 29-03-2018 MC49_RS03600 0c5251129f997044699eb26bfca633a5 312 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 11 311 30.034 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 MC49_RS03600 0c5251129f997044699eb26bfca633a5 312 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 12 299 2.8E-120 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 MC49_RS00075 6c46bc692af440c5851b117fd13e0f4d 583 PIRSF PIRSF001327 1 583 1.1E-261 T 29-03-2018 IPR027541 Arsenical pump-driving ATPase GO:0005524|GO:0015446|GO:0016887|GO:0071722 MetaCyc: PWY-4621 MC49_RS00075 6c46bc692af440c5851b117fd13e0f4d 583 SUPERFAMILY SSF52540 5 241 2.67E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS00075 6c46bc692af440c5851b117fd13e0f4d 583 SUPERFAMILY SSF52540 317 537 1.08E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS00075 6c46bc692af440c5851b117fd13e0f4d 583 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 12 293 3.0E-88 T 29-03-2018 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Reactome: R-HSA-381038 MC49_RS00075 6c46bc692af440c5851b117fd13e0f4d 583 TIGRFAM TIGR04291 arsen_driv_ArsA: arsenical pump-driving ATPase 7 570 5.9E-276 T 29-03-2018 IPR027541 Arsenical pump-driving ATPase GO:0005524|GO:0015446|GO:0016887|GO:0071722 MetaCyc: PWY-4621 MC49_RS00075 6c46bc692af440c5851b117fd13e0f4d 583 Gene3D G3DSA:3.40.50.300 1 295 4.6E-58 T 29-03-2018 MC49_RS00075 6c46bc692af440c5851b117fd13e0f4d 583 Gene3D G3DSA:3.40.50.300 311 582 2.4E-42 T 29-03-2018 MC49_RS00075 6c46bc692af440c5851b117fd13e0f4d 583 SMART SM00382 7 226 2.7 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS00075 6c46bc692af440c5851b117fd13e0f4d 583 SMART SM00382 326 520 0.1 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS00075 6c46bc692af440c5851b117fd13e0f4d 583 Pfam PF02374 Anion-transporting ATPase 10 293 8.8E-86 T 29-03-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 MC49_RS00075 6c46bc692af440c5851b117fd13e0f4d 583 Pfam PF02374 Anion-transporting ATPase 329 484 3.3E-31 T 29-03-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 MC49_RS14040 17e44f402e80d7b65d4998be693f703d 589 Pfam PF02938 GAD domain 307 406 2.6E-30 T 29-03-2018 IPR029351 GAD domain Reactome: R-HSA-379726 MC49_RS14040 17e44f402e80d7b65d4998be693f703d 589 Pfam PF01336 OB-fold nucleic acid binding domain 18 101 2.8E-16 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 MC49_RS14040 17e44f402e80d7b65d4998be693f703d 589 SUPERFAMILY SSF55681 420 583 3.19E-104 T 29-03-2018 MC49_RS14040 17e44f402e80d7b65d4998be693f703d 589 SUPERFAMILY SSF55681 108 287 3.19E-104 T 29-03-2018 MC49_RS14040 17e44f402e80d7b65d4998be693f703d 589 Gene3D G3DSA:2.40.50.140 1 108 3.7E-26 T 29-03-2018 MC49_RS14040 17e44f402e80d7b65d4998be693f703d 589 Gene3D G3DSA:3.30.930.10 131 586 3.2E-101 T 29-03-2018 MC49_RS14040 17e44f402e80d7b65d4998be693f703d 589 SUPERFAMILY SSF50249 1 105 3.24E-34 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS14040 17e44f402e80d7b65d4998be693f703d 589 Pfam PF00152 tRNA synthetases class II (D, K and N) 118 558 1.4E-105 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS14040 17e44f402e80d7b65d4998be693f703d 589 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 1 585 2.9E-269 T 29-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 MC49_RS14040 17e44f402e80d7b65d4998be693f703d 589 PRINTS PR01042 Aspartyl-tRNA synthetase signature 518 532 2.5E-26 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS14040 17e44f402e80d7b65d4998be693f703d 589 PRINTS PR01042 Aspartyl-tRNA synthetase signature 190 202 2.5E-26 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS14040 17e44f402e80d7b65d4998be693f703d 589 PRINTS PR01042 Aspartyl-tRNA synthetase signature 207 220 2.5E-26 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS14040 17e44f402e80d7b65d4998be693f703d 589 PRINTS PR01042 Aspartyl-tRNA synthetase signature 474 490 2.5E-26 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS14040 17e44f402e80d7b65d4998be693f703d 589 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 1 584 33.581 T 29-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 MC49_RS14040 17e44f402e80d7b65d4998be693f703d 589 SUPERFAMILY SSF55261 288 419 1.6E-45 T 29-03-2018 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 MC49_RS01710 a01dd8203a9d57eefaeaafcf84557e10 98 Gene3D G3DSA:1.10.10.60 1 98 7.7E-27 T 29-03-2018 MC49_RS01710 a01dd8203a9d57eefaeaafcf84557e10 98 Pfam PF02954 Bacterial regulatory protein, Fis family 55 95 3.8E-14 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MC49_RS01710 a01dd8203a9d57eefaeaafcf84557e10 98 PRINTS PR01591 DNA-binding protein FIS signature 57 69 2.8E-34 T 29-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 MC49_RS01710 a01dd8203a9d57eefaeaafcf84557e10 98 PRINTS PR01591 DNA-binding protein FIS signature 26 42 2.8E-34 T 29-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 MC49_RS01710 a01dd8203a9d57eefaeaafcf84557e10 98 PRINTS PR01591 DNA-binding protein FIS signature 42 57 2.8E-34 T 29-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 MC49_RS01710 a01dd8203a9d57eefaeaafcf84557e10 98 PRINTS PR01591 DNA-binding protein FIS signature 9 26 2.8E-34 T 29-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 MC49_RS01710 a01dd8203a9d57eefaeaafcf84557e10 98 SUPERFAMILY SSF46689 4 98 8.66E-27 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS01710 a01dd8203a9d57eefaeaafcf84557e10 98 PIRSF PIRSF002097 1 98 1.1E-45 T 29-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 MC49_RS01710 a01dd8203a9d57eefaeaafcf84557e10 98 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 78 98 8.3E-13 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MC49_RS01710 a01dd8203a9d57eefaeaafcf84557e10 98 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 61 78 8.3E-13 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MC49_RS01710 a01dd8203a9d57eefaeaafcf84557e10 98 Hamap MF_00166 DNA-binding protein Fis [fis]. 1 98 33.549 T 29-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 MC49_RS04410 aa8d9999254ce2349a675c7aef76256f 192 SUPERFAMILY SSF89360 1 97 2.35E-21 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MC49_RS04410 aa8d9999254ce2349a675c7aef76256f 192 Gene3D G3DSA:2.60.300.12 1 101 7.4E-17 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MC49_RS04410 aa8d9999254ce2349a675c7aef76256f 192 TIGRFAM TIGR03341 YhgI_GntY: IscR-regulated protein YhgI 2 192 2.5E-98 T 29-03-2018 IPR017726 Fe/S biogenesis protein NfuA GO:0016226|GO:0051539|GO:0051604 MC49_RS04410 aa8d9999254ce2349a675c7aef76256f 192 Pfam PF01106 NifU-like domain 111 174 1.8E-18 T 29-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 MC49_RS04410 aa8d9999254ce2349a675c7aef76256f 192 Gene3D G3DSA:3.30.300.130 102 188 3.0E-23 T 29-03-2018 IPR034904 Fe-S cluster assembly domain MC49_RS04410 aa8d9999254ce2349a675c7aef76256f 192 SUPERFAMILY SSF117916 95 185 1.4E-22 T 29-03-2018 IPR034904 Fe-S cluster assembly domain MC49_RS04410 aa8d9999254ce2349a675c7aef76256f 192 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 119 178 4.0E-25 T 29-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 MC49_RS04410 aa8d9999254ce2349a675c7aef76256f 192 Hamap MF_01637 Fe/S biogenesis protein NfuA [nfuA]. 1 192 45.588 T 29-03-2018 IPR017726 Fe/S biogenesis protein NfuA GO:0016226|GO:0051539|GO:0051604 MC49_RS04410 aa8d9999254ce2349a675c7aef76256f 192 Pfam PF01521 Iron-sulphur cluster biosynthesis 2 99 2.1E-13 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MC49_RS16375 13f1947819d5f15bde93112fa3b4d9cd 127 SMART SM00342 24 107 4.8E-26 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MC49_RS16375 13f1947819d5f15bde93112fa3b4d9cd 127 SUPERFAMILY SSF46689 60 110 3.14E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS16375 13f1947819d5f15bde93112fa3b4d9cd 127 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 61 103 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MC49_RS16375 13f1947819d5f15bde93112fa3b4d9cd 127 Gene3D G3DSA:1.10.10.60 63 113 7.6E-14 T 29-03-2018 MC49_RS16375 13f1947819d5f15bde93112fa3b4d9cd 127 Gene3D G3DSA:1.10.10.60 7 62 3.0E-11 T 29-03-2018 MC49_RS16375 13f1947819d5f15bde93112fa3b4d9cd 127 SUPERFAMILY SSF46689 10 59 1.16E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS16375 13f1947819d5f15bde93112fa3b4d9cd 127 Pfam PF12833 Helix-turn-helix domain 30 108 6.1E-22 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MC49_RS16375 13f1947819d5f15bde93112fa3b4d9cd 127 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 91 107 6.2E-7 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MC49_RS16375 13f1947819d5f15bde93112fa3b4d9cd 127 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 76 91 6.2E-7 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MC49_RS15830 57e7a7affe8a3041b6418eacd653ae39 1029 SUPERFAMILY SSF46548 525 629 8.37E-8 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MC49_RS15830 57e7a7affe8a3041b6418eacd653ae39 1029 SUPERFAMILY SSF46548 662 698 8.37E-8 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MC49_RS15830 57e7a7affe8a3041b6418eacd653ae39 1029 SUPERFAMILY SSF55103 264 548 1.24E-52 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 MC49_RS15830 57e7a7affe8a3041b6418eacd653ae39 1029 SUPERFAMILY SSF56176 15 199 8.59E-55 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 MC49_RS15830 57e7a7affe8a3041b6418eacd653ae39 1029 SUPERFAMILY SSF56176 252 289 8.59E-55 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 MC49_RS15830 57e7a7affe8a3041b6418eacd653ae39 1029 Pfam PF13183 4Fe-4S dicluster domain 582 694 4.4E-12 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MC49_RS15830 57e7a7affe8a3041b6418eacd653ae39 1029 Pfam PF02913 FAD linked oxidases, C-terminal domain 288 546 8.2E-61 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 MC49_RS15830 57e7a7affe8a3041b6418eacd653ae39 1029 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 680 691 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MC49_RS15830 57e7a7affe8a3041b6418eacd653ae39 1029 Pfam PF01565 FAD binding domain 59 199 7.3E-38 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MC49_RS15830 57e7a7affe8a3041b6418eacd653ae39 1029 Gene3D G3DSA:1.10.1060.10 550 708 4.3E-12 T 29-03-2018 MC49_RS15830 57e7a7affe8a3041b6418eacd653ae39 1029 Gene3D G3DSA:3.30.465.10 114 311 8.0E-44 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 MC49_RS15830 57e7a7affe8a3041b6418eacd653ae39 1029 Gene3D G3DSA:3.30.43.10 2 113 4.5E-18 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 MC49_RS15830 57e7a7affe8a3041b6418eacd653ae39 1029 Gene3D G3DSA:1.10.45.10 480 546 8.0E-9 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 MC49_RS14395 4642121b2dbafbd9cf303f8d44de2a84 252 Gene3D G3DSA:1.10.10.10 166 249 7.8E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS14395 4642121b2dbafbd9cf303f8d44de2a84 252 SMART SM00100 30 151 4.0E-22 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain MC49_RS14395 4642121b2dbafbd9cf303f8d44de2a84 252 Pfam PF13545 Crp-like helix-turn-helix domain 168 242 1.0E-17 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MC49_RS14395 4642121b2dbafbd9cf303f8d44de2a84 252 Pfam PF00027 Cyclic nucleotide-binding domain 51 132 1.3E-16 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain MC49_RS14395 4642121b2dbafbd9cf303f8d44de2a84 252 SUPERFAMILY SSF46785 165 244 3.71E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS14395 4642121b2dbafbd9cf303f8d44de2a84 252 SUPERFAMILY SSF51206 23 162 4.06E-32 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like MC49_RS14395 4642121b2dbafbd9cf303f8d44de2a84 252 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 209 224 2.3E-12 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MC49_RS14395 4642121b2dbafbd9cf303f8d44de2a84 252 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 193 209 2.3E-12 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MC49_RS14395 4642121b2dbafbd9cf303f8d44de2a84 252 ProSitePatterns PS00042 Crp-type HTH domain signature. 195 218 - T 29-03-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 MC49_RS14395 4642121b2dbafbd9cf303f8d44de2a84 252 SMART SM00419 187 235 1.1E-13 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MC49_RS14395 4642121b2dbafbd9cf303f8d44de2a84 252 Gene3D G3DSA:2.60.120.10 24 165 2.8E-19 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MC49_RS09800 25f127cd043e7318a9200a88f9101130 401 SUPERFAMILY SSF103473 13 395 4.71E-26 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS09800 25f127cd043e7318a9200a88f9101130 401 Pfam PF07690 Major Facilitator Superfamily 16 348 2.7E-18 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS09800 25f127cd043e7318a9200a88f9101130 401 Gene3D G3DSA:1.20.1250.20 9 196 1.2E-16 T 29-03-2018 MC49_RS09800 25f127cd043e7318a9200a88f9101130 401 Gene3D G3DSA:1.20.1250.20 206 401 1.2E-6 T 29-03-2018 MC49_RS10670 fc1cdca348708086a9ff1d8a548e5b6d 314 Hamap MF_02043 tRNA-dihydrouridine(16) synthase [dusC]. 8 311 49.543 T 29-03-2018 IPR032886 tRNA-dihydrouridine(16) synthase GO:0002943|GO:0017150 MC49_RS10670 fc1cdca348708086a9ff1d8a548e5b6d 314 PIRSF PIRSF006621 1 314 5.5E-79 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MC49_RS10670 fc1cdca348708086a9ff1d8a548e5b6d 314 Gene3D G3DSA:3.20.20.70 1 240 8.9E-45 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS10670 fc1cdca348708086a9ff1d8a548e5b6d 314 Pfam PF01207 Dihydrouridine synthase (Dus) 5 293 8.8E-88 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MC49_RS10670 fc1cdca348708086a9ff1d8a548e5b6d 314 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 92 110 - T 29-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 MC49_RS10670 fc1cdca348708086a9ff1d8a548e5b6d 314 SUPERFAMILY SSF51395 1 301 5.74E-70 T 29-03-2018 MC49_RS02580 e508e0f1f96e6bacb55a4516501459d7 245 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 58 74 4.2E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MC49_RS02580 e508e0f1f96e6bacb55a4516501459d7 245 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 58 4.2E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MC49_RS02580 e508e0f1f96e6bacb55a4516501459d7 245 Gene3D G3DSA:3.40.1410.10 87 245 2.5E-28 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain MC49_RS02580 e508e0f1f96e6bacb55a4516501459d7 245 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 84 5.4E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MC49_RS02580 e508e0f1f96e6bacb55a4516501459d7 245 Pfam PF07702 UTRA domain 106 237 5.1E-24 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MC49_RS02580 e508e0f1f96e6bacb55a4516501459d7 245 SUPERFAMILY SSF46785 14 85 1.68E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS02580 e508e0f1f96e6bacb55a4516501459d7 245 SMART SM00345 25 84 5.1E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MC49_RS02580 e508e0f1f96e6bacb55a4516501459d7 245 Gene3D G3DSA:1.10.10.10 12 85 9.6E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS02580 e508e0f1f96e6bacb55a4516501459d7 245 SMART SM00866 102 238 1.5E-20 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MC49_RS02580 e508e0f1f96e6bacb55a4516501459d7 245 SUPERFAMILY SSF64288 72 243 1.73E-31 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain MC49_RS18495 29a44cf852805eb109bda0d2cfebde39 302 SUPERFAMILY SSF53850 93 293 2.35E-19 T 29-03-2018 MC49_RS18495 29a44cf852805eb109bda0d2cfebde39 302 TIGRFAM TIGR03298 argP: transcriptional regulator, ArgP family 5 293 3.0E-106 T 29-03-2018 IPR017685 HTH-type transcriptional regulator ArgP MC49_RS18495 29a44cf852805eb109bda0d2cfebde39 302 Hamap MF_00513 HTH-type transcriptional regulator ArgP [argP]. 1 296 54.518 T 29-03-2018 IPR023490 HTH-type transcriptional regulator ArgP, Gammaproteobacteria MC49_RS18495 29a44cf852805eb109bda0d2cfebde39 302 SUPERFAMILY SSF46785 4 110 4.9E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS18495 29a44cf852805eb109bda0d2cfebde39 302 Gene3D G3DSA:3.40.190.10 92 178 1.8E-37 T 29-03-2018 MC49_RS18495 29a44cf852805eb109bda0d2cfebde39 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 2.3E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS18495 29a44cf852805eb109bda0d2cfebde39 302 Gene3D G3DSA:1.10.10.10 2 85 3.8E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS18495 29a44cf852805eb109bda0d2cfebde39 302 Gene3D G3DSA:3.40.190.10 179 262 7.5E-8 T 29-03-2018 MC49_RS18495 29a44cf852805eb109bda0d2cfebde39 302 Pfam PF03466 LysR substrate binding domain 93 289 7.2E-13 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS18495 29a44cf852805eb109bda0d2cfebde39 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 9.3E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS18495 29a44cf852805eb109bda0d2cfebde39 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 9.3E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS18495 29a44cf852805eb109bda0d2cfebde39 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 9.3E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS15200 f56e6ef383fd2750fcadaef41d12abcc 137 Gene3D G3DSA:2.40.50.200 24 137 3.2E-35 T 29-03-2018 MC49_RS15200 f56e6ef383fd2750fcadaef41d12abcc 137 TIGRFAM TIGR00156 TIGR00156: TIGR00156 family protein 5 136 1.1E-35 T 29-03-2018 IPR016052 Bacteriophage 933W, L0136 MC49_RS15200 f56e6ef383fd2750fcadaef41d12abcc 137 SUPERFAMILY SSF101756 36 135 1.83E-31 T 29-03-2018 IPR005220 Bacterial OB-fold MC49_RS15200 f56e6ef383fd2750fcadaef41d12abcc 137 Pfam PF04076 Bacterial OB fold (BOF) protein 39 135 4.8E-34 T 29-03-2018 IPR005220 Bacterial OB-fold MC49_RS13860 7c7e383bafd6030013e1c45710acee2d 163 SUPERFAMILY SSF55826 9 160 1.83E-32 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MC49_RS13860 7c7e383bafd6030013e1c45710acee2d 163 Gene3D G3DSA:3.90.960.10 3 162 6.7E-33 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MC49_RS13860 7c7e383bafd6030013e1c45710acee2d 163 Pfam PF04073 Aminoacyl-tRNA editing domain 32 152 4.9E-24 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MC49_RS02240 a2eb956908772970640212e2c1bd75fb 468 TIGRFAM TIGR03755 conj_TIGR03755: integrating conjugative element protein, PFL_4711 family 43 451 3.6E-157 T 29-03-2018 IPR021204 Integrating conjugative element protein, PFL4711 MC49_RS08155 69f2b986c345ce79fd77211207bfbe2a 344 Pfam PF09383 NIL domain 268 340 1.0E-17 T 29-03-2018 IPR018449 NIL domain MC49_RS08155 69f2b986c345ce79fd77211207bfbe2a 344 Pfam PF00005 ABC transporter 21 169 9.2E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS08155 69f2b986c345ce79fd77211207bfbe2a 344 SMART SM00382 30 217 3.4E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS08155 69f2b986c345ce79fd77211207bfbe2a 344 SMART SM00930 265 341 2.3E-24 T 29-03-2018 IPR018449 NIL domain MC49_RS08155 69f2b986c345ce79fd77211207bfbe2a 344 SUPERFAMILY SSF52540 1 240 1.43E-84 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS08155 69f2b986c345ce79fd77211207bfbe2a 344 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS08155 69f2b986c345ce79fd77211207bfbe2a 344 Gene3D G3DSA:3.40.50.300 1 249 3.6E-76 T 29-03-2018 MC49_RS08155 69f2b986c345ce79fd77211207bfbe2a 344 TIGRFAM TIGR02314 ABC_MetN: D-methionine ABC transporter, ATP-binding protein 1 344 1.2E-185 T 29-03-2018 IPR012692 ABC transporter, methionine import, ATP-binding protein MetN, proteobacteria GO:0005524|GO:0009276|GO:0048473|GO:0048474 MC49_RS08155 69f2b986c345ce79fd77211207bfbe2a 344 SUPERFAMILY SSF55021 248 344 6.18E-23 T 29-03-2018 MC49_RS08155 69f2b986c345ce79fd77211207bfbe2a 344 Gene3D G3DSA:3.30.70.260 250 344 2.8E-24 T 29-03-2018 MC49_RS09900 dacb1e87b7a5a50ef9e7d226164fe4ac 373 TIGRFAM TIGR01799 CM_T: chorismate mutase 5 87 1.9E-44 T 29-03-2018 IPR011277 Chorismate mutase, T-protein GO:0004106|GO:0005737|GO:0006571|GO:0055114 KEGG: 00400+5.4.99.5+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7303|MetaCyc: PWY-7626 MC49_RS09900 dacb1e87b7a5a50ef9e7d226164fe4ac 373 Pfam PF01817 Chorismate mutase type II 9 86 6.5E-22 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MC49_RS09900 dacb1e87b7a5a50ef9e7d226164fe4ac 373 Gene3D G3DSA:1.10.3660.10 249 372 1.5E-30 T 29-03-2018 MC49_RS09900 dacb1e87b7a5a50ef9e7d226164fe4ac 373 Gene3D G3DSA:3.40.50.720 91 247 2.7E-24 T 29-03-2018 MC49_RS09900 dacb1e87b7a5a50ef9e7d226164fe4ac 373 SUPERFAMILY SSF48179 242 366 9.52E-40 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MC49_RS09900 dacb1e87b7a5a50ef9e7d226164fe4ac 373 PIRSF PIRSF001499 1 373 1.4E-171 T 29-03-2018 IPR008244 Bifunctional chorismate mutase/prephenate dehydrogenase T-protein GO:0004106|GO:0005737|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+5.4.99.5+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7303|MetaCyc: PWY-7626 MC49_RS09900 dacb1e87b7a5a50ef9e7d226164fe4ac 373 SMART SM00830 9 89 5.7E-32 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MC49_RS09900 dacb1e87b7a5a50ef9e7d226164fe4ac 373 SUPERFAMILY SSF48600 5 88 3.48E-24 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MC49_RS09900 dacb1e87b7a5a50ef9e7d226164fe4ac 373 SUPERFAMILY SSF51735 91 237 3.31E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS09900 dacb1e87b7a5a50ef9e7d226164fe4ac 373 Gene3D G3DSA:1.20.59.10 2 90 7.2E-25 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MC49_RS09900 dacb1e87b7a5a50ef9e7d226164fe4ac 373 Pfam PF02153 Prephenate dehydrogenase 138 343 5.1E-31 T 29-03-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 MC49_RS03430 a9b1d6aea5aa16ac90f6d9f9c64e6b20 158 Gene3D G3DSA:3.10.50.30 77 158 2.6E-27 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 MC49_RS03430 a9b1d6aea5aa16ac90f6d9f9c64e6b20 158 SUPERFAMILY SSF54534 81 157 2.75E-24 T 29-03-2018 MC49_RS03430 a9b1d6aea5aa16ac90f6d9f9c64e6b20 158 Gene3D G3DSA:1.10.287.180 3 76 1.2E-32 T 29-03-2018 MC49_RS03430 a9b1d6aea5aa16ac90f6d9f9c64e6b20 158 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 29-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 MC49_RS03430 a9b1d6aea5aa16ac90f6d9f9c64e6b20 158 SUPERFAMILY SSF46557 3 78 6.02E-29 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 MC49_RS03430 a9b1d6aea5aa16ac90f6d9f9c64e6b20 158 PIRSF PIRSF006092 1 158 4.1E-54 T 29-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 MC49_RS03430 a9b1d6aea5aa16ac90f6d9f9c64e6b20 158 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 156 33.362 T 29-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 MC49_RS03430 a9b1d6aea5aa16ac90f6d9f9c64e6b20 158 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 83 157 1.2E-28 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 MC49_RS03430 a9b1d6aea5aa16ac90f6d9f9c64e6b20 158 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 5 156 4.1E-59 T 29-03-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 MC49_RS03430 a9b1d6aea5aa16ac90f6d9f9c64e6b20 158 Pfam PF03449 Transcription elongation factor, N-terminal 4 74 3.2E-31 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 MC49_RS03430 a9b1d6aea5aa16ac90f6d9f9c64e6b20 158 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 121 137 - T 29-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 MC49_RS07585 00895b2db4742169bd77be52ca669f95 392 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 8 380 9.8E-167 T 29-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 MC49_RS07585 00895b2db4742169bd77be52ca669f95 392 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 5 388 23.424 T 29-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 MC49_RS07585 00895b2db4742169bd77be52ca669f95 392 Pfam PF06965 Na+/H+ antiporter 1 7 381 6.8E-148 T 29-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 MC49_RS07585 00895b2db4742169bd77be52ca669f95 392 Gene3D G3DSA:1.20.1530.10 3 387 1.5E-150 T 29-03-2018 IPR023171 Na/H antiporter domain MC49_RS00490 724542ed7f2db5f97abf6f919b1e61da 208 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 33 191 1.6E-24 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain MC49_RS00490 724542ed7f2db5f97abf6f919b1e61da 208 Gene3D G3DSA:3.40.50.1110 27 208 7.8E-38 T 29-03-2018 MC49_RS00490 724542ed7f2db5f97abf6f919b1e61da 208 ProSitePatterns PS01098 Lipolytic enzymes "G-D-S-L" family, serine active site. 30 40 - T 29-03-2018 IPR008265 Lipase, GDSL, active site GO:0006629|GO:0016298 Reactome: R-HSA-1482788|Reactome: R-HSA-975634 MC49_RS00490 724542ed7f2db5f97abf6f919b1e61da 208 SUPERFAMILY SSF52266 29 206 1.68E-48 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain MC49_RS03295 549a5fa83e3253fcc921ec74bd2cbe07 168 SUPERFAMILY SSF55729 1 158 3.14E-25 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS03295 549a5fa83e3253fcc921ec74bd2cbe07 168 Pfam PF13508 Acetyltransferase (GNAT) domain 45 123 2.4E-8 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MC49_RS03295 549a5fa83e3253fcc921ec74bd2cbe07 168 Gene3D G3DSA:3.40.630.30 1 149 1.2E-17 T 29-03-2018 MC49_RS14230 ffad69e94636eabee2f4b8a9b9a9eeb2 381 Gene3D G3DSA:1.10.150.80 195 293 2.3E-21 T 29-03-2018 MC49_RS14230 ffad69e94636eabee2f4b8a9b9a9eeb2 381 SUPERFAMILY SSF53098 2 209 2.49E-65 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MC49_RS14230 ffad69e94636eabee2f4b8a9b9a9eeb2 381 SMART SM00341 210 289 3.4E-16 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 MC49_RS14230 ffad69e94636eabee2f4b8a9b9a9eeb2 381 SUPERFAMILY SSF47819 298 370 1.57E-16 T 29-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 MC49_RS14230 ffad69e94636eabee2f4b8a9b9a9eeb2 381 Pfam PF00570 HRDC domain 213 278 9.5E-17 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 MC49_RS14230 ffad69e94636eabee2f4b8a9b9a9eeb2 381 Gene3D G3DSA:3.30.420.10 1 194 1.2E-40 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MC49_RS14230 ffad69e94636eabee2f4b8a9b9a9eeb2 381 SMART SM00474 3 171 1.4E-42 T 29-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 MC49_RS14230 ffad69e94636eabee2f4b8a9b9a9eeb2 381 TIGRFAM TIGR01388 rnd: ribonuclease D 5 369 3.5E-133 T 29-03-2018 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 MC49_RS14230 ffad69e94636eabee2f4b8a9b9a9eeb2 381 SUPERFAMILY SSF47819 192 300 2.18E-28 T 29-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 MC49_RS14230 ffad69e94636eabee2f4b8a9b9a9eeb2 381 Hamap MF_01899 Ribonuclease D [rnd]. 3 371 42.9 T 29-03-2018 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 MC49_RS14230 ffad69e94636eabee2f4b8a9b9a9eeb2 381 Pfam PF01612 3'-5' exonuclease 3 170 4.4E-38 T 29-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 MC49_RS05465 90b533a401b5bc37c417c13ff0ef9b5a 219 Gene3D G3DSA:1.10.10.10 9 214 6.6E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS05465 90b533a401b5bc37c417c13ff0ef9b5a 219 SUPERFAMILY SSF46785 19 196 2.59E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS00220 81d4f87561f3ae9ca07b16cf5ca9ad99 483 Pfam PF06381 Protein of unknown function (DUF1073) 87 426 2.5E-18 T 29-03-2018 IPR024459 Protein of unknown function DUF1073 MC49_RS10895 85ad32bd952ce4453d691f9edabc1b07 358 Gene3D G3DSA:3.90.1150.10 7 62 2.9E-4 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS10895 85ad32bd952ce4453d691f9edabc1b07 358 Gene3D G3DSA:3.40.640.10 63 275 1.0E-41 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS10895 85ad32bd952ce4453d691f9edabc1b07 358 SUPERFAMILY SSF53383 14 354 4.98E-82 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS10895 85ad32bd952ce4453d691f9edabc1b07 358 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 212 221 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 MC49_RS10895 85ad32bd952ce4453d691f9edabc1b07 358 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 12 353 4.5E-119 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 MC49_RS10895 85ad32bd952ce4453d691f9edabc1b07 358 Pfam PF00155 Aminotransferase class I and II 49 352 7.0E-58 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MC49_RS10895 85ad32bd952ce4453d691f9edabc1b07 358 Gene3D G3DSA:3.90.1150.10 276 355 3.2E-16 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS10895 85ad32bd952ce4453d691f9edabc1b07 358 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 10 356 54.672 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 MC49_RS00610 652eb83da1a3ba6ce07d5d961bd0ba48 109 SUPERFAMILY SSF82607 11 103 3.79E-36 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MC49_RS00610 652eb83da1a3ba6ce07d5d961bd0ba48 109 Pfam PF02575 YbaB/EbfC DNA-binding family 11 99 1.2E-35 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MC49_RS00610 652eb83da1a3ba6ce07d5d961bd0ba48 109 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 5 98 23.444 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MC49_RS00610 652eb83da1a3ba6ce07d5d961bd0ba48 109 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 1 105 9.3E-42 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MC49_RS00610 652eb83da1a3ba6ce07d5d961bd0ba48 109 PIRSF PIRSF004555 3 109 3.1E-39 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MC49_RS00610 652eb83da1a3ba6ce07d5d961bd0ba48 109 Gene3D G3DSA:3.30.1310.10 1 109 4.2E-46 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MC49_RS09545 2eb411734047abce945c190ec4ef8009 386 TIGRFAM TIGR03547 muta_rot_YjhT: mutatrotase, YjhT family 33 378 1.6E-132 T 29-03-2018 IPR019936 Mutatrotase, YjhT-like MC49_RS09545 2eb411734047abce945c190ec4ef8009 386 Pfam PF13418 Galactose oxidase, central domain 91 137 3.5E-7 T 29-03-2018 MC49_RS09545 2eb411734047abce945c190ec4ef8009 386 SUPERFAMILY SSF117281 31 161 4.45E-24 T 29-03-2018 MC49_RS09545 2eb411734047abce945c190ec4ef8009 386 SUPERFAMILY SSF117281 196 255 4.45E-24 T 29-03-2018 MC49_RS09545 2eb411734047abce945c190ec4ef8009 386 Gene3D G3DSA:2.120.10.80 19 193 1.4E-21 T 29-03-2018 IPR015915 Kelch-type beta propeller GO:0005515 MC49_RS09545 2eb411734047abce945c190ec4ef8009 386 SUPERFAMILY SSF50965 201 375 3.01E-8 T 29-03-2018 IPR011043 Galactose oxidase/kelch, beta-propeller MC49_RS09545 2eb411734047abce945c190ec4ef8009 386 Gene3D G3DSA:2.120.10.80 194 382 2.5E-14 T 29-03-2018 IPR015915 Kelch-type beta propeller GO:0005515 MC49_RS09055 d25a6376193967c99f5a74d2eb8e2127 835 Gene3D G3DSA:1.10.3810.10 214 413 2.3E-60 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 MC49_RS09055 d25a6376193967c99f5a74d2eb8e2127 835 SUPERFAMILY SSF53955 212 417 7.03E-63 T 29-03-2018 IPR023346 Lysozyme-like domain MC49_RS09055 d25a6376193967c99f5a74d2eb8e2127 835 Pfam PF14814 Bifunctional transglycosylase second domain 128 212 1.0E-26 T 29-03-2018 IPR028166 Bifunctional transglycosylase second domain KEGG: 00500+2.4.1.12|KEGG: 00550+2.4.1.129|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MC49_RS09055 d25a6376193967c99f5a74d2eb8e2127 835 Pfam PF00912 Transglycosylase 224 395 9.7E-56 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 MC49_RS09055 d25a6376193967c99f5a74d2eb8e2127 835 TIGRFAM TIGR02071 PBP_1b: penicillin-binding protein 1B 82 812 0.0 T 29-03-2018 IPR011813 Penicillin-binding protein 1B GO:0008233|GO:0008955|GO:0009252|GO:0009274|GO:0046677 KEGG: 00500+2.4.1.12|KEGG: 00550+2.4.1.129|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MC49_RS09055 d25a6376193967c99f5a74d2eb8e2127 835 Gene3D G3DSA:3.30.2060.10 127 213 2.8E-25 T 29-03-2018 MC49_RS09055 d25a6376193967c99f5a74d2eb8e2127 835 Pfam PF00905 Penicillin binding protein transpeptidase domain 488 732 6.6E-23 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MC49_RS09055 d25a6376193967c99f5a74d2eb8e2127 835 Gene3D G3DSA:3.40.710.10 415 794 3.9E-94 T 29-03-2018 MC49_RS09055 d25a6376193967c99f5a74d2eb8e2127 835 Gene3D G3DSA:1.20.5.100 72 110 4.0E-12 T 29-03-2018 MC49_RS09055 d25a6376193967c99f5a74d2eb8e2127 835 PIRSF PIRSF002799 55 835 0.0 T 29-03-2018 IPR011813 Penicillin-binding protein 1B GO:0008233|GO:0008955|GO:0009252|GO:0009274|GO:0046677 KEGG: 00500+2.4.1.12|KEGG: 00550+2.4.1.129|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MC49_RS09055 d25a6376193967c99f5a74d2eb8e2127 835 SUPERFAMILY SSF56601 377 399 2.63E-103 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MC49_RS09055 d25a6376193967c99f5a74d2eb8e2127 835 SUPERFAMILY SSF56601 428 797 2.63E-103 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MC49_RS09055 d25a6376193967c99f5a74d2eb8e2127 835 Pfam PF14812 Transmembrane domain of transglycosylase PBP1 at N-terminal 1 94 4.2E-29 T 29-03-2018 IPR032730 Transglycosylase PBP1b, N-terminal transmembrane domain MC49_RS06225 ff37e0fefee82945aabc29624a430d9d 207 Gene3D G3DSA:3.40.30.10 16 207 1.3E-31 T 29-03-2018 MC49_RS06225 ff37e0fefee82945aabc29624a430d9d 207 ProSitePatterns PS00194 Thioredoxin family active site. 40 58 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MC49_RS06225 ff37e0fefee82945aabc29624a430d9d 207 SUPERFAMILY SSF52833 20 184 1.83E-41 T 29-03-2018 IPR012336 Thioredoxin-like fold MC49_RS06225 ff37e0fefee82945aabc29624a430d9d 207 PIRSF PIRSF001488 1 207 3.3E-71 T 29-03-2018 IPR023205 Thiol:disulphide interchange protein DsbA/DsbL MC49_RS06225 ff37e0fefee82945aabc29624a430d9d 207 Pfam PF01323 DSBA-like thioredoxin domain 40 180 3.0E-21 T 29-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 MC49_RS18185 71f9b9c17f283216334603c860505dc1 1020 SUPERFAMILY SSF51445 315 593 7.35E-87 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily MC49_RS18185 71f9b9c17f283216334603c860505dc1 1020 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 430 444 - T 29-03-2018 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 MC49_RS18185 71f9b9c17f283216334603c860505dc1 1020 Pfam PF00703 Glycosyl hydrolases family 2 209 313 7.8E-12 T 29-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 MC49_RS18185 71f9b9c17f283216334603c860505dc1 1020 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 315 598 8.0E-114 T 29-03-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 MC49_RS18185 71f9b9c17f283216334603c860505dc1 1020 PRINTS PR00132 Glycosyl hydrolase family 2 signature 324 338 6.1E-31 T 29-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 MC49_RS18185 71f9b9c17f283216334603c860505dc1 1020 PRINTS PR00132 Glycosyl hydrolase family 2 signature 355 373 6.1E-31 T 29-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 MC49_RS18185 71f9b9c17f283216334603c860505dc1 1020 PRINTS PR00132 Glycosyl hydrolase family 2 signature 501 516 6.1E-31 T 29-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 MC49_RS18185 71f9b9c17f283216334603c860505dc1 1020 PRINTS PR00132 Glycosyl hydrolase family 2 signature 135 150 6.1E-31 T 29-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 MC49_RS18185 71f9b9c17f283216334603c860505dc1 1020 PRINTS PR00132 Glycosyl hydrolase family 2 signature 430 445 6.1E-31 T 29-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 MC49_RS18185 71f9b9c17f283216334603c860505dc1 1020 Gene3D G3DSA:2.60.40.10 209 313 4.1E-21 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS18185 71f9b9c17f283216334603c860505dc1 1020 Gene3D G3DSA:3.20.20.80 314 594 1.4E-70 T 29-03-2018 MC49_RS18185 71f9b9c17f283216334603c860505dc1 1020 SUPERFAMILY SSF49303 591 697 1.01E-20 T 29-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 MC49_RS18185 71f9b9c17f283216334603c860505dc1 1020 SUPERFAMILY SSF49303 209 313 1.81E-22 T 29-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 MC49_RS18185 71f9b9c17f283216334603c860505dc1 1020 Gene3D G3DSA:2.70.98.10 705 994 4.9E-86 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 MC49_RS18185 71f9b9c17f283216334603c860505dc1 1020 Pfam PF16353 Domain of unknown function(DUF4981) 609 694 1.8E-14 T 29-03-2018 IPR032312 Beta-galactosidase, domain 4 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MC49_RS18185 71f9b9c17f283216334603c860505dc1 1020 SUPERFAMILY SSF49785 2 207 7.41E-62 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS18185 71f9b9c17f283216334603c860505dc1 1020 Pfam PF02929 Beta galactosidase small chain 725 992 4.3E-66 T 29-03-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MC49_RS18185 71f9b9c17f283216334603c860505dc1 1020 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 365 390 - T 29-03-2018 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 MC49_RS18185 71f9b9c17f283216334603c860505dc1 1020 Gene3D G3DSA:2.60.120.260 1 207 1.9E-62 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS18185 71f9b9c17f283216334603c860505dc1 1020 SUPERFAMILY SSF74650 708 994 5.34E-82 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 MC49_RS18185 71f9b9c17f283216334603c860505dc1 1020 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 42 207 2.8E-52 T 29-03-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MC49_RS18185 71f9b9c17f283216334603c860505dc1 1020 Gene3D G3DSA:2.60.40.10 595 702 2.4E-22 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS18185 71f9b9c17f283216334603c860505dc1 1020 SMART SM01038 722 993 2.9E-117 T 29-03-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MC49_RS15750 133990197a1b6a03f7b9ed30d260971b 403 Pfam PF07690 Major Facilitator Superfamily 18 348 1.1E-43 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS15750 133990197a1b6a03f7b9ed30d260971b 403 SUPERFAMILY SSF103473 9 386 6.28E-64 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS15750 133990197a1b6a03f7b9ed30d260971b 403 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 10 387 1.0E-104 T 29-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 MC49_RS15750 133990197a1b6a03f7b9ed30d260971b 403 Gene3D G3DSA:1.20.1250.20 197 393 1.6E-16 T 29-03-2018 MC49_RS15750 133990197a1b6a03f7b9ed30d260971b 403 Gene3D G3DSA:1.20.1250.20 3 190 5.1E-33 T 29-03-2018 MC49_RS15455 0ddd8749e02db831c2721dc8a4b65857 764 Gene3D G3DSA:3.90.870.10 191 394 3.3E-47 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain MC49_RS15455 0ddd8749e02db831c2721dc8a4b65857 764 Gene3D G3DSA:3.30.420.40 587 740 2.0E-25 T 29-03-2018 MC49_RS15455 0ddd8749e02db831c2721dc8a4b65857 764 Pfam PF07503 HypF finger 157 188 1.0E-15 T 29-03-2018 IPR011125 Zinc finger, HypF-type GO:0008270 MC49_RS15455 0ddd8749e02db831c2721dc8a4b65857 764 Pfam PF07503 HypF finger 106 139 6.5E-16 T 29-03-2018 IPR011125 Zinc finger, HypF-type GO:0008270 MC49_RS15455 0ddd8749e02db831c2721dc8a4b65857 764 PIRSF PIRSF006256 1 764 1.7E-266 T 29-03-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 MC49_RS15455 0ddd8749e02db831c2721dc8a4b65857 764 Gene3D G3DSA:3.30.420.40 454 519 0.0011 T 29-03-2018 MC49_RS15455 0ddd8749e02db831c2721dc8a4b65857 764 SUPERFAMILY SSF55821 174 395 2.44E-43 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain MC49_RS15455 0ddd8749e02db831c2721dc8a4b65857 764 ProSitePatterns PS00150 Acylphosphatase signature 1. 9 19 - T 29-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 MC49_RS15455 0ddd8749e02db831c2721dc8a4b65857 764 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 7 758 2.0E-237 T 29-03-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 MC49_RS15455 0ddd8749e02db831c2721dc8a4b65857 764 SUPERFAMILY SSF53067 564 760 5.27E-6 T 29-03-2018 MC49_RS15455 0ddd8749e02db831c2721dc8a4b65857 764 SUPERFAMILY SSF53067 499 530 5.27E-6 T 29-03-2018 MC49_RS15455 0ddd8749e02db831c2721dc8a4b65857 764 Pfam PF01300 Telomere recombination 209 386 1.8E-43 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 MC49_RS15455 0ddd8749e02db831c2721dc8a4b65857 764 SUPERFAMILY SSF54975 4 88 6.98E-18 T 29-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 MC49_RS15455 0ddd8749e02db831c2721dc8a4b65857 764 Pfam PF00708 Acylphosphatase 5 88 2.6E-16 T 29-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 MC49_RS15455 0ddd8749e02db831c2721dc8a4b65857 764 Gene3D G3DSA:3.30.70.100 1 96 2.0E-20 T 29-03-2018 MC49_RS07425 f7d623e4765056d9e98d6d159c754a98 330 Pfam PF03253 Urea transporter 24 320 2.0E-91 T 29-03-2018 IPR004937 Urea transporter GO:0015204|GO:0016021|GO:0071918 Reactome: R-HSA-425366 MC49_RS07425 f7d623e4765056d9e98d6d159c754a98 330 Gene3D G3DSA:1.10.3430.10 7 326 2.2E-89 T 29-03-2018 MC49_RS07425 f7d623e4765056d9e98d6d159c754a98 330 TIGRFAM TIGR03441 urea_trans_yut: urea transporter 21 319 1.2E-98 T 29-03-2018 IPR017807 Urea transporter, bacteria GO:0015204|GO:0016021|GO:0071918 MC49_RS07425 f7d623e4765056d9e98d6d159c754a98 330 PIRSF PIRSF016502 7 330 4.0E-97 T 29-03-2018 IPR004937 Urea transporter GO:0015204|GO:0016021|GO:0071918 Reactome: R-HSA-425366 MC49_RS03595 8e73532ce34623fa99cf41c8046d4084 101 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 5 64 1.9E-29 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 MC49_RS03595 8e73532ce34623fa99cf41c8046d4084 101 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 3 64 27.396 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 MC49_RS03595 8e73532ce34623fa99cf41c8046d4084 101 Gene3D G3DSA:2.30.30.100 4 73 1.3E-33 T 29-03-2018 MC49_RS03595 8e73532ce34623fa99cf41c8046d4084 101 Pfam PF17209 Hfq protein 7 69 4.7E-31 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 MC49_RS03595 8e73532ce34623fa99cf41c8046d4084 101 SUPERFAMILY SSF50182 7 69 4.04E-24 T 29-03-2018 IPR010920 LSM domain MC49_RS11300 45e02f12bde0697cc65da469798feabf 581 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 432 533 3.6E-9 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 MC49_RS11300 45e02f12bde0697cc65da469798feabf 581 Gene3D G3DSA:3.30.230.10 325 556 5.4E-29 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MC49_RS11300 45e02f12bde0697cc65da469798feabf 581 SUPERFAMILY SSF54211 346 538 1.4E-33 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MC49_RS11300 45e02f12bde0697cc65da469798feabf 581 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 459 478 2.2E-9 T 29-03-2018 MC49_RS11300 45e02f12bde0697cc65da469798feabf 581 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 346 362 2.2E-9 T 29-03-2018 MC49_RS11300 45e02f12bde0697cc65da469798feabf 581 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 489 507 2.2E-9 T 29-03-2018 MC49_RS11300 45e02f12bde0697cc65da469798feabf 581 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 429 448 2.2E-9 T 29-03-2018 MC49_RS11300 45e02f12bde0697cc65da469798feabf 581 Pfam PF13654 AAA domain 120 310 1.8E-21 T 29-03-2018 MC49_RS05530 a740a7a0941e6118535c165124d96619 197 Gene3D G3DSA:1.10.10.60 2 57 8.3E-11 T 29-03-2018 MC49_RS05530 a740a7a0941e6118535c165124d96619 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 60 2.9E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS05530 a740a7a0941e6118535c165124d96619 197 Hamap MF_01839 Nucleoid occlusion factor SlmA [slmA]. 1 197 38.88 T 29-03-2018 IPR023769 Nucleoid occlusion factor SlmA GO:0010974 MC49_RS05530 a740a7a0941e6118535c165124d96619 197 SUPERFAMILY SSF48498 85 194 1.46E-6 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MC49_RS05530 a740a7a0941e6118535c165124d96619 197 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 57 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MC49_RS05530 a740a7a0941e6118535c165124d96619 197 SUPERFAMILY SSF46689 9 73 1.2E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS05530 a740a7a0941e6118535c165124d96619 197 Gene3D G3DSA:1.10.357.10 58 194 5.9E-15 T 29-03-2018 MC49_RS08080 e19eb90f528f818a2ef1232e0d95f3d2 342 Gene3D G3DSA:2.160.10.10 23 136 6.0E-16 T 29-03-2018 MC49_RS08080 e19eb90f528f818a2ef1232e0d95f3d2 342 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 110 144 1.0E-8 T 29-03-2018 IPR001451 Hexapeptide repeat MC49_RS08080 e19eb90f528f818a2ef1232e0d95f3d2 342 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 145 179 2.6E-8 T 29-03-2018 IPR001451 Hexapeptide repeat MC49_RS08080 e19eb90f528f818a2ef1232e0d95f3d2 342 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 222 255 3.7E-7 T 29-03-2018 IPR001451 Hexapeptide repeat MC49_RS08080 e19eb90f528f818a2ef1232e0d95f3d2 342 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 225 253 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MC49_RS08080 e19eb90f528f818a2ef1232e0d95f3d2 342 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 259 285 0.0011 T 29-03-2018 IPR001451 Hexapeptide repeat MC49_RS08080 e19eb90f528f818a2ef1232e0d95f3d2 342 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 9 326 35.965 T 29-03-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 MC49_RS08080 e19eb90f528f818a2ef1232e0d95f3d2 342 SUPERFAMILY SSF51161 33 316 5.36E-88 T 29-03-2018 IPR011004 Trimeric LpxA-like MC49_RS08080 e19eb90f528f818a2ef1232e0d95f3d2 342 Gene3D G3DSA:2.160.10.10 137 309 1.1E-44 T 29-03-2018 MC49_RS08080 e19eb90f528f818a2ef1232e0d95f3d2 342 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 8 329 9.2E-123 T 29-03-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 MC49_RS08080 e19eb90f528f818a2ef1232e0d95f3d2 342 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 22 88 1.4E-23 T 29-03-2018 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 MC49_RS14955 9ad66f84c884407b0b1a430a01c10541 229 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 2 203 23.389 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 MC49_RS14955 9ad66f84c884407b0b1a430a01c10541 229 SUPERFAMILY SSF52540 1 213 2.97E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS14955 9ad66f84c884407b0b1a430a01c10541 229 PIRSF PIRSF006755 1 225 6.3E-62 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 MC49_RS14955 9ad66f84c884407b0b1a430a01c10541 229 Pfam PF13500 AAA domain 3 201 8.4E-29 T 29-03-2018 MC49_RS14955 9ad66f84c884407b0b1a430a01c10541 229 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 6 170 1.3E-37 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 MC49_RS14955 9ad66f84c884407b0b1a430a01c10541 229 Gene3D G3DSA:3.40.50.300 2 212 2.4E-43 T 29-03-2018 MC49_RS15370 088b961121f107b0ae35d7c320900e0d 158 Pfam PF02810 SEC-C motif 8 24 4.9E-8 T 29-03-2018 IPR004027 SEC-C motif MC49_RS15370 088b961121f107b0ae35d7c320900e0d 158 Pfam PF02810 SEC-C motif 141 158 1.0E-10 T 29-03-2018 IPR004027 SEC-C motif MC49_RS15370 088b961121f107b0ae35d7c320900e0d 158 Gene3D G3DSA:3.10.450.50 143 158 0.23 T 29-03-2018 MC49_RS15370 088b961121f107b0ae35d7c320900e0d 158 Gene3D G3DSA:3.10.450.50 8 136 7.3E-41 T 29-03-2018 MC49_RS15370 088b961121f107b0ae35d7c320900e0d 158 SUPERFAMILY SSF103642 5 25 3.11E-5 T 29-03-2018 MC49_RS15370 088b961121f107b0ae35d7c320900e0d 158 Hamap MF_00612 UPF0225 protein YchJ [ychJ]. 6 135 25.818 T 29-03-2018 IPR023006 Uncharacterised protein family UPF0225 MC49_RS15370 088b961121f107b0ae35d7c320900e0d 158 SUPERFAMILY SSF103642 139 157 1.57E-7 T 29-03-2018 MC49_RS15370 088b961121f107b0ae35d7c320900e0d 158 SUPERFAMILY SSF54427 31 135 4.38E-32 T 29-03-2018 IPR032710 NTF2-like domain MC49_RS14875 2795d621e34d95eb32e8aac407e32445 196 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 103 181 9.9E-11 T 29-03-2018 MC49_RS14875 2795d621e34d95eb32e8aac407e32445 196 Gene3D G3DSA:1.10.357.10 61 196 4.3E-20 T 29-03-2018 MC49_RS14875 2795d621e34d95eb32e8aac407e32445 196 SUPERFAMILY SSF48498 84 190 8.07E-16 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MC49_RS14875 2795d621e34d95eb32e8aac407e32445 196 Gene3D G3DSA:1.10.10.60 5 60 3.3E-19 T 29-03-2018 MC49_RS14875 2795d621e34d95eb32e8aac407e32445 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 1.0E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS14875 2795d621e34d95eb32e8aac407e32445 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 5.1E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS14875 2795d621e34d95eb32e8aac407e32445 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 5.1E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS14875 2795d621e34d95eb32e8aac407e32445 196 SUPERFAMILY SSF46689 3 67 1.54E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS08795 1239408c99d8cef68801aeae6fba198a 217 SUPERFAMILY SSF55469 1 215 2.22E-62 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MC49_RS08795 1239408c99d8cef68801aeae6fba198a 217 Pfam PF00881 Nitroreductase family 8 193 6.4E-25 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MC49_RS08795 1239408c99d8cef68801aeae6fba198a 217 Gene3D G3DSA:3.40.109.10 1 217 8.5E-37 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MC49_RS14050 7122da21d51ce1933f353ba6b075f1b9 247 Gene3D G3DSA:1.10.10.200 1 78 9.7E-30 T 29-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like MC49_RS14050 7122da21d51ce1933f353ba6b075f1b9 247 SUPERFAMILY SSF75625 3 244 2.75E-95 T 29-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MC49_RS14050 7122da21d51ce1933f353ba6b075f1b9 247 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 239 36.288 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MC49_RS14050 7122da21d51ce1933f353ba6b075f1b9 247 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 237 2.5E-103 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MC49_RS14050 7122da21d51ce1933f353ba6b075f1b9 247 Gene3D G3DSA:3.30.70.980 83 178 4.0E-33 T 29-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MC49_RS14050 7122da21d51ce1933f353ba6b075f1b9 247 Pfam PF01709 Transcriptional regulator 5 236 2.8E-94 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MC49_RS14050 7122da21d51ce1933f353ba6b075f1b9 247 Gene3D G3DSA:3.30.70.980 179 247 7.7E-12 T 29-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MC49_RS06055 92d9be5f76ae99e24edb49f3515683ab 231 Pfam PF12105 SpoU, rRNA methylase, C-terminal 162 216 1.6E-22 T 29-03-2018 IPR022724 RNA methyltransferase, SpoU/TrmH type, C-terminal GO:0009020 MC49_RS06055 92d9be5f76ae99e24edb49f3515683ab 231 Pfam PF00588 SpoU rRNA Methylase family 20 158 6.5E-38 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MC49_RS06055 92d9be5f76ae99e24edb49f3515683ab 231 SUPERFAMILY SSF75217 5 175 8.9E-50 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases MC49_RS06055 92d9be5f76ae99e24edb49f3515683ab 231 Gene3D G3DSA:3.40.1280.10 1 190 1.6E-48 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MC49_RS06055 92d9be5f76ae99e24edb49f3515683ab 231 Hamap MF_02060 tRNA (guanosine(18)-2'-O)-methyltransferase [trmH]. 2 196 36.103 T 29-03-2018 IPR033671 tRNA (guanosine(18)-2'-O)-methyltransferase GO:0008168|GO:0030488 MC49_RS19065 9a30f49c239b1a5b51b8d38c2e4e0c32 550 Gene3D G3DSA:3.40.50.1220 188 344 3.7E-27 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MC49_RS19065 9a30f49c239b1a5b51b8d38c2e4e0c32 550 Gene3D G3DSA:3.40.50.970 5 187 4.2E-36 T 29-03-2018 MC49_RS19065 9a30f49c239b1a5b51b8d38c2e4e0c32 550 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 394 526 3.8E-20 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MC49_RS19065 9a30f49c239b1a5b51b8d38c2e4e0c32 550 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 201 319 5.2E-22 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MC49_RS19065 9a30f49c239b1a5b51b8d38c2e4e0c32 550 SUPERFAMILY SSF52467 166 339 2.26E-33 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MC49_RS19065 9a30f49c239b1a5b51b8d38c2e4e0c32 550 Gene3D G3DSA:3.40.50.970 345 542 7.4E-39 T 29-03-2018 MC49_RS19065 9a30f49c239b1a5b51b8d38c2e4e0c32 550 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 9 178 6.2E-25 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MC49_RS19065 9a30f49c239b1a5b51b8d38c2e4e0c32 550 SUPERFAMILY SSF52518 8 181 2.06E-35 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MC49_RS19065 9a30f49c239b1a5b51b8d38c2e4e0c32 550 PIRSF PIRSF036565 5 547 1.3E-177 T 29-03-2018 IPR012110 Thiamine pyrophosphate (TPP)-dependent enzyme GO:0016831 MC49_RS19065 9a30f49c239b1a5b51b8d38c2e4e0c32 550 SUPERFAMILY SSF52518 357 543 2.5E-44 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MC49_RS01425 a327cbf831b617e448deea2c7ebe8f67 216 SUPERFAMILY SSF52317 1 215 7.91E-55 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MC49_RS01425 a327cbf831b617e448deea2c7ebe8f67 216 Gene3D G3DSA:3.40.50.880 1 216 4.8E-32 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MC49_RS01425 a327cbf831b617e448deea2c7ebe8f67 216 PIRSF PIRSF006320 1 216 3.0E-100 T 29-03-2018 IPR026041 Glyoxalase ElbB MC49_RS02755 0291de6a2a6cd52cfabf63490e882fa6 350 Pfam PF07201 HrpJ-like domain 45 203 1.6E-23 T 29-03-2018 IPR010812 Hypersensitivity response secretion-like, HrpJ GO:0009405|GO:0019867|GO:0046903 MC49_RS02755 0291de6a2a6cd52cfabf63490e882fa6 350 PRINTS PR01344 Salmonella/Shigella invasion protein E (InvE) signature 223 243 6.9E-9 T 29-03-2018 IPR003520 Salmonella/Shigella invasion protein E GO:0009306 MC49_RS02755 0291de6a2a6cd52cfabf63490e882fa6 350 PRINTS PR01344 Salmonella/Shigella invasion protein E (InvE) signature 41 61 6.9E-9 T 29-03-2018 IPR003520 Salmonella/Shigella invasion protein E GO:0009306 MC49_RS02755 0291de6a2a6cd52cfabf63490e882fa6 350 PRINTS PR01344 Salmonella/Shigella invasion protein E (InvE) signature 103 122 6.9E-9 T 29-03-2018 IPR003520 Salmonella/Shigella invasion protein E GO:0009306 MC49_RS02755 0291de6a2a6cd52cfabf63490e882fa6 350 SUPERFAMILY SSF140591 58 249 5.89E-30 T 29-03-2018 MC49_RS02755 0291de6a2a6cd52cfabf63490e882fa6 350 TIGRFAM TIGR02568 LcrE: type III secretion regulator YopN/LcrE/InvE/MxiC 47 261 1.9E-26 T 29-03-2018 IPR013401 Type III secretion regulator, YopN/LcrE/InvE/MxiC GO:0009986|GO:0030254|GO:0050709 MC49_RS17055 38e80bb802e8693605854cd112f54979 116 Pfam PF01230 HIT domain 12 109 1.0E-29 T 29-03-2018 IPR001310 Histidine triad (HIT) protein MC49_RS17055 38e80bb802e8693605854cd112f54979 116 ProSitePatterns PS00892 HIT domain signature. 88 106 - T 29-03-2018 IPR019808 Histidine triad, conserved site MC49_RS17055 38e80bb802e8693605854cd112f54979 116 SUPERFAMILY SSF54197 2 113 1.7E-36 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 MC49_RS17055 38e80bb802e8693605854cd112f54979 116 Gene3D G3DSA:3.30.428.10 1 109 4.5E-29 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 MC49_RS17055 38e80bb802e8693605854cd112f54979 116 PRINTS PR00332 Histidine triad family signature 95 105 7.3E-20 T 29-03-2018 IPR001310 Histidine triad (HIT) protein MC49_RS17055 38e80bb802e8693605854cd112f54979 116 PRINTS PR00332 Histidine triad family signature 6 22 7.3E-20 T 29-03-2018 IPR001310 Histidine triad (HIT) protein MC49_RS17055 38e80bb802e8693605854cd112f54979 116 PRINTS PR00332 Histidine triad family signature 27 45 7.3E-20 T 29-03-2018 IPR001310 Histidine triad (HIT) protein MC49_RS09690 f7e69262523ef2fc7163adff7531752a 192 TIGRFAM TIGR00441 gmhA: phosphoheptose isomerase 35 187 3.0E-82 T 29-03-2018 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 MC49_RS09690 f7e69262523ef2fc7163adff7531752a 192 Pfam PF13580 SIS domain 24 146 7.4E-31 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MC49_RS09690 f7e69262523ef2fc7163adff7531752a 192 Gene3D G3DSA:3.40.50.10490 1 192 8.9E-40 T 29-03-2018 MC49_RS09690 f7e69262523ef2fc7163adff7531752a 192 SUPERFAMILY SSF53697 1 189 4.25E-51 T 29-03-2018 MC49_RS09690 f7e69262523ef2fc7163adff7531752a 192 Hamap MF_00067 Phosphoheptose isomerase [gmhA]. 1 190 37.742 T 29-03-2018 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 MC49_RS02135 08c824deafe4dc840ddefc852fce78ef 474 Pfam PF00206 Lyase 13 345 4.1E-106 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal MC49_RS02135 08c824deafe4dc840ddefc852fce78ef 474 Gene3D G3DSA:1.10.40.30 418 458 4.0E-17 T 29-03-2018 MC49_RS02135 08c824deafe4dc840ddefc852fce78ef 474 ProSitePatterns PS00163 Fumarate lyases signature. 320 329 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 MC49_RS02135 08c824deafe4dc840ddefc852fce78ef 474 SUPERFAMILY SSF48557 1 457 1.27E-143 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 MC49_RS02135 08c824deafe4dc840ddefc852fce78ef 474 Gene3D G3DSA:1.20.200.10 142 417 5.4E-73 T 29-03-2018 MC49_RS02135 08c824deafe4dc840ddefc852fce78ef 474 PRINTS PR00149 Fumarate lyase superfamily signature 274 301 8.8E-29 T 29-03-2018 IPR000362 Fumarate lyase family MC49_RS02135 08c824deafe4dc840ddefc852fce78ef 474 PRINTS PR00149 Fumarate lyase superfamily signature 183 201 8.8E-29 T 29-03-2018 IPR000362 Fumarate lyase family MC49_RS02135 08c824deafe4dc840ddefc852fce78ef 474 PRINTS PR00149 Fumarate lyase superfamily signature 320 336 8.8E-29 T 29-03-2018 IPR000362 Fumarate lyase family MC49_RS02135 08c824deafe4dc840ddefc852fce78ef 474 PRINTS PR00149 Fumarate lyase superfamily signature 138 156 8.8E-29 T 29-03-2018 IPR000362 Fumarate lyase family MC49_RS02135 08c824deafe4dc840ddefc852fce78ef 474 PRINTS PR00145 Argininosuccinate lyase family signature 178 198 1.9E-6 T 29-03-2018 MC49_RS02135 08c824deafe4dc840ddefc852fce78ef 474 PRINTS PR00145 Argininosuccinate lyase family signature 320 336 1.9E-6 T 29-03-2018 MC49_RS02135 08c824deafe4dc840ddefc852fce78ef 474 PRINTS PR00145 Argininosuccinate lyase family signature 137 159 1.9E-6 T 29-03-2018 MC49_RS02135 08c824deafe4dc840ddefc852fce78ef 474 Gene3D G3DSA:1.10.275.10 3 141 6.2E-51 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal MC49_RS02135 08c824deafe4dc840ddefc852fce78ef 474 Pfam PF10415 Fumarase C C-terminus 411 462 1.1E-16 T 29-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MC49_RS02135 08c824deafe4dc840ddefc852fce78ef 474 TIGRFAM TIGR00839 aspA: aspartate ammonia-lyase 6 473 7.7E-257 T 29-03-2018 IPR004708 Aspartate ammonia-lyase GO:0006531|GO:0008797 KEGG: 00250+4.3.1.1 MC49_RS12640 d3af542c1aa06e0f554e93541183d746 566 Pfam PF08345 Flagellar M-ring protein C-terminal 255 439 5.6E-47 T 29-03-2018 IPR013556 Flagellar M-ring C-terminal MC49_RS12640 d3af542c1aa06e0f554e93541183d746 566 PIRSF PIRSF004862 5 566 1.3E-152 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 MC49_RS12640 d3af542c1aa06e0f554e93541183d746 566 Pfam PF01514 Secretory protein of YscJ/FliF family 34 223 4.0E-75 T 29-03-2018 IPR006182 Secretory protein YscJ/FliF MC49_RS12640 d3af542c1aa06e0f554e93541183d746 566 PRINTS PR01009 Flagellar M-ring protein signature 268 286 2.6E-39 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 MC49_RS12640 d3af542c1aa06e0f554e93541183d746 566 PRINTS PR01009 Flagellar M-ring protein signature 363 387 2.6E-39 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 MC49_RS12640 d3af542c1aa06e0f554e93541183d746 566 PRINTS PR01009 Flagellar M-ring protein signature 156 170 2.6E-39 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 MC49_RS12640 d3af542c1aa06e0f554e93541183d746 566 PRINTS PR01009 Flagellar M-ring protein signature 124 142 2.6E-39 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 MC49_RS12640 d3af542c1aa06e0f554e93541183d746 566 PRINTS PR01009 Flagellar M-ring protein signature 199 217 2.6E-39 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 MC49_RS12640 d3af542c1aa06e0f554e93541183d746 566 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 19 564 5.7E-152 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 MC49_RS12640 d3af542c1aa06e0f554e93541183d746 566 Gene3D G3DSA:3.30.70.1530 55 118 3.3E-8 T 29-03-2018 MC49_RS09285 608449f0f45bdb61c8516b19b6b3172d 380 Pfam PF12500 TRSP domain C terminus to PRTase_2 273 357 9.2E-20 T 29-03-2018 IPR022537 TRSP domain MC49_RS09285 608449f0f45bdb61c8516b19b6b3172d 380 PIRSF PIRSF020967 1 379 3.0E-159 T 29-03-2018 IPR011214 Uncharacterised conserved protein UCP020967 MC49_RS09285 608449f0f45bdb61c8516b19b6b3172d 380 Gene3D G3DSA:3.40.50.2020 19 217 1.3E-16 T 29-03-2018 MC49_RS09285 608449f0f45bdb61c8516b19b6b3172d 380 Pfam PF15609 Phosphoribosyl transferase 33 219 1.4E-61 T 29-03-2018 MC49_RS09285 608449f0f45bdb61c8516b19b6b3172d 380 SUPERFAMILY SSF53271 27 201 2.27E-12 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like MC49_RS09665 991824c61792e0ada6d9063b14f7b681 304 Gene3D G3DSA:3.40.190.10 184 264 1.9E-19 T 29-03-2018 MC49_RS09665 991824c61792e0ada6d9063b14f7b681 304 SUPERFAMILY SSF53850 95 295 1.02E-38 T 29-03-2018 MC49_RS09665 991824c61792e0ada6d9063b14f7b681 304 Gene3D G3DSA:1.10.10.10 1 94 5.9E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS09665 991824c61792e0ada6d9063b14f7b681 304 SUPERFAMILY SSF46785 3 83 2.99E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS09665 991824c61792e0ada6d9063b14f7b681 304 Gene3D G3DSA:3.40.190.10 95 183 2.0E-21 T 29-03-2018 MC49_RS09665 991824c61792e0ada6d9063b14f7b681 304 Pfam PF03466 LysR substrate binding domain 93 292 1.0E-38 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS09665 991824c61792e0ada6d9063b14f7b681 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 5.5E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS09665 991824c61792e0ada6d9063b14f7b681 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 5.5E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS09665 991824c61792e0ada6d9063b14f7b681 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 5.5E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS09665 991824c61792e0ada6d9063b14f7b681 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 9.3E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS18730 3a0470f90afc570661952d1a1faeec57 533 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 12 28 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MC49_RS18730 3a0470f90afc570661952d1a1faeec57 533 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 199 212 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MC49_RS18730 3a0470f90afc570661952d1a1faeec57 533 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 2 509 42.29 T 29-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MC49_RS18730 3a0470f90afc570661952d1a1faeec57 533 Gene3D G3DSA:3.20.20.70 1 332 2.6E-109 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS18730 3a0470f90afc570661952d1a1faeec57 533 SUPERFAMILY SSF51569 1 291 4.4E-100 T 29-03-2018 MC49_RS18730 3a0470f90afc570661952d1a1faeec57 533 SMART SM00917 369 500 1.4E-37 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MC49_RS18730 3a0470f90afc570661952d1a1faeec57 533 SUPERFAMILY SSF110921 390 499 1.57E-24 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MC49_RS18730 3a0470f90afc570661952d1a1faeec57 533 Pfam PF00682 HMGL-like 5 273 1.1E-100 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 MC49_RS18730 3a0470f90afc570661952d1a1faeec57 533 Pfam PF08502 LeuA allosteric (dimerisation) domain 369 499 2.5E-33 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MC49_RS18730 3a0470f90afc570661952d1a1faeec57 533 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 5 497 3.0E-234 T 29-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MC49_RS07605 3600d2a5faa6a17d4e9676724f204082 937 SUPERFAMILY SSF52374 403 647 1.8E-136 T 29-03-2018 MC49_RS07605 3600d2a5faa6a17d4e9676724f204082 937 SUPERFAMILY SSF52374 3 202 1.8E-136 T 29-03-2018 MC49_RS07605 3600d2a5faa6a17d4e9676724f204082 937 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 401 416 4.7E-33 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MC49_RS07605 3600d2a5faa6a17d4e9676724f204082 937 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 561 570 4.7E-33 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MC49_RS07605 3600d2a5faa6a17d4e9676724f204082 937 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 238 261 4.7E-33 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MC49_RS07605 3600d2a5faa6a17d4e9676724f204082 937 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 51 62 4.7E-33 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MC49_RS07605 3600d2a5faa6a17d4e9676724f204082 937 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 526 539 4.7E-33 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MC49_RS07605 3600d2a5faa6a17d4e9676724f204082 937 Gene3D G3DSA:1.10.730.10 591 794 5.7E-46 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS07605 3600d2a5faa6a17d4e9676724f204082 937 Gene3D G3DSA:3.40.50.620 387 590 8.0E-53 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS07605 3600d2a5faa6a17d4e9676724f204082 937 SUPERFAMILY SSF50677 205 403 1.99E-55 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MC49_RS07605 3600d2a5faa6a17d4e9676724f204082 937 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 2 928 21.509 T 29-03-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 MC49_RS07605 3600d2a5faa6a17d4e9676724f204082 937 SUPERFAMILY SSF47323 652 928 4.67E-77 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS07605 3600d2a5faa6a17d4e9676724f204082 937 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 58 69 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS07605 3600d2a5faa6a17d4e9676724f204082 937 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 15 843 1.2E-298 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MC49_RS07605 3600d2a5faa6a17d4e9676724f204082 937 Pfam PF06827 Zinc finger found in FPG and IleRS 897 925 4.0E-10 T 29-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 MC49_RS07605 3600d2a5faa6a17d4e9676724f204082 937 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 28 640 1.1E-223 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS07605 3600d2a5faa6a17d4e9676724f204082 937 Gene3D G3DSA:3.40.50.620 42 123 3.6E-27 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS07605 3600d2a5faa6a17d4e9676724f204082 937 Gene3D G3DSA:3.90.740.10 189 386 1.9E-56 T 29-03-2018 MC49_RS07605 3600d2a5faa6a17d4e9676724f204082 937 Gene3D G3DSA:3.30.2320.20 801 895 4.8E-26 T 29-03-2018 MC49_RS07605 3600d2a5faa6a17d4e9676724f204082 937 Pfam PF08264 Anticodon-binding domain of tRNA 685 840 7.0E-27 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 MC49_RS18700 bb85781a0b527136d92a780249f00d12 334 SUPERFAMILY SSF47413 2 58 9.57E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS18700 bb85781a0b527136d92a780249f00d12 334 SMART SM00354 1 73 7.4E-32 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MC49_RS18700 bb85781a0b527136d92a780249f00d12 334 Gene3D G3DSA:3.40.50.2300 169 334 6.2E-23 T 29-03-2018 MC49_RS18700 bb85781a0b527136d92a780249f00d12 334 Gene3D G3DSA:3.40.50.2300 57 168 2.7E-26 T 29-03-2018 MC49_RS18700 bb85781a0b527136d92a780249f00d12 334 SUPERFAMILY SSF53822 60 314 1.67E-43 T 29-03-2018 IPR028082 Periplasmic binding protein-like I MC49_RS18700 bb85781a0b527136d92a780249f00d12 334 Gene3D G3DSA:1.10.260.40 1 56 7.6E-20 T 29-03-2018 MC49_RS18700 bb85781a0b527136d92a780249f00d12 334 TIGRFAM TIGR02417 fruct_sucro_rep: D-fructose-responsive transcription factor 2 328 8.7E-145 T 29-03-2018 IPR012781 D-fructose-responsive transcription factor GO:0003677|GO:0006355|GO:0009750 MC49_RS18700 bb85781a0b527136d92a780249f00d12 334 Pfam PF00356 Bacterial regulatory proteins, lacI family 2 50 4.9E-19 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MC49_RS18700 bb85781a0b527136d92a780249f00d12 334 ProSitePatterns PS00356 LacI-type HTH domain signature. 3 21 - T 29-03-2018 MC49_RS18700 bb85781a0b527136d92a780249f00d12 334 Pfam PF13407 Periplasmic binding protein domain 64 310 2.5E-13 T 29-03-2018 IPR025997 Periplasmic binding protein MC49_RS15765 bbcd99cf7d615b32ab9f2c3a22d5a1ba 457 Pfam PF01554 MatE 244 405 4.1E-38 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MC49_RS15765 bbcd99cf7d615b32ab9f2c3a22d5a1ba 457 Pfam PF01554 MatE 17 177 4.1E-35 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MC49_RS15765 bbcd99cf7d615b32ab9f2c3a22d5a1ba 457 TIGRFAM TIGR00797 matE: MATE efflux family protein 17 422 5.8E-115 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MC49_RS15765 bbcd99cf7d615b32ab9f2c3a22d5a1ba 457 PIRSF PIRSF006603 3 450 2.7E-59 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MC49_RS15765 bbcd99cf7d615b32ab9f2c3a22d5a1ba 457 Hamap MF_00400 Multidrug resistance protein MdtK [mdtK]. 1 457 50.599 T 29-03-2018 IPR022913 Multidrug resistance protein MdtK MC49_RS12440 6502de8e32eee95c03c215a199585021 165 SUPERFAMILY SSF50341 15 158 5.49E-39 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MC49_RS12440 6502de8e32eee95c03c215a199585021 165 Gene3D G3DSA:2.40.50.180 36 99 1.8E-19 T 29-03-2018 MC49_RS12440 6502de8e32eee95c03c215a199585021 165 Gene3D G3DSA:2.30.30.40 100 146 9.5E-16 T 29-03-2018 MC49_RS12440 6502de8e32eee95c03c215a199585021 165 SMART SM00260 15 152 5.8E-40 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MC49_RS12440 6502de8e32eee95c03c215a199585021 165 Pfam PF01584 CheW-like domain 20 155 1.1E-35 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MC49_RS06050 34010a18e4deaf324bae7e56e66395ea 693 SUPERFAMILY SSF52540 508 653 8.68E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS06050 34010a18e4deaf324bae7e56e66395ea 693 SUPERFAMILY SSF52540 292 342 8.68E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS06050 34010a18e4deaf324bae7e56e66395ea 693 SMART SM00487 265 459 6.0E-31 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MC49_RS06050 34010a18e4deaf324bae7e56e66395ea 693 Pfam PF00270 DEAD/DEAH box helicase 273 433 3.0E-18 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MC49_RS06050 34010a18e4deaf324bae7e56e66395ea 693 SUPERFAMILY SSF52540 216 453 1.03E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS06050 34010a18e4deaf324bae7e56e66395ea 693 Gene3D G3DSA:2.40.50.140 53 144 7.6E-12 T 29-03-2018 MC49_RS06050 34010a18e4deaf324bae7e56e66395ea 693 SUPERFAMILY SSF50249 9 176 1.16E-39 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS06050 34010a18e4deaf324bae7e56e66395ea 693 Gene3D G3DSA:3.40.50.300 457 630 2.7E-26 T 29-03-2018 MC49_RS06050 34010a18e4deaf324bae7e56e66395ea 693 Gene3D G3DSA:1.10.150.20 3 52 0.0035 T 29-03-2018 MC49_RS06050 34010a18e4deaf324bae7e56e66395ea 693 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 28 664 3.6E-242 T 29-03-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 MC49_RS06050 34010a18e4deaf324bae7e56e66395ea 693 Pfam PF17191 RecG wedge domain 14 172 3.2E-17 T 29-03-2018 IPR033454 RecG, wedge domain MC49_RS06050 34010a18e4deaf324bae7e56e66395ea 693 Pfam PF00271 Helicase conserved C-terminal domain 480 588 5.6E-18 T 29-03-2018 IPR001650 Helicase, C-terminal MC49_RS06050 34010a18e4deaf324bae7e56e66395ea 693 SMART SM00490 509 589 3.9E-21 T 29-03-2018 IPR001650 Helicase, C-terminal MC49_RS06050 34010a18e4deaf324bae7e56e66395ea 693 Gene3D G3DSA:3.40.50.300 251 456 6.6E-37 T 29-03-2018 MC49_RS17215 5e82227a835f5499adae0378c7590524 362 TIGRFAM TIGR00698 TIGR00698: conserved hypothetical protein 23 358 2.6E-126 T 29-03-2018 IPR004630 Uncharacterised protein family UPF0324, bacteria GO:0016021 MC49_RS17215 5e82227a835f5499adae0378c7590524 362 Pfam PF03601 Conserved hypothetical protein 698 24 339 2.3E-106 T 29-03-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 MC49_RS11345 45c107c0c1a022e1d9fb8aacdf58f792 105 SUPERFAMILY SSF141255 4 96 1.44E-27 T 29-03-2018 IPR011722 Hemimethylated DNA-binding domain GO:0003677 MC49_RS11345 45c107c0c1a022e1d9fb8aacdf58f792 105 TIGRFAM TIGR02097 yccV: hemimethylated DNA binding domain 4 102 1.6E-29 T 29-03-2018 IPR011722 Hemimethylated DNA-binding domain GO:0003677 MC49_RS11345 45c107c0c1a022e1d9fb8aacdf58f792 105 Hamap MF_01194 Heat shock protein HspQ [hspQ]. 1 105 35.505 T 29-03-2018 IPR022866 Heat shock protein HspQ MC49_RS11345 45c107c0c1a022e1d9fb8aacdf58f792 105 Pfam PF08755 Hemimethylated DNA-binding protein YccV like 5 96 4.0E-19 T 29-03-2018 IPR011722 Hemimethylated DNA-binding domain GO:0003677 MC49_RS11345 45c107c0c1a022e1d9fb8aacdf58f792 105 Gene3D G3DSA:2.30.30.390 1 105 3.7E-19 T 29-03-2018 IPR011722 Hemimethylated DNA-binding domain GO:0003677 MC49_RS11345 45c107c0c1a022e1d9fb8aacdf58f792 105 SMART SM00992 3 102 2.7E-31 T 29-03-2018 IPR011722 Hemimethylated DNA-binding domain GO:0003677 MC49_RS02480 f0b90cd3c2758460a9ff9b0045250ef0 667 SUPERFAMILY SSF55874 514 661 1.7E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS02480 f0b90cd3c2758460a9ff9b0045250ef0 667 Gene3D G3DSA:3.30.565.10 478 660 7.8E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS02480 f0b90cd3c2758460a9ff9b0045250ef0 667 PIRSF PIRSF037119 5 412 2.0E-99 T 29-03-2018 IPR017116 Signal transduction histidine kinase, PgtB MC49_RS02480 f0b90cd3c2758460a9ff9b0045250ef0 667 PIRSF PIRSF037119 404 666 7.9E-96 T 29-03-2018 IPR017116 Signal transduction histidine kinase, PgtB MC49_RS02480 f0b90cd3c2758460a9ff9b0045250ef0 667 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 558 661 4.1E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS02480 f0b90cd3c2758460a9ff9b0045250ef0 667 SUPERFAMILY SSF158472 367 412 6.15E-5 T 29-03-2018 MC49_RS02480 f0b90cd3c2758460a9ff9b0045250ef0 667 SMART SM00304 365 417 1.5E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MC49_RS02480 f0b90cd3c2758460a9ff9b0045250ef0 667 SMART SM00388 448 516 4.1E-5 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS02480 f0b90cd3c2758460a9ff9b0045250ef0 667 Pfam PF00672 HAMP domain 366 410 1.2E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MC49_RS02480 f0b90cd3c2758460a9ff9b0045250ef0 667 SUPERFAMILY SSF47384 444 514 5.1E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS02480 f0b90cd3c2758460a9ff9b0045250ef0 667 PRINTS PR00344 Bacterial sensor protein C-terminal signature 613 623 1.6E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS02480 f0b90cd3c2758460a9ff9b0045250ef0 667 PRINTS PR00344 Bacterial sensor protein C-terminal signature 595 609 1.6E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS02480 f0b90cd3c2758460a9ff9b0045250ef0 667 PRINTS PR00344 Bacterial sensor protein C-terminal signature 624 642 1.6E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS02480 f0b90cd3c2758460a9ff9b0045250ef0 667 Gene3D G3DSA:3.30.450.20 214 477 1.9E-4 T 29-03-2018 MC49_RS02480 f0b90cd3c2758460a9ff9b0045250ef0 667 SMART SM00387 558 664 1.3E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS02480 f0b90cd3c2758460a9ff9b0045250ef0 667 Pfam PF00512 His Kinase A (phospho-acceptor) domain 450 513 1.1E-7 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS04540 da0c7ed4fcb12f5b52db8cf4e3aa2c19 320 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 259 272 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MC49_RS04540 da0c7ed4fcb12f5b52db8cf4e3aa2c19 320 SUPERFAMILY SSF53613 4 306 3.43E-70 T 29-03-2018 IPR029056 Ribokinase-like MC49_RS04540 da0c7ed4fcb12f5b52db8cf4e3aa2c19 320 Gene3D G3DSA:3.40.1190.20 2 317 1.6E-54 T 29-03-2018 IPR029056 Ribokinase-like MC49_RS04540 da0c7ed4fcb12f5b52db8cf4e3aa2c19 320 Pfam PF00294 pfkB family carbohydrate kinase 7 304 1.4E-65 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB MC49_RS18890 e717a7ad1de28c1a507e4384ce44c4c0 335 SUPERFAMILY SSF63380 11 105 3.1E-20 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MC49_RS18890 e717a7ad1de28c1a507e4384ce44c4c0 335 PRINTS PR00406 Cytochrome B5 reductase signature 207 215 1.8E-6 T 29-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 MC49_RS18890 e717a7ad1de28c1a507e4384ce44c4c0 335 PRINTS PR00406 Cytochrome B5 reductase signature 115 134 1.8E-6 T 29-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 MC49_RS18890 e717a7ad1de28c1a507e4384ce44c4c0 335 PRINTS PR00406 Cytochrome B5 reductase signature 55 62 1.8E-6 T 29-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 MC49_RS18890 e717a7ad1de28c1a507e4384ce44c4c0 335 Gene3D G3DSA:3.10.20.30 237 335 4.2E-23 T 29-03-2018 IPR012675 Beta-grasp domain MC49_RS18890 e717a7ad1de28c1a507e4384ce44c4c0 335 Gene3D G3DSA:2.40.30.10 9 105 2.5E-16 T 29-03-2018 MC49_RS18890 e717a7ad1de28c1a507e4384ce44c4c0 335 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 261 328 2.5E-13 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MC49_RS18890 e717a7ad1de28c1a507e4384ce44c4c0 335 Gene3D G3DSA:3.40.50.80 106 236 1.2E-26 T 29-03-2018 MC49_RS18890 e717a7ad1de28c1a507e4384ce44c4c0 335 Pfam PF00970 Oxidoreductase FAD-binding domain 34 104 6.0E-7 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 MC49_RS18890 e717a7ad1de28c1a507e4384ce44c4c0 335 SUPERFAMILY SSF54292 230 334 5.24E-26 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MC49_RS18890 e717a7ad1de28c1a507e4384ce44c4c0 335 SUPERFAMILY SSF52343 110 241 5.5E-32 T 29-03-2018 MC49_RS18890 e717a7ad1de28c1a507e4384ce44c4c0 335 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 286 294 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MC49_RS18890 e717a7ad1de28c1a507e4384ce44c4c0 335 Pfam PF00175 Oxidoreductase NAD-binding domain 116 221 1.3E-15 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MC49_RS01320 e1e30ad7b8d3fc61e98edcb4fdaa43cb 327 Gene3D G3DSA:3.30.70.20 168 304 2.4E-14 T 29-03-2018 MC49_RS01320 e1e30ad7b8d3fc61e98edcb4fdaa43cb 327 Gene3D G3DSA:3.30.70.20 51 126 2.1E-15 T 29-03-2018 MC49_RS01320 e1e30ad7b8d3fc61e98edcb4fdaa43cb 327 Gene3D G3DSA:3.30.70.20 127 167 1.2E-16 T 29-03-2018 MC49_RS01320 e1e30ad7b8d3fc61e98edcb4fdaa43cb 327 Gene3D G3DSA:3.30.70.20 28 50 0.032 T 29-03-2018 MC49_RS01320 e1e30ad7b8d3fc61e98edcb4fdaa43cb 327 Pfam PF13247 4Fe-4S dicluster domain 105 206 8.0E-22 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MC49_RS01320 e1e30ad7b8d3fc61e98edcb4fdaa43cb 327 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 144 155 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MC49_RS01320 e1e30ad7b8d3fc61e98edcb4fdaa43cb 327 SUPERFAMILY SSF54862 38 323 1.74E-68 T 29-03-2018 MC49_RS16935 1bd81b4cdb8426c7c93ce6c6b1f037f7 154 SUPERFAMILY SSF55811 2 125 1.62E-28 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MC49_RS16935 1bd81b4cdb8426c7c93ce6c6b1f037f7 154 PRINTS PR00502 NUDIX hydrolase family signature 31 45 3.7E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MC49_RS16935 1bd81b4cdb8426c7c93ce6c6b1f037f7 154 PRINTS PR00502 NUDIX hydrolase family signature 45 60 3.7E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MC49_RS16935 1bd81b4cdb8426c7c93ce6c6b1f037f7 154 ProSitePatterns PS00893 Nudix box signature. 36 57 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MC49_RS16935 1bd81b4cdb8426c7c93ce6c6b1f037f7 154 Gene3D G3DSA:3.90.79.10 1 135 2.4E-28 T 29-03-2018 MC49_RS16935 1bd81b4cdb8426c7c93ce6c6b1f037f7 154 Pfam PF00293 NUDIX domain 4 118 6.3E-18 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MC49_RS12695 e63948f62ed2d00ebbb226acc9fe67e8 481 Pfam PF07196 Flagellin hook IN motif 131 188 2.1E-8 T 29-03-2018 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 MC49_RS12695 e63948f62ed2d00ebbb226acc9fe67e8 481 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 236 469 1.9E-57 T 29-03-2018 IPR010809 Flagellar hook-associated 2, C-terminal GO:0007155|GO:0009288 MC49_RS12695 e63948f62ed2d00ebbb226acc9fe67e8 481 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 12 106 2.3E-16 T 29-03-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 MC49_RS12695 e63948f62ed2d00ebbb226acc9fe67e8 481 Gene3D G3DSA:1.20.5.50 408 478 4.4E-5 T 29-03-2018 MC49_RS05875 9a38aa7b0a0eb002cd3eeb577ae15bd0 342 SUPERFAMILY SSF47413 10 67 1.31E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS05875 9a38aa7b0a0eb002cd3eeb577ae15bd0 342 Gene3D G3DSA:3.40.50.2300 183 339 6.8E-46 T 29-03-2018 MC49_RS05875 9a38aa7b0a0eb002cd3eeb577ae15bd0 342 Gene3D G3DSA:1.10.10.60 4 22 0.0021 T 29-03-2018 MC49_RS05875 9a38aa7b0a0eb002cd3eeb577ae15bd0 342 Gene3D G3DSA:3.40.50.2300 63 182 6.5E-27 T 29-03-2018 MC49_RS05875 9a38aa7b0a0eb002cd3eeb577ae15bd0 342 Pfam PF00356 Bacterial regulatory proteins, lacI family 11 55 2.8E-19 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MC49_RS05875 9a38aa7b0a0eb002cd3eeb577ae15bd0 342 SMART SM00354 9 79 1.7E-26 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MC49_RS05875 9a38aa7b0a0eb002cd3eeb577ae15bd0 342 Pfam PF13377 Periplasmic binding protein-like domain 177 336 3.5E-39 T 29-03-2018 MC49_RS05875 9a38aa7b0a0eb002cd3eeb577ae15bd0 342 SUPERFAMILY SSF53822 68 340 7.07E-88 T 29-03-2018 IPR028082 Periplasmic binding protein-like I MC49_RS05875 9a38aa7b0a0eb002cd3eeb577ae15bd0 342 Gene3D G3DSA:1.10.260.40 23 62 2.3E-18 T 29-03-2018 MC49_RS18360 4ffdc7bb17cdddfafe4a2a633b4c8f42 720 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 576 704 1.0E-47 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 MC49_RS18360 4ffdc7bb17cdddfafe4a2a633b4c8f42 720 Gene3D G3DSA:3.40.640.10 109 420 8.4E-33 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS18360 4ffdc7bb17cdddfafe4a2a633b4c8f42 720 SUPERFAMILY SSF53383 109 567 1.37E-119 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS18360 4ffdc7bb17cdddfafe4a2a633b4c8f42 720 Gene3D G3DSA:3.90.100.10 601 720 9.6E-35 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 MC49_RS18360 4ffdc7bb17cdddfafe4a2a633b4c8f42 720 PIRSF PIRSF009393 2 720 1.6E-290 T 29-03-2018 IPR011193 Ornithine/lysine/arginine decarboxylase GO:0005737|GO:0006520|GO:0016831 MC49_RS18360 4ffdc7bb17cdddfafe4a2a633b4c8f42 720 Gene3D G3DSA:3.90.1150.10 421 600 1.6E-51 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS18360 4ffdc7bb17cdddfafe4a2a633b4c8f42 720 TIGRFAM TIGR04301 ODC_inducible: ornithine decarboxylase SpeF 1 719 0.0 T 29-03-2018 IPR027568 Ornithine decarboxylase SpeF GO:0004586 KEGG: 00330+4.1.1.17|KEGG: 00480+4.1.1.17|MetaCyc: PWY-46|MetaCyc: PWY-6305 MC49_RS18360 4ffdc7bb17cdddfafe4a2a633b4c8f42 720 SUPERFAMILY SSF55904 571 719 3.53E-47 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 MC49_RS18360 4ffdc7bb17cdddfafe4a2a633b4c8f42 720 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 350 364 - T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 MC49_RS18360 4ffdc7bb17cdddfafe4a2a633b4c8f42 720 SUPERFAMILY SSF52172 1 108 1.14E-31 T 29-03-2018 IPR011006 CheY-like superfamily MC49_RS18360 4ffdc7bb17cdddfafe4a2a633b4c8f42 720 Pfam PF03709 Orn/Lys/Arg decarboxylase, N-terminal domain 4 103 4.1E-19 T 29-03-2018 IPR005308 Orn/Lys/Arg decarboxylase, N-terminal GO:0016831 MC49_RS18360 4ffdc7bb17cdddfafe4a2a633b4c8f42 720 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 109 551 2.1E-197 T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 MC49_RS18360 4ffdc7bb17cdddfafe4a2a633b4c8f42 720 Gene3D G3DSA:3.40.50.220 3 108 3.5E-33 T 29-03-2018 IPR027464 Ornithine decarboxylase, N-terminal domain KEGG: 00330+4.1.1.17|KEGG: 00480+4.1.1.17|MetaCyc: PWY-46|MetaCyc: PWY-6305 MC49_RS03025 b2b9117a45457486daf0e161c04d0237 163 Pfam PF00419 Fimbrial protein 40 163 8.7E-13 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS03025 b2b9117a45457486daf0e161c04d0237 163 Gene3D G3DSA:2.60.40.1090 42 163 5.1E-13 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS03025 b2b9117a45457486daf0e161c04d0237 163 SUPERFAMILY SSF49401 40 163 6.46E-18 T 29-03-2018 IPR008966 Adhesion domain MC49_RS15135 a79e39f5e394e374fca3424254aee151 310 Pfam PF00849 RNA pseudouridylate synthase 72 204 1.0E-16 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS15135 a79e39f5e394e374fca3424254aee151 310 SUPERFAMILY SSF55174 8 101 1.91E-9 T 29-03-2018 MC49_RS15135 a79e39f5e394e374fca3424254aee151 310 SMART SM00363 6 77 1.3E-5 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MC49_RS15135 a79e39f5e394e374fca3424254aee151 310 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 110 124 - T 29-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 MC49_RS15135 a79e39f5e394e374fca3424254aee151 310 Gene3D G3DSA:3.10.290.10 3 67 3.1E-12 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MC49_RS15135 a79e39f5e394e374fca3424254aee151 310 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 76 236 7.4E-61 T 29-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 MC49_RS15135 a79e39f5e394e374fca3424254aee151 310 Pfam PF01479 S4 domain 7 48 7.1E-9 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MC49_RS15135 a79e39f5e394e374fca3424254aee151 310 Gene3D G3DSA:3.30.70.580 68 153 1.1E-18 T 29-03-2018 MC49_RS15135 a79e39f5e394e374fca3424254aee151 310 Gene3D G3DSA:3.30.70.1560 154 222 1.2E-21 T 29-03-2018 MC49_RS15135 a79e39f5e394e374fca3424254aee151 310 SUPERFAMILY SSF55120 71 238 8.0E-44 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS04505 bc051ad492a8ff98f983f7882cbaf8bd 393 Gene3D G3DSA:3.40.47.10 266 390 1.5E-36 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MC49_RS04505 bc051ad492a8ff98f983f7882cbaf8bd 393 PIRSF PIRSF000429 1 393 3.2E-136 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MC49_RS04505 bc051ad492a8ff98f983f7882cbaf8bd 393 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 391 8.4E-152 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MC49_RS04505 bc051ad492a8ff98f983f7882cbaf8bd 393 ProSitePatterns PS00737 Thiolases signature 2. 339 355 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 MC49_RS04505 bc051ad492a8ff98f983f7882cbaf8bd 393 SUPERFAMILY SSF53901 271 392 2.81E-46 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MC49_RS04505 bc051ad492a8ff98f983f7882cbaf8bd 393 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 MC49_RS04505 bc051ad492a8ff98f983f7882cbaf8bd 393 Pfam PF02803 Thiolase, C-terminal domain 270 392 5.2E-53 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 MC49_RS04505 bc051ad492a8ff98f983f7882cbaf8bd 393 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 MC49_RS04505 bc051ad492a8ff98f983f7882cbaf8bd 393 SUPERFAMILY SSF53901 4 269 3.85E-88 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MC49_RS04505 bc051ad492a8ff98f983f7882cbaf8bd 393 Gene3D G3DSA:3.40.47.10 1 184 9.7E-39 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MC49_RS04505 bc051ad492a8ff98f983f7882cbaf8bd 393 Gene3D G3DSA:3.40.47.10 185 265 1.4E-25 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MC49_RS04505 bc051ad492a8ff98f983f7882cbaf8bd 393 Pfam PF00108 Thiolase, N-terminal domain 4 262 4.8E-106 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 MC49_RS08145 09e2147be7d48f68f8eacb84facb1afe 271 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 14 271 1.4E-143 T 29-03-2018 IPR004872 Lipoprotein NlpA family MC49_RS08145 09e2147be7d48f68f8eacb84facb1afe 271 Gene3D G3DSA:3.40.190.10 127 271 2.7E-49 T 29-03-2018 MC49_RS08145 09e2147be7d48f68f8eacb84facb1afe 271 SUPERFAMILY SSF53850 32 271 4.9E-84 T 29-03-2018 MC49_RS08145 09e2147be7d48f68f8eacb84facb1afe 271 Gene3D G3DSA:3.40.190.10 32 126 9.4E-22 T 29-03-2018 MC49_RS08145 09e2147be7d48f68f8eacb84facb1afe 271 PIRSF PIRSF002854 1 271 9.5E-105 T 29-03-2018 IPR004872 Lipoprotein NlpA family MC49_RS08145 09e2147be7d48f68f8eacb84facb1afe 271 Pfam PF03180 NLPA lipoprotein 33 271 1.9E-98 T 29-03-2018 IPR004872 Lipoprotein NlpA family MC49_RS17335 fcc3567be6997ceb40896c67187f9e3d 242 Pfam PF01925 Sulfite exporter TauE/SafE 2 236 1.4E-36 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MC49_RS11605 313f4f5b3080060e64d231775bb1c2ad 103 SUPERFAMILY SSF55729 7 67 4.72E-7 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS11605 313f4f5b3080060e64d231775bb1c2ad 103 Gene3D G3DSA:3.40.630.30 3 100 3.6E-7 T 29-03-2018 MC49_RS11605 313f4f5b3080060e64d231775bb1c2ad 103 Pfam PF17274 Family of unknown function (DUF5339) 68 98 1.3E-6 T 29-03-2018 IPR020493 Uncharacterised protein family HI0310 MC49_RS01360 ea77a2b8da8b0d437484363749065622 137 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 17 127 2.2E-20 T 29-03-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III MC49_RS16030 f058b021ceeb9fbb2150ba5bc10c9ff2 221 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 126 191 4.4E-13 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MC49_RS16030 f058b021ceeb9fbb2150ba5bc10c9ff2 221 Pfam PF13419 Haloacid dehalogenase-like hydrolase 11 191 1.2E-27 T 29-03-2018 IPR023214 HAD-like domain MC49_RS16030 f058b021ceeb9fbb2150ba5bc10c9ff2 221 Gene3D G3DSA:1.10.150.240 20 78 5.8E-16 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 MC49_RS16030 f058b021ceeb9fbb2150ba5bc10c9ff2 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 104 117 1.7E-9 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MC49_RS16030 f058b021ceeb9fbb2150ba5bc10c9ff2 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 153 173 1.7E-9 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MC49_RS16030 f058b021ceeb9fbb2150ba5bc10c9ff2 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 7 18 1.7E-9 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MC49_RS16030 f058b021ceeb9fbb2150ba5bc10c9ff2 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 135 151 1.7E-9 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MC49_RS16030 f058b021ceeb9fbb2150ba5bc10c9ff2 221 Gene3D G3DSA:3.40.50.1000 79 221 8.7E-31 T 29-03-2018 IPR023214 HAD-like domain MC49_RS16030 f058b021ceeb9fbb2150ba5bc10c9ff2 221 SUPERFAMILY SSF56784 7 218 1.35E-52 T 29-03-2018 IPR023214 HAD-like domain MC49_RS11255 e24d567d602161a0e7fe85d074a16e56 181 PIRSF PIRSF010252 1 177 1.7E-55 T 29-03-2018 IPR009809 Cell division protein ZapC MC49_RS11255 e24d567d602161a0e7fe85d074a16e56 181 Pfam PF07126 Cell-division protein ZapC 2 168 4.7E-65 T 29-03-2018 IPR009809 Cell division protein ZapC MC49_RS11255 e24d567d602161a0e7fe85d074a16e56 181 Hamap MF_00906 Cell division protein ZapC [zapC]. 2 176 35.795 T 29-03-2018 IPR009809 Cell division protein ZapC MC49_RS02505 fef0ea00381a7303685866eab6253ea4 151 Pfam PF02631 RecX family 42 149 3.9E-26 T 29-03-2018 IPR003783 Regulatory protein RecX GO:0006282 MC49_RS02505 fef0ea00381a7303685866eab6253ea4 151 Gene3D G3DSA:1.10.10.10 106 151 4.2E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS02505 fef0ea00381a7303685866eab6253ea4 151 Gene3D G3DSA:1.10.10.10 60 104 1.4E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS02505 fef0ea00381a7303685866eab6253ea4 151 Gene3D G3DSA:1.10.10.10 4 59 6.2E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS02505 fef0ea00381a7303685866eab6253ea4 151 Hamap MF_01114 Regulatory protein RecX [recX]. 1 150 11.551 T 29-03-2018 IPR003783 Regulatory protein RecX GO:0006282 MC49_RS11565 72eb6427247cff9e42ef53e6eb5bf345 114 PIRSF PIRSF021239 1 113 7.2E-47 T 29-03-2018 IPR007437 Putative member of DMT superfamily MC49_RS11565 72eb6427247cff9e42ef53e6eb5bf345 114 Pfam PF04342 Putative member of DMT superfamily (DUF486) 8 110 1.3E-43 T 29-03-2018 IPR007437 Putative member of DMT superfamily MC49_RS06105 3049ad25f95afa51bdaa4d61486d18a4 689 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 6 551 4.4E-211 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MC49_RS06105 3049ad25f95afa51bdaa4d61486d18a4 689 Pfam PF05746 DALR anticodon binding domain 582 678 1.5E-8 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 MC49_RS06105 3049ad25f95afa51bdaa4d61486d18a4 689 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 7 20 2.1E-36 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MC49_RS06105 3049ad25f95afa51bdaa4d61486d18a4 689 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 318 334 2.1E-36 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MC49_RS06105 3049ad25f95afa51bdaa4d61486d18a4 689 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 394 413 2.1E-36 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MC49_RS06105 3049ad25f95afa51bdaa4d61486d18a4 689 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 50 62 2.1E-36 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MC49_RS06105 3049ad25f95afa51bdaa4d61486d18a4 689 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 246 261 2.1E-36 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MC49_RS06105 3049ad25f95afa51bdaa4d61486d18a4 689 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 3 688 26.392 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MC49_RS06105 3049ad25f95afa51bdaa4d61486d18a4 689 SUPERFAMILY SSF109604 340 499 7.95E-15 T 29-03-2018 MC49_RS06105 3049ad25f95afa51bdaa4d61486d18a4 689 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 1 689 0.0 T 29-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MC49_RS06105 3049ad25f95afa51bdaa4d61486d18a4 689 SMART SM00836 585 688 0.0051 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 MC49_RS06105 3049ad25f95afa51bdaa4d61486d18a4 689 Gene3D G3DSA:1.10.730.10 574 683 3.6E-11 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS09500 8f54f5eadd12e8436827e52a33f67ed8 201 Pfam PF00030 Beta/Gamma crystallin 121 181 5.4E-6 T 29-03-2018 IPR001064 Beta/gamma crystallin MC49_RS09500 8f54f5eadd12e8436827e52a33f67ed8 201 Gene3D G3DSA:2.60.20.10 67 199 6.7E-12 T 29-03-2018 MC49_RS09500 8f54f5eadd12e8436827e52a33f67ed8 201 SUPERFAMILY SSF49695 120 199 1.71E-10 T 29-03-2018 IPR011024 Gamma-crystallin-related MC49_RS10100 8aa2fb5a10bb1d5dbd71893aba88abe5 329 SUPERFAMILY SSF110997 258 327 1.7E-13 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 MC49_RS10100 8aa2fb5a10bb1d5dbd71893aba88abe5 329 Gene3D G3DSA:3.30.70.1070 258 329 2.2E-13 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 MC49_RS10100 8aa2fb5a10bb1d5dbd71893aba88abe5 329 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 75 175 6.3E-25 T 29-03-2018 IPR012997 Rare lipoprotein A MC49_RS10100 8aa2fb5a10bb1d5dbd71893aba88abe5 329 Pfam PF03330 Lytic transglycolase 73 159 1.6E-13 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain MC49_RS10100 8aa2fb5a10bb1d5dbd71893aba88abe5 329 Pfam PF05036 Sporulation related domain 257 327 7.1E-14 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 MC49_RS10100 8aa2fb5a10bb1d5dbd71893aba88abe5 329 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 10 163 18.023 T 29-03-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 MC49_RS10100 8aa2fb5a10bb1d5dbd71893aba88abe5 329 Gene3D G3DSA:2.40.40.10 52 161 1.6E-10 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain MC49_RS06670 708dbc63e7eba3616c13ac6b371c8a83 80 SUPERFAMILY SSF47413 9 75 9.38E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS06670 708dbc63e7eba3616c13ac6b371c8a83 80 SMART SM00530 16 71 2.5E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS06670 708dbc63e7eba3616c13ac6b371c8a83 80 Pfam PF01381 Helix-turn-helix 21 71 2.3E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS06670 708dbc63e7eba3616c13ac6b371c8a83 80 Gene3D G3DSA:1.10.3100.10 7 79 3.7E-15 T 29-03-2018 IPR027910 YdiL-like domain MC49_RS01915 44b0775752af1e474bac3daee5bc0b5b 398 Pfam PF02754 Cysteine-rich domain 165 251 2.3E-14 T 29-03-2018 IPR004017 Cysteine-rich domain MC49_RS01915 44b0775752af1e474bac3daee5bc0b5b 398 Pfam PF02754 Cysteine-rich domain 295 378 2.5E-12 T 29-03-2018 IPR004017 Cysteine-rich domain MC49_RS01915 44b0775752af1e474bac3daee5bc0b5b 398 Pfam PF13183 4Fe-4S dicluster domain 8 72 7.3E-10 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MC49_RS01915 44b0775752af1e474bac3daee5bc0b5b 398 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 58 69 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MC49_RS01915 44b0775752af1e474bac3daee5bc0b5b 398 Gene3D G3DSA:3.30.70.20 67 388 0.0023 T 29-03-2018 MC49_RS01915 44b0775752af1e474bac3daee5bc0b5b 398 SUPERFAMILY SSF46548 7 82 6.8E-16 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MC49_RS01915 44b0775752af1e474bac3daee5bc0b5b 398 Gene3D G3DSA:3.30.70.20 5 66 2.4E-8 T 29-03-2018 MC49_RS01915 44b0775752af1e474bac3daee5bc0b5b 398 TIGRFAM TIGR03379 glycerol3P_GlpC: glycerol-3-phosphate dehydrogenase, anaerobic, C subunit 6 397 2.2E-221 T 29-03-2018 IPR017753 Glycerol-3-phosphate dehydrogenase, GlpC subunit GO:0006810|GO:0016020 MC49_RS13445 d6000f82033de92fcd8520141c186ce1 198 Pfam PF06940 Domain of unknown function (DUF1287) 29 193 5.8E-64 T 29-03-2018 IPR009706 Protein of unknown function DUF1287 MC49_RS13445 d6000f82033de92fcd8520141c186ce1 198 PIRSF PIRSF011444 11 196 8.0E-72 T 29-03-2018 IPR009706 Protein of unknown function DUF1287 MC49_RS13445 d6000f82033de92fcd8520141c186ce1 198 ProDom PD357862 YIJF PERIPLASMIC ECS4873 PRECURSOR CC1379 SIGNAL DOMAIN PM0035 19 193 1.0E-50 T 29-03-2018 IPR009706 Protein of unknown function DUF1287 MC49_RS13445 d6000f82033de92fcd8520141c186ce1 198 Gene3D G3DSA:3.90.1720.10 23 198 5.1E-10 T 29-03-2018 MC49_RS00720 53d1ff17ce8bb75ba2ae070aed3906bf 136 Gene3D G3DSA:3.10.129.10 1 136 7.8E-34 T 29-03-2018 MC49_RS00720 53d1ff17ce8bb75ba2ae070aed3906bf 136 SUPERFAMILY SSF54637 2 128 5.53E-36 T 29-03-2018 IPR029069 HotDog domain MC49_RS00720 53d1ff17ce8bb75ba2ae070aed3906bf 136 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 8 119 5.6E-25 T 29-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 MC49_RS00720 53d1ff17ce8bb75ba2ae070aed3906bf 136 Pfam PF13279 Thioesterase-like superfamily 12 126 8.7E-18 T 29-03-2018 MC49_RS00720 53d1ff17ce8bb75ba2ae070aed3906bf 136 PIRSF PIRSF003230 1 134 1.4E-23 T 29-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 MC49_RS02435 a66342f2aff5722ddcb493c25e232875 178 SUPERFAMILY SSF49401 54 178 5.47E-22 T 29-03-2018 IPR008966 Adhesion domain MC49_RS02435 a66342f2aff5722ddcb493c25e232875 178 Pfam PF00419 Fimbrial protein 46 178 1.0E-14 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS02435 a66342f2aff5722ddcb493c25e232875 178 Gene3D G3DSA:2.60.40.1090 43 178 4.0E-16 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS09115 773d2e966a0314c1d487d8997d66c8eb 114 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 9 113 4.3E-38 T 29-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 MC49_RS09115 773d2e966a0314c1d487d8997d66c8eb 114 Hamap MF_01380 Iron-sulfur cluster insertion protein ErpA [erpA]. 1 114 36.537 T 29-03-2018 IPR023063 FeS cluster insertion protein ErpA GO:0097428 MC49_RS09115 773d2e966a0314c1d487d8997d66c8eb 114 Pfam PF01521 Iron-sulphur cluster biosynthesis 7 109 1.3E-20 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MC49_RS09115 773d2e966a0314c1d487d8997d66c8eb 114 SUPERFAMILY SSF89360 6 100 8.24E-31 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MC49_RS09115 773d2e966a0314c1d487d8997d66c8eb 114 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 95 112 - T 29-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 MC49_RS09115 773d2e966a0314c1d487d8997d66c8eb 114 Gene3D G3DSA:2.60.300.12 8 114 1.2E-37 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MC49_RS03615 5ac8160d43f1bbf7a2302ef8607cd55c 154 SUPERFAMILY SSF52540 25 140 1.93E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS03615 5ac8160d43f1bbf7a2302ef8607cd55c 154 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 9 133 1.3E-40 T 29-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 MC49_RS03615 5ac8160d43f1bbf7a2302ef8607cd55c 154 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 8 139 8.8E-50 T 29-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 MC49_RS03615 5ac8160d43f1bbf7a2302ef8607cd55c 154 Gene3D G3DSA:3.40.50.300 1 153 6.8E-52 T 29-03-2018 MC49_RS08400 65f61fd542078bffb9a6638c52c54b5c 241 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 101 133 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 MC49_RS08400 65f61fd542078bffb9a6638c52c54b5c 241 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 11 217 5.3E-43 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MC49_RS08400 65f61fd542078bffb9a6638c52c54b5c 241 Gene3D G3DSA:3.40.1010.10 9 154 2.9E-24 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MC49_RS08400 65f61fd542078bffb9a6638c52c54b5c 241 SUPERFAMILY SSF53790 4 238 3.01E-41 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MC49_RS08400 65f61fd542078bffb9a6638c52c54b5c 241 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 10 238 5.9E-72 T 29-03-2018 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 MC49_RS08400 65f61fd542078bffb9a6638c52c54b5c 241 PIRSF PIRSF036427 8 241 9.6E-72 T 29-03-2018 IPR012382 Precorrin-2 C(20)-methyltransferase GO:0008757|GO:0009236|GO:0030788 MC49_RS08400 65f61fd542078bffb9a6638c52c54b5c 241 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 15 29 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 MC49_RS08010 f5cfedee48af0bfd9a94a5f761755743 274 Pfam PF14805 Tetrahydrodipicolinate N-succinyltransferase N-terminal 3 69 2.2E-25 T 29-03-2018 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 MC49_RS08010 f5cfedee48af0bfd9a94a5f761755743 274 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 133 166 0.0023 T 29-03-2018 IPR001451 Hexapeptide repeat MC49_RS08010 f5cfedee48af0bfd9a94a5f761755743 274 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 134 162 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MC49_RS08010 f5cfedee48af0bfd9a94a5f761755743 274 Gene3D G3DSA:2.160.10.10 87 257 4.5E-34 T 29-03-2018 MC49_RS08010 f5cfedee48af0bfd9a94a5f761755743 274 Gene3D G3DSA:1.10.166.10 3 69 3.8E-28 T 29-03-2018 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 MC49_RS08010 f5cfedee48af0bfd9a94a5f761755743 274 TIGRFAM TIGR00965 dapD: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 3 273 5.2E-158 T 29-03-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 MC49_RS08010 f5cfedee48af0bfd9a94a5f761755743 274 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 175 209 1.3E-12 T 29-03-2018 IPR001451 Hexapeptide repeat MC49_RS08010 f5cfedee48af0bfd9a94a5f761755743 274 SUPERFAMILY SSF51161 1 256 5.27E-77 T 29-03-2018 IPR011004 Trimeric LpxA-like MC49_RS08010 f5cfedee48af0bfd9a94a5f761755743 274 Hamap MF_00811 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 1 272 58.118 T 29-03-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 MC49_RS02960 b5254efaabcbc963e3be6e61b6e807ce 105 Gene3D G3DSA:3.30.1190.10 60 102 6.8E-14 T 29-03-2018 MC49_RS02960 b5254efaabcbc963e3be6e61b6e807ce 105 SMART SM00530 41 96 7.3E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS02960 b5254efaabcbc963e3be6e61b6e807ce 105 Pfam PF01381 Helix-turn-helix 42 92 5.1E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS02960 b5254efaabcbc963e3be6e61b6e807ce 105 Gene3D G3DSA:1.10.10.10 13 59 4.9E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS02960 b5254efaabcbc963e3be6e61b6e807ce 105 SUPERFAMILY SSF47413 29 95 1.86E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS17520 4750a91cf42d747a8fb67f2352f63957 915 Gene3D G3DSA:1.20.1480.30 443 539 0.065 T 29-03-2018 MC49_RS17520 4750a91cf42d747a8fb67f2352f63957 915 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 199 545 6.0E-90 T 29-03-2018 IPR010090 Phage tail tape measure protein MC49_RS17520 4750a91cf42d747a8fb67f2352f63957 915 Gene3D G3DSA:1.20.120.570 6 144 1.5E-4 T 29-03-2018 MC49_RS17520 4750a91cf42d747a8fb67f2352f63957 915 Pfam PF10145 Phage-related minor tail protein 240 438 1.7E-48 T 29-03-2018 IPR010090 Phage tail tape measure protein MC49_RS17520 4750a91cf42d747a8fb67f2352f63957 915 Gene3D G3DSA:1.20.120.20 610 776 6.1E-15 T 29-03-2018 MC49_RS08455 fa1cf01c74e96ba7be333342708ab931 461 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 10 447 4.0E-142 T 29-03-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 MC49_RS08455 fa1cf01c74e96ba7be333342708ab931 461 Gene3D G3DSA:3.40.50.880 229 418 1.0E-26 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MC49_RS08455 fa1cf01c74e96ba7be333342708ab931 461 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 253 446 1.5E-41 T 29-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 MC49_RS08455 fa1cf01c74e96ba7be333342708ab931 461 Gene3D G3DSA:3.40.50.300 1 185 1.1E-37 T 29-03-2018 MC49_RS08455 fa1cf01c74e96ba7be333342708ab931 461 SUPERFAMILY SSF52317 250 456 7.64E-35 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MC49_RS08455 fa1cf01c74e96ba7be333342708ab931 461 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 10 195 3.5E-21 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain MC49_RS08455 fa1cf01c74e96ba7be333342708ab931 461 Hamap MF_00027 Cobyrinate a,c-diamide synthase [cbiA]. 6 447 44.171 T 29-03-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 MC49_RS08455 fa1cf01c74e96ba7be333342708ab931 461 SUPERFAMILY SSF52540 8 202 1.92E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS10090 2f901b9ab8e258c2b5e413057724063f 87 SUPERFAMILY SSF117991 1 87 5.23E-31 T 29-03-2018 IPR027471 YbeD-like domain MC49_RS10090 2f901b9ab8e258c2b5e413057724063f 87 Gene3D G3DSA:3.30.70.260 5 87 1.3E-30 T 29-03-2018 MC49_RS10090 2f901b9ab8e258c2b5e413057724063f 87 Hamap MF_00659 UPF0250 protein YbeD [ybeD]. 1 87 26.46 T 29-03-2018 IPR007454 Uncharacterised protein family UPF0250 MC49_RS10090 2f901b9ab8e258c2b5e413057724063f 87 Pfam PF04359 Protein of unknown function (DUF493) 7 87 4.2E-30 T 29-03-2018 IPR007454 Uncharacterised protein family UPF0250 MC49_RS14975 0813aa89329ab97a88deb5881e9efb24 417 ProSitePatterns PS00216 Sugar transport proteins signature 1. 91 107 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MC49_RS14975 0813aa89329ab97a88deb5881e9efb24 417 Gene3D G3DSA:1.20.1250.20 31 224 2.8E-35 T 29-03-2018 MC49_RS14975 0813aa89329ab97a88deb5881e9efb24 417 SUPERFAMILY SSF103473 23 413 1.96E-64 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS14975 0813aa89329ab97a88deb5881e9efb24 417 Gene3D G3DSA:1.20.1250.20 225 417 1.2E-13 T 29-03-2018 MC49_RS14975 0813aa89329ab97a88deb5881e9efb24 417 Pfam PF07690 Major Facilitator Superfamily 42 344 2.7E-33 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS12370 bdb2d362f165df744666303213e3f2b0 100 Gene3D G3DSA:1.10.10.60 1 49 3.1E-6 T 29-03-2018 MC49_RS12370 bdb2d362f165df744666303213e3f2b0 100 SMART SM00530 32 87 2.0E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS12370 bdb2d362f165df744666303213e3f2b0 100 Gene3D G3DSA:3.30.1190.10 50 98 1.6E-9 T 29-03-2018 MC49_RS12370 bdb2d362f165df744666303213e3f2b0 100 Pfam PF13744 Helix-turn-helix domain 17 89 3.5E-11 T 29-03-2018 MC49_RS12370 bdb2d362f165df744666303213e3f2b0 100 SUPERFAMILY SSF47413 24 96 4.02E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS18120 a70a3500140b9614487f10457585ff6d 235 SUPERFAMILY SSF53167 4 233 1.15E-82 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MC49_RS18120 a70a3500140b9614487f10457585ff6d 235 TIGRFAM TIGR00107 deoD: purine nucleoside phosphorylase 5 233 8.4E-100 T 29-03-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 MC49_RS18120 a70a3500140b9614487f10457585ff6d 235 Hamap MF_01627 Purine nucleoside phosphorylase DeoD-type [deoD]. 1 234 45.936 T 29-03-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 MC49_RS18120 a70a3500140b9614487f10457585ff6d 235 Gene3D G3DSA:3.40.50.1580 8 235 2.2E-52 T 29-03-2018 MC49_RS18120 a70a3500140b9614487f10457585ff6d 235 Pfam PF01048 Phosphorylase superfamily 15 227 9.9E-40 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MC49_RS09535 d3ec3241b33e3b15cff3552dce5389ca 232 Hamap MF_01235 Putative N-acetylmannosamine-6-phosphate 2-epimerase [nanE]. 11 225 35.874 T 29-03-2018 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9 MC49_RS09535 d3ec3241b33e3b15cff3552dce5389ca 232 SUPERFAMILY SSF51366 13 224 3.53E-50 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MC49_RS09535 d3ec3241b33e3b15cff3552dce5389ca 232 Pfam PF04131 Putative N-acetylmannosamine-6-phosphate epimerase 35 225 8.4E-83 T 29-03-2018 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9 MC49_RS09535 d3ec3241b33e3b15cff3552dce5389ca 232 Gene3D G3DSA:3.20.20.70 1 229 7.3E-35 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS13830 f3587eed7a0194417195a9a0e87d4c05 154 Gene3D G3DSA:1.10.10.10 6 57 2.6E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS13830 f3587eed7a0194417195a9a0e87d4c05 154 SMART SM00344 5 114 7.9E-39 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MC49_RS13830 f3587eed7a0194417195a9a0e87d4c05 154 Gene3D G3DSA:3.30.70.920 58 151 3.6E-24 T 29-03-2018 MC49_RS13830 f3587eed7a0194417195a9a0e87d4c05 154 SUPERFAMILY SSF54909 69 153 1.61E-18 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel MC49_RS13830 f3587eed7a0194417195a9a0e87d4c05 154 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 52 7.4E-20 T 29-03-2018 MC49_RS13830 f3587eed7a0194417195a9a0e87d4c05 154 SUPERFAMILY SSF46785 4 64 4.23E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS13830 f3587eed7a0194417195a9a0e87d4c05 154 Pfam PF01037 Lrp/AsnC ligand binding domain 78 145 7.0E-19 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MC49_RS13830 f3587eed7a0194417195a9a0e87d4c05 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 1.5E-19 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MC49_RS13830 f3587eed7a0194417195a9a0e87d4c05 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 1.5E-19 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MC49_RS13830 f3587eed7a0194417195a9a0e87d4c05 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 1.5E-19 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MC49_RS04555 bec70e4c26d63d69b30f483795038307 394 TIGRFAM TIGR00695 uxuA: mannonate dehydratase 1 393 5.2E-210 T 29-03-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 MC49_RS04555 bec70e4c26d63d69b30f483795038307 394 Gene3D G3DSA:3.20.20.150 1 392 2.2E-111 T 29-03-2018 MC49_RS04555 bec70e4c26d63d69b30f483795038307 394 Hamap MF_00106 Mannonate dehydratase [uxuA]. 1 394 213.546 T 29-03-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 MC49_RS04555 bec70e4c26d63d69b30f483795038307 394 Pfam PF03786 D-mannonate dehydratase (UxuA) 1 387 1.8E-156 T 29-03-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 MC49_RS04555 bec70e4c26d63d69b30f483795038307 394 PIRSF PIRSF016049 1 392 3.1E-180 T 29-03-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 MC49_RS04555 bec70e4c26d63d69b30f483795038307 394 SUPERFAMILY SSF51658 1 133 9.4E-79 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MC49_RS04555 bec70e4c26d63d69b30f483795038307 394 SUPERFAMILY SSF51658 163 383 9.4E-79 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MC49_RS09890 5445ef5454cf1c70271b66ab3533b688 117 Pfam PF01245 Ribosomal protein L19 3 113 1.4E-50 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS09890 5445ef5454cf1c70271b66ab3533b688 117 PIRSF PIRSF002191 1 117 1.4E-51 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS09890 5445ef5454cf1c70271b66ab3533b688 117 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 3 113 6.2E-54 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS09890 5445ef5454cf1c70271b66ab3533b688 117 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 29-03-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS09890 5445ef5454cf1c70271b66ab3533b688 117 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 114 31.074 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS09890 5445ef5454cf1c70271b66ab3533b688 117 SUPERFAMILY SSF50104 2 115 9.33E-49 T 29-03-2018 IPR008991 Translation protein SH3-like domain MC49_RS09890 5445ef5454cf1c70271b66ab3533b688 117 PRINTS PR00061 Ribosomal protein L19 signature 88 113 9.8E-43 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS09890 5445ef5454cf1c70271b66ab3533b688 117 PRINTS PR00061 Ribosomal protein L19 signature 34 63 9.8E-43 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS09890 5445ef5454cf1c70271b66ab3533b688 117 PRINTS PR00061 Ribosomal protein L19 signature 4 33 9.8E-43 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS01205 b2906925208d38d0e92bb13ad34760ed 104 Pfam PF05284 Protein of unknown function (DUF736) 3 98 3.0E-35 T 29-03-2018 IPR007948 Protein of unknown function DUF736 MC49_RS15345 4e82b200402479c3b378c5c66412f2a6 136 PIRSF PIRSF002096 1 135 3.5E-52 T 29-03-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 MC49_RS15345 4e82b200402479c3b378c5c66412f2a6 136 Pfam PF00816 H-NS histone family 39 127 6.6E-20 T 29-03-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 MC49_RS15345 4e82b200402479c3b378c5c66412f2a6 136 Gene3D G3DSA:4.10.430.10 93 135 7.6E-19 T 29-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 MC49_RS15345 4e82b200402479c3b378c5c66412f2a6 136 SMART SM00528 87 135 5.8E-26 T 29-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 MC49_RS15345 4e82b200402479c3b378c5c66412f2a6 136 Gene3D G3DSA:1.10.287.1050 1 57 4.5E-22 T 29-03-2018 IPR027454 Histone-like protein H-NS family, oligomerisation domain GO:0046983 MC49_RS15345 4e82b200402479c3b378c5c66412f2a6 136 SUPERFAMILY SSF81273 93 135 1.22E-12 T 29-03-2018 MC49_RS15345 4e82b200402479c3b378c5c66412f2a6 136 SUPERFAMILY SSF81273 2 58 1.61E-15 T 29-03-2018 MC49_RS13810 08ab87d61af3ebe88bb20f1785773734 473 SUPERFAMILY SSF46785 1 70 4.76E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS13810 08ab87d61af3ebe88bb20f1785773734 473 SMART SM00345 7 66 1.4E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MC49_RS13810 08ab87d61af3ebe88bb20f1785773734 473 Gene3D G3DSA:3.40.640.10 120 369 7.6E-47 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS13810 08ab87d61af3ebe88bb20f1785773734 473 Pfam PF00155 Aminotransferase class I and II 146 459 1.3E-31 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MC49_RS13810 08ab87d61af3ebe88bb20f1785773734 473 SUPERFAMILY SSF53383 96 465 9.55E-94 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS13810 08ab87d61af3ebe88bb20f1785773734 473 Gene3D G3DSA:1.10.10.10 1 73 1.7E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS13810 08ab87d61af3ebe88bb20f1785773734 473 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 1.5E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MC49_RS13810 08ab87d61af3ebe88bb20f1785773734 473 Gene3D G3DSA:3.90.1150.10 370 467 2.3E-26 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS01885 50288387ebfecbb2207b6bd62ce77978 801 SUPERFAMILY SSF55008 106 167 8.12E-13 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MC49_RS01885 50288387ebfecbb2207b6bd62ce77978 801 Gene3D G3DSA:3.40.50.1000 622 760 3.6E-37 T 29-03-2018 IPR023214 HAD-like domain MC49_RS01885 50288387ebfecbb2207b6bd62ce77978 801 SUPERFAMILY SSF81665 742 789 3.53E-17 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MC49_RS01885 50288387ebfecbb2207b6bd62ce77978 801 SUPERFAMILY SSF81665 397 491 3.53E-17 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MC49_RS01885 50288387ebfecbb2207b6bd62ce77978 801 SUPERFAMILY SSF81665 249 300 3.53E-17 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MC49_RS01885 50288387ebfecbb2207b6bd62ce77978 801 Gene3D G3DSA:1.20.1110.10 247 514 1.8E-28 T 29-03-2018 MC49_RS01885 50288387ebfecbb2207b6bd62ce77978 801 Gene3D G3DSA:3.30.70.100 104 169 1.6E-13 T 29-03-2018 MC49_RS01885 50288387ebfecbb2207b6bd62ce77978 801 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 246 557 3.0E-96 T 29-03-2018 MC49_RS01885 50288387ebfecbb2207b6bd62ce77978 801 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 693 712 1.8E-29 T 29-03-2018 MC49_RS01885 50288387ebfecbb2207b6bd62ce77978 801 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 346 360 1.8E-29 T 29-03-2018 MC49_RS01885 50288387ebfecbb2207b6bd62ce77978 801 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 497 511 1.8E-29 T 29-03-2018 MC49_RS01885 50288387ebfecbb2207b6bd62ce77978 801 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 642 652 1.8E-29 T 29-03-2018 MC49_RS01885 50288387ebfecbb2207b6bd62ce77978 801 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 716 728 1.8E-29 T 29-03-2018 MC49_RS01885 50288387ebfecbb2207b6bd62ce77978 801 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 620 631 1.8E-29 T 29-03-2018 MC49_RS01885 50288387ebfecbb2207b6bd62ce77978 801 Pfam PF00702 haloacid dehalogenase-like hydrolase 493 706 1.1E-34 T 29-03-2018 MC49_RS01885 50288387ebfecbb2207b6bd62ce77978 801 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 499 505 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MC49_RS01885 50288387ebfecbb2207b6bd62ce77978 801 SUPERFAMILY SSF81653 299 396 8.63E-21 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 MC49_RS01885 50288387ebfecbb2207b6bd62ce77978 801 Gene3D G3DSA:3.40.1110.10 515 621 3.5E-26 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MC49_RS01885 50288387ebfecbb2207b6bd62ce77978 801 SUPERFAMILY SSF56784 495 515 1.3E-50 T 29-03-2018 IPR023214 HAD-like domain MC49_RS01885 50288387ebfecbb2207b6bd62ce77978 801 SUPERFAMILY SSF56784 610 792 1.3E-50 T 29-03-2018 IPR023214 HAD-like domain MC49_RS01885 50288387ebfecbb2207b6bd62ce77978 801 SUPERFAMILY SSF56784 554 579 1.3E-50 T 29-03-2018 IPR023214 HAD-like domain MC49_RS01885 50288387ebfecbb2207b6bd62ce77978 801 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 246 795 1.1E-173 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MC49_RS01885 50288387ebfecbb2207b6bd62ce77978 801 Pfam PF00122 E1-E2 ATPase 297 476 5.7E-47 T 29-03-2018 MC49_RS01885 50288387ebfecbb2207b6bd62ce77978 801 ProSitePatterns PS01047 Heavy-metal-associated domain. 112 141 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 MC49_RS01885 50288387ebfecbb2207b6bd62ce77978 801 Pfam PF00403 Heavy-metal-associated domain 111 167 2.0E-9 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MC49_RS01885 50288387ebfecbb2207b6bd62ce77978 801 ProSitePatterns PS01229 Hypothetical cof family signature 2. 693 715 - T 29-03-2018 MC49_RS01885 50288387ebfecbb2207b6bd62ce77978 801 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 269 771 1.1E-79 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MC49_RS01885 50288387ebfecbb2207b6bd62ce77978 801 PRINTS PR00941 Cadmium-transporting ATPase signature 110 119 1.9E-7 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MC49_RS01885 50288387ebfecbb2207b6bd62ce77978 801 PRINTS PR00941 Cadmium-transporting ATPase signature 301 317 1.9E-7 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MC49_RS01885 50288387ebfecbb2207b6bd62ce77978 801 PRINTS PR00941 Cadmium-transporting ATPase signature 281 301 1.9E-7 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MC49_RS01885 50288387ebfecbb2207b6bd62ce77978 801 PRINTS PR00941 Cadmium-transporting ATPase signature 362 378 1.9E-7 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MC49_RS01885 50288387ebfecbb2207b6bd62ce77978 801 PRINTS PR00941 Cadmium-transporting ATPase signature 121 142 1.9E-7 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MC49_RS01325 cea8194cd66140f70228ea22082879fb 377 Pfam PF14720 NiFe/NiFeSe hydrogenase small subunit C-terminal 228 307 1.5E-25 T 29-03-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal MC49_RS01325 cea8194cd66140f70228ea22082879fb 377 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 17 38 2.7E-5 T 29-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal MC49_RS01325 cea8194cd66140f70228ea22082879fb 377 PIRSF PIRSF000310 8 371 4.6E-131 T 29-03-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 MC49_RS01325 cea8194cd66140f70228ea22082879fb 377 Gene3D G3DSA:3.40.50.700 46 235 4.8E-53 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS01325 cea8194cd66140f70228ea22082879fb 377 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 63 208 1.1E-33 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS01325 cea8194cd66140f70228ea22082879fb 377 SUPERFAMILY SSF56770 50 306 1.01E-82 T 29-03-2018 MC49_RS01325 cea8194cd66140f70228ea22082879fb 377 Gene3D G3DSA:4.10.480.10 236 313 5.5E-28 T 29-03-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal MC49_RS01325 cea8194cd66140f70228ea22082879fb 377 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 160 184 4.8E-68 T 29-03-2018 MC49_RS01325 cea8194cd66140f70228ea22082879fb 377 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 189 212 4.8E-68 T 29-03-2018 MC49_RS01325 cea8194cd66140f70228ea22082879fb 377 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 233 251 4.8E-68 T 29-03-2018 MC49_RS01325 cea8194cd66140f70228ea22082879fb 377 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 215 232 4.8E-68 T 29-03-2018 MC49_RS01325 cea8194cd66140f70228ea22082879fb 377 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 48 70 4.8E-68 T 29-03-2018 MC49_RS01325 cea8194cd66140f70228ea22082879fb 377 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 117 140 4.8E-68 T 29-03-2018 MC49_RS01325 cea8194cd66140f70228ea22082879fb 377 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 71 95 4.8E-68 T 29-03-2018 MC49_RS01325 cea8194cd66140f70228ea22082879fb 377 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 257 283 4.8E-68 T 29-03-2018 MC49_RS01325 cea8194cd66140f70228ea22082879fb 377 TIGRFAM TIGR00391 hydA: hydrogenase (NiFe) small subunit (hydA) 3 368 2.2E-179 T 29-03-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 MC49_RS00510 f3bac5a1a197b00a1a1d908d784a7393 150 Pfam PF01957 NfeD-like C-terminal, partner-binding 13 147 1.3E-25 T 29-03-2018 IPR002810 NfeD-like, C-terminal domain MC49_RS00510 f3bac5a1a197b00a1a1d908d784a7393 150 Gene3D G3DSA:2.40.50.140 78 150 3.8E-13 T 29-03-2018 MC49_RS00510 f3bac5a1a197b00a1a1d908d784a7393 150 SUPERFAMILY SSF141322 85 148 3.14E-6 T 29-03-2018 MC49_RS10695 dffbe9b0c0427f072d06148b90d60cfb 167 Pfam PF00210 Ferritin-like domain 30 166 1.2E-21 T 29-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 MC49_RS10695 dffbe9b0c0427f072d06148b90d60cfb 167 SUPERFAMILY SSF47240 12 167 1.59E-47 T 29-03-2018 IPR009078 Ferritin-like superfamily MC49_RS10695 dffbe9b0c0427f072d06148b90d60cfb 167 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 51 67 7.5E-12 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 MC49_RS10695 dffbe9b0c0427f072d06148b90d60cfb 167 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 144 162 7.5E-12 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 MC49_RS10695 dffbe9b0c0427f072d06148b90d60cfb 167 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 75 91 7.5E-12 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 MC49_RS10695 dffbe9b0c0427f072d06148b90d60cfb 167 ProSitePatterns PS00818 Dps protein family signature 1. 51 67 - T 29-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 MC49_RS10695 dffbe9b0c0427f072d06148b90d60cfb 167 PIRSF PIRSF005900 8 167 8.5E-42 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 MC49_RS10695 dffbe9b0c0427f072d06148b90d60cfb 167 Gene3D G3DSA:1.20.1260.10 2 167 1.2E-38 T 29-03-2018 IPR012347 Ferritin-related MC49_RS10685 ec1d738310be38c9cdaae5a6a59d7b45 702 Pfam PF06733 DEAD_2 197 263 1.6E-7 T 29-03-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 MC49_RS10685 ec1d738310be38c9cdaae5a6a59d7b45 702 Pfam PF13307 Helicase C-terminal domain 534 689 2.7E-23 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 MC49_RS10685 ec1d738310be38c9cdaae5a6a59d7b45 702 SMART SM00491 545 677 6.5E-25 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 MC49_RS10685 ec1d738310be38c9cdaae5a6a59d7b45 702 SUPERFAMILY SSF52540 211 265 4.23E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS10685 ec1d738310be38c9cdaae5a6a59d7b45 702 SUPERFAMILY SSF52540 647 671 4.23E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS10685 ec1d738310be38c9cdaae5a6a59d7b45 702 SUPERFAMILY SSF52540 14 120 4.23E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS10685 ec1d738310be38c9cdaae5a6a59d7b45 702 SMART SM00487 23 306 4.1E-5 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MC49_RS10685 ec1d738310be38c9cdaae5a6a59d7b45 702 Gene3D G3DSA:3.40.50.300 503 688 4.2E-6 T 29-03-2018 MC49_RS10685 ec1d738310be38c9cdaae5a6a59d7b45 702 SMART SM00488 25 303 0.0025 T 29-03-2018 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 MC49_RS10685 ec1d738310be38c9cdaae5a6a59d7b45 702 Gene3D G3DSA:3.40.50.300 24 485 1.9E-24 T 29-03-2018 MC49_RS08870 ccf02a2c3519b917d0e62937eb594696 435 Pfam PF03313 Serine dehydratase alpha chain 195 425 9.7E-47 T 29-03-2018 IPR005130 Serine dehydratase-like, alpha subunit MC49_RS08870 ccf02a2c3519b917d0e62937eb594696 435 Hamap MF_01845 UPF0597 protein YhaM [yhaM]. 9 430 33.756 T 29-03-2018 IPR021144 Uncharacterised protein family UPF0597 MC49_RS08870 ccf02a2c3519b917d0e62937eb594696 435 Gene3D G3DSA:1.10.4100.10 264 396 2.7E-9 T 29-03-2018 MC49_RS08870 ccf02a2c3519b917d0e62937eb594696 435 PIRSF PIRSF006054 6 432 1.6E-158 T 29-03-2018 IPR021144 Uncharacterised protein family UPF0597 MC49_RS07750 e109e3dab61337e68dfbc70a28de5caf 753 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 646 697 4.7E-6 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MC49_RS07750 e109e3dab61337e68dfbc70a28de5caf 753 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 599 636 0.002 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MC49_RS07750 e109e3dab61337e68dfbc70a28de5caf 753 Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. 5 744 33.939 T 29-03-2018 IPR005742 DNA topoisomerase IV, subunit A, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MC49_RS07750 e109e3dab61337e68dfbc70a28de5caf 753 Gene3D G3DSA:2.120.10.90 496 749 2.3E-40 T 29-03-2018 MC49_RS07750 e109e3dab61337e68dfbc70a28de5caf 753 TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 9 740 0.0 T 29-03-2018 MC49_RS07750 e109e3dab61337e68dfbc70a28de5caf 753 Gene3D G3DSA:1.10.268.10 345 484 9.0E-46 T 29-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MC49_RS07750 e109e3dab61337e68dfbc70a28de5caf 753 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 33 469 3.8E-130 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MC49_RS07750 e109e3dab61337e68dfbc70a28de5caf 753 Gene3D G3DSA:3.90.199.10 35 284 1.6E-96 T 29-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 MC49_RS07750 e109e3dab61337e68dfbc70a28de5caf 753 SMART SM00434 12 462 4.7E-224 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MC49_RS07750 e109e3dab61337e68dfbc70a28de5caf 753 SUPERFAMILY SSF101904 499 742 2.22E-51 T 29-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal MC49_RS07750 e109e3dab61337e68dfbc70a28de5caf 753 SUPERFAMILY SSF56719 32 483 1.96E-152 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MC49_RS10065 0363a5b30ea6750a16ffedd8320cadee 155 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 11 153 35.93 T 29-03-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 MC49_RS10065 0363a5b30ea6750a16ffedd8320cadee 155 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 74 154 3.1E-28 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MC49_RS10065 0363a5b30ea6750a16ffedd8320cadee 155 SUPERFAMILY SSF53155 2 77 3.14E-14 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MC49_RS10065 0363a5b30ea6750a16ffedd8320cadee 155 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 123 129 - T 29-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MC49_RS10065 0363a5b30ea6750a16ffedd8320cadee 155 SUPERFAMILY SSF46767 72 154 1.09E-28 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MC49_RS10065 0363a5b30ea6750a16ffedd8320cadee 155 Gene3D G3DSA:1.10.10.10 69 155 1.6E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS10065 0363a5b30ea6750a16ffedd8320cadee 155 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 73 152 1.0E-30 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MC49_RS10065 0363a5b30ea6750a16ffedd8320cadee 155 Gene3D G3DSA:3.30.160.70 1 68 7.2E-15 T 29-03-2018 MC49_RS18580 b73ae7d46413438c7423e1bd8cd5c76c 399 Pfam PF00482 Type II secretion system (T2SS), protein F 64 187 4.5E-30 T 29-03-2018 IPR018076 Type II secretion system F domain MC49_RS18580 b73ae7d46413438c7423e1bd8cd5c76c 399 Pfam PF00482 Type II secretion system (T2SS), protein F 270 390 1.2E-18 T 29-03-2018 IPR018076 Type II secretion system F domain MC49_RS18580 b73ae7d46413438c7423e1bd8cd5c76c 399 PRINTS PR00812 Bacterial general secretion pathway protein F signature 159 187 2.6E-13 T 29-03-2018 IPR003004 GspF/PilC family MC49_RS18580 b73ae7d46413438c7423e1bd8cd5c76c 399 PRINTS PR00812 Bacterial general secretion pathway protein F signature 363 377 2.6E-13 T 29-03-2018 IPR003004 GspF/PilC family MC49_RS18580 b73ae7d46413438c7423e1bd8cd5c76c 399 PRINTS PR00812 Bacterial general secretion pathway protein F signature 60 72 2.6E-13 T 29-03-2018 IPR003004 GspF/PilC family MC49_RS18580 b73ae7d46413438c7423e1bd8cd5c76c 399 PRINTS PR00812 Bacterial general secretion pathway protein F signature 379 398 2.6E-13 T 29-03-2018 IPR003004 GspF/PilC family MC49_RS00790 d6745dcf09cbc385bb808a1adb6b14c9 204 Pfam PF00510 Cytochrome c oxidase subunit III 16 202 1.2E-14 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MC49_RS00790 d6745dcf09cbc385bb808a1adb6b14c9 204 Gene3D G3DSA:1.20.120.80 19 204 1.7E-52 T 29-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MC49_RS00790 d6745dcf09cbc385bb808a1adb6b14c9 204 SUPERFAMILY SSF81452 9 202 3.01E-58 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MC49_RS00790 d6745dcf09cbc385bb808a1adb6b14c9 204 TIGRFAM TIGR02842 CyoC: cytochrome o ubiquinol oxidase, subunit III 25 204 3.6E-86 T 29-03-2018 IPR014206 Cytochrome o ubiquinol oxidase, subunit III GO:0005886|GO:0008827|GO:0019646 MC49_RS04255 758d46e5d2d8a785564f0490b8b9ff43 629 Gene3D G3DSA:2.170.130.10 21 157 2.9E-34 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MC49_RS04255 758d46e5d2d8a785564f0490b8b9ff43 629 TIGRFAM TIGR01779 TonB-B12: TonB-dependent vitamin B12 receptor 9 629 1.7E-205 T 29-03-2018 IPR010101 TonB-dependent vitamin B12 transporter BtuB GO:0004872|GO:0015235|GO:0015889|GO:0016020 MC49_RS04255 758d46e5d2d8a785564f0490b8b9ff43 629 SUPERFAMILY SSF56935 31 629 6.92E-119 T 29-03-2018 MC49_RS04255 758d46e5d2d8a785564f0490b8b9ff43 629 Gene3D G3DSA:2.40.170.20 158 629 1.2E-69 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MC49_RS04255 758d46e5d2d8a785564f0490b8b9ff43 629 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 612 629 - T 29-03-2018 IPR010917 TonB-dependent receptor, conserved site MC49_RS04255 758d46e5d2d8a785564f0490b8b9ff43 629 Hamap MF_01531 Vitamin B12 transporter BtuB [btuB]. 3 629 34.036 T 29-03-2018 IPR010101 TonB-dependent vitamin B12 transporter BtuB GO:0004872|GO:0015235|GO:0015889|GO:0016020 MC49_RS04255 758d46e5d2d8a785564f0490b8b9ff43 629 Pfam PF07715 TonB-dependent Receptor Plug Domain 45 151 6.0E-29 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MC49_RS04255 758d46e5d2d8a785564f0490b8b9ff43 629 Pfam PF00593 TonB dependent receptor 207 628 4.1E-46 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MC49_RS17065 9adfa05409015387ed7ff7c1f0e2986c 332 SUPERFAMILY SSF52540 1 206 6.88E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS17065 9adfa05409015387ed7ff7c1f0e2986c 332 Gene3D G3DSA:3.40.50.300 8 164 4.7E-23 T 29-03-2018 MC49_RS17065 9adfa05409015387ed7ff7c1f0e2986c 332 Gene3D G3DSA:1.20.272.10 209 330 1.1E-19 T 29-03-2018 MC49_RS17065 9adfa05409015387ed7ff7c1f0e2986c 332 Pfam PF09115 DNA polymerase III, delta subunit, C terminal 210 322 1.6E-34 T 29-03-2018 IPR015199 DNA polymerase III, delta subunit, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS17065 9adfa05409015387ed7ff7c1f0e2986c 332 Gene3D G3DSA:1.10.8.10 170 206 1.6E-12 T 29-03-2018 MC49_RS17065 9adfa05409015387ed7ff7c1f0e2986c 332 SUPERFAMILY SSF48019 211 327 1.07E-30 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 MC49_RS17065 9adfa05409015387ed7ff7c1f0e2986c 332 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 12 201 1.6E-57 T 29-03-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS17065 9adfa05409015387ed7ff7c1f0e2986c 332 Pfam PF13177 DNA polymerase III, delta subunit 10 166 6.3E-43 T 29-03-2018 MC49_RS15095 a6d878c87d18931647f2e2b625025a0b 890 ProSitePatterns PS00450 Aconitase family signature 1. 426 442 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MC49_RS15095 a6d878c87d18931647f2e2b625025a0b 890 Gene3D G3DSA:3.30.499.10 25 239 1.4E-74 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS15095 a6d878c87d18931647f2e2b625025a0b 890 Gene3D G3DSA:3.30.499.10 372 575 9.7E-62 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS15095 a6d878c87d18931647f2e2b625025a0b 890 Gene3D G3DSA:3.40.1060.10 240 371 1.4E-44 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS15095 a6d878c87d18931647f2e2b625025a0b 890 Pfam PF00330 Aconitase family (aconitate hydratase) 69 561 2.2E-178 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS15095 a6d878c87d18931647f2e2b625025a0b 890 Gene3D G3DSA:3.20.19.10 651 890 4.0E-93 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel MC49_RS15095 a6d878c87d18931647f2e2b625025a0b 890 SUPERFAMILY SSF52016 628 889 4.12E-90 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel MC49_RS15095 a6d878c87d18931647f2e2b625025a0b 890 Pfam PF00694 Aconitase C-terminal domain 690 817 6.4E-48 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS15095 a6d878c87d18931647f2e2b625025a0b 890 SUPERFAMILY SSF53732 13 625 6.8E-219 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS15095 a6d878c87d18931647f2e2b625025a0b 890 ProSitePatterns PS01244 Aconitase family signature 2. 492 505 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MC49_RS15095 a6d878c87d18931647f2e2b625025a0b 890 PRINTS PR00415 Aconitase family signature 217 232 6.4E-41 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS15095 a6d878c87d18931647f2e2b625025a0b 890 PRINTS PR00415 Aconitase family signature 146 159 6.4E-41 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS15095 a6d878c87d18931647f2e2b625025a0b 890 PRINTS PR00415 Aconitase family signature 372 386 6.4E-41 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS15095 a6d878c87d18931647f2e2b625025a0b 890 PRINTS PR00415 Aconitase family signature 492 505 6.4E-41 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS15095 a6d878c87d18931647f2e2b625025a0b 890 PRINTS PR00415 Aconitase family signature 170 178 6.4E-41 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS15095 a6d878c87d18931647f2e2b625025a0b 890 PRINTS PR00415 Aconitase family signature 430 441 6.4E-41 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS15095 a6d878c87d18931647f2e2b625025a0b 890 PRINTS PR00415 Aconitase family signature 203 216 6.4E-41 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS15095 a6d878c87d18931647f2e2b625025a0b 890 PRINTS PR00415 Aconitase family signature 279 292 6.4E-41 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS15095 a6d878c87d18931647f2e2b625025a0b 890 PRINTS PR00415 Aconitase family signature 293 306 6.4E-41 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS15095 a6d878c87d18931647f2e2b625025a0b 890 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 18 889 0.0 T 29-03-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 MC49_RS03570 992a0fa8af82d8c8ce1d6d7778640944 142 Gene3D G3DSA:1.10.10.10 1 137 5.6E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS03570 992a0fa8af82d8c8ce1d6d7778640944 142 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 29-03-2018 IPR030489 Transcription regulator Rrf2-type, conserved site MC49_RS03570 992a0fa8af82d8c8ce1d6d7778640944 142 Pfam PF02082 Transcriptional regulator 2 83 6.4E-23 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type MC49_RS03570 992a0fa8af82d8c8ce1d6d7778640944 142 Hamap MF_01177 HTH-type transcriptional repressor NsrR [nsrR]. 1 141 44.784 T 29-03-2018 IPR023761 Transcriptional repressor HTH, NsrR GO:0045892 MC49_RS03570 992a0fa8af82d8c8ce1d6d7778640944 142 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 2 128 5.2E-35 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type MC49_RS03570 992a0fa8af82d8c8ce1d6d7778640944 142 SUPERFAMILY SSF46785 2 131 1.75E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS13590 6e54ced6947bafa43f50b24b06b3e2a2 297 SUPERFAMILY SSF51695 10 279 4.34E-47 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 MC49_RS13590 6e54ced6947bafa43f50b24b06b3e2a2 297 Gene3D G3DSA:3.20.20.190 5 280 4.5E-46 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 MC49_RS13590 6e54ced6947bafa43f50b24b06b3e2a2 297 Pfam PF00388 Phosphatidylinositol-specific phospholipase C, X domain 49 161 2.3E-10 T 29-03-2018 IPR000909 Phosphatidylinositol-specific phospholipase C, X domain MC49_RS13590 6e54ced6947bafa43f50b24b06b3e2a2 297 SMART SM00148 16 161 2.4E-9 T 29-03-2018 IPR000909 Phosphatidylinositol-specific phospholipase C, X domain MC49_RS01940 8b4447538c6c16e7208645d999c913c8 130 Hamap MF_00708 Fumarate reductase subunit C [frdC]. 2 128 28.07 T 29-03-2018 IPR003510 Fumarate reductase, subunit C GO:0016020 MC49_RS01940 8b4447538c6c16e7208645d999c913c8 130 PIRSF PIRSF000180 2 130 7.4E-56 T 29-03-2018 IPR003510 Fumarate reductase, subunit C GO:0016020 MC49_RS01940 8b4447538c6c16e7208645d999c913c8 130 SUPERFAMILY SSF81343 2 129 5.67E-54 T 29-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MC49_RS01940 8b4447538c6c16e7208645d999c913c8 130 Gene3D G3DSA:1.20.1300.10 3 128 1.9E-52 T 29-03-2018 MC49_RS01940 8b4447538c6c16e7208645d999c913c8 130 ProDom PD015900 FUMARATE MEMBRANE REDUCTASE C SUBUNIT TRANSMEMBRANE INNER HYDROPHOBIC REDUCTASE POLYPEPTIDE 8 129 3.0E-46 T 29-03-2018 IPR003510 Fumarate reductase, subunit C GO:0016020 MC49_RS01940 8b4447538c6c16e7208645d999c913c8 130 Pfam PF02300 Fumarate reductase subunit C 3 128 8.1E-53 T 29-03-2018 IPR003510 Fumarate reductase, subunit C GO:0016020 MC49_RS12860 76704346c4f0f639d7582886478ac09a 383 SUPERFAMILY SSF56349 56 358 7.65E-52 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MC49_RS12860 76704346c4f0f639d7582886478ac09a 383 Gene3D G3DSA:1.10.150.130 52 181 4.0E-11 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal MC49_RS12860 76704346c4f0f639d7582886478ac09a 383 Gene3D G3DSA:1.10.443.10 182 363 5.4E-40 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MC49_RS12860 76704346c4f0f639d7582886478ac09a 383 Pfam PF00589 Phage integrase family 181 349 1.3E-42 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MC49_RS14090 7792b35be947667aaeb7b74aeddad662 458 Pfam PF01476 LysM domain 117 158 1.9E-5 T 29-03-2018 IPR018392 LysM domain MC49_RS14090 7792b35be947667aaeb7b74aeddad662 458 Pfam PF08525 Opacity-associated protein A N-terminal motif 11 39 1.2E-5 T 29-03-2018 IPR013731 Opacity-associated protein A, N-terminal MC49_RS14090 7792b35be947667aaeb7b74aeddad662 458 SUPERFAMILY SSF51261 182 426 2.35E-68 T 29-03-2018 IPR011055 Duplicated hybrid motif MC49_RS14090 7792b35be947667aaeb7b74aeddad662 458 Pfam PF01551 Peptidase family M23 331 425 8.6E-34 T 29-03-2018 IPR016047 Peptidase M23 MC49_RS14090 7792b35be947667aaeb7b74aeddad662 458 SMART SM00257 116 161 0.0055 T 29-03-2018 IPR018392 LysM domain MC49_RS14090 7792b35be947667aaeb7b74aeddad662 458 Gene3D G3DSA:3.10.350.10 101 203 2.5E-6 T 29-03-2018 MC49_RS14090 7792b35be947667aaeb7b74aeddad662 458 Gene3D G3DSA:2.70.70.10 214 428 2.2E-45 T 29-03-2018 MC49_RS16850 999c8b1f98fa6a0348f782e838c80496 61 Gene3D G3DSA:3.30.160.160 3 50 3.0E-18 T 29-03-2018 IPR010879 Domain of unknown function DUF1508 MC49_RS16850 999c8b1f98fa6a0348f782e838c80496 61 SUPERFAMILY SSF160113 11 60 3.01E-18 T 29-03-2018 IPR010879 Domain of unknown function DUF1508 MC49_RS16850 999c8b1f98fa6a0348f782e838c80496 61 Pfam PF07411 Domain of unknown function (DUF1508) 17 59 6.9E-22 T 29-03-2018 IPR010879 Domain of unknown function DUF1508 MC49_RS16670 2a69c4d3350473fab9a9f0fdb3d3798d 404 SUPERFAMILY SSF53901 213 402 2.51E-61 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MC49_RS16670 2a69c4d3350473fab9a9f0fdb3d3798d 404 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 252 359 9.2E-30 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MC49_RS16670 2a69c4d3350473fab9a9f0fdb3d3798d 404 Gene3D G3DSA:3.40.47.10 4 257 2.2E-57 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MC49_RS16670 2a69c4d3350473fab9a9f0fdb3d3798d 404 SUPERFAMILY SSF53901 1 251 8.56E-65 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MC49_RS16670 2a69c4d3350473fab9a9f0fdb3d3798d 404 SMART SM00825 Beta-ketoacyl synthase 4 404 7.8E-15 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MC49_RS16670 2a69c4d3350473fab9a9f0fdb3d3798d 404 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 152 168 - T 29-03-2018 IPR018201 Beta-ketoacyl synthase, active site MC49_RS16670 2a69c4d3350473fab9a9f0fdb3d3798d 404 Gene3D G3DSA:3.40.47.10 260 404 8.4E-41 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MC49_RS16670 2a69c4d3350473fab9a9f0fdb3d3798d 404 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2 244 3.9E-42 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MC49_RS03560 b901f3f77a356354b8d284ab05d49266 244 Gene3D G3DSA:3.40.1280.10 77 243 1.3E-52 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MC49_RS03560 b901f3f77a356354b8d284ab05d49266 244 SUPERFAMILY SSF75217 80 242 9.16E-51 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases MC49_RS03560 b901f3f77a356354b8d284ab05d49266 244 Pfam PF00588 SpoU rRNA Methylase family 96 236 1.4E-41 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MC49_RS03560 b901f3f77a356354b8d284ab05d49266 244 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 1 242 1.2E-88 T 29-03-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 MC49_RS03560 b901f3f77a356354b8d284ab05d49266 244 SMART SM00967 4 80 3.1E-19 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 MC49_RS03560 b901f3f77a356354b8d284ab05d49266 244 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 4 75 4.1E-19 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 MC49_RS03560 b901f3f77a356354b8d284ab05d49266 244 Gene3D G3DSA:3.30.1330.30 1 75 1.3E-16 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like MC49_RS03560 b901f3f77a356354b8d284ab05d49266 244 SUPERFAMILY SSF55315 2 75 4.12E-19 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like MC49_RS03560 b901f3f77a356354b8d284ab05d49266 244 Hamap MF_01887 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB [rlmB]. 2 243 44.028 T 29-03-2018 IPR024915 23S rRNA (guanosine-2-O-)-methyltransferase RlmB MC49_RS12325 0ddb6114711ae80ba3b0e8851521801e 410 Gene3D G3DSA:1.20.1250.20 4 203 2.3E-41 T 29-03-2018 MC49_RS12325 0ddb6114711ae80ba3b0e8851521801e 410 Gene3D G3DSA:1.20.1250.20 206 407 2.1E-31 T 29-03-2018 MC49_RS12325 0ddb6114711ae80ba3b0e8851521801e 410 SUPERFAMILY SSF103473 1 401 3.4E-78 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS12325 0ddb6114711ae80ba3b0e8851521801e 410 Pfam PF07690 Major Facilitator Superfamily 17 258 4.8E-39 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS12325 0ddb6114711ae80ba3b0e8851521801e 410 Hamap MF_01528 Multidrug resistance protein MdtG [mdtG]. 1 404 41.172 T 29-03-2018 IPR023692 Multidrug resistance protein MdtG GO:0005215|GO:0005886 MC49_RS12325 0ddb6114711ae80ba3b0e8851521801e 410 PRINTS PR01035 Tetracycline resistance protein signature 23 39 2.6E-11 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MC49_RS12325 0ddb6114711ae80ba3b0e8851521801e 410 PRINTS PR01035 Tetracycline resistance protein signature 85 109 2.6E-11 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MC49_RS12325 0ddb6114711ae80ba3b0e8851521801e 410 PRINTS PR01035 Tetracycline resistance protein signature 112 133 2.6E-11 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MC49_RS12325 0ddb6114711ae80ba3b0e8851521801e 410 PRINTS PR01035 Tetracycline resistance protein signature 142 164 2.6E-11 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MC49_RS12325 0ddb6114711ae80ba3b0e8851521801e 410 PRINTS PR01035 Tetracycline resistance protein signature 346 369 2.6E-11 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MC49_RS14310 79d3d38464c954c493849922c24f937c 507 SUPERFAMILY SSF55781 22 170 3.27E-18 T 29-03-2018 IPR029016 GAF domain-like MC49_RS14310 79d3d38464c954c493849922c24f937c 507 SUPERFAMILY SSF52540 189 423 4.11E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS14310 79d3d38464c954c493849922c24f937c 507 Pfam PF00158 Sigma-54 interaction domain 190 356 8.0E-65 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MC49_RS14310 79d3d38464c954c493849922c24f937c 507 Gene3D G3DSA:1.10.8.60 363 463 2.2E-21 T 29-03-2018 MC49_RS14310 79d3d38464c954c493849922c24f937c 507 Gene3D G3DSA:3.30.450.40 6 182 1.1E-17 T 29-03-2018 IPR029016 GAF domain-like MC49_RS14310 79d3d38464c954c493849922c24f937c 507 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 470 487 1.2E-5 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MC49_RS14310 79d3d38464c954c493849922c24f937c 507 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 487 507 1.2E-5 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MC49_RS14310 79d3d38464c954c493849922c24f937c 507 SMART SM00065 20 167 4.4E-18 T 29-03-2018 IPR003018 GAF domain GO:0005515 MC49_RS14310 79d3d38464c954c493849922c24f937c 507 Gene3D G3DSA:1.10.10.60 464 507 1.9E-9 T 29-03-2018 MC49_RS14310 79d3d38464c954c493849922c24f937c 507 Gene3D G3DSA:3.40.50.300 185 362 5.7E-26 T 29-03-2018 MC49_RS14310 79d3d38464c954c493849922c24f937c 507 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 276 291 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MC49_RS14310 79d3d38464c954c493849922c24f937c 507 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 403 412 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site MC49_RS14310 79d3d38464c954c493849922c24f937c 507 SMART SM00382 210 354 1.1E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS14310 79d3d38464c954c493849922c24f937c 507 SUPERFAMILY SSF46689 403 506 5.82E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS14310 79d3d38464c954c493849922c24f937c 507 Pfam PF01590 GAF domain 23 161 2.2E-10 T 29-03-2018 IPR003018 GAF domain GO:0005515 MC49_RS14310 79d3d38464c954c493849922c24f937c 507 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 214 227 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MC49_RS09715 44b14695ec0964f9b43369bda23254f4 264 PIRSF PIRSF009437 3 262 8.7E-91 T 29-03-2018 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0055114 MC49_RS09715 44b14695ec0964f9b43369bda23254f4 264 TIGRFAM TIGR01938 nqrC: NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit 9 254 2.8E-85 T 29-03-2018 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0055114 MC49_RS09715 44b14695ec0964f9b43369bda23254f4 264 SMART SM00900 150 247 1.3E-25 T 29-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 MC49_RS09715 44b14695ec0964f9b43369bda23254f4 264 Hamap MF_00427 Na(+)-translocating NADH-quinone reductase subunit C [nqrC]. 10 259 34.636 T 29-03-2018 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0055114 MC49_RS09715 44b14695ec0964f9b43369bda23254f4 264 Pfam PF04205 FMN-binding domain 150 244 2.4E-12 T 29-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 MC49_RS10140 4ef3401be9108d5f04ee9635759ab210 218 Gene3D G3DSA:3.40.50.620 3 218 1.7E-52 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS10140 4ef3401be9108d5f04ee9635759ab210 218 Pfam PF01467 Cytidylyltransferase-like 12 192 2.9E-32 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MC49_RS10140 4ef3401be9108d5f04ee9635759ab210 218 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 8 218 29.849 T 29-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 MC49_RS10140 4ef3401be9108d5f04ee9635759ab210 218 SUPERFAMILY SSF52374 9 218 1.21E-54 T 29-03-2018 MC49_RS10140 4ef3401be9108d5f04ee9635759ab210 218 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 11 73 3.0E-10 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MC49_RS10140 4ef3401be9108d5f04ee9635759ab210 218 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 12 217 2.6E-53 T 29-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 MC49_RS03590 2ef1f28ddf94e266846c9258166b7373 426 Gene3D G3DSA:3.40.50.300 165 229 8.4E-12 T 29-03-2018 MC49_RS03590 2ef1f28ddf94e266846c9258166b7373 426 Pfam PF13167 GTP-binding GTPase N-terminal 25 112 7.8E-30 T 29-03-2018 IPR025121 GTPase HflX, N-terminal MC49_RS03590 2ef1f28ddf94e266846c9258166b7373 426 PIRSF PIRSF006809 4 422 6.3E-146 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 MC49_RS03590 2ef1f28ddf94e266846c9258166b7373 426 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 200 220 2.6E-9 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MC49_RS03590 2ef1f28ddf94e266846c9258166b7373 426 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 267 285 2.6E-9 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MC49_RS03590 2ef1f28ddf94e266846c9258166b7373 426 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 221 239 2.6E-9 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MC49_RS03590 2ef1f28ddf94e266846c9258166b7373 426 Gene3D G3DSA:3.40.50.300 230 371 6.5E-18 T 29-03-2018 MC49_RS03590 2ef1f28ddf94e266846c9258166b7373 426 SUPERFAMILY SSF54980 366 421 5.47E-12 T 29-03-2018 IPR035647 EF-G domain III/V-like MC49_RS03590 2ef1f28ddf94e266846c9258166b7373 426 Hamap MF_00900 GTPase HflX [hflX]. 27 390 46.495 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 MC49_RS03590 2ef1f28ddf94e266846c9258166b7373 426 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 10 361 1.7E-153 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 MC49_RS03590 2ef1f28ddf94e266846c9258166b7373 426 Pfam PF01926 50S ribosome-binding GTPase 200 318 1.1E-21 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MC49_RS03590 2ef1f28ddf94e266846c9258166b7373 426 Pfam PF16360 GTP-binding GTPase Middle Region 114 192 2.7E-28 T 29-03-2018 IPR032305 GTP-binding protein, middle domain MC49_RS03590 2ef1f28ddf94e266846c9258166b7373 426 SUPERFAMILY SSF52540 197 373 3.67E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS01105 09f69f18c3f9aef2b63e0f461a41f992 474 Gene3D G3DSA:1.20.1600.10 24 469 2.0E-67 T 29-03-2018 MC49_RS01105 09f69f18c3f9aef2b63e0f461a41f992 474 Pfam PF02321 Outer membrane efflux protein 72 255 2.7E-16 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MC49_RS01105 09f69f18c3f9aef2b63e0f461a41f992 474 Pfam PF02321 Outer membrane efflux protein 284 455 2.8E-26 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MC49_RS01105 09f69f18c3f9aef2b63e0f461a41f992 474 SUPERFAMILY SSF56954 8 39 1.27E-78 T 29-03-2018 MC49_RS01105 09f69f18c3f9aef2b63e0f461a41f992 474 SUPERFAMILY SSF56954 62 464 1.27E-78 T 29-03-2018 MC49_RS01105 09f69f18c3f9aef2b63e0f461a41f992 474 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 18 463 1.6E-69 T 29-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 MC49_RS18835 fcbdea1e121446d5b9ed34df6d300343 337 Pfam PF02653 Branched-chain amino acid transport system / permease component 42 326 3.8E-50 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 MC49_RS18835 fcbdea1e121446d5b9ed34df6d300343 337 Gene3D G3DSA:1.10.3470.10 30 332 1.6E-32 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like MC49_RS09375 bf1bb41137a8ac86ae53b367c465b1a7 269 Pfam PF08282 haloacid dehalogenase-like hydrolase 4 258 2.9E-45 T 29-03-2018 IPR023214 HAD-like domain MC49_RS09375 bf1bb41137a8ac86ae53b367c465b1a7 269 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 231 4.7E-19 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 MC49_RS09375 bf1bb41137a8ac86ae53b367c465b1a7 269 SUPERFAMILY SSF56784 3 261 3.93E-48 T 29-03-2018 IPR023214 HAD-like domain MC49_RS09375 bf1bb41137a8ac86ae53b367c465b1a7 269 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 258 2.9E-41 T 29-03-2018 IPR000150 Cof family GO:0016787 MC49_RS09375 bf1bb41137a8ac86ae53b367c465b1a7 269 Gene3D G3DSA:3.40.50.1000 1 268 1.3E-28 T 29-03-2018 IPR023214 HAD-like domain MC49_RS06520 ebd53f7be7687b8416f7135b507f326c 260 Pfam PF00293 NUDIX domain 133 235 2.1E-14 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MC49_RS06520 ebd53f7be7687b8416f7135b507f326c 260 SUPERFAMILY SSF55811 2 96 5.27E-26 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MC49_RS06520 ebd53f7be7687b8416f7135b507f326c 260 ProSitePatterns PS00893 Nudix box signature. 160 181 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MC49_RS06520 ebd53f7be7687b8416f7135b507f326c 260 Gene3D G3DSA:3.90.79.10 126 258 2.0E-30 T 29-03-2018 MC49_RS06520 ebd53f7be7687b8416f7135b507f326c 260 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 93 124 4.2E-10 T 29-03-2018 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 MC49_RS06520 ebd53f7be7687b8416f7135b507f326c 260 Hamap MF_00297 NADH pyrophosphatase [nudC]. 1 258 41.841 T 29-03-2018 IPR022925 NADH pyrophosphatase NudC GO:0000210 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 MC49_RS06520 ebd53f7be7687b8416f7135b507f326c 260 SUPERFAMILY SSF55811 79 244 3.52E-36 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MC49_RS16810 f4756b0813a4d534ba29ced10dd4d460 235 SUPERFAMILY SSF47413 4 87 3.1E-20 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS16810 f4756b0813a4d534ba29ced10dd4d460 235 Pfam PF00717 Peptidase S24-like 148 220 5.0E-12 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MC49_RS16810 f4756b0813a4d534ba29ced10dd4d460 235 Gene3D G3DSA:1.10.260.40 1 85 5.6E-10 T 29-03-2018 MC49_RS16810 f4756b0813a4d534ba29ced10dd4d460 235 SMART SM00530 17 76 2.2E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS16810 f4756b0813a4d534ba29ced10dd4d460 235 Gene3D G3DSA:2.10.109.10 111 235 2.2E-20 T 29-03-2018 MC49_RS16810 f4756b0813a4d534ba29ced10dd4d460 235 Pfam PF01381 Helix-turn-helix 26 76 2.4E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS16810 f4756b0813a4d534ba29ced10dd4d460 235 SUPERFAMILY SSF51306 106 232 6.45E-26 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MC49_RS12140 4fa3225e0acdfefb7d7624757e69a1e4 66 PIRSF PIRSF039003 3 66 2.0E-31 T 29-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 MC49_RS12140 4fa3225e0acdfefb7d7624757e69a1e4 66 TIGRFAM TIGR03412 iscX_yfhJ: FeS assembly protein IscX 4 66 6.2E-32 T 29-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 MC49_RS12140 4fa3225e0acdfefb7d7624757e69a1e4 66 Pfam PF04384 Iron-sulphur cluster assembly 3 66 3.8E-31 T 29-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 MC49_RS12140 4fa3225e0acdfefb7d7624757e69a1e4 66 Gene3D G3DSA:1.10.10.600 2 64 1.4E-32 T 29-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 MC49_RS12140 4fa3225e0acdfefb7d7624757e69a1e4 66 SUPERFAMILY SSF140319 3 64 6.93E-26 T 29-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 MC49_RS08765 b7f9368127364c7102515db525783b87 310 Gene3D G3DSA:3.40.1160.10 1 309 1.1E-56 T 29-03-2018 MC49_RS08765 b7f9368127364c7102515db525783b87 310 SUPERFAMILY SSF53633 3 308 6.15E-80 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MC49_RS08765 b7f9368127364c7102515db525783b87 310 Pfam PF00696 Amino acid kinase family 3 290 2.3E-27 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MC49_RS08765 b7f9368127364c7102515db525783b87 310 TIGRFAM TIGR00746 arcC: carbamate kinase 3 308 7.4E-112 T 29-03-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 MC49_RS08765 b7f9368127364c7102515db525783b87 310 PIRSF PIRSF000723 1 310 1.5E-118 T 29-03-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 MC49_RS08765 b7f9368127364c7102515db525783b87 310 PRINTS PR01469 Bacterial carbamate kinase signature 39 58 1.3E-62 T 29-03-2018 MC49_RS08765 b7f9368127364c7102515db525783b87 310 PRINTS PR01469 Bacterial carbamate kinase signature 108 127 1.3E-62 T 29-03-2018 MC49_RS08765 b7f9368127364c7102515db525783b87 310 PRINTS PR01469 Bacterial carbamate kinase signature 156 175 1.3E-62 T 29-03-2018 MC49_RS08765 b7f9368127364c7102515db525783b87 310 PRINTS PR01469 Bacterial carbamate kinase signature 264 279 1.3E-62 T 29-03-2018 MC49_RS08765 b7f9368127364c7102515db525783b87 310 PRINTS PR01469 Bacterial carbamate kinase signature 73 91 1.3E-62 T 29-03-2018 MC49_RS08765 b7f9368127364c7102515db525783b87 310 PRINTS PR01469 Bacterial carbamate kinase signature 179 197 1.3E-62 T 29-03-2018 MC49_RS08765 b7f9368127364c7102515db525783b87 310 PRINTS PR01469 Bacterial carbamate kinase signature 209 224 1.3E-62 T 29-03-2018 MC49_RS18635 7e3dc5d449fa9611cf4df48ac3f9d461 267 Pfam PF03799 Cell division protein FtsQ 132 246 1.6E-26 T 29-03-2018 IPR005548 Cell division protein FtsQ/DivIB MC49_RS18635 7e3dc5d449fa9611cf4df48ac3f9d461 267 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 28 254 23.759 T 29-03-2018 IPR026579 Cell division protein FtsQ GO:0090529 MC49_RS18635 7e3dc5d449fa9611cf4df48ac3f9d461 267 Pfam PF08478 POTRA domain, FtsQ-type 59 128 2.8E-19 T 29-03-2018 IPR013685 POTRA domain, FtsQ-type MC49_RS09040 c5af74729591220cb0e5fab4dabb1ff4 151 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 114 138 - T 29-03-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site MC49_RS09040 c5af74729591220cb0e5fab4dabb1ff4 151 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 28 150 29.763 T 29-03-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 MC49_RS09040 c5af74729591220cb0e5fab4dabb1ff4 151 SUPERFAMILY SSF109635 9 110 1.14E-36 T 29-03-2018 MC49_RS09040 c5af74729591220cb0e5fab4dabb1ff4 151 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 111 143 3.1E-10 T 29-03-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 MC49_RS09040 c5af74729591220cb0e5fab4dabb1ff4 151 SUPERFAMILY SSF57716 111 149 5.7E-10 T 29-03-2018 MC49_RS09040 c5af74729591220cb0e5fab4dabb1ff4 151 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 32 140 7.4E-51 T 29-03-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 MC49_RS09040 c5af74729591220cb0e5fab4dabb1ff4 151 PRINTS PR00618 DksA/TraR zinc finger signature 126 138 9.9E-5 T 29-03-2018 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria MC49_RS09040 c5af74729591220cb0e5fab4dabb1ff4 151 PRINTS PR00618 DksA/TraR zinc finger signature 114 125 9.9E-5 T 29-03-2018 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria MC49_RS16835 28f3da3d34d646df1205c49bbe33a235 402 SUPERFAMILY SSF55920 153 391 8.51E-27 T 29-03-2018 IPR000994 Peptidase M24 MC49_RS16835 28f3da3d34d646df1205c49bbe33a235 402 Gene3D G3DSA:3.40.350.10 9 158 0.0012 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal MC49_RS16835 28f3da3d34d646df1205c49bbe33a235 402 Gene3D G3DSA:3.90.230.10 159 400 1.0E-26 T 29-03-2018 MC49_RS16835 28f3da3d34d646df1205c49bbe33a235 402 Pfam PF00557 Metallopeptidase family M24 161 369 5.7E-18 T 29-03-2018 IPR000994 Peptidase M24 MC49_RS18405 f1388dc586e2875d87c2e21c096209e1 304 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 10 304 62.505 T 29-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 MC49_RS18405 f1388dc586e2875d87c2e21c096209e1 304 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 15 303 1.8E-117 T 29-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 MC49_RS18405 f1388dc586e2875d87c2e21c096209e1 304 SUPERFAMILY SSF56349 13 295 2.03E-57 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MC49_RS18405 f1388dc586e2875d87c2e21c096209e1 304 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 15 96 7.0E-24 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 MC49_RS18405 f1388dc586e2875d87c2e21c096209e1 304 Gene3D G3DSA:1.10.150.130 10 117 5.4E-23 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal MC49_RS18405 f1388dc586e2875d87c2e21c096209e1 304 Gene3D G3DSA:1.10.443.10 118 298 6.7E-48 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MC49_RS18405 f1388dc586e2875d87c2e21c096209e1 304 Pfam PF00589 Phage integrase family 119 290 3.1E-53 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MC49_RS18405 f1388dc586e2875d87c2e21c096209e1 304 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 12 304 57.592 T 29-03-2018 IPR023009 Tyrosine recombinase XerC/XerD MC49_RS13765 0ec26670583eb50bfc8cb21640dc5f78 240 Gene3D G3DSA:1.10.357.10 92 181 2.4E-9 T 29-03-2018 MC49_RS13765 0ec26670583eb50bfc8cb21640dc5f78 240 Gene3D G3DSA:1.10.10.60 17 91 5.1E-17 T 29-03-2018 MC49_RS13765 0ec26670583eb50bfc8cb21640dc5f78 240 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 60 5.0E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS13765 0ec26670583eb50bfc8cb21640dc5f78 240 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 68 91 5.0E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS13765 0ec26670583eb50bfc8cb21640dc5f78 240 Pfam PF00440 Bacterial regulatory proteins, tetR family 47 93 7.3E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS13765 0ec26670583eb50bfc8cb21640dc5f78 240 SUPERFAMILY SSF46689 34 103 8.21E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS10880 1f9449deda06f0a38f7b9307a48b8196 245 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 2 237 2.0E-75 T 29-03-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 MC49_RS10880 1f9449deda06f0a38f7b9307a48b8196 245 Pfam PF00977 Histidine biosynthesis protein 1 234 1.3E-73 T 29-03-2018 IPR006062 Histidine biosynthesis GO:0000105 MC49_RS10880 1f9449deda06f0a38f7b9307a48b8196 245 Gene3D G3DSA:3.20.20.70 1 245 5.6E-54 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS10880 1f9449deda06f0a38f7b9307a48b8196 245 SUPERFAMILY SSF51366 1 244 3.45E-64 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MC49_RS10880 1f9449deda06f0a38f7b9307a48b8196 245 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 1 241 34.716 T 29-03-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 MC49_RS18925 c33fab60d0903cab5210b68a5af19df7 359 SUPERFAMILY SSF56235 26 330 1.85E-100 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MC49_RS18925 c33fab60d0903cab5210b68a5af19df7 359 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 26 312 4.3E-48 T 29-03-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal MC49_RS18925 c33fab60d0903cab5210b68a5af19df7 359 Gene3D G3DSA:3.60.60.10 23 345 2.5E-105 T 29-03-2018 MC49_RS10045 b25a1180d77702db6d69386f0f991e4e 706 SUPERFAMILY SSF48168 6 166 1.44E-57 T 29-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MC49_RS10045 b25a1180d77702db6d69386f0f991e4e 706 TIGRFAM TIGR04170 RNR_1b_NrdE: ribonucleoside-diphosphate reductase, class 1b, alpha subunit 7 706 0.0 T 29-03-2018 IPR026459 Ribonucleotide reductase, class 1b, subunit NrdE KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MC49_RS10045 b25a1180d77702db6d69386f0f991e4e 706 Pfam PF08343 Ribonucleotide reductase N-terminal 8 89 4.0E-31 T 29-03-2018 IPR013554 Ribonucleotide reductase N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MC49_RS10045 b25a1180d77702db6d69386f0f991e4e 706 SUPERFAMILY SSF51998 167 690 3.97E-185 T 29-03-2018 MC49_RS10045 b25a1180d77702db6d69386f0f991e4e 706 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 92 163 2.6E-11 T 29-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MC49_RS10045 b25a1180d77702db6d69386f0f991e4e 706 Gene3D G3DSA:3.20.70.20 70 693 8.2E-160 T 29-03-2018 MC49_RS10045 b25a1180d77702db6d69386f0f991e4e 706 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 95 688 4.8E-157 T 29-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MC49_RS10045 b25a1180d77702db6d69386f0f991e4e 706 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 558 580 - T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MC49_RS10045 b25a1180d77702db6d69386f0f991e4e 706 PRINTS PR01183 Ribonucleotide reductase large chain signature 243 262 3.2E-34 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MC49_RS10045 b25a1180d77702db6d69386f0f991e4e 706 PRINTS PR01183 Ribonucleotide reductase large chain signature 569 596 3.2E-34 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MC49_RS10045 b25a1180d77702db6d69386f0f991e4e 706 PRINTS PR01183 Ribonucleotide reductase large chain signature 418 441 3.2E-34 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MC49_RS10045 b25a1180d77702db6d69386f0f991e4e 706 PRINTS PR01183 Ribonucleotide reductase large chain signature 374 385 3.2E-34 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MC49_RS10045 b25a1180d77702db6d69386f0f991e4e 706 PRINTS PR01183 Ribonucleotide reductase large chain signature 485 508 3.2E-34 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MC49_RS10045 b25a1180d77702db6d69386f0f991e4e 706 PRINTS PR01183 Ribonucleotide reductase large chain signature 457 479 3.2E-34 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MC49_RS10045 b25a1180d77702db6d69386f0f991e4e 706 Pfam PF02867 Ribonucleotide reductase, barrel domain 168 685 3.0E-142 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MC49_RS05135 afdfc1cb089a41a40ff09ed4cc4ae1c3 208 SUPERFAMILY SSF53335 7 206 5.06E-40 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS05135 afdfc1cb089a41a40ff09ed4cc4ae1c3 208 PIRSF PIRSF003078 1 208 2.0E-62 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MC49_RS05135 afdfc1cb089a41a40ff09ed4cc4ae1c3 208 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 16 204 28.606 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MC49_RS05135 afdfc1cb089a41a40ff09ed4cc4ae1c3 208 Pfam PF02527 rRNA small subunit methyltransferase G 23 203 1.0E-60 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MC49_RS05135 afdfc1cb089a41a40ff09ed4cc4ae1c3 208 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 29 206 8.7E-58 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MC49_RS05135 afdfc1cb089a41a40ff09ed4cc4ae1c3 208 Gene3D G3DSA:3.40.50.150 4 208 9.4E-35 T 29-03-2018 MC49_RS11760 eb67349692ec9ccbcd493cfb1977dcca 232 Pfam PF03167 Uracil DNA glycosylase superfamily 54 209 4.1E-24 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MC49_RS11760 eb67349692ec9ccbcd493cfb1977dcca 232 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 57 66 - T 29-03-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MC49_RS11760 eb67349692ec9ccbcd493cfb1977dcca 232 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 4 221 39.788 T 29-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MC49_RS11760 eb67349692ec9ccbcd493cfb1977dcca 232 SMART SM00987 49 210 6.6E-41 T 29-03-2018 MC49_RS11760 eb67349692ec9ccbcd493cfb1977dcca 232 Gene3D G3DSA:3.40.470.10 1 229 3.0E-102 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MC49_RS11760 eb67349692ec9ccbcd493cfb1977dcca 232 SUPERFAMILY SSF52141 5 221 8.72E-94 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MC49_RS11760 eb67349692ec9ccbcd493cfb1977dcca 232 SMART SM00986 49 210 6.6E-41 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MC49_RS11760 eb67349692ec9ccbcd493cfb1977dcca 232 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 6 214 1.7E-85 T 29-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MC49_RS03555 129ad6a127eccf68961af8cc3c11305f 129 ProSitePatterns PS01048 Ribosomal protein S6 signature. 43 52 - T 29-03-2018 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 MC49_RS03555 129ad6a127eccf68961af8cc3c11305f 129 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 94 5.3E-38 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS03555 129ad6a127eccf68961af8cc3c11305f 129 Pfam PF01250 Ribosomal protein S6 3 91 1.2E-28 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS03555 129ad6a127eccf68961af8cc3c11305f 129 Gene3D G3DSA:3.30.70.60 1 100 3.8E-31 T 29-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 MC49_RS03555 129ad6a127eccf68961af8cc3c11305f 129 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 94 22.163 T 29-03-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 MC49_RS03555 129ad6a127eccf68961af8cc3c11305f 129 SUPERFAMILY SSF54995 1 103 1.7E-38 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS12810 9fc55681865ec0d98188b7d075b3d3e5 88 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 41 49 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MC49_RS12810 9fc55681865ec0d98188b7d075b3d3e5 88 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 18 80 8.0E-9 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MC49_RS12810 9fc55681865ec0d98188b7d075b3d3e5 88 Gene3D G3DSA:3.10.20.30 2 88 2.0E-11 T 29-03-2018 IPR012675 Beta-grasp domain MC49_RS12810 9fc55681865ec0d98188b7d075b3d3e5 88 SUPERFAMILY SSF54292 6 88 1.7E-17 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MC49_RS15335 b3a6dadb33fabe8e48c44e4c8546dfc0 886 Pfam PF00465 Iron-containing alcohol dehydrogenase 457 851 7.9E-114 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 MC49_RS15335 b3a6dadb33fabe8e48c44e4c8546dfc0 886 SUPERFAMILY SSF56796 449 867 1.15E-117 T 29-03-2018 MC49_RS15335 b3a6dadb33fabe8e48c44e4c8546dfc0 886 PIRSF PIRSF000111 1 866 0.0 T 29-03-2018 IPR012079 Bifunctional aldehyde-alcohol dehydrogenase GO:0004022|GO:0006066|GO:0008774|GO:0015976|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 MC49_RS15335 b3a6dadb33fabe8e48c44e4c8546dfc0 886 Gene3D G3DSA:3.40.309.10 230 403 1.4E-23 T 29-03-2018 MC49_RS15335 b3a6dadb33fabe8e48c44e4c8546dfc0 886 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 720 740 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 MC49_RS15335 b3a6dadb33fabe8e48c44e4c8546dfc0 886 Pfam PF00171 Aldehyde dehydrogenase family 5 268 2.9E-24 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MC49_RS15335 b3a6dadb33fabe8e48c44e4c8546dfc0 886 SUPERFAMILY SSF53720 6 453 5.11E-81 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MC49_RS15335 b3a6dadb33fabe8e48c44e4c8546dfc0 886 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 632 660 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 MC49_RS15335 b3a6dadb33fabe8e48c44e4c8546dfc0 886 Gene3D G3DSA:3.40.605.10 1 229 4.9E-31 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MC49_RS15335 b3a6dadb33fabe8e48c44e4c8546dfc0 886 Gene3D G3DSA:1.20.1090.10 644 868 3.3E-59 T 29-03-2018 MC49_RS15335 b3a6dadb33fabe8e48c44e4c8546dfc0 886 Gene3D G3DSA:3.40.50.1970 430 643 3.3E-51 T 29-03-2018 MC49_RS15150 57c23dc4e6f9105286b6c30819623b67 516 Gene3D G3DSA:3.60.120.10 3 516 1.6E-154 T 29-03-2018 IPR005801 ADC synthase GO:0009058 MC49_RS15150 57c23dc4e6f9105286b6c30819623b67 516 PIRSF PIRSF001373 3 516 9.8E-232 T 29-03-2018 IPR005257 Anthranilate synthase component I, TrpE-like, bacterial GO:0004049|GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MC49_RS15150 57c23dc4e6f9105286b6c30819623b67 516 Pfam PF04715 Anthranilate synthase component I, N terminal region 20 186 2.9E-15 T 29-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MC49_RS15150 57c23dc4e6f9105286b6c30819623b67 516 TIGRFAM TIGR00565 trpE_proteo: anthranilate synthase component I 17 511 1.0E-214 T 29-03-2018 IPR005257 Anthranilate synthase component I, TrpE-like, bacterial GO:0004049|GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MC49_RS15150 57c23dc4e6f9105286b6c30819623b67 516 Pfam PF00425 chorismate binding enzyme 238 498 3.4E-85 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal MC49_RS15150 57c23dc4e6f9105286b6c30819623b67 516 SUPERFAMILY SSF56322 11 511 4.84E-156 T 29-03-2018 IPR005801 ADC synthase GO:0009058 MC49_RS15150 57c23dc4e6f9105286b6c30819623b67 516 PRINTS PR00095 Anthranilate synthase component I signature 440 454 2.0E-20 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MC49_RS15150 57c23dc4e6f9105286b6c30819623b67 516 PRINTS PR00095 Anthranilate synthase component I signature 455 469 2.0E-20 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MC49_RS15150 57c23dc4e6f9105286b6c30819623b67 516 PRINTS PR00095 Anthranilate synthase component I signature 360 373 2.0E-20 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MC49_RS15150 57c23dc4e6f9105286b6c30819623b67 516 PRINTS PR00095 Anthranilate synthase component I signature 346 359 2.0E-20 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MC49_RS11095 d7484c3be891171f47ff40ff7c556a74 246 TIGRFAM TIGR02493 PFLA: pyruvate formate-lyase 1-activating enzyme 6 239 4.4E-108 T 29-03-2018 IPR012838 Pyruvate formate-lyase activating enzyme GO:0043365|GO:0055114 MC49_RS11095 d7484c3be891171f47ff40ff7c556a74 246 ProSitePatterns PS01087 Radical activating enzymes signature. 18 39 - T 29-03-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 MC49_RS11095 d7484c3be891171f47ff40ff7c556a74 246 SUPERFAMILY SSF102114 23 215 5.49E-23 T 29-03-2018 MC49_RS11095 d7484c3be891171f47ff40ff7c556a74 246 Pfam PF04055 Radical SAM superfamily 24 181 2.1E-30 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MC49_RS11095 d7484c3be891171f47ff40ff7c556a74 246 Pfam PF13353 4Fe-4S single cluster domain 16 111 2.3E-18 T 29-03-2018 MC49_RS11095 d7484c3be891171f47ff40ff7c556a74 246 PIRSF PIRSF000371 2 47 5.7E-11 T 29-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 MC49_RS11095 d7484c3be891171f47ff40ff7c556a74 246 PIRSF PIRSF000371 45 246 2.3E-47 T 29-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 MC49_RS11095 d7484c3be891171f47ff40ff7c556a74 246 Gene3D G3DSA:3.80.30.10 68 246 1.4E-37 T 29-03-2018 MC49_RS14495 36b6004494f74cb92c7326059e544120 373 Pfam PF08007 Cupin superfamily protein 10 310 1.9E-98 T 29-03-2018 IPR003347 JmjC domain MC49_RS14495 36b6004494f74cb92c7326059e544120 373 Gene3D G3DSA:2.60.120.650 4 206 1.0E-28 T 29-03-2018 MC49_RS14495 36b6004494f74cb92c7326059e544120 373 SMART SM00558 92 215 2.5E-6 T 29-03-2018 IPR003347 JmjC domain MC49_RS14495 36b6004494f74cb92c7326059e544120 373 SUPERFAMILY SSF51197 6 292 4.53E-76 T 29-03-2018 MC49_RS16445 ceffe45c27754692e9071f51dbb141d4 285 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 15 284 55.34 T 29-03-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 MC49_RS16445 ceffe45c27754692e9071f51dbb141d4 285 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 123 143 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 MC49_RS16445 ceffe45c27754692e9071f51dbb141d4 285 Gene3D G3DSA:3.90.226.10 8 224 4.1E-62 T 29-03-2018 MC49_RS16445 ceffe45c27754692e9071f51dbb141d4 285 Gene3D G3DSA:1.10.12.10 225 273 6.4E-14 T 29-03-2018 IPR014748 Crontonase, C-terminal MC49_RS16445 ceffe45c27754692e9071f51dbb141d4 285 SUPERFAMILY SSF52096 17 280 7.68E-78 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MC49_RS16445 ceffe45c27754692e9071f51dbb141d4 285 Pfam PF00378 Enoyl-CoA hydratase/isomerase 31 279 9.5E-79 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MC49_RS16445 ceffe45c27754692e9071f51dbb141d4 285 TIGRFAM TIGR01929 menB: naphthoate synthase 22 281 1.3E-145 T 29-03-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 MC49_RS13240 6a7cf9ff869ef4d50a401d25603436bf 122 Gene3D G3DSA:2.60.40.1180 74 121 6.9E-4 T 29-03-2018 MC49_RS13240 6a7cf9ff869ef4d50a401d25603436bf 122 Gene3D G3DSA:2.60.40.1180 41 73 2.2E-11 T 29-03-2018 MC49_RS13240 6a7cf9ff869ef4d50a401d25603436bf 122 Gene3D G3DSA:2.60.40.1180 1 40 1.5E-17 T 29-03-2018 MC49_RS13240 6a7cf9ff869ef4d50a401d25603436bf 122 Pfam PF08238 Sel1 repeat 29 62 5.3E-9 T 29-03-2018 IPR006597 Sel1-like repeat MC49_RS13240 6a7cf9ff869ef4d50a401d25603436bf 122 Pfam PF08238 Sel1 repeat 1 27 1.2E-4 T 29-03-2018 IPR006597 Sel1-like repeat MC49_RS13240 6a7cf9ff869ef4d50a401d25603436bf 122 Pfam PF08238 Sel1 repeat 77 103 2.8 T 29-03-2018 IPR006597 Sel1-like repeat MC49_RS13240 6a7cf9ff869ef4d50a401d25603436bf 122 SMART SM00671 1 27 5.8 T 29-03-2018 IPR006597 Sel1-like repeat MC49_RS13240 6a7cf9ff869ef4d50a401d25603436bf 122 SMART SM00671 73 108 1.3 T 29-03-2018 IPR006597 Sel1-like repeat MC49_RS13240 6a7cf9ff869ef4d50a401d25603436bf 122 SMART SM00671 28 63 6.9E-11 T 29-03-2018 IPR006597 Sel1-like repeat MC49_RS13240 6a7cf9ff869ef4d50a401d25603436bf 122 SUPERFAMILY SSF81901 1 116 5.23E-21 T 29-03-2018 MC49_RS03885 1d423631dd4ed1a70632da3558b14537 522 Gene3D G3DSA:3.40.50.1100 37 148 4.1E-31 T 29-03-2018 MC49_RS03885 1d423631dd4ed1a70632da3558b14537 522 TIGRFAM TIGR01124 ilvA_2Cterm: threonine ammonia-lyase, biosynthetic 15 512 8.0E-246 T 29-03-2018 IPR005787 Threonine dehydratase, biosynthetic GO:0004794|GO:0009097 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 MC49_RS03885 1d423631dd4ed1a70632da3558b14537 522 Gene3D G3DSA:3.40.50.1100 149 328 8.3E-48 T 29-03-2018 MC49_RS03885 1d423631dd4ed1a70632da3558b14537 522 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 426 512 1.5E-25 T 29-03-2018 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 MC49_RS03885 1d423631dd4ed1a70632da3558b14537 522 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 329 419 1.6E-21 T 29-03-2018 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 MC49_RS03885 1d423631dd4ed1a70632da3558b14537 522 Gene3D G3DSA:3.40.1020.10 338 513 4.6E-67 T 29-03-2018 MC49_RS03885 1d423631dd4ed1a70632da3558b14537 522 SUPERFAMILY SSF55021 420 512 9.16E-25 T 29-03-2018 MC49_RS03885 1d423631dd4ed1a70632da3558b14537 522 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 53 66 - T 29-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 MC49_RS03885 1d423631dd4ed1a70632da3558b14537 522 SUPERFAMILY SSF53686 19 363 3.8E-102 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MC49_RS03885 1d423631dd4ed1a70632da3558b14537 522 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 29 316 1.0E-78 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MC49_RS18685 283321b49f962fc3a2c836f8d3a96bb9 105 Hamap MF_00910 Cell division protein FtsL [ftsL]. 19 102 15.391 T 29-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 MC49_RS18685 283321b49f962fc3a2c836f8d3a96bb9 105 Pfam PF04999 Cell division protein FtsL 8 103 1.1E-32 T 29-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 MC49_RS18685 283321b49f962fc3a2c836f8d3a96bb9 105 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 21 102 4.5E-21 T 29-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 MC49_RS05555 7d7e159556893cce3086682fcb97a824 78 SUPERFAMILY SSF143800 1 77 6.08E-30 T 29-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS05555 7d7e159556893cce3086682fcb97a824 78 Pfam PF00830 Ribosomal L28 family 3 62 2.9E-26 T 29-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS05555 7d7e159556893cce3086682fcb97a824 78 Gene3D G3DSA:2.30.170.40 2 75 7.7E-28 T 29-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS05555 7d7e159556893cce3086682fcb97a824 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 21.212 T 29-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS05555 7d7e159556893cce3086682fcb97a824 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 2.8E-28 T 29-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS14210 3a3f03911da4bd7314f9228c4ca0e417 641 Gene3D G3DSA:3.40.50.300 442 638 3.3E-12 T 29-03-2018 MC49_RS14210 3a3f03911da4bd7314f9228c4ca0e417 641 Gene3D G3DSA:3.40.50.300 17 416 4.8E-32 T 29-03-2018 MC49_RS14210 3a3f03911da4bd7314f9228c4ca0e417 641 Pfam PF06733 DEAD_2 177 247 3.1E-5 T 29-03-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 MC49_RS14210 3a3f03911da4bd7314f9228c4ca0e417 641 SUPERFAMILY SSF52540 573 599 4.3E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS14210 3a3f03911da4bd7314f9228c4ca0e417 641 SUPERFAMILY SSF52540 41 88 4.3E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS14210 3a3f03911da4bd7314f9228c4ca0e417 641 SUPERFAMILY SSF52540 477 542 4.3E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS14210 3a3f03911da4bd7314f9228c4ca0e417 641 SMART SM00491 474 603 3.4E-49 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 MC49_RS14210 3a3f03911da4bd7314f9228c4ca0e417 641 SMART SM00487 16 311 0.0028 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MC49_RS14210 3a3f03911da4bd7314f9228c4ca0e417 641 Pfam PF13307 Helicase C-terminal domain 459 616 5.6E-35 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 MC49_RS14210 3a3f03911da4bd7314f9228c4ca0e417 641 Pfam PF00270 DEAD/DEAH box helicase 30 131 3.6E-6 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MC49_RS14210 3a3f03911da4bd7314f9228c4ca0e417 641 SUPERFAMILY SSF52540 14 233 1.95E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS18675 497c53731633b0c63d7f135ec2c5ee41 495 SUPERFAMILY SSF53623 105 336 1.24E-76 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MC49_RS18675 497c53731633b0c63d7f135ec2c5ee41 495 SUPERFAMILY SSF63418 5 104 2.75E-23 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MC49_RS18675 497c53731633b0c63d7f135ec2c5ee41 495 Gene3D G3DSA:3.40.1390.10 2 104 1.8E-23 T 29-03-2018 MC49_RS18675 497c53731633b0c63d7f135ec2c5ee41 495 SUPERFAMILY SSF53244 339 491 6.41E-51 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MC49_RS18675 497c53731633b0c63d7f135ec2c5ee41 495 Gene3D G3DSA:3.40.1190.10 105 342 1.0E-52 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MC49_RS18675 497c53731633b0c63d7f135ec2c5ee41 495 Pfam PF08245 Mur ligase middle domain 114 318 1.9E-50 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MC49_RS18675 497c53731633b0c63d7f135ec2c5ee41 495 Pfam PF02875 Mur ligase family, glutamate ligase domain 339 425 1.7E-25 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MC49_RS18675 497c53731633b0c63d7f135ec2c5ee41 495 Pfam PF01225 Mur ligase family, catalytic domain 25 102 9.8E-13 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MC49_RS18675 497c53731633b0c63d7f135ec2c5ee41 495 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 21 491 8.1E-164 T 29-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 MC49_RS18675 497c53731633b0c63d7f135ec2c5ee41 495 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 4 491 34.904 T 29-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 MC49_RS18675 497c53731633b0c63d7f135ec2c5ee41 495 Gene3D G3DSA:3.90.190.20 343 494 1.4E-47 T 29-03-2018 MC49_RS11080 f49c3a7a371739cd2a08696ea873caa8 447 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 14 138 5.3E-16 T 29-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 MC49_RS11080 f49c3a7a371739cd2a08696ea873caa8 447 Pfam PF16193 AAA C-terminal domain 188 267 7.2E-23 T 29-03-2018 IPR032423 AAA C-terminal domain MC49_RS11080 f49c3a7a371739cd2a08696ea873caa8 447 Gene3D G3DSA:1.20.272.10 252 346 1.3E-37 T 29-03-2018 MC49_RS11080 f49c3a7a371739cd2a08696ea873caa8 447 SUPERFAMILY SSF52540 6 237 1.35E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS11080 f49c3a7a371739cd2a08696ea873caa8 447 Gene3D G3DSA:3.40.50.300 2 153 9.6E-30 T 29-03-2018 MC49_RS11080 f49c3a7a371739cd2a08696ea873caa8 447 SMART SM00382 49 165 1.4E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS11080 f49c3a7a371739cd2a08696ea873caa8 447 Gene3D G3DSA:1.10.8.60 154 243 2.6E-19 T 29-03-2018 MC49_RS11080 f49c3a7a371739cd2a08696ea873caa8 447 Pfam PF12002 MgsA AAA+ ATPase C terminal 268 434 5.2E-65 T 29-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal MC49_RS11080 f49c3a7a371739cd2a08696ea873caa8 447 Gene3D G3DSA:1.10.3710.10 348 447 1.7E-32 T 29-03-2018 MC49_RS11080 f49c3a7a371739cd2a08696ea873caa8 447 SUPERFAMILY SSF48019 252 434 6.23E-72 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 MC49_RS08495 4d6476a146b09f71efee26540ae19ee8 413 SUPERFAMILY SSF51604 163 411 9.56E-77 T 29-03-2018 IPR029065 Enolase C-terminal domain-like MC49_RS08495 4d6476a146b09f71efee26540ae19ee8 413 Gene3D G3DSA:3.20.20.120 165 413 3.5E-32 T 29-03-2018 IPR029065 Enolase C-terminal domain-like MC49_RS08495 4d6476a146b09f71efee26540ae19ee8 413 Pfam PF07476 Methylaspartate ammonia-lyase C-terminus 162 410 2.7E-116 T 29-03-2018 IPR022662 Methylaspartate ammonia-lyase, C-terminal KEGG: 00630+4.3.1.2|KEGG: 00660+4.3.1.2|MetaCyc: PWY-5087|MetaCyc: PWY-6728 MC49_RS08495 4d6476a146b09f71efee26540ae19ee8 413 PIRSF PIRSF017107 1 413 1.4E-225 T 29-03-2018 IPR006395 Methylaspartate ammonia-lyase GO:0050096 KEGG: 00630+4.3.1.2|KEGG: 00660+4.3.1.2|MetaCyc: PWY-5087|MetaCyc: PWY-6728 MC49_RS08495 4d6476a146b09f71efee26540ae19ee8 413 TIGRFAM TIGR01502 B_methylAsp_ase: methylaspartate ammonia-lyase 2 411 1.0E-170 T 29-03-2018 IPR006395 Methylaspartate ammonia-lyase GO:0050096 KEGG: 00630+4.3.1.2|KEGG: 00660+4.3.1.2|MetaCyc: PWY-5087|MetaCyc: PWY-6728 MC49_RS08495 4d6476a146b09f71efee26540ae19ee8 413 SUPERFAMILY SSF54826 1 159 5.81E-62 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MC49_RS08495 4d6476a146b09f71efee26540ae19ee8 413 Pfam PF05034 Methylaspartate ammonia-lyase N-terminus 1 159 7.8E-74 T 29-03-2018 IPR022665 Methylaspartate ammonia-lyase, N-terminal KEGG: 00630+4.3.1.2|KEGG: 00660+4.3.1.2|MetaCyc: PWY-5087|MetaCyc: PWY-6728 MC49_RS08495 4d6476a146b09f71efee26540ae19ee8 413 Gene3D G3DSA:3.30.390.10 2 162 1.3E-63 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MC49_RS13820 681346ef37e402fd608755ebd67e8707 134 TIGRFAM TIGR01550 DOC_P1: death-on-curing family protein 13 107 4.7E-20 T 29-03-2018 IPR006440 Death on curing protein GO:0016301 MC49_RS13820 681346ef37e402fd608755ebd67e8707 134 Gene3D G3DSA:1.10.3290.10 7 129 9.7E-5 T 29-03-2018 IPR003812 Fido domain MC49_RS13820 681346ef37e402fd608755ebd67e8707 134 PIRSF PIRSF018297 2 124 1.7E-35 T 29-03-2018 IPR006440 Death on curing protein GO:0016301 MC49_RS13820 681346ef37e402fd608755ebd67e8707 134 Pfam PF02661 Fic/DOC family 37 82 9.8E-6 T 29-03-2018 IPR003812 Fido domain MC49_RS15315 b5f6f6f7a87cb189ee732bc91601fe9b 274 Gene3D G3DSA:1.10.3720.10 6 263 1.2E-40 T 29-03-2018 MC49_RS15315 b5f6f6f7a87cb189ee732bc91601fe9b 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 271 4.2E-28 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS15315 b5f6f6f7a87cb189ee732bc91601fe9b 274 SUPERFAMILY SSF161098 69 253 1.57E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS15315 b5f6f6f7a87cb189ee732bc91601fe9b 274 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 7 50 3.3E-10 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain MC49_RS06645 7098c1827a72714648fda4cedd7ee9db 123 Gene3D G3DSA:1.10.3830.10 6 118 3.3E-39 T 29-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 MC49_RS06645 7098c1827a72714648fda4cedd7ee9db 123 ProSitePatterns PS01069 Prokaryotic diacylglycerol kinase signature. 69 80 - T 29-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 MC49_RS06645 7098c1827a72714648fda4cedd7ee9db 123 Pfam PF01219 Prokaryotic diacylglycerol kinase 16 116 2.9E-34 T 29-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 MC49_RS10930 a037fcab0d084c87da1400df2248c67c 173 Pfam PF04011 LemA family 7 170 3.6E-23 T 29-03-2018 IPR007156 LemA MC49_RS10930 a037fcab0d084c87da1400df2248c67c 173 Gene3D G3DSA:1.20.1440.20 14 172 8.4E-22 T 29-03-2018 MC49_RS10930 a037fcab0d084c87da1400df2248c67c 173 SUPERFAMILY SSF140478 28 169 3.4E-22 T 29-03-2018 IPR023353 LemA-like domain MC49_RS04380 bc4743eac4ad168c3bdce2c762a82b16 776 SUPERFAMILY SSF53098 323 469 7.08E-50 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MC49_RS04380 bc4743eac4ad168c3bdce2c762a82b16 776 Gene3D G3DSA:1.10.10.650 3 102 8.2E-34 T 29-03-2018 IPR023319 Tex-like protein, HTH domain MC49_RS04380 bc4743eac4ad168c3bdce2c762a82b16 776 Gene3D G3DSA:1.10.3500.10 103 359 6.4E-81 T 29-03-2018 IPR023323 Tex-like domain MC49_RS04380 bc4743eac4ad168c3bdce2c762a82b16 776 Pfam PF00575 S1 RNA binding domain 649 720 2.9E-22 T 29-03-2018 IPR003029 S1 domain GO:0003676 MC49_RS04380 bc4743eac4ad168c3bdce2c762a82b16 776 SUPERFAMILY SSF47781 470 557 7.67E-28 T 29-03-2018 IPR010994 RuvA domain 2-like MC49_RS04380 bc4743eac4ad168c3bdce2c762a82b16 776 Gene3D G3DSA:1.10.3500.10 360 498 6.7E-40 T 29-03-2018 IPR023323 Tex-like domain MC49_RS04380 bc4743eac4ad168c3bdce2c762a82b16 776 SMART SM00732 327 424 1.0E-37 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 MC49_RS04380 bc4743eac4ad168c3bdce2c762a82b16 776 SMART SM00316 649 720 1.7E-24 T 29-03-2018 IPR022967 RNA-binding domain, S1 MC49_RS04380 bc4743eac4ad168c3bdce2c762a82b16 776 SUPERFAMILY SSF50249 637 726 1.04E-24 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS04380 bc4743eac4ad168c3bdce2c762a82b16 776 Pfam PF16921 Tex protein YqgF-like domain 328 451 3.3E-51 T 29-03-2018 IPR032639 Tex protein, YqgF-like domain MC49_RS04380 bc4743eac4ad168c3bdce2c762a82b16 776 Pfam PF12836 Helix-hairpin-helix motif 491 555 4.8E-28 T 29-03-2018 MC49_RS04380 bc4743eac4ad168c3bdce2c762a82b16 776 SUPERFAMILY SSF158832 2 322 1.96E-121 T 29-03-2018 MC49_RS04380 bc4743eac4ad168c3bdce2c762a82b16 776 Gene3D G3DSA:2.40.50.140 643 725 1.6E-24 T 29-03-2018 MC49_RS04380 bc4743eac4ad168c3bdce2c762a82b16 776 Pfam PF09371 Tex-like protein N-terminal domain 10 193 9.6E-68 T 29-03-2018 IPR018974 Tex-like protein, N-terminal MC49_RS04380 bc4743eac4ad168c3bdce2c762a82b16 776 Gene3D G3DSA:1.10.150.310 499 630 7.1E-45 T 29-03-2018 MC49_RS04380 bc4743eac4ad168c3bdce2c762a82b16 776 SUPERFAMILY SSF47781 560 632 1.6E-19 T 29-03-2018 IPR010994 RuvA domain 2-like MC49_RS14125 9437cb71a285008611e8756d408da422 403 SUPERFAMILY SSF53613 100 391 3.74E-64 T 29-03-2018 IPR029056 Ribokinase-like MC49_RS14125 9437cb71a285008611e8756d408da422 403 Pfam PF08220 DeoR-like helix-turn-helix domain 14 64 1.9E-9 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MC49_RS14125 9437cb71a285008611e8756d408da422 403 Pfam PF00294 pfkB family carbohydrate kinase 102 388 1.8E-55 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB MC49_RS14125 9437cb71a285008611e8756d408da422 403 PRINTS PR00990 Ribokinase signature 202 215 7.2E-26 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MC49_RS14125 9437cb71a285008611e8756d408da422 403 PRINTS PR00990 Ribokinase signature 102 123 7.2E-26 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MC49_RS14125 9437cb71a285008611e8756d408da422 403 PRINTS PR00990 Ribokinase signature 270 285 7.2E-26 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MC49_RS14125 9437cb71a285008611e8756d408da422 403 PRINTS PR00990 Ribokinase signature 314 325 7.2E-26 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MC49_RS14125 9437cb71a285008611e8756d408da422 403 PRINTS PR00990 Ribokinase signature 129 148 7.2E-26 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MC49_RS14125 9437cb71a285008611e8756d408da422 403 Hamap MF_01987 Ribokinase [rbsK]. 98 398 21.083 T 29-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 MC49_RS14125 9437cb71a285008611e8756d408da422 403 SUPERFAMILY SSF46785 13 63 2.18E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS14125 9437cb71a285008611e8756d408da422 403 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 28 42 5.5E-5 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MC49_RS14125 9437cb71a285008611e8756d408da422 403 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 42 60 5.5E-5 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MC49_RS14125 9437cb71a285008611e8756d408da422 403 Gene3D G3DSA:1.10.10.10 2 68 6.5E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS14125 9437cb71a285008611e8756d408da422 403 Gene3D G3DSA:3.40.1190.20 94 402 8.2E-63 T 29-03-2018 IPR029056 Ribokinase-like MC49_RS14125 9437cb71a285008611e8756d408da422 403 SMART SM00420 11 62 4.0E-5 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MC49_RS12065 331d785e98945110acb12b2f8825ec57 540 Pfam PF02540 NAD synthase 265 511 2.8E-72 T 29-03-2018 IPR022310 NAD/GMP synthase MC49_RS12065 331d785e98945110acb12b2f8825ec57 540 PIRSF PIRSF006630 2 254 1.3E-78 T 29-03-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 MC49_RS12065 331d785e98945110acb12b2f8825ec57 540 PIRSF PIRSF006630 246 539 8.4E-121 T 29-03-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 MC49_RS12065 331d785e98945110acb12b2f8825ec57 540 Gene3D G3DSA:3.40.50.620 262 539 1.1E-63 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS12065 331d785e98945110acb12b2f8825ec57 540 TIGRFAM TIGR00552 nadE: NAD+ synthetase 271 513 9.8E-59 T 29-03-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 MC49_RS12065 331d785e98945110acb12b2f8825ec57 540 Gene3D G3DSA:3.60.110.10 1 261 1.8E-59 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MC49_RS12065 331d785e98945110acb12b2f8825ec57 540 SUPERFAMILY SSF52402 260 520 9.54E-76 T 29-03-2018 MC49_RS12065 331d785e98945110acb12b2f8825ec57 540 SUPERFAMILY SSF56317 3 241 3.14E-62 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MC49_RS12065 331d785e98945110acb12b2f8825ec57 540 Pfam PF00795 Carbon-nitrogen hydrolase 7 241 4.9E-25 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MC49_RS18640 a40c317b824f6bef2b171933bb1fddca 305 Gene3D G3DSA:3.30.470.20 172 304 1.1E-37 T 29-03-2018 MC49_RS18640 a40c317b824f6bef2b171933bb1fddca 305 SUPERFAMILY SSF56059 97 301 7.07E-57 T 29-03-2018 MC49_RS18640 a40c317b824f6bef2b171933bb1fddca 305 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 3 305 35.416 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MC49_RS18640 a40c317b824f6bef2b171933bb1fddca 305 Pfam PF07478 D-ala D-ala ligase C-terminus 103 301 4.9E-65 T 29-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MC49_RS18640 a40c317b824f6bef2b171933bb1fddca 305 Pfam PF01820 D-ala D-ala ligase N-terminus 4 86 1.2E-16 T 29-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MC49_RS18640 a40c317b824f6bef2b171933bb1fddca 305 PIRSF PIRSF039102 1 49 3.2E-8 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MC49_RS18640 a40c317b824f6bef2b171933bb1fddca 305 PIRSF PIRSF039102 43 305 8.7E-90 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MC49_RS18640 a40c317b824f6bef2b171933bb1fddca 305 Gene3D G3DSA:3.40.50.20 1 96 5.2E-31 T 29-03-2018 MC49_RS18640 a40c317b824f6bef2b171933bb1fddca 305 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 63 74 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MC49_RS18640 a40c317b824f6bef2b171933bb1fddca 305 SUPERFAMILY SSF52440 2 96 3.26E-28 T 29-03-2018 IPR016185 Pre-ATP-grasp domain MC49_RS18640 a40c317b824f6bef2b171933bb1fddca 305 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 247 275 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MC49_RS18640 a40c317b824f6bef2b171933bb1fddca 305 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 4 304 5.5E-105 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MC49_RS18640 a40c317b824f6bef2b171933bb1fddca 305 Gene3D G3DSA:3.30.1490.20 97 171 9.4E-21 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MC49_RS09530 4fdb77f4d698abe5c03476ff0eb3354e 289 Pfam PF00480 ROK family 4 287 2.8E-74 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 MC49_RS09530 4fdb77f4d698abe5c03476ff0eb3354e 289 ProSitePatterns PS01125 ROK family signature. 129 156 - T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 MC49_RS09530 4fdb77f4d698abe5c03476ff0eb3354e 289 Gene3D G3DSA:3.30.420.40 2 118 1.4E-21 T 29-03-2018 MC49_RS09530 4fdb77f4d698abe5c03476ff0eb3354e 289 SUPERFAMILY SSF53067 1 288 6.98E-53 T 29-03-2018 MC49_RS09530 4fdb77f4d698abe5c03476ff0eb3354e 289 Gene3D G3DSA:3.30.420.40 119 289 3.7E-45 T 29-03-2018 MC49_RS10520 64339e2ab6ddca412cd4d02b9f1f4627 649 Pfam PF00149 Calcineurin-like phosphoesterase 25 260 1.8E-9 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MC49_RS10520 64339e2ab6ddca412cd4d02b9f1f4627 649 TIGRFAM TIGR01390 CycNucDiestase: 2',3'-cyclic-nucleotide 2'-phosphodiesterase 23 647 0.0 T 29-03-2018 IPR006294 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase GO:0008663|GO:0009117 KEGG: 00230+3.1.4.16+3.1.3.6|KEGG: 00240+3.1.4.16+3.1.3.6 MC49_RS10520 64339e2ab6ddca412cd4d02b9f1f4627 649 SUPERFAMILY SSF55816 357 598 3.4E-37 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MC49_RS10520 64339e2ab6ddca412cd4d02b9f1f4627 649 Gene3D G3DSA:3.60.21.10 14 378 3.4E-76 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like MC49_RS10520 64339e2ab6ddca412cd4d02b9f1f4627 649 Gene3D G3DSA:3.90.780.10 379 606 4.1E-49 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MC49_RS10520 64339e2ab6ddca412cd4d02b9f1f4627 649 ProSitePatterns PS00785 5'-nucleotidase signature 1. 25 37 - T 29-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MC49_RS10520 64339e2ab6ddca412cd4d02b9f1f4627 649 Pfam PF02872 5'-nucleotidase, C-terminal domain 358 551 3.8E-21 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MC49_RS10520 64339e2ab6ddca412cd4d02b9f1f4627 649 SUPERFAMILY SSF56300 20 353 2.85E-83 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like MC49_RS10520 64339e2ab6ddca412cd4d02b9f1f4627 649 PRINTS PR01607 Apyrase family signature 531 550 4.9E-32 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MC49_RS10520 64339e2ab6ddca412cd4d02b9f1f4627 649 PRINTS PR01607 Apyrase family signature 429 452 4.9E-32 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MC49_RS10520 64339e2ab6ddca412cd4d02b9f1f4627 649 PRINTS PR01607 Apyrase family signature 23 41 4.9E-32 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MC49_RS10520 64339e2ab6ddca412cd4d02b9f1f4627 649 PRINTS PR01607 Apyrase family signature 216 233 4.9E-32 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MC49_RS10520 64339e2ab6ddca412cd4d02b9f1f4627 649 PRINTS PR01607 Apyrase family signature 244 267 4.9E-32 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MC49_RS10520 64339e2ab6ddca412cd4d02b9f1f4627 649 PRINTS PR01607 Apyrase family signature 284 304 4.9E-32 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MC49_RS12000 1495a15cfbcf8f416cabd0bb8be9fd8f 197 SUPERFAMILY SSF46689 9 85 2.36E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS12000 1495a15cfbcf8f416cabd0bb8be9fd8f 197 Gene3D G3DSA:1.10.10.60 1 42 5.5E-15 T 29-03-2018 MC49_RS12000 1495a15cfbcf8f416cabd0bb8be9fd8f 197 Gene3D G3DSA:1.10.357.10 74 197 3.1E-10 T 29-03-2018 MC49_RS12000 1495a15cfbcf8f416cabd0bb8be9fd8f 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 2.3E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS12000 1495a15cfbcf8f416cabd0bb8be9fd8f 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 2.3E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS12000 1495a15cfbcf8f416cabd0bb8be9fd8f 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 67 1.6E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS12000 1495a15cfbcf8f416cabd0bb8be9fd8f 197 Gene3D G3DSA:1.10.260.40 43 73 1.8E-14 T 29-03-2018 MC49_RS17860 eed2daa9700da3f1c49e513ca5c40b1c 615 SUPERFAMILY SSF46600 197 248 7.45E-13 T 29-03-2018 IPR001943 UVR domain GO:0005515 MC49_RS17860 eed2daa9700da3f1c49e513ca5c40b1c 615 Gene3D G3DSA:4.10.860.10 187 247 1.8E-14 T 29-03-2018 IPR001943 UVR domain GO:0005515 MC49_RS17860 eed2daa9700da3f1c49e513ca5c40b1c 615 SMART SM00278 593 612 170.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MC49_RS17860 eed2daa9700da3f1c49e513ca5c40b1c 615 SMART SM00278 561 580 0.17 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MC49_RS17860 eed2daa9700da3f1c49e513ca5c40b1c 615 SMART SM00465 21 102 1.6E-23 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily MC49_RS17860 eed2daa9700da3f1c49e513ca5c40b1c 615 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 394 547 1.9E-44 T 29-03-2018 IPR001162 UvrC family homology region MC49_RS17860 eed2daa9700da3f1c49e513ca5c40b1c 615 SUPERFAMILY SSF47781 511 614 4.77E-18 T 29-03-2018 IPR010994 RuvA domain 2-like MC49_RS17860 eed2daa9700da3f1c49e513ca5c40b1c 615 SUPERFAMILY SSF82771 21 104 3.01E-24 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily MC49_RS17860 eed2daa9700da3f1c49e513ca5c40b1c 615 Gene3D G3DSA:1.10.150.20 559 615 2.4E-10 T 29-03-2018 MC49_RS17860 eed2daa9700da3f1c49e513ca5c40b1c 615 Hamap MF_00203 UvrABC system protein C [uvrC]. 8 612 29.435 T 29-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 MC49_RS17860 eed2daa9700da3f1c49e513ca5c40b1c 615 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 13 594 2.2E-219 T 29-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 MC49_RS17860 eed2daa9700da3f1c49e513ca5c40b1c 615 Pfam PF02151 UvrB/uvrC motif 210 243 7.6E-10 T 29-03-2018 IPR001943 UVR domain GO:0005515 MC49_RS17860 eed2daa9700da3f1c49e513ca5c40b1c 615 Gene3D G3DSA:3.40.1440.10 8 105 5.8E-25 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily MC49_RS17860 eed2daa9700da3f1c49e513ca5c40b1c 615 Pfam PF14520 Helix-hairpin-helix domain 563 614 9.1E-6 T 29-03-2018 MC49_RS17860 eed2daa9700da3f1c49e513ca5c40b1c 615 Pfam PF01541 GIY-YIG catalytic domain 22 97 8.7E-13 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily MC49_RS07320 79d9dfef86723266dea14e113ca4ece7 259 PIRSF PIRSF001357 5 254 6.9E-76 T 29-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 MC49_RS07320 79d9dfef86723266dea14e113ca4ece7 259 SUPERFAMILY SSF51569 6 246 3.77E-80 T 29-03-2018 MC49_RS07320 79d9dfef86723266dea14e113ca4ece7 259 Gene3D G3DSA:3.20.20.70 1 259 9.5E-80 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS07320 79d9dfef86723266dea14e113ca4ece7 259 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 11 232 2.9E-79 T 29-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 MC49_RS07320 79d9dfef86723266dea14e113ca4ece7 259 Hamap MF_00592 Deoxyribose-phosphate aldolase [deoC]. 1 259 52.861 T 29-03-2018 IPR023649 Deoxyribose-phosphate aldolase type II GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 MC49_RS07320 79d9dfef86723266dea14e113ca4ece7 259 SMART SM01133 10 246 1.4E-76 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 MC49_RS07320 79d9dfef86723266dea14e113ca4ece7 259 Pfam PF01791 DeoC/LacD family aldolase 12 244 2.0E-48 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 MC49_RS00285 7203e545e447a624a654b9f86a86ab4a 151 ProDom PD033929 YBCN ECS1616 SIMILAR 5'REGION ORF151 RUSA LAMBDOID DLP12 BACTERIOPHAGE PROPHAGE 34 150 5.0E-32 T 29-03-2018 MC49_RS00285 7203e545e447a624a654b9f86a86ab4a 151 Pfam PF05772 NinB protein 14 131 1.3E-6 T 29-03-2018 IPR008711 Recombinase NinB MC49_RS00285 7203e545e447a624a654b9f86a86ab4a 151 Gene3D G3DSA:1.10.3790.10 4 151 2.8E-30 T 29-03-2018 IPR008711 Recombinase NinB MC49_RS00285 7203e545e447a624a654b9f86a86ab4a 151 SUPERFAMILY SSF103370 30 135 7.32E-10 T 29-03-2018 IPR008711 Recombinase NinB MC49_RS12960 e43d28049aa47d6023cea0561bcfa049 147 Gene3D G3DSA:1.10.3790.10 1 138 5.0E-32 T 29-03-2018 IPR008711 Recombinase NinB MC49_RS12960 e43d28049aa47d6023cea0561bcfa049 147 SUPERFAMILY SSF103370 1 132 6.02E-29 T 29-03-2018 IPR008711 Recombinase NinB MC49_RS12960 e43d28049aa47d6023cea0561bcfa049 147 Pfam PF05772 NinB protein 2 132 6.4E-36 T 29-03-2018 IPR008711 Recombinase NinB MC49_RS15270 66230b4181d25ac769caf267b5792350 332 Gene3D G3DSA:3.40.50.300 7 329 2.4E-79 T 29-03-2018 MC49_RS15270 66230b4181d25ac769caf267b5792350 332 Pfam PF00005 ABC transporter 39 190 3.4E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS15270 66230b4181d25ac769caf267b5792350 332 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS15270 66230b4181d25ac769caf267b5792350 332 SUPERFAMILY SSF52540 21 262 4.21E-73 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS15270 66230b4181d25ac769caf267b5792350 332 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 242 309 3.8E-19 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MC49_RS15270 66230b4181d25ac769caf267b5792350 332 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 240 327 9.2E-29 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MC49_RS15270 66230b4181d25ac769caf267b5792350 332 SMART SM00382 47 240 4.6E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS18150 f7fcf18bec60710b31040047044b98cc 334 SMART SM00354 1 71 3.7E-31 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MC49_RS18150 f7fcf18bec60710b31040047044b98cc 334 SUPERFAMILY SSF53822 61 330 4.52E-78 T 29-03-2018 IPR028082 Periplasmic binding protein-like I MC49_RS18150 f7fcf18bec60710b31040047044b98cc 334 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 3.1E-7 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MC49_RS18150 f7fcf18bec60710b31040047044b98cc 334 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 3.1E-7 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MC49_RS18150 f7fcf18bec60710b31040047044b98cc 334 Gene3D G3DSA:1.10.260.40 2 53 4.3E-20 T 29-03-2018 MC49_RS18150 f7fcf18bec60710b31040047044b98cc 334 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.3E-17 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MC49_RS18150 f7fcf18bec60710b31040047044b98cc 334 Gene3D G3DSA:3.40.50.2300 175 309 8.7E-42 T 29-03-2018 MC49_RS18150 f7fcf18bec60710b31040047044b98cc 334 SUPERFAMILY SSF47413 1 59 1.69E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS18150 f7fcf18bec60710b31040047044b98cc 334 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 29-03-2018 MC49_RS18150 f7fcf18bec60710b31040047044b98cc 334 Pfam PF13377 Periplasmic binding protein-like domain 168 329 8.6E-34 T 29-03-2018 MC49_RS18150 f7fcf18bec60710b31040047044b98cc 334 Gene3D G3DSA:3.40.50.2300 54 174 2.2E-30 T 29-03-2018 MC49_RS12070 e74c99f60aa4fb16cae75b47fc3dc3b3 112 PRINTS PR00340 P-II protein signature 52 75 2.7E-44 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MC49_RS12070 e74c99f60aa4fb16cae75b47fc3dc3b3 112 PRINTS PR00340 P-II protein signature 23 41 2.7E-44 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MC49_RS12070 e74c99f60aa4fb16cae75b47fc3dc3b3 112 PRINTS PR00340 P-II protein signature 83 103 2.7E-44 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MC49_RS12070 e74c99f60aa4fb16cae75b47fc3dc3b3 112 PRINTS PR00340 P-II protein signature 2 17 2.7E-44 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MC49_RS12070 e74c99f60aa4fb16cae75b47fc3dc3b3 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 1.4E-44 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MC49_RS12070 e74c99f60aa4fb16cae75b47fc3dc3b3 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 29-03-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 MC49_RS12070 e74c99f60aa4fb16cae75b47fc3dc3b3 112 PIRSF PIRSF039144 1 112 3.6E-58 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MC49_RS12070 e74c99f60aa4fb16cae75b47fc3dc3b3 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 29-03-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 MC49_RS12070 e74c99f60aa4fb16cae75b47fc3dc3b3 112 SMART SM00938 4 105 1.7E-69 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MC49_RS12070 e74c99f60aa4fb16cae75b47fc3dc3b3 112 Gene3D G3DSA:3.30.70.120 1 108 8.0E-50 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MC49_RS12070 e74c99f60aa4fb16cae75b47fc3dc3b3 112 SUPERFAMILY SSF54913 1 112 2.89E-47 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta MC49_RS10050 8ad642dca3a960ba7e6e669710d9e1fc 138 PIRSF PIRSF005087 3 136 2.7E-47 T 29-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI MC49_RS10050 8ad642dca3a960ba7e6e669710d9e1fc 138 TIGRFAM TIGR00333 nrdI: nrdI protein 7 130 4.2E-45 T 29-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI MC49_RS10050 8ad642dca3a960ba7e6e669710d9e1fc 138 SUPERFAMILY SSF52218 3 131 2.32E-21 T 29-03-2018 IPR029039 Flavoprotein-like domain MC49_RS10050 8ad642dca3a960ba7e6e669710d9e1fc 138 Pfam PF07972 NrdI Flavodoxin like 7 122 1.6E-41 T 29-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI MC49_RS10050 8ad642dca3a960ba7e6e669710d9e1fc 138 Gene3D G3DSA:3.40.50.360 5 131 2.7E-21 T 29-03-2018 IPR029039 Flavoprotein-like domain MC49_RS10050 8ad642dca3a960ba7e6e669710d9e1fc 138 Hamap MF_00128 Protein NrdI [nrdI]. 5 132 33.433 T 29-03-2018 IPR020852 Ribonucleotide reductase, class Ib, NrdI, bacterial MC49_RS09145 045d3b7bb9230c4accb998713076835a 284 Pfam PF04976 DMSO reductase anchor subunit (DmsC) 1 282 4.0E-23 T 29-03-2018 IPR007059 DMSO reductase anchor subunit (DmsC) GO:0016021|GO:0019645 MC49_RS09145 045d3b7bb9230c4accb998713076835a 284 Gene3D G3DSA:1.20.1630.10 1 284 2.4E-34 T 29-03-2018 MC49_RS06430 f4b4321a3a355794779077b994195c5e 1408 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 10 1374 19.001 T 29-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS06430 f4b4321a3a355794779077b994195c5e 1408 Pfam PF04998 RNA polymerase Rpb1, domain 5 766 1315 6.1E-78 T 29-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS06430 f4b4321a3a355794779077b994195c5e 1408 Pfam PF05000 RNA polymerase Rpb1, domain 4 674 763 3.0E-18 T 29-03-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS06430 f4b4321a3a355794779077b994195c5e 1408 Pfam PF00623 RNA polymerase Rpb1, domain 2 392 485 9.2E-27 T 29-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS06430 f4b4321a3a355794779077b994195c5e 1408 Pfam PF00623 RNA polymerase Rpb1, domain 2 344 393 1.2E-7 T 29-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS06430 f4b4321a3a355794779077b994195c5e 1408 Pfam PF04997 RNA polymerase Rpb1, domain 1 15 342 1.3E-89 T 29-03-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS06430 f4b4321a3a355794779077b994195c5e 1408 SUPERFAMILY SSF64484 1133 1363 0.0 T 29-03-2018 MC49_RS06430 f4b4321a3a355794779077b994195c5e 1408 SUPERFAMILY SSF64484 16 944 0.0 T 29-03-2018 MC49_RS06430 f4b4321a3a355794779077b994195c5e 1408 Gene3D G3DSA:2.40.50.100 1039 1124 7.7E-11 T 29-03-2018 MC49_RS06430 f4b4321a3a355794779077b994195c5e 1408 Gene3D G3DSA:2.40.50.100 907 1008 1.3E-27 T 29-03-2018 MC49_RS06430 f4b4321a3a355794779077b994195c5e 1408 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 19 1367 0.0 T 29-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS06430 f4b4321a3a355794779077b994195c5e 1408 Gene3D G3DSA:2.40.50.100 1153 1213 1.6E-13 T 29-03-2018 MC49_RS06430 f4b4321a3a355794779077b994195c5e 1408 Gene3D G3DSA:2.40.40.20 346 488 7.0E-40 T 29-03-2018 MC49_RS06430 f4b4321a3a355794779077b994195c5e 1408 SMART SM00663 235 514 9.1E-184 T 29-03-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS06430 f4b4321a3a355794779077b994195c5e 1408 Gene3D G3DSA:2.40.50.100 1009 1038 0.065 T 29-03-2018 MC49_RS06430 f4b4321a3a355794779077b994195c5e 1408 Pfam PF04983 RNA polymerase Rpb1, domain 3 489 644 2.6E-25 T 29-03-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS06345 0a91fc81203aa2b3bfea66753c460c0e 72 Gene3D G3DSA:1.20.5.300 5 50 3.2E-17 T 29-03-2018 MC49_RS06345 0a91fc81203aa2b3bfea66753c460c0e 72 Pfam PF04102 SlyX 6 72 3.9E-24 T 29-03-2018 IPR007236 SlyX MC49_RS06345 0a91fc81203aa2b3bfea66753c460c0e 72 Hamap MF_00715 Protein SlyX [slyX]. 5 72 16.82 T 29-03-2018 IPR007236 SlyX MC49_RS17105 b8a6d0af474efc0a0de9e055a6135a51 317 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 1 317 68.143 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MC49_RS17105 b8a6d0af474efc0a0de9e055a6135a51 317 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 1 317 1.1E-139 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MC49_RS17105 b8a6d0af474efc0a0de9e055a6135a51 317 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 106 183 8.3E-30 T 29-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MC49_RS17105 b8a6d0af474efc0a0de9e055a6135a51 317 Gene3D G3DSA:3.40.47.10 2 161 2.8E-36 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MC49_RS17105 b8a6d0af474efc0a0de9e055a6135a51 317 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 230 316 7.3E-35 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MC49_RS17105 b8a6d0af474efc0a0de9e055a6135a51 317 SUPERFAMILY SSF53901 3 317 6.63E-69 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MC49_RS17105 b8a6d0af474efc0a0de9e055a6135a51 317 Gene3D G3DSA:3.40.47.10 162 317 6.4E-41 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MC49_RS03815 101a6a862b0fd172cf30217f327858c2 357 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 3 341 1.3E-159 T 29-03-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 MC49_RS03815 101a6a862b0fd172cf30217f327858c2 357 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 327 2.7E-98 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS03815 101a6a862b0fd172cf30217f327858c2 357 SUPERFAMILY SSF51735 2 346 2.45E-96 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS03815 101a6a862b0fd172cf30217f327858c2 357 Gene3D G3DSA:3.90.25.10 194 340 8.4E-49 T 29-03-2018 MC49_RS03815 101a6a862b0fd172cf30217f327858c2 357 Gene3D G3DSA:3.40.50.720 1 193 2.2E-42 T 29-03-2018 MC49_RS07025 d40b204ea7de1aeb39a910e0de6a03eb 94 SUPERFAMILY SSF55021 10 79 7.64E-14 T 29-03-2018 MC49_RS07025 d40b204ea7de1aeb39a910e0de6a03eb 94 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 14 77 1.0E-14 T 29-03-2018 MC49_RS07025 d40b204ea7de1aeb39a910e0de6a03eb 94 Gene3D G3DSA:3.30.70.260 1 93 9.2E-15 T 29-03-2018 MC49_RS07025 d40b204ea7de1aeb39a910e0de6a03eb 94 Pfam PF13710 ACT domain 17 77 2.9E-8 T 29-03-2018 MC49_RS14615 6ea4707a2537dec300ea7796d695b737 154 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 17 144 1.7E-49 T 29-03-2018 IPR003791 Protein of unknown function UPF0178 MC49_RS14615 6ea4707a2537dec300ea7796d695b737 154 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 1 147 31.425 T 29-03-2018 IPR003791 Protein of unknown function UPF0178 MC49_RS05865 6fafbbd624bf84afd0639217f032fc28 176 SUPERFAMILY SSF56235 1 171 5.09E-59 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MC49_RS05865 6fafbbd624bf84afd0639217f032fc28 176 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 1 172 42.029 T 29-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 MC49_RS05865 6fafbbd624bf84afd0639217f032fc28 176 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 2 172 3.8E-86 T 29-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 MC49_RS05865 6fafbbd624bf84afd0639217f032fc28 176 Pfam PF00227 Proteasome subunit 2 169 1.7E-23 T 29-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 MC49_RS05865 6fafbbd624bf84afd0639217f032fc28 176 Gene3D G3DSA:3.60.20.10 2 172 5.7E-32 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MC49_RS05865 6fafbbd624bf84afd0639217f032fc28 176 PIRSF PIRSF039093 1 175 2.3E-87 T 29-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 MC49_RS03330 6c88753544c7e6534d810bcb8aa11482 323 Gene3D G3DSA:1.20.1600.10 171 300 1.3E-7 T 29-03-2018 MC49_RS03330 6c88753544c7e6534d810bcb8aa11482 323 SUPERFAMILY SSF111369 36 94 2.62E-6 T 29-03-2018 MC49_RS03330 6c88753544c7e6534d810bcb8aa11482 323 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 40 315 1.3E-17 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MC49_RS03330 6c88753544c7e6534d810bcb8aa11482 323 Gene3D G3DSA:1.10.287.470 106 170 6.0E-11 T 29-03-2018 MC49_RS03330 6c88753544c7e6534d810bcb8aa11482 323 Gene3D G3DSA:2.40.50.100 38 102 1.4E-11 T 29-03-2018 MC49_RS03330 6c88753544c7e6534d810bcb8aa11482 323 SUPERFAMILY SSF111369 106 167 6.93E-6 T 29-03-2018 MC49_RS03330 6c88753544c7e6534d810bcb8aa11482 323 SUPERFAMILY SSF111369 160 263 1.57E-8 T 29-03-2018 MC49_RS00435 0eaf1115ec363244d65110145c9eea79 70 Gene3D G3DSA:3.10.290.10 1 70 3.9E-14 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MC49_RS00435 0eaf1115ec363244d65110145c9eea79 70 SUPERFAMILY SSF55174 8 67 1.13E-19 T 29-03-2018 MC49_RS00435 0eaf1115ec363244d65110145c9eea79 70 Pfam PF13275 S4 domain 8 68 9.2E-25 T 29-03-2018 MC49_RS07660 56bae13def1c5cf48705c1518b2f5bde 232 Pfam PF09335 SNARE associated Golgi protein 48 173 1.4E-19 T 29-03-2018 IPR032816 SNARE associated Golgi protein MC49_RS05065 0543ed176fd5bfb256563f3a7d24f030 471 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 17 428 1.1E-72 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 MC49_RS05065 0543ed176fd5bfb256563f3a7d24f030 471 Gene3D G3DSA:1.20.1250.20 10 197 3.9E-31 T 29-03-2018 MC49_RS05065 0543ed176fd5bfb256563f3a7d24f030 471 SUPERFAMILY SSF103473 13 194 3.01E-64 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS05065 0543ed176fd5bfb256563f3a7d24f030 471 SUPERFAMILY SSF103473 244 451 3.01E-64 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS05065 0543ed176fd5bfb256563f3a7d24f030 471 Gene3D G3DSA:1.20.1250.20 248 464 2.0E-22 T 29-03-2018 MC49_RS05065 0543ed176fd5bfb256563f3a7d24f030 471 PRINTS PR01036 Tetracycline resistance protein TetB signature 135 159 4.7E-9 T 29-03-2018 MC49_RS05065 0543ed176fd5bfb256563f3a7d24f030 471 PRINTS PR01036 Tetracycline resistance protein TetB signature 14 38 4.7E-9 T 29-03-2018 MC49_RS05065 0543ed176fd5bfb256563f3a7d24f030 471 PRINTS PR01036 Tetracycline resistance protein TetB signature 105 125 4.7E-9 T 29-03-2018 MC49_RS05065 0543ed176fd5bfb256563f3a7d24f030 471 PRINTS PR01036 Tetracycline resistance protein TetB signature 396 415 4.7E-9 T 29-03-2018 MC49_RS05065 0543ed176fd5bfb256563f3a7d24f030 471 PRINTS PR01036 Tetracycline resistance protein TetB signature 199 217 4.7E-9 T 29-03-2018 MC49_RS05065 0543ed176fd5bfb256563f3a7d24f030 471 Pfam PF07690 Major Facilitator Superfamily 16 405 9.5E-50 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS17075 19af40b5ea8ffc490723066e260cf578 340 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 1 337 1.4E-114 T 29-03-2018 IPR003770 Endolytic murein transglycosylase MC49_RS17075 19af40b5ea8ffc490723066e260cf578 340 Gene3D G3DSA:3.30.160.60 77 111 1.0E-15 T 29-03-2018 MC49_RS17075 19af40b5ea8ffc490723066e260cf578 340 Gene3D G3DSA:3.30.160.60 306 340 9.5E-16 T 29-03-2018 MC49_RS17075 19af40b5ea8ffc490723066e260cf578 340 Pfam PF02618 YceG-like family 45 331 2.2E-79 T 29-03-2018 IPR003770 Endolytic murein transglycosylase MC49_RS17075 19af40b5ea8ffc490723066e260cf578 340 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 8 335 32.351 T 29-03-2018 IPR003770 Endolytic murein transglycosylase MC49_RS00665 f926e8f8909ffc267b37c718c292cc26 67 Gene3D G3DSA:1.20.1280.40 1 66 4.1E-34 T 29-03-2018 IPR007985 Haemolysin expression modulating, HHA MC49_RS00665 f926e8f8909ffc267b37c718c292cc26 67 SUPERFAMILY SSF68989 1 67 3.14E-31 T 29-03-2018 IPR007985 Haemolysin expression modulating, HHA MC49_RS00665 f926e8f8909ffc267b37c718c292cc26 67 Pfam PF05321 Haemolysin expression modulating protein 8 64 1.2E-33 T 29-03-2018 IPR007985 Haemolysin expression modulating, HHA MC49_RS05705 abbbd3d1282218ab6d70db5c96881733 269 SUPERFAMILY SSF51366 1 250 3.92E-60 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MC49_RS05705 abbbd3d1282218ab6d70db5c96881733 269 Pfam PF00977 Histidine biosynthesis protein 5 230 1.5E-63 T 29-03-2018 IPR006062 Histidine biosynthesis GO:0000105 MC49_RS05705 abbbd3d1282218ab6d70db5c96881733 269 Gene3D G3DSA:3.20.20.70 4 246 4.9E-42 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS11715 6988aac0f5f32e324a6c452a195232f4 257 SUPERFAMILY SSF55781 75 248 2.16E-36 T 29-03-2018 IPR029016 GAF domain-like MC49_RS11715 6988aac0f5f32e324a6c452a195232f4 257 Pfam PF01614 Bacterial transcriptional regulator 122 244 4.4E-20 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal MC49_RS11715 6988aac0f5f32e324a6c452a195232f4 257 Gene3D G3DSA:3.30.450.40 90 254 7.7E-35 T 29-03-2018 IPR029016 GAF domain-like MC49_RS11715 6988aac0f5f32e324a6c452a195232f4 257 SUPERFAMILY SSF46785 10 77 1.19E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS11715 6988aac0f5f32e324a6c452a195232f4 257 Pfam PF09339 IclR helix-turn-helix domain 10 57 5.1E-8 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MC49_RS11715 6988aac0f5f32e324a6c452a195232f4 257 Gene3D G3DSA:1.10.10.10 1 89 2.8E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS11715 6988aac0f5f32e324a6c452a195232f4 257 SMART SM00346 6 88 0.0079 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 MC49_RS16235 82e408eb67742f069f22ae77c83d4b5b 346 SUPERFAMILY SSF55326 7 170 2.39E-53 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MC49_RS16235 82e408eb67742f069f22ae77c83d4b5b 346 SUPERFAMILY SSF56042 171 334 7.78E-62 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MC49_RS16235 82e408eb67742f069f22ae77c83d4b5b 346 Pfam PF00586 AIR synthase related protein, N-terminal domain 57 163 2.4E-16 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MC49_RS16235 82e408eb67742f069f22ae77c83d4b5b 346 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 7 345 46.696 T 29-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MC49_RS16235 82e408eb67742f069f22ae77c83d4b5b 346 Gene3D G3DSA:3.30.1330.10 31 161 3.1E-53 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MC49_RS16235 82e408eb67742f069f22ae77c83d4b5b 346 Gene3D G3DSA:3.90.650.10 171 346 3.2E-60 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MC49_RS16235 82e408eb67742f069f22ae77c83d4b5b 346 Pfam PF02769 AIR synthase related protein, C-terminal domain 176 333 1.1E-36 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MC49_RS16235 82e408eb67742f069f22ae77c83d4b5b 346 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 7 333 1.2E-150 T 29-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MC49_RS14095 53085a4f1a521ec4ff26a0615304ff29 326 Hamap MF_01944 Lipid A biosynthesis myristoyltransferase [lpxM]. 7 313 51.145 T 29-03-2018 IPR011921 Lipid A biosynthesis myristoyltransferase GO:0009103|GO:0009276|GO:0016021|GO:0016747 KEGG: 00540+2.3.1.243|KEGG: 00600+2.3.1.24 MC49_RS14095 53085a4f1a521ec4ff26a0615304ff29 326 TIGRFAM TIGR02208 lipid_A_msbB: lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 13 317 1.2E-125 T 29-03-2018 IPR011921 Lipid A biosynthesis myristoyltransferase GO:0009103|GO:0009276|GO:0016021|GO:0016747 KEGG: 00540+2.3.1.243|KEGG: 00600+2.3.1.24 MC49_RS14095 53085a4f1a521ec4ff26a0615304ff29 326 PIRSF PIRSF026649 13 317 2.9E-93 T 29-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 MC49_RS14095 53085a4f1a521ec4ff26a0615304ff29 326 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 15 308 3.7E-90 T 29-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 MC49_RS19115 4beb91921f87eab53d037fa01a8577e7 388 TIGRFAM TIGR02815 agaS_fam: putative sugar isomerase, AgaS family 12 381 1.8E-160 T 29-03-2018 IPR014180 Sugar isomerase, AgaS GO:0016861 MC49_RS19115 4beb91921f87eab53d037fa01a8577e7 388 Gene3D G3DSA:3.40.50.10490 6 203 2.8E-25 T 29-03-2018 MC49_RS19115 4beb91921f87eab53d037fa01a8577e7 388 SUPERFAMILY SSF53697 14 372 2.23E-48 T 29-03-2018 MC49_RS19115 4beb91921f87eab53d037fa01a8577e7 388 Pfam PF01380 SIS domain 224 353 1.0E-13 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MC49_RS19115 4beb91921f87eab53d037fa01a8577e7 388 Pfam PF01380 SIS domain 49 186 3.0E-19 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MC49_RS19115 4beb91921f87eab53d037fa01a8577e7 388 Gene3D G3DSA:3.40.50.10490 204 375 5.0E-20 T 29-03-2018 MC49_RS03905 d2efe48a4894799849ffb94fee26ec43 548 SUPERFAMILY SSF52467 182 341 9.67E-56 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MC49_RS03905 d2efe48a4894799849ffb94fee26ec43 548 Gene3D G3DSA:3.40.50.970 334 534 1.2E-46 T 29-03-2018 MC49_RS03905 d2efe48a4894799849ffb94fee26ec43 548 Gene3D G3DSA:3.40.50.970 1 184 1.3E-62 T 29-03-2018 MC49_RS03905 d2efe48a4894799849ffb94fee26ec43 548 SUPERFAMILY SSF52518 1 174 1.99E-62 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MC49_RS03905 d2efe48a4894799849ffb94fee26ec43 548 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 411 430 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 MC49_RS03905 d2efe48a4894799849ffb94fee26ec43 548 SUPERFAMILY SSF52518 357 544 4.24E-63 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MC49_RS03905 d2efe48a4894799849ffb94fee26ec43 548 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 164 2.0E-55 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MC49_RS03905 d2efe48a4894799849ffb94fee26ec43 548 Gene3D G3DSA:3.40.50.1220 185 333 4.2E-48 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MC49_RS03905 d2efe48a4894799849ffb94fee26ec43 548 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 187 319 2.4E-42 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MC49_RS03905 d2efe48a4894799849ffb94fee26ec43 548 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 1 546 1.2E-212 T 29-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 MC49_RS03905 d2efe48a4894799849ffb94fee26ec43 548 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 374 522 6.9E-48 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MC49_RS13750 57c13402ab203f469f9ad3f933e4b4aa 145 SUPERFAMILY SSF52402 2 145 1.26E-28 T 29-03-2018 MC49_RS13750 57c13402ab203f469f9ad3f933e4b4aa 145 PIRSF PIRSF006276 1 145 1.9E-20 T 29-03-2018 IPR006015 Universal stress protein A MC49_RS13750 57c13402ab203f469f9ad3f933e4b4aa 145 PRINTS PR01438 Universal stress protein signature 2 20 6.6E-13 T 29-03-2018 IPR006015 Universal stress protein A MC49_RS13750 57c13402ab203f469f9ad3f933e4b4aa 145 PRINTS PR01438 Universal stress protein signature 123 145 6.6E-13 T 29-03-2018 IPR006015 Universal stress protein A MC49_RS13750 57c13402ab203f469f9ad3f933e4b4aa 145 PRINTS PR01438 Universal stress protein signature 106 118 6.6E-13 T 29-03-2018 IPR006015 Universal stress protein A MC49_RS13750 57c13402ab203f469f9ad3f933e4b4aa 145 Gene3D G3DSA:3.40.50.620 1 144 1.1E-27 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS13750 57c13402ab203f469f9ad3f933e4b4aa 145 Pfam PF00582 Universal stress protein family 1 145 2.2E-25 T 29-03-2018 IPR006016 UspA GO:0006950 MC49_RS17665 4e5163ba9290e21ab7511017d763ef56 466 TIGRFAM TIGR01630 psiM2_ORF9: phage uncharacterized protein, C-terminal domain 319 451 2.8E-25 T 29-03-2018 IPR006517 Archaeophage PsiM2, terminase large subunit MC49_RS17665 4e5163ba9290e21ab7511017d763ef56 466 Pfam PF03237 Terminase-like family 61 230 1.9E-9 T 29-03-2018 MC49_RS17665 4e5163ba9290e21ab7511017d763ef56 466 Pfam PF17289 Terminase RNaseH-like domain 308 449 2.3E-13 T 29-03-2018 IPR035421 Terminase, large subunit gp17-like MC49_RS18935 f3cff73ef70b35ab82eda2de268dcc0c 396 Gene3D G3DSA:2.40.50.100 66 144 6.7E-12 T 29-03-2018 MC49_RS18935 f3cff73ef70b35ab82eda2de268dcc0c 396 Gene3D G3DSA:1.10.287.470 145 188 4.2E-8 T 29-03-2018 MC49_RS18935 f3cff73ef70b35ab82eda2de268dcc0c 396 Pfam PF00529 HlyD membrane-fusion protein of T1SS 43 352 1.3E-15 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MC49_RS18935 f3cff73ef70b35ab82eda2de268dcc0c 396 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 69 296 2.4E-16 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MC49_RS18935 f3cff73ef70b35ab82eda2de268dcc0c 396 Gene3D G3DSA:2.40.50.100 214 393 8.1E-8 T 29-03-2018 MC49_RS18935 f3cff73ef70b35ab82eda2de268dcc0c 396 SUPERFAMILY SSF111369 185 273 5.49E-10 T 29-03-2018 MC49_RS18935 f3cff73ef70b35ab82eda2de268dcc0c 396 TIGRFAM TIGR00998 8a0101: efflux pump membrane protein 26 351 2.0E-123 T 29-03-2018 IPR005694 Efflux pump membrane protein Emr GO:0006855|GO:0015238 MC49_RS18935 f3cff73ef70b35ab82eda2de268dcc0c 396 SUPERFAMILY SSF111369 144 191 1.7E-6 T 29-03-2018 MC49_RS18935 f3cff73ef70b35ab82eda2de268dcc0c 396 SUPERFAMILY SSF111369 67 115 1.7E-6 T 29-03-2018 MC49_RS15915 3d939db57411f2bdf85891828cb0b7b8 116 Pfam PF00892 EamA-like transporter family 3 112 1.1E-9 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MC49_RS15915 3d939db57411f2bdf85891828cb0b7b8 116 SUPERFAMILY SSF103481 38 113 1.57E-13 T 29-03-2018 MC49_RS15915 3d939db57411f2bdf85891828cb0b7b8 116 Hamap MF_01869 Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE [arnE]. 4 116 28.268 T 29-03-2018 IPR022883 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase, subunit ArnE MC49_RS02940 6b4c793b5ada918b7acf8062c363a6e7 225 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 1 225 1.3E-116 T 29-03-2018 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 KEGG: 00910+1.7.99.4 MC49_RS02940 6b4c793b5ada918b7acf8062c363a6e7 225 Pfam PF02665 Nitrate reductase gamma subunit 5 224 3.5E-82 T 29-03-2018 IPR023234 NarG-like domain MC49_RS02940 6b4c793b5ada918b7acf8062c363a6e7 225 SUPERFAMILY SSF103501 1 224 2.09E-72 T 29-03-2018 IPR023234 NarG-like domain MC49_RS02940 6b4c793b5ada918b7acf8062c363a6e7 225 Gene3D G3DSA:1.20.950.20 1 216 2.6E-45 T 29-03-2018 MC49_RS14925 38bd8e60da5dc717d6145ebe696968d3 387 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 20 387 5.0E-147 T 29-03-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 MC49_RS14925 38bd8e60da5dc717d6145ebe696968d3 387 ProSitePatterns PS00480 Citrate synthase signature. 270 282 - T 29-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 MC49_RS14925 38bd8e60da5dc717d6145ebe696968d3 387 PRINTS PR00143 Citrate synthase signature 320 336 8.6E-35 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MC49_RS14925 38bd8e60da5dc717d6145ebe696968d3 387 PRINTS PR00143 Citrate synthase signature 138 151 8.6E-35 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MC49_RS14925 38bd8e60da5dc717d6145ebe696968d3 387 PRINTS PR00143 Citrate synthase signature 263 283 8.6E-35 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MC49_RS14925 38bd8e60da5dc717d6145ebe696968d3 387 PRINTS PR00143 Citrate synthase signature 340 354 8.6E-35 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MC49_RS14925 38bd8e60da5dc717d6145ebe696968d3 387 PRINTS PR00143 Citrate synthase signature 210 238 8.6E-35 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MC49_RS14925 38bd8e60da5dc717d6145ebe696968d3 387 PRINTS PR00143 Citrate synthase signature 188 203 8.6E-35 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MC49_RS14925 38bd8e60da5dc717d6145ebe696968d3 387 Pfam PF00285 Citrate synthase, C-terminal domain 21 369 1.4E-109 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MC49_RS14925 38bd8e60da5dc717d6145ebe696968d3 387 Gene3D G3DSA:1.10.580.10 27 367 1.0E-77 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain MC49_RS14925 38bd8e60da5dc717d6145ebe696968d3 387 PIRSF PIRSF001369 13 387 1.3E-104 T 29-03-2018 IPR024176 Citrate synthase, bacterial-type MC49_RS14925 38bd8e60da5dc717d6145ebe696968d3 387 SUPERFAMILY SSF48256 21 381 2.09E-118 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 MC49_RS14105 ba9936048fb36d3a3af6d7306263b8e7 282 Gene3D G3DSA:3.40.50.10490 94 279 3.8E-35 T 29-03-2018 MC49_RS14105 ba9936048fb36d3a3af6d7306263b8e7 282 Pfam PF01380 SIS domain 125 252 3.7E-25 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MC49_RS14105 ba9936048fb36d3a3af6d7306263b8e7 282 SUPERFAMILY SSF53697 95 280 2.07E-41 T 29-03-2018 MC49_RS14105 ba9936048fb36d3a3af6d7306263b8e7 282 Pfam PF01418 Helix-turn-helix domain, rpiR family 1 76 3.7E-26 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 MC49_RS14105 ba9936048fb36d3a3af6d7306263b8e7 282 Gene3D G3DSA:1.10.10.10 1 93 1.1E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS14105 ba9936048fb36d3a3af6d7306263b8e7 282 SUPERFAMILY SSF46689 1 80 5.91E-21 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS14170 6d7b1e1ee7ab8c3f636a7852371c9b17 293 Gene3D G3DSA:3.20.20.70 1 291 2.6E-64 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS14170 6d7b1e1ee7ab8c3f636a7852371c9b17 293 SMART SM01133 51 259 6.1E-23 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 MC49_RS14170 6d7b1e1ee7ab8c3f636a7852371c9b17 293 SUPERFAMILY SSF51569 35 275 6.96E-61 T 29-03-2018 MC49_RS14170 6d7b1e1ee7ab8c3f636a7852371c9b17 293 Pfam PF01791 DeoC/LacD family aldolase 52 258 3.8E-16 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 MC49_RS14170 6d7b1e1ee7ab8c3f636a7852371c9b17 293 PIRSF PIRSF038992 31 289 9.8E-77 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 MC49_RS14170 6d7b1e1ee7ab8c3f636a7852371c9b17 293 Hamap MF_02052 3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase [lsrF]. 1 291 75.442 T 29-03-2018 IPR033673 3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase GO:0016747 KEGG: 00600+2.3.1.24 MC49_RS10560 fbd75a5e9d9073d0f918182116187c6a 273 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 267 5.8E-65 T 29-03-2018 IPR023214 HAD-like domain MC49_RS10560 fbd75a5e9d9073d0f918182116187c6a 273 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 240 1.1E-24 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 MC49_RS10560 fbd75a5e9d9073d0f918182116187c6a 273 ProSitePatterns PS01229 Hypothetical cof family signature 2. 221 243 - T 29-03-2018 MC49_RS10560 fbd75a5e9d9073d0f918182116187c6a 273 Gene3D G3DSA:3.40.50.1000 1 273 4.8E-43 T 29-03-2018 IPR023214 HAD-like domain MC49_RS10560 fbd75a5e9d9073d0f918182116187c6a 273 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 267 2.0E-63 T 29-03-2018 IPR000150 Cof family GO:0016787 MC49_RS10560 fbd75a5e9d9073d0f918182116187c6a 273 SUPERFAMILY SSF56784 1 272 5.01E-67 T 29-03-2018 IPR023214 HAD-like domain MC49_RS13865 d2e6b949fe470ef7c7e0a96ec8e9387a 488 PIRSF PIRSF006247 2 486 2.7E-158 T 29-03-2018 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 MC49_RS13865 d2e6b949fe470ef7c7e0a96ec8e9387a 488 Pfam PF02386 Cation transport protein 42 480 8.7E-88 T 29-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 MC49_RS13865 d2e6b949fe470ef7c7e0a96ec8e9387a 488 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 86 469 7.7E-108 T 29-03-2018 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 MC49_RS07820 3d2ba72dcef95a769ad54e2fe480aa3c 968 SUPERFAMILY SSF52540 480 644 3.28E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS07820 3d2ba72dcef95a769ad54e2fe480aa3c 968 SUPERFAMILY SSF52540 273 337 3.28E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS07820 3d2ba72dcef95a769ad54e2fe480aa3c 968 SUPERFAMILY SSF52540 125 377 7.83E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS07820 3d2ba72dcef95a769ad54e2fe480aa3c 968 Pfam PF00271 Helicase conserved C-terminal domain 492 601 1.2E-15 T 29-03-2018 IPR001650 Helicase, C-terminal MC49_RS07820 3d2ba72dcef95a769ad54e2fe480aa3c 968 Pfam PF12137 RNA polymerase recycling family C-terminal 605 965 2.8E-152 T 29-03-2018 IPR022737 RNA polymerase recycling, bacterial, C-terminal GO:0016817 MC49_RS07820 3d2ba72dcef95a769ad54e2fe480aa3c 968 Gene3D G3DSA:3.40.50.10810 155 390 5.7E-26 T 29-03-2018 MC49_RS07820 3d2ba72dcef95a769ad54e2fe480aa3c 968 Hamap MF_01821 RNA polymerase-associated protein RapA [rapA]. 1 966 28.888 T 29-03-2018 IPR023949 RNA polymerase-associated protein RapA GO:0006355 MC49_RS07820 3d2ba72dcef95a769ad54e2fe480aa3c 968 Gene3D G3DSA:3.40.50.300 483 639 6.6E-22 T 29-03-2018 MC49_RS07820 3d2ba72dcef95a769ad54e2fe480aa3c 968 SMART SM00490 517 601 3.8E-16 T 29-03-2018 IPR001650 Helicase, C-terminal MC49_RS07820 3d2ba72dcef95a769ad54e2fe480aa3c 968 Pfam PF00176 SNF2 family N-terminal domain 174 442 4.9E-17 T 29-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 MC49_RS07820 3d2ba72dcef95a769ad54e2fe480aa3c 968 SMART SM00487 150 342 6.9E-20 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MC49_RS05905 3e45e20f2d7e58efffc5cc54ac7dc321 877 SUPERFAMILY SSF51621 6 877 0.0 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MC49_RS05905 3e45e20f2d7e58efffc5cc54ac7dc321 877 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 1 877 18.396 T 29-03-2018 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MC49_RS05905 3e45e20f2d7e58efffc5cc54ac7dc321 877 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 133 144 - T 29-03-2018 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MC49_RS05905 3e45e20f2d7e58efffc5cc54ac7dc321 877 Pfam PF00311 Phosphoenolpyruvate carboxylase 128 877 1.0E-293 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MC49_RS05905 3e45e20f2d7e58efffc5cc54ac7dc321 877 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 185 201 6.0E-69 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MC49_RS05905 3e45e20f2d7e58efffc5cc54ac7dc321 877 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 244 259 6.0E-69 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MC49_RS05905 3e45e20f2d7e58efffc5cc54ac7dc321 877 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 575 604 6.0E-69 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MC49_RS05905 3e45e20f2d7e58efffc5cc54ac7dc321 877 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 707 733 6.0E-69 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MC49_RS05905 3e45e20f2d7e58efffc5cc54ac7dc321 877 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 132 145 6.0E-69 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MC49_RS05905 3e45e20f2d7e58efffc5cc54ac7dc321 877 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 384 404 6.0E-69 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MC49_RS05905 3e45e20f2d7e58efffc5cc54ac7dc321 877 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 533 553 6.0E-69 T 29-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MC49_RS05905 3e45e20f2d7e58efffc5cc54ac7dc321 877 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 535 547 - T 29-03-2018 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MC49_RS05905 3e45e20f2d7e58efffc5cc54ac7dc321 877 Gene3D G3DSA:1.20.1440.90 273 386 6.8E-27 T 29-03-2018 MC49_RS04210 78e51ff4c9e567284eaa03e08b9c4de8 326 SUPERFAMILY SSF55681 71 268 1.24E-58 T 29-03-2018 MC49_RS04210 78e51ff4c9e567284eaa03e08b9c4de8 326 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 81 317 3.9E-69 T 29-03-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 MC49_RS04210 78e51ff4c9e567284eaa03e08b9c4de8 326 Pfam PF03099 Biotin/lipoate A/B protein ligase family 84 208 8.8E-21 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 MC49_RS04210 78e51ff4c9e567284eaa03e08b9c4de8 326 Gene3D G3DSA:3.30.930.10 65 270 8.3E-61 T 29-03-2018 MC49_RS04210 78e51ff4c9e567284eaa03e08b9c4de8 326 SUPERFAMILY SSF46785 6 61 4.86E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS04210 78e51ff4c9e567284eaa03e08b9c4de8 326 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 7 317 32.642 T 29-03-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 MC49_RS04210 78e51ff4c9e567284eaa03e08b9c4de8 326 Gene3D G3DSA:1.10.10.10 1 64 5.2E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS04210 78e51ff4c9e567284eaa03e08b9c4de8 326 TIGRFAM TIGR00122 birA_repr_reg: biotin operon repressor 6 74 1.3E-23 T 29-03-2018 IPR004409 Biotin operon repressor, helix-turn-helix domain GO:0006355 KEGG: 00780+6.3.4.15 MC49_RS04210 78e51ff4c9e567284eaa03e08b9c4de8 326 SUPERFAMILY SSF50037 271 317 8.7E-9 T 29-03-2018 IPR008988 Transcriptional repressor, C-terminal MC49_RS04210 78e51ff4c9e567284eaa03e08b9c4de8 326 Gene3D G3DSA:2.30.30.100 272 318 8.6E-11 T 29-03-2018 MC49_RS04210 78e51ff4c9e567284eaa03e08b9c4de8 326 Pfam PF08279 HTH domain 12 59 1.7E-10 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 MC49_RS04210 78e51ff4c9e567284eaa03e08b9c4de8 326 Pfam PF02237 Biotin protein ligase C terminal domain 272 317 8.3E-7 T 29-03-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 MC49_RS11720 db97832edff244e2bffccb91d109a078 302 SUPERFAMILY SSF51569 10 298 1.26E-72 T 29-03-2018 MC49_RS11720 db97832edff244e2bffccb91d109a078 302 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 137 168 - T 29-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 MC49_RS11720 db97832edff244e2bffccb91d109a078 302 Pfam PF00701 Dihydrodipicolinate synthetase family 8 296 2.1E-63 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MC49_RS11720 db97832edff244e2bffccb91d109a078 302 Gene3D G3DSA:3.20.20.70 8 301 6.9E-73 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS11720 db97832edff244e2bffccb91d109a078 302 PIRSF PIRSF001365 5 302 5.1E-68 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MC49_RS11720 db97832edff244e2bffccb91d109a078 302 SMART SM01130 6 299 7.8E-74 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MC49_RS11720 db97832edff244e2bffccb91d109a078 302 PRINTS PR00146 Dihydrodipicolinate synthase signature 107 123 2.6E-13 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MC49_RS11720 db97832edff244e2bffccb91d109a078 302 PRINTS PR00146 Dihydrodipicolinate synthase signature 132 149 2.6E-13 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MC49_RS11720 db97832edff244e2bffccb91d109a078 302 PRINTS PR00146 Dihydrodipicolinate synthase signature 75 93 2.6E-13 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MC49_RS11720 db97832edff244e2bffccb91d109a078 302 PRINTS PR00146 Dihydrodipicolinate synthase signature 39 60 2.6E-13 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MC49_RS01310 d41e5d8132d413fd959158e5e4b3e64e 567 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 543 552 - T 29-03-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 MC49_RS01310 d41e5d8132d413fd959158e5e4b3e64e 567 SUPERFAMILY SSF56762 1 552 1.31E-170 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS01310 d41e5d8132d413fd959158e5e4b3e64e 567 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 39 64 - T 29-03-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 MC49_RS01310 d41e5d8132d413fd959158e5e4b3e64e 567 Gene3D G3DSA:1.10.645.10 1 552 3.5E-182 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS01310 d41e5d8132d413fd959158e5e4b3e64e 567 Pfam PF00374 Nickel-dependent hydrogenase 39 552 1.6E-206 T 29-03-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 MC49_RS18985 6845a49e2d2dc70517148fa948348b7a 328 Pfam PF04198 Putative sugar-binding domain 72 325 8.1E-71 T 29-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 MC49_RS18985 6845a49e2d2dc70517148fa948348b7a 328 Gene3D G3DSA:1.10.10.60 5 61 5.5E-14 T 29-03-2018 MC49_RS18985 6845a49e2d2dc70517148fa948348b7a 328 SUPERFAMILY SSF100950 72 325 1.3E-63 T 29-03-2018 MC49_RS18985 6845a49e2d2dc70517148fa948348b7a 328 Gene3D G3DSA:3.40.50.1360 62 326 5.7E-38 T 29-03-2018 MC49_RS18985 6845a49e2d2dc70517148fa948348b7a 328 Pfam PF13384 Homeodomain-like domain 20 59 3.8E-6 T 29-03-2018 MC49_RS18985 6845a49e2d2dc70517148fa948348b7a 328 SUPERFAMILY SSF88659 24 56 3.53E-5 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS11945 bfe8877ada753042f47fda491747de82 593 TIGRFAM TIGR03359 VI_chp_6: type VI secretion protein, TIGR03359 family 5 590 4.1E-156 T 29-03-2018 IPR010272 Type VI secretion system, TssF-like MC49_RS11945 bfe8877ada753042f47fda491747de82 593 Pfam PF05947 Type VI secretion system, TssF 6 589 1.3E-158 T 29-03-2018 IPR010272 Type VI secretion system, TssF-like MC49_RS11945 bfe8877ada753042f47fda491747de82 593 PIRSF PIRSF028304 1 593 2.4E-144 T 29-03-2018 IPR010272 Type VI secretion system, TssF-like MC49_RS05820 f3bbfbe939c0595df9723917e9704a10 395 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 6 380 7.3E-61 T 29-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 MC49_RS05820 f3bbfbe939c0595df9723917e9704a10 395 Gene3D G3DSA:1.20.1250.20 1 194 1.1E-26 T 29-03-2018 MC49_RS05820 f3bbfbe939c0595df9723917e9704a10 395 Gene3D G3DSA:1.20.1250.20 195 393 2.4E-11 T 29-03-2018 MC49_RS05820 f3bbfbe939c0595df9723917e9704a10 395 Pfam PF07690 Major Facilitator Superfamily 17 350 2.2E-36 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS05820 f3bbfbe939c0595df9723917e9704a10 395 SUPERFAMILY SSF103473 7 389 3.53E-58 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS11060 f2d06be8cae5778f3d38ad42bad2b0ed 319 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 135 155 - T 29-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 MC49_RS11060 f2d06be8cae5778f3d38ad42bad2b0ed 319 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 299 4.8E-49 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS11060 f2d06be8cae5778f3d38ad42bad2b0ed 319 Gene3D G3DSA:3.50.50.60 185 314 8.5E-13 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS11060 f2d06be8cae5778f3d38ad42bad2b0ed 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 6.1E-40 T 29-03-2018 MC49_RS11060 f2d06be8cae5778f3d38ad42bad2b0ed 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 6.1E-40 T 29-03-2018 MC49_RS11060 f2d06be8cae5778f3d38ad42bad2b0ed 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 287 6.1E-40 T 29-03-2018 MC49_RS11060 f2d06be8cae5778f3d38ad42bad2b0ed 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 6.1E-40 T 29-03-2018 MC49_RS11060 f2d06be8cae5778f3d38ad42bad2b0ed 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 235 251 6.1E-40 T 29-03-2018 MC49_RS11060 f2d06be8cae5778f3d38ad42bad2b0ed 319 Gene3D G3DSA:3.50.50.60 127 184 4.7E-10 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS11060 f2d06be8cae5778f3d38ad42bad2b0ed 319 SUPERFAMILY SSF51905 2 312 1.47E-52 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS11060 f2d06be8cae5778f3d38ad42bad2b0ed 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 3.6E-75 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MC49_RS11060 f2d06be8cae5778f3d38ad42bad2b0ed 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 128 140 3.6E-75 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MC49_RS11060 f2d06be8cae5778f3d38ad42bad2b0ed 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 237 258 3.6E-75 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MC49_RS11060 f2d06be8cae5778f3d38ad42bad2b0ed 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 3.6E-75 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MC49_RS11060 f2d06be8cae5778f3d38ad42bad2b0ed 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 106 114 3.6E-75 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MC49_RS11060 f2d06be8cae5778f3d38ad42bad2b0ed 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 275 293 3.6E-75 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MC49_RS11060 f2d06be8cae5778f3d38ad42bad2b0ed 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 198 214 3.6E-75 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MC49_RS11060 f2d06be8cae5778f3d38ad42bad2b0ed 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 3.6E-75 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MC49_RS11060 f2d06be8cae5778f3d38ad42bad2b0ed 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 143 167 3.6E-75 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MC49_RS11060 f2d06be8cae5778f3d38ad42bad2b0ed 319 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 8 312 2.7E-122 T 29-03-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 MC49_RS11060 f2d06be8cae5778f3d38ad42bad2b0ed 319 Gene3D G3DSA:3.50.50.60 1 126 8.0E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS03520 3e772bf77040de4943922ede147986f9 68 Pfam PF06526 Protein of unknown function (DUF1107) 1 62 6.4E-30 T 29-03-2018 IPR009491 Protein of unknown function DUF1107 MC49_RS03520 3e772bf77040de4943922ede147986f9 68 ProDom PD055267 YTFK Y0656 CYTOPLASMIC VP2585 VV0426 ESCHERICHIA S4534 VC2473 YPO3527 COLI 1 65 8.0E-25 T 29-03-2018 IPR009491 Protein of unknown function DUF1107 MC49_RS03520 3e772bf77040de4943922ede147986f9 68 Gene3D G3DSA:3.30.1910.10 1 61 2.2E-30 T 29-03-2018 MC49_RS06835 c89c39f7cb1e812f7e30342e5ab019c8 167 Pfam PF07278 Protein of unknown function (DUF1441) 13 161 2.8E-52 T 29-03-2018 IPR009901 Bacteriophage VT1-Sakai, H0025 MC49_RS06835 c89c39f7cb1e812f7e30342e5ab019c8 167 Gene3D G3DSA:1.10.10.10 5 162 4.8E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS08895 70e5919495b35202e9d8a8d7b0d89b1b 465 Hamap MF_00544 Tryptophanase [tnaA]. 1 464 104.82 T 29-03-2018 IPR013440 Tryptophanase GO:0006568|GO:0009034 KEGG: 00380+4.1.99.1 MC49_RS08895 70e5919495b35202e9d8a8d7b0d89b1b 465 PIRSF PIRSF001386 1 465 5.2E-226 T 29-03-2018 IPR011166 Beta-eliminating lyase family GO:0009072|GO:0016830 KEGG: 00380+4.1.99.1 MC49_RS08895 70e5919495b35202e9d8a8d7b0d89b1b 465 Gene3D G3DSA:3.40.640.10 105 258 1.3E-4 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS08895 70e5919495b35202e9d8a8d7b0d89b1b 465 Gene3D G3DSA:3.90.1150.10 17 104 1.1E-26 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS08895 70e5919495b35202e9d8a8d7b0d89b1b 465 Gene3D G3DSA:3.90.1150.10 280 462 1.1E-75 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS08895 70e5919495b35202e9d8a8d7b0d89b1b 465 Pfam PF01212 Beta-eliminating lyase 46 430 9.3E-100 T 29-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 MC49_RS08895 70e5919495b35202e9d8a8d7b0d89b1b 465 SUPERFAMILY SSF53383 2 464 1.6E-146 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS08895 70e5919495b35202e9d8a8d7b0d89b1b 465 TIGRFAM TIGR02617 tnaA_trp_ase: tryptophanase 2 464 8.9E-266 T 29-03-2018 IPR013440 Tryptophanase GO:0006568|GO:0009034 KEGG: 00380+4.1.99.1 MC49_RS08895 70e5919495b35202e9d8a8d7b0d89b1b 465 ProSitePatterns PS00853 Beta-eliminating lyases pyridoxal-phosphate attachment site. 254 272 - T 29-03-2018 IPR018176 Tryptophanase, conserved site KEGG: 00380+4.1.99.1 MC49_RS00840 dd9ec1f5ea0ad05249569f285e91ebc6 307 Pfam PF00348 Polyprenyl synthetase 42 276 8.1E-56 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 MC49_RS00840 dd9ec1f5ea0ad05249569f285e91ebc6 307 SUPERFAMILY SSF48576 11 297 4.11E-85 T 29-03-2018 IPR008949 Isoprenoid synthase domain MC49_RS00840 dd9ec1f5ea0ad05249569f285e91ebc6 307 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 89 105 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site MC49_RS00840 dd9ec1f5ea0ad05249569f285e91ebc6 307 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 223 235 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site MC49_RS00840 dd9ec1f5ea0ad05249569f285e91ebc6 307 Gene3D G3DSA:1.10.600.10 1 307 1.5E-82 T 29-03-2018 IPR008949 Isoprenoid synthase domain MC49_RS04170 b5d6d69b79857b6d33d09116d488fcea 160 PRINTS PR00601 Bacterioferritin signature 3 22 2.9E-75 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MC49_RS04170 b5d6d69b79857b6d33d09116d488fcea 160 PRINTS PR00601 Bacterioferritin signature 128 149 2.9E-75 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MC49_RS04170 b5d6d69b79857b6d33d09116d488fcea 160 PRINTS PR00601 Bacterioferritin signature 107 127 2.9E-75 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MC49_RS04170 b5d6d69b79857b6d33d09116d488fcea 160 PRINTS PR00601 Bacterioferritin signature 23 43 2.9E-75 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MC49_RS04170 b5d6d69b79857b6d33d09116d488fcea 160 PRINTS PR00601 Bacterioferritin signature 44 64 2.9E-75 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MC49_RS04170 b5d6d69b79857b6d33d09116d488fcea 160 PRINTS PR00601 Bacterioferritin signature 65 85 2.9E-75 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MC49_RS04170 b5d6d69b79857b6d33d09116d488fcea 160 PRINTS PR00601 Bacterioferritin signature 86 106 2.9E-75 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MC49_RS04170 b5d6d69b79857b6d33d09116d488fcea 160 SUPERFAMILY SSF47240 1 154 6.46E-54 T 29-03-2018 IPR009078 Ferritin-like superfamily MC49_RS04170 b5d6d69b79857b6d33d09116d488fcea 160 PIRSF PIRSF002560 1 157 1.2E-70 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MC49_RS04170 b5d6d69b79857b6d33d09116d488fcea 160 Pfam PF00210 Ferritin-like domain 8 144 6.1E-40 T 29-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 MC49_RS04170 b5d6d69b79857b6d33d09116d488fcea 160 TIGRFAM TIGR00754 bfr: bacterioferritin 1 156 3.9E-79 T 29-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MC49_RS04170 b5d6d69b79857b6d33d09116d488fcea 160 Gene3D G3DSA:1.20.1260.10 1 154 2.2E-41 T 29-03-2018 IPR012347 Ferritin-related MC49_RS03995 63a5f24f9208559a4acd53fb26fe0148 169 Hamap MF_00163 Peptide deformylase [def]. 2 162 31.079 T 29-03-2018 IPR023635 Peptide deformylase MC49_RS03995 63a5f24f9208559a4acd53fb26fe0148 169 PRINTS PR01576 Peptide deformylase signature 120 149 5.0E-37 T 29-03-2018 IPR023635 Peptide deformylase MC49_RS03995 63a5f24f9208559a4acd53fb26fe0148 169 PRINTS PR01576 Peptide deformylase signature 89 100 5.0E-37 T 29-03-2018 IPR023635 Peptide deformylase MC49_RS03995 63a5f24f9208559a4acd53fb26fe0148 169 PRINTS PR01576 Peptide deformylase signature 33 62 5.0E-37 T 29-03-2018 IPR023635 Peptide deformylase MC49_RS03995 63a5f24f9208559a4acd53fb26fe0148 169 PRINTS PR01576 Peptide deformylase signature 101 119 5.0E-37 T 29-03-2018 IPR023635 Peptide deformylase MC49_RS03995 63a5f24f9208559a4acd53fb26fe0148 169 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 160 2.8E-63 T 29-03-2018 IPR023635 Peptide deformylase MC49_RS03995 63a5f24f9208559a4acd53fb26fe0148 169 Pfam PF01327 Polypeptide deformylase 5 152 1.6E-49 T 29-03-2018 IPR023635 Peptide deformylase MC49_RS03995 63a5f24f9208559a4acd53fb26fe0148 169 PIRSF PIRSF004749 1 169 5.4E-55 T 29-03-2018 IPR023635 Peptide deformylase MC49_RS03995 63a5f24f9208559a4acd53fb26fe0148 169 Gene3D G3DSA:3.90.45.10 1 169 1.4E-59 T 29-03-2018 IPR023635 Peptide deformylase MC49_RS03995 63a5f24f9208559a4acd53fb26fe0148 169 SUPERFAMILY SSF56420 3 164 3.4E-61 T 29-03-2018 IPR023635 Peptide deformylase MC49_RS09635 c77e88eb961070b459ec93a87aef3fc1 316 SUPERFAMILY SSF52440 2 122 5.18E-45 T 29-03-2018 IPR016185 Pre-ATP-grasp domain MC49_RS09635 c77e88eb961070b459ec93a87aef3fc1 316 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 124 296 1.6E-77 T 29-03-2018 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 MC49_RS09635 c77e88eb961070b459ec93a87aef3fc1 316 Gene3D G3DSA:3.30.1490.20 138 191 7.4E-22 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MC49_RS09635 c77e88eb961070b459ec93a87aef3fc1 316 Gene3D G3DSA:3.30.470.20 192 300 6.3E-15 T 29-03-2018 MC49_RS09635 c77e88eb961070b459ec93a87aef3fc1 316 Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain 2 120 4.1E-46 T 29-03-2018 IPR004215 Prokaryotic glutathione synthetase, N-terminal GO:0004363|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 MC49_RS09635 c77e88eb961070b459ec93a87aef3fc1 316 Gene3D G3DSA:3.40.50.20 2 129 6.8E-51 T 29-03-2018 MC49_RS09635 c77e88eb961070b459ec93a87aef3fc1 316 SUPERFAMILY SSF56059 123 313 1.57E-55 T 29-03-2018 MC49_RS09635 c77e88eb961070b459ec93a87aef3fc1 316 Hamap MF_00162 Glutathione synthetase [gshB]. 1 316 176.887 T 29-03-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 MC49_RS09635 c77e88eb961070b459ec93a87aef3fc1 316 TIGRFAM TIGR01380 glut_syn: glutathione synthase 2 313 2.5E-134 T 29-03-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 MC49_RS18075 878c9820c5ba808a4d986712aca56b21 318 Gene3D G3DSA:3.40.50.1820 29 318 1.8E-46 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS18075 878c9820c5ba808a4d986712aca56b21 318 Pfam PF00561 alpha/beta hydrolase fold 63 171 3.4E-14 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MC49_RS18075 878c9820c5ba808a4d986712aca56b21 318 PRINTS PR00412 Epoxide hydrolase signature 68 86 1.2E-12 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MC49_RS18075 878c9820c5ba808a4d986712aca56b21 318 PRINTS PR00412 Epoxide hydrolase signature 293 315 1.2E-12 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MC49_RS18075 878c9820c5ba808a4d986712aca56b21 318 PRINTS PR00412 Epoxide hydrolase signature 88 103 1.2E-12 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MC49_RS18075 878c9820c5ba808a4d986712aca56b21 318 PRINTS PR00412 Epoxide hydrolase signature 132 145 1.2E-12 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MC49_RS18075 878c9820c5ba808a4d986712aca56b21 318 SUPERFAMILY SSF53474 31 317 8.66E-66 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS07730 32144e2ae45829e8d6a4ad532e0efce2 212 Gene3D G3DSA:3.90.79.10 3 210 1.7E-40 T 29-03-2018 MC49_RS07730 32144e2ae45829e8d6a4ad532e0efce2 212 Pfam PF00293 NUDIX domain 58 180 2.4E-9 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MC49_RS07730 32144e2ae45829e8d6a4ad532e0efce2 212 SUPERFAMILY SSF55811 4 206 2.3E-47 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MC49_RS07730 32144e2ae45829e8d6a4ad532e0efce2 212 TIGRFAM TIGR00052 TIGR00052: nudix-type nucleoside diphosphatase, YffH/AdpP family 15 200 4.6E-64 T 29-03-2018 IPR004385 Nucleoside diphosphate pyrophosphatase GO:0016818|GO:0046872 Reactome: R-HSA-480985 MC49_RS03420 96f6ff4e4c28789a6f03ab832b2760b7 209 Pfam PF01728 FtsJ-like methyltransferase 31 206 1.0E-57 T 29-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 MC49_RS03420 96f6ff4e4c28789a6f03ab832b2760b7 209 PIRSF PIRSF005461 1 209 5.1E-80 T 29-03-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 MC49_RS03420 96f6ff4e4c28789a6f03ab832b2760b7 209 Gene3D G3DSA:3.40.50.150 1 209 9.8E-58 T 29-03-2018 MC49_RS03420 96f6ff4e4c28789a6f03ab832b2760b7 209 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 15 208 27.994 T 29-03-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 MC49_RS03420 96f6ff4e4c28789a6f03ab832b2760b7 209 SUPERFAMILY SSF53335 31 207 3.75E-43 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS03420 96f6ff4e4c28789a6f03ab832b2760b7 209 TIGRFAM TIGR00438 rrmJ: ribosomal RNA large subunit methyltransferase J 20 206 9.3E-93 T 29-03-2018 IPR004512 Ribosomal RNA methyltransferase E, gammaproteobacteria GO:0006364|GO:0016436 KEGG: 00564+2.1.1.16 MC49_RS14815 424946dde3b8ea3b0dadefb6de04e975 278 Gene3D G3DSA:2.60.120.280 9 190 7.3E-12 T 29-03-2018 MC49_RS14815 424946dde3b8ea3b0dadefb6de04e975 278 Pfam PF02311 AraC-like ligand binding domain 24 153 1.4E-25 T 29-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 MC49_RS14815 424946dde3b8ea3b0dadefb6de04e975 278 SMART SM00342 193 275 3.1E-30 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MC49_RS14815 424946dde3b8ea3b0dadefb6de04e975 278 Pfam PF12833 Helix-turn-helix domain 199 277 1.0E-22 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MC49_RS14815 424946dde3b8ea3b0dadefb6de04e975 278 Gene3D G3DSA:1.10.10.60 232 278 1.2E-14 T 29-03-2018 MC49_RS14815 424946dde3b8ea3b0dadefb6de04e975 278 Gene3D G3DSA:1.10.10.60 191 231 1.8E-14 T 29-03-2018 MC49_RS14815 424946dde3b8ea3b0dadefb6de04e975 278 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 259 275 3.9E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MC49_RS14815 424946dde3b8ea3b0dadefb6de04e975 278 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 244 259 3.9E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MC49_RS14815 424946dde3b8ea3b0dadefb6de04e975 278 SUPERFAMILY SSF46689 230 277 2.87E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS14815 424946dde3b8ea3b0dadefb6de04e975 278 SUPERFAMILY SSF51215 32 159 2.75E-20 T 29-03-2018 MC49_RS14815 424946dde3b8ea3b0dadefb6de04e975 278 SUPERFAMILY SSF46689 177 227 3.29E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS12635 c2f50cd67ed6c5c0d2e0ab1739365999 330 Gene3D G3DSA:1.10.220.30 67 189 1.9E-21 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical MC49_RS12635 c2f50cd67ed6c5c0d2e0ab1739365999 330 Gene3D G3DSA:1.10.220.30 193 329 2.1E-29 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical MC49_RS12635 c2f50cd67ed6c5c0d2e0ab1739365999 330 Pfam PF14841 FliG middle domain 114 186 8.6E-25 T 29-03-2018 IPR032779 Flagellar motor switch protein FliG, middle domain MC49_RS12635 c2f50cd67ed6c5c0d2e0ab1739365999 330 Gene3D G3DSA:1.10.220.30 1 66 5.2E-10 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical MC49_RS12635 c2f50cd67ed6c5c0d2e0ab1739365999 330 SUPERFAMILY SSF48029 4 102 7.06E-21 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical MC49_RS12635 c2f50cd67ed6c5c0d2e0ab1739365999 330 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 2 330 1.4E-130 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 MC49_RS12635 c2f50cd67ed6c5c0d2e0ab1739365999 330 SUPERFAMILY SSF48029 113 323 2.75E-63 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical MC49_RS12635 c2f50cd67ed6c5c0d2e0ab1739365999 330 Pfam PF14842 FliG N-terminal domain 2 101 1.8E-29 T 29-03-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain MC49_RS12635 c2f50cd67ed6c5c0d2e0ab1739365999 330 PRINTS PR00954 Flagellar motor switch protein FliG signature 3 19 1.7E-68 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 MC49_RS12635 c2f50cd67ed6c5c0d2e0ab1739365999 330 PRINTS PR00954 Flagellar motor switch protein FliG signature 224 244 1.7E-68 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 MC49_RS12635 c2f50cd67ed6c5c0d2e0ab1739365999 330 PRINTS PR00954 Flagellar motor switch protein FliG signature 270 296 1.7E-68 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 MC49_RS12635 c2f50cd67ed6c5c0d2e0ab1739365999 330 PRINTS PR00954 Flagellar motor switch protein FliG signature 193 218 1.7E-68 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 MC49_RS12635 c2f50cd67ed6c5c0d2e0ab1739365999 330 PRINTS PR00954 Flagellar motor switch protein FliG signature 246 266 1.7E-68 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 MC49_RS12635 c2f50cd67ed6c5c0d2e0ab1739365999 330 PRINTS PR00954 Flagellar motor switch protein FliG signature 113 136 1.7E-68 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 MC49_RS12635 c2f50cd67ed6c5c0d2e0ab1739365999 330 PRINTS PR00954 Flagellar motor switch protein FliG signature 32 58 1.7E-68 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 MC49_RS12635 c2f50cd67ed6c5c0d2e0ab1739365999 330 Pfam PF01706 FliG C-terminal domain 217 322 4.6E-37 T 29-03-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal MC49_RS12635 c2f50cd67ed6c5c0d2e0ab1739365999 330 PIRSF PIRSF003161 1 330 1.7E-111 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 MC49_RS06005 4f9e99c4e22e3c08b301ad1b3d41e69f 349 SUPERFAMILY SSF55785 9 100 1.68E-6 T 29-03-2018 IPR000014 PAS domain MC49_RS06005 4f9e99c4e22e3c08b301ad1b3d41e69f 349 Pfam PF08448 PAS fold 13 70 3.1E-5 T 29-03-2018 IPR013656 PAS fold-4 MC49_RS06005 4f9e99c4e22e3c08b301ad1b3d41e69f 349 SMART SM00387 233 349 1.2E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS06005 4f9e99c4e22e3c08b301ad1b3d41e69f 349 Pfam PF00512 His Kinase A (phospho-acceptor) domain 131 186 3.1E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS06005 4f9e99c4e22e3c08b301ad1b3d41e69f 349 SMART SM00388 129 194 1.1E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS06005 4f9e99c4e22e3c08b301ad1b3d41e69f 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 310 328 1.2E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS06005 4f9e99c4e22e3c08b301ad1b3d41e69f 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 333 346 1.2E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS06005 4f9e99c4e22e3c08b301ad1b3d41e69f 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 281 295 1.2E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS06005 4f9e99c4e22e3c08b301ad1b3d41e69f 349 Gene3D G3DSA:3.30.450.20 7 129 1.2E-9 T 29-03-2018 MC49_RS06005 4f9e99c4e22e3c08b301ad1b3d41e69f 349 SUPERFAMILY SSF55874 198 346 2.36E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS06005 4f9e99c4e22e3c08b301ad1b3d41e69f 349 Gene3D G3DSA:3.30.565.10 191 349 5.0E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS06005 4f9e99c4e22e3c08b301ad1b3d41e69f 349 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 235 347 8.0E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS06005 4f9e99c4e22e3c08b301ad1b3d41e69f 349 SUPERFAMILY SSF47384 120 187 2.75E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS06005 4f9e99c4e22e3c08b301ad1b3d41e69f 349 SMART SM00091 7 75 1.5E-4 T 29-03-2018 IPR000014 PAS domain MC49_RS06005 4f9e99c4e22e3c08b301ad1b3d41e69f 349 Gene3D G3DSA:1.10.287.130 130 187 2.9E-15 T 29-03-2018 MC49_RS11535 5f206cb3573b3f1a118dd92159ddee97 305 SUPERFAMILY SSF53850 105 288 2.44E-21 T 29-03-2018 MC49_RS11535 5f206cb3573b3f1a118dd92159ddee97 305 SUPERFAMILY SSF46785 1 86 1.27E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS11535 5f206cb3573b3f1a118dd92159ddee97 305 Gene3D G3DSA:3.40.190.10 92 177 2.2E-7 T 29-03-2018 MC49_RS11535 5f206cb3573b3f1a118dd92159ddee97 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.6E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS11535 5f206cb3573b3f1a118dd92159ddee97 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.6E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS11535 5f206cb3573b3f1a118dd92159ddee97 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.6E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS11535 5f206cb3573b3f1a118dd92159ddee97 305 Pfam PF03466 LysR substrate binding domain 104 277 1.4E-22 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS11535 5f206cb3573b3f1a118dd92159ddee97 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 7.5E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS11535 5f206cb3573b3f1a118dd92159ddee97 305 Gene3D G3DSA:1.10.10.10 1 87 1.4E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS11535 5f206cb3573b3f1a118dd92159ddee97 305 Gene3D G3DSA:3.40.190.10 178 266 4.4E-15 T 29-03-2018 MC49_RS03985 e511f2eb06b418b00e7c77ebf9a9e3d3 181 SUPERFAMILY SSF57783 55 92 1.24E-12 T 29-03-2018 MC49_RS03985 e511f2eb06b418b00e7c77ebf9a9e3d3 181 SUPERFAMILY SSF57783 8 42 2.98E-12 T 29-03-2018 MC49_RS03985 e511f2eb06b418b00e7c77ebf9a9e3d3 181 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 7 43 1.2E-14 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 MC49_RS03985 e511f2eb06b418b00e7c77ebf9a9e3d3 181 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 99 136 9.6E-13 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 MC49_RS03985 e511f2eb06b418b00e7c77ebf9a9e3d3 181 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 56 91 3.0E-17 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 MC49_RS03985 e511f2eb06b418b00e7c77ebf9a9e3d3 181 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 139 163 1.4 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 MC49_RS03985 e511f2eb06b418b00e7c77ebf9a9e3d3 181 Gene3D G3DSA:3.30.65.10 1 49 1.5E-16 T 29-03-2018 MC49_RS03985 e511f2eb06b418b00e7c77ebf9a9e3d3 181 Gene3D G3DSA:3.30.65.10 93 140 7.6E-12 T 29-03-2018 MC49_RS03985 e511f2eb06b418b00e7c77ebf9a9e3d3 181 Gene3D G3DSA:3.30.65.10 50 92 3.4E-15 T 29-03-2018 MC49_RS02155 687f3171e99b88e0fedbac7a30b9045b 320 SUPERFAMILY SSF56349 4 312 1.47E-33 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MC49_RS02155 687f3171e99b88e0fedbac7a30b9045b 320 Gene3D G3DSA:1.10.150.130 1 108 6.1E-15 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal MC49_RS02155 687f3171e99b88e0fedbac7a30b9045b 320 Pfam PF13102 Phage integrase SAM-like domain 15 94 1.4E-6 T 29-03-2018 IPR025269 Phage integrase SAM-like domain MC49_RS02155 687f3171e99b88e0fedbac7a30b9045b 320 Gene3D G3DSA:1.10.443.10 109 316 1.3E-23 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MC49_RS02155 687f3171e99b88e0fedbac7a30b9045b 320 Pfam PF00589 Phage integrase family 154 305 7.2E-17 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MC49_RS14870 e0e04ab3a5850173cd2f16876c190b49 161 SUPERFAMILY SSF55729 1 143 1.22E-18 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS14870 e0e04ab3a5850173cd2f16876c190b49 161 Pfam PF00583 Acetyltransferase (GNAT) family 31 138 4.9E-8 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MC49_RS14870 e0e04ab3a5850173cd2f16876c190b49 161 Gene3D G3DSA:3.40.630.30 1 147 1.3E-18 T 29-03-2018 MC49_RS15085 b847d09c054a045cf84dcb86a3e5860d 244 Pfam PF01569 PAP2 superfamily 80 233 3.8E-27 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MC49_RS15085 b847d09c054a045cf84dcb86a3e5860d 244 SMART SM00014 75 227 1.9E-22 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MC49_RS15085 b847d09c054a045cf84dcb86a3e5860d 244 SUPERFAMILY SSF48317 145 233 7.72E-27 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MC49_RS15085 b847d09c054a045cf84dcb86a3e5860d 244 SUPERFAMILY SSF48317 14 113 7.72E-27 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MC49_RS15085 b847d09c054a045cf84dcb86a3e5860d 244 Gene3D G3DSA:1.20.144.10 10 237 4.0E-25 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MC49_RS11725 9ee3eb1327162969785a67a7e56d1118 428 Gene3D G3DSA:1.20.1250.20 11 221 2.0E-35 T 29-03-2018 MC49_RS11725 9ee3eb1327162969785a67a7e56d1118 428 Pfam PF07690 Major Facilitator Superfamily 27 388 8.8E-40 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS11725 9ee3eb1327162969785a67a7e56d1118 428 Gene3D G3DSA:1.20.1250.20 234 428 3.7E-17 T 29-03-2018 MC49_RS11725 9ee3eb1327162969785a67a7e56d1118 428 SUPERFAMILY SSF103473 15 427 2.88E-74 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS16070 0007d0459eb44c4204099b6455f0e2d0 125 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 9 120 3.7E-33 T 29-03-2018 IPR006504 Transcriptional regulator Spx/MgsR MC49_RS16070 0007d0459eb44c4204099b6455f0e2d0 125 Gene3D G3DSA:3.40.30.10 7 122 4.0E-36 T 29-03-2018 MC49_RS16070 0007d0459eb44c4204099b6455f0e2d0 125 SUPERFAMILY SSF52833 9 121 5.52E-30 T 29-03-2018 IPR012336 Thioredoxin-like fold MC49_RS16070 0007d0459eb44c4204099b6455f0e2d0 125 Pfam PF03960 ArsC family 15 120 2.6E-17 T 29-03-2018 IPR006660 Arsenate reductase-like MC49_RS17885 dde5f25910541dd028cccc32abd6d1c6 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 4.9E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS17885 dde5f25910541dd028cccc32abd6d1c6 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 4.9E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS17885 dde5f25910541dd028cccc32abd6d1c6 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 4.9E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS17885 dde5f25910541dd028cccc32abd6d1c6 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 240 8.2E-64 T 29-03-2018 MC49_RS17885 dde5f25910541dd028cccc32abd6d1c6 251 SUPERFAMILY SSF51735 6 242 1.48E-76 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS17885 dde5f25910541dd028cccc32abd6d1c6 251 Gene3D G3DSA:3.40.50.720 6 250 2.8E-70 T 29-03-2018 MC49_RS17885 dde5f25910541dd028cccc32abd6d1c6 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.8E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS17885 dde5f25910541dd028cccc32abd6d1c6 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 2.8E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS17885 dde5f25910541dd028cccc32abd6d1c6 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 2.8E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS17885 dde5f25910541dd028cccc32abd6d1c6 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 2.8E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS17885 dde5f25910541dd028cccc32abd6d1c6 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 2.8E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS17885 dde5f25910541dd028cccc32abd6d1c6 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 2.8E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS01290 fa1f733d656776c04a2a2fb84a84b8f1 291 SUPERFAMILY SSF46785 2 86 1.22E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS01290 fa1f733d656776c04a2a2fb84a84b8f1 291 SUPERFAMILY SSF53850 83 289 1.54E-32 T 29-03-2018 MC49_RS01290 fa1f733d656776c04a2a2fb84a84b8f1 291 Gene3D G3DSA:3.40.190.10 178 259 7.6E-18 T 29-03-2018 MC49_RS01290 fa1f733d656776c04a2a2fb84a84b8f1 291 Gene3D G3DSA:3.40.190.10 94 177 1.5E-12 T 29-03-2018 MC49_RS01290 fa1f733d656776c04a2a2fb84a84b8f1 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 2.5E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS01290 fa1f733d656776c04a2a2fb84a84b8f1 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 2.5E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS01290 fa1f733d656776c04a2a2fb84a84b8f1 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 2.5E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS01290 fa1f733d656776c04a2a2fb84a84b8f1 291 Pfam PF03466 LysR substrate binding domain 90 288 1.7E-36 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS01290 fa1f733d656776c04a2a2fb84a84b8f1 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 1.3E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS01290 fa1f733d656776c04a2a2fb84a84b8f1 291 Gene3D G3DSA:1.10.10.10 2 90 3.2E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS08370 c0cd7ba845b8104891252798e2a95970 181 Gene3D G3DSA:3.40.50.300 1 181 1.5E-56 T 29-03-2018 MC49_RS08370 c0cd7ba845b8104891252798e2a95970 181 PIRSF PIRSF006135 1 181 3.1E-53 T 29-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 MC49_RS08370 c0cd7ba845b8104891252798e2a95970 181 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 2 180 5.8E-56 T 29-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 MC49_RS08370 c0cd7ba845b8104891252798e2a95970 181 SUPERFAMILY SSF52540 1 181 4.96E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS03540 98f184a14123a422ecf4b8246600280c 149 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS03540 98f184a14123a422ecf4b8246600280c 149 Gene3D G3DSA:3.10.430.100 63 148 1.6E-24 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal MC49_RS03540 98f184a14123a422ecf4b8246600280c 149 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 149 25.6 T 29-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS03540 98f184a14123a422ecf4b8246600280c 149 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 148 8.7E-25 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal MC49_RS03540 98f184a14123a422ecf4b8246600280c 149 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 149 1.6E-57 T 29-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS03540 98f184a14123a422ecf4b8246600280c 149 SUPERFAMILY SSF55658 1 57 2.09E-19 T 29-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal MC49_RS03540 98f184a14123a422ecf4b8246600280c 149 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 45 3.6E-22 T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS03540 98f184a14123a422ecf4b8246600280c 149 Gene3D G3DSA:3.40.5.10 1 49 6.9E-23 T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS03540 98f184a14123a422ecf4b8246600280c 149 SUPERFAMILY SSF55653 60 149 1.83E-24 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal MC49_RS15780 089a1fa75206f75ee972e804d66d2871 470 Gene3D G3DSA:3.20.20.60 1 81 5.8E-19 T 29-03-2018 MC49_RS15780 089a1fa75206f75ee972e804d66d2871 470 PRINTS PR01050 Pyruvate kinase family signature 59 75 1.3E-77 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MC49_RS15780 089a1fa75206f75ee972e804d66d2871 470 PRINTS PR01050 Pyruvate kinase family signature 244 268 1.3E-77 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MC49_RS15780 089a1fa75206f75ee972e804d66d2871 470 PRINTS PR01050 Pyruvate kinase family signature 294 312 1.3E-77 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MC49_RS15780 089a1fa75206f75ee972e804d66d2871 470 PRINTS PR01050 Pyruvate kinase family signature 186 200 1.3E-77 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MC49_RS15780 089a1fa75206f75ee972e804d66d2871 470 PRINTS PR01050 Pyruvate kinase family signature 217 243 1.3E-77 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MC49_RS15780 089a1fa75206f75ee972e804d66d2871 470 PRINTS PR01050 Pyruvate kinase family signature 313 329 1.3E-77 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MC49_RS15780 089a1fa75206f75ee972e804d66d2871 470 PRINTS PR01050 Pyruvate kinase family signature 269 293 1.3E-77 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MC49_RS15780 089a1fa75206f75ee972e804d66d2871 470 SUPERFAMILY SSF50800 70 167 4.71E-29 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain MC49_RS15780 089a1fa75206f75ee972e804d66d2871 470 Gene3D G3DSA:3.20.20.60 167 321 4.9E-63 T 29-03-2018 MC49_RS15780 089a1fa75206f75ee972e804d66d2871 470 Gene3D G3DSA:3.40.1380.20 322 469 9.2E-43 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MC49_RS15780 089a1fa75206f75ee972e804d66d2871 470 SUPERFAMILY SSF51621 1 74 2.09E-100 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MC49_RS15780 089a1fa75206f75ee972e804d66d2871 470 SUPERFAMILY SSF51621 156 339 2.09E-100 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MC49_RS15780 089a1fa75206f75ee972e804d66d2871 470 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 468 7.2E-185 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MC49_RS15780 089a1fa75206f75ee972e804d66d2871 470 ProSitePatterns PS00110 Pyruvate kinase active site signature. 215 227 - T 29-03-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MC49_RS15780 089a1fa75206f75ee972e804d66d2871 470 Pfam PF02887 Pyruvate kinase, alpha/beta domain 356 467 5.5E-27 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MC49_RS15780 089a1fa75206f75ee972e804d66d2871 470 Gene3D G3DSA:2.40.33.10 82 166 5.6E-30 T 29-03-2018 MC49_RS15780 089a1fa75206f75ee972e804d66d2871 470 SUPERFAMILY SSF52935 323 468 4.97E-34 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MC49_RS15780 089a1fa75206f75ee972e804d66d2871 470 Pfam PF00224 Pyruvate kinase, barrel domain 1 341 3.9E-151 T 29-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MC49_RS03845 766dc7f0e3316c0a4467e7ef6e2d3d69 108 PRINTS PR00421 Thioredoxin family signature 24 32 3.8E-10 T 29-03-2018 MC49_RS03845 766dc7f0e3316c0a4467e7ef6e2d3d69 108 PRINTS PR00421 Thioredoxin family signature 72 83 3.8E-10 T 29-03-2018 MC49_RS03845 766dc7f0e3316c0a4467e7ef6e2d3d69 108 PRINTS PR00421 Thioredoxin family signature 32 41 3.8E-10 T 29-03-2018 MC49_RS03845 766dc7f0e3316c0a4467e7ef6e2d3d69 108 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MC49_RS03845 766dc7f0e3316c0a4467e7ef6e2d3d69 108 Gene3D G3DSA:3.40.30.10 5 72 1.7E-29 T 29-03-2018 MC49_RS03845 766dc7f0e3316c0a4467e7ef6e2d3d69 108 SUPERFAMILY SSF52833 2 107 5.31E-40 T 29-03-2018 IPR012336 Thioredoxin-like fold MC49_RS03845 766dc7f0e3316c0a4467e7ef6e2d3d69 108 PIRSF PIRSF000077 2 108 4.7E-45 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 MC49_RS03845 766dc7f0e3316c0a4467e7ef6e2d3d69 108 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 107 8.4E-40 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 MC49_RS03845 766dc7f0e3316c0a4467e7ef6e2d3d69 108 Pfam PF00085 Thioredoxin 5 106 1.7E-34 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 MC49_RS03845 766dc7f0e3316c0a4467e7ef6e2d3d69 108 Gene3D G3DSA:3.40.30.10 73 107 4.0E-6 T 29-03-2018 MC49_RS04705 9efb5399ccc3a7dcfcbc13c0c9b79321 174 PRINTS PR01100 Shikimate kinase family signature 77 86 1.8E-28 T 29-03-2018 MC49_RS04705 9efb5399ccc3a7dcfcbc13c0c9b79321 174 PRINTS PR01100 Shikimate kinase family signature 59 67 1.8E-28 T 29-03-2018 MC49_RS04705 9efb5399ccc3a7dcfcbc13c0c9b79321 174 PRINTS PR01100 Shikimate kinase family signature 7 22 1.8E-28 T 29-03-2018 MC49_RS04705 9efb5399ccc3a7dcfcbc13c0c9b79321 174 PRINTS PR01100 Shikimate kinase family signature 98 115 1.8E-28 T 29-03-2018 MC49_RS04705 9efb5399ccc3a7dcfcbc13c0c9b79321 174 PRINTS PR01100 Shikimate kinase family signature 31 44 1.8E-28 T 29-03-2018 MC49_RS04705 9efb5399ccc3a7dcfcbc13c0c9b79321 174 SUPERFAMILY SSF52540 4 170 6.51E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS04705 9efb5399ccc3a7dcfcbc13c0c9b79321 174 ProSitePatterns PS01128 Shikimate kinase signature. 60 85 - T 29-03-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 MC49_RS04705 9efb5399ccc3a7dcfcbc13c0c9b79321 174 Hamap MF_00109 Shikimate kinase [aroK]. 4 171 28.714 T 29-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 MC49_RS04705 9efb5399ccc3a7dcfcbc13c0c9b79321 174 Pfam PF01202 Shikimate kinase 13 170 2.1E-55 T 29-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 MC49_RS04705 9efb5399ccc3a7dcfcbc13c0c9b79321 174 Gene3D G3DSA:3.40.50.300 1 173 8.9E-36 T 29-03-2018 MC49_RS12245 34d8475af23eaca226ed702c4f8ceef6 343 Pfam PF13531 Bacterial extracellular solute-binding protein 44 292 3.1E-38 T 29-03-2018 MC49_RS12245 34d8475af23eaca226ed702c4f8ceef6 343 Gene3D G3DSA:3.40.190.10 30 138 3.9E-16 T 29-03-2018 MC49_RS12245 34d8475af23eaca226ed702c4f8ceef6 343 SUPERFAMILY SSF53850 31 338 1.71E-72 T 29-03-2018 MC49_RS12245 34d8475af23eaca226ed702c4f8ceef6 343 Gene3D G3DSA:3.40.190.10 139 341 4.1E-36 T 29-03-2018 MC49_RS12245 34d8475af23eaca226ed702c4f8ceef6 343 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 29 338 1.5E-140 T 29-03-2018 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 MC49_RS16460 1da067e6d4d63278135f5b4b56393f7b 443 Gene3D G3DSA:3.60.120.10 6 441 3.0E-81 T 29-03-2018 IPR005801 ADC synthase GO:0009058 MC49_RS16460 1da067e6d4d63278135f5b4b56393f7b 443 Hamap MF_01935 Isochorismate synthase MenF [menF]. 3 440 29.307 T 29-03-2018 IPR034681 Isochorismate synthase MenF GO:0008909|GO:0009234 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 MC49_RS16460 1da067e6d4d63278135f5b4b56393f7b 443 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 105 437 3.9E-90 T 29-03-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 MC49_RS16460 1da067e6d4d63278135f5b4b56393f7b 443 Pfam PF00425 chorismate binding enzyme 179 430 2.7E-57 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal MC49_RS16460 1da067e6d4d63278135f5b4b56393f7b 443 SUPERFAMILY SSF56322 39 438 1.16E-85 T 29-03-2018 IPR005801 ADC synthase GO:0009058 MC49_RS15535 04e539a45e63c23bf216e76f62002565 122 Gene3D G3DSA:1.20.120.600 14 122 9.2E-41 T 29-03-2018 MC49_RS08600 241e6e2872818477cf71cc6e4272b172 472 Pfam PF06277 Ethanolamine utilisation protein EutA 5 470 1.8E-176 T 29-03-2018 IPR009377 Ethanolamine utilisation EutA MC49_RS08600 241e6e2872818477cf71cc6e4272b172 472 Gene3D G3DSA:3.30.420.40 6 181 2.4E-9 T 29-03-2018 MC49_RS08600 241e6e2872818477cf71cc6e4272b172 472 PIRSF PIRSF012293 2 472 2.2E-191 T 29-03-2018 IPR009377 Ethanolamine utilisation EutA MC49_RS08600 241e6e2872818477cf71cc6e4272b172 472 SUPERFAMILY SSF53067 8 182 1.82E-5 T 29-03-2018 MC49_RS15305 a275f303c038e13513382789012e3910 522 Gene3D G3DSA:3.40.190.10 193 292 4.5E-16 T 29-03-2018 MC49_RS15305 a275f303c038e13513382789012e3910 522 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 75 439 1.4E-62 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain MC49_RS15305 a275f303c038e13513382789012e3910 522 Gene3D G3DSA:3.10.105.10 293 493 6.9E-37 T 29-03-2018 MC49_RS15305 a275f303c038e13513382789012e3910 522 SUPERFAMILY SSF53850 22 518 7.96E-90 T 29-03-2018 MC49_RS15305 a275f303c038e13513382789012e3910 522 Gene3D G3DSA:3.90.76.10 36 188 2.6E-18 T 29-03-2018 MC49_RS15305 a275f303c038e13513382789012e3910 522 PIRSF PIRSF002741 11 519 6.3E-61 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MC49_RS17030 4ed519735aef0d2f540e4fa5214e0b1e 434 SUPERFAMILY SSF51905 5 224 8.87E-30 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS17030 4ed519735aef0d2f540e4fa5214e0b1e 434 Gene3D G3DSA:3.50.50.60 1 142 1.7E-13 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS17030 4ed519735aef0d2f540e4fa5214e0b1e 434 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 338 1.1E-62 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS17030 4ed519735aef0d2f540e4fa5214e0b1e 434 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 1.8E-7 T 29-03-2018 MC49_RS17030 4ed519735aef0d2f540e4fa5214e0b1e 434 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 310 317 1.8E-7 T 29-03-2018 MC49_RS17030 4ed519735aef0d2f540e4fa5214e0b1e 434 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 172 197 1.8E-7 T 29-03-2018 MC49_RS17030 4ed519735aef0d2f540e4fa5214e0b1e 434 SUPERFAMILY SSF51905 169 352 1.59E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS17030 4ed519735aef0d2f540e4fa5214e0b1e 434 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 115 133 1.1E-13 T 29-03-2018 MC49_RS17030 4ed519735aef0d2f540e4fa5214e0b1e 434 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 295 317 1.1E-13 T 29-03-2018 MC49_RS17030 4ed519735aef0d2f540e4fa5214e0b1e 434 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 172 190 1.1E-13 T 29-03-2018 MC49_RS17030 4ed519735aef0d2f540e4fa5214e0b1e 434 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.1E-13 T 29-03-2018 MC49_RS17030 4ed519735aef0d2f540e4fa5214e0b1e 434 Gene3D G3DSA:3.50.50.60 143 348 1.5E-31 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS09260 8e95021856fe7502abc97e0ea113019a 358 Pfam PF01116 Fructose-bisphosphate aldolase class-II 17 356 3.8E-92 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MC49_RS09260 8e95021856fe7502abc97e0ea113019a 358 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 171 182 - T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MC49_RS09260 8e95021856fe7502abc97e0ea113019a 358 Gene3D G3DSA:3.20.20.70 4 358 4.4E-104 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS09260 8e95021856fe7502abc97e0ea113019a 358 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 99 111 - T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MC49_RS09260 8e95021856fe7502abc97e0ea113019a 358 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 14 357 2.7E-115 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MC49_RS09260 8e95021856fe7502abc97e0ea113019a 358 TIGRFAM TIGR01520 FruBisAldo_II_A: fructose-bisphosphate aldolase, class II 4 357 2.8E-186 T 29-03-2018 IPR006411 Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 MC49_RS09260 8e95021856fe7502abc97e0ea113019a 358 SUPERFAMILY SSF51569 4 356 1.3E-133 T 29-03-2018 MC49_RS09260 8e95021856fe7502abc97e0ea113019a 358 PIRSF PIRSF001359 13 358 5.6E-102 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MC49_RS07280 b520b8656ad4f6d3f4e06bd2966fc707 136 Pfam PF03603 DNA polymerase III psi subunit 1 126 1.5E-42 T 29-03-2018 IPR004615 DNA polymerase III, psi subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS07280 b520b8656ad4f6d3f4e06bd2966fc707 136 Gene3D G3DSA:3.40.50.10220 34 128 1.1E-26 T 29-03-2018 IPR004615 DNA polymerase III, psi subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS07280 b520b8656ad4f6d3f4e06bd2966fc707 136 ProDom PD032475 DNA POLYMERASE PSI SUBUNIT III TRANSFERASE NUCLEOTIDYLTRANSFERASE III 3D-STRUCTURE DNA-DIRECTED 33 128 2.0E-17 T 29-03-2018 IPR004615 DNA polymerase III, psi subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS07280 b520b8656ad4f6d3f4e06bd2966fc707 136 SUPERFAMILY SSF102220 27 130 2.88E-26 T 29-03-2018 IPR004615 DNA polymerase III, psi subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS07280 b520b8656ad4f6d3f4e06bd2966fc707 136 PIRSF PIRSF029225 1 130 3.7E-40 T 29-03-2018 IPR004615 DNA polymerase III, psi subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS10485 94dc963b852d4d7588e99ee0a3e0a4ad 292 SUPERFAMILY SSF81301 1 136 1.29E-24 T 29-03-2018 MC49_RS10485 94dc963b852d4d7588e99ee0a3e0a4ad 292 Pfam PF04439 Streptomycin adenylyltransferase 1 277 4.5E-62 T 29-03-2018 IPR007530 Aminoglycoside 6-adenylyltransferase MC49_RS10485 94dc963b852d4d7588e99ee0a3e0a4ad 292 Gene3D G3DSA:3.30.460.10 3 143 2.3E-22 T 29-03-2018 MC49_RS10485 94dc963b852d4d7588e99ee0a3e0a4ad 292 SUPERFAMILY SSF81631 144 280 5.89E-27 T 29-03-2018 MC49_RS10485 94dc963b852d4d7588e99ee0a3e0a4ad 292 Gene3D G3DSA:1.20.120.330 148 281 3.1E-19 T 29-03-2018 MC49_RS08095 102e8e832e1f7383c661dad1edcfbe0c 384 Hamap MF_00392 Lipid-A-disaccharide synthase [lpxB]. 7 383 43.323 T 29-03-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 MC49_RS08095 102e8e832e1f7383c661dad1edcfbe0c 384 Pfam PF02684 Lipid-A-disaccharide synthetase 10 378 1.0E-144 T 29-03-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 MC49_RS08095 102e8e832e1f7383c661dad1edcfbe0c 384 Gene3D G3DSA:3.40.50.2000 3 183 2.6E-5 T 29-03-2018 MC49_RS08095 102e8e832e1f7383c661dad1edcfbe0c 384 SUPERFAMILY SSF53756 10 360 1.19E-29 T 29-03-2018 MC49_RS08095 102e8e832e1f7383c661dad1edcfbe0c 384 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 6 379 2.1E-170 T 29-03-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 MC49_RS08095 102e8e832e1f7383c661dad1edcfbe0c 384 Gene3D G3DSA:3.40.50.2000 184 368 5.9E-15 T 29-03-2018 MC49_RS12550 5ef9b0ec1887d60e8beec9bc4a53b826 368 Hamap MF_00416 Flagellar P-ring protein [flgI]. 4 368 37.772 T 29-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 MC49_RS12550 5ef9b0ec1887d60e8beec9bc4a53b826 368 Pfam PF02119 Flagellar P-ring protein 24 367 3.0E-135 T 29-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 MC49_RS12550 5ef9b0ec1887d60e8beec9bc4a53b826 368 PRINTS PR01010 Flagellar P-ring protein signature 190 208 9.9E-88 T 29-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 MC49_RS12550 5ef9b0ec1887d60e8beec9bc4a53b826 368 PRINTS PR01010 Flagellar P-ring protein signature 164 182 9.9E-88 T 29-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 MC49_RS12550 5ef9b0ec1887d60e8beec9bc4a53b826 368 PRINTS PR01010 Flagellar P-ring protein signature 254 266 9.9E-88 T 29-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 MC49_RS12550 5ef9b0ec1887d60e8beec9bc4a53b826 368 PRINTS PR01010 Flagellar P-ring protein signature 59 74 9.9E-88 T 29-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 MC49_RS12550 5ef9b0ec1887d60e8beec9bc4a53b826 368 PRINTS PR01010 Flagellar P-ring protein signature 39 54 9.9E-88 T 29-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 MC49_RS12550 5ef9b0ec1887d60e8beec9bc4a53b826 368 PRINTS PR01010 Flagellar P-ring protein signature 85 104 9.9E-88 T 29-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 MC49_RS12550 5ef9b0ec1887d60e8beec9bc4a53b826 368 PRINTS PR01010 Flagellar P-ring protein signature 24 39 9.9E-88 T 29-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 MC49_RS12550 5ef9b0ec1887d60e8beec9bc4a53b826 368 PRINTS PR01010 Flagellar P-ring protein signature 107 124 9.9E-88 T 29-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 MC49_RS12550 5ef9b0ec1887d60e8beec9bc4a53b826 368 PRINTS PR01010 Flagellar P-ring protein signature 124 142 9.9E-88 T 29-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 MC49_RS00700 357a89366ac068ff85b45886d488f601 579 Pfam PF00664 ABC transporter transmembrane region 22 291 1.3E-38 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MC49_RS00700 357a89366ac068ff85b45886d488f601 579 Gene3D G3DSA:3.40.50.300 324 577 5.7E-67 T 29-03-2018 MC49_RS00700 357a89366ac068ff85b45886d488f601 579 SMART SM00382 361 547 7.8E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS00700 357a89366ac068ff85b45886d488f601 579 Pfam PF00005 ABC transporter 352 500 2.3E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS00700 357a89366ac068ff85b45886d488f601 579 Gene3D G3DSA:1.20.1560.10 1 323 1.9E-58 T 29-03-2018 MC49_RS00700 357a89366ac068ff85b45886d488f601 579 SUPERFAMILY SSF52540 330 572 1.41E-80 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS00700 357a89366ac068ff85b45886d488f601 579 ProSitePatterns PS00211 ABC transporters family signature. 473 487 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS00700 357a89366ac068ff85b45886d488f601 579 SUPERFAMILY SSF90123 7 323 5.36E-72 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MC49_RS10790 147b2d6c206a6f6db57b354205216a3c 677 PRINTS PR01041 Methionyl-tRNA synthetase signature 90 101 7.9E-26 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MC49_RS10790 147b2d6c206a6f6db57b354205216a3c 677 PRINTS PR01041 Methionyl-tRNA synthetase signature 42 56 7.9E-26 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MC49_RS10790 147b2d6c206a6f6db57b354205216a3c 677 PRINTS PR01041 Methionyl-tRNA synthetase signature 10 23 7.9E-26 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MC49_RS10790 147b2d6c206a6f6db57b354205216a3c 677 PRINTS PR01041 Methionyl-tRNA synthetase signature 384 395 7.9E-26 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MC49_RS10790 147b2d6c206a6f6db57b354205216a3c 677 PRINTS PR01041 Methionyl-tRNA synthetase signature 251 262 7.9E-26 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MC49_RS10790 147b2d6c206a6f6db57b354205216a3c 677 PRINTS PR01041 Methionyl-tRNA synthetase signature 291 306 7.9E-26 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MC49_RS10790 147b2d6c206a6f6db57b354205216a3c 677 Gene3D G3DSA:2.20.28.20 142 175 3.2E-16 T 29-03-2018 MC49_RS10790 147b2d6c206a6f6db57b354205216a3c 677 SUPERFAMILY SSF57770 142 176 5.62E-13 T 29-03-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MC49_RS10790 147b2d6c206a6f6db57b354205216a3c 677 Pfam PF09334 tRNA synthetases class I (M) 8 396 4.7E-165 T 29-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS10790 147b2d6c206a6f6db57b354205216a3c 677 Gene3D G3DSA:3.40.50.620 5 130 6.6E-26 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS10790 147b2d6c206a6f6db57b354205216a3c 677 SUPERFAMILY SSF52374 176 387 1.1E-104 T 29-03-2018 MC49_RS10790 147b2d6c206a6f6db57b354205216a3c 677 SUPERFAMILY SSF52374 6 141 1.1E-104 T 29-03-2018 MC49_RS10790 147b2d6c206a6f6db57b354205216a3c 677 Gene3D G3DSA:3.40.50.620 250 370 6.4E-24 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS10790 147b2d6c206a6f6db57b354205216a3c 677 Gene3D G3DSA:2.40.50.140 567 677 2.6E-24 T 29-03-2018 MC49_RS10790 147b2d6c206a6f6db57b354205216a3c 677 SUPERFAMILY SSF47323 390 547 1.87E-45 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS10790 147b2d6c206a6f6db57b354205216a3c 677 Gene3D G3DSA:1.10.730.10 373 536 1.5E-34 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS10790 147b2d6c206a6f6db57b354205216a3c 677 Pfam PF01588 Putative tRNA binding domain 581 674 1.6E-21 T 29-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 MC49_RS10790 147b2d6c206a6f6db57b354205216a3c 677 Hamap MF_00098 Methionine--tRNA ligase [metG]. 6 545 41.601 T 29-03-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MC49_RS10790 147b2d6c206a6f6db57b354205216a3c 677 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 8 535 1.8E-201 T 29-03-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MC49_RS10790 147b2d6c206a6f6db57b354205216a3c 677 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 15 26 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS10790 147b2d6c206a6f6db57b354205216a3c 677 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 539 677 1.6E-43 T 29-03-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MC49_RS10790 147b2d6c206a6f6db57b354205216a3c 677 SUPERFAMILY SSF50249 570 676 2.33E-28 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS10790 147b2d6c206a6f6db57b354205216a3c 677 Gene3D G3DSA:2.170.220.10 181 249 8.2E-17 T 29-03-2018 MC49_RS19145 701849c815597c0ee73bd10c59ba6d38 420 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 201 411 2.9E-64 T 29-03-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 MC49_RS19145 701849c815597c0ee73bd10c59ba6d38 420 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 9 81 1.9E-22 T 29-03-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 MC49_RS19145 701849c815597c0ee73bd10c59ba6d38 420 TIGRFAM TIGR00804 nupC: nucleoside transporter, NupC family 4 411 2.1E-146 T 29-03-2018 IPR018270 Concentrative nucleoside transporter, metazoan/bacterial GO:0005337|GO:0016020|GO:1901642 Reactome: R-HSA-83936 MC49_RS15695 fe7a1a329529104cde21d48a94e284e9 226 Gene3D G3DSA:1.20.120.260 95 219 5.1E-4 T 29-03-2018 IPR014773 Virulence factor YopE uncharacterised domain MC49_RS15695 fe7a1a329529104cde21d48a94e284e9 226 SUPERFAMILY SSF47233 102 195 2.22E-5 T 29-03-2018 IPR014773 Virulence factor YopE uncharacterised domain MC49_RS11070 d7d3e15b1f0d8c7eb537a53086d3137a 1189 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 20 191 6.6E-45 T 29-03-2018 IPR025199 DNA translocase FtsK, 4TM region MC49_RS11070 d7d3e15b1f0d8c7eb537a53086d3137a 1189 SMART SM00843 1121 1186 4.1E-40 T 29-03-2018 IPR018541 FtsK gamma domain MC49_RS11070 d7d3e15b1f0d8c7eb537a53086d3137a 1189 Pfam PF01580 FtsK/SpoIIIE family 808 1021 1.4E-71 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 MC49_RS11070 d7d3e15b1f0d8c7eb537a53086d3137a 1189 Gene3D G3DSA:3.40.50.300 563 1060 3.5E-53 T 29-03-2018 MC49_RS11070 d7d3e15b1f0d8c7eb537a53086d3137a 1189 Gene3D G3DSA:1.10.10.10 1123 1177 1.5E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS11070 d7d3e15b1f0d8c7eb537a53086d3137a 1189 SUPERFAMILY SSF46785 1121 1186 6.33E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS11070 d7d3e15b1f0d8c7eb537a53086d3137a 1189 Pfam PF09397 Ftsk gamma domain 1123 1183 3.0E-27 T 29-03-2018 IPR018541 FtsK gamma domain MC49_RS11070 d7d3e15b1f0d8c7eb537a53086d3137a 1189 SUPERFAMILY SSF52540 782 1094 6.24E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS16435 102f7e16e46c47fcd516d85da195361e 463 Gene3D G3DSA:2.30.38.10 284 354 1.6E-4 T 29-03-2018 MC49_RS16435 102f7e16e46c47fcd516d85da195361e 463 SUPERFAMILY SSF56801 9 459 7.2E-81 T 29-03-2018 MC49_RS16435 102f7e16e46c47fcd516d85da195361e 463 Pfam PF00501 AMP-binding enzyme 11 359 2.7E-48 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MC49_RS16435 102f7e16e46c47fcd516d85da195361e 463 ProSitePatterns PS00455 Putative AMP-binding domain signature. 140 151 - T 29-03-2018 IPR020845 AMP-binding, conserved site MC49_RS16435 102f7e16e46c47fcd516d85da195361e 463 Gene3D G3DSA:3.40.50.980 7 145 3.6E-24 T 29-03-2018 MC49_RS16435 102f7e16e46c47fcd516d85da195361e 463 Gene3D G3DSA:3.30.300.30 355 461 1.9E-8 T 29-03-2018 MC49_RS16435 102f7e16e46c47fcd516d85da195361e 463 Gene3D G3DSA:3.40.50.980 146 283 1.8E-30 T 29-03-2018 MC49_RS14735 a853f256f187bd9b0826fa5ee54c2876 406 SUPERFAMILY SSF103473 12 397 4.32E-48 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS14735 a853f256f187bd9b0826fa5ee54c2876 406 Gene3D G3DSA:1.20.1250.20 14 200 4.2E-21 T 29-03-2018 MC49_RS14735 a853f256f187bd9b0826fa5ee54c2876 406 Pfam PF07690 Major Facilitator Superfamily 25 332 1.2E-29 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS14735 a853f256f187bd9b0826fa5ee54c2876 406 Gene3D G3DSA:1.20.1250.20 201 405 3.9E-13 T 29-03-2018 MC49_RS08590 be55b9e298f93c84ae42f396f5b58e3f 400 Gene3D G3DSA:3.40.50.1970 33 207 2.3E-42 T 29-03-2018 MC49_RS08590 be55b9e298f93c84ae42f396f5b58e3f 400 SUPERFAMILY SSF56796 27 399 2.09E-119 T 29-03-2018 MC49_RS08590 be55b9e298f93c84ae42f396f5b58e3f 400 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 284 304 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 MC49_RS08590 be55b9e298f93c84ae42f396f5b58e3f 400 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 197 225 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 MC49_RS08590 be55b9e298f93c84ae42f396f5b58e3f 400 Gene3D G3DSA:1.20.1090.10 208 400 1.4E-60 T 29-03-2018 MC49_RS08590 be55b9e298f93c84ae42f396f5b58e3f 400 Pfam PF00465 Iron-containing alcohol dehydrogenase 33 393 8.4E-116 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 MC49_RS01490 a76ffc6208dc506b1cd1c594a16dd963 345 SMART SM00062 44 262 2.2E-4 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MC49_RS01490 a76ffc6208dc506b1cd1c594a16dd963 345 SUPERFAMILY SSF53850 43 259 6.41E-36 T 29-03-2018 MC49_RS01490 a76ffc6208dc506b1cd1c594a16dd963 345 Gene3D G3DSA:3.40.190.10 39 136 3.2E-12 T 29-03-2018 MC49_RS01490 a76ffc6208dc506b1cd1c594a16dd963 345 Pfam PF13379 NMT1-like family 42 259 1.1E-13 T 29-03-2018 MC49_RS01490 a76ffc6208dc506b1cd1c594a16dd963 345 Gene3D G3DSA:3.40.190.10 140 331 1.1E-28 T 29-03-2018 MC49_RS15635 8ccb10f474a9390f64ed2a2e9cc0c697 262 SUPERFAMILY SSF51735 6 253 2.24E-63 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS15635 8ccb10f474a9390f64ed2a2e9cc0c697 262 Gene3D G3DSA:3.40.50.720 3 261 6.0E-44 T 29-03-2018 MC49_RS15635 8ccb10f474a9390f64ed2a2e9cc0c697 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.9E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS15635 8ccb10f474a9390f64ed2a2e9cc0c697 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 2.9E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS15635 8ccb10f474a9390f64ed2a2e9cc0c697 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 2.9E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS15635 8ccb10f474a9390f64ed2a2e9cc0c697 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 252 1.3E-85 T 29-03-2018 MC49_RS15635 8ccb10f474a9390f64ed2a2e9cc0c697 262 PIRSF PIRSF000094 1 260 7.3E-124 T 29-03-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MC49_RS18210 1bd947d8a1d3beece7f5beed5c6fac0e 325 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 319 4.3E-27 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 MC49_RS18210 1bd947d8a1d3beece7f5beed5c6fac0e 325 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 108 287 3.1E-62 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MC49_RS18210 1bd947d8a1d3beece7f5beed5c6fac0e 325 SUPERFAMILY SSF51735 100 288 1.42E-57 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS18210 1bd947d8a1d3beece7f5beed5c6fac0e 325 SUPERFAMILY SSF52283 1 133 1.42E-27 T 29-03-2018 MC49_RS18210 1bd947d8a1d3beece7f5beed5c6fac0e 325 Gene3D G3DSA:3.40.50.720 1 114 1.2E-26 T 29-03-2018 MC49_RS18210 1bd947d8a1d3beece7f5beed5c6fac0e 325 Gene3D G3DSA:3.40.50.720 115 290 4.3E-55 T 29-03-2018 MC49_RS18210 1bd947d8a1d3beece7f5beed5c6fac0e 325 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 226 242 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site MC49_RS01015 8d2afbeaa543f892741f0aad2cd84cfb 616 Pfam PF04539 Sigma-70 region 3 461 536 6.9E-29 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS01015 8d2afbeaa543f892741f0aad2cd84cfb 616 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 378 614 6.0E-121 T 29-03-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 MC49_RS01015 8d2afbeaa543f892741f0aad2cd84cfb 616 Pfam PF04546 Sigma-70, non-essential region 139 351 1.8E-74 T 29-03-2018 IPR007631 RNA polymerase sigma factor 70, non-essential domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS01015 8d2afbeaa543f892741f0aad2cd84cfb 616 PRINTS PR00046 Major sigma-70 factor signature 406 419 3.1E-31 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS01015 8d2afbeaa543f892741f0aad2cd84cfb 616 PRINTS PR00046 Major sigma-70 factor signature 575 590 3.1E-31 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS01015 8d2afbeaa543f892741f0aad2cd84cfb 616 PRINTS PR00046 Major sigma-70 factor signature 430 438 3.1E-31 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS01015 8d2afbeaa543f892741f0aad2cd84cfb 616 PRINTS PR00046 Major sigma-70 factor signature 590 601 3.1E-31 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS01015 8d2afbeaa543f892741f0aad2cd84cfb 616 PRINTS PR00046 Major sigma-70 factor signature 554 566 3.1E-31 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS01015 8d2afbeaa543f892741f0aad2cd84cfb 616 SUPERFAMILY SSF88946 115 449 8.11E-103 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS01015 8d2afbeaa543f892741f0aad2cd84cfb 616 SUPERFAMILY SSF88659 512 614 4.91E-26 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS01015 8d2afbeaa543f892741f0aad2cd84cfb 616 Pfam PF04545 Sigma-70, region 4 550 603 1.8E-19 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS01015 8d2afbeaa543f892741f0aad2cd84cfb 616 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 4 615 46.799 T 29-03-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 MC49_RS01015 8d2afbeaa543f892741f0aad2cd84cfb 616 SUPERFAMILY SSF88659 455 528 2.62E-20 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS01015 8d2afbeaa543f892741f0aad2cd84cfb 616 Pfam PF04542 Sigma-70 region 2 382 451 1.7E-21 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS01015 8d2afbeaa543f892741f0aad2cd84cfb 616 Gene3D G3DSA:1.10.10.10 545 615 1.0E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS01015 8d2afbeaa543f892741f0aad2cd84cfb 616 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 378 603 9.6E-39 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS01015 8d2afbeaa543f892741f0aad2cd84cfb 616 Pfam PF00140 Sigma-70 factor, region 1.2 98 128 1.8E-12 T 29-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS01015 8d2afbeaa543f892741f0aad2cd84cfb 616 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 406 419 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS01015 8d2afbeaa543f892741f0aad2cd84cfb 616 Gene3D G3DSA:1.10.601.10 3 114 2.4E-14 T 29-03-2018 MC49_RS01015 8d2afbeaa543f892741f0aad2cd84cfb 616 Gene3D G3DSA:1.10.601.10 115 451 1.6E-108 T 29-03-2018 MC49_RS01015 8d2afbeaa543f892741f0aad2cd84cfb 616 Gene3D G3DSA:1.10.10.10 452 502 1.4E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS01015 8d2afbeaa543f892741f0aad2cd84cfb 616 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 575 601 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS01015 8d2afbeaa543f892741f0aad2cd84cfb 616 Pfam PF03979 Sigma-70 factor, region 1.1 4 79 3.8E-30 T 29-03-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 MC49_RS18540 6e2e8785dcbeadd0b0ac10b1fe353c3c 887 SUPERFAMILY SSF52518 59 468 3.65E-142 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MC49_RS18540 6e2e8785dcbeadd0b0ac10b1fe353c3c 887 Gene3D G3DSA:3.40.50.970 472 706 4.4E-65 T 29-03-2018 MC49_RS18540 6e2e8785dcbeadd0b0ac10b1fe353c3c 887 SUPERFAMILY SSF52922 702 885 2.62E-60 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MC49_RS18540 6e2e8785dcbeadd0b0ac10b1fe353c3c 887 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 6 886 0.0 T 29-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 MC49_RS18540 6e2e8785dcbeadd0b0ac10b1fe353c3c 887 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 105 294 5.8E-9 T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MC49_RS18540 6e2e8785dcbeadd0b0ac10b1fe353c3c 887 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 361 428 3.0E-5 T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MC49_RS18540 6e2e8785dcbeadd0b0ac10b1fe353c3c 887 Gene3D G3DSA:3.40.50.970 57 471 1.5E-84 T 29-03-2018 MC49_RS18540 6e2e8785dcbeadd0b0ac10b1fe353c3c 887 Gene3D G3DSA:3.40.50.920 707 887 4.3E-40 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MC49_RS18540 6e2e8785dcbeadd0b0ac10b1fe353c3c 887 SUPERFAMILY SSF52518 474 701 1.15E-97 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MC49_RS18540 6e2e8785dcbeadd0b0ac10b1fe353c3c 887 PIRSF PIRSF000156 1 887 0.0 T 29-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 MC49_RS09045 17186eace715508b1e3c885b52876d46 236 TIGRFAM TIGR00230 sfsA: sugar fermentation stimulation protein 1 222 3.6E-80 T 29-03-2018 IPR005224 Sugar fermentation stimulation protein MC49_RS09045 17186eace715508b1e3c885b52876d46 236 Hamap MF_00095 Sugar fermentation stimulation protein A [sfsA]. 1 234 55.008 T 29-03-2018 IPR005224 Sugar fermentation stimulation protein MC49_RS09045 17186eace715508b1e3c885b52876d46 236 Pfam PF03749 Sugar fermentation stimulation protein 13 225 7.9E-74 T 29-03-2018 IPR005224 Sugar fermentation stimulation protein MC49_RS01920 bf02a16ff12f68b6257d88138b1d4e8b 432 Pfam PF00890 FAD binding domain 4 403 1.5E-51 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MC49_RS01920 bf02a16ff12f68b6257d88138b1d4e8b 432 Gene3D G3DSA:3.50.50.60 1 419 3.6E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS01920 bf02a16ff12f68b6257d88138b1d4e8b 432 SUPERFAMILY SSF51905 253 420 8.23E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS01920 bf02a16ff12f68b6257d88138b1d4e8b 432 SUPERFAMILY SSF51905 1 71 8.23E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS01920 bf02a16ff12f68b6257d88138b1d4e8b 432 SUPERFAMILY SSF51905 132 199 8.23E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS01920 bf02a16ff12f68b6257d88138b1d4e8b 432 PIRSF PIRSF000141 1 422 1.5E-155 T 29-03-2018 IPR009158 Glycerol-3-phosphate dehydrogenase, GlpB subunit GO:0004368|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 MC49_RS01920 bf02a16ff12f68b6257d88138b1d4e8b 432 Hamap MF_00753 Anaerobic glycerol-3-phosphate dehydrogenase subunit B [glpB]. 1 419 44.298 T 29-03-2018 IPR009158 Glycerol-3-phosphate dehydrogenase, GlpB subunit GO:0004368|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 MC49_RS01920 bf02a16ff12f68b6257d88138b1d4e8b 432 TIGRFAM TIGR03378 glycerol3P_GlpB: glycerol-3-phosphate dehydrogenase, anaerobic, B subunit 3 416 6.0E-155 T 29-03-2018 IPR009158 Glycerol-3-phosphate dehydrogenase, GlpB subunit GO:0004368|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 MC49_RS12745 8f599e74bff549dc0841b0115019dbb4 514 Pfam PF00884 Sulfatase 221 442 5.1E-22 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 MC49_RS12745 8f599e74bff549dc0841b0115019dbb4 514 SUPERFAMILY SSF53649 220 430 2.62E-21 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MC49_RS12745 8f599e74bff549dc0841b0115019dbb4 514 Gene3D G3DSA:3.40.720.10 216 473 1.8E-24 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 MC49_RS14525 86bcfdf0fd2139cf65a0c30ad1fbbed6 332 Gene3D G3DSA:1.10.3470.10 2 332 6.3E-65 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like MC49_RS14525 86bcfdf0fd2139cf65a0c30ad1fbbed6 332 SUPERFAMILY SSF81345 7 327 1.83E-71 T 29-03-2018 IPR029022 ABC transporter, BtuC-like MC49_RS14525 86bcfdf0fd2139cf65a0c30ad1fbbed6 332 Pfam PF01032 FecCD transport family 15 327 8.8E-82 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 MC49_RS11350 c53f016c24c8dd5e9730e44c5e534bc8 92 Gene3D G3DSA:3.30.70.100 2 92 3.7E-25 T 29-03-2018 MC49_RS11350 c53f016c24c8dd5e9730e44c5e534bc8 92 Pfam PF00708 Acylphosphatase 6 84 4.7E-23 T 29-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 MC49_RS11350 c53f016c24c8dd5e9730e44c5e534bc8 92 ProSitePatterns PS00151 Acylphosphatase signature 2. 33 49 - T 29-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 MC49_RS11350 c53f016c24c8dd5e9730e44c5e534bc8 92 Hamap MF_01450 Acylphosphatase [yccX]. 1 90 27.919 T 29-03-2018 IPR028627 Acylphosphatase, bacteria GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 MC49_RS11350 c53f016c24c8dd5e9730e44c5e534bc8 92 ProSitePatterns PS00150 Acylphosphatase signature 1. 9 19 - T 29-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 MC49_RS11350 c53f016c24c8dd5e9730e44c5e534bc8 92 SUPERFAMILY SSF54975 3 90 1.53E-27 T 29-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 MC49_RS10615 985f5b7ff161bbc0eda991b4970b3331 159 SUPERFAMILY SSF55040 11 155 6.41E-62 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 MC49_RS10615 985f5b7ff161bbc0eda991b4970b3331 159 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 2 158 36.127 T 29-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 MC49_RS10615 985f5b7ff161bbc0eda991b4970b3331 159 Gene3D G3DSA:3.30.70.640 2 158 9.2E-69 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 MC49_RS10615 985f5b7ff161bbc0eda991b4970b3331 159 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 152 6.7E-72 T 29-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 MC49_RS10615 985f5b7ff161bbc0eda991b4970b3331 159 Pfam PF01967 MoaC family 15 150 1.5E-55 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 MC49_RS18410 6b24bb7637487bf1dca8a552befde0d0 172 Gene3D G3DSA:3.40.50.360 74 172 2.1E-16 T 29-03-2018 IPR029039 Flavoprotein-like domain MC49_RS18410 6b24bb7637487bf1dca8a552befde0d0 172 Gene3D G3DSA:3.40.50.360 1 73 3.7E-14 T 29-03-2018 IPR029039 Flavoprotein-like domain MC49_RS18410 6b24bb7637487bf1dca8a552befde0d0 172 Pfam PF00258 Flavodoxin 5 160 9.2E-27 T 29-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 MC49_RS18410 6b24bb7637487bf1dca8a552befde0d0 172 ProSitePatterns PS00201 Flavodoxin signature. 5 21 - T 29-03-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 MC49_RS18410 6b24bb7637487bf1dca8a552befde0d0 172 PIRSF PIRSF038996 1 171 1.2E-53 T 29-03-2018 IPR010086 Flavodoxin, long chain GO:0010181 MC49_RS18410 6b24bb7637487bf1dca8a552befde0d0 172 SUPERFAMILY SSF52218 1 168 8.07E-46 T 29-03-2018 IPR029039 Flavoprotein-like domain MC49_RS18410 6b24bb7637487bf1dca8a552befde0d0 172 TIGRFAM TIGR01752 flav_long: flavodoxin 2 168 6.9E-67 T 29-03-2018 IPR010086 Flavodoxin, long chain GO:0010181 MC49_RS03745 a27cb6608afa642cde2bfc111ff7fda9 245 SUPERFAMILY SSF69618 1 244 2.62E-56 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MC49_RS03745 a27cb6608afa642cde2bfc111ff7fda9 245 Gene3D G3DSA:3.40.50.10090 1 118 2.0E-16 T 29-03-2018 MC49_RS03745 a27cb6608afa642cde2bfc111ff7fda9 245 Gene3D G3DSA:3.40.50.10090 121 245 4.6E-23 T 29-03-2018 MC49_RS03745 a27cb6608afa642cde2bfc111ff7fda9 245 Pfam PF02602 Uroporphyrinogen-III synthase HemD 14 242 6.7E-38 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MC49_RS02910 f1bb160553942e9406ab784040f0a2d4 233 Pfam PF00072 Response regulator receiver domain 28 139 1.3E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS02910 f1bb160553942e9406ab784040f0a2d4 233 Pfam PF00196 Bacterial regulatory proteins, luxR family 174 228 7.2E-25 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS02910 f1bb160553942e9406ab784040f0a2d4 233 SMART SM00421 172 229 6.5E-27 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS02910 f1bb160553942e9406ab784040f0a2d4 233 SMART SM00448 26 139 1.4E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS02910 f1bb160553942e9406ab784040f0a2d4 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 205 217 1.7E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS02910 f1bb160553942e9406ab784040f0a2d4 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 189 1.7E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS02910 f1bb160553942e9406ab784040f0a2d4 233 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 189 205 1.7E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS02910 f1bb160553942e9406ab784040f0a2d4 233 Gene3D G3DSA:3.40.50.2300 26 158 5.3E-34 T 29-03-2018 MC49_RS02910 f1bb160553942e9406ab784040f0a2d4 233 SUPERFAMILY SSF52172 26 155 3.7E-34 T 29-03-2018 IPR011006 CheY-like superfamily MC49_RS02910 f1bb160553942e9406ab784040f0a2d4 233 Gene3D G3DSA:1.10.10.10 159 233 1.6E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS02910 f1bb160553942e9406ab784040f0a2d4 233 SUPERFAMILY SSF46894 165 232 3.13E-21 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MC49_RS02910 f1bb160553942e9406ab784040f0a2d4 233 ProSitePatterns PS00622 LuxR-type HTH domain signature. 189 216 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS01085 018f8fd6f5584031b28b6e2d3d4ad451 154 SUPERFAMILY SSF47598 4 42 3.06E-6 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 MC49_RS01085 018f8fd6f5584031b28b6e2d3d4ad451 154 Gene3D G3DSA:1.10.1220.10 1 80 1.8E-6 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 MC49_RS01085 018f8fd6f5584031b28b6e2d3d4ad451 154 Pfam PF01402 Ribbon-helix-helix protein, copG family 10 41 2.4E-4 T 29-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 MC49_RS05715 e8b2fb56287501f9d2069d8c5b1b7a32 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 24 255 2.1E-25 T 29-03-2018 MC49_RS05715 e8b2fb56287501f9d2069d8c5b1b7a32 256 SUPERFAMILY SSF51735 6 256 3.27E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS05715 e8b2fb56287501f9d2069d8c5b1b7a32 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 2.9E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS05715 e8b2fb56287501f9d2069d8c5b1b7a32 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 2.9E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS05715 e8b2fb56287501f9d2069d8c5b1b7a32 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 2.9E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS05715 e8b2fb56287501f9d2069d8c5b1b7a32 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.9E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS05715 e8b2fb56287501f9d2069d8c5b1b7a32 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 2.9E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS05715 e8b2fb56287501f9d2069d8c5b1b7a32 256 Gene3D G3DSA:3.40.50.720 1 256 9.2E-37 T 29-03-2018 MC49_RS02835 a6aa68c1d487d89b2da02fea0f329310 524 Gene3D G3DSA:3.40.30.10 1 94 1.3E-29 T 29-03-2018 MC49_RS02835 a6aa68c1d487d89b2da02fea0f329310 524 PIRSF PIRSF000238 1 521 2.5E-259 T 29-03-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 MC49_RS02835 a6aa68c1d487d89b2da02fea0f329310 524 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 444 465 1.5E-63 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MC49_RS02835 a6aa68c1d487d89b2da02fea0f329310 524 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 246 261 1.5E-63 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MC49_RS02835 a6aa68c1d487d89b2da02fea0f329310 524 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 478 496 1.5E-63 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MC49_RS02835 a6aa68c1d487d89b2da02fea0f329310 524 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 353 377 1.5E-63 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MC49_RS02835 a6aa68c1d487d89b2da02fea0f329310 524 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 338 350 1.5E-63 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MC49_RS02835 a6aa68c1d487d89b2da02fea0f329310 524 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 316 324 1.5E-63 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MC49_RS02835 a6aa68c1d487d89b2da02fea0f329310 524 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 405 421 1.5E-63 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MC49_RS02835 a6aa68c1d487d89b2da02fea0f329310 524 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 266 276 1.5E-63 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MC49_RS02835 a6aa68c1d487d89b2da02fea0f329310 524 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 214 236 1.5E-63 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MC49_RS02835 a6aa68c1d487d89b2da02fea0f329310 524 Gene3D G3DSA:3.50.50.60 443 523 7.0E-10 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS02835 a6aa68c1d487d89b2da02fea0f329310 524 Gene3D G3DSA:3.40.30.10 103 197 1.4E-7 T 29-03-2018 MC49_RS02835 a6aa68c1d487d89b2da02fea0f329310 524 SUPERFAMILY SSF51905 205 514 9.43E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS02835 a6aa68c1d487d89b2da02fea0f329310 524 Gene3D G3DSA:3.50.50.60 341 442 1.5E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS02835 a6aa68c1d487d89b2da02fea0f329310 524 Pfam PF13192 Thioredoxin domain 126 194 4.2E-7 T 29-03-2018 IPR012336 Thioredoxin-like fold MC49_RS02835 a6aa68c1d487d89b2da02fea0f329310 524 Gene3D G3DSA:3.40.50.720 208 340 7.5E-20 T 29-03-2018 MC49_RS02835 a6aa68c1d487d89b2da02fea0f329310 524 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 345 365 - T 29-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 MC49_RS02835 a6aa68c1d487d89b2da02fea0f329310 524 SUPERFAMILY SSF52833 106 196 6.66E-24 T 29-03-2018 IPR012336 Thioredoxin-like fold MC49_RS02835 a6aa68c1d487d89b2da02fea0f329310 524 SUPERFAMILY SSF52833 1 101 1.23E-30 T 29-03-2018 IPR012336 Thioredoxin-like fold MC49_RS02835 a6aa68c1d487d89b2da02fea0f329310 524 TIGRFAM TIGR03140 AhpF: alkyl hydroperoxide reductase subunit F 1 517 2.4E-241 T 29-03-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 MC49_RS02835 a6aa68c1d487d89b2da02fea0f329310 524 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 213 502 1.7E-41 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS02835 a6aa68c1d487d89b2da02fea0f329310 524 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 468 490 1.0E-36 T 29-03-2018 MC49_RS02835 a6aa68c1d487d89b2da02fea0f329310 524 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 315 333 1.0E-36 T 29-03-2018 MC49_RS02835 a6aa68c1d487d89b2da02fea0f329310 524 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 215 234 1.0E-36 T 29-03-2018 MC49_RS02835 a6aa68c1d487d89b2da02fea0f329310 524 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 357 375 1.0E-36 T 29-03-2018 MC49_RS02835 a6aa68c1d487d89b2da02fea0f329310 524 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 442 458 1.0E-36 T 29-03-2018 MC49_RS04005 f7746197cdacd8214548b6e890839ba4 430 Pfam PF01189 16S rRNA methyltransferase RsmB/F 240 423 1.1E-72 T 29-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MC49_RS04005 f7746197cdacd8214548b6e890839ba4 430 Pfam PF01029 NusB family 6 127 3.0E-22 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 MC49_RS04005 f7746197cdacd8214548b6e890839ba4 430 SUPERFAMILY SSF48013 6 149 8.83E-34 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 MC49_RS04005 f7746197cdacd8214548b6e890839ba4 430 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 8 427 4.6E-168 T 29-03-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MC49_RS04005 f7746197cdacd8214548b6e890839ba4 430 SUPERFAMILY SSF53335 140 425 4.76E-76 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS04005 f7746197cdacd8214548b6e890839ba4 430 Gene3D G3DSA:3.40.50.150 231 429 1.1E-52 T 29-03-2018 MC49_RS04005 f7746197cdacd8214548b6e890839ba4 430 Gene3D G3DSA:1.10.940.10 1 145 3.1E-30 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 MC49_RS04005 f7746197cdacd8214548b6e890839ba4 430 Gene3D G3DSA:3.30.70.1170 173 230 2.5E-16 T 29-03-2018 MC49_RS04005 f7746197cdacd8214548b6e890839ba4 430 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 367 383 1.8E-31 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MC49_RS04005 f7746197cdacd8214548b6e890839ba4 430 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 222 236 1.8E-31 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MC49_RS04005 f7746197cdacd8214548b6e890839ba4 430 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 317 329 1.8E-31 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MC49_RS04005 f7746197cdacd8214548b6e890839ba4 430 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 408 425 1.8E-31 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MC49_RS04005 f7746197cdacd8214548b6e890839ba4 430 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 251 261 1.8E-31 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MC49_RS04005 f7746197cdacd8214548b6e890839ba4 430 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 316 327 - T 29-03-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MC49_RS04005 f7746197cdacd8214548b6e890839ba4 430 Gene3D G3DSA:1.10.287.730 146 172 3.1E-11 T 29-03-2018 MC49_RS06365 4b9d22cd89e63ff0938c78450e0395f7 119 Gene3D G3DSA:3.40.1260.10 4 117 3.5E-21 T 29-03-2018 MC49_RS06365 4b9d22cd89e63ff0938c78450e0395f7 119 SUPERFAMILY SSF75169 2 119 9.03E-33 T 29-03-2018 IPR027396 DsrEFH-like MC49_RS06365 4b9d22cd89e63ff0938c78450e0395f7 119 Pfam PF02635 DsrE/DsrF-like family 2 119 1.4E-22 T 29-03-2018 IPR003787 Sulphur relay, DsrE/F-like protein MC49_RS06365 4b9d22cd89e63ff0938c78450e0395f7 119 TIGRFAM TIGR03010 sulf_tusC_dsrF: sulfur relay protein TusC/DsrF 3 119 1.0E-43 T 29-03-2018 IPR017462 Sulphur relay, TusC/DsrF MC49_RS18535 4e4a94e94f7c0f9814284a775306b6fb 628 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 25 54 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MC49_RS18535 4e4a94e94f7c0f9814284a775306b6fb 628 SUPERFAMILY SSF51230 103 195 4.97E-23 T 29-03-2018 IPR011053 Single hybrid motif MC49_RS18535 4e4a94e94f7c0f9814284a775306b6fb 628 SUPERFAMILY SSF47005 319 364 1.83E-13 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 MC49_RS18535 4e4a94e94f7c0f9814284a775306b6fb 628 TIGRFAM TIGR01348 PDHac_trf_long: dihydrolipoyllysine-residue acetyltransferase 188 628 2.7E-214 T 29-03-2018 IPR006256 Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex GO:0004742|GO:0006096|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 MC49_RS18535 4e4a94e94f7c0f9814284a775306b6fb 628 SUPERFAMILY SSF52777 386 626 3.83E-80 T 29-03-2018 MC49_RS18535 4e4a94e94f7c0f9814284a775306b6fb 628 Pfam PF00364 Biotin-requiring enzyme 104 174 2.3E-20 T 29-03-2018 IPR000089 Biotin/lipoyl attachment MC49_RS18535 4e4a94e94f7c0f9814284a775306b6fb 628 Pfam PF00364 Biotin-requiring enzyme 204 274 2.8E-20 T 29-03-2018 IPR000089 Biotin/lipoyl attachment MC49_RS18535 4e4a94e94f7c0f9814284a775306b6fb 628 Pfam PF00364 Biotin-requiring enzyme 4 73 3.8E-21 T 29-03-2018 IPR000089 Biotin/lipoyl attachment MC49_RS18535 4e4a94e94f7c0f9814284a775306b6fb 628 Gene3D G3DSA:3.30.559.10 384 628 3.1E-81 T 29-03-2018 MC49_RS18535 4e4a94e94f7c0f9814284a775306b6fb 628 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 126 155 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MC49_RS18535 4e4a94e94f7c0f9814284a775306b6fb 628 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 226 255 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MC49_RS18535 4e4a94e94f7c0f9814284a775306b6fb 628 Gene3D G3DSA:3.90.1170.30 1 43 2.4E-8 T 29-03-2018 MC49_RS18535 4e4a94e94f7c0f9814284a775306b6fb 628 Gene3D G3DSA:3.90.1170.30 145 245 6.7E-23 T 29-03-2018 MC49_RS18535 4e4a94e94f7c0f9814284a775306b6fb 628 Gene3D G3DSA:3.90.1170.30 44 144 1.4E-23 T 29-03-2018 MC49_RS18535 4e4a94e94f7c0f9814284a775306b6fb 628 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 397 627 4.9E-80 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 MC49_RS18535 4e4a94e94f7c0f9814284a775306b6fb 628 Pfam PF02817 e3 binding domain 325 360 3.1E-15 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 MC49_RS18535 4e4a94e94f7c0f9814284a775306b6fb 628 SUPERFAMILY SSF51230 204 295 1.3E-22 T 29-03-2018 IPR011053 Single hybrid motif MC49_RS18535 4e4a94e94f7c0f9814284a775306b6fb 628 Gene3D G3DSA:4.10.320.10 318 379 7.9E-20 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 MC49_RS18535 4e4a94e94f7c0f9814284a775306b6fb 628 Gene3D G3DSA:2.40.50.100 246 317 6.3E-10 T 29-03-2018 MC49_RS18535 4e4a94e94f7c0f9814284a775306b6fb 628 SUPERFAMILY SSF51230 1 94 1.16E-23 T 29-03-2018 IPR011053 Single hybrid motif MC49_RS09885 7ee653f3b998f8f5d9ed820146de124f 250 Gene3D G3DSA:1.10.1270.20 170 250 1.0E-33 T 29-03-2018 MC49_RS09885 7ee653f3b998f8f5d9ed820146de124f 250 Gene3D G3DSA:3.40.1280.10 1 169 1.8E-74 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MC49_RS09885 7ee653f3b998f8f5d9ed820146de124f 250 PIRSF PIRSF000386 1 249 2.3E-102 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MC49_RS09885 7ee653f3b998f8f5d9ed820146de124f 250 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 234 3.2E-108 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MC49_RS09885 7ee653f3b998f8f5d9ed820146de124f 250 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 250 119.953 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MC49_RS09885 7ee653f3b998f8f5d9ed820146de124f 250 SUPERFAMILY SSF75217 1 245 1.37E-103 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases MC49_RS09885 7ee653f3b998f8f5d9ed820146de124f 250 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 221 9.3E-70 T 29-03-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MC49_RS04045 72319eddf55cd58cf0cfa6b440c5527e 129 Pfam PF00411 Ribosomal protein S11 19 128 3.4E-54 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 MC49_RS04045 72319eddf55cd58cf0cfa6b440c5527e 129 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 7 129 32.65 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 MC49_RS04045 72319eddf55cd58cf0cfa6b440c5527e 129 PIRSF PIRSF002131 1 129 9.3E-53 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 MC49_RS04045 72319eddf55cd58cf0cfa6b440c5527e 129 ProSitePatterns PS00054 Ribosomal protein S11 signature. 97 119 - T 29-03-2018 IPR018102 Ribosomal S11, conserved site MC49_RS04045 72319eddf55cd58cf0cfa6b440c5527e 129 SUPERFAMILY SSF53137 14 129 7.19E-48 T 29-03-2018 MC49_RS04045 72319eddf55cd58cf0cfa6b440c5527e 129 Gene3D G3DSA:3.30.420.80 5 129 6.3E-45 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 MC49_RS04045 72319eddf55cd58cf0cfa6b440c5527e 129 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 10 126 2.7E-55 T 29-03-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS11035 6b6b207789eb3ca39d7c686968c2bd12 761 Gene3D G3DSA:1.10.1780.10 1 142 1.6E-24 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 MC49_RS11035 6b6b207789eb3ca39d7c686968c2bd12 761 Gene3D G3DSA:3.40.50.300 478 661 3.3E-29 T 29-03-2018 MC49_RS11035 6b6b207789eb3ca39d7c686968c2bd12 761 Gene3D G3DSA:1.10.8.60 662 759 4.7E-23 T 29-03-2018 MC49_RS11035 6b6b207789eb3ca39d7c686968c2bd12 761 Gene3D G3DSA:3.40.50.300 168 353 7.1E-31 T 29-03-2018 MC49_RS11035 6b6b207789eb3ca39d7c686968c2bd12 761 SMART SM01086 656 747 4.2E-35 T 29-03-2018 IPR019489 Clp ATPase, C-terminal MC49_RS11035 6b6b207789eb3ca39d7c686968c2bd12 761 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 214 346 1.9E-13 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MC49_RS11035 6b6b207789eb3ca39d7c686968c2bd12 761 SUPERFAMILY SSF52540 440 742 5.55E-73 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS11035 6b6b207789eb3ca39d7c686968c2bd12 761 Pfam PF07724 AAA domain (Cdc48 subfamily) 489 648 1.5E-47 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MC49_RS11035 6b6b207789eb3ca39d7c686968c2bd12 761 TIGRFAM TIGR02639 ClpA: ATP-dependent Clp protease ATP-binding subunit ClpA 3 737 0.0 T 29-03-2018 IPR013461 ATP-dependent Clp protease ATP-binding subunit ClpA GO:0004176 MC49_RS11035 6b6b207789eb3ca39d7c686968c2bd12 761 SUPERFAMILY SSF52540 171 428 8.81E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS11035 6b6b207789eb3ca39d7c686968c2bd12 761 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 305 317 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 MC49_RS11035 6b6b207789eb3ca39d7c686968c2bd12 761 Gene3D G3DSA:1.10.8.60 354 477 2.1E-26 T 29-03-2018 MC49_RS11035 6b6b207789eb3ca39d7c686968c2bd12 761 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 656 735 8.8E-23 T 29-03-2018 IPR019489 Clp ATPase, C-terminal MC49_RS11035 6b6b207789eb3ca39d7c686968c2bd12 761 SUPERFAMILY SSF81923 1 140 1.24E-56 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 MC49_RS11035 6b6b207789eb3ca39d7c686968c2bd12 761 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 521 539 - T 29-03-2018 IPR028299 ClpA/B, conserved site 2 MC49_RS11035 6b6b207789eb3ca39d7c686968c2bd12 761 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 13 62 1.7E-12 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 MC49_RS11035 6b6b207789eb3ca39d7c686968c2bd12 761 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 598 612 1.5E-34 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 MC49_RS11035 6b6b207789eb3ca39d7c686968c2bd12 761 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 494 512 1.5E-34 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 MC49_RS11035 6b6b207789eb3ca39d7c686968c2bd12 761 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 536 554 1.5E-34 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 MC49_RS11035 6b6b207789eb3ca39d7c686968c2bd12 761 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 565 583 1.5E-34 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 MC49_RS11035 6b6b207789eb3ca39d7c686968c2bd12 761 SMART SM00382 490 657 9.0E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS11035 6b6b207789eb3ca39d7c686968c2bd12 761 SMART SM00382 209 353 1.6E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS16060 2e8f26501c79197b1bde0fcd95235bf5 209 ProSitePatterns PS00622 LuxR-type HTH domain signature. 162 189 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS16060 2e8f26501c79197b1bde0fcd95235bf5 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 198 1.8E-20 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS16060 2e8f26501c79197b1bde0fcd95235bf5 209 Gene3D G3DSA:1.10.10.10 129 209 4.4E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS16060 2e8f26501c79197b1bde0fcd95235bf5 209 Gene3D G3DSA:3.40.50.2300 3 128 1.4E-19 T 29-03-2018 MC49_RS16060 2e8f26501c79197b1bde0fcd95235bf5 209 Pfam PF00072 Response regulator receiver domain 6 117 2.3E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS16060 2e8f26501c79197b1bde0fcd95235bf5 209 SUPERFAMILY SSF52172 4 135 9.82E-24 T 29-03-2018 IPR011006 CheY-like superfamily MC49_RS16060 2e8f26501c79197b1bde0fcd95235bf5 209 SMART SM00448 4 117 3.1E-14 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS16060 2e8f26501c79197b1bde0fcd95235bf5 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 1.9E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS16060 2e8f26501c79197b1bde0fcd95235bf5 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 1.9E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS16060 2e8f26501c79197b1bde0fcd95235bf5 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 1.9E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS16060 2e8f26501c79197b1bde0fcd95235bf5 209 SMART SM00421 145 202 3.8E-20 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS16060 2e8f26501c79197b1bde0fcd95235bf5 209 SUPERFAMILY SSF46894 129 207 1.05E-20 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MC49_RS10155 8b2f318695b0c99ec7534a822ebe9016 860 Pfam PF08264 Anticodon-binding domain of tRNA 700 823 6.3E-16 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 MC49_RS10155 8b2f318695b0c99ec7534a822ebe9016 860 SUPERFAMILY SSF47323 662 859 4.86E-35 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS10155 8b2f318695b0c99ec7534a822ebe9016 860 PRINTS PR00985 Leucyl-tRNA synthetase signature 557 567 5.4E-52 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MC49_RS10155 8b2f318695b0c99ec7534a822ebe9016 860 PRINTS PR00985 Leucyl-tRNA synthetase signature 215 234 5.4E-52 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MC49_RS10155 8b2f318695b0c99ec7534a822ebe9016 860 PRINTS PR00985 Leucyl-tRNA synthetase signature 524 546 5.4E-52 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MC49_RS10155 8b2f318695b0c99ec7534a822ebe9016 860 PRINTS PR00985 Leucyl-tRNA synthetase signature 485 503 5.4E-52 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MC49_RS10155 8b2f318695b0c99ec7534a822ebe9016 860 PRINTS PR00985 Leucyl-tRNA synthetase signature 127 144 5.4E-52 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MC49_RS10155 8b2f318695b0c99ec7534a822ebe9016 860 PRINTS PR00985 Leucyl-tRNA synthetase signature 185 198 5.4E-52 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MC49_RS10155 8b2f318695b0c99ec7534a822ebe9016 860 PRINTS PR00985 Leucyl-tRNA synthetase signature 153 169 5.4E-52 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MC49_RS10155 8b2f318695b0c99ec7534a822ebe9016 860 Gene3D G3DSA:3.40.50.620 416 647 5.4E-58 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS10155 8b2f318695b0c99ec7534a822ebe9016 860 Gene3D G3DSA:1.10.730.10 648 797 1.3E-30 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS10155 8b2f318695b0c99ec7534a822ebe9016 860 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 53 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS10155 8b2f318695b0c99ec7534a822ebe9016 860 Gene3D G3DSA:3.90.740.10 158 415 5.7E-62 T 29-03-2018 MC49_RS10155 8b2f318695b0c99ec7534a822ebe9016 860 Gene3D G3DSA:3.40.50.620 32 157 2.5E-49 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS10155 8b2f318695b0c99ec7534a822ebe9016 860 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 221 403 1.2E-78 T 29-03-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 MC49_RS10155 8b2f318695b0c99ec7534a822ebe9016 860 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 4 859 23.4 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MC49_RS10155 8b2f318695b0c99ec7534a822ebe9016 860 SUPERFAMILY SSF50677 226 415 3.24E-57 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MC49_RS10155 8b2f318695b0c99ec7534a822ebe9016 860 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 14 171 2.0E-26 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS10155 8b2f318695b0c99ec7534a822ebe9016 860 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 417 572 1.2E-6 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS10155 8b2f318695b0c99ec7534a822ebe9016 860 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 618 650 8.9E-7 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS10155 8b2f318695b0c99ec7534a822ebe9016 860 SUPERFAMILY SSF52374 416 668 1.1E-141 T 29-03-2018 MC49_RS10155 8b2f318695b0c99ec7534a822ebe9016 860 SUPERFAMILY SSF52374 5 226 1.1E-141 T 29-03-2018 MC49_RS10155 8b2f318695b0c99ec7534a822ebe9016 860 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 5 859 0.0 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MC49_RS04945 ee2e7cfe2d32342cd8781b6e579f437e 810 SMART SM00487 164 359 5.2E-20 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MC49_RS04945 ee2e7cfe2d32342cd8781b6e579f437e 810 Pfam PF00271 Helicase conserved C-terminal domain 410 525 9.5E-8 T 29-03-2018 IPR001650 Helicase, C-terminal MC49_RS04945 ee2e7cfe2d32342cd8781b6e579f437e 810 SUPERFAMILY SSF52540 146 363 2.7E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS04945 ee2e7cfe2d32342cd8781b6e579f437e 810 Pfam PF04851 Type III restriction enzyme, res subunit 167 324 6.6E-42 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MC49_RS04945 ee2e7cfe2d32342cd8781b6e579f437e 810 Gene3D G3DSA:3.40.50.300 133 346 5.4E-25 T 29-03-2018 MC49_RS04945 ee2e7cfe2d32342cd8781b6e579f437e 810 SUPERFAMILY SSF52540 187 224 2.13E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS04945 ee2e7cfe2d32342cd8781b6e579f437e 810 SUPERFAMILY SSF52540 278 283 2.13E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS04945 ee2e7cfe2d32342cd8781b6e579f437e 810 SUPERFAMILY SSF52540 394 527 2.13E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS04945 ee2e7cfe2d32342cd8781b6e579f437e 810 Pfam PF13588 Type I restriction enzyme R protein N terminus (HSDR_N) 34 122 4.4E-9 T 29-03-2018 IPR029464 Type I restriction enzyme R protein, N-terminal domain MC49_RS04945 ee2e7cfe2d32342cd8781b6e579f437e 810 Pfam PF08463 EcoEI R protein C-terminal 646 803 1.7E-24 T 29-03-2018 IPR013670 EcoEI R protein C-terminal domain GO:0003677|GO:0003824|GO:0006304 MC49_RS04945 ee2e7cfe2d32342cd8781b6e579f437e 810 Gene3D G3DSA:3.40.50.300 397 546 4.5E-10 T 29-03-2018 MC49_RS07400 b0b7e0d52c8a20982879e8023fec9629 572 Gene3D G3DSA:3.20.20.140 147 426 1.6E-142 T 29-03-2018 MC49_RS07400 b0b7e0d52c8a20982879e8023fec9629 572 Gene3D G3DSA:3.20.20.140 427 558 2.7E-47 T 29-03-2018 MC49_RS07400 b0b7e0d52c8a20982879e8023fec9629 572 Pfam PF00449 Urease alpha-subunit, N-terminal domain 3 124 7.0E-49 T 29-03-2018 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MC49_RS07400 b0b7e0d52c8a20982879e8023fec9629 572 Hamap MF_01953 Urease subunit alpha [ureC]. 2 572 53.231 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MC49_RS07400 b0b7e0d52c8a20982879e8023fec9629 572 Gene3D G3DSA:2.30.40.10 67 146 7.5E-13 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS07400 b0b7e0d52c8a20982879e8023fec9629 572 ProSitePatterns PS01120 Urease nickel ligands signature. 132 145 - T 29-03-2018 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MC49_RS07400 b0b7e0d52c8a20982879e8023fec9629 572 SUPERFAMILY SSF51556 486 571 4.63E-179 T 29-03-2018 IPR032466 Metal-dependent hydrolase MC49_RS07400 b0b7e0d52c8a20982879e8023fec9629 572 SUPERFAMILY SSF51556 135 437 4.63E-179 T 29-03-2018 IPR032466 Metal-dependent hydrolase MC49_RS07400 b0b7e0d52c8a20982879e8023fec9629 572 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 3 571 2.4E-280 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MC49_RS07400 b0b7e0d52c8a20982879e8023fec9629 572 Pfam PF01979 Amidohydrolase family 130 459 2.1E-73 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MC49_RS07400 b0b7e0d52c8a20982879e8023fec9629 572 ProSitePatterns PS00145 Urease active site. 322 338 - T 29-03-2018 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MC49_RS07400 b0b7e0d52c8a20982879e8023fec9629 572 SUPERFAMILY SSF51338 2 183 5.19E-55 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS07400 b0b7e0d52c8a20982879e8023fec9629 572 SUPERFAMILY SSF51338 414 484 8.31E-10 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS07400 b0b7e0d52c8a20982879e8023fec9629 572 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 432 445 4.4E-27 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MC49_RS07400 b0b7e0d52c8a20982879e8023fec9629 572 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 406 421 4.4E-27 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MC49_RS07400 b0b7e0d52c8a20982879e8023fec9629 572 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 300 317 4.4E-27 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MC49_RS07400 b0b7e0d52c8a20982879e8023fec9629 572 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 339 355 4.4E-27 T 29-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MC49_RS01890 953581427914f1163fe3debc929e5198 279 Pfam PF05675 Protein of unknown function (DUF817) 26 262 7.3E-101 T 29-03-2018 IPR008535 Protein of unknown function DUF817 MC49_RS01890 953581427914f1163fe3debc929e5198 279 PIRSF PIRSF009141 15 279 2.1E-118 T 29-03-2018 IPR008535 Protein of unknown function DUF817 MC49_RS18515 2099feaaf007f6d56c3450b00b92a5db 286 Gene3D G3DSA:2.30.30.60 131 179 7.5E-12 T 29-03-2018 MC49_RS18515 2099feaaf007f6d56c3450b00b92a5db 286 SUPERFAMILY SSF82689 181 279 1.16E-32 T 29-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 MC49_RS18515 2099feaaf007f6d56c3450b00b92a5db 286 Pfam PF05552 Conserved TM helix 16 64 1.6E-12 T 29-03-2018 IPR008910 Conserved TM helix MC49_RS18515 2099feaaf007f6d56c3450b00b92a5db 286 Pfam PF00924 Mechanosensitive ion channel 72 268 8.8E-54 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MC49_RS18515 2099feaaf007f6d56c3450b00b92a5db 286 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 143 177 - T 29-03-2018 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 MC49_RS18515 2099feaaf007f6d56c3450b00b92a5db 286 SUPERFAMILY SSF50182 114 179 1.37E-14 T 29-03-2018 IPR010920 LSM domain MC49_RS18515 2099feaaf007f6d56c3450b00b92a5db 286 SUPERFAMILY SSF82861 28 112 2.22E-16 T 29-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 MC49_RS18515 2099feaaf007f6d56c3450b00b92a5db 286 Gene3D G3DSA:3.30.70.100 180 273 2.1E-27 T 29-03-2018 MC49_RS15585 7028da3cec40307d7f9b3bafe1387c81 78 Pfam PF09584 Phage shock protein PspD (Phageshock_PspD) 15 68 2.2E-9 T 29-03-2018 IPR014321 Phage shock protein, PspD MC49_RS02715 ef436fb75a00c68edf4feefe486e5be6 88 Pfam PF01313 Bacterial export proteins, family 3 3 74 4.1E-24 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 MC49_RS02715 ef436fb75a00c68edf4feefe486e5be6 88 PIRSF PIRSF004669 1 85 5.2E-22 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 MC49_RS02715 ef436fb75a00c68edf4feefe486e5be6 88 TIGRFAM TIGR01403 fliQ_rel_III: type III secretion protein, HrpO family 4 79 3.3E-26 T 29-03-2018 IPR006306 Type III secretion protein HrpO GO:0006810|GO:0016021 MC49_RS02715 ef436fb75a00c68edf4feefe486e5be6 88 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 51 73 5.7E-23 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 MC49_RS02715 ef436fb75a00c68edf4feefe486e5be6 88 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 15 36 5.7E-23 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 MC49_RS02715 ef436fb75a00c68edf4feefe486e5be6 88 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 36 51 5.7E-23 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 MC49_RS19085 4544c3a0a1efd2c2387cb878d688fd09 440 Gene3D G3DSA:3.20.20.70 4 294 9.0E-70 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS19085 4544c3a0a1efd2c2387cb878d688fd09 440 PIRSF PIRSF009264 1 429 7.0E-200 T 29-03-2018 IPR012062 D-tagatose-bisphosphate aldolase, non-catalytic subunit GatZ/KbaZ GO:0019402 MC49_RS19085 4544c3a0a1efd2c2387cb878d688fd09 440 Pfam PF08013 Tagatose 6 phosphate kinase 4 424 2.8E-201 T 29-03-2018 IPR012062 D-tagatose-bisphosphate aldolase, non-catalytic subunit GatZ/KbaZ GO:0019402 MC49_RS19085 4544c3a0a1efd2c2387cb878d688fd09 440 SUPERFAMILY SSF51569 4 424 1.79E-169 T 29-03-2018 MC49_RS19085 4544c3a0a1efd2c2387cb878d688fd09 440 Gene3D G3DSA:1.10.400.20 295 408 1.8E-46 T 29-03-2018 MC49_RS19085 4544c3a0a1efd2c2387cb878d688fd09 440 TIGRFAM TIGR02810 agaZ_gatZ: D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit 6 424 7.4E-206 T 29-03-2018 IPR012062 D-tagatose-bisphosphate aldolase, non-catalytic subunit GatZ/KbaZ GO:0019402 MC49_RS12975 1de855bbeb796ac5c720570c796b9d68 142 Gene3D G3DSA:3.40.50.620 1 142 2.3E-23 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS12975 1de855bbeb796ac5c720570c796b9d68 142 PRINTS PR01438 Universal stress protein signature 120 142 1.3E-11 T 29-03-2018 IPR006015 Universal stress protein A MC49_RS12975 1de855bbeb796ac5c720570c796b9d68 142 PRINTS PR01438 Universal stress protein signature 103 115 1.3E-11 T 29-03-2018 IPR006015 Universal stress protein A MC49_RS12975 1de855bbeb796ac5c720570c796b9d68 142 PRINTS PR01438 Universal stress protein signature 2 20 1.3E-11 T 29-03-2018 IPR006015 Universal stress protein A MC49_RS12975 1de855bbeb796ac5c720570c796b9d68 142 Pfam PF00582 Universal stress protein family 1 142 1.9E-21 T 29-03-2018 IPR006016 UspA GO:0006950 MC49_RS12975 1de855bbeb796ac5c720570c796b9d68 142 SUPERFAMILY SSF52402 2 142 6.28E-26 T 29-03-2018 MC49_RS00640 fd75b5496ed8b1ff199bcd03f908c634 117 SUPERFAMILY SSF75169 1 117 6.54E-32 T 29-03-2018 IPR027396 DsrEFH-like MC49_RS00640 fd75b5496ed8b1ff199bcd03f908c634 117 Pfam PF02635 DsrE/DsrF-like family 4 117 1.2E-21 T 29-03-2018 IPR003787 Sulphur relay, DsrE/F-like protein MC49_RS00640 fd75b5496ed8b1ff199bcd03f908c634 117 Gene3D G3DSA:3.40.1260.10 1 117 2.1E-28 T 29-03-2018 MC49_RS15030 81df39442eb3853b97b8d42aeaa99147 780 Pfam PF13375 RnfC Barrel sandwich hybrid domain 14 114 2.2E-32 T 29-03-2018 IPR026902 RnfC Barrel sandwich hybrid domain MC49_RS15030 81df39442eb3853b97b8d42aeaa99147 780 Pfam PF10531 SLBB domain 296 344 4.1E-12 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS15030 81df39442eb3853b97b8d42aeaa99147 780 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 139 283 6.6E-48 T 29-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS15030 81df39442eb3853b97b8d42aeaa99147 780 Gene3D G3DSA:3.30.70.20 323 383 0.0027 T 29-03-2018 MC49_RS15030 81df39442eb3853b97b8d42aeaa99147 780 Gene3D G3DSA:3.30.70.20 384 485 1.4E-16 T 29-03-2018 MC49_RS15030 81df39442eb3853b97b8d42aeaa99147 780 Pfam PF12838 4Fe-4S dicluster domain 376 430 1.6E-8 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MC49_RS15030 81df39442eb3853b97b8d42aeaa99147 780 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 416 427 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MC49_RS15030 81df39442eb3853b97b8d42aeaa99147 780 SUPERFAMILY SSF142019 94 303 7.85E-58 T 29-03-2018 MC49_RS15030 81df39442eb3853b97b8d42aeaa99147 780 Hamap MF_00461 Electron transport complex subunit RsxC [rsxC]. 1 744 253.394 T 29-03-2018 IPR010208 Electron transport complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 MC49_RS15030 81df39442eb3853b97b8d42aeaa99147 780 TIGRFAM TIGR01945 rnfC: electron transport complex, RnfABCDGE type, C subunit 13 445 6.2E-181 T 29-03-2018 IPR010208 Electron transport complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 MC49_RS15030 81df39442eb3853b97b8d42aeaa99147 780 SUPERFAMILY SSF46548 336 443 2.27E-19 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MC49_RS11010 6df9cae2a8f2e264e000fc2753195c67 560 Gene3D G3DSA:3.40.50.300 1 351 1.4E-16 T 29-03-2018 MC49_RS11010 6df9cae2a8f2e264e000fc2753195c67 560 SUPERFAMILY SSF52540 1 353 4.32E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS11010 6df9cae2a8f2e264e000fc2753195c67 560 Pfam PF11398 Protein of unknown function (DUF2813) 1 383 5.3E-133 T 29-03-2018 IPR022602 Protein of unknown function DUF2813 MC49_RS13875 1b93c1c696ac1380411795fd657f0c41 359 TIGRFAM TIGR04112 seleno_YedE: putative selenium metabolism protein, YedE family 8 342 7.1E-140 T 29-03-2018 IPR026366 Putative selenium metabolism protein, YedE family MC49_RS00775 013a04901446f3b40fb84ee7bc184f3b 252 Pfam PF03502 Nucleoside-specific channel-forming protein, Tsx 32 252 1.9E-44 T 29-03-2018 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 MC49_RS00775 013a04901446f3b40fb84ee7bc184f3b 252 SUPERFAMILY SSF111364 24 252 1.44E-32 T 29-03-2018 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 MC49_RS00775 013a04901446f3b40fb84ee7bc184f3b 252 Gene3D G3DSA:2.40.230.20 17 247 4.7E-29 T 29-03-2018 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 MC49_RS11125 ab2fd73754d80f0e68fa23948c109d19 229 SUPERFAMILY SSF52540 6 224 5.77E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS11125 ab2fd73754d80f0e68fa23948c109d19 229 Hamap MF_00238 Cytidylate kinase [cmk]. 6 224 33.351 T 29-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 MC49_RS11125 ab2fd73754d80f0e68fa23948c109d19 229 TIGRFAM TIGR00017 cmk: cytidylate kinase 6 218 6.3E-87 T 29-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 MC49_RS11125 ab2fd73754d80f0e68fa23948c109d19 229 Gene3D G3DSA:3.40.50.300 4 224 4.2E-49 T 29-03-2018 MC49_RS11125 ab2fd73754d80f0e68fa23948c109d19 229 Pfam PF02224 Cytidylate kinase 8 221 5.9E-80 T 29-03-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 MC49_RS11730 3fd7de2f0bf0824aa8cf514c1406b0da 531 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 109 527 5.0E-137 T 29-03-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 MC49_RS11730 3fd7de2f0bf0824aa8cf514c1406b0da 531 SMART SM00858 11 82 5.9E-12 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 MC49_RS11730 3fd7de2f0bf0824aa8cf514c1406b0da 531 Pfam PF08666 SAF domain 11 82 3.0E-11 T 29-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 MC49_RS15500 190382e039200a4f9f8f990666e73683 406 SUPERFAMILY SSF103473 4 388 9.29E-55 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS15500 190382e039200a4f9f8f990666e73683 406 Pfam PF07690 Major Facilitator Superfamily 18 294 4.6E-30 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS15500 190382e039200a4f9f8f990666e73683 406 Gene3D G3DSA:1.20.1250.20 1 198 7.3E-26 T 29-03-2018 MC49_RS15500 190382e039200a4f9f8f990666e73683 406 Gene3D G3DSA:1.20.1250.20 199 387 1.2E-15 T 29-03-2018 MC49_RS03020 776bec1a72d4ddb6aaf3c81c6bcb2362 244 ProSitePatterns PS00635 Gram-negative pili assembly chaperone signature. 101 118 - T 29-03-2018 IPR018046 Pili assembly chaperone, conserved site MC49_RS03020 776bec1a72d4ddb6aaf3c81c6bcb2362 244 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 169 225 4.5E-12 T 29-03-2018 IPR016148 Pili assembly chaperone, C-terminal MC49_RS03020 776bec1a72d4ddb6aaf3c81c6bcb2362 244 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 26 143 1.4E-37 T 29-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 MC49_RS03020 776bec1a72d4ddb6aaf3c81c6bcb2362 244 Gene3D G3DSA:2.60.40.10 25 144 2.6E-34 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS03020 776bec1a72d4ddb6aaf3c81c6bcb2362 244 Gene3D G3DSA:2.60.40.10 148 243 2.2E-19 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS03020 776bec1a72d4ddb6aaf3c81c6bcb2362 244 SUPERFAMILY SSF49584 156 239 1.07E-16 T 29-03-2018 IPR016148 Pili assembly chaperone, C-terminal MC49_RS03020 776bec1a72d4ddb6aaf3c81c6bcb2362 244 SUPERFAMILY SSF49354 26 144 2.07E-36 T 29-03-2018 IPR008962 PapD-like MC49_RS03020 776bec1a72d4ddb6aaf3c81c6bcb2362 244 PRINTS PR00969 Pili chaperone signature 72 93 1.0E-32 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS03020 776bec1a72d4ddb6aaf3c81c6bcb2362 244 PRINTS PR00969 Pili chaperone signature 102 119 1.0E-32 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS03020 776bec1a72d4ddb6aaf3c81c6bcb2362 244 PRINTS PR00969 Pili chaperone signature 164 179 1.0E-32 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS03020 776bec1a72d4ddb6aaf3c81c6bcb2362 244 PRINTS PR00969 Pili chaperone signature 125 140 1.0E-32 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS03020 776bec1a72d4ddb6aaf3c81c6bcb2362 244 PRINTS PR00969 Pili chaperone signature 26 35 1.0E-32 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS18095 4cb012fe7224484c39c8d4e83c89896e 456 Pfam PF01212 Beta-eliminating lyase 46 422 4.5E-99 T 29-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 MC49_RS18095 4cb012fe7224484c39c8d4e83c89896e 456 Gene3D G3DSA:3.90.1150.10 17 150 6.8E-33 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS18095 4cb012fe7224484c39c8d4e83c89896e 456 Gene3D G3DSA:3.90.1150.10 273 454 9.7E-74 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS18095 4cb012fe7224484c39c8d4e83c89896e 456 SUPERFAMILY SSF53383 3 455 2.54E-139 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS18095 4cb012fe7224484c39c8d4e83c89896e 456 TIGRFAM TIGR02618 tyr_phenol_ly: tyrosine phenol-lyase 5 454 4.9E-285 T 29-03-2018 IPR013441 Tyrosine phenol-lyase GO:0006570|GO:0050371 KEGG: 00350+4.1.99.2 MC49_RS18095 4cb012fe7224484c39c8d4e83c89896e 456 PIRSF PIRSF001386 1 456 2.0E-213 T 29-03-2018 IPR011166 Beta-eliminating lyase family GO:0009072|GO:0016830 KEGG: 00380+4.1.99.1 MC49_RS18095 4cb012fe7224484c39c8d4e83c89896e 456 ProSitePatterns PS00853 Beta-eliminating lyases pyridoxal-phosphate attachment site. 247 265 - T 29-03-2018 IPR018176 Tryptophanase, conserved site KEGG: 00380+4.1.99.1 MC49_RS18095 4cb012fe7224484c39c8d4e83c89896e 456 Hamap MF_00543 Tyrosine phenol-lyase [tpl]. 1 456 79.662 T 29-03-2018 IPR013441 Tyrosine phenol-lyase GO:0006570|GO:0050371 KEGG: 00350+4.1.99.2 MC49_RS12545 ebb334feb3ff4cfad30f916386c7e8ab 249 PRINTS PR01008 Flagellar L-ring protein signature 226 240 2.3E-33 T 29-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 MC49_RS12545 ebb334feb3ff4cfad30f916386c7e8ab 249 PRINTS PR01008 Flagellar L-ring protein signature 189 205 2.3E-33 T 29-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 MC49_RS12545 ebb334feb3ff4cfad30f916386c7e8ab 249 PRINTS PR01008 Flagellar L-ring protein signature 210 224 2.3E-33 T 29-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 MC49_RS12545 ebb334feb3ff4cfad30f916386c7e8ab 249 PRINTS PR01008 Flagellar L-ring protein signature 163 178 2.3E-33 T 29-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 MC49_RS12545 ebb334feb3ff4cfad30f916386c7e8ab 249 PRINTS PR01008 Flagellar L-ring protein signature 90 102 2.3E-33 T 29-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 MC49_RS12545 ebb334feb3ff4cfad30f916386c7e8ab 249 Pfam PF02107 Flagellar L-ring protein 63 248 2.7E-59 T 29-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 MC49_RS12545 ebb334feb3ff4cfad30f916386c7e8ab 249 Hamap MF_00415 Flagellar L-ring protein [flgH]. 21 247 26.969 T 29-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 MC49_RS07495 ff274e84dcdfc8c72037971c874d73b8 178 Pfam PF01931 Protein of unknown function DUF84 7 165 5.1E-53 T 29-03-2018 IPR026533 Non-canonical purine NTP phosphatase/PRRC1 MC49_RS07495 ff274e84dcdfc8c72037971c874d73b8 178 Gene3D G3DSA:3.90.950.10 1 170 1.1E-55 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MC49_RS07495 ff274e84dcdfc8c72037971c874d73b8 178 Hamap MF_00648 Non-canonical purine NTP phosphatase. 2 171 29.428 T 29-03-2018 IPR002786 Non-canonical purine NTP phosphatase MC49_RS07495 ff274e84dcdfc8c72037971c874d73b8 178 TIGRFAM TIGR00258 TIGR00258: inosine/xanthosine triphosphatase 7 170 6.1E-49 T 29-03-2018 IPR002786 Non-canonical purine NTP phosphatase MC49_RS07495 ff274e84dcdfc8c72037971c874d73b8 178 SUPERFAMILY SSF52972 1 167 3.88E-57 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MC49_RS10565 c6c3bf8698bcdc3e959a23b4dbfa2e45 329 SUPERFAMILY SSF50974 74 325 3.14E-43 T 29-03-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 MC49_RS10565 c6c3bf8698bcdc3e959a23b4dbfa2e45 329 SUPERFAMILY SSF50974 4 69 2.09E-7 T 29-03-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 MC49_RS10565 c6c3bf8698bcdc3e959a23b4dbfa2e45 329 Pfam PF10282 Lactonase, 7-bladed beta-propeller 6 324 1.4E-81 T 29-03-2018 IPR019405 Lactonase, 7-bladed beta propeller MC49_RS10565 c6c3bf8698bcdc3e959a23b4dbfa2e45 329 Gene3D G3DSA:2.130.10.10 2 113 1.0E-15 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MC49_RS10565 c6c3bf8698bcdc3e959a23b4dbfa2e45 329 Gene3D G3DSA:2.130.10.10 114 328 2.1E-27 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MC49_RS09755 cbb8aaffd94caf1c8aca282c18f0e9fe 351 Hamap MF_01113 DNA polymerase IV [dinB]. 1 349 36.748 T 29-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 MC49_RS09755 cbb8aaffd94caf1c8aca282c18f0e9fe 351 Pfam PF00817 impB/mucB/samB family 7 154 9.4E-48 T 29-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MC49_RS09755 cbb8aaffd94caf1c8aca282c18f0e9fe 351 Pfam PF11799 impB/mucB/samB family C-terminal domain 236 337 2.0E-7 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MC49_RS09755 cbb8aaffd94caf1c8aca282c18f0e9fe 351 SUPERFAMILY SSF100879 241 350 6.28E-25 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MC49_RS09755 cbb8aaffd94caf1c8aca282c18f0e9fe 351 SUPERFAMILY SSF56672 1 234 2.31E-90 T 29-03-2018 MC49_RS09755 cbb8aaffd94caf1c8aca282c18f0e9fe 351 Gene3D G3DSA:1.10.150.20 171 242 7.7E-21 T 29-03-2018 MC49_RS09755 cbb8aaffd94caf1c8aca282c18f0e9fe 351 Gene3D G3DSA:3.30.1490.100 243 351 9.5E-27 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MC49_RS09755 cbb8aaffd94caf1c8aca282c18f0e9fe 351 Gene3D G3DSA:3.30.70.270 116 170 5.0E-20 T 29-03-2018 MC49_RS09755 cbb8aaffd94caf1c8aca282c18f0e9fe 351 Gene3D G3DSA:3.30.70.270 41 115 7.1E-23 T 29-03-2018 MC49_RS09755 cbb8aaffd94caf1c8aca282c18f0e9fe 351 Pfam PF11798 IMS family HHH motif 171 197 3.0E-6 T 29-03-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 MC49_RS14790 91c58d78f4d14d9f7d3e6c94681b1292 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 59 3.0E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS14790 91c58d78f4d14d9f7d3e6c94681b1292 204 SUPERFAMILY SSF48498 85 189 1.5E-11 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MC49_RS14790 91c58d78f4d14d9f7d3e6c94681b1292 204 Gene3D G3DSA:1.10.10.60 1 60 4.6E-13 T 29-03-2018 MC49_RS14790 91c58d78f4d14d9f7d3e6c94681b1292 204 SUPERFAMILY SSF46689 5 82 3.13E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS14790 91c58d78f4d14d9f7d3e6c94681b1292 204 Gene3D G3DSA:1.10.357.10 61 196 6.8E-14 T 29-03-2018 MC49_RS11180 06e1cde1af96961bef3673bccd6386d3 441 SUPERFAMILY SSF46785 8 118 8.3E-47 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS11180 06e1cde1af96961bef3673bccd6386d3 441 PIRSF PIRSF018282 1 441 2.3E-244 T 29-03-2018 IPR005582 Chromosome partition protein MukF GO:0005509|GO:0006260|GO:0007059 MC49_RS11180 06e1cde1af96961bef3673bccd6386d3 441 Pfam PF03882 MukF winged-helix domain 3 117 2.8E-54 T 29-03-2018 IPR033439 Chromosome partition protein MukF, winged-helix domain MC49_RS11180 06e1cde1af96961bef3673bccd6386d3 441 Gene3D G3DSA:1.10.10.10 24 116 4.8E-37 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS11180 06e1cde1af96961bef3673bccd6386d3 441 Hamap MF_01803 Chromosome partition protein MukF [mukF]. 1 441 53.897 T 29-03-2018 IPR005582 Chromosome partition protein MukF GO:0005509|GO:0006260|GO:0007059 MC49_RS11180 06e1cde1af96961bef3673bccd6386d3 441 Pfam PF17193 MukF C-terminal domain 284 441 1.1E-78 T 29-03-2018 IPR033441 Chromosome partition protein MukF, C-terminal domain MC49_RS11180 06e1cde1af96961bef3673bccd6386d3 441 Pfam PF17192 MukF middle domain 121 282 6.7E-82 T 29-03-2018 IPR033440 Chromosome partition protein MukF, middle domain MC49_RS11180 06e1cde1af96961bef3673bccd6386d3 441 SUPERFAMILY SSF140570 119 282 7.45E-71 T 29-03-2018 IPR033440 Chromosome partition protein MukF, middle domain MC49_RS10130 f5040042b6efec92eb9e53eafc8743a8 119 SUPERFAMILY SSF46785 13 110 8.24E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS10130 f5040042b6efec92eb9e53eafc8743a8 119 Gene3D G3DSA:1.10.10.10 18 114 1.1E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS10130 f5040042b6efec92eb9e53eafc8743a8 119 Pfam PF01638 HxlR-like helix-turn-helix 20 108 8.8E-28 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type MC49_RS13145 0f22cfb5eddcc8b49c8ffae4465c86c0 1044 Gene3D G3DSA:2.60.40.10 598 694 0.0031 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS13145 0f22cfb5eddcc8b49c8ffae4465c86c0 1044 Gene3D G3DSA:2.60.40.10 695 792 0.0049 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS13145 0f22cfb5eddcc8b49c8ffae4465c86c0 1044 Pfam PF13550 Putative phage tail protein 330 493 4.4E-30 T 29-03-2018 IPR032876 Tip attachment protein J MC49_RS13145 0f22cfb5eddcc8b49c8ffae4465c86c0 1044 Pfam PF09327 Domain of unknown function (DUF1983) 898 968 1.3E-15 T 29-03-2018 IPR015406 Domain of unknown function DUF1983 MC49_RS07650 f1471dc72d67e1497bf045e6f28a53a0 274 PRINTS PR00069 Aldo-keto reductase signature 91 109 1.2E-45 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MC49_RS07650 f1471dc72d67e1497bf045e6f28a53a0 274 PRINTS PR00069 Aldo-keto reductase signature 37 61 1.2E-45 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MC49_RS07650 f1471dc72d67e1497bf045e6f28a53a0 274 PRINTS PR00069 Aldo-keto reductase signature 123 140 1.2E-45 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MC49_RS07650 f1471dc72d67e1497bf045e6f28a53a0 274 PRINTS PR00069 Aldo-keto reductase signature 157 186 1.2E-45 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MC49_RS07650 f1471dc72d67e1497bf045e6f28a53a0 274 PRINTS PR00069 Aldo-keto reductase signature 196 220 1.2E-45 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MC49_RS07650 f1471dc72d67e1497bf045e6f28a53a0 274 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 41 58 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MC49_RS07650 f1471dc72d67e1497bf045e6f28a53a0 274 SUPERFAMILY SSF51430 7 267 7.2E-89 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MC49_RS07650 f1471dc72d67e1497bf045e6f28a53a0 274 PIRSF PIRSF000097 110 270 8.2E-51 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MC49_RS07650 f1471dc72d67e1497bf045e6f28a53a0 274 PIRSF PIRSF000097 1 117 2.8E-44 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MC49_RS07650 f1471dc72d67e1497bf045e6f28a53a0 274 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 229 244 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MC49_RS07650 f1471dc72d67e1497bf045e6f28a53a0 274 Gene3D G3DSA:3.20.20.100 2 274 1.6E-92 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MC49_RS07650 f1471dc72d67e1497bf045e6f28a53a0 274 Pfam PF00248 Aldo/keto reductase family 18 260 9.1E-49 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain MC49_RS07650 f1471dc72d67e1497bf045e6f28a53a0 274 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 123 140 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MC49_RS00590 69166d42a9a8aa5a20c3051898919bdb 318 Gene3D G3DSA:3.40.50.1400 2 173 2.8E-47 T 29-03-2018 MC49_RS00590 69166d42a9a8aa5a20c3051898919bdb 318 ProSitePatterns PS00534 Ferrochelatase signature. 190 210 - T 29-03-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 MC49_RS00590 69166d42a9a8aa5a20c3051898919bdb 318 TIGRFAM TIGR00109 hemH: ferrochelatase 3 317 1.7E-102 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 MC49_RS00590 69166d42a9a8aa5a20c3051898919bdb 318 Pfam PF00762 Ferrochelatase 6 317 7.2E-104 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 MC49_RS00590 69166d42a9a8aa5a20c3051898919bdb 318 Gene3D G3DSA:3.40.50.1400 174 302 1.1E-41 T 29-03-2018 MC49_RS00590 69166d42a9a8aa5a20c3051898919bdb 318 Hamap MF_00323 Ferrochelatase [hemH]. 5 318 33.69 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 MC49_RS00590 69166d42a9a8aa5a20c3051898919bdb 318 SUPERFAMILY SSF53800 5 317 5.63E-100 T 29-03-2018 MC49_RS18740 14a54bbb8bdcb6d1fe4a9ca59d69806b 470 ProSitePatterns PS01244 Aconitase family signature 2. 401 414 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MC49_RS18740 14a54bbb8bdcb6d1fe4a9ca59d69806b 470 Pfam PF00330 Aconitase family (aconitate hydratase) 10 459 3.1E-161 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS18740 14a54bbb8bdcb6d1fe4a9ca59d69806b 470 PRINTS PR00415 Aconitase family signature 197 210 5.8E-50 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS18740 14a54bbb8bdcb6d1fe4a9ca59d69806b 470 PRINTS PR00415 Aconitase family signature 84 97 5.8E-50 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS18740 14a54bbb8bdcb6d1fe4a9ca59d69806b 470 PRINTS PR00415 Aconitase family signature 110 118 5.8E-50 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS18740 14a54bbb8bdcb6d1fe4a9ca59d69806b 470 PRINTS PR00415 Aconitase family signature 135 150 5.8E-50 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS18740 14a54bbb8bdcb6d1fe4a9ca59d69806b 470 PRINTS PR00415 Aconitase family signature 345 356 5.8E-50 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS18740 14a54bbb8bdcb6d1fe4a9ca59d69806b 470 PRINTS PR00415 Aconitase family signature 288 302 5.8E-50 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS18740 14a54bbb8bdcb6d1fe4a9ca59d69806b 470 PRINTS PR00415 Aconitase family signature 211 224 5.8E-50 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS18740 14a54bbb8bdcb6d1fe4a9ca59d69806b 470 PRINTS PR00415 Aconitase family signature 121 134 5.8E-50 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS18740 14a54bbb8bdcb6d1fe4a9ca59d69806b 470 PRINTS PR00415 Aconitase family signature 401 414 5.8E-50 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS18740 14a54bbb8bdcb6d1fe4a9ca59d69806b 470 ProSitePatterns PS00450 Aconitase family signature 1. 341 357 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MC49_RS18740 14a54bbb8bdcb6d1fe4a9ca59d69806b 470 Gene3D G3DSA:3.30.499.10 327 470 7.2E-54 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS18740 14a54bbb8bdcb6d1fe4a9ca59d69806b 470 Gene3D G3DSA:3.40.1060.10 156 290 2.5E-44 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS18740 14a54bbb8bdcb6d1fe4a9ca59d69806b 470 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 4 467 1.3E-265 T 29-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 MC49_RS18740 14a54bbb8bdcb6d1fe4a9ca59d69806b 470 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 3 468 61.597 T 29-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 MC49_RS18740 14a54bbb8bdcb6d1fe4a9ca59d69806b 470 Gene3D G3DSA:3.30.499.10 1 155 2.0E-41 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS18740 14a54bbb8bdcb6d1fe4a9ca59d69806b 470 SUPERFAMILY SSF53732 4 468 2.88E-170 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS12740 185d9b54f26e22a13b5bf1c9c510d012 329 SUPERFAMILY SSF53448 6 218 5.27E-62 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MC49_RS12740 185d9b54f26e22a13b5bf1c9c510d012 329 Pfam PF00535 Glycosyl transferase family 2 8 125 3.0E-37 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MC49_RS12740 185d9b54f26e22a13b5bf1c9c510d012 329 Gene3D G3DSA:3.90.550.10 5 221 9.9E-55 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MC49_RS11995 2087cf89fb594127ad4982a18fc55207 258 Hamap MF_01974 Methionine aminopeptidase [map]. 4 252 37.403 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MC49_RS11995 2087cf89fb594127ad4982a18fc55207 258 Pfam PF00557 Metallopeptidase family M24 13 243 4.5E-49 T 29-03-2018 IPR000994 Peptidase M24 MC49_RS11995 2087cf89fb594127ad4982a18fc55207 258 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 4 251 1.4E-89 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MC49_RS11995 2087cf89fb594127ad4982a18fc55207 258 Gene3D G3DSA:3.90.230.10 2 258 8.4E-79 T 29-03-2018 MC49_RS11995 2087cf89fb594127ad4982a18fc55207 258 PRINTS PR00599 Methionine aminopeptidase-1 signature 194 206 1.8E-20 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MC49_RS11995 2087cf89fb594127ad4982a18fc55207 258 PRINTS PR00599 Methionine aminopeptidase-1 signature 163 175 1.8E-20 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MC49_RS11995 2087cf89fb594127ad4982a18fc55207 258 PRINTS PR00599 Methionine aminopeptidase-1 signature 70 83 1.8E-20 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MC49_RS11995 2087cf89fb594127ad4982a18fc55207 258 PRINTS PR00599 Methionine aminopeptidase-1 signature 93 109 1.8E-20 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MC49_RS11995 2087cf89fb594127ad4982a18fc55207 258 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 169 187 - T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MC49_RS11995 2087cf89fb594127ad4982a18fc55207 258 SUPERFAMILY SSF55920 4 254 8.37E-84 T 29-03-2018 IPR000994 Peptidase M24 MC49_RS00915 be6e015a9ca8360097863cbf53826eef 431 SUPERFAMILY SSF55874 259 423 3.14E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS00915 be6e015a9ca8360097863cbf53826eef 431 Gene3D G3DSA:1.10.287.130 209 265 4.1E-18 T 29-03-2018 MC49_RS00915 be6e015a9ca8360097863cbf53826eef 431 Pfam PF00512 His Kinase A (phospho-acceptor) domain 203 267 5.8E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS00915 be6e015a9ca8360097863cbf53826eef 431 SMART SM00388 203 269 1.6E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS00915 be6e015a9ca8360097863cbf53826eef 431 SUPERFAMILY SSF55785 87 195 1.92E-10 T 29-03-2018 IPR000014 PAS domain MC49_RS00915 be6e015a9ca8360097863cbf53826eef 431 Pfam PF11808 Domain of unknown function (DUF3329) 6 91 5.7E-28 T 29-03-2018 IPR021766 Protein of unknown function DUF3329 GO:0004673 MC49_RS00915 be6e015a9ca8360097863cbf53826eef 431 TIGRFAM TIGR02966 phoR_proteo: phosphate regulon sensor kinase PhoR 95 421 6.4E-133 T 29-03-2018 IPR014310 Signal transduction histidine kinase, phosphate regulon sensor PhoR GO:0000155|GO:0000160|GO:0004673|GO:0016021 MC49_RS00915 be6e015a9ca8360097863cbf53826eef 431 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 313 423 2.7E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS00915 be6e015a9ca8360097863cbf53826eef 431 Pfam PF00989 PAS fold 99 152 1.7E-7 T 29-03-2018 IPR013767 PAS fold GO:0006355 MC49_RS00915 be6e015a9ca8360097863cbf53826eef 431 SMART SM00387 313 425 2.4E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS00915 be6e015a9ca8360097863cbf53826eef 431 Gene3D G3DSA:3.30.450.20 97 208 7.0E-15 T 29-03-2018 MC49_RS00915 be6e015a9ca8360097863cbf53826eef 431 SMART SM00091 98 165 4.4E-5 T 29-03-2018 IPR000014 PAS domain MC49_RS00915 be6e015a9ca8360097863cbf53826eef 431 Gene3D G3DSA:3.30.565.10 288 431 4.8E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS00915 be6e015a9ca8360097863cbf53826eef 431 PRINTS PR00344 Bacterial sensor protein C-terminal signature 368 378 5.9E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS00915 be6e015a9ca8360097863cbf53826eef 431 PRINTS PR00344 Bacterial sensor protein C-terminal signature 350 364 5.9E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS00915 be6e015a9ca8360097863cbf53826eef 431 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 403 5.9E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS00915 be6e015a9ca8360097863cbf53826eef 431 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 422 5.9E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS00915 be6e015a9ca8360097863cbf53826eef 431 SUPERFAMILY SSF47384 190 267 4.12E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS15465 5cf88e154995ea520ed2f8005567f033 432 Gene3D G3DSA:3.50.50.60 2 423 2.6E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS15465 5cf88e154995ea520ed2f8005567f033 432 SUPERFAMILY SSF54373 269 359 6.02E-14 T 29-03-2018 MC49_RS15465 5cf88e154995ea520ed2f8005567f033 432 SUPERFAMILY SSF51905 107 271 1.04E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS15465 5cf88e154995ea520ed2f8005567f033 432 SUPERFAMILY SSF51905 1 54 1.04E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS15465 5cf88e154995ea520ed2f8005567f033 432 SUPERFAMILY SSF51905 359 427 1.04E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS15465 5cf88e154995ea520ed2f8005567f033 432 Pfam PF01266 FAD dependent oxidoreductase 3 397 1.5E-70 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MC49_RS15465 5cf88e154995ea520ed2f8005567f033 432 Hamap MF_01202 D-amino acid dehydrogenase [dadA]. 1 410 49.199 T 29-03-2018 IPR023080 D-amino acid dehydrogenase DadA GO:0008718|GO:0019478|GO:0055114 MC49_RS05890 fc84caa5d84b88b3bf359d812ddc073f 105 ProDom PD020365 REPRESSOR MET BIOSYNTHESIS TRANSCRIPTION METJ METHIONINE REGULON DNA-BINDING REGULATORY AMINO-ACID 10 101 7.0E-46 T 29-03-2018 IPR002084 Methionine repressor MetJ GO:0003700|GO:0006355|GO:0006555 MC49_RS05890 fc84caa5d84b88b3bf359d812ddc073f 105 Hamap MF_00744 Met repressor [metJ]. 1 105 40.655 T 29-03-2018 IPR002084 Methionine repressor MetJ GO:0003700|GO:0006355|GO:0006555 MC49_RS05890 fc84caa5d84b88b3bf359d812ddc073f 105 SUPERFAMILY SSF47598 2 105 1.27E-57 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 MC49_RS05890 fc84caa5d84b88b3bf359d812ddc073f 105 Gene3D G3DSA:1.10.140.10 3 103 4.9E-59 T 29-03-2018 IPR023453 Methionine repressor MetJ domain MC49_RS05890 fc84caa5d84b88b3bf359d812ddc073f 105 Pfam PF01340 Met Apo-repressor, MetJ 3 99 1.6E-58 T 29-03-2018 IPR002084 Methionine repressor MetJ GO:0003700|GO:0006355|GO:0006555 MC49_RS06990 1ed6e8743ad9d26541ce21bd7d229aa2 359 Gene3D G3DSA:3.20.20.10 10 201 9.3E-41 T 29-03-2018 IPR029066 PLP-binding barrel MC49_RS06990 1ed6e8743ad9d26541ce21bd7d229aa2 359 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 31 41 - T 29-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MC49_RS06990 1ed6e8743ad9d26541ce21bd7d229aa2 359 Pfam PF00842 Alanine racemase, C-terminal domain 233 356 2.0E-40 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MC49_RS06990 1ed6e8743ad9d26541ce21bd7d229aa2 359 SUPERFAMILY SSF51419 8 234 1.74E-68 T 29-03-2018 IPR029066 PLP-binding barrel MC49_RS06990 1ed6e8743ad9d26541ce21bd7d229aa2 359 PRINTS PR00992 Alanine racemase signature 339 352 2.3E-70 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MC49_RS06990 1ed6e8743ad9d26541ce21bd7d229aa2 359 PRINTS PR00992 Alanine racemase signature 266 281 2.3E-70 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MC49_RS06990 1ed6e8743ad9d26541ce21bd7d229aa2 359 PRINTS PR00992 Alanine racemase signature 26 42 2.3E-70 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MC49_RS06990 1ed6e8743ad9d26541ce21bd7d229aa2 359 PRINTS PR00992 Alanine racemase signature 60 78 2.3E-70 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MC49_RS06990 1ed6e8743ad9d26541ce21bd7d229aa2 359 PRINTS PR00992 Alanine racemase signature 120 132 2.3E-70 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MC49_RS06990 1ed6e8743ad9d26541ce21bd7d229aa2 359 PRINTS PR00992 Alanine racemase signature 192 219 2.3E-70 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MC49_RS06990 1ed6e8743ad9d26541ce21bd7d229aa2 359 PRINTS PR00992 Alanine racemase signature 287 304 2.3E-70 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MC49_RS06990 1ed6e8743ad9d26541ce21bd7d229aa2 359 PRINTS PR00992 Alanine racemase signature 155 166 2.3E-70 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MC49_RS06990 1ed6e8743ad9d26541ce21bd7d229aa2 359 PRINTS PR00992 Alanine racemase signature 249 264 2.3E-70 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MC49_RS06990 1ed6e8743ad9d26541ce21bd7d229aa2 359 Gene3D G3DSA:2.40.37.10 202 359 5.3E-59 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MC49_RS06990 1ed6e8743ad9d26541ce21bd7d229aa2 359 SUPERFAMILY SSF50621 227 358 8.72E-46 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MC49_RS06990 1ed6e8743ad9d26541ce21bd7d229aa2 359 Hamap MF_01201 Alanine racemase. 1 357 34.872 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MC49_RS06990 1ed6e8743ad9d26541ce21bd7d229aa2 359 Pfam PF01168 Alanine racemase, N-terminal domain 8 219 1.8E-68 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MC49_RS06990 1ed6e8743ad9d26541ce21bd7d229aa2 359 TIGRFAM TIGR00492 alr: alanine racemase 3 358 1.0E-132 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MC49_RS06990 1ed6e8743ad9d26541ce21bd7d229aa2 359 SMART SM01005 233 357 8.9E-63 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MC49_RS17315 71c3def4bbc2a1188325584e4ad65a9a 408 Pfam PF11922 Domain of unknown function (DUF3440) 357 389 5.1E-8 T 29-03-2018 IPR021845 Protein of unknown function DUF3440 MC49_RS17315 71c3def4bbc2a1188325584e4ad65a9a 408 Pfam PF11922 Domain of unknown function (DUF3440) 239 342 1.4E-26 T 29-03-2018 IPR021845 Protein of unknown function DUF3440 MC49_RS17315 71c3def4bbc2a1188325584e4ad65a9a 408 SUPERFAMILY SSF52402 11 234 1.58E-34 T 29-03-2018 MC49_RS17315 71c3def4bbc2a1188325584e4ad65a9a 408 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 31 233 9.1E-14 T 29-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 MC49_RS17315 71c3def4bbc2a1188325584e4ad65a9a 408 Gene3D G3DSA:3.40.50.620 10 235 2.4E-22 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS11025 c1575812a31a5e51ff253e5a6fe5dbe2 76 PRINTS PR00050 Cold shock protein signature 4 19 9.5E-16 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MC49_RS11025 c1575812a31a5e51ff253e5a6fe5dbe2 76 PRINTS PR00050 Cold shock protein signature 40 58 9.5E-16 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MC49_RS11025 c1575812a31a5e51ff253e5a6fe5dbe2 76 PRINTS PR00050 Cold shock protein signature 25 34 9.5E-16 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MC49_RS11025 c1575812a31a5e51ff253e5a6fe5dbe2 76 TIGRFAM TIGR02381 cspD: cold shock domain protein CspD 1 67 1.3E-37 T 29-03-2018 IPR012751 CspD, cold shock GO:0003676|GO:0005737|GO:0006355|GO:0006950 MC49_RS11025 c1575812a31a5e51ff253e5a6fe5dbe2 76 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 29-03-2018 IPR019844 Cold-shock conserved site MC49_RS11025 c1575812a31a5e51ff253e5a6fe5dbe2 76 Gene3D G3DSA:2.40.50.140 1 65 2.6E-24 T 29-03-2018 MC49_RS11025 c1575812a31a5e51ff253e5a6fe5dbe2 76 PIRSF PIRSF002599 1 74 2.3E-21 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 MC49_RS11025 c1575812a31a5e51ff253e5a6fe5dbe2 76 SMART SM00357 3 67 3.2E-25 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 MC49_RS11025 c1575812a31a5e51ff253e5a6fe5dbe2 76 Pfam PF00313 'Cold-shock' DNA-binding domain 3 60 1.8E-27 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MC49_RS11025 c1575812a31a5e51ff253e5a6fe5dbe2 76 SUPERFAMILY SSF50249 1 62 9.52E-23 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS09925 922b205e3e6d6820dfa70225599cb966 244 Gene3D G3DSA:1.25.20.10 30 244 4.8E-15 T 29-03-2018 MC49_RS09925 922b205e3e6d6820dfa70225599cb966 244 Pfam PF13525 Outer membrane lipoprotein 28 236 3.3E-79 T 29-03-2018 MC49_RS09925 922b205e3e6d6820dfa70225599cb966 244 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 5 241 1.8E-82 T 29-03-2018 IPR017689 Outer membrane protein assembly factor BamD MC49_RS09925 922b205e3e6d6820dfa70225599cb966 244 Hamap MF_00922 Outer membrane protein assembly factor BamD [bamD]. 4 242 37.834 T 29-03-2018 IPR017689 Outer membrane protein assembly factor BamD MC49_RS09925 922b205e3e6d6820dfa70225599cb966 244 SUPERFAMILY SSF48452 30 120 3.84E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MC49_RS04275 aef2926bc3272440ee5c7802707bfa6d 210 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 197 3.7E-40 T 29-03-2018 IPR002751 Cobalamin (vitamin B12) biosynthesis CbiM family GO:0000041|GO:0016021 MC49_RS01795 87f8fb5835bdf0be52572ccb202d31a4 233 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS01795 87f8fb5835bdf0be52572ccb202d31a4 233 PIRSF PIRSF039137 1 233 1.0E-101 T 29-03-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 MC49_RS01795 87f8fb5835bdf0be52572ccb202d31a4 233 SUPERFAMILY SSF52540 2 225 3.22E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS01795 87f8fb5835bdf0be52572ccb202d31a4 233 Gene3D G3DSA:3.40.50.300 1 233 1.4E-58 T 29-03-2018 MC49_RS01795 87f8fb5835bdf0be52572ccb202d31a4 233 Pfam PF00005 ABC transporter 17 161 1.6E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS01795 87f8fb5835bdf0be52572ccb202d31a4 233 SMART SM00382 26 212 0.0028 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS04675 8176c2999cf4608c7953af3add075e23 342 SUPERFAMILY SSF52374 12 337 9.52E-94 T 29-03-2018 MC49_RS04675 8176c2999cf4608c7953af3add075e23 342 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 19 28 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS04675 8176c2999cf4608c7953af3add075e23 342 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 10 338 40.781 T 29-03-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 MC49_RS04675 8176c2999cf4608c7953af3add075e23 342 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 149 170 2.0E-26 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MC49_RS04675 8176c2999cf4608c7953af3add075e23 342 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 23 39 2.0E-26 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MC49_RS04675 8176c2999cf4608c7953af3add075e23 342 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 202 212 2.0E-26 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MC49_RS04675 8176c2999cf4608c7953af3add075e23 342 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 73 92 2.0E-26 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MC49_RS04675 8176c2999cf4608c7953af3add075e23 342 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 10 337 3.1E-111 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MC49_RS04675 8176c2999cf4608c7953af3add075e23 342 Pfam PF00579 tRNA synthetases class I (W and Y) 9 292 2.1E-80 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS04675 8176c2999cf4608c7953af3add075e23 342 Gene3D G3DSA:3.40.50.620 9 208 1.4E-71 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS04675 8176c2999cf4608c7953af3add075e23 342 Gene3D G3DSA:1.10.240.10 209 320 1.7E-30 T 29-03-2018 MC49_RS01705 a32e558d4b9af2f55ee86057fc9a8ef4 323 Pfam PF01207 Dihydrouridine synthase (Dus) 14 318 1.6E-113 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MC49_RS01705 a32e558d4b9af2f55ee86057fc9a8ef4 323 Hamap MF_02042 tRNA-dihydrouridine synthase B [dusB]. 1 321 48.869 T 29-03-2018 IPR032887 tRNA-dihydrouridine synthase B GO:0002943|GO:0017150 MC49_RS01705 a32e558d4b9af2f55ee86057fc9a8ef4 323 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 94 112 - T 29-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 MC49_RS01705 a32e558d4b9af2f55ee86057fc9a8ef4 323 Gene3D G3DSA:3.20.20.70 6 246 1.7E-54 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS01705 a32e558d4b9af2f55ee86057fc9a8ef4 323 PIRSF PIRSF006621 1 322 4.3E-100 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MC49_RS01705 a32e558d4b9af2f55ee86057fc9a8ef4 323 Gene3D G3DSA:1.10.1200.80 252 323 6.4E-21 T 29-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 MC49_RS01705 a32e558d4b9af2f55ee86057fc9a8ef4 323 SUPERFAMILY SSF51395 10 319 7.14E-86 T 29-03-2018 MC49_RS01705 a32e558d4b9af2f55ee86057fc9a8ef4 323 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 3 319 5.0E-137 T 29-03-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 MC49_RS05095 a89225f8f8f5fffed58d39dad94c5399 139 SUPERFAMILY SSF102546 1 139 2.09E-41 T 29-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 MC49_RS05095 a89225f8f8f5fffed58d39dad94c5399 139 Gene3D G3DSA:3.40.1650.10 1 139 3.9E-37 T 29-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 MC49_RS05095 a89225f8f8f5fffed58d39dad94c5399 139 Hamap MF_01661 D-ribose pyranase [rbsD]. 1 139 31.535 T 29-03-2018 IPR023064 D-ribose pyranase GO:0016872 MC49_RS05095 a89225f8f8f5fffed58d39dad94c5399 139 Pfam PF05025 RbsD / FucU transport protein family 1 138 5.6E-44 T 29-03-2018 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 MC49_RS01685 18c8ea095df6220ebae3c6e4231899e7 152 SUPERFAMILY SSF52304 6 148 7.59E-63 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MC49_RS01685 18c8ea095df6220ebae3c6e4231899e7 152 ProSitePatterns PS01029 Dehydroquinase class II signature. 10 27 - T 29-03-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MC49_RS01685 18c8ea095df6220ebae3c6e4231899e7 152 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 20 150 2.0E-56 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MC49_RS01685 18c8ea095df6220ebae3c6e4231899e7 152 Pfam PF01220 Dehydroquinase class II 7 142 1.9E-61 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MC49_RS01685 18c8ea095df6220ebae3c6e4231899e7 152 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 6 144 2.1E-61 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MC49_RS01685 18c8ea095df6220ebae3c6e4231899e7 152 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 152 74.569 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MC49_RS01685 18c8ea095df6220ebae3c6e4231899e7 152 Gene3D G3DSA:3.40.50.9100 2 149 4.3E-68 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MC49_RS01685 18c8ea095df6220ebae3c6e4231899e7 152 PIRSF PIRSF001399 3 149 2.8E-59 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MC49_RS01305 601ab8d876688167d03396e4397a63f1 164 Pfam PF01750 Hydrogenase maturation protease 20 147 1.3E-35 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MC49_RS01305 601ab8d876688167d03396e4397a63f1 164 TIGRFAM TIGR00140 hupD: hydrogenase expression/formation protein 3 153 1.7E-51 T 29-03-2018 IPR004419 Peptidase A31, hydrogenase expression/formation protein GO:0016485|GO:0046872 MC49_RS01305 601ab8d876688167d03396e4397a63f1 164 PRINTS PR00446 Hydrogen uptake protein signature 68 84 5.2E-23 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MC49_RS01305 601ab8d876688167d03396e4397a63f1 164 PRINTS PR00446 Hydrogen uptake protein signature 3 15 5.2E-23 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MC49_RS01305 601ab8d876688167d03396e4397a63f1 164 PRINTS PR00446 Hydrogen uptake protein signature 56 66 5.2E-23 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MC49_RS01305 601ab8d876688167d03396e4397a63f1 164 PRINTS PR00446 Hydrogen uptake protein signature 35 52 5.2E-23 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MC49_RS01305 601ab8d876688167d03396e4397a63f1 164 PRINTS PR00446 Hydrogen uptake protein signature 15 26 5.2E-23 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MC49_RS01305 601ab8d876688167d03396e4397a63f1 164 SUPERFAMILY SSF53163 1 158 7.19E-47 T 29-03-2018 IPR023430 Peptidase HybD-like domain MC49_RS01305 601ab8d876688167d03396e4397a63f1 164 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 4 148 1.1E-46 T 29-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MC49_RS01305 601ab8d876688167d03396e4397a63f1 164 Gene3D G3DSA:3.40.50.1450 1 162 1.3E-55 T 29-03-2018 IPR023430 Peptidase HybD-like domain MC49_RS18690 9959e1fa29c8742f432111cb3e9acea1 313 Pfam PF01795 MraW methylase family 6 312 5.9E-114 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MC49_RS18690 9959e1fa29c8742f432111cb3e9acea1 313 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 4 312 1.5E-124 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MC49_RS18690 9959e1fa29c8742f432111cb3e9acea1 313 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 8 313 38.439 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MC49_RS18690 9959e1fa29c8742f432111cb3e9acea1 313 SUPERFAMILY SSF81799 115 215 5.36E-34 T 29-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MC49_RS18690 9959e1fa29c8742f432111cb3e9acea1 313 SUPERFAMILY SSF53335 215 312 4.84E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS18690 9959e1fa29c8742f432111cb3e9acea1 313 SUPERFAMILY SSF53335 8 114 4.84E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS18690 9959e1fa29c8742f432111cb3e9acea1 313 PIRSF PIRSF004486 2 313 9.0E-101 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MC49_RS18690 9959e1fa29c8742f432111cb3e9acea1 313 Gene3D G3DSA:3.40.50.150 2 91 4.8E-6 T 29-03-2018 MC49_RS18690 9959e1fa29c8742f432111cb3e9acea1 313 Gene3D G3DSA:1.10.150.170 113 217 3.6E-37 T 29-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MC49_RS07060 86777a868d1b24dbca7f6c603c7d1d96 320 Gene3D G3DSA:3.40.190.10 177 264 5.1E-18 T 29-03-2018 MC49_RS07060 86777a868d1b24dbca7f6c603c7d1d96 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 7.6E-15 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS07060 86777a868d1b24dbca7f6c603c7d1d96 320 Gene3D G3DSA:1.10.10.10 1 84 3.3E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS07060 86777a868d1b24dbca7f6c603c7d1d96 320 SUPERFAMILY SSF46785 2 109 5.03E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS07060 86777a868d1b24dbca7f6c603c7d1d96 320 SUPERFAMILY SSF53850 91 291 1.32E-38 T 29-03-2018 MC49_RS07060 86777a868d1b24dbca7f6c603c7d1d96 320 Pfam PF03466 LysR substrate binding domain 91 290 1.2E-41 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS07060 86777a868d1b24dbca7f6c603c7d1d96 320 Gene3D G3DSA:3.40.190.10 88 176 1.3E-17 T 29-03-2018 MC49_RS07285 cff80422b2ddd6193f680db2319a55e5 151 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 12 142 1.8E-41 T 29-03-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 MC49_RS07285 cff80422b2ddd6193f680db2319a55e5 151 SUPERFAMILY SSF55729 1 146 5.57E-35 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS07285 cff80422b2ddd6193f680db2319a55e5 151 Gene3D G3DSA:3.40.630.30 1 148 3.4E-36 T 29-03-2018 MC49_RS07285 cff80422b2ddd6193f680db2319a55e5 151 Pfam PF00583 Acetyltransferase (GNAT) family 28 120 5.8E-19 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MC49_RS05415 e04a793d7f290395622c0380c9413416 195 Pfam PF00384 Molybdopterin oxidoreductase 107 139 3.1E-6 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS05415 e04a793d7f290395622c0380c9413416 195 Gene3D G3DSA:3.40.50.740 109 195 5.5E-13 T 29-03-2018 MC49_RS05415 e04a793d7f290395622c0380c9413416 195 Gene3D G3DSA:2.20.25.90 37 108 1.2E-20 T 29-03-2018 MC49_RS05415 e04a793d7f290395622c0380c9413416 195 SUPERFAMILY SSF53706 36 195 1.09E-55 T 29-03-2018 MC49_RS05415 e04a793d7f290395622c0380c9413416 195 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 44 103 1.1E-19 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS05415 e04a793d7f290395622c0380c9413416 195 SMART SM00926 43 104 1.9E-22 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS05415 e04a793d7f290395622c0380c9413416 195 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 48 66 - T 29-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 MC49_RS12435 38872c5d674c796426830bc21ebfb52f 690 SUPERFAMILY SSF47226 3 123 1.7E-31 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MC49_RS12435 38872c5d674c796426830bc21ebfb52f 690 Pfam PF09078 CheY binding 171 230 4.4E-20 T 29-03-2018 IPR015162 CheY binding MC49_RS12435 38872c5d674c796426830bc21ebfb52f 690 SMART SM01231 290 353 3.3E-19 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 MC49_RS12435 38872c5d674c796426830bc21ebfb52f 690 Gene3D G3DSA:2.30.30.40 616 669 1.6E-21 T 29-03-2018 MC49_RS12435 38872c5d674c796426830bc21ebfb52f 690 Gene3D G3DSA:3.30.70.400 167 232 6.2E-22 T 29-03-2018 IPR015162 CheY binding MC49_RS12435 38872c5d674c796426830bc21ebfb52f 690 SMART SM00387 398 538 1.3E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS12435 38872c5d674c796426830bc21ebfb52f 690 Gene3D G3DSA:2.40.50.180 562 615 1.2E-7 T 29-03-2018 MC49_RS12435 38872c5d674c796426830bc21ebfb52f 690 Gene3D G3DSA:3.30.565.10 355 539 1.1E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS12435 38872c5d674c796426830bc21ebfb52f 690 Gene3D G3DSA:1.20.120.160 1 148 1.7E-30 T 29-03-2018 MC49_RS12435 38872c5d674c796426830bc21ebfb52f 690 SUPERFAMILY SSF55052 168 232 1.78E-16 T 29-03-2018 IPR015162 CheY binding MC49_RS12435 38872c5d674c796426830bc21ebfb52f 690 SMART SM00260 530 670 4.0E-36 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MC49_RS12435 38872c5d674c796426830bc21ebfb52f 690 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 401 537 4.6E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS12435 38872c5d674c796426830bc21ebfb52f 690 PRINTS PR00344 Bacterial sensor protein C-terminal signature 522 535 7.8E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS12435 38872c5d674c796426830bc21ebfb52f 690 PRINTS PR00344 Bacterial sensor protein C-terminal signature 443 457 7.8E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS12435 38872c5d674c796426830bc21ebfb52f 690 PRINTS PR00344 Bacterial sensor protein C-terminal signature 498 516 7.8E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS12435 38872c5d674c796426830bc21ebfb52f 690 Gene3D G3DSA:1.10.287.560 290 354 5.3E-19 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 MC49_RS12435 38872c5d674c796426830bc21ebfb52f 690 Pfam PF01584 CheW-like domain 543 669 9.3E-24 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MC49_RS12435 38872c5d674c796426830bc21ebfb52f 690 SUPERFAMILY SSF50341 537 669 6.28E-29 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 MC49_RS12435 38872c5d674c796426830bc21ebfb52f 690 SUPERFAMILY SSF47384 292 354 5.1E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS12435 38872c5d674c796426830bc21ebfb52f 690 SMART SM00073 3 100 9.6E-33 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MC49_RS12435 38872c5d674c796426830bc21ebfb52f 690 Pfam PF01627 Hpt domain 5 95 9.1E-20 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 MC49_RS12435 38872c5d674c796426830bc21ebfb52f 690 SUPERFAMILY SSF55874 352 540 9.95E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS12435 38872c5d674c796426830bc21ebfb52f 690 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 292 353 1.1E-16 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 MC49_RS08440 3fddb736c5295a035f30432e559271cf 385 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 24 374 30.393 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 MC49_RS08440 3fddb736c5295a035f30432e559271cf 385 TIGRFAM TIGR00312 cbiD: cobalamin biosynthesis protein CbiD 31 374 2.5E-83 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 MC49_RS08440 3fddb736c5295a035f30432e559271cf 385 Gene3D G3DSA:3.30.2110.10 26 195 1.6E-55 T 29-03-2018 MC49_RS08440 3fddb736c5295a035f30432e559271cf 385 SUPERFAMILY SSF111342 16 298 1.44E-84 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 MC49_RS08440 3fddb736c5295a035f30432e559271cf 385 PIRSF PIRSF026782 20 380 3.0E-126 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 MC49_RS08440 3fddb736c5295a035f30432e559271cf 385 Pfam PF01888 CbiD 24 280 1.2E-92 T 29-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 MC49_RS00060 a7027961b20b0c2fee4bbdb316aeacc3 232 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 67 90 1.0E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS00060 a7027961b20b0c2fee4bbdb316aeacc3 232 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 59 1.0E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS00060 a7027961b20b0c2fee4bbdb316aeacc3 232 SUPERFAMILY SSF46689 39 110 3.85E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS00060 a7027961b20b0c2fee4bbdb316aeacc3 232 Gene3D G3DSA:1.10.10.60 13 94 5.1E-11 T 29-03-2018 MC49_RS00060 a7027961b20b0c2fee4bbdb316aeacc3 232 SUPERFAMILY SSF48498 114 227 6.47E-23 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MC49_RS00060 a7027961b20b0c2fee4bbdb316aeacc3 232 Pfam PF00440 Bacterial regulatory proteins, tetR family 47 88 9.3E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS00060 a7027961b20b0c2fee4bbdb316aeacc3 232 Gene3D G3DSA:1.10.357.10 95 228 1.7E-18 T 29-03-2018 MC49_RS00060 a7027961b20b0c2fee4bbdb316aeacc3 232 Pfam PF16925 Bacterial transcriptional repressor C-terminal 114 227 3.6E-46 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MC49_RS11305 4e925ceafeb4042a20f95456d51859f6 177 Pfam PF17414 MatP C-terminal ribbon-helix-helix domain 113 172 3.8E-30 T 29-03-2018 IPR035375 MatP, C-terminal ribbon-helix-helix domain MC49_RS11305 4e925ceafeb4042a20f95456d51859f6 177 Gene3D G3DSA:1.10.3990.20 104 164 2.3E-4 T 29-03-2018 MC49_RS11305 4e925ceafeb4042a20f95456d51859f6 177 Hamap MF_01073 Macrodomain Ter protein [matP]. 26 173 29.542 T 29-03-2018 IPR009390 Macrodomain Ter protein, MatP GO:0043565 MC49_RS11305 4e925ceafeb4042a20f95456d51859f6 177 ProDom PD033720 UPF0268 YCBG DEHYDROGENASE PM0482 PBPRA1775 PLU1774 YPO1433/Y2737/YP0877 VV1664 HI1323 HD0178 26 156 6.0E-56 T 29-03-2018 IPR009390 Macrodomain Ter protein, MatP GO:0043565 MC49_RS11305 4e925ceafeb4042a20f95456d51859f6 177 Pfam PF06303 MatP N-terminal domain 27 110 2.3E-44 T 29-03-2018 IPR035087 MatP, N-terminal MC49_RS06140 ff0a08ab1e0666c19e8d06c4f9ffd1e0 327 Gene3D G3DSA:3.40.50.300 1 323 1.1E-70 T 29-03-2018 MC49_RS06140 ff0a08ab1e0666c19e8d06c4f9ffd1e0 327 SUPERFAMILY SSF52540 3 253 3.15E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS06140 ff0a08ab1e0666c19e8d06c4f9ffd1e0 327 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 231 315 3.3E-24 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MC49_RS06140 ff0a08ab1e0666c19e8d06c4f9ffd1e0 327 Pfam PF00005 ABC transporter 24 181 2.4E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS06140 ff0a08ab1e0666c19e8d06c4f9ffd1e0 327 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 297 2.1E-17 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MC49_RS06140 ff0a08ab1e0666c19e8d06c4f9ffd1e0 327 SMART SM00382 32 231 1.6E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS06140 ff0a08ab1e0666c19e8d06c4f9ffd1e0 327 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS01635 ee55bc5ff3a99fcd501406bfc98284fb 98 SUPERFAMILY SSF52038 6 86 7.85E-21 T 29-03-2018 IPR000468 Barstar (barnase inhibitor) MC49_RS01635 ee55bc5ff3a99fcd501406bfc98284fb 98 Gene3D G3DSA:3.30.370.10 5 91 4.9E-22 T 29-03-2018 IPR000468 Barstar (barnase inhibitor) MC49_RS01635 ee55bc5ff3a99fcd501406bfc98284fb 98 Pfam PF01337 Barstar (barnase inhibitor) 10 83 5.1E-15 T 29-03-2018 IPR000468 Barstar (barnase inhibitor) MC49_RS07630 3f28c2c539233e65ae1a25a816629859 271 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 4 267 35.035 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MC49_RS07630 3f28c2c539233e65ae1a25a816629859 271 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 5 127 9.8E-41 T 29-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MC49_RS07630 3f28c2c539233e65ae1a25a816629859 271 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 4 267 1.3E-108 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MC49_RS07630 3f28c2c539233e65ae1a25a816629859 271 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 152 169 - T 29-03-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MC49_RS07630 3f28c2c539233e65ae1a25a816629859 271 Gene3D G3DSA:3.30.360.10 128 236 2.1E-34 T 29-03-2018 MC49_RS07630 3f28c2c539233e65ae1a25a816629859 271 PIRSF PIRSF000161 2 270 4.9E-90 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MC49_RS07630 3f28c2c539233e65ae1a25a816629859 271 Gene3D G3DSA:3.40.50.720 1 123 6.7E-27 T 29-03-2018 MC49_RS07630 3f28c2c539233e65ae1a25a816629859 271 SUPERFAMILY SSF55347 129 238 6.98E-37 T 29-03-2018 MC49_RS07630 3f28c2c539233e65ae1a25a816629859 271 SUPERFAMILY SSF51735 4 128 9.56E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS07630 3f28c2c539233e65ae1a25a816629859 271 SUPERFAMILY SSF51735 238 269 9.56E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS07630 3f28c2c539233e65ae1a25a816629859 271 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 130 266 3.1E-44 T 29-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MC49_RS15460 9bad8784e2579a0d95c842e6204c8566 356 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 32 42 - T 29-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MC49_RS15460 9bad8784e2579a0d95c842e6204c8566 356 SUPERFAMILY SSF50621 225 353 3.84E-49 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MC49_RS15460 9bad8784e2579a0d95c842e6204c8566 356 SUPERFAMILY SSF51419 9 232 2.43E-57 T 29-03-2018 IPR029066 PLP-binding barrel MC49_RS15460 9bad8784e2579a0d95c842e6204c8566 356 SMART SM01005 231 355 3.3E-72 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MC49_RS15460 9bad8784e2579a0d95c842e6204c8566 356 Pfam PF01168 Alanine racemase, N-terminal domain 9 216 1.3E-59 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MC49_RS15460 9bad8784e2579a0d95c842e6204c8566 356 TIGRFAM TIGR00492 alr: alanine racemase 4 353 2.1E-109 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MC49_RS15460 9bad8784e2579a0d95c842e6204c8566 356 Gene3D G3DSA:3.20.20.10 5 200 1.2E-31 T 29-03-2018 IPR029066 PLP-binding barrel MC49_RS15460 9bad8784e2579a0d95c842e6204c8566 356 Hamap MF_01201 Alanine racemase. 2 355 33.209 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MC49_RS15460 9bad8784e2579a0d95c842e6204c8566 356 PRINTS PR00992 Alanine racemase signature 337 350 7.5E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MC49_RS15460 9bad8784e2579a0d95c842e6204c8566 356 PRINTS PR00992 Alanine racemase signature 61 79 7.5E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MC49_RS15460 9bad8784e2579a0d95c842e6204c8566 356 PRINTS PR00992 Alanine racemase signature 285 302 7.5E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MC49_RS15460 9bad8784e2579a0d95c842e6204c8566 356 PRINTS PR00992 Alanine racemase signature 155 166 7.5E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MC49_RS15460 9bad8784e2579a0d95c842e6204c8566 356 PRINTS PR00992 Alanine racemase signature 27 43 7.5E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MC49_RS15460 9bad8784e2579a0d95c842e6204c8566 356 PRINTS PR00992 Alanine racemase signature 264 279 7.5E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MC49_RS15460 9bad8784e2579a0d95c842e6204c8566 356 PRINTS PR00992 Alanine racemase signature 121 133 7.5E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MC49_RS15460 9bad8784e2579a0d95c842e6204c8566 356 PRINTS PR00992 Alanine racemase signature 189 216 7.5E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MC49_RS15460 9bad8784e2579a0d95c842e6204c8566 356 PRINTS PR00992 Alanine racemase signature 247 262 7.5E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MC49_RS15460 9bad8784e2579a0d95c842e6204c8566 356 Gene3D G3DSA:2.40.37.10 201 356 2.6E-63 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MC49_RS15460 9bad8784e2579a0d95c842e6204c8566 356 Pfam PF00842 Alanine racemase, C-terminal domain 231 352 1.4E-44 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MC49_RS13635 f7bfb5d356c6e3ebd45237d4abcdcc63 322 Gene3D G3DSA:3.40.50.510 1 143 1.4E-32 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 MC49_RS13635 f7bfb5d356c6e3ebd45237d4abcdcc63 322 TIGRFAM TIGR00854 pts-sorbose: PTS system, mannose/fructose/sorbose family, IIB component 163 310 1.3E-54 T 29-03-2018 IPR018455 Phosphotransferase system, sorbose subfamily IIB component, subgroup GO:0005737|GO:0008982|GO:0009401 MC49_RS13635 f7bfb5d356c6e3ebd45237d4abcdcc63 322 Pfam PF03610 PTS system fructose IIA component 2 118 3.6E-29 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 MC49_RS13635 f7bfb5d356c6e3ebd45237d4abcdcc63 322 Pfam PF03830 PTS system sorbose subfamily IIB component 163 310 3.0E-54 T 29-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 MC49_RS13635 f7bfb5d356c6e3ebd45237d4abcdcc63 322 Gene3D G3DSA:3.40.35.10 162 318 4.0E-59 T 29-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 MC49_RS13635 f7bfb5d356c6e3ebd45237d4abcdcc63 322 TIGRFAM TIGR00824 EIIA-man: PTS system, mannose/fructose/sorbose family, IIA component 1 118 4.8E-37 T 29-03-2018 IPR013789 Phosphotransferase system, mannose family IIA component GO:0005737|GO:0008643|GO:0016773 MC49_RS13635 f7bfb5d356c6e3ebd45237d4abcdcc63 322 SUPERFAMILY SSF53062 2 130 1.83E-32 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 MC49_RS13635 f7bfb5d356c6e3ebd45237d4abcdcc63 322 SUPERFAMILY SSF52728 161 320 1.27E-54 T 29-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 MC49_RS02065 f2ed1d53738e0ab2707a3316bbb56b45 206 SUPERFAMILY SSF54862 1 101 1.17E-41 T 29-03-2018 MC49_RS02065 f2ed1d53738e0ab2707a3316bbb56b45 206 SUPERFAMILY SSF54862 140 185 1.17E-41 T 29-03-2018 MC49_RS02065 f2ed1d53738e0ab2707a3316bbb56b45 206 Pfam PF00037 4Fe-4S binding domain 75 98 3.8E-8 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MC49_RS02065 f2ed1d53738e0ab2707a3316bbb56b45 206 Gene3D G3DSA:3.30.70.20 19 63 2.8E-9 T 29-03-2018 MC49_RS02065 f2ed1d53738e0ab2707a3316bbb56b45 206 Gene3D G3DSA:3.30.70.20 155 192 0.0014 T 29-03-2018 MC49_RS02065 f2ed1d53738e0ab2707a3316bbb56b45 206 Gene3D G3DSA:3.30.70.20 1 18 0.0034 T 29-03-2018 MC49_RS02065 f2ed1d53738e0ab2707a3316bbb56b45 206 Gene3D G3DSA:3.30.70.20 92 154 2.4E-11 T 29-03-2018 MC49_RS02065 f2ed1d53738e0ab2707a3316bbb56b45 206 Pfam PF12798 4Fe-4S binding domain 147 167 0.007 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MC49_RS02065 f2ed1d53738e0ab2707a3316bbb56b45 206 Gene3D G3DSA:3.30.70.20 64 91 3.3E-14 T 29-03-2018 MC49_RS02065 f2ed1d53738e0ab2707a3316bbb56b45 206 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 82 93 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MC49_RS11915 b2655b62ca9f04405c7efcf3cbfda96f 906 Gene3D G3DSA:1.10.8.60 810 905 2.5E-12 T 29-03-2018 MC49_RS11915 b2655b62ca9f04405c7efcf3cbfda96f 906 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 223 335 5.1E-10 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MC49_RS11915 b2655b62ca9f04405c7efcf3cbfda96f 906 SMART SM00382 643 802 1.7E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS11915 b2655b62ca9f04405c7efcf3cbfda96f 906 SMART SM00382 217 361 4.9E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS11915 b2655b62ca9f04405c7efcf3cbfda96f 906 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 809 887 6.8E-12 T 29-03-2018 IPR019489 Clp ATPase, C-terminal MC49_RS11915 b2655b62ca9f04405c7efcf3cbfda96f 906 Pfam PF07724 AAA domain (Cdc48 subfamily) 642 803 2.0E-36 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MC49_RS11915 b2655b62ca9f04405c7efcf3cbfda96f 906 SMART SM01086 809 901 3.0E-10 T 29-03-2018 IPR019489 Clp ATPase, C-terminal MC49_RS11915 b2655b62ca9f04405c7efcf3cbfda96f 906 SUPERFAMILY SSF52540 180 504 3.49E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS11915 b2655b62ca9f04405c7efcf3cbfda96f 906 SUPERFAMILY SSF81923 13 125 2.35E-7 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 MC49_RS11915 b2655b62ca9f04405c7efcf3cbfda96f 906 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 692 710 6.9E-29 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 MC49_RS11915 b2655b62ca9f04405c7efcf3cbfda96f 906 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 647 665 6.9E-29 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 MC49_RS11915 b2655b62ca9f04405c7efcf3cbfda96f 906 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 721 739 6.9E-29 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 MC49_RS11915 b2655b62ca9f04405c7efcf3cbfda96f 906 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 754 768 6.9E-29 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 MC49_RS11915 b2655b62ca9f04405c7efcf3cbfda96f 906 Gene3D G3DSA:3.40.50.300 609 809 1.2E-28 T 29-03-2018 MC49_RS11915 b2655b62ca9f04405c7efcf3cbfda96f 906 SUPERFAMILY SSF52540 592 876 3.09E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS11915 b2655b62ca9f04405c7efcf3cbfda96f 906 Gene3D G3DSA:3.40.50.300 176 361 1.8E-21 T 29-03-2018 MC49_RS11915 b2655b62ca9f04405c7efcf3cbfda96f 906 Gene3D G3DSA:1.10.1780.10 5 160 5.8E-18 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 MC49_RS11915 b2655b62ca9f04405c7efcf3cbfda96f 906 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 677 695 - T 29-03-2018 IPR028299 ClpA/B, conserved site 2 MC49_RS11915 b2655b62ca9f04405c7efcf3cbfda96f 906 TIGRFAM TIGR03345 VI_ClpV1: type VI secretion ATPase, ClpV1 family 13 893 0.0 T 29-03-2018 IPR017729 Type VI secretion system, ATPase ClpV1 MC49_RS11915 b2655b62ca9f04405c7efcf3cbfda96f 906 Gene3D G3DSA:1.10.8.60 362 593 7.6E-36 T 29-03-2018 MC49_RS04315 430174768c8a00ee16d97d1c6a53a962 230 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 21 142 4.2E-41 T 29-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 MC49_RS04315 430174768c8a00ee16d97d1c6a53a962 230 ProSitePatterns PS00635 Gram-negative pili assembly chaperone signature. 97 114 - T 29-03-2018 IPR018046 Pili assembly chaperone, conserved site MC49_RS04315 430174768c8a00ee16d97d1c6a53a962 230 Gene3D G3DSA:2.60.40.10 144 230 4.5E-20 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS04315 430174768c8a00ee16d97d1c6a53a962 230 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 164 222 3.7E-15 T 29-03-2018 IPR016148 Pili assembly chaperone, C-terminal MC49_RS04315 430174768c8a00ee16d97d1c6a53a962 230 SUPERFAMILY SSF49584 136 224 1.44E-18 T 29-03-2018 IPR016148 Pili assembly chaperone, C-terminal MC49_RS04315 430174768c8a00ee16d97d1c6a53a962 230 Gene3D G3DSA:2.60.40.10 20 143 1.6E-33 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS04315 430174768c8a00ee16d97d1c6a53a962 230 PRINTS PR00969 Pili chaperone signature 70 91 5.1E-30 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS04315 430174768c8a00ee16d97d1c6a53a962 230 PRINTS PR00969 Pili chaperone signature 98 115 5.1E-30 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS04315 430174768c8a00ee16d97d1c6a53a962 230 PRINTS PR00969 Pili chaperone signature 124 139 5.1E-30 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS04315 430174768c8a00ee16d97d1c6a53a962 230 PRINTS PR00969 Pili chaperone signature 159 174 5.1E-30 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS04315 430174768c8a00ee16d97d1c6a53a962 230 PRINTS PR00969 Pili chaperone signature 21 30 5.1E-30 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS04315 430174768c8a00ee16d97d1c6a53a962 230 SUPERFAMILY SSF49354 16 142 8.9E-39 T 29-03-2018 IPR008962 PapD-like MC49_RS11115 19aa25af35c7719710312494e9b5913a 361 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 188 207 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site MC49_RS11115 19aa25af35c7719710312494e9b5913a 361 Pfam PF00266 Aminotransferase class-V 4 349 1.5E-61 T 29-03-2018 IPR000192 Aminotransferase class V domain MC49_RS11115 19aa25af35c7719710312494e9b5913a 361 Gene3D G3DSA:3.90.1150.10 259 359 1.1E-33 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS11115 19aa25af35c7719710312494e9b5913a 361 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 2 360 50.56 T 29-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 MC49_RS11115 19aa25af35c7719710312494e9b5913a 361 SUPERFAMILY SSF53383 1 359 2.99E-113 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS11115 19aa25af35c7719710312494e9b5913a 361 PIRSF PIRSF000525 1 361 1.2E-147 T 29-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 MC49_RS11115 19aa25af35c7719710312494e9b5913a 361 Gene3D G3DSA:3.40.640.10 16 258 2.2E-24 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS11115 19aa25af35c7719710312494e9b5913a 361 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 4 360 1.7E-153 T 29-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 MC49_RS10320 4d3252fef7dadb08e34c350104c1387b 546 Gene3D G3DSA:3.40.120.10 215 332 4.7E-21 T 29-03-2018 MC49_RS10320 4d3252fef7dadb08e34c350104c1387b 546 TIGRFAM TIGR01132 pgm: phosphoglucomutase, alpha-D-glucose phosphate-specific 4 544 2.5E-298 T 29-03-2018 IPR005852 Phosphoglucomutase, alpha-D-glucose specific GO:0004614|GO:0005975 KEGG: 00010+5.4.2.2|KEGG: 00030+5.4.2.2|KEGG: 00052+5.4.2.2|KEGG: 00230+5.4.2.2|KEGG: 00500+5.4.2.2|KEGG: 00520+5.4.2.2|KEGG: 00521+5.4.2.2|MetaCyc: PWY-2723|MetaCyc: PWY-3801|MetaCyc: PWY-5384|MetaCyc: PWY-5661|MetaCyc: PWY-5940|MetaCyc: PWY-5941|MetaCyc: PWY-622|MetaCyc: PWY-6317|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|MetaCyc: PWY-7343 MC49_RS10320 4d3252fef7dadb08e34c350104c1387b 546 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 141 150 - T 29-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MC49_RS10320 4d3252fef7dadb08e34c350104c1387b 546 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 211 318 6.0E-17 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MC49_RS10320 4d3252fef7dadb08e34c350104c1387b 546 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 482 539 5.5E-7 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MC49_RS10320 4d3252fef7dadb08e34c350104c1387b 546 SUPERFAMILY SSF53738 27 236 9.65E-52 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MC49_RS10320 4d3252fef7dadb08e34c350104c1387b 546 Gene3D G3DSA:3.30.310.50 444 546 1.2E-19 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MC49_RS10320 4d3252fef7dadb08e34c350104c1387b 546 SUPERFAMILY SSF55957 433 544 2.88E-18 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MC49_RS10320 4d3252fef7dadb08e34c350104c1387b 546 Gene3D G3DSA:3.40.120.10 13 214 4.0E-48 T 29-03-2018 MC49_RS10320 4d3252fef7dadb08e34c350104c1387b 546 SUPERFAMILY SSF53738 306 448 2.32E-31 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MC49_RS10320 4d3252fef7dadb08e34c350104c1387b 546 SUPERFAMILY SSF53738 210 318 8.12E-8 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MC49_RS10320 4d3252fef7dadb08e34c350104c1387b 546 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 41 179 4.6E-38 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MC49_RS10320 4d3252fef7dadb08e34c350104c1387b 546 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 321 441 5.4E-28 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MC49_RS10320 4d3252fef7dadb08e34c350104c1387b 546 Gene3D G3DSA:3.40.120.10 333 442 2.5E-25 T 29-03-2018 MC49_RS17880 5d4d3ce588fef6accfcdb55f99e7e9d6 328 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 48 61 - T 29-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 MC49_RS17880 5d4d3ce588fef6accfcdb55f99e7e9d6 328 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 22 311 4.1E-77 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MC49_RS17880 5d4d3ce588fef6accfcdb55f99e7e9d6 328 Gene3D G3DSA:3.40.50.1100 111 328 3.6E-51 T 29-03-2018 MC49_RS17880 5d4d3ce588fef6accfcdb55f99e7e9d6 328 Gene3D G3DSA:3.40.50.1100 56 110 1.3E-20 T 29-03-2018 MC49_RS17880 5d4d3ce588fef6accfcdb55f99e7e9d6 328 SUPERFAMILY SSF53686 9 320 1.96E-91 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MC49_RS15875 9d7144120b86307568f73aeb7c88b111 266 Gene3D G3DSA:3.40.50.300 9 249 1.1E-54 T 29-03-2018 MC49_RS15875 9d7144120b86307568f73aeb7c88b111 266 SUPERFAMILY SSF52540 6 239 1.46E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS15875 9d7144120b86307568f73aeb7c88b111 266 Pfam PF00005 ABC transporter 29 176 1.4E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS15875 9d7144120b86307568f73aeb7c88b111 266 SMART SM00382 37 225 3.7E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS07150 85628f017fec7b54f05168ea26b68cc9 388 ProSitePatterns PS00737 Thiolases signature 2. 332 348 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 MC49_RS07150 85628f017fec7b54f05168ea26b68cc9 388 Pfam PF02803 Thiolase, C-terminal domain 261 385 8.0E-48 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 MC49_RS07150 85628f017fec7b54f05168ea26b68cc9 388 SUPERFAMILY SSF53901 1 258 3.8E-74 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MC49_RS07150 85628f017fec7b54f05168ea26b68cc9 388 ProSitePatterns PS00099 Thiolases active site. 367 380 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 MC49_RS07150 85628f017fec7b54f05168ea26b68cc9 388 PIRSF PIRSF000429 1 387 5.8E-129 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MC49_RS07150 85628f017fec7b54f05168ea26b68cc9 388 Pfam PF00108 Thiolase, N-terminal domain 4 252 5.9E-75 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 MC49_RS07150 85628f017fec7b54f05168ea26b68cc9 388 Gene3D G3DSA:3.40.47.10 1 258 2.7E-50 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MC49_RS07150 85628f017fec7b54f05168ea26b68cc9 388 SUPERFAMILY SSF53901 262 385 3.67E-42 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MC49_RS07150 85628f017fec7b54f05168ea26b68cc9 388 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 384 7.3E-137 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 MC49_RS07150 85628f017fec7b54f05168ea26b68cc9 388 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 MC49_RS07150 85628f017fec7b54f05168ea26b68cc9 388 Gene3D G3DSA:3.40.47.10 259 383 1.9E-32 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MC49_RS11415 9158b9225cd8c72dbe3ef854791ed354 110 PIRSF PIRSF020632 3 110 1.8E-41 T 29-03-2018 IPR014510 Tellurite resistance predicted, YeaR MC49_RS11415 9158b9225cd8c72dbe3ef854791ed354 110 Gene3D G3DSA:2.60.120.10 7 110 4.8E-34 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MC49_RS11415 9158b9225cd8c72dbe3ef854791ed354 110 Pfam PF09313 Domain of unknown function (DUF1971) 14 98 3.1E-25 T 29-03-2018 IPR015392 Domain of unknown function DUF1971 MC49_RS11415 9158b9225cd8c72dbe3ef854791ed354 110 SUPERFAMILY SSF51197 4 107 1.25E-34 T 29-03-2018 MC49_RS04165 45d53e98b9ae88d2567b52bea3a6f87c 103 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 29-03-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04165 45d53e98b9ae88d2567b52bea3a6f87c 103 SUPERFAMILY SSF54999 5 101 1.26E-36 T 29-03-2018 IPR027486 Ribosomal protein S10 domain MC49_RS04165 45d53e98b9ae88d2567b52bea3a6f87c 103 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 27.353 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04165 45d53e98b9ae88d2567b52bea3a6f87c 103 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 1.0E-46 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04165 45d53e98b9ae88d2567b52bea3a6f87c 103 SMART SM01403 7 101 1.0E-56 T 29-03-2018 IPR027486 Ribosomal protein S10 domain MC49_RS04165 45d53e98b9ae88d2567b52bea3a6f87c 103 Pfam PF00338 Ribosomal protein S10p/S20e 7 100 2.1E-35 T 29-03-2018 IPR027486 Ribosomal protein S10 domain MC49_RS04165 45d53e98b9ae88d2567b52bea3a6f87c 103 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 1.2E-18 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04165 45d53e98b9ae88d2567b52bea3a6f87c 103 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 1.2E-18 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04165 45d53e98b9ae88d2567b52bea3a6f87c 103 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 1.2E-18 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04165 45d53e98b9ae88d2567b52bea3a6f87c 103 Gene3D G3DSA:3.30.70.600 3 102 1.4E-35 T 29-03-2018 IPR027486 Ribosomal protein S10 domain MC49_RS16295 73253fe3057d216e991e4c52a2279ce0 405 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 64 392 8.9E-81 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MC49_RS16295 73253fe3057d216e991e4c52a2279ce0 405 SUPERFAMILY SSF111369 78 318 5.89E-58 T 29-03-2018 MC49_RS16295 73253fe3057d216e991e4c52a2279ce0 405 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 75 311 1.6E-16 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MC49_RS16295 73253fe3057d216e991e4c52a2279ce0 405 Gene3D G3DSA:2.40.50.100 194 394 3.9E-5 T 29-03-2018 MC49_RS16295 73253fe3057d216e991e4c52a2279ce0 405 Gene3D G3DSA:2.40.50.100 60 121 2.2E-7 T 29-03-2018 MC49_RS16295 73253fe3057d216e991e4c52a2279ce0 405 Gene3D G3DSA:1.10.287.470 130 193 1.9E-15 T 29-03-2018 MC49_RS12130 ded56b76d33bb867e98e663f7800c280 615 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 331 345 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MC49_RS12130 ded56b76d33bb867e98e663f7800c280 615 SUPERFAMILY SSF53067 20 196 1.75E-50 T 29-03-2018 MC49_RS12130 ded56b76d33bb867e98e663f7800c280 615 Pfam PF00012 Hsp70 protein 22 598 1.4E-194 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MC49_RS12130 ded56b76d33bb867e98e663f7800c280 615 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 24 31 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MC49_RS12130 ded56b76d33bb867e98e663f7800c280 615 PRINTS PR00301 70kDa heat shock protein signature 211 221 6.6E-56 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MC49_RS12130 ded56b76d33bb867e98e663f7800c280 615 PRINTS PR00301 70kDa heat shock protein signature 465 481 6.6E-56 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MC49_RS12130 ded56b76d33bb867e98e663f7800c280 615 PRINTS PR00301 70kDa heat shock protein signature 384 403 6.6E-56 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MC49_RS12130 ded56b76d33bb867e98e663f7800c280 615 PRINTS PR00301 70kDa heat shock protein signature 359 379 6.6E-56 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MC49_RS12130 ded56b76d33bb867e98e663f7800c280 615 PRINTS PR00301 70kDa heat shock protein signature 20 33 6.6E-56 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MC49_RS12130 ded56b76d33bb867e98e663f7800c280 615 PRINTS PR00301 70kDa heat shock protein signature 152 172 6.6E-56 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MC49_RS12130 ded56b76d33bb867e98e663f7800c280 615 PRINTS PR00301 70kDa heat shock protein signature 328 344 6.6E-56 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MC49_RS12130 ded56b76d33bb867e98e663f7800c280 615 PRINTS PR00301 70kDa heat shock protein signature 48 60 6.6E-56 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MC49_RS12130 ded56b76d33bb867e98e663f7800c280 615 Gene3D G3DSA:1.20.1270.10 528 614 5.2E-14 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain MC49_RS12130 ded56b76d33bb867e98e663f7800c280 615 SUPERFAMILY SSF100920 383 534 1.01E-50 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 MC49_RS12130 ded56b76d33bb867e98e663f7800c280 615 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 205 218 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MC49_RS12130 ded56b76d33bb867e98e663f7800c280 615 TIGRFAM TIGR01991 HscA: Fe-S protein assembly chaperone HscA 21 614 2.7E-271 T 29-03-2018 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 MC49_RS12130 ded56b76d33bb867e98e663f7800c280 615 Hamap MF_00679 Chaperone protein HscA [hscA]. 1 615 45.408 T 29-03-2018 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 MC49_RS12130 ded56b76d33bb867e98e663f7800c280 615 SUPERFAMILY SSF53067 200 376 2.11E-52 T 29-03-2018 MC49_RS12130 ded56b76d33bb867e98e663f7800c280 615 SUPERFAMILY SSF100934 503 614 1.92E-35 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain MC49_RS12130 ded56b76d33bb867e98e663f7800c280 615 Gene3D G3DSA:3.30.420.40 20 208 1.4E-55 T 29-03-2018 MC49_RS12130 ded56b76d33bb867e98e663f7800c280 615 Gene3D G3DSA:3.30.420.40 209 357 1.4E-40 T 29-03-2018 MC49_RS12130 ded56b76d33bb867e98e663f7800c280 615 Gene3D G3DSA:2.60.34.10 386 527 2.6E-48 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 MC49_RS02120 294fcb22fe1d264de068281e245c8443 548 PRINTS PR00298 60kDa chaperonin signature 27 53 3.3E-74 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MC49_RS02120 294fcb22fe1d264de068281e245c8443 548 PRINTS PR00298 60kDa chaperonin signature 83 110 3.3E-74 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MC49_RS02120 294fcb22fe1d264de068281e245c8443 548 PRINTS PR00298 60kDa chaperonin signature 398 419 3.3E-74 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MC49_RS02120 294fcb22fe1d264de068281e245c8443 548 PRINTS PR00298 60kDa chaperonin signature 350 375 3.3E-74 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MC49_RS02120 294fcb22fe1d264de068281e245c8443 548 PRINTS PR00298 60kDa chaperonin signature 268 291 3.3E-74 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MC49_RS02120 294fcb22fe1d264de068281e245c8443 548 Hamap MF_00600 60 kDa chaperonin [groL]. 2 547 41.523 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MC49_RS02120 294fcb22fe1d264de068281e245c8443 548 SUPERFAMILY SSF54849 137 203 2.15E-24 T 29-03-2018 MC49_RS02120 294fcb22fe1d264de068281e245c8443 548 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 29-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MC49_RS02120 294fcb22fe1d264de068281e245c8443 548 Gene3D G3DSA:3.50.7.10 185 373 1.8E-97 T 29-03-2018 IPR027409 GroEL-like apical domain MC49_RS02120 294fcb22fe1d264de068281e245c8443 548 SUPERFAMILY SSF48592 406 521 1.83E-77 T 29-03-2018 MC49_RS02120 294fcb22fe1d264de068281e245c8443 548 SUPERFAMILY SSF48592 7 134 1.83E-77 T 29-03-2018 MC49_RS02120 294fcb22fe1d264de068281e245c8443 548 Gene3D G3DSA:1.10.560.10 374 516 5.2E-26 T 29-03-2018 IPR027413 GroEL-like equatorial domain MC49_RS02120 294fcb22fe1d264de068281e245c8443 548 Gene3D G3DSA:1.10.560.10 1 184 1.7E-43 T 29-03-2018 IPR027413 GroEL-like equatorial domain MC49_RS02120 294fcb22fe1d264de068281e245c8443 548 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 526 4.0E-253 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MC49_RS02120 294fcb22fe1d264de068281e245c8443 548 SUPERFAMILY SSF52029 184 376 5.93E-83 T 29-03-2018 IPR027409 GroEL-like apical domain MC49_RS02120 294fcb22fe1d264de068281e245c8443 548 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 522 1.2E-93 T 29-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 MC49_RS16245 61e3c71079779aaf4bf9214ed9f2943d 100 Pfam PF11731 Pathogenicity locus 8 91 3.3E-33 T 29-03-2018 IPR021725 Pathogenicity locus MC49_RS16245 61e3c71079779aaf4bf9214ed9f2943d 100 Gene3D G3DSA:1.10.150.20 5 97 8.4E-21 T 29-03-2018 MC49_RS14000 efd9423a7198cc620cc51bb1291f2ece 291 Gene3D G3DSA:3.80.10.10 153 288 3.0E-33 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like MC49_RS14000 efd9423a7198cc620cc51bb1291f2ece 291 Gene3D G3DSA:3.80.10.10 100 152 6.6E-15 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like MC49_RS14000 efd9423a7198cc620cc51bb1291f2ece 291 SMART SM00364 98 117 180.0 T 29-03-2018 MC49_RS14000 efd9423a7198cc620cc51bb1291f2ece 291 SMART SM00364 121 140 100.0 T 29-03-2018 MC49_RS14000 efd9423a7198cc620cc51bb1291f2ece 291 SMART SM00364 236 255 9.0 T 29-03-2018 MC49_RS14000 efd9423a7198cc620cc51bb1291f2ece 291 SMART SM00364 213 232 18.0 T 29-03-2018 MC49_RS14000 efd9423a7198cc620cc51bb1291f2ece 291 Gene3D G3DSA:3.80.10.10 1 99 1.8E-20 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like MC49_RS14000 efd9423a7198cc620cc51bb1291f2ece 291 SMART SM00369 144 167 15.0 T 29-03-2018 IPR003591 Leucine-rich repeat, typical subtype MC49_RS14000 efd9423a7198cc620cc51bb1291f2ece 291 SMART SM00369 236 258 3.8 T 29-03-2018 IPR003591 Leucine-rich repeat, typical subtype MC49_RS14000 efd9423a7198cc620cc51bb1291f2ece 291 SMART SM00369 213 234 9.6 T 29-03-2018 IPR003591 Leucine-rich repeat, typical subtype MC49_RS14000 efd9423a7198cc620cc51bb1291f2ece 291 SMART SM00369 98 120 12.0 T 29-03-2018 IPR003591 Leucine-rich repeat, typical subtype MC49_RS14000 efd9423a7198cc620cc51bb1291f2ece 291 SMART SM00369 52 75 5.0 T 29-03-2018 IPR003591 Leucine-rich repeat, typical subtype MC49_RS14000 efd9423a7198cc620cc51bb1291f2ece 291 SMART SM00369 121 143 53.0 T 29-03-2018 IPR003591 Leucine-rich repeat, typical subtype MC49_RS14000 efd9423a7198cc620cc51bb1291f2ece 291 SMART SM00369 190 212 37.0 T 29-03-2018 IPR003591 Leucine-rich repeat, typical subtype MC49_RS14000 efd9423a7198cc620cc51bb1291f2ece 291 SMART SM00369 259 282 0.091 T 29-03-2018 IPR003591 Leucine-rich repeat, typical subtype MC49_RS14000 efd9423a7198cc620cc51bb1291f2ece 291 SUPERFAMILY SSF52058 11 281 4.08E-60 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like MC49_RS14000 efd9423a7198cc620cc51bb1291f2ece 291 Pfam PF13855 Leucine rich repeat 215 272 1.9E-10 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 MC49_RS14000 efd9423a7198cc620cc51bb1291f2ece 291 Pfam PF13855 Leucine rich repeat 54 109 3.7E-9 T 29-03-2018 IPR001611 Leucine-rich repeat GO:0005515 MC49_RS12045 557df41308b1e9bbabdcf47fff32604f 237 Gene3D G3DSA:3.30.1150.10 74 236 7.7E-16 T 29-03-2018 MC49_RS12045 557df41308b1e9bbabdcf47fff32604f 237 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 167 228 4.3E-7 T 29-03-2018 IPR006260 TonB, C-terminal GO:0006810 MC49_RS12045 557df41308b1e9bbabdcf47fff32604f 237 SUPERFAMILY SSF74653 140 235 7.06E-15 T 29-03-2018 MC49_RS12045 557df41308b1e9bbabdcf47fff32604f 237 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 167 235 2.8E-11 T 29-03-2018 IPR006260 TonB, C-terminal GO:0006810 MC49_RS03160 faa7e1c55ba61f9e6e2c0bdfc9c2288d 253 SUPERFAMILY SSF51556 11 252 2.34E-50 T 29-03-2018 IPR032466 Metal-dependent hydrolase MC49_RS03160 faa7e1c55ba61f9e6e2c0bdfc9c2288d 253 Gene3D G3DSA:3.20.20.140 10 253 2.0E-52 T 29-03-2018 MC49_RS03160 faa7e1c55ba61f9e6e2c0bdfc9c2288d 253 Pfam PF01026 TatD related DNase 12 252 2.2E-46 T 29-03-2018 IPR001130 TatD family GO:0016788 MC49_RS03160 faa7e1c55ba61f9e6e2c0bdfc9c2288d 253 PIRSF PIRSF005902 1 253 2.4E-45 T 29-03-2018 IPR001130 TatD family GO:0016788 MC49_RS01445 cf5a5e38260f0d9a5ea2dca1d3d7a5f6 162 Pfam PF04386 Stringent starvation protein B 9 162 1.4E-43 T 29-03-2018 IPR007481 Stringent starvation protein B MC49_RS01445 cf5a5e38260f0d9a5ea2dca1d3d7a5f6 162 Gene3D G3DSA:2.30.30.220 10 107 1.4E-42 T 29-03-2018 IPR007481 Stringent starvation protein B MC49_RS01445 cf5a5e38260f0d9a5ea2dca1d3d7a5f6 162 PIRSF PIRSF005276 3 162 4.5E-59 T 29-03-2018 IPR007481 Stringent starvation protein B MC49_RS01445 cf5a5e38260f0d9a5ea2dca1d3d7a5f6 162 SUPERFAMILY SSF101738 5 117 3.66E-49 T 29-03-2018 IPR007481 Stringent starvation protein B MC49_RS01730 64cbe6a27cd42209429dab08875e0366 724 Gene3D G3DSA:2.40.170.20 179 724 1.3E-75 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MC49_RS01730 64cbe6a27cd42209429dab08875e0366 724 Gene3D G3DSA:2.170.130.10 24 178 1.1E-28 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MC49_RS01730 64cbe6a27cd42209429dab08875e0366 724 Pfam PF00593 TonB dependent receptor 249 722 7.4E-61 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MC49_RS01730 64cbe6a27cd42209429dab08875e0366 724 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 65 723 6.2E-133 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 MC49_RS01730 64cbe6a27cd42209429dab08875e0366 724 Pfam PF07715 TonB-dependent Receptor Plug Domain 64 166 5.2E-21 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MC49_RS01730 64cbe6a27cd42209429dab08875e0366 724 SUPERFAMILY SSF56935 27 724 3.66E-130 T 29-03-2018 MC49_RS16755 e1b1158d244fa038ba4708a3778fb8e3 269 SUPERFAMILY SSF51735 3 159 9.28E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS16755 e1b1158d244fa038ba4708a3778fb8e3 269 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 162 266 4.0E-39 T 29-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MC49_RS16755 e1b1158d244fa038ba4708a3778fb8e3 269 SUPERFAMILY SSF48179 161 268 2.04E-38 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MC49_RS16755 e1b1158d244fa038ba4708a3778fb8e3 269 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 5 266 7.8E-89 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 MC49_RS16755 e1b1158d244fa038ba4708a3778fb8e3 269 Gene3D G3DSA:1.10.3730.10 160 269 4.4E-45 T 29-03-2018 MC49_RS16755 e1b1158d244fa038ba4708a3778fb8e3 269 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 99 1.3E-18 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal MC49_RS16755 e1b1158d244fa038ba4708a3778fb8e3 269 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 3 266 27.747 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 MC49_RS16755 e1b1158d244fa038ba4708a3778fb8e3 269 Gene3D G3DSA:3.40.50.720 1 159 1.2E-34 T 29-03-2018 MC49_RS16755 e1b1158d244fa038ba4708a3778fb8e3 269 PIRSF PIRSF000193 2 269 1.1E-89 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 MC49_RS16755 e1b1158d244fa038ba4708a3778fb8e3 269 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 222 244 - T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 MC49_RS06630 a0674d2546a79a1cc2523b99e5697c18 166 Pfam PF04345 Chorismate lyase 14 162 5.6E-31 T 29-03-2018 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148|MetaCyc: PWY-7742|MetaCyc: PWY-7745 MC49_RS06630 a0674d2546a79a1cc2523b99e5697c18 166 Hamap MF_01632 Chorismate pyruvate-lyase [ubiC]. 10 164 24.68 T 29-03-2018 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148|MetaCyc: PWY-7742|MetaCyc: PWY-7745 MC49_RS06630 a0674d2546a79a1cc2523b99e5697c18 166 Gene3D G3DSA:3.40.1410.10 2 164 1.0E-41 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain MC49_RS06630 a0674d2546a79a1cc2523b99e5697c18 166 SUPERFAMILY SSF64288 16 164 1.03E-42 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain MC49_RS09520 5ade23a52a9d1b8ab2699593cb83cdcd 157 SUPERFAMILY SSF51197 1 153 7.69E-42 T 29-03-2018 MC49_RS09520 5ade23a52a9d1b8ab2699593cb83cdcd 157 Pfam PF04074 Domain of unknown function (DUF386) 1 151 5.8E-39 T 29-03-2018 IPR004375 YhcH/YjgK/YiaL family MC49_RS09520 5ade23a52a9d1b8ab2699593cb83cdcd 157 Gene3D G3DSA:2.60.120.370 1 155 5.2E-41 T 29-03-2018 IPR004375 YhcH/YjgK/YiaL family MC49_RS09520 5ade23a52a9d1b8ab2699593cb83cdcd 157 TIGRFAM TIGR00022 TIGR00022: YhcH/YjgK/YiaL family protein 1 153 1.5E-41 T 29-03-2018 IPR004375 YhcH/YjgK/YiaL family MC49_RS00815 c699ee047af22e6ee6e25a36297b74c4 300 Gene3D G3DSA:1.10.1040.10 167 293 2.1E-32 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MC49_RS00815 c699ee047af22e6ee6e25a36297b74c4 300 SUPERFAMILY SSF48179 168 288 7.48E-32 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MC49_RS00815 c699ee047af22e6ee6e25a36297b74c4 300 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 290 1.7E-67 T 29-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 MC49_RS00815 c699ee047af22e6ee6e25a36297b74c4 300 SUPERFAMILY SSF51735 1 166 1.6E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS00815 c699ee047af22e6ee6e25a36297b74c4 300 Gene3D G3DSA:3.40.50.720 1 166 5.8E-20 T 29-03-2018 MC49_RS00815 c699ee047af22e6ee6e25a36297b74c4 300 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 142 4.6E-23 T 29-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 MC49_RS00815 c699ee047af22e6ee6e25a36297b74c4 300 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 168 288 1.2E-33 T 29-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 MC49_RS15205 a93ac8eb682c3141702d08635e27b725 223 SUPERFAMILY SSF52172 1 175 2.05E-37 T 29-03-2018 IPR011006 CheY-like superfamily MC49_RS15205 a93ac8eb682c3141702d08635e27b725 223 SMART SM00862 145 216 1.3E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MC49_RS15205 a93ac8eb682c3141702d08635e27b725 223 Gene3D G3DSA:3.40.50.2300 1 119 2.4E-32 T 29-03-2018 MC49_RS15205 a93ac8eb682c3141702d08635e27b725 223 Gene3D G3DSA:1.10.10.10 120 223 8.1E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS15205 a93ac8eb682c3141702d08635e27b725 223 Pfam PF00072 Response regulator receiver domain 3 112 2.0E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS15205 a93ac8eb682c3141702d08635e27b725 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 215 8.0E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MC49_RS15205 a93ac8eb682c3141702d08635e27b725 223 SMART SM00448 1 112 9.0E-38 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS00930 d09f664f734eb879bf6343ccf21d03e3 1228 Gene3D G3DSA:1.10.287.620 506 690 1.7E-5 T 29-03-2018 MC49_RS00930 d09f664f734eb879bf6343ccf21d03e3 1228 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1107 1180 4.6E-16 T 29-03-2018 MC49_RS00930 d09f664f734eb879bf6343ccf21d03e3 1228 Gene3D G3DSA:3.40.50.300 1 234 4.9E-29 T 29-03-2018 MC49_RS00930 d09f664f734eb879bf6343ccf21d03e3 1228 Gene3D G3DSA:1.10.287.510 813 930 4.9E-5 T 29-03-2018 MC49_RS00930 d09f664f734eb879bf6343ccf21d03e3 1228 Gene3D G3DSA:3.40.50.300 978 1211 4.1E-10 T 29-03-2018 MC49_RS00930 d09f664f734eb879bf6343ccf21d03e3 1228 Gene3D G3DSA:1.20.5.50 284 421 0.036 T 29-03-2018 MC49_RS00930 d09f664f734eb879bf6343ccf21d03e3 1228 Pfam PF13476 AAA domain 6 380 2.4E-20 T 29-03-2018 MC49_RS00930 d09f664f734eb879bf6343ccf21d03e3 1228 SUPERFAMILY SSF52540 26 225 8.08E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS00930 d09f664f734eb879bf6343ccf21d03e3 1228 SUPERFAMILY SSF52540 1116 1202 8.08E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS17010 1b17f96274d6ad2682cdab50c5d29ac8 400 Pfam PF12704 MacB-like periplasmic core domain 27 209 3.5E-16 T 29-03-2018 IPR025857 MacB-like periplasmic core domain MC49_RS17010 1b17f96274d6ad2682cdab50c5d29ac8 400 Pfam PF02687 FtsX-like permease family 296 393 4.3E-11 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MC49_RS17010 1b17f96274d6ad2682cdab50c5d29ac8 400 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 5 400 6.0E-129 T 29-03-2018 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 MC49_RS11820 c7d5c61b5bcdf9d247a69a7b59f9191a 2477 Gene3D G3DSA:1.10.287.510 2029 2217 7.3E-4 T 29-03-2018 MC49_RS11820 c7d5c61b5bcdf9d247a69a7b59f9191a 2477 Pfam PF03538 Salmonella virulence plasmid 28.1kDa A protein 84 231 2.0E-18 T 29-03-2018 IPR018003 Insecticidal toxin complex/plasmid virulence protein MC49_RS07550 7b93311fe6aef30a199a6cd2802d03b6 317 ProSitePatterns PS00958 Transaldolase active site. 129 146 - T 29-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 MC49_RS07550 7b93311fe6aef30a199a6cd2802d03b6 317 Gene3D G3DSA:3.20.20.70 2 316 3.2E-122 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS07550 7b93311fe6aef30a199a6cd2802d03b6 317 TIGRFAM TIGR00874 talAB: transaldolase 4 316 6.4E-162 T 29-03-2018 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 MC49_RS07550 7b93311fe6aef30a199a6cd2802d03b6 317 ProSitePatterns PS01054 Transaldolase signature 1. 31 39 - T 29-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 MC49_RS07550 7b93311fe6aef30a199a6cd2802d03b6 317 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 14 313 5.1E-101 T 29-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 MC49_RS07550 7b93311fe6aef30a199a6cd2802d03b6 317 SUPERFAMILY SSF51569 1 316 9.32E-116 T 29-03-2018 MC49_RS07550 7b93311fe6aef30a199a6cd2802d03b6 317 Hamap MF_00492 Transaldolase [tal]. 2 317 51.601 T 29-03-2018 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 MC49_RS18905 6a343af81cb31e62587594085e09774b 385 Gene3D G3DSA:3.40.50.1980 175 362 1.4E-41 T 29-03-2018 MC49_RS18905 6a343af81cb31e62587594085e09774b 385 SUPERFAMILY SSF53807 35 356 1.1E-47 T 29-03-2018 MC49_RS18905 6a343af81cb31e62587594085e09774b 385 Pfam PF01497 Periplasmic binding protein 74 333 3.6E-22 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 MC49_RS18905 6a343af81cb31e62587594085e09774b 385 Gene3D G3DSA:3.40.50.1980 33 174 7.1E-21 T 29-03-2018 MC49_RS03975 039ee6fff386a2c89577414c4f465fa1 272 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 3 270 6.3E-92 T 29-03-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 MC49_RS03975 039ee6fff386a2c89577414c4f465fa1 272 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 6 88 1.1E-24 T 29-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 MC49_RS03975 039ee6fff386a2c89577414c4f465fa1 272 SUPERFAMILY SSF53223 1 101 1.44E-30 T 29-03-2018 MC49_RS03975 039ee6fff386a2c89577414c4f465fa1 272 SUPERFAMILY SSF51735 102 262 1.9E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS03975 039ee6fff386a2c89577414c4f465fa1 272 Gene3D G3DSA:3.40.50.10860 1 110 9.6E-36 T 29-03-2018 MC49_RS03975 039ee6fff386a2c89577414c4f465fa1 272 Gene3D G3DSA:3.40.50.720 111 272 3.8E-29 T 29-03-2018 MC49_RS03975 039ee6fff386a2c89577414c4f465fa1 272 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 1 269 31.196 T 29-03-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 MC49_RS03975 039ee6fff386a2c89577414c4f465fa1 272 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 121 190 4.2E-9 T 29-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase MC49_RS08255 5bb7031027e42e4211743f08f572202b 373 Pfam PF01551 Peptidase family M23 273 366 2.0E-29 T 29-03-2018 IPR016047 Peptidase M23 MC49_RS08255 5bb7031027e42e4211743f08f572202b 373 SUPERFAMILY SSF51261 115 370 2.14E-52 T 29-03-2018 IPR011055 Duplicated hybrid motif MC49_RS08255 5bb7031027e42e4211743f08f572202b 373 Gene3D G3DSA:3.10.350.10 109 184 2.0E-10 T 29-03-2018 MC49_RS08255 5bb7031027e42e4211743f08f572202b 373 Pfam PF01476 LysM domain 116 158 1.4E-8 T 29-03-2018 IPR018392 LysM domain MC49_RS08255 5bb7031027e42e4211743f08f572202b 373 SMART SM00257 115 159 9.7E-9 T 29-03-2018 IPR018392 LysM domain MC49_RS08255 5bb7031027e42e4211743f08f572202b 373 Gene3D G3DSA:2.70.70.10 192 373 1.2E-38 T 29-03-2018 MC49_RS02650 e078191e2e506e83738203550b636241 423 Gene3D G3DSA:1.20.1250.20 209 409 7.2E-15 T 29-03-2018 MC49_RS02650 e078191e2e506e83738203550b636241 423 Pfam PF07690 Major Facilitator Superfamily 14 360 6.8E-22 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS02650 e078191e2e506e83738203550b636241 423 Gene3D G3DSA:1.20.1250.20 1 208 5.1E-21 T 29-03-2018 MC49_RS02650 e078191e2e506e83738203550b636241 423 SUPERFAMILY SSF103473 4 409 2.22E-42 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS00030 e1885aafb4235a7a1e26b5d6bcba8ef4 704 Gene3D G3DSA:3.40.50.300 478 703 4.2E-59 T 29-03-2018 MC49_RS00030 e1885aafb4235a7a1e26b5d6bcba8ef4 704 SUPERFAMILY SSF90123 164 476 1.83E-55 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MC49_RS00030 e1885aafb4235a7a1e26b5d6bcba8ef4 704 SUPERFAMILY SSF52540 487 699 3.62E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS00030 e1885aafb4235a7a1e26b5d6bcba8ef4 704 SMART SM00382 518 702 8.5E-19 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS00030 e1885aafb4235a7a1e26b5d6bcba8ef4 704 Pfam PF03412 Peptidase C39 family 21 148 9.3E-37 T 29-03-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 MC49_RS00030 e1885aafb4235a7a1e26b5d6bcba8ef4 704 Gene3D G3DSA:3.90.70.10 22 155 1.0E-37 T 29-03-2018 MC49_RS00030 e1885aafb4235a7a1e26b5d6bcba8ef4 704 Pfam PF00005 ABC transporter 510 658 1.5E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS00030 e1885aafb4235a7a1e26b5d6bcba8ef4 704 Gene3D G3DSA:1.20.1560.10 156 477 1.8E-38 T 29-03-2018 MC49_RS00030 e1885aafb4235a7a1e26b5d6bcba8ef4 704 Pfam PF00664 ABC transporter transmembrane region 177 443 6.7E-44 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MC49_RS00030 e1885aafb4235a7a1e26b5d6bcba8ef4 704 ProSitePatterns PS00211 ABC transporters family signature. 630 644 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS08775 f23d9c2ebd41a8007b5d2d1d93d33a04 405 Gene3D G3DSA:3.40.630.10 5 286 5.1E-49 T 29-03-2018 MC49_RS08775 f23d9c2ebd41a8007b5d2d1d93d33a04 405 SUPERFAMILY SSF53187 8 185 1.34E-53 T 29-03-2018 MC49_RS08775 f23d9c2ebd41a8007b5d2d1d93d33a04 405 SUPERFAMILY SSF53187 316 398 1.34E-53 T 29-03-2018 MC49_RS08775 f23d9c2ebd41a8007b5d2d1d93d33a04 405 SUPERFAMILY SSF55031 186 282 8.37E-13 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain MC49_RS08775 f23d9c2ebd41a8007b5d2d1d93d33a04 405 Pfam PF07687 Peptidase dimerisation domain 183 289 3.0E-17 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain MC49_RS08775 f23d9c2ebd41a8007b5d2d1d93d33a04 405 TIGRFAM TIGR03526 selenium_YgeY: putative selenium metabolism hydrolase 7 400 1.7E-218 T 29-03-2018 IPR017706 Peptidase M20/DapE, YgeY MC49_RS08775 f23d9c2ebd41a8007b5d2d1d93d33a04 405 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 76 85 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 MC49_RS08775 f23d9c2ebd41a8007b5d2d1d93d33a04 405 Pfam PF01546 Peptidase family M20/M25/M40 78 395 8.7E-24 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 MC49_RS01485 5d881d468a824d97ab9f04459d8d6625 598 PIRSF PIRSF000207 1 598 1.9E-245 T 29-03-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MC49_RS01485 5d881d468a824d97ab9f04459d8d6625 598 PRINTS PR00369 Flavodoxin signature 113 124 6.1E-11 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MC49_RS01485 5d881d468a824d97ab9f04459d8d6625 598 PRINTS PR00369 Flavodoxin signature 145 155 6.1E-11 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MC49_RS01485 5d881d468a824d97ab9f04459d8d6625 598 PRINTS PR00369 Flavodoxin signature 65 78 6.1E-11 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MC49_RS01485 5d881d468a824d97ab9f04459d8d6625 598 PRINTS PR00369 Flavodoxin signature 169 188 6.1E-11 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MC49_RS01485 5d881d468a824d97ab9f04459d8d6625 598 TIGRFAM TIGR01931 cysJ: sulfite reductase [NADPH] flavoprotein, alpha-component 9 598 1.5E-244 T 29-03-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MC49_RS01485 5d881d468a824d97ab9f04459d8d6625 598 SUPERFAMILY SSF63380 228 445 2.22E-63 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MC49_RS01485 5d881d468a824d97ab9f04459d8d6625 598 Pfam PF00175 Oxidoreductase NAD-binding domain 456 558 7.0E-19 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MC49_RS01485 5d881d468a824d97ab9f04459d8d6625 598 Gene3D G3DSA:2.40.30.10 220 438 8.0E-46 T 29-03-2018 MC49_RS01485 5d881d468a824d97ab9f04459d8d6625 598 Pfam PF00258 Flavodoxin 66 190 1.4E-26 T 29-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 MC49_RS01485 5d881d468a824d97ab9f04459d8d6625 598 Gene3D G3DSA:3.40.50.80 441 597 8.5E-35 T 29-03-2018 MC49_RS01485 5d881d468a824d97ab9f04459d8d6625 598 Gene3D G3DSA:3.40.50.360 43 210 2.2E-36 T 29-03-2018 IPR029039 Flavoprotein-like domain MC49_RS01485 5d881d468a824d97ab9f04459d8d6625 598 Pfam PF00667 FAD binding domain 231 423 2.9E-27 T 29-03-2018 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 MC49_RS01485 5d881d468a824d97ab9f04459d8d6625 598 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 493 504 4.3E-27 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MC49_RS01485 5d881d468a824d97ab9f04459d8d6625 598 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 385 392 4.3E-27 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MC49_RS01485 5d881d468a824d97ab9f04459d8d6625 598 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 480 489 4.3E-27 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MC49_RS01485 5d881d468a824d97ab9f04459d8d6625 598 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 455 474 4.3E-27 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MC49_RS01485 5d881d468a824d97ab9f04459d8d6625 598 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 524 540 4.3E-27 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MC49_RS01485 5d881d468a824d97ab9f04459d8d6625 598 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 547 555 4.3E-27 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MC49_RS01485 5d881d468a824d97ab9f04459d8d6625 598 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 269 279 4.3E-27 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MC49_RS01485 5d881d468a824d97ab9f04459d8d6625 598 SUPERFAMILY SSF52343 443 598 3.67E-50 T 29-03-2018 MC49_RS01485 5d881d468a824d97ab9f04459d8d6625 598 SUPERFAMILY SSF52218 64 207 8.59E-41 T 29-03-2018 IPR029039 Flavoprotein-like domain MC49_RS11845 ef19d9b712597fdf0f38652113a9b6f7 252 Gene3D G3DSA:2.40.50.140 1 76 3.0E-26 T 29-03-2018 MC49_RS11845 ef19d9b712597fdf0f38652113a9b6f7 252 Pfam PF11967 Recombination protein O N terminal 4 76 4.4E-24 T 29-03-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal MC49_RS11845 ef19d9b712597fdf0f38652113a9b6f7 252 TIGRFAM TIGR00613 reco: DNA repair protein RecO 5 230 1.7E-39 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 MC49_RS11845 ef19d9b712597fdf0f38652113a9b6f7 252 Hamap MF_00201 DNA repair protein RecO [recO]. 1 231 23.217 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 MC49_RS11845 ef19d9b712597fdf0f38652113a9b6f7 252 SUPERFAMILY SSF50249 4 75 6.85E-15 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS11845 ef19d9b712597fdf0f38652113a9b6f7 252 Pfam PF02565 Recombination protein O C terminal 83 226 1.5E-20 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 MC49_RS11845 ef19d9b712597fdf0f38652113a9b6f7 252 SUPERFAMILY SSF57863 86 167 7.32E-9 T 29-03-2018 MC49_RS13675 1f9315798b7419eef1ea15f914f2a2c1 127 SUPERFAMILY SSF81296 29 127 3.92E-26 T 29-03-2018 IPR014756 Immunoglobulin E-set MC49_RS13675 1f9315798b7419eef1ea15f914f2a2c1 127 Gene3D G3DSA:2.60.40.1220 29 127 1.0E-27 T 29-03-2018 MC49_RS13675 1f9315798b7419eef1ea15f914f2a2c1 127 Pfam PF04234 CopC domain 30 126 1.7E-22 T 29-03-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 MC49_RS18930 746af378c948121709acfe4f31753c6b 506 SUPERFAMILY SSF103473 475 501 4.05E-69 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS18930 746af378c948121709acfe4f31753c6b 506 SUPERFAMILY SSF103473 5 193 4.05E-69 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS18930 746af378c948121709acfe4f31753c6b 506 SUPERFAMILY SSF103473 251 423 4.05E-69 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS18930 746af378c948121709acfe4f31753c6b 506 Gene3D G3DSA:1.20.1250.20 11 199 6.4E-32 T 29-03-2018 MC49_RS18930 746af378c948121709acfe4f31753c6b 506 Gene3D G3DSA:1.20.1250.20 255 506 3.0E-30 T 29-03-2018 MC49_RS18930 746af378c948121709acfe4f31753c6b 506 Pfam PF07690 Major Facilitator Superfamily 20 413 1.1E-50 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS18930 746af378c948121709acfe4f31753c6b 506 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 14 498 2.9E-188 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 MC49_RS03285 4907fbd63e9979e34f173069f2fbfe9f 83 SUPERFAMILY SSF159871 5 83 1.83E-22 T 29-03-2018 IPR010854 Domain of unknown function DUF1471 MC49_RS03285 4907fbd63e9979e34f173069f2fbfe9f 83 Gene3D G3DSA:3.30.1660.10 21 83 5.7E-20 T 29-03-2018 IPR025543 Dodecin-like MC49_RS03285 4907fbd63e9979e34f173069f2fbfe9f 83 Pfam PF07338 Protein of unknown function (DUF1471) 33 83 3.1E-18 T 29-03-2018 IPR010854 Domain of unknown function DUF1471 MC49_RS00055 d68852c938d58d97233b503b1366f367 327 Pfam PF00107 Zinc-binding dehydrogenase 158 271 4.7E-9 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MC49_RS00055 d68852c938d58d97233b503b1366f367 327 SUPERFAMILY SSF51735 115 290 1.68E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS00055 d68852c938d58d97233b503b1366f367 327 SMART SM00829 12 323 3.7E-7 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MC49_RS00055 d68852c938d58d97233b503b1366f367 327 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 5 325 4.7E-130 T 29-03-2018 IPR014188 Acrylyl-CoA reductase AcuI MC49_RS00055 d68852c938d58d97233b503b1366f367 327 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 88 7.6E-6 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MC49_RS00055 d68852c938d58d97233b503b1366f367 327 Gene3D G3DSA:3.40.50.720 140 293 2.8E-18 T 29-03-2018 MC49_RS00055 d68852c938d58d97233b503b1366f367 327 Gene3D G3DSA:3.90.180.10 3 139 2.7E-25 T 29-03-2018 MC49_RS00055 d68852c938d58d97233b503b1366f367 327 SUPERFAMILY SSF50129 6 143 3.2E-41 T 29-03-2018 IPR011032 GroES-like MC49_RS17260 8417ac1f36d0de954c4e6b9c24c821a8 184 Gene3D G3DSA:3.90.1720.10 60 184 2.6E-38 T 29-03-2018 MC49_RS17260 8417ac1f36d0de954c4e6b9c24c821a8 184 Pfam PF00877 NlpC/P60 family 77 180 7.7E-31 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain MC49_RS17260 8417ac1f36d0de954c4e6b9c24c821a8 184 SUPERFAMILY SSF54001 65 183 1.96E-38 T 29-03-2018 MC49_RS11015 8b906392ba184c1da525960570cc6011 369 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 37 361 3.2E-57 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MC49_RS11015 8b906392ba184c1da525960570cc6011 369 Gene3D G3DSA:2.40.50.100 178 350 1.9E-7 T 29-03-2018 MC49_RS11015 8b906392ba184c1da525960570cc6011 369 SUPERFAMILY SSF111369 51 296 2.62E-29 T 29-03-2018 MC49_RS11015 8b906392ba184c1da525960570cc6011 369 Gene3D G3DSA:2.40.50.100 59 123 1.1E-17 T 29-03-2018 MC49_RS11015 8b906392ba184c1da525960570cc6011 369 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 45 293 9.1E-24 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MC49_RS11015 8b906392ba184c1da525960570cc6011 369 Gene3D G3DSA:1.10.287.470 124 177 6.3E-10 T 29-03-2018 MC49_RS12775 0fc85cebc5a12356c957f135dab44815 255 SUPERFAMILY SSF53850 3 249 1.43E-63 T 29-03-2018 MC49_RS12775 0fc85cebc5a12356c957f135dab44815 255 Gene3D G3DSA:3.40.190.10 136 250 3.5E-16 T 29-03-2018 MC49_RS12775 0fc85cebc5a12356c957f135dab44815 255 SMART SM00079 25 247 5.9E-6 T 29-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 MC49_RS12775 0fc85cebc5a12356c957f135dab44815 255 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 27 246 3.8E-59 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MC49_RS12775 0fc85cebc5a12356c957f135dab44815 255 Gene3D G3DSA:3.40.190.10 16 135 9.4E-33 T 29-03-2018 MC49_RS12775 0fc85cebc5a12356c957f135dab44815 255 SMART SM00062 25 248 7.7E-57 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MC49_RS15655 72083227cd8aef28ccf28a7975ba5c9e 424 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 2 424 5.4E-139 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MC49_RS15655 72083227cd8aef28ccf28a7975ba5c9e 424 Pfam PF00579 tRNA synthetases class I (W and Y) 31 328 1.5E-87 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS15655 72083227cd8aef28ccf28a7975ba5c9e 424 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 52 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS15655 72083227cd8aef28ccf28a7975ba5c9e 424 Gene3D G3DSA:3.40.50.620 1 227 1.7E-69 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS15655 72083227cd8aef28ccf28a7975ba5c9e 424 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 4 423 45.692 T 29-03-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 MC49_RS15655 72083227cd8aef28ccf28a7975ba5c9e 424 Pfam PF01479 S4 domain 359 402 6.3E-5 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MC49_RS15655 72083227cd8aef28ccf28a7975ba5c9e 424 SMART SM00363 357 419 0.0023 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MC49_RS15655 72083227cd8aef28ccf28a7975ba5c9e 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 188 210 1.0E-31 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MC49_RS15655 72083227cd8aef28ccf28a7975ba5c9e 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 46 68 1.0E-31 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MC49_RS15655 72083227cd8aef28ccf28a7975ba5c9e 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 167 182 1.0E-31 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MC49_RS15655 72083227cd8aef28ccf28a7975ba5c9e 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 221 233 1.0E-31 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MC49_RS15655 72083227cd8aef28ccf28a7975ba5c9e 424 Gene3D G3DSA:3.10.290.10 331 424 2.3E-20 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MC49_RS15655 72083227cd8aef28ccf28a7975ba5c9e 424 Gene3D G3DSA:1.10.240.10 228 330 6.8E-32 T 29-03-2018 MC49_RS15655 72083227cd8aef28ccf28a7975ba5c9e 424 SUPERFAMILY SSF55174 327 423 1.44E-20 T 29-03-2018 MC49_RS15655 72083227cd8aef28ccf28a7975ba5c9e 424 SUPERFAMILY SSF52374 5 328 1.21E-105 T 29-03-2018 MC49_RS18480 6af0079bc61fab7ffd8df0e8d496f1a1 201 Gene3D G3DSA:3.40.50.10420 1 199 1.1E-59 T 29-03-2018 MC49_RS18480 6af0079bc61fab7ffd8df0e8d496f1a1 201 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 12 191 1.2E-46 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase MC49_RS18480 6af0079bc61fab7ffd8df0e8d496f1a1 201 SUPERFAMILY SSF100950 10 198 4.6E-57 T 29-03-2018 MC49_RS18480 6af0079bc61fab7ffd8df0e8d496f1a1 201 PIRSF PIRSF006806 6 194 9.1E-43 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase MC49_RS18480 6af0079bc61fab7ffd8df0e8d496f1a1 201 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 11 191 1.7E-57 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase MC49_RS08235 4fd5f4470ad575c7d7ff964426dba0cf 348 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 75 88 - T 29-03-2018 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Reactome: R-HSA-6782315 MC49_RS08235 4fd5f4470ad575c7d7ff964426dba0cf 348 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 7 172 1.7E-44 T 29-03-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS08235 4fd5f4470ad575c7d7ff964426dba0cf 348 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 189 335 1.4E-15 T 29-03-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS08235 4fd5f4470ad575c7d7ff964426dba0cf 348 TIGRFAM TIGR00094 tRNA_TruD_broad: tRNA pseudouridine synthase, TruD family 8 340 1.7E-77 T 29-03-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS08235 4fd5f4470ad575c7d7ff964426dba0cf 348 Gene3D G3DSA:3.30.2340.10 165 300 2.3E-27 T 29-03-2018 MC49_RS08235 4fd5f4470ad575c7d7ff964426dba0cf 348 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 3 340 28.451 T 29-03-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS08235 4fd5f4470ad575c7d7ff964426dba0cf 348 SUPERFAMILY SSF55120 6 337 4.89E-99 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS16955 e97529995fe6420faba55ff51a534eed 224 SMART SM00862 145 220 6.4E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MC49_RS16955 e97529995fe6420faba55ff51a534eed 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 220 1.6E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MC49_RS16955 e97529995fe6420faba55ff51a534eed 224 SUPERFAMILY SSF52172 1 179 8.11E-36 T 29-03-2018 IPR011006 CheY-like superfamily MC49_RS16955 e97529995fe6420faba55ff51a534eed 224 Gene3D G3DSA:3.40.50.2300 1 121 6.3E-32 T 29-03-2018 MC49_RS16955 e97529995fe6420faba55ff51a534eed 224 Pfam PF00072 Response regulator receiver domain 3 112 4.4E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS16955 e97529995fe6420faba55ff51a534eed 224 Gene3D G3DSA:1.10.10.10 122 224 6.5E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS16955 e97529995fe6420faba55ff51a534eed 224 SMART SM00448 1 112 7.4E-34 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS13045 f3fc83c2eafc3019e58f872d40561e91 90 Gene3D G3DSA:1.10.3100.10 1 86 2.8E-21 T 29-03-2018 IPR027910 YdiL-like domain MC49_RS13045 f3fc83c2eafc3019e58f872d40561e91 90 Pfam PF01381 Helix-turn-helix 12 66 5.3E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS13045 f3fc83c2eafc3019e58f872d40561e91 90 SMART SM00530 11 66 7.6E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS13045 f3fc83c2eafc3019e58f872d40561e91 90 SUPERFAMILY SSF47413 3 78 1.21E-19 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS03875 afb74accaa2cb229540d28c35bb5f8ad 491 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 35 204 2.9E-57 T 29-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MC49_RS03875 afb74accaa2cb229540d28c35bb5f8ad 491 SUPERFAMILY SSF48179 210 367 5.27E-41 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MC49_RS03875 afb74accaa2cb229540d28c35bb5f8ad 491 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 210 341 1.3E-28 T 29-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MC49_RS03875 afb74accaa2cb229540d28c35bb5f8ad 491 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 354 482 4.3E-22 T 29-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MC49_RS03875 afb74accaa2cb229540d28c35bb5f8ad 491 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 22 485 38.768 T 29-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MC49_RS03875 afb74accaa2cb229540d28c35bb5f8ad 491 Gene3D G3DSA:1.10.1040.10 210 487 8.2E-89 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MC49_RS03875 afb74accaa2cb229540d28c35bb5f8ad 491 SUPERFAMILY SSF48179 348 484 2.55E-40 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MC49_RS03875 afb74accaa2cb229540d28c35bb5f8ad 491 Gene3D G3DSA:3.40.50.720 1 42 6.6E-4 T 29-03-2018 MC49_RS03875 afb74accaa2cb229540d28c35bb5f8ad 491 Gene3D G3DSA:3.40.50.720 56 208 1.4E-50 T 29-03-2018 MC49_RS03875 afb74accaa2cb229540d28c35bb5f8ad 491 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 35 367 2.7E-131 T 29-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MC49_RS03875 afb74accaa2cb229540d28c35bb5f8ad 491 SUPERFAMILY SSF51735 29 209 1.58E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS10875 87bdfc963c5c4b69cbc9ca31f8cc787d 259 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 256 6.7E-111 T 29-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 MC49_RS10875 87bdfc963c5c4b69cbc9ca31f8cc787d 259 Gene3D G3DSA:3.20.20.70 4 252 2.1E-59 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS10875 87bdfc963c5c4b69cbc9ca31f8cc787d 259 SUPERFAMILY SSF51366 1 256 5.89E-74 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MC49_RS10875 87bdfc963c5c4b69cbc9ca31f8cc787d 259 Pfam PF00977 Histidine biosynthesis protein 5 239 1.8E-79 T 29-03-2018 IPR006062 Histidine biosynthesis GO:0000105 MC49_RS10875 87bdfc963c5c4b69cbc9ca31f8cc787d 259 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 256 44.028 T 29-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 MC49_RS15275 96ece69661bd172fb8df5a33672132f7 324 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 317 1.6E-25 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MC49_RS15275 96ece69661bd172fb8df5a33672132f7 324 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 298 1.8E-21 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MC49_RS15275 96ece69661bd172fb8df5a33672132f7 324 Gene3D G3DSA:3.40.50.300 1 324 5.1E-73 T 29-03-2018 MC49_RS15275 96ece69661bd172fb8df5a33672132f7 324 SUPERFAMILY SSF52540 34 306 9.13E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS15275 96ece69661bd172fb8df5a33672132f7 324 SMART SM00382 33 239 8.6E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS15275 96ece69661bd172fb8df5a33672132f7 324 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS15275 96ece69661bd172fb8df5a33672132f7 324 Pfam PF00005 ABC transporter 25 181 2.5E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS15870 bbb37f8e0e60ed6141725356a6676691 330 SUPERFAMILY SSF81345 7 325 1.57E-79 T 29-03-2018 IPR029022 ABC transporter, BtuC-like MC49_RS15870 bbb37f8e0e60ed6141725356a6676691 330 Pfam PF01032 FecCD transport family 17 326 2.8E-86 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 MC49_RS15870 bbb37f8e0e60ed6141725356a6676691 330 Gene3D G3DSA:1.10.3470.10 6 330 1.1E-70 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like MC49_RS02575 d056c820907a0015e7ff59ddeaa4a03f 423 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 5 401 2.3E-141 T 29-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 MC49_RS02575 d056c820907a0015e7ff59ddeaa4a03f 423 Pfam PF13393 Histidyl-tRNA synthetase 9 311 7.9E-49 T 29-03-2018 MC49_RS02575 d056c820907a0015e7ff59ddeaa4a03f 423 Gene3D G3DSA:3.30.930.10 1 325 2.2E-75 T 29-03-2018 MC49_RS02575 d056c820907a0015e7ff59ddeaa4a03f 423 PIRSF PIRSF001549 1 418 5.2E-114 T 29-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 MC49_RS02575 d056c820907a0015e7ff59ddeaa4a03f 423 SUPERFAMILY SSF52954 326 415 9.81E-8 T 29-03-2018 IPR004154 Anticodon-binding MC49_RS02575 d056c820907a0015e7ff59ddeaa4a03f 423 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 2 416 30.454 T 29-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 MC49_RS02575 d056c820907a0015e7ff59ddeaa4a03f 423 SUPERFAMILY SSF55681 3 322 5.55E-105 T 29-03-2018 MC49_RS04330 5bd32e22a5f52b9f914c873c8ddf4e63 230 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 20 140 3.0E-41 T 29-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 MC49_RS04330 5bd32e22a5f52b9f914c873c8ddf4e63 230 Gene3D G3DSA:2.60.40.10 21 138 1.3E-37 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS04330 5bd32e22a5f52b9f914c873c8ddf4e63 230 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 163 222 1.2E-13 T 29-03-2018 IPR016148 Pili assembly chaperone, C-terminal MC49_RS04330 5bd32e22a5f52b9f914c873c8ddf4e63 230 ProSitePatterns PS00635 Gram-negative pili assembly chaperone signature. 97 114 - T 29-03-2018 IPR018046 Pili assembly chaperone, conserved site MC49_RS04330 5bd32e22a5f52b9f914c873c8ddf4e63 230 SUPERFAMILY SSF49354 17 140 8.63E-41 T 29-03-2018 IPR008962 PapD-like MC49_RS04330 5bd32e22a5f52b9f914c873c8ddf4e63 230 PRINTS PR00969 Pili chaperone signature 70 91 2.1E-32 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS04330 5bd32e22a5f52b9f914c873c8ddf4e63 230 PRINTS PR00969 Pili chaperone signature 122 137 2.1E-32 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS04330 5bd32e22a5f52b9f914c873c8ddf4e63 230 PRINTS PR00969 Pili chaperone signature 21 30 2.1E-32 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS04330 5bd32e22a5f52b9f914c873c8ddf4e63 230 PRINTS PR00969 Pili chaperone signature 157 172 2.1E-32 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS04330 5bd32e22a5f52b9f914c873c8ddf4e63 230 PRINTS PR00969 Pili chaperone signature 98 115 2.1E-32 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS04330 5bd32e22a5f52b9f914c873c8ddf4e63 230 Gene3D G3DSA:2.60.40.10 142 229 1.8E-16 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS04330 5bd32e22a5f52b9f914c873c8ddf4e63 230 SUPERFAMILY SSF49584 134 226 9.42E-17 T 29-03-2018 IPR016148 Pili assembly chaperone, C-terminal MC49_RS00535 b49e4932548e8583fc9e0db06cc7bde5 138 Gene3D G3DSA:1.10.1660.10 1 55 4.1E-21 T 29-03-2018 MC49_RS00535 b49e4932548e8583fc9e0db06cc7bde5 138 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 7.1E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MC49_RS00535 b49e4932548e8583fc9e0db06cc7bde5 138 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 7.1E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MC49_RS00535 b49e4932548e8583fc9e0db06cc7bde5 138 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 7.1E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MC49_RS00535 b49e4932548e8583fc9e0db06cc7bde5 138 SUPERFAMILY SSF46955 1 126 3.48E-34 T 29-03-2018 IPR009061 Putative DNA-binding domain MC49_RS00535 b49e4932548e8583fc9e0db06cc7bde5 138 SMART SM00422 1 70 1.5E-28 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MC49_RS00535 b49e4932548e8583fc9e0db06cc7bde5 138 TIGRFAM TIGR02044 CueR: Cu(I)-responsive transcriptional regulator 1 126 9.8E-53 T 29-03-2018 IPR011789 Cu(I)-responsive transcriptional regulator GO:0003677|GO:0003700|GO:0005507|GO:0045893 MC49_RS00535 b49e4932548e8583fc9e0db06cc7bde5 138 Pfam PF13411 MerR HTH family regulatory protein 1 68 8.1E-19 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MC49_RS00535 b49e4932548e8583fc9e0db06cc7bde5 138 Gene3D G3DSA:1.10.1660.10 56 136 2.7E-16 T 29-03-2018 MC49_RS04180 b42499d0f3ded7e1abb57dd97fea9894 394 PRINTS PR00315 GTP-binding elongation factor signature 58 66 2.9E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS04180 b42499d0f3ded7e1abb57dd97fea9894 394 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.9E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS04180 b42499d0f3ded7e1abb57dd97fea9894 394 PRINTS PR00315 GTP-binding elongation factor signature 131 140 2.9E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS04180 b42499d0f3ded7e1abb57dd97fea9894 394 PRINTS PR00315 GTP-binding elongation factor signature 94 105 2.9E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS04180 b42499d0f3ded7e1abb57dd97fea9894 394 PRINTS PR00315 GTP-binding elongation factor signature 78 88 2.9E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS04180 b42499d0f3ded7e1abb57dd97fea9894 394 Gene3D G3DSA:3.40.50.300 2 74 4.0E-11 T 29-03-2018 MC49_RS04180 b42499d0f3ded7e1abb57dd97fea9894 394 Pfam PF03143 Elongation factor Tu C-terminal domain 298 392 8.2E-34 T 29-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal MC49_RS04180 b42499d0f3ded7e1abb57dd97fea9894 394 Gene3D G3DSA:2.40.30.10 206 299 1.3E-32 T 29-03-2018 MC49_RS04180 b42499d0f3ded7e1abb57dd97fea9894 394 Gene3D G3DSA:2.40.30.10 300 393 8.2E-33 T 29-03-2018 MC49_RS04180 b42499d0f3ded7e1abb57dd97fea9894 394 Pfam PF00009 Elongation factor Tu GTP binding domain 10 201 7.6E-58 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS04180 b42499d0f3ded7e1abb57dd97fea9894 394 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 393 1.6E-238 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MC49_RS04180 b42499d0f3ded7e1abb57dd97fea9894 394 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 394 60.995 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MC49_RS04180 b42499d0f3ded7e1abb57dd97fea9894 394 SUPERFAMILY SSF52540 6 219 2.41E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS04180 b42499d0f3ded7e1abb57dd97fea9894 394 Pfam PF03144 Elongation factor Tu domain 2 225 293 1.9E-17 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MC49_RS04180 b42499d0f3ded7e1abb57dd97fea9894 394 Gene3D G3DSA:3.40.50.300 75 203 1.9E-30 T 29-03-2018 MC49_RS04180 b42499d0f3ded7e1abb57dd97fea9894 394 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 148 2.0E-14 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MC49_RS04180 b42499d0f3ded7e1abb57dd97fea9894 394 SUPERFAMILY SSF50465 298 393 3.45E-36 T 29-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal MC49_RS04180 b42499d0f3ded7e1abb57dd97fea9894 394 SUPERFAMILY SSF50447 205 301 3.53E-30 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain MC49_RS04180 b42499d0f3ded7e1abb57dd97fea9894 394 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site MC49_RS02460 ec7e64dd499acb2cb7cef6a2cfc2fc66 187 Pfam PF00589 Phage integrase family 5 174 8.2E-42 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MC49_RS02460 ec7e64dd499acb2cb7cef6a2cfc2fc66 187 SUPERFAMILY SSF56349 4 185 3.83E-43 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MC49_RS02460 ec7e64dd499acb2cb7cef6a2cfc2fc66 187 Gene3D G3DSA:1.10.443.10 5 182 4.7E-36 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MC49_RS13925 550e9bb4b039b2b9de97042ba8d06e42 278 Gene3D G3DSA:1.10.8.10 1 84 1.6E-22 T 29-03-2018 MC49_RS13925 550e9bb4b039b2b9de97042ba8d06e42 278 Gene3D G3DSA:3.40.50.150 85 276 1.7E-45 T 29-03-2018 MC49_RS13925 550e9bb4b039b2b9de97042ba8d06e42 278 SUPERFAMILY SSF53335 4 273 2.76E-61 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS13925 550e9bb4b039b2b9de97042ba8d06e42 278 Pfam PF13847 Methyltransferase domain 110 250 4.7E-21 T 29-03-2018 IPR025714 Methyltransferase domain MC49_RS13925 550e9bb4b039b2b9de97042ba8d06e42 278 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 180 186 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MC49_RS13925 550e9bb4b039b2b9de97042ba8d06e42 278 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 3 275 45.421 T 29-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 MC49_RS13925 550e9bb4b039b2b9de97042ba8d06e42 278 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 3 276 1.2E-87 T 29-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 MC49_RS13925 550e9bb4b039b2b9de97042ba8d06e42 278 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 23 271 1.6E-91 T 29-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 MC49_RS10925 205556d990fe7ba5f78586b2b6be3209 400 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 285 376 1.0E-25 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MC49_RS10925 205556d990fe7ba5f78586b2b6be3209 400 Gene3D G3DSA:2.60.410.10 303 376 2.4E-19 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MC49_RS10925 205556d990fe7ba5f78586b2b6be3209 400 SUPERFAMILY SSF56601 16 285 1.1E-78 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MC49_RS10925 205556d990fe7ba5f78586b2b6be3209 400 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 32 265 2.2E-94 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 MC49_RS10925 205556d990fe7ba5f78586b2b6be3209 400 SMART SM00936 285 376 2.9E-33 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MC49_RS10925 205556d990fe7ba5f78586b2b6be3209 400 SUPERFAMILY SSF69189 285 378 5.69E-25 T 29-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MC49_RS10925 205556d990fe7ba5f78586b2b6be3209 400 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 124 141 1.4E-17 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MC49_RS10925 205556d990fe7ba5f78586b2b6be3209 400 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 151 164 1.4E-17 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MC49_RS10925 205556d990fe7ba5f78586b2b6be3209 400 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 65 76 1.4E-17 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MC49_RS10925 205556d990fe7ba5f78586b2b6be3209 400 Gene3D G3DSA:3.40.710.10 24 302 4.7E-51 T 29-03-2018 MC49_RS14400 5fab1352256c4ffb4bbe172b2b3a5416 336 SUPERFAMILY SSF51735 119 295 2.45E-54 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS14400 5fab1352256c4ffb4bbe172b2b3a5416 336 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 10 331 5.0E-142 T 29-03-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 MC49_RS14400 5fab1352256c4ffb4bbe172b2b3a5416 336 SUPERFAMILY SSF50129 10 147 1.31E-33 T 29-03-2018 IPR011032 GroES-like MC49_RS14400 5fab1352256c4ffb4bbe172b2b3a5416 336 Pfam PF00107 Zinc-binding dehydrogenase 159 276 1.9E-32 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MC49_RS14400 5fab1352256c4ffb4bbe172b2b3a5416 336 Gene3D G3DSA:3.40.50.720 141 317 2.2E-44 T 29-03-2018 MC49_RS14400 5fab1352256c4ffb4bbe172b2b3a5416 336 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 39 108 8.4E-9 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MC49_RS14400 5fab1352256c4ffb4bbe172b2b3a5416 336 Gene3D G3DSA:3.90.180.10 6 140 1.2E-35 T 29-03-2018 MC49_RS14400 5fab1352256c4ffb4bbe172b2b3a5416 336 SMART SM00829 19 331 1.3E-52 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MC49_RS04660 800222bb62e524846f89742380781716 205 Gene3D G3DSA:3.30.70.20 20 80 2.9E-15 T 29-03-2018 MC49_RS04660 800222bb62e524846f89742380781716 205 Gene3D G3DSA:3.30.70.20 2 19 0.0038 T 29-03-2018 MC49_RS04660 800222bb62e524846f89742380781716 205 Gene3D G3DSA:3.30.70.20 120 197 8.1E-16 T 29-03-2018 MC49_RS04660 800222bb62e524846f89742380781716 205 SUPERFAMILY SSF54862 3 198 1.26E-69 T 29-03-2018 MC49_RS04660 800222bb62e524846f89742380781716 205 TIGRFAM TIGR02951 DMSO_dmsB: dimethylsulfoxide reductase, chain B 4 163 4.7E-78 T 29-03-2018 IPR014297 Dimethylsulphoxide reductase, chain B MC49_RS04660 800222bb62e524846f89742380781716 205 Gene3D G3DSA:3.30.70.20 81 119 5.3E-21 T 29-03-2018 MC49_RS04660 800222bb62e524846f89742380781716 205 Pfam PF13247 4Fe-4S dicluster domain 59 153 5.8E-28 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MC49_RS04660 800222bb62e524846f89742380781716 205 Pfam PF12800 4Fe-4S binding domain 12 25 0.0023 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MC49_RS04660 800222bb62e524846f89742380781716 205 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 99 110 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MC49_RS06290 f84c811282cf46951f9071dc3b928ff4 72 Pfam PF06794 Uncharacterised protein family (UPF0270) 1 68 2.0E-30 T 29-03-2018 IPR010648 Uncharacterised protein family UPF0270 MC49_RS06290 f84c811282cf46951f9071dc3b928ff4 72 PIRSF PIRSF006169 1 72 6.3E-33 T 29-03-2018 IPR010648 Uncharacterised protein family UPF0270 MC49_RS06290 f84c811282cf46951f9071dc3b928ff4 72 Hamap MF_00690 UPF0270 protein YheU [yheU]. 1 70 22.683 T 29-03-2018 IPR010648 Uncharacterised protein family UPF0270 MC49_RS06290 f84c811282cf46951f9071dc3b928ff4 72 Gene3D G3DSA:1.10.10.610 1 71 2.1E-30 T 29-03-2018 IPR010648 Uncharacterised protein family UPF0270 MC49_RS06290 f84c811282cf46951f9071dc3b928ff4 72 SUPERFAMILY SSF118001 1 70 3.14E-25 T 29-03-2018 IPR010648 Uncharacterised protein family UPF0270 MC49_RS06290 f84c811282cf46951f9071dc3b928ff4 72 ProDom PD026997 UPF0270 YHEU SO0879 3D-STRUCTURE LYASE PLU0398 YPO0179/Y3960/YP0178 ENOLASE HD0737 PSPTO1630 1 67 1.0E-22 T 29-03-2018 IPR010648 Uncharacterised protein family UPF0270 MC49_RS17700 bf1c9d79662dd4c4009cbda421aea315 63 Pfam PF16080 Bacteriophage holin family HP1 5 59 4.7E-29 T 29-03-2018 IPR032118 Bacteriophage holin HP1 family MC49_RS06810 bf1c9d79662dd4c4009cbda421aea315 63 Pfam PF16080 Bacteriophage holin family HP1 5 59 4.7E-29 T 29-03-2018 IPR032118 Bacteriophage holin HP1 family MC49_RS18990 844760a8dde81b0c56e05ad7324483d6 446 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 9 442 63.183 T 29-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 MC49_RS18990 844760a8dde81b0c56e05ad7324483d6 446 SUPERFAMILY SSF102114 113 372 4.45E-54 T 29-03-2018 MC49_RS18990 844760a8dde81b0c56e05ad7324483d6 446 Pfam PF04055 Radical SAM superfamily 147 324 3.9E-31 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MC49_RS18990 844760a8dde81b0c56e05ad7324483d6 446 SMART SM00729 141 366 1.1E-53 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MC49_RS18990 844760a8dde81b0c56e05ad7324483d6 446 Gene3D G3DSA:3.80.30.20 138 380 7.2E-48 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe MC49_RS18990 844760a8dde81b0c56e05ad7324483d6 446 Gene3D G3DSA:2.40.50.140 381 445 7.2E-22 T 29-03-2018 MC49_RS18990 844760a8dde81b0c56e05ad7324483d6 446 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 10 440 7.2E-110 T 29-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 MC49_RS18990 844760a8dde81b0c56e05ad7324483d6 446 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 10 440 8.5E-194 T 29-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 MC49_RS18990 844760a8dde81b0c56e05ad7324483d6 446 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 145 165 - T 29-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 MC49_RS18990 844760a8dde81b0c56e05ad7324483d6 446 Pfam PF00919 Uncharacterized protein family UPF0004 10 96 8.5E-22 T 29-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 SMART SM00433 35 625 1.2E-208 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 SUPERFAMILY SSF55874 6 216 1.23E-69 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 SUPERFAMILY SSF54211 218 383 3.98E-45 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 Pfam PF01751 Toprim domain 414 521 7.6E-13 T 29-03-2018 IPR006171 TOPRIM domain MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 PRINTS PR00418 DNA topoisomerase II family signature 267 280 7.5E-59 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 PRINTS PR00418 DNA topoisomerase II family signature 561 577 7.5E-59 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 PRINTS PR00418 DNA topoisomerase II family signature 110 124 7.5E-59 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 PRINTS PR00418 DNA topoisomerase II family signature 518 530 7.5E-59 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 PRINTS PR00418 DNA topoisomerase II family signature 32 47 7.5E-59 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 PRINTS PR00418 DNA topoisomerase II family signature 67 80 7.5E-59 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 PRINTS PR00418 DNA topoisomerase II family signature 480 496 7.5E-59 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 PRINTS PR00418 DNA topoisomerase II family signature 498 515 7.5E-59 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 PRINTS PR00418 DNA topoisomerase II family signature 415 429 7.5E-59 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 557 621 3.7E-25 T 29-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 ProSitePatterns PS00177 DNA topoisomerase II signature. 417 425 - T 29-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 TIGRFAM TIGR01055 parE_Gneg: DNA topoisomerase IV, B subunit 5 627 0.0 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 Gene3D G3DSA:3.40.50.670 397 628 4.2E-80 T 29-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 SMART SM00387 28 174 8.1E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 Pfam PF00204 DNA gyrase B 219 385 1.5E-40 T 29-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 29 172 3.8E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 Hamap MF_00938 DNA topoisomerase 4 subunit B [parE]. 3 629 47.659 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 Gene3D G3DSA:3.30.230.10 218 392 7.9E-40 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 PRINTS PR01098 Topoisomerase IV subunit B signature 538 560 5.0E-144 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 PRINTS PR01098 Topoisomerase IV subunit B signature 504 520 5.0E-144 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 PRINTS PR01098 Topoisomerase IV subunit B signature 150 165 5.0E-144 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 PRINTS PR01098 Topoisomerase IV subunit B signature 470 482 5.0E-144 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 PRINTS PR01098 Topoisomerase IV subunit B signature 363 388 5.0E-144 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 PRINTS PR01098 Topoisomerase IV subunit B signature 136 150 5.0E-144 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 PRINTS PR01098 Topoisomerase IV subunit B signature 312 327 5.0E-144 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 PRINTS PR01098 Topoisomerase IV subunit B signature 295 311 5.0E-144 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 PRINTS PR01098 Topoisomerase IV subunit B signature 449 470 5.0E-144 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 PRINTS PR01098 Topoisomerase IV subunit B signature 193 214 5.0E-144 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 PRINTS PR01098 Topoisomerase IV subunit B signature 175 192 5.0E-144 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 PRINTS PR01098 Topoisomerase IV subunit B signature 27 40 5.0E-144 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 PRINTS PR01098 Topoisomerase IV subunit B signature 239 262 5.0E-144 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 PRINTS PR01098 Topoisomerase IV subunit B signature 339 362 5.0E-144 T 29-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 Gene3D G3DSA:3.30.565.10 18 217 7.3E-69 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS07745 31e91be75cd9d24b36a3d7d4b55767b3 631 SUPERFAMILY SSF56719 389 623 7.59E-79 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MC49_RS12080 bed3d60ad1f8e78af36e472b5ef3fce4 393 Gene3D G3DSA:1.10.490.10 1 157 9.7E-39 T 29-03-2018 MC49_RS12080 bed3d60ad1f8e78af36e472b5ef3fce4 393 PRINTS PR00410 Phenol hydroxylase reductase family signature 263 282 1.1E-9 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MC49_RS12080 bed3d60ad1f8e78af36e472b5ef3fce4 393 PRINTS PR00410 Phenol hydroxylase reductase family signature 355 363 1.1E-9 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MC49_RS12080 bed3d60ad1f8e78af36e472b5ef3fce4 393 PRINTS PR00410 Phenol hydroxylase reductase family signature 247 256 1.1E-9 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MC49_RS12080 bed3d60ad1f8e78af36e472b5ef3fce4 393 PRINTS PR00410 Phenol hydroxylase reductase family signature 183 195 1.1E-9 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MC49_RS12080 bed3d60ad1f8e78af36e472b5ef3fce4 393 Gene3D G3DSA:3.40.50.80 254 393 5.3E-24 T 29-03-2018 MC49_RS12080 bed3d60ad1f8e78af36e472b5ef3fce4 393 SUPERFAMILY SSF52343 257 391 1.14E-35 T 29-03-2018 MC49_RS12080 bed3d60ad1f8e78af36e472b5ef3fce4 393 SUPERFAMILY SSF63380 148 253 3.57E-28 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MC49_RS12080 bed3d60ad1f8e78af36e472b5ef3fce4 393 Pfam PF00970 Oxidoreductase FAD-binding domain 156 252 3.7E-8 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 MC49_RS12080 bed3d60ad1f8e78af36e472b5ef3fce4 393 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 204 211 4.3E-8 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MC49_RS12080 bed3d60ad1f8e78af36e472b5ef3fce4 393 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 183 193 4.3E-8 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MC49_RS12080 bed3d60ad1f8e78af36e472b5ef3fce4 393 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 263 282 4.3E-8 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MC49_RS12080 bed3d60ad1f8e78af36e472b5ef3fce4 393 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 355 363 4.3E-8 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MC49_RS12080 bed3d60ad1f8e78af36e472b5ef3fce4 393 SUPERFAMILY SSF46458 1 142 5.49E-38 T 29-03-2018 IPR009050 Globin-like MC49_RS12080 bed3d60ad1f8e78af36e472b5ef3fce4 393 Pfam PF00175 Oxidoreductase NAD-binding domain 264 369 5.0E-16 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MC49_RS12080 bed3d60ad1f8e78af36e472b5ef3fce4 393 Pfam PF00042 Globin 7 102 4.5E-13 T 29-03-2018 IPR000971 Globin GO:0020037 MC49_RS12080 bed3d60ad1f8e78af36e472b5ef3fce4 393 Gene3D G3DSA:2.40.30.10 158 253 1.6E-27 T 29-03-2018 MC49_RS12080 bed3d60ad1f8e78af36e472b5ef3fce4 393 Hamap MF_01252 Flavohemoprotein [hmp]. 1 393 54.702 T 29-03-2018 IPR023950 Flavohemoprotein GO:0008941|GO:0019825|GO:0020037|GO:0051409|GO:0055114|GO:0071949 MC49_RS10650 1b616d033b32269bc34fe183ebdbedc1 581 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS10650 1b616d033b32269bc34fe183ebdbedc1 581 Pfam PF00005 ABC transporter 24 165 5.5E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS10650 1b616d033b32269bc34fe183ebdbedc1 581 Pfam PF00005 ABC transporter 346 489 6.2E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS10650 1b616d033b32269bc34fe183ebdbedc1 581 SUPERFAMILY SSF52540 5 229 3.03E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS10650 1b616d033b32269bc34fe183ebdbedc1 581 SMART SM00382 354 535 5.1E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS10650 1b616d033b32269bc34fe183ebdbedc1 581 SMART SM00382 32 266 5.4E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS10650 1b616d033b32269bc34fe183ebdbedc1 581 SUPERFAMILY SSF52540 325 548 5.64E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS10650 1b616d033b32269bc34fe183ebdbedc1 581 Gene3D G3DSA:3.40.50.300 326 578 3.6E-62 T 29-03-2018 MC49_RS10650 1b616d033b32269bc34fe183ebdbedc1 581 Gene3D G3DSA:3.40.50.300 1 247 3.1E-52 T 29-03-2018 MC49_RS07645 e8d798c46209862d6c1afb57c2211de4 424 Gene3D G3DSA:1.20.5.170 188 303 0.036 T 29-03-2018 MC49_RS07645 e8d798c46209862d6c1afb57c2211de4 424 Pfam PF03895 YadA-like membrane anchor domain 365 424 1.5E-14 T 29-03-2018 IPR005594 YadA-like, C-terminal MC49_RS07645 e8d798c46209862d6c1afb57c2211de4 424 Gene3D G3DSA:1.20.120.330 90 186 0.0088 T 29-03-2018 MC49_RS07645 e8d798c46209862d6c1afb57c2211de4 424 SUPERFAMILY SSF54523 334 424 5.96E-19 T 29-03-2018 MC49_RS07645 e8d798c46209862d6c1afb57c2211de4 424 Gene3D G3DSA:3.30.1300.30 320 424 1.9E-25 T 29-03-2018 MC49_RS05520 f62134a6b0f3f1310212525da9892ec3 242 SUPERFAMILY SSF54211 3 185 3.69E-45 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MC49_RS05520 f62134a6b0f3f1310212525da9892ec3 242 Hamap MF_00564 Ribonuclease PH [rph]. 5 241 48.634 T 29-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 MC49_RS05520 f62134a6b0f3f1310212525da9892ec3 242 Pfam PF03725 3' exoribonuclease family, domain 2 162 226 1.6E-9 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MC49_RS05520 f62134a6b0f3f1310212525da9892ec3 242 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 6 240 9.0E-112 T 29-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 MC49_RS05520 f62134a6b0f3f1310212525da9892ec3 242 Gene3D G3DSA:3.30.230.70 1 242 2.1E-58 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MC49_RS05520 f62134a6b0f3f1310212525da9892ec3 242 SUPERFAMILY SSF55666 158 241 5.24E-24 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MC49_RS05520 f62134a6b0f3f1310212525da9892ec3 242 Pfam PF01138 3' exoribonuclease family, domain 1 14 144 2.0E-24 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MC49_RS05520 f62134a6b0f3f1310212525da9892ec3 242 ProSitePatterns PS01277 Ribonuclease PH signature. 120 133 - T 29-03-2018 IPR018336 Ribonuclease PH, conserved site MC49_RS15625 2a3ba197bb812c332f273f3310f4a68b 330 Pfam PF00005 ABC transporter 24 187 2.4E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS15625 2a3ba197bb812c332f273f3310f4a68b 330 SUPERFAMILY SSF52540 3 266 6.27E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS15625 2a3ba197bb812c332f273f3310f4a68b 330 Gene3D G3DSA:3.40.50.300 1 328 5.2E-58 T 29-03-2018 MC49_RS15625 2a3ba197bb812c332f273f3310f4a68b 330 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 238 305 1.1E-15 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MC49_RS15625 2a3ba197bb812c332f273f3310f4a68b 330 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 237 323 5.7E-19 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MC49_RS15625 2a3ba197bb812c332f273f3310f4a68b 330 SMART SM00382 32 232 2.0E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS11490 6e07d536de245e8f2119e7e9f4ded84f 74 Gene3D G3DSA:3.40.30.10 2 43 4.6E-4 T 29-03-2018 MC49_RS11490 6e07d536de245e8f2119e7e9f4ded84f 74 SUPERFAMILY SSF52833 2 39 4.76E-5 T 29-03-2018 IPR012336 Thioredoxin-like fold MC49_RS03850 99118239fdfafd959551e06763eb095d 431 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 163 171 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site MC49_RS03850 99118239fdfafd959551e06763eb095d 431 Gene3D G3DSA:3.40.50.300 232 430 1.9E-44 T 29-03-2018 MC49_RS03850 99118239fdfafd959551e06763eb095d 431 Hamap MF_00661 ATP-dependent RNA helicase RhlB [rhlB]. 8 389 50.596 T 29-03-2018 IPR023554 ATP-dependent RNA helicase RhlB type GO:0004004 MC49_RS03850 99118239fdfafd959551e06763eb095d 431 SMART SM00490 270 351 2.0E-30 T 29-03-2018 IPR001650 Helicase, C-terminal MC49_RS03850 99118239fdfafd959551e06763eb095d 431 Pfam PF00270 DEAD/DEAH box helicase 33 206 9.5E-44 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MC49_RS03850 99118239fdfafd959551e06763eb095d 431 SUPERFAMILY SSF52540 84 363 4.77E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS03850 99118239fdfafd959551e06763eb095d 431 Gene3D G3DSA:3.40.50.300 3 231 4.2E-48 T 29-03-2018 MC49_RS03850 99118239fdfafd959551e06763eb095d 431 Pfam PF00271 Helicase conserved C-terminal domain 243 351 7.5E-29 T 29-03-2018 IPR001650 Helicase, C-terminal MC49_RS03850 99118239fdfafd959551e06763eb095d 431 SMART SM00487 28 234 2.2E-51 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MC49_RS06410 18b58c9d52cb460cdc03b8a94eb763ac 233 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 29-03-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS06410 18b58c9d52cb460cdc03b8a94eb763ac 233 Gene3D G3DSA:3.30.190.20 150 228 4.2E-22 T 29-03-2018 MC49_RS06410 18b58c9d52cb460cdc03b8a94eb763ac 233 Gene3D G3DSA:3.40.50.790 68 149 3.2E-35 T 29-03-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich MC49_RS06410 18b58c9d52cb460cdc03b8a94eb763ac 233 Pfam PF00687 Ribosomal protein L1p/L10e family 30 219 3.1E-51 T 29-03-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein MC49_RS06410 18b58c9d52cb460cdc03b8a94eb763ac 233 SUPERFAMILY SSF56808 6 225 3.53E-83 T 29-03-2018 IPR023674 Ribosomal protein L1-like MC49_RS06410 18b58c9d52cb460cdc03b8a94eb763ac 233 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 43.757 T 29-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 MC49_RS06410 18b58c9d52cb460cdc03b8a94eb763ac 233 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 227 3.1E-108 T 29-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 MC49_RS06410 18b58c9d52cb460cdc03b8a94eb763ac 233 PIRSF PIRSF002155 1 227 3.6E-79 T 29-03-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS16990 9cdab19ae2421f99436d3c4849e9756a 410 Pfam PF07687 Peptidase dimerisation domain 205 303 1.8E-11 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain MC49_RS16990 9cdab19ae2421f99436d3c4849e9756a 410 Hamap MF_00550 Peptidase T [pepT]. 1 404 55.385 T 29-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 MC49_RS16990 9cdab19ae2421f99436d3c4849e9756a 410 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 73 82 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 MC49_RS16990 9cdab19ae2421f99436d3c4849e9756a 410 SUPERFAMILY SSF55031 208 320 8.89E-41 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain MC49_RS16990 9cdab19ae2421f99436d3c4849e9756a 410 SUPERFAMILY SSF53187 322 402 4.53E-80 T 29-03-2018 MC49_RS16990 9cdab19ae2421f99436d3c4849e9756a 410 SUPERFAMILY SSF53187 1 209 4.53E-80 T 29-03-2018 MC49_RS16990 9cdab19ae2421f99436d3c4849e9756a 410 Gene3D G3DSA:3.40.630.10 1 410 2.5E-47 T 29-03-2018 MC49_RS16990 9cdab19ae2421f99436d3c4849e9756a 410 TIGRFAM TIGR01882 peptidase-T: peptidase T 2 404 2.9E-156 T 29-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 MC49_RS16990 9cdab19ae2421f99436d3c4849e9756a 410 PIRSF PIRSF037215 1 407 9.1E-181 T 29-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 MC49_RS16990 9cdab19ae2421f99436d3c4849e9756a 410 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 138 176 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 MC49_RS16990 9cdab19ae2421f99436d3c4849e9756a 410 Pfam PF01546 Peptidase family M20/M25/M40 139 401 4.6E-14 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 MC49_RS17535 bb99609a32927c60bc0ad46634656132 61 Pfam PF04606 Ogr/Delta-like zinc finger 3 49 4.2E-18 T 29-03-2018 IPR007684 Zinc finger, Ogr/Delta-type MC49_RS05365 1fd1b32f7e5b7057753111dd27949bf4 454 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 216 370 6.4E-23 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MC49_RS05365 1fd1b32f7e5b7057753111dd27949bf4 454 Gene3D G3DSA:1.20.120.430 282 454 4.5E-32 T 29-03-2018 MC49_RS05365 1fd1b32f7e5b7057753111dd27949bf4 454 Pfam PF12631 MnmE helical domain 123 451 1.0E-59 T 29-03-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 MC49_RS05365 1fd1b32f7e5b7057753111dd27949bf4 454 Pfam PF10396 GTP-binding protein TrmE N-terminus 6 120 1.3E-34 T 29-03-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 MC49_RS05365 1fd1b32f7e5b7057753111dd27949bf4 454 SUPERFAMILY SSF52540 187 372 3.45E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS05365 1fd1b32f7e5b7057753111dd27949bf4 454 SUPERFAMILY SSF52540 72 152 3.45E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS05365 1fd1b32f7e5b7057753111dd27949bf4 454 SUPERFAMILY SSF116878 379 454 9.81E-51 T 29-03-2018 MC49_RS05365 1fd1b32f7e5b7057753111dd27949bf4 454 SUPERFAMILY SSF116878 121 220 9.81E-51 T 29-03-2018 MC49_RS05365 1fd1b32f7e5b7057753111dd27949bf4 454 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 11 454 2.0E-98 T 29-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 MC49_RS05365 1fd1b32f7e5b7057753111dd27949bf4 454 Gene3D G3DSA:3.30.1360.120 1 121 3.6E-40 T 29-03-2018 MC49_RS05365 1fd1b32f7e5b7057753111dd27949bf4 454 Pfam PF01926 50S ribosome-binding GTPase 218 335 1.5E-24 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MC49_RS05365 1fd1b32f7e5b7057753111dd27949bf4 454 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 5 454 32.898 T 29-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 MC49_RS05365 1fd1b32f7e5b7057753111dd27949bf4 454 Gene3D G3DSA:1.20.120.430 122 281 2.8E-27 T 29-03-2018 MC49_RS18055 751922096d281f050d7592a121401e06 378 TIGRFAM TIGR00843 benE: benzoate transporter 2 372 9.6E-128 T 29-03-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 MC49_RS18055 751922096d281f050d7592a121401e06 378 Pfam PF03594 Benzoate membrane transport protein 2 371 1.7E-137 T 29-03-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 MC49_RS14295 ed2ff38009088fdd4d5941da6ab8dca5 360 SUPERFAMILY SSF53807 30 344 2.51E-49 T 29-03-2018 MC49_RS14295 ed2ff38009088fdd4d5941da6ab8dca5 360 Gene3D G3DSA:3.40.50.1980 18 151 5.2E-16 T 29-03-2018 MC49_RS14295 ed2ff38009088fdd4d5941da6ab8dca5 360 Gene3D G3DSA:3.40.50.1980 152 326 2.1E-30 T 29-03-2018 MC49_RS14295 ed2ff38009088fdd4d5941da6ab8dca5 360 Pfam PF01497 Periplasmic binding protein 98 284 1.3E-16 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 MC49_RS11150 1aaa31ce69acc2e1ebffb8f095758b14 327 Gene3D G3DSA:3.40.50.300 44 227 2.0E-7 T 29-03-2018 MC49_RS11150 1aaa31ce69acc2e1ebffb8f095758b14 327 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 13 318 6.7E-118 T 29-03-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 MC49_RS11150 1aaa31ce69acc2e1ebffb8f095758b14 327 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 19 325 5.9E-107 T 29-03-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 MC49_RS11150 1aaa31ce69acc2e1ebffb8f095758b14 327 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 1 325 42.068 T 29-03-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 MC49_RS11150 1aaa31ce69acc2e1ebffb8f095758b14 327 SUPERFAMILY SSF52540 46 161 8.99E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS17470 6757ed01868fbffeff54a863d4d9c405 122 Gene3D G3DSA:1.20.1260.10 11 117 2.7E-27 T 29-03-2018 IPR012347 Ferritin-related MC49_RS17470 6757ed01868fbffeff54a863d4d9c405 122 Pfam PF03713 Domain of unknown function (DUF305) 39 114 8.1E-22 T 29-03-2018 IPR005183 Domain of unknown function DUF305 MC49_RS02395 3b45fd092a1c337ce709ce1013b6f653 871 SUPERFAMILY SSF141729 41 162 2.09E-30 T 29-03-2018 MC49_RS02395 3b45fd092a1c337ce709ce1013b6f653 871 Pfam PF13954 PapC N-terminal domain 42 186 8.4E-38 T 29-03-2018 IPR025885 PapC, N-terminal domain GO:0005515 MC49_RS02395 3b45fd092a1c337ce709ce1013b6f653 871 Pfam PF00577 Outer membrane usher protein 205 753 1.8E-184 T 29-03-2018 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 MC49_RS02395 3b45fd092a1c337ce709ce1013b6f653 871 Pfam PF13953 PapC C-terminal domain 765 821 1.2E-13 T 29-03-2018 IPR025949 PapC-like, C-terminal domain MC49_RS09125 7a673a15a938409dde173d35f9c39171 449 Gene3D G3DSA:3.20.20.70 87 337 2.4E-26 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS09125 7a673a15a938409dde173d35f9c39171 449 SUPERFAMILY SSF102114 98 262 2.75E-19 T 29-03-2018 MC49_RS09125 7a673a15a938409dde173d35f9c39171 449 Pfam PF04055 Radical SAM superfamily 100 248 1.3E-15 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MC49_RS09125 7a673a15a938409dde173d35f9c39171 449 Pfam PF13353 4Fe-4S single cluster domain 89 173 1.4E-6 T 29-03-2018 MC49_RS09125 7a673a15a938409dde173d35f9c39171 449 SMART SM00729 94 293 0.0016 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MC49_RS05965 827c77c492357aab18b2d385057ce20e 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.0E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS05965 827c77c492357aab18b2d385057ce20e 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.0E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS05965 827c77c492357aab18b2d385057ce20e 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.0E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS05965 827c77c492357aab18b2d385057ce20e 303 Gene3D G3DSA:3.40.190.10 87 175 6.6E-21 T 29-03-2018 MC49_RS05965 827c77c492357aab18b2d385057ce20e 303 Pfam PF03466 LysR substrate binding domain 88 292 3.4E-51 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS05965 827c77c492357aab18b2d385057ce20e 303 Gene3D G3DSA:1.10.10.10 1 82 8.5E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS05965 827c77c492357aab18b2d385057ce20e 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.3E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS05965 827c77c492357aab18b2d385057ce20e 303 Gene3D G3DSA:3.40.190.10 176 264 3.7E-26 T 29-03-2018 MC49_RS05965 827c77c492357aab18b2d385057ce20e 303 SUPERFAMILY SSF53850 89 293 4.65E-44 T 29-03-2018 MC49_RS05965 827c77c492357aab18b2d385057ce20e 303 SUPERFAMILY SSF46785 1 111 2.56E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS02205 6b5353a20023f94e649f55e3988b951d 735 SUPERFAMILY SSF69255 362 449 2.38E-29 T 29-03-2018 MC49_RS02205 6b5353a20023f94e649f55e3988b951d 735 SUPERFAMILY SSF69279 191 363 2.38E-32 T 29-03-2018 MC49_RS02205 6b5353a20023f94e649f55e3988b951d 735 Pfam PF05954 Phage late control gene D protein (GPD) 37 329 2.7E-68 T 29-03-2018 MC49_RS02205 6b5353a20023f94e649f55e3988b951d 735 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 29 501 5.9E-106 T 29-03-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein MC49_RS02205 6b5353a20023f94e649f55e3988b951d 735 SUPERFAMILY SSF69349 440 632 1.1E-42 T 29-03-2018 MC49_RS02205 6b5353a20023f94e649f55e3988b951d 735 Gene3D G3DSA:3.55.50.10 106 209 3.9E-19 T 29-03-2018 MC49_RS02205 6b5353a20023f94e649f55e3988b951d 735 Gene3D G3DSA:2.40.50.230 368 450 6.5E-32 T 29-03-2018 IPR006531 Gp5 N-terminal MC49_RS02205 6b5353a20023f94e649f55e3988b951d 735 SUPERFAMILY SSF69279 22 191 2.89E-41 T 29-03-2018 MC49_RS02205 6b5353a20023f94e649f55e3988b951d 735 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 17 518 1.9E-165 T 29-03-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset MC49_RS10345 e0036d65102a745d7379eae1f0476e03 270 Gene3D G3DSA:1.10.10.60 226 270 9.0E-8 T 29-03-2018 MC49_RS10345 e0036d65102a745d7379eae1f0476e03 270 Pfam PF12833 Helix-turn-helix domain 192 268 3.7E-18 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MC49_RS10345 e0036d65102a745d7379eae1f0476e03 270 Gene3D G3DSA:2.60.120.10 8 104 1.8E-4 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MC49_RS10345 e0036d65102a745d7379eae1f0476e03 270 SUPERFAMILY SSF46689 222 268 8.96E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS10345 e0036d65102a745d7379eae1f0476e03 270 Gene3D G3DSA:1.10.10.60 174 225 2.7E-9 T 29-03-2018 MC49_RS10345 e0036d65102a745d7379eae1f0476e03 270 SUPERFAMILY SSF51182 27 228 8.89E-10 T 29-03-2018 IPR011051 RmlC-like cupin domain MC49_RS10345 e0036d65102a745d7379eae1f0476e03 270 SMART SM00342 186 268 9.5E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MC49_RS16920 4b2b046c4e907dee6909754ed061d723 219 SUPERFAMILY SSF50494 4 204 2.43E-13 T 29-03-2018 IPR009003 Peptidase S1, PA clan MC49_RS04935 76515d82cf5969757671efeb1ba0f1ad 582 Gene3D G3DSA:1.10.287.1120 261 369 4.4E-13 T 29-03-2018 MC49_RS04935 76515d82cf5969757671efeb1ba0f1ad 582 SUPERFAMILY SSF116734 370 568 1.96E-35 T 29-03-2018 MC49_RS04935 76515d82cf5969757671efeb1ba0f1ad 582 Pfam PF01420 Type I restriction modification DNA specificity domain 386 561 5.0E-14 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 MC49_RS04935 76515d82cf5969757671efeb1ba0f1ad 582 Pfam PF01420 Type I restriction modification DNA specificity domain 102 276 2.1E-17 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 MC49_RS04935 76515d82cf5969757671efeb1ba0f1ad 582 Gene3D G3DSA:3.90.220.20 370 541 4.5E-26 T 29-03-2018 MC49_RS04935 76515d82cf5969757671efeb1ba0f1ad 582 SUPERFAMILY SSF116734 98 276 5.23E-45 T 29-03-2018 MC49_RS04935 76515d82cf5969757671efeb1ba0f1ad 582 SUPERFAMILY SSF116734 322 346 5.23E-45 T 29-03-2018 MC49_RS04935 76515d82cf5969757671efeb1ba0f1ad 582 Gene3D G3DSA:3.90.220.20 38 260 1.5E-37 T 29-03-2018 MC49_RS18315 4f74514a9f34f3a52ceaad8c04b9a223 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 8.7E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS18315 4f74514a9f34f3a52ceaad8c04b9a223 312 SUPERFAMILY SSF46785 1 86 6.29E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS18315 4f74514a9f34f3a52ceaad8c04b9a223 312 Gene3D G3DSA:1.10.10.10 1 85 3.1E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS18315 4f74514a9f34f3a52ceaad8c04b9a223 312 SUPERFAMILY SSF53850 88 294 2.53E-50 T 29-03-2018 MC49_RS18315 4f74514a9f34f3a52ceaad8c04b9a223 312 Pfam PF03466 LysR substrate binding domain 87 291 1.5E-48 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS18315 4f74514a9f34f3a52ceaad8c04b9a223 312 Gene3D G3DSA:3.40.190.10 176 262 2.7E-29 T 29-03-2018 MC49_RS18315 4f74514a9f34f3a52ceaad8c04b9a223 312 Gene3D G3DSA:3.40.190.10 86 175 2.4E-18 T 29-03-2018 MC49_RS18315 4f74514a9f34f3a52ceaad8c04b9a223 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.1E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS18315 4f74514a9f34f3a52ceaad8c04b9a223 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.1E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS18315 4f74514a9f34f3a52ceaad8c04b9a223 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.1E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS12455 7c288545304b04fe0c15a8472c0ab4ec 287 Pfam PF03705 CheR methyltransferase, all-alpha domain 13 65 1.4E-15 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal MC49_RS12455 7c288545304b04fe0c15a8472c0ab4ec 287 SMART SM00138 12 273 1.1E-98 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MC49_RS12455 7c288545304b04fe0c15a8472c0ab4ec 287 PIRSF PIRSF000410 3 274 6.7E-97 T 29-03-2018 IPR026024 Chemotaxis protein methyltransferase CheR MC49_RS12455 7c288545304b04fe0c15a8472c0ab4ec 287 PRINTS PR00996 Glutamate methyltransferase family signature 213 227 1.2E-47 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MC49_RS12455 7c288545304b04fe0c15a8472c0ab4ec 287 PRINTS PR00996 Glutamate methyltransferase family signature 232 255 1.2E-47 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MC49_RS12455 7c288545304b04fe0c15a8472c0ab4ec 287 PRINTS PR00996 Glutamate methyltransferase family signature 34 47 1.2E-47 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MC49_RS12455 7c288545304b04fe0c15a8472c0ab4ec 287 PRINTS PR00996 Glutamate methyltransferase family signature 73 85 1.2E-47 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MC49_RS12455 7c288545304b04fe0c15a8472c0ab4ec 287 PRINTS PR00996 Glutamate methyltransferase family signature 141 157 1.2E-47 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MC49_RS12455 7c288545304b04fe0c15a8472c0ab4ec 287 PRINTS PR00996 Glutamate methyltransferase family signature 107 127 1.2E-47 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MC49_RS12455 7c288545304b04fe0c15a8472c0ab4ec 287 SUPERFAMILY SSF53335 80 270 1.06E-57 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS12455 7c288545304b04fe0c15a8472c0ab4ec 287 Gene3D G3DSA:3.40.50.150 79 273 3.8E-49 T 29-03-2018 MC49_RS12455 7c288545304b04fe0c15a8472c0ab4ec 287 Gene3D G3DSA:1.10.155.10 6 78 1.6E-22 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal MC49_RS12455 7c288545304b04fe0c15a8472c0ab4ec 287 SUPERFAMILY SSF47757 6 79 1.57E-20 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal MC49_RS12455 7c288545304b04fe0c15a8472c0ab4ec 287 Pfam PF01739 CheR methyltransferase, SAM binding domain 80 265 2.4E-60 T 29-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal MC49_RS03830 beb1fc65df14704c89e669d036989c79 351 Gene3D G3DSA:3.30.1890.10 43 206 2.1E-52 T 29-03-2018 MC49_RS03830 beb1fc65df14704c89e669d036989c79 351 SUPERFAMILY SSF160355 55 322 1.03E-76 T 29-03-2018 MC49_RS03830 beb1fc65df14704c89e669d036989c79 351 Pfam PF02706 Chain length determinant protein 17 83 8.6E-11 T 29-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 MC49_RS03830 beb1fc65df14704c89e669d036989c79 351 Hamap MF_02025 ECA polysaccharide chain length modulation protein [wzzE]. 9 351 55.135 T 29-03-2018 IPR032895 ECA polysaccharide chain length modulation protein WzzE GO:0009246|GO:0016021 MC49_RS03830 beb1fc65df14704c89e669d036989c79 351 Gene3D G3DSA:1.10.287.210 207 298 1.6E-16 T 29-03-2018 MC49_RS18960 ddba10bbd7c31d2453fc427d8dd2eb03 72 SUPERFAMILY SSF47413 6 70 1.72E-20 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS18960 ddba10bbd7c31d2453fc427d8dd2eb03 72 Gene3D G3DSA:1.10.260.40 1 72 7.7E-19 T 29-03-2018 MC49_RS18960 ddba10bbd7c31d2453fc427d8dd2eb03 72 Pfam PF01381 Helix-turn-helix 14 68 3.8E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS18960 ddba10bbd7c31d2453fc427d8dd2eb03 72 SMART SM00530 13 68 2.9E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS11175 ce0b00f782ca236bf4130deacfb8f9ff 262 Gene3D G3DSA:3.40.50.150 8 261 1.8E-48 T 29-03-2018 MC49_RS11175 ce0b00f782ca236bf4130deacfb8f9ff 262 Pfam PF13649 Methyltransferase domain 48 143 1.3E-14 T 29-03-2018 MC49_RS11175 ce0b00f782ca236bf4130deacfb8f9ff 262 Hamap MF_02057 tRNA 5-carboxymethoxyuridine methyltransferase [cmoM]. 2 255 40.988 T 29-03-2018 IPR033664 tRNA 5-carboxymethoxyuridine methyltransferase GO:0008168 MC49_RS11175 ce0b00f782ca236bf4130deacfb8f9ff 262 SUPERFAMILY SSF53335 3 255 4.56E-38 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS08710 3375a6abba7fa30fa70b132f7e94eb42 271 SUPERFAMILY SSF53623 30 79 8.79E-7 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MC49_RS08710 3375a6abba7fa30fa70b132f7e94eb42 271 Gene3D G3DSA:3.40.1190.10 22 144 1.4E-7 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MC49_RS08710 3375a6abba7fa30fa70b132f7e94eb42 271 TIGRFAM TIGR03172 TIGR03172: putative selenium-dependent hydroxylase accessory protein YqeC 37 261 5.1E-66 T 29-03-2018 IPR017587 Putative selenium-dependent hydroxylase accessory protein YqeC MC49_RS16335 d2172d2b435db700005a9db8780b74ec 297 Gene3D G3DSA:3.40.50.10330 2 131 3.2E-26 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 MC49_RS16335 d2172d2b435db700005a9db8780b74ec 297 Hamap MF_01377 Probable lipid kinase YegS [yegS]. 4 297 43.137 T 29-03-2018 IPR022433 Lipid kinase YegS GO:0001727|GO:0046872 MC49_RS16335 d2172d2b435db700005a9db8780b74ec 297 Pfam PF00781 Diacylglycerol kinase catalytic domain 7 126 8.9E-27 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 MC49_RS16335 d2172d2b435db700005a9db8780b74ec 297 SUPERFAMILY SSF111331 5 293 6.98E-71 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain MC49_RS16335 d2172d2b435db700005a9db8780b74ec 297 SMART SM00046 4 130 5.3E-14 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 MC49_RS16335 d2172d2b435db700005a9db8780b74ec 297 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 6 291 7.6E-82 T 29-03-2018 IPR005218 Diacylglycerol/lipid kinase MC49_RS17970 2065341d0d25acd35c1508476ac28c3e 471 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 3 306 2.9E-120 T 29-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 MC49_RS17970 2065341d0d25acd35c1508476ac28c3e 471 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 3 463 5.9E-203 T 29-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 MC49_RS17970 2065341d0d25acd35c1508476ac28c3e 471 Gene3D G3DSA:1.10.10.350 367 471 3.6E-23 T 29-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 MC49_RS17970 2065341d0d25acd35c1508476ac28c3e 471 PRINTS PR00987 Glutamyl-tRNA synthetase signature 7 19 3.9E-27 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 MC49_RS17970 2065341d0d25acd35c1508476ac28c3e 471 PRINTS PR00987 Glutamyl-tRNA synthetase signature 36 49 3.9E-27 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 MC49_RS17970 2065341d0d25acd35c1508476ac28c3e 471 PRINTS PR00987 Glutamyl-tRNA synthetase signature 180 190 3.9E-27 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 MC49_RS17970 2065341d0d25acd35c1508476ac28c3e 471 PRINTS PR00987 Glutamyl-tRNA synthetase signature 196 204 3.9E-27 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 MC49_RS17970 2065341d0d25acd35c1508476ac28c3e 471 PRINTS PR00987 Glutamyl-tRNA synthetase signature 21 32 3.9E-27 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 MC49_RS17970 2065341d0d25acd35c1508476ac28c3e 471 Gene3D G3DSA:1.10.8.70 318 361 4.0E-12 T 29-03-2018 IPR020752 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 MC49_RS17970 2065341d0d25acd35c1508476ac28c3e 471 Gene3D G3DSA:3.40.50.620 4 119 1.8E-41 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS17970 2065341d0d25acd35c1508476ac28c3e 471 SUPERFAMILY SSF48163 300 462 2.09E-45 T 29-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 MC49_RS17970 2065341d0d25acd35c1508476ac28c3e 471 SUPERFAMILY SSF52374 3 299 5.9E-112 T 29-03-2018 MC49_RS17970 2065341d0d25acd35c1508476ac28c3e 471 Gene3D G3DSA:3.40.50.620 120 231 4.6E-28 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS17970 2065341d0d25acd35c1508476ac28c3e 471 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 21 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS17970 2065341d0d25acd35c1508476ac28c3e 471 Gene3D G3DSA:1.10.1160.10 233 315 5.6E-34 T 29-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 MC49_RS17970 2065341d0d25acd35c1508476ac28c3e 471 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 3 462 32.532 T 29-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 MC49_RS18485 701aa47e1453c12abb8e5696b639c5c0 416 Gene3D G3DSA:3.40.50.720 2 136 2.5E-44 T 29-03-2018 MC49_RS18485 701aa47e1453c12abb8e5696b639c5c0 416 Gene3D G3DSA:3.40.50.720 137 298 3.2E-40 T 29-03-2018 MC49_RS18485 701aa47e1453c12abb8e5696b639c5c0 416 SUPERFAMILY SSF55021 341 415 4.93E-17 T 29-03-2018 MC49_RS18485 701aa47e1453c12abb8e5696b639c5c0 416 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 200 222 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site MC49_RS18485 701aa47e1453c12abb8e5696b639c5c0 416 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 154 181 - T 29-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 MC49_RS18485 701aa47e1453c12abb8e5696b639c5c0 416 SUPERFAMILY SSF51735 108 298 1.29E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS18485 701aa47e1453c12abb8e5696b639c5c0 416 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 118 297 1.0E-51 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MC49_RS18485 701aa47e1453c12abb8e5696b639c5c0 416 Gene3D G3DSA:3.30.70.260 331 415 2.9E-14 T 29-03-2018 MC49_RS18485 701aa47e1453c12abb8e5696b639c5c0 416 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 14 329 4.1E-37 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 MC49_RS18485 701aa47e1453c12abb8e5696b639c5c0 416 SUPERFAMILY SSF52283 7 137 1.51E-50 T 29-03-2018 MC49_RS18485 701aa47e1453c12abb8e5696b639c5c0 416 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 229 245 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site MC49_RS11335 b88fbde644c66f2b01b1aafbf5def082 152 PIRSF PIRSF006614 8 151 4.6E-65 T 29-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 MC49_RS11335 b88fbde644c66f2b01b1aafbf5def082 152 Hamap MF_00549 Methylglyoxal synthase [mgsA]. 12 131 36.681 T 29-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 MC49_RS11335 b88fbde644c66f2b01b1aafbf5def082 152 SMART SM00851 25 118 9.1E-27 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain MC49_RS11335 b88fbde644c66f2b01b1aafbf5def082 152 Gene3D G3DSA:3.40.50.1380 1 152 2.2E-44 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain MC49_RS11335 b88fbde644c66f2b01b1aafbf5def082 152 Pfam PF02142 MGS-like domain 26 118 2.9E-20 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain MC49_RS11335 b88fbde644c66f2b01b1aafbf5def082 152 ProSitePatterns PS01335 Methylglyoxal synthase active site. 65 73 - T 29-03-2018 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 MC49_RS11335 b88fbde644c66f2b01b1aafbf5def082 152 TIGRFAM TIGR00160 MGSA: methylglyoxal synthase 11 151 1.3E-66 T 29-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 MC49_RS11335 b88fbde644c66f2b01b1aafbf5def082 152 SUPERFAMILY SSF52335 5 150 2.75E-59 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain MC49_RS12210 ecbf94eb19f0592d14857553ceee0968 501 Gene3D G3DSA:3.30.300.20 397 470 7.1E-26 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta MC49_RS12210 ecbf94eb19f0592d14857553ceee0968 501 Gene3D G3DSA:1.20.120.430 2 67 6.1E-16 T 29-03-2018 MC49_RS12210 ecbf94eb19f0592d14857553ceee0968 501 PIRSF PIRSF006485 1 477 1.3E-180 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 MC49_RS12210 ecbf94eb19f0592d14857553ceee0968 501 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 3 469 1.1E-176 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 MC49_RS12210 ecbf94eb19f0592d14857553ceee0968 501 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 389 469 9.8E-25 T 29-03-2018 IPR032859 GTPase Der, C-terminal KH-domain-like MC49_RS12210 ecbf94eb19f0592d14857553ceee0968 501 Pfam PF01926 50S ribosome-binding GTPase 5 120 1.6E-26 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MC49_RS12210 ecbf94eb19f0592d14857553ceee0968 501 Pfam PF01926 50S ribosome-binding GTPase 216 333 2.8E-24 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MC49_RS12210 ecbf94eb19f0592d14857553ceee0968 501 Gene3D G3DSA:1.20.120.430 283 396 1.7E-16 T 29-03-2018 MC49_RS12210 ecbf94eb19f0592d14857553ceee0968 501 Gene3D G3DSA:1.20.120.430 68 282 1.9E-46 T 29-03-2018 MC49_RS12210 ecbf94eb19f0592d14857553ceee0968 501 SUPERFAMILY SSF52540 211 476 3.07E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS12210 ecbf94eb19f0592d14857553ceee0968 501 SUPERFAMILY SSF52540 139 168 3.07E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS12210 ecbf94eb19f0592d14857553ceee0968 501 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 156 2.6E-22 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MC49_RS12210 ecbf94eb19f0592d14857553ceee0968 501 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 212 379 3.5E-23 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MC49_RS12210 ecbf94eb19f0592d14857553ceee0968 501 Hamap MF_00195 GTPase Der [der]. 2 472 38.898 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 MC49_RS12210 ecbf94eb19f0592d14857553ceee0968 501 SUPERFAMILY SSF52540 4 164 4.43E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS12210 ecbf94eb19f0592d14857553ceee0968 501 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 1.9E-9 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MC49_RS12210 ecbf94eb19f0592d14857553ceee0968 501 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 72 90 1.9E-9 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MC49_RS02100 81d5995b761cf57c95a3d9b1b82cc650 119 Pfam PF13698 Domain of unknown function (DUF4156) 26 118 2.8E-30 T 29-03-2018 IPR025294 Protein of unknown function DUF4156 MC49_RS07385 3c6d70769ef25af49056cfb3254405aa 265 SMART SM00382 35 222 8.0E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS07385 3c6d70769ef25af49056cfb3254405aa 265 SUPERFAMILY SSF52540 23 236 5.81E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS07385 3c6d70769ef25af49056cfb3254405aa 265 Gene3D G3DSA:3.40.50.300 1 259 1.7E-42 T 29-03-2018 MC49_RS07385 3c6d70769ef25af49056cfb3254405aa 265 Pfam PF00005 ABC transporter 26 175 2.7E-17 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS08900 96b8f66aac059550d7d0a61e537f7ab1 414 ProSitePatterns PS00594 Aromatic amino acids permeases signature. 25 41 - T 29-03-2018 IPR013061 Tryptophan/tryrosine permease, conserved site MC49_RS08900 96b8f66aac059550d7d0a61e537f7ab1 414 PRINTS PR00166 Aromatic amino acid permease signature 18 41 3.4E-103 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS08900 96b8f66aac059550d7d0a61e537f7ab1 414 PRINTS PR00166 Aromatic amino acid permease signature 90 110 3.4E-103 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS08900 96b8f66aac059550d7d0a61e537f7ab1 414 PRINTS PR00166 Aromatic amino acid permease signature 232 251 3.4E-103 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS08900 96b8f66aac059550d7d0a61e537f7ab1 414 PRINTS PR00166 Aromatic amino acid permease signature 193 215 3.4E-103 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS08900 96b8f66aac059550d7d0a61e537f7ab1 414 PRINTS PR00166 Aromatic amino acid permease signature 45 64 3.4E-103 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS08900 96b8f66aac059550d7d0a61e537f7ab1 414 PRINTS PR00166 Aromatic amino acid permease signature 293 312 3.4E-103 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS08900 96b8f66aac059550d7d0a61e537f7ab1 414 PRINTS PR00166 Aromatic amino acid permease signature 155 175 3.4E-103 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS08900 96b8f66aac059550d7d0a61e537f7ab1 414 PRINTS PR00166 Aromatic amino acid permease signature 327 345 3.4E-103 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS08900 96b8f66aac059550d7d0a61e537f7ab1 414 PRINTS PR00166 Aromatic amino acid permease signature 348 367 3.4E-103 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS08900 96b8f66aac059550d7d0a61e537f7ab1 414 TIGRFAM TIGR00837 araaP: aromatic amino acid transport protein 15 395 4.1E-157 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS08900 96b8f66aac059550d7d0a61e537f7ab1 414 Pfam PF03222 Tryptophan/tyrosine permease family 10 402 2.5E-151 T 29-03-2018 IPR018227 Amino acid/polyamine transporter 2 GO:0003333 MC49_RS01460 033c55918a6d8eba648d735c24bdd2fb 142 Gene3D G3DSA:3.90.1180.10 1 142 3.4E-63 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 MC49_RS01460 033c55918a6d8eba648d735c24bdd2fb 142 Pfam PF00572 Ribosomal protein L13 15 138 3.5E-57 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 MC49_RS01460 033c55918a6d8eba648d735c24bdd2fb 142 PIRSF PIRSF002181 1 142 2.1E-51 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 MC49_RS01460 033c55918a6d8eba648d735c24bdd2fb 142 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 4 142 2.5E-67 T 29-03-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS01460 033c55918a6d8eba648d735c24bdd2fb 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 141 28.323 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 MC49_RS01460 033c55918a6d8eba648d735c24bdd2fb 142 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 29-03-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 MC49_RS01460 033c55918a6d8eba648d735c24bdd2fb 142 SUPERFAMILY SSF52161 1 140 2.49E-60 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 MC49_RS05070 4228bf62f1be3291727b0bbfe3e7b6c9 330 Pfam PF13377 Periplasmic binding protein-like domain 166 327 4.3E-42 T 29-03-2018 MC49_RS05070 4228bf62f1be3291727b0bbfe3e7b6c9 330 ProSitePatterns PS00356 LacI-type HTH domain signature. 1 19 - T 29-03-2018 MC49_RS05070 4228bf62f1be3291727b0bbfe3e7b6c9 330 Gene3D G3DSA:1.10.260.40 1 51 2.6E-21 T 29-03-2018 MC49_RS05070 4228bf62f1be3291727b0bbfe3e7b6c9 330 SUPERFAMILY SSF53822 58 328 1.81E-90 T 29-03-2018 IPR028082 Periplasmic binding protein-like I MC49_RS05070 4228bf62f1be3291727b0bbfe3e7b6c9 330 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 45 8.3E-20 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MC49_RS05070 4228bf62f1be3291727b0bbfe3e7b6c9 330 Gene3D G3DSA:3.40.50.2300 173 304 1.5E-46 T 29-03-2018 MC49_RS05070 4228bf62f1be3291727b0bbfe3e7b6c9 330 SUPERFAMILY SSF47413 1 57 5.04E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS05070 4228bf62f1be3291727b0bbfe3e7b6c9 330 Gene3D G3DSA:3.40.50.2300 52 172 1.7E-30 T 29-03-2018 MC49_RS05070 4228bf62f1be3291727b0bbfe3e7b6c9 330 SMART SM00354 1 68 8.5E-31 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MC49_RS04570 40e96e060aa339959bd272902d121692 326 Gene3D G3DSA:3.40.190.10 145 221 3.5E-7 T 29-03-2018 MC49_RS04570 40e96e060aa339959bd272902d121692 326 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 31 310 8.2E-88 T 29-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 MC49_RS04570 40e96e060aa339959bd272902d121692 326 SUPERFAMILY SSF53850 138 272 2.43E-7 T 29-03-2018 MC49_RS04570 40e96e060aa339959bd272902d121692 326 PIRSF PIRSF006470 3 323 2.4E-96 T 29-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 MC49_RS04570 40e96e060aa339959bd272902d121692 326 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 31 285 2.7E-80 T 29-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 MC49_RS12590 cd53679c3d255157885f3716db286279 246 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 174 189 - T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MC49_RS12590 cd53679c3d255157885f3716db286279 246 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 105 117 6.5E-32 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 MC49_RS12590 cd53679c3d255157885f3716db286279 246 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 235 245 6.5E-32 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 MC49_RS12590 cd53679c3d255157885f3716db286279 246 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 45 54 6.5E-32 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 MC49_RS12590 cd53679c3d255157885f3716db286279 246 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 117 131 6.5E-32 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 MC49_RS12590 cd53679c3d255157885f3716db286279 246 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 167 179 6.5E-32 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 MC49_RS12590 cd53679c3d255157885f3716db286279 246 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 145 157 6.5E-32 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 MC49_RS12590 cd53679c3d255157885f3716db286279 246 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 222 234 - T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MC49_RS12590 cd53679c3d255157885f3716db286279 246 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 47 66 6.2E-68 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MC49_RS12590 cd53679c3d255157885f3716db286279 246 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 66 86 6.2E-68 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MC49_RS12590 cd53679c3d255157885f3716db286279 246 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 86 105 6.2E-68 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MC49_RS12590 cd53679c3d255157885f3716db286279 246 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 174 194 6.2E-68 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MC49_RS12590 cd53679c3d255157885f3716db286279 246 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 219 244 6.2E-68 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MC49_RS12590 cd53679c3d255157885f3716db286279 246 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 195 216 6.2E-68 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MC49_RS12590 cd53679c3d255157885f3716db286279 246 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 49 245 4.7E-93 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 MC49_RS12590 cd53679c3d255157885f3716db286279 246 Pfam PF00813 FliP family 50 241 1.1E-80 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MC49_RS18705 7c6b1ac220e09d10ad9de57c8c303d1b 173 Gene3D G3DSA:3.30.70.1150 98 171 3.8E-25 T 29-03-2018 MC49_RS18705 7c6b1ac220e09d10ad9de57c8c303d1b 173 SUPERFAMILY SSF55021 12 85 5.89E-21 T 29-03-2018 MC49_RS18705 7c6b1ac220e09d10ad9de57c8c303d1b 173 Pfam PF10369 Small subunit of acetolactate synthase 94 168 2.9E-24 T 29-03-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 MC49_RS18705 7c6b1ac220e09d10ad9de57c8c303d1b 173 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 11 169 1.6E-64 T 29-03-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 MC49_RS18705 7c6b1ac220e09d10ad9de57c8c303d1b 173 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 11 86 2.0E-32 T 29-03-2018 MC49_RS18705 7c6b1ac220e09d10ad9de57c8c303d1b 173 SUPERFAMILY SSF55021 90 172 9.61E-26 T 29-03-2018 MC49_RS18705 7c6b1ac220e09d10ad9de57c8c303d1b 173 Pfam PF13710 ACT domain 23 83 1.1E-15 T 29-03-2018 MC49_RS18705 7c6b1ac220e09d10ad9de57c8c303d1b 173 Gene3D G3DSA:3.30.70.260 11 97 4.4E-23 T 29-03-2018 MC49_RS15890 593a96ae9542b27b14b5faab536f4049 175 Gene3D G3DSA:2.60.40.200 20 173 3.1E-40 T 29-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 MC49_RS15890 593a96ae9542b27b14b5faab536f4049 175 SUPERFAMILY SSF49329 24 172 2.75E-49 T 29-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 MC49_RS15890 593a96ae9542b27b14b5faab536f4049 175 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 33 172 1.8E-33 T 29-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 MC49_RS15890 593a96ae9542b27b14b5faab536f4049 175 ProSitePatterns PS00087 Copper/Zinc superoxide dismutase signature 1. 65 75 - T 29-03-2018 IPR018152 Superoxide dismutase, copper/zinc, binding site GO:0004784|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 MC49_RS15890 593a96ae9542b27b14b5faab536f4049 175 ProSitePatterns PS00332 Copper/Zinc superoxide dismutase signature 2. 161 172 - T 29-03-2018 IPR018152 Superoxide dismutase, copper/zinc, binding site GO:0004784|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 MC49_RS05355 7ec7ea7aca9f6191e7fbb976451d4c00 85 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 22 75 3.0E-24 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor MC49_RS05355 7ec7ea7aca9f6191e7fbb976451d4c00 85 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 12 83 2.0E-33 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor MC49_RS05355 7ec7ea7aca9f6191e7fbb976451d4c00 85 SMART SM01234 8 75 1.3E-44 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor MC49_RS05355 7ec7ea7aca9f6191e7fbb976451d4c00 85 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 8 76 24.533 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor MC49_RS05355 7ec7ea7aca9f6191e7fbb976451d4c00 85 Pfam PF01809 Haemolytic domain 10 75 8.0E-30 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor MC49_RS11055 8621d6fc93838983f1373cbec1844487 589 SUPERFAMILY SSF90123 11 338 7.46E-54 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MC49_RS11055 8621d6fc93838983f1373cbec1844487 589 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 20 557 2.8E-191 T 29-03-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 MC49_RS11055 8621d6fc93838983f1373cbec1844487 589 Gene3D G3DSA:1.20.1560.10 4 340 3.7E-43 T 29-03-2018 MC49_RS11055 8621d6fc93838983f1373cbec1844487 589 ProSitePatterns PS00211 ABC transporters family signature. 487 501 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS11055 8621d6fc93838983f1373cbec1844487 589 Pfam PF00005 ABC transporter 370 515 2.3E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS11055 8621d6fc93838983f1373cbec1844487 589 SMART SM00382 376 561 9.5E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS11055 8621d6fc93838983f1373cbec1844487 589 SUPERFAMILY SSF52540 363 583 3.03E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS11055 8621d6fc93838983f1373cbec1844487 589 Gene3D G3DSA:3.40.50.300 341 588 2.4E-61 T 29-03-2018 MC49_RS11055 8621d6fc93838983f1373cbec1844487 589 Pfam PF00664 ABC transporter transmembrane region 26 292 2.9E-38 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MC49_RS08800 8aca6d20ceb0ced793df883cc420cfe1 123 Gene3D G3DSA:1.10.10.10 23 121 8.3E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS08800 8aca6d20ceb0ced793df883cc420cfe1 123 Pfam PF01638 HxlR-like helix-turn-helix 26 111 1.8E-31 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type MC49_RS08800 8aca6d20ceb0ced793df883cc420cfe1 123 SUPERFAMILY SSF46785 14 113 1.25E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS14760 807941ba85606ee2f3b5b2cc3d7df2d7 324 Gene3D G3DSA:3.40.50.1820 6 320 1.8E-65 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS14760 807941ba85606ee2f3b5b2cc3d7df2d7 324 Pfam PF00561 alpha/beta hydrolase fold 46 303 5.4E-26 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MC49_RS14760 807941ba85606ee2f3b5b2cc3d7df2d7 324 PIRSF PIRSF006431 7 322 8.4E-133 T 29-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 MC49_RS14760 807941ba85606ee2f3b5b2cc3d7df2d7 324 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 45 53 5.2E-13 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MC49_RS14760 807941ba85606ee2f3b5b2cc3d7df2d7 324 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 71 82 5.2E-13 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MC49_RS14760 807941ba85606ee2f3b5b2cc3d7df2d7 324 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 114 128 5.2E-13 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MC49_RS14760 807941ba85606ee2f3b5b2cc3d7df2d7 324 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 17 318 3.1E-118 T 29-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 MC49_RS14760 807941ba85606ee2f3b5b2cc3d7df2d7 324 SUPERFAMILY SSF53474 6 304 2.04E-61 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS15250 8a3b63c11ebd45e4848afef2c8a1508f 486 Gene3D G3DSA:3.30.870.10 316 474 2.8E-26 T 29-03-2018 MC49_RS15250 8a3b63c11ebd45e4848afef2c8a1508f 486 Gene3D G3DSA:3.30.870.10 118 297 1.8E-27 T 29-03-2018 MC49_RS15250 8a3b63c11ebd45e4848afef2c8a1508f 486 SMART SM00155 399 426 1.7E-5 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MC49_RS15250 8a3b63c11ebd45e4848afef2c8a1508f 486 SMART SM00155 219 246 0.0034 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MC49_RS15250 8a3b63c11ebd45e4848afef2c8a1508f 486 SUPERFAMILY SSF56024 274 471 1.26E-45 T 29-03-2018 MC49_RS15250 8a3b63c11ebd45e4848afef2c8a1508f 486 PIRSF PIRSF000850 300 379 0.0025 T 29-03-2018 MC49_RS15250 8a3b63c11ebd45e4848afef2c8a1508f 486 PIRSF PIRSF000850 367 463 0.13 T 29-03-2018 MC49_RS15250 8a3b63c11ebd45e4848afef2c8a1508f 486 PIRSF PIRSF000850 105 191 2.7 T 29-03-2018 MC49_RS15250 8a3b63c11ebd45e4848afef2c8a1508f 486 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 6 486 3.7E-177 T 29-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 MC49_RS15250 8a3b63c11ebd45e4848afef2c8a1508f 486 Pfam PF13091 PLD-like domain 327 445 3.7E-25 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 MC49_RS15250 8a3b63c11ebd45e4848afef2c8a1508f 486 Pfam PF13091 PLD-like domain 134 243 3.0E-14 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 MC49_RS15250 8a3b63c11ebd45e4848afef2c8a1508f 486 Hamap MF_00190 Cardiolipin synthase A [clsA]. 2 486 49.198 T 29-03-2018 IPR030840 Cardiolipin synthase A GO:0008808|GO:0016780|GO:0032049 MC49_RS15250 8a3b63c11ebd45e4848afef2c8a1508f 486 Pfam PF13396 Phospholipase_D-nuclease N-terminal 25 59 2.2E-7 T 29-03-2018 IPR027379 Cardiolipin synthase N-terminal MC49_RS15250 8a3b63c11ebd45e4848afef2c8a1508f 486 SUPERFAMILY SSF56024 66 315 5.02E-49 T 29-03-2018 MC49_RS11750 f72d83f5f09de775668a9e9e11a6ae0b 299 Hamap MF_00361 NAD kinase [nadK]. 13 294 33.26 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 MC49_RS11750 f72d83f5f09de775668a9e9e11a6ae0b 299 Pfam PF01513 ATP-NAD kinase 15 278 3.8E-74 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 MC49_RS11750 f72d83f5f09de775668a9e9e11a6ae0b 299 SUPERFAMILY SSF111331 14 296 1.16E-91 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain MC49_RS11750 f72d83f5f09de775668a9e9e11a6ae0b 299 Gene3D G3DSA:2.60.200.30 149 271 6.2E-40 T 29-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 MC49_RS11750 f72d83f5f09de775668a9e9e11a6ae0b 299 Gene3D G3DSA:3.40.50.10330 8 148 2.5E-38 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 MC49_RS09070 c984878d5eaf6b01366c676d2f81bacd 296 Pfam PF13247 4Fe-4S dicluster domain 92 188 2.8E-25 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MC49_RS09070 c984878d5eaf6b01366c676d2f81bacd 296 TIGRFAM TIGR01582 FDH-beta: formate dehydrogenase, beta subunit 7 290 9.1E-142 T 29-03-2018 IPR006470 Formate dehydrogenase iron-sulphur subunit, Proteobacteria GO:0015944|GO:0016021|GO:0045333|GO:0051539 MC49_RS09070 c984878d5eaf6b01366c676d2f81bacd 296 Pfam PF09163 Formate dehydrogenase N, transmembrane 246 289 3.3E-19 T 29-03-2018 IPR015246 Formate dehydrogenase, transmembrane MC49_RS09070 c984878d5eaf6b01366c676d2f81bacd 296 Gene3D G3DSA:1.20.5.480 256 291 4.1E-22 T 29-03-2018 MC49_RS09070 c984878d5eaf6b01366c676d2f81bacd 296 Gene3D G3DSA:3.30.70.20 43 113 4.6E-21 T 29-03-2018 MC49_RS09070 c984878d5eaf6b01366c676d2f81bacd 296 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 133 144 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MC49_RS09070 c984878d5eaf6b01366c676d2f81bacd 296 Gene3D G3DSA:3.30.70.20 153 255 1.3E-23 T 29-03-2018 MC49_RS09070 c984878d5eaf6b01366c676d2f81bacd 296 PIRSF PIRSF036298 1 296 6.1E-160 T 29-03-2018 IPR014603 Formate dehydrogenase iron-sulphur subunit GO:0015944|GO:0045333|GO:0051539 MC49_RS09070 c984878d5eaf6b01366c676d2f81bacd 296 Gene3D G3DSA:3.30.70.20 10 42 0.004 T 29-03-2018 MC49_RS09070 c984878d5eaf6b01366c676d2f81bacd 296 Gene3D G3DSA:3.30.70.20 114 152 4.1E-16 T 29-03-2018 MC49_RS09070 c984878d5eaf6b01366c676d2f81bacd 296 SUPERFAMILY SSF54862 28 269 1.88E-70 T 29-03-2018 MC49_RS02390 d91e823fac24423997e03428c83b8794 252 SUPERFAMILY SSF49584 155 246 1.96E-24 T 29-03-2018 IPR016148 Pili assembly chaperone, C-terminal MC49_RS02390 d91e823fac24423997e03428c83b8794 252 PRINTS PR00969 Pili chaperone signature 77 98 9.2E-32 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS02390 d91e823fac24423997e03428c83b8794 252 PRINTS PR00969 Pili chaperone signature 167 182 9.2E-32 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS02390 d91e823fac24423997e03428c83b8794 252 PRINTS PR00969 Pili chaperone signature 107 124 9.2E-32 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS02390 d91e823fac24423997e03428c83b8794 252 PRINTS PR00969 Pili chaperone signature 31 40 9.2E-32 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS02390 d91e823fac24423997e03428c83b8794 252 PRINTS PR00969 Pili chaperone signature 130 145 9.2E-32 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS02390 d91e823fac24423997e03428c83b8794 252 SUPERFAMILY SSF49354 31 149 3.92E-37 T 29-03-2018 IPR008962 PapD-like MC49_RS02390 d91e823fac24423997e03428c83b8794 252 Gene3D G3DSA:2.60.40.10 30 149 9.2E-36 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS02390 d91e823fac24423997e03428c83b8794 252 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 31 148 5.9E-38 T 29-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 MC49_RS02390 d91e823fac24423997e03428c83b8794 252 Gene3D G3DSA:2.60.40.10 152 245 2.9E-22 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS02390 d91e823fac24423997e03428c83b8794 252 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 172 233 1.4E-16 T 29-03-2018 IPR016148 Pili assembly chaperone, C-terminal MC49_RS02390 d91e823fac24423997e03428c83b8794 252 ProSitePatterns PS00635 Gram-negative pili assembly chaperone signature. 106 123 - T 29-03-2018 IPR018046 Pili assembly chaperone, conserved site MC49_RS19000 ad9a8d95d0959d73be8840d00b973ba3 919 SUPERFAMILY SSF52540 12 239 6.63E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS19000 ad9a8d95d0959d73be8840d00b973ba3 919 Pfam PF00005 ABC transporter 294 437 1.4E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS19000 ad9a8d95d0959d73be8840d00b973ba3 919 Pfam PF00005 ABC transporter 28 175 1.5E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS19000 ad9a8d95d0959d73be8840d00b973ba3 919 Pfam PF12698 ABC-2 family transporter protein 574 907 5.2E-41 T 29-03-2018 MC49_RS19000 ad9a8d95d0959d73be8840d00b973ba3 919 Gene3D G3DSA:3.40.1710.10 585 738 2.4E-26 T 29-03-2018 MC49_RS19000 ad9a8d95d0959d73be8840d00b973ba3 919 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS19000 ad9a8d95d0959d73be8840d00b973ba3 919 Gene3D G3DSA:3.40.50.300 9 275 2.4E-60 T 29-03-2018 MC49_RS19000 ad9a8d95d0959d73be8840d00b973ba3 919 Gene3D G3DSA:3.40.50.300 276 546 5.1E-61 T 29-03-2018 MC49_RS19000 ad9a8d95d0959d73be8840d00b973ba3 919 SMART SM00382 37 225 4.2E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS19000 ad9a8d95d0959d73be8840d00b973ba3 919 SMART SM00382 302 493 2.9E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS19000 ad9a8d95d0959d73be8840d00b973ba3 919 SUPERFAMILY SSF52540 267 498 2.96E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS07325 dcd9ba311332ef7edf997eb119929881 440 SUPERFAMILY SSF52418 74 334 9.55E-90 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MC49_RS07325 dcd9ba311332ef7edf997eb119929881 440 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 5 423 8.8E-164 T 29-03-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 MC49_RS07325 dcd9ba311332ef7edf997eb119929881 440 Hamap MF_01628 Thymidine phosphorylase [deoA]. 2 438 46.745 T 29-03-2018 IPR013465 Thymidine phosphorylase GO:0006213|GO:0009032 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181 MC49_RS07325 dcd9ba311332ef7edf997eb119929881 440 SMART SM00941 350 424 7.0E-27 T 29-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MC49_RS07325 dcd9ba311332ef7edf997eb119929881 440 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 113 128 - T 29-03-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MC49_RS07325 dcd9ba311332ef7edf997eb119929881 440 Pfam PF02885 Glycosyl transferase family, helical bundle domain 6 67 1.2E-18 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 MC49_RS07325 dcd9ba311332ef7edf997eb119929881 440 Gene3D G3DSA:3.90.1170.30 342 429 6.3E-26 T 29-03-2018 MC49_RS07325 dcd9ba311332ef7edf997eb119929881 440 SUPERFAMILY SSF54680 338 438 6.54E-29 T 29-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MC49_RS07325 dcd9ba311332ef7edf997eb119929881 440 PIRSF PIRSF000478 1 439 9.1E-152 T 29-03-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MC49_RS07325 dcd9ba311332ef7edf997eb119929881 440 Gene3D G3DSA:1.20.970.10 2 68 1.3E-21 T 29-03-2018 MC49_RS07325 dcd9ba311332ef7edf997eb119929881 440 Pfam PF00591 Glycosyl transferase family, a/b domain 80 309 9.5E-52 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MC49_RS07325 dcd9ba311332ef7edf997eb119929881 440 Gene3D G3DSA:3.40.1030.10 69 341 3.7E-84 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MC49_RS07325 dcd9ba311332ef7edf997eb119929881 440 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 350 423 2.3E-20 T 29-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MC49_RS07325 dcd9ba311332ef7edf997eb119929881 440 TIGRFAM TIGR02643 T_phosphoryl: thymidine phosphorylase 2 438 2.2E-226 T 29-03-2018 IPR013465 Thymidine phosphorylase GO:0006213|GO:0009032 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181 MC49_RS07325 dcd9ba311332ef7edf997eb119929881 440 SUPERFAMILY SSF47648 3 70 6.41E-21 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 MC49_RS06725 d1c0f6631bed5e9aeec2f88ce3243843 369 Pfam PF01381 Helix-turn-helix 25 74 7.1E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS06725 d1c0f6631bed5e9aeec2f88ce3243843 369 SUPERFAMILY SSF47413 15 97 1.07E-20 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS06725 d1c0f6631bed5e9aeec2f88ce3243843 369 Gene3D G3DSA:1.10.260.40 14 89 1.2E-15 T 29-03-2018 MC49_RS06725 d1c0f6631bed5e9aeec2f88ce3243843 369 Pfam PF06114 IrrE N-terminal-like domain 246 331 1.8E-8 T 29-03-2018 IPR010359 IrrE N-terminal-like domain MC49_RS06725 d1c0f6631bed5e9aeec2f88ce3243843 369 SMART SM00530 19 74 2.1E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS04485 19512a9ed3bb5f484873c4a65ec286ee 398 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 10 393 3.7E-162 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MC49_RS04485 19512a9ed3bb5f484873c4a65ec286ee 398 Gene3D G3DSA:3.40.640.10 7 261 2.8E-66 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS04485 19512a9ed3bb5f484873c4a65ec286ee 398 Gene3D G3DSA:3.90.1150.10 263 398 6.7E-58 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS04485 19512a9ed3bb5f484873c4a65ec286ee 398 PIRSF PIRSF001434 1 397 9.5E-159 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MC49_RS04485 19512a9ed3bb5f484873c4a65ec286ee 398 TIGRFAM TIGR01328 met_gam_lyase: methionine gamma-lyase 8 394 3.6E-173 T 29-03-2018 IPR006237 L-methionine gamma-lyase GO:0018826 KEGG: 00270+4.4.1.11|KEGG: 00450+4.4.1.11|KEGG: 00920+4.4.1.2|MetaCyc: PWY-7793 MC49_RS04485 19512a9ed3bb5f484873c4a65ec286ee 398 SUPERFAMILY SSF53383 29 395 1.18E-132 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS03525 70232fc93d371f9dadd5d5d533bfaaeb 246 SUPERFAMILY SSF56655 1 242 1.44E-73 T 29-03-2018 MC49_RS03525 70232fc93d371f9dadd5d5d533bfaaeb 246 TIGRFAM TIGR01331 bisphos_cysQ: 3'(2'),5'-bisphosphate nucleotidase 1 244 8.2E-96 T 29-03-2018 IPR006240 3(2),5 -bisphosphate nucleotidase, bacterial GO:0000287|GO:0016020 KEGG: 00920+3.1.3.7 MC49_RS03525 70232fc93d371f9dadd5d5d533bfaaeb 246 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 80 93 - T 29-03-2018 IPR020583 Inositol monophosphatase, metal-binding site MC49_RS03525 70232fc93d371f9dadd5d5d533bfaaeb 246 Gene3D G3DSA:3.30.540.10 1 150 5.6E-38 T 29-03-2018 MC49_RS03525 70232fc93d371f9dadd5d5d533bfaaeb 246 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 204 218 - T 29-03-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 MC49_RS03525 70232fc93d371f9dadd5d5d533bfaaeb 246 PRINTS PR00377 Inositol monophosphatase superfamily signature 57 73 5.1E-5 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MC49_RS03525 70232fc93d371f9dadd5d5d533bfaaeb 246 PRINTS PR00377 Inositol monophosphatase superfamily signature 80 96 5.1E-5 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MC49_RS03525 70232fc93d371f9dadd5d5d533bfaaeb 246 PRINTS PR00377 Inositol monophosphatase superfamily signature 35 55 5.1E-5 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MC49_RS03525 70232fc93d371f9dadd5d5d533bfaaeb 246 Gene3D G3DSA:3.40.190.80 151 245 5.0E-34 T 29-03-2018 MC49_RS03525 70232fc93d371f9dadd5d5d533bfaaeb 246 Pfam PF00459 Inositol monophosphatase family 6 237 4.3E-48 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MC49_RS02950 4207b6c17b69583e8404ba77b94374e5 210 Pfam PF01411 tRNA synthetases class II (A) 28 57 5.1E-5 T 29-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 MC49_RS02950 4207b6c17b69583e8404ba77b94374e5 210 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 176 198 9.4E-5 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 MC49_RS02950 4207b6c17b69583e8404ba77b94374e5 210 Gene3D G3DSA:3.30.980.10 85 209 1.7E-13 T 29-03-2018 MC49_RS02950 4207b6c17b69583e8404ba77b94374e5 210 SUPERFAMILY SSF55186 85 203 3.01E-21 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 MC49_RS02950 4207b6c17b69583e8404ba77b94374e5 210 SUPERFAMILY SSF50447 1 84 2.79E-14 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain MC49_RS15745 caa7671819c765bb0ba7ecada079955c 300 Gene3D G3DSA:3.40.190.10 179 265 3.0E-11 T 29-03-2018 MC49_RS15745 caa7671819c765bb0ba7ecada079955c 300 SUPERFAMILY SSF53850 88 290 3.57E-31 T 29-03-2018 MC49_RS15745 caa7671819c765bb0ba7ecada079955c 300 Gene3D G3DSA:1.10.10.10 5 84 2.6E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS15745 caa7671819c765bb0ba7ecada079955c 300 Gene3D G3DSA:3.40.190.10 89 178 5.2E-11 T 29-03-2018 MC49_RS15745 caa7671819c765bb0ba7ecada079955c 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 62 7.2E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS15745 caa7671819c765bb0ba7ecada079955c 300 Pfam PF03466 LysR substrate binding domain 88 290 2.9E-27 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS15745 caa7671819c765bb0ba7ecada079955c 300 SUPERFAMILY SSF46785 7 83 4.81E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS01945 27773feb6470bde3063ca85d886d2443 117 SUPERFAMILY SSF81343 2 117 1.05E-46 T 29-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MC49_RS01945 27773feb6470bde3063ca85d886d2443 117 Pfam PF02313 Fumarate reductase subunit D 5 115 7.1E-48 T 29-03-2018 IPR003418 Fumarate reductase, subunit D GO:0006106|GO:0016020 MC49_RS01945 27773feb6470bde3063ca85d886d2443 117 ProDom PD015693 FUMARATE MEMBRANE REDUCTASE D SUBUNIT INNER TRANSMEMBRANE HYDROPHOBIC REDUCTASE POLYPEPTIDE 5 117 4.0E-46 T 29-03-2018 IPR003418 Fumarate reductase, subunit D GO:0006106|GO:0016020 MC49_RS01945 27773feb6470bde3063ca85d886d2443 117 Gene3D G3DSA:1.20.1300.10 1 117 4.4E-25 T 29-03-2018 MC49_RS01945 27773feb6470bde3063ca85d886d2443 117 Hamap MF_00709 Fumarate reductase subunit D [frdD]. 1 117 25.502 T 29-03-2018 IPR003418 Fumarate reductase, subunit D GO:0006106|GO:0016020 MC49_RS01945 27773feb6470bde3063ca85d886d2443 117 PIRSF PIRSF000179 1 117 9.8E-47 T 29-03-2018 IPR003418 Fumarate reductase, subunit D GO:0006106|GO:0016020 MC49_RS00455 8e9f57eb38d4539ab4ef63ff0275e594 164 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 41 53 5.2E-12 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MC49_RS00455 8e9f57eb38d4539ab4ef63ff0275e594 164 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 15 30 5.2E-12 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MC49_RS00455 8e9f57eb38d4539ab4ef63ff0275e594 164 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 118 133 5.2E-12 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MC49_RS00455 8e9f57eb38d4539ab4ef63ff0275e594 164 PIRSF PIRSF001467 1 164 3.9E-30 T 29-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 MC49_RS00455 8e9f57eb38d4539ab4ef63ff0275e594 164 Gene3D G3DSA:2.40.100.10 1 164 2.3E-52 T 29-03-2018 IPR029000 Cyclophilin-like domain MC49_RS00455 8e9f57eb38d4539ab4ef63ff0275e594 164 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 36 53 - T 29-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 MC49_RS00455 8e9f57eb38d4539ab4ef63ff0275e594 164 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 1 161 1.9E-47 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 MC49_RS00455 8e9f57eb38d4539ab4ef63ff0275e594 164 SUPERFAMILY SSF50891 1 162 7.01E-59 T 29-03-2018 IPR029000 Cyclophilin-like domain MC49_RS18750 4819a45548a9125658a98b1064b10456 554 Gene3D G3DSA:3.90.76.10 129 257 1.5E-19 T 29-03-2018 MC49_RS18750 4819a45548a9125658a98b1064b10456 554 Gene3D G3DSA:3.10.105.10 301 476 1.1E-4 T 29-03-2018 MC49_RS18750 4819a45548a9125658a98b1064b10456 554 Pfam PF12793 Sugar transport-related sRNA regulator N-term 5 118 7.9E-40 T 29-03-2018 IPR025370 Transcriptional regulator SgrR, N-terminal HTH domain MC49_RS18750 4819a45548a9125658a98b1064b10456 554 SUPERFAMILY SSF46785 4 56 2.73E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS18750 4819a45548a9125658a98b1064b10456 554 SUPERFAMILY SSF53850 117 551 3.08E-58 T 29-03-2018 MC49_RS18750 4819a45548a9125658a98b1064b10456 554 Gene3D G3DSA:1.10.10.10 2 119 1.1E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS18750 4819a45548a9125658a98b1064b10456 554 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 164 307 7.7E-19 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain MC49_RS18750 4819a45548a9125658a98b1064b10456 554 Gene3D G3DSA:3.40.190.10 258 300 2.1E-6 T 29-03-2018 MC49_RS00550 2c1bc1eddf2c77195286e6633988aea9 159 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 2 155 3.1E-57 T 29-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC MC49_RS00550 2c1bc1eddf2c77195286e6633988aea9 159 PIRSF PIRSF006181 1 159 1.8E-58 T 29-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC MC49_RS00550 2c1bc1eddf2c77195286e6633988aea9 159 Gene3D G3DSA:3.90.960.10 1 159 4.4E-43 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MC49_RS00550 2c1bc1eddf2c77195286e6633988aea9 159 SUPERFAMILY SSF55826 2 155 1.96E-44 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MC49_RS00550 2c1bc1eddf2c77195286e6633988aea9 159 Pfam PF04073 Aminoacyl-tRNA editing domain 32 146 2.6E-24 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MC49_RS10775 4186d8af3ffdf6cf055765e34ec63f9e 294 Gene3D G3DSA:3.40.140.10 40 171 7.2E-26 T 29-03-2018 MC49_RS10775 4186d8af3ffdf6cf055765e34ec63f9e 294 SUPERFAMILY SSF53927 1 147 4.35E-39 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 MC49_RS10775 4186d8af3ffdf6cf055765e34ec63f9e 294 TIGRFAM TIGR01355 cyt_deam_dimer: cytidine deaminase 31 289 6.6E-84 T 29-03-2018 IPR006263 Cytidine deaminase, homodimeric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199 MC49_RS10775 4186d8af3ffdf6cf055765e34ec63f9e 294 Gene3D G3DSA:3.40.140.10 188 293 6.2E-15 T 29-03-2018 MC49_RS10775 4186d8af3ffdf6cf055765e34ec63f9e 294 Pfam PF08211 Cytidine and deoxycytidylate deaminase zinc-binding region 157 277 2.3E-43 T 29-03-2018 IPR013171 Cytidine/deoxycytidylate deaminase, zinc-binding domain GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199 MC49_RS10775 4186d8af3ffdf6cf055765e34ec63f9e 294 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 102 136 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 MC49_RS10775 4186d8af3ffdf6cf055765e34ec63f9e 294 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 55 140 1.7E-11 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain MC49_RS10775 4186d8af3ffdf6cf055765e34ec63f9e 294 SUPERFAMILY SSF53927 154 289 3.46E-37 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 MC49_RS10775 4186d8af3ffdf6cf055765e34ec63f9e 294 Hamap MF_01558 Cytidine deaminase [cdd]. 1 293 46.47 T 29-03-2018 IPR020797 Cytidine deaminase, bacteria GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199 MC49_RS10775 4186d8af3ffdf6cf055765e34ec63f9e 294 PIRSF PIRSF006334 14 294 9.0E-98 T 29-03-2018 MC49_RS17270 14b0924f61f715304d81843163e39e0d 394 Gene3D G3DSA:1.20.1250.20 200 392 1.5E-13 T 29-03-2018 MC49_RS17270 14b0924f61f715304d81843163e39e0d 394 Pfam PF07690 Major Facilitator Superfamily 16 358 2.9E-44 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS17270 14b0924f61f715304d81843163e39e0d 394 Gene3D G3DSA:1.20.1250.20 3 196 3.2E-34 T 29-03-2018 MC49_RS17270 14b0924f61f715304d81843163e39e0d 394 SUPERFAMILY SSF103473 8 388 2.35E-63 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS17270 14b0924f61f715304d81843163e39e0d 394 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 10 386 3.6E-129 T 29-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 MC49_RS15550 76469ebb2b314bc2c4e6868956ac33c7 308 PIRSF PIRSF004976 2 267 7.2E-76 T 29-03-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 MC49_RS15550 76469ebb2b314bc2c4e6868956ac33c7 308 Gene3D G3DSA:3.40.50.620 4 230 1.0E-39 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS15550 76469ebb2b314bc2c4e6868956ac33c7 308 Hamap MF_01850 tRNA 2-thiocytidine biosynthesis protein TtcA [ttcA]. 5 266 57.905 T 29-03-2018 IPR012089 2-thiocytidine tRNA biosynthesis protein, TtcA GO:0008033 MC49_RS15550 76469ebb2b314bc2c4e6868956ac33c7 308 SUPERFAMILY SSF52402 23 252 1.66E-55 T 29-03-2018 MC49_RS15550 76469ebb2b314bc2c4e6868956ac33c7 308 Pfam PF01171 PP-loop family 37 200 2.5E-14 T 29-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 MC49_RS07080 092f9f6ac48dc8fba31cd6aa353658a2 251 SUPERFAMILY SSF53167 4 248 6.28E-72 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MC49_RS07080 092f9f6ac48dc8fba31cd6aa353658a2 251 TIGRFAM TIGR01718 Uridine-psphlse: uridine phosphorylase 4 251 6.4E-119 T 29-03-2018 IPR010058 Uridine phosphorylase GO:0004850|GO:0005737|GO:0009166 KEGG: 00240+2.4.2.3|KEGG: 00983+2.4.2.3|MetaCyc: PWY-5532 MC49_RS07080 092f9f6ac48dc8fba31cd6aa353658a2 251 Pfam PF01048 Phosphorylase superfamily 19 230 5.6E-39 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MC49_RS07080 092f9f6ac48dc8fba31cd6aa353658a2 251 Gene3D G3DSA:3.40.50.1580 1 251 1.4E-54 T 29-03-2018 MC49_RS07080 092f9f6ac48dc8fba31cd6aa353658a2 251 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 64 79 - T 29-03-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 MC49_RS05800 2a29f0a3a8580d9322fd12f7150f7eda 256 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 240 1.9E-90 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS05800 2a29f0a3a8580d9322fd12f7150f7eda 256 Gene3D G3DSA:3.20.20.70 1 256 8.5E-100 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS05800 2a29f0a3a8580d9322fd12f7150f7eda 256 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 249 40.533 T 29-03-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS05800 2a29f0a3a8580d9322fd12f7150f7eda 256 SUPERFAMILY SSF51351 1 249 3.4E-91 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS05800 2a29f0a3a8580d9322fd12f7150f7eda 256 ProSitePatterns PS00171 Triosephosphate isomerase active site. 165 175 - T 29-03-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS05800 2a29f0a3a8580d9322fd12f7150f7eda 256 Pfam PF00121 Triosephosphate isomerase 5 246 8.6E-93 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS13595 8ebb86976d4e2901da26421fc092a4e1 76 Gene3D G3DSA:3.30.1300.30 1 76 8.0E-23 T 29-03-2018 MC49_RS13595 8ebb86976d4e2901da26421fc092a4e1 76 SUPERFAMILY SSF54523 2 76 3.77E-17 T 29-03-2018 MC49_RS13595 8ebb86976d4e2901da26421fc092a4e1 76 Pfam PF03895 YadA-like membrane anchor domain 15 76 5.0E-19 T 29-03-2018 IPR005594 YadA-like, C-terminal MC49_RS05195 54343efceb73a57f727c351b1edc399c 275 SUPERFAMILY SSF52980 11 168 2.73E-60 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MC49_RS05195 54343efceb73a57f727c351b1edc399c 275 Pfam PF08722 TnsA endonuclease N terminal 76 165 2.1E-22 T 29-03-2018 IPR014833 TnsA endonuclease, N-terminal MC49_RS05195 54343efceb73a57f727c351b1edc399c 275 Gene3D G3DSA:3.40.1350.10 7 168 3.6E-46 T 29-03-2018 MC49_RS05195 54343efceb73a57f727c351b1edc399c 275 SUPERFAMILY SSF46785 170 267 4.08E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS05195 54343efceb73a57f727c351b1edc399c 275 Gene3D G3DSA:1.10.10.10 172 260 1.7E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS05195 54343efceb73a57f727c351b1edc399c 275 Pfam PF08721 TnsA endonuclease C terminal 167 246 1.8E-11 T 29-03-2018 IPR014832 TnsA endonuclease C-terminal MC49_RS07835 3e93aebaa8a99ef1688e883ad2a53652 536 SUPERFAMILY SSF161098 287 531 1.31E-28 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS07835 3e93aebaa8a99ef1688e883ad2a53652 536 Gene3D G3DSA:1.10.3720.10 8 270 1.7E-32 T 29-03-2018 MC49_RS07835 3e93aebaa8a99ef1688e883ad2a53652 536 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 75 259 1.2E-11 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS07835 3e93aebaa8a99ef1688e883ad2a53652 536 Gene3D G3DSA:1.10.3720.10 323 535 3.6E-20 T 29-03-2018 MC49_RS07835 3e93aebaa8a99ef1688e883ad2a53652 536 SUPERFAMILY SSF161098 8 264 2.88E-42 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS07835 3e93aebaa8a99ef1688e883ad2a53652 536 TIGRFAM TIGR01253 thiP: thiamine/thiamine pyrophosphate ABC transporter, permease protein 8 527 2.9E-228 T 29-03-2018 IPR005947 Thiamine ABC transporter, permease protein GO:0005215|GO:0015888|GO:0016021 MC49_RS12720 fc627d0242f0568288d60f466c2d03d2 1324 Gene3D G3DSA:3.20.20.220 177 609 2.0E-106 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like MC49_RS12720 fc627d0242f0568288d60f466c2d03d2 1324 Gene3D G3DSA:1.20.5.550 88 136 4.5E-19 T 29-03-2018 IPR024090 Proline dehydrogenase PutA, domain I GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 MC49_RS12720 fc627d0242f0568288d60f466c2d03d2 1324 TIGRFAM TIGR01238 D1pyr5carbox3: delta-1-pyrroline-5-carboxylate dehydrogenase 609 1114 6.1E-225 T 29-03-2018 IPR005933 Delta-1-pyrroline-5-carboxylate dehydrogenase 3 GO:0003842|GO:0006561|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 MC49_RS12720 fc627d0242f0568288d60f466c2d03d2 1324 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 912 923 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 MC49_RS12720 fc627d0242f0568288d60f466c2d03d2 1324 Pfam PF14850 DNA-binding domain of Proline dehydrogenase 147 258 1.2E-45 T 29-03-2018 IPR024082 Proline dehydrogenase PutA, domain II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 MC49_RS12720 fc627d0242f0568288d60f466c2d03d2 1324 Gene3D G3DSA:3.40.605.10 645 903 1.9E-73 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MC49_RS12720 fc627d0242f0568288d60f466c2d03d2 1324 Gene3D G3DSA:1.10.1220.10 3 46 1.9E-8 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 MC49_RS12720 fc627d0242f0568288d60f466c2d03d2 1324 SUPERFAMILY SSF81935 87 260 6.8E-66 T 29-03-2018 IPR024089 Proline dehydrogenase PutA, domain I/II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 MC49_RS12720 fc627d0242f0568288d60f466c2d03d2 1324 Gene3D G3DSA:3.40.309.10 904 1096 3.8E-46 T 29-03-2018 MC49_RS12720 fc627d0242f0568288d60f466c2d03d2 1324 SUPERFAMILY SSF47598 4 44 1.11E-10 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 MC49_RS12720 fc627d0242f0568288d60f466c2d03d2 1324 SUPERFAMILY SSF53720 643 1112 1.83E-128 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MC49_RS12720 fc627d0242f0568288d60f466c2d03d2 1324 PIRSF PIRSF000197 73 1324 0.0 T 29-03-2018 IPR025703 Bifunctional protein PutA GO:0003700|GO:0003842|GO:0004657|GO:0006355|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 MC49_RS12720 fc627d0242f0568288d60f466c2d03d2 1324 Pfam PF01619 Proline dehydrogenase 269 568 9.7E-96 T 29-03-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 MC49_RS12720 fc627d0242f0568288d60f466c2d03d2 1324 Pfam PF00171 Aldehyde dehydrogenase family 661 1111 6.1E-114 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MC49_RS12720 fc627d0242f0568288d60f466c2d03d2 1324 SUPERFAMILY SSF51730 261 617 3.81E-120 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like MC49_RS16100 7ddee8d850faf6dd926a570d70f7c777 668 Gene3D G3DSA:3.40.630.30 360 544 2.1E-13 T 29-03-2018 MC49_RS16100 7ddee8d850faf6dd926a570d70f7c777 668 Pfam PF08351 Domain of unknown function (DUF1726) 61 142 5.8E-7 T 29-03-2018 IPR013562 tRNA(Met) cytidine acetyltransferase TmcA, N-terminal Reactome: R-HSA-6790901 MC49_RS16100 7ddee8d850faf6dd926a570d70f7c777 668 SUPERFAMILY SSF55729 412 540 8.58E-11 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS16100 7ddee8d850faf6dd926a570d70f7c777 668 Hamap MF_01886 tRNA(Met) cytidine acetyltransferase TmcA [tmcA]. 17 653 42.987 T 29-03-2018 IPR024914 tRNA(Met) cytidine acetyltransferase TmcA GO:0000049|GO:0002101|GO:0051391|GO:0051392 KEGG: 00650+2.3.1.19 MC49_RS16100 7ddee8d850faf6dd926a570d70f7c777 668 SUPERFAMILY SSF52540 153 287 1.82E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS16100 7ddee8d850faf6dd926a570d70f7c777 668 Gene3D G3DSA:3.40.50.300 136 319 1.1E-9 T 29-03-2018 MC49_RS16100 7ddee8d850faf6dd926a570d70f7c777 668 Pfam PF13718 GNAT acetyltransferase 2 487 538 1.4E-6 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MC49_RS16100 7ddee8d850faf6dd926a570d70f7c777 668 Pfam PF13718 GNAT acetyltransferase 2 374 484 7.1E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MC49_RS16100 7ddee8d850faf6dd926a570d70f7c777 668 Pfam PF05127 Helicase 192 339 8.6E-37 T 29-03-2018 IPR007807 Helicase domain Reactome: R-HSA-6790901 MC49_RS16100 7ddee8d850faf6dd926a570d70f7c777 668 Pfam PF17176 tRNA-binding domain 542 655 1.0E-27 T 29-03-2018 IPR033442 tRNA(Met) cytidine acetyltransferase TmcA, tRNA-binding domain KEGG: 00650+2.3.1.19 MC49_RS07350 0d09fd7c23986fb273993e1ce77af608 928 Gene3D G3DSA:2.40.170.20 312 928 1.1E-34 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MC49_RS07350 0d09fd7c23986fb273993e1ce77af608 928 SUPERFAMILY SSF56935 119 283 2.15E-52 T 29-03-2018 MC49_RS07350 0d09fd7c23986fb273993e1ce77af608 928 SUPERFAMILY SSF56935 314 630 2.15E-52 T 29-03-2018 MC49_RS07350 0d09fd7c23986fb273993e1ce77af608 928 SUPERFAMILY SSF56935 663 928 2.15E-52 T 29-03-2018 MC49_RS07350 0d09fd7c23986fb273993e1ce77af608 928 Pfam PF07660 Secretin and TonB N terminus short domain 64 112 1.6E-8 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 MC49_RS07350 0d09fd7c23986fb273993e1ce77af608 928 Gene3D G3DSA:2.170.130.10 113 270 1.0E-13 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MC49_RS07350 0d09fd7c23986fb273993e1ce77af608 928 Pfam PF07715 TonB-dependent Receptor Plug Domain 139 262 3.4E-10 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MC49_RS07350 0d09fd7c23986fb273993e1ce77af608 928 SMART SM00965 63 113 4.9E-10 T 29-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 MC49_RS05725 0d538f091ceb23b26f6535dcde6ac919 322 SUPERFAMILY SSF51735 3 153 9.28E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS05725 0d538f091ceb23b26f6535dcde6ac919 322 SUPERFAMILY SSF51735 182 189 9.28E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS05725 0d538f091ceb23b26f6535dcde6ac919 322 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 118 2.5E-13 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 MC49_RS05725 0d538f091ceb23b26f6535dcde6ac919 322 Gene3D G3DSA:3.40.50.720 1 130 1.7E-19 T 29-03-2018 MC49_RS05725 0d538f091ceb23b26f6535dcde6ac919 322 SUPERFAMILY SSF55347 127 292 9.32E-23 T 29-03-2018 MC49_RS05725 0d538f091ceb23b26f6535dcde6ac919 322 Gene3D G3DSA:3.30.360.10 131 322 1.9E-24 T 29-03-2018 MC49_RS09820 b8d591a135b366768488e634395d2cc0 63 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 48 3.0E-20 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 MC49_RS09820 b8d591a135b366768488e634395d2cc0 63 SUPERFAMILY SSF117130 1 54 4.18E-21 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 MC49_RS09820 b8d591a135b366768488e634395d2cc0 63 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 58 2.1E-31 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 MC49_RS09820 b8d591a135b366768488e634395d2cc0 63 Pfam PF02599 Global regulator protein family 1 52 2.8E-27 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 MC49_RS09820 b8d591a135b366768488e634395d2cc0 63 Hamap MF_00167 Carbon storage regulator [csrA]. 1 63 20.811 T 29-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 MC49_RS12555 473c1524f74308c7912806d45966b4b7 319 Gene3D G3DSA:1.10.530.10 146 299 5.0E-33 T 29-03-2018 MC49_RS12555 473c1524f74308c7912806d45966b4b7 319 TIGRFAM TIGR02541 flagell_FlgJ: flagellar rod assembly protein/muramidase FlgJ 5 294 3.1E-98 T 29-03-2018 IPR013377 Peptidoglycan hydrolase FlgJ GO:0016798|GO:0044780 MC49_RS12555 473c1524f74308c7912806d45966b4b7 319 Pfam PF10135 Rod binding protein 43 89 1.3E-14 T 29-03-2018 IPR019301 Flagellar protein FlgJ, N-terminal MC49_RS12555 473c1524f74308c7912806d45966b4b7 319 SMART SM00047 141 295 9.1E-34 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 MC49_RS12555 473c1524f74308c7912806d45966b4b7 319 PRINTS PR01002 Flagellar protein FlgJ signature 46 66 2.2E-68 T 29-03-2018 MC49_RS12555 473c1524f74308c7912806d45966b4b7 319 PRINTS PR01002 Flagellar protein FlgJ signature 67 89 2.2E-68 T 29-03-2018 MC49_RS12555 473c1524f74308c7912806d45966b4b7 319 PRINTS PR01002 Flagellar protein FlgJ signature 235 256 2.2E-68 T 29-03-2018 MC49_RS12555 473c1524f74308c7912806d45966b4b7 319 PRINTS PR01002 Flagellar protein FlgJ signature 21 44 2.2E-68 T 29-03-2018 MC49_RS12555 473c1524f74308c7912806d45966b4b7 319 PRINTS PR01002 Flagellar protein FlgJ signature 147 170 2.2E-68 T 29-03-2018 MC49_RS12555 473c1524f74308c7912806d45966b4b7 319 PRINTS PR01002 Flagellar protein FlgJ signature 191 212 2.2E-68 T 29-03-2018 MC49_RS12555 473c1524f74308c7912806d45966b4b7 319 PRINTS PR01002 Flagellar protein FlgJ signature 257 276 2.2E-68 T 29-03-2018 MC49_RS12555 473c1524f74308c7912806d45966b4b7 319 PRINTS PR01002 Flagellar protein FlgJ signature 171 189 2.2E-68 T 29-03-2018 MC49_RS12555 473c1524f74308c7912806d45966b4b7 319 PRINTS PR01002 Flagellar protein FlgJ signature 213 234 2.2E-68 T 29-03-2018 MC49_RS12555 473c1524f74308c7912806d45966b4b7 319 PRINTS PR01002 Flagellar protein FlgJ signature 277 295 2.2E-68 T 29-03-2018 MC49_RS12555 473c1524f74308c7912806d45966b4b7 319 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 159 295 1.6E-19 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 MC49_RS09795 0174033f930cd5bc4bf081b5afa40eb1 717 Gene3D G3DSA:3.40.50.980 202 375 1.1E-18 T 29-03-2018 MC49_RS09795 0174033f930cd5bc4bf081b5afa40eb1 717 Gene3D G3DSA:3.40.50.980 376 526 1.5E-43 T 29-03-2018 MC49_RS09795 0174033f930cd5bc4bf081b5afa40eb1 717 ProSitePatterns PS00455 Putative AMP-binding domain signature. 370 381 - T 29-03-2018 IPR020845 AMP-binding, conserved site MC49_RS09795 0174033f930cd5bc4bf081b5afa40eb1 717 Pfam PF01553 Acyltransferase 16 137 6.9E-14 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MC49_RS09795 0174033f930cd5bc4bf081b5afa40eb1 717 Pfam PF00501 AMP-binding enzyme 246 619 8.4E-62 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MC49_RS09795 0174033f930cd5bc4bf081b5afa40eb1 717 SUPERFAMILY SSF69593 8 171 4.32E-20 T 29-03-2018 MC49_RS09795 0174033f930cd5bc4bf081b5afa40eb1 717 SUPERFAMILY SSF56801 187 714 4.32E-94 T 29-03-2018 MC49_RS09795 0174033f930cd5bc4bf081b5afa40eb1 717 Gene3D G3DSA:3.30.300.30 614 717 2.0E-10 T 29-03-2018 MC49_RS09795 0174033f930cd5bc4bf081b5afa40eb1 717 SMART SM00563 30 140 7.3E-21 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MC49_RS09795 0174033f930cd5bc4bf081b5afa40eb1 717 Gene3D G3DSA:3.40.1130.10 2 201 1.9E-22 T 29-03-2018 MC49_RS09795 0174033f930cd5bc4bf081b5afa40eb1 717 Gene3D G3DSA:2.30.38.10 527 612 3.5E-13 T 29-03-2018 MC49_RS00995 91caa544bd1ed534415d25e97997c7c7 218 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 2 195 1.2E-78 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 MC49_RS00995 91caa544bd1ed534415d25e97997c7c7 218 Pfam PF02660 Glycerol-3-phosphate acyltransferase 11 184 1.8E-51 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 MC49_RS00995 91caa544bd1ed534415d25e97997c7c7 218 SMART SM01207 10 185 6.5E-87 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 MC49_RS00995 91caa544bd1ed534415d25e97997c7c7 218 Gene3D G3DSA:1.20.1250.20 1 218 6.6E-5 T 29-03-2018 MC49_RS00995 91caa544bd1ed534415d25e97997c7c7 218 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 7 193 18.901 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 MC49_RS18680 fb0a2c833062d949b8564c66859e4a59 597 Pfam PF00905 Penicillin binding protein transpeptidase domain 266 561 1.1E-82 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MC49_RS18680 fb0a2c833062d949b8564c66859e4a59 597 Gene3D G3DSA:3.90.1310.10 42 241 1.3E-43 T 29-03-2018 MC49_RS18680 fb0a2c833062d949b8564c66859e4a59 597 SUPERFAMILY SSF56519 69 240 8.11E-45 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 MC49_RS18680 fb0a2c833062d949b8564c66859e4a59 597 Pfam PF03717 Penicillin-binding Protein dimerisation domain 73 226 3.9E-18 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 MC49_RS18680 fb0a2c833062d949b8564c66859e4a59 597 SUPERFAMILY SSF56601 241 570 4.97E-87 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MC49_RS18680 fb0a2c833062d949b8564c66859e4a59 597 Gene3D G3DSA:3.40.710.10 242 594 7.8E-79 T 29-03-2018 MC49_RS02630 340dad772e80e90c65c9673cd0fd0aad 257 Gene3D G3DSA:3.40.50.300 1 244 5.6E-62 T 29-03-2018 MC49_RS02630 340dad772e80e90c65c9673cd0fd0aad 257 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS02630 340dad772e80e90c65c9673cd0fd0aad 257 SUPERFAMILY SSF52540 4 230 1.26E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS02630 340dad772e80e90c65c9673cd0fd0aad 257 SMART SM00382 29 217 3.1E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS02630 340dad772e80e90c65c9673cd0fd0aad 257 Pfam PF00005 ABC transporter 20 168 8.3E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS13850 d0c46e844804aa72173c3e463c34f9db 501 Gene3D G3DSA:3.40.50.300 264 498 2.4E-35 T 29-03-2018 MC49_RS13850 d0c46e844804aa72173c3e463c34f9db 501 Gene3D G3DSA:3.40.50.300 4 251 2.0E-53 T 29-03-2018 MC49_RS13850 d0c46e844804aa72173c3e463c34f9db 501 ProSitePatterns PS00211 ABC transporters family signature. 404 418 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS13850 d0c46e844804aa72173c3e463c34f9db 501 SUPERFAMILY SSF52540 273 487 4.86E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS13850 d0c46e844804aa72173c3e463c34f9db 501 SUPERFAMILY SSF52540 10 237 8.74E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS13850 d0c46e844804aa72173c3e463c34f9db 501 Pfam PF00005 ABC transporter 26 177 2.2E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS13850 d0c46e844804aa72173c3e463c34f9db 501 Pfam PF00005 ABC transporter 278 431 8.8E-20 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS13850 d0c46e844804aa72173c3e463c34f9db 501 SMART SM00382 285 480 0.0021 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS13850 d0c46e844804aa72173c3e463c34f9db 501 SMART SM00382 35 225 2.4E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS05250 2482afa91bf6640f59413396ce3944c7 580 Gene3D G3DSA:3.40.50.300 108 522 7.1E-29 T 29-03-2018 MC49_RS05250 2482afa91bf6640f59413396ce3944c7 580 Pfam PF01935 Domain of unknown function DUF87 148 407 5.0E-33 T 29-03-2018 IPR002789 Helicase HerA, central domain MC49_RS05250 2482afa91bf6640f59413396ce3944c7 580 SUPERFAMILY SSF52540 147 543 8.31E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS06985 eac155937c955365def9dd706826cc9e 468 Pfam PF03796 DnaB-like helicase C terminal domain 203 459 1.9E-111 T 29-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 MC49_RS06985 eac155937c955365def9dd706826cc9e 468 Gene3D G3DSA:3.40.50.300 184 468 5.9E-65 T 29-03-2018 MC49_RS06985 eac155937c955365def9dd706826cc9e 468 SUPERFAMILY SSF48024 22 133 2.09E-38 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 MC49_RS06985 eac155937c955365def9dd706826cc9e 468 SUPERFAMILY SSF52540 201 272 1.98E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS06985 eac155937c955365def9dd706826cc9e 468 SUPERFAMILY SSF52540 299 453 1.98E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS06985 eac155937c955365def9dd706826cc9e 468 SMART SM00382 220 426 1.8E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS06985 eac155937c955365def9dd706826cc9e 468 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 23 460 2.8E-175 T 29-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 MC49_RS06985 eac155937c955365def9dd706826cc9e 468 Pfam PF00772 DnaB-like helicase N terminal domain 24 125 1.2E-36 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 MC49_RS06985 eac155937c955365def9dd706826cc9e 468 Gene3D G3DSA:1.10.860.10 14 166 1.7E-46 T 29-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal MC49_RS12260 8a1e9a8ec571291fb0652c945a5693f1 360 Gene3D G3DSA:2.40.50.140 277 340 4.1E-6 T 29-03-2018 MC49_RS12260 8a1e9a8ec571291fb0652c945a5693f1 360 Pfam PF00005 ABC transporter 18 164 8.6E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS12260 8a1e9a8ec571291fb0652c945a5693f1 360 SUPERFAMILY SSF50331 239 341 1.15E-11 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal MC49_RS12260 8a1e9a8ec571291fb0652c945a5693f1 360 SUPERFAMILY SSF52540 3 245 4.24E-82 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS12260 8a1e9a8ec571291fb0652c945a5693f1 360 Gene3D G3DSA:3.40.50.300 1 242 8.9E-72 T 29-03-2018 MC49_RS12260 8a1e9a8ec571291fb0652c945a5693f1 360 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS12260 8a1e9a8ec571291fb0652c945a5693f1 360 SMART SM00382 27 214 2.9E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS14980 2de00bd8a2840a7ffa6be260aa594bc3 302 Pfam PF05472 DNA replication terminus site-binding protein (Ter protein) 4 298 3.4E-123 T 29-03-2018 IPR008865 DNA replication terminus site-binding protein GO:0003677|GO:0005737|GO:0006274 MC49_RS14980 2de00bd8a2840a7ffa6be260aa594bc3 302 TIGRFAM TIGR02648 rep_term_tus: DNA replication terminus site-binding protein 4 300 6.2E-109 T 29-03-2018 IPR008865 DNA replication terminus site-binding protein GO:0003677|GO:0005737|GO:0006274 MC49_RS14980 2de00bd8a2840a7ffa6be260aa594bc3 302 Gene3D G3DSA:3.30.54.10 265 300 1.8E-5 T 29-03-2018 MC49_RS14980 2de00bd8a2840a7ffa6be260aa594bc3 302 SUPERFAMILY SSF56596 3 299 5.36E-87 T 29-03-2018 IPR008865 DNA replication terminus site-binding protein GO:0003677|GO:0005737|GO:0006274 MC49_RS14980 2de00bd8a2840a7ffa6be260aa594bc3 302 Gene3D G3DSA:3.50.14.10 198 264 2.2E-14 T 29-03-2018 IPR008865 DNA replication terminus site-binding protein GO:0003677|GO:0005737|GO:0006274 MC49_RS14980 2de00bd8a2840a7ffa6be260aa594bc3 302 Gene3D G3DSA:3.50.14.10 1 197 1.0E-50 T 29-03-2018 IPR008865 DNA replication terminus site-binding protein GO:0003677|GO:0005737|GO:0006274 MC49_RS09335 d3db8155c2338dd3dba03d19e3d0f4fa 174 Gene3D G3DSA:2.30.110.10 3 171 2.2E-34 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MC49_RS09335 d3db8155c2338dd3dba03d19e3d0f4fa 174 TIGRFAM TIGR02296 HpaC: 4-hydroxyphenylacetate 3-monooxygenase, reductase component 11 163 4.2E-67 T 29-03-2018 IPR011982 4-hydroxyphenylacetate 3-monooxygenase, reductase component GO:0016651|GO:0042537|GO:0051287|GO:0055114 KEGG: 00740+1.5.1.36 MC49_RS09335 d3db8155c2338dd3dba03d19e3d0f4fa 174 SMART SM00903 15 162 2.9E-50 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 MC49_RS09335 d3db8155c2338dd3dba03d19e3d0f4fa 174 SUPERFAMILY SSF50475 11 163 6.38E-46 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MC49_RS09335 d3db8155c2338dd3dba03d19e3d0f4fa 174 Pfam PF01613 Flavin reductase like domain 15 163 1.1E-29 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 MC49_RS12165 18f8d9efabdba49695fdc4b729480a8b 141 Pfam PF00334 Nucleoside diphosphate kinase 4 138 7.0E-57 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MC49_RS12165 18f8d9efabdba49695fdc4b729480a8b 141 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 35.775 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MC49_RS12165 18f8d9efabdba49695fdc4b729480a8b 141 Gene3D G3DSA:3.30.70.141 1 140 1.7E-53 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MC49_RS12165 18f8d9efabdba49695fdc4b729480a8b 141 SUPERFAMILY SSF54919 1 140 3.27E-59 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MC49_RS12165 18f8d9efabdba49695fdc4b729480a8b 141 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 29-03-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MC49_RS12165 18f8d9efabdba49695fdc4b729480a8b 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 3.6E-39 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MC49_RS12165 18f8d9efabdba49695fdc4b729480a8b 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 3.6E-39 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MC49_RS12165 18f8d9efabdba49695fdc4b729480a8b 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 3.6E-39 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MC49_RS12165 18f8d9efabdba49695fdc4b729480a8b 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 3.6E-39 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MC49_RS12165 18f8d9efabdba49695fdc4b729480a8b 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 3.6E-39 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MC49_RS12165 18f8d9efabdba49695fdc4b729480a8b 141 SMART SM00562 3 140 1.6E-87 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MC49_RS15665 5007264b193cf4e3cd324f4c820e1085 372 Gene3D G3DSA:3.30.420.40 3 182 3.3E-54 T 29-03-2018 MC49_RS15665 5007264b193cf4e3cd324f4c820e1085 372 Gene3D G3DSA:3.30.420.40 218 370 1.5E-26 T 29-03-2018 MC49_RS15665 5007264b193cf4e3cd324f4c820e1085 372 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 5 366 7.1E-166 T 29-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 MC49_RS15665 5007264b193cf4e3cd324f4c820e1085 372 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 4 367 41.721 T 29-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 MC49_RS15665 5007264b193cf4e3cd324f4c820e1085 372 SUPERFAMILY SSF53067 143 340 5.5E-26 T 29-03-2018 MC49_RS15665 5007264b193cf4e3cd324f4c820e1085 372 SUPERFAMILY SSF53067 66 111 5.5E-26 T 29-03-2018 MC49_RS15665 5007264b193cf4e3cd324f4c820e1085 372 SUPERFAMILY SSF53067 5 36 5.5E-26 T 29-03-2018 MC49_RS08975 f65d8eb48ba1570d1ff80b51e5bc6123 171 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 1 166 6.3E-71 T 29-03-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 MC49_RS08975 f65d8eb48ba1570d1ff80b51e5bc6123 171 Pfam PF00156 Phosphoribosyl transferase domain 6 153 8.7E-26 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MC49_RS08975 f65d8eb48ba1570d1ff80b51e5bc6123 171 Gene3D G3DSA:3.40.50.2020 1 170 3.4E-41 T 29-03-2018 MC49_RS08975 f65d8eb48ba1570d1ff80b51e5bc6123 171 SUPERFAMILY SSF53271 2 166 4.33E-53 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like MC49_RS03810 8c17a1283b70408bdf6dfa4950e427c2 293 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 286 3.7E-160 T 29-03-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 MC49_RS03810 8c17a1283b70408bdf6dfa4950e427c2 293 SUPERFAMILY SSF53448 1 286 1.24E-91 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MC49_RS03810 8c17a1283b70408bdf6dfa4950e427c2 293 Pfam PF00483 Nucleotidyl transferase 2 238 8.6E-71 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MC49_RS03810 8c17a1283b70408bdf6dfa4950e427c2 293 Gene3D G3DSA:3.90.550.10 1 292 2.1E-69 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MC49_RS07260 581effeb087f24e8c5ebffdc5d0c64fe 86 Pfam PF07256 Protein of unknown function (DUF1435) 13 77 7.4E-10 T 29-03-2018 IPR009885 Protein of unknown function DUF1435 MC49_RS01000 8c7eed5ef1b184bab071dca324ca5411 339 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 306 4.6E-128 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MC49_RS01000 8c7eed5ef1b184bab071dca324ca5411 339 SUPERFAMILY SSF53067 1 309 3.33E-44 T 29-03-2018 MC49_RS01000 8c7eed5ef1b184bab071dca324ca5411 339 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 97 116 8.7E-53 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MC49_RS01000 8c7eed5ef1b184bab071dca324ca5411 339 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 131 143 8.7E-53 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MC49_RS01000 8c7eed5ef1b184bab071dca324ca5411 339 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 8.7E-53 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MC49_RS01000 8c7eed5ef1b184bab071dca324ca5411 339 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 76 96 8.7E-53 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MC49_RS01000 8c7eed5ef1b184bab071dca324ca5411 339 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 154 175 8.7E-53 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MC49_RS01000 8c7eed5ef1b184bab071dca324ca5411 339 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 263 272 8.7E-53 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MC49_RS01000 8c7eed5ef1b184bab071dca324ca5411 339 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 331 65.143 T 29-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MC49_RS01000 8c7eed5ef1b184bab071dca324ca5411 339 Gene3D G3DSA:3.30.420.40 145 288 7.6E-20 T 29-03-2018 MC49_RS01000 8c7eed5ef1b184bab071dca324ca5411 339 ProSitePatterns PS01016 Glycoprotease family signature. 96 116 - T 29-03-2018 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 MC49_RS01000 8c7eed5ef1b184bab071dca324ca5411 339 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 3 313 2.6E-137 T 29-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MC49_RS01000 8c7eed5ef1b184bab071dca324ca5411 339 Gene3D G3DSA:3.30.420.40 1 144 3.1E-42 T 29-03-2018 MC49_RS01000 8c7eed5ef1b184bab071dca324ca5411 339 Pfam PF00814 Glycoprotease family 24 306 8.9E-104 T 29-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 MC49_RS09860 460d3e5d038486d9ffb00ee600463e32 430 Pfam PF01595 Domain of unknown function DUF21 11 182 5.1E-49 T 29-03-2018 IPR002550 Domain of unknown function DUF21 MC49_RS09860 460d3e5d038486d9ffb00ee600463e32 430 SMART SM01091 342 420 2.5E-24 T 29-03-2018 IPR005170 Transporter-associated domain MC49_RS09860 460d3e5d038486d9ffb00ee600463e32 430 SUPERFAMILY SSF56176 340 422 4.36E-21 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 MC49_RS09860 460d3e5d038486d9ffb00ee600463e32 430 Gene3D G3DSA:3.10.580.10 185 336 2.6E-18 T 29-03-2018 MC49_RS09860 460d3e5d038486d9ffb00ee600463e32 430 Gene3D G3DSA:3.30.465.10 337 420 8.9E-18 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 MC49_RS09860 460d3e5d038486d9ffb00ee600463e32 430 SUPERFAMILY SSF54631 192 329 3.41E-22 T 29-03-2018 MC49_RS09860 460d3e5d038486d9ffb00ee600463e32 430 Pfam PF03471 Transporter associated domain 343 419 1.5E-18 T 29-03-2018 IPR005170 Transporter-associated domain MC49_RS07275 1b32c3918c906cd3021478efc0515063 337 Gene3D G3DSA:3.40.50.150 160 337 2.2E-30 T 29-03-2018 MC49_RS07275 1b32c3918c906cd3021478efc0515063 337 Hamap MF_01862 Ribosomal RNA small subunit methyltransferase C [rsmC]. 4 336 43.591 T 29-03-2018 IPR023543 rRNA small subunit methyltransferase C GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MC49_RS07275 1b32c3918c906cd3021478efc0515063 337 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 265 271 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MC49_RS07275 1b32c3918c906cd3021478efc0515063 337 Pfam PF05175 Methyltransferase small domain 168 332 8.8E-57 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 MC49_RS07275 1b32c3918c906cd3021478efc0515063 337 Pfam PF08468 Methyltransferase small domain N-terminal 8 162 4.5E-53 T 29-03-2018 IPR013675 Methyltransferase small, N-terminal GO:0006364|GO:0008990 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MC49_RS07275 1b32c3918c906cd3021478efc0515063 337 SUPERFAMILY SSF53335 155 314 8.51E-29 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS00725 0ed5079c79e548244f413eb93b03d70e 110 SUPERFAMILY SSF47781 36 108 6.67E-27 T 29-03-2018 IPR010994 RuvA domain 2-like MC49_RS00725 0ed5079c79e548244f413eb93b03d70e 110 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 45 108 4.2E-25 T 29-03-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain MC49_RS00725 0ed5079c79e548244f413eb93b03d70e 110 Pfam PF12836 Helix-hairpin-helix motif 46 108 4.3E-23 T 29-03-2018 MC49_RS00725 0ed5079c79e548244f413eb93b03d70e 110 Gene3D G3DSA:1.10.150.310 67 110 2.8E-16 T 29-03-2018 MC49_RS00725 0ed5079c79e548244f413eb93b03d70e 110 Gene3D G3DSA:1.10.150.20 20 66 4.5E-12 T 29-03-2018 MC49_RS05640 648c69e4b46450ca19088a83bad896c1 414 Gene3D G3DSA:1.20.120.330 19 130 7.6E-5 T 29-03-2018 MC49_RS05640 648c69e4b46450ca19088a83bad896c1 414 Gene3D G3DSA:2.70.70.10 222 414 2.6E-39 T 29-03-2018 MC49_RS05640 648c69e4b46450ca19088a83bad896c1 414 SUPERFAMILY SSF51261 217 412 5.89E-49 T 29-03-2018 IPR011055 Duplicated hybrid motif MC49_RS05640 648c69e4b46450ca19088a83bad896c1 414 Pfam PF01551 Peptidase family M23 315 408 1.5E-26 T 29-03-2018 IPR016047 Peptidase M23 MC49_RS11910 fc572489524807d6ba0c69ae110ddef7 265 Gene3D G3DSA:1.10.10.60 165 263 2.0E-6 T 29-03-2018 MC49_RS11910 fc572489524807d6ba0c69ae110ddef7 265 SUPERFAMILY SSF46689 210 262 4.35E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS11155 caff8d206a2dec925bb0c3875d705b28 71 Gene3D G3DSA:2.40.50.140 1 71 3.3E-17 T 29-03-2018 MC49_RS11155 caff8d206a2dec925bb0c3875d705b28 71 SUPERFAMILY SSF50249 5 70 1.22E-16 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS11155 caff8d206a2dec925bb0c3875d705b28 71 SMART SM00357 7 71 7.8E-9 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 MC49_RS11155 caff8d206a2dec925bb0c3875d705b28 71 PRINTS PR00050 Cold shock protein signature 8 23 1.6E-10 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MC49_RS11155 caff8d206a2dec925bb0c3875d705b28 71 PRINTS PR00050 Cold shock protein signature 29 38 1.6E-10 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MC49_RS11155 caff8d206a2dec925bb0c3875d705b28 71 PRINTS PR00050 Cold shock protein signature 44 62 1.6E-10 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MC49_RS11155 caff8d206a2dec925bb0c3875d705b28 71 Pfam PF00313 'Cold-shock' DNA-binding domain 8 69 6.9E-15 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MC49_RS11155 caff8d206a2dec925bb0c3875d705b28 71 PIRSF PIRSF002599 1 71 5.7E-15 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 MC49_RS06010 32a6857ba30c5921ec56bbffa82935a4 469 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 14 95 4.0E-30 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MC49_RS06010 32a6857ba30c5921ec56bbffa82935a4 469 Gene3D G3DSA:3.10.20.70 2 104 2.5E-26 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MC49_RS06010 32a6857ba30c5921ec56bbffa82935a4 469 ProSitePatterns PS00180 Glutamine synthetase signature 1. 50 68 - T 29-03-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 MC49_RS06010 32a6857ba30c5921ec56bbffa82935a4 469 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 4 468 7.6E-210 T 29-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MC49_RS06010 32a6857ba30c5921ec56bbffa82935a4 469 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 259 274 - T 29-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 MC49_RS06010 32a6857ba30c5921ec56bbffa82935a4 469 Pfam PF00120 Glutamine synthetase, catalytic domain 103 466 4.2E-136 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MC49_RS06010 32a6857ba30c5921ec56bbffa82935a4 469 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 386 398 - T 29-03-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MC49_RS06010 32a6857ba30c5921ec56bbffa82935a4 469 SMART SM01230 102 379 2.9E-151 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MC49_RS06010 32a6857ba30c5921ec56bbffa82935a4 469 Gene3D G3DSA:3.30.590.10 105 457 1.9E-121 T 29-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 MC49_RS06010 32a6857ba30c5921ec56bbffa82935a4 469 SUPERFAMILY SSF55931 102 468 9.42E-139 T 29-03-2018 MC49_RS06010 32a6857ba30c5921ec56bbffa82935a4 469 SUPERFAMILY SSF54368 3 100 2.62E-34 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MC49_RS00585 4b96dac9ae8d78ff3e8d831005c3185d 329 Gene3D G3DSA:3.30.1890.10 52 293 4.1E-22 T 29-03-2018 MC49_RS00585 4b96dac9ae8d78ff3e8d831005c3185d 329 SUPERFAMILY SSF160355 51 295 2.09E-29 T 29-03-2018 MC49_RS00585 4b96dac9ae8d78ff3e8d831005c3185d 329 Pfam PF02706 Chain length determinant protein 13 106 1.7E-15 T 29-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 MC49_RS15495 99b1b2e63e82f30118dc844898263604 110 Pfam PF00893 Small Multidrug Resistance protein 4 94 1.2E-25 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 MC49_RS15495 99b1b2e63e82f30118dc844898263604 110 SUPERFAMILY SSF103481 6 106 3.4E-19 T 29-03-2018 MC49_RS11530 f37b320f33809285c93c82aaebfd456d 337 Gene3D G3DSA:3.60.110.10 8 305 4.7E-63 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MC49_RS11530 f37b320f33809285c93c82aaebfd456d 337 SUPERFAMILY SSF56317 8 181 1.16E-59 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MC49_RS11530 f37b320f33809285c93c82aaebfd456d 337 SUPERFAMILY SSF56317 212 308 1.16E-59 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MC49_RS11530 f37b320f33809285c93c82aaebfd456d 337 Pfam PF00795 Carbon-nitrogen hydrolase 10 284 4.9E-38 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 MC49_RS04295 51c4d9bf2b85f3a9365d213062ce3f4f 257 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 44 212 5.6E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS04295 51c4d9bf2b85f3a9365d213062ce3f4f 257 SUPERFAMILY SSF161098 21 209 3.92E-42 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS04295 51c4d9bf2b85f3a9365d213062ce3f4f 257 Gene3D G3DSA:1.10.3720.10 2 229 1.0E-40 T 29-03-2018 MC49_RS04295 51c4d9bf2b85f3a9365d213062ce3f4f 257 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 23 114 3.1E-18 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 MC49_RS11135 de4677e1622066af1c2cb3696ca629f1 94 TIGRFAM TIGR00988 hip: integration host factor, beta subunit 1 93 8.1E-51 T 29-03-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 MC49_RS11135 de4677e1622066af1c2cb3696ca629f1 94 Hamap MF_00381 Integration host factor subunit beta [ihfB]. 1 94 30.485 T 29-03-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 MC49_RS11135 de4677e1622066af1c2cb3696ca629f1 94 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 1.5E-19 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MC49_RS11135 de4677e1622066af1c2cb3696ca629f1 94 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 1.5E-19 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MC49_RS11135 de4677e1622066af1c2cb3696ca629f1 94 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 1.5E-19 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MC49_RS11135 de4677e1622066af1c2cb3696ca629f1 94 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 29-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 MC49_RS11135 de4677e1622066af1c2cb3696ca629f1 94 Pfam PF00216 Bacterial DNA-binding protein 1 91 5.3E-30 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MC49_RS11135 de4677e1622066af1c2cb3696ca629f1 94 Gene3D G3DSA:4.10.520.10 1 94 1.4E-31 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 MC49_RS11135 de4677e1622066af1c2cb3696ca629f1 94 SMART SM00411 1 91 4.7E-42 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MC49_RS11135 de4677e1622066af1c2cb3696ca629f1 94 SUPERFAMILY SSF47729 1 91 3.97E-30 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 MC49_RS03730 bf6ef7aa187f0fbc09ef36626c36496c 105 Gene3D G3DSA:3.30.920.10 1 105 9.7E-33 T 29-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 MC49_RS03730 bf6ef7aa187f0fbc09ef36626c36496c 105 ProSitePatterns PS01344 Frataxin family signature. 50 64 - T 29-03-2018 IPR020895 Frataxin conserved site Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 MC49_RS03730 bf6ef7aa187f0fbc09ef36626c36496c 105 Hamap MF_00142 Protein CyaY [cyaY]. 1 105 27.97 T 29-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 MC49_RS03730 bf6ef7aa187f0fbc09ef36626c36496c 105 TIGRFAM TIGR03421 FeS_CyaY: iron donor protein CyaY 2 105 5.8E-43 T 29-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 MC49_RS03730 bf6ef7aa187f0fbc09ef36626c36496c 105 Pfam PF01491 Frataxin-like domain 1 102 9.4E-30 T 29-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 MC49_RS03730 bf6ef7aa187f0fbc09ef36626c36496c 105 SUPERFAMILY SSF55387 1 105 4.36E-38 T 29-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 MC49_RS03730 bf6ef7aa187f0fbc09ef36626c36496c 105 SMART SM01219 1 104 1.3E-54 T 29-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 MC49_RS06165 f7053bcda5edb75d4efc2f1b8ad39eb3 68 SUPERFAMILY SSF55331 2 66 2.26E-22 T 29-03-2018 IPR014347 Tautomerase/MIF superfamily MC49_RS06165 f7053bcda5edb75d4efc2f1b8ad39eb3 68 TIGRFAM TIGR00013 taut: 4-oxalocrotonate tautomerase family enzyme 1 63 1.7E-28 T 29-03-2018 IPR018191 4-oxalocrotonate tautomerase, Pseudomonas-type GO:0006725|GO:0016853 MC49_RS06165 f7053bcda5edb75d4efc2f1b8ad39eb3 68 Gene3D G3DSA:3.30.429.10 2 66 1.9E-27 T 29-03-2018 MC49_RS06165 f7053bcda5edb75d4efc2f1b8ad39eb3 68 Pfam PF01361 Tautomerase enzyme 2 61 3.0E-24 T 29-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 MC49_RS14005 2307165ed0096f18dab0415b17029681 576 SMART SM01016 5 87 3.3E-28 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 MC49_RS14005 2307165ed0096f18dab0415b17029681 576 Gene3D G3DSA:3.30.1360.70 1 106 3.0E-27 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 MC49_RS14005 2307165ed0096f18dab0415b17029681 576 PRINTS PR01038 Arginyl-tRNA synthetase signature 153 166 4.8E-25 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MC49_RS14005 2307165ed0096f18dab0415b17029681 576 PRINTS PR01038 Arginyl-tRNA synthetase signature 303 324 4.8E-25 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MC49_RS14005 2307165ed0096f18dab0415b17029681 576 PRINTS PR01038 Arginyl-tRNA synthetase signature 129 145 4.8E-25 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MC49_RS14005 2307165ed0096f18dab0415b17029681 576 PRINTS PR01038 Arginyl-tRNA synthetase signature 114 129 4.8E-25 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MC49_RS14005 2307165ed0096f18dab0415b17029681 576 Pfam PF00750 tRNA synthetases class I (R) 97 446 1.6E-161 T 29-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 MC49_RS14005 2307165ed0096f18dab0415b17029681 576 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 3 576 7.6E-200 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MC49_RS14005 2307165ed0096f18dab0415b17029681 576 SUPERFAMILY SSF52374 108 453 4.07E-93 T 29-03-2018 MC49_RS14005 2307165ed0096f18dab0415b17029681 576 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 7 87 3.3E-21 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 MC49_RS14005 2307165ed0096f18dab0415b17029681 576 Gene3D G3DSA:3.40.50.620 109 440 9.7E-56 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS14005 2307165ed0096f18dab0415b17029681 576 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 122 133 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS14005 2307165ed0096f18dab0415b17029681 576 SUPERFAMILY SSF55190 2 101 3.14E-23 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 MC49_RS14005 2307165ed0096f18dab0415b17029681 576 SMART SM00836 460 576 2.0E-37 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 MC49_RS14005 2307165ed0096f18dab0415b17029681 576 Gene3D G3DSA:1.10.730.10 441 576 1.5E-43 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS14005 2307165ed0096f18dab0415b17029681 576 Hamap MF_00123 Arginine--tRNA ligase [argS]. 5 576 28.334 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MC49_RS14005 2307165ed0096f18dab0415b17029681 576 Pfam PF05746 DALR anticodon binding domain 460 576 5.8E-34 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 MC49_RS14005 2307165ed0096f18dab0415b17029681 576 SUPERFAMILY SSF47323 454 576 1.57E-34 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS11215 b21700cfe26a8b01bd2ab678fc1874de 215 SMART SM00849 12 192 1.3E-38 T 29-03-2018 IPR001279 Metallo-beta-lactamase MC49_RS11215 b21700cfe26a8b01bd2ab678fc1874de 215 SUPERFAMILY SSF56281 1 209 2.88E-59 T 29-03-2018 IPR001279 Metallo-beta-lactamase MC49_RS11215 b21700cfe26a8b01bd2ab678fc1874de 215 Pfam PF00753 Metallo-beta-lactamase superfamily 9 192 5.3E-32 T 29-03-2018 IPR001279 Metallo-beta-lactamase MC49_RS11215 b21700cfe26a8b01bd2ab678fc1874de 215 Gene3D G3DSA:3.60.15.10 1 213 2.7E-45 T 29-03-2018 IPR001279 Metallo-beta-lactamase MC49_RS02210 3d922d91b02028eec45e39d12e99eba8 172 SUPERFAMILY SSF141452 3 168 5.23E-39 T 29-03-2018 IPR008514 Type VI secretion system effector, Hcp MC49_RS02210 3d922d91b02028eec45e39d12e99eba8 172 Pfam PF05638 Type VI secretion system effector, Hcp 6 155 1.2E-32 T 29-03-2018 IPR008514 Type VI secretion system effector, Hcp MC49_RS02210 3d922d91b02028eec45e39d12e99eba8 172 TIGRFAM TIGR03344 VI_effect_Hcp1: type VI secretion system effector, Hcp1 family 1 168 8.9E-65 T 29-03-2018 IPR008514 Type VI secretion system effector, Hcp MC49_RS02210 3d922d91b02028eec45e39d12e99eba8 172 Gene3D G3DSA:2.30.110.20 2 172 1.5E-50 T 29-03-2018 IPR008514 Type VI secretion system effector, Hcp MC49_RS18135 183df0bb367dacee5998552552c7ffb9 386 Gene3D G3DSA:1.20.1250.20 4 186 1.1E-12 T 29-03-2018 MC49_RS18135 183df0bb367dacee5998552552c7ffb9 386 SUPERFAMILY SSF103473 14 379 1.06E-37 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS18135 183df0bb367dacee5998552552c7ffb9 386 Pfam PF07690 Major Facilitator Superfamily 19 344 4.4E-24 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS18135 183df0bb367dacee5998552552c7ffb9 386 Gene3D G3DSA:1.20.1250.20 193 384 4.4E-16 T 29-03-2018 MC49_RS17375 aa5d36e7f0cf80f8ad5c3c18f6914b37 393 Pfam PF07690 Major Facilitator Superfamily 12 345 5.4E-27 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS17375 aa5d36e7f0cf80f8ad5c3c18f6914b37 393 Gene3D G3DSA:1.20.1250.20 3 194 1.1E-24 T 29-03-2018 MC49_RS17375 aa5d36e7f0cf80f8ad5c3c18f6914b37 393 SUPERFAMILY SSF103473 7 389 9.68E-45 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS17375 aa5d36e7f0cf80f8ad5c3c18f6914b37 393 Gene3D G3DSA:1.20.1250.20 195 393 3.6E-12 T 29-03-2018 MC49_RS05600 8912c800575ebb0c86173e4b2392e603 375 SUPERFAMILY SSF53756 5 372 1.05E-69 T 29-03-2018 MC49_RS05600 8912c800575ebb0c86173e4b2392e603 375 Gene3D G3DSA:3.40.50.2000 1 191 5.3E-10 T 29-03-2018 MC49_RS05600 8912c800575ebb0c86173e4b2392e603 375 Pfam PF00534 Glycosyl transferases group 1 196 352 1.1E-23 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 MC49_RS05600 8912c800575ebb0c86173e4b2392e603 375 Gene3D G3DSA:3.40.50.2000 192 354 1.9E-32 T 29-03-2018 MC49_RS05600 8912c800575ebb0c86173e4b2392e603 375 Pfam PF13439 Glycosyltransferase Family 4 17 182 2.0E-20 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 MC49_RS08375 edfb16a655caf12443e6f7ccc4a09781 511 SUPERFAMILY SSF52540 1 229 4.07E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS08375 edfb16a655caf12443e6f7ccc4a09781 511 Gene3D G3DSA:3.40.50.300 2 239 5.8E-49 T 29-03-2018 MC49_RS08375 edfb16a655caf12443e6f7ccc4a09781 511 SUPERFAMILY SSF52317 254 459 5.2E-34 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MC49_RS08375 edfb16a655caf12443e6f7ccc4a09781 511 Pfam PF13500 AAA domain 5 227 4.1E-21 T 29-03-2018 MC49_RS08375 edfb16a655caf12443e6f7ccc4a09781 511 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 506 182.204 T 29-03-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 MC49_RS08375 edfb16a655caf12443e6f7ccc4a09781 511 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 253 451 2.0E-55 T 29-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 MC49_RS08375 edfb16a655caf12443e6f7ccc4a09781 511 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 5 498 7.4E-158 T 29-03-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 MC49_RS08375 edfb16a655caf12443e6f7ccc4a09781 511 Gene3D G3DSA:3.40.50.880 252 501 2.0E-26 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MC49_RS12345 6a6cbcbd12cf2a7ad826ba90ab82697f 245 Gene3D G3DSA:3.30.70.20 114 152 6.8E-20 T 29-03-2018 MC49_RS12345 6a6cbcbd12cf2a7ad826ba90ab82697f 245 SUPERFAMILY SSF54862 42 222 6.7E-67 T 29-03-2018 MC49_RS12345 6a6cbcbd12cf2a7ad826ba90ab82697f 245 Gene3D G3DSA:3.30.70.20 57 113 4.1E-18 T 29-03-2018 MC49_RS12345 6a6cbcbd12cf2a7ad826ba90ab82697f 245 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 132 143 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MC49_RS12345 6a6cbcbd12cf2a7ad826ba90ab82697f 245 Pfam PF13247 4Fe-4S dicluster domain 94 187 2.6E-29 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MC49_RS12345 6a6cbcbd12cf2a7ad826ba90ab82697f 245 Gene3D G3DSA:3.30.70.20 30 56 0.024 T 29-03-2018 MC49_RS12345 6a6cbcbd12cf2a7ad826ba90ab82697f 245 Gene3D G3DSA:3.30.70.20 153 238 1.3E-22 T 29-03-2018 MC49_RS04635 8b5366ff54048e65503f6828be6f2065 206 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 89 3.3E-30 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MC49_RS04635 8b5366ff54048e65503f6828be6f2065 206 PRINTS PR01703 Manganese superoxide dismutase signature 124 132 9.3E-27 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MC49_RS04635 8b5366ff54048e65503f6828be6f2065 206 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 9.3E-27 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MC49_RS04635 8b5366ff54048e65503f6828be6f2065 206 PRINTS PR01703 Manganese superoxide dismutase signature 166 178 9.3E-27 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MC49_RS04635 8b5366ff54048e65503f6828be6f2065 206 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 9.3E-27 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MC49_RS04635 8b5366ff54048e65503f6828be6f2065 206 PRINTS PR01703 Manganese superoxide dismutase signature 73 86 9.3E-27 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MC49_RS04635 8b5366ff54048e65503f6828be6f2065 206 Gene3D G3DSA:1.10.287.990 20 90 1.0E-28 T 29-03-2018 MC49_RS04635 8b5366ff54048e65503f6828be6f2065 206 SUPERFAMILY SSF54719 95 204 7.33E-45 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MC49_RS04635 8b5366ff54048e65503f6828be6f2065 206 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 168 175 - T 29-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MC49_RS04635 8b5366ff54048e65503f6828be6f2065 206 SUPERFAMILY SSF46609 1 90 1.7E-34 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MC49_RS04635 8b5366ff54048e65503f6828be6f2065 206 PIRSF PIRSF000349 1 206 2.4E-77 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MC49_RS04635 8b5366ff54048e65503f6828be6f2065 206 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 96 201 1.1E-39 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 MC49_RS05075 0a5d858ae32ea391fe848a992d9e5f67 308 PRINTS PR00990 Ribokinase signature 35 54 2.6E-36 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MC49_RS05075 0a5d858ae32ea391fe848a992d9e5f67 308 PRINTS PR00990 Ribokinase signature 175 190 2.6E-36 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MC49_RS05075 0a5d858ae32ea391fe848a992d9e5f67 308 PRINTS PR00990 Ribokinase signature 8 29 2.6E-36 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MC49_RS05075 0a5d858ae32ea391fe848a992d9e5f67 308 PRINTS PR00990 Ribokinase signature 219 230 2.6E-36 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MC49_RS05075 0a5d858ae32ea391fe848a992d9e5f67 308 PRINTS PR00990 Ribokinase signature 107 120 2.6E-36 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MC49_RS05075 0a5d858ae32ea391fe848a992d9e5f67 308 Gene3D G3DSA:3.40.1190.20 1 308 9.9E-85 T 29-03-2018 IPR029056 Ribokinase-like MC49_RS05075 0a5d858ae32ea391fe848a992d9e5f67 308 SUPERFAMILY SSF53613 5 304 6.39E-86 T 29-03-2018 IPR029056 Ribokinase-like MC49_RS05075 0a5d858ae32ea391fe848a992d9e5f67 308 Pfam PF00294 pfkB family carbohydrate kinase 5 296 1.6E-73 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB MC49_RS05075 0a5d858ae32ea391fe848a992d9e5f67 308 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 248 261 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MC49_RS05075 0a5d858ae32ea391fe848a992d9e5f67 308 Hamap MF_01987 Ribokinase [rbsK]. 4 303 26.374 T 29-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 MC49_RS05075 0a5d858ae32ea391fe848a992d9e5f67 308 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 7 301 2.8E-109 T 29-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 MC49_RS05075 0a5d858ae32ea391fe848a992d9e5f67 308 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 40 64 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MC49_RS17240 3ddd8fd07facf95ef48bd2b8c1f42ca4 190 Hamap MF_00646 Elongation factor P-like protein [yeiP]. 2 189 43.035 T 29-03-2018 IPR011897 Translation elongation factor P-like, YeiP MC49_RS17240 3ddd8fd07facf95ef48bd2b8c1f42ca4 190 Gene3D G3DSA:2.40.50.140 133 188 3.8E-20 T 29-03-2018 MC49_RS17240 3ddd8fd07facf95ef48bd2b8c1f42ca4 190 SMART SM01185 69 125 4.2E-13 T 29-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 MC49_RS17240 3ddd8fd07facf95ef48bd2b8c1f42ca4 190 SUPERFAMILY SSF50104 1 64 1.02E-10 T 29-03-2018 IPR008991 Translation protein SH3-like domain MC49_RS17240 3ddd8fd07facf95ef48bd2b8c1f42ca4 190 SUPERFAMILY SSF50249 67 130 1.59E-10 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS17240 3ddd8fd07facf95ef48bd2b8c1f42ca4 190 SUPERFAMILY SSF50249 132 189 3.43E-14 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS17240 3ddd8fd07facf95ef48bd2b8c1f42ca4 190 ProSitePatterns PS01275 Elongation factor P signature. 154 173 - T 29-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site MC49_RS17240 3ddd8fd07facf95ef48bd2b8c1f42ca4 190 Pfam PF09285 Elongation factor P, C-terminal 133 188 4.3E-18 T 29-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 MC49_RS17240 3ddd8fd07facf95ef48bd2b8c1f42ca4 190 PIRSF PIRSF005901 1 190 1.7E-60 T 29-03-2018 IPR020599 Translation elongation factor P/YeiP MC49_RS17240 3ddd8fd07facf95ef48bd2b8c1f42ca4 190 Gene3D G3DSA:2.40.50.140 66 131 3.8E-15 T 29-03-2018 MC49_RS17240 3ddd8fd07facf95ef48bd2b8c1f42ca4 190 Pfam PF01132 Elongation factor P (EF-P) OB domain 70 125 8.5E-13 T 29-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 MC49_RS17240 3ddd8fd07facf95ef48bd2b8c1f42ca4 190 Gene3D G3DSA:2.30.30.30 2 63 9.8E-15 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 MC49_RS17240 3ddd8fd07facf95ef48bd2b8c1f42ca4 190 TIGRFAM TIGR02178 yeiP: elongation factor P-like protein YeiP 3 189 2.2E-94 T 29-03-2018 IPR011897 Translation elongation factor P-like, YeiP MC49_RS17240 3ddd8fd07facf95ef48bd2b8c1f42ca4 190 SMART SM00841 133 188 1.4E-25 T 29-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 MC49_RS17240 3ddd8fd07facf95ef48bd2b8c1f42ca4 190 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 61 4.8E-16 T 29-03-2018 IPR013185 Translation elongation factor, KOW-like MC49_RS18350 8541442fd226a3f11677a04b6425e102 210 Gene3D G3DSA:1.10.357.10 77 208 1.6E-17 T 29-03-2018 MC49_RS18350 8541442fd226a3f11677a04b6425e102 210 Pfam PF16925 Bacterial transcriptional repressor C-terminal 95 208 9.9E-43 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MC49_RS18350 8541442fd226a3f11677a04b6425e102 210 SUPERFAMILY SSF48498 95 208 2.89E-22 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MC49_RS18350 8541442fd226a3f11677a04b6425e102 210 SUPERFAMILY SSF46689 20 91 6.16E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS18350 8541442fd226a3f11677a04b6425e102 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 68 7.8E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS18350 8541442fd226a3f11677a04b6425e102 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 3.8E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS18350 8541442fd226a3f11677a04b6425e102 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 3.8E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS18350 8541442fd226a3f11677a04b6425e102 210 Gene3D G3DSA:1.10.10.60 2 76 3.2E-11 T 29-03-2018 MC49_RS08755 3b7b9354f9574b30c55c46b17593db24 409 ProSitePatterns PS00216 Sugar transport proteins signature 1. 277 292 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MC49_RS08755 3b7b9354f9574b30c55c46b17593db24 409 ProSitePatterns PS00217 Sugar transport proteins signature 2. 114 139 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MC49_RS08755 3b7b9354f9574b30c55c46b17593db24 409 SUPERFAMILY SSF103473 13 406 4.84E-81 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS08755 3b7b9354f9574b30c55c46b17593db24 409 Pfam PF07690 Major Facilitator Superfamily 28 271 5.3E-35 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS08755 3b7b9354f9574b30c55c46b17593db24 409 Gene3D G3DSA:1.20.1250.20 207 409 8.8E-29 T 29-03-2018 MC49_RS08755 3b7b9354f9574b30c55c46b17593db24 409 Gene3D G3DSA:1.20.1250.20 11 206 7.3E-37 T 29-03-2018 MC49_RS12535 af65fba941ecebf5c4b4685907ca8326 251 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 29-03-2018 IPR019776 Flagellar basal body rod protein, conserved site MC49_RS12535 af65fba941ecebf5c4b4685907ca8326 251 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 171 247 1.7E-21 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain MC49_RS12535 af65fba941ecebf5c4b4685907ca8326 251 Pfam PF00460 Flagella basal body rod protein 5 35 8.4E-10 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 MC49_RS12535 af65fba941ecebf5c4b4685907ca8326 251 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 114 7.6E-31 T 29-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G MC49_RS12535 af65fba941ecebf5c4b4685907ca8326 251 SUPERFAMILY SSF117143 78 209 7.19E-14 T 29-03-2018 MC49_RS09085 abc0faa0f29e2d4bfe899321d457e90b 806 Gene3D G3DSA:2.40.40.20 669 806 6.8E-35 T 29-03-2018 MC49_RS09085 abc0faa0f29e2d4bfe899321d457e90b 806 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 66 119 1.5E-7 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS09085 abc0faa0f29e2d4bfe899321d457e90b 806 Gene3D G3DSA:3.90.55.10 537 609 1.5E-12 T 29-03-2018 MC49_RS09085 abc0faa0f29e2d4bfe899321d457e90b 806 Pfam PF01568 Molydopterin dinucleotide binding domain 687 797 1.4E-23 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 MC49_RS09085 abc0faa0f29e2d4bfe899321d457e90b 806 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 514 531 - T 29-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 MC49_RS09085 abc0faa0f29e2d4bfe899321d457e90b 806 Pfam PF00384 Molybdopterin oxidoreductase 122 571 6.9E-74 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS09085 abc0faa0f29e2d4bfe899321d457e90b 806 TIGRFAM TIGR02166 dmsA_ynfE: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family 18 806 0.0 T 29-03-2018 IPR011888 Anaerobic dimethyl sulphoxide reductase, subunit A, DmsA/YnfE GO:0009389|GO:0030151|GO:0051539|GO:0055114 MC49_RS09085 abc0faa0f29e2d4bfe899321d457e90b 806 Gene3D G3DSA:3.40.228.10 610 668 7.7E-6 T 29-03-2018 MC49_RS09085 abc0faa0f29e2d4bfe899321d457e90b 806 SUPERFAMILY SSF53706 65 689 8.11E-159 T 29-03-2018 MC49_RS09085 abc0faa0f29e2d4bfe899321d457e90b 806 Gene3D G3DSA:3.40.228.10 207 428 4.5E-62 T 29-03-2018 MC49_RS09085 abc0faa0f29e2d4bfe899321d457e90b 806 SMART SM00926 60 119 3.0E-10 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS09085 abc0faa0f29e2d4bfe899321d457e90b 806 SUPERFAMILY SSF50692 640 806 1.81E-37 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain MC49_RS09085 abc0faa0f29e2d4bfe899321d457e90b 806 Gene3D G3DSA:2.20.25.90 53 124 8.3E-15 T 29-03-2018 MC49_RS12980 7e53c6c6f75e4953669d1c3adbbc0001 402 Pfam PF12323 Helix-turn-helix domain 4 48 4.5E-13 T 29-03-2018 IPR021027 Transposase, putative, helix-turn-helix domain MC49_RS12980 7e53c6c6f75e4953669d1c3adbbc0001 402 Pfam PF07282 Putative transposase DNA-binding domain 304 371 7.5E-25 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal MC49_RS12980 7e53c6c6f75e4953669d1c3adbbc0001 402 Pfam PF01385 Probable transposase 162 275 2.3E-30 T 29-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 MC49_RS12980 7e53c6c6f75e4953669d1c3adbbc0001 402 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 244 331 8.8E-11 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal MC49_RS03680 1475b921609c7a8e73bf27f6929defec 608 SUPERFAMILY SSF52540 208 454 2.02E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS03680 1475b921609c7a8e73bf27f6929defec 608 SMART SM00956 411 514 1.3E-56 T 29-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 MC49_RS03680 1475b921609c7a8e73bf27f6929defec 608 SUPERFAMILY SSF47819 530 603 5.01E-25 T 29-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 MC49_RS03680 1475b921609c7a8e73bf27f6929defec 608 Pfam PF00270 DEAD/DEAH box helicase 29 186 3.6E-19 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MC49_RS03680 1475b921609c7a8e73bf27f6929defec 608 Pfam PF16124 RecQ zinc-binding 343 404 2.8E-15 T 29-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain MC49_RS03680 1475b921609c7a8e73bf27f6929defec 608 SMART SM00487 22 218 8.6E-27 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MC49_RS03680 1475b921609c7a8e73bf27f6929defec 608 Gene3D G3DSA:3.40.50.300 210 403 5.5E-49 T 29-03-2018 MC49_RS03680 1475b921609c7a8e73bf27f6929defec 608 Pfam PF00271 Helicase conserved C-terminal domain 232 330 2.5E-18 T 29-03-2018 IPR001650 Helicase, C-terminal MC49_RS03680 1475b921609c7a8e73bf27f6929defec 608 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 16 464 2.6E-192 T 29-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 MC49_RS03680 1475b921609c7a8e73bf27f6929defec 608 SMART SM00341 529 608 6.7E-22 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 MC49_RS03680 1475b921609c7a8e73bf27f6929defec 608 Gene3D G3DSA:1.10.150.80 532 604 2.3E-25 T 29-03-2018 MC49_RS03680 1475b921609c7a8e73bf27f6929defec 608 SUPERFAMILY SSF52540 16 199 7.5E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS03680 1475b921609c7a8e73bf27f6929defec 608 Pfam PF00570 HRDC domain 533 599 9.3E-23 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 MC49_RS03680 1475b921609c7a8e73bf27f6929defec 608 Pfam PF09382 RQC domain 406 516 3.2E-40 T 29-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 MC49_RS03680 1475b921609c7a8e73bf27f6929defec 608 Gene3D G3DSA:3.40.50.300 2 208 3.4E-36 T 29-03-2018 MC49_RS03680 1475b921609c7a8e73bf27f6929defec 608 SMART SM00490 250 331 4.6E-28 T 29-03-2018 IPR001650 Helicase, C-terminal MC49_RS03680 1475b921609c7a8e73bf27f6929defec 608 Gene3D G3DSA:1.10.10.10 404 527 6.2E-38 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS03680 1475b921609c7a8e73bf27f6929defec 608 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 15 602 4.7E-262 T 29-03-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 MC49_RS16880 585447d414fa005a691d792d5af1d88d 190 SUPERFAMILY SSF53474 3 183 2.27E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS16880 585447d414fa005a691d792d5af1d88d 190 Gene3D G3DSA:3.40.50.1820 2 188 4.0E-17 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS16880 585447d414fa005a691d792d5af1d88d 190 Pfam PF06821 Serine hydrolase 6 183 5.4E-26 T 29-03-2018 IPR010662 Putative hydrolase RBBP9/YdeN GO:0016787 MC49_RS17675 429eaa3c5684681b4b1f248b0f774610 342 Pfam PF03592 Terminase small subunit 101 305 3.7E-25 T 29-03-2018 IPR005335 Terminase small subunit GO:0006323 MC49_RS12925 cd3cc1b8c66746f660c04867730d7ea7 215 Pfam PF00717 Peptidase S24-like 122 189 3.5E-13 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MC49_RS12925 cd3cc1b8c66746f660c04867730d7ea7 215 Gene3D G3DSA:2.10.109.10 87 206 3.6E-15 T 29-03-2018 MC49_RS12925 cd3cc1b8c66746f660c04867730d7ea7 215 SMART SM00530 6 61 3.1E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS12925 cd3cc1b8c66746f660c04867730d7ea7 215 Pfam PF01381 Helix-turn-helix 7 61 1.8E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS12925 cd3cc1b8c66746f660c04867730d7ea7 215 Gene3D G3DSA:1.10.260.40 1 76 1.9E-16 T 29-03-2018 MC49_RS12925 cd3cc1b8c66746f660c04867730d7ea7 215 SUPERFAMILY SSF47413 1 65 7.04E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS12925 cd3cc1b8c66746f660c04867730d7ea7 215 SUPERFAMILY SSF51306 115 205 4.45E-20 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MC49_RS04000 0154687540912767485c6c791aa565cd 314 Gene3D G3DSA:3.40.50.170 2 209 6.3E-69 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MC49_RS04000 0154687540912767485c6c791aa565cd 314 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 5 312 1.2E-110 T 29-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 MC49_RS04000 0154687540912767485c6c791aa565cd 314 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 136 159 - T 29-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MC49_RS04000 0154687540912767485c6c791aa565cd 314 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 5 307 36.464 T 29-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 MC49_RS04000 0154687540912767485c6c791aa565cd 314 Pfam PF00551 Formyl transferase 6 183 6.0E-51 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MC49_RS04000 0154687540912767485c6c791aa565cd 314 Gene3D G3DSA:3.10.25.10 210 312 3.7E-32 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MC49_RS04000 0154687540912767485c6c791aa565cd 314 Pfam PF02911 Formyl transferase, C-terminal domain 207 304 9.1E-32 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MC49_RS04000 0154687540912767485c6c791aa565cd 314 SUPERFAMILY SSF50486 208 309 1.18E-35 T 29-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 MC49_RS04000 0154687540912767485c6c791aa565cd 314 SUPERFAMILY SSF53328 5 207 9.68E-68 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MC49_RS10525 23f53cc530aef20b9a79db7b7324b025 261 SUPERFAMILY SSF50331 124 257 1.7E-19 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal MC49_RS10525 23f53cc530aef20b9a79db7b7324b025 261 PIRSF PIRSF005763 1 261 9.8E-96 T 29-03-2018 IPR016462 Molybdate-dependent transcriptional regulator ModE GO:0006355|GO:0015689|GO:0030151 MC49_RS10525 23f53cc530aef20b9a79db7b7324b025 261 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 18 81 2.2E-12 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS10525 23f53cc530aef20b9a79db7b7324b025 261 TIGRFAM TIGR00637 ModE_repress: ModE molybdate transport repressor domain 14 110 8.7E-37 T 29-03-2018 IPR003725 Molybdenum-binding protein ModE, N-terminal MC49_RS10525 23f53cc530aef20b9a79db7b7324b025 261 SUPERFAMILY SSF46785 3 101 5.12E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS10525 23f53cc530aef20b9a79db7b7324b025 261 Gene3D G3DSA:1.10.10.10 1 105 1.1E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS10525 23f53cc530aef20b9a79db7b7324b025 261 Gene3D G3DSA:2.40.50.100 181 251 1.9E-16 T 29-03-2018 MC49_RS10525 23f53cc530aef20b9a79db7b7324b025 261 Gene3D G3DSA:2.40.50.100 106 180 7.7E-16 T 29-03-2018 MC49_RS10525 23f53cc530aef20b9a79db7b7324b025 261 Pfam PF03459 TOBE domain 197 257 2.3E-7 T 29-03-2018 IPR005116 Transport-associated OB, type 1 MC49_RS10525 23f53cc530aef20b9a79db7b7324b025 261 Pfam PF03459 TOBE domain 122 186 1.7E-11 T 29-03-2018 IPR005116 Transport-associated OB, type 1 MC49_RS10525 23f53cc530aef20b9a79db7b7324b025 261 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 120 188 2.5E-23 T 29-03-2018 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 MC49_RS12060 06616aa7acce7cf38a08ee6f256ded1b 446 SMART SM00448 7 118 6.9E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS12060 06616aa7acce7cf38a08ee6f256ded1b 446 Pfam PF00158 Sigma-54 interaction domain 139 304 5.3E-72 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MC49_RS12060 06616aa7acce7cf38a08ee6f256ded1b 446 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 162 175 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MC49_RS12060 06616aa7acce7cf38a08ee6f256ded1b 446 SMART SM00382 158 301 3.1E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS12060 06616aa7acce7cf38a08ee6f256ded1b 446 Gene3D G3DSA:1.10.8.60 311 384 2.6E-21 T 29-03-2018 MC49_RS12060 06616aa7acce7cf38a08ee6f256ded1b 446 SUPERFAMILY SSF52172 6 182 2.42E-41 T 29-03-2018 IPR011006 CheY-like superfamily MC49_RS12060 06616aa7acce7cf38a08ee6f256ded1b 446 SUPERFAMILY SSF46689 389 439 1.52E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS12060 06616aa7acce7cf38a08ee6f256ded1b 446 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 351 360 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site MC49_RS12060 06616aa7acce7cf38a08ee6f256ded1b 446 Pfam PF00072 Response regulator receiver domain 10 118 1.5E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS12060 06616aa7acce7cf38a08ee6f256ded1b 446 Gene3D G3DSA:3.40.50.300 148 310 9.2E-25 T 29-03-2018 MC49_RS12060 06616aa7acce7cf38a08ee6f256ded1b 446 Gene3D G3DSA:1.10.10.60 385 441 1.4E-8 T 29-03-2018 MC49_RS12060 06616aa7acce7cf38a08ee6f256ded1b 446 SUPERFAMILY SSF52540 138 380 1.38E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS12060 06616aa7acce7cf38a08ee6f256ded1b 446 Gene3D G3DSA:3.40.50.2300 1 147 2.4E-35 T 29-03-2018 MC49_RS02385 fb9731cc072ecad435527495fe0c7052 167 SUPERFAMILY SSF49401 28 166 1.64E-31 T 29-03-2018 IPR008966 Adhesion domain MC49_RS02385 fb9731cc072ecad435527495fe0c7052 167 Gene3D G3DSA:2.60.40.1090 17 167 3.9E-27 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS02385 fb9731cc072ecad435527495fe0c7052 167 Pfam PF00419 Fimbrial protein 21 166 7.6E-16 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS06635 e674cffea63933d0d6fbc7583f70926a 288 Pfam PF01040 UbiA prenyltransferase family 28 271 1.3E-66 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 MC49_RS06635 e674cffea63933d0d6fbc7583f70926a 288 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 67 89 - T 29-03-2018 IPR030470 UbiA prenyltransferase conserved site MC49_RS06635 e674cffea63933d0d6fbc7583f70926a 288 TIGRFAM TIGR01474 ubiA_proteo: 4-hydroxybenzoate polyprenyl transferase 10 288 4.7E-114 T 29-03-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 MC49_RS06635 e674cffea63933d0d6fbc7583f70926a 288 Hamap MF_01635 4-hydroxybenzoate octaprenyltransferase [ubiA]. 5 288 30.075 T 29-03-2018 IPR031103 4-hydroxybenzoate octaprenyltransferase GO:0004659|GO:0006744|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 MC49_RS02320 3cb2c626ff4b9964066a9f5bfc258c75 264 SMART SM00382 36 227 2.1E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS02320 3cb2c626ff4b9964066a9f5bfc258c75 264 SUPERFAMILY SSF52540 8 251 2.56E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS02320 3cb2c626ff4b9964066a9f5bfc258c75 264 Gene3D G3DSA:3.40.50.300 4 257 1.8E-57 T 29-03-2018 MC49_RS02320 3cb2c626ff4b9964066a9f5bfc258c75 264 Pfam PF00005 ABC transporter 28 178 5.0E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS02320 3cb2c626ff4b9964066a9f5bfc258c75 264 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS02320 3cb2c626ff4b9964066a9f5bfc258c75 264 TIGRFAM TIGR02770 nickel_nikD: nickel import ATP-binding protein NikD 26 255 8.2E-99 T 29-03-2018 IPR014138 Nickel import ATP-binding protein NikD GO:0005886|GO:0015413|GO:0015675|GO:0016151 MC49_RS08290 979d7188a2be48bb8167dcde23709570 159 Pfam PF13673 Acetyltransferase (GNAT) domain 55 140 1.1E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MC49_RS08290 979d7188a2be48bb8167dcde23709570 159 SUPERFAMILY SSF55729 11 152 8.44E-21 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS08290 979d7188a2be48bb8167dcde23709570 159 Gene3D G3DSA:3.40.630.30 14 149 1.5E-18 T 29-03-2018 MC49_RS01630 a5fa93b3449793d6dda36bf91a4dad53 182 Gene3D G3DSA:1.10.60.30 112 182 2.1E-27 T 29-03-2018 MC49_RS01630 a5fa93b3449793d6dda36bf91a4dad53 182 PIRSF PIRSF016183 10 182 1.3E-66 T 29-03-2018 IPR006839 Ribosome-associated, YjgA MC49_RS01630 a5fa93b3449793d6dda36bf91a4dad53 182 SUPERFAMILY SSF158710 38 179 3.14E-51 T 29-03-2018 IPR023153 PSPTO4464-like domain MC49_RS01630 a5fa93b3449793d6dda36bf91a4dad53 182 Gene3D G3DSA:1.10.60.30 38 106 2.0E-26 T 29-03-2018 MC49_RS01630 a5fa93b3449793d6dda36bf91a4dad53 182 Hamap MF_00765 UPF0307 protein YjgA [yjgA]. 16 180 22.821 T 29-03-2018 IPR006839 Ribosome-associated, YjgA MC49_RS01630 a5fa93b3449793d6dda36bf91a4dad53 182 Pfam PF04751 Protein of unknown function (DUF615) 26 176 1.7E-55 T 29-03-2018 IPR006839 Ribosome-associated, YjgA MC49_RS00860 dbeb80e63e461b1dcca54dfd6b980e1a 156 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 8 154 31.424 T 29-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MC49_RS00860 dbeb80e63e461b1dcca54dfd6b980e1a 156 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 14 150 2.5E-58 T 29-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MC49_RS00860 dbeb80e63e461b1dcca54dfd6b980e1a 156 Gene3D G3DSA:3.40.50.960 1 155 3.1E-64 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MC49_RS00860 dbeb80e63e461b1dcca54dfd6b980e1a 156 SUPERFAMILY SSF52121 3 154 1.44E-60 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MC49_RS00860 dbeb80e63e461b1dcca54dfd6b980e1a 156 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 13 151 1.6E-56 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MC49_RS00810 da63ba93b5627cfbfa34f72468c42ad1 163 Gene3D G3DSA:3.30.70.990 10 97 1.2E-28 T 29-03-2018 IPR035570 UPF0234 N-terminal domain MC49_RS00810 da63ba93b5627cfbfa34f72468c42ad1 163 SUPERFAMILY SSF89963 92 163 6.28E-29 T 29-03-2018 IPR007551 Protein of unknown function DUF520 MC49_RS00810 da63ba93b5627cfbfa34f72468c42ad1 163 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 1 163 29.057 T 29-03-2018 IPR007551 Protein of unknown function DUF520 MC49_RS00810 da63ba93b5627cfbfa34f72468c42ad1 163 Pfam PF04461 Protein of unknown function (DUF520) 2 162 1.4E-64 T 29-03-2018 IPR007551 Protein of unknown function DUF520 MC49_RS00810 da63ba93b5627cfbfa34f72468c42ad1 163 SUPERFAMILY SSF89963 2 89 1.94E-29 T 29-03-2018 IPR007551 Protein of unknown function DUF520 MC49_RS00810 da63ba93b5627cfbfa34f72468c42ad1 163 Gene3D G3DSA:3.30.70.860 98 162 5.5E-34 T 29-03-2018 IPR035571 UPF0234/UPF0381 domain MC49_RS01525 e30ca761800c3d82552a752fd5da523e 96 Gene3D G3DSA:3.30.750.24 4 95 3.3E-5 T 29-03-2018 IPR002645 STAS domain MC49_RS01525 e30ca761800c3d82552a752fd5da523e 96 Pfam PF13466 STAS domain 14 88 2.2E-14 T 29-03-2018 IPR002645 STAS domain MC49_RS01525 e30ca761800c3d82552a752fd5da523e 96 SUPERFAMILY SSF52091 1 89 1.77E-11 T 29-03-2018 IPR002645 STAS domain MC49_RS10870 428493435651efbf79eed7f2bd63cfef 203 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 115 198 3.8E-30 T 29-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 MC49_RS10870 428493435651efbf79eed7f2bd63cfef 203 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 56 105 4.0E-20 T 29-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 MC49_RS10870 428493435651efbf79eed7f2bd63cfef 203 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 33 105 5.9E-30 T 29-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 MC49_RS10870 428493435651efbf79eed7f2bd63cfef 203 SUPERFAMILY SSF101386 114 202 3.18E-24 T 29-03-2018 MC49_RS10870 428493435651efbf79eed7f2bd63cfef 203 SUPERFAMILY SSF141734 6 118 1.31E-43 T 29-03-2018 MC49_RS10870 428493435651efbf79eed7f2bd63cfef 203 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 8 203 36.344 T 29-03-2018 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 MC49_RS10870 428493435651efbf79eed7f2bd63cfef 203 Gene3D G3DSA:1.10.287.1080 111 203 3.5E-21 T 29-03-2018 MC49_RS10870 428493435651efbf79eed7f2bd63cfef 203 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 116 201 3.7E-17 T 29-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 MC49_RS10870 428493435651efbf79eed7f2bd63cfef 203 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 112 198 18.648 T 29-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 MC49_RS01845 d2c8c8f1a4119d7e80324a22df83a03d 284 PRINTS PR00046 Major sigma-70 factor signature 77 90 2.6E-19 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS01845 d2c8c8f1a4119d7e80324a22df83a03d 284 PRINTS PR00046 Major sigma-70 factor signature 252 267 2.6E-19 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS01845 d2c8c8f1a4119d7e80324a22df83a03d 284 PRINTS PR00046 Major sigma-70 factor signature 232 244 2.6E-19 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS01845 d2c8c8f1a4119d7e80324a22df83a03d 284 PRINTS PR00046 Major sigma-70 factor signature 267 278 2.6E-19 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS01845 d2c8c8f1a4119d7e80324a22df83a03d 284 Pfam PF00140 Sigma-70 factor, region 1.2 15 40 2.7E-7 T 29-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS01845 d2c8c8f1a4119d7e80324a22df83a03d 284 SUPERFAMILY SSF88946 12 122 6.93E-41 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS01845 d2c8c8f1a4119d7e80324a22df83a03d 284 Gene3D G3DSA:1.10.601.10 12 122 1.0E-34 T 29-03-2018 MC49_RS01845 d2c8c8f1a4119d7e80324a22df83a03d 284 SUPERFAMILY SSF88659 199 283 4.3E-20 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS01845 d2c8c8f1a4119d7e80324a22df83a03d 284 Pfam PF04542 Sigma-70 region 2 53 122 3.0E-16 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS01845 d2c8c8f1a4119d7e80324a22df83a03d 284 PIRSF PIRSF000770 10 284 1.4E-33 T 29-03-2018 MC49_RS01845 d2c8c8f1a4119d7e80324a22df83a03d 284 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 14 283 5.0E-130 T 29-03-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 MC49_RS01845 d2c8c8f1a4119d7e80324a22df83a03d 284 Gene3D G3DSA:1.10.10.10 222 284 3.8E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS01845 d2c8c8f1a4119d7e80324a22df83a03d 284 Gene3D G3DSA:3.30.56.50 154 171 0.059 T 29-03-2018 MC49_RS01845 d2c8c8f1a4119d7e80324a22df83a03d 284 Pfam PF04545 Sigma-70, region 4 228 280 3.1E-17 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS01845 d2c8c8f1a4119d7e80324a22df83a03d 284 Hamap MF_00961 RNA polymerase sigma factor RpoH [rpoH]. 1 284 54.166 T 29-03-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 MC49_RS01845 d2c8c8f1a4119d7e80324a22df83a03d 284 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 77 90 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS01845 d2c8c8f1a4119d7e80324a22df83a03d 284 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 252 278 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS01845 d2c8c8f1a4119d7e80324a22df83a03d 284 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 48 281 2.2E-37 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS11860 86a6b7da1f23c9f76fc663fe2ec372fa 86 Gene3D G3DSA:3.30.70.20 2 83 2.2E-16 T 29-03-2018 MC49_RS11860 86a6b7da1f23c9f76fc663fe2ec372fa 86 SUPERFAMILY SSF54862 5 76 2.56E-18 T 29-03-2018 MC49_RS11860 86a6b7da1f23c9f76fc663fe2ec372fa 86 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MC49_RS11860 86a6b7da1f23c9f76fc663fe2ec372fa 86 Pfam PF00037 4Fe-4S binding domain 5 25 1.4E-6 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MC49_RS06045 b553421e29d22097ab4ac29151f768ea 410 Pfam PF03616 Sodium/glutamate symporter 2 372 9.7E-157 T 29-03-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 MC49_RS06045 b553421e29d22097ab4ac29151f768ea 410 Hamap MF_02062 Sodium/glutamate symporter [gltS]. 2 403 24.849 T 29-03-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 MC49_RS06045 b553421e29d22097ab4ac29151f768ea 410 TIGRFAM TIGR00210 gltS: sodium/glutamate symporter 2 403 9.9E-179 T 29-03-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 MC49_RS05060 b629630e8d78b0d0cb35ed2278a6031d 228 SMART SM00895 106 227 2.6E-18 T 29-03-2018 IPR011711 GntR, C-terminal MC49_RS05060 b629630e8d78b0d0cb35ed2278a6031d 228 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 1.8E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MC49_RS05060 b629630e8d78b0d0cb35ed2278a6031d 228 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 1.8E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MC49_RS05060 b629630e8d78b0d0cb35ed2278a6031d 228 Gene3D G3DSA:1.10.10.10 1 79 1.0E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS05060 b629630e8d78b0d0cb35ed2278a6031d 228 SUPERFAMILY SSF48008 108 225 2.46E-19 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MC49_RS05060 b629630e8d78b0d0cb35ed2278a6031d 228 SUPERFAMILY SSF46785 10 80 2.28E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS05060 b629630e8d78b0d0cb35ed2278a6031d 228 SMART SM00345 18 77 6.0E-20 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MC49_RS05060 b629630e8d78b0d0cb35ed2278a6031d 228 Gene3D G3DSA:1.20.120.530 101 228 2.6E-20 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MC49_RS05060 b629630e8d78b0d0cb35ed2278a6031d 228 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 77 1.0E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MC49_RS05060 b629630e8d78b0d0cb35ed2278a6031d 228 Pfam PF07729 FCD domain 108 224 5.6E-22 T 29-03-2018 IPR011711 GntR, C-terminal MC49_RS14850 4e00bedff74c8c812a5bd2c1bbe56bfb 140 Pfam PF13411 MerR HTH family regulatory protein 6 71 3.1E-14 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MC49_RS14850 4e00bedff74c8c812a5bd2c1bbe56bfb 140 SUPERFAMILY SSF46955 3 106 1.47E-23 T 29-03-2018 IPR009061 Putative DNA-binding domain MC49_RS14850 4e00bedff74c8c812a5bd2c1bbe56bfb 140 ProSitePatterns PS00552 MerR-type HTH domain signature. 7 29 - T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MC49_RS14850 4e00bedff74c8c812a5bd2c1bbe56bfb 140 SMART SM00422 4 72 5.1E-16 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MC49_RS14850 4e00bedff74c8c812a5bd2c1bbe56bfb 140 Gene3D G3DSA:1.10.1660.10 1 59 4.1E-18 T 29-03-2018 MC49_RS14850 4e00bedff74c8c812a5bd2c1bbe56bfb 140 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 5 16 1.8E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MC49_RS14850 4e00bedff74c8c812a5bd2c1bbe56bfb 140 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 16 29 1.8E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MC49_RS14850 4e00bedff74c8c812a5bd2c1bbe56bfb 140 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 1.8E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MC49_RS14850 4e00bedff74c8c812a5bd2c1bbe56bfb 140 Gene3D G3DSA:1.10.1660.10 60 137 1.8E-8 T 29-03-2018 MC49_RS06620 cb4b402501a01f4e1c1451a83174bc94 455 Pfam PF00696 Amino acid kinase family 12 284 2.5E-44 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MC49_RS06620 cb4b402501a01f4e1c1451a83174bc94 455 Gene3D G3DSA:3.30.70.260 376 455 5.5E-15 T 29-03-2018 MC49_RS06620 cb4b402501a01f4e1c1451a83174bc94 455 PIRSF PIRSF000726 9 455 1.5E-134 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 MC49_RS06620 cb4b402501a01f4e1c1451a83174bc94 455 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 12 454 1.3E-128 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 MC49_RS06620 cb4b402501a01f4e1c1451a83174bc94 455 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 11 455 9.4E-122 T 29-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 MC49_RS06620 cb4b402501a01f4e1c1451a83174bc94 455 SUPERFAMILY SSF55021 384 454 1.49E-13 T 29-03-2018 MC49_RS06620 cb4b402501a01f4e1c1451a83174bc94 455 Gene3D G3DSA:3.40.1160.10 9 291 3.5E-61 T 29-03-2018 MC49_RS06620 cb4b402501a01f4e1c1451a83174bc94 455 ProSitePatterns PS00324 Aspartokinase signature. 13 21 - T 29-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 MC49_RS06620 cb4b402501a01f4e1c1451a83174bc94 455 SUPERFAMILY SSF53633 12 299 1.31E-72 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MC49_RS06620 cb4b402501a01f4e1c1451a83174bc94 455 SUPERFAMILY SSF55021 304 400 3.02E-16 T 29-03-2018 MC49_RS06620 cb4b402501a01f4e1c1451a83174bc94 455 Gene3D G3DSA:3.30.70.260 292 366 8.1E-18 T 29-03-2018 MC49_RS06420 a2abc284acaf14d4b11ec7a4f25ad383 121 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 121 25.521 T 29-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS06420 a2abc284acaf14d4b11ec7a4f25ad383 121 Gene3D G3DSA:3.30.1390.10 51 121 5.6E-31 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like MC49_RS06420 a2abc284acaf14d4b11ec7a4f25ad383 121 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 4 50 3.3E-17 T 29-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS06420 a2abc284acaf14d4b11ec7a4f25ad383 121 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 121 2.4E-48 T 29-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS06420 a2abc284acaf14d4b11ec7a4f25ad383 121 SUPERFAMILY SSF48300 3 57 2.62E-16 T 29-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS06420 a2abc284acaf14d4b11ec7a4f25ad383 121 SUPERFAMILY SSF54736 50 121 3.84E-25 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like MC49_RS06420 a2abc284acaf14d4b11ec7a4f25ad383 121 Gene3D G3DSA:1.20.5.710 2 50 1.1E-17 T 29-03-2018 MC49_RS06420 a2abc284acaf14d4b11ec7a4f25ad383 121 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 55 121 4.2E-31 T 29-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS06420 a2abc284acaf14d4b11ec7a4f25ad383 121 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 56 121 7.0E-27 T 29-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS18655 3406d0dd04b9d309c99a53a64e4ed733 397 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 342 366 - T 29-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 MC49_RS18655 3406d0dd04b9d309c99a53a64e4ed733 397 Pfam PF01098 Cell cycle protein 30 384 2.2E-120 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 MC49_RS18655 3406d0dd04b9d309c99a53a64e4ed733 397 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 28 383 1.6E-130 T 29-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 MC49_RS18655 3406d0dd04b9d309c99a53a64e4ed733 397 Hamap MF_00913 Putative lipid II flippase FtsW [ftsW]. 26 393 41.416 T 29-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 MC49_RS00525 d09e766fc48a2870a06ee3d0f8cfd749 1546 Pfam PF13332 Haemagluttinin repeat 546 616 0.004 T 29-03-2018 IPR025157 Hemagglutinin repeat MC49_RS00525 d09e766fc48a2870a06ee3d0f8cfd749 1546 Pfam PF13332 Haemagluttinin repeat 1198 1360 1.3E-25 T 29-03-2018 IPR025157 Hemagglutinin repeat MC49_RS00525 d09e766fc48a2870a06ee3d0f8cfd749 1546 Pfam PF13332 Haemagluttinin repeat 630 782 3.9E-14 T 29-03-2018 IPR025157 Hemagglutinin repeat MC49_RS00525 d09e766fc48a2870a06ee3d0f8cfd749 1546 Pfam PF13332 Haemagluttinin repeat 393 532 4.6E-11 T 29-03-2018 IPR025157 Hemagglutinin repeat MC49_RS00525 d09e766fc48a2870a06ee3d0f8cfd749 1546 Pfam PF13332 Haemagluttinin repeat 926 1084 6.0E-14 T 29-03-2018 IPR025157 Hemagglutinin repeat MC49_RS00525 d09e766fc48a2870a06ee3d0f8cfd749 1546 SMART SM00912 46 166 2.5E-40 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal MC49_RS00525 d09e766fc48a2870a06ee3d0f8cfd749 1546 Pfam PF05594 Haemagluttinin repeat 213 307 7.2E-7 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat MC49_RS00525 d09e766fc48a2870a06ee3d0f8cfd749 1546 Pfam PF05594 Haemagluttinin repeat 331 384 110.0 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat MC49_RS00525 d09e766fc48a2870a06ee3d0f8cfd749 1546 Pfam PF05594 Haemagluttinin repeat 825 857 140.0 T 29-03-2018 IPR008619 Filamentous haemagglutinin repeat MC49_RS00525 d09e766fc48a2870a06ee3d0f8cfd749 1546 Gene3D G3DSA:2.160.20.10 38 313 5.6E-46 T 29-03-2018 IPR012334 Pectin lyase fold MC49_RS00525 d09e766fc48a2870a06ee3d0f8cfd749 1546 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 64 154 8.1E-17 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal MC49_RS00525 d09e766fc48a2870a06ee3d0f8cfd749 1546 Pfam PF05860 haemagglutination activity domain 34 165 4.1E-28 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal MC49_RS00525 d09e766fc48a2870a06ee3d0f8cfd749 1546 SUPERFAMILY SSF51126 47 302 9.42E-53 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor MC49_RS00525 d09e766fc48a2870a06ee3d0f8cfd749 1546 Gene3D G3DSA:2.160.20.10 325 484 0.22 T 29-03-2018 IPR012334 Pectin lyase fold MC49_RS00525 d09e766fc48a2870a06ee3d0f8cfd749 1546 Gene3D G3DSA:2.160.20.10 565 794 0.0012 T 29-03-2018 IPR012334 Pectin lyase fold MC49_RS02040 15aadbbce8eed9ca3a690471c1909e5b 526 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 73 98 2.2E-9 T 29-03-2018 MC49_RS02040 15aadbbce8eed9ca3a690471c1909e5b 526 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 228 249 2.2E-9 T 29-03-2018 MC49_RS02040 15aadbbce8eed9ca3a690471c1909e5b 526 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 321 333 2.2E-9 T 29-03-2018 MC49_RS02040 15aadbbce8eed9ca3a690471c1909e5b 526 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 70 102 3.2E-6 T 29-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS02040 15aadbbce8eed9ca3a690471c1909e5b 526 Pfam PF00361 Proton-conducting membrane transporter 132 426 1.8E-56 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS04515 d1bc50e951a51e99687b510d3394c335 221 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 3 205 3.8E-91 T 29-03-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 MC49_RS04515 d1bc50e951a51e99687b510d3394c335 221 SUPERFAMILY SSF100950 2 213 1.97E-67 T 29-03-2018 MC49_RS04515 d1bc50e951a51e99687b510d3394c335 221 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 43 51 - T 29-03-2018 IPR004164 Coenzyme A transferase active site GO:0008152|GO:0008410 Reactome: R-HSA-77108 MC49_RS04515 d1bc50e951a51e99687b510d3394c335 221 Gene3D G3DSA:3.40.1080.10 2 210 4.1E-63 T 29-03-2018 MC49_RS04515 d1bc50e951a51e99687b510d3394c335 221 SMART SM00882 5 198 6.4E-63 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 MC49_RS04515 d1bc50e951a51e99687b510d3394c335 221 Pfam PF01144 Coenzyme A transferase 6 195 8.4E-36 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 MC49_RS00570 31ca33229b841997f0670f8ad76d0a1f 555 Gene3D G3DSA:3.60.21.10 26 364 6.6E-86 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like MC49_RS00570 31ca33229b841997f0670f8ad76d0a1f 555 Pfam PF02872 5'-nucleotidase, C-terminal domain 365 510 5.7E-32 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MC49_RS00570 31ca33229b841997f0670f8ad76d0a1f 555 SUPERFAMILY SSF56300 27 363 1.05E-98 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like MC49_RS00570 31ca33229b841997f0670f8ad76d0a1f 555 PRINTS PR01607 Apyrase family signature 207 224 1.5E-58 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MC49_RS00570 31ca33229b841997f0670f8ad76d0a1f 555 PRINTS PR01607 Apyrase family signature 487 506 1.5E-58 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MC49_RS00570 31ca33229b841997f0670f8ad76d0a1f 555 PRINTS PR01607 Apyrase family signature 32 50 1.5E-58 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MC49_RS00570 31ca33229b841997f0670f8ad76d0a1f 555 PRINTS PR01607 Apyrase family signature 238 261 1.5E-58 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MC49_RS00570 31ca33229b841997f0670f8ad76d0a1f 555 PRINTS PR01607 Apyrase family signature 419 442 1.5E-58 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MC49_RS00570 31ca33229b841997f0670f8ad76d0a1f 555 PRINTS PR01607 Apyrase family signature 285 305 1.5E-58 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MC49_RS00570 31ca33229b841997f0670f8ad76d0a1f 555 ProSitePatterns PS00785 5'-nucleotidase signature 1. 34 46 - T 29-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MC49_RS00570 31ca33229b841997f0670f8ad76d0a1f 555 Gene3D G3DSA:3.90.780.10 365 552 1.7E-45 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MC49_RS00570 31ca33229b841997f0670f8ad76d0a1f 555 ProSitePatterns PS00786 5'-nucleotidase signature 2. 109 120 - T 29-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MC49_RS00570 31ca33229b841997f0670f8ad76d0a1f 555 Pfam PF00149 Calcineurin-like phosphoesterase 35 254 1.7E-17 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MC49_RS00570 31ca33229b841997f0670f8ad76d0a1f 555 SUPERFAMILY SSF55816 365 544 3.01E-50 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 MC49_RS06210 61d0f1fb4c4cc10f451017b607c84adb 371 TIGRFAM TIGR02665 molyb_mobA: molybdenum cofactor guanylyltransferase 12 191 1.1E-62 T 29-03-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 MC49_RS06210 61d0f1fb4c4cc10f451017b607c84adb 371 Gene3D G3DSA:3.40.50.300 204 371 2.3E-28 T 29-03-2018 MC49_RS06210 61d0f1fb4c4cc10f451017b607c84adb 371 SUPERFAMILY SSF52540 203 368 3.79E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS06210 61d0f1fb4c4cc10f451017b607c84adb 371 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 207 340 7.7E-46 T 29-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 MC49_RS06210 61d0f1fb4c4cc10f451017b607c84adb 371 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 207 366 6.4E-44 T 29-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 MC49_RS06210 61d0f1fb4c4cc10f451017b607c84adb 371 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 9 194 26.9 T 29-03-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 MC49_RS06210 61d0f1fb4c4cc10f451017b607c84adb 371 SUPERFAMILY SSF53448 9 189 4.98E-30 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MC49_RS06210 61d0f1fb4c4cc10f451017b607c84adb 371 Gene3D G3DSA:3.90.550.10 6 200 6.2E-26 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MC49_RS06210 61d0f1fb4c4cc10f451017b607c84adb 371 Pfam PF12804 MobA-like NTP transferase domain 13 162 6.8E-30 T 29-03-2018 IPR025877 MobA-like NTP transferase MC49_RS12530 b97aca898ed19c0c071844d65bb5fa0c 403 Pfam PF07559 Flagellar basal body protein FlaE 174 284 1.6E-18 T 29-03-2018 IPR011491 Flagellar hook protein FlgE MC49_RS12530 b97aca898ed19c0c071844d65bb5fa0c 403 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 9 29 - T 29-03-2018 IPR019776 Flagellar basal body rod protein, conserved site MC49_RS12530 b97aca898ed19c0c071844d65bb5fa0c 403 Pfam PF00460 Flagella basal body rod protein 4 33 8.3E-8 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 MC49_RS12530 b97aca898ed19c0c071844d65bb5fa0c 403 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 324 402 2.5E-19 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain MC49_RS12530 b97aca898ed19c0c071844d65bb5fa0c 403 SUPERFAMILY SSF117143 73 364 3.92E-77 T 29-03-2018 MC49_RS12530 b97aca898ed19c0c071844d65bb5fa0c 403 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 1 385 9.9E-94 T 29-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G MC49_RS12530 b97aca898ed19c0c071844d65bb5fa0c 403 Gene3D G3DSA:2.60.98.20 149 285 5.9E-34 T 29-03-2018 IPR011491 Flagellar hook protein FlgE MC49_RS17865 552b4b4e36fc1fbd1f88f5068812accf 219 Pfam PF00072 Response regulator receiver domain 4 116 9.6E-16 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS17865 552b4b4e36fc1fbd1f88f5068812accf 219 SMART SM00421 147 204 5.3E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS17865 552b4b4e36fc1fbd1f88f5068812accf 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS17865 552b4b4e36fc1fbd1f88f5068812accf 219 Gene3D G3DSA:1.10.10.10 126 214 4.3E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS17865 552b4b4e36fc1fbd1f88f5068812accf 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 204 9.2E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS17865 552b4b4e36fc1fbd1f88f5068812accf 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 2.1E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS17865 552b4b4e36fc1fbd1f88f5068812accf 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 2.1E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS17865 552b4b4e36fc1fbd1f88f5068812accf 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 2.1E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS17865 552b4b4e36fc1fbd1f88f5068812accf 219 SUPERFAMILY SSF52172 3 131 3.7E-21 T 29-03-2018 IPR011006 CheY-like superfamily MC49_RS17865 552b4b4e36fc1fbd1f88f5068812accf 219 Gene3D G3DSA:3.40.50.2300 1 125 8.7E-21 T 29-03-2018 MC49_RS17865 552b4b4e36fc1fbd1f88f5068812accf 219 SUPERFAMILY SSF46894 133 211 2.82E-19 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MC49_RS17865 552b4b4e36fc1fbd1f88f5068812accf 219 SMART SM00448 2 115 6.7E-11 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS03825 519c0e14848f49e14776247e5d22a578 376 Hamap MF_02028 UDP-N-acetylglucosamine 2-epimerase [wecB]. 16 374 68.627 T 29-03-2018 IPR032892 UDP-N-acetylglucosamine 2-epimerase WecB GO:0008761|GO:0009246 KEGG: 00520+5.1.3.14|MetaCyc: PWY-7335|MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819 MC49_RS03825 519c0e14848f49e14776247e5d22a578 376 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 1 372 1.3E-170 T 29-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 MC49_RS03825 519c0e14848f49e14776247e5d22a578 376 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 22 370 6.4E-125 T 29-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 MC49_RS03825 519c0e14848f49e14776247e5d22a578 376 Gene3D G3DSA:3.40.50.2000 1 205 8.8E-80 T 29-03-2018 MC49_RS03825 519c0e14848f49e14776247e5d22a578 376 SUPERFAMILY SSF53756 2 371 5.89E-140 T 29-03-2018 MC49_RS03825 519c0e14848f49e14776247e5d22a578 376 Gene3D G3DSA:3.40.50.2000 206 350 2.4E-47 T 29-03-2018 MC49_RS05175 945c7d84d497fb528ef509e4b9430cff 460 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 460 56.757 T 29-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 MC49_RS05175 945c7d84d497fb528ef509e4b9430cff 460 Gene3D G3DSA:1.10.1140.10 348 458 8.1E-46 T 29-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MC49_RS05175 945c7d84d497fb528ef509e4b9430cff 460 SUPERFAMILY SSF52540 77 348 7.69E-89 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS05175 945c7d84d497fb528ef509e4b9430cff 460 SMART SM00382 142 327 4.2E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS05175 945c7d84d497fb528ef509e4b9430cff 460 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 73 2.2E-20 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MC49_RS05175 945c7d84d497fb528ef509e4b9430cff 460 Gene3D G3DSA:3.40.50.300 76 347 2.2E-89 T 29-03-2018 MC49_RS05175 945c7d84d497fb528ef509e4b9430cff 460 SUPERFAMILY SSF50615 1 75 3.4E-25 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MC49_RS05175 945c7d84d497fb528ef509e4b9430cff 460 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 460 1.8E-262 T 29-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 MC49_RS05175 945c7d84d497fb528ef509e4b9430cff 460 SUPERFAMILY SSF47917 345 459 2.88E-55 T 29-03-2018 MC49_RS05175 945c7d84d497fb528ef509e4b9430cff 460 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 130 342 4.2E-63 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MC49_RS05175 945c7d84d497fb528ef509e4b9430cff 460 Gene3D G3DSA:2.40.10.170 1 75 7.7E-31 T 29-03-2018 MC49_RS05175 945c7d84d497fb528ef509e4b9430cff 460 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 333 342 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MC49_RS13795 070c5d1164872297e8855bb944f708ef 51 Pfam PF10617 Protein of unknown function (DUF2474) 12 49 1.7E-18 T 29-03-2018 IPR018895 Protein of unknown function DUF2474 MC49_RS09605 5fee7d040fcff012142da59a12b8df39 198 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 4 195 4.6E-64 T 29-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 MC49_RS09605 5fee7d040fcff012142da59a12b8df39 198 Pfam PF01725 Ham1 family 5 193 1.8E-55 T 29-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 MC49_RS09605 5fee7d040fcff012142da59a12b8df39 198 SUPERFAMILY SSF52972 2 196 1.6E-72 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MC49_RS09605 5fee7d040fcff012142da59a12b8df39 198 Gene3D G3DSA:3.90.950.10 1 198 1.2E-77 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MC49_RS09605 5fee7d040fcff012142da59a12b8df39 198 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 3 197 50.694 T 29-03-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 MC49_RS04375 30151c8637406c92d448cb111f780d51 161 Hamap MF_00105 Transcription elongation factor GreA [greA]. 3 155 29.398 T 29-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 MC49_RS04375 30151c8637406c92d448cb111f780d51 161 SUPERFAMILY SSF54534 81 157 2.62E-23 T 29-03-2018 MC49_RS04375 30151c8637406c92d448cb111f780d51 161 Gene3D G3DSA:3.10.50.30 77 161 2.3E-27 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 MC49_RS04375 30151c8637406c92d448cb111f780d51 161 SUPERFAMILY SSF46557 4 79 1.1E-26 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 MC49_RS04375 30151c8637406c92d448cb111f780d51 161 TIGRFAM TIGR01461 greB: transcription elongation factor GreB 4 157 1.6E-71 T 29-03-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 MC49_RS04375 30151c8637406c92d448cb111f780d51 161 Pfam PF03449 Transcription elongation factor, N-terminal 6 75 5.2E-26 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 MC49_RS04375 30151c8637406c92d448cb111f780d51 161 Gene3D G3DSA:1.10.287.180 4 76 6.7E-29 T 29-03-2018 MC49_RS04375 30151c8637406c92d448cb111f780d51 161 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 82 156 3.0E-27 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 MC49_RS04375 30151c8637406c92d448cb111f780d51 161 PIRSF PIRSF006092 1 158 5.0E-57 T 29-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 MC49_RS04375 30151c8637406c92d448cb111f780d51 161 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 120 136 - T 29-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 MC49_RS04375 30151c8637406c92d448cb111f780d51 161 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 18 49 - T 29-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 MC49_RS04375 30151c8637406c92d448cb111f780d51 161 Hamap MF_00930 Transcription elongation factor GreB [greB]. 2 157 53.164 T 29-03-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 MC49_RS08680 45195977f1f59a72eca1c5e7bf9ed793 438 Gene3D G3DSA:2.30.40.10 17 89 8.2E-13 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS08680 45195977f1f59a72eca1c5e7bf9ed793 438 Pfam PF01979 Amidohydrolase family 72 434 6.2E-78 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MC49_RS08680 45195977f1f59a72eca1c5e7bf9ed793 438 TIGRFAM TIGR02967 guan_deamin: guanine deaminase 32 431 5.5E-187 T 29-03-2018 IPR014311 Guanine deaminase GO:0006147|GO:0008270|GO:0008892 KEGG: 00230+3.5.4.3|MetaCyc: PWY-5497|MetaCyc: PWY-6606|MetaCyc: PWY-6608|MetaCyc: PWY-7442|Reactome: R-HSA-74259 MC49_RS08680 45195977f1f59a72eca1c5e7bf9ed793 438 SUPERFAMILY SSF51556 75 378 2.6E-105 T 29-03-2018 IPR032466 Metal-dependent hydrolase MC49_RS08680 45195977f1f59a72eca1c5e7bf9ed793 438 Gene3D G3DSA:3.20.20.140 90 377 1.9E-72 T 29-03-2018 MC49_RS08680 45195977f1f59a72eca1c5e7bf9ed793 438 SUPERFAMILY SSF51338 26 91 1.27E-9 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS15975 c124e125148b235d8db2a367157e13a0 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 64 6.7E-27 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MC49_RS15975 c124e125148b235d8db2a367157e13a0 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 18.203 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MC49_RS15975 c124e125148b235d8db2a367157e13a0 65 SUPERFAMILY SSF143034 2 64 6.54E-23 T 29-03-2018 MC49_RS15975 c124e125148b235d8db2a367157e13a0 65 Pfam PF01632 Ribosomal protein L35 2 60 3.0E-23 T 29-03-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS15975 c124e125148b235d8db2a367157e13a0 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 7.2E-23 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MC49_RS15975 c124e125148b235d8db2a367157e13a0 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 7.2E-23 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MC49_RS15975 c124e125148b235d8db2a367157e13a0 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 7.2E-23 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MC49_RS15975 c124e125148b235d8db2a367157e13a0 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 29-03-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS01865 e91dc67ba487bcafc7e0e5fca4630c94 202 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 3 190 1.5E-66 T 29-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 MC49_RS01865 e91dc67ba487bcafc7e0e5fca4630c94 202 Pfam PF03602 Conserved hypothetical protein 95 13 188 1.8E-61 T 29-03-2018 MC49_RS01865 e91dc67ba487bcafc7e0e5fca4630c94 202 SUPERFAMILY SSF53335 12 190 2.53E-53 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS01865 e91dc67ba487bcafc7e0e5fca4630c94 202 PIRSF PIRSF004553 12 192 1.5E-55 T 29-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 MC49_RS01865 e91dc67ba487bcafc7e0e5fca4630c94 202 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 125 131 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MC49_RS01865 e91dc67ba487bcafc7e0e5fca4630c94 202 Gene3D G3DSA:3.40.50.150 1 201 2.0E-37 T 29-03-2018 MC49_RS05395 72ee78d1842b2cd30351c51ae280554c 259 SUPERFAMILY SSF56925 110 258 1.88E-20 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MC49_RS05395 72ee78d1842b2cd30351c51ae280554c 259 Pfam PF01298 C-lobe and N-lobe beta barrels of Tf-binding protein B 138 258 2.2E-11 T 29-03-2018 IPR001677 Transferrin-binding protein, C-lobe/N-lobe beta barrel domain MC49_RS13050 3546ea332fb8e1faec055f56a586dcff 171 PIRSF PIRSF036893 1 169 1.6E-46 T 29-03-2018 IPR022271 Lipocalin, ApoD type MC49_RS13050 3546ea332fb8e1faec055f56a586dcff 171 Pfam PF08212 Lipocalin-like domain 32 167 3.3E-42 T 29-03-2018 IPR000566 Lipocalin/cytosolic fatty-acid binding domain MC49_RS13050 3546ea332fb8e1faec055f56a586dcff 171 PRINTS PR01171 Bacterial lipocalin signature 68 77 8.9E-37 T 29-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 MC49_RS13050 3546ea332fb8e1faec055f56a586dcff 171 PRINTS PR01171 Bacterial lipocalin signature 32 46 8.9E-37 T 29-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 MC49_RS13050 3546ea332fb8e1faec055f56a586dcff 171 PRINTS PR01171 Bacterial lipocalin signature 134 145 8.9E-37 T 29-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 MC49_RS13050 3546ea332fb8e1faec055f56a586dcff 171 PRINTS PR01171 Bacterial lipocalin signature 161 171 8.9E-37 T 29-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 MC49_RS13050 3546ea332fb8e1faec055f56a586dcff 171 PRINTS PR01171 Bacterial lipocalin signature 119 127 8.9E-37 T 29-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 MC49_RS13050 3546ea332fb8e1faec055f56a586dcff 171 PRINTS PR01171 Bacterial lipocalin signature 102 116 8.9E-37 T 29-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 MC49_RS13050 3546ea332fb8e1faec055f56a586dcff 171 PRINTS PR01171 Bacterial lipocalin signature 49 65 8.9E-37 T 29-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 MC49_RS13050 3546ea332fb8e1faec055f56a586dcff 171 Gene3D G3DSA:2.40.128.20 1 171 3.0E-41 T 29-03-2018 IPR012674 Calycin MC49_RS13050 3546ea332fb8e1faec055f56a586dcff 171 SUPERFAMILY SSF50814 9 170 9.04E-48 T 29-03-2018 IPR012674 Calycin MC49_RS19040 efa30c01433fb93abee385d574691afd 333 Gene3D G3DSA:3.40.50.2300 27 133 1.4E-13 T 29-03-2018 MC49_RS19040 efa30c01433fb93abee385d574691afd 333 Gene3D G3DSA:3.40.50.2300 134 333 4.2E-33 T 29-03-2018 MC49_RS19040 efa30c01433fb93abee385d574691afd 333 SUPERFAMILY SSF53822 27 329 2.55E-66 T 29-03-2018 IPR028082 Periplasmic binding protein-like I MC49_RS19040 efa30c01433fb93abee385d574691afd 333 Pfam PF13407 Periplasmic binding protein domain 29 288 3.4E-46 T 29-03-2018 IPR025997 Periplasmic binding protein MC49_RS16080 e393e1443d0be4a3272aa6f53384332e 225 Gene3D G3DSA:3.30.1380.10 10 190 3.0E-28 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MC49_RS16080 e393e1443d0be4a3272aa6f53384332e 225 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 22 178 1.6E-37 T 29-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 MC49_RS16080 e393e1443d0be4a3272aa6f53384332e 225 SUPERFAMILY SSF55166 18 178 3.81E-18 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MC49_RS16470 32b21cd6a137b6bb4766badc2a6bc433 333 Gene3D G3DSA:1.10.287.510 9 289 0.0028 T 29-03-2018 MC49_RS15850 bed357ff3ab7daacbac3ecca14799fb4 349 Gene3D G3DSA:3.20.20.70 7 349 3.5E-120 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS15850 bed357ff3ab7daacbac3ecca14799fb4 349 PIRSF PIRSF001361 1 349 8.8E-152 T 29-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 MC49_RS15850 bed357ff3ab7daacbac3ecca14799fb4 349 SUPERFAMILY SSF51569 7 346 2.41E-127 T 29-03-2018 MC49_RS15850 bed357ff3ab7daacbac3ecca14799fb4 349 Pfam PF00793 DAHP synthetase I family 43 336 2.4E-99 T 29-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 MC49_RS15850 bed357ff3ab7daacbac3ecca14799fb4 349 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 5 347 2.3E-164 T 29-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 MC49_RS00420 93d78ea1b186ab2a9e1160b480d7492a 392 Pfam PF00589 Phage integrase family 185 353 1.5E-43 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MC49_RS00420 93d78ea1b186ab2a9e1160b480d7492a 392 Gene3D G3DSA:1.10.443.10 186 366 5.4E-40 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MC49_RS00420 93d78ea1b186ab2a9e1160b480d7492a 392 Gene3D G3DSA:1.10.150.130 54 185 8.9E-13 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal MC49_RS00420 93d78ea1b186ab2a9e1160b480d7492a 392 SUPERFAMILY SSF56349 57 111 4.71E-50 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MC49_RS00420 93d78ea1b186ab2a9e1160b480d7492a 392 SUPERFAMILY SSF56349 139 361 4.71E-50 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MC49_RS12180 e2b43f220d7e305689abcefb45bbad5c 104 Gene3D G3DSA:1.25.40.10 3 98 2.9E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MC49_RS12180 e2b43f220d7e305689abcefb45bbad5c 104 Pfam PF13428 Tetratricopeptide repeat 21 59 1.8E-5 T 29-03-2018 MC49_RS12180 e2b43f220d7e305689abcefb45bbad5c 104 SUPERFAMILY SSF48452 21 82 1.03E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MC49_RS01600 4ef1da320623484f1d8f615e071a6ca2 283 Gene3D G3DSA:3.40.50.300 1 152 7.6E-11 T 29-03-2018 MC49_RS01600 4ef1da320623484f1d8f615e071a6ca2 283 PIRSF PIRSF005052 1 283 9.5E-115 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 MC49_RS01600 4ef1da320623484f1d8f615e071a6ca2 283 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 1 281 41.123 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 MC49_RS01600 4ef1da320623484f1d8f615e071a6ca2 283 SUPERFAMILY SSF52540 2 151 2.07E-12 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS01600 4ef1da320623484f1d8f615e071a6ca2 283 Pfam PF03668 P-loop ATPase protein family 1 282 5.3E-144 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 MC49_RS18895 2cf2eff33e6616de1554a374e6fdaacd 550 SUPERFAMILY SSF56821 1 547 8.39E-190 T 29-03-2018 IPR011254 Prismane-like GO:0003824|GO:0016491|GO:0055114 MC49_RS18895 2cf2eff33e6616de1554a374e6fdaacd 550 Gene3D G3DSA:3.40.50.2030 376 549 1.8E-61 T 29-03-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 MC49_RS18895 2cf2eff33e6616de1554a374e6fdaacd 550 Gene3D G3DSA:3.40.50.2030 235 375 2.2E-64 T 29-03-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 MC49_RS18895 2cf2eff33e6616de1554a374e6fdaacd 550 Gene3D G3DSA:1.20.1270.20 1 144 1.8E-35 T 29-03-2018 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 MC49_RS18895 2cf2eff33e6616de1554a374e6fdaacd 550 Hamap MF_00069 Hydroxylamine reductase [hcp]. 1 549 20.781 T 29-03-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 MC49_RS18895 2cf2eff33e6616de1554a374e6fdaacd 550 PIRSF PIRSF000076 1 550 1.8E-237 T 29-03-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 MC49_RS18895 2cf2eff33e6616de1554a374e6fdaacd 550 TIGRFAM TIGR01703 hybrid_clust: hydroxylamine reductase 1 547 1.4E-234 T 29-03-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 MC49_RS18895 2cf2eff33e6616de1554a374e6fdaacd 550 Pfam PF03063 Prismane/CO dehydrogenase family 1 544 1.6E-159 T 29-03-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 MC49_RS18895 2cf2eff33e6616de1554a374e6fdaacd 550 Gene3D G3DSA:1.20.1270.20 150 232 3.5E-20 T 29-03-2018 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 MC49_RS16370 547ecf8237c38fe43faf548a48cf8317 44 Pfam PF13998 MgrB protein 17 44 1.6E-17 T 29-03-2018 IPR020907 PhoP/PhoQ regulator MgrB MC49_RS17355 7747a9f74fae950ecb8841496a251d5c 70 SUPERFAMILY SSF50249 3 69 1.41E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS17355 7747a9f74fae950ecb8841496a251d5c 70 PIRSF PIRSF002599 1 70 2.4E-25 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 MC49_RS17355 7747a9f74fae950ecb8841496a251d5c 70 Gene3D G3DSA:2.40.50.140 4 70 9.0E-29 T 29-03-2018 MC49_RS17355 7747a9f74fae950ecb8841496a251d5c 70 SMART SM00357 6 70 7.9E-30 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 MC49_RS17355 7747a9f74fae950ecb8841496a251d5c 70 Pfam PF00313 'Cold-shock' DNA-binding domain 6 69 1.8E-32 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MC49_RS17355 7747a9f74fae950ecb8841496a251d5c 70 PRINTS PR00050 Cold shock protein signature 7 22 1.3E-17 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MC49_RS17355 7747a9f74fae950ecb8841496a251d5c 70 PRINTS PR00050 Cold shock protein signature 43 61 1.3E-17 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MC49_RS17355 7747a9f74fae950ecb8841496a251d5c 70 PRINTS PR00050 Cold shock protein signature 28 37 1.3E-17 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MC49_RS17355 7747a9f74fae950ecb8841496a251d5c 70 ProSitePatterns PS00352 'Cold-shock' domain signature. 18 37 - T 29-03-2018 IPR019844 Cold-shock conserved site MC49_RS01355 44e56bd1f99ba9f81e4caedf85bdc9da 100 Gene3D G3DSA:1.20.120.20 2 79 1.1E-5 T 29-03-2018 MC49_RS01355 44e56bd1f99ba9f81e4caedf85bdc9da 100 Pfam PF05957 Bacterial protein of unknown function (DUF883) 7 100 6.9E-31 T 29-03-2018 IPR010279 Protein of unknown function DUF883, ElaB MC49_RS10625 5620af524b5d9d88d584946aa8872d5e 151 Pfam PF02391 MoaE protein 9 121 1.2E-35 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MC49_RS10625 5620af524b5d9d88d584946aa8872d5e 151 Gene3D G3DSA:3.90.1170.40 2 150 7.0E-56 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MC49_RS10625 5620af524b5d9d88d584946aa8872d5e 151 SUPERFAMILY SSF54690 5 151 3.92E-53 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MC49_RS12015 9d702224d7a6facac98c642c3024f96a 161 Pfam PF14437 MafB19-like deaminase 1 142 1.7E-33 T 29-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 MC49_RS12015 9d702224d7a6facac98c642c3024f96a 161 Gene3D G3DSA:3.40.140.10 1 152 1.1E-47 T 29-03-2018 MC49_RS12015 9d702224d7a6facac98c642c3024f96a 161 SUPERFAMILY SSF53927 1 146 7.53E-54 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 MC49_RS12015 9d702224d7a6facac98c642c3024f96a 161 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 1 142 45.131 T 29-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 MC49_RS12015 9d702224d7a6facac98c642c3024f96a 161 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 46 83 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 MC49_RS07010 b17c7a1d8d6f3f9e97bd1a9554743c2c 173 Hamap MF_00984 Single-stranded DNA-binding protein. 6 117 40.576 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 MC49_RS07010 b17c7a1d8d6f3f9e97bd1a9554743c2c 173 SUPERFAMILY SSF50249 4 173 4.46E-64 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS07010 b17c7a1d8d6f3f9e97bd1a9554743c2c 173 Pfam PF00436 Single-strand binding protein family 6 112 6.2E-44 T 29-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 MC49_RS07010 b17c7a1d8d6f3f9e97bd1a9554743c2c 173 Gene3D G3DSA:2.40.50.140 1 118 1.0E-47 T 29-03-2018 MC49_RS07010 b17c7a1d8d6f3f9e97bd1a9554743c2c 173 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 3 173 3.5E-63 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 MC49_RS07435 a4266c3bc72a98c6045d05976b222965 360 Pfam PF13515 Fusaric acid resistance protein-like 46 165 4.1E-11 T 29-03-2018 MC49_RS08950 0bb377c18951d152fad2bb89cb65d0aa 442 Gene3D G3DSA:1.20.1250.20 8 205 1.7E-35 T 29-03-2018 MC49_RS08950 0bb377c18951d152fad2bb89cb65d0aa 442 PIRSF PIRSF002808 1 435 3.8E-125 T 29-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 MC49_RS08950 0bb377c18951d152fad2bb89cb65d0aa 442 Gene3D G3DSA:1.20.1250.20 227 430 1.5E-22 T 29-03-2018 MC49_RS08950 0bb377c18951d152fad2bb89cb65d0aa 442 SUPERFAMILY SSF103473 10 420 3.53E-73 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS08950 0bb377c18951d152fad2bb89cb65d0aa 442 Pfam PF07690 Major Facilitator Superfamily 25 385 3.8E-46 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS08340 3f8bbb85c0ca1a74a8ade06ca78565f0 196 SUPERFAMILY SSF52540 7 196 2.97E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS08340 3f8bbb85c0ca1a74a8ade06ca78565f0 196 PIRSF PIRSF015617 1 196 3.1E-70 T 29-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 MC49_RS08340 3f8bbb85c0ca1a74a8ade06ca78565f0 196 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 25 196 5.6E-74 T 29-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 MC49_RS08340 3f8bbb85c0ca1a74a8ade06ca78565f0 196 Gene3D G3DSA:3.40.50.300 6 196 6.2E-74 T 29-03-2018 MC49_RS08340 3f8bbb85c0ca1a74a8ade06ca78565f0 196 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 29 196 5.1E-63 T 29-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 MC49_RS08340 3f8bbb85c0ca1a74a8ade06ca78565f0 196 Pfam PF12557 Cob(I)alamin adenosyltransferase N terminal 3 21 2.3E-6 T 29-03-2018 IPR025826 Cob(I)alamin adenosyltransferase N-terminal domain KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 MC49_RS09730 7f370d3fc82bb8ee64c7360d6283202a 408 PIRSF PIRSF000044 1 408 1.5E-223 T 29-03-2018 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 MC49_RS09730 7f370d3fc82bb8ee64c7360d6283202a 408 Pfam PF00970 Oxidoreductase FAD-binding domain 205 267 5.6E-9 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 MC49_RS09730 7f370d3fc82bb8ee64c7360d6283202a 408 SUPERFAMILY SSF52343 256 403 3.93E-36 T 29-03-2018 MC49_RS09730 7f370d3fc82bb8ee64c7360d6283202a 408 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 38 115 3.2E-11 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MC49_RS09730 7f370d3fc82bb8ee64c7360d6283202a 408 TIGRFAM TIGR01941 nqrF: NADH:ubiquinone oxidoreductase, Na(+)-translocating, F subunit 4 408 1.6E-230 T 29-03-2018 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 MC49_RS09730 7f370d3fc82bb8ee64c7360d6283202a 408 Gene3D G3DSA:3.10.20.30 27 137 6.7E-22 T 29-03-2018 IPR012675 Beta-grasp domain MC49_RS09730 7f370d3fc82bb8ee64c7360d6283202a 408 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 277 296 6.6E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MC49_RS09730 7f370d3fc82bb8ee64c7360d6283202a 408 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 315 326 6.6E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MC49_RS09730 7f370d3fc82bb8ee64c7360d6283202a 408 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 210 217 6.6E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MC49_RS09730 7f370d3fc82bb8ee64c7360d6283202a 408 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 243 252 6.6E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MC49_RS09730 7f370d3fc82bb8ee64c7360d6283202a 408 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 303 312 6.6E-6 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MC49_RS09730 7f370d3fc82bb8ee64c7360d6283202a 408 Gene3D G3DSA:3.40.50.80 258 402 1.2E-28 T 29-03-2018 MC49_RS09730 7f370d3fc82bb8ee64c7360d6283202a 408 Hamap MF_00430 Na(+)-translocating NADH-quinone reductase subunit F [nqrF]. 2 408 63.644 T 29-03-2018 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 MC49_RS09730 7f370d3fc82bb8ee64c7360d6283202a 408 Pfam PF00175 Oxidoreductase NAD-binding domain 278 387 1.4E-17 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MC49_RS09730 7f370d3fc82bb8ee64c7360d6283202a 408 SUPERFAMILY SSF63380 106 273 4.33E-37 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MC49_RS09730 7f370d3fc82bb8ee64c7360d6283202a 408 Gene3D G3DSA:2.40.30.10 138 257 1.7E-32 T 29-03-2018 MC49_RS09730 7f370d3fc82bb8ee64c7360d6283202a 408 SUPERFAMILY SSF54292 41 125 1.01E-22 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MC49_RS02955 f97a72aee4289c7b6a021f6ce09108af 211 Pfam PF01810 LysE type translocator 18 209 2.0E-37 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MC49_RS02955 f97a72aee4289c7b6a021f6ce09108af 211 PIRSF PIRSF006324 4 211 3.0E-48 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MC49_RS09480 f3480817a9a2e8dee13a825a3b6ddaa9 923 Gene3D G3DSA:2.160.20.20 50 607 6.6E-26 T 29-03-2018 IPR012332 P22 tailspike C-terminal domain-like MC49_RS09480 f3480817a9a2e8dee13a825a3b6ddaa9 923 PRINTS PR01484 Pertactin virulence factor family signature 839 860 1.0E-18 T 29-03-2018 IPR003991 Pertactin virulence factor family GO:0007155 MC49_RS09480 f3480817a9a2e8dee13a825a3b6ddaa9 923 PRINTS PR01484 Pertactin virulence factor family signature 702 726 1.0E-18 T 29-03-2018 IPR003991 Pertactin virulence factor family GO:0007155 MC49_RS09480 f3480817a9a2e8dee13a825a3b6ddaa9 923 PRINTS PR01484 Pertactin virulence factor family signature 878 903 1.0E-18 T 29-03-2018 IPR003991 Pertactin virulence factor family GO:0007155 MC49_RS09480 f3480817a9a2e8dee13a825a3b6ddaa9 923 PRINTS PR01484 Pertactin virulence factor family signature 903 923 1.0E-18 T 29-03-2018 IPR003991 Pertactin virulence factor family GO:0007155 MC49_RS09480 f3480817a9a2e8dee13a825a3b6ddaa9 923 PRINTS PR01484 Pertactin virulence factor family signature 810 833 1.0E-18 T 29-03-2018 IPR003991 Pertactin virulence factor family GO:0007155 MC49_RS09480 f3480817a9a2e8dee13a825a3b6ddaa9 923 PRINTS PR01484 Pertactin virulence factor family signature 641 659 1.0E-18 T 29-03-2018 IPR003991 Pertactin virulence factor family GO:0007155 MC49_RS09480 f3480817a9a2e8dee13a825a3b6ddaa9 923 SUPERFAMILY SSF103515 637 923 1.12E-51 T 29-03-2018 IPR005546 Autotransporter beta-domain MC49_RS09480 f3480817a9a2e8dee13a825a3b6ddaa9 923 SMART SM00869 662 912 2.1E-43 T 29-03-2018 IPR005546 Autotransporter beta-domain MC49_RS09480 f3480817a9a2e8dee13a825a3b6ddaa9 923 SUPERFAMILY SSF51126 256 602 1.19E-26 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor MC49_RS09480 f3480817a9a2e8dee13a825a3b6ddaa9 923 Gene3D G3DSA:2.40.128.130 621 923 5.5E-52 T 29-03-2018 MC49_RS09480 f3480817a9a2e8dee13a825a3b6ddaa9 923 Pfam PF03797 Autotransporter beta-domain 665 901 6.8E-48 T 29-03-2018 IPR005546 Autotransporter beta-domain MC49_RS09480 f3480817a9a2e8dee13a825a3b6ddaa9 923 Pfam PF16168 Adhesin of bacterial autotransporter system, probable stalk 136 182 3.5E-8 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system MC49_RS09480 f3480817a9a2e8dee13a825a3b6ddaa9 923 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 498 923 3.3E-108 T 29-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 MC49_RS09480 f3480817a9a2e8dee13a825a3b6ddaa9 923 Pfam PF03212 Pertactin 483 601 2.5E-21 T 29-03-2018 IPR004899 Pertactin, central region MC49_RS04685 c767c3f46d22993783fdae9788689e92 224 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 136 158 - T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MC49_RS04685 c767c3f46d22993783fdae9788689e92 224 Gene3D G3DSA:3.20.20.70 1 220 3.9E-86 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS04685 c767c3f46d22993783fdae9788689e92 224 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 5 216 4.9E-97 T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MC49_RS04685 c767c3f46d22993783fdae9788689e92 224 Pfam PF00834 Ribulose-phosphate 3 epimerase family 6 203 1.7E-91 T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MC49_RS04685 c767c3f46d22993783fdae9788689e92 224 SUPERFAMILY SSF51366 4 218 1.1E-73 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MC49_RS04685 c767c3f46d22993783fdae9788689e92 224 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 33 47 - T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MC49_RS04685 c767c3f46d22993783fdae9788689e92 224 PIRSF PIRSF001461 1 224 8.9E-106 T 29-03-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MC49_RS00680 85ec26df5348c0867b3627f7f51f69be 287 Gene3D G3DSA:3.10.129.10 2 116 8.8E-43 T 29-03-2018 MC49_RS00680 85ec26df5348c0867b3627f7f51f69be 287 Pfam PF13622 Thioesterase-like superfamily 33 281 1.9E-59 T 29-03-2018 MC49_RS00680 85ec26df5348c0867b3627f7f51f69be 287 TIGRFAM TIGR00189 tesB: acyl-CoA thioesterase II 13 283 1.1E-96 T 29-03-2018 IPR003703 Acyl-CoA thioesterase GO:0006637|GO:0047617 Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247 MC49_RS00680 85ec26df5348c0867b3627f7f51f69be 287 SUPERFAMILY SSF54637 116 283 7.7E-55 T 29-03-2018 IPR029069 HotDog domain MC49_RS00680 85ec26df5348c0867b3627f7f51f69be 287 Gene3D G3DSA:3.10.129.10 131 286 2.4E-52 T 29-03-2018 MC49_RS00680 85ec26df5348c0867b3627f7f51f69be 287 SUPERFAMILY SSF54637 5 114 1.25E-41 T 29-03-2018 IPR029069 HotDog domain MC49_RS10825 ee160900127227b9e9e1834699edfcd4 92 Pfam PF00677 Lumazine binding domain 6 89 7.4E-17 T 29-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MC49_RS10825 ee160900127227b9e9e1834699edfcd4 92 SUPERFAMILY SSF63380 4 89 7.91E-23 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MC49_RS10825 ee160900127227b9e9e1834699edfcd4 92 Gene3D G3DSA:2.40.30.20 4 91 1.4E-22 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS18885 f39836c9b62eba701738056850299f4d 129 SUPERFAMILY SSF54427 5 112 2.58E-10 T 29-03-2018 IPR032710 NTF2-like domain MC49_RS18885 f39836c9b62eba701738056850299f4d 129 Gene3D G3DSA:3.10.450.50 3 118 6.6E-8 T 29-03-2018 MC49_RS18885 f39836c9b62eba701738056850299f4d 129 Pfam PF12680 SnoaL-like domain 20 108 3.5E-6 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain MC49_RS17560 9460c8112f699786b4fabd55249f77c0 220 Pfam PF11041 Protein of unknown function (DUF2612) 15 196 1.1E-55 T 29-03-2018 IPR021283 Protein of unknown function DUF2612 MC49_RS16170 7d1799ffa09246867080d101595f4e1f 487 Pfam PF01435 Peptidase family M48 75 259 5.2E-25 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 MC49_RS16170 7d1799ffa09246867080d101595f4e1f 487 Gene3D G3DSA:3.30.2010.10 64 144 1.3E-16 T 29-03-2018 MC49_RS16170 7d1799ffa09246867080d101595f4e1f 487 Pfam PF14559 Tetratricopeptide repeat 358 419 9.2E-9 T 29-03-2018 MC49_RS16170 7d1799ffa09246867080d101595f4e1f 487 Gene3D G3DSA:1.25.40.10 392 482 3.1E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MC49_RS16170 7d1799ffa09246867080d101595f4e1f 487 Hamap MF_00997 Beta-barrel assembly-enhancing protease [bepA]. 4 486 39.009 T 29-03-2018 IPR030873 Beta-barrel assembly-enhancing protease GO:0006508|GO:0008237|GO:0016020|GO:0061077 MC49_RS16170 7d1799ffa09246867080d101595f4e1f 487 Gene3D G3DSA:1.25.40.10 369 391 2.6E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MC49_RS16170 7d1799ffa09246867080d101595f4e1f 487 SUPERFAMILY SSF48452 312 457 4.02E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MC49_RS16170 7d1799ffa09246867080d101595f4e1f 487 Gene3D G3DSA:1.25.40.10 305 368 1.9E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MC49_RS15615 c632672a5c9cf3d9f0e76b71be7a1a2f 321 Gene3D G3DSA:1.10.3720.10 3 303 3.2E-42 T 29-03-2018 MC49_RS15615 c632672a5c9cf3d9f0e76b71be7a1a2f 321 SUPERFAMILY SSF161098 68 138 2.62E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS15615 c632672a5c9cf3d9f0e76b71be7a1a2f 321 SUPERFAMILY SSF161098 178 301 2.62E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS15615 c632672a5c9cf3d9f0e76b71be7a1a2f 321 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 311 9.5E-39 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS13460 8989a30aa7a0024bed58744453756ba6 299 Pfam PF14526 Integron-associated effector binding protein 130 292 1.0E-7 T 29-03-2018 IPR029441 Integron-associated effector binding protein MC49_RS13460 8989a30aa7a0024bed58744453756ba6 299 SUPERFAMILY SSF46689 57 108 2.78E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS13460 8989a30aa7a0024bed58744453756ba6 299 SMART SM00342 21 104 2.1E-28 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MC49_RS13460 8989a30aa7a0024bed58744453756ba6 299 Pfam PF12833 Helix-turn-helix domain 28 105 6.2E-18 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MC49_RS13460 8989a30aa7a0024bed58744453756ba6 299 Gene3D G3DSA:1.10.10.60 58 115 4.8E-10 T 29-03-2018 MC49_RS13460 8989a30aa7a0024bed58744453756ba6 299 SUPERFAMILY SSF46689 7 55 3.49E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS13460 8989a30aa7a0024bed58744453756ba6 299 Gene3D G3DSA:1.10.10.60 3 57 1.3E-16 T 29-03-2018 MC49_RS13460 8989a30aa7a0024bed58744453756ba6 299 Gene3D G3DSA:3.20.80.10 124 298 2.2E-8 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain MC49_RS13460 8989a30aa7a0024bed58744453756ba6 299 SUPERFAMILY SSF55136 128 292 5.75E-7 T 29-03-2018 MC49_RS11105 e63126efe71b36e359a0f7b2079bff1e 286 TIGRFAM TIGR00790 fnt: formate/nitrite transporter 27 281 7.5E-91 T 29-03-2018 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 MC49_RS11105 e63126efe71b36e359a0f7b2079bff1e 286 ProSitePatterns PS01005 Formate and nitrite transporters signature 1. 84 93 - T 29-03-2018 IPR024002 Formate/nitrite transporter, conserved site MC49_RS11105 e63126efe71b36e359a0f7b2079bff1e 286 TIGRFAM TIGR04060 formate_focA: formate transporter FocA 15 280 1.0E-122 T 29-03-2018 IPR023999 Formate transporter FocA, putative GO:0015499|GO:0015724|GO:0016021 MC49_RS11105 e63126efe71b36e359a0f7b2079bff1e 286 ProSitePatterns PS01006 Formate and nitrite transporters signature 2. 169 179 - T 29-03-2018 IPR024002 Formate/nitrite transporter, conserved site MC49_RS11105 e63126efe71b36e359a0f7b2079bff1e 286 Gene3D G3DSA:1.20.1080.10 10 286 8.7E-78 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 MC49_RS11105 e63126efe71b36e359a0f7b2079bff1e 286 Pfam PF01226 Formate/nitrite transporter 17 277 5.3E-76 T 29-03-2018 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 MC49_RS10080 550698b6b5c963ad67ed85f6153889c7 321 SUPERFAMILY SSF102114 53 317 4.84E-68 T 29-03-2018 MC49_RS10080 550698b6b5c963ad67ed85f6153889c7 321 PIRSF PIRSF005963 2 321 2.0E-130 T 29-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MC49_RS10080 550698b6b5c963ad67ed85f6153889c7 321 TIGRFAM TIGR00510 lipA: lipoyl synthase 21 321 1.2E-157 T 29-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MC49_RS10080 550698b6b5c963ad67ed85f6153889c7 321 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 25 73 2.6E-8 T 29-03-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MC49_RS10080 550698b6b5c963ad67ed85f6153889c7 321 Hamap MF_00206 Lipoyl synthase [lipA]. 1 321 155.919 T 29-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MC49_RS10080 550698b6b5c963ad67ed85f6153889c7 321 Pfam PF04055 Radical SAM superfamily 91 251 9.6E-15 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MC49_RS10080 550698b6b5c963ad67ed85f6153889c7 321 Gene3D G3DSA:3.20.20.70 23 302 2.6E-28 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS10080 550698b6b5c963ad67ed85f6153889c7 321 SMART SM00729 84 293 1.7E-16 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MC49_RS14950 06a1beb95ce74bdbe40e6ea60e544a5a 77 ProDom PD336997 PRECURSOR SIGNAL MEMBRANE OUTER YNFD ESCHERICHIA EXPORTED PP0087 COLI PP0090 1 76 7.0E-13 T 29-03-2018 IPR010595 Protein of unknown function DUF1161 MC49_RS14950 06a1beb95ce74bdbe40e6ea60e544a5a 77 Pfam PF06649 Protein of unknown function (DUF1161) 23 76 1.6E-22 T 29-03-2018 IPR010595 Protein of unknown function DUF1161 MC49_RS00465 9ae34cd94a9343fca3faa6507f4927cb 174 Gene3D G3DSA:3.40.50.7700 5 170 8.0E-65 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 MC49_RS00465 9ae34cd94a9343fca3faa6507f4927cb 174 PIRSF PIRSF001338 10 173 2.8E-66 T 29-03-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 MC49_RS00465 9ae34cd94a9343fca3faa6507f4927cb 174 SMART SM01001 13 164 8.9E-101 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 MC49_RS00465 9ae34cd94a9343fca3faa6507f4927cb 174 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 15 168 31.901 T 29-03-2018 IPR033747 Class I PurE MC49_RS00465 9ae34cd94a9343fca3faa6507f4927cb 174 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 15 169 5.8E-65 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 MC49_RS00465 9ae34cd94a9343fca3faa6507f4927cb 174 SUPERFAMILY SSF52255 14 171 1.44E-65 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 MC49_RS00465 9ae34cd94a9343fca3faa6507f4927cb 174 Pfam PF00731 AIR carboxylase 14 162 1.4E-63 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 MC49_RS14200 cc6722bbcc30f862b9c16f7b2e63f887 517 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 271 452 2.0E-21 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 MC49_RS14200 cc6722bbcc30f862b9c16f7b2e63f887 517 Hamap MF_02053 Autoinducer-2 kinase [lsrK]. 1 516 77.341 T 29-03-2018 IPR033676 Autoinducer-2 kinase GO:0009372|GO:0071518 MC49_RS14200 cc6722bbcc30f862b9c16f7b2e63f887 517 Gene3D G3DSA:3.30.420.40 1 243 3.4E-60 T 29-03-2018 MC49_RS14200 cc6722bbcc30f862b9c16f7b2e63f887 517 SUPERFAMILY SSF53067 248 498 5.06E-49 T 29-03-2018 MC49_RS14200 cc6722bbcc30f862b9c16f7b2e63f887 517 PIRSF PIRSF000538 1 505 3.8E-117 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MC49_RS14200 cc6722bbcc30f862b9c16f7b2e63f887 517 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 2 246 6.5E-49 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 MC49_RS14200 cc6722bbcc30f862b9c16f7b2e63f887 517 Gene3D G3DSA:3.30.420.40 244 502 9.5E-44 T 29-03-2018 MC49_RS14200 cc6722bbcc30f862b9c16f7b2e63f887 517 SUPERFAMILY SSF53067 1 249 2.4E-57 T 29-03-2018 MC49_RS07335 120d970b3c69a3ea0d0f79a949f93f7c 239 SUPERFAMILY SSF53167 3 234 4.32E-93 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MC49_RS07335 120d970b3c69a3ea0d0f79a949f93f7c 239 Pfam PF01048 Phosphorylase superfamily 15 220 3.5E-39 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MC49_RS07335 120d970b3c69a3ea0d0f79a949f93f7c 239 Hamap MF_01627 Purine nucleoside phosphorylase DeoD-type [deoD]. 2 235 52.172 T 29-03-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 MC49_RS07335 120d970b3c69a3ea0d0f79a949f93f7c 239 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 62 77 - T 29-03-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 MC49_RS07335 120d970b3c69a3ea0d0f79a949f93f7c 239 TIGRFAM TIGR00107 deoD: purine nucleoside phosphorylase 5 234 6.3E-122 T 29-03-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 MC49_RS07335 120d970b3c69a3ea0d0f79a949f93f7c 239 Gene3D G3DSA:3.40.50.1580 9 235 4.6E-56 T 29-03-2018 MC49_RS06180 eed5b628a2b8a77de88e5ee2522a2f97 280 SUPERFAMILY SSF53335 9 279 3.32E-98 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS06180 eed5b628a2b8a77de88e5ee2522a2f97 280 Gene3D G3DSA:3.40.50.150 1 280 1.8E-91 T 29-03-2018 MC49_RS06180 eed5b628a2b8a77de88e5ee2522a2f97 280 Pfam PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ 33 278 4.1E-111 T 29-03-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 MC49_RS06180 eed5b628a2b8a77de88e5ee2522a2f97 280 Hamap MF_00934 Ribosomal RNA large subunit methyltransferase J [rlmJ]. 2 266 41.883 T 29-03-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 MC49_RS14440 28bebd314cb55237e1d2838e8ea1b862 415 PIRSF PIRSF001109 2 414 2.6E-164 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MC49_RS14440 28bebd314cb55237e1d2838e8ea1b862 415 SMART SM00996 3 413 2.5E-113 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MC49_RS14440 28bebd314cb55237e1d2838e8ea1b862 415 Gene3D G3DSA:3.40.50.1480 3 134 4.5E-40 T 29-03-2018 MC49_RS14440 28bebd314cb55237e1d2838e8ea1b862 415 Gene3D G3DSA:3.40.50.1480 135 204 1.2E-11 T 29-03-2018 MC49_RS14440 28bebd314cb55237e1d2838e8ea1b862 415 SUPERFAMILY SSF51735 185 347 2.26E-65 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS14440 28bebd314cb55237e1d2838e8ea1b862 415 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 7 411 7.7E-170 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MC49_RS14440 28bebd314cb55237e1d2838e8ea1b862 415 Gene3D G3DSA:3.40.50.1480 205 397 4.6E-59 T 29-03-2018 MC49_RS14440 28bebd314cb55237e1d2838e8ea1b862 415 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 185 346 6.8E-54 T 29-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MC49_RS14440 28bebd314cb55237e1d2838e8ea1b862 415 SMART SM00997 185 346 2.0E-101 T 29-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MC49_RS14440 28bebd314cb55237e1d2838e8ea1b862 415 SUPERFAMILY SSF52283 3 184 1.02E-80 T 29-03-2018 MC49_RS14440 28bebd314cb55237e1d2838e8ea1b862 415 SUPERFAMILY SSF52283 347 411 1.02E-80 T 29-03-2018 MC49_RS14440 28bebd314cb55237e1d2838e8ea1b862 415 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 207 223 - T 29-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MC49_RS14440 28bebd314cb55237e1d2838e8ea1b862 415 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 7 135 1.3E-24 T 29-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MC49_RS16265 5a3e647dc493b06ea70ce7251f4f2786 487 Gene3D G3DSA:3.10.580.10 170 297 1.3E-14 T 29-03-2018 MC49_RS16265 5a3e647dc493b06ea70ce7251f4f2786 487 Pfam PF01769 Divalent cation transporter 358 479 1.6E-24 T 29-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 MC49_RS16265 5a3e647dc493b06ea70ce7251f4f2786 487 SUPERFAMILY SSF158791 61 170 1.31E-23 T 29-03-2018 MC49_RS16265 5a3e647dc493b06ea70ce7251f4f2786 487 SUPERFAMILY SSF54631 174 313 2.99E-25 T 29-03-2018 MC49_RS16265 5a3e647dc493b06ea70ce7251f4f2786 487 SMART SM00924 71 174 5.5E-28 T 29-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain MC49_RS16265 5a3e647dc493b06ea70ce7251f4f2786 487 Gene3D G3DSA:1.10.357.20 314 487 2.0E-33 T 29-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 MC49_RS16265 5a3e647dc493b06ea70ce7251f4f2786 487 SUPERFAMILY SSF161093 316 486 1.83E-47 T 29-03-2018 MC49_RS16265 5a3e647dc493b06ea70ce7251f4f2786 487 SMART SM00116 245 293 6.7E-5 T 29-03-2018 IPR000644 CBS domain MC49_RS16265 5a3e647dc493b06ea70ce7251f4f2786 487 Gene3D G3DSA:1.25.60.10 43 169 8.8E-16 T 29-03-2018 MC49_RS16265 5a3e647dc493b06ea70ce7251f4f2786 487 Pfam PF03448 MgtE intracellular N domain 71 172 1.7E-21 T 29-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain MC49_RS16265 5a3e647dc493b06ea70ce7251f4f2786 487 TIGRFAM TIGR00400 mgtE: magnesium transporter 60 486 2.8E-77 T 29-03-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 MC49_RS16265 5a3e647dc493b06ea70ce7251f4f2786 487 Pfam PF00571 CBS domain 238 292 1.5E-7 T 29-03-2018 IPR000644 CBS domain MC49_RS18745 6fd068cac4b3c34887921752466c8985 200 SUPERFAMILY SSF52016 1 193 5.49E-59 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel MC49_RS18745 6fd068cac4b3c34887921752466c8985 200 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 199 44.78 T 29-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 MC49_RS18745 6fd068cac4b3c34887921752466c8985 200 Gene3D G3DSA:3.20.19.10 1 176 2.1E-48 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel MC49_RS18745 6fd068cac4b3c34887921752466c8985 200 Pfam PF00694 Aconitase C-terminal domain 1 125 2.5E-40 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 MC49_RS18745 6fd068cac4b3c34887921752466c8985 200 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 188 2.0E-96 T 29-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 MC49_RS16355 478f279df0b46cb6c1b8b24d44e2285a 69 Pfam PF00313 'Cold-shock' DNA-binding domain 5 68 2.6E-33 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MC49_RS16355 478f279df0b46cb6c1b8b24d44e2285a 69 ProSitePatterns PS00352 'Cold-shock' domain signature. 17 36 - T 29-03-2018 IPR019844 Cold-shock conserved site MC49_RS16355 478f279df0b46cb6c1b8b24d44e2285a 69 PIRSF PIRSF002599 1 69 2.3E-25 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 MC49_RS16355 478f279df0b46cb6c1b8b24d44e2285a 69 SUPERFAMILY SSF50249 3 68 3.27E-26 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS16355 478f279df0b46cb6c1b8b24d44e2285a 69 PRINTS PR00050 Cold shock protein signature 6 21 7.2E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MC49_RS16355 478f279df0b46cb6c1b8b24d44e2285a 69 PRINTS PR00050 Cold shock protein signature 27 36 7.2E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MC49_RS16355 478f279df0b46cb6c1b8b24d44e2285a 69 PRINTS PR00050 Cold shock protein signature 42 60 7.2E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MC49_RS16355 478f279df0b46cb6c1b8b24d44e2285a 69 SMART SM00357 5 69 1.2E-31 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 MC49_RS16355 478f279df0b46cb6c1b8b24d44e2285a 69 Gene3D G3DSA:2.40.50.140 4 69 7.7E-30 T 29-03-2018 MC49_RS02705 f03f64d775dac9571217658386043b91 349 Pfam PF01312 FlhB HrpN YscU SpaS Family 3 332 6.3E-85 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MC49_RS02705 f03f64d775dac9571217658386043b91 349 Gene3D G3DSA:3.40.1690.10 206 341 1.8E-35 T 29-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal MC49_RS02705 f03f64d775dac9571217658386043b91 349 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 260 275 2.5E-29 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MC49_RS02705 f03f64d775dac9571217658386043b91 349 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 5 27 2.5E-29 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MC49_RS02705 f03f64d775dac9571217658386043b91 349 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 216 233 2.5E-29 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MC49_RS02705 f03f64d775dac9571217658386043b91 349 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 196 214 2.5E-29 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MC49_RS02705 f03f64d775dac9571217658386043b91 349 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 290 311 2.5E-29 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MC49_RS02705 f03f64d775dac9571217658386043b91 349 SUPERFAMILY SSF160544 232 338 2.75E-23 T 29-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal MC49_RS12125 9752d712945a220a9878452b908a37b2 172 Gene3D G3DSA:1.10.287.110 1 84 5.4E-10 T 29-03-2018 IPR001623 DnaJ domain MC49_RS12125 9752d712945a220a9878452b908a37b2 172 Hamap MF_00682 Co-chaperone protein HscB [hscB]. 1 169 23.957 T 29-03-2018 IPR004640 Co-chaperone Hsc20 GO:0001671|GO:0051087|GO:0097428 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 MC49_RS12125 9752d712945a220a9878452b908a37b2 172 SMART SM00271 1 66 1.5E-7 T 29-03-2018 IPR001623 DnaJ domain MC49_RS12125 9752d712945a220a9878452b908a37b2 172 TIGRFAM TIGR00714 hscB: Fe-S protein assembly co-chaperone HscB 13 168 1.3E-52 T 29-03-2018 IPR004640 Co-chaperone Hsc20 GO:0001671|GO:0051087|GO:0097428 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 MC49_RS12125 9752d712945a220a9878452b908a37b2 172 SUPERFAMILY SSF46565 1 75 1.11E-17 T 29-03-2018 IPR001623 DnaJ domain MC49_RS12125 9752d712945a220a9878452b908a37b2 172 Pfam PF07743 HSCB C-terminal oligomerisation domain 88 162 9.3E-18 T 29-03-2018 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 MC49_RS12125 9752d712945a220a9878452b908a37b2 172 Gene3D G3DSA:1.20.1280.20 85 168 8.4E-24 T 29-03-2018 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 MC49_RS12125 9752d712945a220a9878452b908a37b2 172 Pfam PF00226 DnaJ domain 9 70 1.2E-6 T 29-03-2018 IPR001623 DnaJ domain MC49_RS12125 9752d712945a220a9878452b908a37b2 172 SUPERFAMILY SSF47144 77 170 1.57E-25 T 29-03-2018 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 MC49_RS11515 999a9bf8965c44136d61a6823503b772 177 Gene3D G3DSA:3.40.630.30 6 145 4.7E-17 T 29-03-2018 MC49_RS11515 999a9bf8965c44136d61a6823503b772 177 Pfam PF00583 Acetyltransferase (GNAT) family 18 125 1.8E-9 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MC49_RS11515 999a9bf8965c44136d61a6823503b772 177 SUPERFAMILY SSF55729 15 134 7.44E-16 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS16590 f489dc5f4bfb5ff506b7fb06a8082ca3 191 PIRSF PIRSF017340 1 169 1.9E-63 T 29-03-2018 IPR024195 NUDIX hydrolase, YfcD, predicted GO:0016817 MC49_RS16590 f489dc5f4bfb5ff506b7fb06a8082ca3 191 Pfam PF00293 NUDIX domain 34 147 7.4E-16 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MC49_RS16590 f489dc5f4bfb5ff506b7fb06a8082ca3 191 SUPERFAMILY SSF55811 8 163 1.9E-33 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MC49_RS16590 f489dc5f4bfb5ff506b7fb06a8082ca3 191 Gene3D G3DSA:3.90.79.10 1 178 1.5E-34 T 29-03-2018 MC49_RS02810 d505f7ddd3e4360104fd0de640f3d672 347 Gene3D G3DSA:3.40.190.10 18 190 7.3E-31 T 29-03-2018 MC49_RS02810 d505f7ddd3e4360104fd0de640f3d672 347 Pfam PF13343 Bacterial extracellular solute-binding protein 76 322 4.9E-37 T 29-03-2018 MC49_RS02810 d505f7ddd3e4360104fd0de640f3d672 347 PIRSF PIRSF019574 1 347 9.3E-129 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MC49_RS02810 d505f7ddd3e4360104fd0de640f3d672 347 Gene3D G3DSA:3.40.190.10 191 312 1.6E-21 T 29-03-2018 MC49_RS02810 d505f7ddd3e4360104fd0de640f3d672 347 SUPERFAMILY SSF53850 26 344 1.21E-93 T 29-03-2018 MC49_RS02810 d505f7ddd3e4360104fd0de640f3d672 347 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 148 162 2.1E-92 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MC49_RS02810 d505f7ddd3e4360104fd0de640f3d672 347 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 203 222 2.1E-92 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MC49_RS02810 d505f7ddd3e4360104fd0de640f3d672 347 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 247 266 2.1E-92 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MC49_RS02810 d505f7ddd3e4360104fd0de640f3d672 347 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 122 138 2.1E-92 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MC49_RS02810 d505f7ddd3e4360104fd0de640f3d672 347 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 166 185 2.1E-92 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MC49_RS02810 d505f7ddd3e4360104fd0de640f3d672 347 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 292 318 2.1E-92 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MC49_RS02810 d505f7ddd3e4360104fd0de640f3d672 347 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 47 68 2.1E-92 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MC49_RS02810 d505f7ddd3e4360104fd0de640f3d672 347 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 91 104 2.1E-92 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MC49_RS02810 d505f7ddd3e4360104fd0de640f3d672 347 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 31 47 2.1E-92 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MC49_RS02810 d505f7ddd3e4360104fd0de640f3d672 347 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 75 89 2.1E-92 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 MC49_RS14730 f53c736b9ad7e63b8a0a2339394fcc09 319 SUPERFAMILY SSF46785 11 128 1.2E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS14730 f53c736b9ad7e63b8a0a2339394fcc09 319 Gene3D G3DSA:3.40.190.10 193 278 1.3E-23 T 29-03-2018 MC49_RS14730 f53c736b9ad7e63b8a0a2339394fcc09 319 Gene3D G3DSA:3.40.190.10 105 192 4.8E-15 T 29-03-2018 MC49_RS14730 f53c736b9ad7e63b8a0a2339394fcc09 319 Gene3D G3DSA:1.10.10.10 19 100 3.1E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS14730 f53c736b9ad7e63b8a0a2339394fcc09 319 SUPERFAMILY SSF53850 105 310 3.26E-45 T 29-03-2018 MC49_RS14730 f53c736b9ad7e63b8a0a2339394fcc09 319 Pfam PF03466 LysR substrate binding domain 104 307 3.2E-41 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS14730 f53c736b9ad7e63b8a0a2339394fcc09 319 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 24 79 2.3E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS02220 72e91d030d637c6149ca7bdd03137b3b 380 Pfam PF02661 Fic/DOC family 110 210 2.7E-20 T 29-03-2018 IPR003812 Fido domain MC49_RS02220 72e91d030d637c6149ca7bdd03137b3b 380 Gene3D G3DSA:1.10.3290.10 22 282 5.5E-50 T 29-03-2018 IPR003812 Fido domain MC49_RS02220 72e91d030d637c6149ca7bdd03137b3b 380 SUPERFAMILY SSF140931 87 275 3.66E-34 T 29-03-2018 IPR003812 Fido domain MC49_RS11800 4eebc4403c826e4d1c9c92bc6c1e990b 317 PIRSF PIRSF005427 1 316 1.5E-72 T 29-03-2018 IPR005588 MucB/RseB MC49_RS11800 4eebc4403c826e4d1c9c92bc6c1e990b 317 Gene3D G3DSA:2.50.20.10 19 252 3.9E-16 T 29-03-2018 MC49_RS11800 4eebc4403c826e4d1c9c92bc6c1e990b 317 Pfam PF17188 MucB/RseB C-terminal domain 220 312 1.1E-26 T 29-03-2018 IPR033436 MucB/RseB, C-terminal MC49_RS11800 4eebc4403c826e4d1c9c92bc6c1e990b 317 Pfam PF03888 MucB/RseB N-terminal domain 26 199 7.8E-53 T 29-03-2018 IPR033434 MucB/RseB, N-terminal MC49_RS05255 0362cf330c1f1696f98ac8ad539a4c6b 327 SMART SM00283 50 297 1.4E-66 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MC49_RS05255 0362cf330c1f1696f98ac8ad539a4c6b 327 Gene3D G3DSA:1.10.287.950 107 301 1.8E-44 T 29-03-2018 MC49_RS05255 0362cf330c1f1696f98ac8ad539a4c6b 327 Gene3D G3DSA:1.10.287.950 2 106 7.8E-12 T 29-03-2018 MC49_RS05255 0362cf330c1f1696f98ac8ad539a4c6b 327 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 108 264 3.5E-45 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MC49_RS05255 0362cf330c1f1696f98ac8ad539a4c6b 327 SUPERFAMILY SSF58104 17 298 2.09E-60 T 29-03-2018 MC49_RS05255 0362cf330c1f1696f98ac8ad539a4c6b 327 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 177 206 2.7E-44 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS05255 0362cf330c1f1696f98ac8ad539a4c6b 327 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 71 100 2.7E-44 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS05255 0362cf330c1f1696f98ac8ad539a4c6b 327 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 225 254 2.7E-44 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS05255 0362cf330c1f1696f98ac8ad539a4c6b 327 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 148 175 2.7E-44 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS01850 5a21c67c6b50d2cd1d287751a83439e8 323 Pfam PF02687 FtsX-like permease family 224 313 7.1E-7 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MC49_RS01850 5a21c67c6b50d2cd1d287751a83439e8 323 PIRSF PIRSF003097 22 319 3.9E-90 T 29-03-2018 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 MC49_RS18400 8151a5452d18589292f0bde675cb31a4 230 SUPERFAMILY SSF52833 88 229 3.32E-32 T 29-03-2018 IPR012336 Thioredoxin-like fold MC49_RS18400 8151a5452d18589292f0bde675cb31a4 230 Gene3D G3DSA:3.40.30.10 99 230 2.4E-18 T 29-03-2018 MC49_RS18400 8151a5452d18589292f0bde675cb31a4 230 Pfam PF10411 Disulfide bond isomerase protein N-terminus 27 77 2.8E-13 T 29-03-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal MC49_RS18400 8151a5452d18589292f0bde675cb31a4 230 Pfam PF13098 Thioredoxin-like domain 105 227 2.0E-24 T 29-03-2018 IPR012336 Thioredoxin-like fold MC49_RS18400 8151a5452d18589292f0bde675cb31a4 230 Gene3D G3DSA:3.10.450.70 19 79 2.0E-17 T 29-03-2018 MC49_RS18400 8151a5452d18589292f0bde675cb31a4 230 SUPERFAMILY SSF54423 24 79 9.94E-15 T 29-03-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal MC49_RS09510 5c729a5e086535139d8b82fee7dcd7be 296 Pfam PF00701 Dihydrodipicolinate synthetase family 4 289 4.0E-42 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MC49_RS09510 5c729a5e086535139d8b82fee7dcd7be 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 37 58 8.4E-7 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MC49_RS09510 5c729a5e086535139d8b82fee7dcd7be 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 73 91 8.4E-7 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MC49_RS09510 5c729a5e086535139d8b82fee7dcd7be 296 Gene3D G3DSA:3.20.20.70 1 296 9.9E-69 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS09510 5c729a5e086535139d8b82fee7dcd7be 296 SMART SM01130 3 294 6.0E-58 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MC49_RS09510 5c729a5e086535139d8b82fee7dcd7be 296 PIRSF PIRSF001365 1 296 1.7E-60 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 MC49_RS09510 5c729a5e086535139d8b82fee7dcd7be 296 SUPERFAMILY SSF51569 1 295 1.05E-68 T 29-03-2018 MC49_RS10285 0a5e2030b612009f4d6478bfc00e6be6 555 SUPERFAMILY SSF52374 10 337 5.07E-103 T 29-03-2018 MC49_RS10285 0a5e2030b612009f4d6478bfc00e6be6 555 Gene3D G3DSA:3.40.50.620 8 41 0.0056 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS10285 0a5e2030b612009f4d6478bfc00e6be6 555 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 1 549 53.353 T 29-03-2018 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 MC49_RS10285 0a5e2030b612009f4d6478bfc00e6be6 555 PRINTS PR00987 Glutamyl-tRNA synthetase signature 60 73 2.4E-9 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 MC49_RS10285 0a5e2030b612009f4d6478bfc00e6be6 555 PRINTS PR00987 Glutamyl-tRNA synthetase signature 45 56 2.4E-9 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 MC49_RS10285 0a5e2030b612009f4d6478bfc00e6be6 555 PRINTS PR00987 Glutamyl-tRNA synthetase signature 31 43 2.4E-9 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 MC49_RS10285 0a5e2030b612009f4d6478bfc00e6be6 555 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 220 2.4E-9 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 MC49_RS10285 0a5e2030b612009f4d6478bfc00e6be6 555 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 28 337 5.3E-127 T 29-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 MC49_RS10285 0a5e2030b612009f4d6478bfc00e6be6 555 SUPERFAMILY SSF50715 340 547 8.89E-80 T 29-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MC49_RS10285 0a5e2030b612009f4d6478bfc00e6be6 555 Gene3D G3DSA:3.40.50.620 156 260 1.2E-21 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS10285 0a5e2030b612009f4d6478bfc00e6be6 555 Gene3D G3DSA:3.40.50.620 42 152 5.5E-40 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS10285 0a5e2030b612009f4d6478bfc00e6be6 555 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 340 528 2.8E-61 T 29-03-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MC49_RS10285 0a5e2030b612009f4d6478bfc00e6be6 555 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 34 45 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS10285 0a5e2030b612009f4d6478bfc00e6be6 555 Gene3D G3DSA:2.40.240.10 464 547 2.5E-33 T 29-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MC49_RS10285 0a5e2030b612009f4d6478bfc00e6be6 555 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 28 551 4.4E-303 T 29-03-2018 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MC49_RS10285 0a5e2030b612009f4d6478bfc00e6be6 555 Gene3D G3DSA:1.10.1160.10 261 338 1.1E-35 T 29-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 MC49_RS10285 0a5e2030b612009f4d6478bfc00e6be6 555 Gene3D G3DSA:2.40.240.10 344 463 9.7E-48 T 29-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MC49_RS06215 2d0c290f97716b5a724aa234a47b3cc3 89 ProDom PD029038 YIHD CYTOPLASMIC ENZYME Y3814 GLYCOGEN YPO0013A HI0845 DIRECT ORF1 UNCHARACTERIZED 1 87 3.0E-37 T 29-03-2018 IPR009383 Protein of unknown function DUF1040 MC49_RS06215 2d0c290f97716b5a724aa234a47b3cc3 89 Pfam PF06288 Protein of unknown function (DUF1040) 1 86 7.1E-46 T 29-03-2018 IPR009383 Protein of unknown function DUF1040 MC49_RS16510 fae964c399fe5e93ebca8766c3c45c91 910 SUPERFAMILY SSF53706 222 691 3.93E-83 T 29-03-2018 MC49_RS16510 fae964c399fe5e93ebca8766c3c45c91 910 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 7 658 1.9E-202 T 29-03-2018 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16510 fae964c399fe5e93ebca8766c3c45c91 910 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 5 81 9.6E-12 T 29-03-2018 MC49_RS16510 fae964c399fe5e93ebca8766c3c45c91 910 Gene3D G3DSA:3.40.50.740 281 696 2.1E-28 T 29-03-2018 MC49_RS16510 fae964c399fe5e93ebca8766c3c45c91 910 Gene3D G3DSA:2.20.25.90 239 279 4.2E-11 T 29-03-2018 MC49_RS16510 fae964c399fe5e93ebca8766c3c45c91 910 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 224 277 1.2E-11 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16510 fae964c399fe5e93ebca8766c3c45c91 910 SUPERFAMILY SSF54862 84 216 2.26E-33 T 29-03-2018 MC49_RS16510 fae964c399fe5e93ebca8766c3c45c91 910 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 106 118 - T 29-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16510 fae964c399fe5e93ebca8766c3c45c91 910 SUPERFAMILY SSF50692 813 894 2.06E-10 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain MC49_RS16510 fae964c399fe5e93ebca8766c3c45c91 910 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 91 126 1.4E-14 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16510 fae964c399fe5e93ebca8766c3c45c91 910 Pfam PF01568 Molydopterin dinucleotide binding domain 832 904 7.3E-6 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 MC49_RS16510 fae964c399fe5e93ebca8766c3c45c91 910 Gene3D G3DSA:3.10.20.30 1 156 1.4E-10 T 29-03-2018 IPR012675 Beta-grasp domain MC49_RS16510 fae964c399fe5e93ebca8766c3c45c91 910 SMART SM00926 224 278 2.2E-11 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16510 fae964c399fe5e93ebca8766c3c45c91 910 SUPERFAMILY SSF54292 4 80 2.42E-18 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MC49_RS16510 fae964c399fe5e93ebca8766c3c45c91 910 Gene3D G3DSA:3.30.70.20 157 238 6.1E-4 T 29-03-2018 MC49_RS16510 fae964c399fe5e93ebca8766c3c45c91 910 Gene3D G3DSA:2.40.40.20 827 909 4.6E-10 T 29-03-2018 MC49_RS16510 fae964c399fe5e93ebca8766c3c45c91 910 SMART SM00929 91 131 8.7E-19 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16510 fae964c399fe5e93ebca8766c3c45c91 910 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 34 51 - T 29-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16510 fae964c399fe5e93ebca8766c3c45c91 910 Pfam PF00384 Molybdopterin oxidoreductase 344 645 1.3E-8 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16510 fae964c399fe5e93ebca8766c3c45c91 910 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 153 163 - T 29-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS01150 ab4b2b779cc0ed7298dcabfe60365367 191 Gene3D G3DSA:2.10.109.10 36 191 3.5E-12 T 29-03-2018 MC49_RS01150 ab4b2b779cc0ed7298dcabfe60365367 191 Pfam PF10502 Signal peptidase, peptidase S26 50 187 5.2E-55 T 29-03-2018 IPR019533 Peptidase S26 MC49_RS01150 ab4b2b779cc0ed7298dcabfe60365367 191 SUPERFAMILY SSF51306 52 186 1.36E-24 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MC49_RS05655 7060758200ad11e681df9cfede393345 337 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 4 324 38.206 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MC49_RS05655 7060758200ad11e681df9cfede393345 337 SUPERFAMILY SSF51735 6 180 5.83E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS05655 7060758200ad11e681df9cfede393345 337 SUPERFAMILY SSF48179 182 333 3.4E-58 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MC49_RS05655 7060758200ad11e681df9cfede393345 337 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 190 211 - T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MC49_RS05655 7060758200ad11e681df9cfede393345 337 Gene3D G3DSA:3.40.50.720 1 179 6.0E-38 T 29-03-2018 MC49_RS05655 7060758200ad11e681df9cfede393345 337 Gene3D G3DSA:1.10.1040.10 191 337 1.3E-54 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MC49_RS05655 7060758200ad11e681df9cfede393345 337 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 134 154 2.7E-40 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MC49_RS05655 7060758200ad11e681df9cfede393345 337 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 175 199 2.7E-40 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MC49_RS05655 7060758200ad11e681df9cfede393345 337 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 240 257 2.7E-40 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MC49_RS05655 7060758200ad11e681df9cfede393345 337 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 200 224 2.7E-40 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MC49_RS05655 7060758200ad11e681df9cfede393345 337 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 58 85 2.7E-40 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MC49_RS05655 7060758200ad11e681df9cfede393345 337 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 8 25 2.7E-40 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MC49_RS05655 7060758200ad11e681df9cfede393345 337 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 6 161 2.9E-48 T 29-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MC49_RS05655 7060758200ad11e681df9cfede393345 337 PIRSF PIRSF000114 2 334 6.6E-101 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MC49_RS05655 7060758200ad11e681df9cfede393345 337 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 182 321 3.7E-53 T 29-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 MC49_RS07220 c4e3b80f9ca485c76d9e1e3deb8152ea 147 Pfam PF05232 Chlorhexidine efflux transporter 3 65 2.2E-15 T 29-03-2018 IPR007896 Chlorhexidine efflux transporter MC49_RS07220 c4e3b80f9ca485c76d9e1e3deb8152ea 147 Pfam PF05232 Chlorhexidine efflux transporter 71 133 2.2E-22 T 29-03-2018 IPR007896 Chlorhexidine efflux transporter MC49_RS01895 22f577dac9951f7556b471ba5a9779ed 84 Hamap MF_00413 Sulfurtransferase TusA [tusA]. 3 81 29.036 T 29-03-2018 IPR022931 Sulfur carrier protein TusA GO:0002143|GO:0097163 MC49_RS01895 22f577dac9951f7556b471ba5a9779ed 84 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 12 36 - T 29-03-2018 IPR001455 TusA-like domain MC49_RS01895 22f577dac9951f7556b471ba5a9779ed 84 SUPERFAMILY SSF64307 8 79 2.62E-26 T 29-03-2018 IPR001455 TusA-like domain MC49_RS01895 22f577dac9951f7556b471ba5a9779ed 84 Pfam PF01206 Sulfurtransferase TusA 10 79 3.0E-25 T 29-03-2018 IPR001455 TusA-like domain MC49_RS01895 22f577dac9951f7556b471ba5a9779ed 84 Gene3D G3DSA:3.30.110.40 6 81 6.5E-29 T 29-03-2018 IPR001455 TusA-like domain MC49_RS12490 3a706abd155ddaec0722f371c28fb7d5 1413 Pfam PF12255 Insecticide toxin TcdB middle/C-terminal region 858 1003 4.6E-46 T 29-03-2018 IPR022044 Insecticide toxin TcdB middle/C-terminal MC49_RS12490 3a706abd155ddaec0722f371c28fb7d5 1413 Pfam PF03534 Salmonella virulence plasmid 65kDa B protein 32 313 1.2E-88 T 29-03-2018 IPR003284 Salmonella virulence plasmid 65kDa B protein GO:0005737 MC49_RS12490 3a706abd155ddaec0722f371c28fb7d5 1413 Pfam PF12256 Insecticide toxin TcdB middle/N-terminal region 640 809 5.5E-31 T 29-03-2018 IPR022045 Insecticide toxin TcdB middle/N-terminal MC49_RS12490 3a706abd155ddaec0722f371c28fb7d5 1413 Gene3D G3DSA:2.130.10.130 567 681 4.8E-5 T 29-03-2018 MC49_RS12490 3a706abd155ddaec0722f371c28fb7d5 1413 Gene3D G3DSA:2.130.10.130 407 566 4.7E-7 T 29-03-2018 MC49_RS12490 3a706abd155ddaec0722f371c28fb7d5 1413 SUPERFAMILY SSF69318 435 660 5.62E-15 T 29-03-2018 MC49_RS12490 3a706abd155ddaec0722f371c28fb7d5 1413 PRINTS PR01341 Salmonella virulence plasmid 65kDa B protein signature 88 104 3.7E-33 T 29-03-2018 IPR003284 Salmonella virulence plasmid 65kDa B protein GO:0005737 MC49_RS12490 3a706abd155ddaec0722f371c28fb7d5 1413 PRINTS PR01341 Salmonella virulence plasmid 65kDa B protein signature 185 203 3.7E-33 T 29-03-2018 IPR003284 Salmonella virulence plasmid 65kDa B protein GO:0005737 MC49_RS12490 3a706abd155ddaec0722f371c28fb7d5 1413 PRINTS PR01341 Salmonella virulence plasmid 65kDa B protein signature 29 50 3.7E-33 T 29-03-2018 IPR003284 Salmonella virulence plasmid 65kDa B protein GO:0005737 MC49_RS12490 3a706abd155ddaec0722f371c28fb7d5 1413 PRINTS PR01341 Salmonella virulence plasmid 65kDa B protein signature 294 312 3.7E-33 T 29-03-2018 IPR003284 Salmonella virulence plasmid 65kDa B protein GO:0005737 MC49_RS12490 3a706abd155ddaec0722f371c28fb7d5 1413 PRINTS PR01341 Salmonella virulence plasmid 65kDa B protein signature 261 280 3.7E-33 T 29-03-2018 IPR003284 Salmonella virulence plasmid 65kDa B protein GO:0005737 MC49_RS15555 7357f5feffde123d6f2f2e7cfd82df54 327 Gene3D G3DSA:3.30.460.20 1 139 4.3E-16 T 29-03-2018 MC49_RS15555 7357f5feffde123d6f2f2e7cfd82df54 327 Gene3D G3DSA:1.20.58.340 140 260 1.3E-19 T 29-03-2018 MC49_RS15555 7357f5feffde123d6f2f2e7cfd82df54 327 Gene3D G3DSA:1.20.58.340 261 327 3.3E-14 T 29-03-2018 MC49_RS15555 7357f5feffde123d6f2f2e7cfd82df54 327 Pfam PF01544 CorA-like Mg2+ transporter protein 40 323 2.4E-59 T 29-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 MC49_RS15555 7357f5feffde123d6f2f2e7cfd82df54 327 SUPERFAMILY SSF144083 263 324 3.79E-13 T 29-03-2018 MC49_RS15555 7357f5feffde123d6f2f2e7cfd82df54 327 SUPERFAMILY SSF143865 14 259 4.05E-48 T 29-03-2018 MC49_RS04215 d0a749abe9ed1fd4984af9f3c478092d 345 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 210 332 7.9E-35 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MC49_RS04215 d0a749abe9ed1fd4984af9f3c478092d 345 Gene3D G3DSA:3.90.78.10 225 337 1.6E-40 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MC49_RS04215 d0a749abe9ed1fd4984af9f3c478092d 345 SUPERFAMILY SSF56194 206 342 3.14E-49 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MC49_RS04215 d0a749abe9ed1fd4984af9f3c478092d 345 SUPERFAMILY SSF56176 9 201 1.78E-43 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 MC49_RS04215 d0a749abe9ed1fd4984af9f3c478092d 345 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 9 333 3.6E-105 T 29-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MC49_RS04215 d0a749abe9ed1fd4984af9f3c478092d 345 Gene3D G3DSA:3.30.43.10 1 71 2.9E-16 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 MC49_RS04215 d0a749abe9ed1fd4984af9f3c478092d 345 Gene3D G3DSA:3.30.465.10 73 222 9.9E-48 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 MC49_RS04215 d0a749abe9ed1fd4984af9f3c478092d 345 Pfam PF01565 FAD binding domain 26 153 8.2E-20 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MC49_RS04215 d0a749abe9ed1fd4984af9f3c478092d 345 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 345 86.787 T 29-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MC49_RS16675 da2f9f7209105321e69178b08a393b3d 701 Gene3D G3DSA:3.50.50.60 280 701 1.3E-60 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS16675 da2f9f7209105321e69178b08a393b3d 701 TIGRFAM TIGR03197 MnmC_Cterm: tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain 292 694 1.2E-147 T 29-03-2018 IPR017610 tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal GO:0008168|GO:0016645|GO:0055114 MC49_RS16675 da2f9f7209105321e69178b08a393b3d 701 Gene3D G3DSA:3.40.50.150 35 279 8.1E-84 T 29-03-2018 MC49_RS16675 da2f9f7209105321e69178b08a393b3d 701 Pfam PF01266 FAD dependent oxidoreductase 292 664 5.4E-48 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MC49_RS16675 da2f9f7209105321e69178b08a393b3d 701 Hamap MF_01102 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC [mnmC]. 33 689 27.828 T 29-03-2018 IPR023032 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC GO:0004808|GO:0008033|GO:0008168|GO:0016645|GO:0055114 MC49_RS16675 da2f9f7209105321e69178b08a393b3d 701 Pfam PF05430 S-adenosyl-L-methionine-dependent methyltransferase 145 270 2.1E-46 T 29-03-2018 IPR008471 MnmC-like methyltransferase GO:0016645|GO:0055114 MC49_RS16675 da2f9f7209105321e69178b08a393b3d 701 SUPERFAMILY SSF51905 292 507 1.88E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS16675 da2f9f7209105321e69178b08a393b3d 701 SUPERFAMILY SSF51905 638 692 1.88E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS16675 da2f9f7209105321e69178b08a393b3d 701 SUPERFAMILY SSF51905 600 611 1.88E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS16675 da2f9f7209105321e69178b08a393b3d 701 SUPERFAMILY SSF54373 505 587 9.42E-5 T 29-03-2018 MC49_RS03010 a472f803f02fb5ac3a44efd1fb09fccc 175 Gene3D G3DSA:2.60.40.1090 16 175 3.6E-26 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS03010 a472f803f02fb5ac3a44efd1fb09fccc 175 Pfam PF00419 Fimbrial protein 19 175 9.5E-15 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS03010 a472f803f02fb5ac3a44efd1fb09fccc 175 SUPERFAMILY SSF49401 17 175 5.97E-28 T 29-03-2018 IPR008966 Adhesion domain MC49_RS10760 3db2f10bb00f8155150b481eb395fdf2 383 Pfam PF04235 Protein of unknown function (DUF418) 222 377 7.2E-33 T 29-03-2018 IPR007349 Domain of unknown function DUF418 MC49_RS18100 2e79c9b58d33a16416872e3f2f744320 422 TIGRFAM TIGR00837 araaP: aromatic amino acid transport protein 17 403 5.7E-138 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS18100 2e79c9b58d33a16416872e3f2f744320 422 PRINTS PR00166 Aromatic amino acid permease signature 333 351 3.6E-93 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS18100 2e79c9b58d33a16416872e3f2f744320 422 PRINTS PR00166 Aromatic amino acid permease signature 299 318 3.6E-93 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS18100 2e79c9b58d33a16416872e3f2f744320 422 PRINTS PR00166 Aromatic amino acid permease signature 354 373 3.6E-93 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS18100 2e79c9b58d33a16416872e3f2f744320 422 PRINTS PR00166 Aromatic amino acid permease signature 19 42 3.6E-93 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS18100 2e79c9b58d33a16416872e3f2f744320 422 PRINTS PR00166 Aromatic amino acid permease signature 46 65 3.6E-93 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS18100 2e79c9b58d33a16416872e3f2f744320 422 PRINTS PR00166 Aromatic amino acid permease signature 198 220 3.6E-93 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS18100 2e79c9b58d33a16416872e3f2f744320 422 PRINTS PR00166 Aromatic amino acid permease signature 238 257 3.6E-93 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS18100 2e79c9b58d33a16416872e3f2f744320 422 PRINTS PR00166 Aromatic amino acid permease signature 91 111 3.6E-93 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS18100 2e79c9b58d33a16416872e3f2f744320 422 PRINTS PR00166 Aromatic amino acid permease signature 157 177 3.6E-93 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS18100 2e79c9b58d33a16416872e3f2f744320 422 Pfam PF03222 Tryptophan/tyrosine permease family 10 409 2.1E-131 T 29-03-2018 IPR018227 Amino acid/polyamine transporter 2 GO:0003333 MC49_RS14130 767f5ae0246db35789281e63933b26a5 397 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 9 82 1.0E-8 T 29-03-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 MC49_RS14130 767f5ae0246db35789281e63933b26a5 397 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 195 393 5.5E-52 T 29-03-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 MC49_RS15160 433cd76db66462da0b8995dcb513c1b7 332 Pfam PF00591 Glycosyl transferase family, a/b domain 73 321 3.5E-91 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MC49_RS15160 433cd76db66462da0b8995dcb513c1b7 332 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 3 331 37.578 T 29-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 MC49_RS15160 433cd76db66462da0b8995dcb513c1b7 332 SUPERFAMILY SSF47648 1 67 1.44E-16 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 MC49_RS15160 433cd76db66462da0b8995dcb513c1b7 332 Gene3D G3DSA:1.20.970.10 1 67 1.4E-16 T 29-03-2018 MC49_RS15160 433cd76db66462da0b8995dcb513c1b7 332 SUPERFAMILY SSF52418 70 328 3.14E-86 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MC49_RS15160 433cd76db66462da0b8995dcb513c1b7 332 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 63 1.8E-15 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 MC49_RS15160 433cd76db66462da0b8995dcb513c1b7 332 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 6 329 2.3E-121 T 29-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 MC49_RS15160 433cd76db66462da0b8995dcb513c1b7 332 Gene3D G3DSA:3.40.1030.10 69 331 6.3E-88 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MC49_RS00615 d883c92d779cd374bdfdeea58787b805 643 Pfam PF13177 DNA polymerase III, delta subunit 20 178 7.1E-44 T 29-03-2018 MC49_RS00615 d883c92d779cd374bdfdeea58787b805 643 Pfam PF12168 DNA polymerase III subunits tau domain IV DnaB-binding 419 497 3.0E-11 T 29-03-2018 IPR022001 DNA polymerase III subunit tau, DnaB-binding domain IV KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS00615 d883c92d779cd374bdfdeea58787b805 643 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 232 362 4.1E-32 T 29-03-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 MC49_RS00615 d883c92d779cd374bdfdeea58787b805 643 Pfam PF12170 DNA polymerase III tau subunit V interacting with alpha 499 640 5.2E-57 T 29-03-2018 IPR021029 DNA polymerase III, tau subunit, domain V GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS00615 d883c92d779cd374bdfdeea58787b805 643 SUPERFAMILY SSF48019 243 366 2.89E-32 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 MC49_RS00615 d883c92d779cd374bdfdeea58787b805 643 SMART SM00382 37 178 9.5E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS00615 d883c92d779cd374bdfdeea58787b805 643 Gene3D G3DSA:1.10.8.60 167 242 1.3E-18 T 29-03-2018 MC49_RS00615 d883c92d779cd374bdfdeea58787b805 643 SUPERFAMILY SSF52540 34 223 1.69E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS00615 d883c92d779cd374bdfdeea58787b805 643 Gene3D G3DSA:1.20.272.10 243 362 2.3E-13 T 29-03-2018 MC49_RS00615 d883c92d779cd374bdfdeea58787b805 643 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 355 1.8E-131 T 29-03-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 MC49_RS00615 d883c92d779cd374bdfdeea58787b805 643 Gene3D G3DSA:3.40.50.300 1 166 2.2E-39 T 29-03-2018 MC49_RS00615 d883c92d779cd374bdfdeea58787b805 643 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 41 59 6.5E-5 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 MC49_RS00615 d883c92d779cd374bdfdeea58787b805 643 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 124 142 6.5E-5 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 MC49_RS15575 50e2f728d6382cd9ea62dd1a8417ad58 356 Pfam PF05128 Domain of unknown function (DUF697) 183 343 4.1E-56 T 29-03-2018 IPR021147 Protein of unknown function DUF697 MC49_RS15575 50e2f728d6382cd9ea62dd1a8417ad58 356 TIGRFAM TIGR01620 hyp_HI0043: TIGR01620 family protein 57 342 6.8E-119 T 29-03-2018 IPR006507 Uncharacterised protein family UPF0283 MC49_RS15575 50e2f728d6382cd9ea62dd1a8417ad58 356 Hamap MF_01085 UPF0283 membrane protein YcjF [ycjF]. 19 348 37.08 T 29-03-2018 IPR006507 Uncharacterised protein family UPF0283 MC49_RS02465 d93fb7f93294c9141448f5674df80b2e 316 ProSitePatterns PS01247 Inosine-uridine preferring nucleoside hydrolase family signature. 8 18 - T 29-03-2018 IPR015910 Inosine/uridine-preferring nucleoside hydrolase, conserved site GO:0016799 MC49_RS02465 d93fb7f93294c9141448f5674df80b2e 316 Gene3D G3DSA:3.90.245.10 1 310 3.1E-114 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain MC49_RS02465 d93fb7f93294c9141448f5674df80b2e 316 SUPERFAMILY SSF53590 2 311 1.11E-105 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain MC49_RS02465 d93fb7f93294c9141448f5674df80b2e 316 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 3 301 7.3E-94 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain MC49_RS14075 15f7a6789847bb7a13b5da4568f38906 261 Pfam PF00950 ABC 3 transport family 1 257 1.2E-84 T 29-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 MC49_RS14075 15f7a6789847bb7a13b5da4568f38906 261 SUPERFAMILY SSF81345 3 255 5.62E-40 T 29-03-2018 IPR029022 ABC transporter, BtuC-like MC49_RS14075 15f7a6789847bb7a13b5da4568f38906 261 Gene3D G3DSA:1.10.3470.10 1 261 1.2E-28 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like MC49_RS10730 f322bbeeb1df22d579e8bdc52696b9c8 434 SUPERFAMILY SSF51338 7 62 6.48E-6 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS10730 f322bbeeb1df22d579e8bdc52696b9c8 434 SUPERFAMILY SSF51556 56 374 5.83E-104 T 29-03-2018 IPR032466 Metal-dependent hydrolase MC49_RS10730 f322bbeeb1df22d579e8bdc52696b9c8 434 Gene3D G3DSA:3.20.20.140 69 364 8.8E-45 T 29-03-2018 MC49_RS10730 f322bbeeb1df22d579e8bdc52696b9c8 434 Gene3D G3DSA:2.30.40.10 9 68 8.9E-5 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS10730 f322bbeeb1df22d579e8bdc52696b9c8 434 Pfam PF07969 Amidohydrolase family 46 404 2.8E-56 T 29-03-2018 IPR013108 Amidohydrolase 3 MC49_RS08135 f8f8da12fabe107e1623a8eabf91bbe0 235 SUPERFAMILY SSF118196 1 230 3.79E-83 T 29-03-2018 IPR023370 TsaA-like domain MC49_RS08135 f8f8da12fabe107e1623a8eabf91bbe0 235 Pfam PF01980 Uncharacterised protein family UPF0066 21 142 2.0E-39 T 29-03-2018 IPR023370 TsaA-like domain MC49_RS08135 f8f8da12fabe107e1623a8eabf91bbe0 235 ProSitePatterns PS01318 TsaA-like domain signature. 87 98 - T 29-03-2018 IPR023368 Uncharacterised protein family UPF0066, conserved site MC49_RS08135 f8f8da12fabe107e1623a8eabf91bbe0 235 Gene3D G3DSA:2.40.30.70 5 149 2.5E-50 T 29-03-2018 IPR023370 TsaA-like domain MC49_RS08135 f8f8da12fabe107e1623a8eabf91bbe0 235 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 1 147 1.3E-51 T 29-03-2018 IPR023370 TsaA-like domain MC49_RS08135 f8f8da12fabe107e1623a8eabf91bbe0 235 Gene3D G3DSA:3.30.2310.10 150 231 2.4E-24 T 29-03-2018 MC49_RS05500 36101fb6adc07fa85e4c7ee5f94e1adf 466 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 19 445 5.9E-126 T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 MC49_RS05500 36101fb6adc07fa85e4c7ee5f94e1adf 466 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 363 383 - T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 MC49_RS05500 36101fb6adc07fa85e4c7ee5f94e1adf 466 Pfam PF00860 Permease family 23 414 4.1E-97 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 MC49_RS18520 f99d50d0674427a8fafd738de88fefd5 123 PIRSF PIRSF006287 1 120 2.6E-44 T 29-03-2018 IPR008249 Uncharacterised protein family UPF0231 MC49_RS18520 f99d50d0674427a8fafd738de88fefd5 123 Pfam PF06062 Uncharacterised protein family (UPF0231) 1 117 1.6E-41 T 29-03-2018 IPR008249 Uncharacterised protein family UPF0231 MC49_RS18520 f99d50d0674427a8fafd738de88fefd5 123 ProDom PD020773 UPF0231 YACL UNCHARACTERISED UCP006287 VC0605 UNCHARACTERIZED 3'REGION VV2750 BCR OXIDASE 1 117 3.0E-42 T 29-03-2018 IPR008249 Uncharacterised protein family UPF0231 MC49_RS18520 f99d50d0674427a8fafd738de88fefd5 123 Hamap MF_01053 UPF0231 protein YacL [yacL]. 1 119 27.349 T 29-03-2018 IPR008249 Uncharacterised protein family UPF0231 MC49_RS08530 5a2f731c1691ccbc403d85f5628a349c 324 Gene3D G3DSA:3.20.20.150 2 319 6.3E-25 T 29-03-2018 MC49_RS08530 5a2f731c1691ccbc403d85f5628a349c 324 SUPERFAMILY SSF51658 38 245 4.84E-20 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MC49_RS08530 5a2f731c1691ccbc403d85f5628a349c 324 Pfam PF01261 Xylose isomerase-like TIM barrel 57 215 1.0E-10 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MC49_RS01725 7dea5de511b236d1a0a54a01b9fa5446 458 PRINTS PR01036 Tetracycline resistance protein TetB signature 96 116 1.3E-7 T 29-03-2018 MC49_RS01725 7dea5de511b236d1a0a54a01b9fa5446 458 PRINTS PR01036 Tetracycline resistance protein TetB signature 126 150 1.3E-7 T 29-03-2018 MC49_RS01725 7dea5de511b236d1a0a54a01b9fa5446 458 PRINTS PR01036 Tetracycline resistance protein TetB signature 5 29 1.3E-7 T 29-03-2018 MC49_RS01725 7dea5de511b236d1a0a54a01b9fa5446 458 PRINTS PR01036 Tetracycline resistance protein TetB signature 290 314 1.3E-7 T 29-03-2018 MC49_RS01725 7dea5de511b236d1a0a54a01b9fa5446 458 Gene3D G3DSA:1.20.1250.20 1 174 5.5E-23 T 29-03-2018 MC49_RS01725 7dea5de511b236d1a0a54a01b9fa5446 458 Gene3D G3DSA:1.20.1250.20 248 458 1.3E-27 T 29-03-2018 MC49_RS01725 7dea5de511b236d1a0a54a01b9fa5446 458 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 2 415 1.9E-76 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 MC49_RS01725 7dea5de511b236d1a0a54a01b9fa5446 458 Pfam PF07690 Major Facilitator Superfamily 7 398 6.5E-40 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS01725 7dea5de511b236d1a0a54a01b9fa5446 458 SUPERFAMILY SSF103473 3 180 2.09E-55 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS01725 7dea5de511b236d1a0a54a01b9fa5446 458 SUPERFAMILY SSF103473 236 452 2.09E-55 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS06250 cee0ce5933eae191d62db97dcb70434d 207 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 12 197 6.1E-73 T 29-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 MC49_RS06250 cee0ce5933eae191d62db97dcb70434d 207 SUPERFAMILY SSF52540 19 201 6.74E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS06250 cee0ce5933eae191d62db97dcb70434d 207 Gene3D G3DSA:3.40.50.300 80 205 3.9E-14 T 29-03-2018 MC49_RS06250 cee0ce5933eae191d62db97dcb70434d 207 Pfam PF01926 50S ribosome-binding GTPase 30 148 2.9E-19 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 MC49_RS06250 cee0ce5933eae191d62db97dcb70434d 207 Gene3D G3DSA:3.40.50.300 16 79 3.6E-12 T 29-03-2018 MC49_RS06250 cee0ce5933eae191d62db97dcb70434d 207 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 16 201 27.369 T 29-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 MC49_RS07975 579671f5c1e5f076c1dea02cf33fee98 455 Gene3D G3DSA:3.30.1850.10 3 111 5.4E-48 T 29-03-2018 IPR027820 Domain of unknown function DUF4478 MC49_RS07975 579671f5c1e5f076c1dea02cf33fee98 455 Pfam PF03641 Possible lysine decarboxylase 190 329 2.2E-31 T 29-03-2018 IPR031100 LOG family MC49_RS07975 579671f5c1e5f076c1dea02cf33fee98 455 Pfam PF11892 Domain of unknown function (DUF3412) 333 454 1.0E-56 T 29-03-2018 IPR021826 Domain of unknown function DUF3412 MC49_RS07975 579671f5c1e5f076c1dea02cf33fee98 455 Pfam PF14793 Domain of unknown function (DUF4478) 4 111 1.2E-46 T 29-03-2018 IPR027820 Domain of unknown function DUF4478 MC49_RS07975 579671f5c1e5f076c1dea02cf33fee98 455 Gene3D G3DSA:3.40.50.450 124 453 4.8E-100 T 29-03-2018 MC49_RS07975 579671f5c1e5f076c1dea02cf33fee98 455 SUPERFAMILY SSF102405 121 330 7.48E-41 T 29-03-2018 MC49_RS08335 3b97ee65d8484dfd0041ea595ac78c36 552 Gene3D G3DSA:3.20.130.10 359 536 1.6E-61 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 MC49_RS08335 3b97ee65d8484dfd0041ea595ac78c36 552 ProSitePatterns PS00163 Fumarate lyases signature. 456 465 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 MC49_RS08335 3b97ee65d8484dfd0041ea595ac78c36 552 Pfam PF05683 Fumarase C-terminus 332 537 4.3E-86 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 MC49_RS08335 3b97ee65d8484dfd0041ea595ac78c36 552 Pfam PF05681 Fumarate hydratase (Fumerase) 51 325 4.5E-80 T 29-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 MC49_RS08335 3b97ee65d8484dfd0041ea595ac78c36 552 SUPERFAMILY SSF117457 361 536 2.88E-57 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 MC49_RS08335 3b97ee65d8484dfd0041ea595ac78c36 552 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 373 537 1.7E-54 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 MC49_RS08335 3b97ee65d8484dfd0041ea595ac78c36 552 PIRSF PIRSF001394 30 551 9.0E-219 T 29-03-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 MC49_RS17090 629a21d6d625a8d34631015a84be9ea1 78 Gene3D G3DSA:1.10.1200.10 1 78 2.2E-28 T 29-03-2018 MC49_RS17090 629a21d6d625a8d34631015a84be9ea1 78 SUPERFAMILY SSF47336 2 76 3.53E-24 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MC49_RS17090 629a21d6d625a8d34631015a84be9ea1 78 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site MC49_RS17090 629a21d6d625a8d34631015a84be9ea1 78 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 34 75 0.003 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 MC49_RS17090 629a21d6d625a8d34631015a84be9ea1 78 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 1 75 2.4E-37 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 MC49_RS17090 629a21d6d625a8d34631015a84be9ea1 78 Pfam PF00550 Phosphopantetheine attachment site 6 73 6.8E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain MC49_RS17090 629a21d6d625a8d34631015a84be9ea1 78 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 23.139 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 MC49_RS03890 0daef39d1e22ab12a18b7fbd851db5e5 616 SUPERFAMILY SSF52016 421 610 9.42E-59 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel MC49_RS03890 0daef39d1e22ab12a18b7fbd851db5e5 616 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MC49_RS03890 0daef39d1e22ab12a18b7fbd851db5e5 616 SUPERFAMILY SSF143975 4 420 3.4E-133 T 29-03-2018 MC49_RS03890 0daef39d1e22ab12a18b7fbd851db5e5 616 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 610 44.794 T 29-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MC49_RS03890 0daef39d1e22ab12a18b7fbd851db5e5 616 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 610 3.2E-262 T 29-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MC49_RS03890 0daef39d1e22ab12a18b7fbd851db5e5 616 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 509 520 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MC49_RS03890 0daef39d1e22ab12a18b7fbd851db5e5 616 Pfam PF00920 Dehydratase family 34 607 3.5E-217 T 29-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MC49_RS16895 77e20afa1603caabc4c337f4545a03af 118 Pfam PF04237 YjbR 14 116 5.3E-22 T 29-03-2018 IPR007351 Uncharacterised protein YjbR MC49_RS16895 77e20afa1603caabc4c337f4545a03af 118 SUPERFAMILY SSF142906 1 117 5.75E-34 T 29-03-2018 MC49_RS10580 a1f2c3966b895043d22c698f9d8b5a7f 390 SUPERFAMILY SSF53383 1 381 4.76E-105 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS10580 a1f2c3966b895043d22c698f9d8b5a7f 390 Gene3D G3DSA:3.40.640.10 72 284 8.6E-46 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS10580 a1f2c3966b895043d22c698f9d8b5a7f 390 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 19 379 1.2E-131 T 29-03-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 MC49_RS10580 a1f2c3966b895043d22c698f9d8b5a7f 390 Hamap MF_01693 8-amino-7-oxononanoate synthase [bioF]. 2 383 45.527 T 29-03-2018 IPR022834 8-amino-7-oxononanoate synthase, Proteobacteria GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 MC49_RS10580 a1f2c3966b895043d22c698f9d8b5a7f 390 Gene3D G3DSA:3.90.1150.10 285 386 8.9E-28 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS10580 a1f2c3966b895043d22c698f9d8b5a7f 390 Pfam PF00155 Aminotransferase class I and II 41 379 4.0E-53 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MC49_RS10580 a1f2c3966b895043d22c698f9d8b5a7f 390 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 234 243 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 MC49_RS11240 f1e43af57f0f29408471b8127e2fd0d4 872 Pfam PF11940 Domain of unknown function (DUF3458) Ig-like fold 443 543 1.4E-34 T 29-03-2018 IPR035414 Peptidase M1, alanyl aminopeptidase, Ig-like fold MC49_RS11240 f1e43af57f0f29408471b8127e2fd0d4 872 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 312 324 6.7E-8 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MC49_RS11240 f1e43af57f0f29408471b8127e2fd0d4 872 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 293 308 6.7E-8 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MC49_RS11240 f1e43af57f0f29408471b8127e2fd0d4 872 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 175 190 6.7E-8 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MC49_RS11240 f1e43af57f0f29408471b8127e2fd0d4 872 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 257 267 6.7E-8 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MC49_RS11240 f1e43af57f0f29408471b8127e2fd0d4 872 SUPERFAMILY SSF55486 203 449 3.48E-75 T 29-03-2018 MC49_RS11240 f1e43af57f0f29408471b8127e2fd0d4 872 Gene3D G3DSA:1.10.390.10 279 442 6.1E-51 T 29-03-2018 MC49_RS11240 f1e43af57f0f29408471b8127e2fd0d4 872 Gene3D G3DSA:2.60.40.1730 15 193 1.2E-30 T 29-03-2018 MC49_RS11240 f1e43af57f0f29408471b8127e2fd0d4 872 SUPERFAMILY SSF63737 1 192 3.79E-46 T 29-03-2018 MC49_RS11240 f1e43af57f0f29408471b8127e2fd0d4 872 Pfam PF17432 Domain of unknown function (DUF3458_C) ARM repeats 547 869 4.6E-119 T 29-03-2018 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal MC49_RS11240 f1e43af57f0f29408471b8127e2fd0d4 872 Gene3D G3DSA:1.25.50.10 545 870 1.1E-121 T 29-03-2018 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal MC49_RS11240 f1e43af57f0f29408471b8127e2fd0d4 872 Pfam PF01433 Peptidase family M1 domain 207 438 2.3E-58 T 29-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MC49_RS11240 f1e43af57f0f29408471b8127e2fd0d4 872 TIGRFAM TIGR02414 pepN_proteo: aminopeptidase N 12 869 0.0 T 29-03-2018 IPR012779 Peptidase M1, alanyl aminopeptidase GO:0008270 MC49_RS10990 4e0b21b387876cb7a98688135daf8eb7 244 SMART SM00062 24 244 3.3E-80 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MC49_RS10990 4e0b21b387876cb7a98688135daf8eb7 244 Gene3D G3DSA:3.40.190.10 146 244 1.2E-20 T 29-03-2018 MC49_RS10990 4e0b21b387876cb7a98688135daf8eb7 244 SUPERFAMILY SSF53850 1 243 2.73E-72 T 29-03-2018 MC49_RS10990 4e0b21b387876cb7a98688135daf8eb7 244 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 47 60 - T 29-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 MC49_RS10990 4e0b21b387876cb7a98688135daf8eb7 244 TIGRFAM TIGR01096 3A0103s03R: lysine-arginine-ornithine-binding periplasmic protein 5 243 2.6E-86 T 29-03-2018 IPR005768 Specific amino acids and opine-binding periplasmic protein, ABC transporter GO:0006810|GO:0030288 MC49_RS10990 4e0b21b387876cb7a98688135daf8eb7 244 SMART SM00079 24 244 0.0018 T 29-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 MC49_RS10990 4e0b21b387876cb7a98688135daf8eb7 244 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 25 243 4.5E-68 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MC49_RS10990 4e0b21b387876cb7a98688135daf8eb7 244 Gene3D G3DSA:3.40.190.10 19 145 5.1E-35 T 29-03-2018 MC49_RS14145 46bc909082560730450ba01eeb82e4fe 458 SMART SM00388 238 304 2.7E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS14145 46bc909082560730450ba01eeb82e4fe 458 Pfam PF00512 His Kinase A (phospho-acceptor) domain 239 303 9.5E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS14145 46bc909082560730450ba01eeb82e4fe 458 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 349 453 2.2E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS14145 46bc909082560730450ba01eeb82e4fe 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 434 8.4E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS14145 46bc909082560730450ba01eeb82e4fe 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 411 8.4E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS14145 46bc909082560730450ba01eeb82e4fe 458 Gene3D G3DSA:3.30.565.10 308 456 3.8E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS14145 46bc909082560730450ba01eeb82e4fe 458 Gene3D G3DSA:1.10.287.130 228 300 1.1E-9 T 29-03-2018 MC49_RS14145 46bc909082560730450ba01eeb82e4fe 458 SUPERFAMILY SSF55874 294 452 3.93E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS14145 46bc909082560730450ba01eeb82e4fe 458 SMART SM00387 348 455 2.4E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS14145 46bc909082560730450ba01eeb82e4fe 458 SUPERFAMILY SSF47384 222 305 6.47E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS09910 5278a5444382111f405e1fcedeab70b5 325 Gene3D G3DSA:3.30.930.10 9 325 1.6E-69 T 29-03-2018 MC49_RS09910 5278a5444382111f405e1fcedeab70b5 325 Pfam PF00152 tRNA synthetases class II (D, K and N) 14 322 1.0E-47 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS09910 5278a5444382111f405e1fcedeab70b5 325 SUPERFAMILY SSF55681 13 323 9.16E-87 T 29-03-2018 MC49_RS09910 5278a5444382111f405e1fcedeab70b5 325 PRINTS PR00982 Lysyl-tRNA synthetase signature 99 116 1.7E-5 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MC49_RS09910 5278a5444382111f405e1fcedeab70b5 325 PRINTS PR00982 Lysyl-tRNA synthetase signature 31 41 1.7E-5 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MC49_RS09910 5278a5444382111f405e1fcedeab70b5 325 TIGRFAM TIGR00462 genX: EF-P lysine aminoacylase GenX 17 320 1.3E-132 T 29-03-2018 IPR004525 Elongation factor P--(R)-beta-lysine ligase GO:0004824|GO:0005524|GO:0005737|GO:0006430 MC49_RS09910 5278a5444382111f405e1fcedeab70b5 325 Hamap MF_00174 Elongation factor P--(R)-beta-lysine ligase [epmA]. 2 325 55.932 T 29-03-2018 IPR004525 Elongation factor P--(R)-beta-lysine ligase GO:0004824|GO:0005524|GO:0005737|GO:0006430 MC49_RS09345 2e8e8ad1da2d8a18feea57ccd54245b1 143 Pfam PF01047 MarR family 29 86 2.3E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MC49_RS09345 2e8e8ad1da2d8a18feea57ccd54245b1 143 TIGRFAM TIGR02337 HpaR: homoprotocatechuate degradation operon regulator, HpaR 4 132 4.4E-51 T 29-03-2018 IPR012712 Homoprotocatechuate degradation transcriptional regulator HpaR GO:0003677|GO:0010124|GO:0045892 MC49_RS09345 2e8e8ad1da2d8a18feea57ccd54245b1 143 SMART SM00347 22 122 8.9E-22 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MC49_RS09345 2e8e8ad1da2d8a18feea57ccd54245b1 143 SUPERFAMILY SSF46785 4 134 5.22E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS09345 2e8e8ad1da2d8a18feea57ccd54245b1 143 Gene3D G3DSA:1.10.10.10 1 133 5.8E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS05740 395635bdfed5946b46be2838298bc77e 357 SUPERFAMILY SSF51569 184 313 5.01E-80 T 29-03-2018 MC49_RS05740 395635bdfed5946b46be2838298bc77e 357 SUPERFAMILY SSF51569 2 157 5.01E-80 T 29-03-2018 MC49_RS05740 395635bdfed5946b46be2838298bc77e 357 TIGRFAM TIGR03569 NeuB_NnaB: N-acetylneuraminate synthase 2 353 2.3E-144 T 29-03-2018 IPR020007 N-acetylneuraminate synthase KEGG: 00520+2.5.1.101|KEGG: 00900+2.5.1.10|MetaCyc: PWY-5123|MetaCyc: PWY-6749|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7131|MetaCyc: PWY-7721|MetaCyc: PWY-7736 MC49_RS05740 395635bdfed5946b46be2838298bc77e 357 Gene3D G3DSA:3.90.1210.10 293 357 1.4E-19 T 29-03-2018 MC49_RS05740 395635bdfed5946b46be2838298bc77e 357 Gene3D G3DSA:3.20.20.70 1 289 6.5E-85 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS05740 395635bdfed5946b46be2838298bc77e 357 Pfam PF03102 NeuB family 22 289 3.7E-97 T 29-03-2018 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Reactome: R-HSA-4085001 MC49_RS05740 395635bdfed5946b46be2838298bc77e 357 SUPERFAMILY SSF51269 295 355 5.81E-15 T 29-03-2018 IPR006190 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal Reactome: R-HSA-4085001 MC49_RS02675 71f59918a941df85dfbb59723e1d6700 267 SUPERFAMILY SSF53850 29 267 2.14E-74 T 29-03-2018 MC49_RS02675 71f59918a941df85dfbb59723e1d6700 267 PIRSF PIRSF002854 1 267 1.2E-92 T 29-03-2018 IPR004872 Lipoprotein NlpA family MC49_RS02675 71f59918a941df85dfbb59723e1d6700 267 Pfam PF03180 NLPA lipoprotein 29 267 1.1E-83 T 29-03-2018 IPR004872 Lipoprotein NlpA family MC49_RS02675 71f59918a941df85dfbb59723e1d6700 267 Gene3D G3DSA:3.40.190.10 28 122 1.9E-18 T 29-03-2018 MC49_RS02675 71f59918a941df85dfbb59723e1d6700 267 Gene3D G3DSA:3.40.190.10 123 267 2.1E-45 T 29-03-2018 MC49_RS02675 71f59918a941df85dfbb59723e1d6700 267 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 14 267 7.9E-95 T 29-03-2018 IPR004872 Lipoprotein NlpA family MC49_RS07115 a2fa676760c4cb2832fbad20121ef07d 86 Pfam PF02416 mttA/Hcf106 family 5 55 7.4E-13 T 29-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 MC49_RS07115 a2fa676760c4cb2832fbad20121ef07d 86 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 85 22.731 T 29-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 MC49_RS07115 a2fa676760c4cb2832fbad20121ef07d 86 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 48 2.2E-20 T 29-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 MC49_RS03450 65d51c7e8bdb0586bb0dfca3fb3f6729 102 SUPERFAMILY SSF141091 1 101 5.62E-38 T 29-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS03450 65d51c7e8bdb0586bb0dfca3fb3f6729 102 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 1.3E-44 T 29-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS03450 65d51c7e8bdb0586bb0dfca3fb3f6729 102 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 102 24.471 T 29-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS03450 65d51c7e8bdb0586bb0dfca3fb3f6729 102 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 29-03-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS03450 65d51c7e8bdb0586bb0dfca3fb3f6729 102 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 101 1.6E-39 T 29-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS16725 a9e659868da2779a30a7f3678081010e 156 TIGRFAM TIGR00249 sixA: phosphohistidine phosphatase SixA 1 152 2.2E-47 T 29-03-2018 IPR004449 Phosphohistidine phosphatase SixA GO:0005737|GO:0006464|GO:0008969 MC49_RS16725 a9e659868da2779a30a7f3678081010e 156 Gene3D G3DSA:3.40.50.1240 1 155 3.9E-26 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MC49_RS16725 a9e659868da2779a30a7f3678081010e 156 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 73 1.6E-9 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MC49_RS16725 a9e659868da2779a30a7f3678081010e 156 SMART SM00855 2 115 7.2E-4 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MC49_RS16725 a9e659868da2779a30a7f3678081010e 156 SUPERFAMILY SSF53254 1 143 5.14E-22 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MC49_RS02720 e4daf8cef652ebeec46750422875243c 220 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 191 203 - T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MC49_RS02720 e4daf8cef652ebeec46750422875243c 220 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 49 68 3.9E-60 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MC49_RS02720 e4daf8cef652ebeec46750422875243c 220 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 188 213 3.9E-60 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MC49_RS02720 e4daf8cef652ebeec46750422875243c 220 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 29 49 3.9E-60 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MC49_RS02720 e4daf8cef652ebeec46750422875243c 220 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 143 163 3.9E-60 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MC49_RS02720 e4daf8cef652ebeec46750422875243c 220 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 164 185 3.9E-60 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MC49_RS02720 e4daf8cef652ebeec46750422875243c 220 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 10 29 3.9E-60 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MC49_RS02720 e4daf8cef652ebeec46750422875243c 220 Pfam PF00813 FliP family 12 210 3.3E-56 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MC49_RS02720 e4daf8cef652ebeec46750422875243c 220 TIGRFAM TIGR01102 yscR: type III secretion apparatus protein, YscR/HrcR family 10 210 3.3E-69 T 29-03-2018 IPR005773 Yop virulence translocation protein R GO:0015031|GO:0016021 MC49_RS02760 eb0ff545df6745ef66084200fa98a687 541 Pfam PF00263 Bacterial type II and III secretion system protein 347 507 2.8E-37 T 29-03-2018 IPR004846 Type II/III secretion system GO:0009306 MC49_RS02760 eb0ff545df6745ef66084200fa98a687 541 Pfam PF03958 Bacterial type II/III secretion system short domain 190 293 2.0E-8 T 29-03-2018 IPR005644 NolW-like MC49_RS02760 eb0ff545df6745ef66084200fa98a687 541 PRINTS PR01337 Type III secretion system outer membrane G protein family signature 394 409 1.7E-33 T 29-03-2018 IPR003522 Type III secretion system outer membrane pore YscC/HrcC GO:0009306 MC49_RS02760 eb0ff545df6745ef66084200fa98a687 541 PRINTS PR01337 Type III secretion system outer membrane G protein family signature 201 218 1.7E-33 T 29-03-2018 IPR003522 Type III secretion system outer membrane pore YscC/HrcC GO:0009306 MC49_RS02760 eb0ff545df6745ef66084200fa98a687 541 PRINTS PR01337 Type III secretion system outer membrane G protein family signature 486 505 1.7E-33 T 29-03-2018 IPR003522 Type III secretion system outer membrane pore YscC/HrcC GO:0009306 MC49_RS02760 eb0ff545df6745ef66084200fa98a687 541 PRINTS PR01337 Type III secretion system outer membrane G protein family signature 360 379 1.7E-33 T 29-03-2018 IPR003522 Type III secretion system outer membrane pore YscC/HrcC GO:0009306 MC49_RS02760 eb0ff545df6745ef66084200fa98a687 541 PRINTS PR01337 Type III secretion system outer membrane G protein family signature 295 315 1.7E-33 T 29-03-2018 IPR003522 Type III secretion system outer membrane pore YscC/HrcC GO:0009306 MC49_RS02760 eb0ff545df6745ef66084200fa98a687 541 TIGRFAM TIGR02516 type_III_yscC: type III secretion outer membrane pore, YscC/HrcC family 39 508 4.7E-125 T 29-03-2018 IPR003522 Type III secretion system outer membrane pore YscC/HrcC GO:0009306 MC49_RS02200 67e91e774070cd57f4b9912312316a9d 481 Gene3D G3DSA:1.20.5.1230 270 423 2.0E-4 T 29-03-2018 MC49_RS02200 67e91e774070cd57f4b9912312316a9d 481 SMART SM00990 75 202 6.9E-13 T 29-03-2018 IPR014883 VRR-NUC domain GO:0016788 Reactome: R-HSA-6783310 MC49_RS02200 67e91e774070cd57f4b9912312316a9d 481 Pfam PF08774 VRR-NUC domain 76 200 1.9E-13 T 29-03-2018 IPR014883 VRR-NUC domain GO:0016788 Reactome: R-HSA-6783310 MC49_RS12235 bb6605c4dd83c6643aa7781e30f9b3ba 197 ProDom PD105195 LIPOPROTEIN YFEY MEMBRANE OUTER PRECURSOR SIGNAL ESCHERICHIA ECS3303 EXPORTED Y1456 41 194 6.0E-37 T 29-03-2018 IPR010938 Protein of unknown function DUF1131 MC49_RS12235 bb6605c4dd83c6643aa7781e30f9b3ba 197 Pfam PF06572 Protein of unknown function (DUF1131) 24 195 6.0E-72 T 29-03-2018 IPR010938 Protein of unknown function DUF1131 MC49_RS12235 bb6605c4dd83c6643aa7781e30f9b3ba 197 Gene3D G3DSA:2.60.460.10 32 195 2.8E-53 T 29-03-2018 MC49_RS09185 2a0a06f339d94a3d422c9efed41d713c 262 TIGRFAM TIGR00444 mazG: MazG family protein 11 258 6.2E-101 T 29-03-2018 IPR011551 NTP pyrophosphohydrolase MazG MC49_RS09185 2a0a06f339d94a3d422c9efed41d713c 262 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 28 101 2.8E-27 T 29-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core MC49_RS09185 2a0a06f339d94a3d422c9efed41d713c 262 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 170 230 4.1E-10 T 29-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core MC49_RS09185 2a0a06f339d94a3d422c9efed41d713c 262 Gene3D G3DSA:1.10.287.1080 4 123 1.9E-37 T 29-03-2018 MC49_RS09185 2a0a06f339d94a3d422c9efed41d713c 262 SUPERFAMILY SSF101386 136 237 4.36E-25 T 29-03-2018 MC49_RS09185 2a0a06f339d94a3d422c9efed41d713c 262 SUPERFAMILY SSF101386 2 103 8.87E-25 T 29-03-2018 MC49_RS09185 2a0a06f339d94a3d422c9efed41d713c 262 Gene3D G3DSA:1.10.287.1080 138 262 1.8E-28 T 29-03-2018 MC49_RS12050 1d4a4dd1859d9dbf0914c1563d164410 479 Gene3D G3DSA:3.30.565.10 318 476 2.2E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS12050 1d4a4dd1859d9dbf0914c1563d164410 479 SMART SM00387 364 476 9.9E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS12050 1d4a4dd1859d9dbf0914c1563d164410 479 SUPERFAMILY SSF55874 325 474 7.6E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS12050 1d4a4dd1859d9dbf0914c1563d164410 479 SUPERFAMILY SSF47384 237 317 1.1E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS12050 1d4a4dd1859d9dbf0914c1563d164410 479 Pfam PF00512 His Kinase A (phospho-acceptor) domain 254 317 1.1E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS12050 1d4a4dd1859d9dbf0914c1563d164410 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 415 9.8E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS12050 1d4a4dd1859d9dbf0914c1563d164410 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 436 454 9.8E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS12050 1d4a4dd1859d9dbf0914c1563d164410 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 419 429 9.8E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS12050 1d4a4dd1859d9dbf0914c1563d164410 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 460 473 9.8E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS12050 1d4a4dd1859d9dbf0914c1563d164410 479 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 368 473 4.7E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS12050 1d4a4dd1859d9dbf0914c1563d164410 479 Gene3D G3DSA:1.10.287.130 243 317 4.1E-13 T 29-03-2018 MC49_RS12050 1d4a4dd1859d9dbf0914c1563d164410 479 SMART SM00388 253 321 5.8E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS06085 467936fa7eedf6cb8f8cc8a309d58e83 426 Gene3D G3DSA:2.130.10.10 2 230 1.6E-4 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MC49_RS06085 467936fa7eedf6cb8f8cc8a309d58e83 426 Gene3D G3DSA:2.130.10.10 274 425 2.8E-14 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MC49_RS06085 467936fa7eedf6cb8f8cc8a309d58e83 426 SUPERFAMILY SSF82171 244 257 7.45E-16 T 29-03-2018 MC49_RS06085 467936fa7eedf6cb8f8cc8a309d58e83 426 SUPERFAMILY SSF82171 284 424 7.45E-16 T 29-03-2018 MC49_RS06085 467936fa7eedf6cb8f8cc8a309d58e83 426 SUPERFAMILY SSF82171 137 196 7.45E-16 T 29-03-2018 MC49_RS06085 467936fa7eedf6cb8f8cc8a309d58e83 426 Pfam PF12566 Protein of unknown function (DUF3748) 65 185 7.9E-57 T 29-03-2018 IPR022223 Protein of unknown function DUF3748 MC49_RS03650 b337fbaf5713a619bf405444d65f42b2 310 Hamap MF_00662 Phosphatidylserine decarboxylase proenzyme [psd]. 9 286 48.731 T 29-03-2018 IPR033178 Phosphatidylserine decarboxylase, prokaryotic type 1 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 MC49_RS03650 b337fbaf5713a619bf405444d65f42b2 310 Pfam PF02666 Phosphatidylserine decarboxylase 62 283 1.8E-57 T 29-03-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 MC49_RS03650 b337fbaf5713a619bf405444d65f42b2 310 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 48 284 2.4E-90 T 29-03-2018 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 MC49_RS08695 9e2f9331824f31f001cdf7f0d646e083 441 Pfam PF01979 Amidohydrolase family 53 410 1.8E-47 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MC49_RS08695 9e2f9331824f31f001cdf7f0d646e083 441 Gene3D G3DSA:2.30.40.10 348 439 2.7E-7 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS08695 9e2f9331824f31f001cdf7f0d646e083 441 Gene3D G3DSA:2.30.40.10 1 65 4.6E-13 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS08695 9e2f9331824f31f001cdf7f0d646e083 441 TIGRFAM TIGR03314 Se_ssnA: putative selenium metabolism protein SsnA 2 438 3.9E-203 T 29-03-2018 IPR017700 Putative aminohydrolase SsnA MC49_RS08695 9e2f9331824f31f001cdf7f0d646e083 441 SUPERFAMILY SSF51556 56 352 1.08E-53 T 29-03-2018 IPR032466 Metal-dependent hydrolase MC49_RS08695 9e2f9331824f31f001cdf7f0d646e083 441 SUPERFAMILY SSF51338 1 56 5.58E-26 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS08695 9e2f9331824f31f001cdf7f0d646e083 441 SUPERFAMILY SSF51338 361 435 5.58E-26 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS08695 9e2f9331824f31f001cdf7f0d646e083 441 Gene3D G3DSA:3.20.20.140 66 347 9.6E-28 T 29-03-2018 MC49_RS01770 4c52dda45296df4c4092decfea7507ae 682 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 307 313 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MC49_RS01770 4c52dda45296df4c4092decfea7507ae 682 Gene3D G3DSA:3.40.50.1000 443 577 2.2E-34 T 29-03-2018 IPR023214 HAD-like domain MC49_RS01770 4c52dda45296df4c4092decfea7507ae 682 Gene3D G3DSA:3.40.1110.10 322 442 7.8E-25 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MC49_RS01770 4c52dda45296df4c4092decfea7507ae 682 Gene3D G3DSA:1.20.1110.10 63 321 1.8E-23 T 29-03-2018 MC49_RS01770 4c52dda45296df4c4092decfea7507ae 682 Pfam PF00702 haloacid dehalogenase-like hydrolase 301 530 1.3E-36 T 29-03-2018 MC49_RS01770 4c52dda45296df4c4092decfea7507ae 682 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 3 677 0.0 T 29-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 MC49_RS01770 4c52dda45296df4c4092decfea7507ae 682 Pfam PF00122 E1-E2 ATPase 114 283 5.4E-34 T 29-03-2018 MC49_RS01770 4c52dda45296df4c4092decfea7507ae 682 SUPERFAMILY SSF56784 372 404 1.46E-38 T 29-03-2018 IPR023214 HAD-like domain MC49_RS01770 4c52dda45296df4c4092decfea7507ae 682 SUPERFAMILY SSF56784 293 317 1.46E-38 T 29-03-2018 IPR023214 HAD-like domain MC49_RS01770 4c52dda45296df4c4092decfea7507ae 682 SUPERFAMILY SSF56784 435 559 1.46E-38 T 29-03-2018 IPR023214 HAD-like domain MC49_RS01770 4c52dda45296df4c4092decfea7507ae 682 SUPERFAMILY SSF81665 619 663 5.36E-15 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MC49_RS01770 4c52dda45296df4c4092decfea7507ae 682 SUPERFAMILY SSF81665 30 103 5.36E-15 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MC49_RS01770 4c52dda45296df4c4092decfea7507ae 682 SUPERFAMILY SSF81665 208 299 5.36E-15 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 MC49_RS01770 4c52dda45296df4c4092decfea7507ae 682 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 373 600 7.3E-49 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MC49_RS01770 4c52dda45296df4c4092decfea7507ae 682 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 71 330 1.5E-35 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MC49_RS01770 4c52dda45296df4c4092decfea7507ae 682 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 8 680 40.744 T 29-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 MC49_RS01770 4c52dda45296df4c4092decfea7507ae 682 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 154 168 3.7E-24 T 29-03-2018 MC49_RS01770 4c52dda45296df4c4092decfea7507ae 682 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 539 551 3.7E-24 T 29-03-2018 MC49_RS01770 4c52dda45296df4c4092decfea7507ae 682 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 463 473 3.7E-24 T 29-03-2018 MC49_RS01770 4c52dda45296df4c4092decfea7507ae 682 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 305 319 3.7E-24 T 29-03-2018 MC49_RS01770 4c52dda45296df4c4092decfea7507ae 682 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 516 535 3.7E-24 T 29-03-2018 MC49_RS01770 4c52dda45296df4c4092decfea7507ae 682 SUPERFAMILY SSF81653 113 207 5.1E-21 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 MC49_RS11440 84546f6c8a1663f3b77364c5ceb41868 877 SUPERFAMILY SSF141729 42 168 1.7E-26 T 29-03-2018 MC49_RS11440 84546f6c8a1663f3b77364c5ceb41868 877 Pfam PF13953 PapC C-terminal domain 798 862 6.8E-23 T 29-03-2018 IPR025949 PapC-like, C-terminal domain MC49_RS11440 84546f6c8a1663f3b77364c5ceb41868 877 Pfam PF00577 Outer membrane usher protein 209 789 1.1E-214 T 29-03-2018 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 MC49_RS11440 84546f6c8a1663f3b77364c5ceb41868 877 Pfam PF13954 PapC N-terminal domain 43 191 3.2E-39 T 29-03-2018 IPR025885 PapC, N-terminal domain GO:0005515 MC49_RS16485 61ccef4812076ef21a48cec83037d9d7 613 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 2 610 7.3E-228 T 29-03-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16485 61ccef4812076ef21a48cec83037d9d7 613 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 157 178 5.3E-55 T 29-03-2018 MC49_RS16485 61ccef4812076ef21a48cec83037d9d7 613 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 225 246 5.3E-55 T 29-03-2018 MC49_RS16485 61ccef4812076ef21a48cec83037d9d7 613 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 247 273 5.3E-55 T 29-03-2018 MC49_RS16485 61ccef4812076ef21a48cec83037d9d7 613 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 418 437 5.3E-55 T 29-03-2018 MC49_RS16485 61ccef4812076ef21a48cec83037d9d7 613 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 315 327 5.3E-55 T 29-03-2018 MC49_RS16485 61ccef4812076ef21a48cec83037d9d7 613 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 82 107 5.3E-55 T 29-03-2018 MC49_RS16485 61ccef4812076ef21a48cec83037d9d7 613 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 110 130 5.3E-55 T 29-03-2018 MC49_RS16485 61ccef4812076ef21a48cec83037d9d7 613 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 64 121 4.2E-22 T 29-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16485 61ccef4812076ef21a48cec83037d9d7 613 Pfam PF00361 Proton-conducting membrane transporter 133 425 4.4E-93 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16485 61ccef4812076ef21a48cec83037d9d7 613 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 58 82 1.7E-9 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 MC49_RS16485 61ccef4812076ef21a48cec83037d9d7 613 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 265 287 1.7E-9 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 MC49_RS16485 61ccef4812076ef21a48cec83037d9d7 613 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 84 104 1.7E-9 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 MC49_RS16485 61ccef4812076ef21a48cec83037d9d7 613 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 417 439 1.7E-9 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 MC49_RS01720 0c023a1c35998e74176caa8e9ecb4818 145 SMART SM00347 30 129 0.0057 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MC49_RS01720 0c023a1c35998e74176caa8e9ecb4818 145 Pfam PF12802 MarR family 37 84 1.3E-6 T 29-03-2018 MC49_RS01720 0c023a1c35998e74176caa8e9ecb4818 145 Gene3D G3DSA:1.10.10.10 7 128 1.4E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS01720 0c023a1c35998e74176caa8e9ecb4818 145 SUPERFAMILY SSF46785 19 137 8.71E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS01720 0c023a1c35998e74176caa8e9ecb4818 145 ProSitePatterns PS01117 MarR-type HTH domain signature. 68 102 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site MC49_RS14180 b12e0435c5d6a1cf674c42f5cecf2ef8 334 Gene3D G3DSA:1.10.3470.10 11 312 2.6E-28 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like MC49_RS14180 b12e0435c5d6a1cf674c42f5cecf2ef8 334 Pfam PF02653 Branched-chain amino acid transport system / permease component 38 307 2.7E-47 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 MC49_RS18825 8f2addf2fa85442316dd3fbc927db39f 331 Gene3D G3DSA:3.40.50.2300 137 331 2.0E-40 T 29-03-2018 MC49_RS18825 8f2addf2fa85442316dd3fbc927db39f 331 Gene3D G3DSA:3.40.50.2300 19 136 3.2E-14 T 29-03-2018 MC49_RS18825 8f2addf2fa85442316dd3fbc927db39f 331 SUPERFAMILY SSF53822 25 330 1.35E-83 T 29-03-2018 IPR028082 Periplasmic binding protein-like I MC49_RS18825 8f2addf2fa85442316dd3fbc927db39f 331 Pfam PF13407 Periplasmic binding protein domain 28 299 2.7E-61 T 29-03-2018 IPR025997 Periplasmic binding protein MC49_RS13910 ba02e2c8e7c1608c5f0c2987a438f67c 206 SUPERFAMILY SSF89392 36 205 1.57E-47 T 29-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX MC49_RS13910 ba02e2c8e7c1608c5f0c2987a438f67c 206 Gene3D G3DSA:2.50.20.10 30 206 2.4E-44 T 29-03-2018 MC49_RS13910 ba02e2c8e7c1608c5f0c2987a438f67c 206 TIGRFAM TIGR00548 lolB: outer membrane lipoprotein LolB 5 204 3.5E-61 T 29-03-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 MC49_RS13910 ba02e2c8e7c1608c5f0c2987a438f67c 206 Pfam PF03550 Outer membrane lipoprotein LolB 50 203 3.6E-45 T 29-03-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 MC49_RS13910 ba02e2c8e7c1608c5f0c2987a438f67c 206 Hamap MF_00233 Outer-membrane lipoprotein LolB [lolB]. 4 205 25.981 T 29-03-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 MC49_RS00690 7052f4d4c0271b77043a9da99d3afdec 112 PRINTS PR00340 P-II protein signature 83 103 2.4E-39 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MC49_RS00690 7052f4d4c0271b77043a9da99d3afdec 112 PRINTS PR00340 P-II protein signature 2 17 2.4E-39 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MC49_RS00690 7052f4d4c0271b77043a9da99d3afdec 112 PRINTS PR00340 P-II protein signature 52 75 2.4E-39 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MC49_RS00690 7052f4d4c0271b77043a9da99d3afdec 112 PRINTS PR00340 P-II protein signature 23 41 2.4E-39 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MC49_RS00690 7052f4d4c0271b77043a9da99d3afdec 112 SMART SM00938 4 105 3.5E-63 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MC49_RS00690 7052f4d4c0271b77043a9da99d3afdec 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 29-03-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 MC49_RS00690 7052f4d4c0271b77043a9da99d3afdec 112 Gene3D G3DSA:3.30.70.120 1 108 1.9E-47 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MC49_RS00690 7052f4d4c0271b77043a9da99d3afdec 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 1.2E-41 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MC49_RS00690 7052f4d4c0271b77043a9da99d3afdec 112 SUPERFAMILY SSF54913 1 112 1.53E-43 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta MC49_RS00690 7052f4d4c0271b77043a9da99d3afdec 112 PIRSF PIRSF039144 1 112 9.0E-50 T 29-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MC49_RS09785 ae0141a726676f114157c33738577137 417 Pfam PF00171 Aldehyde dehydrogenase family 5 282 1.1E-17 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MC49_RS09785 ae0141a726676f114157c33738577137 417 Gene3D G3DSA:3.40.605.10 237 417 2.6E-32 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MC49_RS09785 ae0141a726676f114157c33738577137 417 PIRSF PIRSF000151 1 417 1.3E-171 T 29-03-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 MC49_RS09785 ae0141a726676f114157c33738577137 417 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 1 416 40.718 T 29-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MC49_RS09785 ae0141a726676f114157c33738577137 417 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 323 344 - T 29-03-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MC49_RS09785 ae0141a726676f114157c33738577137 417 Gene3D G3DSA:3.40.605.10 1 236 3.9E-44 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MC49_RS09785 ae0141a726676f114157c33738577137 417 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 9 406 3.7E-183 T 29-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MC49_RS09785 ae0141a726676f114157c33738577137 417 SUPERFAMILY SSF53720 2 415 8.38E-114 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MC49_RS15070 821719414f012d0e3263f854bffacf0b 244 SMART SM00934 16 237 1.9E-100 T 29-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MC49_RS15070 821719414f012d0e3263f854bffacf0b 244 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 14 242 39.562 T 29-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MC49_RS15070 821719414f012d0e3263f854bffacf0b 244 SUPERFAMILY SSF51366 14 240 3.33E-78 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MC49_RS15070 821719414f012d0e3263f854bffacf0b 244 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 15 236 3.5E-50 T 29-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MC49_RS15070 821719414f012d0e3263f854bffacf0b 244 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 17 238 6.7E-57 T 29-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MC49_RS15070 821719414f012d0e3263f854bffacf0b 244 Gene3D G3DSA:3.20.20.70 13 242 2.5E-69 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS15070 821719414f012d0e3263f854bffacf0b 244 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 68 81 - T 29-03-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MC49_RS16890 c5ac2960231f9daa195e0a675a3ed19d 348 Gene3D G3DSA:3.40.50.1980 37 185 1.7E-26 T 29-03-2018 MC49_RS16890 c5ac2960231f9daa195e0a675a3ed19d 348 SUPERFAMILY SSF53807 22 323 2.94E-58 T 29-03-2018 MC49_RS16890 c5ac2960231f9daa195e0a675a3ed19d 348 Pfam PF01497 Periplasmic binding protein 41 295 1.2E-33 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 MC49_RS16890 c5ac2960231f9daa195e0a675a3ed19d 348 Gene3D G3DSA:3.40.50.1980 187 347 8.6E-44 T 29-03-2018 MC49_RS04095 6f7af122b6a05e797984ba215fafd737 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 26.313 T 29-03-2018 IPR023036 Ribosomal protein S14, bacterial/plastid MC49_RS04095 6f7af122b6a05e797984ba215fafd737 101 SUPERFAMILY SSF57716 2 101 4.35E-38 T 29-03-2018 MC49_RS04095 6f7af122b6a05e797984ba215fafd737 101 Pfam PF00253 Ribosomal protein S14p/S29e 47 100 6.8E-27 T 29-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS04095 6f7af122b6a05e797984ba215fafd737 101 ProSitePatterns PS00527 Ribosomal protein S14 signature. 63 85 - T 29-03-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04095 6f7af122b6a05e797984ba215fafd737 101 Gene3D G3DSA:4.10.830.10 1 101 2.4E-33 T 29-03-2018 MC49_RS18630 5cfd4e014f3abfc62eb73d90adca7d86 418 PIRSF PIRSF003101 2 418 3.1E-151 T 29-03-2018 IPR020823 Cell division protein FtsA GO:0007049 MC49_RS18630 5cfd4e014f3abfc62eb73d90adca7d86 418 Pfam PF14450 Cell division protein FtsA 207 381 4.9E-25 T 29-03-2018 MC49_RS18630 5cfd4e014f3abfc62eb73d90adca7d86 418 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 9 385 1.4E-159 T 29-03-2018 IPR020823 Cell division protein FtsA GO:0007049 MC49_RS18630 5cfd4e014f3abfc62eb73d90adca7d86 418 SMART SM00842 10 196 1.3E-95 T 29-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 MC49_RS18630 5cfd4e014f3abfc62eb73d90adca7d86 418 SUPERFAMILY SSF53067 8 221 1.11E-61 T 29-03-2018 MC49_RS18630 5cfd4e014f3abfc62eb73d90adca7d86 418 Gene3D G3DSA:3.90.640.10 246 300 7.5E-19 T 29-03-2018 MC49_RS18630 5cfd4e014f3abfc62eb73d90adca7d86 418 Gene3D G3DSA:3.30.420.40 197 245 8.8E-6 T 29-03-2018 MC49_RS18630 5cfd4e014f3abfc62eb73d90adca7d86 418 Gene3D G3DSA:3.30.420.40 2 186 7.4E-34 T 29-03-2018 MC49_RS18630 5cfd4e014f3abfc62eb73d90adca7d86 418 SUPERFAMILY SSF53067 198 384 2.59E-47 T 29-03-2018 MC49_RS18630 5cfd4e014f3abfc62eb73d90adca7d86 418 Pfam PF02491 SHS2 domain inserted in FTSA 85 162 5.2E-30 T 29-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 MC49_RS18630 5cfd4e014f3abfc62eb73d90adca7d86 418 Hamap MF_02033 Cell division protein FtsA [ftsA]. 6 418 29.395 T 29-03-2018 IPR020823 Cell division protein FtsA GO:0007049 MC49_RS15925 66436ee0270e3bfa0df620b696661641 297 Pfam PF01522 Polysaccharide deacetylase 15 170 5.3E-14 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 MC49_RS15925 66436ee0270e3bfa0df620b696661641 297 Hamap MF_01870 Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD [arnD]. 1 296 65.597 T 29-03-2018 IPR023557 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD, probable GO:0016811 MC49_RS15925 66436ee0270e3bfa0df620b696661641 297 SUPERFAMILY SSF88713 86 275 1.08E-32 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MC49_RS15925 66436ee0270e3bfa0df620b696661641 297 SUPERFAMILY SSF88713 14 41 1.08E-32 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MC49_RS15925 66436ee0270e3bfa0df620b696661641 297 Gene3D G3DSA:3.20.20.370 2 273 6.1E-33 T 29-03-2018 MC49_RS13715 10e889fc5efbc02c187ecfa00a300a8c 324 SMART SM01004 3 321 5.2E-205 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MC49_RS13715 10e889fc5efbc02c187ecfa00a300a8c 324 Gene3D G3DSA:3.20.20.70 1 321 8.4E-137 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS13715 10e889fc5efbc02c187ecfa00a300a8c 324 SUPERFAMILY SSF51569 5 319 1.33E-127 T 29-03-2018 MC49_RS13715 10e889fc5efbc02c187ecfa00a300a8c 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 240 256 6.7E-54 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MC49_RS13715 10e889fc5efbc02c187ecfa00a300a8c 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 265 280 6.7E-54 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MC49_RS13715 10e889fc5efbc02c187ecfa00a300a8c 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 121 135 6.7E-54 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MC49_RS13715 10e889fc5efbc02c187ecfa00a300a8c 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 295 314 6.7E-54 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MC49_RS13715 10e889fc5efbc02c187ecfa00a300a8c 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 151 170 6.7E-54 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MC49_RS13715 10e889fc5efbc02c187ecfa00a300a8c 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 189 208 6.7E-54 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MC49_RS13715 10e889fc5efbc02c187ecfa00a300a8c 324 PIRSF PIRSF001415 1 323 7.9E-142 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MC49_RS13715 10e889fc5efbc02c187ecfa00a300a8c 324 Pfam PF00490 Delta-aminolevulinic acid dehydratase 6 319 7.2E-133 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MC49_RS13715 10e889fc5efbc02c187ecfa00a300a8c 324 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 240 252 - T 29-03-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MC49_RS11470 e43ae56ea8eea236e4200fd51b6c2d23 862 ProSitePatterns PS01151 Fimbrial biogenesis outer membrane usher protein signature. 310 320 - T 29-03-2018 IPR018030 Fimbrial membrane usher, conserved site MC49_RS11470 e43ae56ea8eea236e4200fd51b6c2d23 862 Pfam PF00577 Outer membrane usher protein 195 774 2.5E-205 T 29-03-2018 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 MC49_RS11470 e43ae56ea8eea236e4200fd51b6c2d23 862 Pfam PF13954 PapC N-terminal domain 35 183 2.8E-40 T 29-03-2018 IPR025885 PapC, N-terminal domain GO:0005515 MC49_RS11470 e43ae56ea8eea236e4200fd51b6c2d23 862 SUPERFAMILY SSF141729 59 175 6.67E-29 T 29-03-2018 MC49_RS11470 e43ae56ea8eea236e4200fd51b6c2d23 862 Pfam PF13953 PapC C-terminal domain 783 845 2.2E-20 T 29-03-2018 IPR025949 PapC-like, C-terminal domain MC49_RS03245 86bff378792cc425d312f092bbeef0e1 311 Gene3D G3DSA:3.40.50.1370 147 292 1.7E-47 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MC49_RS03245 86bff378792cc425d312f092bbeef0e1 311 Gene3D G3DSA:3.40.50.1370 1 146 2.9E-53 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MC49_RS03245 86bff378792cc425d312f092bbeef0e1 311 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 7.6E-49 T 29-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 MC49_RS03245 86bff378792cc425d312f092bbeef0e1 311 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 155 303 5.0E-26 T 29-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 MC49_RS03245 86bff378792cc425d312f092bbeef0e1 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 79 88 5.0E-36 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MC49_RS03245 86bff378792cc425d312f092bbeef0e1 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 226 235 5.0E-36 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MC49_RS03245 86bff378792cc425d312f092bbeef0e1 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 39 61 5.0E-36 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MC49_RS03245 86bff378792cc425d312f092bbeef0e1 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 134 151 5.0E-36 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MC49_RS03245 86bff378792cc425d312f092bbeef0e1 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 286 300 5.0E-36 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MC49_RS03245 86bff378792cc425d312f092bbeef0e1 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 264 269 5.0E-36 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MC49_RS03245 86bff378792cc425d312f092bbeef0e1 311 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 49 56 - T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MC49_RS03245 86bff378792cc425d312f092bbeef0e1 311 SUPERFAMILY SSF53671 4 307 6.29E-101 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MC49_RS03245 86bff378792cc425d312f092bbeef0e1 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 260 269 3.2E-25 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MC49_RS03245 86bff378792cc425d312f092bbeef0e1 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 3.2E-25 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MC49_RS03245 86bff378792cc425d312f092bbeef0e1 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 49 68 3.2E-25 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MC49_RS03245 86bff378792cc425d312f092bbeef0e1 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 270 293 3.2E-25 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MC49_RS03245 86bff378792cc425d312f092bbeef0e1 311 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 7 307 38.419 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MC49_RS03245 86bff378792cc425d312f092bbeef0e1 311 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 8 305 2.1E-122 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MC49_RS09165 034bdf897fd75d98889beb63eeabee3e 503 Hamap MF_00030 Deoxyguanosinetriphosphate triphosphohydrolase [dgt]. 1 503 48.444 T 29-03-2018 IPR020779 dNTP triphosphohydrolase, type 1 GO:0000287|GO:0006203|GO:0008832 KEGG: 00230+3.1.5.1 MC49_RS09165 034bdf897fd75d98889beb63eeabee3e 503 SMART SM00471 63 278 1.8E-11 T 29-03-2018 IPR003607 HD/PDEase domain MC49_RS09165 034bdf897fd75d98889beb63eeabee3e 503 Gene3D G3DSA:1.10.3410.10 259 388 2.9E-23 T 29-03-2018 IPR023293 Deoxyguanosinetriphosphate triphosphohydrolase, central domain MC49_RS09165 034bdf897fd75d98889beb63eeabee3e 503 Pfam PF13286 Phosphohydrolase-associated domain 438 498 8.9E-6 T 29-03-2018 IPR026875 Phosphohydrolase-associated domain MC49_RS09165 034bdf897fd75d98889beb63eeabee3e 503 Gene3D G3DSA:1.10.3210.10 3 258 3.5E-55 T 29-03-2018 MC49_RS09165 034bdf897fd75d98889beb63eeabee3e 503 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 31 499 2.1E-119 T 29-03-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 MC49_RS09165 034bdf897fd75d98889beb63eeabee3e 503 Pfam PF01966 HD domain 67 138 3.6E-10 T 29-03-2018 IPR006674 HD domain MC49_RS09165 034bdf897fd75d98889beb63eeabee3e 503 SUPERFAMILY SSF109604 247 430 4.0E-62 T 29-03-2018 MC49_RS09165 034bdf897fd75d98889beb63eeabee3e 503 SUPERFAMILY SSF109604 178 211 4.0E-62 T 29-03-2018 MC49_RS09165 034bdf897fd75d98889beb63eeabee3e 503 SUPERFAMILY SSF109604 482 498 4.0E-62 T 29-03-2018 MC49_RS09165 034bdf897fd75d98889beb63eeabee3e 503 SUPERFAMILY SSF109604 32 135 4.0E-62 T 29-03-2018 MC49_RS19025 c24a63e4ee55e6b88a5849bc10f04327 503 SUPERFAMILY SSF53067 254 494 2.39E-46 T 29-03-2018 MC49_RS19025 c24a63e4ee55e6b88a5849bc10f04327 503 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 263 443 1.9E-22 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 MC49_RS19025 c24a63e4ee55e6b88a5849bc10f04327 503 PIRSF PIRSF000538 1 500 4.1E-109 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MC49_RS19025 c24a63e4ee55e6b88a5849bc10f04327 503 SUPERFAMILY SSF53067 3 254 1.19E-60 T 29-03-2018 MC49_RS19025 c24a63e4ee55e6b88a5849bc10f04327 503 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 3 252 5.0E-66 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 MC49_RS19025 c24a63e4ee55e6b88a5849bc10f04327 503 Gene3D G3DSA:3.30.420.40 250 500 1.2E-52 T 29-03-2018 MC49_RS19025 c24a63e4ee55e6b88a5849bc10f04327 503 TIGRFAM TIGR01312 XylB: xylulokinase 6 494 1.3E-160 T 29-03-2018 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 MC49_RS19025 c24a63e4ee55e6b88a5849bc10f04327 503 Gene3D G3DSA:3.30.420.40 1 249 2.5E-69 T 29-03-2018 MC49_RS04150 acea9a27c8545fa722659e9506c71b23 100 Pfam PF00276 Ribosomal protein L23 9 95 3.7E-32 T 29-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 MC49_RS04150 acea9a27c8545fa722659e9506c71b23 100 Gene3D G3DSA:3.30.70.330 6 100 2.5E-31 T 29-03-2018 MC49_RS04150 acea9a27c8545fa722659e9506c71b23 100 SUPERFAMILY SSF54189 3 92 1.91E-31 T 29-03-2018 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS04150 acea9a27c8545fa722659e9506c71b23 100 ProSitePatterns PS00050 Ribosomal protein L23 signature. 81 96 - T 29-03-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04150 acea9a27c8545fa722659e9506c71b23 100 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 8 98 22.906 T 29-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 MC49_RS14880 f4410e617f9fcb33289ac930530ca7cd 222 Gene3D G3DSA:3.40.630.30 2 219 5.8E-21 T 29-03-2018 MC49_RS14880 f4410e617f9fcb33289ac930530ca7cd 222 Pfam PF00583 Acetyltransferase (GNAT) family 110 192 1.4E-10 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MC49_RS14880 f4410e617f9fcb33289ac930530ca7cd 222 SUPERFAMILY SSF55729 29 211 4.91E-20 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS17435 cc0bbb48d941549e6f822d742026c09c 239 Gene3D G3DSA:3.40.630.30 7 133 3.9E-4 T 29-03-2018 MC49_RS03255 0a91fd73a74218434deaaee88110ba8f 128 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 103 121 - T 29-03-2018 IPR019897 RidA, conserved site MC49_RS03255 0a91fd73a74218434deaaee88110ba8f 128 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 3 126 7.1E-53 T 29-03-2018 IPR006056 RidA family MC49_RS03255 0a91fd73a74218434deaaee88110ba8f 128 Pfam PF01042 Endoribonuclease L-PSP 7 126 2.7E-45 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family MC49_RS03255 0a91fd73a74218434deaaee88110ba8f 128 SUPERFAMILY SSF55298 3 127 7.23E-45 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like MC49_RS03255 0a91fd73a74218434deaaee88110ba8f 128 Gene3D G3DSA:3.30.1330.40 1 128 9.3E-46 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like MC49_RS15055 31c45a4669980be87dde272b9d55aedd 645 SMART SM00955 191 519 1.1E-118 T 29-03-2018 MC49_RS15055 31c45a4669980be87dde272b9d55aedd 645 SUPERFAMILY SSF50249 563 643 7.5E-18 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS15055 31c45a4669980be87dde272b9d55aedd 645 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 6 643 2.5E-213 T 29-03-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 MC49_RS15055 31c45a4669980be87dde272b9d55aedd 645 Pfam PF08206 Ribonuclease B OB domain 24 79 2.0E-17 T 29-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain MC49_RS15055 31c45a4669980be87dde272b9d55aedd 645 Pfam PF00575 S1 RNA binding domain 566 640 5.6E-7 T 29-03-2018 IPR003029 S1 domain GO:0003676 MC49_RS15055 31c45a4669980be87dde272b9d55aedd 645 Pfam PF00773 RNB domain 191 518 3.4E-84 T 29-03-2018 MC49_RS15055 31c45a4669980be87dde272b9d55aedd 645 SUPERFAMILY SSF50249 83 171 7.54E-29 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS15055 31c45a4669980be87dde272b9d55aedd 645 TIGRFAM TIGR02062 RNase_B: exoribonuclease II 1 644 3.4E-302 T 29-03-2018 IPR011804 Ribonuclease II GO:0003723|GO:0006401|GO:0008859 MC49_RS15055 31c45a4669980be87dde272b9d55aedd 645 Hamap MF_01036 Exoribonuclease 2 [rnb]. 1 645 43.683 T 29-03-2018 IPR011804 Ribonuclease II GO:0003723|GO:0006401|GO:0008859 MC49_RS15055 31c45a4669980be87dde272b9d55aedd 645 SMART SM00357 23 79 7.9E-12 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 MC49_RS15055 31c45a4669980be87dde272b9d55aedd 645 ProSitePatterns PS01175 Ribonuclease II family signature. 486 510 - T 29-03-2018 IPR022966 Ribonuclease II/R, conserved site MC49_RS15055 31c45a4669980be87dde272b9d55aedd 645 SMART SM00316 17 82 23.0 T 29-03-2018 IPR022967 RNA-binding domain, S1 MC49_RS15055 31c45a4669980be87dde272b9d55aedd 645 SMART SM00316 561 645 0.016 T 29-03-2018 IPR022967 RNA-binding domain, S1 MC49_RS15055 31c45a4669980be87dde272b9d55aedd 645 SUPERFAMILY SSF50249 190 558 1.03E-112 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS15055 31c45a4669980be87dde272b9d55aedd 645 Gene3D G3DSA:2.40.50.140 560 645 1.3E-4 T 29-03-2018 MC49_RS15055 31c45a4669980be87dde272b9d55aedd 645 SUPERFAMILY SSF50249 8 75 3.5E-15 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS15055 31c45a4669980be87dde272b9d55aedd 645 Gene3D G3DSA:2.40.50.140 21 72 0.011 T 29-03-2018 MC49_RS01070 890a83087660133b17300371c3b3fc1d 90 ProDom PD012561 TRBD PLASMID CONJUGAL TRANSFER PRECURSOR SIGNAL MATING FORMATION PROBABLE PAIR 15 86 6.0E-5 T 29-03-2018 MC49_RS01070 890a83087660133b17300371c3b3fc1d 90 PIRSF PIRSF017854 5 90 2.8E-35 T 29-03-2018 IPR016704 Conjugal transfer, TrbD MC49_RS01070 890a83087660133b17300371c3b3fc1d 90 Pfam PF05101 Type IV secretory pathway, VirB3-like protein 12 82 2.3E-11 T 29-03-2018 IPR007792 Type IV secretion system, VirB3 / TrbD / AvhB MC49_RS10680 3a9ddb529115c678f3c4a83cc42c8874 279 Gene3D G3DSA:3.40.250.10 1 154 2.8E-30 T 29-03-2018 IPR001763 Rhodanese-like domain MC49_RS10680 3a9ddb529115c678f3c4a83cc42c8874 279 SUPERFAMILY SSF52821 159 278 5.24E-36 T 29-03-2018 IPR001763 Rhodanese-like domain MC49_RS10680 3a9ddb529115c678f3c4a83cc42c8874 279 Gene3D G3DSA:3.40.250.10 156 279 2.2E-29 T 29-03-2018 IPR001763 Rhodanese-like domain MC49_RS10680 3a9ddb529115c678f3c4a83cc42c8874 279 ProSitePatterns PS00683 Rhodanese C-terminal signature. 259 269 - T 29-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 MC49_RS10680 3a9ddb529115c678f3c4a83cc42c8874 279 Pfam PF00581 Rhodanese-like domain 8 126 1.0E-15 T 29-03-2018 IPR001763 Rhodanese-like domain MC49_RS10680 3a9ddb529115c678f3c4a83cc42c8874 279 Pfam PF00581 Rhodanese-like domain 160 269 1.4E-13 T 29-03-2018 IPR001763 Rhodanese-like domain MC49_RS10680 3a9ddb529115c678f3c4a83cc42c8874 279 SUPERFAMILY SSF52821 2 141 1.15E-38 T 29-03-2018 IPR001763 Rhodanese-like domain MC49_RS10680 3a9ddb529115c678f3c4a83cc42c8874 279 SMART SM00450 7 131 7.1E-19 T 29-03-2018 IPR001763 Rhodanese-like domain MC49_RS10680 3a9ddb529115c678f3c4a83cc42c8874 279 SMART SM00450 155 275 2.8E-24 T 29-03-2018 IPR001763 Rhodanese-like domain MC49_RS04795 001b872cdd95441772476a6e04bcbef2 252 Gene3D G3DSA:3.40.50.150 57 252 2.9E-37 T 29-03-2018 MC49_RS04795 001b872cdd95441772476a6e04bcbef2 252 Pfam PF04445 Putative SAM-dependent methyltransferase 19 246 9.7E-109 T 29-03-2018 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 MC49_RS04795 001b872cdd95441772476a6e04bcbef2 252 Hamap MF_01523 Ribosomal RNA small subunit methyltransferase J [rsmJ]. 3 248 38.696 T 29-03-2018 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 MC49_RS04795 001b872cdd95441772476a6e04bcbef2 252 Gene3D G3DSA:3.40.1630.10 3 55 1.1E-21 T 29-03-2018 MC49_RS04795 001b872cdd95441772476a6e04bcbef2 252 SUPERFAMILY SSF53335 17 247 1.24E-75 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS09370 8cc7eeb5789f777398a7abd9f17737c7 251 SMART SM01134 72 232 5.7E-51 T 29-03-2018 MC49_RS09370 8cc7eeb5789f777398a7abd9f17737c7 251 SUPERFAMILY SSF46785 5 60 1.0E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS09370 8cc7eeb5789f777398a7abd9f17737c7 251 Pfam PF00455 DeoR C terminal sensor domain 74 230 2.6E-39 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain MC49_RS09370 8cc7eeb5789f777398a7abd9f17737c7 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 2.4E-8 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MC49_RS09370 8cc7eeb5789f777398a7abd9f17737c7 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 2.4E-8 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MC49_RS09370 8cc7eeb5789f777398a7abd9f17737c7 251 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 1.6E-18 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MC49_RS09370 8cc7eeb5789f777398a7abd9f17737c7 251 SMART SM00420 6 58 1.0E-18 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MC49_RS09370 8cc7eeb5789f777398a7abd9f17737c7 251 SUPERFAMILY SSF100950 74 232 4.81E-23 T 29-03-2018 MC49_RS09370 8cc7eeb5789f777398a7abd9f17737c7 251 Gene3D G3DSA:1.10.10.10 1 59 5.5E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS09370 8cc7eeb5789f777398a7abd9f17737c7 251 Gene3D G3DSA:3.40.50.1360 72 238 1.0E-29 T 29-03-2018 MC49_RS09370 8cc7eeb5789f777398a7abd9f17737c7 251 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 MC49_RS10495 1ee3a89f72a38d30bb1158ec52b5e08e 309 Pfam PF05661 Protein of unknown function (DUF808) 5 295 8.6E-118 T 29-03-2018 IPR008526 Inner membrane protein YedI MC49_RS10495 1ee3a89f72a38d30bb1158ec52b5e08e 309 PIRSF PIRSF016660 1 307 3.9E-126 T 29-03-2018 IPR008526 Inner membrane protein YedI MC49_RS04015 e48f77ad79c64e84e8bfd4cccc6f8532 135 Gene3D G3DSA:1.20.5.220 115 132 7.5E-4 T 29-03-2018 MC49_RS04015 e48f77ad79c64e84e8bfd4cccc6f8532 135 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 93 102 3.0E-14 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 MC49_RS04015 e48f77ad79c64e84e8bfd4cccc6f8532 135 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 84 92 3.0E-14 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 MC49_RS04015 e48f77ad79c64e84e8bfd4cccc6f8532 135 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 6 20 3.0E-14 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 MC49_RS04015 e48f77ad79c64e84e8bfd4cccc6f8532 135 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 13 26 - T 29-03-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site MC49_RS04015 e48f77ad79c64e84e8bfd4cccc6f8532 135 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 3 134 30.279 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 MC49_RS04015 e48f77ad79c64e84e8bfd4cccc6f8532 135 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 3 133 5.4E-55 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 MC49_RS04015 e48f77ad79c64e84e8bfd4cccc6f8532 135 SUPERFAMILY SSF81330 12 127 1.18E-35 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 MC49_RS04015 e48f77ad79c64e84e8bfd4cccc6f8532 135 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 3 131 3.7E-45 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 MC49_RS17070 be0a9c91742187edd33030f59657c6bd 212 Gene3D G3DSA:3.40.50.300 1 212 3.0E-51 T 29-03-2018 MC49_RS17070 be0a9c91742187edd33030f59657c6bd 212 Hamap MF_00165 Thymidylate kinase [tmk]. 4 206 29.003 T 29-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 MC49_RS17070 be0a9c91742187edd33030f59657c6bd 212 ProSitePatterns PS01331 Thymidylate kinase signature. 95 107 - T 29-03-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 MC49_RS17070 be0a9c91742187edd33030f59657c6bd 212 SUPERFAMILY SSF52540 1 206 7.27E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS17070 be0a9c91742187edd33030f59657c6bd 212 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 198 1.3E-65 T 29-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 MC49_RS17070 be0a9c91742187edd33030f59657c6bd 212 Pfam PF02223 Thymidylate kinase 8 198 3.1E-60 T 29-03-2018 MC49_RS09020 7c5f356387a181823665eec0b12b67f6 295 Hamap MF_00158 Pantothenate synthetase [panC]. 2 280 31.838 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 MC49_RS09020 7c5f356387a181823665eec0b12b67f6 295 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 280 2.8E-82 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 MC49_RS09020 7c5f356387a181823665eec0b12b67f6 295 Gene3D G3DSA:3.40.50.620 1 176 5.5E-60 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS09020 7c5f356387a181823665eec0b12b67f6 295 SUPERFAMILY SSF52374 1 280 3.49E-80 T 29-03-2018 MC49_RS09020 7c5f356387a181823665eec0b12b67f6 295 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 23 84 4.3E-10 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MC49_RS09020 7c5f356387a181823665eec0b12b67f6 295 Pfam PF02569 Pantoate-beta-alanine ligase 3 277 7.0E-83 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 MC49_RS09020 7c5f356387a181823665eec0b12b67f6 295 Gene3D G3DSA:3.30.1300.10 177 294 8.4E-23 T 29-03-2018 MC49_RS09770 9f613094c153f932d18b801e1a9d385e 415 Gene3D G3DSA:1.20.1440.110 49 163 1.6E-21 T 29-03-2018 MC49_RS09770 9f613094c153f932d18b801e1a9d385e 415 Gene3D G3DSA:3.40.50.1820 164 414 9.2E-23 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS09770 9f613094c153f932d18b801e1a9d385e 415 SUPERFAMILY SSF53474 46 414 5.09E-48 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS09770 9f613094c153f932d18b801e1a9d385e 415 Pfam PF06500 Alpha/beta hydrolase of unknown function (DUF1100) 1 411 9.2E-166 T 29-03-2018 IPR010520 UPF0255 family MC49_RS09770 9f613094c153f932d18b801e1a9d385e 415 Hamap MF_01063 Esterase FrsA [frsA]. 1 415 54.835 T 29-03-2018 IPR010520 UPF0255 family MC49_RS02845 63bed35ba84267b638decc94c9149326 394 Gene3D G3DSA:1.20.1250.20 201 387 0.3 T 29-03-2018 MC49_RS02845 63bed35ba84267b638decc94c9149326 394 SUPERFAMILY SSF103473 4 382 6.41E-44 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS02845 63bed35ba84267b638decc94c9149326 394 Gene3D G3DSA:1.20.1250.20 2 196 1.4E-30 T 29-03-2018 MC49_RS02845 63bed35ba84267b638decc94c9149326 394 ProSitePatterns PS00216 Sugar transport proteins signature 1. 58 75 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MC49_RS02845 63bed35ba84267b638decc94c9149326 394 Pfam PF07690 Major Facilitator Superfamily 10 342 6.8E-38 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS07295 4fd3c69e06697e799742d24b8418631a 529 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 15 157 1.6E-18 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MC49_RS07295 4fd3c69e06697e799742d24b8418631a 529 Pfam PF16658 Class II release factor RF3, C-terminal domain 387 514 6.3E-46 T 29-03-2018 IPR032090 Peptide chain release factor 3, C-terminal MC49_RS07295 4fd3c69e06697e799742d24b8418631a 529 Pfam PF00009 Elongation factor Tu GTP binding domain 13 277 2.2E-46 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS07295 4fd3c69e06697e799742d24b8418631a 529 SUPERFAMILY SSF50447 262 393 1.67E-26 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain MC49_RS07295 4fd3c69e06697e799742d24b8418631a 529 PRINTS PR00315 GTP-binding elongation factor signature 101 112 6.6E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS07295 4fd3c69e06697e799742d24b8418631a 529 PRINTS PR00315 GTP-binding elongation factor signature 15 28 6.6E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS07295 4fd3c69e06697e799742d24b8418631a 529 PRINTS PR00315 GTP-binding elongation factor signature 137 146 6.6E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS07295 4fd3c69e06697e799742d24b8418631a 529 PRINTS PR00315 GTP-binding elongation factor signature 85 95 6.6E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS07295 4fd3c69e06697e799742d24b8418631a 529 PRINTS PR00315 GTP-binding elongation factor signature 65 73 6.6E-11 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS07295 4fd3c69e06697e799742d24b8418631a 529 Gene3D G3DSA:3.40.50.300 8 280 9.6E-37 T 29-03-2018 MC49_RS07295 4fd3c69e06697e799742d24b8418631a 529 Gene3D G3DSA:3.30.70.870 388 465 2.7E-10 T 29-03-2018 MC49_RS07295 4fd3c69e06697e799742d24b8418631a 529 Pfam PF03144 Elongation factor Tu domain 2 314 380 7.5E-9 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MC49_RS07295 4fd3c69e06697e799742d24b8418631a 529 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 5 529 0.0 T 29-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 MC49_RS07295 4fd3c69e06697e799742d24b8418631a 529 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 58 73 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site MC49_RS07295 4fd3c69e06697e799742d24b8418631a 529 Gene3D G3DSA:2.40.30.10 281 385 1.1E-20 T 29-03-2018 MC49_RS07295 4fd3c69e06697e799742d24b8418631a 529 SUPERFAMILY SSF52540 10 277 1.9E-84 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS07295 4fd3c69e06697e799742d24b8418631a 529 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 4 527 51.955 T 29-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 MC49_RS07295 4fd3c69e06697e799742d24b8418631a 529 SUPERFAMILY SSF54980 393 468 6.12E-17 T 29-03-2018 IPR035647 EF-G domain III/V-like MC49_RS14335 75092f7e57f033f88405f61af7114997 333 SUPERFAMILY SSF52283 2 137 2.46E-42 T 29-03-2018 MC49_RS14335 75092f7e57f033f88405f61af7114997 333 Gene3D G3DSA:3.40.50.720 118 302 6.9E-52 T 29-03-2018 MC49_RS14335 75092f7e57f033f88405f61af7114997 333 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 225 241 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site MC49_RS14335 75092f7e57f033f88405f61af7114997 333 Gene3D G3DSA:3.40.50.720 1 117 4.8E-29 T 29-03-2018 MC49_RS14335 75092f7e57f033f88405f61af7114997 333 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 112 299 5.3E-55 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MC49_RS14335 75092f7e57f033f88405f61af7114997 333 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 12 330 2.0E-33 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 MC49_RS14335 75092f7e57f033f88405f61af7114997 333 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 196 218 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site MC49_RS14335 75092f7e57f033f88405f61af7114997 333 SUPERFAMILY SSF51735 104 300 3.95E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS05590 222dbfedfbec9cd56b675b59b84d81a0 425 Gene3D G3DSA:3.40.50.2000 51 198 9.8E-5 T 29-03-2018 MC49_RS05590 222dbfedfbec9cd56b675b59b84d81a0 425 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 34 211 1.5E-64 T 29-03-2018 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 MC49_RS05590 222dbfedfbec9cd56b675b59b84d81a0 425 Pfam PF00534 Glycosyl transferases group 1 291 399 8.3E-11 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 MC49_RS05590 222dbfedfbec9cd56b675b59b84d81a0 425 SUPERFAMILY SSF53756 58 402 3.01E-17 T 29-03-2018 MC49_RS05590 222dbfedfbec9cd56b675b59b84d81a0 425 Gene3D G3DSA:3.40.50.2000 210 405 1.2E-15 T 29-03-2018 MC49_RS16190 702252ba17c16487d26c8e4db67bdaa7 185 Gene3D G3DSA:2.160.20.10 38 183 3.7E-21 T 29-03-2018 IPR012334 Pectin lyase fold MC49_RS16190 702252ba17c16487d26c8e4db67bdaa7 185 SUPERFAMILY SSF51126 48 138 7.74E-22 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor MC49_RS16190 702252ba17c16487d26c8e4db67bdaa7 185 SMART SM00912 52 152 5.6E-6 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal MC49_RS16190 702252ba17c16487d26c8e4db67bdaa7 185 Pfam PF05860 haemagglutination activity domain 51 138 1.2E-21 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal MC49_RS16190 702252ba17c16487d26c8e4db67bdaa7 185 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 70 138 4.7E-15 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal MC49_RS11585 5cc27fb0c31ee326e6f293fee5689845 385 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 40 385 4.7E-81 T 29-03-2018 IPR010327 FldB/FldC dehydratase alpha/beta subunit MC49_RS10755 e25298c2ca7756fe5d3d4e01f8698128 219 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 34 217 33.855 T 29-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MC49_RS10755 e25298c2ca7756fe5d3d4e01f8698128 219 SUPERFAMILY SSF55620 6 217 1.26E-74 T 29-03-2018 MC49_RS10755 e25298c2ca7756fe5d3d4e01f8698128 219 Pfam PF01227 GTP cyclohydrolase I 38 215 8.9E-64 T 29-03-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MC49_RS10755 e25298c2ca7756fe5d3d4e01f8698128 219 Gene3D G3DSA:3.30.1130.10 88 218 4.3E-46 T 29-03-2018 MC49_RS10755 e25298c2ca7756fe5d3d4e01f8698128 219 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 96 112 - T 29-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MC49_RS10755 e25298c2ca7756fe5d3d4e01f8698128 219 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 144 154 - T 29-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MC49_RS10755 e25298c2ca7756fe5d3d4e01f8698128 219 Gene3D G3DSA:1.10.286.10 7 83 1.3E-22 T 29-03-2018 MC49_RS10755 e25298c2ca7756fe5d3d4e01f8698128 219 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 38 217 2.0E-84 T 29-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MC49_RS15220 aedb68ce6bc7126f63f30b1c6e7beb73 179 Hamap MF_00189 Probable intracellular septation protein A [yciB]. 1 176 18.923 T 29-03-2018 IPR006008 Intracellular septation protein A GO:0016021 MC49_RS15220 aedb68ce6bc7126f63f30b1c6e7beb73 179 Pfam PF04279 Intracellular septation protein A 1 175 7.5E-68 T 29-03-2018 IPR006008 Intracellular septation protein A GO:0016021 MC49_RS15220 aedb68ce6bc7126f63f30b1c6e7beb73 179 TIGRFAM TIGR00997 ispZ: intracellular septation protein A 1 177 4.7E-67 T 29-03-2018 IPR006008 Intracellular septation protein A GO:0016021 MC49_RS16925 e10bf601ed8995ad61ce879b65a47327 417 SMART SM01329 29 413 4.2E-178 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MC49_RS16925 e10bf601ed8995ad61ce879b65a47327 417 SUPERFAMILY SSF53659 5 417 2.11E-148 T 29-03-2018 MC49_RS16925 e10bf601ed8995ad61ce879b65a47327 417 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 304 323 - T 29-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 MC49_RS16925 e10bf601ed8995ad61ce879b65a47327 417 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 1 417 1.2E-232 T 29-03-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 MC49_RS16925 e10bf601ed8995ad61ce879b65a47327 417 Gene3D G3DSA:3.40.718.10 9 417 4.9E-134 T 29-03-2018 MC49_RS16925 e10bf601ed8995ad61ce879b65a47327 417 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 30 413 1.1E-117 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MC49_RS09495 33cc6a80d01b7447c4f46efcfe8447c5 232 Pfam PF00005 ABC transporter 25 169 2.5E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS09495 33cc6a80d01b7447c4f46efcfe8447c5 232 SMART SM00382 34 219 9.7E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS09495 33cc6a80d01b7447c4f46efcfe8447c5 232 Gene3D G3DSA:3.40.50.300 1 232 1.1E-64 T 29-03-2018 MC49_RS09495 33cc6a80d01b7447c4f46efcfe8447c5 232 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS09495 33cc6a80d01b7447c4f46efcfe8447c5 232 SUPERFAMILY SSF52540 6 229 2.4E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS06795 0e5ff97da10c2d24a04e418c77ccb721 67 Gene3D G3DSA:1.10.10.10 5 65 3.8E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS14100 e2081d7b7c758e75d5ec9ce18967dcc8 480 Gene3D G3DSA:3.20.20.60 171 327 4.2E-56 T 29-03-2018 MC49_RS14100 e2081d7b7c758e75d5ec9ce18967dcc8 480 ProSitePatterns PS00110 Pyruvate kinase active site signature. 218 230 - T 29-03-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MC49_RS14100 e2081d7b7c758e75d5ec9ce18967dcc8 480 Gene3D G3DSA:2.40.33.10 86 170 9.5E-22 T 29-03-2018 MC49_RS14100 e2081d7b7c758e75d5ec9ce18967dcc8 480 SUPERFAMILY SSF50800 74 169 8.37E-24 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain MC49_RS14100 e2081d7b7c758e75d5ec9ce18967dcc8 480 Pfam PF00224 Pyruvate kinase, barrel domain 6 344 1.1E-129 T 29-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MC49_RS14100 e2081d7b7c758e75d5ec9ce18967dcc8 480 PRINTS PR01050 Pyruvate kinase family signature 300 318 1.5E-51 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MC49_RS14100 e2081d7b7c758e75d5ec9ce18967dcc8 480 PRINTS PR01050 Pyruvate kinase family signature 250 274 1.5E-51 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MC49_RS14100 e2081d7b7c758e75d5ec9ce18967dcc8 480 PRINTS PR01050 Pyruvate kinase family signature 63 79 1.5E-51 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MC49_RS14100 e2081d7b7c758e75d5ec9ce18967dcc8 480 PRINTS PR01050 Pyruvate kinase family signature 190 204 1.5E-51 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MC49_RS14100 e2081d7b7c758e75d5ec9ce18967dcc8 480 PRINTS PR01050 Pyruvate kinase family signature 275 299 1.5E-51 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MC49_RS14100 e2081d7b7c758e75d5ec9ce18967dcc8 480 PRINTS PR01050 Pyruvate kinase family signature 319 335 1.5E-51 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MC49_RS14100 e2081d7b7c758e75d5ec9ce18967dcc8 480 PRINTS PR01050 Pyruvate kinase family signature 223 249 1.5E-51 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MC49_RS14100 e2081d7b7c758e75d5ec9ce18967dcc8 480 Gene3D G3DSA:3.20.20.60 1 85 3.1E-16 T 29-03-2018 MC49_RS14100 e2081d7b7c758e75d5ec9ce18967dcc8 480 SUPERFAMILY SSF52935 329 479 1.7E-40 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MC49_RS14100 e2081d7b7c758e75d5ec9ce18967dcc8 480 SUPERFAMILY SSF51621 171 345 1.81E-88 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MC49_RS14100 e2081d7b7c758e75d5ec9ce18967dcc8 480 SUPERFAMILY SSF51621 4 79 1.81E-88 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MC49_RS14100 e2081d7b7c758e75d5ec9ce18967dcc8 480 Gene3D G3DSA:3.40.1380.20 328 480 9.2E-46 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MC49_RS14100 e2081d7b7c758e75d5ec9ce18967dcc8 480 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 6 479 8.2E-169 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MC49_RS14100 e2081d7b7c758e75d5ec9ce18967dcc8 480 Pfam PF02887 Pyruvate kinase, alpha/beta domain 363 477 1.7E-31 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MC49_RS19015 e67e86d3298fb1331aea36d5df04c3b6 181 SUPERFAMILY SSF51182 53 98 9.89E-6 T 29-03-2018 IPR011051 RmlC-like cupin domain MC49_RS19015 e67e86d3298fb1331aea36d5df04c3b6 181 SUPERFAMILY SSF51182 127 173 9.89E-6 T 29-03-2018 IPR011051 RmlC-like cupin domain MC49_RS19015 e67e86d3298fb1331aea36d5df04c3b6 181 Gene3D G3DSA:2.60.120.10 13 178 5.3E-10 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MC49_RS19015 e67e86d3298fb1331aea36d5df04c3b6 181 Pfam PF07385 D-lyxose isomerase 30 173 6.0E-6 T 29-03-2018 IPR010864 D-lyxose isomerase KEGG: 00040+5.3.1.15 MC49_RS15000 d16af9bb2633aae81fc8a2aee7331f6a 335 SUPERFAMILY SSF51556 4 325 2.52E-74 T 29-03-2018 IPR032466 Metal-dependent hydrolase MC49_RS15000 d16af9bb2633aae81fc8a2aee7331f6a 335 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 6 327 2.2E-104 T 29-03-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 MC49_RS15000 d16af9bb2633aae81fc8a2aee7331f6a 335 Pfam PF00962 Adenosine/AMP deaminase 6 327 7.2E-87 T 29-03-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 MC49_RS15000 d16af9bb2633aae81fc8a2aee7331f6a 335 Gene3D G3DSA:3.20.20.140 2 334 8.2E-70 T 29-03-2018 MC49_RS15000 d16af9bb2633aae81fc8a2aee7331f6a 335 Hamap MF_00540 Adenosine deaminase [add]. 1 331 51.552 T 29-03-2018 IPR028893 Adenosine deaminase GO:0004000|GO:0009168 KEGG: 00230+3.5.4.4|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217 MC49_RS12700 f0d60fd29f26277edb1cc603c509a4bb 383 SUPERFAMILY SSF64518 1 383 5.49E-101 T 29-03-2018 MC49_RS12700 f0d60fd29f26277edb1cc603c509a4bb 383 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 142 1.1E-40 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 MC49_RS12700 f0d60fd29f26277edb1cc603c509a4bb 383 Pfam PF00700 Bacterial flagellin C-terminal helical region 298 382 4.4E-31 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 MC49_RS12700 f0d60fd29f26277edb1cc603c509a4bb 383 PRINTS PR00207 Flagellin signature 37 54 4.2E-28 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 MC49_RS12700 f0d60fd29f26277edb1cc603c509a4bb 383 PRINTS PR00207 Flagellin signature 111 134 4.2E-28 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 MC49_RS12700 f0d60fd29f26277edb1cc603c509a4bb 383 PRINTS PR00207 Flagellin signature 76 95 4.2E-28 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 MC49_RS12700 f0d60fd29f26277edb1cc603c509a4bb 383 Gene3D G3DSA:1.20.1330.10 40 355 1.7E-70 T 29-03-2018 MC49_RS16120 3cb64237f93f9ec0aef1f63a2174a3ad 294 Gene3D G3DSA:3.40.50.1360 115 284 1.9E-27 T 29-03-2018 MC49_RS16120 3cb64237f93f9ec0aef1f63a2174a3ad 294 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 81 99 9.3E-8 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MC49_RS16120 3cb64237f93f9ec0aef1f63a2174a3ad 294 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 67 81 9.3E-8 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MC49_RS16120 3cb64237f93f9ec0aef1f63a2174a3ad 294 SUPERFAMILY SSF46785 47 102 4.01E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS16120 3cb64237f93f9ec0aef1f63a2174a3ad 294 Pfam PF00455 DeoR C terminal sensor domain 116 271 3.4E-38 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain MC49_RS16120 3cb64237f93f9ec0aef1f63a2174a3ad 294 Gene3D G3DSA:1.10.10.10 42 114 2.2E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS16120 3cb64237f93f9ec0aef1f63a2174a3ad 294 SMART SM00420 49 101 9.6E-16 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MC49_RS16120 3cb64237f93f9ec0aef1f63a2174a3ad 294 ProSitePatterns PS00894 DeoR-type HTH domain signature. 49 83 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 MC49_RS16120 3cb64237f93f9ec0aef1f63a2174a3ad 294 SMART SM01134 114 275 7.0E-52 T 29-03-2018 MC49_RS16120 3cb64237f93f9ec0aef1f63a2174a3ad 294 Pfam PF08220 DeoR-like helix-turn-helix domain 49 101 1.7E-15 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MC49_RS16120 3cb64237f93f9ec0aef1f63a2174a3ad 294 SUPERFAMILY SSF100950 116 272 1.09E-19 T 29-03-2018 MC49_RS17285 e81600d9b3242ec0f0d3fdc93cd24508 93 Gene3D G3DSA:2.40.240.10 1 93 8.9E-31 T 29-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MC49_RS17285 e81600d9b3242ec0f0d3fdc93cd24508 93 SUPERFAMILY SSF50715 1 92 7.5E-31 T 29-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MC49_RS17285 e81600d9b3242ec0f0d3fdc93cd24508 93 Hamap MF_01336 50S ribosomal protein L25 [rplY]. 2 93 28.731 T 29-03-2018 IPR020055 Ribosomal protein L25, short-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 MC49_RS17285 e81600d9b3242ec0f0d3fdc93cd24508 93 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 6 92 7.0E-38 T 29-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 MC49_RS17285 e81600d9b3242ec0f0d3fdc93cd24508 93 Pfam PF01386 Ribosomal L25p family 4 90 3.6E-25 T 29-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 MC49_RS08405 638910b9144f46e05bfe97b8d880fe25 260 SUPERFAMILY SSF53800 2 257 1.09E-80 T 29-03-2018 MC49_RS08405 638910b9144f46e05bfe97b8d880fe25 260 Pfam PF06180 Cobalt chelatase (CbiK) 3 256 6.8E-101 T 29-03-2018 IPR010388 Anaerobic cobalt chelatase GO:0016852|GO:0019251 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 MC49_RS08405 638910b9144f46e05bfe97b8d880fe25 260 Gene3D G3DSA:3.40.50.1400 1 124 2.1E-14 T 29-03-2018 MC49_RS08405 638910b9144f46e05bfe97b8d880fe25 260 PIRSF PIRSF033579 1 260 1.7E-105 T 29-03-2018 IPR010388 Anaerobic cobalt chelatase GO:0016852|GO:0019251 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 MC49_RS08405 638910b9144f46e05bfe97b8d880fe25 260 Gene3D G3DSA:3.40.50.1400 125 236 4.5E-21 T 29-03-2018 MC49_RS01840 e8cfff5f3379eaf6f10e42cc2e9693b0 81 Gene3D G3DSA:1.10.150.20 22 79 7.4E-8 T 29-03-2018 MC49_RS01840 e8cfff5f3379eaf6f10e42cc2e9693b0 81 Gene3D G3DSA:1.10.150.20 2 21 0.39 T 29-03-2018 MC49_RS11340 50ebfc43a4e885d50c68509fea500b35 137 SUPERFAMILY SSF51735 3 135 8.75E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS11340 50ebfc43a4e885d50c68509fea500b35 137 Pfam PF13380 CoA binding domain 14 130 1.5E-37 T 29-03-2018 IPR003781 CoA-binding GO:0048037 MC49_RS11340 50ebfc43a4e885d50c68509fea500b35 137 SMART SM00881 10 104 1.5E-24 T 29-03-2018 IPR003781 CoA-binding GO:0048037 MC49_RS11340 50ebfc43a4e885d50c68509fea500b35 137 Gene3D G3DSA:3.40.50.720 10 134 9.7E-34 T 29-03-2018 MC49_RS16985 502b5de277727ad7f8132178d26dc29c 189 Pfam PF00419 Fimbrial protein 46 189 5.8E-18 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS16985 502b5de277727ad7f8132178d26dc29c 189 SUPERFAMILY SSF49401 44 189 1.34E-28 T 29-03-2018 IPR008966 Adhesion domain MC49_RS16985 502b5de277727ad7f8132178d26dc29c 189 Gene3D G3DSA:2.60.40.1090 43 189 8.9E-33 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS03460 1e8af8ffe4a48ae27b95bb16b7841d6d 128 Gene3D G3DSA:1.10.10.10 3 68 4.4E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS03460 1e8af8ffe4a48ae27b95bb16b7841d6d 128 Pfam PF02316 Mu DNA-binding domain 9 111 8.3E-15 T 29-03-2018 IPR003314 Mu-type HTH domain GO:0003677 MC49_RS03460 1e8af8ffe4a48ae27b95bb16b7841d6d 128 SUPERFAMILY SSF46955 3 63 2.47E-22 T 29-03-2018 IPR009061 Putative DNA-binding domain MC49_RS03460 1e8af8ffe4a48ae27b95bb16b7841d6d 128 ProDom PD060594 TRANSCRIPTION YFED YFEC DNA-BINDING REGULATION NEGATIVE REGULATOR STY2653 ECS3274 STY2652 7 112 0.009 T 29-03-2018 IPR010749 Protein of unknown function DUF1323 MC49_RS15630 d73edfaf28e4001a83b790a3a304057e 269 Pfam PF00005 ABC transporter 31 178 4.7E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS15630 d73edfaf28e4001a83b790a3a304057e 269 SUPERFAMILY SSF52540 3 252 8.04E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS15630 d73edfaf28e4001a83b790a3a304057e 269 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS15630 d73edfaf28e4001a83b790a3a304057e 269 Gene3D G3DSA:3.40.50.300 3 263 5.7E-64 T 29-03-2018 MC49_RS15630 d73edfaf28e4001a83b790a3a304057e 269 SMART SM00382 39 228 1.7E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS12990 c046eb59dd96ff9e3aa2123dcc36d616 212 Gene3D G3DSA:3.40.1800.10 80 165 9.4E-4 T 29-03-2018 MC49_RS12990 c046eb59dd96ff9e3aa2123dcc36d616 212 Pfam PF05766 Bacteriophage Lambda NinG protein 5 210 1.6E-58 T 29-03-2018 IPR008713 Bacteriophage lambda NinG MC49_RS11950 49f3ca8d9b830f6da4ac60147cd61c29 145 Pfam PF04965 Gene 25-like lysozyme 35 123 6.6E-17 T 29-03-2018 IPR007048 GpW/Gp25/anti-adapter protein IraD MC49_RS11950 49f3ca8d9b830f6da4ac60147cd61c29 145 Gene3D G3DSA:3.10.450.40 2 138 9.6E-24 T 29-03-2018 MC49_RS11950 49f3ca8d9b830f6da4ac60147cd61c29 145 SUPERFAMILY SSF160719 32 136 9.15E-19 T 29-03-2018 MC49_RS11950 49f3ca8d9b830f6da4ac60147cd61c29 145 TIGRFAM TIGR03357 VI_zyme: type VI secretion system lysozyme-like protein 14 142 6.6E-36 T 29-03-2018 IPR017737 Type VI secretion system, lysozyme-related protein MC49_RS04355 01029691e3cb9bebdeaa29b0bc66366f 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 308 4.0E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS04355 01029691e3cb9bebdeaa29b0bc66366f 318 SUPERFAMILY SSF161098 27 304 3.16E-34 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS04355 01029691e3cb9bebdeaa29b0bc66366f 318 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 17 311 7.7E-96 T 29-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 MC49_RS04355 01029691e3cb9bebdeaa29b0bc66366f 318 Gene3D G3DSA:1.10.3720.10 11 306 1.4E-32 T 29-03-2018 MC49_RS07710 d71f4530190bc6989dd33fa2a4ad4bb5 259 SUPERFAMILY SSF53213 3 257 1.31E-83 T 29-03-2018 MC49_RS07710 d71f4530190bc6989dd33fa2a4ad4bb5 259 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 21 253 3.6E-30 T 29-03-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 MC49_RS07710 d71f4530190bc6989dd33fa2a4ad4bb5 259 PIRSF PIRSF006157 1 259 8.3E-86 T 29-03-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 MC49_RS07710 d71f4530190bc6989dd33fa2a4ad4bb5 259 Gene3D G3DSA:3.40.830.10 1 259 4.6E-78 T 29-03-2018 MC49_RS16325 223e6e6d165dffc11279d66f9be741e4 463 Gene3D G3DSA:3.20.20.70 7 180 4.7E-4 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS16325 223e6e6d165dffc11279d66f9be741e4 463 Pfam PF16325 Peptidase family U32 C-terminal domain 359 440 3.5E-22 T 29-03-2018 IPR032525 Peptidase family U32, C-terminal MC49_RS16325 223e6e6d165dffc11279d66f9be741e4 463 ProSitePatterns PS01276 Peptidase family U32 signature. 162 180 - T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 MC49_RS16325 223e6e6d165dffc11279d66f9be741e4 463 Pfam PF01136 Peptidase family U32 75 343 5.0E-97 T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 MC49_RS16680 3d0b5248c48cf57757cc918c6a4ec239 335 Pfam PF04960 Glutaminase 50 334 2.4E-106 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 MC49_RS16680 3d0b5248c48cf57757cc918c6a4ec239 335 TIGRFAM TIGR03814 Gln_ase: glutaminase A 40 334 4.9E-107 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 MC49_RS16680 3d0b5248c48cf57757cc918c6a4ec239 335 Gene3D G3DSA:3.40.710.10 28 335 1.9E-111 T 29-03-2018 MC49_RS16680 3d0b5248c48cf57757cc918c6a4ec239 335 Hamap MF_00313 Glutaminase [glsA]. 32 334 41.295 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 MC49_RS16680 3d0b5248c48cf57757cc918c6a4ec239 335 SUPERFAMILY SSF56601 31 334 2.94E-105 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MC49_RS13695 b4f2f3c68634305e36f54c9c0ad24766 230 Pfam PF04352 ProQ/FINO family 8 116 9.9E-42 T 29-03-2018 IPR016103 ProQ/FinO domain MC49_RS13695 b4f2f3c68634305e36f54c9c0ad24766 230 Hamap MF_00749 RNA chaperone ProQ [proQ]. 3 230 28.181 T 29-03-2018 IPR023529 RNA chaperone ProQ GO:0003723|GO:0010608|GO:0033592|GO:0034057 MC49_RS13695 b4f2f3c68634305e36f54c9c0ad24766 230 SMART SM00945 5 119 1.9E-55 T 29-03-2018 IPR016103 ProQ/FinO domain MC49_RS13695 b4f2f3c68634305e36f54c9c0ad24766 230 SUPERFAMILY SSF48657 5 118 4.05E-36 T 29-03-2018 IPR016103 ProQ/FinO domain MC49_RS13695 b4f2f3c68634305e36f54c9c0ad24766 230 Pfam PF17516 ProQ C-terminal domain 180 229 3.3E-22 T 29-03-2018 IPR035236 RNA chaperone ProQ, C-terminal MC49_RS13695 b4f2f3c68634305e36f54c9c0ad24766 230 Gene3D G3DSA:1.10.1710.10 1 121 6.8E-39 T 29-03-2018 IPR016103 ProQ/FinO domain MC49_RS02500 95ed2c155b05dea7f59bd5ce5298c22c 152 Pfam PF09350 Domain of unknown function (DUF1992) 36 102 4.3E-21 T 29-03-2018 IPR018961 DnaJ homologue, subfamily C, member 28, conserved domain MC49_RS13940 e6f78aee6230447a9bfdf739776a566a 300 SMART SM00729 23 247 2.9E-45 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MC49_RS13940 e6f78aee6230447a9bfdf739776a566a 300 Gene3D G3DSA:3.20.20.70 3 298 1.4E-36 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS13940 e6f78aee6230447a9bfdf739776a566a 300 SUPERFAMILY SSF102114 13 259 4.84E-47 T 29-03-2018 MC49_RS13940 e6f78aee6230447a9bfdf739776a566a 300 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 7 298 3.5E-132 T 29-03-2018 IPR005911 Protein YhcC-like GO:0051536 MC49_RS13940 e6f78aee6230447a9bfdf739776a566a 300 Pfam PF04055 Radical SAM superfamily 43 199 9.7E-16 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MC49_RS13940 e6f78aee6230447a9bfdf739776a566a 300 Pfam PF16199 Radical_SAM C-terminal domain 208 279 1.9E-19 T 29-03-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 MC49_RS07050 bfdb61bf3f04f6c2a34e5fd5381b97ba 549 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 7 546 2.6E-191 T 29-03-2018 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 MC49_RS07050 bfdb61bf3f04f6c2a34e5fd5381b97ba 549 Pfam PF00999 Sodium/hydrogen exchanger family 8 421 2.0E-74 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 MC49_RS04395 091e07f27c72fc7d2b1454b360075a22 77 Pfam PF09012 FeoC like transcriptional regulator 3 73 4.3E-17 T 29-03-2018 IPR015102 Transcriptional regulator HTH-type, FeoC MC49_RS04395 091e07f27c72fc7d2b1454b360075a22 77 SUPERFAMILY SSF46785 1 72 2.38E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS04395 091e07f27c72fc7d2b1454b360075a22 77 Gene3D G3DSA:1.10.10.10 1 74 1.4E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS04395 091e07f27c72fc7d2b1454b360075a22 77 Hamap MF_01586 Probable [Fe-S]-dependent transcriptional repressor [feoC]. 1 76 24.175 T 29-03-2018 IPR023732 Probable [Fe-S]-dependent transcriptional repressor MC49_RS11775 34651efef835d760224d88e5a5f575dc 448 Gene3D G3DSA:3.40.50.300 227 441 4.7E-41 T 29-03-2018 MC49_RS11775 34651efef835d760224d88e5a5f575dc 448 Pfam PF00271 Helicase conserved C-terminal domain 238 343 6.6E-27 T 29-03-2018 IPR001650 Helicase, C-terminal MC49_RS11775 34651efef835d760224d88e5a5f575dc 448 SMART SM00490 262 343 8.7E-26 T 29-03-2018 IPR001650 Helicase, C-terminal MC49_RS11775 34651efef835d760224d88e5a5f575dc 448 SUPERFAMILY SSF52540 261 379 3.51E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS11775 34651efef835d760224d88e5a5f575dc 448 SUPERFAMILY SSF52540 41 101 3.51E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS11775 34651efef835d760224d88e5a5f575dc 448 Pfam PF00270 DEAD/DEAH box helicase 28 197 1.0E-45 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MC49_RS11775 34651efef835d760224d88e5a5f575dc 448 SMART SM00487 23 225 3.6E-58 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MC49_RS11775 34651efef835d760224d88e5a5f575dc 448 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 155 163 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site MC49_RS11775 34651efef835d760224d88e5a5f575dc 448 Gene3D G3DSA:3.40.50.300 1 226 1.1E-56 T 29-03-2018 MC49_RS11775 34651efef835d760224d88e5a5f575dc 448 Hamap MF_00967 ATP-dependent RNA helicase SrmB [srmB]. 4 428 47.786 T 29-03-2018 IPR028621 ATP-dependent RNA helicase SrmB GO:0000027|GO:0004004 MC49_RS11775 34651efef835d760224d88e5a5f575dc 448 SUPERFAMILY SSF52540 3 211 4.23E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS12525 7914c103aea801d46a821314bb32b3d2 268 Pfam PF13861 FlgD Tudor-like domain 86 261 7.3E-10 T 29-03-2018 IPR025963 FlgD Tudor-like domain MC49_RS12525 7914c103aea801d46a821314bb32b3d2 268 Pfam PF13860 FlgD Ig-like domain 146 218 7.3E-12 T 29-03-2018 IPR025965 FlgD Ig-like domain MC49_RS12525 7914c103aea801d46a821314bb32b3d2 268 Pfam PF03963 Flagellar hook capping protein - N-terminal region 6 75 3.7E-20 T 29-03-2018 IPR005648 Flagellar hook capping protein MC49_RS15180 536ce9b0abf7bc829c8595b77751e729 104 Pfam PF04972 BON domain 37 104 5.6E-20 T 29-03-2018 IPR007055 BON domain MC49_RS15180 536ce9b0abf7bc829c8595b77751e729 104 SMART SM00749 42 104 9.8E-7 T 29-03-2018 IPR014004 Transport-associated and nodulation domain, bacteria MC49_RS15180 536ce9b0abf7bc829c8595b77751e729 104 Gene3D G3DSA:3.40.190.10 1 102 5.4E-4 T 29-03-2018 MC49_RS07100 f1252e8efc6b0b443bbe4e5ebbbae11a 251 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 16 250 38.669 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 MC49_RS07100 f1252e8efc6b0b443bbe4e5ebbbae11a 251 SUPERFAMILY SSF53335 19 248 7.59E-52 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS07100 f1252e8efc6b0b443bbe4e5ebbbae11a 251 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 36 51 - T 29-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 MC49_RS07100 f1252e8efc6b0b443bbe4e5ebbbae11a 251 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 25 250 3.6E-85 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 MC49_RS07100 f1252e8efc6b0b443bbe4e5ebbbae11a 251 Gene3D G3DSA:3.40.50.150 1 250 1.3E-46 T 29-03-2018 MC49_RS07100 f1252e8efc6b0b443bbe4e5ebbbae11a 251 Pfam PF01209 ubiE/COQ5 methyltransferase family 21 250 5.2E-103 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 MC49_RS07100 f1252e8efc6b0b443bbe4e5ebbbae11a 251 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 158 172 - T 29-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 MC49_RS08960 2b286076fa641ab6a5afd4d81762db24 209 SUPERFAMILY SSF52172 1 125 2.42E-30 T 29-03-2018 IPR011006 CheY-like superfamily MC49_RS08960 2b286076fa641ab6a5afd4d81762db24 209 Gene3D G3DSA:3.40.50.2300 1 125 8.6E-30 T 29-03-2018 MC49_RS08960 2b286076fa641ab6a5afd4d81762db24 209 SUPERFAMILY SSF46894 130 206 1.94E-20 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MC49_RS08960 2b286076fa641ab6a5afd4d81762db24 209 SMART SM00448 2 115 2.3E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS08960 2b286076fa641ab6a5afd4d81762db24 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 145 200 1.1E-18 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS08960 2b286076fa641ab6a5afd4d81762db24 209 ProSitePatterns PS00622 LuxR-type HTH domain signature. 160 187 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS08960 2b286076fa641ab6a5afd4d81762db24 209 Gene3D G3DSA:1.10.10.10 126 209 1.5E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS08960 2b286076fa641ab6a5afd4d81762db24 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 188 1.1E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS08960 2b286076fa641ab6a5afd4d81762db24 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 176 1.1E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS08960 2b286076fa641ab6a5afd4d81762db24 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 146 160 1.1E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS08960 2b286076fa641ab6a5afd4d81762db24 209 Pfam PF00072 Response regulator receiver domain 4 116 4.9E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS08960 2b286076fa641ab6a5afd4d81762db24 209 SMART SM00421 143 200 3.6E-20 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS12460 1ed4c8e2a31937717e93d2d9cbbed485 355 SUPERFAMILY SSF52738 166 349 4.97E-70 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MC49_RS12460 1ed4c8e2a31937717e93d2d9cbbed485 355 Gene3D G3DSA:3.40.50.2300 1 156 8.3E-30 T 29-03-2018 MC49_RS12460 1ed4c8e2a31937717e93d2d9cbbed485 355 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 4 351 40.021 T 29-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MC49_RS12460 1ed4c8e2a31937717e93d2d9cbbed485 355 Pfam PF01339 CheB methylesterase 168 345 5.5E-62 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MC49_RS12460 1ed4c8e2a31937717e93d2d9cbbed485 355 PIRSF PIRSF000876 1 355 9.8E-137 T 29-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MC49_RS12460 1ed4c8e2a31937717e93d2d9cbbed485 355 SUPERFAMILY SSF52172 1 108 1.57E-29 T 29-03-2018 IPR011006 CheY-like superfamily MC49_RS12460 1ed4c8e2a31937717e93d2d9cbbed485 355 Pfam PF00072 Response regulator receiver domain 6 109 3.1E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS12460 1ed4c8e2a31937717e93d2d9cbbed485 355 SMART SM00448 4 116 8.4E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS12460 1ed4c8e2a31937717e93d2d9cbbed485 355 Gene3D G3DSA:3.40.50.180 159 354 3.3E-76 T 29-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MC49_RS04060 48e0f602ac47385b462d2e80e7063897 443 ProSitePatterns PS00756 Protein secY signature 2. 173 190 - T 29-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MC49_RS04060 48e0f602ac47385b462d2e80e7063897 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 370 388 1.7E-99 T 29-03-2018 MC49_RS04060 48e0f602ac47385b462d2e80e7063897 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 272 291 1.7E-99 T 29-03-2018 MC49_RS04060 48e0f602ac47385b462d2e80e7063897 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 315 337 1.7E-99 T 29-03-2018 MC49_RS04060 48e0f602ac47385b462d2e80e7063897 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 402 420 1.7E-99 T 29-03-2018 MC49_RS04060 48e0f602ac47385b462d2e80e7063897 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 154 179 1.7E-99 T 29-03-2018 MC49_RS04060 48e0f602ac47385b462d2e80e7063897 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 23 41 1.7E-99 T 29-03-2018 MC49_RS04060 48e0f602ac47385b462d2e80e7063897 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 75 95 1.7E-99 T 29-03-2018 MC49_RS04060 48e0f602ac47385b462d2e80e7063897 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 116 139 1.7E-99 T 29-03-2018 MC49_RS04060 48e0f602ac47385b462d2e80e7063897 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 180 203 1.7E-99 T 29-03-2018 MC49_RS04060 48e0f602ac47385b462d2e80e7063897 443 Hamap MF_01465 Protein translocase subunit SecY [secY]. 10 433 29.738 T 29-03-2018 IPR026593 Protein translocase subunit SecY MC49_RS04060 48e0f602ac47385b462d2e80e7063897 443 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 20 429 5.2E-140 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MC49_RS04060 48e0f602ac47385b462d2e80e7063897 443 Pfam PF00344 SecY translocase 76 417 4.6E-120 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MC49_RS04060 48e0f602ac47385b462d2e80e7063897 443 ProSitePatterns PS00755 Protein secY signature 1. 76 95 - T 29-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MC49_RS04060 48e0f602ac47385b462d2e80e7063897 443 Gene3D G3DSA:1.10.3370.10 9 439 2.6E-161 T 29-03-2018 MC49_RS04060 48e0f602ac47385b462d2e80e7063897 443 PIRSF PIRSF004557 11 441 9.1E-125 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MC49_RS04060 48e0f602ac47385b462d2e80e7063897 443 SUPERFAMILY SSF103491 16 424 1.31E-133 T 29-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MC49_RS16220 e127c873203a0816ea3a536d0c6f7162 277 Gene3D G3DSA:2.160.20.10 24 276 4.9E-19 T 29-03-2018 IPR012334 Pectin lyase fold MC49_RS16220 e127c873203a0816ea3a536d0c6f7162 277 SUPERFAMILY SSF51126 31 243 1.44E-19 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor MC49_RS16220 e127c873203a0816ea3a536d0c6f7162 277 Pfam PF05860 haemagglutination activity domain 31 126 1.9E-16 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal MC49_RS16220 e127c873203a0816ea3a536d0c6f7162 277 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 56 118 6.4E-14 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal MC49_RS08565 b7b34b9c8a713613a9d3f2d5e297c293 340 SUPERFAMILY SSF53659 3 324 1.77E-79 T 29-03-2018 MC49_RS08565 b7b34b9c8a713613a9d3f2d5e297c293 340 Gene3D G3DSA:3.40.50.10750 140 297 4.1E-56 T 29-03-2018 MC49_RS08565 b7b34b9c8a713613a9d3f2d5e297c293 340 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 17 319 1.3E-95 T 29-03-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MC49_RS08565 b7b34b9c8a713613a9d3f2d5e297c293 340 Pfam PF01515 Phosphate acetyl/butaryl transferase 2 320 1.6E-111 T 29-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MC49_RS08565 b7b34b9c8a713613a9d3f2d5e297c293 340 PIRSF PIRSF000428 1 328 9.3E-105 T 29-03-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MC49_RS16625 f8207f5fc16ef19fdd764ea340d7a0c0 316 Gene3D G3DSA:3.90.226.10 12 286 8.5E-68 T 29-03-2018 MC49_RS16625 f8207f5fc16ef19fdd764ea340d7a0c0 316 SUPERFAMILY SSF52096 25 282 6.53E-85 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MC49_RS16625 f8207f5fc16ef19fdd764ea340d7a0c0 316 Pfam PF01039 Carboxyl transferase domain 105 240 1.1E-15 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 MC49_RS16625 f8207f5fc16ef19fdd764ea340d7a0c0 316 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 129 143 3.2E-36 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MC49_RS16625 f8207f5fc16ef19fdd764ea340d7a0c0 316 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 200 217 3.2E-36 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MC49_RS16625 f8207f5fc16ef19fdd764ea340d7a0c0 316 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 229 240 3.2E-36 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MC49_RS16625 f8207f5fc16ef19fdd764ea340d7a0c0 316 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 163 181 3.2E-36 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MC49_RS16625 f8207f5fc16ef19fdd764ea340d7a0c0 316 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 251 260 3.2E-36 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MC49_RS16625 f8207f5fc16ef19fdd764ea340d7a0c0 316 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 281 37.946 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MC49_RS16625 f8207f5fc16ef19fdd764ea340d7a0c0 316 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 1 282 3.4E-144 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MC49_RS00500 b88063ffd0078f4b6e6cf1f2dc25ada1 287 Pfam PF14559 Tetratricopeptide repeat 127 193 2.3E-16 T 29-03-2018 MC49_RS00500 b88063ffd0078f4b6e6cf1f2dc25ada1 287 Gene3D G3DSA:3.40.30.10 1 114 1.4E-22 T 29-03-2018 MC49_RS00500 b88063ffd0078f4b6e6cf1f2dc25ada1 287 Pfam PF14561 Tetratricopeptide repeat 198 287 2.2E-26 T 29-03-2018 MC49_RS00500 b88063ffd0078f4b6e6cf1f2dc25ada1 287 SUPERFAMILY SSF52833 6 114 3.42E-25 T 29-03-2018 IPR012336 Thioredoxin-like fold MC49_RS00500 b88063ffd0078f4b6e6cf1f2dc25ada1 287 Gene3D G3DSA:1.25.40.10 200 287 3.1E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MC49_RS00500 b88063ffd0078f4b6e6cf1f2dc25ada1 287 SUPERFAMILY SSF48452 107 255 3.16E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MC49_RS00500 b88063ffd0078f4b6e6cf1f2dc25ada1 287 Pfam PF00085 Thioredoxin 11 111 5.7E-13 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 MC49_RS00500 b88063ffd0078f4b6e6cf1f2dc25ada1 287 Gene3D G3DSA:1.25.40.10 116 199 2.8E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MC49_RS10735 718c1575e490c753d4727fafca428687 257 TIGRFAM TIGR02355 moeB: molybdopterin synthase sulfurylase MoeB 14 253 7.4E-120 T 29-03-2018 IPR012730 Molybdopterin synthase sulfurylase MoeB GO:0006777 MetaCyc: PWY-6823 MC49_RS10735 718c1575e490c753d4727fafca428687 257 SUPERFAMILY SSF69572 9 254 6.54E-84 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MC49_RS10735 718c1575e490c753d4727fafca428687 257 Gene3D G3DSA:3.40.50.720 7 255 2.7E-75 T 29-03-2018 MC49_RS10735 718c1575e490c753d4727fafca428687 257 Pfam PF00899 ThiF family 18 251 6.5E-62 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MC49_RS03990 807f22fe985849a5f8c28a00559323fb 368 Pfam PF02481 DNA recombination-mediator protein A 77 276 3.3E-71 T 29-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 MC49_RS03990 807f22fe985849a5f8c28a00559323fb 368 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 71 285 4.7E-76 T 29-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 MC49_RS03990 807f22fe985849a5f8c28a00559323fb 368 SUPERFAMILY SSF102405 81 286 4.81E-39 T 29-03-2018 MC49_RS03990 807f22fe985849a5f8c28a00559323fb 368 Gene3D G3DSA:1.10.10.10 276 367 8.9E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS03990 807f22fe985849a5f8c28a00559323fb 368 Gene3D G3DSA:3.40.50.450 103 262 6.1E-38 T 29-03-2018 MC49_RS06650 30db92dfaf2a49f850d2230a17823b9e 204 Pfam PF01726 LexA DNA binding domain 1 65 6.2E-29 T 29-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 MC49_RS06650 30db92dfaf2a49f850d2230a17823b9e 204 SUPERFAMILY SSF46785 3 69 6.36E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS06650 30db92dfaf2a49f850d2230a17823b9e 204 Hamap MF_00015 LexA repressor [lexA]. 3 201 32.385 T 29-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 MC49_RS06650 30db92dfaf2a49f850d2230a17823b9e 204 SUPERFAMILY SSF51306 78 200 3.49E-37 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MC49_RS06650 30db92dfaf2a49f850d2230a17823b9e 204 TIGRFAM TIGR00498 lexA: repressor LexA 1 201 1.0E-83 T 29-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 MC49_RS06650 30db92dfaf2a49f850d2230a17823b9e 204 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 124 135 7.4E-13 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MC49_RS06650 30db92dfaf2a49f850d2230a17823b9e 204 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 152 164 7.4E-13 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MC49_RS06650 30db92dfaf2a49f850d2230a17823b9e 204 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 113 123 7.4E-13 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MC49_RS06650 30db92dfaf2a49f850d2230a17823b9e 204 Gene3D G3DSA:2.10.109.10 82 201 3.4E-25 T 29-03-2018 MC49_RS06650 30db92dfaf2a49f850d2230a17823b9e 204 Pfam PF00717 Peptidase S24-like 116 181 4.4E-15 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MC49_RS06650 30db92dfaf2a49f850d2230a17823b9e 204 Gene3D G3DSA:1.10.10.10 1 70 3.2E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS11610 6bf22b16512075e49e7c57362a6af6f0 220 Pfam PF12710 haloacid dehalogenase-like hydrolase 14 192 2.4E-24 T 29-03-2018 MC49_RS11610 6bf22b16512075e49e7c57362a6af6f0 220 Gene3D G3DSA:3.40.50.1000 7 199 1.3E-7 T 29-03-2018 IPR023214 HAD-like domain MC49_RS11610 6bf22b16512075e49e7c57362a6af6f0 220 SUPERFAMILY SSF56784 12 202 1.09E-19 T 29-03-2018 IPR023214 HAD-like domain MC49_RS11610 6bf22b16512075e49e7c57362a6af6f0 220 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 13 204 1.1E-37 T 29-03-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like MC49_RS11610 6bf22b16512075e49e7c57362a6af6f0 220 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 12 194 8.8E-27 T 29-03-2018 MC49_RS02110 9a29639de407790af5c0981543f320c5 518 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 455 472 - T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 MC49_RS02110 9a29639de407790af5c0981543f320c5 518 SUPERFAMILY SSF55604 442 515 2.48E-16 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 MC49_RS02110 9a29639de407790af5c0981543f320c5 518 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 414 487 6.7E-15 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 MC49_RS02110 9a29639de407790af5c0981543f320c5 518 Gene3D G3DSA:3.30.1360.60 440 516 7.7E-20 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 MC49_RS02110 9a29639de407790af5c0981543f320c5 518 Pfam PF00367 phosphotransferase system, EIIB 446 477 1.3E-10 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 MC49_RS02110 9a29639de407790af5c0981543f320c5 518 Pfam PF02378 Phosphotransferase system, EIIC 15 356 4.6E-54 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 MC49_RS05710 ce74068e2d95f18faada2d610007232e 217 Gene3D G3DSA:3.40.50.880 1 217 1.1E-44 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MC49_RS05710 ce74068e2d95f18faada2d610007232e 217 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 5 206 34.881 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 MC49_RS05710 ce74068e2d95f18faada2d610007232e 217 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 6 205 1.7E-71 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 MC49_RS05710 ce74068e2d95f18faada2d610007232e 217 Pfam PF00117 Glutamine amidotransferase class-I 11 195 4.0E-19 T 29-03-2018 IPR017926 Glutamine amidotransferase MC49_RS05710 ce74068e2d95f18faada2d610007232e 217 SUPERFAMILY SSF52317 6 208 9.17E-51 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MC49_RS05710 ce74068e2d95f18faada2d610007232e 217 PIRSF PIRSF000495 4 209 1.9E-73 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 MC49_RS01790 db3143bee40acbc61f802b813c478192 156 SMART SM00671 16 51 150.0 T 29-03-2018 IPR006597 Sel1-like repeat MC49_RS01790 db3143bee40acbc61f802b813c478192 156 SMART SM00671 89 124 2.2E-8 T 29-03-2018 IPR006597 Sel1-like repeat MC49_RS01790 db3143bee40acbc61f802b813c478192 156 SMART SM00671 52 88 0.0022 T 29-03-2018 IPR006597 Sel1-like repeat MC49_RS01790 db3143bee40acbc61f802b813c478192 156 Pfam PF08238 Sel1 repeat 37 50 0.19 T 29-03-2018 IPR006597 Sel1-like repeat MC49_RS01790 db3143bee40acbc61f802b813c478192 156 Pfam PF08238 Sel1 repeat 2 15 0.025 T 29-03-2018 IPR006597 Sel1-like repeat MC49_RS01790 db3143bee40acbc61f802b813c478192 156 Pfam PF08238 Sel1 repeat 52 88 4.9E-4 T 29-03-2018 IPR006597 Sel1-like repeat MC49_RS01790 db3143bee40acbc61f802b813c478192 156 Pfam PF08238 Sel1 repeat 90 123 1.2E-5 T 29-03-2018 IPR006597 Sel1-like repeat MC49_RS01790 db3143bee40acbc61f802b813c478192 156 Gene3D G3DSA:2.60.40.1180 84 143 6.5E-11 T 29-03-2018 MC49_RS01790 db3143bee40acbc61f802b813c478192 156 Gene3D G3DSA:2.60.40.1180 34 83 2.7E-10 T 29-03-2018 MC49_RS01790 db3143bee40acbc61f802b813c478192 156 Gene3D G3DSA:2.60.40.1180 1 27 2.7E-4 T 29-03-2018 MC49_RS01790 db3143bee40acbc61f802b813c478192 156 SUPERFAMILY SSF81901 2 132 6.28E-29 T 29-03-2018 MC49_RS08205 a33709438ad0d77550b93902e4920084 223 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 3 223 35.414 T 29-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 MC49_RS08205 a33709438ad0d77550b93902e4920084 223 Gene3D G3DSA:3.20.20.70 27 176 2.5E-12 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS08205 a33709438ad0d77550b93902e4920084 223 TIGRFAM TIGR04322 rSAM_QueE_Ecoli: putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 9 223 4.1E-107 T 29-03-2018 IPR027609 Putative 7-carboxy-7-deazaguanine synthase QueE, Proteobacteria KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 MC49_RS08205 a33709438ad0d77550b93902e4920084 223 PIRSF PIRSF000370 1 223 3.3E-67 T 29-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 MC49_RS08205 a33709438ad0d77550b93902e4920084 223 Pfam PF04055 Radical SAM superfamily 26 132 1.9E-9 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MC49_RS08205 a33709438ad0d77550b93902e4920084 223 SUPERFAMILY SSF102114 23 119 1.83E-6 T 29-03-2018 MC49_RS08205 a33709438ad0d77550b93902e4920084 223 Pfam PF13394 4Fe-4S single cluster domain 24 128 2.4E-11 T 29-03-2018 MC49_RS08595 9973a4dc18fccdbc0c8e57c81e94d36a 421 Pfam PF04346 Ethanolamine utilisation protein, EutH 3 396 2.8E-132 T 29-03-2018 IPR007441 Ethanolamine utilisation protein EutH GO:0016021|GO:0034228|GO:0034229 MC49_RS08595 9973a4dc18fccdbc0c8e57c81e94d36a 421 PIRSF PIRSF019466 1 414 1.5E-119 T 29-03-2018 IPR007441 Ethanolamine utilisation protein EutH GO:0016021|GO:0034228|GO:0034229 MC49_RS07155 263547295b5c6673fe04e5b7bbe213bc 725 SUPERFAMILY SSF48179 495 612 1.96E-24 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MC49_RS07155 263547295b5c6673fe04e5b7bbe213bc 725 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 496 591 4.5E-22 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 MC49_RS07155 263547295b5c6673fe04e5b7bbe213bc 725 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 316 494 5.9E-61 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 MC49_RS07155 263547295b5c6673fe04e5b7bbe213bc 725 Gene3D G3DSA:1.10.1040.10 622 712 1.4E-14 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MC49_RS07155 263547295b5c6673fe04e5b7bbe213bc 725 Gene3D G3DSA:1.10.1040.10 503 592 2.4E-18 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MC49_RS07155 263547295b5c6673fe04e5b7bbe213bc 725 Gene3D G3DSA:3.40.50.720 273 495 1.2E-59 T 29-03-2018 MC49_RS07155 263547295b5c6673fe04e5b7bbe213bc 725 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 208 2.4E-34 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MC49_RS07155 263547295b5c6673fe04e5b7bbe213bc 725 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 493 517 - T 29-03-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 MC49_RS07155 263547295b5c6673fe04e5b7bbe213bc 725 SUPERFAMILY SSF52096 6 303 5.38E-61 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MC49_RS07155 263547295b5c6673fe04e5b7bbe213bc 725 Gene3D G3DSA:3.90.226.10 3 272 6.4E-51 T 29-03-2018 MC49_RS07155 263547295b5c6673fe04e5b7bbe213bc 725 SUPERFAMILY SSF48179 622 714 2.3E-22 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MC49_RS07155 263547295b5c6673fe04e5b7bbe213bc 725 TIGRFAM TIGR02437 FadB: fatty oxidation complex, alpha subunit FadB 1 714 0.0 T 29-03-2018 IPR012799 Fatty oxidation complex, alpha subunit FadB GO:0003857|GO:0004165|GO:0004300|GO:0008692|GO:0009062|GO:0036125|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35+5.3.3.8|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5137|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6837|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-7291|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 MC49_RS07155 263547295b5c6673fe04e5b7bbe213bc 725 SUPERFAMILY SSF51735 315 495 8.18E-57 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS06315 e9c388b44a3186b883b889714d6db169 286 Gene3D G3DSA:1.10.10.10 1 106 4.2E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS06315 e9c388b44a3186b883b889714d6db169 286 Pfam PF01380 SIS domain 133 260 6.2E-24 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MC49_RS06315 e9c388b44a3186b883b889714d6db169 286 SUPERFAMILY SSF53697 103 275 1.14E-40 T 29-03-2018 MC49_RS06315 e9c388b44a3186b883b889714d6db169 286 Gene3D G3DSA:3.40.50.10490 107 286 4.6E-37 T 29-03-2018 MC49_RS06315 e9c388b44a3186b883b889714d6db169 286 SUPERFAMILY SSF46689 1 77 8.51E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS06315 e9c388b44a3186b883b889714d6db169 286 Pfam PF01418 Helix-turn-helix domain, rpiR family 1 74 9.0E-23 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 MC49_RS15960 741a84bbe143ca3e177eaa1e0a08ed79 327 SUPERFAMILY SSF46589 14 99 3.56E-22 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 MC49_RS15960 741a84bbe143ca3e177eaa1e0a08ed79 327 SUPERFAMILY SSF55681 92 327 4.06E-82 T 29-03-2018 MC49_RS15960 741a84bbe143ca3e177eaa1e0a08ed79 327 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 19 87 6.6E-28 T 29-03-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 MC49_RS15960 741a84bbe143ca3e177eaa1e0a08ed79 327 Gene3D G3DSA:3.30.930.10 7 327 2.8E-89 T 29-03-2018 MC49_RS15960 741a84bbe143ca3e177eaa1e0a08ed79 327 Pfam PF01409 tRNA synthetases class II core domain (F) 92 326 7.0E-107 T 29-03-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 MC49_RS15960 741a84bbe143ca3e177eaa1e0a08ed79 327 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 8 326 49.551 T 29-03-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 MC49_RS15960 741a84bbe143ca3e177eaa1e0a08ed79 327 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 39 327 9.4E-117 T 29-03-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 MC49_RS02375 dd2c4b3dce7857240b7a43b89fe6e624 167 SUPERFAMILY SSF49401 43 166 8.08E-14 T 29-03-2018 IPR008966 Adhesion domain MC49_RS02375 dd2c4b3dce7857240b7a43b89fe6e624 167 Pfam PF00419 Fimbrial protein 38 166 8.5E-10 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS02375 dd2c4b3dce7857240b7a43b89fe6e624 167 Gene3D G3DSA:2.60.40.1090 43 166 4.1E-11 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS18670 a656cd97a5f90b7a6ede529b38a93ffb 457 Pfam PF08245 Mur ligase middle domain 110 299 5.6E-46 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MC49_RS18670 a656cd97a5f90b7a6ede529b38a93ffb 457 Gene3D G3DSA:3.40.1190.10 92 315 4.5E-59 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MC49_RS18670 a656cd97a5f90b7a6ede529b38a93ffb 457 SUPERFAMILY SSF63418 1 99 1.06E-22 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MC49_RS18670 a656cd97a5f90b7a6ede529b38a93ffb 457 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 33 451 1.7E-135 T 29-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MC49_RS18670 a656cd97a5f90b7a6ede529b38a93ffb 457 Gene3D G3DSA:3.40.1390.10 2 91 5.4E-26 T 29-03-2018 MC49_RS18670 a656cd97a5f90b7a6ede529b38a93ffb 457 SUPERFAMILY SSF53623 104 315 6.93E-55 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MC49_RS18670 a656cd97a5f90b7a6ede529b38a93ffb 457 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 452 32.409 T 29-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MC49_RS18670 a656cd97a5f90b7a6ede529b38a93ffb 457 Pfam PF01225 Mur ligase family, catalytic domain 28 77 2.0E-9 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MC49_RS18670 a656cd97a5f90b7a6ede529b38a93ffb 457 Pfam PF02875 Mur ligase family, glutamate ligase domain 319 397 2.4E-10 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MC49_RS18670 a656cd97a5f90b7a6ede529b38a93ffb 457 Gene3D G3DSA:3.90.190.20 318 456 2.6E-35 T 29-03-2018 MC49_RS18670 a656cd97a5f90b7a6ede529b38a93ffb 457 SUPERFAMILY SSF53244 319 451 1.28E-33 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MC49_RS14675 c3f896d0087b73c8b09f3fe6f0b879ca 216 SUPERFAMILY SSF55729 130 191 1.92E-15 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS14675 c3f896d0087b73c8b09f3fe6f0b879ca 216 SUPERFAMILY SSF55729 13 77 1.92E-15 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS14675 c3f896d0087b73c8b09f3fe6f0b879ca 216 Pfam PF00583 Acetyltransferase (GNAT) family 31 183 6.7E-7 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MC49_RS14675 c3f896d0087b73c8b09f3fe6f0b879ca 216 Gene3D G3DSA:3.40.630.30 11 214 2.5E-16 T 29-03-2018 MC49_RS09425 d3f63fba936e5670e4e8407dda3e3f72 272 SUPERFAMILY SSF53167 4 271 1.7E-95 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MC49_RS09425 d3f63fba936e5670e4e8407dda3e3f72 272 Pfam PF01048 Phosphorylase superfamily 23 269 8.4E-56 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MC49_RS09425 d3f63fba936e5670e4e8407dda3e3f72 272 PIRSF PIRSF000477 2 272 2.6E-107 T 29-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 MC49_RS09425 d3f63fba936e5670e4e8407dda3e3f72 272 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 24 269 9.4E-105 T 29-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 MC49_RS09425 d3f63fba936e5670e4e8407dda3e3f72 272 Gene3D G3DSA:3.40.50.1580 1 272 3.5E-70 T 29-03-2018 MC49_RS09425 d3f63fba936e5670e4e8407dda3e3f72 272 TIGRFAM TIGR01700 PNPH: purine nucleoside phosphorylase I, inosine and guanosine-specific 24 269 1.3E-105 T 29-03-2018 IPR011270 Purine nucleoside phosphorylase I, inosine/guanosine-specific GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 MC49_RS11790 db5b7b019653b60e9370a28c36196459 192 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 183 1.1E-30 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS11790 db5b7b019653b60e9370a28c36196459 192 SUPERFAMILY SSF88659 122 183 3.92E-18 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS11790 db5b7b019653b60e9370a28c36196459 192 TIGRFAM TIGR02939 RpoE_Sigma70: RNA polymerase sigma factor RpoE 1 189 6.5E-99 T 29-03-2018 IPR014286 RNA polymerase sigma-70 RpoE type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS11790 db5b7b019653b60e9370a28c36196459 192 Pfam PF04542 Sigma-70 region 2 25 91 7.7E-16 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS11790 db5b7b019653b60e9370a28c36196459 192 Gene3D G3DSA:1.10.1740.10 1 114 2.8E-29 T 29-03-2018 MC49_RS11790 db5b7b019653b60e9370a28c36196459 192 Pfam PF08281 Sigma-70, region 4 133 180 2.1E-18 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS11790 db5b7b019653b60e9370a28c36196459 192 SUPERFAMILY SSF88946 2 104 1.24E-29 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS11790 db5b7b019653b60e9370a28c36196459 192 Gene3D G3DSA:1.10.10.10 115 187 2.2E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS11790 db5b7b019653b60e9370a28c36196459 192 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 46 77 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS05435 6264ac6458ec97f17146a297099fb38b 308 SUPERFAMILY SSF144020 27 307 7.19E-94 T 29-03-2018 IPR024064 FdhE-like MC49_RS05435 6264ac6458ec97f17146a297099fb38b 308 Gene3D G3DSA:3.90.1670.10 25 308 8.9E-95 T 29-03-2018 IPR024064 FdhE-like MC49_RS05435 6264ac6458ec97f17146a297099fb38b 308 PIRSF PIRSF018296 1 308 5.7E-126 T 29-03-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 MC49_RS05435 6264ac6458ec97f17146a297099fb38b 308 Hamap MF_00611 Protein FdhE [fdhE]. 3 307 46.014 T 29-03-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 MC49_RS05435 6264ac6458ec97f17146a297099fb38b 308 TIGRFAM TIGR01562 FdhE: formate dehydrogenase accessory protein FdhE 2 306 5.6E-114 T 29-03-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 MC49_RS05435 6264ac6458ec97f17146a297099fb38b 308 Pfam PF04216 Protein involved in formate dehydrogenase formation 24 305 6.3E-112 T 29-03-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 MC49_RS09815 63fd5670ccc23d566fd6453b4d2760ec 875 Pfam PF02272 DHHA1 domain 733 871 1.8E-27 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 MC49_RS09815 63fd5670ccc23d566fd6453b4d2760ec 875 SUPERFAMILY SSF101353 256 465 4.71E-61 T 29-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 MC49_RS09815 63fd5670ccc23d566fd6453b4d2760ec 875 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 7 854 0.0 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MC49_RS09815 63fd5670ccc23d566fd6453b4d2760ec 875 PRINTS PR00980 Alanyl-tRNA synthetase signature 306 319 1.0E-32 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MC49_RS09815 63fd5670ccc23d566fd6453b4d2760ec 875 PRINTS PR00980 Alanyl-tRNA synthetase signature 236 249 1.0E-32 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MC49_RS09815 63fd5670ccc23d566fd6453b4d2760ec 875 PRINTS PR00980 Alanyl-tRNA synthetase signature 76 87 1.0E-32 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MC49_RS09815 63fd5670ccc23d566fd6453b4d2760ec 875 PRINTS PR00980 Alanyl-tRNA synthetase signature 282 298 1.0E-32 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MC49_RS09815 63fd5670ccc23d566fd6453b4d2760ec 875 PRINTS PR00980 Alanyl-tRNA synthetase signature 209 220 1.0E-32 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MC49_RS09815 63fd5670ccc23d566fd6453b4d2760ec 875 SMART SM00863 653 696 2.7E-21 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 MC49_RS09815 63fd5670ccc23d566fd6453b4d2760ec 875 Gene3D G3DSA:3.30.930.10 2 252 3.5E-117 T 29-03-2018 MC49_RS09815 63fd5670ccc23d566fd6453b4d2760ec 875 Gene3D G3DSA:3.30.980.10 553 713 3.1E-47 T 29-03-2018 MC49_RS09815 63fd5670ccc23d566fd6453b4d2760ec 875 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 653 696 1.0E-17 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 MC49_RS09815 63fd5670ccc23d566fd6453b4d2760ec 875 SUPERFAMILY SSF50447 456 552 2.86E-18 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain MC49_RS09815 63fd5670ccc23d566fd6453b4d2760ec 875 Pfam PF01411 tRNA synthetases class II (A) 7 556 3.2E-235 T 29-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 MC49_RS09815 63fd5670ccc23d566fd6453b4d2760ec 875 SUPERFAMILY SSF55186 552 709 1.57E-52 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 MC49_RS09815 63fd5670ccc23d566fd6453b4d2760ec 875 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 875 204.443 T 29-03-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 MC49_RS09815 63fd5670ccc23d566fd6453b4d2760ec 875 SUPERFAMILY SSF55681 4 255 5.72E-108 T 29-03-2018 MC49_RS08550 3f3bda4f9a67eb2b56700fc117b93f64 148 SUPERFAMILY SSF52540 3 143 6.86E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS08550 3f3bda4f9a67eb2b56700fc117b93f64 148 PIRSF PIRSF036409 1 148 5.5E-42 T 29-03-2018 IPR012381 Ethanolamine/propanediol utilisation protein, EutP/PduV GO:0005524|GO:0006576 MC49_RS08550 3f3bda4f9a67eb2b56700fc117b93f64 148 Pfam PF10662 Ethanolamine utilisation - propanediol utilisation 1 142 9.9E-27 T 29-03-2018 IPR012381 Ethanolamine/propanediol utilisation protein, EutP/PduV GO:0005524|GO:0006576 MC49_RS08550 3f3bda4f9a67eb2b56700fc117b93f64 148 Gene3D G3DSA:3.40.50.300 2 143 1.5E-12 T 29-03-2018 MC49_RS08550 3f3bda4f9a67eb2b56700fc117b93f64 148 TIGRFAM TIGR02528 EutP: ethanolamine utilization protein, EutP 2 143 2.4E-41 T 29-03-2018 IPR012381 Ethanolamine/propanediol utilisation protein, EutP/PduV GO:0005524|GO:0006576 MC49_RS00985 350074eedf2968a81af2ba56349d865e 273 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 10 264 2.5E-100 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 MC49_RS00985 350074eedf2968a81af2ba56349d865e 273 Pfam PF02673 Bacitracin resistance protein BacA 10 265 3.9E-86 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 MC49_RS00985 350074eedf2968a81af2ba56349d865e 273 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 5 271 18.671 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 MC49_RS01260 94a4beba39275b4a2b3777c6cbbb2ff3 399 Gene3D G3DSA:1.10.443.10 202 388 1.9E-28 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MC49_RS01260 94a4beba39275b4a2b3777c6cbbb2ff3 399 SUPERFAMILY SSF56349 98 378 1.56E-50 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MC49_RS01260 94a4beba39275b4a2b3777c6cbbb2ff3 399 Gene3D G3DSA:1.10.150.130 88 201 2.0E-18 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal MC49_RS01260 94a4beba39275b4a2b3777c6cbbb2ff3 399 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 99 150 2.1E-8 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 MC49_RS01260 94a4beba39275b4a2b3777c6cbbb2ff3 399 Pfam PF13356 Arm DNA-binding domain 6 93 3.0E-15 T 29-03-2018 IPR025166 Integrase, DNA-binding domain MC49_RS01260 94a4beba39275b4a2b3777c6cbbb2ff3 399 Pfam PF00589 Phage integrase family 230 371 1.0E-14 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MC49_RS04120 931c4dea059e039ae30e7ec6a5ba8d9d 63 SUPERFAMILY SSF46561 1 61 6.41E-22 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04120 931c4dea059e039ae30e7ec6a5ba8d9d 63 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 29-03-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04120 931c4dea059e039ae30e7ec6a5ba8d9d 63 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 2.0E-22 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04120 931c4dea059e039ae30e7ec6a5ba8d9d 63 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 18.676 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04120 931c4dea059e039ae30e7ec6a5ba8d9d 63 Gene3D G3DSA:1.10.287.310 1 63 4.7E-23 T 29-03-2018 MC49_RS04120 931c4dea059e039ae30e7ec6a5ba8d9d 63 Pfam PF00831 Ribosomal L29 protein 4 60 6.4E-23 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS09210 e81bd57070a18e6094accee80cb52dbc 251 PIRSF PIRSF005457 1 251 8.5E-90 T 29-03-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 MC49_RS09210 e81bd57070a18e6094accee80cb52dbc 251 Hamap MF_01374 Hydroxyacylglutathione hydrolase [gloB]. 1 251 43.938 T 29-03-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 MC49_RS09210 e81bd57070a18e6094accee80cb52dbc 251 Pfam PF00753 Metallo-beta-lactamase superfamily 13 165 2.8E-16 T 29-03-2018 IPR001279 Metallo-beta-lactamase MC49_RS09210 e81bd57070a18e6094accee80cb52dbc 251 SMART SM00849 11 165 2.5E-37 T 29-03-2018 IPR001279 Metallo-beta-lactamase MC49_RS09210 e81bd57070a18e6094accee80cb52dbc 251 Gene3D G3DSA:3.60.15.10 1 251 1.9E-69 T 29-03-2018 IPR001279 Metallo-beta-lactamase MC49_RS09210 e81bd57070a18e6094accee80cb52dbc 251 TIGRFAM TIGR03413 GSH_gloB: hydroxyacylglutathione hydrolase 4 251 3.6E-101 T 29-03-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 MC49_RS09210 e81bd57070a18e6094accee80cb52dbc 251 Pfam PF16123 Hydroxyacylglutathione hydrolase C-terminus 166 251 2.3E-23 T 29-03-2018 IPR032282 Hydroxyacylglutathione hydrolase, C-terminal domain KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 MC49_RS09210 e81bd57070a18e6094accee80cb52dbc 251 SUPERFAMILY SSF56281 1 251 2.23E-70 T 29-03-2018 IPR001279 Metallo-beta-lactamase MC49_RS06160 05014a6e827ca0321e48ec754aa38469 342 Gene3D G3DSA:3.40.710.10 11 339 8.7E-60 T 29-03-2018 MC49_RS06160 05014a6e827ca0321e48ec754aa38469 342 SUPERFAMILY SSF56601 35 329 1.36E-57 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MC49_RS06160 05014a6e827ca0321e48ec754aa38469 342 Pfam PF00144 Beta-lactamase 37 324 4.3E-46 T 29-03-2018 IPR001466 Beta-lactamase-related MC49_RS10135 df6d3814b820deb604b7a9754ed74802 239 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 132 160 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MC49_RS10135 df6d3814b820deb604b7a9754ed74802 239 SUPERFAMILY SSF51735 3 227 3.61E-54 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS10135 df6d3814b820deb604b7a9754ed74802 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 4.1E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS10135 df6d3814b820deb604b7a9754ed74802 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 4.1E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS10135 df6d3814b820deb604b7a9754ed74802 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 4.1E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS10135 df6d3814b820deb604b7a9754ed74802 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 7.5E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS10135 df6d3814b820deb604b7a9754ed74802 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 7.5E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS10135 df6d3814b820deb604b7a9754ed74802 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 7.5E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS10135 df6d3814b820deb604b7a9754ed74802 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 7.5E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS10135 df6d3814b820deb604b7a9754ed74802 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 7.5E-27 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS10135 df6d3814b820deb604b7a9754ed74802 239 Gene3D G3DSA:3.40.50.720 1 233 1.7E-51 T 29-03-2018 MC49_RS10135 df6d3814b820deb604b7a9754ed74802 239 Pfam PF00106 short chain dehydrogenase 3 188 5.7E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS08435 2e2c0c271e8546b7be074a031545b954 203 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 4 194 6.5E-57 T 29-03-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 MC49_RS08435 2e2c0c271e8546b7be074a031545b954 203 Gene3D G3DSA:3.30.950.10 111 202 8.0E-21 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MC49_RS08435 2e2c0c271e8546b7be074a031545b954 203 Gene3D G3DSA:3.40.1010.10 1 110 2.0E-21 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MC49_RS08435 2e2c0c271e8546b7be074a031545b954 203 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 1 180 2.2E-28 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MC49_RS08435 2e2c0c271e8546b7be074a031545b954 203 SUPERFAMILY SSF53790 1 192 3.66E-40 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MC49_RS10690 aeca5df912159d33a4519af3641d28a6 230 SUPERFAMILY SSF49354 16 142 5.49E-36 T 29-03-2018 IPR008962 PapD-like MC49_RS10690 aeca5df912159d33a4519af3641d28a6 230 ProSitePatterns PS00635 Gram-negative pili assembly chaperone signature. 95 112 - T 29-03-2018 IPR018046 Pili assembly chaperone, conserved site MC49_RS10690 aeca5df912159d33a4519af3641d28a6 230 Gene3D G3DSA:2.60.40.10 144 230 1.8E-16 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS10690 aeca5df912159d33a4519af3641d28a6 230 PRINTS PR00969 Pili chaperone signature 67 88 3.5E-29 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS10690 aeca5df912159d33a4519af3641d28a6 230 PRINTS PR00969 Pili chaperone signature 21 30 3.5E-29 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS10690 aeca5df912159d33a4519af3641d28a6 230 PRINTS PR00969 Pili chaperone signature 124 139 3.5E-29 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS10690 aeca5df912159d33a4519af3641d28a6 230 PRINTS PR00969 Pili chaperone signature 158 173 3.5E-29 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS10690 aeca5df912159d33a4519af3641d28a6 230 PRINTS PR00969 Pili chaperone signature 96 113 3.5E-29 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS10690 aeca5df912159d33a4519af3641d28a6 230 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 20 142 1.8E-36 T 29-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 MC49_RS10690 aeca5df912159d33a4519af3641d28a6 230 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 163 223 1.9E-13 T 29-03-2018 IPR016148 Pili assembly chaperone, C-terminal MC49_RS10690 aeca5df912159d33a4519af3641d28a6 230 SUPERFAMILY SSF49584 136 226 7.19E-16 T 29-03-2018 IPR016148 Pili assembly chaperone, C-terminal MC49_RS10690 aeca5df912159d33a4519af3641d28a6 230 Gene3D G3DSA:2.60.40.10 20 143 2.6E-31 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS04970 54ce825026acc9847f8866e57b6a380c 106 SUPERFAMILY SSF54909 1 100 3.8E-24 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel MC49_RS04970 54ce825026acc9847f8866e57b6a380c 106 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 76 1.3E-13 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain MC49_RS04970 54ce825026acc9847f8866e57b6a380c 106 Gene3D G3DSA:3.30.70.100 1 94 6.9E-18 T 29-03-2018 MC49_RS06400 68fe28887d932d796192aaa6881fbff5 181 SMART SM00739 127 154 1.0E-6 T 29-03-2018 IPR005824 KOW MC49_RS06400 68fe28887d932d796192aaa6881fbff5 181 SMART SM00738 6 115 4.0E-47 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MC49_RS06400 68fe28887d932d796192aaa6881fbff5 181 Pfam PF02357 Transcription termination factor nusG 7 112 4.4E-28 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MC49_RS06400 68fe28887d932d796192aaa6881fbff5 181 SUPERFAMILY SSF82679 6 116 3.01E-40 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MC49_RS06400 68fe28887d932d796192aaa6881fbff5 181 Gene3D G3DSA:3.30.70.940 6 119 2.5E-42 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MC49_RS06400 68fe28887d932d796192aaa6881fbff5 181 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 9 180 9.2E-72 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MC49_RS06400 68fe28887d932d796192aaa6881fbff5 181 Pfam PF00467 KOW motif 130 162 5.4E-8 T 29-03-2018 IPR005824 KOW MC49_RS06400 68fe28887d932d796192aaa6881fbff5 181 PRINTS PR00338 Transcription termination factor NUSG signature 61 73 1.9E-21 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MC49_RS06400 68fe28887d932d796192aaa6881fbff5 181 PRINTS PR00338 Transcription termination factor NUSG signature 139 154 1.9E-21 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MC49_RS06400 68fe28887d932d796192aaa6881fbff5 181 PRINTS PR00338 Transcription termination factor NUSG signature 157 173 1.9E-21 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MC49_RS06400 68fe28887d932d796192aaa6881fbff5 181 Gene3D G3DSA:2.30.30.30 122 180 8.5E-22 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 MC49_RS06400 68fe28887d932d796192aaa6881fbff5 181 ProSitePatterns PS01014 Transcription termination factor nusG signature. 164 173 - T 29-03-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site MC49_RS06400 68fe28887d932d796192aaa6881fbff5 181 SUPERFAMILY SSF50104 125 180 7.02E-20 T 29-03-2018 IPR008991 Translation protein SH3-like domain MC49_RS06400 68fe28887d932d796192aaa6881fbff5 181 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 6 181 25.411 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MC49_RS08905 cff39579c93cd9d901e590b2d3247dd1 275 Gene3D G3DSA:1.20.5.460 252 273 1.1E-12 T 29-03-2018 MC49_RS08905 cff39579c93cd9d901e590b2d3247dd1 275 SUPERFAMILY SSF51621 3 196 2.92E-84 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MC49_RS08905 cff39579c93cd9d901e590b2d3247dd1 275 PIRSF PIRSF034452 1 275 2.9E-161 T 29-03-2018 IPR009215 TIM-barrel domain, IGPS-like MC49_RS08905 cff39579c93cd9d901e590b2d3247dd1 275 Pfam PF09370 Phosphoenolpyruvate hydrolase-like 8 273 1.7E-135 T 29-03-2018 IPR009215 TIM-barrel domain, IGPS-like MC49_RS08905 cff39579c93cd9d901e590b2d3247dd1 275 Gene3D G3DSA:3.20.20.70 3 251 3.7E-129 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS07950 39feee48770f743e6751a81a480dfa68 308 SUPERFAMILY SSF46785 3 87 4.9E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS07950 39feee48770f743e6751a81a480dfa68 308 Gene3D G3DSA:1.10.10.10 4 91 1.0E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS07950 39feee48770f743e6751a81a480dfa68 308 Gene3D G3DSA:3.40.190.10 178 264 6.8E-22 T 29-03-2018 MC49_RS07950 39feee48770f743e6751a81a480dfa68 308 Gene3D G3DSA:3.40.190.10 92 177 2.6E-16 T 29-03-2018 MC49_RS07950 39feee48770f743e6751a81a480dfa68 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.8E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS07950 39feee48770f743e6751a81a480dfa68 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.8E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS07950 39feee48770f743e6751a81a480dfa68 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.8E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS07950 39feee48770f743e6751a81a480dfa68 308 SUPERFAMILY SSF53850 93 298 1.46E-42 T 29-03-2018 MC49_RS07950 39feee48770f743e6751a81a480dfa68 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 6.7E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS07950 39feee48770f743e6751a81a480dfa68 308 Pfam PF03466 LysR substrate binding domain 91 293 1.7E-40 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS14860 61dece2f87ad3d6c6385d427edaed40c 436 SUPERFAMILY SSF110296 371 391 4.97E-10 T 29-03-2018 MC49_RS14860 61dece2f87ad3d6c6385d427edaed40c 436 SUPERFAMILY SSF110296 185 271 4.97E-10 T 29-03-2018 MC49_RS14860 61dece2f87ad3d6c6385d427edaed40c 436 Gene3D G3DSA:2.120.10.10 160 299 5.0E-10 T 29-03-2018 MC49_RS14860 61dece2f87ad3d6c6385d427edaed40c 436 Gene3D G3DSA:2.120.10.10 300 428 0.018 T 29-03-2018 MC49_RS14240 a36b9a08ca0c25edb2569e39586035a3 270 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 2 268 2.0E-112 T 29-03-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 MC49_RS14240 a36b9a08ca0c25edb2569e39586035a3 270 Gene3D G3DSA:3.40.50.300 1 259 5.2E-54 T 29-03-2018 MC49_RS14240 a36b9a08ca0c25edb2569e39586035a3 270 Pfam PF13614 AAA domain 3 160 5.8E-20 T 29-03-2018 IPR025669 AAA domain MC49_RS14240 a36b9a08ca0c25edb2569e39586035a3 270 SUPERFAMILY SSF52540 1 268 1.18E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS14240 a36b9a08ca0c25edb2569e39586035a3 270 PIRSF PIRSF003092 1 270 4.9E-99 T 29-03-2018 IPR025501 ATP binding protein MinD MC49_RS02600 1472bbaaff208d74dff0abb0a5648ed5 353 SUPERFAMILY SSF58104 80 239 9.02E-27 T 29-03-2018 MC49_RS02600 1472bbaaff208d74dff0abb0a5648ed5 353 Gene3D G3DSA:1.10.287.950 60 276 1.1E-22 T 29-03-2018 MC49_RS02600 1472bbaaff208d74dff0abb0a5648ed5 353 Pfam PF13682 Chemoreceptor zinc-binding domain 251 314 5.0E-15 T 29-03-2018 IPR025991 Chemoreceptor zinc-binding domain MC49_RS02600 1472bbaaff208d74dff0abb0a5648ed5 353 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 102 238 4.9E-17 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MC49_RS00470 9919c2ba8942e692e02d7f0974a2d530 356 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 3 325 33.017 T 29-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 MC49_RS00470 9919c2ba8942e692e02d7f0974a2d530 356 SUPERFAMILY SSF56059 79 274 2.12E-55 T 29-03-2018 MC49_RS00470 9919c2ba8942e692e02d7f0974a2d530 356 Gene3D G3DSA:3.30.470.20 156 340 1.0E-33 T 29-03-2018 MC49_RS00470 9919c2ba8942e692e02d7f0974a2d530 356 Gene3D G3DSA:3.30.1490.20 94 155 3.1E-12 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MC49_RS00470 9919c2ba8942e692e02d7f0974a2d530 356 SUPERFAMILY SSF51246 278 350 5.65E-20 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MC49_RS00470 9919c2ba8942e692e02d7f0974a2d530 356 SUPERFAMILY SSF52440 2 74 5.9E-16 T 29-03-2018 IPR016185 Pre-ATP-grasp domain MC49_RS00470 9919c2ba8942e692e02d7f0974a2d530 356 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 4 329 1.4E-107 T 29-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 MC49_RS00470 9919c2ba8942e692e02d7f0974a2d530 356 Pfam PF02222 ATP-grasp domain 88 254 2.6E-50 T 29-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type MC49_RS00470 9919c2ba8942e692e02d7f0974a2d530 356 Gene3D G3DSA:3.40.50.20 1 69 8.5E-16 T 29-03-2018 MC49_RS02540 81c4ae012e5ca82f3f8e4ee564dbd58b 472 PIRSF PIRSF016636 1 472 1.6E-127 T 29-03-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB MC49_RS02540 81c4ae012e5ca82f3f8e4ee564dbd58b 472 PIRSF PIRSF500217 1 472 1.0E-125 T 29-03-2018 IPR028362 Alginate O-acetyltransferase AlgI GO:0042121 MC49_RS02540 81c4ae012e5ca82f3f8e4ee564dbd58b 472 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 55 341 2.6E-18 T 29-03-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT MC49_RS13930 d559a3ef4bb471d49415b9786ab9ad2e 268 Gene3D G3DSA:1.25.40.10 29 262 4.8E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MC49_RS13930 d559a3ef4bb471d49415b9786ab9ad2e 268 Pfam PF13369 Transglutaminase-like superfamily 33 183 1.4E-37 T 29-03-2018 IPR032698 Protein SirB1, N-terminal Reactome: R-HSA-8951664|Reactome: R-HSA-983168 MC49_RS13930 d559a3ef4bb471d49415b9786ab9ad2e 268 Pfam PF13371 Tetratricopeptide repeat 186 257 1.4E-25 T 29-03-2018 MC49_RS05180 528a1ee2fdd0b10cf988cbc730ee7add 141 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 6 85 1.5E-27 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05180 528a1ee2fdd0b10cf988cbc730ee7add 141 SUPERFAMILY SSF51344 4 87 4.32E-23 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05180 528a1ee2fdd0b10cf988cbc730ee7add 141 SUPERFAMILY SSF46604 89 136 4.71E-12 T 29-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05180 528a1ee2fdd0b10cf988cbc730ee7add 141 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 5 133 3.0E-43 T 29-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05180 528a1ee2fdd0b10cf988cbc730ee7add 141 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 11 91 3.0E-35 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05180 528a1ee2fdd0b10cf988cbc730ee7add 141 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 4 132 20.726 T 29-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05180 528a1ee2fdd0b10cf988cbc730ee7add 141 Gene3D G3DSA:2.60.15.10 1 91 6.5E-28 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05180 528a1ee2fdd0b10cf988cbc730ee7add 141 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 90 133 2.8E-10 T 29-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05180 528a1ee2fdd0b10cf988cbc730ee7add 141 Gene3D G3DSA:1.20.5.440 92 132 1.3E-10 T 29-03-2018 MC49_RS02545 b19509ce288d2f326b723f7e8859374c 396 Gene3D G3DSA:3.40.50.1110 152 368 1.1E-18 T 29-03-2018 MC49_RS02545 b19509ce288d2f326b723f7e8859374c 396 Pfam PF04311 Protein of unknown function (DUF459) 144 366 6.0E-15 T 29-03-2018 IPR007407 Protein of unknown function DUF459 MC49_RS02545 b19509ce288d2f326b723f7e8859374c 396 SUPERFAMILY SSF52266 163 367 1.98E-22 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain MC49_RS11755 1ae2f50254af3a46d5abb53d4c277c2b 192 Pfam PF01025 GrpE 25 192 1.6E-50 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MC49_RS11755 1ae2f50254af3a46d5abb53d4c277c2b 192 PRINTS PR00773 GrpE protein signature 144 159 1.7E-26 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MC49_RS11755 1ae2f50254af3a46d5abb53d4c277c2b 192 PRINTS PR00773 GrpE protein signature 89 104 1.7E-26 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MC49_RS11755 1ae2f50254af3a46d5abb53d4c277c2b 192 PRINTS PR00773 GrpE protein signature 171 190 1.7E-26 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MC49_RS11755 1ae2f50254af3a46d5abb53d4c277c2b 192 PRINTS PR00773 GrpE protein signature 61 77 1.7E-26 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MC49_RS11755 1ae2f50254af3a46d5abb53d4c277c2b 192 Gene3D G3DSA:3.90.20.20 3 135 1.5E-28 T 29-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 MC49_RS11755 1ae2f50254af3a46d5abb53d4c277c2b 192 SUPERFAMILY SSF58014 46 136 1.06E-26 T 29-03-2018 MC49_RS11755 1ae2f50254af3a46d5abb53d4c277c2b 192 Gene3D G3DSA:2.30.22.10 136 192 9.7E-21 T 29-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 MC49_RS11755 1ae2f50254af3a46d5abb53d4c277c2b 192 ProSitePatterns PS01071 grpE protein signature. 147 190 - T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MC49_RS11755 1ae2f50254af3a46d5abb53d4c277c2b 192 SUPERFAMILY SSF51064 137 192 3.92E-18 T 29-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 MC49_RS11755 1ae2f50254af3a46d5abb53d4c277c2b 192 Hamap MF_01151 Protein GrpE [grpE]. 2 192 21.322 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MC49_RS06435 f52c861007d9344e1d25d602ba78adc5 437 Pfam PF01522 Polysaccharide deacetylase 245 385 1.2E-22 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 MC49_RS06435 f52c861007d9344e1d25d602ba78adc5 437 SUPERFAMILY SSF88713 209 408 7.89E-33 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MC49_RS06435 f52c861007d9344e1d25d602ba78adc5 437 Gene3D G3DSA:3.20.20.370 185 430 3.1E-39 T 29-03-2018 MC49_RS05335 625affeffd7af87ea9026ec9bb272630 465 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 374 442 1.0E-32 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 MC49_RS05335 625affeffd7af87ea9026ec9bb272630 465 Gene3D G3DSA:1.10.8.60 296 367 2.8E-29 T 29-03-2018 MC49_RS05335 625affeffd7af87ea9026ec9bb272630 465 SUPERFAMILY SSF52540 130 341 2.72E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS05335 625affeffd7af87ea9026ec9bb272630 465 Pfam PF00308 Bacterial dnaA protein 131 347 1.2E-99 T 29-03-2018 IPR013317 Chromosomal replication initiator protein DnaA MC49_RS05335 625affeffd7af87ea9026ec9bb272630 465 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 6 463 1.3E-188 T 29-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 MC49_RS05335 625affeffd7af87ea9026ec9bb272630 465 SMART SM00760 373 442 6.1E-45 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 MC49_RS05335 625affeffd7af87ea9026ec9bb272630 465 SMART SM00382 162 364 2.2E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS05335 625affeffd7af87ea9026ec9bb272630 465 Pfam PF11638 DnaA N-terminal domain 4 64 5.3E-20 T 29-03-2018 IPR024633 DnaA N-terminal domain MC49_RS05335 625affeffd7af87ea9026ec9bb272630 465 Gene3D G3DSA:3.40.50.300 127 294 6.6E-22 T 29-03-2018 MC49_RS05335 625affeffd7af87ea9026ec9bb272630 465 ProSitePatterns PS01008 DnaA protein signature. 423 442 - T 29-03-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 MC49_RS05335 625affeffd7af87ea9026ec9bb272630 465 SUPERFAMILY SSF48295 361 464 3.4E-38 T 29-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 MC49_RS05335 625affeffd7af87ea9026ec9bb272630 465 Gene3D G3DSA:1.10.1750.10 368 464 1.5E-36 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 MC49_RS05335 625affeffd7af87ea9026ec9bb272630 465 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 423 442 1.2E-54 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MC49_RS05335 625affeffd7af87ea9026ec9bb272630 465 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 195 209 1.2E-54 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MC49_RS05335 625affeffd7af87ea9026ec9bb272630 465 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 227 241 1.2E-54 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MC49_RS05335 625affeffd7af87ea9026ec9bb272630 465 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 163 183 1.2E-54 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MC49_RS05335 625affeffd7af87ea9026ec9bb272630 465 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 261 288 1.2E-54 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like MC49_RS05335 625affeffd7af87ea9026ec9bb272630 465 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 3 464 34.686 T 29-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 MC49_RS14470 8523c0e03a855e9075b78351db1d3dc0 445 Gene3D G3DSA:3.40.640.10 106 309 1.0E-34 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS14470 8523c0e03a855e9075b78351db1d3dc0 445 Gene3D G3DSA:3.90.1150.10 310 441 1.2E-19 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS14470 8523c0e03a855e9075b78351db1d3dc0 445 SUPERFAMILY SSF46785 3 72 6.59E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS14470 8523c0e03a855e9075b78351db1d3dc0 445 SMART SM00345 9 68 9.2E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MC49_RS14470 8523c0e03a855e9075b78351db1d3dc0 445 Gene3D G3DSA:1.10.10.10 1 73 1.1E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS14470 8523c0e03a855e9075b78351db1d3dc0 445 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 68 1.6E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MC49_RS14470 8523c0e03a855e9075b78351db1d3dc0 445 SUPERFAMILY SSF53383 117 437 7.66E-69 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS14470 8523c0e03a855e9075b78351db1d3dc0 445 Pfam PF00155 Aminotransferase class I and II 116 428 9.7E-31 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MC49_RS14030 61a71e4a8ca2ef6cbbdc140a2ab5cc3d 254 TIGRFAM TIGR00740 TIGR00740: tRNA (cmo5U34)-methyltransferase 10 249 2.9E-120 T 29-03-2018 IPR005271 Carboxy-S-adenosyl-L-methionine synthase GO:0002098 MC49_RS14030 61a71e4a8ca2ef6cbbdc140a2ab5cc3d 254 Hamap MF_01589 Carboxy-S-adenosyl-L-methionine synthase [cmoA]. 9 249 40.663 T 29-03-2018 IPR005271 Carboxy-S-adenosyl-L-methionine synthase GO:0002098 MC49_RS14030 61a71e4a8ca2ef6cbbdc140a2ab5cc3d 254 Gene3D G3DSA:3.40.50.150 24 254 2.2E-38 T 29-03-2018 MC49_RS14030 61a71e4a8ca2ef6cbbdc140a2ab5cc3d 254 Pfam PF13649 Methyltransferase domain 66 165 1.1E-11 T 29-03-2018 MC49_RS14030 61a71e4a8ca2ef6cbbdc140a2ab5cc3d 254 PIRSF PIRSF006325 7 250 2.2E-119 T 29-03-2018 IPR005271 Carboxy-S-adenosyl-L-methionine synthase GO:0002098 MC49_RS14030 61a71e4a8ca2ef6cbbdc140a2ab5cc3d 254 SUPERFAMILY SSF53335 26 249 3.68E-38 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS03820 c28e360a3dacb9ebaaf7941a62cbedeb 420 Hamap MF_02029 UDP-N-acetyl-D-mannosamine dehydrogenase [wecC]. 1 420 78.274 T 29-03-2018 IPR032891 UDP-N-acetyl-D-mannosamine dehydrogenase WecC GO:0009246|GO:0089714 KEGG: 00520+1.1.1.336|MetaCyc: PWY-7335 MC49_RS03820 c28e360a3dacb9ebaaf7941a62cbedeb 420 Gene3D G3DSA:3.40.50.720 230 420 6.4E-47 T 29-03-2018 MC49_RS03820 c28e360a3dacb9ebaaf7941a62cbedeb 420 SUPERFAMILY SSF51735 5 198 2.39E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS03820 c28e360a3dacb9ebaaf7941a62cbedeb 420 PIRSF PIRSF000124 4 418 8.1E-71 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 MC49_RS03820 c28e360a3dacb9ebaaf7941a62cbedeb 420 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 206 293 1.4E-25 T 29-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MC49_RS03820 c28e360a3dacb9ebaaf7941a62cbedeb 420 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 5 416 4.8E-115 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 MC49_RS03820 c28e360a3dacb9ebaaf7941a62cbedeb 420 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 324 419 1.7E-17 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MC49_RS03820 c28e360a3dacb9ebaaf7941a62cbedeb 420 SUPERFAMILY SSF48179 206 298 3.57E-27 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MC49_RS03820 c28e360a3dacb9ebaaf7941a62cbedeb 420 Gene3D G3DSA:3.40.50.720 3 205 1.1E-43 T 29-03-2018 MC49_RS03820 c28e360a3dacb9ebaaf7941a62cbedeb 420 SMART SM00984 324 420 1.3E-22 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MC49_RS03820 c28e360a3dacb9ebaaf7941a62cbedeb 420 SUPERFAMILY SSF52413 311 419 3.4E-23 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MC49_RS03820 c28e360a3dacb9ebaaf7941a62cbedeb 420 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 5 189 2.0E-58 T 29-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MC49_RS03820 c28e360a3dacb9ebaaf7941a62cbedeb 420 Gene3D G3DSA:1.20.5.170 206 229 1.0E-14 T 29-03-2018 MC49_RS03820 c28e360a3dacb9ebaaf7941a62cbedeb 420 PIRSF PIRSF500136 1 420 1.5E-143 T 29-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 MC49_RS02840 963042307a0980ec3d71a47701332cd4 321 SUPERFAMILY SSF53850 97 313 1.59E-23 T 29-03-2018 MC49_RS02840 963042307a0980ec3d71a47701332cd4 321 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 66 9.4E-12 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS02840 963042307a0980ec3d71a47701332cd4 321 SUPERFAMILY SSF46785 6 85 9.19E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS02840 963042307a0980ec3d71a47701332cd4 321 Gene3D G3DSA:3.40.190.10 98 189 0.0036 T 29-03-2018 MC49_RS02840 963042307a0980ec3d71a47701332cd4 321 Pfam PF03466 LysR substrate binding domain 118 314 5.4E-15 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS02840 963042307a0980ec3d71a47701332cd4 321 Gene3D G3DSA:3.40.190.10 190 280 7.5E-10 T 29-03-2018 MC49_RS02840 963042307a0980ec3d71a47701332cd4 321 Gene3D G3DSA:1.10.10.10 1 91 1.1E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS11220 3eaad5293823e3b5148b92bb6835b833 396 Pfam PF00155 Aminotransferase class I and II 27 392 5.8E-90 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MC49_RS11220 3eaad5293823e3b5148b92bb6835b833 396 PRINTS PR00799 Aspartate aminotransferase signature 273 298 1.5E-39 T 29-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 MC49_RS11220 3eaad5293823e3b5148b92bb6835b833 396 PRINTS PR00799 Aspartate aminotransferase signature 175 194 1.5E-39 T 29-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 MC49_RS11220 3eaad5293823e3b5148b92bb6835b833 396 PRINTS PR00799 Aspartate aminotransferase signature 206 218 1.5E-39 T 29-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 MC49_RS11220 3eaad5293823e3b5148b92bb6835b833 396 PRINTS PR00799 Aspartate aminotransferase signature 341 359 1.5E-39 T 29-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 MC49_RS11220 3eaad5293823e3b5148b92bb6835b833 396 SUPERFAMILY SSF53383 1 395 1.24E-119 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS11220 3eaad5293823e3b5148b92bb6835b833 396 Gene3D G3DSA:3.90.1150.10 1 157 1.2E-25 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS11220 3eaad5293823e3b5148b92bb6835b833 396 Gene3D G3DSA:3.90.1150.10 241 396 4.5E-51 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS11220 3eaad5293823e3b5148b92bb6835b833 396 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 243 256 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 MC49_RS16360 344d50011a024426bfefa287df392968 201 Hamap MF_00837 Lipid A palmitoyltransferase PagP [pagP]. 4 201 42.655 T 29-03-2018 IPR009746 Antimicrobial peptide resistance/lipid A acylation PagP KEGG: 00565+2.3.1.25 MC49_RS16360 344d50011a024426bfefa287df392968 201 Gene3D G3DSA:2.40.160.20 45 201 3.2E-63 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MC49_RS16360 344d50011a024426bfefa287df392968 201 ProDom PD103779 CRCA ANTIMICROBIAL RESISTANCE LIPOPROTEIN RCP A PEPTIDE ACYLATION LIPID EXPORTED 50 189 6.0E-55 T 29-03-2018 IPR009746 Antimicrobial peptide resistance/lipid A acylation PagP KEGG: 00565+2.3.1.25 MC49_RS16360 344d50011a024426bfefa287df392968 201 SUPERFAMILY SSF56925 44 201 5.18E-77 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MC49_RS16360 344d50011a024426bfefa287df392968 201 Pfam PF07017 Antimicrobial peptide resistance and lipid A acylation protein PagP 53 198 7.0E-72 T 29-03-2018 IPR009746 Antimicrobial peptide resistance/lipid A acylation PagP KEGG: 00565+2.3.1.25 MC49_RS03915 b3cbc8620ffcf27324479a3952548b51 510 SUPERFAMILY SSF54211 11 168 1.06E-29 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MC49_RS03915 b3cbc8620ffcf27324479a3952548b51 510 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 6 496 4.5E-194 T 29-03-2018 IPR004482 Mg chelatase-related protein MC49_RS03915 b3cbc8620ffcf27324479a3952548b51 510 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 341 353 5.4E-7 T 29-03-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 MC49_RS03915 b3cbc8620ffcf27324479a3952548b51 510 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 209 224 5.4E-7 T 29-03-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 MC49_RS03915 b3cbc8620ffcf27324479a3952548b51 510 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 289 303 5.4E-7 T 29-03-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 MC49_RS03915 b3cbc8620ffcf27324479a3952548b51 510 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 317 330 5.4E-7 T 29-03-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 MC49_RS03915 b3cbc8620ffcf27324479a3952548b51 510 Pfam PF01078 Magnesium chelatase, subunit ChlI 191 390 9.2E-87 T 29-03-2018 IPR000523 Magnesium chelatase ChlI domain MC49_RS03915 b3cbc8620ffcf27324479a3952548b51 510 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 405 496 2.1E-24 T 29-03-2018 IPR025158 Mg chelatase-related protein, C-terminal domain MC49_RS03915 b3cbc8620ffcf27324479a3952548b51 510 SMART SM00382 210 392 1.6E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS03915 b3cbc8620ffcf27324479a3952548b51 510 Gene3D G3DSA:3.40.50.300 180 429 1.2E-23 T 29-03-2018 MC49_RS03915 b3cbc8620ffcf27324479a3952548b51 510 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 140 9.5E-46 T 29-03-2018 MC49_RS03915 b3cbc8620ffcf27324479a3952548b51 510 Gene3D G3DSA:3.30.230.10 1 179 3.3E-38 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MC49_RS03915 b3cbc8620ffcf27324479a3952548b51 510 SUPERFAMILY SSF52540 190 503 4.6E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS04830 ec65ab7e44e9ad39769b8130aec5f88a 993 SMART SM00869 700 978 5.7E-24 T 29-03-2018 IPR005546 Autotransporter beta-domain MC49_RS04830 ec65ab7e44e9ad39769b8130aec5f88a 993 Pfam PF03797 Autotransporter beta-domain 703 967 1.2E-37 T 29-03-2018 IPR005546 Autotransporter beta-domain MC49_RS04830 ec65ab7e44e9ad39769b8130aec5f88a 993 SUPERFAMILY SSF103515 668 993 5.62E-39 T 29-03-2018 IPR005546 Autotransporter beta-domain MC49_RS04830 ec65ab7e44e9ad39769b8130aec5f88a 993 Gene3D G3DSA:2.40.128.130 650 993 2.1E-43 T 29-03-2018 MC49_RS04830 ec65ab7e44e9ad39769b8130aec5f88a 993 SUPERFAMILY SSF51126 108 621 1.38E-7 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor MC49_RS04830 ec65ab7e44e9ad39769b8130aec5f88a 993 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 526 993 8.7E-49 T 29-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 MC49_RS18645 3f5b53e0ab8b66308700ec985633e507 488 Pfam PF02875 Mur ligase family, glutamate ligase domain 341 415 2.1E-20 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MC49_RS18645 3f5b53e0ab8b66308700ec985633e507 488 Pfam PF01225 Mur ligase family, catalytic domain 21 118 2.5E-29 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MC49_RS18645 3f5b53e0ab8b66308700ec985633e507 488 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 19 481 42.939 T 29-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MC49_RS18645 3f5b53e0ab8b66308700ec985633e507 488 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 21 475 1.8E-177 T 29-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MC49_RS18645 3f5b53e0ab8b66308700ec985633e507 488 SUPERFAMILY SSF53244 323 476 1.26E-45 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MC49_RS18645 3f5b53e0ab8b66308700ec985633e507 488 SUPERFAMILY SSF51984 20 106 4.97E-29 T 29-03-2018 MC49_RS18645 3f5b53e0ab8b66308700ec985633e507 488 Gene3D G3DSA:3.40.1190.10 108 324 2.0E-52 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MC49_RS18645 3f5b53e0ab8b66308700ec985633e507 488 SUPERFAMILY SSF53623 105 322 2.88E-72 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MC49_RS18645 3f5b53e0ab8b66308700ec985633e507 488 Pfam PF08245 Mur ligase middle domain 124 304 1.5E-28 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MC49_RS18645 3f5b53e0ab8b66308700ec985633e507 488 Gene3D G3DSA:3.40.50.720 1 107 1.8E-19 T 29-03-2018 MC49_RS18645 3f5b53e0ab8b66308700ec985633e507 488 Gene3D G3DSA:3.90.190.20 325 480 2.0E-33 T 29-03-2018 MC49_RS16090 1e129c86a253d7c8b8fc7a38ceba3249 542 SUPERFAMILY SSF52518 4 173 4.15E-39 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MC49_RS16090 1e129c86a253d7c8b8fc7a38ceba3249 542 SUPERFAMILY SSF52467 183 330 1.85E-47 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MC49_RS16090 1e129c86a253d7c8b8fc7a38ceba3249 542 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 191 324 6.4E-18 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MC49_RS16090 1e129c86a253d7c8b8fc7a38ceba3249 542 Gene3D G3DSA:3.40.50.970 3 185 2.7E-35 T 29-03-2018 MC49_RS16090 1e129c86a253d7c8b8fc7a38ceba3249 542 SUPERFAMILY SSF52518 356 541 2.95E-42 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MC49_RS16090 1e129c86a253d7c8b8fc7a38ceba3249 542 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 390 532 4.0E-25 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MC49_RS16090 1e129c86a253d7c8b8fc7a38ceba3249 542 Gene3D G3DSA:3.40.50.970 339 537 3.0E-39 T 29-03-2018 MC49_RS16090 1e129c86a253d7c8b8fc7a38ceba3249 542 Gene3D G3DSA:3.40.50.1220 186 338 2.3E-25 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MC49_RS16090 1e129c86a253d7c8b8fc7a38ceba3249 542 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 171 1.8E-40 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MC49_RS16075 8f8bf98e9d7b5ad5820079ebe4aff675 376 Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. 3 376 51.919 T 29-03-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 MC49_RS16075 8f8bf98e9d7b5ad5820079ebe4aff675 376 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 62 71 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 MC49_RS16075 8f8bf98e9d7b5ad5820079ebe4aff675 376 TIGRFAM TIGR01246 dapE_proteo: succinyl-diaminopimelate desuccinylase 5 374 3.3E-170 T 29-03-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 MC49_RS16075 8f8bf98e9d7b5ad5820079ebe4aff675 376 Gene3D G3DSA:3.40.630.10 304 376 9.8E-4 T 29-03-2018 MC49_RS16075 8f8bf98e9d7b5ad5820079ebe4aff675 376 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 98 137 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 MC49_RS16075 8f8bf98e9d7b5ad5820079ebe4aff675 376 Pfam PF07687 Peptidase dimerisation domain 176 283 2.3E-26 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain MC49_RS16075 8f8bf98e9d7b5ad5820079ebe4aff675 376 Gene3D G3DSA:3.40.630.10 2 281 5.1E-62 T 29-03-2018 MC49_RS16075 8f8bf98e9d7b5ad5820079ebe4aff675 376 SUPERFAMILY SSF55031 180 289 2.39E-29 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain MC49_RS16075 8f8bf98e9d7b5ad5820079ebe4aff675 376 SUPERFAMILY SSF53187 6 179 7.38E-65 T 29-03-2018 MC49_RS16075 8f8bf98e9d7b5ad5820079ebe4aff675 376 SUPERFAMILY SSF53187 293 374 7.38E-65 T 29-03-2018 MC49_RS16075 8f8bf98e9d7b5ad5820079ebe4aff675 376 Pfam PF01546 Peptidase family M20/M25/M40 63 372 3.2E-41 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 MC49_RS12220 5e4e6db62c137d8da153dd2feb09821e 301 Gene3D G3DSA:3.40.1500.10 2 301 4.9E-134 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MC49_RS12220 5e4e6db62c137d8da153dd2feb09821e 301 ProSitePatterns PS01021 Coproporphyrinogen III oxidase signature. 166 190 - T 29-03-2018 IPR018375 Coproporphyrinogen III oxidase, conserved site GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MC49_RS12220 5e4e6db62c137d8da153dd2feb09821e 301 SUPERFAMILY SSF102886 8 301 3.66E-134 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MC49_RS12220 5e4e6db62c137d8da153dd2feb09821e 301 PIRSF PIRSF000166 3 301 3.2E-123 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MC49_RS12220 5e4e6db62c137d8da153dd2feb09821e 301 Pfam PF01218 Coproporphyrinogen III oxidase 9 301 6.5E-129 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MC49_RS12220 5e4e6db62c137d8da153dd2feb09821e 301 PRINTS PR00073 Coprogen oxidase signature 31 47 6.9E-87 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MC49_RS12220 5e4e6db62c137d8da153dd2feb09821e 301 PRINTS PR00073 Coprogen oxidase signature 90 114 6.9E-87 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MC49_RS12220 5e4e6db62c137d8da153dd2feb09821e 301 PRINTS PR00073 Coprogen oxidase signature 162 191 6.9E-87 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MC49_RS12220 5e4e6db62c137d8da153dd2feb09821e 301 PRINTS PR00073 Coprogen oxidase signature 125 147 6.9E-87 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MC49_RS12220 5e4e6db62c137d8da153dd2feb09821e 301 PRINTS PR00073 Coprogen oxidase signature 262 288 6.9E-87 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MC49_RS12220 5e4e6db62c137d8da153dd2feb09821e 301 PRINTS PR00073 Coprogen oxidase signature 48 69 6.9E-87 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MC49_RS12220 5e4e6db62c137d8da153dd2feb09821e 301 PRINTS PR00073 Coprogen oxidase signature 234 261 6.9E-87 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MC49_RS12220 5e4e6db62c137d8da153dd2feb09821e 301 Hamap MF_00333 Oxygen-dependent coproporphyrinogen-III oxidase [hemF]. 3 277 56.214 T 29-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MC49_RS13755 33e398b6b3a3123d1a8b88aeaa118d5f 97 Pfam PF17274 Family of unknown function (DUF5339) 23 94 4.2E-23 T 29-03-2018 IPR020493 Uncharacterised protein family HI0310 MC49_RS00380 2ea44544b658d3fb661680dcc0b7a235 265 SUPERFAMILY SSF53335 5 256 2.6E-29 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS00380 2ea44544b658d3fb661680dcc0b7a235 265 Pfam PF00145 C-5 cytosine-specific DNA methylase 76 167 3.2E-13 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS00380 2ea44544b658d3fb661680dcc0b7a235 265 Gene3D G3DSA:3.40.50.150 2 173 2.0E-22 T 29-03-2018 MC49_RS06040 53d34148cb926be219efcf29ab07b445 461 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 374 394 - T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 MC49_RS06040 53d34148cb926be219efcf29ab07b445 461 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 28 456 3.7E-135 T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 MC49_RS06040 53d34148cb926be219efcf29ab07b445 461 Pfam PF00860 Permease family 33 425 1.2E-104 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 MC49_RS02695 568518d269f6b65884f401601988d067 495 SUPERFAMILY SSF140693 432 485 5.89E-6 T 29-03-2018 IPR009483 Invasion plasmid antigen IpaD GO:0009405 MC49_RS02695 568518d269f6b65884f401601988d067 495 Gene3D G3DSA:1.20.1710.10 106 495 9.7E-64 T 29-03-2018 MC49_RS01405 29d61b6250a4837ac2b2942fcbd8e444 120 Hamap MF_00048 UPF0102 protein YraN [yraN]. 3 115 22.316 T 29-03-2018 IPR003509 Uncharacterised protein family UPF0102 MC49_RS01405 29d61b6250a4837ac2b2942fcbd8e444 120 Gene3D G3DSA:3.40.1350.10 9 120 1.7E-34 T 29-03-2018 MC49_RS01405 29d61b6250a4837ac2b2942fcbd8e444 120 SUPERFAMILY SSF52980 6 112 1.74E-20 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MC49_RS01405 29d61b6250a4837ac2b2942fcbd8e444 120 Pfam PF02021 Uncharacterised protein family UPF0102 11 102 5.3E-26 T 29-03-2018 IPR003509 Uncharacterised protein family UPF0102 MC49_RS01405 29d61b6250a4837ac2b2942fcbd8e444 120 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 6 115 1.3E-39 T 29-03-2018 IPR003509 Uncharacterised protein family UPF0102 MC49_RS00960 48654562546b04a829431e5597759f51 81 Gene3D G3DSA:3.30.110.40 9 81 4.9E-22 T 29-03-2018 IPR001455 TusA-like domain MC49_RS00960 48654562546b04a829431e5597759f51 81 SUPERFAMILY SSF64307 6 81 1.29E-24 T 29-03-2018 IPR001455 TusA-like domain MC49_RS00960 48654562546b04a829431e5597759f51 81 Pfam PF01206 Sulfurtransferase TusA 13 81 7.6E-20 T 29-03-2018 IPR001455 TusA-like domain MC49_RS00960 48654562546b04a829431e5597759f51 81 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 14 38 - T 29-03-2018 IPR001455 TusA-like domain MC49_RS09620 db5de2f82670ebf2e02f7c370e4360af 340 Gene3D G3DSA:3.30.450.90 1 100 1.4E-15 T 29-03-2018 MC49_RS09620 db5de2f82670ebf2e02f7c370e4360af 340 Gene3D G3DSA:3.40.50.300 271 335 1.1E-4 T 29-03-2018 MC49_RS09620 db5de2f82670ebf2e02f7c370e4360af 340 Gene3D G3DSA:3.40.50.300 119 270 1.5E-22 T 29-03-2018 MC49_RS09620 db5de2f82670ebf2e02f7c370e4360af 340 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 3 334 9.8E-113 T 29-03-2018 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 MC49_RS09620 db5de2f82670ebf2e02f7c370e4360af 340 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 194 208 - T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 MC49_RS09620 db5de2f82670ebf2e02f7c370e4360af 340 SUPERFAMILY SSF52540 3 329 6.36E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS09620 db5de2f82670ebf2e02f7c370e4360af 340 Pfam PF00437 Type II/IV secretion system protein 115 263 3.4E-40 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 MC49_RS15185 f2222a00fcfc9187fb5dae017d948959 211 SUPERFAMILY SSF56925 23 211 8.89E-32 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MC49_RS15185 f2222a00fcfc9187fb5dae017d948959 211 Gene3D G3DSA:2.40.160.20 22 211 8.6E-39 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MC49_RS15185 f2222a00fcfc9187fb5dae017d948959 211 ProSitePatterns PS00695 Enterobacterial virulence outer membrane protein signature 2. 203 211 - T 29-03-2018 IPR000758 Virulence-related outer membrane protein GO:0009279 MC49_RS15185 f2222a00fcfc9187fb5dae017d948959 211 Pfam PF03922 OmpW family 23 211 3.2E-62 T 29-03-2018 IPR005618 Outer membrane protein, OmpW GO:0019867 MC49_RS18920 43e3a088187bc7e3eedd6abf14b16fe5 287 SUPERFAMILY SSF53335 89 286 3.84E-29 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS18920 43e3a088187bc7e3eedd6abf14b16fe5 287 Gene3D G3DSA:3.40.50.150 87 241 1.2E-16 T 29-03-2018 MC49_RS18920 43e3a088187bc7e3eedd6abf14b16fe5 287 Pfam PF03848 Tellurite resistance protein TehB 89 282 3.9E-69 T 29-03-2018 IPR015985 Tellurite resistance methyltransferase TehB-like domain MC49_RS18920 43e3a088187bc7e3eedd6abf14b16fe5 287 SUPERFAMILY SSF51197 1 99 2.61E-32 T 29-03-2018 MC49_RS18920 43e3a088187bc7e3eedd6abf14b16fe5 287 Pfam PF09313 Domain of unknown function (DUF1971) 8 87 3.7E-27 T 29-03-2018 IPR015392 Domain of unknown function DUF1971 MC49_RS18920 43e3a088187bc7e3eedd6abf14b16fe5 287 PIRSF PIRSF005215 1 287 3.8E-108 T 29-03-2018 IPR014431 Tellurite resistance methyltransferase, TehB type-2 MC49_RS18920 43e3a088187bc7e3eedd6abf14b16fe5 287 Gene3D G3DSA:2.60.120.10 1 86 4.4E-34 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MC49_RS18920 43e3a088187bc7e3eedd6abf14b16fe5 287 TIGRFAM TIGR00477 tehB: tellurite resistance protein TehB 63 285 3.7E-82 T 29-03-2018 IPR004537 Tellurite resistance methyltransferase, TehB GO:0005737|GO:0008757|GO:0046690 MC49_RS05730 875489a5619f5f88c094b926ef359401 354 SUPERFAMILY SSF54631 12 56 8.83E-7 T 29-03-2018 MC49_RS05730 875489a5619f5f88c094b926ef359401 354 SUPERFAMILY SSF53448 49 347 3.05E-66 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MC49_RS05730 875489a5619f5f88c094b926ef359401 354 Gene3D G3DSA:3.10.580.10 1 114 2.9E-14 T 29-03-2018 MC49_RS05730 875489a5619f5f88c094b926ef359401 354 Pfam PF00483 Nucleotidyl transferase 125 347 1.9E-34 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MC49_RS05730 875489a5619f5f88c094b926ef359401 354 Pfam PF00571 CBS domain 12 54 2.4E-6 T 29-03-2018 IPR000644 CBS domain MC49_RS05730 875489a5619f5f88c094b926ef359401 354 Gene3D G3DSA:3.90.550.10 115 349 6.7E-51 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MC49_RS05730 875489a5619f5f88c094b926ef359401 354 SMART SM00116 70 117 37.0 T 29-03-2018 IPR000644 CBS domain MC49_RS05730 875489a5619f5f88c094b926ef359401 354 SMART SM00116 6 54 0.058 T 29-03-2018 IPR000644 CBS domain MC49_RS16515 0034d786309e9c33474c072794cebfbc 450 SUPERFAMILY SSF140490 337 429 7.85E-32 T 29-03-2018 MC49_RS16515 0034d786309e9c33474c072794cebfbc 450 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 176 191 - T 29-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16515 0034d786309e9c33474c072794cebfbc 450 SMART SM00928 340 385 2.1E-22 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16515 0034d786309e9c33474c072794cebfbc 450 SUPERFAMILY SSF142984 252 334 4.32E-21 T 29-03-2018 MC49_RS16515 0034d786309e9c33474c072794cebfbc 450 SUPERFAMILY SSF142019 15 241 1.96E-85 T 29-03-2018 MC49_RS16515 0034d786309e9c33474c072794cebfbc 450 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 15 427 4.2E-200 T 29-03-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16515 0034d786309e9c33474c072794cebfbc 450 Pfam PF10531 SLBB domain 257 289 1.6E-6 T 29-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16515 0034d786309e9c33474c072794cebfbc 450 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 56 228 6.5E-51 T 29-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16515 0034d786309e9c33474c072794cebfbc 450 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 353 364 - T 29-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16515 0034d786309e9c33474c072794cebfbc 450 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 343 425 6.7E-27 T 29-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS07705 c0b1553915b74b46916e27dc3731e120 217 Gene3D G3DSA:3.90.870.10 3 216 3.2E-90 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain MC49_RS07705 c0b1553915b74b46916e27dc3731e120 217 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 11 213 42.571 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MC49_RS07705 c0b1553915b74b46916e27dc3731e120 217 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 13 209 3.1E-82 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MC49_RS07705 c0b1553915b74b46916e27dc3731e120 217 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 17 208 5.9E-83 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MC49_RS07705 c0b1553915b74b46916e27dc3731e120 217 SUPERFAMILY SSF55821 7 211 2.98E-86 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain MC49_RS09940 3ee9801957ac1a5cb5d5907e988577ae 857 SMART SM01086 766 855 3.9E-37 T 29-03-2018 IPR019489 Clp ATPase, C-terminal MC49_RS09940 3ee9801957ac1a5cb5d5907e988577ae 857 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 7.1E-12 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 MC49_RS09940 3ee9801957ac1a5cb5d5907e988577ae 857 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 94 145 3.0E-11 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 MC49_RS09940 3ee9801957ac1a5cb5d5907e988577ae 857 Gene3D G3DSA:1.10.8.60 766 856 2.3E-24 T 29-03-2018 MC49_RS09940 3ee9801957ac1a5cb5d5907e988577ae 857 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 646 664 1.3E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 MC49_RS09940 3ee9801957ac1a5cb5d5907e988577ae 857 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 708 722 1.3E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 MC49_RS09940 3ee9801957ac1a5cb5d5907e988577ae 857 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 601 619 1.3E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 MC49_RS09940 3ee9801957ac1a5cb5d5907e988577ae 857 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 675 693 1.3E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 MC49_RS09940 3ee9801957ac1a5cb5d5907e988577ae 857 SUPERFAMILY SSF52540 159 545 1.23E-101 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS09940 3ee9801957ac1a5cb5d5907e988577ae 857 Gene3D G3DSA:3.40.50.300 157 342 1.6E-25 T 29-03-2018 MC49_RS09940 3ee9801957ac1a5cb5d5907e988577ae 857 SUPERFAMILY SSF52540 546 851 1.84E-86 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS09940 3ee9801957ac1a5cb5d5907e988577ae 857 SMART SM00382 597 755 3.9E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS09940 3ee9801957ac1a5cb5d5907e988577ae 857 SMART SM00382 198 344 5.4E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS09940 3ee9801957ac1a5cb5d5907e988577ae 857 Gene3D G3DSA:1.10.1780.10 1 151 8.2E-35 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 MC49_RS09940 3ee9801957ac1a5cb5d5907e988577ae 857 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 854 0.0 T 29-03-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 MC49_RS09940 3ee9801957ac1a5cb5d5907e988577ae 857 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 294 306 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 MC49_RS09940 3ee9801957ac1a5cb5d5907e988577ae 857 Pfam PF07724 AAA domain (Cdc48 subfamily) 596 760 6.4E-57 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MC49_RS09940 3ee9801957ac1a5cb5d5907e988577ae 857 Gene3D G3DSA:3.40.50.300 552 765 3.8E-54 T 29-03-2018 MC49_RS09940 3ee9801957ac1a5cb5d5907e988577ae 857 Gene3D G3DSA:1.10.8.60 343 547 8.3E-45 T 29-03-2018 MC49_RS09940 3ee9801957ac1a5cb5d5907e988577ae 857 SUPERFAMILY SSF81923 4 156 2.75E-41 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 MC49_RS09940 3ee9801957ac1a5cb5d5907e988577ae 857 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 766 845 9.9E-28 T 29-03-2018 IPR019489 Clp ATPase, C-terminal MC49_RS09940 3ee9801957ac1a5cb5d5907e988577ae 857 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 203 335 5.2E-13 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MC49_RS09940 3ee9801957ac1a5cb5d5907e988577ae 857 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 631 649 - T 29-03-2018 IPR028299 ClpA/B, conserved site 2 MC49_RS12450 652c99ed80139e14801a6e10bfd56f5a 524 Pfam PF02203 Tar ligand binding domain homologue 4 169 5.0E-22 T 29-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 MC49_RS12450 652c99ed80139e14801a6e10bfd56f5a 524 SMART SM00304 211 263 1.7E-6 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MC49_RS12450 652c99ed80139e14801a6e10bfd56f5a 524 SMART SM00283 264 511 1.7E-92 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MC49_RS12450 652c99ed80139e14801a6e10bfd56f5a 524 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 322 479 4.5E-55 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MC49_RS12450 652c99ed80139e14801a6e10bfd56f5a 524 SUPERFAMILY SSF58104 232 512 4.84E-74 T 29-03-2018 MC49_RS12450 652c99ed80139e14801a6e10bfd56f5a 524 SUPERFAMILY SSF47170 26 176 1.83E-23 T 29-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 MC49_RS12450 652c99ed80139e14801a6e10bfd56f5a 524 SMART SM00319 45 177 1.5E-5 T 29-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 MC49_RS12450 652c99ed80139e14801a6e10bfd56f5a 524 Gene3D G3DSA:1.20.120.30 24 168 6.3E-18 T 29-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain MC49_RS12450 652c99ed80139e14801a6e10bfd56f5a 524 Gene3D G3DSA:1.10.287.950 320 515 5.1E-47 T 29-03-2018 MC49_RS12450 652c99ed80139e14801a6e10bfd56f5a 524 Gene3D G3DSA:1.10.287.950 169 319 1.4E-18 T 29-03-2018 MC49_RS12450 652c99ed80139e14801a6e10bfd56f5a 524 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 61 76 9.0E-71 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS12450 652c99ed80139e14801a6e10bfd56f5a 524 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 285 314 9.0E-71 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS12450 652c99ed80139e14801a6e10bfd56f5a 524 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 6 31 9.0E-71 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS12450 652c99ed80139e14801a6e10bfd56f5a 524 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 391 420 9.0E-71 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS12450 652c99ed80139e14801a6e10bfd56f5a 524 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 362 389 9.0E-71 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS12450 652c99ed80139e14801a6e10bfd56f5a 524 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 439 468 9.0E-71 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS18490 a2b4f66c55bbef682d5fc73c982b0cea 218 SUPERFAMILY SSF75445 127 198 3.92E-24 T 29-03-2018 MC49_RS18490 a2b4f66c55bbef682d5fc73c982b0cea 218 Gene3D G3DSA:3.40.50.1360 1 137 6.6E-43 T 29-03-2018 MC49_RS18490 a2b4f66c55bbef682d5fc73c982b0cea 218 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 49 213 5.0E-62 T 29-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MC49_RS18490 a2b4f66c55bbef682d5fc73c982b0cea 218 Gene3D G3DSA:3.30.70.260 138 196 2.3E-23 T 29-03-2018 MC49_RS18490 a2b4f66c55bbef682d5fc73c982b0cea 218 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 3 217 35.074 T 29-03-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MC49_RS18490 a2b4f66c55bbef682d5fc73c982b0cea 218 SUPERFAMILY SSF100950 2 146 1.26E-48 T 29-03-2018 MC49_RS18490 a2b4f66c55bbef682d5fc73c982b0cea 218 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 6 215 4.1E-71 T 29-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MC49_RS07940 ebcd3ea8c8896562082873a8f8f43aee 148 SUPERFAMILY SSF82649 3 144 3.35E-41 T 29-03-2018 MC49_RS07940 ebcd3ea8c8896562082873a8f8f43aee 148 TIGRFAM TIGR03391 FeS_syn_CsdE: cysteine desulfurase, sulfur acceptor subunit CsdE 7 143 1.1E-56 T 29-03-2018 IPR017763 Cysteine desulfurase, sulphur acceptor subunit CsdE MC49_RS07940 ebcd3ea8c8896562082873a8f8f43aee 148 Gene3D G3DSA:3.90.1010.10 1 146 2.3E-41 T 29-03-2018 MC49_RS07940 ebcd3ea8c8896562082873a8f8f43aee 148 Pfam PF02657 Fe-S metabolism associated domain 21 138 2.6E-37 T 29-03-2018 IPR003808 Fe-S metabolism associated domain, SufE-like MC49_RS16770 06731855c842af8c7dd276d46396560b 321 SUPERFAMILY SSF46785 24 99 3.91E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS16770 06731855c842af8c7dd276d46396560b 321 Pfam PF03466 LysR substrate binding domain 107 315 1.8E-25 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS16770 06731855c842af8c7dd276d46396560b 321 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 25 84 1.9E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS16770 06731855c842af8c7dd276d46396560b 321 Gene3D G3DSA:1.10.10.10 9 108 4.0E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS16770 06731855c842af8c7dd276d46396560b 321 TIGRFAM TIGR02036 dsdC: D-serine deaminase transcriptional activator 16 316 5.8E-145 T 29-03-2018 IPR011781 D-serine deaminase transcriptional activator MC49_RS16770 06731855c842af8c7dd276d46396560b 321 Gene3D G3DSA:3.40.190.10 193 286 1.3E-15 T 29-03-2018 MC49_RS16770 06731855c842af8c7dd276d46396560b 321 SUPERFAMILY SSF53850 107 318 1.65E-27 T 29-03-2018 MC49_RS16770 06731855c842af8c7dd276d46396560b 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 8.6E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS16770 06731855c842af8c7dd276d46396560b 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 61 72 8.6E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS16770 06731855c842af8c7dd276d46396560b 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 51 61 8.6E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS16770 06731855c842af8c7dd276d46396560b 321 Gene3D G3DSA:3.40.190.10 109 192 8.8E-13 T 29-03-2018 MC49_RS08065 6539f0ac734f8f57aae6496497d4e8f6 451 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 2 450 5.0E-146 T 29-03-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 MC49_RS08065 6539f0ac734f8f57aae6496497d4e8f6 451 Gene3D G3DSA:2.30.42.10 126 220 1.5E-8 T 29-03-2018 MC49_RS08065 6539f0ac734f8f57aae6496497d4e8f6 451 SMART SM00228 115 186 0.18 T 29-03-2018 IPR001478 PDZ domain GO:0005515 MC49_RS08065 6539f0ac734f8f57aae6496497d4e8f6 451 SMART SM00228 211 280 3.0E-9 T 29-03-2018 IPR001478 PDZ domain GO:0005515 MC49_RS08065 6539f0ac734f8f57aae6496497d4e8f6 451 SUPERFAMILY SSF50156 86 185 3.29E-12 T 29-03-2018 IPR001478 PDZ domain GO:0005515 MC49_RS08065 6539f0ac734f8f57aae6496497d4e8f6 451 Pfam PF13180 PDZ domain 226 286 2.3E-7 T 29-03-2018 IPR001478 PDZ domain GO:0005515 MC49_RS08065 6539f0ac734f8f57aae6496497d4e8f6 451 SUPERFAMILY SSF50156 195 290 2.76E-16 T 29-03-2018 IPR001478 PDZ domain GO:0005515 MC49_RS08065 6539f0ac734f8f57aae6496497d4e8f6 451 Pfam PF02163 Peptidase family M50 10 439 1.1E-84 T 29-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 MC49_RS08065 6539f0ac734f8f57aae6496497d4e8f6 451 Gene3D G3DSA:2.30.42.10 224 309 2.5E-18 T 29-03-2018 MC49_RS17360 38c1d422a8acfa334cebc211160c3cc8 284 Pfam PF03824 High-affinity nickel-transport protein 13 281 3.6E-55 T 29-03-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 MC49_RS17360 38c1d422a8acfa334cebc211160c3cc8 284 Gene3D G3DSA:3.40.50.1980 83 174 1.1E-4 T 29-03-2018 MC49_RS12870 e4bfcde6537b0529b3dc8c5dd20fa1e6 131 Gene3D G3DSA:2.40.50.140 1 120 8.3E-30 T 29-03-2018 MC49_RS12870 e4bfcde6537b0529b3dc8c5dd20fa1e6 131 SUPERFAMILY SSF50249 3 131 9.25E-33 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS12870 e4bfcde6537b0529b3dc8c5dd20fa1e6 131 Hamap MF_00984 Single-stranded DNA-binding protein. 3 105 23.687 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 MC49_RS12870 e4bfcde6537b0529b3dc8c5dd20fa1e6 131 PIRSF PIRSF002070 1 129 2.7E-25 T 29-03-2018 MC49_RS12870 e4bfcde6537b0529b3dc8c5dd20fa1e6 131 Pfam PF00436 Single-strand binding protein family 3 100 1.6E-21 T 29-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 MC49_RS12870 e4bfcde6537b0529b3dc8c5dd20fa1e6 131 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 114 3.2E-23 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 MC49_RS02970 55c3862838fa36efb4b76fae5e377f2d 494 Gene3D G3DSA:3.40.605.10 3 275 1.7E-100 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MC49_RS02970 55c3862838fa36efb4b76fae5e377f2d 494 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 259 266 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 MC49_RS02970 55c3862838fa36efb4b76fae5e377f2d 494 Pfam PF00171 Aldehyde dehydrogenase family 25 487 1.2E-176 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MC49_RS02970 55c3862838fa36efb4b76fae5e377f2d 494 Gene3D G3DSA:3.40.309.10 276 473 4.3E-77 T 29-03-2018 MC49_RS02970 55c3862838fa36efb4b76fae5e377f2d 494 SUPERFAMILY SSF53720 14 490 2.09E-173 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MC49_RS02230 03bc0a29af6854cda7884746353597e9 503 Pfam PF07916 TraG-like protein, N-terminal region 11 477 6.2E-66 T 29-03-2018 IPR012931 TraG-like, N-terminal MC49_RS18430 d18dc1f1679af7ddc61816a8255a2c2b 201 SUPERFAMILY SSF109604 14 192 9.74E-43 T 29-03-2018 MC49_RS18430 d18dc1f1679af7ddc61816a8255a2c2b 201 Gene3D G3DSA:1.10.3210.10 6 201 3.7E-42 T 29-03-2018 MC49_RS18430 d18dc1f1679af7ddc61816a8255a2c2b 201 Pfam PF13023 HD domain 24 183 3.0E-49 T 29-03-2018 IPR006674 HD domain MC49_RS15885 d11e172677db08c8d1d4caebd6d9dab7 122 SUPERFAMILY SSF46689 5 56 1.34E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS15885 d11e172677db08c8d1d4caebd6d9dab7 122 SMART SM00342 22 105 5.1E-35 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MC49_RS15885 d11e172677db08c8d1d4caebd6d9dab7 122 Gene3D G3DSA:1.10.10.60 1 58 4.4E-13 T 29-03-2018 MC49_RS15885 d11e172677db08c8d1d4caebd6d9dab7 122 Gene3D G3DSA:1.10.10.60 59 115 2.6E-15 T 29-03-2018 MC49_RS15885 d11e172677db08c8d1d4caebd6d9dab7 122 Pfam PF12833 Helix-turn-helix domain 28 106 1.0E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MC49_RS15885 d11e172677db08c8d1d4caebd6d9dab7 122 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 59 101 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MC49_RS15885 d11e172677db08c8d1d4caebd6d9dab7 122 SUPERFAMILY SSF46689 58 108 2.99E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS15885 d11e172677db08c8d1d4caebd6d9dab7 122 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 74 89 2.0E-8 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MC49_RS15885 d11e172677db08c8d1d4caebd6d9dab7 122 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 89 105 2.0E-8 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MC49_RS03045 dc4da3aed1381513632ee5d598a129a1 287 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 285 5.4E-97 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MC49_RS03045 dc4da3aed1381513632ee5d598a129a1 287 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 2 285 6.5E-109 T 29-03-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 MC49_RS03045 dc4da3aed1381513632ee5d598a129a1 287 PIRSF PIRSF001359 1 286 2.7E-106 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MC49_RS03045 dc4da3aed1381513632ee5d598a129a1 287 SUPERFAMILY SSF51569 4 285 9.96E-92 T 29-03-2018 MC49_RS03045 dc4da3aed1381513632ee5d598a129a1 287 Gene3D G3DSA:3.20.20.70 1 287 9.0E-92 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS03045 dc4da3aed1381513632ee5d598a129a1 287 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 285 1.3E-95 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MC49_RS13035 52da99093f05869c12734f7da98b4d1c 158 SUPERFAMILY SSF53955 8 156 2.05E-52 T 29-03-2018 IPR023346 Lysozyme-like domain MC49_RS13035 52da99093f05869c12734f7da98b4d1c 158 Gene3D G3DSA:1.10.530.40 1 157 9.5E-50 T 29-03-2018 IPR023347 Lysozyme domain GO:0003796 MC49_RS13035 52da99093f05869c12734f7da98b4d1c 158 Pfam PF00959 Phage lysozyme 43 148 2.4E-25 T 29-03-2018 IPR002196 Glycoside hydrolase, family 24 GO:0003796|GO:0009253|GO:0016998 MC49_RS08420 eb54f651789731fb492e5b4e9fb098b1 355 Pfam PF11760 Cobalamin synthesis G N-terminal 56 136 8.6E-35 T 29-03-2018 IPR021744 Cobalamin synthesis G, N-terminal KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 MC49_RS08420 eb54f651789731fb492e5b4e9fb098b1 355 SUPERFAMILY SSF159664 226 351 1.31E-32 T 29-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 MC49_RS08420 eb54f651789731fb492e5b4e9fb098b1 355 Pfam PF01890 Cobalamin synthesis G C-terminus 233 348 1.1E-27 T 29-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 MC49_RS08420 eb54f651789731fb492e5b4e9fb098b1 355 SUPERFAMILY SSF159672 9 240 4.84E-55 T 29-03-2018 MC49_RS08420 eb54f651789731fb492e5b4e9fb098b1 355 Gene3D G3DSA:3.30.420.180 223 353 1.3E-31 T 29-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 MC49_RS11795 3142c0fa8ab73a1b0ccd3ecbb8b49d4b 211 Pfam PF03872 Anti sigma-E protein RseA, N-terminal domain 1 86 2.7E-36 T 29-03-2018 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 MC49_RS11795 3142c0fa8ab73a1b0ccd3ecbb8b49d4b 211 Pfam PF03873 Anti sigma-E protein RseA, C-terminal domain 134 186 4.9E-14 T 29-03-2018 IPR005573 Anti sigma-E protein RseA, C-terminal MC49_RS11795 3142c0fa8ab73a1b0ccd3ecbb8b49d4b 211 SUPERFAMILY SSF89069 1 66 5.23E-20 T 29-03-2018 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 MC49_RS14135 1c32f23f401826e13da32ef114802e36 310 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 3 297 1.1E-81 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain MC49_RS14135 1c32f23f401826e13da32ef114802e36 310 ProSitePatterns PS01247 Inosine-uridine preferring nucleoside hydrolase family signature. 7 17 - T 29-03-2018 IPR015910 Inosine/uridine-preferring nucleoside hydrolase, conserved site GO:0016799 MC49_RS14135 1c32f23f401826e13da32ef114802e36 310 Gene3D G3DSA:3.90.245.10 1 309 2.3E-91 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain MC49_RS14135 1c32f23f401826e13da32ef114802e36 310 SUPERFAMILY SSF53590 1 307 1.44E-86 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain MC49_RS07840 d0a3624057f8b874ac31296e1b702a4f 352 Gene3D G3DSA:3.40.190.10 44 190 2.8E-18 T 29-03-2018 MC49_RS07840 d0a3624057f8b874ac31296e1b702a4f 352 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 44 346 1.9E-128 T 29-03-2018 IPR005948 Thiamine/thiamin pyrophosphate-binding periplasmic protein, ABC transporter GO:0015888|GO:0030288|GO:0030975 MC49_RS07840 d0a3624057f8b874ac31296e1b702a4f 352 Pfam PF13343 Bacterial extracellular solute-binding protein 100 332 6.3E-21 T 29-03-2018 MC49_RS07840 d0a3624057f8b874ac31296e1b702a4f 352 Gene3D G3DSA:3.40.190.10 191 329 4.4E-15 T 29-03-2018 MC49_RS07840 d0a3624057f8b874ac31296e1b702a4f 352 SUPERFAMILY SSF53850 47 347 1.63E-64 T 29-03-2018 MC49_RS07840 d0a3624057f8b874ac31296e1b702a4f 352 TIGRFAM TIGR01276 thiB: thiamin/thiamin pyrophosphate ABC transporter, thiamin/thiamin pyrophospate-binding protein 33 352 2.1E-143 T 29-03-2018 IPR005967 Thiamin/thiamin pyrophosphate ABC transporter, substrate-binding protein, Proteobacteria GO:0015888|GO:0030288|GO:0030975 MC49_RS02325 19428bec3d5fed30b37122bfefb5c339 287 TIGRFAM TIGR02790 nickel_nikC: nickel ABC transporter, permease subunit NikC 23 278 1.1E-112 T 29-03-2018 IPR014157 Nickel ABC transporter, permease subunit NikC GO:0015099|GO:0016021 MC49_RS02325 19428bec3d5fed30b37122bfefb5c339 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 282 1.4E-29 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS02325 19428bec3d5fed30b37122bfefb5c339 287 SUPERFAMILY SSF161098 76 263 2.35E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS02325 19428bec3d5fed30b37122bfefb5c339 287 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 11 58 1.4E-8 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain MC49_RS02325 19428bec3d5fed30b37122bfefb5c339 287 Gene3D G3DSA:1.10.3720.10 18 283 5.3E-40 T 29-03-2018 MC49_RS08060 809b463989b5a66e6544f297b603f01b 285 Pfam PF01148 Cytidylyltransferase family 4 278 1.7E-61 T 29-03-2018 MC49_RS08060 809b463989b5a66e6544f297b603f01b 285 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 239 265 - T 29-03-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 MC49_RS18795 f31c37f357d2e2bc9dbf8849e040aac1 473 SUPERFAMILY SSF46785 4 73 8.75E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS18795 f31c37f357d2e2bc9dbf8849e040aac1 473 SMART SM00345 10 69 3.6E-16 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MC49_RS18795 f31c37f357d2e2bc9dbf8849e040aac1 473 Pfam PF00155 Aminotransferase class I and II 148 461 1.4E-26 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MC49_RS18795 f31c37f357d2e2bc9dbf8849e040aac1 473 Gene3D G3DSA:1.10.10.10 3 71 9.1E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS18795 f31c37f357d2e2bc9dbf8849e040aac1 473 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 69 7.4E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MC49_RS18795 f31c37f357d2e2bc9dbf8849e040aac1 473 Gene3D G3DSA:3.40.640.10 141 370 1.4E-42 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS18795 f31c37f357d2e2bc9dbf8849e040aac1 473 SUPERFAMILY SSF53383 147 468 2.72E-75 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS18795 f31c37f357d2e2bc9dbf8849e040aac1 473 Gene3D G3DSA:3.90.1150.10 371 470 7.5E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS04525 27cd9dbaf15a229d02907416721f16e6 461 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 441 461 3.5E-9 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MC49_RS04525 27cd9dbaf15a229d02907416721f16e6 461 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 424 441 3.5E-9 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MC49_RS04525 27cd9dbaf15a229d02907416721f16e6 461 SMART SM00448 7 118 4.2E-37 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS04525 27cd9dbaf15a229d02907416721f16e6 461 SUPERFAMILY SSF52540 149 390 1.13E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS04525 27cd9dbaf15a229d02907416721f16e6 461 SUPERFAMILY SSF46689 360 460 2.69E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS04525 27cd9dbaf15a229d02907416721f16e6 461 Gene3D G3DSA:1.10.10.60 390 461 2.2E-18 T 29-03-2018 MC49_RS04525 27cd9dbaf15a229d02907416721f16e6 461 Gene3D G3DSA:3.40.50.2300 2 142 4.5E-38 T 29-03-2018 MC49_RS04525 27cd9dbaf15a229d02907416721f16e6 461 Gene3D G3DSA:1.10.8.60 319 389 9.4E-26 T 29-03-2018 MC49_RS04525 27cd9dbaf15a229d02907416721f16e6 461 Pfam PF02954 Bacterial regulatory protein, Fis family 421 458 1.5E-12 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MC49_RS04525 27cd9dbaf15a229d02907416721f16e6 461 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 171 184 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MC49_RS04525 27cd9dbaf15a229d02907416721f16e6 461 SUPERFAMILY SSF52172 5 192 1.22E-48 T 29-03-2018 IPR011006 CheY-like superfamily MC49_RS04525 27cd9dbaf15a229d02907416721f16e6 461 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 233 248 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MC49_RS04525 27cd9dbaf15a229d02907416721f16e6 461 Gene3D G3DSA:3.40.50.300 143 318 6.7E-28 T 29-03-2018 MC49_RS04525 27cd9dbaf15a229d02907416721f16e6 461 Pfam PF00072 Response regulator receiver domain 10 116 2.2E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS04525 27cd9dbaf15a229d02907416721f16e6 461 Pfam PF00158 Sigma-54 interaction domain 149 313 4.1E-72 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MC49_RS04525 27cd9dbaf15a229d02907416721f16e6 461 SMART SM00382 167 310 8.9E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS13135 61d3524e3c0b3258190795d732602021 237 Pfam PF14464 Prokaryotic homologs of the JAB domain 3 92 2.2E-8 T 29-03-2018 IPR028090 JAB domain, prokaryotic MC49_RS13135 61d3524e3c0b3258190795d732602021 237 Gene3D G3DSA:3.40.140.10 2 97 2.8E-8 T 29-03-2018 MC49_RS13135 61d3524e3c0b3258190795d732602021 237 SUPERFAMILY SSF102712 6 90 6.67E-13 T 29-03-2018 MC49_RS13135 61d3524e3c0b3258190795d732602021 237 SUPERFAMILY SSF54001 103 223 9.81E-14 T 29-03-2018 MC49_RS13135 61d3524e3c0b3258190795d732602021 237 Pfam PF00877 NlpC/P60 family 105 216 7.0E-13 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain MC49_RS13135 61d3524e3c0b3258190795d732602021 237 Gene3D G3DSA:3.90.1720.10 98 220 1.5E-12 T 29-03-2018 MC49_RS08390 9f1acd6964045395d38a231aaec69300 92 Hamap MF_00330 Cobalt transport protein CbiN [cbiN]. 1 92 40.757 T 29-03-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 MC49_RS08390 9f1acd6964045395d38a231aaec69300 92 Pfam PF02553 Cobalt transport protein component CbiN 5 69 1.3E-28 T 29-03-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 MC49_RS08390 9f1acd6964045395d38a231aaec69300 92 TIGRFAM TIGR01165 cbiN: cobalt transport protein 1 84 4.6E-35 T 29-03-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 MC49_RS01670 3bb036a741e7f623fe2878af39258aed 162 PIRSF PIRSF018472 1 162 1.1E-54 T 29-03-2018 IPR026034 Cell shape-determining protein MreD, proteobacterial type MC49_RS01670 3bb036a741e7f623fe2878af39258aed 162 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 8 154 9.3E-41 T 29-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 MC49_RS01670 3bb036a741e7f623fe2878af39258aed 162 Pfam PF04093 rod shape-determining protein MreD 6 154 1.6E-38 T 29-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 MC49_RS10640 625cb06a31112f620403fdb62f14b6b0 365 Pfam PF12698 ABC-2 family transporter protein 24 356 2.4E-44 T 29-03-2018 MC49_RS10640 625cb06a31112f620403fdb62f14b6b0 365 Gene3D G3DSA:3.40.1710.10 38 185 7.4E-27 T 29-03-2018 MC49_RS14290 4cde0106055e0f2ec0f3d515ae4a61b4 339 Gene3D G3DSA:1.10.3470.10 1 338 4.2E-71 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like MC49_RS14290 4cde0106055e0f2ec0f3d515ae4a61b4 339 Pfam PF01032 FecCD transport family 14 329 3.7E-87 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 MC49_RS14290 4cde0106055e0f2ec0f3d515ae4a61b4 339 SUPERFAMILY SSF81345 3 329 5.62E-77 T 29-03-2018 IPR029022 ABC transporter, BtuC-like MC49_RS11870 427f6de8abfb5fbdac9b3ddd6c4f6e81 126 Gene3D G3DSA:3.10.180.10 2 121 2.0E-16 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MC49_RS11870 427f6de8abfb5fbdac9b3ddd6c4f6e81 126 PIRSF PIRSF039020 1 122 1.5E-43 T 29-03-2018 IPR026275 Glyoxalase/dioxygenase/EhpR MC49_RS11870 427f6de8abfb5fbdac9b3ddd6c4f6e81 126 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 115 1.7E-7 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MC49_RS11870 427f6de8abfb5fbdac9b3ddd6c4f6e81 126 SUPERFAMILY SSF54593 3 120 1.05E-19 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MC49_RS03800 f9edaf4d955d2d64f64ee96009905809 376 Gene3D G3DSA:3.40.640.10 1 242 1.0E-47 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS03800 f9edaf4d955d2d64f64ee96009905809 376 Hamap MF_02026 dTDP-4-amino-4,6-dideoxygalactose transaminase [wecE]. 1 376 79.164 T 29-03-2018 IPR032894 dTDP-4-amino-4,6-dideoxygalactose transaminase WecE GO:0009246|GO:0019180 MetaCyc: PWY-7315 MC49_RS03800 f9edaf4d955d2d64f64ee96009905809 376 SUPERFAMILY SSF53383 2 375 2.96E-104 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS03800 f9edaf4d955d2d64f64ee96009905809 376 PIRSF PIRSF000390 1 376 6.4E-116 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase MC49_RS03800 f9edaf4d955d2d64f64ee96009905809 376 Gene3D G3DSA:3.90.1150.10 243 376 6.4E-29 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS03800 f9edaf4d955d2d64f64ee96009905809 376 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 13 371 9.3E-89 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase MC49_RS03800 f9edaf4d955d2d64f64ee96009905809 376 TIGRFAM TIGR02379 ECA_wecE: TDP-4-keto-6-deoxy-D-glucose transaminase 1 374 9.3E-214 T 29-03-2018 IPR012749 dTDP-4-amino-4,6-dideoxygalactose transaminase WecE-like MetaCyc: PWY-7315 MC49_RS07830 5d9d44fd80d14f235646cdceb3818060 232 Gene3D G3DSA:3.40.50.300 1 226 8.1E-55 T 29-03-2018 MC49_RS07830 5d9d44fd80d14f235646cdceb3818060 232 SMART SM00382 24 207 2.4E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS07830 5d9d44fd80d14f235646cdceb3818060 232 TIGRFAM TIGR01277 thiQ: thiamine ABC transporter, ATP-binding protein 2 211 1.6E-97 T 29-03-2018 IPR005968 Thiamine ABC transporter, ATP-binding protein ThiQ GO:0005524|GO:0006810|GO:0016021|GO:0042626 MC49_RS07830 5d9d44fd80d14f235646cdceb3818060 232 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS07830 5d9d44fd80d14f235646cdceb3818060 232 SUPERFAMILY SSF52540 1 219 7.38E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS07830 5d9d44fd80d14f235646cdceb3818060 232 Pfam PF00005 ABC transporter 17 157 7.7E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS10805 d1440de05de97728aa0ee3a1a3c4e44e 214 Hamap MF_00551 Uridine kinase [udk]. 6 214 40.034 T 29-03-2018 IPR026008 Uridine kinase GO:0004849|GO:0005524|GO:0016773 KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 MC49_RS10805 d1440de05de97728aa0ee3a1a3c4e44e 214 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 11 200 5.2E-45 T 29-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 MC49_RS10805 d1440de05de97728aa0ee3a1a3c4e44e 214 SUPERFAMILY SSF52540 8 206 7.56E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS10805 d1440de05de97728aa0ee3a1a3c4e44e 214 PRINTS PR00988 Uridine kinase signature 43 54 7.0E-37 T 29-03-2018 MC49_RS10805 d1440de05de97728aa0ee3a1a3c4e44e 214 PRINTS PR00988 Uridine kinase signature 180 193 7.0E-37 T 29-03-2018 MC49_RS10805 d1440de05de97728aa0ee3a1a3c4e44e 214 PRINTS PR00988 Uridine kinase signature 9 26 7.0E-37 T 29-03-2018 MC49_RS10805 d1440de05de97728aa0ee3a1a3c4e44e 214 PRINTS PR00988 Uridine kinase signature 144 154 7.0E-37 T 29-03-2018 MC49_RS10805 d1440de05de97728aa0ee3a1a3c4e44e 214 PRINTS PR00988 Uridine kinase signature 88 103 7.0E-37 T 29-03-2018 MC49_RS10805 d1440de05de97728aa0ee3a1a3c4e44e 214 PRINTS PR00988 Uridine kinase signature 158 169 7.0E-37 T 29-03-2018 MC49_RS10805 d1440de05de97728aa0ee3a1a3c4e44e 214 TIGRFAM TIGR00235 udk: uridine kinase 6 213 6.5E-91 T 29-03-2018 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|Reactome: R-HSA-73614 MC49_RS10805 d1440de05de97728aa0ee3a1a3c4e44e 214 Gene3D G3DSA:3.40.50.300 5 214 2.2E-59 T 29-03-2018 MC49_RS04670 3ac12574e4d26839b0a9beda598bd7d4 281 Gene3D G3DSA:3.30.70.20 221 278 6.5E-6 T 29-03-2018 MC49_RS04670 3ac12574e4d26839b0a9beda598bd7d4 281 Pfam PF00037 4Fe-4S binding domain 34 57 7.8E-7 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MC49_RS04670 3ac12574e4d26839b0a9beda598bd7d4 281 Pfam PF00037 4Fe-4S binding domain 181 202 4.2E-5 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MC49_RS04670 3ac12574e4d26839b0a9beda598bd7d4 281 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 41 52 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MC49_RS04670 3ac12574e4d26839b0a9beda598bd7d4 281 Gene3D G3DSA:3.30.70.20 194 220 7.5E-11 T 29-03-2018 MC49_RS04670 3ac12574e4d26839b0a9beda598bd7d4 281 Gene3D G3DSA:3.30.70.20 2 45 8.0E-9 T 29-03-2018 MC49_RS04670 3ac12574e4d26839b0a9beda598bd7d4 281 Gene3D G3DSA:3.30.70.20 46 193 7.4E-18 T 29-03-2018 MC49_RS04670 3ac12574e4d26839b0a9beda598bd7d4 281 SUPERFAMILY SSF54862 14 85 5.18E-15 T 29-03-2018 MC49_RS04670 3ac12574e4d26839b0a9beda598bd7d4 281 SUPERFAMILY SSF54862 168 236 1.84E-15 T 29-03-2018 MC49_RS03580 81cd63ef9cfd6925f13d4c6896c47bba 337 SUPERFAMILY SSF117892 194 231 8.76E-8 T 29-03-2018 IPR001107 Band 7 domain MC49_RS03580 81cd63ef9cfd6925f13d4c6896c47bba 337 Pfam PF01145 SPFH domain / Band 7 family 22 240 5.4E-35 T 29-03-2018 IPR001107 Band 7 domain MC49_RS03580 81cd63ef9cfd6925f13d4c6896c47bba 337 PIRSF PIRSF005651 1 333 1.6E-100 T 29-03-2018 IPR010200 HflC GO:0016021|GO:0052547 MC49_RS03580 81cd63ef9cfd6925f13d4c6896c47bba 337 SUPERFAMILY SSF117892 56 157 2.35E-16 T 29-03-2018 IPR001107 Band 7 domain MC49_RS03580 81cd63ef9cfd6925f13d4c6896c47bba 337 TIGRFAM TIGR01932 hflC: HflC protein 1 326 3.1E-124 T 29-03-2018 IPR010200 HflC GO:0016021|GO:0052547 MC49_RS03580 81cd63ef9cfd6925f13d4c6896c47bba 337 SMART SM00244 18 225 1.7E-39 T 29-03-2018 IPR001107 Band 7 domain MC49_RS03580 81cd63ef9cfd6925f13d4c6896c47bba 337 Gene3D G3DSA:1.10.533.10 227 306 0.0087 T 29-03-2018 MC49_RS16185 0b6b9c3950b59f51ce567fcadaa08d27 1763 SMART SM00912 39 159 6.9E-33 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal MC49_RS16185 0b6b9c3950b59f51ce567fcadaa08d27 1763 Pfam PF04830 Possible hemagglutinin (DUF637) 1224 1388 7.0E-48 T 29-03-2018 IPR006915 Domain of unknown function DUF637, haemagglutinin putative MC49_RS16185 0b6b9c3950b59f51ce567fcadaa08d27 1763 Pfam PF05860 haemagglutination activity domain 37 157 1.3E-27 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal MC49_RS16185 0b6b9c3950b59f51ce567fcadaa08d27 1763 Gene3D G3DSA:2.160.20.10 25 361 1.4E-41 T 29-03-2018 IPR012334 Pectin lyase fold MC49_RS16185 0b6b9c3950b59f51ce567fcadaa08d27 1763 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 57 153 4.2E-17 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal MC49_RS16185 0b6b9c3950b59f51ce567fcadaa08d27 1763 Gene3D G3DSA:2.160.20.10 603 818 4.5E-9 T 29-03-2018 IPR012334 Pectin lyase fold MC49_RS16185 0b6b9c3950b59f51ce567fcadaa08d27 1763 SUPERFAMILY SSF51126 40 310 1.13E-46 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor MC49_RS16155 d916c455d8a49a49f9104508027f1770 156 SUPERFAMILY SSF52833 3 155 4.02E-48 T 29-03-2018 IPR012336 Thioredoxin-like fold MC49_RS16155 d916c455d8a49a49f9104508027f1770 156 Pfam PF00578 AhpC/TSA family 7 134 2.9E-38 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MC49_RS16155 d916c455d8a49a49f9104508027f1770 156 Gene3D G3DSA:3.40.30.10 1 154 3.2E-40 T 29-03-2018 MC49_RS05745 124e0e8a7672c19fc672534093b8f422 390 SUPERFAMILY SSF53756 3 376 2.04E-97 T 29-03-2018 MC49_RS05745 124e0e8a7672c19fc672534093b8f422 390 Gene3D G3DSA:3.40.50.2000 1 206 1.1E-45 T 29-03-2018 MC49_RS05745 124e0e8a7672c19fc672534093b8f422 390 TIGRFAM TIGR03568 NeuC_NnaA: UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing 4 370 5.6E-142 T 29-03-2018 IPR020004 UDP-N-acetylglucosamine 2-epimerase,UDP-hydrolysing GO:0004553|GO:0006047 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-4085001 MC49_RS05745 124e0e8a7672c19fc672534093b8f422 390 Gene3D G3DSA:3.40.50.2000 207 346 5.0E-24 T 29-03-2018 MC49_RS05745 124e0e8a7672c19fc672534093b8f422 390 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 25 371 6.8E-88 T 29-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 MC49_RS14205 e6e7375014b114aee576ba6b31daa007 114 SUPERFAMILY SSF55298 1 114 7.7E-29 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like MC49_RS14205 e6e7375014b114aee576ba6b31daa007 114 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 90 108 - T 29-03-2018 IPR019897 RidA, conserved site MC49_RS14205 e6e7375014b114aee576ba6b31daa007 114 Pfam PF01042 Endoribonuclease L-PSP 3 114 7.5E-28 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family MC49_RS14205 e6e7375014b114aee576ba6b31daa007 114 Gene3D G3DSA:3.30.1330.40 2 114 2.6E-24 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like MC49_RS18800 e7a42b88257635be6621d15a7765ae5e 293 Gene3D G3DSA:2.60.120.10 1 261 2.2E-72 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MC49_RS18800 e7a42b88257635be6621d15a7765ae5e 293 SUPERFAMILY SSF51182 4 292 2.78E-79 T 29-03-2018 IPR011051 RmlC-like cupin domain MC49_RS18800 e7a42b88257635be6621d15a7765ae5e 293 Pfam PF02678 Pirin 20 128 9.9E-33 T 29-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 MC49_RS18800 e7a42b88257635be6621d15a7765ae5e 293 Pfam PF05726 Pirin C-terminal cupin domain 183 288 1.0E-23 T 29-03-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 MC49_RS18800 e7a42b88257635be6621d15a7765ae5e 293 PIRSF PIRSF006232 2 293 1.1E-82 T 29-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 MC49_RS03360 b3654b3c543d42d48031d7e179d51561 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 6.0E-34 T 29-03-2018 MC49_RS03360 b3654b3c543d42d48031d7e179d51561 89 Gene3D G3DSA:1.10.287.10 2 89 1.5E-35 T 29-03-2018 MC49_RS03360 b3654b3c543d42d48031d7e179d51561 89 SMART SM01387 8 88 7.4E-51 T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS03360 b3654b3c543d42d48031d7e179d51561 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS03360 b3654b3c543d42d48031d7e179d51561 89 SUPERFAMILY SSF47060 3 89 3.24E-34 T 29-03-2018 IPR009068 S15/NS1, RNA-binding MC49_RS03360 b3654b3c543d42d48031d7e179d51561 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 21.659 T 29-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS03360 b3654b3c543d42d48031d7e179d51561 89 Pfam PF00312 Ribosomal protein S15 8 88 2.4E-36 T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS03360 b3654b3c543d42d48031d7e179d51561 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 6.2E-39 T 29-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS14165 97d44cc31acf78ccdff9197efe950363 99 Hamap MF_02051 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase [lsrG]. 1 96 36.751 T 29-03-2018 IPR033672 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase GO:0016853 MC49_RS14165 97d44cc31acf78ccdff9197efe950363 99 SUPERFAMILY SSF54909 4 91 7.51E-26 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel MC49_RS14165 97d44cc31acf78ccdff9197efe950363 99 Gene3D G3DSA:3.30.70.100 2 91 2.3E-23 T 29-03-2018 MC49_RS14165 97d44cc31acf78ccdff9197efe950363 99 Pfam PF03992 Antibiotic biosynthesis monooxygenase 5 76 1.5E-18 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain MC49_RS11225 f938dff37073a264642edabebfa8d77d 375 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 155 166 1.1E-12 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 MC49_RS11225 f938dff37073a264642edabebfa8d77d 375 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 245 257 1.1E-12 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 MC49_RS11225 f938dff37073a264642edabebfa8d77d 375 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 327 344 1.1E-12 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 MC49_RS11225 f938dff37073a264642edabebfa8d77d 375 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 98 108 1.1E-12 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 MC49_RS11225 f938dff37073a264642edabebfa8d77d 375 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 56 67 1.1E-12 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 MC49_RS11225 f938dff37073a264642edabebfa8d77d 375 PRINTS PR00183 E.coli/Salmonella-type porin signature 22 38 8.4E-64 T 29-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 MC49_RS11225 f938dff37073a264642edabebfa8d77d 375 PRINTS PR00183 E.coli/Salmonella-type porin signature 55 73 8.4E-64 T 29-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 MC49_RS11225 f938dff37073a264642edabebfa8d77d 375 PRINTS PR00183 E.coli/Salmonella-type porin signature 153 175 8.4E-64 T 29-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 MC49_RS11225 f938dff37073a264642edabebfa8d77d 375 PRINTS PR00183 E.coli/Salmonella-type porin signature 98 120 8.4E-64 T 29-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 MC49_RS11225 f938dff37073a264642edabebfa8d77d 375 PRINTS PR00183 E.coli/Salmonella-type porin signature 251 268 8.4E-64 T 29-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 MC49_RS11225 f938dff37073a264642edabebfa8d77d 375 PRINTS PR00183 E.coli/Salmonella-type porin signature 281 300 8.4E-64 T 29-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 MC49_RS11225 f938dff37073a264642edabebfa8d77d 375 Pfam PF00267 Gram-negative porin 27 375 4.5E-131 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 MC49_RS11225 f938dff37073a264642edabebfa8d77d 375 Gene3D G3DSA:2.40.160.10 10 375 2.0E-55 T 29-03-2018 MC49_RS11225 f938dff37073a264642edabebfa8d77d 375 SUPERFAMILY SSF56935 22 375 1.52E-79 T 29-03-2018 MC49_RS12340 c5c92e957f314030bee9274943c17a5c 584 PRINTS PR00344 Bacterial sensor protein C-terminal signature 534 552 1.7E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS12340 c5c92e957f314030bee9274943c17a5c 584 PRINTS PR00344 Bacterial sensor protein C-terminal signature 523 533 1.7E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS12340 c5c92e957f314030bee9274943c17a5c 584 PRINTS PR00344 Bacterial sensor protein C-terminal signature 505 519 1.7E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS12340 c5c92e957f314030bee9274943c17a5c 584 Gene3D G3DSA:1.10.287.130 329 420 5.5E-7 T 29-03-2018 MC49_RS12340 c5c92e957f314030bee9274943c17a5c 584 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 475 574 7.6E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS12340 c5c92e957f314030bee9274943c17a5c 584 Gene3D G3DSA:3.40.190.10 122 266 5.2E-17 T 29-03-2018 MC49_RS12340 c5c92e957f314030bee9274943c17a5c 584 SUPERFAMILY SSF47384 345 420 9.61E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS12340 c5c92e957f314030bee9274943c17a5c 584 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 28 260 4.8E-31 T 29-03-2018 MC49_RS12340 c5c92e957f314030bee9274943c17a5c 584 SMART SM00387 470 578 3.9E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS12340 c5c92e957f314030bee9274943c17a5c 584 SMART SM00388 356 424 0.0047 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS12340 c5c92e957f314030bee9274943c17a5c 584 SUPERFAMILY SSF53850 44 260 5.08E-15 T 29-03-2018 MC49_RS12340 c5c92e957f314030bee9274943c17a5c 584 Gene3D G3DSA:3.30.565.10 432 581 8.7E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS12340 c5c92e957f314030bee9274943c17a5c 584 SUPERFAMILY SSF55874 433 574 7.2E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS12585 9116baba740170ce3b35a5c9ab906a06 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 87 7.7E-31 T 29-03-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 MC49_RS12585 9116baba740170ce3b35a5c9ab906a06 89 Pfam PF01313 Bacterial export proteins, family 3 6 77 1.0E-28 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 MC49_RS12585 9116baba740170ce3b35a5c9ab906a06 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 6.4E-22 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 MC49_RS12585 9116baba740170ce3b35a5c9ab906a06 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 6.4E-22 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 MC49_RS12585 9116baba740170ce3b35a5c9ab906a06 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 6.4E-22 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 MC49_RS12585 9116baba740170ce3b35a5c9ab906a06 89 PIRSF PIRSF004669 1 89 1.1E-30 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 MC49_RS05650 d8f9d0bc5baf8131b037e49140a5c830 157 Hamap MF_00821 Protein-export protein SecB [secB]. 1 145 33.462 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MC49_RS05650 d8f9d0bc5baf8131b037e49140a5c830 157 TIGRFAM TIGR00809 secB: protein-export chaperone SecB 6 144 3.5E-66 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MC49_RS05650 d8f9d0bc5baf8131b037e49140a5c830 157 SUPERFAMILY SSF54611 2 141 3.71E-53 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MC49_RS05650 d8f9d0bc5baf8131b037e49140a5c830 157 Gene3D G3DSA:3.10.420.10 1 153 1.9E-56 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MC49_RS05650 d8f9d0bc5baf8131b037e49140a5c830 157 Pfam PF02556 Preprotein translocase subunit SecB 4 144 2.9E-57 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MC49_RS05650 d8f9d0bc5baf8131b037e49140a5c830 157 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 73 93 1.2E-40 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MC49_RS05650 d8f9d0bc5baf8131b037e49140a5c830 157 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 13 30 1.2E-40 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MC49_RS05650 d8f9d0bc5baf8131b037e49140a5c830 157 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 123 141 1.2E-40 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MC49_RS05650 d8f9d0bc5baf8131b037e49140a5c830 157 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 97 119 1.2E-40 T 29-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MC49_RS14930 c9470ed7fe289f7bbfe7500fbdafc893 483 SUPERFAMILY SSF103378 12 482 3.27E-167 T 29-03-2018 IPR005656 MmgE/PrpD GO:0016829 MC49_RS14930 c9470ed7fe289f7bbfe7500fbdafc893 483 Gene3D G3DSA:1.10.4100.10 2 331 1.4E-105 T 29-03-2018 MC49_RS14930 c9470ed7fe289f7bbfe7500fbdafc893 483 Pfam PF03972 MmgE/PrpD family 17 464 1.5E-164 T 29-03-2018 IPR005656 MmgE/PrpD GO:0016829 MC49_RS14930 c9470ed7fe289f7bbfe7500fbdafc893 483 TIGRFAM TIGR02330 prpD: 2-methylcitrate dehydratase 13 483 4.3E-260 T 29-03-2018 IPR012705 2-methylcitrate dehydratase PrpD GO:0019629|GO:0047547|GO:0051537 KEGG: 00640+4.2.1.79 MC49_RS14930 c9470ed7fe289f7bbfe7500fbdafc893 483 Gene3D G3DSA:1.10.4100.10 385 483 9.3E-14 T 29-03-2018 MC49_RS01615 4bcd257f7c0819bfda72fed70a59bc0a 705 SUPERFAMILY SSF56935 30 705 5.19E-112 T 29-03-2018 MC49_RS01615 4bcd257f7c0819bfda72fed70a59bc0a 705 Gene3D G3DSA:2.170.130.10 29 170 1.0E-21 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MC49_RS01615 4bcd257f7c0819bfda72fed70a59bc0a 705 Pfam PF00593 TonB dependent receptor 234 703 2.3E-55 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MC49_RS01615 4bcd257f7c0819bfda72fed70a59bc0a 705 Pfam PF07715 TonB-dependent Receptor Plug Domain 66 163 3.4E-15 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MC49_RS01615 4bcd257f7c0819bfda72fed70a59bc0a 705 Gene3D G3DSA:2.40.170.20 171 705 4.2E-69 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MC49_RS01615 4bcd257f7c0819bfda72fed70a59bc0a 705 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 42 - T 29-03-2018 IPR010916 TonB box, conserved site MC49_RS01615 4bcd257f7c0819bfda72fed70a59bc0a 705 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 67 705 1.4E-92 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 MC49_RS03970 94cfe155a9ac8a133b0acebdb2e92335 87 Pfam PF07369 Protein of unknown function (DUF1488) 5 77 4.0E-19 T 29-03-2018 IPR009962 Protein of unknown function DUF1488 MC49_RS03970 94cfe155a9ac8a133b0acebdb2e92335 87 Gene3D G3DSA:3.30.160.140 5 79 5.5E-21 T 29-03-2018 IPR009962 Protein of unknown function DUF1488 MC49_RS03970 94cfe155a9ac8a133b0acebdb2e92335 87 SUPERFAMILY SSF160272 1 78 5.23E-24 T 29-03-2018 IPR009962 Protein of unknown function DUF1488 MC49_RS18375 ed7088991ef1d70e8267cf09638772af 522 Pfam PF00589 Phage integrase family 318 505 3.5E-16 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MC49_RS18375 ed7088991ef1d70e8267cf09638772af 522 Gene3D G3DSA:1.10.443.10 313 519 3.7E-22 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MC49_RS18375 ed7088991ef1d70e8267cf09638772af 522 Gene3D G3DSA:1.10.150.130 173 312 1.0E-10 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal MC49_RS18375 ed7088991ef1d70e8267cf09638772af 522 SUPERFAMILY SSF56349 265 509 5.89E-35 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MC49_RS18375 ed7088991ef1d70e8267cf09638772af 522 SUPERFAMILY SSF56349 177 236 5.89E-35 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MC49_RS08240 e64f1fb4e44762c85d4fd6ae2bff5912 131 ProDom PD031420 YFEK EXPORTED PRECURSOR SIGNAL PERIPLASMIC ECS3291 XCC0326 28 114 1.0E-14 T 29-03-2018 IPR035242 Protein of unknown function DUF5329 MC49_RS08240 e64f1fb4e44762c85d4fd6ae2bff5912 131 Pfam PF17263 Family of unknown function (DUF5329) 31 122 2.2E-31 T 29-03-2018 IPR035242 Protein of unknown function DUF5329 MC49_RS06655 620599b1988c6229fd2e9058e6850b57 172 Gene3D G3DSA:1.10.10.10 1 91 4.3E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS06655 620599b1988c6229fd2e9058e6850b57 172 SUPERFAMILY SSF46785 12 144 1.31E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS06655 620599b1988c6229fd2e9058e6850b57 172 Pfam PF01475 Ferric uptake regulator family 20 138 5.6E-13 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 MC49_RS07485 797a9c3bd1daa647c4c6ed4dba0e719e 287 Gene3D G3DSA:1.10.10.60 234 286 3.2E-13 T 29-03-2018 MC49_RS07485 797a9c3bd1daa647c4c6ed4dba0e719e 287 SMART SM00342 200 283 6.3E-15 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MC49_RS07485 797a9c3bd1daa647c4c6ed4dba0e719e 287 Pfam PF12833 Helix-turn-helix domain 206 285 3.2E-15 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MC49_RS07485 797a9c3bd1daa647c4c6ed4dba0e719e 287 SUPERFAMILY SSF46689 236 285 1.21E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS07485 797a9c3bd1daa647c4c6ed4dba0e719e 287 Gene3D G3DSA:2.60.120.280 28 169 4.0E-5 T 29-03-2018 MC49_RS07485 797a9c3bd1daa647c4c6ed4dba0e719e 287 Gene3D G3DSA:1.10.10.60 174 233 0.0013 T 29-03-2018 MC49_RS11005 645b8c7672f62e543e925e337b0d0a51 299 ProDom PD022789 MEMBRANE SURFACE PRECURSOR SIGNAL PROTEIN YBJE TRANSMEMBRANE INNER PREDICTED STY0934 138 299 1.0E-51 T 29-03-2018 IPR005642 Lysine exporter LysO MC49_RS11005 645b8c7672f62e543e925e337b0d0a51 299 Pfam PF03956 Lysine exporter LysO 114 298 1.3E-56 T 29-03-2018 IPR005642 Lysine exporter LysO MC49_RS11140 898428df229daa5c066d50418d864dbb 766 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 238 429 2.9E-31 T 29-03-2018 IPR004477 ComEC/Rec2-related protein MC49_RS11140 898428df229daa5c066d50418d864dbb 766 Pfam PF00753 Metallo-beta-lactamase superfamily 525 689 3.4E-11 T 29-03-2018 IPR001279 Metallo-beta-lactamase MC49_RS11140 898428df229daa5c066d50418d864dbb 766 Gene3D G3DSA:3.60.15.10 511 746 1.3E-22 T 29-03-2018 IPR001279 Metallo-beta-lactamase MC49_RS11140 898428df229daa5c066d50418d864dbb 766 SUPERFAMILY SSF56281 512 749 2.36E-41 T 29-03-2018 IPR001279 Metallo-beta-lactamase MC49_RS11140 898428df229daa5c066d50418d864dbb 766 SMART SM00849 523 701 1.2E-7 T 29-03-2018 IPR001279 Metallo-beta-lactamase MC49_RS11140 898428df229daa5c066d50418d864dbb 766 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 141 730 6.7E-138 T 29-03-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 MC49_RS11140 898428df229daa5c066d50418d864dbb 766 Pfam PF03772 Competence protein 217 482 9.2E-48 T 29-03-2018 IPR004477 ComEC/Rec2-related protein MC49_RS02825 f7ca9c22d525292a8f1e87607f494e29 371 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 41 365 3.5E-158 T 29-03-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 MC49_RS02825 f7ca9c22d525292a8f1e87607f494e29 371 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS02825 f7ca9c22d525292a8f1e87607f494e29 371 SMART SM00382 35 218 1.9E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS02825 f7ca9c22d525292a8f1e87607f494e29 371 SUPERFAMILY SSF52540 10 250 6.06E-89 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS02825 f7ca9c22d525292a8f1e87607f494e29 371 Pfam PF08402 TOBE domain 285 365 8.1E-8 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 MC49_RS02825 f7ca9c22d525292a8f1e87607f494e29 371 Gene3D G3DSA:3.40.50.300 7 271 1.6E-78 T 29-03-2018 MC49_RS02825 f7ca9c22d525292a8f1e87607f494e29 371 SUPERFAMILY SSF50331 243 365 7.37E-8 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal MC49_RS02825 f7ca9c22d525292a8f1e87607f494e29 371 Pfam PF00005 ABC transporter 27 167 7.1E-37 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS06110 891c5e2a9c2dfa6a010fdab41369fb1d 425 SMART SM00912 40 141 4.8E-13 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal MC49_RS06110 891c5e2a9c2dfa6a010fdab41369fb1d 425 Pfam PF05860 haemagglutination activity domain 37 136 3.0E-22 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal MC49_RS06110 891c5e2a9c2dfa6a010fdab41369fb1d 425 SUPERFAMILY SSF51126 32 316 3.14E-31 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor MC49_RS06110 891c5e2a9c2dfa6a010fdab41369fb1d 425 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 59 135 6.5E-20 T 29-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal MC49_RS06110 891c5e2a9c2dfa6a010fdab41369fb1d 425 Gene3D G3DSA:2.160.20.10 27 312 4.0E-30 T 29-03-2018 IPR012334 Pectin lyase fold MC49_RS05850 3741d7acbfd68ee3b6907eec1db914c4 177 Hamap MF_00471 Regulator of ribonuclease activity A [rraA]. 4 164 44.46 T 29-03-2018 IPR014339 Regulator of ribonuclease activity A, gammaproteobacteria GO:0008428|GO:0051252 MC49_RS05850 3741d7acbfd68ee3b6907eec1db914c4 177 Pfam PF03737 Aldolase/RraA 8 155 1.8E-36 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein MC49_RS05850 3741d7acbfd68ee3b6907eec1db914c4 177 Gene3D G3DSA:3.50.30.40 3 164 8.4E-37 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein MC49_RS05850 3741d7acbfd68ee3b6907eec1db914c4 177 SUPERFAMILY SSF89562 6 160 2.22E-43 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein MC49_RS05850 3741d7acbfd68ee3b6907eec1db914c4 177 TIGRFAM TIGR02998 RraA_entero: regulator of ribonuclease activity A 6 162 2.2E-81 T 29-03-2018 IPR014339 Regulator of ribonuclease activity A, gammaproteobacteria GO:0008428|GO:0051252 MC49_RS05850 3741d7acbfd68ee3b6907eec1db914c4 177 TIGRFAM TIGR01935 NOT-MenG: RraA family 8 157 2.6E-62 T 29-03-2018 IPR010203 Regulator of ribonuclease activity A GO:0008428|GO:0051252 MC49_RS11030 45a844d9be1b00f62d3f991e4192c26b 106 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 24 102 1.8E-31 T 29-03-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 MC49_RS11030 45a844d9be1b00f62d3f991e4192c26b 106 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 6 101 27.408 T 29-03-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS MC49_RS11030 45a844d9be1b00f62d3f991e4192c26b 106 SUPERFAMILY SSF54736 21 105 5.75E-32 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like MC49_RS11030 45a844d9be1b00f62d3f991e4192c26b 106 Gene3D G3DSA:3.30.1390.10 13 105 1.7E-33 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like MC49_RS01950 9f48755a31fd711c06bea10005bfe813 112 SUPERFAMILY SSF75005 26 101 6.6E-13 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain MC49_RS01950 9f48755a31fd711c06bea10005bfe813 112 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 27 101 2.9E-9 T 29-03-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal MC49_RS01950 9f48755a31fd711c06bea10005bfe813 112 Gene3D G3DSA:2.115.10.20 15 106 2.9E-9 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain MC49_RS18880 239fb4cb03bdcf5b60a6b54cc0c31de4 353 SUPERFAMILY SSF54631 36 174 2.02E-22 T 29-03-2018 MC49_RS18880 239fb4cb03bdcf5b60a6b54cc0c31de4 353 Gene3D G3DSA:3.10.580.10 32 158 2.4E-17 T 29-03-2018 MC49_RS18880 239fb4cb03bdcf5b60a6b54cc0c31de4 353 SUPERFAMILY SSF161093 178 348 4.32E-46 T 29-03-2018 MC49_RS18880 239fb4cb03bdcf5b60a6b54cc0c31de4 353 Pfam PF01769 Divalent cation transporter 221 342 2.4E-26 T 29-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 MC49_RS18880 239fb4cb03bdcf5b60a6b54cc0c31de4 353 Pfam PF00571 CBS domain 36 94 0.0045 T 29-03-2018 IPR000644 CBS domain MC49_RS18880 239fb4cb03bdcf5b60a6b54cc0c31de4 353 Pfam PF00571 CBS domain 100 154 1.8E-6 T 29-03-2018 IPR000644 CBS domain MC49_RS18880 239fb4cb03bdcf5b60a6b54cc0c31de4 353 Gene3D G3DSA:1.10.357.20 177 352 8.7E-40 T 29-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 MC49_RS17715 43f31e00dbfc3f9b36af092b660155f9 103 Gene3D G3DSA:3.30.50.20 21 98 2.2E-7 T 29-03-2018 MC49_RS17715 43f31e00dbfc3f9b36af092b660155f9 103 Pfam PF16786 Recombination enhancement, RecA-dependent nuclease 7 73 2.5E-12 T 29-03-2018 IPR031875 Recombination enhancement, RecA-dependent nuclease MC49_RS12730 c2c9e73d3a72f64b30a43a4f13143a04 465 Pfam PF00324 Amino acid permease 22 455 6.7E-109 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 MC49_RS12730 c2c9e73d3a72f64b30a43a4f13143a04 465 PIRSF PIRSF006060 1 460 7.6E-65 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MC49_RS12730 c2c9e73d3a72f64b30a43a4f13143a04 465 ProSitePatterns PS00218 Amino acid permeases signature. 47 77 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 MC49_RS03325 1b0ca5aadd8172c803d9059c118f9655 380 Pfam PF12698 ABC-2 family transporter protein 29 357 1.6E-20 T 29-03-2018 MC49_RS03325 1b0ca5aadd8172c803d9059c118f9655 380 Gene3D G3DSA:3.40.1710.10 47 202 4.8E-21 T 29-03-2018 MC49_RS05635 4268de62634f65c07b402d2c857b79fc 357 SUPERFAMILY SSF88713 31 243 4.22E-69 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MC49_RS05635 4268de62634f65c07b402d2c857b79fc 357 Gene3D G3DSA:3.20.20.370 23 247 2.3E-78 T 29-03-2018 MC49_RS05635 4268de62634f65c07b402d2c857b79fc 357 Pfam PF04748 Divergent polysaccharide deacetylase 34 240 2.4E-74 T 29-03-2018 IPR006837 Divergent polysaccharide deacetylase MC49_RS01440 b35aac5302ddf5932415e6823864dc33 472 TIGRFAM TIGR01318 gltD_gamma_fam: glutamate synthase, small subunit 6 472 6.7E-240 T 29-03-2018 IPR006006 Glutamate synthase, NADH/NADPH, small subunit 2 GO:0006537|GO:0016639 MC49_RS01440 b35aac5302ddf5932415e6823864dc33 472 SUPERFAMILY SSF46548 7 157 1.15E-40 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MC49_RS01440 b35aac5302ddf5932415e6823864dc33 472 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 25 134 2.3E-37 T 29-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 MC49_RS01440 b35aac5302ddf5932415e6823864dc33 472 Gene3D G3DSA:3.50.50.60 316 401 5.7E-15 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS01440 b35aac5302ddf5932415e6823864dc33 472 Gene3D G3DSA:3.50.50.60 242 315 1.9E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS01440 b35aac5302ddf5932415e6823864dc33 472 Gene3D G3DSA:3.50.50.60 404 472 1.2E-8 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS01440 b35aac5302ddf5932415e6823864dc33 472 PRINTS PR00419 Adrenodoxin reductase family signature 290 304 6.2E-36 T 29-03-2018 MC49_RS01440 b35aac5302ddf5932415e6823864dc33 472 PRINTS PR00419 Adrenodoxin reductase family signature 148 170 6.2E-36 T 29-03-2018 MC49_RS01440 b35aac5302ddf5932415e6823864dc33 472 PRINTS PR00419 Adrenodoxin reductase family signature 171 184 6.2E-36 T 29-03-2018 MC49_RS01440 b35aac5302ddf5932415e6823864dc33 472 PRINTS PR00419 Adrenodoxin reductase family signature 213 223 6.2E-36 T 29-03-2018 MC49_RS01440 b35aac5302ddf5932415e6823864dc33 472 PRINTS PR00419 Adrenodoxin reductase family signature 324 337 6.2E-36 T 29-03-2018 MC49_RS01440 b35aac5302ddf5932415e6823864dc33 472 Gene3D G3DSA:3.40.50.720 143 241 8.7E-17 T 29-03-2018 MC49_RS01440 b35aac5302ddf5932415e6823864dc33 472 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 148 459 9.7E-28 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS01440 b35aac5302ddf5932415e6823864dc33 472 SUPERFAMILY SSF51971 145 401 5.0E-67 T 29-03-2018 MC49_RS01440 b35aac5302ddf5932415e6823864dc33 472 Gene3D G3DSA:1.10.1060.10 3 142 8.0E-40 T 29-03-2018 MC49_RS18855 2b760cb83830e3f613f31b6c19445a08 384 SUPERFAMILY SSF55973 233 382 3.02E-72 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MC49_RS18855 2b760cb83830e3f613f31b6c19445a08 384 Gene3D G3DSA:3.30.300.10 11 133 3.0E-44 T 29-03-2018 MC49_RS18855 2b760cb83830e3f613f31b6c19445a08 384 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 4 101 5.4E-43 T 29-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MC49_RS18855 2b760cb83830e3f613f31b6c19445a08 384 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 2 381 59.545 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MC49_RS18855 2b760cb83830e3f613f31b6c19445a08 384 Gene3D G3DSA:3.30.300.10 246 383 7.3E-51 T 29-03-2018 MC49_RS18855 2b760cb83830e3f613f31b6c19445a08 384 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 5 380 2.5E-199 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MC49_RS18855 2b760cb83830e3f613f31b6c19445a08 384 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 259 267 - T 29-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MC49_RS18855 2b760cb83830e3f613f31b6c19445a08 384 Pfam PF02772 S-adenosylmethionine synthetase, central domain 114 231 3.1E-44 T 29-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MC49_RS18855 2b760cb83830e3f613f31b6c19445a08 384 Gene3D G3DSA:3.30.300.10 134 233 1.4E-42 T 29-03-2018 MC49_RS18855 2b760cb83830e3f613f31b6c19445a08 384 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 116 126 - T 29-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MC49_RS18855 2b760cb83830e3f613f31b6c19445a08 384 SUPERFAMILY SSF55973 112 232 6.67E-51 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MC49_RS18855 2b760cb83830e3f613f31b6c19445a08 384 SUPERFAMILY SSF55973 3 109 5.89E-47 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MC49_RS18855 2b760cb83830e3f613f31b6c19445a08 384 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 233 370 4.6E-70 T 29-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MC49_RS18855 2b760cb83830e3f613f31b6c19445a08 384 PIRSF PIRSF000497 1 382 2.4E-174 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MC49_RS06955 6895639af5c096e4838d23c84cd08ec9 119 SMART SM00530 9 64 0.0062 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS06955 6895639af5c096e4838d23c84cd08ec9 119 Gene3D G3DSA:1.10.260.40 6 119 1.0E-9 T 29-03-2018 MC49_RS06955 6895639af5c096e4838d23c84cd08ec9 119 SUPERFAMILY SSF47413 3 60 2.25E-8 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS12085 669f6e938877419350f4d4602beef4a6 417 Gene3D G3DSA:3.90.1150.10 276 416 4.1E-58 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS12085 669f6e938877419350f4d4602beef4a6 417 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 417 52.764 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 MC49_RS12085 669f6e938877419350f4d4602beef4a6 417 SUPERFAMILY SSF53383 6 416 4.95E-183 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS12085 669f6e938877419350f4d4602beef4a6 417 Pfam PF00464 Serine hydroxymethyltransferase 8 386 3.5E-187 T 29-03-2018 MC49_RS12085 669f6e938877419350f4d4602beef4a6 417 PIRSF PIRSF000412 1 417 1.0E-170 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 MC49_RS12085 669f6e938877419350f4d4602beef4a6 417 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 221 237 - T 29-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 MC49_RS12085 669f6e938877419350f4d4602beef4a6 417 Gene3D G3DSA:3.40.640.10 37 275 2.3E-50 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS12175 880bd837c082e0c64accb652ae8ef1f2 392 PIRSF PIRSF006004 18 385 1.6E-143 T 29-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MC49_RS12175 880bd837c082e0c64accb652ae8ef1f2 392 Gene3D G3DSA:3.20.20.70 34 365 2.4E-39 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS12175 880bd837c082e0c64accb652ae8ef1f2 392 Pfam PF04055 Radical SAM superfamily 128 297 4.0E-16 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MC49_RS12175 880bd837c082e0c64accb652ae8ef1f2 392 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 24 377 1.7E-168 T 29-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MC49_RS12175 880bd837c082e0c64accb652ae8ef1f2 392 SUPERFAMILY SSF102114 124 347 3.79E-13 T 29-03-2018 MC49_RS12175 880bd837c082e0c64accb652ae8ef1f2 392 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 25 372 73.95 T 29-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MC49_RS14275 1367073223552aef8b9f02082aa58467 256 Pfam PF13649 Methyltransferase domain 46 143 3.8E-22 T 29-03-2018 MC49_RS14275 1367073223552aef8b9f02082aa58467 256 Gene3D G3DSA:3.40.50.150 9 250 5.6E-41 T 29-03-2018 MC49_RS14275 1367073223552aef8b9f02082aa58467 256 SUPERFAMILY SSF53335 18 247 2.43E-45 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS14415 807700834b7f35c1eb1ed9839d1aae24 538 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 463 480 - T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 MC49_RS14415 807700834b7f35c1eb1ed9839d1aae24 538 Pfam PF00367 phosphotransferase system, EIIB 454 485 8.7E-16 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 MC49_RS14415 807700834b7f35c1eb1ed9839d1aae24 538 Gene3D G3DSA:3.30.1360.60 450 524 3.4E-28 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 MC49_RS14415 807700834b7f35c1eb1ed9839d1aae24 538 TIGRFAM TIGR02004 PTS-IIBC-malX: PTS system, maltose and glucose-specific IIBC component 8 524 8.0E-260 T 29-03-2018 IPR011301 PTS system, maltose/glucose-specific IIBC component GO:0008982|GO:0009401 KEGG: 00230+2.7.1.20|KEGG: 00500+2.7.1.208|MetaCyc: PWY-6619 MC49_RS14415 807700834b7f35c1eb1ed9839d1aae24 538 SUPERFAMILY SSF55604 453 524 2.62E-21 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 MC49_RS14415 807700834b7f35c1eb1ed9839d1aae24 538 TIGRFAM TIGR00852 pts-Glc: PTS system, maltose and glucose-specific subfamily, IIC component 70 372 5.9E-88 T 29-03-2018 IPR004719 Phosphotransferase system, maltose/glucose-specific subfamily IIC component GO:0008982|GO:0009401|GO:0016021 MC49_RS14415 807700834b7f35c1eb1ed9839d1aae24 538 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 420 510 1.9E-24 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 MC49_RS14415 807700834b7f35c1eb1ed9839d1aae24 538 Pfam PF02378 Phosphotransferase system, EIIC 19 361 8.6E-86 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 MC49_RS03610 07411c5cc13439f84cdb536fdd8f176f 433 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 201 419 1.8E-46 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 MC49_RS03610 07411c5cc13439f84cdb536fdd8f176f 433 SUPERFAMILY SSF53187 346 422 4.71E-50 T 29-03-2018 MC49_RS03610 07411c5cc13439f84cdb536fdd8f176f 433 SUPERFAMILY SSF53187 199 295 4.71E-50 T 29-03-2018 MC49_RS03610 07411c5cc13439f84cdb536fdd8f176f 433 Gene3D G3DSA:3.40.630.40 196 426 4.1E-54 T 29-03-2018 MC49_RS03610 07411c5cc13439f84cdb536fdd8f176f 433 SMART SM00646 261 419 1.6E-63 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 MC49_RS03610 07411c5cc13439f84cdb536fdd8f176f 433 Pfam PF11741 AMIN domain 40 133 2.8E-10 T 29-03-2018 IPR021731 AMIN domain MC49_RS05815 03bc00e4b8095e6149b0be26171ad912 249 Gene3D G3DSA:2.40.30.10 1 96 6.1E-17 T 29-03-2018 MC49_RS05815 03bc00e4b8095e6149b0be26171ad912 249 Pfam PF00970 Oxidoreductase FAD-binding domain 10 89 1.6E-6 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 MC49_RS05815 03bc00e4b8095e6149b0be26171ad912 249 SUPERFAMILY SSF52343 103 249 7.6E-36 T 29-03-2018 MC49_RS05815 03bc00e4b8095e6149b0be26171ad912 249 Pfam PF00175 Oxidoreductase NAD-binding domain 111 223 6.1E-18 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MC49_RS05815 03bc00e4b8095e6149b0be26171ad912 249 SUPERFAMILY SSF63380 3 99 3.58E-24 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MC49_RS05815 03bc00e4b8095e6149b0be26171ad912 249 Gene3D G3DSA:3.40.50.80 97 249 4.3E-26 T 29-03-2018 MC49_RS13195 23a14dacc438d39b6ca6e0539e1d2930 147 Pfam PF00582 Universal stress protein family 1 147 3.3E-16 T 29-03-2018 IPR006016 UspA GO:0006950 MC49_RS13195 23a14dacc438d39b6ca6e0539e1d2930 147 Gene3D G3DSA:3.40.50.620 2 147 9.0E-22 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS13195 23a14dacc438d39b6ca6e0539e1d2930 147 SUPERFAMILY SSF52402 5 147 7.2E-21 T 29-03-2018 MC49_RS13195 23a14dacc438d39b6ca6e0539e1d2930 147 PRINTS PR01438 Universal stress protein signature 125 147 1.5E-7 T 29-03-2018 IPR006015 Universal stress protein A MC49_RS13195 23a14dacc438d39b6ca6e0539e1d2930 147 PRINTS PR01438 Universal stress protein signature 108 120 1.5E-7 T 29-03-2018 IPR006015 Universal stress protein A MC49_RS15510 ebd216376eb4e44178d35b7fe7fe6228 522 SMART SM00382 358 521 9.5E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS15510 ebd216376eb4e44178d35b7fe7fe6228 522 SMART SM00382 28 211 0.0017 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS15510 ebd216376eb4e44178d35b7fe7fe6228 522 Pfam PF00005 ABC transporter 351 479 3.0E-17 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS15510 ebd216376eb4e44178d35b7fe7fe6228 522 Pfam PF00005 ABC transporter 23 167 3.9E-16 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS15510 ebd216376eb4e44178d35b7fe7fe6228 522 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS15510 ebd216376eb4e44178d35b7fe7fe6228 522 SUPERFAMILY SSF52540 109 242 2.15E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS15510 ebd216376eb4e44178d35b7fe7fe6228 522 SUPERFAMILY SSF52540 6 81 2.15E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS15510 ebd216376eb4e44178d35b7fe7fe6228 522 Gene3D G3DSA:3.40.50.300 280 521 9.7E-32 T 29-03-2018 MC49_RS15510 ebd216376eb4e44178d35b7fe7fe6228 522 Gene3D G3DSA:3.40.50.300 2 273 7.7E-41 T 29-03-2018 MC49_RS15510 ebd216376eb4e44178d35b7fe7fe6228 522 SUPERFAMILY SSF52540 351 513 1.13E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS15440 9982053bd632727324754f1a834a3b4d 293 Gene3D G3DSA:2.70.98.10 6 291 2.6E-56 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 MC49_RS15440 9982053bd632727324754f1a834a3b4d 293 SUPERFAMILY SSF74650 8 275 2.51E-69 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 MC49_RS15440 9982053bd632727324754f1a834a3b4d 293 PIRSF PIRSF016020 9 286 1.8E-55 T 29-03-2018 IPR025532 Glucose-6-phosphate 1-epimerase KEGG: 00010+5.1.3.15 MC49_RS15440 9982053bd632727324754f1a834a3b4d 293 Pfam PF01263 Aldose 1-epimerase 28 271 1.0E-45 T 29-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 MC49_RS19010 95261ecc301035316211e34c9def7e8f 333 SMART SM00354 8 78 4.7E-19 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MC49_RS19010 95261ecc301035316211e34c9def7e8f 333 Gene3D G3DSA:3.40.50.2300 63 186 3.1E-31 T 29-03-2018 MC49_RS19010 95261ecc301035316211e34c9def7e8f 333 Pfam PF00356 Bacterial regulatory proteins, lacI family 10 55 5.1E-9 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MC49_RS19010 95261ecc301035316211e34c9def7e8f 333 Pfam PF13407 Periplasmic binding protein domain 69 281 8.5E-21 T 29-03-2018 IPR025997 Periplasmic binding protein MC49_RS19010 95261ecc301035316211e34c9def7e8f 333 SUPERFAMILY SSF53822 66 326 4.91E-46 T 29-03-2018 IPR028082 Periplasmic binding protein-like I MC49_RS19010 95261ecc301035316211e34c9def7e8f 333 Gene3D G3DSA:3.40.50.2300 187 331 1.4E-22 T 29-03-2018 MC49_RS19010 95261ecc301035316211e34c9def7e8f 333 SUPERFAMILY SSF47413 7 66 2.06E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS19010 95261ecc301035316211e34c9def7e8f 333 Gene3D G3DSA:1.10.260.40 9 62 1.3E-17 T 29-03-2018 MC49_RS12685 726f40e5fb75b781e681a7351002eb1b 129 Gene3D G3DSA:1.20.58.380 13 97 2.6E-17 T 29-03-2018 MC49_RS12685 726f40e5fb75b781e681a7351002eb1b 129 Pfam PF05400 Flagellar protein FliT 30 113 3.3E-16 T 29-03-2018 IPR008622 Flagellar protein FliT MC49_RS16205 9695b442b3d28accaf75fa9ba7d7cf18 443 Pfam PF14378 PAP2 superfamily 125 203 2.7E-7 T 29-03-2018 IPR026841 Inositolphosphotransferase Aur1/Ipt1 MC49_RS16205 9695b442b3d28accaf75fa9ba7d7cf18 443 SUPERFAMILY SSF52799 288 441 1.36E-18 T 29-03-2018 IPR029021 Protein-tyrosine phosphatase-like MC49_RS16205 9695b442b3d28accaf75fa9ba7d7cf18 443 Pfam PF00782 Dual specificity phosphatase, catalytic domain 373 435 1.2E-11 T 29-03-2018 IPR000340 Dual specificity phosphatase, catalytic domain GO:0008138|GO:0016311 MC49_RS16205 9695b442b3d28accaf75fa9ba7d7cf18 443 Gene3D G3DSA:1.20.144.10 4 224 0.0012 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MC49_RS16205 9695b442b3d28accaf75fa9ba7d7cf18 443 SMART SM00195 306 437 2.1E-4 T 29-03-2018 IPR020422 Dual specificity protein phosphatase domain GO:0006470|GO:0008138 MC49_RS16205 9695b442b3d28accaf75fa9ba7d7cf18 443 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 381 391 - T 29-03-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 MC49_RS16205 9695b442b3d28accaf75fa9ba7d7cf18 443 Gene3D G3DSA:3.90.190.10 298 443 6.0E-13 T 29-03-2018 IPR029021 Protein-tyrosine phosphatase-like MC49_RS07995 4c2dd2bcf60fbc3273b8e50e9a363ac4 253 SUPERFAMILY SSF55120 14 251 6.4E-63 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS07995 4c2dd2bcf60fbc3273b8e50e9a363ac4 253 Pfam PF00849 RNA pseudouridylate synthase 25 184 8.3E-32 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS07995 4c2dd2bcf60fbc3273b8e50e9a363ac4 253 Gene3D G3DSA:3.30.2350.10 16 251 2.9E-61 T 29-03-2018 MC49_RS07995 4c2dd2bcf60fbc3273b8e50e9a363ac4 253 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 65 79 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS08350 31818c54e34f7c2acc818b19efe34b6a 303 SUPERFAMILY SSF53850 95 297 9.41E-29 T 29-03-2018 MC49_RS08350 31818c54e34f7c2acc818b19efe34b6a 303 Gene3D G3DSA:3.40.190.10 96 177 1.4E-10 T 29-03-2018 MC49_RS08350 31818c54e34f7c2acc818b19efe34b6a 303 Pfam PF03466 LysR substrate binding domain 94 294 4.4E-30 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS08350 31818c54e34f7c2acc818b19efe34b6a 303 Gene3D G3DSA:1.10.10.10 4 88 8.4E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS08350 31818c54e34f7c2acc818b19efe34b6a 303 Gene3D G3DSA:3.40.190.10 178 266 2.6E-18 T 29-03-2018 MC49_RS08350 31818c54e34f7c2acc818b19efe34b6a 303 SUPERFAMILY SSF46785 4 83 9.01E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS08350 31818c54e34f7c2acc818b19efe34b6a 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 67 3.1E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS08350 31818c54e34f7c2acc818b19efe34b6a 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 6.3E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS08350 31818c54e34f7c2acc818b19efe34b6a 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 6.3E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS08350 31818c54e34f7c2acc818b19efe34b6a 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 6.3E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS10315 3fb45ac8c6c030d7ac834833a91ee4de 184 Gene3D G3DSA:1.20.1380.10 78 180 9.1E-40 T 29-03-2018 IPR026577 Replication modulator SeqA, C-terminal DNA-binding domain GO:0003677 MC49_RS10315 3fb45ac8c6c030d7ac834833a91ee4de 184 SUPERFAMILY SSF82808 69 183 6.02E-47 T 29-03-2018 IPR026577 Replication modulator SeqA, C-terminal DNA-binding domain GO:0003677 MC49_RS10315 3fb45ac8c6c030d7ac834833a91ee4de 184 Hamap MF_00908 Negative modulator of initiation of replication [seqA]. 1 184 41.253 T 29-03-2018 IPR005621 Negative modulator of initiation of replication SeqA GO:0003677|GO:0032297 MC49_RS10315 3fb45ac8c6c030d7ac834833a91ee4de 184 Gene3D G3DSA:1.10.1220.10 1 37 3.3E-24 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 MC49_RS10315 3fb45ac8c6c030d7ac834833a91ee4de 184 PIRSF PIRSF019401 1 184 9.8E-51 T 29-03-2018 IPR005621 Negative modulator of initiation of replication SeqA GO:0003677|GO:0032297 MC49_RS10315 3fb45ac8c6c030d7ac834833a91ee4de 184 Pfam PF17206 SeqA protein N-terminal domain 1 35 5.3E-24 T 29-03-2018 IPR033761 Negative modulator of initiation of replication SeqA, N-terminal MC49_RS10315 3fb45ac8c6c030d7ac834833a91ee4de 184 Pfam PF03925 SeqA protein C-terminal domain 74 182 1.2E-47 T 29-03-2018 IPR026577 Replication modulator SeqA, C-terminal DNA-binding domain GO:0003677 MC49_RS10315 3fb45ac8c6c030d7ac834833a91ee4de 184 SUPERFAMILY SSF47598 1 35 2.45E-13 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 MC49_RS10820 5dd6c534f1c591d3ff57fc0ee9e62dc4 462 TIGRFAM TIGR00771 DcuC: transporter, anaerobic C4-dicarboxylate uptake C (DcuC) family 58 448 2.3E-162 T 29-03-2018 IPR004669 C4-dicarboxylate anaerobic carrier GO:0015556|GO:0015740|GO:0016021 MC49_RS10820 5dd6c534f1c591d3ff57fc0ee9e62dc4 462 Pfam PF03606 C4-dicarboxylate anaerobic carrier 2 457 9.5E-127 T 29-03-2018 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 MC49_RS07985 bd6e7f6ef9413df6649626224c590209 183 Hamap MF_01104 Protein Syd [syd]. 3 181 33.995 T 29-03-2018 IPR009948 Syd GO:0009898 MC49_RS07985 bd6e7f6ef9413df6649626224c590209 183 Pfam PF07348 Syd protein (SUKH-2) 7 178 2.2E-68 T 29-03-2018 IPR009948 Syd GO:0009898 MC49_RS00730 95fbd0bba45742c3e14701ea763b399b 622 Pfam PF13145 PPIC-type PPIASE domain 248 370 6.7E-20 T 29-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 MC49_RS00730 95fbd0bba45742c3e14701ea763b399b 622 Gene3D G3DSA:3.10.50.40 188 377 1.3E-22 T 29-03-2018 MC49_RS00730 95fbd0bba45742c3e14701ea763b399b 622 Gene3D G3DSA:3.10.50.40 378 497 5.4E-6 T 29-03-2018 MC49_RS00730 95fbd0bba45742c3e14701ea763b399b 622 SUPERFAMILY SSF54534 226 354 2.49E-18 T 29-03-2018 MC49_RS00730 95fbd0bba45742c3e14701ea763b399b 622 SUPERFAMILY SSF109998 38 171 4.45E-31 T 29-03-2018 IPR027304 Trigger factor/SurA domain MC49_RS00730 95fbd0bba45742c3e14701ea763b399b 622 SUPERFAMILY SSF109998 205 238 4.45E-31 T 29-03-2018 IPR027304 Trigger factor/SurA domain MC49_RS00730 95fbd0bba45742c3e14701ea763b399b 622 Pfam PF13624 SurA N-terminal domain 1 164 6.2E-48 T 29-03-2018 MC49_RS00730 95fbd0bba45742c3e14701ea763b399b 622 Gene3D G3DSA:1.10.4030.10 36 171 1.5E-23 T 29-03-2018 MC49_RS12335 d5992025b45550608e6415d137444f29 203 Pfam PF00196 Bacterial regulatory proteins, luxR family 135 188 1.8E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS12335 d5992025b45550608e6415d137444f29 203 Gene3D G3DSA:3.40.50.2300 2 107 2.4E-24 T 29-03-2018 MC49_RS12335 d5992025b45550608e6415d137444f29 203 SMART SM00448 2 113 6.1E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS12335 d5992025b45550608e6415d137444f29 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 136 150 9.2E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS12335 d5992025b45550608e6415d137444f29 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 178 9.2E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS12335 d5992025b45550608e6415d137444f29 203 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 166 9.2E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS12335 d5992025b45550608e6415d137444f29 203 SMART SM00421 133 190 3.8E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS12335 d5992025b45550608e6415d137444f29 203 Pfam PF00072 Response regulator receiver domain 4 113 2.5E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS12335 d5992025b45550608e6415d137444f29 203 Gene3D G3DSA:1.10.10.10 108 193 1.0E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS12335 d5992025b45550608e6415d137444f29 203 SUPERFAMILY SSF52172 4 147 1.07E-29 T 29-03-2018 IPR011006 CheY-like superfamily MC49_RS12335 d5992025b45550608e6415d137444f29 203 SUPERFAMILY SSF46894 126 190 2.52E-16 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MC49_RS07780 6a36020437de5e42f354b935574724e4 277 SUPERFAMILY SSF56300 1 259 1.42E-55 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like MC49_RS07780 6a36020437de5e42f354b935574724e4 277 Gene3D G3DSA:3.60.21.10 1 276 1.0E-45 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like MC49_RS07780 6a36020437de5e42f354b935574724e4 277 Pfam PF00149 Calcineurin-like phosphoesterase 4 127 2.0E-11 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MC49_RS07780 6a36020437de5e42f354b935574724e4 277 TIGRFAM TIGR00668 apaH: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) 1 273 7.0E-140 T 29-03-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 MC49_RS07780 6a36020437de5e42f354b935574724e4 277 PIRSF PIRSF000903 1 274 2.4E-117 T 29-03-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 MC49_RS07780 6a36020437de5e42f354b935574724e4 277 Hamap MF_00199 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical [apaH]. 1 271 49.882 T 29-03-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 MC49_RS14315 d78275e574e873b0d33ee8b95a72cccf 504 Gene3D G3DSA:2.20.28.10 450 501 7.3E-17 T 29-03-2018 MC49_RS14315 d78275e574e873b0d33ee8b95a72cccf 504 Hamap MF_01312 Anaerobic nitric oxide reductase flavorubredoxin [norV]. 1 500 84.916 T 29-03-2018 IPR023957 Anaerobic nitric oxide reductase flavorubredoxin GO:0005506|GO:0016966 MC49_RS14315 d78275e574e873b0d33ee8b95a72cccf 504 PRINTS PR00163 Rubredoxin signature 480 496 1.0E-5 T 29-03-2018 IPR024935 Rubredoxin domain GO:0005506 MC49_RS14315 d78275e574e873b0d33ee8b95a72cccf 504 PRINTS PR00163 Rubredoxin signature 450 466 1.0E-5 T 29-03-2018 IPR024935 Rubredoxin domain GO:0005506 MC49_RS14315 d78275e574e873b0d33ee8b95a72cccf 504 Pfam PF00301 Rubredoxin 451 496 2.7E-17 T 29-03-2018 IPR024935 Rubredoxin domain GO:0005506 MC49_RS14315 d78275e574e873b0d33ee8b95a72cccf 504 SUPERFAMILY SSF57802 450 500 3.2E-16 T 29-03-2018 MC49_RS14315 d78275e574e873b0d33ee8b95a72cccf 504 Pfam PF00753 Metallo-beta-lactamase superfamily 35 174 4.7E-11 T 29-03-2018 IPR001279 Metallo-beta-lactamase MC49_RS14315 d78275e574e873b0d33ee8b95a72cccf 504 SUPERFAMILY SSF52218 251 396 8.71E-35 T 29-03-2018 IPR029039 Flavoprotein-like domain MC49_RS14315 d78275e574e873b0d33ee8b95a72cccf 504 Gene3D G3DSA:3.60.15.10 1 247 3.4E-40 T 29-03-2018 IPR001279 Metallo-beta-lactamase MC49_RS14315 d78275e574e873b0d33ee8b95a72cccf 504 SUPERFAMILY SSF56281 8 285 6.81E-51 T 29-03-2018 IPR001279 Metallo-beta-lactamase MC49_RS14315 d78275e574e873b0d33ee8b95a72cccf 504 Gene3D G3DSA:3.40.50.360 253 395 9.6E-21 T 29-03-2018 IPR029039 Flavoprotein-like domain MC49_RS14315 d78275e574e873b0d33ee8b95a72cccf 504 SMART SM00849 34 210 4.8E-29 T 29-03-2018 IPR001279 Metallo-beta-lactamase MC49_RS14315 d78275e574e873b0d33ee8b95a72cccf 504 Pfam PF00258 Flavodoxin 256 387 2.1E-12 T 29-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 MC49_RS00970 5562cf2ae20b368aaa7fa5fd4fe3bc7b 339 Gene3D G3DSA:3.30.1330.10 4 159 2.1E-22 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MC49_RS00970 5562cf2ae20b368aaa7fa5fd4fe3bc7b 339 Pfam PF00586 AIR synthase related protein, N-terminal domain 52 156 1.2E-14 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MC49_RS00970 5562cf2ae20b368aaa7fa5fd4fe3bc7b 339 PIRSF PIRSF005644 3 339 1.3E-116 T 29-03-2018 IPR011854 Hydrogenase expression/formation protein HypE MC49_RS00970 5562cf2ae20b368aaa7fa5fd4fe3bc7b 339 SUPERFAMILY SSF56042 166 334 3.44E-40 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MC49_RS00970 5562cf2ae20b368aaa7fa5fd4fe3bc7b 339 Gene3D G3DSA:3.90.650.10 164 327 5.4E-35 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MC49_RS00970 5562cf2ae20b368aaa7fa5fd4fe3bc7b 339 Pfam PF02769 AIR synthase related protein, C-terminal domain 168 318 4.2E-26 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MC49_RS00970 5562cf2ae20b368aaa7fa5fd4fe3bc7b 339 SUPERFAMILY SSF55326 5 159 4.01E-31 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MC49_RS00970 5562cf2ae20b368aaa7fa5fd4fe3bc7b 339 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 7 339 4.3E-132 T 29-03-2018 IPR011854 Hydrogenase expression/formation protein HypE MC49_RS17775 275c7e1a9188026f068d84cb65f0a0a7 283 Pfam PF13730 Helix-turn-helix domain 24 70 1.9E-7 T 29-03-2018 MC49_RS17775 275c7e1a9188026f068d84cb65f0a0a7 283 Gene3D G3DSA:1.10.10.10 20 103 6.2E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS11805 02a1713512f36b9afa778cf19ba33053 155 PIRSF PIRSF004923 1 150 1.0E-36 T 29-03-2018 IPR026268 Protein RseC MC49_RS11805 02a1713512f36b9afa778cf19ba33053 155 Pfam PF04246 Positive regulator of sigma(E), RseC/MucC 8 140 9.8E-33 T 29-03-2018 IPR007359 Positive regulator of sigma(E), RseC/MucC MC49_RS15295 e28f54e2d3c6afa06ec9ab2de7dfa0b9 543 Gene3D G3DSA:3.10.105.10 311 511 3.1E-52 T 29-03-2018 MC49_RS15295 e28f54e2d3c6afa06ec9ab2de7dfa0b9 543 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 81 462 4.9E-83 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain MC49_RS15295 e28f54e2d3c6afa06ec9ab2de7dfa0b9 543 SUPERFAMILY SSF53850 35 526 2.35E-139 T 29-03-2018 MC49_RS15295 e28f54e2d3c6afa06ec9ab2de7dfa0b9 543 Gene3D G3DSA:3.90.76.10 62 174 8.7E-38 T 29-03-2018 MC49_RS15295 e28f54e2d3c6afa06ec9ab2de7dfa0b9 543 PIRSF PIRSF002741 1 542 8.4E-108 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MC49_RS15295 e28f54e2d3c6afa06ec9ab2de7dfa0b9 543 Gene3D G3DSA:3.40.190.10 175 310 5.4E-34 T 29-03-2018 MC49_RS05295 1c0e8a3ab4b2ca7a6eae465baff322d7 455 Gene3D G3DSA:3.40.640.10 59 322 3.5E-37 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS05295 1c0e8a3ab4b2ca7a6eae465baff322d7 455 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 44 374 1.6E-81 T 29-03-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 MC49_RS05295 1c0e8a3ab4b2ca7a6eae465baff322d7 455 Gene3D G3DSA:3.90.1150.10 323 439 5.9E-20 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS05295 1c0e8a3ab4b2ca7a6eae465baff322d7 455 TIGRFAM TIGR01788 Glu-decarb-GAD: glutamate decarboxylase 18 437 1.1E-189 T 29-03-2018 IPR010107 Glutamate decarboxylase GO:0004351|GO:0006536|GO:0030170 KEGG: 00250+4.1.1.15|KEGG: 00410+4.1.1.15|KEGG: 00430+4.1.1.15|KEGG: 00650+4.1.1.15|MetaCyc: PWY-4321 MC49_RS05295 1c0e8a3ab4b2ca7a6eae465baff322d7 455 SUPERFAMILY SSF53383 17 441 6.52E-136 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS03880 72fbc6987f449c2ca36e30dc70fbabfc 298 SUPERFAMILY SSF46785 1 111 1.41E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS03880 72fbc6987f449c2ca36e30dc70fbabfc 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 8.3E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS03880 72fbc6987f449c2ca36e30dc70fbabfc 298 Gene3D G3DSA:1.10.10.10 1 79 7.2E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS03880 72fbc6987f449c2ca36e30dc70fbabfc 298 SUPERFAMILY SSF53850 89 296 5.94E-35 T 29-03-2018 MC49_RS03880 72fbc6987f449c2ca36e30dc70fbabfc 298 Gene3D G3DSA:3.40.190.10 80 185 1.3E-19 T 29-03-2018 MC49_RS03880 72fbc6987f449c2ca36e30dc70fbabfc 298 Pfam PF03466 LysR substrate binding domain 89 295 6.5E-39 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS03880 72fbc6987f449c2ca36e30dc70fbabfc 298 Gene3D G3DSA:3.40.190.10 186 264 3.6E-10 T 29-03-2018 MC49_RS14695 6ccaec174f4c81c91463c9435479c9ec 196 Pfam PF14378 PAP2 superfamily 39 189 8.3E-18 T 29-03-2018 IPR026841 Inositolphosphotransferase Aur1/Ipt1 MC49_RS14695 6ccaec174f4c81c91463c9435479c9ec 196 SUPERFAMILY SSF48317 7 191 5.23E-9 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MC49_RS14695 6ccaec174f4c81c91463c9435479c9ec 196 Gene3D G3DSA:1.20.144.10 10 193 1.8E-9 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MC49_RS06740 b036671a494d90e46aa36ff6a4364d37 72 Gene3D G3DSA:1.10.260.40 1 71 1.0E-17 T 29-03-2018 MC49_RS06740 b036671a494d90e46aa36ff6a4364d37 72 SUPERFAMILY SSF47413 3 54 5.38E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS06740 b036671a494d90e46aa36ff6a4364d37 72 Pfam PF01381 Helix-turn-helix 5 53 7.9E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS06740 b036671a494d90e46aa36ff6a4364d37 72 SMART SM00530 3 58 4.6E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS12115 4ebf1c9a628220eacf6a6d60d0a726dc 128 TIGRFAM TIGR01999 iscU: FeS cluster assembly scaffold IscU 3 125 4.2E-70 T 29-03-2018 IPR011339 ISC system FeS cluster assembly, IscU scaffold GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 MC49_RS12115 4ebf1c9a628220eacf6a6d60d0a726dc 128 Pfam PF01592 NifU-like N terminal domain 2 125 6.8E-57 T 29-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 MC49_RS12115 4ebf1c9a628220eacf6a6d60d0a726dc 128 SUPERFAMILY SSF82649 1 125 2.12E-49 T 29-03-2018 MC49_RS12115 4ebf1c9a628220eacf6a6d60d0a726dc 128 Gene3D G3DSA:3.90.1010.10 1 128 4.7E-53 T 29-03-2018 MC49_RS10465 8068c392edf10549fea5d9b2101d90d5 259 Gene3D G3DSA:1.20.5.50 33 110 2.5E-5 T 29-03-2018 MC49_RS10465 8068c392edf10549fea5d9b2101d90d5 259 Hamap MF_02066 Cell division coordinator CpoB [cpoB]. 6 259 19.186 T 29-03-2018 IPR034706 Cell division coordinator CpoB GO:0051301 MC49_RS10465 8068c392edf10549fea5d9b2101d90d5 259 TIGRFAM TIGR02795 tol_pal_ybgF: tol-pal system protein YbgF 139 256 3.0E-40 T 29-03-2018 IPR014162 Cell division coordinator CpoB, C-terminal MC49_RS10465 8068c392edf10549fea5d9b2101d90d5 259 SUPERFAMILY SSF48452 141 250 3.8E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MC49_RS10465 8068c392edf10549fea5d9b2101d90d5 259 Pfam PF13174 Tetratricopeptide repeat 214 246 6.1E-7 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MC49_RS10465 8068c392edf10549fea5d9b2101d90d5 259 Gene3D G3DSA:1.25.40.10 140 259 2.5E-17 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MC49_RS10465 8068c392edf10549fea5d9b2101d90d5 259 Pfam PF13432 Tetratricopeptide repeat 149 209 4.2E-8 T 29-03-2018 MC49_RS10465 8068c392edf10549fea5d9b2101d90d5 259 Pfam PF16331 TolA binding protein trimerisation 37 109 3.6E-23 T 29-03-2018 IPR032519 YbgF, trimerisation domain GO:0070206 MC49_RS00935 0f3fa0e3c58dd7b3382cb970dcb348d6 200 Pfam PF00881 Nitroreductase family 9 178 2.8E-17 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MC49_RS00935 0f3fa0e3c58dd7b3382cb970dcb348d6 200 Gene3D G3DSA:3.40.109.10 3 199 1.1E-25 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MC49_RS00935 0f3fa0e3c58dd7b3382cb970dcb348d6 200 SUPERFAMILY SSF55469 3 199 3.01E-75 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MC49_RS10595 c9f364e2dd8ab9123de4f75de43c06af 670 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 5 662 0.0 T 29-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 MC49_RS10595 c9f364e2dd8ab9123de4f75de43c06af 670 Hamap MF_00204 UvrABC system protein B [uvrB]. 3 665 44.187 T 29-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 MC49_RS10595 c9f364e2dd8ab9123de4f75de43c06af 670 Gene3D G3DSA:3.40.50.300 10 414 4.6E-33 T 29-03-2018 MC49_RS10595 c9f364e2dd8ab9123de4f75de43c06af 670 Pfam PF12344 Ultra-violet resistance protein B 552 593 4.3E-21 T 29-03-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain MC49_RS10595 c9f364e2dd8ab9123de4f75de43c06af 670 SMART SM00487 9 426 1.6E-28 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MC49_RS10595 c9f364e2dd8ab9123de4f75de43c06af 670 Gene3D G3DSA:3.40.50.300 415 589 6.9E-32 T 29-03-2018 MC49_RS10595 c9f364e2dd8ab9123de4f75de43c06af 670 SUPERFAMILY SSF46600 619 666 1.1E-11 T 29-03-2018 IPR001943 UVR domain GO:0005515 MC49_RS10595 c9f364e2dd8ab9123de4f75de43c06af 670 Pfam PF00271 Helicase conserved C-terminal domain 438 544 1.6E-17 T 29-03-2018 IPR001650 Helicase, C-terminal MC49_RS10595 c9f364e2dd8ab9123de4f75de43c06af 670 Pfam PF04851 Type III restriction enzyme, res subunit 13 92 2.0E-8 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MC49_RS10595 c9f364e2dd8ab9123de4f75de43c06af 670 Gene3D G3DSA:4.10.860.10 608 670 4.6E-17 T 29-03-2018 IPR001943 UVR domain GO:0005515 MC49_RS10595 c9f364e2dd8ab9123de4f75de43c06af 670 SMART SM00490 460 546 8.9E-20 T 29-03-2018 IPR001650 Helicase, C-terminal MC49_RS10595 c9f364e2dd8ab9123de4f75de43c06af 670 SUPERFAMILY SSF52540 459 584 1.97E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS10595 c9f364e2dd8ab9123de4f75de43c06af 670 SUPERFAMILY SSF52540 37 82 1.97E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS10595 c9f364e2dd8ab9123de4f75de43c06af 670 Pfam PF02151 UvrB/uvrC motif 631 665 1.0E-7 T 29-03-2018 IPR001943 UVR domain GO:0005515 MC49_RS10595 c9f364e2dd8ab9123de4f75de43c06af 670 SUPERFAMILY SSF52540 3 415 6.39E-138 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS10175 108a965ac3dbb25748a5c3ca09db2ba0 300 SMART SM00062 39 271 2.5E-66 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MC49_RS10175 108a965ac3dbb25748a5c3ca09db2ba0 300 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 40 269 2.9E-46 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MC49_RS10175 108a965ac3dbb25748a5c3ca09db2ba0 300 SUPERFAMILY SSF53850 3 272 5.05E-62 T 29-03-2018 MC49_RS10175 108a965ac3dbb25748a5c3ca09db2ba0 300 Gene3D G3DSA:3.40.190.10 5 167 1.0E-29 T 29-03-2018 MC49_RS10175 108a965ac3dbb25748a5c3ca09db2ba0 300 Gene3D G3DSA:3.40.190.10 168 300 1.1E-17 T 29-03-2018 MC49_RS01695 e0f09eab5e1ee39a20a1fd35f290fa67 449 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 445 3.2E-246 T 29-03-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 MC49_RS01695 e0f09eab5e1ee39a20a1fd35f290fa67 449 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 9.7E-45 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MC49_RS01695 e0f09eab5e1ee39a20a1fd35f290fa67 449 Gene3D G3DSA:3.30.470.20 210 444 1.1E-95 T 29-03-2018 MC49_RS01695 e0f09eab5e1ee39a20a1fd35f290fa67 449 Gene3D G3DSA:3.30.1490.20 124 209 1.3E-19 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MC49_RS01695 e0f09eab5e1ee39a20a1fd35f290fa67 449 Gene3D G3DSA:3.40.50.20 1 123 3.1E-51 T 29-03-2018 MC49_RS01695 e0f09eab5e1ee39a20a1fd35f290fa67 449 Pfam PF02785 Biotin carboxylase C-terminal domain 336 441 5.3E-39 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MC49_RS01695 e0f09eab5e1ee39a20a1fd35f290fa67 449 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 322 1.1E-81 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MC49_RS01695 e0f09eab5e1ee39a20a1fd35f290fa67 449 SUPERFAMILY SSF52440 1 113 4.46E-47 T 29-03-2018 IPR016185 Pre-ATP-grasp domain MC49_RS01695 e0f09eab5e1ee39a20a1fd35f290fa67 449 SUPERFAMILY SSF56059 83 348 6.57E-67 T 29-03-2018 MC49_RS01695 e0f09eab5e1ee39a20a1fd35f290fa67 449 SUPERFAMILY SSF51246 331 444 4.13E-44 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MC49_RS01695 e0f09eab5e1ee39a20a1fd35f290fa67 449 SMART SM00878 336 441 1.2E-66 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MC49_RS01695 e0f09eab5e1ee39a20a1fd35f290fa67 449 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MC49_RS01695 e0f09eab5e1ee39a20a1fd35f290fa67 449 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 154 168 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MC49_RS08445 1da4cd6216b202875df1aa6b35a531e4 209 Pfam PF02570 Precorrin-8X methylmutase 9 204 4.8E-68 T 29-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 MC49_RS08445 1da4cd6216b202875df1aa6b35a531e4 209 SUPERFAMILY SSF63965 9 206 2.22E-65 T 29-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 MC49_RS08445 1da4cd6216b202875df1aa6b35a531e4 209 Gene3D G3DSA:3.40.50.10230 3 209 2.4E-75 T 29-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 MC49_RS13665 e42e33cf9311718c9937a242570e629f 77 Pfam PF06440 DNA polymerase III, theta subunit 2 71 5.8E-38 T 29-03-2018 IPR009052 DNA polymerase III-theta, bacterial GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS13665 e42e33cf9311718c9937a242570e629f 77 Gene3D G3DSA:1.20.58.250 3 64 8.3E-30 T 29-03-2018 IPR009052 DNA polymerase III-theta, bacterial GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS13665 e42e33cf9311718c9937a242570e629f 77 ProDom PD057609 DNA POLYMERASE THETA SUBUNIT TRANSFERASE III NUCLEOTIDYLTRANSFERASE III DNA-DIRECTED REPLICATION 4 76 9.0E-25 T 29-03-2018 IPR009052 DNA polymerase III-theta, bacterial GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS13665 e42e33cf9311718c9937a242570e629f 77 SUPERFAMILY SSF46575 2 75 3.66E-32 T 29-03-2018 MC49_RS06390 ca6f15a1950e2150ff32ed6854846e6d 394 Gene3D G3DSA:3.40.50.300 2 74 4.0E-11 T 29-03-2018 MC49_RS06390 ca6f15a1950e2150ff32ed6854846e6d 394 PRINTS PR00315 GTP-binding elongation factor signature 58 66 2.9E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS06390 ca6f15a1950e2150ff32ed6854846e6d 394 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.9E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS06390 ca6f15a1950e2150ff32ed6854846e6d 394 PRINTS PR00315 GTP-binding elongation factor signature 131 140 2.9E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS06390 ca6f15a1950e2150ff32ed6854846e6d 394 PRINTS PR00315 GTP-binding elongation factor signature 94 105 2.9E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS06390 ca6f15a1950e2150ff32ed6854846e6d 394 PRINTS PR00315 GTP-binding elongation factor signature 78 88 2.9E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS06390 ca6f15a1950e2150ff32ed6854846e6d 394 Pfam PF03143 Elongation factor Tu C-terminal domain 298 392 8.2E-34 T 29-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal MC49_RS06390 ca6f15a1950e2150ff32ed6854846e6d 394 Gene3D G3DSA:2.40.30.10 206 299 1.3E-32 T 29-03-2018 MC49_RS06390 ca6f15a1950e2150ff32ed6854846e6d 394 Gene3D G3DSA:2.40.30.10 300 393 8.2E-33 T 29-03-2018 MC49_RS06390 ca6f15a1950e2150ff32ed6854846e6d 394 Pfam PF00009 Elongation factor Tu GTP binding domain 10 201 7.6E-58 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS06390 ca6f15a1950e2150ff32ed6854846e6d 394 Pfam PF03144 Elongation factor Tu domain 2 225 293 1.9E-17 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MC49_RS06390 ca6f15a1950e2150ff32ed6854846e6d 394 SUPERFAMILY SSF52540 6 219 2.41E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS06390 ca6f15a1950e2150ff32ed6854846e6d 394 Gene3D G3DSA:3.40.50.300 75 203 1.9E-30 T 29-03-2018 MC49_RS06390 ca6f15a1950e2150ff32ed6854846e6d 394 SUPERFAMILY SSF50465 298 393 3.45E-36 T 29-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal MC49_RS06390 ca6f15a1950e2150ff32ed6854846e6d 394 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 148 2.0E-14 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MC49_RS06390 ca6f15a1950e2150ff32ed6854846e6d 394 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 2 393 4.4E-238 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MC49_RS06390 ca6f15a1950e2150ff32ed6854846e6d 394 SUPERFAMILY SSF50447 205 301 3.53E-30 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain MC49_RS06390 ca6f15a1950e2150ff32ed6854846e6d 394 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site MC49_RS06390 ca6f15a1950e2150ff32ed6854846e6d 394 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 394 60.842 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MC49_RS05105 9228c7abf8b19736c2c2a3616d4ac32a 508 Pfam PF07728 AAA domain (dynein-related subfamily) 37 167 5.1E-23 T 29-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 MC49_RS05105 9228c7abf8b19736c2c2a3616d4ac32a 508 SMART SM00382 34 182 3.1E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS05105 9228c7abf8b19736c2c2a3616d4ac32a 508 Gene3D G3DSA:3.40.50.300 2 234 3.3E-18 T 29-03-2018 MC49_RS05105 9228c7abf8b19736c2c2a3616d4ac32a 508 Pfam PF12592 Protein of unknown function (DUF3763) 448 501 3.5E-19 T 29-03-2018 IPR022547 ATPase, RavA, C-terminal GO:0016820 MC49_RS05105 9228c7abf8b19736c2c2a3616d4ac32a 508 SUPERFAMILY SSF52540 9 280 6.57E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS01855 5124ea1deb5ed450a3ae7de42a7713fe 221 Gene3D G3DSA:3.40.50.300 1 219 9.7E-63 T 29-03-2018 MC49_RS01855 5124ea1deb5ed450a3ae7de42a7713fe 221 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 214 1.8E-93 T 29-03-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 MC49_RS01855 5124ea1deb5ed450a3ae7de42a7713fe 221 SMART SM00382 27 214 3.4E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS01855 5124ea1deb5ed450a3ae7de42a7713fe 221 Pfam PF00005 ABC transporter 18 165 2.2E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS01855 5124ea1deb5ed450a3ae7de42a7713fe 221 SUPERFAMILY SSF52540 1 216 6.41E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS01855 5124ea1deb5ed450a3ae7de42a7713fe 221 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS07555 e4b403a3f26dc67dd80c8aac087427a6 194 SUPERFAMILY SSF53218 5 189 7.59E-48 T 29-03-2018 IPR001453 MoaB/Mog domain MC49_RS07555 e4b403a3f26dc67dd80c8aac087427a6 194 Pfam PF00994 Probable molybdopterin binding domain 9 148 3.3E-28 T 29-03-2018 IPR001453 MoaB/Mog domain MC49_RS07555 e4b403a3f26dc67dd80c8aac087427a6 194 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 70 83 - T 29-03-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 MC49_RS07555 e4b403a3f26dc67dd80c8aac087427a6 194 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 5 148 7.1E-40 T 29-03-2018 IPR001453 MoaB/Mog domain MC49_RS07555 e4b403a3f26dc67dd80c8aac087427a6 194 SMART SM00852 8 154 1.8E-22 T 29-03-2018 IPR001453 MoaB/Mog domain MC49_RS07555 e4b403a3f26dc67dd80c8aac087427a6 194 Gene3D G3DSA:3.40.980.10 1 189 1.2E-39 T 29-03-2018 IPR001453 MoaB/Mog domain MC49_RS08745 5e4f2e21c2ed308bf036f048ee3b75f1 276 Gene3D G3DSA:3.40.50.1820 1 275 8.3E-44 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS08745 5e4f2e21c2ed308bf036f048ee3b75f1 276 Pfam PF00756 Putative esterase 21 267 1.6E-64 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 MC49_RS08745 5e4f2e21c2ed308bf036f048ee3b75f1 276 TIGRFAM TIGR02821 fghA_ester_D: S-formylglutathione hydrolase 3 274 3.9E-126 T 29-03-2018 IPR014186 S-formylglutathione hydrolase GO:0018738|GO:0046294 KEGG: 00680+3.1.2.12|MetaCyc: PWY-1801|Reactome: R-HSA-156590 MC49_RS08745 5e4f2e21c2ed308bf036f048ee3b75f1 276 SUPERFAMILY SSF53474 1 275 5.71E-85 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS04545 950110f82d20fafed486b7e3d141b0b2 473 Pfam PF02614 Glucuronate isomerase 1 467 8.6E-224 T 29-03-2018 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 MC49_RS04545 950110f82d20fafed486b7e3d141b0b2 473 Hamap MF_00675 Uronate isomerase [uxaC]. 2 469 50.382 T 29-03-2018 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 MC49_RS04545 950110f82d20fafed486b7e3d141b0b2 473 SUPERFAMILY SSF51556 2 467 1.5E-182 T 29-03-2018 IPR032466 Metal-dependent hydrolase MC49_RS04545 950110f82d20fafed486b7e3d141b0b2 473 Gene3D G3DSA:3.20.20.140 91 468 1.3E-155 T 29-03-2018 MC49_RS04545 950110f82d20fafed486b7e3d141b0b2 473 Gene3D G3DSA:3.20.20.140 1 90 2.6E-25 T 29-03-2018 MC49_RS13640 29146bf67e975264a08ae52e8e73ac67 454 Pfam PF03315 Serine dehydratase beta chain 3 155 8.9E-56 T 29-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 MC49_RS13640 29146bf67e975264a08ae52e8e73ac67 454 Gene3D G3DSA:3.30.1330.90 10 158 9.2E-51 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 MC49_RS13640 29146bf67e975264a08ae52e8e73ac67 454 SUPERFAMILY SSF143548 16 158 3.4E-44 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 MC49_RS13640 29146bf67e975264a08ae52e8e73ac67 454 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 2 451 2.0E-220 T 29-03-2018 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 MC49_RS13640 29146bf67e975264a08ae52e8e73ac67 454 Pfam PF03313 Serine dehydratase alpha chain 184 448 1.6E-93 T 29-03-2018 IPR005130 Serine dehydratase-like, alpha subunit MC49_RS13640 29146bf67e975264a08ae52e8e73ac67 454 Gene3D G3DSA:1.10.4100.10 263 444 6.7E-34 T 29-03-2018 MC49_RS11260 ac1a46b14a5d04a329316f0552b32f3d 374 SUPERFAMILY SSF50800 151 268 1.57E-14 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain MC49_RS11260 ac1a46b14a5d04a329316f0552b32f3d 374 SUPERFAMILY SSF50800 5 54 1.57E-14 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain MC49_RS11260 ac1a46b14a5d04a329316f0552b32f3d 374 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 306 366 3.5E-11 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MC49_RS11260 ac1a46b14a5d04a329316f0552b32f3d 374 Gene3D G3DSA:3.10.20.30 282 373 1.3E-12 T 29-03-2018 IPR012675 Beta-grasp domain MC49_RS11260 ac1a46b14a5d04a329316f0552b32f3d 374 Gene3D G3DSA:2.40.33.20 1 281 7.4E-49 T 29-03-2018 MC49_RS11260 ac1a46b14a5d04a329316f0552b32f3d 374 Pfam PF03473 MOSC domain 140 266 4.5E-27 T 29-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 MC49_RS11260 ac1a46b14a5d04a329316f0552b32f3d 374 SUPERFAMILY SSF54292 292 372 6.03E-20 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MC49_RS11260 ac1a46b14a5d04a329316f0552b32f3d 374 SUPERFAMILY SSF141673 8 136 1.01E-27 T 29-03-2018 MC49_RS11260 ac1a46b14a5d04a329316f0552b32f3d 374 Pfam PF03476 MOSC N-terminal beta barrel domain 7 119 3.7E-23 T 29-03-2018 IPR005303 MOSC, N-terminal beta barrel MC49_RS08425 310f58a945a58c6bd1383ab890ae3027 259 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 13 27 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 MC49_RS08425 310f58a945a58c6bd1383ab890ae3027 259 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 9 215 2.8E-40 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MC49_RS08425 310f58a945a58c6bd1383ab890ae3027 259 Gene3D G3DSA:3.40.1010.10 8 128 4.9E-26 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MC49_RS08425 310f58a945a58c6bd1383ab890ae3027 259 Gene3D G3DSA:3.30.950.10 129 249 7.0E-27 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MC49_RS08425 310f58a945a58c6bd1383ab890ae3027 259 SUPERFAMILY SSF53790 7 255 1.96E-63 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MC49_RS08425 310f58a945a58c6bd1383ab890ae3027 259 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 10 255 4.1E-97 T 29-03-2018 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 MC49_RS10265 ff859d4cd96773765533ede82ea9d385 411 Gene3D G3DSA:3.30.420.40 209 397 1.5E-44 T 29-03-2018 MC49_RS10265 ff859d4cd96773765533ede82ea9d385 411 SUPERFAMILY SSF53067 87 392 8.98E-51 T 29-03-2018 MC49_RS10265 ff859d4cd96773765533ede82ea9d385 411 Pfam PF00480 ROK family 87 391 1.5E-80 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 MC49_RS10265 ff859d4cd96773765533ede82ea9d385 411 Gene3D G3DSA:1.10.10.10 20 70 7.2E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS10265 ff859d4cd96773765533ede82ea9d385 411 SUPERFAMILY SSF46785 13 78 2.34E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS10265 ff859d4cd96773765533ede82ea9d385 411 Pfam PF01047 MarR family 24 62 1.1E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MC49_RS10265 ff859d4cd96773765533ede82ea9d385 411 Gene3D G3DSA:3.30.420.40 71 208 2.2E-20 T 29-03-2018 MC49_RS01250 0d0541c0f8b6050fac038b0dd2659848 169 Gene3D G3DSA:3.40.140.10 44 169 2.3E-46 T 29-03-2018 MC49_RS01250 0d0541c0f8b6050fac038b0dd2659848 169 SUPERFAMILY SSF102712 64 139 4.84E-6 T 29-03-2018 MC49_RS01250 0d0541c0f8b6050fac038b0dd2659848 169 Pfam PF04002 RadC-like JAB domain 48 168 5.4E-45 T 29-03-2018 IPR025657 RadC-like JAB domain MC49_RS01250 0d0541c0f8b6050fac038b0dd2659848 169 TIGRFAM TIGR00608 radc: DNA repair protein RadC 28 169 1.3E-43 T 29-03-2018 IPR001405 RadC protein MC49_RS01250 0d0541c0f8b6050fac038b0dd2659848 169 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 118 123 - T 29-03-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site MC49_RS05360 4fc58a3a46cfd437c5250e20498451d8 540 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 347 527 5.8E-70 T 29-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal MC49_RS05360 4fc58a3a46cfd437c5250e20498451d8 540 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 3 346 9.0E-107 T 29-03-2018 IPR028053 Membrane insertase YidC, N-terminal MC49_RS05360 4fc58a3a46cfd437c5250e20498451d8 540 PRINTS PR00701 60kDa inner membrane protein signature 211 229 2.7E-102 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 MC49_RS05360 4fc58a3a46cfd437c5250e20498451d8 540 PRINTS PR00701 60kDa inner membrane protein signature 152 172 2.7E-102 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 MC49_RS05360 4fc58a3a46cfd437c5250e20498451d8 540 PRINTS PR00701 60kDa inner membrane protein signature 318 338 2.7E-102 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 MC49_RS05360 4fc58a3a46cfd437c5250e20498451d8 540 PRINTS PR00701 60kDa inner membrane protein signature 493 516 2.7E-102 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 MC49_RS05360 4fc58a3a46cfd437c5250e20498451d8 540 PRINTS PR00701 60kDa inner membrane protein signature 2 23 2.7E-102 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 MC49_RS05360 4fc58a3a46cfd437c5250e20498451d8 540 PRINTS PR00701 60kDa inner membrane protein signature 60 81 2.7E-102 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 MC49_RS05360 4fc58a3a46cfd437c5250e20498451d8 540 PRINTS PR00701 60kDa inner membrane protein signature 244 259 2.7E-102 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 MC49_RS05360 4fc58a3a46cfd437c5250e20498451d8 540 PRINTS PR00701 60kDa inner membrane protein signature 456 478 2.7E-102 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 MC49_RS05360 4fc58a3a46cfd437c5250e20498451d8 540 PRINTS PR00701 60kDa inner membrane protein signature 409 432 2.7E-102 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 MC49_RS05360 4fc58a3a46cfd437c5250e20498451d8 540 Pfam PF14849 YidC periplasmic domain 55 337 1.1E-83 T 29-03-2018 IPR028053 Membrane insertase YidC, N-terminal MC49_RS05360 4fc58a3a46cfd437c5250e20498451d8 540 PRINTS PR01900 YidC translocation/secretion protein signature 333 349 2.7E-29 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 MC49_RS05360 4fc58a3a46cfd437c5250e20498451d8 540 PRINTS PR01900 YidC translocation/secretion protein signature 482 506 2.7E-29 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 MC49_RS05360 4fc58a3a46cfd437c5250e20498451d8 540 PRINTS PR01900 YidC translocation/secretion protein signature 462 477 2.7E-29 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 MC49_RS05360 4fc58a3a46cfd437c5250e20498451d8 540 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 4 529 26.051 T 29-03-2018 IPR019998 Membrane insertase YidC GO:0016021|GO:0051205 MC49_RS05360 4fc58a3a46cfd437c5250e20498451d8 540 Pfam PF02096 60Kd inner membrane protein 348 527 1.1E-60 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 MC49_RS16575 4088cbff6cb52c778ba462e27759cd85 400 TIGRFAM TIGR00016 ackA: acetate kinase 1 399 1.0E-174 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MC49_RS16575 4088cbff6cb52c778ba462e27759cd85 400 Pfam PF00871 Acetokinase family 6 393 2.6E-166 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MC49_RS16575 4088cbff6cb52c778ba462e27759cd85 400 Gene3D G3DSA:3.30.420.40 5 198 2.7E-67 T 29-03-2018 MC49_RS16575 4088cbff6cb52c778ba462e27759cd85 400 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 206 223 - T 29-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MC49_RS16575 4088cbff6cb52c778ba462e27759cd85 400 PRINTS PR00471 Acetate kinase family signature 380 392 1.1E-47 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MC49_RS16575 4088cbff6cb52c778ba462e27759cd85 400 PRINTS PR00471 Acetate kinase family signature 6 17 1.1E-47 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MC49_RS16575 4088cbff6cb52c778ba462e27759cd85 400 PRINTS PR00471 Acetate kinase family signature 325 341 1.1E-47 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MC49_RS16575 4088cbff6cb52c778ba462e27759cd85 400 PRINTS PR00471 Acetate kinase family signature 176 189 1.1E-47 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MC49_RS16575 4088cbff6cb52c778ba462e27759cd85 400 PRINTS PR00471 Acetate kinase family signature 206 227 1.1E-47 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MC49_RS16575 4088cbff6cb52c778ba462e27759cd85 400 PRINTS PR00471 Acetate kinase family signature 302 315 1.1E-47 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MC49_RS16575 4088cbff6cb52c778ba462e27759cd85 400 SUPERFAMILY SSF53067 159 398 2.29E-85 T 29-03-2018 MC49_RS16575 4088cbff6cb52c778ba462e27759cd85 400 Hamap MF_00020 Acetate kinase [ackA]. 1 400 184.763 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MC49_RS16575 4088cbff6cb52c778ba462e27759cd85 400 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 6 17 - T 29-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MC49_RS16575 4088cbff6cb52c778ba462e27759cd85 400 SUPERFAMILY SSF53067 4 199 7.12E-62 T 29-03-2018 MC49_RS16575 4088cbff6cb52c778ba462e27759cd85 400 Gene3D G3DSA:3.30.420.40 199 400 5.5E-76 T 29-03-2018 MC49_RS16575 4088cbff6cb52c778ba462e27759cd85 400 PIRSF PIRSF000722 2 400 4.5E-142 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MC49_RS17550 157cc2a67198cdcd2b363465b6bd21d3 443 SUPERFAMILY SSF56672 21 373 7.56E-22 T 29-03-2018 MC49_RS17550 157cc2a67198cdcd2b363465b6bd21d3 443 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 75 278 7.5E-22 T 29-03-2018 IPR000477 Reverse transcriptase domain MC49_RS17550 157cc2a67198cdcd2b363465b6bd21d3 443 Gene3D G3DSA:3.30.70.270 45 278 1.4E-23 T 29-03-2018 MC49_RS03510 581d22cf65b2d7db5c166b83239ad5f1 221 Gene3D G3DSA:3.30.1060.10 35 210 3.8E-76 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MC49_RS03510 581d22cf65b2d7db5c166b83239ad5f1 221 Pfam PF01625 Peptide methionine sulfoxide reductase 52 206 7.9E-67 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MC49_RS03510 581d22cf65b2d7db5c166b83239ad5f1 221 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 52 206 1.4E-67 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MC49_RS03510 581d22cf65b2d7db5c166b83239ad5f1 221 SUPERFAMILY SSF55068 18 215 1.26E-80 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MC49_RS03510 581d22cf65b2d7db5c166b83239ad5f1 221 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 50 212 38.471 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MC49_RS00755 33caa41dc3b5e65c5c680f6a7fee2c32 436 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 263 413 3.9E-38 T 29-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 MC49_RS00755 33caa41dc3b5e65c5c680f6a7fee2c32 436 SUPERFAMILY SSF109998 249 431 8.24E-47 T 29-03-2018 IPR027304 Trigger factor/SurA domain MC49_RS00755 33caa41dc3b5e65c5c680f6a7fee2c32 436 SUPERFAMILY SSF54534 99 242 2.16E-37 T 29-03-2018 MC49_RS00755 33caa41dc3b5e65c5c680f6a7fee2c32 436 SUPERFAMILY SSF102735 1 132 3.01E-39 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 MC49_RS00755 33caa41dc3b5e65c5c680f6a7fee2c32 436 Hamap MF_00303 Trigger factor [tig]. 1 419 22.137 T 29-03-2018 IPR005215 Trigger factor GO:0015031 MC49_RS00755 33caa41dc3b5e65c5c680f6a7fee2c32 436 TIGRFAM TIGR00115 tig: trigger factor 13 412 5.2E-142 T 29-03-2018 IPR005215 Trigger factor GO:0015031 MC49_RS00755 33caa41dc3b5e65c5c680f6a7fee2c32 436 Gene3D G3DSA:1.10.3120.10 212 390 5.4E-49 T 29-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 MC49_RS00755 33caa41dc3b5e65c5c680f6a7fee2c32 436 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 159 236 7.9E-14 T 29-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain MC49_RS00755 33caa41dc3b5e65c5c680f6a7fee2c32 436 Gene3D G3DSA:3.30.70.1050 1 119 1.0E-34 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 MC49_RS00755 33caa41dc3b5e65c5c680f6a7fee2c32 436 PIRSF PIRSF003095 1 435 2.7E-129 T 29-03-2018 IPR005215 Trigger factor GO:0015031 MC49_RS00755 33caa41dc3b5e65c5c680f6a7fee2c32 436 Pfam PF05697 Bacterial trigger factor protein (TF) 1 144 2.0E-42 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 MC49_RS09735 4db79719398854a739a5d63c4fecfd50 345 Pfam PF02424 ApbE family 38 320 5.4E-84 T 29-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 MC49_RS09735 4db79719398854a739a5d63c4fecfd50 345 SUPERFAMILY SSF143631 30 342 1.94E-101 T 29-03-2018 IPR003374 ApbE-like domain MC49_RS09735 4db79719398854a739a5d63c4fecfd50 345 Gene3D G3DSA:3.10.520.10 26 330 1.9E-59 T 29-03-2018 MC49_RS09735 4db79719398854a739a5d63c4fecfd50 345 PIRSF PIRSF006268 1 344 2.8E-94 T 29-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 MC49_RS13250 95d40062396a35433ff0e3c5308e521e 152 Gene3D G3DSA:2.60.40.790 10 146 6.7E-20 T 29-03-2018 IPR008978 HSP20-like chaperone MC49_RS13250 95d40062396a35433ff0e3c5308e521e 152 SUPERFAMILY SSF49764 37 146 1.6E-16 T 29-03-2018 IPR008978 HSP20-like chaperone MC49_RS13250 95d40062396a35433ff0e3c5308e521e 152 Pfam PF00011 Hsp20/alpha crystallin family 50 145 3.2E-14 T 29-03-2018 IPR002068 Alpha crystallin/Hsp20 domain MC49_RS03480 49e4d085c44f22acef59ddf94b43bfe7 450 Pfam PF01225 Mur ligase family, catalytic domain 2 98 6.5E-20 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MC49_RS03480 49e4d085c44f22acef59ddf94b43bfe7 450 SUPERFAMILY SSF53623 95 308 2.06E-50 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MC49_RS03480 49e4d085c44f22acef59ddf94b43bfe7 450 Gene3D G3DSA:3.40.50.720 1 90 2.3E-12 T 29-03-2018 MC49_RS03480 49e4d085c44f22acef59ddf94b43bfe7 450 Gene3D G3DSA:3.90.190.20 313 450 1.7E-24 T 29-03-2018 MC49_RS03480 49e4d085c44f22acef59ddf94b43bfe7 450 Pfam PF08245 Mur ligase middle domain 108 291 1.1E-20 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MC49_RS03480 49e4d085c44f22acef59ddf94b43bfe7 450 Pfam PF02875 Mur ligase family, glutamate ligase domain 312 376 1.8E-9 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MC49_RS03480 49e4d085c44f22acef59ddf94b43bfe7 450 SUPERFAMILY SSF53244 312 448 1.96E-36 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MC49_RS03480 49e4d085c44f22acef59ddf94b43bfe7 450 SUPERFAMILY SSF51984 1 90 1.06E-23 T 29-03-2018 MC49_RS03480 49e4d085c44f22acef59ddf94b43bfe7 450 Hamap MF_02020 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase [mpl]. 1 450 58.536 T 29-03-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 MC49_RS03480 49e4d085c44f22acef59ddf94b43bfe7 450 TIGRFAM TIGR01081 mpl: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 2 450 8.0E-249 T 29-03-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 MC49_RS03480 49e4d085c44f22acef59ddf94b43bfe7 450 Gene3D G3DSA:3.40.1190.10 91 312 2.4E-40 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 MC49_RS14890 637d552591d94c2468bf5310cad9068c 243 PRINTS PR01342 Salmonella virulence-associated 28kDa protein signature 181 201 3.6E-10 T 29-03-2018 IPR003519 OspF/SpvC MC49_RS14890 637d552591d94c2468bf5310cad9068c 243 PRINTS PR01342 Salmonella virulence-associated 28kDa protein signature 81 100 3.6E-10 T 29-03-2018 IPR003519 OspF/SpvC MC49_RS14890 637d552591d94c2468bf5310cad9068c 243 PRINTS PR01342 Salmonella virulence-associated 28kDa protein signature 203 219 3.6E-10 T 29-03-2018 IPR003519 OspF/SpvC MC49_RS14890 637d552591d94c2468bf5310cad9068c 243 Gene3D G3DSA:3.30.2430.10 46 240 9.8E-43 T 29-03-2018 MC49_RS14890 637d552591d94c2468bf5310cad9068c 243 Pfam PF03536 Salmonella virulence-associated 28kDa protein 2 240 1.2E-126 T 29-03-2018 IPR003519 OspF/SpvC MC49_RS16505 1f6b814593ff1c493dc3c90a97e1cf0e 325 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 212 225 - T 29-03-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16505 1f6b814593ff1c493dc3c90a97e1cf0e 325 Pfam PF00146 NADH dehydrogenase 18 318 9.5E-121 T 29-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16505 1f6b814593ff1c493dc3c90a97e1cf0e 325 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 11 324 24.159 T 29-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16505 1f6b814593ff1c493dc3c90a97e1cf0e 325 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 57 72 - T 29-03-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS05785 a7c0a5ca301111e9c2d9ec7099d1a6f9 841 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 413 841 2.4E-104 T 29-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 MC49_RS05785 a7c0a5ca301111e9c2d9ec7099d1a6f9 841 Pfam PF16168 Adhesin of bacterial autotransporter system, probable stalk 197 247 4.2E-7 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system MC49_RS05785 a7c0a5ca301111e9c2d9ec7099d1a6f9 841 Pfam PF16168 Adhesin of bacterial autotransporter system, probable stalk 216 266 4.4E-7 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system MC49_RS05785 a7c0a5ca301111e9c2d9ec7099d1a6f9 841 Pfam PF16168 Adhesin of bacterial autotransporter system, probable stalk 161 210 1.5E-7 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system MC49_RS05785 a7c0a5ca301111e9c2d9ec7099d1a6f9 841 Pfam PF03797 Autotransporter beta-domain 580 819 1.4E-56 T 29-03-2018 IPR005546 Autotransporter beta-domain MC49_RS05785 a7c0a5ca301111e9c2d9ec7099d1a6f9 841 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 165 195 1.4E-5 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system MC49_RS05785 a7c0a5ca301111e9c2d9ec7099d1a6f9 841 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 239 271 4.5E-5 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system MC49_RS05785 a7c0a5ca301111e9c2d9ec7099d1a6f9 841 TIGRFAM TIGR04415 O_hepto_targRPT: autotransporter passenger strand-loop-strand repeat 203 237 6.6E-9 T 29-03-2018 IPR030930 Adhesin of bacterial autotransporter system MC49_RS05785 a7c0a5ca301111e9c2d9ec7099d1a6f9 841 Gene3D G3DSA:2.40.128.130 535 841 2.0E-60 T 29-03-2018 MC49_RS05785 a7c0a5ca301111e9c2d9ec7099d1a6f9 841 SMART SM00869 577 830 8.5E-49 T 29-03-2018 IPR005546 Autotransporter beta-domain MC49_RS05785 a7c0a5ca301111e9c2d9ec7099d1a6f9 841 Pfam PF03212 Pertactin 400 517 5.4E-20 T 29-03-2018 IPR004899 Pertactin, central region MC49_RS05785 a7c0a5ca301111e9c2d9ec7099d1a6f9 841 PRINTS PR01484 Pertactin virulence factor family signature 557 575 1.5E-5 T 29-03-2018 IPR003991 Pertactin virulence factor family GO:0007155 MC49_RS05785 a7c0a5ca301111e9c2d9ec7099d1a6f9 841 PRINTS PR01484 Pertactin virulence factor family signature 821 841 1.5E-5 T 29-03-2018 IPR003991 Pertactin virulence factor family GO:0007155 MC49_RS05785 a7c0a5ca301111e9c2d9ec7099d1a6f9 841 PRINTS PR01484 Pertactin virulence factor family signature 709 726 1.5E-5 T 29-03-2018 IPR003991 Pertactin virulence factor family GO:0007155 MC49_RS05785 a7c0a5ca301111e9c2d9ec7099d1a6f9 841 PRINTS PR01484 Pertactin virulence factor family signature 728 751 1.5E-5 T 29-03-2018 IPR003991 Pertactin virulence factor family GO:0007155 MC49_RS05785 a7c0a5ca301111e9c2d9ec7099d1a6f9 841 PRINTS PR01484 Pertactin virulence factor family signature 757 778 1.5E-5 T 29-03-2018 IPR003991 Pertactin virulence factor family GO:0007155 MC49_RS05785 a7c0a5ca301111e9c2d9ec7099d1a6f9 841 PRINTS PR01484 Pertactin virulence factor family signature 796 821 1.5E-5 T 29-03-2018 IPR003991 Pertactin virulence factor family GO:0007155 MC49_RS05785 a7c0a5ca301111e9c2d9ec7099d1a6f9 841 SUPERFAMILY SSF51126 166 518 8.16E-24 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor MC49_RS05785 a7c0a5ca301111e9c2d9ec7099d1a6f9 841 SUPERFAMILY SSF103515 544 841 2.75E-55 T 29-03-2018 IPR005546 Autotransporter beta-domain MC49_RS06200 df1ae4d31d998a8fc80e1dedf1c3bc86 210 Hamap MF_00202 Isopentenyl-diphosphate Delta-isomerase [idi]. 40 210 31.769 T 29-03-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 MC49_RS06200 df1ae4d31d998a8fc80e1dedf1c3bc86 210 TIGRFAM TIGR02150 IPP_isom_1: isopentenyl-diphosphate delta-isomerase 42 198 5.8E-39 T 29-03-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 MC49_RS06200 df1ae4d31d998a8fc80e1dedf1c3bc86 210 Gene3D G3DSA:3.90.79.10 34 204 5.4E-33 T 29-03-2018 MC49_RS06200 df1ae4d31d998a8fc80e1dedf1c3bc86 210 SUPERFAMILY SSF55811 41 202 2.57E-47 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MC49_RS06200 df1ae4d31d998a8fc80e1dedf1c3bc86 210 Pfam PF00293 NUDIX domain 66 195 2.7E-23 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MC49_RS06200 df1ae4d31d998a8fc80e1dedf1c3bc86 210 PIRSF PIRSF018427 32 209 4.6E-54 T 29-03-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 MC49_RS00705 634cc9a8d1b3862b400bf507c2213e65 158 SUPERFAMILY SSF54909 62 151 7.11E-20 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel MC49_RS00705 634cc9a8d1b3862b400bf507c2213e65 158 SUPERFAMILY SSF46785 2 92 1.44E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS00705 634cc9a8d1b3862b400bf507c2213e65 158 Pfam PF01037 Lrp/AsnC ligand binding domain 68 142 1.1E-19 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MC49_RS00705 634cc9a8d1b3862b400bf507c2213e65 158 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 49 2.5E-17 T 29-03-2018 MC49_RS00705 634cc9a8d1b3862b400bf507c2213e65 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 1.1E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MC49_RS00705 634cc9a8d1b3862b400bf507c2213e65 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 1.1E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MC49_RS00705 634cc9a8d1b3862b400bf507c2213e65 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 1.1E-11 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MC49_RS00705 634cc9a8d1b3862b400bf507c2213e65 158 SMART SM00344 2 111 3.8E-45 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MC49_RS00705 634cc9a8d1b3862b400bf507c2213e65 158 Gene3D G3DSA:3.30.70.920 55 148 5.9E-26 T 29-03-2018 MC49_RS00705 634cc9a8d1b3862b400bf507c2213e65 158 Gene3D G3DSA:1.10.10.10 3 54 1.8E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS11985 2673ec64e00719e87db6b46334656a20 337 Gene3D G3DSA:1.10.240.10 208 330 2.2E-30 T 29-03-2018 MC49_RS11985 2673ec64e00719e87db6b46334656a20 337 SUPERFAMILY SSF52374 9 334 9.18E-72 T 29-03-2018 MC49_RS11985 2673ec64e00719e87db6b46334656a20 337 Pfam PF00579 tRNA synthetases class I (W and Y) 7 289 1.6E-46 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS11985 2673ec64e00719e87db6b46334656a20 337 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 8 334 1.5E-61 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MC49_RS11985 2673ec64e00719e87db6b46334656a20 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 20 36 1.1E-20 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MC49_RS11985 2673ec64e00719e87db6b46334656a20 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 149 170 1.1E-20 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MC49_RS11985 2673ec64e00719e87db6b46334656a20 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 201 211 1.1E-20 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MC49_RS11985 2673ec64e00719e87db6b46334656a20 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 71 90 1.1E-20 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MC49_RS11985 2673ec64e00719e87db6b46334656a20 337 Gene3D G3DSA:3.40.50.620 6 207 2.6E-49 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS02250 322c685d17a389cb661d46ffb04bd13e 110 TIGRFAM TIGR03757 conj_TIGR03757: integrating conjugative element protein, PFL_4709 family 1 105 2.9E-34 T 29-03-2018 IPR011090 Integrating conjugative element protein, PFL4709 MC49_RS02250 322c685d17a389cb661d46ffb04bd13e 110 Pfam PF07511 Protein of unknown function (DUF1525) 1 107 5.4E-33 T 29-03-2018 IPR011090 Integrating conjugative element protein, PFL4709 MC49_RS11580 22c5d27d852610fa6271f8f0819f68a1 143 SUPERFAMILY SSF54593 1 130 1.27E-27 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MC49_RS11580 22c5d27d852610fa6271f8f0819f68a1 143 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 112 3.0E-11 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MC49_RS11580 22c5d27d852610fa6271f8f0819f68a1 143 Gene3D G3DSA:3.10.180.10 1 137 4.6E-26 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MC49_RS03405 2fefe5991e339a3f6328c2e1b8892421 444 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 157 254 2.5E-19 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MC49_RS03405 2fefe5991e339a3f6328c2e1b8892421 444 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 3 444 47.799 T 29-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MC49_RS03405 2fefe5991e339a3f6328c2e1b8892421 444 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 234 249 1.8E-12 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MC49_RS03405 2fefe5991e339a3f6328c2e1b8892421 444 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 95 109 1.8E-12 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MC49_RS03405 2fefe5991e339a3f6328c2e1b8892421 444 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 174 193 1.8E-12 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MC49_RS03405 2fefe5991e339a3f6328c2e1b8892421 444 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 373 441 3.1E-15 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MC49_RS03405 2fefe5991e339a3f6328c2e1b8892421 444 Gene3D G3DSA:3.40.120.10 156 268 1.9E-32 T 29-03-2018 MC49_RS03405 2fefe5991e339a3f6328c2e1b8892421 444 Gene3D G3DSA:3.40.120.10 3 154 2.1E-48 T 29-03-2018 MC49_RS03405 2fefe5991e339a3f6328c2e1b8892421 444 Gene3D G3DSA:3.30.310.50 374 444 6.9E-19 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MC49_RS03405 2fefe5991e339a3f6328c2e1b8892421 444 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 4 135 4.0E-45 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MC49_RS03405 2fefe5991e339a3f6328c2e1b8892421 444 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 258 364 5.4E-32 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MC49_RS03405 2fefe5991e339a3f6328c2e1b8892421 444 SUPERFAMILY SSF53738 258 365 9.03E-31 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MC49_RS03405 2fefe5991e339a3f6328c2e1b8892421 444 SUPERFAMILY SSF53738 156 255 5.89E-29 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MC49_RS03405 2fefe5991e339a3f6328c2e1b8892421 444 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 96 105 - T 29-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MC49_RS03405 2fefe5991e339a3f6328c2e1b8892421 444 SUPERFAMILY SSF53738 2 181 1.26E-48 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MC49_RS03405 2fefe5991e339a3f6328c2e1b8892421 444 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 7 442 2.5E-196 T 29-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MC49_RS03405 2fefe5991e339a3f6328c2e1b8892421 444 SUPERFAMILY SSF55957 357 443 2.62E-22 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MC49_RS03405 2fefe5991e339a3f6328c2e1b8892421 444 Gene3D G3DSA:3.40.120.10 269 373 1.5E-28 T 29-03-2018 MC49_RS08000 5c066cdcf615233377ee08fd57ee1ad9 149 Pfam PF00258 Flavodoxin 6 140 1.2E-18 T 29-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 MC49_RS08000 5c066cdcf615233377ee08fd57ee1ad9 149 Gene3D G3DSA:3.40.50.360 1 149 5.6E-25 T 29-03-2018 IPR029039 Flavoprotein-like domain MC49_RS08000 5c066cdcf615233377ee08fd57ee1ad9 149 SUPERFAMILY SSF52218 1 148 1.71E-33 T 29-03-2018 IPR029039 Flavoprotein-like domain MC49_RS08000 5c066cdcf615233377ee08fd57ee1ad9 149 PRINTS PR00369 Flavodoxin signature 84 94 6.1E-6 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MC49_RS08000 5c066cdcf615233377ee08fd57ee1ad9 149 PRINTS PR00369 Flavodoxin signature 108 127 6.1E-6 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MC49_RS08000 5c066cdcf615233377ee08fd57ee1ad9 149 PRINTS PR00369 Flavodoxin signature 5 18 6.1E-6 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MC49_RS08000 5c066cdcf615233377ee08fd57ee1ad9 149 PRINTS PR00369 Flavodoxin signature 53 64 6.1E-6 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MC49_RS09920 e74f1bbbc5f6d32d1c8484a2ca9eaece 114 Gene3D G3DSA:3.30.160.100 1 99 1.1E-24 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 MC49_RS09920 e74f1bbbc5f6d32d1c8484a2ca9eaece 114 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 91 2.2E-21 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 MC49_RS09920 e74f1bbbc5f6d32d1c8484a2ca9eaece 114 SUPERFAMILY SSF69754 2 105 5.49E-32 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 MC49_RS09920 e74f1bbbc5f6d32d1c8484a2ca9eaece 114 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 98 1.4E-32 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 MC49_RS05495 0548533b8b5de90c52b20de6fb934b27 330 TIGRFAM TIGR00816 tdt: C4-dicarboxylate transporter/malic acid transport protein 16 317 9.2E-72 T 29-03-2018 IPR011552 Tellurite resistance protein TehA/malic acid transport protein GO:0016021 MC49_RS05495 0548533b8b5de90c52b20de6fb934b27 330 Pfam PF03595 Voltage-dependent anion channel 16 311 1.2E-35 T 29-03-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 MC49_RS13245 f84450b77aeb0fe11593992289078a1a 146 SUPERFAMILY SSF52402 2 146 4.81E-23 T 29-03-2018 MC49_RS13245 f84450b77aeb0fe11593992289078a1a 146 Pfam PF00582 Universal stress protein family 1 146 9.3E-17 T 29-03-2018 IPR006016 UspA GO:0006950 MC49_RS13245 f84450b77aeb0fe11593992289078a1a 146 PRINTS PR01438 Universal stress protein signature 106 118 1.5E-12 T 29-03-2018 IPR006015 Universal stress protein A MC49_RS13245 f84450b77aeb0fe11593992289078a1a 146 PRINTS PR01438 Universal stress protein signature 124 146 1.5E-12 T 29-03-2018 IPR006015 Universal stress protein A MC49_RS13245 f84450b77aeb0fe11593992289078a1a 146 PRINTS PR01438 Universal stress protein signature 2 20 1.5E-12 T 29-03-2018 IPR006015 Universal stress protein A MC49_RS13245 f84450b77aeb0fe11593992289078a1a 146 Gene3D G3DSA:3.40.50.620 1 145 5.5E-19 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS03040 fbef1b81c501509bd4ab049718c4d379 300 Pfam PF03466 LysR substrate binding domain 116 286 4.9E-10 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS03040 fbef1b81c501509bd4ab049718c4d379 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.4E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS03040 fbef1b81c501509bd4ab049718c4d379 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.4E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS03040 fbef1b81c501509bd4ab049718c4d379 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.4E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS03040 fbef1b81c501509bd4ab049718c4d379 300 Gene3D G3DSA:3.40.190.10 91 176 1.2E-31 T 29-03-2018 MC49_RS03040 fbef1b81c501509bd4ab049718c4d379 300 Gene3D G3DSA:3.40.190.10 177 263 1.3E-7 T 29-03-2018 MC49_RS03040 fbef1b81c501509bd4ab049718c4d379 300 TIGRFAM TIGR03298 argP: transcriptional regulator, ArgP family 4 292 7.7E-95 T 29-03-2018 IPR017685 HTH-type transcriptional regulator ArgP MC49_RS03040 fbef1b81c501509bd4ab049718c4d379 300 Gene3D G3DSA:1.10.10.10 1 83 7.1E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS03040 fbef1b81c501509bd4ab049718c4d379 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 64 8.6E-13 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS03040 fbef1b81c501509bd4ab049718c4d379 300 SUPERFAMILY SSF53850 91 290 2.53E-16 T 29-03-2018 MC49_RS03040 fbef1b81c501509bd4ab049718c4d379 300 SUPERFAMILY SSF46785 4 96 4.14E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS02555 92c202003e2d42d887266fbf3dd79d8e 633 Gene3D G3DSA:3.30.70.1290 2 123 3.5E-18 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MC49_RS02555 92c202003e2d42d887266fbf3dd79d8e 633 SUPERFAMILY SSF55681 232 527 5.18E-36 T 29-03-2018 MC49_RS02555 92c202003e2d42d887266fbf3dd79d8e 633 Gene3D G3DSA:3.30.930.10 230 534 5.0E-25 T 29-03-2018 MC49_RS02555 92c202003e2d42d887266fbf3dd79d8e 633 SMART SM01321 9 124 5.3E-21 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MC49_RS02555 92c202003e2d42d887266fbf3dd79d8e 633 Pfam PF01797 Transposase IS200 like 22 122 6.0E-9 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MC49_RS02555 92c202003e2d42d887266fbf3dd79d8e 633 Pfam PF13393 Histidyl-tRNA synthetase 230 522 4.5E-18 T 29-03-2018 MC49_RS02555 92c202003e2d42d887266fbf3dd79d8e 633 SUPERFAMILY SSF143422 3 122 2.88E-17 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MC49_RS17135 6b20ef0940bc641e93e8d3b7848bee6d 319 SMART SM00363 20 79 4.8E-7 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MC49_RS17135 6b20ef0940bc641e93e8d3b7848bee6d 319 Gene3D G3DSA:3.30.2350.10 92 317 4.8E-68 T 29-03-2018 MC49_RS17135 6b20ef0940bc641e93e8d3b7848bee6d 319 SUPERFAMILY SSF55174 19 70 1.02E-8 T 29-03-2018 MC49_RS17135 6b20ef0940bc641e93e8d3b7848bee6d 319 Pfam PF01479 S4 domain 20 66 2.6E-9 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MC49_RS17135 6b20ef0940bc641e93e8d3b7848bee6d 319 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 140 154 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS17135 6b20ef0940bc641e93e8d3b7848bee6d 319 SUPERFAMILY SSF55120 95 314 1.14E-65 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS17135 6b20ef0940bc641e93e8d3b7848bee6d 319 Gene3D G3DSA:3.10.290.10 3 78 3.5E-14 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MC49_RS17135 6b20ef0940bc641e93e8d3b7848bee6d 319 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 17 314 6.1E-93 T 29-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS17135 6b20ef0940bc641e93e8d3b7848bee6d 319 Pfam PF00849 RNA pseudouridylate synthase 101 248 1.2E-29 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS08310 c36405cc8b129ef977d45d5ae76e42bc 198 SUPERFAMILY SSF46689 6 78 4.47E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS08310 c36405cc8b129ef977d45d5ae76e42bc 198 Gene3D G3DSA:1.10.10.60 6 50 3.3E-18 T 29-03-2018 MC49_RS08310 c36405cc8b129ef977d45d5ae76e42bc 198 ProSitePatterns PS01081 TetR-type HTH domain signature. 30 61 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MC49_RS08310 c36405cc8b129ef977d45d5ae76e42bc 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 63 5.7E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS08310 c36405cc8b129ef977d45d5ae76e42bc 198 Gene3D G3DSA:1.10.10.60 51 146 5.8E-12 T 29-03-2018 MC49_RS08310 c36405cc8b129ef977d45d5ae76e42bc 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 5.0E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS08310 c36405cc8b129ef977d45d5ae76e42bc 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 5.0E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS00575 838b71d6586ca0c965afcc2f5f9bf032 601 SUPERFAMILY SSF51735 422 552 3.44E-27 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS00575 838b71d6586ca0c965afcc2f5f9bf032 601 Pfam PF00999 Sodium/hydrogen exchanger family 16 388 4.6E-77 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 MC49_RS00575 838b71d6586ca0c965afcc2f5f9bf032 601 Gene3D G3DSA:3.40.50.720 413 538 5.0E-18 T 29-03-2018 MC49_RS00575 838b71d6586ca0c965afcc2f5f9bf032 601 Gene3D G3DSA:1.20.91.10 243 327 1.0E-5 T 29-03-2018 MC49_RS00575 838b71d6586ca0c965afcc2f5f9bf032 601 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 17 298 5.1E-75 T 29-03-2018 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 MC49_RS00575 838b71d6586ca0c965afcc2f5f9bf032 601 Pfam PF02254 TrkA-N domain 425 537 6.7E-23 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MC49_RS12495 984f913b96c370a9b815cffacb85d6ac 2504 Pfam PF03538 Salmonella virulence plasmid 28.1kDa A protein 99 223 3.5E-18 T 29-03-2018 IPR018003 Insecticidal toxin complex/plasmid virulence protein MC49_RS12495 984f913b96c370a9b815cffacb85d6ac 2504 Gene3D G3DSA:1.10.287.510 2054 2245 4.0E-4 T 29-03-2018 MC49_RS14245 69081f7c39ea9ba34f6a11034ad84391 236 SUPERFAMILY SSF63848 130 234 8.5E-30 T 29-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 MC49_RS14245 69081f7c39ea9ba34f6a11034ad84391 236 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 5 236 28.258 T 29-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 MC49_RS14245 69081f7c39ea9ba34f6a11034ad84391 236 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 6 235 1.4E-69 T 29-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 MC49_RS14245 69081f7c39ea9ba34f6a11034ad84391 236 Pfam PF05209 Septum formation inhibitor MinC, N-terminal domain 1 102 9.1E-29 T 29-03-2018 IPR007874 Septum formation inhibitor MinC, N-terminal GO:0051302 MC49_RS14245 69081f7c39ea9ba34f6a11034ad84391 236 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 133 232 8.1E-30 T 29-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 MC49_RS14245 69081f7c39ea9ba34f6a11034ad84391 236 Gene3D G3DSA:2.160.20.70 113 236 3.9E-30 T 29-03-2018 MC49_RS11145 bc7033608f7d610db6e7b34a8e92d118 581 TIGRFAM TIGR02203 MsbA_lipidA: lipid A export permease/ATP-binding protein MsbA 11 580 8.3E-254 T 29-03-2018 IPR011917 ABC transporter, lipid A export, MsbA GO:0005524|GO:0016021|GO:0034040 MC49_RS11145 bc7033608f7d610db6e7b34a8e92d118 581 Gene3D G3DSA:3.40.50.300 327 581 9.9E-82 T 29-03-2018 MC49_RS11145 bc7033608f7d610db6e7b34a8e92d118 581 SUPERFAMILY SSF52540 331 579 4.87E-96 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS11145 bc7033608f7d610db6e7b34a8e92d118 581 Pfam PF00664 ABC transporter transmembrane region 27 296 3.8E-58 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MC49_RS11145 bc7033608f7d610db6e7b34a8e92d118 581 ProSitePatterns PS00211 ABC transporters family signature. 480 494 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS11145 bc7033608f7d610db6e7b34a8e92d118 581 SMART SM00382 367 554 4.6E-19 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS11145 bc7033608f7d610db6e7b34a8e92d118 581 SUPERFAMILY SSF90123 13 326 1.05E-69 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MC49_RS11145 bc7033608f7d610db6e7b34a8e92d118 581 Pfam PF00005 ABC transporter 358 508 3.0E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS11145 bc7033608f7d610db6e7b34a8e92d118 581 Gene3D G3DSA:1.20.1560.10 7 326 6.2E-62 T 29-03-2018 MC49_RS11085 a554bc5e5002a1587009c90eeb405f83 430 SUPERFAMILY SSF55681 116 424 1.66E-102 T 29-03-2018 MC49_RS11085 a554bc5e5002a1587009c90eeb405f83 430 Gene3D G3DSA:3.30.930.10 105 430 1.8E-96 T 29-03-2018 MC49_RS11085 a554bc5e5002a1587009c90eeb405f83 430 PRINTS PR00981 Seryl-tRNA synthetase signature 357 373 6.1E-35 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MC49_RS11085 a554bc5e5002a1587009c90eeb405f83 430 PRINTS PR00981 Seryl-tRNA synthetase signature 322 335 6.1E-35 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MC49_RS11085 a554bc5e5002a1587009c90eeb405f83 430 PRINTS PR00981 Seryl-tRNA synthetase signature 270 282 6.1E-35 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MC49_RS11085 a554bc5e5002a1587009c90eeb405f83 430 PRINTS PR00981 Seryl-tRNA synthetase signature 282 295 6.1E-35 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MC49_RS11085 a554bc5e5002a1587009c90eeb405f83 430 PRINTS PR00981 Seryl-tRNA synthetase signature 339 355 6.1E-35 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MC49_RS11085 a554bc5e5002a1587009c90eeb405f83 430 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 107 1.4E-31 T 29-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 MC49_RS11085 a554bc5e5002a1587009c90eeb405f83 430 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 428 41.411 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MC49_RS11085 a554bc5e5002a1587009c90eeb405f83 430 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 423 6.0E-179 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MC49_RS11085 a554bc5e5002a1587009c90eeb405f83 430 SUPERFAMILY SSF46589 1 112 7.85E-31 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 MC49_RS11085 a554bc5e5002a1587009c90eeb405f83 430 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 228 406 3.1E-37 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS11085 a554bc5e5002a1587009c90eeb405f83 430 PIRSF PIRSF001529 1 430 1.6E-184 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MC49_RS11085 a554bc5e5002a1587009c90eeb405f83 430 Gene3D G3DSA:1.10.287.40 2 104 2.0E-24 T 29-03-2018 MC49_RS02805 8b3b683a3f470827f4c727f410bdedc3 104 SUPERFAMILY SSF47413 5 75 8.04E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS02805 8b3b683a3f470827f4c727f410bdedc3 104 Gene3D G3DSA:1.10.260.40 2 99 2.9E-16 T 29-03-2018 MC49_RS02805 8b3b683a3f470827f4c727f410bdedc3 104 Pfam PF01381 Helix-turn-helix 14 68 6.5E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS02805 8b3b683a3f470827f4c727f410bdedc3 104 SMART SM00530 13 68 2.7E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS09160 5a367b78f8387a215a81f0708e3e2029 233 Hamap MF_01684 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase [mtnN]. 2 229 46.129 T 29-03-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MC49_RS09160 5a367b78f8387a215a81f0708e3e2029 233 SUPERFAMILY SSF53167 1 226 5.5E-73 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MC49_RS09160 5a367b78f8387a215a81f0708e3e2029 233 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 2 227 2.1E-109 T 29-03-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MC49_RS09160 5a367b78f8387a215a81f0708e3e2029 233 Pfam PF01048 Phosphorylase superfamily 2 227 2.0E-48 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MC49_RS09160 5a367b78f8387a215a81f0708e3e2029 233 Gene3D G3DSA:3.40.50.1580 1 231 4.7E-55 T 29-03-2018 MC49_RS04390 6cbd681f4b6509d9191c3da24bb544ef 772 Pfam PF07670 Nucleoside recognition 355 445 6.5E-13 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 MC49_RS04390 6cbd681f4b6509d9191c3da24bb544ef 772 Pfam PF07670 Nucleoside recognition 514 691 4.4E-36 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 MC49_RS04390 6cbd681f4b6509d9191c3da24bb544ef 772 Pfam PF02421 Ferrous iron transport protein B 6 163 9.4E-63 T 29-03-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 MC49_RS04390 6cbd681f4b6509d9191c3da24bb544ef 772 SUPERFAMILY SSF52540 4 168 2.45E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS04390 6cbd681f4b6509d9191c3da24bb544ef 772 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 10 689 8.9E-224 T 29-03-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 MC49_RS04390 6cbd681f4b6509d9191c3da24bb544ef 772 Gene3D G3DSA:3.40.50.300 2 295 2.6E-34 T 29-03-2018 MC49_RS04390 6cbd681f4b6509d9191c3da24bb544ef 772 Pfam PF07664 Ferrous iron transport protein B C terminus 457 509 5.0E-22 T 29-03-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 MC49_RS13785 13269672ded7a444c51bf9fd148c9d99 261 Gene3D G3DSA:3.40.50.300 53 260 3.7E-22 T 29-03-2018 MC49_RS13785 13269672ded7a444c51bf9fd148c9d99 261 Pfam PF02562 PhoH-like protein 56 260 6.7E-75 T 29-03-2018 IPR003714 PhoH-like protein GO:0005524 MC49_RS13785 13269672ded7a444c51bf9fd148c9d99 261 SUPERFAMILY SSF52540 56 235 3.05E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS17745 711d3e9500fb0d15a0b245f52fcce176 71 Pfam PF14354 Restriction alleviation protein Lar 7 58 6.9E-10 T 29-03-2018 MC49_RS17745 711d3e9500fb0d15a0b245f52fcce176 71 TIGRFAM TIGR03655 anti_R_Lar: restriction alleviation protein, Lar family 8 58 1.2E-13 T 29-03-2018 IPR019908 Endodeoxyribonuclease toxin RalR MC49_RS16730 a0a748e56b9dc1d67ddbea5d3d14df52 717 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 498 591 4.3E-28 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 MC49_RS16730 a0a748e56b9dc1d67ddbea5d3d14df52 717 Pfam PF00378 Enoyl-CoA hydratase/isomerase 23 208 3.1E-37 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 MC49_RS16730 a0a748e56b9dc1d67ddbea5d3d14df52 717 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 316 495 1.4E-53 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 MC49_RS16730 a0a748e56b9dc1d67ddbea5d3d14df52 717 SUPERFAMILY SSF52096 10 303 1.93E-64 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MC49_RS16730 a0a748e56b9dc1d67ddbea5d3d14df52 717 SUPERFAMILY SSF48179 498 593 1.02E-29 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MC49_RS16730 a0a748e56b9dc1d67ddbea5d3d14df52 717 Gene3D G3DSA:3.90.226.10 1 272 6.8E-56 T 29-03-2018 MC49_RS16730 a0a748e56b9dc1d67ddbea5d3d14df52 717 TIGRFAM TIGR02440 FadJ: fatty oxidation complex, alpha subunit FadJ 11 717 0.0 T 29-03-2018 IPR012802 Fatty oxidation complex, alpha subunit FadJ GO:0003857|GO:0004300|GO:0006635|GO:0008692|GO:0051287|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 MC49_RS16730 a0a748e56b9dc1d67ddbea5d3d14df52 717 SUPERFAMILY SSF51735 315 495 2.54E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS16730 a0a748e56b9dc1d67ddbea5d3d14df52 717 Gene3D G3DSA:1.10.1040.10 497 593 5.3E-27 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MC49_RS16730 a0a748e56b9dc1d67ddbea5d3d14df52 717 Gene3D G3DSA:1.10.1040.10 624 716 1.9E-16 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MC49_RS16730 a0a748e56b9dc1d67ddbea5d3d14df52 717 SUPERFAMILY SSF48179 625 717 6.04E-22 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 MC49_RS16730 a0a748e56b9dc1d67ddbea5d3d14df52 717 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 495 519 - T 29-03-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 MC49_RS16730 a0a748e56b9dc1d67ddbea5d3d14df52 717 Gene3D G3DSA:3.40.50.720 273 496 3.1E-51 T 29-03-2018 MC49_RS05235 9a97d879175ceb184102b6d2e9d36378 492 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 315 339 1.1E-19 T 29-03-2018 MC49_RS05235 9a97d879175ceb184102b6d2e9d36378 492 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 180 196 1.1E-19 T 29-03-2018 MC49_RS05235 9a97d879175ceb184102b6d2e9d36378 492 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 204 218 1.1E-19 T 29-03-2018 MC49_RS05235 9a97d879175ceb184102b6d2e9d36378 492 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 288 300 1.1E-19 T 29-03-2018 MC49_RS05235 9a97d879175ceb184102b6d2e9d36378 492 Gene3D G3DSA:3.40.50.150 178 476 4.3E-51 T 29-03-2018 MC49_RS05235 9a97d879175ceb184102b6d2e9d36378 492 SUPERFAMILY SSF53335 3 491 8.58E-113 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS05235 9a97d879175ceb184102b6d2e9d36378 492 Pfam PF02384 N-6 DNA Methylase 161 460 2.1E-63 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 MC49_RS05235 9a97d879175ceb184102b6d2e9d36378 492 Pfam PF12161 HsdM N-terminal domain 3 145 1.9E-11 T 29-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain MC49_RS05235 9a97d879175ceb184102b6d2e9d36378 492 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 291 297 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MC49_RS15950 d43ee283e4cd1dc81cf3d0ae51aedac0 98 TIGRFAM TIGR00987 himA: integration host factor, alpha subunit 2 97 1.1E-49 T 29-03-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 MC49_RS15950 d43ee283e4cd1dc81cf3d0ae51aedac0 98 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 48 67 - T 29-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 MC49_RS15950 d43ee283e4cd1dc81cf3d0ae51aedac0 98 SUPERFAMILY SSF47729 3 92 2.06E-30 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 MC49_RS15950 d43ee283e4cd1dc81cf3d0ae51aedac0 98 Gene3D G3DSA:4.10.520.10 1 98 1.2E-32 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 MC49_RS15950 d43ee283e4cd1dc81cf3d0ae51aedac0 98 SMART SM00411 3 92 6.1E-42 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MC49_RS15950 d43ee283e4cd1dc81cf3d0ae51aedac0 98 Pfam PF00216 Bacterial DNA-binding protein 3 91 6.6E-30 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MC49_RS15950 d43ee283e4cd1dc81cf3d0ae51aedac0 98 PRINTS PR01727 Prokaryotic integration host factor signature 76 90 1.0E-16 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MC49_RS15950 d43ee283e4cd1dc81cf3d0ae51aedac0 98 PRINTS PR01727 Prokaryotic integration host factor signature 42 57 1.0E-16 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MC49_RS15950 d43ee283e4cd1dc81cf3d0ae51aedac0 98 PRINTS PR01727 Prokaryotic integration host factor signature 60 73 1.0E-16 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MC49_RS15950 d43ee283e4cd1dc81cf3d0ae51aedac0 98 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 1 97 30.073 T 29-03-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 MC49_RS01925 199ee054ffcd8e75d7e29573020bedcc 548 TIGRFAM TIGR03377 glycerol3P_GlpA: glycerol-3-phosphate dehydrogenase, anaerobic, A subunit 10 537 3.1E-253 T 29-03-2018 IPR017752 Glycerol-3-phosphate dehydrogenase, GlpA subunit GO:0004368|GO:0005886|GO:0010181|GO:0046174|GO:0050660|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 MC49_RS01925 199ee054ffcd8e75d7e29573020bedcc 548 Pfam PF04324 BFD-like [2Fe-2S] binding domain 432 484 8.3E-9 T 29-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain MC49_RS01925 199ee054ffcd8e75d7e29573020bedcc 548 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 14 31 - T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 MC49_RS01925 199ee054ffcd8e75d7e29573020bedcc 548 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 352 362 - T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 MC49_RS01925 199ee054ffcd8e75d7e29573020bedcc 548 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 9 21 1.2E-20 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 MC49_RS01925 199ee054ffcd8e75d7e29573020bedcc 548 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 38 50 1.2E-20 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 MC49_RS01925 199ee054ffcd8e75d7e29573020bedcc 548 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 311 317 1.2E-20 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 MC49_RS01925 199ee054ffcd8e75d7e29573020bedcc 548 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 22 32 1.2E-20 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 MC49_RS01925 199ee054ffcd8e75d7e29573020bedcc 548 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 347 359 1.2E-20 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 MC49_RS01925 199ee054ffcd8e75d7e29573020bedcc 548 Gene3D G3DSA:3.50.50.60 2 393 2.9E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS01925 199ee054ffcd8e75d7e29573020bedcc 548 SUPERFAMILY SSF51905 9 321 1.46E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS01925 199ee054ffcd8e75d7e29573020bedcc 548 Pfam PF01266 FAD dependent oxidoreductase 10 359 2.6E-51 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MC49_RS11275 289143c8bb7b7030ebf32eac1d8d79f2 425 TIGRFAM TIGR00155 pqiA_fam: integral membrane protein, PqiA family 4 409 7.5E-142 T 29-03-2018 IPR005219 Conserved hypothetical protein CHP00155 MC49_RS11275 289143c8bb7b7030ebf32eac1d8d79f2 425 Pfam PF04403 Paraquat-inducible protein A 51 201 1.9E-37 T 29-03-2018 IPR007498 Paraquat-inducible protein A MC49_RS11275 289143c8bb7b7030ebf32eac1d8d79f2 425 Pfam PF04403 Paraquat-inducible protein A 255 410 2.2E-53 T 29-03-2018 IPR007498 Paraquat-inducible protein A MC49_RS16430 67b2f67cbe35265c12de13b8275fec2d 480 SUPERFAMILY SSF56634 4 475 5.37E-209 T 29-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MC49_RS16430 67b2f67cbe35265c12de13b8275fec2d 480 PIRSF PIRSF038928 1 480 6.3E-219 T 29-03-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MC49_RS16430 67b2f67cbe35265c12de13b8275fec2d 480 SMART SM01060 7 391 4.0E-279 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MC49_RS16430 67b2f67cbe35265c12de13b8275fec2d 480 Gene3D G3DSA:2.40.180.10 1 357 5.3E-159 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MC49_RS16430 67b2f67cbe35265c12de13b8275fec2d 480 PRINTS PR00067 Catalase signature 83 101 1.0E-71 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MC49_RS16430 67b2f67cbe35265c12de13b8275fec2d 480 PRINTS PR00067 Catalase signature 123 141 1.0E-71 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MC49_RS16430 67b2f67cbe35265c12de13b8275fec2d 480 PRINTS PR00067 Catalase signature 288 315 1.0E-71 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MC49_RS16430 67b2f67cbe35265c12de13b8275fec2d 480 PRINTS PR00067 Catalase signature 320 346 1.0E-71 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MC49_RS16430 67b2f67cbe35265c12de13b8275fec2d 480 PRINTS PR00067 Catalase signature 20 43 1.0E-71 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MC49_RS16430 67b2f67cbe35265c12de13b8275fec2d 480 PRINTS PR00067 Catalase signature 104 121 1.0E-71 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MC49_RS16430 67b2f67cbe35265c12de13b8275fec2d 480 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 333 341 - T 29-03-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MC49_RS16430 67b2f67cbe35265c12de13b8275fec2d 480 Pfam PF06628 Catalase-related immune-responsive 415 474 8.9E-18 T 29-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MC49_RS16430 67b2f67cbe35265c12de13b8275fec2d 480 ProSitePatterns PS00438 Catalase proximal active site signature. 43 59 - T 29-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MC49_RS16430 67b2f67cbe35265c12de13b8275fec2d 480 Pfam PF00199 Catalase 7 387 8.4E-189 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 MC49_RS08840 bb8c064863f89533cc815bab8ad586cf 302 SUPERFAMILY SSF103481 39 139 1.44E-10 T 29-03-2018 MC49_RS08840 bb8c064863f89533cc815bab8ad586cf 302 Pfam PF00892 EamA-like transporter family 5 138 3.0E-13 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MC49_RS08840 bb8c064863f89533cc815bab8ad586cf 302 SUPERFAMILY SSF103481 180 282 7.45E-7 T 29-03-2018 MC49_RS08840 bb8c064863f89533cc815bab8ad586cf 302 TIGRFAM TIGR00688 rarD: protein RarD 6 257 9.5E-49 T 29-03-2018 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 MC49_RS13895 2737516c611aac393bce9665c261f86c 89 Pfam PF10762 Protein of unknown function (DUF2583) 1 87 7.0E-37 T 29-03-2018 IPR019698 Protein of unknown function DUF2583 MC49_RS03030 d975a6500488d913bb638a456911309b 166 SUPERFAMILY SSF49401 16 165 4.97E-25 T 29-03-2018 IPR008966 Adhesion domain MC49_RS03030 d975a6500488d913bb638a456911309b 166 Gene3D G3DSA:2.60.40.1090 15 165 2.6E-22 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS03030 d975a6500488d913bb638a456911309b 166 Pfam PF00419 Fimbrial protein 26 165 1.7E-9 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS01745 cb6cf038d39005498345ec4378f59e36 521 SMART SM00304 212 264 1.5E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MC49_RS01745 cb6cf038d39005498345ec4378f59e36 521 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 363 390 1.1E-54 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS01745 cb6cf038d39005498345ec4378f59e36 521 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 286 315 1.1E-54 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS01745 cb6cf038d39005498345ec4378f59e36 521 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 6 31 1.1E-54 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS01745 cb6cf038d39005498345ec4378f59e36 521 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 440 469 1.1E-54 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS01745 cb6cf038d39005498345ec4378f59e36 521 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 392 421 1.1E-54 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS01745 cb6cf038d39005498345ec4378f59e36 521 Gene3D G3DSA:1.20.120.30 24 186 2.8E-12 T 29-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain MC49_RS01745 cb6cf038d39005498345ec4378f59e36 521 SUPERFAMILY SSF58104 232 513 3.27E-67 T 29-03-2018 MC49_RS01745 cb6cf038d39005498345ec4378f59e36 521 SMART SM00283 265 512 1.0E-76 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MC49_RS01745 cb6cf038d39005498345ec4378f59e36 521 Gene3D G3DSA:1.10.287.1060 241 327 0.13 T 29-03-2018 MC49_RS01745 cb6cf038d39005498345ec4378f59e36 521 Pfam PF00672 HAMP domain 213 261 2.6E-6 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MC49_RS01745 cb6cf038d39005498345ec4378f59e36 521 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 327 478 2.1E-44 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MC49_RS01745 cb6cf038d39005498345ec4378f59e36 521 Pfam PF12729 Four helix bundle sensory module for signal transduction 6 184 8.8E-18 T 29-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain MC49_RS01745 cb6cf038d39005498345ec4378f59e36 521 Gene3D G3DSA:1.10.287.950 328 516 1.7E-44 T 29-03-2018 MC49_RS00485 4e64ebd9149c77e9d8d7b02d75c21d96 228 SMART SM00382 35 221 1.6E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS00485 4e64ebd9149c77e9d8d7b02d75c21d96 228 SUPERFAMILY SSF52540 6 226 1.11E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS00485 4e64ebd9149c77e9d8d7b02d75c21d96 228 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS00485 4e64ebd9149c77e9d8d7b02d75c21d96 228 Gene3D G3DSA:3.40.50.300 2 228 5.8E-59 T 29-03-2018 MC49_RS00485 4e64ebd9149c77e9d8d7b02d75c21d96 228 Pfam PF00005 ABC transporter 29 174 7.5E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS15820 8dd30003007af9dcfc5bf8941e85b074 126 TIGRFAM TIGR01997 sufA_proteo: FeS assembly scaffold SufA 21 126 9.6E-43 T 29-03-2018 IPR011298 FeS assembly scaffold SufA GO:0097428 MC49_RS15820 8dd30003007af9dcfc5bf8941e85b074 126 Pfam PF01521 Iron-sulphur cluster biosynthesis 22 122 1.1E-18 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MC49_RS15820 8dd30003007af9dcfc5bf8941e85b074 126 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 107 124 - T 29-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 MC49_RS15820 8dd30003007af9dcfc5bf8941e85b074 126 SUPERFAMILY SSF89360 22 115 4.58E-27 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MC49_RS15820 8dd30003007af9dcfc5bf8941e85b074 126 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 22 125 2.1E-31 T 29-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 MC49_RS15820 8dd30003007af9dcfc5bf8941e85b074 126 Gene3D G3DSA:2.60.300.12 21 126 2.3E-31 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MC49_RS11235 6b5e6deb72ec150053ed11037293a600 404 Gene3D G3DSA:3.20.140.10 1 403 2.3E-107 T 29-03-2018 MC49_RS11235 6b5e6deb72ec150053ed11037293a600 404 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 172 398 3.7E-82 T 29-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 MC49_RS11235 6b5e6deb72ec150053ed11037293a600 404 SUPERFAMILY SSF51690 121 397 9.81E-87 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 MC49_RS11235 6b5e6deb72ec150053ed11037293a600 404 SUPERFAMILY SSF54675 4 137 1.62E-41 T 29-03-2018 MC49_RS11235 6b5e6deb72ec150053ed11037293a600 404 TIGRFAM TIGR01514 NAPRTase: nicotinate phosphoribosyltransferase 8 398 3.3E-159 T 29-03-2018 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 MC49_RS11235 6b5e6deb72ec150053ed11037293a600 404 Hamap MF_00570 Nicotinate phosphoribosyltransferase [pncB]. 5 399 47.713 T 29-03-2018 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 MC49_RS11235 6b5e6deb72ec150053ed11037293a600 404 PIRSF PIRSF000484 1 382 2.8E-61 T 29-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 MC49_RS10590 05f217247b9f3bb3948d0f25411ac025 227 Pfam PF13500 AAA domain 7 213 8.8E-33 T 29-03-2018 MC49_RS10590 05f217247b9f3bb3948d0f25411ac025 227 SUPERFAMILY SSF52540 4 219 1.26E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS10590 05f217247b9f3bb3948d0f25411ac025 227 PIRSF PIRSF006755 2 223 1.2E-76 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 MC49_RS10590 05f217247b9f3bb3948d0f25411ac025 227 Gene3D G3DSA:3.40.50.300 2 218 1.8E-55 T 29-03-2018 MC49_RS10590 05f217247b9f3bb3948d0f25411ac025 227 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 3 213 27.816 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 MC49_RS10590 05f217247b9f3bb3948d0f25411ac025 227 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 7 177 5.8E-54 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 MC49_RS10020 b63db00c9bb1314aeb37fb139b148441 408 SUPERFAMILY SSF103473 13 396 1.24E-58 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS10020 b63db00c9bb1314aeb37fb139b148441 408 Gene3D G3DSA:1.20.1250.20 10 197 3.3E-27 T 29-03-2018 MC49_RS10020 b63db00c9bb1314aeb37fb139b148441 408 Pfam PF07690 Major Facilitator Superfamily 20 275 9.4E-30 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS10020 b63db00c9bb1314aeb37fb139b148441 408 Gene3D G3DSA:1.20.1250.20 201 401 2.0E-19 T 29-03-2018 MC49_RS18545 d662f0b3e127254d96aaf2a09ef20cd4 254 SMART SM00895 99 227 1.2E-13 T 29-03-2018 IPR011711 GntR, C-terminal MC49_RS18545 d662f0b3e127254d96aaf2a09ef20cd4 254 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 1.5E-24 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MC49_RS18545 d662f0b3e127254d96aaf2a09ef20cd4 254 SUPERFAMILY SSF48008 95 235 4.97E-18 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MC49_RS18545 d662f0b3e127254d96aaf2a09ef20cd4 254 SUPERFAMILY SSF46785 6 76 8.49E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS18545 d662f0b3e127254d96aaf2a09ef20cd4 254 Pfam PF07729 FCD domain 99 226 3.0E-16 T 29-03-2018 IPR011711 GntR, C-terminal MC49_RS18545 d662f0b3e127254d96aaf2a09ef20cd4 254 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 7.3E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MC49_RS18545 d662f0b3e127254d96aaf2a09ef20cd4 254 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 7.3E-11 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MC49_RS18545 d662f0b3e127254d96aaf2a09ef20cd4 254 Gene3D G3DSA:1.10.10.10 2 76 8.4E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS18545 d662f0b3e127254d96aaf2a09ef20cd4 254 SMART SM00345 15 74 7.2E-28 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MC49_RS18545 d662f0b3e127254d96aaf2a09ef20cd4 254 Gene3D G3DSA:1.20.120.530 79 245 1.3E-19 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MC49_RS05835 3a93c84f9318a7a6e3e01b38d6f83b16 508 Gene3D G3DSA:3.30.420.40 7 256 1.6E-85 T 29-03-2018 MC49_RS05835 3a93c84f9318a7a6e3e01b38d6f83b16 508 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 12 260 2.1E-89 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 MC49_RS05835 3a93c84f9318a7a6e3e01b38d6f83b16 508 Gene3D G3DSA:3.30.420.40 257 508 2.6E-78 T 29-03-2018 MC49_RS05835 3a93c84f9318a7a6e3e01b38d6f83b16 508 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 11 504 1.7E-229 T 29-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 MC49_RS05835 3a93c84f9318a7a6e3e01b38d6f83b16 508 PIRSF PIRSF000538 10 508 3.6E-178 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MC49_RS05835 3a93c84f9318a7a6e3e01b38d6f83b16 508 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 143 155 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MC49_RS05835 3a93c84f9318a7a6e3e01b38d6f83b16 508 SUPERFAMILY SSF53067 11 263 4.53E-94 T 29-03-2018 MC49_RS05835 3a93c84f9318a7a6e3e01b38d6f83b16 508 Hamap MF_00186 Glycerol kinase [glpK]. 10 505 59.497 T 29-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 MC49_RS05835 3a93c84f9318a7a6e3e01b38d6f83b16 508 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 370 390 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MC49_RS05835 3a93c84f9318a7a6e3e01b38d6f83b16 508 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 269 458 2.1E-61 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 MC49_RS05835 3a93c84f9318a7a6e3e01b38d6f83b16 508 SUPERFAMILY SSF53067 262 504 5.83E-85 T 29-03-2018 MC49_RS10355 0ae6aa338c44fc72b63d2e140af98e06 129 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 6 123 6.2E-29 T 29-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MC49_RS10355 0ae6aa338c44fc72b63d2e140af98e06 129 ProSitePatterns PS01000 Succinate dehydrogenase cytochrome b subunit signature 1. 9 33 - T 29-03-2018 IPR018495 Succinate dehydrogenase, cytochrome b subunit, conserved site GO:0000104|GO:0006099|GO:0009055|GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MC49_RS10355 0ae6aa338c44fc72b63d2e140af98e06 129 SUPERFAMILY SSF81343 4 129 3.27E-33 T 29-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MC49_RS10355 0ae6aa338c44fc72b63d2e140af98e06 129 Gene3D G3DSA:1.20.1300.10 3 129 1.3E-25 T 29-03-2018 MC49_RS10355 0ae6aa338c44fc72b63d2e140af98e06 129 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 7 126 9.1E-39 T 29-03-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MC49_RS10355 0ae6aa338c44fc72b63d2e140af98e06 129 PIRSF PIRSF000178 2 129 9.4E-30 T 29-03-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MC49_RS10355 0ae6aa338c44fc72b63d2e140af98e06 129 ProSitePatterns PS01001 Succinate dehydrogenase cytochrome b subunit signature 2. 84 97 - T 29-03-2018 IPR018495 Succinate dehydrogenase, cytochrome b subunit, conserved site GO:0000104|GO:0006099|GO:0009055|GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MC49_RS06355 2a5594de9dea14a5e99752d051bd3f18 233 Pfam PF08348 YheO-like PAS domain 28 136 2.3E-37 T 29-03-2018 IPR013559 YheO-like MC49_RS06355 2a5594de9dea14a5e99752d051bd3f18 233 Pfam PF13309 HTH domain 170 227 1.2E-18 T 29-03-2018 MC49_RS06355 2a5594de9dea14a5e99752d051bd3f18 233 ProDom PD037769 DNA-BINDING YHEO UNCHARACTERIZED BACTERIA SIMILAR HI0575 CONTAINING TRANSCRIPTION REGULATOR HELIX-TURN-HELIX 25 140 7.0E-56 T 29-03-2018 IPR013559 YheO-like MC49_RS03705 46ec1593d70267f7385e5594df3d556b 238 Pfam PF13419 Haloacid dehalogenase-like hydrolase 15 207 5.5E-12 T 29-03-2018 IPR023214 HAD-like domain MC49_RS03705 46ec1593d70267f7385e5594df3d556b 238 SUPERFAMILY SSF56784 10 238 1.41E-37 T 29-03-2018 IPR023214 HAD-like domain MC49_RS03705 46ec1593d70267f7385e5594df3d556b 238 Gene3D G3DSA:3.40.50.1000 5 227 9.6E-24 T 29-03-2018 IPR023214 HAD-like domain MC49_RS03705 46ec1593d70267f7385e5594df3d556b 238 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 115 200 1.6E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MC49_RS09050 66e2f31e491d672e9980a27c567bdbb8 816 Gene3D G3DSA:3.40.50.300 3 162 6.3E-25 T 29-03-2018 MC49_RS09050 66e2f31e491d672e9980a27c567bdbb8 816 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 5 814 1.4E-304 T 29-03-2018 IPR010225 ATP-dependent helicase HrpB GO:0008026 MC49_RS09050 66e2f31e491d672e9980a27c567bdbb8 816 Pfam PF00270 DEAD/DEAH box helicase 20 162 1.9E-11 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MC49_RS09050 66e2f31e491d672e9980a27c567bdbb8 816 SMART SM00490 226 328 1.6E-14 T 29-03-2018 IPR001650 Helicase, C-terminal MC49_RS09050 66e2f31e491d672e9980a27c567bdbb8 816 SUPERFAMILY SSF52540 16 337 2.39E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS09050 66e2f31e491d672e9980a27c567bdbb8 816 Pfam PF08482 ATP-dependent helicase C-terminal 671 803 8.6E-55 T 29-03-2018 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal MC49_RS09050 66e2f31e491d672e9980a27c567bdbb8 816 Pfam PF04408 Helicase associated domain (HA2) 389 447 1.9E-5 T 29-03-2018 IPR007502 Helicase-associated domain GO:0004386 MC49_RS09050 66e2f31e491d672e9980a27c567bdbb8 816 Pfam PF00271 Helicase conserved C-terminal domain 203 327 4.0E-13 T 29-03-2018 IPR001650 Helicase, C-terminal MC49_RS09050 66e2f31e491d672e9980a27c567bdbb8 816 PIRSF PIRSF005496 2 816 2.8E-294 T 29-03-2018 MC49_RS09050 66e2f31e491d672e9980a27c567bdbb8 816 SMART SM00487 5 186 1.2E-18 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MC49_RS09050 66e2f31e491d672e9980a27c567bdbb8 816 Gene3D G3DSA:3.40.50.300 180 349 4.2E-44 T 29-03-2018 MC49_RS07970 27e5d86bd03febefe8d6dace84cb1a32 255 SUPERFAMILY SSF47807 159 243 7.33E-21 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 MC49_RS07970 27e5d86bd03febefe8d6dace84cb1a32 255 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 3 150 8.1E-31 T 29-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 MC49_RS07970 27e5d86bd03febefe8d6dace84cb1a32 255 Hamap MF_01192 Flap endonuclease Xni [xni]. 1 250 41.961 T 29-03-2018 IPR022895 Flap endonuclease Xni GO:0048256 MC49_RS07970 27e5d86bd03febefe8d6dace84cb1a32 255 Gene3D G3DSA:1.10.150.20 173 250 8.6E-20 T 29-03-2018 MC49_RS07970 27e5d86bd03febefe8d6dace84cb1a32 255 SUPERFAMILY SSF88723 3 158 7.85E-39 T 29-03-2018 IPR029060 PIN domain-like MC49_RS07970 27e5d86bd03febefe8d6dace84cb1a32 255 Gene3D G3DSA:3.40.50.1010 2 172 1.6E-40 T 29-03-2018 IPR029060 PIN domain-like MC49_RS07970 27e5d86bd03febefe8d6dace84cb1a32 255 SMART SM00475 2 249 6.2E-74 T 29-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 MC49_RS07970 27e5d86bd03febefe8d6dace84cb1a32 255 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 159 248 5.3E-22 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 MC49_RS07970 27e5d86bd03febefe8d6dace84cb1a32 255 SMART SM00279 161 196 6.2E-9 T 29-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 MC49_RS01970 524da1146d18c79f40b98fe6dc2a80f6 535 Gene3D G3DSA:1.10.10.60 451 521 7.7E-9 T 29-03-2018 MC49_RS01970 524da1146d18c79f40b98fe6dc2a80f6 535 SMART SM00382 227 371 2.9E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS01970 524da1146d18c79f40b98fe6dc2a80f6 535 SMART SM00065 32 181 7.3E-13 T 29-03-2018 IPR003018 GAF domain GO:0005515 MC49_RS01970 524da1146d18c79f40b98fe6dc2a80f6 535 SUPERFAMILY SSF55781 13 185 4.36E-18 T 29-03-2018 IPR029016 GAF domain-like MC49_RS01970 524da1146d18c79f40b98fe6dc2a80f6 535 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 485 502 2.8E-5 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MC49_RS01970 524da1146d18c79f40b98fe6dc2a80f6 535 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 505 525 2.8E-5 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MC49_RS01970 524da1146d18c79f40b98fe6dc2a80f6 535 Gene3D G3DSA:1.10.8.60 379 450 9.8E-25 T 29-03-2018 MC49_RS01970 524da1146d18c79f40b98fe6dc2a80f6 535 SUPERFAMILY SSF52540 206 444 6.07E-75 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS01970 524da1146d18c79f40b98fe6dc2a80f6 535 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 231 244 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MC49_RS01970 524da1146d18c79f40b98fe6dc2a80f6 535 Pfam PF01590 GAF domain 33 171 2.8E-9 T 29-03-2018 IPR003018 GAF domain GO:0005515 MC49_RS01970 524da1146d18c79f40b98fe6dc2a80f6 535 Pfam PF00158 Sigma-54 interaction domain 207 373 2.7E-70 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MC49_RS01970 524da1146d18c79f40b98fe6dc2a80f6 535 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 420 429 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site MC49_RS01970 524da1146d18c79f40b98fe6dc2a80f6 535 SUPERFAMILY SSF46689 420 524 9.86E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS01970 524da1146d18c79f40b98fe6dc2a80f6 535 Pfam PF02954 Bacterial regulatory protein, Fis family 481 522 1.0E-5 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MC49_RS01970 524da1146d18c79f40b98fe6dc2a80f6 535 Gene3D G3DSA:3.40.50.300 212 378 7.6E-31 T 29-03-2018 MC49_RS01970 524da1146d18c79f40b98fe6dc2a80f6 535 Gene3D G3DSA:3.30.450.40 3 211 1.8E-24 T 29-03-2018 IPR029016 GAF domain-like MC49_RS02655 b43d9c025eeb283232ad82b092764daa 385 Gene3D G3DSA:3.90.1150.10 261 385 3.3E-32 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS02655 b43d9c025eeb283232ad82b092764daa 385 Gene3D G3DSA:3.40.640.10 7 259 3.8E-57 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS02655 b43d9c025eeb283232ad82b092764daa 385 PIRSF PIRSF001434 2 384 2.8E-122 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MC49_RS02655 b43d9c025eeb283232ad82b092764daa 385 SUPERFAMILY SSF53383 28 383 1.14E-95 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS02655 b43d9c025eeb283232ad82b092764daa 385 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 200 214 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MC49_RS02655 b43d9c025eeb283232ad82b092764daa 385 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 10 380 9.0E-116 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MC49_RS16905 c53ea3bb64e413d2a6a0f7bcb0f13250 282 Gene3D G3DSA:3.40.50.720 1 282 3.9E-23 T 29-03-2018 MC49_RS16905 c53ea3bb64e413d2a6a0f7bcb0f13250 282 SUPERFAMILY SSF51735 2 245 7.08E-59 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS16905 c53ea3bb64e413d2a6a0f7bcb0f13250 282 Pfam PF05368 NmrA-like family 2 220 1.8E-21 T 29-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 MC49_RS00095 3c3c70d35f1ea260a61bbdd96b02b9c8 72 SUPERFAMILY SSF46575 2 68 1.57E-26 T 29-03-2018 MC49_RS00095 3c3c70d35f1ea260a61bbdd96b02b9c8 72 ProDom PD057609 DNA POLYMERASE THETA SUBUNIT TRANSFERASE III NUCLEOTIDYLTRANSFERASE III DNA-DIRECTED REPLICATION 3 67 5.0E-15 T 29-03-2018 IPR009052 DNA polymerase III-theta, bacterial GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS00095 3c3c70d35f1ea260a61bbdd96b02b9c8 72 Pfam PF06440 DNA polymerase III, theta subunit 2 67 1.1E-26 T 29-03-2018 IPR009052 DNA polymerase III-theta, bacterial GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS00095 3c3c70d35f1ea260a61bbdd96b02b9c8 72 Gene3D G3DSA:1.20.58.250 2 64 4.4E-29 T 29-03-2018 IPR009052 DNA polymerase III-theta, bacterial GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS04435 a712322ffceea939dd9e1beb57c62994 210 Pfam PF01810 LysE type translocator 17 207 4.1E-27 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MC49_RS04435 a712322ffceea939dd9e1beb57c62994 210 PIRSF PIRSF006324 1 209 4.9E-43 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MC49_RS09130 0e51b6f0d4e8e50a8a3ae9128efea711 228 Gene3D G3DSA:1.10.3480.10 2 228 3.5E-47 T 29-03-2018 IPR020945 DMSO/Nitrate reductase chaperone MC49_RS09130 0e51b6f0d4e8e50a8a3ae9128efea711 228 Pfam PF02613 Nitrate reductase delta subunit 52 191 1.1E-33 T 29-03-2018 IPR020945 DMSO/Nitrate reductase chaperone MC49_RS09130 0e51b6f0d4e8e50a8a3ae9128efea711 228 SUPERFAMILY SSF89155 9 221 1.31E-44 T 29-03-2018 IPR020945 DMSO/Nitrate reductase chaperone MC49_RS03795 ea397c00bafff3286c3cf307eff3e91b 417 Pfam PF01943 Polysaccharide biosynthesis protein 4 285 6.1E-10 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 MC49_RS03795 ea397c00bafff3286c3cf307eff3e91b 417 Hamap MF_02024 Lipid III flippase [wzxE]. 1 417 39.829 T 29-03-2018 IPR032896 Lipid III flippase WzxE GO:0005886|GO:0009246 MC49_RS08880 fdc7e67cf2a3928006726f87bafaa4e0 297 SUPERFAMILY SSF51735 2 135 5.34E-21 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS08880 fdc7e67cf2a3928006726f87bafaa4e0 297 Gene3D G3DSA:3.40.50.720 1 133 7.9E-15 T 29-03-2018 MC49_RS08880 fdc7e67cf2a3928006726f87bafaa4e0 297 PIRSF PIRSF025648 1 297 2.3E-114 T 29-03-2018 IPR010190 Diaminopimelate dehydrogenase, Ddh GO:0009089|GO:0047850 KEGG: 00300+1.4.1.16|MetaCyc: PWY-2942 MC49_RS08880 fdc7e67cf2a3928006726f87bafaa4e0 297 TIGRFAM TIGR01921 DAP-DH: diaminopimelate dehydrogenase 2 297 1.2E-100 T 29-03-2018 IPR010190 Diaminopimelate dehydrogenase, Ddh GO:0009089|GO:0047850 KEGG: 00300+1.4.1.16|MetaCyc: PWY-2942 MC49_RS08880 fdc7e67cf2a3928006726f87bafaa4e0 297 SUPERFAMILY SSF55347 119 250 9.81E-48 T 29-03-2018 MC49_RS08880 fdc7e67cf2a3928006726f87bafaa4e0 297 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 84 6.2E-6 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 MC49_RS08880 fdc7e67cf2a3928006726f87bafaa4e0 297 Pfam PF16654 Diaminopimelic acid dehydrogenase C-terminal domain 118 174 2.8E-13 T 29-03-2018 IPR032094 Meso-diaminopimelate D-dehydrogenase, C-terminal KEGG: 00300+1.4.1.16|MetaCyc: PWY-2942 MC49_RS08880 fdc7e67cf2a3928006726f87bafaa4e0 297 Gene3D G3DSA:3.30.360.10 134 245 3.1E-39 T 29-03-2018 MC49_RS13225 362ff98e85423d0b94e139f742ec9a7c 402 SUPERFAMILY SSF53098 1 376 2.73E-70 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MC49_RS13225 362ff98e85423d0b94e139f742ec9a7c 402 Gene3D G3DSA:3.90.350.10 50 313 6.3E-21 T 29-03-2018 IPR014736 Transposase, Tn5-like, core MC49_RS13225 362ff98e85423d0b94e139f742ec9a7c 402 Pfam PF01609 Transposase DDE domain 91 327 1.2E-26 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MC49_RS04955 362ff98e85423d0b94e139f742ec9a7c 402 SUPERFAMILY SSF53098 1 376 2.73E-70 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MC49_RS04955 362ff98e85423d0b94e139f742ec9a7c 402 Gene3D G3DSA:3.90.350.10 50 313 6.3E-21 T 29-03-2018 IPR014736 Transposase, Tn5-like, core MC49_RS04955 362ff98e85423d0b94e139f742ec9a7c 402 Pfam PF01609 Transposase DDE domain 91 327 1.2E-26 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MC49_RS07075 ea9d5904ece1805d0b6e04db7708315c 378 Pfam PF01139 tRNA-splicing ligase RtcB 29 101 3.4E-12 T 29-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 MC49_RS07075 ea9d5904ece1805d0b6e04db7708315c 378 Pfam PF01139 tRNA-splicing ligase RtcB 97 372 2.6E-60 T 29-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 MC49_RS07075 ea9d5904ece1805d0b6e04db7708315c 378 TIGRFAM TIGR03073 release_rtcB: release factor H-coupled RctB family protein 12 367 5.0E-174 T 29-03-2018 IPR017510 Release factor H-coupled RctB family protein MC49_RS07075 ea9d5904ece1805d0b6e04db7708315c 378 SUPERFAMILY SSF103365 5 372 7.72E-103 T 29-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 MC49_RS15600 6fe781e75a8a107ac608efb775dbe7cb 224 Gene3D G3DSA:1.10.287.510 29 154 0.0015 T 29-03-2018 MC49_RS15600 6fe781e75a8a107ac608efb775dbe7cb 224 TIGRFAM TIGR02977 phageshock_pspA: phage shock protein A 1 218 5.5E-90 T 29-03-2018 IPR014319 Phage shock protein, PspA MC49_RS15600 6fe781e75a8a107ac608efb775dbe7cb 224 Gene3D G3DSA:1.20.5.1070 155 224 6.3E-4 T 29-03-2018 MC49_RS15600 6fe781e75a8a107ac608efb775dbe7cb 224 Pfam PF04012 PspA/IM30 family 2 219 1.4E-45 T 29-03-2018 IPR007157 PspA/IM30 MC49_RS17095 84cb48f8b25061ded3f099ca1582177a 244 SUPERFAMILY SSF51735 4 243 1.81E-87 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS17095 84cb48f8b25061ded3f099ca1582177a 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 2.9E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS17095 84cb48f8b25061ded3f099ca1582177a 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 2.9E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS17095 84cb48f8b25061ded3f099ca1582177a 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 2.9E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS17095 84cb48f8b25061ded3f099ca1582177a 244 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MC49_RS17095 84cb48f8b25061ded3f099ca1582177a 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 241 2.7E-68 T 29-03-2018 MC49_RS17095 84cb48f8b25061ded3f099ca1582177a 244 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 8 242 2.9E-103 T 29-03-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MC49_RS17095 84cb48f8b25061ded3f099ca1582177a 244 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 187 8.8E-6 T 29-03-2018 MC49_RS17095 84cb48f8b25061ded3f099ca1582177a 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 3.6E-50 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS17095 84cb48f8b25061ded3f099ca1582177a 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 3.6E-50 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS17095 84cb48f8b25061ded3f099ca1582177a 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 3.6E-50 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS17095 84cb48f8b25061ded3f099ca1582177a 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 3.6E-50 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS17095 84cb48f8b25061ded3f099ca1582177a 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 3.6E-50 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS17095 84cb48f8b25061ded3f099ca1582177a 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 3.6E-50 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS17095 84cb48f8b25061ded3f099ca1582177a 244 Gene3D G3DSA:3.40.50.720 49 244 2.2E-66 T 29-03-2018 MC49_RS17095 84cb48f8b25061ded3f099ca1582177a 244 Gene3D G3DSA:3.40.50.720 1 48 2.9E-11 T 29-03-2018 MC49_RS18755 3dde7332c6d2915c66f602bf80a60a8c 228 Pfam PF02976 DNA mismatch repair enzyme MutH 59 157 3.6E-32 T 29-03-2018 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 MC49_RS18755 3dde7332c6d2915c66f602bf80a60a8c 228 SUPERFAMILY SSF52980 8 226 2.25E-80 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MC49_RS18755 3dde7332c6d2915c66f602bf80a60a8c 228 Hamap MF_00759 DNA mismatch repair protein MutH [mutH]. 1 228 152.667 T 29-03-2018 IPR004230 DNA mismatch repair protein MutH GO:0003677|GO:0004519|GO:0006304 MC49_RS18755 3dde7332c6d2915c66f602bf80a60a8c 228 TIGRFAM TIGR02248 mutH_TIGR: DNA mismatch repair endonuclease MutH 11 225 2.9E-108 T 29-03-2018 IPR004230 DNA mismatch repair protein MutH GO:0003677|GO:0004519|GO:0006304 MC49_RS18755 3dde7332c6d2915c66f602bf80a60a8c 228 Gene3D G3DSA:3.40.600.10 9 228 3.5E-55 T 29-03-2018 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 MC49_RS18755 3dde7332c6d2915c66f602bf80a60a8c 228 SMART SM00927 59 157 1.3E-62 T 29-03-2018 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 MC49_RS14935 883640d051f1c3d6d1756ce27c5f2ebe 168 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 57 141 7.0E-13 T 29-03-2018 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 MC49_RS14935 883640d051f1c3d6d1756ce27c5f2ebe 168 Gene3D G3DSA:3.90.1590.10 26 164 9.8E-29 T 29-03-2018 MC49_RS14935 883640d051f1c3d6d1756ce27c5f2ebe 168 SUPERFAMILY SSF51316 32 158 4.39E-39 T 29-03-2018 IPR011057 Mss4-like MC49_RS07160 63741a4864531752993d8a993a3cf18b 444 Gene3D G3DSA:3.40.350.10 4 150 0.0054 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal MC49_RS07160 63741a4864531752993d8a993a3cf18b 444 SUPERFAMILY SSF55920 164 439 1.83E-53 T 29-03-2018 IPR000994 Peptidase M24 MC49_RS07160 63741a4864531752993d8a993a3cf18b 444 Gene3D G3DSA:3.90.230.10 151 441 1.1E-48 T 29-03-2018 MC49_RS07160 63741a4864531752993d8a993a3cf18b 444 Hamap MF_01279 Xaa-Pro dipeptidase [pepQ]. 1 444 56.076 T 29-03-2018 IPR022846 Xaa-Pro dipeptidase GO:0016795 MC49_RS07160 63741a4864531752993d8a993a3cf18b 444 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 336 348 - T 29-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site MC49_RS07160 63741a4864531752993d8a993a3cf18b 444 Pfam PF00557 Metallopeptidase family M24 169 431 2.1E-41 T 29-03-2018 IPR000994 Peptidase M24 MC49_RS02145 9d9e0efcb309632e56d5315325e871cb 190 Gene3D G3DSA:1.10.357.10 43 179 1.9E-14 T 29-03-2018 MC49_RS02145 9d9e0efcb309632e56d5315325e871cb 190 SUPERFAMILY SSF48498 75 178 1.04E-7 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MC49_RS07675 b9a6c8d6a794b41006551d2683cf8554 393 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 149 212 2.7E-14 T 29-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 MC49_RS07675 b9a6c8d6a794b41006551d2683cf8554 393 SUPERFAMILY SSF81891 120 383 6.93E-44 T 29-03-2018 MC49_RS07675 b9a6c8d6a794b41006551d2683cf8554 393 PIRSF PIRSF000813 1 391 5.3E-154 T 29-03-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 MC49_RS07675 b9a6c8d6a794b41006551d2683cf8554 393 Gene3D G3DSA:1.10.3090.10 119 392 4.9E-40 T 29-03-2018 MC49_RS07675 b9a6c8d6a794b41006551d2683cf8554 393 Pfam PF01743 Poly A polymerase head domain 3 122 5.3E-18 T 29-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 MC49_RS07675 b9a6c8d6a794b41006551d2683cf8554 393 SUPERFAMILY SSF81301 2 119 6.65E-31 T 29-03-2018 MC49_RS07675 b9a6c8d6a794b41006551d2683cf8554 393 Gene3D G3DSA:3.30.460.10 1 118 4.2E-29 T 29-03-2018 MC49_RS07675 b9a6c8d6a794b41006551d2683cf8554 393 Hamap MF_01262 CCA-adding enzyme [cca]. 1 384 44.185 T 29-03-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 MC49_RS05880 ea555f8300811499e1b611a7d33593aa 738 Gene3D G3DSA:3.40.50.300 202 368 4.8E-26 T 29-03-2018 MC49_RS05880 ea555f8300811499e1b611a7d33593aa 738 Gene3D G3DSA:3.40.50.300 404 627 1.3E-21 T 29-03-2018 MC49_RS05880 ea555f8300811499e1b611a7d33593aa 738 TIGRFAM TIGR00595 priA: primosomal protein N' 227 735 1.7E-204 T 29-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 MC49_RS05880 ea555f8300811499e1b611a7d33593aa 738 Pfam PF00270 DEAD/DEAH box helicase 227 368 7.3E-13 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MC49_RS05880 ea555f8300811499e1b611a7d33593aa 738 SMART SM00487 201 386 3.6E-16 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MC49_RS05880 ea555f8300811499e1b611a7d33593aa 738 Hamap MF_00983 Probable primosomal protein N' [priA]. 11 738 25.337 T 29-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 MC49_RS05880 ea555f8300811499e1b611a7d33593aa 738 SMART SM00490 498 595 4.0E-9 T 29-03-2018 IPR001650 Helicase, C-terminal MC49_RS05880 ea555f8300811499e1b611a7d33593aa 738 Pfam PF00271 Helicase conserved C-terminal domain 526 595 1.6E-5 T 29-03-2018 IPR001650 Helicase, C-terminal MC49_RS05880 ea555f8300811499e1b611a7d33593aa 738 SUPERFAMILY SSF52540 222 446 1.11E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS05880 ea555f8300811499e1b611a7d33593aa 738 SUPERFAMILY SSF52540 509 607 1.11E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS08470 7e474b4e8cae35a1938fc5992d718110 286 Pfam PF00288 GHMP kinases N terminal domain 72 120 4.7E-10 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 MC49_RS08470 7e474b4e8cae35a1938fc5992d718110 286 PIRSF PIRSF033887 1 279 1.7E-64 T 29-03-2018 IPR012363 Propanediol utilisation/coumermycin biosynthesis, PduX-related KEGG: 00040+2.7.1.17|KEGG: 00860+2.7.1.177|MetaCyc: PWY-5443 MC49_RS08470 7e474b4e8cae35a1938fc5992d718110 286 SUPERFAMILY SSF54211 3 136 1.21E-21 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MC49_RS08470 7e474b4e8cae35a1938fc5992d718110 286 Gene3D G3DSA:3.30.230.10 35 143 5.4E-15 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MC49_RS07805 ce37981932e8fb80cbb6a0287fe592b4 789 Pfam PF03968 OstA-like protein 54 192 2.2E-19 T 29-03-2018 IPR005653 Organic solvent tolerance-like, N-terminal MC49_RS07805 ce37981932e8fb80cbb6a0287fe592b4 789 Pfam PF04453 Organic solvent tolerance protein 313 704 1.8E-102 T 29-03-2018 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 MC49_RS07805 ce37981932e8fb80cbb6a0287fe592b4 789 Hamap MF_01411 LPS-assembly protein LptD [lptD]. 14 768 21.164 T 29-03-2018 IPR020889 LPS-assembly protein LptD GO:0009279|GO:0010033|GO:0015920|GO:0043165 MC49_RS07805 ce37981932e8fb80cbb6a0287fe592b4 789 Gene3D G3DSA:2.60.450.10 45 207 1.3E-13 T 29-03-2018 MC49_RS12705 0c344e9790ff76e626f7d2413bac2492 362 Pfam PF00700 Bacterial flagellin C-terminal helical region 277 361 8.5E-31 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 MC49_RS12705 0c344e9790ff76e626f7d2413bac2492 362 Gene3D G3DSA:1.20.1330.10 40 334 3.2E-68 T 29-03-2018 MC49_RS12705 0c344e9790ff76e626f7d2413bac2492 362 PRINTS PR00207 Flagellin signature 37 54 2.1E-29 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 MC49_RS12705 0c344e9790ff76e626f7d2413bac2492 362 PRINTS PR00207 Flagellin signature 76 95 2.1E-29 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 MC49_RS12705 0c344e9790ff76e626f7d2413bac2492 362 PRINTS PR00207 Flagellin signature 111 134 2.1E-29 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 MC49_RS12705 0c344e9790ff76e626f7d2413bac2492 362 SUPERFAMILY SSF64518 1 362 1.83E-97 T 29-03-2018 MC49_RS12705 0c344e9790ff76e626f7d2413bac2492 362 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 140 1.2E-42 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 MC49_RS15865 4030f4490c5cd6ecf8f8787517e5e55e 276 Pfam PF01497 Periplasmic binding protein 24 248 4.1E-29 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 MC49_RS15865 4030f4490c5cd6ecf8f8787517e5e55e 276 Gene3D G3DSA:3.40.50.1980 22 126 8.1E-24 T 29-03-2018 MC49_RS15865 4030f4490c5cd6ecf8f8787517e5e55e 276 Gene3D G3DSA:3.40.50.1980 127 275 2.0E-23 T 29-03-2018 MC49_RS15865 4030f4490c5cd6ecf8f8787517e5e55e 276 SUPERFAMILY SSF53807 24 270 1.06E-46 T 29-03-2018 MC49_RS14280 9bd213be99a872bab9d566fd5429e62b 115 SUPERFAMILY SSF51182 14 107 3.45E-21 T 29-03-2018 IPR011051 RmlC-like cupin domain MC49_RS14280 9bd213be99a872bab9d566fd5429e62b 115 Gene3D G3DSA:2.60.120.10 1 109 1.3E-18 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MC49_RS14280 9bd213be99a872bab9d566fd5429e62b 115 Pfam PF07883 Cupin domain 40 105 3.0E-9 T 29-03-2018 IPR013096 Cupin 2, conserved barrel MC49_RS07725 66ade2cac1fd43b01e1a983e6003e56e 454 SUPERFAMILY SSF56954 24 440 3.79E-91 T 29-03-2018 MC49_RS07725 66ade2cac1fd43b01e1a983e6003e56e 454 Gene3D G3DSA:1.20.1600.10 10 433 6.7E-74 T 29-03-2018 MC49_RS07725 66ade2cac1fd43b01e1a983e6003e56e 454 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 21 438 5.1E-120 T 29-03-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0006810|GO:0019867 MC49_RS07725 66ade2cac1fd43b01e1a983e6003e56e 454 Pfam PF02321 Outer membrane efflux protein 232 416 6.2E-35 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MC49_RS07725 66ade2cac1fd43b01e1a983e6003e56e 454 Pfam PF02321 Outer membrane efflux protein 25 209 3.9E-26 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MC49_RS11590 c767f672aa60806cb709a61b1f26cce7 267 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 4 249 7.5E-59 T 29-03-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 MC49_RS11590 c767f672aa60806cb709a61b1f26cce7 267 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 2 248 3.0E-87 T 29-03-2018 IPR008275 CoA enzyme activase MC49_RS11590 c767f672aa60806cb709a61b1f26cce7 267 Gene3D G3DSA:3.30.420.40 1 88 3.3E-4 T 29-03-2018 MC49_RS11590 c767f672aa60806cb709a61b1f26cce7 267 SUPERFAMILY SSF53067 1 253 1.57E-35 T 29-03-2018 MC49_RS11590 c767f672aa60806cb709a61b1f26cce7 267 Gene3D G3DSA:3.30.420.40 94 235 1.6E-35 T 29-03-2018 MC49_RS06135 c2d6a79feeb57a9afefd4ea4be12083f 300 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 17 69 3.5E-16 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain MC49_RS06135 c2d6a79feeb57a9afefd4ea4be12083f 300 Gene3D G3DSA:1.10.3720.10 21 287 2.3E-48 T 29-03-2018 MC49_RS06135 c2d6a79feeb57a9afefd4ea4be12083f 300 SUPERFAMILY SSF161098 93 280 1.96E-30 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS06135 c2d6a79feeb57a9afefd4ea4be12083f 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 299 4.8E-30 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS02485 f764764308d2a4383d195a72caf1e987 418 SUPERFAMILY SSF53850 27 331 9.2E-37 T 29-03-2018 MC49_RS02485 f764764308d2a4383d195a72caf1e987 418 Gene3D G3DSA:3.40.190.10 144 292 7.6E-23 T 29-03-2018 MC49_RS02485 f764764308d2a4383d195a72caf1e987 418 Pfam PF13343 Bacterial extracellular solute-binding protein 81 303 8.5E-27 T 29-03-2018 MC49_RS02485 f764764308d2a4383d195a72caf1e987 418 Gene3D G3DSA:3.40.190.10 22 143 3.6E-4 T 29-03-2018 MC49_RS11465 46db5a4d00b69e2879407305f8ccc788 333 Pfam PF00419 Fimbrial protein 187 333 1.7E-15 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS11465 46db5a4d00b69e2879407305f8ccc788 333 Gene3D G3DSA:2.60.40.1090 197 333 1.3E-12 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS11465 46db5a4d00b69e2879407305f8ccc788 333 SUPERFAMILY SSF49401 194 333 5.97E-13 T 29-03-2018 IPR008966 Adhesion domain MC49_RS08835 005644f453339ca710ded6a417bfbd94 332 SUPERFAMILY SSF53822 68 331 3.73E-39 T 29-03-2018 IPR028082 Periplasmic binding protein-like I MC49_RS08835 005644f453339ca710ded6a417bfbd94 332 Gene3D G3DSA:3.40.50.2300 62 173 3.2E-15 T 29-03-2018 MC49_RS08835 005644f453339ca710ded6a417bfbd94 332 Gene3D G3DSA:3.40.50.2300 174 308 3.5E-22 T 29-03-2018 MC49_RS08835 005644f453339ca710ded6a417bfbd94 332 SUPERFAMILY SSF47413 1 57 4.08E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS08835 005644f453339ca710ded6a417bfbd94 332 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.1E-13 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MC49_RS08835 005644f453339ca710ded6a417bfbd94 332 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 72 326 1.1E-42 T 29-03-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain MC49_RS08835 005644f453339ca710ded6a417bfbd94 332 SMART SM00354 1 73 2.1E-16 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MC49_RS08835 005644f453339ca710ded6a417bfbd94 332 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 29-03-2018 MC49_RS08835 005644f453339ca710ded6a417bfbd94 332 Gene3D G3DSA:1.10.260.40 3 61 1.7E-15 T 29-03-2018 MC49_RS05975 66a933ff0b90e494a917130f085184cb 218 Hamap MF_01190 HTH-type transcriptional repressor FabR [fabR]. 5 213 54.097 T 29-03-2018 IPR023764 Transcriptional repressor HTH, FabR MC49_RS05975 66a933ff0b90e494a917130f085184cb 218 SUPERFAMILY SSF46689 7 81 2.84E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS05975 66a933ff0b90e494a917130f085184cb 218 Gene3D G3DSA:1.10.357.10 6 208 1.7E-25 T 29-03-2018 MC49_RS05975 66a933ff0b90e494a917130f085184cb 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 62 5.7E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS05170 810b249075919831f9070c642eb2eea0 287 SUPERFAMILY SSF52943 2 287 1.7E-95 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05170 810b249075919831f9070c642eb2eea0 287 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 273 286 - T 29-03-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05170 810b249075919831f9070c642eb2eea0 287 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 287 36.134 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05170 810b249075919831f9070c642eb2eea0 287 Pfam PF00231 ATP synthase 5 286 3.3E-96 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05170 810b249075919831f9070c642eb2eea0 287 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 287 1.4E-109 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05170 810b249075919831f9070c642eb2eea0 287 Gene3D G3DSA:3.40.1380.10 42 239 2.1E-72 T 29-03-2018 MC49_RS05170 810b249075919831f9070c642eb2eea0 287 PRINTS PR00126 ATP synthase gamma subunit signature 234 253 2.1E-37 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05170 810b249075919831f9070c642eb2eea0 287 PRINTS PR00126 ATP synthase gamma subunit signature 73 92 2.1E-37 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05170 810b249075919831f9070c642eb2eea0 287 PRINTS PR00126 ATP synthase gamma subunit signature 265 286 2.1E-37 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05170 810b249075919831f9070c642eb2eea0 287 PRINTS PR00126 ATP synthase gamma subunit signature 166 183 2.1E-37 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05170 810b249075919831f9070c642eb2eea0 287 Gene3D G3DSA:1.10.287.80 240 282 9.0E-15 T 29-03-2018 MC49_RS05170 810b249075919831f9070c642eb2eea0 287 Gene3D G3DSA:1.10.287.80 2 41 6.1E-18 T 29-03-2018 MC49_RS04385 ac1a8e9814c8ee768e45e46cde690041 75 SUPERFAMILY SSF50037 3 72 5.26E-16 T 29-03-2018 IPR008988 Transcriptional repressor, C-terminal MC49_RS04385 ac1a8e9814c8ee768e45e46cde690041 75 Pfam PF04023 FeoA domain 3 64 3.6E-8 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 MC49_RS04385 ac1a8e9814c8ee768e45e46cde690041 75 SMART SM00899 1 72 3.3E-10 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 MC49_RS04385 ac1a8e9814c8ee768e45e46cde690041 75 Gene3D G3DSA:2.30.30.90 1 75 1.4E-13 T 29-03-2018 MC49_RS06015 31a163c272e50893761f0e104d8e7822 606 Pfam PF00009 Elongation factor Tu GTP binding domain 5 196 1.9E-56 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS06015 31a163c272e50893761f0e104d8e7822 606 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 140 4.1E-24 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MC49_RS06015 31a163c272e50893761f0e104d8e7822 606 Gene3D G3DSA:2.40.50.250 484 574 4.4E-37 T 29-03-2018 MC49_RS06015 31a163c272e50893761f0e104d8e7822 606 SUPERFAMILY SSF50447 152 300 1.17E-32 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain MC49_RS06015 31a163c272e50893761f0e104d8e7822 606 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 45 60 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site MC49_RS06015 31a163c272e50893761f0e104d8e7822 606 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 6 600 4.4E-288 T 29-03-2018 IPR006298 GTP-binding protein TypA GO:0005525 MC49_RS06015 31a163c272e50893761f0e104d8e7822 606 SUPERFAMILY SSF54980 303 388 1.29E-15 T 29-03-2018 IPR035647 EF-G domain III/V-like MC49_RS06015 31a163c272e50893761f0e104d8e7822 606 Gene3D G3DSA:3.40.50.300 2 68 1.2E-10 T 29-03-2018 MC49_RS06015 31a163c272e50893761f0e104d8e7822 606 Pfam PF00679 Elongation factor G C-terminus 398 478 2.2E-21 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like MC49_RS06015 31a163c272e50893761f0e104d8e7822 606 SUPERFAMILY SSF52540 3 208 1.27E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS06015 31a163c272e50893761f0e104d8e7822 606 Gene3D G3DSA:3.40.50.300 69 187 1.3E-29 T 29-03-2018 MC49_RS06015 31a163c272e50893761f0e104d8e7822 606 Gene3D G3DSA:2.40.30.10 188 301 2.7E-21 T 29-03-2018 MC49_RS06015 31a163c272e50893761f0e104d8e7822 606 SUPERFAMILY SSF54980 399 513 6.71E-26 T 29-03-2018 IPR035647 EF-G domain III/V-like MC49_RS06015 31a163c272e50893761f0e104d8e7822 606 Pfam PF03144 Elongation factor Tu domain 2 220 290 1.7E-8 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MC49_RS06015 31a163c272e50893761f0e104d8e7822 606 PRINTS PR00315 GTP-binding elongation factor signature 52 60 3.3E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS06015 31a163c272e50893761f0e104d8e7822 606 PRINTS PR00315 GTP-binding elongation factor signature 8 21 3.3E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS06015 31a163c272e50893761f0e104d8e7822 606 PRINTS PR00315 GTP-binding elongation factor signature 72 82 3.3E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS06015 31a163c272e50893761f0e104d8e7822 606 PRINTS PR00315 GTP-binding elongation factor signature 124 133 3.3E-13 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MC49_RS06015 31a163c272e50893761f0e104d8e7822 606 Gene3D G3DSA:3.30.70.870 303 401 1.3E-31 T 29-03-2018 MC49_RS06015 31a163c272e50893761f0e104d8e7822 606 Gene3D G3DSA:3.30.70.240 402 483 8.9E-19 T 29-03-2018 MC49_RS19120 99c30516b8157c0a2b87c81199fb6498 285 PIRSF PIRSF001359 1 284 3.6E-110 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MC49_RS19120 99c30516b8157c0a2b87c81199fb6498 285 Gene3D G3DSA:3.20.20.70 1 285 1.8E-100 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS19120 99c30516b8157c0a2b87c81199fb6498 285 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 131 142 - T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MC49_RS19120 99c30516b8157c0a2b87c81199fb6498 285 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 3 283 8.8E-106 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MC49_RS19120 99c30516b8157c0a2b87c81199fb6498 285 TIGRFAM TIGR01858 tag_bisphos_ald: class II aldolase, tagatose bisphosphate family 3 283 5.4E-151 T 29-03-2018 IPR011288 D-tagatose-bisphosphate aldolase, class II, subunit KbaY/GatY GO:0005975|GO:0008270|GO:0009025 KEGG: 00052+4.1.2.40|MetaCyc: PWY-7077|MetaCyc: PWY-7395 MC49_RS19120 99c30516b8157c0a2b87c81199fb6498 285 SUPERFAMILY SSF51569 3 283 5.57E-95 T 29-03-2018 MC49_RS19120 99c30516b8157c0a2b87c81199fb6498 285 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 73 84 - T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MC49_RS19120 99c30516b8157c0a2b87c81199fb6498 285 Pfam PF01116 Fructose-bisphosphate aldolase class-II 5 283 6.2E-93 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 MC49_RS01965 c64c6c66ac0784cf1dd6c27c5af428bc 182 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 90 101 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MC49_RS01965 c64c6c66ac0784cf1dd6c27c5af428bc 182 Gene3D G3DSA:3.30.70.20 1 18 0.0086 T 29-03-2018 MC49_RS01965 c64c6c66ac0784cf1dd6c27c5af428bc 182 Pfam PF13247 4Fe-4S dicluster domain 57 158 2.3E-9 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MC49_RS01965 c64c6c66ac0784cf1dd6c27c5af428bc 182 Gene3D G3DSA:3.30.70.20 68 95 8.9E-9 T 29-03-2018 MC49_RS01965 c64c6c66ac0784cf1dd6c27c5af428bc 182 Gene3D G3DSA:3.30.70.20 19 67 8.8E-12 T 29-03-2018 MC49_RS01965 c64c6c66ac0784cf1dd6c27c5af428bc 182 Gene3D G3DSA:3.30.70.20 96 143 2.9E-15 T 29-03-2018 MC49_RS01965 c64c6c66ac0784cf1dd6c27c5af428bc 182 Gene3D G3DSA:3.30.70.20 144 169 0.035 T 29-03-2018 MC49_RS01965 c64c6c66ac0784cf1dd6c27c5af428bc 182 SUPERFAMILY SSF54862 1 171 5.16E-46 T 29-03-2018 MC49_RS07240 7ea6032eb71af66816f497627b994ee1 478 Pfam PF00245 Alkaline phosphatase 71 437 1.2E-115 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MC49_RS07240 7ea6032eb71af66816f497627b994ee1 478 ProSitePatterns PS00123 Alkaline phosphatase active site. 128 136 - T 29-03-2018 IPR018299 Alkaline phosphatase, active site GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MC49_RS07240 7ea6032eb71af66816f497627b994ee1 478 SMART SM00098 72 478 1.0E-174 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MC49_RS07240 7ea6032eb71af66816f497627b994ee1 478 SUPERFAMILY SSF53649 50 477 1.14E-132 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MC49_RS07240 7ea6032eb71af66816f497627b994ee1 478 Gene3D G3DSA:3.40.720.10 30 478 3.1E-123 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 MC49_RS07240 7ea6032eb71af66816f497627b994ee1 478 PRINTS PR00113 Alkaline phosphatase signature 327 356 1.6E-47 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MC49_RS07240 7ea6032eb71af66816f497627b994ee1 478 PRINTS PR00113 Alkaline phosphatase signature 228 238 1.6E-47 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MC49_RS07240 7ea6032eb71af66816f497627b994ee1 478 PRINTS PR00113 Alkaline phosphatase signature 128 143 1.6E-47 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MC49_RS07240 7ea6032eb71af66816f497627b994ee1 478 PRINTS PR00113 Alkaline phosphatase signature 165 185 1.6E-47 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MC49_RS07240 7ea6032eb71af66816f497627b994ee1 478 PRINTS PR00113 Alkaline phosphatase signature 71 91 1.6E-47 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MC49_RS18970 1cb9d417f9e2d5da95fdbe28246eaf59 369 Gene3D G3DSA:1.20.120.420 9 142 5.7E-39 T 29-03-2018 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 MC49_RS18970 1cb9d417f9e2d5da95fdbe28246eaf59 369 Pfam PF01008 Initiation factor 2 subunit family 52 348 1.0E-55 T 29-03-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 MC49_RS18970 1cb9d417f9e2d5da95fdbe28246eaf59 369 Gene3D G3DSA:3.40.50.10470 143 366 2.0E-57 T 29-03-2018 MC49_RS18970 1cb9d417f9e2d5da95fdbe28246eaf59 369 SUPERFAMILY SSF100950 1 351 3.35E-108 T 29-03-2018 MC49_RS18970 1cb9d417f9e2d5da95fdbe28246eaf59 369 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 38 348 3.4E-88 T 29-03-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 MC49_RS18970 1cb9d417f9e2d5da95fdbe28246eaf59 369 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 20 349 3.6E-122 T 29-03-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 MC49_RS18970 1cb9d417f9e2d5da95fdbe28246eaf59 369 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 7 362 34.063 T 29-03-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 MC49_RS06155 4e1388964e1d3e409def47fabadb32cb 559 Pfam PF05193 Peptidase M16 inactive domain 199 375 5.6E-11 T 29-03-2018 IPR007863 Peptidase M16, C-terminal MC49_RS06155 4e1388964e1d3e409def47fabadb32cb 559 Gene3D G3DSA:3.30.830.10 17 250 7.6E-24 T 29-03-2018 MC49_RS06155 4e1388964e1d3e409def47fabadb32cb 559 Gene3D G3DSA:3.30.830.10 256 471 5.0E-19 T 29-03-2018 MC49_RS06155 4e1388964e1d3e409def47fabadb32cb 559 SUPERFAMILY SSF63411 28 239 5.5E-21 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MC49_RS06155 4e1388964e1d3e409def47fabadb32cb 559 Pfam PF00675 Insulinase (Peptidase family M16) 52 157 6.6E-7 T 29-03-2018 IPR011765 Peptidase M16, N-terminal MC49_RS07580 165aa297ed9522430d2204cd4af17902 280 Pfam PF00892 EamA-like transporter family 142 276 2.0E-11 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MC49_RS07580 165aa297ed9522430d2204cd4af17902 280 Pfam PF00892 EamA-like transporter family 7 129 1.2E-7 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MC49_RS07580 165aa297ed9522430d2204cd4af17902 280 SUPERFAMILY SSF103481 37 134 6.28E-15 T 29-03-2018 MC49_RS07580 165aa297ed9522430d2204cd4af17902 280 SUPERFAMILY SSF103481 177 279 5.75E-13 T 29-03-2018 MC49_RS06495 9de1c35ebba46d34a6d031d378fe8f93 342 Pfam PF08402 TOBE domain 257 336 5.2E-9 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 MC49_RS06495 9de1c35ebba46d34a6d031d378fe8f93 342 Pfam PF00005 ABC transporter 21 161 1.8E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS06495 9de1c35ebba46d34a6d031d378fe8f93 342 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS06495 9de1c35ebba46d34a6d031d378fe8f93 342 SUPERFAMILY SSF52540 4 241 1.39E-86 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS06495 9de1c35ebba46d34a6d031d378fe8f93 342 SMART SM00382 28 211 1.3E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS06495 9de1c35ebba46d34a6d031d378fe8f93 342 SUPERFAMILY SSF50331 254 337 2.78E-6 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal MC49_RS06495 9de1c35ebba46d34a6d031d378fe8f93 342 Gene3D G3DSA:3.40.50.300 2 246 1.8E-77 T 29-03-2018 MC49_RS13620 de334a8868b1fee3dc11bc62214b5e18 152 ProDom PD091196 MEMBRANE UPF0266 TRANSMEMBRANE INNER YOBD PLU2700 LMO0779 PM0830 YPO1755/Y2554/YP1637 LIN0773 21 144 6.0E-41 T 29-03-2018 IPR009328 Protein of unknown function DUF986 MC49_RS13620 de334a8868b1fee3dc11bc62214b5e18 152 Hamap MF_01071 UPF0266 membrane protein YobD [yobD]. 1 152 29.535 T 29-03-2018 IPR009328 Protein of unknown function DUF986 MC49_RS13620 de334a8868b1fee3dc11bc62214b5e18 152 PIRSF PIRSF020687 1 152 3.3E-62 T 29-03-2018 IPR009328 Protein of unknown function DUF986 MC49_RS13620 de334a8868b1fee3dc11bc62214b5e18 152 Pfam PF06173 Protein of unknown function (DUF986) 5 151 8.3E-62 T 29-03-2018 IPR009328 Protein of unknown function DUF986 MC49_RS09985 7d7d687acdefd31c8fd2c66fcc4c7f83 885 Pfam PF13380 CoA binding domain 14 129 1.5E-22 T 29-03-2018 IPR003781 CoA-binding GO:0048037 MC49_RS09985 7d7d687acdefd31c8fd2c66fcc4c7f83 885 SUPERFAMILY SSF52210 125 283 1.44E-35 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MC49_RS09985 7d7d687acdefd31c8fd2c66fcc4c7f83 885 SUPERFAMILY SSF51735 2 136 1.69E-33 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS09985 7d7d687acdefd31c8fd2c66fcc4c7f83 885 Pfam PF13549 ATP-grasp domain 473 694 1.0E-69 T 29-03-2018 MC49_RS09985 7d7d687acdefd31c8fd2c66fcc4c7f83 885 Gene3D G3DSA:3.40.50.261 283 452 3.5E-31 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MC49_RS09985 7d7d687acdefd31c8fd2c66fcc4c7f83 885 Gene3D G3DSA:3.30.470.20 563 708 1.3E-17 T 29-03-2018 MC49_RS09985 7d7d687acdefd31c8fd2c66fcc4c7f83 885 SUPERFAMILY SSF56059 481 692 2.43E-23 T 29-03-2018 MC49_RS09985 7d7d687acdefd31c8fd2c66fcc4c7f83 885 Gene3D G3DSA:3.40.50.720 1 129 8.6E-32 T 29-03-2018 MC49_RS09985 7d7d687acdefd31c8fd2c66fcc4c7f83 885 SUPERFAMILY SSF52210 287 447 3.79E-34 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MC49_RS09985 7d7d687acdefd31c8fd2c66fcc4c7f83 885 Pfam PF13302 Acetyltransferase (GNAT) domain 729 861 1.6E-7 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MC49_RS09985 7d7d687acdefd31c8fd2c66fcc4c7f83 885 Gene3D G3DSA:3.40.50.261 130 282 6.8E-37 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MC49_RS09985 7d7d687acdefd31c8fd2c66fcc4c7f83 885 SMART SM00881 9 104 1.5E-27 T 29-03-2018 IPR003781 CoA-binding GO:0048037 MC49_RS09985 7d7d687acdefd31c8fd2c66fcc4c7f83 885 SUPERFAMILY SSF55729 728 867 8.83E-23 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS09985 7d7d687acdefd31c8fd2c66fcc4c7f83 885 Gene3D G3DSA:3.30.1490.20 500 562 4.5E-25 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MC49_RS09985 7d7d687acdefd31c8fd2c66fcc4c7f83 885 Gene3D G3DSA:3.40.630.30 716 883 2.0E-23 T 29-03-2018 MC49_RS09985 7d7d687acdefd31c8fd2c66fcc4c7f83 885 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 147 280 1.4E-44 T 29-03-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain MC49_RS02140 f8ed65fe33591758fa86fab1a581feb6 433 PIRSF PIRSF004539 1 433 5.2E-173 T 29-03-2018 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 MC49_RS02140 f8ed65fe33591758fa86fab1a581feb6 433 TIGRFAM TIGR00770 Dcu: transporter, anaerobic C4-dicarboxylate uptake (Dcu) family 5 433 4.0E-193 T 29-03-2018 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 MC49_RS02140 f8ed65fe33591758fa86fab1a581feb6 433 Pfam PF03605 Anaerobic c4-dicarboxylate membrane transporter 5 365 9.5E-142 T 29-03-2018 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 MC49_RS02535 ea3f683b06cfffc5477a32a3ee6826ef 263 Gene3D G3DSA:1.10.530.10 35 255 9.0E-24 T 29-03-2018 MC49_RS02535 ea3f683b06cfffc5477a32a3ee6826ef 263 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 122 250 1.4E-16 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 MC49_RS02535 ea3f683b06cfffc5477a32a3ee6826ef 263 SMART SM00047 113 239 1.6E-5 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 MC49_RS16440 54a316d38861c88b01e44d755e868aa5 323 SUPERFAMILY SSF54826 1 98 1.88E-27 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MC49_RS16440 54a316d38861c88b01e44d755e868aa5 323 Gene3D G3DSA:3.20.20.120 113 295 5.0E-36 T 29-03-2018 IPR029065 Enolase C-terminal domain-like MC49_RS16440 54a316d38861c88b01e44d755e868aa5 323 SUPERFAMILY SSF51604 108 315 4.06E-49 T 29-03-2018 IPR029065 Enolase C-terminal domain-like MC49_RS16440 54a316d38861c88b01e44d755e868aa5 323 TIGRFAM TIGR01927 menC_gamma/gm+: o-succinylbenzoate synthase 7 307 3.6E-111 T 29-03-2018 MC49_RS16440 54a316d38861c88b01e44d755e868aa5 323 SMART SM00922 115 210 1.7E-8 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal MC49_RS16440 54a316d38861c88b01e44d755e868aa5 323 Gene3D G3DSA:3.30.390.10 1 112 4.0E-19 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MC49_RS16440 54a316d38861c88b01e44d755e868aa5 323 Hamap MF_00470 o-succinylbenzoate synthase [menC]. 4 320 24.145 T 29-03-2018 IPR010196 o-Succinylbenzoate synthase, MenC type1 GO:0000287|GO:0009234|GO:0016836 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MC49_RS16440 54a316d38861c88b01e44d755e868aa5 323 Pfam PF13378 Enolase C-terminal domain-like 124 272 2.7E-14 T 29-03-2018 IPR029065 Enolase C-terminal domain-like MC49_RS07515 0854de3286d7b58bcdf5967a653cf793 238 SUPERFAMILY SSF46894 136 234 3.97E-21 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MC49_RS07515 0854de3286d7b58bcdf5967a653cf793 238 Pfam PF00072 Response regulator receiver domain 6 113 3.5E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS07515 0854de3286d7b58bcdf5967a653cf793 238 SMART SM00448 4 114 1.1E-37 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS07515 0854de3286d7b58bcdf5967a653cf793 238 Gene3D G3DSA:1.10.10.10 129 238 1.5E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS07515 0854de3286d7b58bcdf5967a653cf793 238 SMART SM00862 156 232 6.1E-15 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MC49_RS07515 0854de3286d7b58bcdf5967a653cf793 238 Gene3D G3DSA:3.40.50.2300 1 128 3.4E-31 T 29-03-2018 MC49_RS07515 0854de3286d7b58bcdf5967a653cf793 238 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 232 3.8E-18 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MC49_RS07515 0854de3286d7b58bcdf5967a653cf793 238 SUPERFAMILY SSF52172 2 124 6.97E-36 T 29-03-2018 IPR011006 CheY-like superfamily MC49_RS13305 c479e5181ef8d99536e79d197236ed33 478 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 55 478 1.9E-127 T 29-03-2018 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 MC49_RS13305 c479e5181ef8d99536e79d197236ed33 478 Pfam PF13437 HlyD family secretion protein 329 445 6.1E-16 T 29-03-2018 MC49_RS13305 c479e5181ef8d99536e79d197236ed33 478 ProSitePatterns PS00543 HlyD family secretion proteins signature. 442 464 - T 29-03-2018 IPR006144 Secretion protein HlyD, conserved site GO:0008565|GO:0009306|GO:0016020 MC49_RS13305 c479e5181ef8d99536e79d197236ed33 478 SUPERFAMILY SSF111369 95 158 6.28E-7 T 29-03-2018 MC49_RS13305 c479e5181ef8d99536e79d197236ed33 478 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 399 422 1.4E-64 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MC49_RS13305 c479e5181ef8d99536e79d197236ed33 478 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 107 127 1.4E-64 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MC49_RS13305 c479e5181ef8d99536e79d197236ed33 478 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 375 399 1.4E-64 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MC49_RS13305 c479e5181ef8d99536e79d197236ed33 478 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 65 88 1.4E-64 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MC49_RS13305 c479e5181ef8d99536e79d197236ed33 478 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 442 457 1.4E-64 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MC49_RS13305 c479e5181ef8d99536e79d197236ed33 478 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 457 477 1.4E-64 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MC49_RS13305 c479e5181ef8d99536e79d197236ed33 478 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 342 363 1.4E-64 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MC49_RS13305 c479e5181ef8d99536e79d197236ed33 478 Gene3D G3DSA:2.40.50.100 75 366 8.4E-16 T 29-03-2018 MC49_RS10705 3a735198081ddc54d20e4dafea003a58 191 Gene3D G3DSA:3.40.50.450 1 190 1.5E-55 T 29-03-2018 MC49_RS10705 3a735198081ddc54d20e4dafea003a58 191 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 5 182 2.4E-55 T 29-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG MC49_RS10705 3a735198081ddc54d20e4dafea003a58 191 SUPERFAMILY SSF102405 3 182 3.97E-58 T 29-03-2018 MC49_RS10705 3a735198081ddc54d20e4dafea003a58 191 Pfam PF03641 Possible lysine decarboxylase 49 177 7.3E-41 T 29-03-2018 IPR031100 LOG family MC49_RS00650 69551a28d257a79818320a06bd26953b 398 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 62 292 4.6E-13 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MC49_RS00650 69551a28d257a79818320a06bd26953b 398 Gene3D G3DSA:1.20.1600.10 41 343 2.1E-35 T 29-03-2018 MC49_RS00650 69551a28d257a79818320a06bd26953b 398 Pfam PF00529 HlyD membrane-fusion protein of T1SS 169 359 7.7E-9 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MC49_RS00650 69551a28d257a79818320a06bd26953b 398 SUPERFAMILY SSF111369 51 299 3.14E-87 T 29-03-2018 MC49_RS00650 69551a28d257a79818320a06bd26953b 398 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 39 374 2.0E-83 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MC49_RS17785 e8db4627b131bc8556393c890802e1a8 150 Gene3D G3DSA:1.10.3600.10 4 122 2.9E-32 T 29-03-2018 IPR009364 Putative bacterial toxin ydaT MC49_RS17785 e8db4627b131bc8556393c890802e1a8 150 Pfam PF06254 Putative bacterial toxin ydaT 58 139 2.9E-24 T 29-03-2018 IPR009364 Putative bacterial toxin ydaT MC49_RS05760 7a10499321529ad22ea0fab0a6ad5c16 639 Gene3D G3DSA:3.40.50.720 278 619 1.8E-60 T 29-03-2018 MC49_RS05760 7a10499321529ad22ea0fab0a6ad5c16 639 SUPERFAMILY SSF53335 131 329 5.98E-16 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS05760 7a10499321529ad22ea0fab0a6ad5c16 639 SUPERFAMILY SSF51735 282 561 2.07E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS05760 7a10499321529ad22ea0fab0a6ad5c16 639 Pfam PF02719 Polysaccharide biosynthesis protein 285 582 4.5E-129 T 29-03-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain MC49_RS05760 7a10499321529ad22ea0fab0a6ad5c16 639 Gene3D G3DSA:3.40.50.720 142 266 3.9E-25 T 29-03-2018 MC49_RS05760 7a10499321529ad22ea0fab0a6ad5c16 639 Pfam PF13727 CoA-binding domain 70 240 1.6E-8 T 29-03-2018 MC49_RS02620 1decee44aff484be78ac8e7966e53bb0 343 SUPERFAMILY SSF53807 39 310 1.96E-42 T 29-03-2018 MC49_RS02620 1decee44aff484be78ac8e7966e53bb0 343 Gene3D G3DSA:3.40.50.1980 165 342 2.4E-27 T 29-03-2018 MC49_RS02620 1decee44aff484be78ac8e7966e53bb0 343 Gene3D G3DSA:3.40.50.1980 38 163 1.9E-14 T 29-03-2018 MC49_RS02620 1decee44aff484be78ac8e7966e53bb0 343 Pfam PF01497 Periplasmic binding protein 79 281 5.5E-17 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 MC49_RS18575 9ba2d8188957d8ef2bcb067d8c9b5d7d 507 Gene3D G3DSA:3.40.50.300 251 501 1.2E-38 T 29-03-2018 MC49_RS18575 9ba2d8188957d8ef2bcb067d8c9b5d7d 507 SUPERFAMILY SSF52540 141 472 8.07E-75 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS18575 9ba2d8188957d8ef2bcb067d8c9b5d7d 507 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 344 358 - T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 MC49_RS18575 9ba2d8188957d8ef2bcb067d8c9b5d7d 507 Gene3D G3DSA:3.30.450.90 125 250 1.1E-40 T 29-03-2018 MC49_RS18575 9ba2d8188957d8ef2bcb067d8c9b5d7d 507 Pfam PF00437 Type II/IV secretion system protein 156 416 1.4E-77 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 MC49_RS03115 8997f72cc4134bd4b57c7d1ff45759f9 102 SUPERFAMILY SSF159871 2 66 9.42E-8 T 29-03-2018 IPR010854 Domain of unknown function DUF1471 MC49_RS03115 8997f72cc4134bd4b57c7d1ff45759f9 102 Pfam PF07338 Protein of unknown function (DUF1471) 23 66 1.6E-5 T 29-03-2018 IPR010854 Domain of unknown function DUF1471 MC49_RS03115 8997f72cc4134bd4b57c7d1ff45759f9 102 Gene3D G3DSA:3.30.1660.10 17 66 9.0E-8 T 29-03-2018 IPR025543 Dodecin-like MC49_RS06305 b309b2375a774dbf2d83c26df95129de 481 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 21 38 - T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 MC49_RS06305 b309b2375a774dbf2d83c26df95129de 481 Gene3D G3DSA:3.30.1360.60 6 83 4.0E-22 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 MC49_RS06305 b309b2375a774dbf2d83c26df95129de 481 SUPERFAMILY SSF55604 9 80 1.83E-17 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 MC49_RS06305 b309b2375a774dbf2d83c26df95129de 481 Pfam PF00367 phosphotransferase system, EIIB 11 43 1.6E-11 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 MC49_RS06305 b309b2375a774dbf2d83c26df95129de 481 Pfam PF02378 Phosphotransferase system, EIIC 126 408 3.1E-32 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 MC49_RS11555 150b859b714e6d8730dc96e3b4c94d23 297 SUPERFAMILY SSF46785 5 86 1.48E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS11555 150b859b714e6d8730dc96e3b4c94d23 297 SUPERFAMILY SSF53850 90 295 3.98E-30 T 29-03-2018 MC49_RS11555 150b859b714e6d8730dc96e3b4c94d23 297 Gene3D G3DSA:3.40.190.10 90 208 2.2E-15 T 29-03-2018 MC49_RS11555 150b859b714e6d8730dc96e3b4c94d23 297 Gene3D G3DSA:3.40.190.10 217 297 0.0016 T 29-03-2018 MC49_RS11555 150b859b714e6d8730dc96e3b4c94d23 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 63 2.7E-14 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS11555 150b859b714e6d8730dc96e3b4c94d23 297 Gene3D G3DSA:1.10.10.10 2 88 4.4E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS11555 150b859b714e6d8730dc96e3b4c94d23 297 Pfam PF03466 LysR substrate binding domain 97 296 1.2E-17 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS10300 87192710d3d0d242bcfeac78de699351 97 Pfam PF01402 Ribbon-helix-helix protein, copG family 52 89 4.6E-7 T 29-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 MC49_RS10300 87192710d3d0d242bcfeac78de699351 97 Gene3D G3DSA:1.10.1220.10 38 90 4.8E-7 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 MC49_RS14325 516401c33b98904e69b60a0cabe66ec7 220 Pfam PF01814 Hemerythrin HHE cation binding domain 79 216 3.3E-25 T 29-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 MC49_RS14325 516401c33b98904e69b60a0cabe66ec7 220 Pfam PF04405 Domain of Unknown function (DUF542) 5 58 4.8E-19 T 29-03-2018 IPR019903 Repair of iron centres family MC49_RS14325 516401c33b98904e69b60a0cabe66ec7 220 Gene3D G3DSA:1.20.120.520 61 218 9.7E-30 T 29-03-2018 MC49_RS14325 516401c33b98904e69b60a0cabe66ec7 220 Gene3D G3DSA:1.10.3910.10 4 60 1.3E-9 T 29-03-2018 MC49_RS14325 516401c33b98904e69b60a0cabe66ec7 220 TIGRFAM TIGR03652 FeS_repair_RIC: iron-sulfur cluster repair di-iron protein 8 216 8.9E-75 T 29-03-2018 IPR019903 Repair of iron centres family MC49_RS16550 4dad4ef6902b9ec6feeddb4eb35cd2ab 193 SUPERFAMILY SSF109604 3 182 4.28E-46 T 29-03-2018 MC49_RS16550 4dad4ef6902b9ec6feeddb4eb35cd2ab 193 Pfam PF13023 HD domain 9 160 2.7E-16 T 29-03-2018 IPR006674 HD domain MC49_RS16550 4dad4ef6902b9ec6feeddb4eb35cd2ab 193 Hamap MF_01100 5'-deoxynucleotidase YfbR [yfbR]. 1 193 44.375 T 29-03-2018 IPR022971 5'-deoxynucleotidase YfbR KEGG: 00240+3.1.3.89 MC49_RS16550 4dad4ef6902b9ec6feeddb4eb35cd2ab 193 SMART SM00471 24 149 7.7E-8 T 29-03-2018 IPR003607 HD/PDEase domain MC49_RS16550 4dad4ef6902b9ec6feeddb4eb35cd2ab 193 ProDom PD353566 UPF0207 HYDROLASE HD PHOSPHOHYDROLASE METAL-DEPENDENT SUBDOMAIN YFBR PHOSPHOHYDROLASE NUCLEOTIDE-BINDING NUCLEOSIDE 78 183 2.0E-37 T 29-03-2018 MC49_RS16550 4dad4ef6902b9ec6feeddb4eb35cd2ab 193 Gene3D G3DSA:1.10.3210.10 1 187 5.7E-51 T 29-03-2018 MC49_RS18010 3a357d7337029a13ed5b8efa22b28d25 250 Hamap MF_00468 Sulfate transporter CysZ [cysZ]. 7 247 28.209 T 29-03-2018 IPR022985 Sulfate transporter CysZ GO:0000103|GO:0005887|GO:0015116 MC49_RS18010 3a357d7337029a13ed5b8efa22b28d25 250 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 13 229 1.2E-41 T 29-03-2018 MC49_RS04405 6faad2ea430ab7469223961d2e50727e 227 SUPERFAMILY SSF53271 49 225 6.69E-34 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like MC49_RS04405 6faad2ea430ab7469223961d2e50727e 227 Gene3D G3DSA:3.40.50.2020 61 227 1.0E-27 T 29-03-2018 MC49_RS04405 6faad2ea430ab7469223961d2e50727e 227 Pfam PF00156 Phosphoribosyl transferase domain 147 224 2.0E-6 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MC49_RS16640 3cd4ac5cb58a53a12a3ecf8559668a68 336 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 6 120 3.7E-24 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MC49_RS16640 3cd4ac5cb58a53a12a3ecf8559668a68 336 SMART SM00859 6 121 1.1E-28 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MC49_RS16640 3cd4ac5cb58a53a12a3ecf8559668a68 336 Gene3D G3DSA:3.40.50.720 1 143 6.0E-26 T 29-03-2018 MC49_RS16640 3cd4ac5cb58a53a12a3ecf8559668a68 336 SUPERFAMILY SSF51735 5 157 7.77E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS16640 3cd4ac5cb58a53a12a3ecf8559668a68 336 Gene3D G3DSA:3.30.360.10 144 313 4.8E-41 T 29-03-2018 MC49_RS16640 3cd4ac5cb58a53a12a3ecf8559668a68 336 SUPERFAMILY SSF55347 132 318 1.41E-47 T 29-03-2018 MC49_RS16640 3cd4ac5cb58a53a12a3ecf8559668a68 336 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 142 315 2.8E-30 T 29-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MC49_RS16640 3cd4ac5cb58a53a12a3ecf8559668a68 336 PIRSF PIRSF000148 4 336 2.7E-90 T 29-03-2018 MC49_RS02000 42e38838a43062856a2de6ad5778f6bd 700 Pfam PF02554 Carbon starvation protein CstA 31 402 1.1E-167 T 29-03-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 MC49_RS02000 42e38838a43062856a2de6ad5778f6bd 700 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 468 595 5.9E-36 T 29-03-2018 IPR025299 CstA, C-terminal domain MC49_RS03015 2164ff6ac0219480572bd23168687169 832 SUPERFAMILY SSF141729 29 151 8.5E-24 T 29-03-2018 MC49_RS03015 2164ff6ac0219480572bd23168687169 832 Pfam PF00577 Outer membrane usher protein 199 747 1.2E-150 T 29-03-2018 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 MC49_RS03015 2164ff6ac0219480572bd23168687169 832 Pfam PF13954 PapC N-terminal domain 30 176 2.0E-35 T 29-03-2018 IPR025885 PapC, N-terminal domain GO:0005515 MC49_RS03015 2164ff6ac0219480572bd23168687169 832 Pfam PF13953 PapC C-terminal domain 761 814 6.0E-14 T 29-03-2018 IPR025949 PapC-like, C-terminal domain MC49_RS06120 6965511980415be2e4f00bbb8b5aca94 583 Gene3D G3DSA:3.10.20.310 104 177 2.0E-7 T 29-03-2018 MC49_RS06120 6965511980415be2e4f00bbb8b5aca94 583 Gene3D G3DSA:2.40.160.50 205 579 4.0E-22 T 29-03-2018 MC49_RS06120 6965511980415be2e4f00bbb8b5aca94 583 Pfam PF08479 POTRA domain, ShlB-type 104 177 5.0E-9 T 29-03-2018 IPR013686 Polypeptide-transport-associated, ShlB-type MC49_RS06120 6965511980415be2e4f00bbb8b5aca94 583 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 238 547 1.1E-53 T 29-03-2018 IPR005565 Haemolysin activator HlyB, C-terminal MC49_RS18445 3b68bf005efc4ba2c31f81e3c7195f9d 364 Hamap MF_00259 Aminomethyltransferase [gcvT]. 1 359 42.792 T 29-03-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 MC49_RS18445 3b68bf005efc4ba2c31f81e3c7195f9d 364 SUPERFAMILY SSF103025 3 277 6.06E-89 T 29-03-2018 MC49_RS18445 3b68bf005efc4ba2c31f81e3c7195f9d 364 SUPERFAMILY SSF101790 272 361 1.19E-24 T 29-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain MC49_RS18445 3b68bf005efc4ba2c31f81e3c7195f9d 364 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 2 359 6.4E-145 T 29-03-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 MC49_RS18445 3b68bf005efc4ba2c31f81e3c7195f9d 364 Gene3D G3DSA:2.40.30.110 277 363 1.4E-16 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 MC49_RS18445 3b68bf005efc4ba2c31f81e3c7195f9d 364 Gene3D G3DSA:4.10.1250.10 232 275 6.5E-14 T 29-03-2018 MC49_RS18445 3b68bf005efc4ba2c31f81e3c7195f9d 364 Gene3D G3DSA:3.30.1360.120 2 131 8.8E-31 T 29-03-2018 MC49_RS18445 3b68bf005efc4ba2c31f81e3c7195f9d 364 PIRSF PIRSF006487 1 362 2.3E-80 T 29-03-2018 MC49_RS18445 3b68bf005efc4ba2c31f81e3c7195f9d 364 Gene3D G3DSA:3.30.1360.120 132 231 7.4E-24 T 29-03-2018 MC49_RS18445 3b68bf005efc4ba2c31f81e3c7195f9d 364 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 263 353 1.6E-16 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 MC49_RS18445 3b68bf005efc4ba2c31f81e3c7195f9d 364 Pfam PF01571 Aminomethyltransferase folate-binding domain 10 254 5.1E-82 T 29-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal MC49_RS16035 4bfaa6d18a1450845bdf757e9573e970 185 PIRSF PIRSF030780 1 182 1.5E-65 T 29-03-2018 IPR016956 Inner membrane protein YdjM MC49_RS16035 4bfaa6d18a1450845bdf757e9573e970 185 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 161 1.6E-33 T 29-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase MC49_RS17790 6ff6a73deb049bf31db594c515d9e014 81 Pfam PF15943 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 6 65 3.6E-10 T 29-03-2018 IPR031856 Putative bacterial antitoxin YdaS MC49_RS17790 6ff6a73deb049bf31db594c515d9e014 81 Gene3D G3DSA:1.10.260.40 4 67 1.2E-10 T 29-03-2018 MC49_RS17790 6ff6a73deb049bf31db594c515d9e014 81 SUPERFAMILY SSF47413 12 62 1.01E-5 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS02300 0d227089d4b8f82ab77fea30f99e8cfd 872 Gene3D G3DSA:2.160.20.20 32 528 4.7E-54 T 29-03-2018 IPR012332 P22 tailspike C-terminal domain-like MC49_RS02300 0d227089d4b8f82ab77fea30f99e8cfd 872 Gene3D G3DSA:2.40.128.130 546 872 2.7E-52 T 29-03-2018 MC49_RS02300 0d227089d4b8f82ab77fea30f99e8cfd 872 Pfam PF03797 Autotransporter beta-domain 591 850 6.7E-47 T 29-03-2018 IPR005546 Autotransporter beta-domain MC49_RS02300 0d227089d4b8f82ab77fea30f99e8cfd 872 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 421 872 1.3E-120 T 29-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 MC49_RS02300 0d227089d4b8f82ab77fea30f99e8cfd 872 SUPERFAMILY SSF103515 556 872 7.32E-49 T 29-03-2018 IPR005546 Autotransporter beta-domain MC49_RS02300 0d227089d4b8f82ab77fea30f99e8cfd 872 SMART SM00869 588 861 1.8E-39 T 29-03-2018 IPR005546 Autotransporter beta-domain MC49_RS02300 0d227089d4b8f82ab77fea30f99e8cfd 872 SUPERFAMILY SSF51126 68 524 2.61E-36 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor MC49_RS11520 e916aca85ec4501323f622d030ae0141 724 SUPERFAMILY SSF53383 107 565 5.7E-119 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS11520 e916aca85ec4501323f622d030ae0141 724 SUPERFAMILY SSF55904 570 717 4.84E-44 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 MC49_RS11520 e916aca85ec4501323f622d030ae0141 724 Gene3D G3DSA:3.40.640.10 107 418 3.0E-37 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS11520 e916aca85ec4501323f622d030ae0141 724 SUPERFAMILY SSF52172 1 106 3.03E-9 T 29-03-2018 IPR011006 CheY-like superfamily MC49_RS11520 e916aca85ec4501323f622d030ae0141 724 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 107 548 1.2E-187 T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 MC49_RS11520 e916aca85ec4501323f622d030ae0141 724 PIRSF PIRSF009393 16 718 2.6E-272 T 29-03-2018 IPR011193 Ornithine/lysine/arginine decarboxylase GO:0005737|GO:0006520|GO:0016831 MC49_RS11520 e916aca85ec4501323f622d030ae0141 724 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 348 362 - T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 MC49_RS11520 e916aca85ec4501323f622d030ae0141 724 Gene3D G3DSA:3.90.100.10 599 724 1.2E-33 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 MC49_RS11520 e916aca85ec4501323f622d030ae0141 724 Gene3D G3DSA:3.90.1150.10 419 598 4.0E-51 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS11520 e916aca85ec4501323f622d030ae0141 724 Gene3D G3DSA:3.40.50.220 4 106 2.4E-16 T 29-03-2018 IPR027464 Ornithine decarboxylase, N-terminal domain KEGG: 00330+4.1.1.17|KEGG: 00480+4.1.1.17|MetaCyc: PWY-46|MetaCyc: PWY-6305 MC49_RS11520 e916aca85ec4501323f622d030ae0141 724 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 574 703 4.9E-48 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 MC49_RS09765 1dbae79e6f35b935c7b09cc39383e8c9 152 Hamap MF_01903 Xanthine phosphoribosyltransferase [gpt]. 1 152 40.94 T 29-03-2018 IPR023747 Xanthine-guanine phosphoribosyltransferase GO:0000310 KEGG: 00230+2.4.2.22 MC49_RS09765 1dbae79e6f35b935c7b09cc39383e8c9 152 Gene3D G3DSA:3.40.50.2020 1 152 1.6E-27 T 29-03-2018 MC49_RS09765 1dbae79e6f35b935c7b09cc39383e8c9 152 SUPERFAMILY SSF53271 4 144 7.18E-32 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like MC49_RS09765 1dbae79e6f35b935c7b09cc39383e8c9 152 Pfam PF00156 Phosphoribosyl transferase domain 12 145 6.7E-16 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MC49_RS09010 a437482ab1ce0485f0f9c180db8ab0c5 435 Gene3D G3DSA:2.40.50.100 46 91 2.5E-6 T 29-03-2018 MC49_RS09010 a437482ab1ce0485f0f9c180db8ab0c5 435 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 22 435 6.8E-93 T 29-03-2018 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 MC49_RS09010 a437482ab1ce0485f0f9c180db8ab0c5 435 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 303 324 1.9E-50 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MC49_RS09010 a437482ab1ce0485f0f9c180db8ab0c5 435 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 70 90 1.9E-50 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MC49_RS09010 a437482ab1ce0485f0f9c180db8ab0c5 435 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 28 51 1.9E-50 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MC49_RS09010 a437482ab1ce0485f0f9c180db8ab0c5 435 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 399 414 1.9E-50 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MC49_RS09010 a437482ab1ce0485f0f9c180db8ab0c5 435 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 336 360 1.9E-50 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MC49_RS09010 a437482ab1ce0485f0f9c180db8ab0c5 435 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 414 434 1.9E-50 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MC49_RS09010 a437482ab1ce0485f0f9c180db8ab0c5 435 Pfam PF13437 HlyD family secretion protein 290 402 1.1E-16 T 29-03-2018 MC49_RS09010 a437482ab1ce0485f0f9c180db8ab0c5 435 Gene3D G3DSA:1.20.1600.10 141 391 5.6E-10 T 29-03-2018 MC49_RS09010 a437482ab1ce0485f0f9c180db8ab0c5 435 Pfam PF13533 Biotin-lipoyl like 61 104 1.0E-6 T 29-03-2018 MC49_RS11265 f2f63f01db0e07b97cd93340784cd57e 704 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 195 206 - T 29-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MC49_RS11265 f2f63f01db0e07b97cd93340784cd57e 704 Gene3D G3DSA:3.40.50.150 495 701 3.6E-42 T 29-03-2018 MC49_RS11265 f2f63f01db0e07b97cd93340784cd57e 704 SUPERFAMILY SSF53335 394 700 4.96E-68 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS11265 f2f63f01db0e07b97cd93340784cd57e 704 Pfam PF02926 THUMP domain 18 153 2.0E-15 T 29-03-2018 IPR004114 THUMP domain GO:0003723 MC49_RS11265 f2f63f01db0e07b97cd93340784cd57e 704 PIRSF PIRSF037618 1 702 6.9E-300 T 29-03-2018 IPR017244 Ribosomal RNA large subunit methyltransferase K/L GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MC49_RS11265 f2f63f01db0e07b97cd93340784cd57e 704 Gene3D G3DSA:3.30.750.80 391 494 7.2E-8 T 29-03-2018 MC49_RS11265 f2f63f01db0e07b97cd93340784cd57e 704 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 306 312 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MC49_RS11265 f2f63f01db0e07b97cd93340784cd57e 704 SMART SM00981 56 154 2.3E-22 T 29-03-2018 IPR004114 THUMP domain GO:0003723 MC49_RS11265 f2f63f01db0e07b97cd93340784cd57e 704 Pfam PF01170 Putative RNA methylase family UPF0020 162 375 5.4E-61 T 29-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MC49_RS11265 f2f63f01db0e07b97cd93340784cd57e 704 Gene3D G3DSA:3.40.50.150 169 390 2.9E-32 T 29-03-2018 MC49_RS11265 f2f63f01db0e07b97cd93340784cd57e 704 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 474 656 1.4E-19 T 29-03-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 MC49_RS11265 f2f63f01db0e07b97cd93340784cd57e 704 SUPERFAMILY SSF53335 258 373 1.57E-36 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS11265 f2f63f01db0e07b97cd93340784cd57e 704 SUPERFAMILY SSF53335 144 217 1.57E-36 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS11265 f2f63f01db0e07b97cd93340784cd57e 704 Hamap MF_01858 Ribosomal RNA large subunit methyltransferase K/L [rlmL]. 4 701 32.612 T 29-03-2018 IPR017244 Ribosomal RNA large subunit methyltransferase K/L GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MC49_RS16565 6d5a5fbbe6e2609b0665abf63d9d1b6b 164 SUPERFAMILY SSF116960 1 164 2.09E-67 T 29-03-2018 MC49_RS16565 6d5a5fbbe6e2609b0665abf63d9d1b6b 164 PIRSF PIRSF006272 1 164 3.2E-75 T 29-03-2018 IPR005587 Uncharacterised protein family UPF0304, YfbU MC49_RS16565 6d5a5fbbe6e2609b0665abf63d9d1b6b 164 Gene3D G3DSA:1.10.287.680 1 47 2.3E-26 T 29-03-2018 IPR023145 YfbU, helix-hairpin domain MC49_RS16565 6d5a5fbbe6e2609b0665abf63d9d1b6b 164 Hamap MF_00762 UPF0304 protein YfbU [yfbU]. 1 164 38.066 T 29-03-2018 IPR005587 Uncharacterised protein family UPF0304, YfbU MC49_RS16565 6d5a5fbbe6e2609b0665abf63d9d1b6b 164 Gene3D G3DSA:1.10.3190.10 54 164 5.4E-42 T 29-03-2018 IPR023146 YfbU, alpha-helical bundle domain MC49_RS16565 6d5a5fbbe6e2609b0665abf63d9d1b6b 164 Pfam PF03887 YfbU domain 1 164 5.0E-71 T 29-03-2018 IPR005587 Uncharacterised protein family UPF0304, YfbU MC49_RS16565 6d5a5fbbe6e2609b0665abf63d9d1b6b 164 ProDom PD035118 UPF0304 YFBU PLASMID YPO2563/Y1624/YP2374 YBFU PM1500 OXYGEN ECA3037 VV12093 PROTEIN 1 164 7.0E-79 T 29-03-2018 IPR005587 Uncharacterised protein family UPF0304, YfbU MC49_RS05830 1d358789eec2d4492e464c72361c11b8 450 ProSitePatterns PS00942 glpT family of transporters signature. 153 169 - T 29-03-2018 IPR021159 Glycerate/sugar phosphate transporter, conserved site GO:0005215|GO:0006810|GO:0016021 Reactome: R-HSA-70153 MC49_RS05830 1d358789eec2d4492e464c72361c11b8 450 TIGRFAM TIGR00881 2A0104: phosphoglycerate transporter family protein 35 417 9.2E-161 T 29-03-2018 MC49_RS05830 1d358789eec2d4492e464c72361c11b8 450 PIRSF PIRSF002808 5 450 3.4E-168 T 29-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 MC49_RS05830 1d358789eec2d4492e464c72361c11b8 450 Gene3D G3DSA:1.20.1250.20 18 224 1.8E-35 T 29-03-2018 MC49_RS05830 1d358789eec2d4492e464c72361c11b8 450 Gene3D G3DSA:1.20.1250.20 240 450 1.7E-30 T 29-03-2018 MC49_RS05830 1d358789eec2d4492e464c72361c11b8 450 Pfam PF07690 Major Facilitator Superfamily 34 400 7.1E-48 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS05830 1d358789eec2d4492e464c72361c11b8 450 SUPERFAMILY SSF103473 16 442 6.67E-84 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS05830 1d358789eec2d4492e464c72361c11b8 450 TIGRFAM TIGR00712 glpT: glycerol-3-phosphate transporter 1 440 2.5E-250 T 29-03-2018 IPR005267 Glycerol-3-phosphate transporter GO:0015169|GO:0015794|GO:0016021 MC49_RS14250 afb185f6cf46351d2d3df76c1c533b40 94 Pfam PF05166 YcgL domain 3 75 1.1E-31 T 29-03-2018 IPR027354 YcgL domain MC49_RS14250 afb185f6cf46351d2d3df76c1c533b40 94 SUPERFAMILY SSF160191 1 92 2.35E-37 T 29-03-2018 MC49_RS14250 afb185f6cf46351d2d3df76c1c533b40 94 Hamap MF_01866 Protein YcgL [ycgL]. 1 88 26.511 T 29-03-2018 IPR027354 YcgL domain MC49_RS14250 afb185f6cf46351d2d3df76c1c533b40 94 ProDom PD030374 YCGL UNCHARACTERIZED SIMILAR BACTERIA HI1446 Y2231 HYDROLASE CYTOPLASMIC YPO2080 SO2575 1 81 1.0E-28 T 29-03-2018 IPR027354 YcgL domain MC49_RS00475 fd3f68ff5c3fd0cba7966606b6698f9d 421 Pfam PF07690 Major Facilitator Superfamily 23 248 3.4E-12 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS00475 fd3f68ff5c3fd0cba7966606b6698f9d 421 Gene3D G3DSA:1.20.1250.20 217 411 4.1E-24 T 29-03-2018 MC49_RS00475 fd3f68ff5c3fd0cba7966606b6698f9d 421 Gene3D G3DSA:1.20.1250.20 6 204 1.3E-22 T 29-03-2018 MC49_RS00475 fd3f68ff5c3fd0cba7966606b6698f9d 421 SUPERFAMILY SSF103473 5 410 4.71E-49 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS15795 b72e81db36e2cb93ed1c6e9faaee8284 139 Gene3D G3DSA:3.90.1010.10 2 138 7.8E-49 T 29-03-2018 MC49_RS15795 b72e81db36e2cb93ed1c6e9faaee8284 139 Pfam PF02657 Fe-S metabolism associated domain 13 132 2.8E-45 T 29-03-2018 IPR003808 Fe-S metabolism associated domain, SufE-like MC49_RS15795 b72e81db36e2cb93ed1c6e9faaee8284 139 SUPERFAMILY SSF82649 5 136 4.53E-47 T 29-03-2018 MC49_RS16135 f903b0c991f7be39bfb9c7086292f71f 342 SUPERFAMILY SSF53448 10 243 2.53E-51 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MC49_RS16135 f903b0c991f7be39bfb9c7086292f71f 342 Gene3D G3DSA:3.90.550.10 7 277 1.5E-46 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MC49_RS16135 f903b0c991f7be39bfb9c7086292f71f 342 Pfam PF00535 Glycosyl transferase family 2 13 132 3.5E-28 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MC49_RS02520 62f4670e0a34e472c06526b611a68d6c 232 PRINTS PR00969 Pili chaperone signature 159 174 2.2E-33 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS02520 62f4670e0a34e472c06526b611a68d6c 232 PRINTS PR00969 Pili chaperone signature 98 115 2.2E-33 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS02520 62f4670e0a34e472c06526b611a68d6c 232 PRINTS PR00969 Pili chaperone signature 124 139 2.2E-33 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS02520 62f4670e0a34e472c06526b611a68d6c 232 PRINTS PR00969 Pili chaperone signature 21 30 2.2E-33 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS02520 62f4670e0a34e472c06526b611a68d6c 232 PRINTS PR00969 Pili chaperone signature 70 91 2.2E-33 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS02520 62f4670e0a34e472c06526b611a68d6c 232 ProSitePatterns PS00635 Gram-negative pili assembly chaperone signature. 97 114 - T 29-03-2018 IPR018046 Pili assembly chaperone, conserved site MC49_RS02520 62f4670e0a34e472c06526b611a68d6c 232 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 21 142 7.8E-44 T 29-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 MC49_RS02520 62f4670e0a34e472c06526b611a68d6c 232 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 165 225 3.8E-13 T 29-03-2018 IPR016148 Pili assembly chaperone, C-terminal MC49_RS02520 62f4670e0a34e472c06526b611a68d6c 232 Gene3D G3DSA:2.60.40.10 20 143 1.9E-37 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS02520 62f4670e0a34e472c06526b611a68d6c 232 SUPERFAMILY SSF49584 136 228 9.94E-17 T 29-03-2018 IPR016148 Pili assembly chaperone, C-terminal MC49_RS02520 62f4670e0a34e472c06526b611a68d6c 232 SUPERFAMILY SSF49354 16 142 2.09E-41 T 29-03-2018 IPR008962 PapD-like MC49_RS02520 62f4670e0a34e472c06526b611a68d6c 232 Gene3D G3DSA:2.60.40.10 145 228 2.8E-17 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS07910 8b5754b8a67c6cef834ea8d79e2f62d6 416 SUPERFAMILY SSF53187 330 406 3.14E-54 T 29-03-2018 MC49_RS07910 8b5754b8a67c6cef834ea8d79e2f62d6 416 SUPERFAMILY SSF53187 187 283 3.14E-54 T 29-03-2018 MC49_RS07910 8b5754b8a67c6cef834ea8d79e2f62d6 416 Pfam PF11741 AMIN domain 39 142 7.8E-25 T 29-03-2018 IPR021731 AMIN domain MC49_RS07910 8b5754b8a67c6cef834ea8d79e2f62d6 416 SMART SM00646 249 403 5.0E-67 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 MC49_RS07910 8b5754b8a67c6cef834ea8d79e2f62d6 416 Gene3D G3DSA:3.40.630.40 184 410 5.7E-57 T 29-03-2018 MC49_RS07910 8b5754b8a67c6cef834ea8d79e2f62d6 416 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 189 403 4.1E-50 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 MC49_RS05910 518bb4e9d95a12e0ccef9a1158c95dca 111 SUPERFAMILY SSF69118 4 107 1.44E-29 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MC49_RS05910 518bb4e9d95a12e0ccef9a1158c95dca 111 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 40 89 1.8E-19 T 29-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MC49_RS05910 518bb4e9d95a12e0ccef9a1158c95dca 111 Gene3D G3DSA:1.20.1290.10 1 111 2.3E-24 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MC49_RS05910 518bb4e9d95a12e0ccef9a1158c95dca 111 Pfam PF02627 Carboxymuconolactone decarboxylase family 23 105 4.2E-22 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MC49_RS00770 deca1e643297eeb9b5af8a4d336020f0 506 Gene3D G3DSA:1.20.1250.20 12 219 1.3E-21 T 29-03-2018 MC49_RS00770 deca1e643297eeb9b5af8a4d336020f0 506 Gene3D G3DSA:1.20.1250.20 220 417 8.4E-19 T 29-03-2018 MC49_RS00770 deca1e643297eeb9b5af8a4d336020f0 506 SUPERFAMILY SSF103473 23 415 1.16E-43 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS00770 deca1e643297eeb9b5af8a4d336020f0 506 Pfam PF07690 Major Facilitator Superfamily 28 377 1.0E-28 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS04055 754436ccdf173b8a065084427dd3c67b 38 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 38 4.9E-22 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS04055 754436ccdf173b8a065084427dd3c67b 38 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 38 18.073 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS04055 754436ccdf173b8a065084427dd3c67b 38 Pfam PF00444 Ribosomal protein L36 1 38 2.2E-20 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS04055 754436ccdf173b8a065084427dd3c67b 38 SUPERFAMILY SSF57840 1 38 5.76E-17 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS04055 754436ccdf173b8a065084427dd3c67b 38 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 37 - T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS04055 754436ccdf173b8a065084427dd3c67b 38 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 38 1.0E-9 T 29-03-2018 MC49_RS11120 845de08190498ccd644e6bc37e6cea8f 425 ProSitePatterns PS00885 EPSP synthase signature 2. 338 356 - T 29-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MC49_RS11120 845de08190498ccd644e6bc37e6cea8f 425 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 420 4.4E-151 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 MC49_RS11120 845de08190498ccd644e6bc37e6cea8f 425 Gene3D G3DSA:3.65.10.10 227 425 2.8E-69 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 MC49_RS11120 845de08190498ccd644e6bc37e6cea8f 425 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 14 423 2.9E-140 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MC49_RS11120 845de08190498ccd644e6bc37e6cea8f 425 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 10 425 33.809 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MC49_RS11120 845de08190498ccd644e6bc37e6cea8f 425 Gene3D G3DSA:3.65.10.10 21 226 3.6E-62 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 MC49_RS11120 845de08190498ccd644e6bc37e6cea8f 425 SUPERFAMILY SSF55205 1 423 2.75E-142 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 MC49_RS11120 845de08190498ccd644e6bc37e6cea8f 425 PIRSF PIRSF000505 2 425 8.4E-152 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MC49_RS11120 845de08190498ccd644e6bc37e6cea8f 425 ProSitePatterns PS00104 EPSP synthase signature 1. 90 104 - T 29-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MC49_RS15035 f4d1c7868b148f8ed3a0407382efda99 364 TIGRFAM TIGR01946 rnfD: electron transport complex, RnfABCDGE type, D subunit 19 359 4.4E-139 T 29-03-2018 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 MC49_RS15035 f4d1c7868b148f8ed3a0407382efda99 364 Pfam PF03116 NQR2, RnfD, RnfE family 17 358 4.4E-106 T 29-03-2018 IPR004338 NADH-quinone reductase NQR2/RnfD GO:0006810|GO:0016020 MC49_RS15035 f4d1c7868b148f8ed3a0407382efda99 364 Hamap MF_00462 Electron transport complex subunit RsxD [rsxD]. 14 360 28.385 T 29-03-2018 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 MC49_RS00855 70a4622d6ea93352f8c6f60a89bdbab1 137 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 6 132 2.4E-46 T 29-03-2018 IPR011605 NusB antitermination factor GO:0006353 MC49_RS00855 70a4622d6ea93352f8c6f60a89bdbab1 137 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 4 135 24.533 T 29-03-2018 IPR011605 NusB antitermination factor GO:0006353 MC49_RS00855 70a4622d6ea93352f8c6f60a89bdbab1 137 Pfam PF01029 NusB family 7 131 9.9E-38 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 MC49_RS00855 70a4622d6ea93352f8c6f60a89bdbab1 137 Gene3D G3DSA:1.10.940.10 1 137 7.7E-45 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 MC49_RS00855 70a4622d6ea93352f8c6f60a89bdbab1 137 SUPERFAMILY SSF48013 3 135 1.83E-44 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 MC49_RS14540 7f075b6d9fd3ada7050ea88ed994278d 198 Gene3D G3DSA:1.10.10.60 45 64 3.7E-11 T 29-03-2018 MC49_RS14540 7f075b6d9fd3ada7050ea88ed994278d 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 53 5.4E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS14540 7f075b6d9fd3ada7050ea88ed994278d 198 Pfam PF16925 Bacterial transcriptional repressor C-terminal 85 189 6.6E-12 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MC49_RS14540 7f075b6d9fd3ada7050ea88ed994278d 198 SUPERFAMILY SSF46689 7 79 1.08E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS14540 7f075b6d9fd3ada7050ea88ed994278d 198 Gene3D G3DSA:1.10.357.10 65 195 2.4E-22 T 29-03-2018 MC49_RS14540 7f075b6d9fd3ada7050ea88ed994278d 198 SUPERFAMILY SSF48498 81 194 1.29E-20 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MC49_RS14540 7f075b6d9fd3ada7050ea88ed994278d 198 Gene3D G3DSA:1.10.10.60 2 44 2.5E-12 T 29-03-2018 MC49_RS00375 9364c07f15c507179e15ce4150dfc353 198 SUPERFAMILY SSF52980 2 191 6.43E-45 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MC49_RS00375 9364c07f15c507179e15ce4150dfc353 198 Pfam PF09588 YqaJ-like viral recombinase domain 7 145 8.2E-21 T 29-03-2018 IPR019080 YqaJ viral recombinase MC49_RS00375 9364c07f15c507179e15ce4150dfc353 198 TIGRFAM TIGR03033 phage_rel_nuc: putative phage-type endonuclease 2 154 2.2E-22 T 29-03-2018 IPR017482 Putative phage-type endonuclease MC49_RS00375 9364c07f15c507179e15ce4150dfc353 198 Gene3D G3DSA:3.90.320.10 1 198 1.9E-51 T 29-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 MC49_RS12275 c9548653c5e6022b4a0f46d453d3a36f 191 Gene3D G3DSA:3.40.50.150 19 184 2.1E-12 T 29-03-2018 MC49_RS12275 c9548653c5e6022b4a0f46d453d3a36f 191 SUPERFAMILY SSF53335 15 168 6.19E-17 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS03550 ff4d5aa2e4eb19a62ba4ec54e8f1ea3b 105 Gene3D G3DSA:2.40.50.140 3 105 4.1E-14 T 29-03-2018 MC49_RS03550 ff4d5aa2e4eb19a62ba4ec54e8f1ea3b 105 Hamap MF_00720 Primosomal replication protein N [priB]. 3 101 25.074 T 29-03-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 MC49_RS03550 ff4d5aa2e4eb19a62ba4ec54e8f1ea3b 105 PIRSF PIRSF003135 1 102 4.2E-49 T 29-03-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 MC49_RS03550 ff4d5aa2e4eb19a62ba4ec54e8f1ea3b 105 Pfam PF00436 Single-strand binding protein family 4 87 6.2E-14 T 29-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 MC49_RS03550 ff4d5aa2e4eb19a62ba4ec54e8f1ea3b 105 SUPERFAMILY SSF50249 3 104 5.83E-32 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS03550 ff4d5aa2e4eb19a62ba4ec54e8f1ea3b 105 TIGRFAM TIGR04418 PriB_gamma: primosomal replication protein PriB 4 100 1.9E-38 T 29-03-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 MC49_RS08045 edd97ff8aa2791953d9ba7ffb94a3838 185 Gene3D G3DSA:1.10.132.20 75 184 2.7E-38 T 29-03-2018 MC49_RS08045 edd97ff8aa2791953d9ba7ffb94a3838 185 Gene3D G3DSA:1.10.132.20 2 74 2.0E-10 T 29-03-2018 MC49_RS08045 edd97ff8aa2791953d9ba7ffb94a3838 185 SUPERFAMILY SSF55194 2 184 2.88E-72 T 29-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 MC49_RS08045 edd97ff8aa2791953d9ba7ffb94a3838 185 Pfam PF01765 Ribosome recycling factor 20 183 5.5E-63 T 29-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 MC49_RS08045 edd97ff8aa2791953d9ba7ffb94a3838 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 27.847 T 29-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 MC49_RS08045 edd97ff8aa2791953d9ba7ffb94a3838 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 2.0E-79 T 29-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 MC49_RS08760 4852959ce0d18420381fe78412cc9b2d 542 TIGRFAM TIGR02231 TIGR02231: conserved hypothetical protein 36 539 8.0E-77 T 29-03-2018 IPR011935 Conserved hypothetical protein CHP02231 MC49_RS08760 4852959ce0d18420381fe78412cc9b2d 542 Pfam PF13598 Domain of unknown function (DUF4139) 221 535 1.0E-53 T 29-03-2018 IPR011935 Conserved hypothetical protein CHP02231 MC49_RS08760 4852959ce0d18420381fe78412cc9b2d 542 Pfam PF13600 N-terminal domain of unknown function (DUF4140) 39 136 2.0E-12 T 29-03-2018 IPR025554 Domain of unknown function DUF4140 MC49_RS07890 a669ca52f4018dc17276107bd1a9bc9f 960 SUPERFAMILY SSF63411 504 728 9.43E-36 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MC49_RS07890 a669ca52f4018dc17276107bd1a9bc9f 960 SUPERFAMILY SSF63411 33 262 1.5E-51 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MC49_RS07890 a669ca52f4018dc17276107bd1a9bc9f 960 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 75 98 - T 29-03-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 MC49_RS07890 a669ca52f4018dc17276107bd1a9bc9f 960 Gene3D G3DSA:3.30.830.10 19 262 5.2E-73 T 29-03-2018 MC49_RS07890 a669ca52f4018dc17276107bd1a9bc9f 960 SUPERFAMILY SSF63411 265 502 1.45E-64 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MC49_RS07890 a669ca52f4018dc17276107bd1a9bc9f 960 Gene3D G3DSA:3.30.830.10 722 960 8.1E-37 T 29-03-2018 MC49_RS07890 a669ca52f4018dc17276107bd1a9bc9f 960 Pfam PF05193 Peptidase M16 inactive domain 681 857 2.5E-10 T 29-03-2018 IPR007863 Peptidase M16, C-terminal MC49_RS07890 a669ca52f4018dc17276107bd1a9bc9f 960 Pfam PF05193 Peptidase M16 inactive domain 215 392 5.0E-24 T 29-03-2018 IPR007863 Peptidase M16, C-terminal MC49_RS07890 a669ca52f4018dc17276107bd1a9bc9f 960 Gene3D G3DSA:3.30.830.10 272 502 4.7E-59 T 29-03-2018 MC49_RS07890 a669ca52f4018dc17276107bd1a9bc9f 960 Pfam PF00675 Insulinase (Peptidase family M16) 55 191 5.7E-32 T 29-03-2018 IPR011765 Peptidase M16, N-terminal MC49_RS07890 a669ca52f4018dc17276107bd1a9bc9f 960 SUPERFAMILY SSF63411 750 954 4.33E-41 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MC49_RS07890 a669ca52f4018dc17276107bd1a9bc9f 960 Gene3D G3DSA:3.30.830.10 503 721 3.5E-25 T 29-03-2018 MC49_RS07890 a669ca52f4018dc17276107bd1a9bc9f 960 Pfam PF16187 Middle or third domain of peptidase_M16 400 677 5.1E-61 T 29-03-2018 IPR032632 Peptidase M16, middle/third domain MC49_RS12365 f2a4a0fd6517862df8cadf82cb0ba99a 350 TIGRFAM TIGR00856 pyrC_dimer: dihydroorotase, homodimeric type 8 347 2.9E-150 T 29-03-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MC49_RS12365 f2a4a0fd6517862df8cadf82cb0ba99a 350 SUPERFAMILY SSF51556 7 346 8.93E-146 T 29-03-2018 IPR032466 Metal-dependent hydrolase MC49_RS12365 f2a4a0fd6517862df8cadf82cb0ba99a 350 Gene3D G3DSA:3.20.20.140 14 348 4.5E-53 T 29-03-2018 MC49_RS12365 f2a4a0fd6517862df8cadf82cb0ba99a 350 ProSitePatterns PS00483 Dihydroorotase signature 2. 249 260 - T 29-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MC49_RS12365 f2a4a0fd6517862df8cadf82cb0ba99a 350 ProSitePatterns PS00482 Dihydroorotase signature 1. 15 23 - T 29-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MC49_RS12365 f2a4a0fd6517862df8cadf82cb0ba99a 350 Hamap MF_00219 Dihydroorotase [pyrC]. 6 347 54.151 T 29-03-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MC49_RS12365 f2a4a0fd6517862df8cadf82cb0ba99a 350 Pfam PF01979 Amidohydrolase family 15 311 1.9E-20 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MC49_RS12365 f2a4a0fd6517862df8cadf82cb0ba99a 350 PIRSF PIRSF001237 4 349 3.5E-138 T 29-03-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MC49_RS00760 99995d0fce0389a6e2c91105e5422ff2 109 PIRSF PIRSF003113 2 106 7.5E-34 T 29-03-2018 IPR002634 BolA protein MC49_RS00760 99995d0fce0389a6e2c91105e5422ff2 109 Pfam PF01722 BolA-like protein 17 90 6.9E-30 T 29-03-2018 IPR002634 BolA protein MC49_RS00760 99995d0fce0389a6e2c91105e5422ff2 109 Gene3D G3DSA:3.30.300.90 4 97 2.4E-29 T 29-03-2018 MC49_RS00760 99995d0fce0389a6e2c91105e5422ff2 109 SUPERFAMILY SSF82657 6 94 9.02E-30 T 29-03-2018 IPR002634 BolA protein MC49_RS05565 f25f24cbf60f9fb61bc9500a2ffdbd02 314 SUPERFAMILY SSF53448 8 242 2.16E-32 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MC49_RS05565 f25f24cbf60f9fb61bc9500a2ffdbd02 314 Pfam PF00535 Glycosyl transferase family 2 11 132 5.4E-17 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MC49_RS05565 f25f24cbf60f9fb61bc9500a2ffdbd02 314 Gene3D G3DSA:3.90.550.10 1 306 3.7E-29 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MC49_RS09490 3e304e27c123e80c8f6e18639646b76f 566 SUPERFAMILY SSF161098 22 282 1.74E-43 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS09490 3e304e27c123e80c8f6e18639646b76f 566 SUPERFAMILY SSF161098 295 555 1.96E-37 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS09490 3e304e27c123e80c8f6e18639646b76f 566 Gene3D G3DSA:1.10.3720.10 24 287 6.5E-32 T 29-03-2018 MC49_RS09490 3e304e27c123e80c8f6e18639646b76f 566 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 274 2.5E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS09490 3e304e27c123e80c8f6e18639646b76f 566 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 385 553 2.3E-10 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS09490 3e304e27c123e80c8f6e18639646b76f 566 Gene3D G3DSA:1.10.3720.10 335 557 2.7E-26 T 29-03-2018 MC49_RS16115 570dfa428f8c16ce74ae3d5d2eb07978 237 Gene3D G3DSA:3.30.200.20 1 93 1.2E-23 T 29-03-2018 MC49_RS16115 570dfa428f8c16ce74ae3d5d2eb07978 237 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 3 235 6.2E-81 T 29-03-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 MC49_RS16115 570dfa428f8c16ce74ae3d5d2eb07978 237 Pfam PF01259 SAICAR synthetase 7 231 1.5E-57 T 29-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MC49_RS16115 570dfa428f8c16ce74ae3d5d2eb07978 237 ProSitePatterns PS01058 SAICAR synthetase signature 2. 173 181 - T 29-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MC49_RS16115 570dfa428f8c16ce74ae3d5d2eb07978 237 SUPERFAMILY SSF56104 3 232 2.71E-74 T 29-03-2018 MC49_RS16115 570dfa428f8c16ce74ae3d5d2eb07978 237 Gene3D G3DSA:3.30.470.20 94 220 3.7E-44 T 29-03-2018 MC49_RS16115 570dfa428f8c16ce74ae3d5d2eb07978 237 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 4 234 28.559 T 29-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MC49_RS16115 570dfa428f8c16ce74ae3d5d2eb07978 237 ProSitePatterns PS01057 SAICAR synthetase signature 1. 86 100 - T 29-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MC49_RS01660 ce1811a739d4867e52c7850ed6e558cd 489 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 426 2.0E-172 T 29-03-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 MC49_RS01660 ce1811a739d4867e52c7850ed6e558cd 489 Pfam PF10150 Ribonuclease E/G family 124 393 2.2E-102 T 29-03-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 MC49_RS01660 ce1811a739d4867e52c7850ed6e558cd 489 Pfam PF00575 S1 RNA binding domain 38 109 5.3E-6 T 29-03-2018 IPR003029 S1 domain GO:0003676 MC49_RS01660 ce1811a739d4867e52c7850ed6e558cd 489 SUPERFAMILY SSF50249 39 128 1.26E-18 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS01660 ce1811a739d4867e52c7850ed6e558cd 489 SMART SM00316 37 122 1.4E-8 T 29-03-2018 IPR022967 RNA-binding domain, S1 MC49_RS01660 ce1811a739d4867e52c7850ed6e558cd 489 Gene3D G3DSA:2.40.50.140 32 127 5.2E-30 T 29-03-2018 MC49_RS05750 ee608d2fcdd281d1feba5ceceaac7fd9 379 SUPERFAMILY SSF53383 19 378 6.19E-92 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS05750 ee608d2fcdd281d1feba5ceceaac7fd9 379 Gene3D G3DSA:3.90.1150.10 269 379 1.0E-24 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS05750 ee608d2fcdd281d1feba5ceceaac7fd9 379 Gene3D G3DSA:3.40.640.10 28 268 1.9E-39 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS05750 ee608d2fcdd281d1feba5ceceaac7fd9 379 PIRSF PIRSF000390 15 379 2.1E-86 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase MC49_RS05750 ee608d2fcdd281d1feba5ceceaac7fd9 379 TIGRFAM TIGR04181 NHT_00031: aminotransferase, LLPSF_NHT_00031 family 20 376 2.2E-163 T 29-03-2018 IPR026385 Aminotransferase, LLPSF_NHT_00031 family MC49_RS05750 ee608d2fcdd281d1feba5ceceaac7fd9 379 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 30 378 5.1E-80 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase MC49_RS19155 90c336e4082305e9b04b71385064fce0 363 SUPERFAMILY SSF53613 60 359 3.9E-60 T 29-03-2018 IPR029056 Ribokinase-like MC49_RS19155 90c336e4082305e9b04b71385064fce0 363 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 303 316 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MC49_RS19155 90c336e4082305e9b04b71385064fce0 363 Gene3D G3DSA:1.10.10.10 1 59 2.0E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS19155 90c336e4082305e9b04b71385064fce0 363 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 93 117 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MC49_RS19155 90c336e4082305e9b04b71385064fce0 363 Gene3D G3DSA:3.40.1190.20 60 363 1.4E-54 T 29-03-2018 IPR029056 Ribokinase-like MC49_RS19155 90c336e4082305e9b04b71385064fce0 363 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 48 3.9E-12 T 29-03-2018 MC49_RS19155 90c336e4082305e9b04b71385064fce0 363 SUPERFAMILY SSF46785 2 54 1.04E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS19155 90c336e4082305e9b04b71385064fce0 363 Pfam PF00294 pfkB family carbohydrate kinase 59 348 8.5E-62 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB MC49_RS06470 b6359566fb5aa3980f97addb05b6ff5b 252 Pfam PF00899 ThiF family 10 242 2.7E-64 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MC49_RS06470 b6359566fb5aa3980f97addb05b6ff5b 252 SUPERFAMILY SSF69572 2 245 4.32E-81 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MC49_RS06470 b6359566fb5aa3980f97addb05b6ff5b 252 Gene3D G3DSA:3.40.50.720 1 247 1.2E-71 T 29-03-2018 MC49_RS03445 db51a7f0b03d0524434c4c86395915f1 85 Pfam PF01016 Ribosomal L27 protein 2 82 2.4E-39 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS03445 db51a7f0b03d0524434c4c86395915f1 85 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 71 5.0E-18 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS03445 db51a7f0b03d0524434c4c86395915f1 85 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 85 29.38 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS03445 db51a7f0b03d0524434c4c86395915f1 85 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 82 6.9E-44 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS03445 db51a7f0b03d0524434c4c86395915f1 85 Gene3D G3DSA:2.40.50.100 20 84 3.6E-31 T 29-03-2018 MC49_RS03445 db51a7f0b03d0524434c4c86395915f1 85 SUPERFAMILY SSF110324 2 79 3.49E-34 T 29-03-2018 MC49_RS03445 db51a7f0b03d0524434c4c86395915f1 85 PRINTS PR00063 Ribosomal protein L27 signature 29 53 2.6E-39 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS03445 db51a7f0b03d0524434c4c86395915f1 85 PRINTS PR00063 Ribosomal protein L27 signature 54 78 2.6E-39 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS03445 db51a7f0b03d0524434c4c86395915f1 85 PRINTS PR00063 Ribosomal protein L27 signature 4 28 2.6E-39 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS03445 db51a7f0b03d0524434c4c86395915f1 85 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 29-03-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS03230 055a2522d5458383dd25acbf8af4bc49 169 SUPERFAMILY SSF55729 4 147 1.29E-29 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS03230 055a2522d5458383dd25acbf8af4bc49 169 Gene3D G3DSA:3.40.630.30 1 149 4.2E-27 T 29-03-2018 MC49_RS03230 055a2522d5458383dd25acbf8af4bc49 169 Pfam PF00583 Acetyltransferase (GNAT) family 53 144 5.6E-16 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MC49_RS04985 bf4765b683c552d5771dd18141372b90 208 ProSitePatterns PS01081 TetR-type HTH domain signature. 22 53 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MC49_RS04985 bf4765b683c552d5771dd18141372b90 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 5.2E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS04985 bf4765b683c552d5771dd18141372b90 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 5.2E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS04985 bf4765b683c552d5771dd18141372b90 208 SUPERFAMILY SSF46689 6 68 2.69E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS04985 bf4765b683c552d5771dd18141372b90 208 SUPERFAMILY SSF48498 70 205 2.22E-38 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MC49_RS04985 bf4765b683c552d5771dd18141372b90 208 Gene3D G3DSA:1.10.10.60 2 67 1.1E-14 T 29-03-2018 MC49_RS04985 bf4765b683c552d5771dd18141372b90 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 56 1.0E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS04985 bf4765b683c552d5771dd18141372b90 208 PRINTS PR00400 Tetracycline repressor protein signature 96 119 8.8E-55 T 29-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 MC49_RS04985 bf4765b683c552d5771dd18141372b90 208 PRINTS PR00400 Tetracycline repressor protein signature 184 198 8.8E-55 T 29-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 MC49_RS04985 bf4765b683c552d5771dd18141372b90 208 PRINTS PR00400 Tetracycline repressor protein signature 76 95 8.8E-55 T 29-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 MC49_RS04985 bf4765b683c552d5771dd18141372b90 208 PRINTS PR00400 Tetracycline repressor protein signature 22 45 8.8E-55 T 29-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 MC49_RS04985 bf4765b683c552d5771dd18141372b90 208 PRINTS PR00400 Tetracycline repressor protein signature 131 150 8.8E-55 T 29-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 MC49_RS04985 bf4765b683c552d5771dd18141372b90 208 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 70 202 2.8E-37 T 29-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 MC49_RS04985 bf4765b683c552d5771dd18141372b90 208 Gene3D G3DSA:1.10.357.10 68 207 1.3E-20 T 29-03-2018 MC49_RS17500 b754844fc99373653e43cc6d6cffc099 390 Pfam PF17482 Phage tail sheath C-terminal domain 275 377 1.7E-15 T 29-03-2018 IPR020287 Tail sheath protein, C-terminal domain MC49_RS17500 b754844fc99373653e43cc6d6cffc099 390 Pfam PF04984 Phage tail sheath protein subtilisin-like domain 108 274 2.6E-28 T 29-03-2018 IPR035089 Tail sheath protein, subtilisin-like domain MC49_RS08875 40bca5135d49ee416c9913247daaab29 448 PIRSF PIRSF006603 2 447 1.1E-71 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MC49_RS08875 40bca5135d49ee416c9913247daaab29 448 Pfam PF01554 MatE 17 176 1.6E-32 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MC49_RS08875 40bca5135d49ee416c9913247daaab29 448 Pfam PF01554 MatE 242 403 2.3E-26 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MC49_RS08875 40bca5135d49ee416c9913247daaab29 448 TIGRFAM TIGR00797 matE: MATE efflux family protein 17 416 5.3E-63 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MC49_RS04835 52fce4ff1ac0b3cb5d71de4f53b877e6 116 Gene3D G3DSA:1.10.260.40 13 111 9.1E-15 T 29-03-2018 MC49_RS04835 52fce4ff1ac0b3cb5d71de4f53b877e6 116 SUPERFAMILY SSF47413 21 82 7.51E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS04835 52fce4ff1ac0b3cb5d71de4f53b877e6 116 SMART SM00530 25 80 3.6E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS04835 52fce4ff1ac0b3cb5d71de4f53b877e6 116 Pfam PF01381 Helix-turn-helix 28 76 4.3E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS04400 e75d4c7522e4368cf4e1af2be32c9b58 256 TIGRFAM TIGR01738 bioH: pimelyl-[acyl-carrier protein] methyl ester esterase 10 255 2.4E-96 T 29-03-2018 IPR010076 Pimeloyl-[acyl-carrier protein] methyl ester esterase GO:0009102|GO:0052689 KEGG: 00780+3.1.1.85|MetaCyc: PWY-6519 MC49_RS04400 e75d4c7522e4368cf4e1af2be32c9b58 256 Gene3D G3DSA:3.40.50.1820 1 256 1.5E-46 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS04400 e75d4c7522e4368cf4e1af2be32c9b58 256 Hamap MF_01260 Pimeloyl-[acyl-carrier protein] methyl ester esterase [bioH]. 4 256 46.411 T 29-03-2018 IPR010076 Pimeloyl-[acyl-carrier protein] methyl ester esterase GO:0009102|GO:0052689 KEGG: 00780+3.1.1.85|MetaCyc: PWY-6519 MC49_RS04400 e75d4c7522e4368cf4e1af2be32c9b58 256 SUPERFAMILY SSF53474 3 255 6.62E-46 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS04400 e75d4c7522e4368cf4e1af2be32c9b58 256 Pfam PF00561 alpha/beta hydrolase fold 16 244 7.1E-16 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MC49_RS15450 ae0763d5e1a0f652c27934172dd5c269 252 Gene3D G3DSA:2.40.160.20 23 252 3.2E-12 T 29-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 MC49_RS15450 ae0763d5e1a0f652c27934172dd5c269 252 Pfam PF06629 MltA-interacting protein MipA 30 252 2.0E-54 T 29-03-2018 IPR010583 MltA-interacting MipA MC49_RS07140 6d3edbf0a1f7fc68bc67529a98c25fd2 490 Hamap MF_01636 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [ubiD]. 1 487 73.276 T 29-03-2018 IPR023677 UbiD decarboxylyase, bacteria GO:0005886|GO:0006744|GO:0008694 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 MC49_RS07140 6d3edbf0a1f7fc68bc67529a98c25fd2 490 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 455 9.7E-185 T 29-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 MC49_RS07140 6d3edbf0a1f7fc68bc67529a98c25fd2 490 Gene3D G3DSA:1.20.5.570 460 487 1.0E-17 T 29-03-2018 MC49_RS07140 6d3edbf0a1f7fc68bc67529a98c25fd2 490 SUPERFAMILY SSF50475 3 322 2.9E-129 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MC49_RS07140 6d3edbf0a1f7fc68bc67529a98c25fd2 490 SUPERFAMILY SSF143968 323 485 1.03E-66 T 29-03-2018 MC49_RS07140 6d3edbf0a1f7fc68bc67529a98c25fd2 490 Gene3D G3DSA:3.40.1670.10 323 459 2.1E-50 T 29-03-2018 MC49_RS07140 6d3edbf0a1f7fc68bc67529a98c25fd2 490 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 12 431 1.7E-171 T 29-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 MC49_RS00410 1c22621d7ee099a4db927882969a64cb 179 Pfam PF05869 DNA N-6-adenine-methyltransferase (Dam) 8 175 3.1E-75 T 29-03-2018 IPR008593 DNA N-6-adenine-methyltransferase GO:0003677|GO:0009007|GO:0032775 MC49_RS00410 1c22621d7ee099a4db927882969a64cb 179 TIGRFAM TIGR01712 phage_N6A_met: phage N-6-adenine-methyltransferase 7 171 4.2E-60 T 29-03-2018 IPR008593 DNA N-6-adenine-methyltransferase GO:0003677|GO:0009007|GO:0032775 MC49_RS00410 1c22621d7ee099a4db927882969a64cb 179 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 68 74 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MC49_RS10420 74c92019854974011f0048137b6a818d 297 Pfam PF03466 LysR substrate binding domain 89 285 2.5E-31 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS10420 74c92019854974011f0048137b6a818d 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 1.9E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS10420 74c92019854974011f0048137b6a818d 297 Gene3D G3DSA:1.10.10.10 3 85 3.7E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS10420 74c92019854974011f0048137b6a818d 297 Gene3D G3DSA:3.40.190.10 178 256 2.5E-10 T 29-03-2018 MC49_RS10420 74c92019854974011f0048137b6a818d 297 Gene3D G3DSA:3.40.190.10 90 177 1.7E-10 T 29-03-2018 MC49_RS10420 74c92019854974011f0048137b6a818d 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 6.7E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS10420 74c92019854974011f0048137b6a818d 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 6.7E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS10420 74c92019854974011f0048137b6a818d 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 6.7E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS10420 74c92019854974011f0048137b6a818d 297 SUPERFAMILY SSF53850 89 290 2.53E-31 T 29-03-2018 MC49_RS10420 74c92019854974011f0048137b6a818d 297 SUPERFAMILY SSF46785 6 112 1.74E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS07790 16cec4adaed184163871ccbd8483e738 270 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 9 265 55.884 T 29-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 MC49_RS07790 16cec4adaed184163871ccbd8483e738 270 Pfam PF00398 Ribosomal RNA adenine dimethylase 11 265 8.0E-80 T 29-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm MC49_RS07790 16cec4adaed184163871ccbd8483e738 270 SMART SM00650 25 198 3.3E-83 T 29-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 MC49_RS07790 16cec4adaed184163871ccbd8483e738 270 SUPERFAMILY SSF53335 5 267 1.47E-77 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS07790 16cec4adaed184163871ccbd8483e738 270 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 11 264 1.2E-88 T 29-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 MC49_RS07790 16cec4adaed184163871ccbd8483e738 270 Gene3D G3DSA:3.40.50.150 2 205 1.3E-54 T 29-03-2018 MC49_RS07790 16cec4adaed184163871ccbd8483e738 270 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 41 68 - T 29-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 MC49_RS07790 16cec4adaed184163871ccbd8483e738 270 Gene3D G3DSA:1.10.8.100 206 269 1.6E-18 T 29-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 MC49_RS14190 8b8aa9f4b8e2b2348758110047f24be1 520 Gene3D G3DSA:3.40.50.300 8 262 6.8E-52 T 29-03-2018 MC49_RS14190 8b8aa9f4b8e2b2348758110047f24be1 520 ProSitePatterns PS00211 ABC transporters family signature. 404 418 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS14190 8b8aa9f4b8e2b2348758110047f24be1 520 SMART SM00382 288 480 2.6E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS14190 8b8aa9f4b8e2b2348758110047f24be1 520 SMART SM00382 36 217 1.9E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS14190 8b8aa9f4b8e2b2348758110047f24be1 520 SUPERFAMILY SSF52540 279 496 2.83E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS14190 8b8aa9f4b8e2b2348758110047f24be1 520 Gene3D G3DSA:3.40.50.300 263 499 3.5E-39 T 29-03-2018 MC49_RS14190 8b8aa9f4b8e2b2348758110047f24be1 520 SUPERFAMILY SSF52540 10 229 1.09E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS14190 8b8aa9f4b8e2b2348758110047f24be1 520 Pfam PF00005 ABC transporter 280 431 1.2E-19 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS14190 8b8aa9f4b8e2b2348758110047f24be1 520 Pfam PF00005 ABC transporter 27 169 1.4E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS06245 68cc682b3ed2794f92009b865e8b90ab 170 Hamap MF_00163 Peptide deformylase [def]. 2 162 29.317 T 29-03-2018 IPR023635 Peptide deformylase MC49_RS06245 68cc682b3ed2794f92009b865e8b90ab 170 SUPERFAMILY SSF56420 3 165 5.89E-61 T 29-03-2018 IPR023635 Peptide deformylase MC49_RS06245 68cc682b3ed2794f92009b865e8b90ab 170 PIRSF PIRSF004749 1 170 7.5E-56 T 29-03-2018 IPR023635 Peptide deformylase MC49_RS06245 68cc682b3ed2794f92009b865e8b90ab 170 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 8 160 1.7E-54 T 29-03-2018 IPR023635 Peptide deformylase MC49_RS06245 68cc682b3ed2794f92009b865e8b90ab 170 Gene3D G3DSA:3.90.45.10 4 170 1.8E-59 T 29-03-2018 IPR023635 Peptide deformylase MC49_RS06245 68cc682b3ed2794f92009b865e8b90ab 170 Pfam PF01327 Polypeptide deformylase 8 152 1.5E-49 T 29-03-2018 IPR023635 Peptide deformylase MC49_RS06245 68cc682b3ed2794f92009b865e8b90ab 170 PRINTS PR01576 Peptide deformylase signature 33 62 2.2E-34 T 29-03-2018 IPR023635 Peptide deformylase MC49_RS06245 68cc682b3ed2794f92009b865e8b90ab 170 PRINTS PR01576 Peptide deformylase signature 89 100 2.2E-34 T 29-03-2018 IPR023635 Peptide deformylase MC49_RS06245 68cc682b3ed2794f92009b865e8b90ab 170 PRINTS PR01576 Peptide deformylase signature 101 119 2.2E-34 T 29-03-2018 IPR023635 Peptide deformylase MC49_RS06245 68cc682b3ed2794f92009b865e8b90ab 170 PRINTS PR01576 Peptide deformylase signature 120 149 2.2E-34 T 29-03-2018 IPR023635 Peptide deformylase MC49_RS08075 9ac398e7424e2657953b6898b24aec82 155 PIRSF PIRSF002094 1 155 3.4E-50 T 29-03-2018 IPR005632 Chaperone protein Skp GO:0051082 MC49_RS08075 9ac398e7424e2657953b6898b24aec82 155 Gene3D G3DSA:3.30.910.20 1 73 5.6E-13 T 29-03-2018 MC49_RS08075 9ac398e7424e2657953b6898b24aec82 155 Gene3D G3DSA:3.30.910.20 74 155 2.0E-18 T 29-03-2018 MC49_RS08075 9ac398e7424e2657953b6898b24aec82 155 Pfam PF03938 Outer membrane protein (OmpH-like) 2 153 9.2E-39 T 29-03-2018 IPR005632 Chaperone protein Skp GO:0051082 MC49_RS08075 9ac398e7424e2657953b6898b24aec82 155 SMART SM00935 1 155 8.8E-54 T 29-03-2018 IPR005632 Chaperone protein Skp GO:0051082 MC49_RS08075 9ac398e7424e2657953b6898b24aec82 155 SUPERFAMILY SSF111384 12 154 8.63E-38 T 29-03-2018 IPR024930 Skp domain MC49_RS13965 db2ac8540729a3df21065271c35ed6e9 313 SUPERFAMILY SSF51735 100 279 7.14E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS13965 db2ac8540729a3df21065271c35ed6e9 313 Gene3D G3DSA:3.40.50.720 184 313 1.7E-29 T 29-03-2018 MC49_RS13965 db2ac8540729a3df21065271c35ed6e9 313 Gene3D G3DSA:3.40.50.720 2 134 1.1E-9 T 29-03-2018 MC49_RS13965 db2ac8540729a3df21065271c35ed6e9 313 Gene3D G3DSA:3.40.50.720 138 183 2.1E-5 T 29-03-2018 MC49_RS13965 db2ac8540729a3df21065271c35ed6e9 313 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 108 278 1.1E-44 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MC49_RS13965 db2ac8540729a3df21065271c35ed6e9 313 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 217 233 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site MC49_RS19165 c5d68ea2c31cbdd66ead11d826bc7f6b 41 SUPERFAMILY SSF57840 7 41 3.01E-14 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS19165 c5d68ea2c31cbdd66ead11d826bc7f6b 41 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 17 41 0.002 T 29-03-2018 MC49_RS19165 c5d68ea2c31cbdd66ead11d826bc7f6b 41 ProSitePatterns PS00828 Ribosomal protein L36 signature. 14 40 - T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS19165 c5d68ea2c31cbdd66ead11d826bc7f6b 41 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 41 17.073 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS19165 c5d68ea2c31cbdd66ead11d826bc7f6b 41 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 9 41 6.1E-9 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS19165 c5d68ea2c31cbdd66ead11d826bc7f6b 41 Pfam PF00444 Ribosomal protein L36 1 41 2.2E-17 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS15475 42204de2768b5c0986327bef19596d5c 237 SMART SM00345 12 71 2.1E-22 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MC49_RS15475 42204de2768b5c0986327bef19596d5c 237 Gene3D G3DSA:1.20.120.530 80 237 9.4E-19 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MC49_RS15475 42204de2768b5c0986327bef19596d5c 237 TIGRFAM TIGR02812 fadR_gamma: fatty acid metabolism transcriptional regulator FadR 2 234 2.7E-121 T 29-03-2018 IPR014178 Fatty acid response transcription factor FadR GO:0000062|GO:0003677|GO:0003700|GO:0019217 MC49_RS15475 42204de2768b5c0986327bef19596d5c 237 SUPERFAMILY SSF48008 79 229 4.58E-64 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MC49_RS15475 42204de2768b5c0986327bef19596d5c 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 2.7E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MC49_RS15475 42204de2768b5c0986327bef19596d5c 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 2.7E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MC49_RS15475 42204de2768b5c0986327bef19596d5c 237 Pfam PF07840 FadR C-terminal domain 72 234 2.6E-72 T 29-03-2018 IPR028374 FadR, C-terminal domain GO:0000062|GO:0019217 MC49_RS15475 42204de2768b5c0986327bef19596d5c 237 Gene3D G3DSA:1.10.10.10 1 79 2.0E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS15475 42204de2768b5c0986327bef19596d5c 237 SUPERFAMILY SSF46785 11 88 7.61E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS15475 42204de2768b5c0986327bef19596d5c 237 Hamap MF_00696 Fatty acid metabolism regulator protein [fadR]. 1 237 155.633 T 29-03-2018 IPR014178 Fatty acid response transcription factor FadR GO:0000062|GO:0003677|GO:0003700|GO:0019217 MC49_RS15475 42204de2768b5c0986327bef19596d5c 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 71 9.7E-20 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MC49_RS01595 2d025d2e782a8161f89e05ab269556b0 155 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 16 154 3.3E-35 T 29-03-2018 IPR002178 PTS EIIA type-2 domain MC49_RS01595 2d025d2e782a8161f89e05ab269556b0 155 TIGRFAM TIGR01419 nitro_reg_IIA: PTS IIA-like nitrogen-regulatory protein PtsN 9 155 4.0E-53 T 29-03-2018 IPR006320 Phosphotransferase system, IIA-like nitrogen-regulatory protein PtsN GO:0008982|GO:0009401 MC49_RS01595 2d025d2e782a8161f89e05ab269556b0 155 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 57 73 - T 29-03-2018 IPR002178 PTS EIIA type-2 domain MC49_RS01595 2d025d2e782a8161f89e05ab269556b0 155 SUPERFAMILY SSF55804 9 155 1.83E-37 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 MC49_RS01595 2d025d2e782a8161f89e05ab269556b0 155 Gene3D G3DSA:3.40.930.10 7 155 5.9E-34 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 MC49_RS16005 b9c9a1a71d1a90788fbae7338551af7a 294 SMART SM00382 35 251 2.4E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS16005 b9c9a1a71d1a90788fbae7338551af7a 294 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS16005 b9c9a1a71d1a90788fbae7338551af7a 294 Gene3D G3DSA:3.40.50.300 2 245 2.2E-56 T 29-03-2018 MC49_RS16005 b9c9a1a71d1a90788fbae7338551af7a 294 Pfam PF00005 ABC transporter 28 173 3.4E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS16005 b9c9a1a71d1a90788fbae7338551af7a 294 SUPERFAMILY SSF52540 6 232 7.27E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS04595 24f4029fca0a7c3ab500d3c1b1e75449 189 SUPERFAMILY SSF49401 30 189 1.04E-21 T 29-03-2018 IPR008966 Adhesion domain MC49_RS04595 24f4029fca0a7c3ab500d3c1b1e75449 189 Gene3D G3DSA:2.60.40.1090 29 189 8.0E-26 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS04595 24f4029fca0a7c3ab500d3c1b1e75449 189 Pfam PF00419 Fimbrial protein 32 188 6.5E-10 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS14070 1ff9fc6880fc368d5bbe89d03dac0d0a 250 SUPERFAMILY SSF52317 2 195 5.33E-34 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MC49_RS14070 1ff9fc6880fc368d5bbe89d03dac0d0a 250 Gene3D G3DSA:3.40.50.880 1 236 7.0E-40 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MC49_RS14070 1ff9fc6880fc368d5bbe89d03dac0d0a 250 Pfam PF00117 Glutamine amidotransferase class-I 22 184 7.8E-16 T 29-03-2018 IPR017926 Glutamine amidotransferase MC49_RS10540 1ea71fcff76d6b852211ae9c2bc8da26 256 PIRSF PIRSF004846 1 256 1.2E-76 T 29-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 MC49_RS10540 1ea71fcff76d6b852211ae9c2bc8da26 256 Pfam PF13531 Bacterial extracellular solute-binding protein 28 253 4.5E-49 T 29-03-2018 MC49_RS10540 1ea71fcff76d6b852211ae9c2bc8da26 256 SUPERFAMILY SSF53850 26 255 5.56E-72 T 29-03-2018 MC49_RS10540 1ea71fcff76d6b852211ae9c2bc8da26 256 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 33 252 3.3E-78 T 29-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 MC49_RS10540 1ea71fcff76d6b852211ae9c2bc8da26 256 Gene3D G3DSA:3.40.190.10 25 120 1.1E-15 T 29-03-2018 MC49_RS10540 1ea71fcff76d6b852211ae9c2bc8da26 256 Gene3D G3DSA:3.40.190.10 121 217 9.8E-33 T 29-03-2018 MC49_RS16555 f2d6921178431654f08b99134dca4792 609 Gene3D G3DSA:3.30.70.1450 216 305 4.7E-13 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MC49_RS16555 f2d6921178431654f08b99134dca4792 609 Pfam PF03600 Citrate transporter 16 554 1.1E-51 T 29-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 MC49_RS16555 f2d6921178431654f08b99134dca4792 609 ProSitePatterns PS01271 Sodium:sulfate symporter family signature. 557 573 - T 29-03-2018 IPR031312 Sodium/sulphate symporter, conserved site Reactome: R-HSA-433137 MC49_RS16555 f2d6921178431654f08b99134dca4792 609 Gene3D G3DSA:3.30.70.1450 321 397 3.1E-16 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MC49_RS16555 f2d6921178431654f08b99134dca4792 609 SUPERFAMILY SSF116726 230 291 3.14E-10 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MC49_RS16555 f2d6921178431654f08b99134dca4792 609 SUPERFAMILY SSF116726 319 393 4.45E-17 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MC49_RS16555 f2d6921178431654f08b99134dca4792 609 Pfam PF02080 TrkA-C domain 230 301 6.0E-16 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MC49_RS16555 f2d6921178431654f08b99134dca4792 609 Pfam PF02080 TrkA-C domain 325 389 1.6E-11 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MC49_RS00750 92f738b993902cc2118eb101aa0facce 206 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 103 114 - T 29-03-2018 IPR018215 ClpP, Ser active site MC49_RS00750 92f738b993902cc2118eb101aa0facce 206 Gene3D G3DSA:3.90.226.10 15 206 1.0E-47 T 29-03-2018 MC49_RS00750 92f738b993902cc2118eb101aa0facce 206 Pfam PF00574 Clp protease 25 205 4.4E-89 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA MC49_RS00750 92f738b993902cc2118eb101aa0facce 206 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 125 138 - T 29-03-2018 IPR033135 ClpP, histidine active site MC49_RS00750 92f738b993902cc2118eb101aa0facce 206 SUPERFAMILY SSF52096 23 205 3.08E-74 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MC49_RS00750 92f738b993902cc2118eb101aa0facce 206 PRINTS PR00127 Clp protease catalytic subunit P signature 181 200 1.4E-53 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MC49_RS00750 92f738b993902cc2118eb101aa0facce 206 PRINTS PR00127 Clp protease catalytic subunit P signature 72 92 1.4E-53 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MC49_RS00750 92f738b993902cc2118eb101aa0facce 206 PRINTS PR00127 Clp protease catalytic subunit P signature 103 120 1.4E-53 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MC49_RS00750 92f738b993902cc2118eb101aa0facce 206 PRINTS PR00127 Clp protease catalytic subunit P signature 124 143 1.4E-53 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MC49_RS00750 92f738b993902cc2118eb101aa0facce 206 PRINTS PR00127 Clp protease catalytic subunit P signature 32 47 1.4E-53 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MC49_RS00750 92f738b993902cc2118eb101aa0facce 206 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 14 204 7.6E-109 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MC49_RS00750 92f738b993902cc2118eb101aa0facce 206 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 16 206 44.124 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MC49_RS15080 72428e08002cfcb44f5c7d43944c720e 101 Hamap MF_01948 Lipopolysaccharide assembly protein A [lapA]. 1 94 22.013 T 29-03-2018 IPR032906 Lipopolysaccharide assembly protein A GO:0005886|GO:0008653 MC49_RS15080 72428e08002cfcb44f5c7d43944c720e 101 Gene3D G3DSA:1.20.1070.10 1 100 9.5E-4 T 29-03-2018 MC49_RS15080 72428e08002cfcb44f5c7d43944c720e 101 Pfam PF06305 Lipopolysaccharide assembly protein A domain 23 85 3.2E-22 T 29-03-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 MC49_RS11920 2b6cbece17bbffc8e037a200d15824e9 240 TIGRFAM TIGR03349 IV_VI_DotU: type IV/VI secretion system protein, DotU family 15 225 2.7E-57 T 29-03-2018 IPR017732 Type IV / VI secretion system, DotU MC49_RS11920 2b6cbece17bbffc8e037a200d15824e9 240 Pfam PF09850 Type VI secretion system protein DotU 16 216 1.1E-54 T 29-03-2018 IPR017732 Type IV / VI secretion system, DotU MC49_RS12575 65514a91dc4dc3008dbfa1067a21ea4f 245 SUPERFAMILY SSF51735 5 242 1.2E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS12575 65514a91dc4dc3008dbfa1067a21ea4f 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 241 3.9E-37 T 29-03-2018 MC49_RS12575 65514a91dc4dc3008dbfa1067a21ea4f 245 Gene3D G3DSA:3.40.50.720 2 241 2.3E-42 T 29-03-2018 MC49_RS12575 65514a91dc4dc3008dbfa1067a21ea4f 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.5E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS12575 65514a91dc4dc3008dbfa1067a21ea4f 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.5E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS12575 65514a91dc4dc3008dbfa1067a21ea4f 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.5E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS12575 65514a91dc4dc3008dbfa1067a21ea4f 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.5E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS12575 65514a91dc4dc3008dbfa1067a21ea4f 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.5E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS12575 65514a91dc4dc3008dbfa1067a21ea4f 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 1.5E-26 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS06920 2e3d7147bd783343e19975b430f87349 242 Gene3D G3DSA:3.40.140.10 2 104 3.3E-15 T 29-03-2018 MC49_RS06920 2e3d7147bd783343e19975b430f87349 242 Pfam PF14464 Prokaryotic homologs of the JAB domain 4 95 1.5E-15 T 29-03-2018 IPR028090 JAB domain, prokaryotic MC49_RS06920 2e3d7147bd783343e19975b430f87349 242 Gene3D G3DSA:3.90.1720.10 163 229 2.9E-4 T 29-03-2018 MC49_RS06920 2e3d7147bd783343e19975b430f87349 242 Pfam PF00877 NlpC/P60 family 109 221 1.7E-16 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain MC49_RS06920 2e3d7147bd783343e19975b430f87349 242 SMART SM00232 1 117 0.0021 T 29-03-2018 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 MC49_RS06920 2e3d7147bd783343e19975b430f87349 242 SUPERFAMILY SSF54001 106 225 2.16E-17 T 29-03-2018 MC49_RS06920 2e3d7147bd783343e19975b430f87349 242 SUPERFAMILY SSF102712 4 95 2.48E-16 T 29-03-2018 MC49_RS08465 5c267a7b5399933bef943bb01d610d0a 356 Pfam PF00155 Aminotransferase class I and II 22 349 5.0E-43 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MC49_RS08465 5c267a7b5399933bef943bb01d610d0a 356 TIGRFAM TIGR01140 L_thr_O3P_dcar: threonine-phosphate decarboxylase 4 350 4.5E-96 T 29-03-2018 IPR005860 L-threonine-O-3-phosphate decarboxylase GO:0003824|GO:0009236 KEGG: 00860+4.1.1.81|MetaCyc: PWY-5443 MC49_RS08465 5c267a7b5399933bef943bb01d610d0a 356 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 210 223 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 MC49_RS08465 5c267a7b5399933bef943bb01d610d0a 356 Gene3D G3DSA:3.40.640.10 34 245 3.5E-38 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS08465 5c267a7b5399933bef943bb01d610d0a 356 Gene3D G3DSA:3.90.1150.10 246 355 7.7E-18 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS08465 5c267a7b5399933bef943bb01d610d0a 356 Gene3D G3DSA:1.10.10.60 1 23 0.0027 T 29-03-2018 MC49_RS08465 5c267a7b5399933bef943bb01d610d0a 356 SUPERFAMILY SSF53383 3 352 1.51E-74 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS17935 8d6f9f45c38449183f633a2cfd10a425 154 Gene3D G3DSA:3.30.428.10 1 151 1.2E-24 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 MC49_RS17935 8d6f9f45c38449183f633a2cfd10a425 154 SUPERFAMILY SSF54197 1 112 3.56E-26 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 MC49_RS17935 8d6f9f45c38449183f633a2cfd10a425 154 PRINTS PR00332 Histidine triad family signature 4 20 1.6E-5 T 29-03-2018 IPR001310 Histidine triad (HIT) protein MC49_RS17935 8d6f9f45c38449183f633a2cfd10a425 154 PRINTS PR00332 Histidine triad family signature 25 43 1.6E-5 T 29-03-2018 IPR001310 Histidine triad (HIT) protein MC49_RS17935 8d6f9f45c38449183f633a2cfd10a425 154 Pfam PF01230 HIT domain 12 78 7.3E-10 T 29-03-2018 IPR001310 Histidine triad (HIT) protein MC49_RS08025 62b3626b6499920ae6ee18d3afb69a6f 265 Gene3D G3DSA:3.90.230.10 1 265 1.9E-84 T 29-03-2018 MC49_RS08025 62b3626b6499920ae6ee18d3afb69a6f 265 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 3 250 1.3E-104 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MC49_RS08025 62b3626b6499920ae6ee18d3afb69a6f 265 PRINTS PR00599 Methionine aminopeptidase-1 signature 69 82 1.3E-22 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MC49_RS08025 62b3626b6499920ae6ee18d3afb69a6f 265 PRINTS PR00599 Methionine aminopeptidase-1 signature 92 108 1.3E-22 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MC49_RS08025 62b3626b6499920ae6ee18d3afb69a6f 265 PRINTS PR00599 Methionine aminopeptidase-1 signature 193 205 1.3E-22 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MC49_RS08025 62b3626b6499920ae6ee18d3afb69a6f 265 PRINTS PR00599 Methionine aminopeptidase-1 signature 162 174 1.3E-22 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MC49_RS08025 62b3626b6499920ae6ee18d3afb69a6f 265 SUPERFAMILY SSF55920 3 253 1.96E-87 T 29-03-2018 IPR000994 Peptidase M24 MC49_RS08025 62b3626b6499920ae6ee18d3afb69a6f 265 Hamap MF_01974 Methionine aminopeptidase [map]. 3 251 42.415 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MC49_RS08025 62b3626b6499920ae6ee18d3afb69a6f 265 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 168 186 - T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MC49_RS08025 62b3626b6499920ae6ee18d3afb69a6f 265 Pfam PF00557 Metallopeptidase family M24 13 242 4.2E-50 T 29-03-2018 IPR000994 Peptidase M24 MC49_RS04695 44a7d247dfa641071e23026039bef9ad 318 Gene3D G3DSA:3.30.70.1070 236 309 4.4E-4 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 MC49_RS04695 44a7d247dfa641071e23026039bef9ad 318 SUPERFAMILY SSF110997 235 299 2.35E-6 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 MC49_RS04695 44a7d247dfa641071e23026039bef9ad 318 Pfam PF05036 Sporulation related domain 235 309 5.2E-11 T 29-03-2018 IPR007730 Sporulation-related domain GO:0042834 MC49_RS09280 291b00bb68459c8be8c76a7a41612cee 261 PIRSF PIRSF030802 2 258 3.6E-124 T 29-03-2018 IPR024197 Uncharacterised conserved protein UCP030802 MC49_RS09280 291b00bb68459c8be8c76a7a41612cee 261 Gene3D G3DSA:3.40.50.1000 5 258 7.2E-8 T 29-03-2018 IPR023214 HAD-like domain MC49_RS09280 291b00bb68459c8be8c76a7a41612cee 261 SUPERFAMILY SSF56784 6 235 4.03E-17 T 29-03-2018 IPR023214 HAD-like domain MC49_RS07065 b5ff0b9575ff405c569b315b429ba30a 761 PIRSF PIRSF000382 2 760 0.0 T 29-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MC49_RS07065 b5ff0b9575ff405c569b315b429ba30a 761 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 5 313 4.7E-123 T 29-03-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MC49_RS07065 b5ff0b9575ff405c569b315b429ba30a 761 Gene3D G3DSA:3.20.20.210 388 756 7.5E-127 T 29-03-2018 MC49_RS07065 b5ff0b9575ff405c569b315b429ba30a 761 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 8 755 0.0 T 29-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MC49_RS07065 b5ff0b9575ff405c569b315b429ba30a 761 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 3 756 37.323 T 29-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MC49_RS07065 b5ff0b9575ff405c569b315b429ba30a 761 SUPERFAMILY SSF51726 6 392 6.28E-116 T 29-03-2018 MC49_RS07065 b5ff0b9575ff405c569b315b429ba30a 761 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 429 751 2.5E-158 T 29-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MC49_RS07065 b5ff0b9575ff405c569b315b429ba30a 761 SUPERFAMILY SSF51726 394 755 3.79E-119 T 29-03-2018 MC49_RS07065 b5ff0b9575ff405c569b315b429ba30a 761 Gene3D G3DSA:3.20.20.210 3 387 7.6E-142 T 29-03-2018 MC49_RS11355 1a82a9d80dbe9f0a95877006a5c7d0d1 109 TIGRFAM TIGR03342 dsrC_tusE_dsvC: sulfur relay protein, TusE/DsrC/DsvC family 4 109 5.7E-50 T 29-03-2018 IPR007453 Sulphur transfer protein DsrC/TusE MC49_RS11355 1a82a9d80dbe9f0a95877006a5c7d0d1 109 PIRSF PIRSF006223 2 109 1.7E-44 T 29-03-2018 IPR007453 Sulphur transfer protein DsrC/TusE MC49_RS11355 1a82a9d80dbe9f0a95877006a5c7d0d1 109 Gene3D G3DSA:3.30.1420.10 2 39 6.2E-14 T 29-03-2018 MC49_RS11355 1a82a9d80dbe9f0a95877006a5c7d0d1 109 Pfam PF04358 DsrC like protein 4 109 3.1E-45 T 29-03-2018 IPR007453 Sulphur transfer protein DsrC/TusE MC49_RS11355 1a82a9d80dbe9f0a95877006a5c7d0d1 109 SUPERFAMILY SSF69721 2 109 6.54E-42 T 29-03-2018 IPR025526 DsrC-like domain MC49_RS11355 1a82a9d80dbe9f0a95877006a5c7d0d1 109 Gene3D G3DSA:1.10.10.370 40 108 3.4E-34 T 29-03-2018 MC49_RS00800 2dd8d87de73e3343f2cb85c7a8f2eba8 294 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 3 281 1.6E-91 T 29-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 MC49_RS00800 2dd8d87de73e3343f2cb85c7a8f2eba8 294 Pfam PF01040 UbiA prenyltransferase family 18 266 8.5E-58 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 MC49_RS00800 2dd8d87de73e3343f2cb85c7a8f2eba8 294 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 56 78 - T 29-03-2018 IPR030470 UbiA prenyltransferase conserved site MC49_RS00800 2dd8d87de73e3343f2cb85c7a8f2eba8 294 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 1 283 18.422 T 29-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 MC49_RS10700 1926caea3828c470870f71feba8ae344 299 Pfam PF00892 EamA-like transporter family 154 283 1.3E-13 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MC49_RS10700 1926caea3828c470870f71feba8ae344 299 SUPERFAMILY SSF103481 190 285 3.66E-8 T 29-03-2018 MC49_RS10700 1926caea3828c470870f71feba8ae344 299 SUPERFAMILY SSF103481 48 138 6.02E-6 T 29-03-2018 MC49_RS12540 2fa85d9faef09f148859d0cf997f82c2 260 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 29-03-2018 IPR019776 Flagellar basal body rod protein, conserved site MC49_RS12540 2fa85d9faef09f148859d0cf997f82c2 260 SUPERFAMILY SSF117143 92 222 1.44E-34 T 29-03-2018 MC49_RS12540 2fa85d9faef09f148859d0cf997f82c2 260 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 182 260 1.7E-26 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain MC49_RS12540 2fa85d9faef09f148859d0cf997f82c2 260 TIGRFAM TIGR02488 flgG_G_neg: flagellar basal-body rod protein FlgG 4 259 4.0E-115 T 29-03-2018 IPR012834 Flagellar basal-body rod FlgG GO:0009426|GO:0071973 MC49_RS12540 2fa85d9faef09f148859d0cf997f82c2 260 Pfam PF00460 Flagella basal body rod protein 5 35 1.4E-13 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 MC49_RS12540 2fa85d9faef09f148859d0cf997f82c2 260 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 144 243 1.0E-31 T 29-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G MC49_RS12540 2fa85d9faef09f148859d0cf997f82c2 260 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 136 9.9E-48 T 29-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G MC49_RS16345 d0b37ceee90048187efbd50b13554652 297 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 73 226 6.3E-52 T 29-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 MC49_RS16345 d0b37ceee90048187efbd50b13554652 297 Pfam PF00849 RNA pseudouridylate synthase 69 195 1.0E-13 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS16345 d0b37ceee90048187efbd50b13554652 297 SUPERFAMILY SSF55174 7 62 4.04E-13 T 29-03-2018 MC49_RS16345 d0b37ceee90048187efbd50b13554652 297 Gene3D G3DSA:3.10.290.10 4 63 8.6E-17 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MC49_RS16345 d0b37ceee90048187efbd50b13554652 297 Gene3D G3DSA:3.30.70.580 64 144 6.3E-16 T 29-03-2018 MC49_RS16345 d0b37ceee90048187efbd50b13554652 297 SUPERFAMILY SSF55120 69 229 1.32E-37 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS16345 d0b37ceee90048187efbd50b13554652 297 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 104 118 - T 29-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 MC49_RS16345 d0b37ceee90048187efbd50b13554652 297 Gene3D G3DSA:3.30.70.1560 145 212 8.5E-23 T 29-03-2018 MC49_RS16345 d0b37ceee90048187efbd50b13554652 297 SMART SM00363 7 63 2.2E-10 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MC49_RS16345 d0b37ceee90048187efbd50b13554652 297 Pfam PF01479 S4 domain 7 52 1.4E-10 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MC49_RS00020 ca9cc8b74cec9468f47026de615ed8b5 338 Gene3D G3DSA:3.90.180.10 273 334 9.8E-4 T 29-03-2018 MC49_RS00020 ca9cc8b74cec9468f47026de615ed8b5 338 Gene3D G3DSA:3.40.50.720 165 272 5.6E-21 T 29-03-2018 MC49_RS00020 ca9cc8b74cec9468f47026de615ed8b5 338 Gene3D G3DSA:3.90.180.10 1 164 3.4E-49 T 29-03-2018 MC49_RS00020 ca9cc8b74cec9468f47026de615ed8b5 338 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 57 71 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MC49_RS00020 ca9cc8b74cec9468f47026de615ed8b5 338 Pfam PF00107 Zinc-binding dehydrogenase 172 296 2.4E-25 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MC49_RS00020 ca9cc8b74cec9468f47026de615ed8b5 338 SMART SM00829 7 332 8.0E-6 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MC49_RS00020 ca9cc8b74cec9468f47026de615ed8b5 338 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 131 7.8E-27 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MC49_RS00020 ca9cc8b74cec9468f47026de615ed8b5 338 SUPERFAMILY SSF50129 1 169 4.26E-45 T 29-03-2018 IPR011032 GroES-like MC49_RS00020 ca9cc8b74cec9468f47026de615ed8b5 338 SUPERFAMILY SSF51735 135 302 9.08E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS13265 cd711a20631d49c939530a9e85e27394 91 Pfam PF14110 Domain of unknown function (DUF4282) 6 85 1.1E-14 T 29-03-2018 IPR025557 Protein of unknown function DUF4282 MC49_RS04160 1ccedeade7e2fda641ed19ffcaf25b8a 209 SUPERFAMILY SSF50447 1 208 9.71E-81 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain MC49_RS04160 1ccedeade7e2fda641ed19ffcaf25b8a 209 Pfam PF00297 Ribosomal protein L3 35 182 1.5E-15 T 29-03-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS04160 1ccedeade7e2fda641ed19ffcaf25b8a 209 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 3 204 3.9E-93 T 29-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS04160 1ccedeade7e2fda641ed19ffcaf25b8a 209 ProSitePatterns PS00474 Ribosomal protein L3 signature. 101 124 - T 29-03-2018 IPR019926 Ribosomal protein L3, conserved site MC49_RS04160 1ccedeade7e2fda641ed19ffcaf25b8a 209 Gene3D G3DSA:4.10.960.10 57 165 2.4E-36 T 29-03-2018 MC49_RS04160 1ccedeade7e2fda641ed19ffcaf25b8a 209 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 1 207 41.205 T 29-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS16760 6b25bef85fe35d7199da4b5537f7b43b 444 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 94 397 2.4E-59 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MC49_RS16760 6b25bef85fe35d7199da4b5537f7b43b 444 Gene3D G3DSA:3.40.50.1100 115 231 3.9E-25 T 29-03-2018 MC49_RS16760 6b25bef85fe35d7199da4b5537f7b43b 444 Hamap MF_01030 D-serine dehydratase [dsdA]. 1 444 266.334 T 29-03-2018 IPR011780 D-serine ammonia-lyase GO:0008721|GO:0030170|GO:0046416 KEGG: 00260+4.3.1.18 MC49_RS16760 6b25bef85fe35d7199da4b5537f7b43b 444 SUPERFAMILY SSF53686 95 438 4.12E-54 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MC49_RS16760 6b25bef85fe35d7199da4b5537f7b43b 444 TIGRFAM TIGR02035 D_Ser_am_lyase: D-serine ammonia-lyase 10 438 6.2E-224 T 29-03-2018 IPR011780 D-serine ammonia-lyase GO:0008721|GO:0030170|GO:0046416 KEGG: 00260+4.3.1.18 MC49_RS16760 6b25bef85fe35d7199da4b5537f7b43b 444 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 108 122 - T 29-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 MC49_RS16760 6b25bef85fe35d7199da4b5537f7b43b 444 Gene3D G3DSA:3.40.50.1100 232 441 1.1E-26 T 29-03-2018 MC49_RS14085 05a63943cf3caa785d9c90d10937debe 304 PRINTS PR00690 Adhesin family signature 57 70 1.1E-6 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 MC49_RS14085 05a63943cf3caa785d9c90d10937debe 304 PRINTS PR00690 Adhesin family signature 191 212 1.1E-6 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 MC49_RS14085 05a63943cf3caa785d9c90d10937debe 304 PRINTS PR00690 Adhesin family signature 70 87 1.1E-6 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 MC49_RS14085 05a63943cf3caa785d9c90d10937debe 304 Gene3D G3DSA:3.40.50.1980 28 184 2.1E-42 T 29-03-2018 MC49_RS14085 05a63943cf3caa785d9c90d10937debe 304 Gene3D G3DSA:3.40.50.1980 185 303 1.4E-22 T 29-03-2018 MC49_RS14085 05a63943cf3caa785d9c90d10937debe 304 Pfam PF01297 Zinc-uptake complex component A periplasmic 29 289 8.3E-54 T 29-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 MC49_RS14085 05a63943cf3caa785d9c90d10937debe 304 SUPERFAMILY SSF53807 19 302 1.86E-71 T 29-03-2018 MC49_RS13690 61ea5fba71c9c6ecc2ece2e878fefbd4 165 ProSitePatterns PS01320 Uncharacterized protein family UPF0067 signature. 90 107 - T 29-03-2018 IPR000614 Free Met sulfoxide reductase conserved site MC49_RS13690 61ea5fba71c9c6ecc2ece2e878fefbd4 165 Pfam PF13185 GAF domain 27 136 3.9E-11 T 29-03-2018 IPR003018 GAF domain GO:0005515 MC49_RS13690 61ea5fba71c9c6ecc2ece2e878fefbd4 165 Gene3D G3DSA:3.30.450.40 2 154 2.9E-24 T 29-03-2018 IPR029016 GAF domain-like MC49_RS13690 61ea5fba71c9c6ecc2ece2e878fefbd4 165 SMART SM00065 23 161 0.0035 T 29-03-2018 IPR003018 GAF domain GO:0005515 MC49_RS13690 61ea5fba71c9c6ecc2ece2e878fefbd4 165 SUPERFAMILY SSF55781 2 150 9.08E-42 T 29-03-2018 IPR029016 GAF domain-like MC49_RS14590 dc5f8febc982912ef9aa5ebb925aa3fe 362 Gene3D G3DSA:1.10.287.470 102 172 3.5E-4 T 29-03-2018 MC49_RS14590 dc5f8febc982912ef9aa5ebb925aa3fe 362 SUPERFAMILY SSF111369 43 267 2.09E-12 T 29-03-2018 MC49_RS14590 dc5f8febc982912ef9aa5ebb925aa3fe 362 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 63 267 7.0E-15 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MC49_RS14590 dc5f8febc982912ef9aa5ebb925aa3fe 362 Gene3D G3DSA:2.40.50.100 173 280 0.092 T 29-03-2018 MC49_RS14590 dc5f8febc982912ef9aa5ebb925aa3fe 362 Gene3D G3DSA:3.90.1170.30 22 101 2.2E-4 T 29-03-2018 MC49_RS14590 dc5f8febc982912ef9aa5ebb925aa3fe 362 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 41 357 9.8E-43 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MC49_RS05030 9d9bf764f782a7546aea7ddb1fad7bb3 644 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 490 517 2.9E-48 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS05030 9d9bf764f782a7546aea7ddb1fad7bb3 644 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 519 548 2.9E-48 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS05030 9d9bf764f782a7546aea7ddb1fad7bb3 644 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 413 442 2.9E-48 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS05030 9d9bf764f782a7546aea7ddb1fad7bb3 644 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 313 333 2.9E-48 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS05030 9d9bf764f782a7546aea7ddb1fad7bb3 644 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 567 596 2.9E-48 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS05030 9d9bf764f782a7546aea7ddb1fad7bb3 644 SUPERFAMILY SSF58104 359 640 4.97E-66 T 29-03-2018 MC49_RS05030 9d9bf764f782a7546aea7ddb1fad7bb3 644 SMART SM00304 337 391 1.3E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MC49_RS05030 9d9bf764f782a7546aea7ddb1fad7bb3 644 Pfam PF02743 Cache domain 104 298 3.5E-23 T 29-03-2018 IPR033479 Double Cache domain 1 MC49_RS05030 9d9bf764f782a7546aea7ddb1fad7bb3 644 Gene3D G3DSA:1.10.287.950 447 643 2.1E-43 T 29-03-2018 MC49_RS05030 9d9bf764f782a7546aea7ddb1fad7bb3 644 Gene3D G3DSA:1.10.287.950 335 446 1.5E-13 T 29-03-2018 MC49_RS05030 9d9bf764f782a7546aea7ddb1fad7bb3 644 Gene3D G3DSA:3.30.450.20 73 185 2.2E-16 T 29-03-2018 MC49_RS05030 9d9bf764f782a7546aea7ddb1fad7bb3 644 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 451 605 1.8E-47 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MC49_RS05030 9d9bf764f782a7546aea7ddb1fad7bb3 644 Pfam PF00672 HAMP domain 337 386 1.8E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MC49_RS05030 9d9bf764f782a7546aea7ddb1fad7bb3 644 SMART SM00283 392 639 8.7E-71 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MC49_RS05030 9d9bf764f782a7546aea7ddb1fad7bb3 644 Gene3D G3DSA:3.30.450.20 186 315 2.7E-19 T 29-03-2018 MC49_RS07305 08b0e9d9df3d15c4f4dd487332eb0513 354 Gene3D G3DSA:3.40.1090.10 19 257 1.1E-28 T 29-03-2018 MC49_RS07305 08b0e9d9df3d15c4f4dd487332eb0513 354 Pfam PF01734 Patatin-like phospholipase 30 199 5.3E-20 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 MC49_RS07305 08b0e9d9df3d15c4f4dd487332eb0513 354 SUPERFAMILY SSF52151 26 282 2.62E-43 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MC49_RS10985 4c4d25dda886b3d005395ec92cd402b3 234 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 6 81 4.1E-12 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 MC49_RS10985 4c4d25dda886b3d005395ec92cd402b3 234 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 26 227 3.3E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS10985 4c4d25dda886b3d005395ec92cd402b3 234 Gene3D G3DSA:1.10.3720.10 2 232 1.5E-35 T 29-03-2018 MC49_RS10985 4c4d25dda886b3d005395ec92cd402b3 234 SUPERFAMILY SSF161098 7 215 7.72E-36 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS07880 59833038e98d362e722ad0b859e9dce2 116 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 10 31 8.1E-5 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site MC49_RS07880 59833038e98d362e722ad0b859e9dce2 116 Pfam PF07963 Prokaryotic N-terminal methylation motif 7 32 8.5E-6 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site MC49_RS07880 59833038e98d362e722ad0b859e9dce2 116 Pfam PF12528 Type II secretion prepilin peptidase dependent protein C 34 116 3.9E-22 T 29-03-2018 IPR022204 Prepilin peptidase dependent protein C MC49_RS09485 aeadef23d109e824d2e4f166e489b50d 344 Pfam PF13343 Bacterial extracellular solute-binding protein 76 300 1.1E-19 T 29-03-2018 MC49_RS09485 aeadef23d109e824d2e4f166e489b50d 344 Gene3D G3DSA:3.40.190.10 28 145 5.2E-12 T 29-03-2018 MC49_RS09485 aeadef23d109e824d2e4f166e489b50d 344 PIRSF PIRSF002825 3 344 1.9E-84 T 29-03-2018 IPR026045 Ferric binding protein MC49_RS09485 aeadef23d109e824d2e4f166e489b50d 344 Gene3D G3DSA:3.40.190.10 146 289 7.7E-26 T 29-03-2018 MC49_RS09485 aeadef23d109e824d2e4f166e489b50d 344 SUPERFAMILY SSF53850 29 342 1.28E-70 T 29-03-2018 MC49_RS08090 38a929aa9672c272cc4a7074f65ff742 263 Gene3D G3DSA:2.160.10.10 1 196 1.3E-45 T 29-03-2018 MC49_RS08090 38a929aa9672c272cc4a7074f65ff742 263 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 8 260 6.3E-111 T 29-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 MC49_RS08090 38a929aa9672c272cc4a7074f65ff742 263 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 180 261 3.7E-27 T 29-03-2018 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 MC49_RS08090 38a929aa9672c272cc4a7074f65ff742 263 SUPERFAMILY SSF51161 1 262 1.7E-80 T 29-03-2018 IPR011004 Trimeric LpxA-like MC49_RS08090 38a929aa9672c272cc4a7074f65ff742 263 Gene3D G3DSA:1.20.1180.10 197 263 2.8E-23 T 29-03-2018 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 MC49_RS08090 38a929aa9672c272cc4a7074f65ff742 263 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 20 48 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MC49_RS08090 38a929aa9672c272cc4a7074f65ff742 263 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 109 142 2.2E-8 T 29-03-2018 IPR001451 Hexapeptide repeat MC49_RS08090 38a929aa9672c272cc4a7074f65ff742 263 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 17 52 4.3E-9 T 29-03-2018 IPR001451 Hexapeptide repeat MC49_RS08090 38a929aa9672c272cc4a7074f65ff742 263 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 153 181 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MC49_RS08090 38a929aa9672c272cc4a7074f65ff742 263 PIRSF PIRSF000456 4 263 1.2E-108 T 29-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 MC49_RS08090 38a929aa9672c272cc4a7074f65ff742 263 Hamap MF_00387 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [lpxA]. 5 262 48.341 T 29-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 MC49_RS16055 af066969eed48e937a75dd87994ddd11 759 ProSitePatterns PS00331 Malic enzymes signature. 159 175 - T 29-03-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 MC49_RS16055 af066969eed48e937a75dd87994ddd11 759 Pfam PF03949 Malic enzyme, NAD binding domain 165 362 5.0E-17 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 MC49_RS16055 af066969eed48e937a75dd87994ddd11 759 PIRSF PIRSF036684 1 758 0.0 T 29-03-2018 IPR012188 NAD(P)-dependent malic enzyme GO:0004470|GO:0006108|GO:0046872 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 MC49_RS16055 af066969eed48e937a75dd87994ddd11 759 Pfam PF00390 Malic enzyme, N-terminal domain 19 151 7.5E-27 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MC49_RS16055 af066969eed48e937a75dd87994ddd11 759 Gene3D G3DSA:3.40.50.720 161 446 5.6E-83 T 29-03-2018 MC49_RS16055 af066969eed48e937a75dd87994ddd11 759 SMART SM00919 163 401 7.4E-139 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 MC49_RS16055 af066969eed48e937a75dd87994ddd11 759 SUPERFAMILY SSF53223 11 161 1.22E-52 T 29-03-2018 MC49_RS16055 af066969eed48e937a75dd87994ddd11 759 SMART SM01274 18 151 1.2E-79 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MC49_RS16055 af066969eed48e937a75dd87994ddd11 759 Gene3D G3DSA:3.40.50.10380 5 160 4.5E-35 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MC49_RS16055 af066969eed48e937a75dd87994ddd11 759 Gene3D G3DSA:3.40.718.10 447 720 1.8E-48 T 29-03-2018 MC49_RS16055 af066969eed48e937a75dd87994ddd11 759 SUPERFAMILY SSF53659 430 754 4.52E-91 T 29-03-2018 MC49_RS16055 af066969eed48e937a75dd87994ddd11 759 Pfam PF01515 Phosphate acetyl/butaryl transferase 430 751 4.2E-98 T 29-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MC49_RS16055 af066969eed48e937a75dd87994ddd11 759 SUPERFAMILY SSF51735 163 453 8.01E-86 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS05115 bbb784b45deb3610aabaa7c3f1728c2a 330 Pfam PF03590 Aspartate-ammonia ligase 9 244 9.3E-96 T 29-03-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 MC49_RS05115 bbb784b45deb3610aabaa7c3f1728c2a 330 TIGRFAM TIGR00669 asnA: aspartate--ammonia ligase 1 330 2.9E-177 T 29-03-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 MC49_RS05115 bbb784b45deb3610aabaa7c3f1728c2a 330 SUPERFAMILY SSF55681 5 329 7.3E-99 T 29-03-2018 MC49_RS05115 bbb784b45deb3610aabaa7c3f1728c2a 330 PIRSF PIRSF001555 1 330 5.9E-150 T 29-03-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 MC49_RS05115 bbb784b45deb3610aabaa7c3f1728c2a 330 Gene3D G3DSA:3.30.930.10 1 316 5.4E-36 T 29-03-2018 MC49_RS05115 bbb784b45deb3610aabaa7c3f1728c2a 330 Hamap MF_00555 Aspartate--ammonia ligase [asnA]. 1 330 45.157 T 29-03-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 MC49_RS05990 0ffeea47be4ef975220f82d74c5621da 167 Hamap MF_01058 Der GTPase-activating protein YihI [yihI]. 1 167 16.019 T 29-03-2018 IPR007336 Der GTPase activator GO:0005096 MC49_RS05990 0ffeea47be4ef975220f82d74c5621da 167 Pfam PF04220 Der GTPase activator (YihI) 10 164 3.0E-54 T 29-03-2018 IPR007336 Der GTPase activator GO:0005096 MC49_RS11620 1de19dbda4e3a34e08b24de8ae74d79c 245 Pfam PF02811 PHP domain 5 81 1.9E-6 T 29-03-2018 IPR004013 PHP domain GO:0003824 MC49_RS11620 1de19dbda4e3a34e08b24de8ae74d79c 245 SMART SM00481 4 78 8.9E-13 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal MC49_RS11620 1de19dbda4e3a34e08b24de8ae74d79c 245 Hamap MF_01561 Probable phosphatase YcdX [ycdX]. 1 243 47.188 T 29-03-2018 IPR023710 Probable phosphatase YcdX GO:0008270 MC49_RS11620 1de19dbda4e3a34e08b24de8ae74d79c 245 SUPERFAMILY SSF89550 3 241 7.06E-59 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 MC49_RS11620 1de19dbda4e3a34e08b24de8ae74d79c 245 Gene3D G3DSA:3.20.20.140 6 229 6.1E-37 T 29-03-2018 MC49_RS16530 a52abd6d2bba12bbef1c238072307a48 224 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 46 182 1.6E-69 T 29-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16530 a52abd6d2bba12bbef1c238072307a48 224 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 148 164 - T 29-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16530 a52abd6d2bba12bbef1c238072307a48 224 Gene3D G3DSA:3.40.50.700 36 210 6.3E-39 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16530 a52abd6d2bba12bbef1c238072307a48 224 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 68 174 3.4E-22 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16530 a52abd6d2bba12bbef1c238072307a48 224 SUPERFAMILY SSF56770 43 189 2.35E-64 T 29-03-2018 MC49_RS16530 a52abd6d2bba12bbef1c238072307a48 224 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 27 181 42.043 T 29-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS06195 e1bccdd0a9dff8e10d2fda1ef5acb7d5 160 Pfam PF13508 Acetyltransferase (GNAT) domain 36 135 1.5E-7 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MC49_RS06195 e1bccdd0a9dff8e10d2fda1ef5acb7d5 160 Gene3D G3DSA:3.40.630.30 11 145 1.0E-13 T 29-03-2018 MC49_RS06195 e1bccdd0a9dff8e10d2fda1ef5acb7d5 160 SUPERFAMILY SSF55729 19 143 1.8E-12 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS01510 f88594d1b0a84774d57b9fa26e64805d 362 Gene3D G3DSA:2.40.10.10 37 133 2.0E-26 T 29-03-2018 MC49_RS01510 f88594d1b0a84774d57b9fa26e64805d 362 SMART SM00228 260 342 6.3E-11 T 29-03-2018 IPR001478 PDZ domain GO:0005515 MC49_RS01510 f88594d1b0a84774d57b9fa26e64805d 362 Pfam PF13365 Trypsin-like peptidase domain 80 218 9.6E-30 T 29-03-2018 MC49_RS01510 f88594d1b0a84774d57b9fa26e64805d 362 Pfam PF13180 PDZ domain 260 350 1.0E-15 T 29-03-2018 IPR001478 PDZ domain GO:0005515 MC49_RS01510 f88594d1b0a84774d57b9fa26e64805d 362 TIGRFAM TIGR02038 protease_degS: periplasmic serine peptidase DegS 4 355 3.2E-135 T 29-03-2018 IPR011783 Peptidase S1C, DegS GO:0004252|GO:0006508 MC49_RS01510 f88594d1b0a84774d57b9fa26e64805d 362 SUPERFAMILY SSF50494 44 257 5.52E-58 T 29-03-2018 IPR009003 Peptidase S1, PA clan MC49_RS01510 f88594d1b0a84774d57b9fa26e64805d 362 Gene3D G3DSA:2.40.10.10 134 247 5.2E-32 T 29-03-2018 MC49_RS01510 f88594d1b0a84774d57b9fa26e64805d 362 SUPERFAMILY SSF50156 244 350 5.52E-22 T 29-03-2018 IPR001478 PDZ domain GO:0005515 MC49_RS01510 f88594d1b0a84774d57b9fa26e64805d 362 Gene3D G3DSA:2.30.42.10 258 359 1.9E-20 T 29-03-2018 MC49_RS01510 f88594d1b0a84774d57b9fa26e64805d 362 PRINTS PR00834 HtrA/DegQ protease family signature 113 133 1.1E-44 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MC49_RS01510 f88594d1b0a84774d57b9fa26e64805d 362 PRINTS PR00834 HtrA/DegQ protease family signature 300 312 1.1E-44 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MC49_RS01510 f88594d1b0a84774d57b9fa26e64805d 362 PRINTS PR00834 HtrA/DegQ protease family signature 154 178 1.1E-44 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MC49_RS01510 f88594d1b0a84774d57b9fa26e64805d 362 PRINTS PR00834 HtrA/DegQ protease family signature 89 101 1.1E-44 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MC49_RS01510 f88594d1b0a84774d57b9fa26e64805d 362 PRINTS PR00834 HtrA/DegQ protease family signature 189 206 1.1E-44 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MC49_RS01510 f88594d1b0a84774d57b9fa26e64805d 362 PRINTS PR00834 HtrA/DegQ protease family signature 211 228 1.1E-44 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MC49_RS16285 2d60aced08c81f41333e18f53c4b8e92 248 SUPERFAMILY SSF48317 22 243 1.44E-48 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MC49_RS16285 2d60aced08c81f41333e18f53c4b8e92 248 PRINTS PR00483 Bacterial acid phosphatase class A signature 66 85 3.0E-57 T 29-03-2018 IPR001011 Acid phosphatase, class A, bacterial GO:0003993|GO:0030288 KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 MC49_RS16285 2d60aced08c81f41333e18f53c4b8e92 248 PRINTS PR00483 Bacterial acid phosphatase class A signature 157 183 3.0E-57 T 29-03-2018 IPR001011 Acid phosphatase, class A, bacterial GO:0003993|GO:0030288 KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 MC49_RS16285 2d60aced08c81f41333e18f53c4b8e92 248 PRINTS PR00483 Bacterial acid phosphatase class A signature 131 149 3.0E-57 T 29-03-2018 IPR001011 Acid phosphatase, class A, bacterial GO:0003993|GO:0030288 KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 MC49_RS16285 2d60aced08c81f41333e18f53c4b8e92 248 PRINTS PR00483 Bacterial acid phosphatase class A signature 189 213 3.0E-57 T 29-03-2018 IPR001011 Acid phosphatase, class A, bacterial GO:0003993|GO:0030288 KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 MC49_RS16285 2d60aced08c81f41333e18f53c4b8e92 248 PRINTS PR00483 Bacterial acid phosphatase class A signature 223 241 3.0E-57 T 29-03-2018 IPR001011 Acid phosphatase, class A, bacterial GO:0003993|GO:0030288 KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 MC49_RS16285 2d60aced08c81f41333e18f53c4b8e92 248 Gene3D G3DSA:1.20.144.10 18 248 4.0E-44 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MC49_RS16285 2d60aced08c81f41333e18f53c4b8e92 248 SMART SM00014 114 226 1.2E-26 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MC49_RS16285 2d60aced08c81f41333e18f53c4b8e92 248 Pfam PF01569 PAP2 superfamily 128 226 6.8E-15 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MC49_RS16285 2d60aced08c81f41333e18f53c4b8e92 248 ProSitePatterns PS01157 Class A bacterial acid phosphatases signature. 161 168 - T 29-03-2018 IPR018296 Acid phosphatase, class A, bacterial, conserved site GO:0003993|GO:0030288 KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 MC49_RS16285 2d60aced08c81f41333e18f53c4b8e92 248 PIRSF PIRSF000897 1 248 3.5E-106 T 29-03-2018 IPR011158 Nonspecific acid phosphatase, class A GO:0003993|GO:0030288 KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 MC49_RS01810 e112535dfa08e2075f5d120b5a4f82b7 308 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 292 1.7E-63 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 MC49_RS01810 e112535dfa08e2075f5d120b5a4f82b7 308 Gene3D G3DSA:1.10.3470.10 4 297 1.0E-51 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like MC49_RS14640 d2399508616ab707088226c3cfe1cc96 106 SUPERFAMILY SSF103481 5 104 5.36E-20 T 29-03-2018 MC49_RS14640 d2399508616ab707088226c3cfe1cc96 106 Pfam PF00893 Small Multidrug Resistance protein 1 92 1.1E-28 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 MC49_RS17110 56d69bd44184463687cbdc7f9be257dc 344 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 344 138.274 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 MC49_RS17110 56d69bd44184463687cbdc7f9be257dc 344 Pfam PF02504 Fatty acid synthesis protein 5 331 2.2E-111 T 29-03-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 MC49_RS17110 56d69bd44184463687cbdc7f9be257dc 344 PIRSF PIRSF002465 2 344 5.2E-124 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 MC49_RS17110 56d69bd44184463687cbdc7f9be257dc 344 SUPERFAMILY SSF53659 4 339 5.35E-103 T 29-03-2018 MC49_RS17110 56d69bd44184463687cbdc7f9be257dc 344 Gene3D G3DSA:3.40.718.10 1 340 7.0E-113 T 29-03-2018 MC49_RS17110 56d69bd44184463687cbdc7f9be257dc 344 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 5 341 1.8E-126 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 MC49_RS15835 e84aa7ad88950700cb5e53a5040a352c 371 Pfam PF01594 AI-2E family transporter 18 345 1.2E-47 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like MC49_RS03275 a10535b5a629608fadb487ea3a47f0dc 155 Gene3D G3DSA:3.20.20.70 10 132 1.8E-11 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS03275 a10535b5a629608fadb487ea3a47f0dc 155 SUPERFAMILY SSF102114 16 129 1.1E-8 T 29-03-2018 MC49_RS03275 a10535b5a629608fadb487ea3a47f0dc 155 TIGRFAM TIGR02491 NrdG: anaerobic ribonucleoside-triphosphate reductase activating protein 2 154 6.1E-61 T 29-03-2018 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 MC49_RS03275 a10535b5a629608fadb487ea3a47f0dc 155 PIRSF PIRSF000368 1 155 6.1E-59 T 29-03-2018 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 MC49_RS03275 a10535b5a629608fadb487ea3a47f0dc 155 ProSitePatterns PS01087 Radical activating enzymes signature. 14 35 - T 29-03-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 MC49_RS03275 a10535b5a629608fadb487ea3a47f0dc 155 Pfam PF13353 4Fe-4S single cluster domain 12 152 1.9E-51 T 29-03-2018 MC49_RS03575 528391d406a0700237113953853730fa 432 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 6 430 3.6E-202 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MC49_RS03575 528391d406a0700237113953853730fa 432 SUPERFAMILY SSF52540 3 431 2.34E-180 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS03575 528391d406a0700237113953853730fa 432 Pfam PF00709 Adenylosuccinate synthetase 5 423 1.9E-179 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MC49_RS03575 528391d406a0700237113953853730fa 432 Gene3D G3DSA:3.90.170.10 267 432 6.6E-67 T 29-03-2018 MC49_RS03575 528391d406a0700237113953853730fa 432 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 11 18 - T 29-03-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MC49_RS03575 528391d406a0700237113953853730fa 432 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 133 144 - T 29-03-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MC49_RS03575 528391d406a0700237113953853730fa 432 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 432 219.353 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MC49_RS03575 528391d406a0700237113953853730fa 432 SMART SM00788 4 425 8.8E-300 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MC49_RS03575 528391d406a0700237113953853730fa 432 Gene3D G3DSA:3.40.440.10 1 150 2.6E-54 T 29-03-2018 MC49_RS03575 528391d406a0700237113953853730fa 432 Gene3D G3DSA:3.40.440.10 151 266 1.7E-26 T 29-03-2018 MC49_RS04350 51048f6796ebfca862b4a7cb81ff5681 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 290 3.1E-30 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS04350 51048f6796ebfca862b4a7cb81ff5681 295 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 28 294 8.8E-86 T 29-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 MC49_RS04350 51048f6796ebfca862b4a7cb81ff5681 295 Gene3D G3DSA:1.10.3720.10 13 287 5.6E-36 T 29-03-2018 MC49_RS04350 51048f6796ebfca862b4a7cb81ff5681 295 SUPERFAMILY SSF161098 38 285 1.26E-33 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS08320 df99d3900e7aa7d6ae0b49f9c46f40b9 216 Pfam PF01810 LysE type translocator 13 210 1.6E-28 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MC49_RS06220 9c59f61080debaf04719fa1d6f8f09f6 331 Hamap MF_01497 Stress response kinase A [srkA]. 7 321 44.762 T 29-03-2018 IPR032882 SrkA/RdoA protein kinase GO:0004674|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 MC49_RS06220 9c59f61080debaf04719fa1d6f8f09f6 331 SUPERFAMILY SSF56112 9 328 6.24E-88 T 29-03-2018 IPR011009 Protein kinase-like domain MC49_RS06220 9c59f61080debaf04719fa1d6f8f09f6 331 Pfam PF01636 Phosphotransferase enzyme family 35 267 1.3E-43 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase MC49_RS06220 9c59f61080debaf04719fa1d6f8f09f6 331 Gene3D G3DSA:3.30.200.20 8 110 1.5E-19 T 29-03-2018 MC49_RS06220 9c59f61080debaf04719fa1d6f8f09f6 331 Gene3D G3DSA:3.90.1200.10 114 322 1.8E-21 T 29-03-2018 MC49_RS10965 e093b4ec296fbacd07804b9e0cf093e7 103 Pfam PF07214 Protein of unknown function (DUF1418) 9 102 5.1E-38 T 29-03-2018 IPR010815 Protein of unknown function DUF1418 MC49_RS05525 08bc5d79d3636d5293715ea461ac12b7 215 Pfam PF00156 Phosphoribosyl transferase domain 49 161 2.1E-11 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MC49_RS05525 08bc5d79d3636d5293715ea461ac12b7 215 SUPERFAMILY SSF53271 2 211 1.7E-46 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like MC49_RS05525 08bc5d79d3636d5293715ea461ac12b7 215 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 215 35.913 T 29-03-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MC49_RS05525 08bc5d79d3636d5293715ea461ac12b7 215 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 10 187 6.3E-68 T 29-03-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MC49_RS05525 08bc5d79d3636d5293715ea461ac12b7 215 Gene3D G3DSA:3.40.50.2020 3 214 2.4E-47 T 29-03-2018 MC49_RS08055 8173ac8dc51e091bf54c5eee6233fef6 257 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 13 241 39.475 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MC49_RS08055 8173ac8dc51e091bf54c5eee6233fef6 257 SUPERFAMILY SSF64005 11 236 3.01E-85 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MC49_RS08055 8173ac8dc51e091bf54c5eee6233fef6 257 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 186 203 - T 29-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 MC49_RS08055 8173ac8dc51e091bf54c5eee6233fef6 257 Pfam PF01255 Putative undecaprenyl diphosphate synthase 20 240 2.2E-80 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MC49_RS08055 8173ac8dc51e091bf54c5eee6233fef6 257 Gene3D G3DSA:3.40.1180.10 1 244 4.1E-90 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MC49_RS08055 8173ac8dc51e091bf54c5eee6233fef6 257 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 14 240 5.3E-95 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MC49_RS01905 81c20f4a798e3dc728b87590af8ceb0c 367 SUPERFAMILY SSF56796 2 362 7.46E-90 T 29-03-2018 MC49_RS01905 81c20f4a798e3dc728b87590af8ceb0c 367 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 351 6.6E-69 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 MC49_RS01905 81c20f4a798e3dc728b87590af8ceb0c 367 Gene3D G3DSA:1.20.1090.10 160 366 1.0E-41 T 29-03-2018 MC49_RS01905 81c20f4a798e3dc728b87590af8ceb0c 367 Gene3D G3DSA:3.40.50.1970 1 159 1.9E-31 T 29-03-2018 MC49_RS01905 81c20f4a798e3dc728b87590af8ceb0c 367 PIRSF PIRSF000112 1 363 1.0E-96 T 29-03-2018 MC49_RS01905 81c20f4a798e3dc728b87590af8ceb0c 367 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 150 178 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 MC49_RS08015 85e5d05327eb6e8d21608c73e8466d00 884 Gene3D G3DSA:1.20.120.330 185 327 9.5E-26 T 29-03-2018 MC49_RS08015 85e5d05327eb6e8d21608c73e8466d00 884 Gene3D G3DSA:3.30.70.260 806 880 6.9E-9 T 29-03-2018 MC49_RS08015 85e5d05327eb6e8d21608c73e8466d00 884 PIRSF PIRSF006288 18 884 0.0 T 29-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 MC49_RS08015 85e5d05327eb6e8d21608c73e8466d00 884 SUPERFAMILY SSF55021 810 874 9.99E-9 T 29-03-2018 MC49_RS08015 85e5d05327eb6e8d21608c73e8466d00 884 SUPERFAMILY SSF81593 202 321 1.65E-9 T 29-03-2018 MC49_RS08015 85e5d05327eb6e8d21608c73e8466d00 884 SUPERFAMILY SSF55021 700 768 4.58E-7 T 29-03-2018 MC49_RS08015 85e5d05327eb6e8d21608c73e8466d00 884 Pfam PF01966 HD domain 462 591 7.1E-14 T 29-03-2018 IPR006674 HD domain MC49_RS08015 85e5d05327eb6e8d21608c73e8466d00 884 Gene3D G3DSA:3.30.460.10 38 180 2.5E-20 T 29-03-2018 MC49_RS08015 85e5d05327eb6e8d21608c73e8466d00 884 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 884 316.276 T 29-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 MC49_RS08015 85e5d05327eb6e8d21608c73e8466d00 884 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 38 877 1.2E-300 T 29-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 MC49_RS08015 85e5d05327eb6e8d21608c73e8466d00 884 SUPERFAMILY SSF109604 428 591 3.77E-13 T 29-03-2018 MC49_RS08015 85e5d05327eb6e8d21608c73e8466d00 884 Pfam PF01909 Nucleotidyltransferase domain 67 115 2.5E-4 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 MC49_RS08015 85e5d05327eb6e8d21608c73e8466d00 884 SUPERFAMILY SSF81301 22 182 1.02E-22 T 29-03-2018 MC49_RS08015 85e5d05327eb6e8d21608c73e8466d00 884 SMART SM00471 457 604 7.8E-9 T 29-03-2018 IPR003607 HD/PDEase domain MC49_RS08015 85e5d05327eb6e8d21608c73e8466d00 884 Gene3D G3DSA:3.30.70.260 691 782 2.4E-7 T 29-03-2018 MC49_RS08015 85e5d05327eb6e8d21608c73e8466d00 884 Pfam PF08335 GlnD PII-uridylyltransferase 185 324 3.5E-37 T 29-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 MC49_RS08015 85e5d05327eb6e8d21608c73e8466d00 884 Gene3D G3DSA:1.10.3090.10 352 662 2.2E-40 T 29-03-2018 MC49_RS08630 8d6e32165e316adc0f2fa7971f9e4142 184 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 95 158 5.0E-17 T 29-03-2018 MC49_RS08630 8d6e32165e316adc0f2fa7971f9e4142 184 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 1 65 2.0E-15 T 29-03-2018 MC49_RS08630 8d6e32165e316adc0f2fa7971f9e4142 184 SUPERFAMILY SSF143414 3 87 2.09E-19 T 29-03-2018 MC49_RS08630 8d6e32165e316adc0f2fa7971f9e4142 184 Pfam PF00936 BMC domain 96 173 3.2E-20 T 29-03-2018 IPR000249 Microcompartment protein, bacteria MC49_RS08630 8d6e32165e316adc0f2fa7971f9e4142 184 Pfam PF00936 BMC domain 4 75 1.6E-17 T 29-03-2018 IPR000249 Microcompartment protein, bacteria MC49_RS08630 8d6e32165e316adc0f2fa7971f9e4142 184 SMART SM00877 95 173 1.5E-22 T 29-03-2018 IPR000249 Microcompartment protein, bacteria MC49_RS08630 8d6e32165e316adc0f2fa7971f9e4142 184 SMART SM00877 3 77 1.3E-15 T 29-03-2018 IPR000249 Microcompartment protein, bacteria MC49_RS08630 8d6e32165e316adc0f2fa7971f9e4142 184 PIRSF PIRSF034834 1 183 1.3E-60 T 29-03-2018 IPR011238 Polyhedral organelle shell protein PduT MC49_RS08630 8d6e32165e316adc0f2fa7971f9e4142 184 SUPERFAMILY SSF143414 95 181 1.57E-22 T 29-03-2018 MC49_RS03735 ac0bc12bba6f7969b115c778e429f699 866 Pfam PF12633 Adenylate cyclase NT domain 5 200 2.6E-77 T 29-03-2018 IPR024685 Adenylate cyclase class-I, N-terminal domain KEGG: 00230+4.6.1.1 MC49_RS03735 ac0bc12bba6f7969b115c778e429f699 866 ProSitePatterns PS01093 Adenylate cyclase class-I signature 2. 605 619 - T 29-03-2018 IPR024686 Adenylate cyclase class-I, conserved site KEGG: 00230+4.6.1.1 MC49_RS03735 ac0bc12bba6f7969b115c778e429f699 866 ProSitePatterns PS01092 Adenylate cyclase class-I signature 1. 242 253 - T 29-03-2018 IPR024686 Adenylate cyclase class-I, conserved site KEGG: 00230+4.6.1.1 MC49_RS03735 ac0bc12bba6f7969b115c778e429f699 866 Pfam PF01295 Adenylate cyclase, class-I 228 831 3.8E-253 T 29-03-2018 IPR000274 Adenylate cyclase, class-I GO:0004016|GO:0006171 KEGG: 00230+4.6.1.1 MC49_RS03735 ac0bc12bba6f7969b115c778e429f699 866 PIRSF PIRSF001444 1 850 0.0 T 29-03-2018 IPR000274 Adenylate cyclase, class-I GO:0004016|GO:0006171 KEGG: 00230+4.6.1.1 MC49_RS01860 5e9622b0e37e4322a7a0aa1d8ca83ad8 630 SUPERFAMILY SSF47364 327 405 9.42E-21 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MC49_RS01860 5e9622b0e37e4322a7a0aa1d8ca83ad8 630 Pfam PF02881 SRP54-type protein, helical bundle domain 344 407 8.1E-11 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MC49_RS01860 5e9622b0e37e4322a7a0aa1d8ca83ad8 630 SMART SM00963 332 412 1.4E-20 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MC49_RS01860 5e9622b0e37e4322a7a0aa1d8ca83ad8 630 Gene3D G3DSA:1.20.120.140 319 414 6.2E-21 T 29-03-2018 MC49_RS01860 5e9622b0e37e4322a7a0aa1d8ca83ad8 630 SMART SM00382 425 576 3.0E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS01860 5e9622b0e37e4322a7a0aa1d8ca83ad8 630 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 355 626 1.3E-114 T 29-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 MC49_RS01860 5e9622b0e37e4322a7a0aa1d8ca83ad8 630 SMART SM00962 426 627 1.8E-124 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MC49_RS01860 5e9622b0e37e4322a7a0aa1d8ca83ad8 630 Pfam PF00448 SRP54-type protein, GTPase domain 427 626 4.3E-78 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MC49_RS01860 5e9622b0e37e4322a7a0aa1d8ca83ad8 630 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 600 613 - T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MC49_RS01860 5e9622b0e37e4322a7a0aa1d8ca83ad8 630 Gene3D G3DSA:3.40.50.300 419 628 4.8E-41 T 29-03-2018 MC49_RS01860 5e9622b0e37e4322a7a0aa1d8ca83ad8 630 SUPERFAMILY SSF52540 424 626 5.58E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS01860 5e9622b0e37e4322a7a0aa1d8ca83ad8 630 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 355 627 64.849 T 29-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 MC49_RS08410 a8c859a10927df7fb1e4f1bcc8586525 262 TIGRFAM TIGR00715 precor6x_red: precorrin-6x reductase 5 246 9.6E-52 T 29-03-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 MC49_RS08410 a8c859a10927df7fb1e4f1bcc8586525 262 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 5 245 3.9E-69 T 29-03-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 MC49_RS08410 a8c859a10927df7fb1e4f1bcc8586525 262 Gene3D G3DSA:3.40.50.2300 67 251 1.4E-8 T 29-03-2018 MC49_RS11330 5d986e78bfed9869871d78b1771e73dc 684 Pfam PF00580 UvrD/REP helicase N-terminal domain 197 486 8.7E-39 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 MC49_RS11330 5d986e78bfed9869871d78b1771e73dc 684 Gene3D G3DSA:3.40.50.300 189 494 2.5E-41 T 29-03-2018 MC49_RS11330 5d986e78bfed9869871d78b1771e73dc 684 SUPERFAMILY SSF52540 195 344 2.56E-83 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS11330 5d986e78bfed9869871d78b1771e73dc 684 SUPERFAMILY SSF52540 385 675 2.56E-83 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS11330 5d986e78bfed9869871d78b1771e73dc 684 Pfam PF13361 UvrD-like helicase C-terminal domain 588 662 1.1E-13 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MC49_RS11330 5d986e78bfed9869871d78b1771e73dc 684 Pfam PF12462 DNA helicase IV / RNA helicase N terminal 1 163 9.1E-61 T 29-03-2018 IPR022161 DNA helicase IV, N-terminal domain MC49_RS11330 5d986e78bfed9869871d78b1771e73dc 684 Gene3D G3DSA:3.40.50.300 495 681 4.6E-25 T 29-03-2018 MC49_RS08815 2ff1dc01da42e1ef9cbfb01c254fd25f 768 Gene3D G3DSA:3.30.365.10 277 434 4.3E-39 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MC49_RS08815 2ff1dc01da42e1ef9cbfb01c254fd25f 768 SUPERFAMILY SSF54665 9 158 1.83E-42 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead MC49_RS08815 2ff1dc01da42e1ef9cbfb01c254fd25f 768 SMART SM01008 24 140 9.5E-45 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead MC49_RS08815 2ff1dc01da42e1ef9cbfb01c254fd25f 768 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 24 140 4.6E-34 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead MC49_RS08815 2ff1dc01da42e1ef9cbfb01c254fd25f 768 Gene3D G3DSA:3.90.1170.50 2 140 2.0E-38 T 29-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead MC49_RS08815 2ff1dc01da42e1ef9cbfb01c254fd25f 768 SUPERFAMILY SSF56003 132 758 5.23E-170 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MC49_RS08815 2ff1dc01da42e1ef9cbfb01c254fd25f 768 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 173 701 3.2E-155 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MC49_RS08815 2ff1dc01da42e1ef9cbfb01c254fd25f 768 Gene3D G3DSA:3.30.365.10 455 613 4.7E-33 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MC49_RS08815 2ff1dc01da42e1ef9cbfb01c254fd25f 768 Gene3D G3DSA:3.30.365.10 169 276 3.6E-24 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MC49_RS08815 2ff1dc01da42e1ef9cbfb01c254fd25f 768 Gene3D G3DSA:3.30.365.10 614 764 7.9E-38 T 29-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MC49_RS10855 d0ad3a23f763a6cd973526c94d9617fd 545 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 8 539 8.5E-116 T 29-03-2018 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 MC49_RS10855 d0ad3a23f763a6cd973526c94d9617fd 545 Pfam PF00999 Sodium/hydrogen exchanger family 7 417 1.5E-63 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 MC49_RS08645 eaec8bed0168225a2f24ddf16a6c3f84 665 SUPERFAMILY SSF56935 42 665 5.13E-86 T 29-03-2018 MC49_RS08645 eaec8bed0168225a2f24ddf16a6c3f84 665 Pfam PF07715 TonB-dependent Receptor Plug Domain 61 167 2.9E-20 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MC49_RS08645 eaec8bed0168225a2f24ddf16a6c3f84 665 Pfam PF00593 TonB dependent receptor 244 662 2.2E-34 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MC49_RS08645 eaec8bed0168225a2f24ddf16a6c3f84 665 Gene3D G3DSA:2.170.130.10 56 179 1.3E-26 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MC49_RS08645 eaec8bed0168225a2f24ddf16a6c3f84 665 Gene3D G3DSA:2.40.170.20 180 665 4.9E-53 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MC49_RS12205 4e1e3c24df3e8e222d850a460bacd1b4 390 Hamap MF_00923 Outer membrane protein assembly factor BamB [bamB]. 2 390 40.02 T 29-03-2018 IPR017687 Outer membrane protein assembly factor BamB MC49_RS12205 4e1e3c24df3e8e222d850a460bacd1b4 390 Gene3D G3DSA:2.140.10.10 27 189 2.9E-29 T 29-03-2018 MC49_RS12205 4e1e3c24df3e8e222d850a460bacd1b4 390 Pfam PF13360 PQQ-like domain 75 317 1.5E-57 T 29-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat MC49_RS12205 4e1e3c24df3e8e222d850a460bacd1b4 390 SUPERFAMILY SSF50998 30 382 5.06E-77 T 29-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MC49_RS12205 4e1e3c24df3e8e222d850a460bacd1b4 390 TIGRFAM TIGR03300 assembly_YfgL: outer membrane assembly lipoprotein YfgL 6 388 4.3E-133 T 29-03-2018 IPR017687 Outer membrane protein assembly factor BamB MC49_RS12205 4e1e3c24df3e8e222d850a460bacd1b4 390 Gene3D G3DSA:2.140.10.10 190 317 1.3E-20 T 29-03-2018 MC49_RS12205 4e1e3c24df3e8e222d850a460bacd1b4 390 SMART SM00564 248 280 0.0066 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MC49_RS12205 4e1e3c24df3e8e222d850a460bacd1b4 390 SMART SM00564 287 318 280.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MC49_RS12205 4e1e3c24df3e8e222d850a460bacd1b4 390 SMART SM00564 198 229 60.0 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MC49_RS12205 4e1e3c24df3e8e222d850a460bacd1b4 390 SMART SM00564 328 359 0.99 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MC49_RS12205 4e1e3c24df3e8e222d850a460bacd1b4 390 SMART SM00564 61 93 0.0051 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MC49_RS12205 4e1e3c24df3e8e222d850a460bacd1b4 390 SMART SM00564 153 184 9.0E-4 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MC49_RS12205 4e1e3c24df3e8e222d850a460bacd1b4 390 SMART SM00564 113 144 6.4E-5 T 29-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MC49_RS12205 4e1e3c24df3e8e222d850a460bacd1b4 390 Gene3D G3DSA:2.130.10.10 318 390 0.17 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MC49_RS03335 80b16a968dfb826643f004e4bee446c3 569 SUPERFAMILY SSF55781 233 355 8.63E-7 T 29-03-2018 IPR029016 GAF domain-like MC49_RS03335 80b16a968dfb826643f004e4bee446c3 569 SMART SM00065 226 365 2.5E-4 T 29-03-2018 IPR003018 GAF domain GO:0005515 MC49_RS03335 80b16a968dfb826643f004e4bee446c3 569 Gene3D G3DSA:3.30.565.10 383 558 7.3E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS03335 80b16a968dfb826643f004e4bee446c3 569 Gene3D G3DSA:3.30.450.40 219 372 1.2E-4 T 29-03-2018 IPR029016 GAF domain-like MC49_RS03335 80b16a968dfb826643f004e4bee446c3 569 SUPERFAMILY SSF55874 426 556 6.85E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS03335 80b16a968dfb826643f004e4bee446c3 569 Pfam PF06580 Histidine kinase 371 447 6.1E-24 T 29-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 MC49_RS03335 80b16a968dfb826643f004e4bee446c3 569 Pfam PF07694 5TMR of 5TMR-LYT 33 196 3.9E-58 T 29-03-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 MC49_RS00460 656d2b0cdc0c4a51b8eadd226b927e2d 240 SUPERFAMILY SSF56300 1 217 5.78E-30 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like MC49_RS00460 656d2b0cdc0c4a51b8eadd226b927e2d 240 Pfam PF00149 Calcineurin-like phosphoesterase 1 199 2.2E-9 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MC49_RS00460 656d2b0cdc0c4a51b8eadd226b927e2d 240 Hamap MF_00575 UDP-2,3-diacylglucosamine hydrolase [lpxH]. 1 240 122.509 T 29-03-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 MC49_RS00460 656d2b0cdc0c4a51b8eadd226b927e2d 240 Gene3D G3DSA:3.60.21.10 1 226 2.4E-23 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like MC49_RS00460 656d2b0cdc0c4a51b8eadd226b927e2d 240 TIGRFAM TIGR01854 lipid_A_lpxH: UDP-2,3-diacylglucosamine diphosphatase 3 231 2.8E-101 T 29-03-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 MC49_RS08545 8fb8f836f2b1fc2de6785b64e368d94a 111 SUPERFAMILY SSF143414 39 108 1.7E-12 T 29-03-2018 MC49_RS08545 8fb8f836f2b1fc2de6785b64e368d94a 111 Pfam PF00936 BMC domain 40 106 2.5E-11 T 29-03-2018 IPR000249 Microcompartment protein, bacteria MC49_RS08545 8fb8f836f2b1fc2de6785b64e368d94a 111 PIRSF PIRSF012296 1 111 1.9E-54 T 29-03-2018 IPR009307 Ethanolamine utilisation EutS GO:0031469 MC49_RS08545 8fb8f836f2b1fc2de6785b64e368d94a 111 SMART SM00877 39 111 2.6E-13 T 29-03-2018 IPR000249 Microcompartment protein, bacteria MC49_RS13575 a36d87b41769bbc5017aa5a3d166538c 530 Gene3D G3DSA:1.20.1250.20 212 405 1.2E-12 T 29-03-2018 MC49_RS13575 a36d87b41769bbc5017aa5a3d166538c 530 SUPERFAMILY SSF103473 13 404 7.46E-53 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS13575 a36d87b41769bbc5017aa5a3d166538c 530 Gene3D G3DSA:1.20.1250.20 2 209 4.5E-25 T 29-03-2018 MC49_RS13575 a36d87b41769bbc5017aa5a3d166538c 530 Pfam PF05977 Transmembrane secretion effector 6 514 2.2E-159 T 29-03-2018 IPR010290 Transmembrane secretion effector MC49_RS01755 18beb50bfe97e58685aaab36c576ed94 227 Gene3D G3DSA:1.10.10.10 122 226 2.3E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS01755 18beb50bfe97e58685aaab36c576ed94 227 SUPERFAMILY SSF52172 3 180 9.51E-36 T 29-03-2018 IPR011006 CheY-like superfamily MC49_RS01755 18beb50bfe97e58685aaab36c576ed94 227 SMART SM00448 2 112 3.7E-36 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS01755 18beb50bfe97e58685aaab36c576ed94 227 SMART SM00862 147 223 6.1E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MC49_RS01755 18beb50bfe97e58685aaab36c576ed94 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 223 5.4E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MC49_RS01755 18beb50bfe97e58685aaab36c576ed94 227 Pfam PF00072 Response regulator receiver domain 4 112 7.8E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS01755 18beb50bfe97e58685aaab36c576ed94 227 Gene3D G3DSA:3.40.50.2300 1 121 1.5E-31 T 29-03-2018 MC49_RS00115 6d3230efd9a42059e368ccf559c9aa3e 130 SUPERFAMILY SSF54001 9 113 5.49E-8 T 29-03-2018 MC49_RS00115 6d3230efd9a42059e368ccf559c9aa3e 130 Gene3D G3DSA:3.90.1720.10 5 128 2.5E-10 T 29-03-2018 MC49_RS00115 6d3230efd9a42059e368ccf559c9aa3e 130 Pfam PF00877 NlpC/P60 family 23 108 1.4E-6 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain MC49_RS10900 37ab31ba3f0ffe97b6404707e18d4c68 437 PIRSF PIRSF000099 1 430 1.3E-163 T 29-03-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MC49_RS10900 37ab31ba3f0ffe97b6404707e18d4c68 437 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 36 426 1.0E-161 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MC49_RS10900 37ab31ba3f0ffe97b6404707e18d4c68 437 SUPERFAMILY SSF53720 8 429 5.3E-87 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MC49_RS10900 37ab31ba3f0ffe97b6404707e18d4c68 437 PRINTS PR00083 Histidinol dehydrogenase signature 137 163 4.1E-98 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MC49_RS10900 37ab31ba3f0ffe97b6404707e18d4c68 437 PRINTS PR00083 Histidinol dehydrogenase signature 198 223 4.1E-98 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MC49_RS10900 37ab31ba3f0ffe97b6404707e18d4c68 437 PRINTS PR00083 Histidinol dehydrogenase signature 230 251 4.1E-98 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MC49_RS10900 37ab31ba3f0ffe97b6404707e18d4c68 437 PRINTS PR00083 Histidinol dehydrogenase signature 252 271 4.1E-98 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MC49_RS10900 37ab31ba3f0ffe97b6404707e18d4c68 437 PRINTS PR00083 Histidinol dehydrogenase signature 168 194 4.1E-98 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MC49_RS10900 37ab31ba3f0ffe97b6404707e18d4c68 437 PRINTS PR00083 Histidinol dehydrogenase signature 320 345 4.1E-98 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MC49_RS10900 37ab31ba3f0ffe97b6404707e18d4c68 437 PRINTS PR00083 Histidinol dehydrogenase signature 361 379 4.1E-98 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MC49_RS10900 37ab31ba3f0ffe97b6404707e18d4c68 437 PRINTS PR00083 Histidinol dehydrogenase signature 36 60 4.1E-98 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MC49_RS10900 37ab31ba3f0ffe97b6404707e18d4c68 437 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 230 262 - T 29-03-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 MC49_RS10900 37ab31ba3f0ffe97b6404707e18d4c68 437 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 7 427 40.684 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MC49_RS10900 37ab31ba3f0ffe97b6404707e18d4c68 437 Pfam PF00815 Histidinol dehydrogenase 29 427 1.9E-165 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MC49_RS10900 37ab31ba3f0ffe97b6404707e18d4c68 437 Gene3D G3DSA:3.40.50.1980 29 225 2.1E-84 T 29-03-2018 MC49_RS10900 37ab31ba3f0ffe97b6404707e18d4c68 437 Gene3D G3DSA:3.40.50.1980 226 371 1.0E-69 T 29-03-2018 MC49_RS09290 6af15c8f3270899f2a658d3dcfb8a3a8 352 SUPERFAMILY SSF56059 110 311 9.72E-23 T 29-03-2018 MC49_RS09290 6af15c8f3270899f2a658d3dcfb8a3a8 352 Gene3D G3DSA:3.30.470.20 109 344 5.7E-27 T 29-03-2018 MC49_RS09290 6af15c8f3270899f2a658d3dcfb8a3a8 352 PIRSF PIRSF029120 1 352 1.1E-127 T 29-03-2018 IPR011226 ATP-grasp family MC49_RS09290 6af15c8f3270899f2a658d3dcfb8a3a8 352 Pfam PF15632 ATP-grasp in the biosynthetic pathway with Ter operon 5 341 2.0E-111 T 29-03-2018 IPR011226 ATP-grasp family MC49_RS01285 81742b799f0d4c8edd8e32d68f05ec47 379 Gene3D G3DSA:3.40.710.10 21 379 1.4E-71 T 29-03-2018 MC49_RS01285 81742b799f0d4c8edd8e32d68f05ec47 379 SUPERFAMILY SSF56601 25 378 2.21E-95 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MC49_RS01285 81742b799f0d4c8edd8e32d68f05ec47 379 ProSitePatterns PS00336 Beta-lactamase class-C active site. 79 86 - T 29-03-2018 IPR001586 Beta-lactamase, class-C active site GO:0008800|GO:0017001|GO:0030288 KEGG: 00311+3.5.2.6 MC49_RS01285 81742b799f0d4c8edd8e32d68f05ec47 379 Pfam PF00144 Beta-lactamase 31 378 4.5E-82 T 29-03-2018 IPR001466 Beta-lactamase-related MC49_RS06970 44826679b0221818fbda18650840abf0 348 SUPERFAMILY SSF51395 26 327 8.96E-74 T 29-03-2018 MC49_RS06970 44826679b0221818fbda18650840abf0 348 Gene3D G3DSA:3.20.20.70 24 264 6.0E-44 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS06970 44826679b0221818fbda18650840abf0 348 Pfam PF01207 Dihydrouridine synthase (Dus) 30 337 2.9E-95 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MC49_RS06970 44826679b0221818fbda18650840abf0 348 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 108 126 - T 29-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 MC49_RS06970 44826679b0221818fbda18650840abf0 348 PIRSF PIRSF006621 16 348 3.1E-71 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MC49_RS06970 44826679b0221818fbda18650840abf0 348 Hamap MF_02041 tRNA-dihydrouridine(20/20a) synthase [dusA]. 21 343 52.372 T 29-03-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 MC49_RS06970 44826679b0221818fbda18650840abf0 348 TIGRFAM TIGR00742 yjbN: tRNA dihydrouridine synthase A 26 342 5.1E-164 T 29-03-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 MC49_RS14195 1d2647c1feac11c6d2b4b1d255a28109 316 Pfam PF04198 Putative sugar-binding domain 64 312 1.9E-65 T 29-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 MC49_RS14195 1d2647c1feac11c6d2b4b1d255a28109 316 Pfam PF00325 Bacterial regulatory proteins, crp family 28 57 1.3E-4 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MC49_RS14195 1d2647c1feac11c6d2b4b1d255a28109 316 Gene3D G3DSA:1.10.10.10 2 60 2.7E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS14195 1d2647c1feac11c6d2b4b1d255a28109 316 SUPERFAMILY SSF100950 64 314 2.6E-57 T 29-03-2018 MC49_RS14195 1d2647c1feac11c6d2b4b1d255a28109 316 Gene3D G3DSA:3.40.50.1360 66 314 2.0E-33 T 29-03-2018 MC49_RS11500 19e3d266a5b31cad9615ffdb73438d11 507 SMART SM00283 255 502 4.0E-82 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MC49_RS11500 19e3d266a5b31cad9615ffdb73438d11 507 SMART SM00304 200 254 2.7E-4 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MC49_RS11500 19e3d266a5b31cad9615ffdb73438d11 507 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 313 470 9.5E-49 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 MC49_RS11500 19e3d266a5b31cad9615ffdb73438d11 507 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 162 187 1.2E-6 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS11500 19e3d266a5b31cad9615ffdb73438d11 507 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 430 459 1.2E-6 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 MC49_RS11500 19e3d266a5b31cad9615ffdb73438d11 507 Gene3D G3DSA:1.20.120.30 31 148 9.8E-13 T 29-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain MC49_RS11500 19e3d266a5b31cad9615ffdb73438d11 507 SUPERFAMILY SSF58104 228 503 2.88E-65 T 29-03-2018 MC49_RS11500 19e3d266a5b31cad9615ffdb73438d11 507 Gene3D G3DSA:1.10.287.950 306 506 1.8E-41 T 29-03-2018 MC49_RS11500 19e3d266a5b31cad9615ffdb73438d11 507 Gene3D G3DSA:1.10.287.950 149 305 2.1E-14 T 29-03-2018 MC49_RS14505 92723b4529b906de8e471fb199a13fbb 456 Gene3D G3DSA:3.40.250.10 290 445 8.4E-20 T 29-03-2018 IPR001763 Rhodanese-like domain MC49_RS14505 92723b4529b906de8e471fb199a13fbb 456 Gene3D G3DSA:3.40.250.10 141 285 4.5E-20 T 29-03-2018 IPR001763 Rhodanese-like domain MC49_RS14505 92723b4529b906de8e471fb199a13fbb 456 SUPERFAMILY SSF52821 296 434 9.95E-30 T 29-03-2018 IPR001763 Rhodanese-like domain MC49_RS14505 92723b4529b906de8e471fb199a13fbb 456 Gene3D G3DSA:3.40.250.10 20 132 9.4E-14 T 29-03-2018 IPR001763 Rhodanese-like domain MC49_RS14505 92723b4529b906de8e471fb199a13fbb 456 SUPERFAMILY SSF52821 21 142 4.45E-15 T 29-03-2018 IPR001763 Rhodanese-like domain MC49_RS14505 92723b4529b906de8e471fb199a13fbb 456 SUPERFAMILY SSF52821 141 283 5.63E-25 T 29-03-2018 IPR001763 Rhodanese-like domain MC49_RS14505 92723b4529b906de8e471fb199a13fbb 456 Pfam PF00581 Rhodanese-like domain 173 268 6.2E-12 T 29-03-2018 IPR001763 Rhodanese-like domain MC49_RS14505 92723b4529b906de8e471fb199a13fbb 456 Pfam PF00581 Rhodanese-like domain 28 121 1.4E-8 T 29-03-2018 IPR001763 Rhodanese-like domain MC49_RS14505 92723b4529b906de8e471fb199a13fbb 456 Pfam PF00581 Rhodanese-like domain 307 422 1.8E-10 T 29-03-2018 IPR001763 Rhodanese-like domain MC49_RS14505 92723b4529b906de8e471fb199a13fbb 456 SMART SM00450 25 137 4.3E-4 T 29-03-2018 IPR001763 Rhodanese-like domain MC49_RS14505 92723b4529b906de8e471fb199a13fbb 456 SMART SM00450 148 272 2.2E-13 T 29-03-2018 IPR001763 Rhodanese-like domain MC49_RS14505 92723b4529b906de8e471fb199a13fbb 456 SMART SM00450 298 426 1.5E-4 T 29-03-2018 IPR001763 Rhodanese-like domain MC49_RS15840 b489e5b03098b3b8a95a46c3706d9a95 792 PIRSF PIRSF000854 6 792 0.0 T 29-03-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 MC49_RS15840 b489e5b03098b3b8a95a46c3706d9a95 792 Gene3D G3DSA:3.50.30.10 361 480 6.2E-37 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MC49_RS15840 b489e5b03098b3b8a95a46c3706d9a95 792 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 417 428 - T 29-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 MC49_RS15840 b489e5b03098b3b8a95a46c3706d9a95 792 Gene3D G3DSA:3.20.20.60 481 792 2.7E-103 T 29-03-2018 MC49_RS15840 b489e5b03098b3b8a95a46c3706d9a95 792 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 23 349 1.5E-119 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 MC49_RS15840 b489e5b03098b3b8a95a46c3706d9a95 792 SUPERFAMILY SSF51621 467 790 8.11E-95 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MC49_RS15840 b489e5b03098b3b8a95a46c3706d9a95 792 SUPERFAMILY SSF52009 351 469 9.29E-36 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MC49_RS15840 b489e5b03098b3b8a95a46c3706d9a95 792 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 11 790 0.0 T 29-03-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 MC49_RS15840 b489e5b03098b3b8a95a46c3706d9a95 792 Pfam PF00391 PEP-utilising enzyme, mobile domain 387 458 1.1E-27 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MC49_RS15840 b489e5b03098b3b8a95a46c3706d9a95 792 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 697 715 - T 29-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 MC49_RS15840 b489e5b03098b3b8a95a46c3706d9a95 792 Gene3D G3DSA:3.30.1490.20 7 198 9.8E-53 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MC49_RS15840 b489e5b03098b3b8a95a46c3706d9a95 792 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 485 789 2.4E-59 T 29-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 MC49_RS15840 b489e5b03098b3b8a95a46c3706d9a95 792 SUPERFAMILY SSF56059 10 388 1.06E-107 T 29-03-2018 MC49_RS15840 b489e5b03098b3b8a95a46c3706d9a95 792 Gene3D G3DSA:3.30.470.20 199 360 5.2E-46 T 29-03-2018 MC49_RS00955 c0e3b831d84cc0ebd61e01d6343f1913 209 SUPERFAMILY SSF46689 20 85 9.22E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS00955 c0e3b831d84cc0ebd61e01d6343f1913 209 Gene3D G3DSA:1.10.10.60 2 52 2.6E-11 T 29-03-2018 MC49_RS00955 c0e3b831d84cc0ebd61e01d6343f1913 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 4.9E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS00955 c0e3b831d84cc0ebd61e01d6343f1913 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 4.9E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS00955 c0e3b831d84cc0ebd61e01d6343f1913 209 Gene3D G3DSA:1.10.260.40 53 73 0.0014 T 29-03-2018 MC49_RS00955 c0e3b831d84cc0ebd61e01d6343f1913 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 73 5.0E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS00955 c0e3b831d84cc0ebd61e01d6343f1913 209 Gene3D G3DSA:1.10.357.10 74 209 3.5E-8 T 29-03-2018 MC49_RS07360 dc2f51af980343616439658d8fc9bea7 180 SUPERFAMILY SSF88946 15 91 4.71E-12 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS07360 dc2f51af980343616439658d8fc9bea7 180 Gene3D G3DSA:1.10.1740.10 5 78 3.0E-12 T 29-03-2018 MC49_RS07360 dc2f51af980343616439658d8fc9bea7 180 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 14 171 1.5E-28 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS07360 dc2f51af980343616439658d8fc9bea7 180 Gene3D G3DSA:1.10.10.10 79 174 9.6E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS07360 dc2f51af980343616439658d8fc9bea7 180 Pfam PF04542 Sigma-70 region 2 15 80 8.3E-11 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS07360 dc2f51af980343616439658d8fc9bea7 180 SUPERFAMILY SSF88659 97 172 4.86E-18 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS07360 dc2f51af980343616439658d8fc9bea7 180 Pfam PF08281 Sigma-70, region 4 115 167 2.2E-19 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS03310 6749a39492ac193d9a7c25d5252b681c 292 Pfam PF01136 Peptidase family U32 83 210 1.5E-12 T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 MC49_RS01045 39e4b82818e1a8f9690979b0636070d7 234 Pfam PF04335 VirB8 protein 23 225 5.1E-71 T 29-03-2018 IPR007430 Bacterial virulence protein VirB8 GO:0016020 MC49_RS01045 39e4b82818e1a8f9690979b0636070d7 234 SUPERFAMILY SSF54427 94 226 4.07E-28 T 29-03-2018 IPR032710 NTF2-like domain MC49_RS08635 63562c21b0305116f14ff922f3320c91 354 SMART SM00342 263 349 1.5E-23 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MC49_RS08635 63562c21b0305116f14ff922f3320c91 354 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 300 345 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MC49_RS08635 63562c21b0305116f14ff922f3320c91 354 Pfam PF12833 Helix-turn-helix domain 269 351 3.0E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MC49_RS08635 63562c21b0305116f14ff922f3320c91 354 SUPERFAMILY SSF46689 247 297 1.08E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS08635 63562c21b0305116f14ff922f3320c91 354 Gene3D G3DSA:1.10.10.60 169 298 2.2E-11 T 29-03-2018 MC49_RS08635 63562c21b0305116f14ff922f3320c91 354 Gene3D G3DSA:1.10.10.60 299 354 5.1E-7 T 29-03-2018 MC49_RS04415 aec90e97736b8781db0ef6e6ccd5123e 108 SUPERFAMILY SSF52821 2 104 1.57E-28 T 29-03-2018 IPR001763 Rhodanese-like domain MC49_RS04415 aec90e97736b8781db0ef6e6ccd5123e 108 Gene3D G3DSA:3.40.250.10 1 108 8.4E-27 T 29-03-2018 IPR001763 Rhodanese-like domain MC49_RS04415 aec90e97736b8781db0ef6e6ccd5123e 108 Pfam PF00581 Rhodanese-like domain 11 98 9.6E-14 T 29-03-2018 IPR001763 Rhodanese-like domain MC49_RS04415 aec90e97736b8781db0ef6e6ccd5123e 108 Hamap MF_01009 Thiosulfate sulfurtransferase GlpE [glpE]. 2 105 31.339 T 29-03-2018 IPR023695 Thiosulfate sulfurtransferase, bacterial GO:0004792|GO:0005737 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 MC49_RS04415 aec90e97736b8781db0ef6e6ccd5123e 108 SMART SM00450 7 102 8.6E-20 T 29-03-2018 IPR001763 Rhodanese-like domain MC49_RS13430 da42bd1666d000c8cd2c306a1d4b4b66 358 SUPERFAMILY SSF53756 16 346 2.36E-42 T 29-03-2018 MC49_RS13430 da42bd1666d000c8cd2c306a1d4b4b66 358 Pfam PF00534 Glycosyl transferases group 1 174 329 5.0E-22 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 MC49_RS13430 da42bd1666d000c8cd2c306a1d4b4b66 358 Gene3D G3DSA:3.40.50.2000 171 347 7.1E-25 T 29-03-2018 MC49_RS13430 da42bd1666d000c8cd2c306a1d4b4b66 358 Pfam PF13439 Glycosyltransferase Family 4 17 172 2.0E-8 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 MC49_RS10940 0938ae47d2a721168b8cf74eda4567e7 439 Pfam PF03222 Tryptophan/tyrosine permease family 34 401 1.2E-11 T 29-03-2018 IPR018227 Amino acid/polyamine transporter 2 GO:0003333 MC49_RS10940 0938ae47d2a721168b8cf74eda4567e7 439 TIGRFAM TIGR00814 stp: serine transporter 22 424 4.5E-176 T 29-03-2018 IPR004694 Hydroxy amino acid transporter GO:0005215|GO:0006810|GO:0016021 MC49_RS02565 42ce3296c04a1f4455b141a3b68d371b 378 Gene3D G3DSA:3.90.1150.10 273 368 1.2E-4 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS02565 42ce3296c04a1f4455b141a3b68d371b 378 Hamap MF_00609 Histidine decarboxylase [hdc]. 2 374 71.616 T 29-03-2018 IPR023523 Histidine decarboxylase, bacteria GO:0004398|GO:0030170 KEGG: 00340+4.1.1.22|MetaCyc: PWY-6173 MC49_RS02565 42ce3296c04a1f4455b141a3b68d371b 378 SUPERFAMILY SSF53383 21 370 3.87E-79 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS02565 42ce3296c04a1f4455b141a3b68d371b 378 Gene3D G3DSA:3.40.640.10 56 272 7.4E-33 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS02565 42ce3296c04a1f4455b141a3b68d371b 378 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 112 314 4.8E-26 T 29-03-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 MC49_RS02565 42ce3296c04a1f4455b141a3b68d371b 378 ProSitePatterns PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. 226 247 - T 29-03-2018 IPR021115 Pyridoxal-phosphate binding site GO:0016831 MC49_RS10905 b4e9e7d7fa95bb7e905c5d652dabd239 299 Pfam PF08029 HisG, C-terminal domain 223 296 3.0E-23 T 29-03-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 MC49_RS10905 b4e9e7d7fa95bb7e905c5d652dabd239 299 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 156 177 - T 29-03-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 MC49_RS10905 b4e9e7d7fa95bb7e905c5d652dabd239 299 SUPERFAMILY SSF53850 6 224 1.97E-69 T 29-03-2018 MC49_RS10905 b4e9e7d7fa95bb7e905c5d652dabd239 299 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 205 298 1.1E-30 T 29-03-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 MC49_RS10905 b4e9e7d7fa95bb7e905c5d652dabd239 299 Gene3D G3DSA:3.30.70.120 227 298 1.4E-23 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MC49_RS10905 b4e9e7d7fa95bb7e905c5d652dabd239 299 Gene3D G3DSA:3.40.190.10 129 223 1.6E-21 T 29-03-2018 MC49_RS10905 b4e9e7d7fa95bb7e905c5d652dabd239 299 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 6 299 35.297 T 29-03-2018 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 MC49_RS10905 b4e9e7d7fa95bb7e905c5d652dabd239 299 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 7 197 2.3E-57 T 29-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 MC49_RS10905 b4e9e7d7fa95bb7e905c5d652dabd239 299 Gene3D G3DSA:3.40.190.10 1 128 5.0E-35 T 29-03-2018 MC49_RS10905 b4e9e7d7fa95bb7e905c5d652dabd239 299 Pfam PF01634 ATP phosphoribosyltransferase 54 219 5.6E-47 T 29-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 MC49_RS10905 b4e9e7d7fa95bb7e905c5d652dabd239 299 SUPERFAMILY SSF54913 226 298 9.45E-21 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta MC49_RS02750 b65ebb9d29d0e65c52af6b487378ecf0 686 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 68 87 4.1E-56 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MC49_RS02750 b65ebb9d29d0e65c52af6b487378ecf0 686 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 149 167 4.1E-56 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MC49_RS02750 b65ebb9d29d0e65c52af6b487378ecf0 686 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 230 244 4.1E-56 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MC49_RS02750 b65ebb9d29d0e65c52af6b487378ecf0 686 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 31 44 4.1E-56 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MC49_RS02750 b65ebb9d29d0e65c52af6b487378ecf0 686 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 179 196 4.1E-56 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MC49_RS02750 b65ebb9d29d0e65c52af6b487378ecf0 686 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 130 146 4.1E-56 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MC49_RS02750 b65ebb9d29d0e65c52af6b487378ecf0 686 PIRSF PIRSF005419 1 686 1.6E-212 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MC49_RS02750 b65ebb9d29d0e65c52af6b487378ecf0 686 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 135 158 - T 29-03-2018 IPR025505 FHIPEP conserved site MC49_RS02750 b65ebb9d29d0e65c52af6b487378ecf0 686 TIGRFAM TIGR01399 hrcV: type III secretion protein, HrcV family 12 686 1.8E-240 T 29-03-2018 IPR006302 Type III secretion protein HrcV GO:0015031|GO:0016021 MC49_RS02750 b65ebb9d29d0e65c52af6b487378ecf0 686 Pfam PF00771 FHIPEP family 24 678 1.3E-214 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MC49_RS04700 530bf30890dab068feb275bc7a2b9b4f 360 Pfam PF01761 3-dehydroquinate synthase 67 326 3.0E-109 T 29-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 MC49_RS04700 530bf30890dab068feb275bc7a2b9b4f 360 SUPERFAMILY SSF56796 4 358 5.5E-118 T 29-03-2018 MC49_RS04700 530bf30890dab068feb275bc7a2b9b4f 360 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 14 356 2.1E-121 T 29-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 MC49_RS04700 530bf30890dab068feb275bc7a2b9b4f 360 PIRSF PIRSF001455 12 359 7.7E-106 T 29-03-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 MC49_RS04700 530bf30890dab068feb275bc7a2b9b4f 360 Gene3D G3DSA:1.20.1090.10 173 360 4.3E-66 T 29-03-2018 MC49_RS04700 530bf30890dab068feb275bc7a2b9b4f 360 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 2 359 43.281 T 29-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 MC49_RS04700 530bf30890dab068feb275bc7a2b9b4f 360 Gene3D G3DSA:3.40.50.1970 2 172 8.9E-52 T 29-03-2018 MC49_RS10800 8169801ca16dd95919f6678e4c6ebb86 370 Hamap MF_02040 Iron-sulfur cluster carrier protein. 102 351 37.027 T 29-03-2018 IPR019591 Mrp/NBP35 ATP-binding protein MC49_RS10800 8169801ca16dd95919f6678e4c6ebb86 370 Gene3D G3DSA:3.40.50.300 98 329 7.2E-61 T 29-03-2018 MC49_RS10800 8169801ca16dd95919f6678e4c6ebb86 370 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 107 350 7.5E-100 T 29-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 MC49_RS10800 8169801ca16dd95919f6678e4c6ebb86 370 SUPERFAMILY SSF52540 100 335 4.28E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS10800 8169801ca16dd95919f6678e4c6ebb86 370 ProSitePatterns PS01215 Mrp family signature. 214 230 - T 29-03-2018 IPR000808 Mrp, conserved site GO:0005524 MC49_RS14350 774359e1e35be14e6d006ceda344643b 112 PIRSF PIRSF025560 2 111 4.7E-36 T 29-03-2018 IPR008309 Uncharacterised conserved protein UCP025560 MC49_RS14350 774359e1e35be14e6d006ceda344643b 112 Pfam PF07027 Protein of unknown function (DUF1318) 19 111 6.4E-30 T 29-03-2018 IPR008309 Uncharacterised conserved protein UCP025560 MC49_RS05585 ae1c6d153153a70b67f17fb64ecc1f4d 259 Gene3D G3DSA:3.90.550.10 1 243 1.3E-22 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MC49_RS05585 ae1c6d153153a70b67f17fb64ecc1f4d 259 Pfam PF00535 Glycosyl transferase family 2 8 132 6.2E-16 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MC49_RS05585 ae1c6d153153a70b67f17fb64ecc1f4d 259 SUPERFAMILY SSF53448 2 144 1.31E-24 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MC49_RS11410 c580ed26a236b4e63b3226de4b6c338e 113 Pfam PF08956 Domain of unknown function (DUF1869) 55 113 1.5E-33 T 29-03-2018 IPR015051 Protein YoaG MC49_RS11410 c580ed26a236b4e63b3226de4b6c338e 113 SUPERFAMILY SSF103063 4 48 5.62E-5 T 29-03-2018 IPR015051 Protein YoaG MC49_RS11410 c580ed26a236b4e63b3226de4b6c338e 113 Gene3D G3DSA:3.30.160.220 5 56 3.5E-17 T 29-03-2018 IPR015051 Protein YoaG MC49_RS11410 c580ed26a236b4e63b3226de4b6c338e 113 Gene3D G3DSA:3.30.160.220 57 108 1.9E-21 T 29-03-2018 IPR015051 Protein YoaG MC49_RS11410 c580ed26a236b4e63b3226de4b6c338e 113 SUPERFAMILY SSF103063 55 113 5.89E-21 T 29-03-2018 IPR015051 Protein YoaG MC49_RS10960 98d2f63c1e5ff8434f65e0d740b333db 87 SUPERFAMILY SSF52833 4 81 1.8E-21 T 29-03-2018 IPR012336 Thioredoxin-like fold MC49_RS10960 98d2f63c1e5ff8434f65e0d740b333db 87 Gene3D G3DSA:3.40.30.10 1 83 6.8E-21 T 29-03-2018 MC49_RS10960 98d2f63c1e5ff8434f65e0d740b333db 87 TIGRFAM TIGR02183 GRXA: glutaredoxin, GrxA family 2 86 1.2E-50 T 29-03-2018 IPR011902 Glutaredoxin, GrxA GO:0009055|GO:0015035|GO:0045454 MC49_RS10960 98d2f63c1e5ff8434f65e0d740b333db 87 Pfam PF00462 Glutaredoxin 4 69 1.4E-16 T 29-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 MC49_RS10960 98d2f63c1e5ff8434f65e0d740b333db 87 PRINTS PR00160 Glutaredoxin signature 66 79 3.1E-12 T 29-03-2018 IPR014025 Glutaredoxin subgroup MC49_RS10960 98d2f63c1e5ff8434f65e0d740b333db 87 PRINTS PR00160 Glutaredoxin signature 52 65 3.1E-12 T 29-03-2018 IPR014025 Glutaredoxin subgroup MC49_RS10960 98d2f63c1e5ff8434f65e0d740b333db 87 PRINTS PR00160 Glutaredoxin signature 3 21 3.1E-12 T 29-03-2018 IPR014025 Glutaredoxin subgroup MC49_RS10960 98d2f63c1e5ff8434f65e0d740b333db 87 ProSitePatterns PS00195 Glutaredoxin active site. 5 20 - T 29-03-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 MC49_RS18015 08540a37fdf864a9a099e69e8a64f551 318 TIGRFAM TIGR01139 cysK: cysteine synthase A 9 312 3.3E-143 T 29-03-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 MC49_RS18015 08540a37fdf864a9a099e69e8a64f551 318 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 31 49 - T 29-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 MC49_RS18015 08540a37fdf864a9a099e69e8a64f551 318 Gene3D G3DSA:3.40.50.1100 40 137 5.2E-33 T 29-03-2018 MC49_RS18015 08540a37fdf864a9a099e69e8a64f551 318 SUPERFAMILY SSF53686 3 314 1.31E-100 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MC49_RS18015 08540a37fdf864a9a099e69e8a64f551 318 Gene3D G3DSA:3.40.50.1100 138 318 4.1E-61 T 29-03-2018 MC49_RS18015 08540a37fdf864a9a099e69e8a64f551 318 TIGRFAM TIGR01136 cysKM: cysteine synthase 10 312 3.3E-135 T 29-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 MC49_RS18015 08540a37fdf864a9a099e69e8a64f551 318 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 300 1.4E-71 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MC49_RS14530 b50ec2cc4492a050077932b5beccbfb4 248 Gene3D G3DSA:3.40.50.300 1 228 1.4E-42 T 29-03-2018 MC49_RS14530 b50ec2cc4492a050077932b5beccbfb4 248 SUPERFAMILY SSF52540 2 218 6.12E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS14530 b50ec2cc4492a050077932b5beccbfb4 248 Pfam PF00005 ABC transporter 21 156 8.2E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS14530 b50ec2cc4492a050077932b5beccbfb4 248 SMART SM00382 26 205 1.3E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS07825 17a590cacfa489b6815f3b85192c8da8 791 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 499 511 1.9E-8 T 29-03-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS07825 17a590cacfa489b6815f3b85192c8da8 791 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 551 559 1.9E-8 T 29-03-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS07825 17a590cacfa489b6815f3b85192c8da8 791 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 427 440 1.9E-8 T 29-03-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS07825 17a590cacfa489b6815f3b85192c8da8 791 Gene3D G3DSA:3.90.1600.10 401 611 4.2E-47 T 29-03-2018 IPR023211 DNA polymerase, palm domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS07825 17a590cacfa489b6815f3b85192c8da8 791 Pfam PF00136 DNA polymerase family B 500 742 2.0E-23 T 29-03-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS07825 17a590cacfa489b6815f3b85192c8da8 791 Pfam PF00136 DNA polymerase family B 390 443 9.8E-9 T 29-03-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS07825 17a590cacfa489b6815f3b85192c8da8 791 SMART SM00486 159 565 7.1E-66 T 29-03-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS07825 17a590cacfa489b6815f3b85192c8da8 791 SUPERFAMILY SSF53098 18 401 1.81E-84 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MC49_RS07825 17a590cacfa489b6815f3b85192c8da8 791 Gene3D G3DSA:3.30.420.10 162 359 3.2E-37 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MC49_RS07825 17a590cacfa489b6815f3b85192c8da8 791 ProSitePatterns PS00116 DNA polymerase family B signature. 553 561 - T 29-03-2018 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS07825 17a590cacfa489b6815f3b85192c8da8 791 SUPERFAMILY SSF56672 396 786 1.11E-108 T 29-03-2018 MC49_RS04650 db71942198b62f538ca7e41b15020709 203 Pfam PF02613 Nitrate reductase delta subunit 57 158 1.1E-23 T 29-03-2018 IPR020945 DMSO/Nitrate reductase chaperone MC49_RS04650 db71942198b62f538ca7e41b15020709 203 Gene3D G3DSA:1.10.3480.10 2 203 1.6E-48 T 29-03-2018 IPR020945 DMSO/Nitrate reductase chaperone MC49_RS04650 db71942198b62f538ca7e41b15020709 203 SUPERFAMILY SSF89155 9 198 4.06E-46 T 29-03-2018 IPR020945 DMSO/Nitrate reductase chaperone MC49_RS04650 db71942198b62f538ca7e41b15020709 203 PIRSF PIRSF004690 1 198 2.4E-60 T 29-03-2018 IPR026269 Tat proofreading chaperone DmsD-type MC49_RS04650 db71942198b62f538ca7e41b15020709 203 Hamap MF_00940 Tat proofreading chaperone DmsD [dmsD]. 4 203 41.568 T 29-03-2018 IPR028611 Tat proofreading chaperone DmsD GO:0005048 MC49_RS02735 779d5836bc8e47e70f24fd918e8b7b45 132 Gene3D G3DSA:1.20.5.50 2 132 2.5E-4 T 29-03-2018 MC49_RS09310 bced018ed81781d0325be4fb0dba89ee 344 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 10 337 6.6E-105 T 29-03-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 MC49_RS09310 bced018ed81781d0325be4fb0dba89ee 344 Pfam PF03741 Integral membrane protein TerC family 73 299 3.3E-43 T 29-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 MC49_RS16690 117cca7ce1e535b2ca2d9534dbeea9c6 175 Gene3D G3DSA:3.40.630.30 1 89 3.7E-13 T 29-03-2018 MC49_RS16690 117cca7ce1e535b2ca2d9534dbeea9c6 175 Pfam PF13673 Acetyltransferase (GNAT) domain 46 144 1.0E-13 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MC49_RS16690 117cca7ce1e535b2ca2d9534dbeea9c6 175 SUPERFAMILY SSF55729 9 146 1.28E-24 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS16690 117cca7ce1e535b2ca2d9534dbeea9c6 175 Gene3D G3DSA:3.40.630.30 90 161 1.7E-14 T 29-03-2018 MC49_RS10110 83c76e12249ba8bfd9b63871d6a1ce76 626 Pfam PF03717 Penicillin-binding Protein dimerisation domain 60 235 1.1E-46 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 MC49_RS10110 83c76e12249ba8bfd9b63871d6a1ce76 626 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 15 605 1.9E-229 T 29-03-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0016020 MC49_RS10110 83c76e12249ba8bfd9b63871d6a1ce76 626 SUPERFAMILY SSF56601 250 605 2.91E-89 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MC49_RS10110 83c76e12249ba8bfd9b63871d6a1ce76 626 Gene3D G3DSA:3.90.1310.10 29 245 4.1E-53 T 29-03-2018 MC49_RS10110 83c76e12249ba8bfd9b63871d6a1ce76 626 SUPERFAMILY SSF56519 52 249 1.16E-51 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 MC49_RS10110 83c76e12249ba8bfd9b63871d6a1ce76 626 Gene3D G3DSA:3.40.710.10 246 611 5.1E-79 T 29-03-2018 MC49_RS10110 83c76e12249ba8bfd9b63871d6a1ce76 626 Pfam PF00905 Penicillin binding protein transpeptidase domain 268 602 3.5E-78 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MC49_RS06910 55936cf0d5aeabee1e9024c20a8fdf37 260 SUPERFAMILY SSF54616 17 106 8.76E-7 T 29-03-2018 IPR003163 Transcription regulator HTH, APSES-type DNA-binding domain GO:0003677 MC49_RS06910 55936cf0d5aeabee1e9024c20a8fdf37 260 Pfam PF04383 KilA-N domain 9 110 1.7E-18 T 29-03-2018 IPR018004 KilA, N-terminal/APSES-type HTH, DNA-binding MC49_RS06910 55936cf0d5aeabee1e9024c20a8fdf37 260 SMART SM01252 10 113 1.6E-19 T 29-03-2018 IPR018004 KilA, N-terminal/APSES-type HTH, DNA-binding MC49_RS06910 55936cf0d5aeabee1e9024c20a8fdf37 260 Pfam PF10546 P63C domain 130 204 5.1E-9 T 29-03-2018 IPR018874 Bacteriophage Mx8, p63, C-terminal MC49_RS13515 e924b49f8f63595b252a4d9c2435b753 455 Gene3D G3DSA:1.10.287.130 211 280 3.4E-10 T 29-03-2018 MC49_RS13515 e924b49f8f63595b252a4d9c2435b753 455 SMART SM00388 221 286 4.6E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS13515 e924b49f8f63595b252a4d9c2435b753 455 SUPERFAMILY SSF47384 205 286 2.94E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS13515 e924b49f8f63595b252a4d9c2435b753 455 SMART SM00387 331 442 1.6E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS13515 e924b49f8f63595b252a4d9c2435b753 455 Pfam PF00512 His Kinase A (phospho-acceptor) domain 223 285 3.0E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS13515 e924b49f8f63595b252a4d9c2435b753 455 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 332 440 2.0E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS13515 e924b49f8f63595b252a4d9c2435b753 455 SUPERFAMILY SSF55874 276 440 3.67E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS13515 e924b49f8f63595b252a4d9c2435b753 455 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 439 4.1E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS13515 e924b49f8f63595b252a4d9c2435b753 455 PRINTS PR00344 Bacterial sensor protein C-terminal signature 369 383 4.1E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS13515 e924b49f8f63595b252a4d9c2435b753 455 PRINTS PR00344 Bacterial sensor protein C-terminal signature 387 397 4.1E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS13515 e924b49f8f63595b252a4d9c2435b753 455 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 419 4.1E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS13515 e924b49f8f63595b252a4d9c2435b753 455 Gene3D G3DSA:3.30.565.10 281 442 5.7E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS01805 4fdca9e0f2ad44462950050117a73d2d 427 Pfam PF11862 Domain of unknown function (DUF3382) 5 103 2.3E-23 T 29-03-2018 IPR021807 High-affinity branched-chain amino acid transport system permease, LivHM, N-terminal MC49_RS01805 4fdca9e0f2ad44462950050117a73d2d 427 Gene3D G3DSA:1.10.3470.10 3 402 4.7E-44 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like MC49_RS01805 4fdca9e0f2ad44462950050117a73d2d 427 Pfam PF02653 Branched-chain amino acid transport system / permease component 113 398 1.1E-55 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 MC49_RS12805 b0c96722a46018d05b4e03ddb1479769 401 ProSitePatterns PS00594 Aromatic amino acids permeases signature. 17 33 - T 29-03-2018 IPR013061 Tryptophan/tryrosine permease, conserved site MC49_RS12805 b0c96722a46018d05b4e03ddb1479769 401 PRINTS PR00166 Aromatic amino acid permease signature 82 102 9.5E-76 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS12805 b0c96722a46018d05b4e03ddb1479769 401 PRINTS PR00166 Aromatic amino acid permease signature 182 204 9.5E-76 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS12805 b0c96722a46018d05b4e03ddb1479769 401 PRINTS PR00166 Aromatic amino acid permease signature 282 301 9.5E-76 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS12805 b0c96722a46018d05b4e03ddb1479769 401 PRINTS PR00166 Aromatic amino acid permease signature 221 240 9.5E-76 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS12805 b0c96722a46018d05b4e03ddb1479769 401 PRINTS PR00166 Aromatic amino acid permease signature 336 355 9.5E-76 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS12805 b0c96722a46018d05b4e03ddb1479769 401 PRINTS PR00166 Aromatic amino acid permease signature 10 33 9.5E-76 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS12805 b0c96722a46018d05b4e03ddb1479769 401 PRINTS PR00166 Aromatic amino acid permease signature 148 168 9.5E-76 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS12805 b0c96722a46018d05b4e03ddb1479769 401 PRINTS PR00166 Aromatic amino acid permease signature 37 56 9.5E-76 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS12805 b0c96722a46018d05b4e03ddb1479769 401 TIGRFAM TIGR00837 araaP: aromatic amino acid transport protein 7 383 7.7E-120 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS12805 b0c96722a46018d05b4e03ddb1479769 401 Pfam PF03222 Tryptophan/tyrosine permease family 3 389 1.5E-118 T 29-03-2018 IPR018227 Amino acid/polyamine transporter 2 GO:0003333 MC49_RS13815 cc15e0970dab3587bf9adfc6fcc84c99 150 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 38 8.7E-6 T 29-03-2018 MC49_RS13815 cc15e0970dab3587bf9adfc6fcc84c99 150 SUPERFAMILY SSF143120 1 39 2.22E-6 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM MC49_RS13815 cc15e0970dab3587bf9adfc6fcc84c99 150 Gene3D G3DSA:3.40.1620.10 1 113 4.4E-12 T 29-03-2018 MC49_RS13815 cc15e0970dab3587bf9adfc6fcc84c99 150 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 38 1.3E-7 T 29-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM MC49_RS08130 4f547652373017b23e7110852951c4e4 573 Gene3D G3DSA:3.30.930.10 11 460 1.1E-99 T 29-03-2018 MC49_RS08130 4f547652373017b23e7110852951c4e4 573 PIRSF PIRSF001535 1 573 6.8E-270 T 29-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 MC49_RS08130 4f547652373017b23e7110852951c4e4 573 Pfam PF03129 Anticodon binding domain 475 569 4.8E-21 T 29-03-2018 IPR004154 Anticodon-binding MC49_RS08130 4f547652373017b23e7110852951c4e4 573 SUPERFAMILY SSF55681 407 478 1.51E-104 T 29-03-2018 MC49_RS08130 4f547652373017b23e7110852951c4e4 573 SUPERFAMILY SSF55681 10 237 1.51E-104 T 29-03-2018 MC49_RS08130 4f547652373017b23e7110852951c4e4 573 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 9.6E-18 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MC49_RS08130 4f547652373017b23e7110852951c4e4 573 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 9.6E-18 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MC49_RS08130 4f547652373017b23e7110852951c4e4 573 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 9.6E-18 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MC49_RS08130 4f547652373017b23e7110852951c4e4 573 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 9.6E-18 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MC49_RS08130 4f547652373017b23e7110852951c4e4 573 SUPERFAMILY SSF55826 219 390 1.44E-29 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MC49_RS08130 4f547652373017b23e7110852951c4e4 573 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 459 8.6E-51 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MC49_RS08130 4f547652373017b23e7110852951c4e4 573 SUPERFAMILY SSF52954 462 570 2.13E-32 T 29-03-2018 IPR004154 Anticodon-binding MC49_RS08130 4f547652373017b23e7110852951c4e4 573 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 568 1.9E-263 T 29-03-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 MC49_RS08130 4f547652373017b23e7110852951c4e4 573 Gene3D G3DSA:3.40.50.800 461 573 7.8E-31 T 29-03-2018 IPR004154 Anticodon-binding MC49_RS08130 4f547652373017b23e7110852951c4e4 573 Pfam PF04073 Aminoacyl-tRNA editing domain 257 376 9.1E-25 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MC49_RS08130 4f547652373017b23e7110852951c4e4 573 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 571 42.173 T 29-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 MC49_RS04050 7bc47a348b979cf01314e0f5982c6ec2 118 Gene3D G3DSA:4.10.910.10 67 84 1.1E-18 T 29-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04050 7bc47a348b979cf01314e0f5982c6ec2 118 Gene3D G3DSA:1.10.8.50 1 66 6.5E-21 T 29-03-2018 MC49_RS04050 7bc47a348b979cf01314e0f5982c6ec2 118 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 29-03-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04050 7bc47a348b979cf01314e0f5982c6ec2 118 SUPERFAMILY SSF46946 2 114 6.06E-47 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 MC49_RS04050 7bc47a348b979cf01314e0f5982c6ec2 118 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 118 26.238 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04050 7bc47a348b979cf01314e0f5982c6ec2 118 Pfam PF00416 Ribosomal protein S13/S18 3 108 2.1E-34 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04050 7bc47a348b979cf01314e0f5982c6ec2 118 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 9.7E-54 T 29-03-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS04050 7bc47a348b979cf01314e0f5982c6ec2 118 PIRSF PIRSF002134 1 118 1.7E-42 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04050 7bc47a348b979cf01314e0f5982c6ec2 118 Gene3D G3DSA:4.10.910.10 85 118 1.2E-26 T 29-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS13485 d920b6de5d34d4a64cdc23ea7dc0d97d 427 Gene3D G3DSA:2.30.30.60 205 255 1.1E-9 T 29-03-2018 MC49_RS13485 d920b6de5d34d4a64cdc23ea7dc0d97d 427 SUPERFAMILY SSF50182 189 255 3.92E-12 T 29-03-2018 IPR010920 LSM domain MC49_RS13485 d920b6de5d34d4a64cdc23ea7dc0d97d 427 Pfam PF00924 Mechanosensitive ion channel 146 394 1.0E-51 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MC49_RS18945 ead2edb304596b0c123b83c47c1f5b78 192 Pfam PF04264 YceI-like domain 27 183 6.4E-39 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MC49_RS18945 ead2edb304596b0c123b83c47c1f5b78 192 Gene3D G3DSA:2.40.128.110 19 190 1.2E-48 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MC49_RS18945 ead2edb304596b0c123b83c47c1f5b78 192 SMART SM00867 26 190 3.1E-67 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MC49_RS18945 ead2edb304596b0c123b83c47c1f5b78 192 SUPERFAMILY SSF101874 23 191 6.28E-53 T 29-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MC49_RS14175 b05e11e48bfbff82739ff5252b0de15c 338 SUPERFAMILY SSF53822 25 338 6.12E-82 T 29-03-2018 IPR028082 Periplasmic binding protein-like I MC49_RS14175 b05e11e48bfbff82739ff5252b0de15c 338 Gene3D G3DSA:3.40.50.2300 143 338 7.2E-22 T 29-03-2018 MC49_RS14175 b05e11e48bfbff82739ff5252b0de15c 338 Gene3D G3DSA:3.40.50.2300 5 142 1.3E-15 T 29-03-2018 MC49_RS14175 b05e11e48bfbff82739ff5252b0de15c 338 Pfam PF13407 Periplasmic binding protein domain 28 283 5.4E-52 T 29-03-2018 IPR025997 Periplasmic binding protein MC49_RS13000 9ddaddf44cfa33b5875e12b8f918f054 145 Pfam PF06530 Phage antitermination protein Q 2 121 3.9E-28 T 29-03-2018 IPR010534 Bacteriophage 933W, GpQ GO:0003677|GO:0060567 MC49_RS17275 488c1c0171fce85eaa982bbf5b49713f 231 Pfam PF00849 RNA pseudouridylate synthase 62 192 2.9E-16 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS17275 488c1c0171fce85eaa982bbf5b49713f 231 SMART SM00363 1 69 2.2E-7 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MC49_RS17275 488c1c0171fce85eaa982bbf5b49713f 231 SUPERFAMILY SSF55174 1 55 1.19E-12 T 29-03-2018 MC49_RS17275 488c1c0171fce85eaa982bbf5b49713f 231 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 99 113 - T 29-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 MC49_RS17275 488c1c0171fce85eaa982bbf5b49713f 231 SUPERFAMILY SSF55120 61 227 4.8E-45 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS17275 488c1c0171fce85eaa982bbf5b49713f 231 Gene3D G3DSA:3.10.290.10 1 54 2.1E-12 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MC49_RS17275 488c1c0171fce85eaa982bbf5b49713f 231 Pfam PF01479 S4 domain 1 47 1.0E-7 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 MC49_RS17275 488c1c0171fce85eaa982bbf5b49713f 231 Gene3D G3DSA:3.30.70.580 55 140 7.5E-15 T 29-03-2018 MC49_RS17275 488c1c0171fce85eaa982bbf5b49713f 231 Gene3D G3DSA:3.30.70.1560 141 209 2.5E-25 T 29-03-2018 MC49_RS17275 488c1c0171fce85eaa982bbf5b49713f 231 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 224 5.3E-55 T 29-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 MC49_RS02165 136442e0cf20f15f07342b3114527066 382 SUPERFAMILY SSF46785 261 380 5.44E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS02165 136442e0cf20f15f07342b3114527066 382 Pfam PF07515 Putative conjugal transfer nickase/helicase TraI C-term 264 378 1.2E-17 T 29-03-2018 IPR011093 Putative conjugal transfer nickase/helicase TraI, C-terminal MC49_RS02165 136442e0cf20f15f07342b3114527066 382 TIGRFAM TIGR03760 ICE_TraI_Pfluor: integrating conjugative element relaxase, PFGI-1 class 23 232 1.9E-69 T 29-03-2018 IPR022391 Integrating conjugative element relaxase, PFGI-1 class MC49_RS02165 136442e0cf20f15f07342b3114527066 382 Pfam PF07514 Putative helicase 23 238 8.3E-41 T 29-03-2018 IPR011119 Uncharacterised domain, helicase/relaxase, putative MC49_RS02165 136442e0cf20f15f07342b3114527066 382 Gene3D G3DSA:2.40.10.200 281 380 7.6E-17 T 29-03-2018 MC49_RS16340 ca809b5b60d63043e84e06b917eafcb9 349 SUPERFAMILY SSF51569 57 242 2.56E-66 T 29-03-2018 MC49_RS16340 ca809b5b60d63043e84e06b917eafcb9 349 SUPERFAMILY SSF51569 270 343 2.56E-66 T 29-03-2018 MC49_RS16340 ca809b5b60d63043e84e06b917eafcb9 349 SMART SM01133 68 325 1.6E-42 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 MC49_RS16340 ca809b5b60d63043e84e06b917eafcb9 349 Gene3D G3DSA:3.20.20.70 52 346 2.8E-66 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS16340 ca809b5b60d63043e84e06b917eafcb9 349 Pfam PF01791 DeoC/LacD family aldolase 69 325 1.0E-69 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 MC49_RS17430 8eb7ba9b604d9d5913094aa89d59ba0e 512 Pfam PF03321 GH3 auxin-responsive promoter 22 499 1.1E-75 T 29-03-2018 IPR004993 GH3 family Reactome: R-HSA-6798695 MC49_RS16975 55a7d36dd081a45ddb13130e2549df24 800 Pfam PF13954 PapC N-terminal domain 27 175 9.3E-28 T 29-03-2018 IPR025885 PapC, N-terminal domain GO:0005515 MC49_RS16975 55a7d36dd081a45ddb13130e2549df24 800 Pfam PF00577 Outer membrane usher protein 452 711 4.8E-44 T 29-03-2018 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 MC49_RS16975 55a7d36dd081a45ddb13130e2549df24 800 Pfam PF00577 Outer membrane usher protein 193 446 7.5E-70 T 29-03-2018 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 MC49_RS16975 55a7d36dd081a45ddb13130e2549df24 800 Pfam PF13953 PapC C-terminal domain 722 787 1.7E-17 T 29-03-2018 IPR025949 PapC-like, C-terminal domain MC49_RS16975 55a7d36dd081a45ddb13130e2549df24 800 SUPERFAMILY SSF141729 56 168 3.4E-18 T 29-03-2018 MC49_RS18225 99ff69752da0e13a031d4879359319ac 315 Gene3D G3DSA:1.20.1510.10 26 225 1.9E-50 T 29-03-2018 MC49_RS18225 99ff69752da0e13a031d4879359319ac 315 SUPERFAMILY SSF160240 229 306 7.85E-23 T 29-03-2018 MC49_RS18225 99ff69752da0e13a031d4879359319ac 315 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 28 306 1.6E-72 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MC49_RS18225 99ff69752da0e13a031d4879359319ac 315 Gene3D G3DSA:3.30.70.1350 226 309 1.6E-22 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain MC49_RS18225 99ff69752da0e13a031d4879359319ac 315 Pfam PF01545 Cation efflux family 32 225 4.2E-49 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MC49_RS18225 99ff69752da0e13a031d4879359319ac 315 SUPERFAMILY SSF161111 27 226 2.35E-56 T 29-03-2018 MC49_RS18225 99ff69752da0e13a031d4879359319ac 315 Pfam PF16916 Dimerisation domain of Zinc Transporter 230 306 1.1E-24 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain MC49_RS10370 ea5b346dd09b2c0d18a54dede06964af 238 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 5 111 4.4E-30 T 29-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 MC49_RS10370 ea5b346dd09b2c0d18a54dede06964af 238 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 7 230 3.1E-90 T 29-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 MC49_RS10370 ea5b346dd09b2c0d18a54dede06964af 238 Gene3D G3DSA:3.10.20.30 1 106 2.8E-33 T 29-03-2018 IPR012675 Beta-grasp domain MC49_RS10370 ea5b346dd09b2c0d18a54dede06964af 238 Gene3D G3DSA:1.10.1060.10 107 238 2.0E-30 T 29-03-2018 MC49_RS10370 ea5b346dd09b2c0d18a54dede06964af 238 SUPERFAMILY SSF54292 1 106 3.01E-30 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MC49_RS10370 ea5b346dd09b2c0d18a54dede06964af 238 SUPERFAMILY SSF46548 107 236 1.43E-39 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MC49_RS10370 ea5b346dd09b2c0d18a54dede06964af 238 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 149 160 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MC49_RS10370 ea5b346dd09b2c0d18a54dede06964af 238 Pfam PF13534 4Fe-4S dicluster domain 148 221 3.1E-10 T 29-03-2018 MC49_RS09895 dcd2f72528b3675c6dd743ce789de10f 364 Pfam PF00793 DAHP synthetase I family 44 342 2.3E-103 T 29-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 MC49_RS09895 dcd2f72528b3675c6dd743ce789de10f 364 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 9 350 1.9E-163 T 29-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 MC49_RS09895 dcd2f72528b3675c6dd743ce789de10f 364 Gene3D G3DSA:3.20.20.70 11 357 1.6E-128 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS09895 dcd2f72528b3675c6dd743ce789de10f 364 PIRSF PIRSF001361 1 356 3.4E-160 T 29-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 MC49_RS09895 dcd2f72528b3675c6dd743ce789de10f 364 SUPERFAMILY SSF51569 11 348 9.07E-136 T 29-03-2018 MC49_RS02415 585c73ecc5c62336b496d201488183e4 119 Pfam PF01381 Helix-turn-helix 20 72 1.1E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS02415 585c73ecc5c62336b496d201488183e4 119 SMART SM00530 17 72 1.8E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS02415 585c73ecc5c62336b496d201488183e4 119 SUPERFAMILY SSF47413 4 79 2.82E-20 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS02415 585c73ecc5c62336b496d201488183e4 119 Gene3D G3DSA:1.10.260.40 1 77 4.0E-16 T 29-03-2018 MC49_RS08845 b9eba028b6bb680c943de100ec8cc8e9 406 Gene3D G3DSA:3.30.1490.20 143 211 6.4E-19 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 MC49_RS08845 b9eba028b6bb680c943de100ec8cc8e9 406 Gene3D G3DSA:3.30.470.20 212 404 1.5E-36 T 29-03-2018 MC49_RS08845 b9eba028b6bb680c943de100ec8cc8e9 406 Gene3D G3DSA:3.40.50.20 28 126 4.0E-20 T 29-03-2018 MC49_RS08845 b9eba028b6bb680c943de100ec8cc8e9 406 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 28 404 3.4E-175 T 29-03-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 MC49_RS08845 b9eba028b6bb680c943de100ec8cc8e9 406 SUPERFAMILY SSF56059 127 329 2.47E-55 T 29-03-2018 MC49_RS08845 b9eba028b6bb680c943de100ec8cc8e9 406 SUPERFAMILY SSF52440 17 126 4.03E-35 T 29-03-2018 IPR016185 Pre-ATP-grasp domain MC49_RS08845 b9eba028b6bb680c943de100ec8cc8e9 406 Pfam PF02222 ATP-grasp domain 137 309 1.3E-54 T 29-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type MC49_RS08845 b9eba028b6bb680c943de100ec8cc8e9 406 SUPERFAMILY SSF51246 334 404 2.04E-16 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MC49_RS08845 b9eba028b6bb680c943de100ec8cc8e9 406 Hamap MF_01643 Phosphoribosylglycinamide formyltransferase 2 [purT]. 22 405 50.418 T 29-03-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 MC49_RS14555 c936ae7e5d22257856313dd1d49ab31f 276 SUPERFAMILY SSF56784 8 214 6.3E-14 T 29-03-2018 IPR023214 HAD-like domain MC49_RS14555 c936ae7e5d22257856313dd1d49ab31f 276 Gene3D G3DSA:3.40.50.1000 1 230 5.4E-9 T 29-03-2018 IPR023214 HAD-like domain MC49_RS14555 c936ae7e5d22257856313dd1d49ab31f 276 Pfam PF12710 haloacid dehalogenase-like hydrolase 10 211 1.2E-11 T 29-03-2018 MC49_RS17990 844d4bc0b1e6a7e107acb8daf86d929a 140 SMART SM00347 22 122 1.2E-22 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MC49_RS17990 844d4bc0b1e6a7e107acb8daf86d929a 140 Gene3D G3DSA:1.10.10.10 4 138 1.6E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS17990 844d4bc0b1e6a7e107acb8daf86d929a 140 Pfam PF01047 MarR family 30 86 2.3E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MC49_RS17990 844d4bc0b1e6a7e107acb8daf86d929a 140 SUPERFAMILY SSF46785 18 137 1.31E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS17990 844d4bc0b1e6a7e107acb8daf86d929a 140 PRINTS PR00598 Bacterial regulatory protein MarR family signature 46 62 7.0E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MC49_RS17990 844d4bc0b1e6a7e107acb8daf86d929a 140 PRINTS PR00598 Bacterial regulatory protein MarR family signature 82 98 7.0E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MC49_RS17990 844d4bc0b1e6a7e107acb8daf86d929a 140 PRINTS PR00598 Bacterial regulatory protein MarR family signature 112 132 7.0E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MC49_RS07030 056101fdc34869e753246c300b3cc596 185 Pfam PF01381 Helix-turn-helix 13 66 1.8E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS07030 056101fdc34869e753246c300b3cc596 185 SUPERFAMILY SSF51182 102 171 2.97E-12 T 29-03-2018 IPR011051 RmlC-like cupin domain MC49_RS07030 056101fdc34869e753246c300b3cc596 185 SMART SM00530 11 66 2.8E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS07030 056101fdc34869e753246c300b3cc596 185 Gene3D G3DSA:1.10.260.40 2 100 6.6E-19 T 29-03-2018 MC49_RS07030 056101fdc34869e753246c300b3cc596 185 Gene3D G3DSA:2.60.120.10 101 179 2.5E-8 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MC49_RS07030 056101fdc34869e753246c300b3cc596 185 SUPERFAMILY SSF47413 5 73 2.73E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS01645 c6737aeaaf656d46e93fa226d4593837 481 Pfam PF01523 Putative modulator of DNA gyrase 35 332 1.6E-69 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 MC49_RS01645 c6737aeaaf656d46e93fa226d4593837 481 SUPERFAMILY SSF111283 19 480 3.53E-132 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 MC49_RS01645 c6737aeaaf656d46e93fa226d4593837 481 PIRSF PIRSF004919 15 481 1.8E-147 T 29-03-2018 IPR025502 TldD MC49_RS01645 c6737aeaaf656d46e93fa226d4593837 481 Gene3D G3DSA:3.30.2290.10 13 240 8.7E-56 T 29-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain MC49_RS12725 d693469085ce60d56c35638f972c9da6 497 Pfam PF00474 Sodium:solute symporter family 37 438 9.7E-134 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 MC49_RS12725 d693469085ce60d56c35638f972c9da6 497 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 8 490 2.5E-220 T 29-03-2018 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 MC49_RS12725 d693469085ce60d56c35638f972c9da6 497 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 158 183 - T 29-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 MC49_RS12725 d693469085ce60d56c35638f972c9da6 497 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 37 438 4.2E-117 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 MC49_RS17225 768801d926e3bde2e9b422cb471d5c3d 312 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 39 63 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MC49_RS17225 768801d926e3bde2e9b422cb471d5c3d 312 SUPERFAMILY SSF53613 7 292 4.37E-69 T 29-03-2018 IPR029056 Ribokinase-like MC49_RS17225 768801d926e3bde2e9b422cb471d5c3d 312 Gene3D G3DSA:2.20.150.10 12 46 1.5E-12 T 29-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain MC49_RS17225 768801d926e3bde2e9b422cb471d5c3d 312 Pfam PF00294 pfkB family carbohydrate kinase 14 292 3.5E-63 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB MC49_RS17225 768801d926e3bde2e9b422cb471d5c3d 312 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 5 308 5.3E-103 T 29-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 MC49_RS17225 768801d926e3bde2e9b422cb471d5c3d 312 Gene3D G3DSA:3.40.1190.20 47 312 5.2E-51 T 29-03-2018 IPR029056 Ribokinase-like MC49_RS17225 768801d926e3bde2e9b422cb471d5c3d 312 PIRSF PIRSF000535 2 311 9.7E-111 T 29-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 MC49_RS17225 768801d926e3bde2e9b422cb471d5c3d 312 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 249 262 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MC49_RS17225 768801d926e3bde2e9b422cb471d5c3d 312 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 5 308 3.1E-104 T 29-03-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 MC49_RS08860 b668ef2df4d0c909ae61084244204c24 716 Pfam PF02554 Carbon starvation protein CstA 34 406 2.4E-161 T 29-03-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 MC49_RS08860 b668ef2df4d0c909ae61084244204c24 716 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 486 614 5.0E-34 T 29-03-2018 IPR025299 CstA, C-terminal domain MC49_RS18050 7586d5209aed917b77029b15ee02528b 256 Gene3D G3DSA:3.40.630.30 70 256 1.9E-18 T 29-03-2018 MC49_RS18050 7586d5209aed917b77029b15ee02528b 256 Pfam PF13673 Acetyltransferase (GNAT) domain 160 250 1.1E-10 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MC49_RS18050 7586d5209aed917b77029b15ee02528b 256 SUPERFAMILY SSF55729 71 247 9.14E-22 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS09710 106416ea5a60b3b313c55e7bedbb3f48 412 TIGRFAM TIGR01937 nqrB: NADH:ubiquinone oxidoreductase, Na(+)-translocating, B subunit 3 408 2.5E-191 T 29-03-2018 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 MC49_RS09710 106416ea5a60b3b313c55e7bedbb3f48 412 Pfam PF03116 NQR2, RnfD, RnfE family 42 405 3.8E-105 T 29-03-2018 IPR004338 NADH-quinone reductase NQR2/RnfD GO:0006810|GO:0016020 MC49_RS09710 106416ea5a60b3b313c55e7bedbb3f48 412 Hamap MF_00426 Na(+)-translocating NADH-quinone reductase subunit B [nqrB]. 2 412 36.385 T 29-03-2018 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 MC49_RS09710 106416ea5a60b3b313c55e7bedbb3f48 412 PIRSF PIRSF016055 1 412 3.1E-197 T 29-03-2018 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 MC49_RS10620 66f438f844303010a7d60eeb5b3c05e5 81 Gene3D G3DSA:3.10.20.30 1 81 1.7E-21 T 29-03-2018 IPR012675 Beta-grasp domain MC49_RS10620 66f438f844303010a7d60eeb5b3c05e5 81 SUPERFAMILY SSF54285 1 81 1.2E-24 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp MC49_RS10620 66f438f844303010a7d60eeb5b3c05e5 81 Pfam PF02597 ThiS family 4 81 2.6E-21 T 29-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 MC49_RS10620 66f438f844303010a7d60eeb5b3c05e5 81 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 2 81 1.4E-23 T 29-03-2018 IPR010034 Molybdopterin converting factor, subunit 1 GO:0006777 Reactome: R-HSA-947581 MC49_RS12580 8740761c0ec47a31d21c389913deef90 261 Pfam PF01311 Bacterial export proteins, family 1 15 246 1.6E-62 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 MC49_RS12580 8740761c0ec47a31d21c389913deef90 261 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 16 252 8.3E-68 T 29-03-2018 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 MC49_RS12580 8740761c0ec47a31d21c389913deef90 261 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 22 43 3.9E-28 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 MC49_RS12580 8740761c0ec47a31d21c389913deef90 261 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 202 221 3.9E-28 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 MC49_RS12580 8740761c0ec47a31d21c389913deef90 261 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 80 99 3.9E-28 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 MC49_RS12580 8740761c0ec47a31d21c389913deef90 261 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 180 202 3.9E-28 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 MC49_RS15710 cceb780223b95d786db9d8553369784d 152 Gene3D G3DSA:3.10.450.160 27 152 7.5E-26 T 29-03-2018 MC49_RS04135 4191c72c5e0e251c6ae3f8ea0e92989f 110 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 1.2E-50 T 29-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS04135 4191c72c5e0e251c6ae3f8ea0e92989f 110 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 29.383 T 29-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS04135 4191c72c5e0e251c6ae3f8ea0e92989f 110 Gene3D G3DSA:3.90.470.10 1 110 1.4E-43 T 29-03-2018 MC49_RS04135 4191c72c5e0e251c6ae3f8ea0e92989f 110 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 29-03-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04135 4191c72c5e0e251c6ae3f8ea0e92989f 110 SUPERFAMILY SSF54843 1 109 7.72E-44 T 29-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 MC49_RS04135 4191c72c5e0e251c6ae3f8ea0e92989f 110 Pfam PF00237 Ribosomal protein L22p/L17e 5 107 8.5E-39 T 29-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 MC49_RS16365 1a9987596200128d0ba73f13f05a2e7e 468 ProSitePatterns PS00218 Amino acid permeases signature. 45 75 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 MC49_RS16365 1a9987596200128d0ba73f13f05a2e7e 468 PIRSF PIRSF006060 1 468 9.4E-73 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MC49_RS16365 1a9987596200128d0ba73f13f05a2e7e 468 Pfam PF00324 Amino acid permease 20 466 2.5E-105 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 MC49_RS17300 56158414dc8708083ed2154c53be8dfe 589 Pfam PF11893 Domain of unknown function (DUF3413) 7 251 7.9E-103 T 29-03-2018 IPR024588 Inner membrane protein YejM, N-terminal MC49_RS17300 56158414dc8708083ed2154c53be8dfe 589 Gene3D G3DSA:3.40.720.10 257 545 3.1E-28 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 MC49_RS17300 56158414dc8708083ed2154c53be8dfe 589 Pfam PF00884 Sulfatase 418 502 5.6E-10 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 MC49_RS17300 56158414dc8708083ed2154c53be8dfe 589 Pfam PF00884 Sulfatase 276 404 5.1E-6 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 MC49_RS17300 56158414dc8708083ed2154c53be8dfe 589 SUPERFAMILY SSF53649 257 561 3.74E-36 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MC49_RS17300 56158414dc8708083ed2154c53be8dfe 589 PIRSF PIRSF004950 413 588 5.8E-48 T 29-03-2018 IPR012159 Inner membrane protein YejM MC49_RS17300 56158414dc8708083ed2154c53be8dfe 589 PIRSF PIRSF004950 6 417 5.7E-138 T 29-03-2018 IPR012159 Inner membrane protein YejM MC49_RS01500 3d71dda80864745b247461aa29da8ac7 265 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 259 9.1E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS01500 3d71dda80864745b247461aa29da8ac7 265 Gene3D G3DSA:1.10.3720.10 13 262 4.7E-32 T 29-03-2018 MC49_RS01500 3d71dda80864745b247461aa29da8ac7 265 SUPERFAMILY SSF161098 65 251 1.7E-35 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS16200 7f9686628af36a4f8af7a1e9f408a3b4 588 SUPERFAMILY SSF53474 215 285 9.38E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS16200 7f9686628af36a4f8af7a1e9f408a3b4 588 SUPERFAMILY SSF53474 12 148 9.38E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS16200 7f9686628af36a4f8af7a1e9f408a3b4 588 Pfam PF12147 Putative methyltransferase 280 587 1.0E-133 T 29-03-2018 IPR022744 Methyltransferase domain, putative MC49_RS16200 7f9686628af36a4f8af7a1e9f408a3b4 588 Pfam PF12146 Serine aminopeptidase, S33 36 272 1.4E-63 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 MC49_RS16200 7f9686628af36a4f8af7a1e9f408a3b4 588 Gene3D G3DSA:3.40.50.150 362 586 4.2E-13 T 29-03-2018 MC49_RS16200 7f9686628af36a4f8af7a1e9f408a3b4 588 SUPERFAMILY SSF53335 405 579 4.57E-15 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS16200 7f9686628af36a4f8af7a1e9f408a3b4 588 Gene3D G3DSA:3.40.50.1820 4 297 4.0E-35 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS15970 949c9f9eb6520c72662f765b7efbeb7d 118 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS15970 949c9f9eb6520c72662f765b7efbeb7d 118 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 72 5.0E-14 T 29-03-2018 MC49_RS15970 949c9f9eb6520c72662f765b7efbeb7d 118 SUPERFAMILY SSF74731 3 117 8.63E-51 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS15970 949c9f9eb6520c72662f765b7efbeb7d 118 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 1.4E-53 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS15970 949c9f9eb6520c72662f765b7efbeb7d 118 Pfam PF00453 Ribosomal protein L20 3 109 1.9E-49 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS15970 949c9f9eb6520c72662f765b7efbeb7d 118 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.2E-42 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS15970 949c9f9eb6520c72662f765b7efbeb7d 118 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.2E-42 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS15970 949c9f9eb6520c72662f765b7efbeb7d 118 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.2E-42 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS15970 949c9f9eb6520c72662f765b7efbeb7d 118 Gene3D G3DSA:1.10.1900.20 55 116 8.1E-30 T 29-03-2018 IPR035566 Ribosomal protein L20 C-terminal domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS15970 949c9f9eb6520c72662f765b7efbeb7d 118 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 31.275 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS07465 90e5694734c07164944a0f580e5a0ce5 555 SUPERFAMILY SSF52540 12 243 1.84E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS07465 90e5694734c07164944a0f580e5a0ce5 555 SMART SM00382 348 522 1.4E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS07465 90e5694734c07164944a0f580e5a0ce5 555 SMART SM00382 31 236 3.5E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS07465 90e5694734c07164944a0f580e5a0ce5 555 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS07465 90e5694734c07164944a0f580e5a0ce5 555 Gene3D G3DSA:3.40.50.300 290 552 3.4E-58 T 29-03-2018 MC49_RS07465 90e5694734c07164944a0f580e5a0ce5 555 Pfam PF00005 ABC transporter 340 473 4.7E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS07465 90e5694734c07164944a0f580e5a0ce5 555 Pfam PF00005 ABC transporter 22 191 9.9E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS07465 90e5694734c07164944a0f580e5a0ce5 555 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 2 553 9.9E-294 T 29-03-2018 IPR022374 ABC transporter, ATP-binding protein, ChvD MC49_RS07465 90e5694734c07164944a0f580e5a0ce5 555 SUPERFAMILY SSF52540 302 532 2.27E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS07465 90e5694734c07164944a0f580e5a0ce5 555 Pfam PF12848 ABC transporter 230 306 1.3E-12 T 29-03-2018 IPR032781 ABC-transporter extension domain MC49_RS07465 90e5694734c07164944a0f580e5a0ce5 555 Gene3D G3DSA:3.40.50.300 12 289 3.5E-57 T 29-03-2018 MC49_RS12310 deab1ee1f86487a062f729590485c2d3 113 Pfam PF01588 Putative tRNA binding domain 16 110 2.8E-16 T 29-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 MC49_RS12310 deab1ee1f86487a062f729590485c2d3 113 Gene3D G3DSA:2.40.50.140 2 113 4.3E-21 T 29-03-2018 MC49_RS12310 deab1ee1f86487a062f729590485c2d3 113 SUPERFAMILY SSF50249 6 112 4.28E-31 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS12310 deab1ee1f86487a062f729590485c2d3 113 TIGRFAM TIGR02222 chap_CsaA: export-related chaperone protein CsaA 8 112 8.4E-44 T 29-03-2018 IPR008231 Probable chaperone CsaA MC49_RS15390 2abcc108202c30f097765075458ebe65 269 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 265 2.7E-104 T 29-03-2018 MC49_RS15390 2abcc108202c30f097765075458ebe65 269 Gene3D G3DSA:3.60.10.10 1 267 8.5E-53 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase MC49_RS15390 2abcc108202c30f097765075458ebe65 269 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 258 9.1E-24 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase MC49_RS15390 2abcc108202c30f097765075458ebe65 269 SUPERFAMILY SSF56219 1 267 1.07E-87 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase MC49_RS15390 2abcc108202c30f097765075458ebe65 269 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 266 1.3E-89 T 29-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 MC49_RS15390 2abcc108202c30f097765075458ebe65 269 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 27 36 - T 29-03-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 MC49_RS15390 2abcc108202c30f097765075458ebe65 269 ProSitePatterns PS00728 AP endonucleases family 1 signature 3. 222 233 - T 29-03-2018 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 MC49_RS16860 678cc27d610b24b77c47d883185b7cc3 73 Pfam PF04325 Protein of unknown function (DUF465) 19 66 2.0E-16 T 29-03-2018 IPR007420 Protein of unknown function DUF465 MC49_RS16860 678cc27d610b24b77c47d883185b7cc3 73 Gene3D G3DSA:1.10.287.40 2 69 4.3E-5 T 29-03-2018 MC49_RS03365 4473778776519c5da5cde1efd5718f3a 314 Gene3D G3DSA:3.30.2350.10 9 226 6.1E-80 T 29-03-2018 MC49_RS03365 4473778776519c5da5cde1efd5718f3a 314 Pfam PF09157 Pseudouridine synthase II TruB, C-terminal 251 309 2.1E-16 T 29-03-2018 IPR015240 tRNA pseudouridine synthase II, TruB, subfamily 1, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS03365 4473778776519c5da5cde1efd5718f3a 314 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 10 309 18.685 T 29-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS03365 4473778776519c5da5cde1efd5718f3a 314 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 10 218 3.6E-89 T 29-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS03365 4473778776519c5da5cde1efd5718f3a 314 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 32 179 7.6E-57 T 29-03-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 MC49_RS03365 4473778776519c5da5cde1efd5718f3a 314 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 180 247 2.4E-24 T 29-03-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 MC49_RS03365 4473778776519c5da5cde1efd5718f3a 314 SUPERFAMILY SSF88697 250 310 3.53E-12 T 29-03-2018 IPR015947 PUA-like domain MC49_RS03365 4473778776519c5da5cde1efd5718f3a 314 Gene3D G3DSA:2.30.130.10 249 313 1.2E-13 T 29-03-2018 IPR002478 PUA domain GO:0003723 MC49_RS03365 4473778776519c5da5cde1efd5718f3a 314 SUPERFAMILY SSF55120 9 248 4.6E-82 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS06285 fd03a3e5497673169613650d50208880 291 ProSitePatterns PS00567 Phosphoribulokinase signature. 164 177 - T 29-03-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 MC49_RS06285 fd03a3e5497673169613650d50208880 291 SUPERFAMILY SSF52540 4 285 2.58E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS06285 fd03a3e5497673169613650d50208880 291 PRINTS PR00478 Phosphoribulokinase family signature 12 29 5.6E-29 T 29-03-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 MC49_RS06285 fd03a3e5497673169613650d50208880 291 PRINTS PR00478 Phosphoribulokinase family signature 126 144 5.6E-29 T 29-03-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 MC49_RS06285 fd03a3e5497673169613650d50208880 291 PRINTS PR00478 Phosphoribulokinase family signature 164 181 5.6E-29 T 29-03-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 MC49_RS06285 fd03a3e5497673169613650d50208880 291 PRINTS PR00478 Phosphoribulokinase family signature 182 205 5.6E-29 T 29-03-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 MC49_RS06285 fd03a3e5497673169613650d50208880 291 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 7 214 7.9E-73 T 29-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 MC49_RS06285 fd03a3e5497673169613650d50208880 291 Gene3D G3DSA:3.40.50.300 1 289 9.0E-43 T 29-03-2018 MC49_RS05720 4b383ed2ab6cb9f8e04334361cb182a1 229 Pfam PF02348 Cytidylyltransferase 6 182 1.1E-20 T 29-03-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 MC49_RS05720 4b383ed2ab6cb9f8e04334361cb182a1 229 Gene3D G3DSA:3.90.550.10 1 228 4.3E-30 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MC49_RS05720 4b383ed2ab6cb9f8e04334361cb182a1 229 SUPERFAMILY SSF53448 1 226 9.3E-53 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MC49_RS10425 c9e8a181c053ee3f098b7fa0909d5995 457 Pfam PF07690 Major Facilitator Superfamily 12 401 3.9E-44 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS10425 c9e8a181c053ee3f098b7fa0909d5995 457 Gene3D G3DSA:1.20.1250.20 244 456 5.8E-19 T 29-03-2018 MC49_RS10425 c9e8a181c053ee3f098b7fa0909d5995 457 Gene3D G3DSA:1.20.1250.20 1 191 1.1E-30 T 29-03-2018 MC49_RS10425 c9e8a181c053ee3f098b7fa0909d5995 457 SUPERFAMILY SSF103473 240 444 7.85E-56 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS10425 c9e8a181c053ee3f098b7fa0909d5995 457 SUPERFAMILY SSF103473 3 193 7.85E-56 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS09855 5b6c39fe96087d978a54aa89bb0d89f3 171 Hamap MF_00091 S-ribosylhomocysteine lyase [luxS]. 1 159 34.567 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MC49_RS09855 5b6c39fe96087d978a54aa89bb0d89f3 171 PIRSF PIRSF006160 1 162 4.9E-63 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MC49_RS09855 5b6c39fe96087d978a54aa89bb0d89f3 171 Gene3D G3DSA:3.30.1360.80 3 161 1.1E-61 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MC49_RS09855 5b6c39fe96087d978a54aa89bb0d89f3 171 SUPERFAMILY SSF63411 4 161 1.19E-63 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MC49_RS09855 5b6c39fe96087d978a54aa89bb0d89f3 171 Pfam PF02664 S-Ribosylhomocysteinase (LuxS) 4 154 1.0E-59 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MC49_RS09855 5b6c39fe96087d978a54aa89bb0d89f3 171 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 121 140 5.3E-48 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MC49_RS09855 5b6c39fe96087d978a54aa89bb0d89f3 171 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 28 46 5.3E-48 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MC49_RS09855 5b6c39fe96087d978a54aa89bb0d89f3 171 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 5 23 5.3E-48 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MC49_RS09855 5b6c39fe96087d978a54aa89bb0d89f3 171 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 77 95 5.3E-48 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MC49_RS09855 5b6c39fe96087d978a54aa89bb0d89f3 171 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 49 67 5.3E-48 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MC49_RS09855 5b6c39fe96087d978a54aa89bb0d89f3 171 ProDom PD013172 LYASE SYNTHESIS LUXS AUTOINDUCER-2 PRODUCTION AUTOINDUCER S-RIBOSYLHOMOCYSTEINE AI-2 QUORUM SENSING 9 155 3.0E-70 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MC49_RS09410 87b925a000c95da7d918fec8b6208efb 187 SUPERFAMILY SSF54001 30 186 3.19E-25 T 29-03-2018 MC49_RS09410 87b925a000c95da7d918fec8b6208efb 187 Pfam PF05708 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family 30 186 1.7E-20 T 29-03-2018 IPR024453 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family MC49_RS09410 87b925a000c95da7d918fec8b6208efb 187 Gene3D G3DSA:3.90.1720.10 29 161 5.0E-23 T 29-03-2018 MC49_RS03370 7c0ed4f827937881d26af6a9e64c0069 136 Pfam PF02033 Ribosome-binding factor A 7 115 3.8E-30 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 MC49_RS03370 7c0ed4f827937881d26af6a9e64c0069 136 SUPERFAMILY SSF89919 2 110 2.88E-31 T 29-03-2018 IPR023799 Ribosome-binding factor A domain MC49_RS03370 7c0ed4f827937881d26af6a9e64c0069 136 Gene3D G3DSA:3.30.300.20 1 103 3.0E-32 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta MC49_RS03370 7c0ed4f827937881d26af6a9e64c0069 136 ProSitePatterns PS01319 Ribosome-binding factor A signature. 82 103 - T 29-03-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 MC49_RS03370 7c0ed4f827937881d26af6a9e64c0069 136 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 9 103 6.0E-38 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 MC49_RS03370 7c0ed4f827937881d26af6a9e64c0069 136 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 3 123 21.573 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 MC49_RS03370 7c0ed4f827937881d26af6a9e64c0069 136 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 121 2.5E-37 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 MC49_RS04105 199c344a0922fb94756cdc86fc342ede 104 SUPERFAMILY SSF50104 4 100 5.11E-33 T 29-03-2018 IPR008991 Translation protein SH3-like domain MC49_RS04105 199c344a0922fb94756cdc86fc342ede 104 SMART SM00739 4 31 0.0044 T 29-03-2018 IPR005824 KOW MC49_RS04105 199c344a0922fb94756cdc86fc342ede 104 Gene3D G3DSA:2.30.30.30 2 93 5.1E-30 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 MC49_RS04105 199c344a0922fb94756cdc86fc342ede 104 ProSitePatterns PS01108 Ribosomal protein L24 signature. 8 25 - T 29-03-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS04105 199c344a0922fb94756cdc86fc342ede 104 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 3 97 20.052 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS04105 199c344a0922fb94756cdc86fc342ede 104 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 39 103 1.6E-23 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS04105 199c344a0922fb94756cdc86fc342ede 104 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 3 103 2.2E-39 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS05900 58ec1a6b231fcf4b6c1e5f9ddb70546c 810 Pfam PF00742 Homoserine dehydrogenase 608 803 1.5E-44 T 29-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MC49_RS05900 58ec1a6b231fcf4b6c1e5f9ddb70546c 810 Gene3D G3DSA:3.40.50.720 454 629 3.9E-23 T 29-03-2018 MC49_RS05900 58ec1a6b231fcf4b6c1e5f9ddb70546c 810 Gene3D G3DSA:3.30.360.10 630 787 1.3E-52 T 29-03-2018 MC49_RS05900 58ec1a6b231fcf4b6c1e5f9ddb70546c 810 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 654 676 - T 29-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MC49_RS05900 58ec1a6b231fcf4b6c1e5f9ddb70546c 810 SUPERFAMILY SSF55347 608 791 1.7E-46 T 29-03-2018 MC49_RS05900 58ec1a6b231fcf4b6c1e5f9ddb70546c 810 Gene3D G3DSA:3.40.1160.10 8 280 5.3E-49 T 29-03-2018 MC49_RS05900 58ec1a6b231fcf4b6c1e5f9ddb70546c 810 PIRSF PIRSF000727 11 810 2.3E-284 T 29-03-2018 IPR011147 Bifunctional aspartokinase/homoserine dehydrogenase I GO:0004072|GO:0004412|GO:0009067|GO:0055114 KEGG: 00260+2.7.2.4+1.1.1.3|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4+1.1.1.3|KEGG: 00300+2.7.2.4+1.1.1.3|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 MC49_RS05900 58ec1a6b231fcf4b6c1e5f9ddb70546c 810 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 464 600 1.1E-19 T 29-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 MC49_RS05900 58ec1a6b231fcf4b6c1e5f9ddb70546c 810 SUPERFAMILY SSF51735 456 630 3.4E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS05900 58ec1a6b231fcf4b6c1e5f9ddb70546c 810 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 14 452 3.4E-62 T 29-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 MC49_RS05900 58ec1a6b231fcf4b6c1e5f9ddb70546c 810 SUPERFAMILY SSF53633 11 298 3.14E-55 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MC49_RS05900 58ec1a6b231fcf4b6c1e5f9ddb70546c 810 ProSitePatterns PS00324 Aspartokinase signature. 13 21 - T 29-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 MC49_RS05900 58ec1a6b231fcf4b6c1e5f9ddb70546c 810 Pfam PF00696 Amino acid kinase family 11 283 2.3E-43 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MC49_RS08380 c579768090559d0038bec5019c235f22 282 Gene3D G3DSA:3.40.50.300 2 245 7.7E-61 T 29-03-2018 MC49_RS08380 c579768090559d0038bec5019c235f22 282 Pfam PF00005 ABC transporter 22 170 3.0E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS08380 c579768090559d0038bec5019c235f22 282 SMART SM00382 31 218 1.9E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS08380 c579768090559d0038bec5019c235f22 282 TIGRFAM TIGR01166 cbiO: cobalt ABC transporter, ATP-binding protein 16 204 8.6E-82 T 29-03-2018 IPR005876 Cobalt transport protein ATP-binding subunit GO:0006824 MC49_RS08380 c579768090559d0038bec5019c235f22 282 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS08380 c579768090559d0038bec5019c235f22 282 SUPERFAMILY SSF52540 4 237 1.49E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS03835 41f06b3194683b9c63bef51a04a15649 358 Pfam PF00953 Glycosyl transferase family 4 71 226 1.2E-30 T 29-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 MC49_RS03835 41f06b3194683b9c63bef51a04a15649 358 Hamap MF_02030 Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase [wecA]. 4 349 27.745 T 29-03-2018 IPR012750 Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase GO:0000287|GO:0009103|GO:0009276|GO:0016021|GO:0016780|GO:0030145 MetaCyc: PWY-7290|MetaCyc: PWY-7530|MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819 MC49_RS03835 41f06b3194683b9c63bef51a04a15649 358 TIGRFAM TIGR02380 ECA_wecA: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase 3 346 2.6E-153 T 29-03-2018 IPR012750 Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase GO:0000287|GO:0009103|GO:0009276|GO:0016021|GO:0016780|GO:0030145 MetaCyc: PWY-7290|MetaCyc: PWY-7530|MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819 MC49_RS09250 8204078ee884ccb695a8ebfbe2218147 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 150 168 1.9E-30 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS09250 8204078ee884ccb695a8ebfbe2218147 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 233 250 1.9E-30 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS09250 8204078ee884ccb695a8ebfbe2218147 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 113 126 1.9E-30 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS09250 8204078ee884ccb695a8ebfbe2218147 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 177 193 1.9E-30 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS09250 8204078ee884ccb695a8ebfbe2218147 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 273 288 1.9E-30 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS09250 8204078ee884ccb695a8ebfbe2218147 340 Gene3D G3DSA:3.40.50.720 1 165 5.1E-64 T 29-03-2018 MC49_RS09250 8204078ee884ccb695a8ebfbe2218147 340 Gene3D G3DSA:3.30.360.10 166 319 8.6E-51 T 29-03-2018 MC49_RS09250 8204078ee884ccb695a8ebfbe2218147 340 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 105 8.0E-33 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS09250 8204078ee884ccb695a8ebfbe2218147 340 SUPERFAMILY SSF55347 156 318 6.85E-57 T 29-03-2018 MC49_RS09250 8204078ee884ccb695a8ebfbe2218147 340 TIGRFAM TIGR01532 E4PD_g-proteo: erythrose-4-phosphate dehydrogenase 4 329 1.2E-177 T 29-03-2018 IPR006422 D-erythrose-4-phosphate dehydrogenase GO:0005737|GO:0042823|GO:0048001|GO:0051287|GO:0055114 KEGG: 00750+1.2.1.72 MC49_RS09250 8204078ee884ccb695a8ebfbe2218147 340 SMART SM00846 3 156 4.3E-77 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS09250 8204078ee884ccb695a8ebfbe2218147 340 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 154 161 - T 29-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS09250 8204078ee884ccb695a8ebfbe2218147 340 SUPERFAMILY SSF51735 1 180 1.8E-54 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS09250 8204078ee884ccb695a8ebfbe2218147 340 PIRSF PIRSF000149 1 338 6.4E-130 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS09250 8204078ee884ccb695a8ebfbe2218147 340 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 161 317 2.0E-53 T 29-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MC49_RS09250 8204078ee884ccb695a8ebfbe2218147 340 Hamap MF_01640 D-erythrose-4-phosphate dehydrogenase [epd]. 2 338 64.086 T 29-03-2018 IPR006422 D-erythrose-4-phosphate dehydrogenase GO:0005737|GO:0042823|GO:0048001|GO:0051287|GO:0055114 KEGG: 00750+1.2.1.72 MC49_RS05345 416a808f4fc13ba68768cf7d39153fcd 46 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 3.6E-27 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS05345 416a808f4fc13ba68768cf7d39153fcd 46 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 16.163 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS05345 416a808f4fc13ba68768cf7d39153fcd 46 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 31 4.0E-11 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS05345 416a808f4fc13ba68768cf7d39153fcd 46 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 29-03-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS05345 416a808f4fc13ba68768cf7d39153fcd 46 Pfam PF00468 Ribosomal protein L34 1 44 1.7E-24 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS15640 0e52a1255eddc6eee5e076eaf83c0ab0 307 Gene3D G3DSA:3.40.50.720 1 129 3.0E-32 T 29-03-2018 MC49_RS15640 0e52a1255eddc6eee5e076eaf83c0ab0 307 SUPERFAMILY SSF51735 3 138 4.2E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS15640 0e52a1255eddc6eee5e076eaf83c0ab0 307 Gene3D G3DSA:3.30.360.10 130 305 1.0E-20 T 29-03-2018 MC49_RS15640 0e52a1255eddc6eee5e076eaf83c0ab0 307 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 121 6.9E-25 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 MC49_RS15640 0e52a1255eddc6eee5e076eaf83c0ab0 307 SUPERFAMILY SSF55347 123 267 1.8E-34 T 29-03-2018 MC49_RS03855 c9fd6a59d64e491fa7ba32a41ecc1a88 502 SUPERFAMILY SSF109604 307 496 3.77E-41 T 29-03-2018 MC49_RS03855 c9fd6a59d64e491fa7ba32a41ecc1a88 502 Gene3D G3DSA:3.30.420.40 1 120 4.8E-38 T 29-03-2018 MC49_RS03855 c9fd6a59d64e491fa7ba32a41ecc1a88 502 PIRSF PIRSF001267 1 496 6.9E-174 T 29-03-2018 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 MC49_RS03855 c9fd6a59d64e491fa7ba32a41ecc1a88 502 Gene3D G3DSA:3.30.420.150 121 299 1.8E-32 T 29-03-2018 MC49_RS03855 c9fd6a59d64e491fa7ba32a41ecc1a88 502 SUPERFAMILY SSF53067 7 128 8.09E-36 T 29-03-2018 MC49_RS03855 c9fd6a59d64e491fa7ba32a41ecc1a88 502 SUPERFAMILY SSF53067 132 300 2.37E-41 T 29-03-2018 MC49_RS03855 c9fd6a59d64e491fa7ba32a41ecc1a88 502 Pfam PF02541 Ppx/GppA phosphatase family 22 301 2.5E-90 T 29-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 MC49_RS06735 d2d9974b9b1590de1b3e2c9a18120b30 217 SMART SM00530 8 63 1.7E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS06735 d2d9974b9b1590de1b3e2c9a18120b30 217 Gene3D G3DSA:2.10.109.10 93 211 2.0E-22 T 29-03-2018 MC49_RS06735 d2d9974b9b1590de1b3e2c9a18120b30 217 Gene3D G3DSA:1.10.260.40 2 92 8.9E-10 T 29-03-2018 MC49_RS06735 d2d9974b9b1590de1b3e2c9a18120b30 217 Pfam PF13560 Helix-turn-helix domain 10 59 2.2E-7 T 29-03-2018 MC49_RS06735 d2d9974b9b1590de1b3e2c9a18120b30 217 Pfam PF00717 Peptidase S24-like 126 200 1.4E-13 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MC49_RS06735 d2d9974b9b1590de1b3e2c9a18120b30 217 SUPERFAMILY SSF51306 119 213 2.44E-26 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MC49_RS06735 d2d9974b9b1590de1b3e2c9a18120b30 217 SUPERFAMILY SSF47413 10 59 2.95E-8 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS09600 7efdc59fae2e8bbc92e6c0311c9ff4d7 376 SUPERFAMILY SSF102114 5 376 4.84E-104 T 29-03-2018 MC49_RS09600 7efdc59fae2e8bbc92e6c0311c9ff4d7 376 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 7 368 2.9E-141 T 29-03-2018 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 MC49_RS09600 7efdc59fae2e8bbc92e6c0311c9ff4d7 376 SMART SM00729 6 223 6.0E-44 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MC49_RS09600 7efdc59fae2e8bbc92e6c0311c9ff4d7 376 Pfam PF06969 HemN C-terminal domain 304 364 1.3E-8 T 29-03-2018 IPR010723 HemN, C-terminal MC49_RS09600 7efdc59fae2e8bbc92e6c0311c9ff4d7 376 Gene3D G3DSA:3.20.20.70 3 315 5.4E-41 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS09600 7efdc59fae2e8bbc92e6c0311c9ff4d7 376 Pfam PF04055 Radical SAM superfamily 11 178 2.7E-16 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MC49_RS12465 e8b84034eb68dd3b4617529288914ab1 130 SMART SM00448 6 120 3.1E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS12465 e8b84034eb68dd3b4617529288914ab1 130 SUPERFAMILY SSF52172 5 125 2.85E-37 T 29-03-2018 IPR011006 CheY-like superfamily MC49_RS12465 e8b84034eb68dd3b4617529288914ab1 130 Gene3D G3DSA:3.40.50.2300 1 129 9.6E-38 T 29-03-2018 MC49_RS12465 e8b84034eb68dd3b4617529288914ab1 130 Pfam PF00072 Response regulator receiver domain 9 120 8.7E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS08670 fa026e3cb5042934886fe179826670d4 308 Gene3D G3DSA:2.60.200.30 165 292 6.4E-27 T 29-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 MC49_RS08670 fa026e3cb5042934886fe179826670d4 308 Gene3D G3DSA:3.40.50.10330 4 164 1.6E-11 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 MC49_RS08670 fa026e3cb5042934886fe179826670d4 308 SUPERFAMILY SSF111331 79 210 1.5E-13 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain MC49_RS10185 2dddd43eb7d23931359992d514afa4ee 678 Gene3D G3DSA:3.40.30.10 546 659 1.8E-10 T 29-03-2018 MC49_RS10185 2dddd43eb7d23931359992d514afa4ee 678 Pfam PF11412 Disulphide bond corrector protein DsbC 40 145 2.9E-17 T 29-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain MC49_RS10185 2dddd43eb7d23931359992d514afa4ee 678 Gene3D G3DSA:2.60.40.1250 26 150 4.1E-5 T 29-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain MC49_RS10185 2dddd43eb7d23931359992d514afa4ee 678 ProSitePatterns PS00194 Thioredoxin family active site. 582 600 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MC49_RS10185 2dddd43eb7d23931359992d514afa4ee 678 SUPERFAMILY SSF52833 558 671 7.34E-12 T 29-03-2018 IPR012336 Thioredoxin-like fold MC49_RS10185 2dddd43eb7d23931359992d514afa4ee 678 Pfam PF13899 Thioredoxin-like 562 649 1.5E-13 T 29-03-2018 MC49_RS10185 2dddd43eb7d23931359992d514afa4ee 678 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 285 487 8.3E-8 T 29-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 MC49_RS16960 3531c14e0012443f1a27058e1f522cb1 489 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 425 1.0E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS16960 3531c14e0012443f1a27058e1f522cb1 489 PRINTS PR00344 Bacterial sensor protein C-terminal signature 442 460 1.0E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS16960 3531c14e0012443f1a27058e1f522cb1 489 Pfam PF08918 PhoQ Sensor 8 188 1.6E-78 T 29-03-2018 IPR015014 PhoQ Sensor GO:0000160|GO:0004673|GO:0005524|GO:0016020|GO:0018106|GO:0046872 MC49_RS16960 3531c14e0012443f1a27058e1f522cb1 489 SUPERFAMILY SSF55874 341 478 2.49E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS16960 3531c14e0012443f1a27058e1f522cb1 489 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 377 479 9.2E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS16960 3531c14e0012443f1a27058e1f522cb1 489 SMART SM00387 376 482 9.0E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS16960 3531c14e0012443f1a27058e1f522cb1 489 Gene3D G3DSA:3.30.565.10 339 488 1.2E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS11855 f1590e95a64b1f814c3345685265045b 128 Gene3D G3DSA:3.90.470.20 1 128 5.3E-39 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 MC49_RS11855 f1590e95a64b1f814c3345685265045b 128 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 9 125 5.0E-32 T 29-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 MC49_RS11855 f1590e95a64b1f814c3345685265045b 128 SUPERFAMILY SSF56214 3 125 2.62E-31 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 MC49_RS11855 f1590e95a64b1f814c3345685265045b 128 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 3 126 1.8E-35 T 29-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 MC49_RS11855 f1590e95a64b1f814c3345685265045b 128 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 4 126 26.068 T 29-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 MC49_RS11855 f1590e95a64b1f814c3345685265045b 128 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 2 126 7.5E-51 T 29-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 MC49_RS11855 f1590e95a64b1f814c3345685265045b 128 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 5 121 2.1E-24 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 MC49_RS16175 23b00e81483821f80d0dba08579d7916 117 SUPERFAMILY SSF52833 4 117 4.06E-28 T 29-03-2018 IPR012336 Thioredoxin-like fold MC49_RS16175 23b00e81483821f80d0dba08579d7916 117 Gene3D G3DSA:3.40.30.10 1 117 9.1E-32 T 29-03-2018 MC49_RS16175 23b00e81483821f80d0dba08579d7916 117 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 5 117 6.9E-42 T 29-03-2018 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 MC49_RS16175 23b00e81483821f80d0dba08579d7916 117 Pfam PF03960 ArsC family 10 116 1.5E-16 T 29-03-2018 IPR006660 Arsenate reductase-like MC49_RS14370 b2eef4d156614ca2669e13eeea9578c7 318 Pfam PF07338 Protein of unknown function (DUF1471) 36 92 1.4E-19 T 29-03-2018 IPR010854 Domain of unknown function DUF1471 MC49_RS14370 b2eef4d156614ca2669e13eeea9578c7 318 Pfam PF07338 Protein of unknown function (DUF1471) 120 176 2.4E-16 T 29-03-2018 IPR010854 Domain of unknown function DUF1471 MC49_RS14370 b2eef4d156614ca2669e13eeea9578c7 318 Pfam PF07338 Protein of unknown function (DUF1471) 264 318 2.3E-18 T 29-03-2018 IPR010854 Domain of unknown function DUF1471 MC49_RS14370 b2eef4d156614ca2669e13eeea9578c7 318 SUPERFAMILY SSF159871 242 318 7.46E-17 T 29-03-2018 IPR010854 Domain of unknown function DUF1471 MC49_RS14370 b2eef4d156614ca2669e13eeea9578c7 318 SUPERFAMILY SSF159871 109 180 2.75E-14 T 29-03-2018 IPR010854 Domain of unknown function DUF1471 MC49_RS14370 b2eef4d156614ca2669e13eeea9578c7 318 SUPERFAMILY SSF159871 7 96 1.11E-20 T 29-03-2018 IPR010854 Domain of unknown function DUF1471 MC49_RS14370 b2eef4d156614ca2669e13eeea9578c7 318 Gene3D G3DSA:3.30.1660.10 115 175 4.5E-15 T 29-03-2018 IPR025543 Dodecin-like MC49_RS14370 b2eef4d156614ca2669e13eeea9578c7 318 Gene3D G3DSA:3.30.1660.10 251 318 1.0E-19 T 29-03-2018 IPR025543 Dodecin-like MC49_RS14370 b2eef4d156614ca2669e13eeea9578c7 318 Gene3D G3DSA:3.30.1660.10 24 92 4.0E-21 T 29-03-2018 IPR025543 Dodecin-like MC49_RS05980 ee0ef7c8e471dfec912fa59c1b10bdcd 124 Pfam PF07226 Protein of unknown function (DUF1422) 3 115 1.1E-50 T 29-03-2018 IPR009867 Protein of unknown function DUF1422 MC49_RS05980 ee0ef7c8e471dfec912fa59c1b10bdcd 124 ProDom PD076479 MEMBRANE INNER YIJD TRANSMEMBRANE Y0323 AAA SIMILAR A ACETYL-COENZYME VV0128 3 124 1.0E-32 T 29-03-2018 IPR009867 Protein of unknown function DUF1422 MC49_RS12200 d2b7fef09278e9ae44661685bd335a22 205 PIRSF PIRSF006170 1 205 5.6E-50 T 29-03-2018 IPR026039 Uncharacterised protein family UPF0070 MC49_RS12200 d2b7fef09278e9ae44661685bd335a22 205 Gene3D G3DSA:1.25.20.10 24 191 1.2E-5 T 29-03-2018 MC49_RS12200 d2b7fef09278e9ae44661685bd335a22 205 Pfam PF09976 Tetratricopeptide repeat-like domain 15 204 6.8E-49 T 29-03-2018 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038|Reactome: R-HSA-381426|Reactome: R-HSA-6798695|Reactome: R-HSA-8957275 MC49_RS08330 1838c6b586e580776c20cf26f8e6567f 432 Gene3D G3DSA:1.10.3860.10 1 408 5.0E-111 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MC49_RS08330 1838c6b586e580776c20cf26f8e6567f 432 SUPERFAMILY SSF118215 6 403 1.96E-108 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MC49_RS08330 1838c6b586e580776c20cf26f8e6567f 432 Pfam PF00375 Sodium:dicarboxylate symporter family 6 402 2.0E-104 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MC49_RS08330 1838c6b586e580776c20cf26f8e6567f 432 PRINTS PR00173 Glutamate-aspartate symporter signature 50 70 1.0E-40 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MC49_RS08330 1838c6b586e580776c20cf26f8e6567f 432 PRINTS PR00173 Glutamate-aspartate symporter signature 294 320 1.0E-40 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MC49_RS08330 1838c6b586e580776c20cf26f8e6567f 432 PRINTS PR00173 Glutamate-aspartate symporter signature 147 169 1.0E-40 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MC49_RS08330 1838c6b586e580776c20cf26f8e6567f 432 PRINTS PR00173 Glutamate-aspartate symporter signature 80 105 1.0E-40 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MC49_RS08330 1838c6b586e580776c20cf26f8e6567f 432 PRINTS PR00173 Glutamate-aspartate symporter signature 356 376 1.0E-40 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MC49_RS08330 1838c6b586e580776c20cf26f8e6567f 432 PRINTS PR00173 Glutamate-aspartate symporter signature 4 24 1.0E-40 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MC49_RS08330 1838c6b586e580776c20cf26f8e6567f 432 PRINTS PR00173 Glutamate-aspartate symporter signature 329 348 1.0E-40 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MC49_RS08330 1838c6b586e580776c20cf26f8e6567f 432 PRINTS PR00173 Glutamate-aspartate symporter signature 194 213 1.0E-40 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MC49_RS04370 0b63237d71db7642051ffbc97333b20e 239 Pfam PF00072 Response regulator receiver domain 7 117 5.9E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS04370 0b63237d71db7642051ffbc97333b20e 239 SMART SM00862 156 232 3.3E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MC49_RS04370 0b63237d71db7642051ffbc97333b20e 239 Gene3D G3DSA:3.40.50.2300 2 125 1.4E-39 T 29-03-2018 MC49_RS04370 0b63237d71db7642051ffbc97333b20e 239 SUPERFAMILY SSF52172 3 126 1.11E-42 T 29-03-2018 IPR011006 CheY-like superfamily MC49_RS04370 0b63237d71db7642051ffbc97333b20e 239 Gene3D G3DSA:1.10.10.10 126 239 3.4E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS04370 0b63237d71db7642051ffbc97333b20e 239 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 232 4.1E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MC49_RS04370 0b63237d71db7642051ffbc97333b20e 239 SMART SM00448 5 116 5.5E-46 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS04370 0b63237d71db7642051ffbc97333b20e 239 SUPERFAMILY SSF46894 132 234 1.42E-26 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MC49_RS06375 e6a63d155eb50c8e25ff724f53aff984 124 SUPERFAMILY SSF50249 3 123 2.57E-51 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS06375 e6a63d155eb50c8e25ff724f53aff984 124 Gene3D G3DSA:2.40.50.140 1 124 3.7E-63 T 29-03-2018 MC49_RS06375 e6a63d155eb50c8e25ff724f53aff984 124 Pfam PF00164 Ribosomal protein S12/S23 12 123 2.1E-42 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS06375 e6a63d155eb50c8e25ff724f53aff984 124 PIRSF PIRSF002133 1 124 2.0E-53 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS06375 e6a63d155eb50c8e25ff724f53aff984 124 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 124 2.5E-70 T 29-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS06375 e6a63d155eb50c8e25ff724f53aff984 124 PRINTS PR01034 Ribosomal protein S12 signature 110 122 8.6E-60 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS06375 e6a63d155eb50c8e25ff724f53aff984 124 PRINTS PR01034 Ribosomal protein S12 signature 94 110 8.6E-60 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS06375 e6a63d155eb50c8e25ff724f53aff984 124 PRINTS PR01034 Ribosomal protein S12 signature 27 42 8.6E-60 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS06375 e6a63d155eb50c8e25ff724f53aff984 124 PRINTS PR01034 Ribosomal protein S12 signature 58 77 8.6E-60 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS06375 e6a63d155eb50c8e25ff724f53aff984 124 PRINTS PR01034 Ribosomal protein S12 signature 77 94 8.6E-60 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS06375 e6a63d155eb50c8e25ff724f53aff984 124 PRINTS PR01034 Ribosomal protein S12 signature 42 57 8.6E-60 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS06375 e6a63d155eb50c8e25ff724f53aff984 124 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 38.564 T 29-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS06375 e6a63d155eb50c8e25ff724f53aff984 124 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS10920 e2be1cffe12de62145298c94f087a628 206 Gene3D G3DSA:1.20.1050.10 92 204 4.4E-28 T 29-03-2018 MC49_RS10920 e2be1cffe12de62145298c94f087a628 206 Gene3D G3DSA:3.40.30.10 1 91 2.5E-25 T 29-03-2018 MC49_RS10920 e2be1cffe12de62145298c94f087a628 206 SUPERFAMILY SSF47616 72 202 4.04E-33 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like MC49_RS10920 e2be1cffe12de62145298c94f087a628 206 Pfam PF13417 Glutathione S-transferase, N-terminal domain 9 79 3.6E-13 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MC49_RS10920 e2be1cffe12de62145298c94f087a628 206 SUPERFAMILY SSF52833 1 84 8.8E-23 T 29-03-2018 IPR012336 Thioredoxin-like fold MC49_RS10920 e2be1cffe12de62145298c94f087a628 206 Pfam PF00043 Glutathione S-transferase, C-terminal domain 115 195 4.1E-11 T 29-03-2018 IPR004046 Glutathione S-transferase, C-terminal MC49_RS03260 cb222a52d451c934caacdf71d6a681da 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 7.6E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS03260 cb222a52d451c934caacdf71d6a681da 195 SUPERFAMILY SSF46689 4 84 1.39E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS03260 cb222a52d451c934caacdf71d6a681da 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 2.9E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS03260 cb222a52d451c934caacdf71d6a681da 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 2.9E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS03260 cb222a52d451c934caacdf71d6a681da 195 Gene3D G3DSA:1.10.357.10 1 195 3.1E-33 T 29-03-2018 MC49_RS14990 d4ae3eeafca3ce128288a1dc641a3651 391 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 3 385 6.6E-112 T 29-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 MC49_RS14990 d4ae3eeafca3ce128288a1dc641a3651 391 Gene3D G3DSA:2.60.120.10 5 160 1.3E-52 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MC49_RS14990 d4ae3eeafca3ce128288a1dc641a3651 391 Pfam PF01238 Phosphomannose isomerase type I 1 355 1.8E-96 T 29-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 MC49_RS14990 d4ae3eeafca3ce128288a1dc641a3651 391 SUPERFAMILY SSF51182 1 371 1.33E-97 T 29-03-2018 IPR011051 RmlC-like cupin domain MC49_RS14990 d4ae3eeafca3ce128288a1dc641a3651 391 PRINTS PR00714 Phosphomannose isomerase type I signature 255 274 1.3E-67 T 29-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 MC49_RS14990 d4ae3eeafca3ce128288a1dc641a3651 391 PRINTS PR00714 Phosphomannose isomerase type I signature 126 149 1.3E-67 T 29-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 MC49_RS14990 d4ae3eeafca3ce128288a1dc641a3651 391 PRINTS PR00714 Phosphomannose isomerase type I signature 4 22 1.3E-67 T 29-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 MC49_RS14990 d4ae3eeafca3ce128288a1dc641a3651 391 PRINTS PR00714 Phosphomannose isomerase type I signature 236 255 1.3E-67 T 29-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 MC49_RS14990 d4ae3eeafca3ce128288a1dc641a3651 391 PRINTS PR00714 Phosphomannose isomerase type I signature 220 235 1.3E-67 T 29-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 MC49_RS14990 d4ae3eeafca3ce128288a1dc641a3651 391 PRINTS PR00714 Phosphomannose isomerase type I signature 32 47 1.3E-67 T 29-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 MC49_RS14990 d4ae3eeafca3ce128288a1dc641a3651 391 PRINTS PR00714 Phosphomannose isomerase type I signature 81 102 1.3E-67 T 29-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 MC49_RS14990 d4ae3eeafca3ce128288a1dc641a3651 391 PRINTS PR00714 Phosphomannose isomerase type I signature 274 293 1.3E-67 T 29-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 MC49_RS14990 d4ae3eeafca3ce128288a1dc641a3651 391 Gene3D G3DSA:2.60.120.10 294 391 5.4E-15 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MC49_RS14990 d4ae3eeafca3ce128288a1dc641a3651 391 Gene3D G3DSA:1.10.441.10 161 262 3.3E-28 T 29-03-2018 MC49_RS14990 d4ae3eeafca3ce128288a1dc641a3651 391 ProSitePatterns PS00965 Phosphomannose isomerase type I signature 1. 126 134 - T 29-03-2018 IPR018050 Phosphomannose isomerase, type I, conserved site GO:0004476 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 MC49_RS14990 d4ae3eeafca3ce128288a1dc641a3651 391 PIRSF PIRSF001480 1 391 5.5E-106 T 29-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 MC49_RS18145 d4a2b1f2037d8ff3ae653dc7962d9b98 679 Pfam PF07715 TonB-dependent Receptor Plug Domain 41 150 1.2E-26 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MC49_RS18145 d4a2b1f2037d8ff3ae653dc7962d9b98 679 Gene3D G3DSA:2.40.170.20 161 679 5.6E-82 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MC49_RS18145 d4a2b1f2037d8ff3ae653dc7962d9b98 679 SUPERFAMILY SSF56935 28 679 3.66E-125 T 29-03-2018 MC49_RS18145 d4a2b1f2037d8ff3ae653dc7962d9b98 679 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 35 - T 29-03-2018 IPR010916 TonB box, conserved site MC49_RS18145 d4a2b1f2037d8ff3ae653dc7962d9b98 679 Pfam PF00593 TonB dependent receptor 269 677 2.2E-59 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MC49_RS18145 d4a2b1f2037d8ff3ae653dc7962d9b98 679 Gene3D G3DSA:2.170.130.10 18 157 1.8E-34 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MC49_RS11425 7f492cfa35d8d473ea0fa959bf9253f1 186 SUPERFAMILY SSF49401 33 186 1.34E-38 T 29-03-2018 IPR008966 Adhesion domain MC49_RS11425 7f492cfa35d8d473ea0fa959bf9253f1 186 Pfam PF00419 Fimbrial protein 34 186 2.5E-22 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS11425 7f492cfa35d8d473ea0fa959bf9253f1 186 Gene3D G3DSA:2.60.40.1090 32 186 1.5E-37 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS09435 696bf76cfc17998a072ea5a2c05a0a25 293 SUPERFAMILY SSF46785 5 87 5.73E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS09435 696bf76cfc17998a072ea5a2c05a0a25 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 1.7E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS09435 696bf76cfc17998a072ea5a2c05a0a25 293 Gene3D G3DSA:1.10.10.10 3 93 3.4E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS10035 2f51b9686592bc41b03f2dc67ca04c85 401 Gene3D G3DSA:3.40.50.300 2 270 1.2E-74 T 29-03-2018 MC49_RS10035 2f51b9686592bc41b03f2dc67ca04c85 401 Pfam PF00571 CBS domain 345 393 4.8E-4 T 29-03-2018 IPR000644 CBS domain MC49_RS10035 2f51b9686592bc41b03f2dc67ca04c85 401 SUPERFAMILY SSF54631 276 398 3.54E-12 T 29-03-2018 MC49_RS10035 2f51b9686592bc41b03f2dc67ca04c85 401 SUPERFAMILY SSF52540 40 271 9.04E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS10035 2f51b9686592bc41b03f2dc67ca04c85 401 Pfam PF00005 ABC transporter 45 192 7.9E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS10035 2f51b9686592bc41b03f2dc67ca04c85 401 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 36 394 8.4E-168 T 29-03-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 MC49_RS10035 2f51b9686592bc41b03f2dc67ca04c85 401 SMART SM00382 53 242 1.8E-19 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS10035 2f51b9686592bc41b03f2dc67ca04c85 401 Gene3D G3DSA:3.10.580.10 271 401 4.1E-12 T 29-03-2018 MC49_RS10035 2f51b9686592bc41b03f2dc67ca04c85 401 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS08890 1729f4efc9a90d6551d690147d594bc2 56 TIGRFAM TIGR02616 tnaC_leader: tryptophanase leader peptide 36 55 3.0E-10 T 29-03-2018 IPR012620 Tryptophanese operon leader peptide GO:0031554|GO:0031556 MC49_RS06145 96817ce966357ffb37ef0b1ac48b61a0 338 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 242 326 1.2E-24 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MC49_RS06145 96817ce966357ffb37ef0b1ac48b61a0 338 SMART SM00382 49 241 1.9E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS06145 96817ce966357ffb37ef0b1ac48b61a0 338 Gene3D G3DSA:3.40.50.300 11 337 1.2E-77 T 29-03-2018 MC49_RS06145 96817ce966357ffb37ef0b1ac48b61a0 338 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 243 308 1.4E-19 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MC49_RS06145 96817ce966357ffb37ef0b1ac48b61a0 338 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS06145 96817ce966357ffb37ef0b1ac48b61a0 338 SUPERFAMILY SSF52540 15 263 4.5E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS06145 96817ce966357ffb37ef0b1ac48b61a0 338 Pfam PF00005 ABC transporter 40 191 2.5E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS16275 0e1d6a1c8c71e573ed4c684a19c74cbc 140 Pfam PF07681 DoxX 16 94 2.9E-18 T 29-03-2018 IPR032808 DoxX family MC49_RS15405 0a04a2e385f8591e037b88b3c6259cd2 183 SUPERFAMILY SSF55469 1 181 7.98E-40 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MC49_RS15405 0a04a2e385f8591e037b88b3c6259cd2 183 Pfam PF00881 Nitroreductase family 8 161 3.7E-21 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MC49_RS15405 0a04a2e385f8591e037b88b3c6259cd2 183 PIRSF PIRSF000232 1 182 2.0E-64 T 29-03-2018 IPR026021 Putative NAD(P)H nitroreductase YdjA-like MC49_RS15405 0a04a2e385f8591e037b88b3c6259cd2 183 Gene3D G3DSA:3.40.109.10 1 183 2.5E-31 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MC49_RS12215 4a7335b673e8162acdb15c0a774804ce 366 SUPERFAMILY SSF55486 103 364 8.79E-57 T 29-03-2018 MC49_RS12215 4a7335b673e8162acdb15c0a774804ce 366 Gene3D G3DSA:1.10.390.10 195 365 1.5E-44 T 29-03-2018 MC49_RS12215 4a7335b673e8162acdb15c0a774804ce 366 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 194 363 3.1E-37 T 29-03-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 MC49_RS12215 4a7335b673e8162acdb15c0a774804ce 366 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 202 213 1.7E-13 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 MC49_RS12215 4a7335b673e8162acdb15c0a774804ce 366 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 141 161 1.7E-13 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 MC49_RS12215 4a7335b673e8162acdb15c0a774804ce 366 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 287 303 1.7E-13 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 MC49_RS12215 4a7335b673e8162acdb15c0a774804ce 366 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 112 189 4.4E-17 T 29-03-2018 IPR013856 Peptidase M4 domain GO:0004222 MC49_RS12215 4a7335b673e8162acdb15c0a774804ce 366 Gene3D G3DSA:3.10.170.10 2 193 1.5E-29 T 29-03-2018 MC49_RS17995 3a7d035bca286efc0908adeec86b7576 73 Pfam PF12843 Putative quorum-sensing-regulated virulence factor 3 68 8.2E-29 T 29-03-2018 IPR024530 Putative quorum-sensing-regulated virulence factor MC49_RS17995 3a7d035bca286efc0908adeec86b7576 73 ProDom PD056452 UNCHARACTERIZED BACTERIA SIMILAR YPEB CYTOPLASMIC VCA0163 PRODUCT STM2426 GENE YPO2988 14 70 6.0E-21 T 29-03-2018 IPR024530 Putative quorum-sensing-regulated virulence factor MC49_RS04470 020282f23133694d13264b815b3a4a20 500 Pfam PF08946 Osmosensory transporter coiled coil 455 500 6.9E-23 T 29-03-2018 IPR015041 Osmosensory transporter coiled coil MC49_RS04470 020282f23133694d13264b815b3a4a20 500 Gene3D G3DSA:1.20.1250.20 24 239 4.4E-23 T 29-03-2018 MC49_RS04470 020282f23133694d13264b815b3a4a20 500 TIGRFAM TIGR00883 2A0106: MFS transporter, metabolite:H+ symporter (MHS) family protein 34 432 7.4E-140 T 29-03-2018 IPR004736 Citrate-proton symport GO:0005215|GO:0006810|GO:0016021 MC49_RS04470 020282f23133694d13264b815b3a4a20 500 Pfam PF00083 Sugar (and other) transporter 29 448 1.1E-58 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 MC49_RS04470 020282f23133694d13264b815b3a4a20 500 SUPERFAMILY SSF103661 466 498 2.22E-10 T 29-03-2018 IPR015041 Osmosensory transporter coiled coil MC49_RS04470 020282f23133694d13264b815b3a4a20 500 ProSitePatterns PS00216 Sugar transport proteins signature 1. 316 333 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MC49_RS04470 020282f23133694d13264b815b3a4a20 500 SUPERFAMILY SSF103473 25 445 1.96E-68 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS04470 020282f23133694d13264b815b3a4a20 500 Gene3D G3DSA:1.20.1250.20 240 490 1.2E-25 T 29-03-2018 MC49_RS17650 291415669ad776b8bd69cddd97e6ecdb 426 Pfam PF09979 Uncharacterized protein conserved in bacteria (DUF2213) 4 170 1.2E-50 T 29-03-2018 IPR016913 Uncharacterised conserved protein UCP029215 MC49_RS17650 291415669ad776b8bd69cddd97e6ecdb 426 Gene3D G3DSA:1.10.287.620 203 338 2.3E-4 T 29-03-2018 MC49_RS13990 59d0ee02db44ebb73c887cf494850e39 194 SUPERFAMILY SSF55729 13 185 1.24E-39 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS13990 59d0ee02db44ebb73c887cf494850e39 194 Gene3D G3DSA:3.40.630.30 9 192 5.4E-26 T 29-03-2018 MC49_RS13990 59d0ee02db44ebb73c887cf494850e39 194 Pfam PF13302 Acetyltransferase (GNAT) domain 17 162 3.5E-15 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MC49_RS06455 bda83a0da22701511c9967bdad6bfab2 375 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 260 363 1.7E-22 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MC49_RS06455 bda83a0da22701511c9967bdad6bfab2 375 Gene3D G3DSA:3.20.20.70 25 374 9.6E-49 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS06455 bda83a0da22701511c9967bdad6bfab2 375 Pfam PF04055 Radical SAM superfamily 84 221 4.1E-7 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MC49_RS06455 bda83a0da22701511c9967bdad6bfab2 375 TIGRFAM TIGR02351 thiH: thiazole biosynthesis protein ThiH 5 371 4.5E-164 T 29-03-2018 IPR012726 Thiazole biosynthesis ThiH GO:0005506|GO:0009228|GO:0051539 KEGG: 00730+4.1.99.19|MetaCyc: PWY-6892 MC49_RS06455 bda83a0da22701511c9967bdad6bfab2 375 SUPERFAMILY SSF102114 39 365 6.02E-54 T 29-03-2018 MC49_RS06455 bda83a0da22701511c9967bdad6bfab2 375 SMART SM00876 260 364 2.1E-33 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MC49_RS09300 099d2da725a86bc41d9934afdcc0d6c7 387 Gene3D G3DSA:2.60.60.30 18 158 2.1E-29 T 29-03-2018 MC49_RS09300 099d2da725a86bc41d9934afdcc0d6c7 387 Gene3D G3DSA:2.60.60.30 202 372 3.0E-26 T 29-03-2018 MC49_RS09300 099d2da725a86bc41d9934afdcc0d6c7 387 PIRSF PIRSF037118 1 387 3.2E-164 T 29-03-2018 IPR017115 Tellurite resistance, TerA MC49_RS09300 099d2da725a86bc41d9934afdcc0d6c7 387 Pfam PF02342 TerD domain 26 159 2.8E-26 T 29-03-2018 IPR003325 TerD domain GO:0006950 MC49_RS07000 65c2e8679eefb7c7cfbbaba5e2fe520c 88 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 38 68 2.8E-13 T 29-03-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 MC49_RS07000 65c2e8679eefb7c7cfbbaba5e2fe520c 88 SUPERFAMILY SSF57716 38 72 1.43E-8 T 29-03-2018 MC49_RS07000 65c2e8679eefb7c7cfbbaba5e2fe520c 88 TIGRFAM TIGR02419 C4_traR_proteo: phage/conjugal plasmid C-4 type zinc finger protein, TraR family 12 66 5.5E-18 T 29-03-2018 IPR012783 Zinc finger, C4 DksA/TraR-type MC49_RS07000 65c2e8679eefb7c7cfbbaba5e2fe520c 88 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 39 63 - T 29-03-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site MC49_RS07000 65c2e8679eefb7c7cfbbaba5e2fe520c 88 PRINTS PR00618 DksA/TraR zinc finger signature 51 63 4.1E-6 T 29-03-2018 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria MC49_RS07000 65c2e8679eefb7c7cfbbaba5e2fe520c 88 PRINTS PR00618 DksA/TraR zinc finger signature 39 50 4.1E-6 T 29-03-2018 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria MC49_RS00160 cef71d45a0c011ada16786f3d76bed2a 336 Pfam PF10546 P63C domain 204 296 2.4E-24 T 29-03-2018 IPR018874 Bacteriophage Mx8, p63, C-terminal MC49_RS09175 bb782b225a20ad6788dc0c4a205cefa5 460 Pfam PF01938 TRAM domain 24 82 1.2E-9 T 29-03-2018 IPR002792 TRAM domain MC49_RS09175 bb782b225a20ad6788dc0c4a205cefa5 460 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 39 447 8.0E-126 T 29-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 MC49_RS09175 bb782b225a20ad6788dc0c4a205cefa5 460 Gene3D G3DSA:2.40.50.140 15 97 2.6E-24 T 29-03-2018 MC49_RS09175 bb782b225a20ad6788dc0c4a205cefa5 460 SUPERFAMILY SSF53335 91 454 2.29E-78 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS09175 bb782b225a20ad6788dc0c4a205cefa5 460 Gene3D G3DSA:3.40.50.150 98 453 6.1E-52 T 29-03-2018 MC49_RS09175 bb782b225a20ad6788dc0c4a205cefa5 460 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 437 447 - T 29-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site MC49_RS09175 bb782b225a20ad6788dc0c4a205cefa5 460 SUPERFAMILY SSF50249 22 83 4.74E-12 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS09175 bb782b225a20ad6788dc0c4a205cefa5 460 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 386 416 - T 29-03-2018 IPR030390 RNA methyltransferase TrmA, active site MC49_RS09175 bb782b225a20ad6788dc0c4a205cefa5 460 Hamap MF_01010 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD [rlmD]. 33 455 60.113 T 29-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 MC49_RS09175 bb782b225a20ad6788dc0c4a205cefa5 460 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 275 454 8.2E-22 T 29-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 MC49_RS02260 737aa60409e505bba8e5c2f59bd7e9f3 307 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 36 264 1.1E-33 T 29-03-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system MC49_RS15540 70854c85906968c56e38977fa718d9c7 125 Pfam PF01381 Helix-turn-helix 28 81 1.2E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS15540 70854c85906968c56e38977fa718d9c7 125 Gene3D G3DSA:1.10.3100.10 18 125 1.7E-18 T 29-03-2018 IPR027910 YdiL-like domain MC49_RS15540 70854c85906968c56e38977fa718d9c7 125 SUPERFAMILY SSF47413 18 84 3.92E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS15540 70854c85906968c56e38977fa718d9c7 125 SMART SM00530 27 82 3.3E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS16240 34e3f89c3948a80c175add28e3248e30 210 Gene3D G3DSA:3.40.50.170 1 198 8.9E-71 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MC49_RS16240 34e3f89c3948a80c175add28e3248e30 210 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 135 158 - T 29-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MC49_RS16240 34e3f89c3948a80c175add28e3248e30 210 Pfam PF00551 Formyl transferase 3 183 4.5E-67 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MC49_RS16240 34e3f89c3948a80c175add28e3248e30 210 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 4 189 32.509 T 29-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 MC49_RS16240 34e3f89c3948a80c175add28e3248e30 210 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 3 191 2.7E-80 T 29-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 MC49_RS16240 34e3f89c3948a80c175add28e3248e30 210 SUPERFAMILY SSF53328 3 206 2.49E-67 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MC49_RS10660 daa8f94cf20c3dc4a6ca3114f5d4fb5d 228 Pfam PF09209 Domain of unknown function (DUF1956) 118 222 6.3E-25 T 29-03-2018 IPR015292 Transcription regulator YbiH, C-terminal MC49_RS10660 daa8f94cf20c3dc4a6ca3114f5d4fb5d 228 SUPERFAMILY SSF48498 104 223 1.47E-24 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MC49_RS10660 daa8f94cf20c3dc4a6ca3114f5d4fb5d 228 SUPERFAMILY SSF46689 7 83 1.13E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS10660 daa8f94cf20c3dc4a6ca3114f5d4fb5d 228 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 4.5E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS10660 daa8f94cf20c3dc4a6ca3114f5d4fb5d 228 Gene3D G3DSA:1.10.357.10 56 228 1.4E-28 T 29-03-2018 MC49_RS10660 daa8f94cf20c3dc4a6ca3114f5d4fb5d 228 Gene3D G3DSA:1.10.10.60 12 55 2.8E-15 T 29-03-2018 MC49_RS09780 4b9e4382a0b95303710821aa7df4441f 367 Hamap MF_00456 Glutamate 5-kinase [proB]. 5 263 36.573 T 29-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MC49_RS09780 4b9e4382a0b95303710821aa7df4441f 367 SUPERFAMILY SSF53633 6 256 7.59E-65 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MC49_RS09780 4b9e4382a0b95303710821aa7df4441f 367 SUPERFAMILY SSF88697 276 366 3.54E-23 T 29-03-2018 IPR015947 PUA-like domain MC49_RS09780 4b9e4382a0b95303710821aa7df4441f 367 Gene3D G3DSA:2.30.130.10 274 366 5.4E-29 T 29-03-2018 IPR002478 PUA domain GO:0003723 MC49_RS09780 4b9e4382a0b95303710821aa7df4441f 367 Pfam PF00696 Amino acid kinase family 6 234 1.4E-44 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MC49_RS09780 4b9e4382a0b95303710821aa7df4441f 367 Gene3D G3DSA:3.40.1160.10 1 265 5.0E-59 T 29-03-2018 MC49_RS09780 4b9e4382a0b95303710821aa7df4441f 367 PIRSF PIRSF000729 1 367 9.5E-142 T 29-03-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 MC49_RS09780 4b9e4382a0b95303710821aa7df4441f 367 ProSitePatterns PS00902 Glutamate 5-kinase signature. 207 224 - T 29-03-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MC49_RS09780 4b9e4382a0b95303710821aa7df4441f 367 SMART SM00359 276 359 1.1E-21 T 29-03-2018 IPR002478 PUA domain GO:0003723 MC49_RS09780 4b9e4382a0b95303710821aa7df4441f 367 Pfam PF01472 PUA domain 276 350 5.3E-21 T 29-03-2018 IPR002478 PUA domain GO:0003723 MC49_RS09780 4b9e4382a0b95303710821aa7df4441f 367 PRINTS PR00474 Glutamate 5-kinase family signature 76 104 2.5E-57 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MC49_RS09780 4b9e4382a0b95303710821aa7df4441f 367 PRINTS PR00474 Glutamate 5-kinase family signature 116 137 2.5E-57 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MC49_RS09780 4b9e4382a0b95303710821aa7df4441f 367 PRINTS PR00474 Glutamate 5-kinase family signature 148 175 2.5E-57 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MC49_RS09780 4b9e4382a0b95303710821aa7df4441f 367 PRINTS PR00474 Glutamate 5-kinase family signature 209 229 2.5E-57 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MC49_RS09780 4b9e4382a0b95303710821aa7df4441f 367 PRINTS PR00474 Glutamate 5-kinase family signature 42 56 2.5E-57 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MC49_RS09780 4b9e4382a0b95303710821aa7df4441f 367 TIGRFAM TIGR01027 proB: glutamate 5-kinase 5 365 1.1E-151 T 29-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MC49_RS00780 b14c1ba16873666cdd47468252990b0a 319 Gene3D G3DSA:2.60.40.420 113 280 1.6E-53 T 29-03-2018 IPR008972 Cupredoxin MC49_RS00780 b14c1ba16873666cdd47468252990b0a 319 Pfam PF06481 COX Aromatic Rich Motif 238 282 4.0E-18 T 29-03-2018 IPR010514 COX aromatic rich motif GO:0008827|GO:0016021|GO:0022900|GO:0055114 MC49_RS00780 b14c1ba16873666cdd47468252990b0a 319 TIGRFAM TIGR01433 CyoA: ubiquinol oxidase, subunit II 14 238 1.9E-116 T 29-03-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 MC49_RS00780 b14c1ba16873666cdd47468252990b0a 319 Gene3D G3DSA:1.10.287.90 28 112 3.3E-17 T 29-03-2018 MC49_RS00780 b14c1ba16873666cdd47468252990b0a 319 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 148 219 4.3E-6 T 29-03-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MC49_RS00780 b14c1ba16873666cdd47468252990b0a 319 SUPERFAMILY SSF49503 121 278 2.92E-52 T 29-03-2018 IPR008972 Cupredoxin MC49_RS00780 b14c1ba16873666cdd47468252990b0a 319 SUPERFAMILY SSF81464 19 116 1.26E-21 T 29-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MC49_RS00780 b14c1ba16873666cdd47468252990b0a 319 PIRSF PIRSF000292 1 312 4.0E-133 T 29-03-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 MC49_RS01640 d04ee4bb24f68fe4d4e1bf23ff3583a3 155 SUPERFAMILY SSF53933 50 153 4.25E-36 T 29-03-2018 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 MC49_RS01640 d04ee4bb24f68fe4d4e1bf23ff3583a3 155 PRINTS PR00117 Barnase signature 113 132 3.6E-28 T 29-03-2018 IPR001887 Barnase GO:0003723|GO:0004521 MC49_RS01640 d04ee4bb24f68fe4d4e1bf23ff3583a3 155 PRINTS PR00117 Barnase signature 135 153 3.6E-28 T 29-03-2018 IPR001887 Barnase GO:0003723|GO:0004521 MC49_RS01640 d04ee4bb24f68fe4d4e1bf23ff3583a3 155 PRINTS PR00117 Barnase signature 92 110 3.6E-28 T 29-03-2018 IPR001887 Barnase GO:0003723|GO:0004521 MC49_RS01640 d04ee4bb24f68fe4d4e1bf23ff3583a3 155 PRINTS PR00117 Barnase signature 72 89 3.6E-28 T 29-03-2018 IPR001887 Barnase GO:0003723|GO:0004521 MC49_RS01640 d04ee4bb24f68fe4d4e1bf23ff3583a3 155 PRINTS PR00117 Barnase signature 52 69 3.6E-28 T 29-03-2018 IPR001887 Barnase GO:0003723|GO:0004521 MC49_RS01640 d04ee4bb24f68fe4d4e1bf23ff3583a3 155 Gene3D G3DSA:3.10.450.30 48 155 4.4E-36 T 29-03-2018 MC49_RS01640 d04ee4bb24f68fe4d4e1bf23ff3583a3 155 PIRSF PIRSF001013 1 155 1.1E-59 T 29-03-2018 IPR001887 Barnase GO:0003723|GO:0004521 MC49_RS01640 d04ee4bb24f68fe4d4e1bf23ff3583a3 155 Pfam PF00545 ribonuclease 65 153 6.9E-25 T 29-03-2018 IPR000026 Guanine-specific ribonuclease N1/T1/U2 GO:0003723|GO:0004521 MC49_RS15400 e25b978507410c52f411444c574530c1 348 Pfam PF02769 AIR synthase related protein, C-terminal domain 169 339 5.8E-29 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MC49_RS15400 e25b978507410c52f411444c574530c1 348 SUPERFAMILY SSF55326 7 162 6.54E-42 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MC49_RS15400 e25b978507410c52f411444c574530c1 348 Pfam PF00586 AIR synthase related protein, N-terminal domain 50 157 4.1E-19 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MC49_RS15400 e25b978507410c52f411444c574530c1 348 PIRSF PIRSF036407 1 347 2.2E-118 T 29-03-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 MC49_RS15400 e25b978507410c52f411444c574530c1 348 SUPERFAMILY SSF56042 165 338 8.37E-53 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MC49_RS15400 e25b978507410c52f411444c574530c1 348 Hamap MF_00625 Selenide, water dikinase [selD]. 5 347 45.693 T 29-03-2018 IPR023061 Selenophosphate synthetase, class I GO:0004756|GO:0005524|GO:0016260 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 MC49_RS15400 e25b978507410c52f411444c574530c1 348 Gene3D G3DSA:3.30.1330.10 2 162 2.6E-36 T 29-03-2018 IPR016188 PurM-like, N-terminal domain MC49_RS15400 e25b978507410c52f411444c574530c1 348 Gene3D G3DSA:3.90.650.10 164 347 1.3E-42 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain MC49_RS15400 e25b978507410c52f411444c574530c1 348 TIGRFAM TIGR00476 selD: selenide, water dikinase 7 312 1.5E-138 T 29-03-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 MC49_RS00035 e9ae88df07227dcfd8322a3040281473 428 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 76 96 4.9E-9 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MC49_RS00035 e9ae88df07227dcfd8322a3040281473 428 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 387 402 4.9E-9 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MC49_RS00035 e9ae88df07227dcfd8322a3040281473 428 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 402 422 4.9E-9 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MC49_RS00035 e9ae88df07227dcfd8322a3040281473 428 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 271 292 4.9E-9 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MC49_RS00035 e9ae88df07227dcfd8322a3040281473 428 SUPERFAMILY SSF111369 61 153 7.85E-7 T 29-03-2018 MC49_RS00035 e9ae88df07227dcfd8322a3040281473 428 Pfam PF13437 HlyD family secretion protein 262 350 9.7E-13 T 29-03-2018 MC49_RS00035 e9ae88df07227dcfd8322a3040281473 428 ProSitePatterns PS00543 HlyD family secretion proteins signature. 387 409 - T 29-03-2018 IPR006144 Secretion protein HlyD, conserved site GO:0008565|GO:0009306|GO:0016020 MC49_RS00035 e9ae88df07227dcfd8322a3040281473 428 Gene3D G3DSA:2.40.50.100 251 381 2.7E-5 T 29-03-2018 MC49_RS00035 e9ae88df07227dcfd8322a3040281473 428 Gene3D G3DSA:2.40.50.100 60 249 5.2E-7 T 29-03-2018 MC49_RS13520 423b03e6a92a995b55e840322bcf418c 221 Gene3D G3DSA:1.10.10.10 121 221 1.3E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS13520 423b03e6a92a995b55e840322bcf418c 221 Pfam PF00072 Response regulator receiver domain 3 112 2.5E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS13520 423b03e6a92a995b55e840322bcf418c 221 Gene3D G3DSA:3.40.50.2300 1 120 4.9E-29 T 29-03-2018 MC49_RS13520 423b03e6a92a995b55e840322bcf418c 221 SMART SM00448 1 112 7.3E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS13520 423b03e6a92a995b55e840322bcf418c 221 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 216 3.1E-18 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MC49_RS13520 423b03e6a92a995b55e840322bcf418c 221 SMART SM00862 144 216 2.6E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MC49_RS13520 423b03e6a92a995b55e840322bcf418c 221 SUPERFAMILY SSF52172 2 166 6.94E-34 T 29-03-2018 IPR011006 CheY-like superfamily MC49_RS17350 d86497e32b2de638e20cd6360fef9f58 244 Gene3D G3DSA:3.40.50.150 26 242 4.3E-43 T 29-03-2018 MC49_RS17350 d86497e32b2de638e20cd6360fef9f58 244 Pfam PF08241 Methyltransferase domain 48 141 3.6E-19 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 MC49_RS17350 d86497e32b2de638e20cd6360fef9f58 244 SUPERFAMILY SSF53335 6 229 3.56E-38 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS13275 ba9228e00fee90667f4c885a1f045728 139 SUPERFAMILY SSF53955 8 138 1.07E-44 T 29-03-2018 IPR023346 Lysozyme-like domain MC49_RS13275 ba9228e00fee90667f4c885a1f045728 139 Pfam PF00959 Phage lysozyme 43 138 6.6E-21 T 29-03-2018 IPR002196 Glycoside hydrolase, family 24 GO:0003796|GO:0009253|GO:0016998 MC49_RS13275 ba9228e00fee90667f4c885a1f045728 139 Gene3D G3DSA:1.10.530.40 1 139 6.5E-43 T 29-03-2018 IPR023347 Lysozyme domain GO:0003796 MC49_RS05150 56b533cc370c1e28d908debdcf79489b 79 ProSitePatterns PS00605 ATP synthase c subunit signature. 40 61 - T 29-03-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05150 56b533cc370c1e28d908debdcf79489b 79 Pfam PF00137 ATP synthase subunit C 11 69 1.5E-9 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 MC49_RS05150 56b533cc370c1e28d908debdcf79489b 79 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 20 77 1.9E-31 T 29-03-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 MC49_RS05150 56b533cc370c1e28d908debdcf79489b 79 Gene3D G3DSA:1.20.20.10 1 79 9.1E-16 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 MC49_RS05150 56b533cc370c1e28d908debdcf79489b 79 SUPERFAMILY SSF81333 3 77 4.58E-18 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 MC49_RS05150 56b533cc370c1e28d908debdcf79489b 79 Hamap MF_01396 ATP synthase subunit c [atpH]. 10 75 14.323 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05150 56b533cc370c1e28d908debdcf79489b 79 PRINTS PR00124 ATP synthase C subunit signature 12 31 1.6E-8 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05150 56b533cc370c1e28d908debdcf79489b 79 PRINTS PR00124 ATP synthase C subunit signature 50 75 1.6E-8 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS05150 56b533cc370c1e28d908debdcf79489b 79 PRINTS PR00124 ATP synthase C subunit signature 33 48 1.6E-8 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MC49_RS13540 8487659860eeabfb530ecbabb9f9f8e7 682 Gene3D G3DSA:2.130.10.120 73 387 2.4E-52 T 29-03-2018 MC49_RS13540 8487659860eeabfb530ecbabb9f9f8e7 682 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 12 400 5.5E-89 T 29-03-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 MC49_RS13540 8487659860eeabfb530ecbabb9f9f8e7 682 SUPERFAMILY SSF50993 1 403 4.97E-84 T 29-03-2018 MC49_RS13540 8487659860eeabfb530ecbabb9f9f8e7 682 SUPERFAMILY SSF53474 413 657 1.85E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS13540 8487659860eeabfb530ecbabb9f9f8e7 682 Gene3D G3DSA:3.40.50.1820 388 666 1.1E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS13540 8487659860eeabfb530ecbabb9f9f8e7 682 Pfam PF00326 Prolyl oligopeptidase family 464 669 6.4E-65 T 29-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 MC49_RS13540 8487659860eeabfb530ecbabb9f9f8e7 682 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 532 552 2.0E-47 T 29-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MC49_RS13540 8487659860eeabfb530ecbabb9f9f8e7 682 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 502 521 2.0E-47 T 29-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MC49_RS13540 8487659860eeabfb530ecbabb9f9f8e7 682 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 590 605 2.0E-47 T 29-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MC49_RS13540 8487659860eeabfb530ecbabb9f9f8e7 682 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 474 498 2.0E-47 T 29-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MC49_RS13540 8487659860eeabfb530ecbabb9f9f8e7 682 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 608 630 2.0E-47 T 29-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MC49_RS13540 8487659860eeabfb530ecbabb9f9f8e7 682 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 448 466 2.0E-47 T 29-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MC49_RS16580 f87f4d10a613c7205b096c14bcbdbe06 715 Gene3D G3DSA:3.40.50.300 1 227 3.9E-30 T 29-03-2018 MC49_RS16580 f87f4d10a613c7205b096c14bcbdbe06 715 Pfam PF07085 DRTGG domain 231 342 3.1E-30 T 29-03-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MC49_RS16580 f87f4d10a613c7205b096c14bcbdbe06 715 SUPERFAMILY SSF52540 4 238 3.72E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS16580 f87f4d10a613c7205b096c14bcbdbe06 715 Gene3D G3DSA:3.40.50.20 396 531 0.43 T 29-03-2018 MC49_RS16580 f87f4d10a613c7205b096c14bcbdbe06 715 SUPERFAMILY SSF75138 227 351 1.7E-26 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like MC49_RS16580 f87f4d10a613c7205b096c14bcbdbe06 715 SUPERFAMILY SSF53659 391 708 5.35E-96 T 29-03-2018 MC49_RS16580 f87f4d10a613c7205b096c14bcbdbe06 715 Gene3D G3DSA:3.40.50.10750 532 680 3.2E-65 T 29-03-2018 MC49_RS16580 f87f4d10a613c7205b096c14bcbdbe06 715 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 404 704 7.3E-136 T 29-03-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MC49_RS16580 f87f4d10a613c7205b096c14bcbdbe06 715 Gene3D G3DSA:3.40.1390.20 228 364 1.2E-29 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like MC49_RS16580 f87f4d10a613c7205b096c14bcbdbe06 715 PIRSF PIRSF006107 1 712 0.0 T 29-03-2018 IPR016475 Phosphate acetyltransferase, bacteria GO:0008959 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MC49_RS16580 f87f4d10a613c7205b096c14bcbdbe06 715 Pfam PF13500 AAA domain 3 227 4.7E-39 T 29-03-2018 MC49_RS16580 f87f4d10a613c7205b096c14bcbdbe06 715 Pfam PF01515 Phosphate acetyl/butaryl transferase 389 704 1.9E-126 T 29-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MC49_RS01335 35315a57aa1c5d66931580cd6802750e 569 SUPERFAMILY SSF53383 87 472 1.72E-69 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS01335 35315a57aa1c5d66931580cd6802750e 569 SUPERFAMILY SSF53383 510 566 1.72E-69 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS01335 35315a57aa1c5d66931580cd6802750e 569 Gene3D G3DSA:3.90.1150.10 422 569 1.6E-17 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS01335 35315a57aa1c5d66931580cd6802750e 569 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 103 469 1.0E-26 T 29-03-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 MC49_RS01335 35315a57aa1c5d66931580cd6802750e 569 Gene3D G3DSA:3.40.640.10 120 421 2.7E-33 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS01110 ef8af38c101907c2bcefad637914d902 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 35 79 6.4E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS01110 ef8af38c101907c2bcefad637914d902 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 56 79 6.5E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS01110 ef8af38c101907c2bcefad637914d902 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 48 6.5E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS01110 ef8af38c101907c2bcefad637914d902 211 Gene3D G3DSA:1.10.10.60 71 199 1.8E-9 T 29-03-2018 MC49_RS01110 ef8af38c101907c2bcefad637914d902 211 SUPERFAMILY SSF48498 117 198 4.0E-5 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MC49_RS01110 ef8af38c101907c2bcefad637914d902 211 Gene3D G3DSA:1.10.10.60 2 70 2.7E-18 T 29-03-2018 MC49_RS01110 ef8af38c101907c2bcefad637914d902 211 SUPERFAMILY SSF46689 25 89 1.26E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS04510 aca239a4733c8be56223e60b0e6c4356 440 TIGRFAM TIGR00366 TIGR00366: TIGR00366 family protein 4 428 8.1E-216 T 29-03-2018 IPR006161 Conserved hypothetical protein CHP00336 MC49_RS04510 aca239a4733c8be56223e60b0e6c4356 440 Pfam PF02667 Short chain fatty acid transporter 1 440 1.1E-220 T 29-03-2018 IPR006160 Short chain fatty acid transporter AtoE MC49_RS13950 49522332c923e362b8711eb65f0e3706 573 TIGRFAM TIGR00815 sulP: sulfate permease 19 559 1.4E-128 T 29-03-2018 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 MC49_RS13950 49522332c923e362b8711eb65f0e3706 573 Pfam PF01740 STAS domain 459 559 2.0E-8 T 29-03-2018 IPR002645 STAS domain MC49_RS13950 49522332c923e362b8711eb65f0e3706 573 ProSitePatterns PS01130 SLC26A transporters signature. 58 79 - T 29-03-2018 IPR018045 Sulphate anion transporter, conserved site GO:0008271|GO:0008272 Reactome: R-HSA-427601 MC49_RS13950 49522332c923e362b8711eb65f0e3706 573 SUPERFAMILY SSF52091 459 560 1.1E-9 T 29-03-2018 IPR002645 STAS domain MC49_RS13950 49522332c923e362b8711eb65f0e3706 573 Pfam PF00916 Sulfate permease family 29 414 7.5E-79 T 29-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 MC49_RS13950 49522332c923e362b8711eb65f0e3706 573 Gene3D G3DSA:3.30.750.24 438 563 7.5E-13 T 29-03-2018 IPR002645 STAS domain MC49_RS08040 21d12f6d36f3194ab249fc264dfbde80 242 SUPERFAMILY SSF53633 7 240 5.63E-72 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MC49_RS08040 21d12f6d36f3194ab249fc264dfbde80 242 Hamap MF_01220_B Uridylate kinase [pyrH]. 7 240 43.897 T 29-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 MC49_RS08040 21d12f6d36f3194ab249fc264dfbde80 242 Pfam PF00696 Amino acid kinase family 11 219 1.8E-27 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase MC49_RS08040 21d12f6d36f3194ab249fc264dfbde80 242 Gene3D G3DSA:3.40.1160.10 2 241 1.4E-43 T 29-03-2018 MC49_RS08040 21d12f6d36f3194ab249fc264dfbde80 242 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 9 240 8.2E-104 T 29-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 MC49_RS08040 21d12f6d36f3194ab249fc264dfbde80 242 PIRSF PIRSF005650 4 242 5.2E-90 T 29-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 MC49_RS09750 69fb4bbefc637a6b41e5afa5743feb20 269 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 12 121 6.8E-13 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 MC49_RS09750 69fb4bbefc637a6b41e5afa5743feb20 269 Gene3D G3DSA:3.20.20.190 1 267 2.3E-40 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 MC49_RS09750 69fb4bbefc637a6b41e5afa5743feb20 269 SUPERFAMILY SSF51695 7 262 4.45E-41 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 MC49_RS15065 100fe48b06a7b085db74e94887d39d63 107 SUPERFAMILY SSF55159 7 103 4.97E-25 T 29-03-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 MC49_RS15065 100fe48b06a7b085db74e94887d39d63 107 Gene3D G3DSA:3.30.780.10 15 105 4.0E-20 T 29-03-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 MC49_RS15065 100fe48b06a7b085db74e94887d39d63 107 TIGRFAM TIGR01158 SUI1_rel: putative translation initiation factor SUI1 7 107 1.2E-39 T 29-03-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 MC49_RS15065 100fe48b06a7b085db74e94887d39d63 107 Pfam PF01253 Translation initiation factor SUI1 31 101 1.6E-18 T 29-03-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 MC49_RS15065 100fe48b06a7b085db74e94887d39d63 107 PIRSF PIRSF037511 1 107 4.1E-37 T 29-03-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 MC49_RS07040 7528e59b17e6231c2715bb4950fe1899 264 SUPERFAMILY SSF55166 57 210 9.42E-21 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MC49_RS07040 7528e59b17e6231c2715bb4950fe1899 264 Gene3D G3DSA:3.30.1380.10 57 211 3.0E-17 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MC49_RS07040 7528e59b17e6231c2715bb4950fe1899 264 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 128 210 9.0E-18 T 29-03-2018 MC49_RS05155 68759186cd2f75e88f7eacc564ca0e9f 156 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 10 156 1.8E-58 T 29-03-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 MC49_RS05155 68759186cd2f75e88f7eacc564ca0e9f 156 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 138 13.087 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 MC49_RS05155 68759186cd2f75e88f7eacc564ca0e9f 156 Gene3D G3DSA:1.20.5.620 62 122 4.0E-15 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain MC49_RS05155 68759186cd2f75e88f7eacc564ca0e9f 156 SUPERFAMILY SSF81573 63 121 3.27E-15 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain MC49_RS05155 68759186cd2f75e88f7eacc564ca0e9f 156 Pfam PF00430 ATP synthase B/B' CF(0) 6 137 4.7E-39 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 MC49_RS11735 a63b549c781bb00bce6cc28bb48fec27 423 Gene3D G3DSA:1.20.1250.20 219 420 6.3E-16 T 29-03-2018 MC49_RS11735 a63b549c781bb00bce6cc28bb48fec27 423 Gene3D G3DSA:1.20.1250.20 3 218 2.5E-29 T 29-03-2018 MC49_RS11735 a63b549c781bb00bce6cc28bb48fec27 423 Pfam PF07690 Major Facilitator Superfamily 18 251 5.1E-22 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS11735 a63b549c781bb00bce6cc28bb48fec27 423 SUPERFAMILY SSF103473 1 418 1.44E-62 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS02625 bd4bd9293346dd91801cbbd87aebe0ec 337 SUPERFAMILY SSF81345 5 331 3.14E-78 T 29-03-2018 IPR029022 ABC transporter, BtuC-like MC49_RS02625 bd4bd9293346dd91801cbbd87aebe0ec 337 Gene3D G3DSA:1.10.3470.10 2 337 8.6E-72 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like MC49_RS02625 bd4bd9293346dd91801cbbd87aebe0ec 337 Pfam PF01032 FecCD transport family 13 331 1.4E-87 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 MC49_RS03755 057390190c95afed5cb8cec1b0c148dc 402 Gene3D G3DSA:1.25.40.10 82 223 1.3E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MC49_RS03755 057390190c95afed5cb8cec1b0c148dc 402 Pfam PF07219 HemY protein N-terminus 26 131 7.1E-30 T 29-03-2018 IPR010817 HemY, N-terminal MC49_RS03755 057390190c95afed5cb8cec1b0c148dc 402 TIGRFAM TIGR00540 TPR_hemY_coli: heme biosynthesis-associated TPR protein 4 387 7.4E-110 T 29-03-2018 IPR005254 Heme biosynthesis-associated TPR protein GO:0016020|GO:0042168 MC49_RS03755 057390190c95afed5cb8cec1b0c148dc 402 Gene3D G3DSA:1.25.40.10 224 389 1.7E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MC49_RS03755 057390190c95afed5cb8cec1b0c148dc 402 SUPERFAMILY SSF48452 93 213 5.32E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MC49_RS03755 057390190c95afed5cb8cec1b0c148dc 402 SUPERFAMILY SSF48452 259 388 5.32E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MC49_RS15240 3b3f7b494c37720d69ab69b47ecaaf87 246 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 169 237 7.0E-19 T 29-03-2018 IPR006260 TonB, C-terminal GO:0006810 MC49_RS15240 3b3f7b494c37720d69ab69b47ecaaf87 246 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 168 237 3.6E-19 T 29-03-2018 IPR006260 TonB, C-terminal GO:0006810 MC49_RS15240 3b3f7b494c37720d69ab69b47ecaaf87 246 PRINTS PR01374 Gram-negative bacterial tonB protein signature 203 220 1.5E-30 T 29-03-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 MC49_RS15240 3b3f7b494c37720d69ab69b47ecaaf87 246 PRINTS PR01374 Gram-negative bacterial tonB protein signature 184 202 1.5E-30 T 29-03-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 MC49_RS15240 3b3f7b494c37720d69ab69b47ecaaf87 246 PRINTS PR01374 Gram-negative bacterial tonB protein signature 94 104 1.5E-30 T 29-03-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 MC49_RS15240 3b3f7b494c37720d69ab69b47ecaaf87 246 PRINTS PR01374 Gram-negative bacterial tonB protein signature 163 184 1.5E-30 T 29-03-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 MC49_RS15240 3b3f7b494c37720d69ab69b47ecaaf87 246 Gene3D G3DSA:3.30.2420.10 172 246 8.1E-18 T 29-03-2018 MC49_RS15240 3b3f7b494c37720d69ab69b47ecaaf87 246 Pfam PF16031 TonB N-terminal region 37 147 3.9E-14 T 29-03-2018 MC49_RS15240 3b3f7b494c37720d69ab69b47ecaaf87 246 SUPERFAMILY SSF74653 160 237 8.63E-21 T 29-03-2018 MC49_RS13970 e241c170eddf91d02f46fdc17e5c30d9 186 SUPERFAMILY SSF89155 2 177 4.71E-37 T 29-03-2018 IPR020945 DMSO/Nitrate reductase chaperone MC49_RS13970 e241c170eddf91d02f46fdc17e5c30d9 186 Pfam PF02613 Nitrate reductase delta subunit 41 144 2.5E-6 T 29-03-2018 IPR020945 DMSO/Nitrate reductase chaperone MC49_RS13970 e241c170eddf91d02f46fdc17e5c30d9 186 Gene3D G3DSA:1.10.3480.10 1 184 6.3E-28 T 29-03-2018 IPR020945 DMSO/Nitrate reductase chaperone MC49_RS13970 e241c170eddf91d02f46fdc17e5c30d9 186 PIRSF PIRSF004690 1 184 8.4E-56 T 29-03-2018 IPR026269 Tat proofreading chaperone DmsD-type MC49_RS18725 37dd6cbb190a78b385db97b0f3f63228 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 50 60 1.3E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS18725 37dd6cbb190a78b385db97b0f3f63228 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.3E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS18725 37dd6cbb190a78b385db97b0f3f63228 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 60 71 1.3E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS18725 37dd6cbb190a78b385db97b0f3f63228 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 24 82 8.3E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS18725 37dd6cbb190a78b385db97b0f3f63228 315 SUPERFAMILY SSF46785 19 98 1.02E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS18725 37dd6cbb190a78b385db97b0f3f63228 315 Pfam PF03466 LysR substrate binding domain 112 309 1.8E-12 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS18725 37dd6cbb190a78b385db97b0f3f63228 315 Gene3D G3DSA:3.40.190.10 105 315 4.5E-11 T 29-03-2018 MC49_RS18725 37dd6cbb190a78b385db97b0f3f63228 315 SUPERFAMILY SSF53850 105 310 8.51E-32 T 29-03-2018 MC49_RS18725 37dd6cbb190a78b385db97b0f3f63228 315 Gene3D G3DSA:1.10.10.10 17 99 3.9E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS07250 502baae4e240f0a37b2b96b75fb4dad8 551 Gene3D G3DSA:1.20.58.220 437 535 3.1E-7 T 29-03-2018 MC49_RS07250 502baae4e240f0a37b2b96b75fb4dad8 551 Pfam PF02690 Na+/Pi-cotransporter 13 147 6.9E-34 T 29-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 MC49_RS07250 502baae4e240f0a37b2b96b75fb4dad8 551 Pfam PF02690 Na+/Pi-cotransporter 158 245 2.4E-8 T 29-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 MC49_RS07250 502baae4e240f0a37b2b96b75fb4dad8 551 TIGRFAM TIGR01013 2a58: sodium-dependent inorganic phosphate (Pi) transporter 67 520 8.7E-99 T 29-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 MC49_RS07250 502baae4e240f0a37b2b96b75fb4dad8 551 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 1 306 1.3E-100 T 29-03-2018 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 MC49_RS07250 502baae4e240f0a37b2b96b75fb4dad8 551 SUPERFAMILY SSF109755 320 531 9.16E-19 T 29-03-2018 MC49_RS07250 502baae4e240f0a37b2b96b75fb4dad8 551 Gene3D G3DSA:1.20.58.220 322 435 1.5E-4 T 29-03-2018 MC49_RS00335 7c659621cd6d2ea6a75c303ca72f0da7 210 Pfam PF00717 Peptidase S24-like 118 169 8.5E-12 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MC49_RS00335 7c659621cd6d2ea6a75c303ca72f0da7 210 SMART SM00530 6 60 2.1E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS00335 7c659621cd6d2ea6a75c303ca72f0da7 210 Pfam PF01381 Helix-turn-helix 8 60 5.8E-7 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS00335 7c659621cd6d2ea6a75c303ca72f0da7 210 SUPERFAMILY SSF47413 3 63 4.56E-11 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS00335 7c659621cd6d2ea6a75c303ca72f0da7 210 Gene3D G3DSA:2.10.109.10 81 204 2.0E-17 T 29-03-2018 MC49_RS00335 7c659621cd6d2ea6a75c303ca72f0da7 210 Gene3D G3DSA:1.10.260.40 1 80 4.9E-14 T 29-03-2018 MC49_RS00335 7c659621cd6d2ea6a75c303ca72f0da7 210 SUPERFAMILY SSF51306 75 201 6.54E-21 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MC49_RS00645 9ad2cf2f843171178ddc2b24a8dcf584 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 3.5E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS00645 9ad2cf2f843171178ddc2b24a8dcf584 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 3.5E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS00645 9ad2cf2f843171178ddc2b24a8dcf584 215 Gene3D G3DSA:1.10.10.60 50 186 4.6E-11 T 29-03-2018 MC49_RS00645 9ad2cf2f843171178ddc2b24a8dcf584 215 SUPERFAMILY SSF48498 90 203 4.89E-13 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MC49_RS00645 9ad2cf2f843171178ddc2b24a8dcf584 215 Gene3D G3DSA:1.10.10.60 1 49 3.8E-21 T 29-03-2018 MC49_RS00645 9ad2cf2f843171178ddc2b24a8dcf584 215 Pfam PF08361 MAATS-type transcriptional repressor, C-terminal region 84 203 2.9E-50 T 29-03-2018 IPR013572 Transcription regulator MAATS, C-terminal GO:0003677 MC49_RS00645 9ad2cf2f843171178ddc2b24a8dcf584 215 SUPERFAMILY SSF46689 1 64 8.48E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS00645 9ad2cf2f843171178ddc2b24a8dcf584 215 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 58 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MC49_RS00645 9ad2cf2f843171178ddc2b24a8dcf584 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 3.8E-18 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS01765 2fe73b29ca4cc09cff8da21648a64414 196 Pfam PF02669 K+-transporting ATPase, c chain 5 186 1.2E-69 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 MC49_RS01765 2fe73b29ca4cc09cff8da21648a64414 196 PIRSF PIRSF001296 1 192 1.1E-74 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 MC49_RS01765 2fe73b29ca4cc09cff8da21648a64414 196 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 1 188 32.972 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 MC49_RS01765 2fe73b29ca4cc09cff8da21648a64414 196 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 2 187 7.4E-75 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 MC49_RS08575 61dd5beefe9ffb266ab7523b25e72c70 95 Pfam PF03319 Ethanolamine utilisation protein EutN/carboxysome 1 83 1.4E-30 T 29-03-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml MC49_RS08575 61dd5beefe9ffb266ab7523b25e72c70 95 Gene3D G3DSA:2.40.50.220 2 95 1.1E-32 T 29-03-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml MC49_RS08575 61dd5beefe9ffb266ab7523b25e72c70 95 ProDom PD012510 UTILIZATION ETHANOLAMINE CARBOXYSOME CCML PEPTIDE EUTN/CARBOXYSOME STRUCTURAL EUTN A B 11 83 4.0E-25 T 29-03-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml MC49_RS08575 61dd5beefe9ffb266ab7523b25e72c70 95 SUPERFAMILY SSF159133 1 94 9.42E-30 T 29-03-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml MC49_RS04035 aa942b3b7e062fa13e71478ec65e9e15 329 SUPERFAMILY SSF47789 251 325 1.27E-25 T 29-03-2018 MC49_RS04035 aa942b3b7e062fa13e71478ec65e9e15 329 SUPERFAMILY SSF55257 179 231 9.81E-30 T 29-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS04035 aa942b3b7e062fa13e71478ec65e9e15 329 SUPERFAMILY SSF55257 6 53 9.81E-30 T 29-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS04035 aa942b3b7e062fa13e71478ec65e9e15 329 SUPERFAMILY SSF56553 53 178 2.27E-42 T 29-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS04035 aa942b3b7e062fa13e71478ec65e9e15 329 SMART SM00662 23 234 1.5E-105 T 29-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS04035 aa942b3b7e062fa13e71478ec65e9e15 329 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 60 156 1.4E-23 T 29-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS04035 aa942b3b7e062fa13e71478ec65e9e15 329 Gene3D G3DSA:1.10.150.20 245 328 7.6E-29 T 29-03-2018 MC49_RS04035 aa942b3b7e062fa13e71478ec65e9e15 329 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 245 308 7.5E-24 T 29-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS04035 aa942b3b7e062fa13e71478ec65e9e15 329 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 24 316 3.2E-112 T 29-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS04035 aa942b3b7e062fa13e71478ec65e9e15 329 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 5 317 34.518 T 29-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS04035 aa942b3b7e062fa13e71478ec65e9e15 329 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 256 329 2.0E-36 T 29-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS04035 aa942b3b7e062fa13e71478ec65e9e15 329 Gene3D G3DSA:3.30.1360.10 119 231 3.5E-27 T 29-03-2018 MC49_RS04035 aa942b3b7e062fa13e71478ec65e9e15 329 Gene3D G3DSA:3.30.1360.10 4 100 2.5E-19 T 29-03-2018 MC49_RS04035 aa942b3b7e062fa13e71478ec65e9e15 329 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 29 228 3.5E-23 T 29-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS15895 ac54a58f8aa5135bc5f3da8301567791 338 SUPERFAMILY SSF82649 249 336 2.3E-24 T 29-03-2018 MC49_RS15895 ac54a58f8aa5135bc5f3da8301567791 338 Pfam PF03099 Biotin/lipoate A/B protein ligase family 52 158 2.7E-9 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 MC49_RS15895 ac54a58f8aa5135bc5f3da8301567791 338 Gene3D G3DSA:3.30.390.50 250 337 1.0E-22 T 29-03-2018 MC49_RS15895 ac54a58f8aa5135bc5f3da8301567791 338 Hamap MF_01602 Lipoate-protein ligase A [lplA]. 1 338 57.751 T 29-03-2018 IPR023741 Lipoate-protein ligase A GO:0016979|GO:0018055 KEGG: 00785+6.3.1.20 MC49_RS15895 ac54a58f8aa5135bc5f3da8301567791 338 SUPERFAMILY SSF55681 4 247 2.15E-80 T 29-03-2018 MC49_RS15895 ac54a58f8aa5135bc5f3da8301567791 338 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 250 316 1.8E-19 T 29-03-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 MC49_RS15895 ac54a58f8aa5135bc5f3da8301567791 338 TIGRFAM TIGR00545 lipoyltrans: lipoyltransferase and lipoate-protein ligase 5 326 7.6E-123 T 29-03-2018 IPR004562 Lipoyltransferase/lipoate-protein ligase GO:0009249 KEGG: 00785+6.3.1.20|Reactome: R-HSA-389661 MC49_RS15895 ac54a58f8aa5135bc5f3da8301567791 338 Gene3D G3DSA:3.30.930.10 2 249 1.2E-72 T 29-03-2018 MC49_RS13725 c752ddb8758b0d2628f7e81ba51422f3 894 Pfam PF10101 Predicted membrane protein (DUF2339) 126 880 9.0E-150 T 29-03-2018 IPR019286 Protein of unknown function DUF2339, transmembrane MC49_RS13725 c752ddb8758b0d2628f7e81ba51422f3 894 PIRSF PIRSF035905 4 581 1.7E-55 T 29-03-2018 IPR014600 Uncharacterised conserved protein UCP035905, membrane protein MC49_RS13725 c752ddb8758b0d2628f7e81ba51422f3 894 PIRSF PIRSF035905 544 890 4.4E-20 T 29-03-2018 IPR014600 Uncharacterised conserved protein UCP035905, membrane protein MC49_RS07510 c1301caf5a0fbf470d6fabe2d899342c 149 PIRSF PIRSF003174 1 149 1.1E-63 T 29-03-2018 IPR010292 Uncharacterised protein family CreA MC49_RS07510 c1301caf5a0fbf470d6fabe2d899342c 149 Pfam PF05981 CreA protein 15 147 2.1E-56 T 29-03-2018 IPR010292 Uncharacterised protein family CreA MC49_RS09935 0319c34a2d850ccd181fb41182f3d0f4 248 SUPERFAMILY SSF64438 3 242 1.76E-86 T 29-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic MC49_RS09935 0319c34a2d850ccd181fb41182f3d0f4 248 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 25 242 6.2E-69 T 29-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase MC49_RS09935 0319c34a2d850ccd181fb41182f3d0f4 248 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 21 241 7.1E-79 T 29-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase MC49_RS09935 0319c34a2d850ccd181fb41182f3d0f4 248 Gene3D G3DSA:3.60.140.10 1 246 2.6E-95 T 29-03-2018 MC49_RS05240 85a05c1f782b36e308c7491a54ed9636 383 SUPERFAMILY SSF116734 197 383 2.13E-27 T 29-03-2018 MC49_RS05240 85a05c1f782b36e308c7491a54ed9636 383 Pfam PF01420 Type I restriction modification DNA specificity domain 9 164 7.6E-21 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 MC49_RS05240 85a05c1f782b36e308c7491a54ed9636 383 Pfam PF01420 Type I restriction modification DNA specificity domain 197 364 2.5E-9 T 29-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 MC49_RS05240 85a05c1f782b36e308c7491a54ed9636 383 SUPERFAMILY SSF116734 4 189 1.8E-34 T 29-03-2018 MC49_RS05240 85a05c1f782b36e308c7491a54ed9636 383 Gene3D G3DSA:3.90.220.20 170 369 7.1E-23 T 29-03-2018 MC49_RS05240 85a05c1f782b36e308c7491a54ed9636 383 Gene3D G3DSA:3.90.220.20 1 169 1.7E-28 T 29-03-2018 MC49_RS13300 bdc0a7ad81c8fd76d652f9849e9f6389 111 Pfam PF09864 Membrane-bound lysozyme-inhibitor of c-type lysozyme 33 101 1.5E-12 T 29-03-2018 IPR018660 C-type lysozyme inhibitor MC49_RS13300 bdc0a7ad81c8fd76d652f9849e9f6389 111 SUPERFAMILY SSF141488 28 103 4.32E-12 T 29-03-2018 IPR018660 C-type lysozyme inhibitor MC49_RS09590 9cddf0cab5fc19c36ae50e2dcc79cc25 242 Pfam PF11101 Protein of unknown function (DUF2884) 24 240 3.3E-36 T 29-03-2018 IPR021307 Protein of unknown function DUF2884 MC49_RS00605 468140c21d4bcd9b20068c2f7eaff37c 205 SMART SM00493 81 166 2.6E-17 T 29-03-2018 IPR006171 TOPRIM domain MC49_RS00605 468140c21d4bcd9b20068c2f7eaff37c 205 Hamap MF_00017 Recombination protein RecR [recR]. 1 199 103.734 T 29-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 MC49_RS00605 468140c21d4bcd9b20068c2f7eaff37c 205 Pfam PF13662 Toprim domain 82 172 7.9E-23 T 29-03-2018 IPR006171 TOPRIM domain MC49_RS00605 468140c21d4bcd9b20068c2f7eaff37c 205 TIGRFAM TIGR00615 recR: recombination protein RecR 2 197 5.2E-81 T 29-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 MC49_RS00605 468140c21d4bcd9b20068c2f7eaff37c 205 ProSitePatterns PS01300 RecR protein signature. 57 78 - T 29-03-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 MC49_RS00605 468140c21d4bcd9b20068c2f7eaff37c 205 Gene3D G3DSA:3.40.1360.10 77 171 2.8E-35 T 29-03-2018 MC49_RS00605 468140c21d4bcd9b20068c2f7eaff37c 205 SUPERFAMILY SSF111304 2 199 2.48E-71 T 29-03-2018 IPR023627 Recombination protein RecR MC49_RS00605 468140c21d4bcd9b20068c2f7eaff37c 205 Pfam PF02132 RecR protein 41 77 9.0E-15 T 29-03-2018 IPR023628 Recombination protein RecR, C4-type zinc finger MC49_RS04980 165c0ccc428101deea85182207f0898b 228 SMART SM00418 17 96 9.1E-15 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MC49_RS04980 165c0ccc428101deea85182207f0898b 228 Gene3D G3DSA:1.10.10.10 90 226 0.2 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS04980 165c0ccc428101deea85182207f0898b 228 SUPERFAMILY SSF46785 12 96 1.36E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS04980 165c0ccc428101deea85182207f0898b 228 Gene3D G3DSA:1.10.10.10 5 89 1.7E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS04980 165c0ccc428101deea85182207f0898b 228 Pfam PF12840 Helix-turn-helix domain 18 75 1.5E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS16385 9b8a103a1fb9539784493f481acedd57 440 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 11 415 1.7E-124 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 MC49_RS16385 9b8a103a1fb9539784493f481acedd57 440 Pfam PF05525 Branched-chain amino acid transport protein 4 427 4.3E-134 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 MC49_RS17235 a6e42ad701e4b2b2720c5d820496a51b 415 Pfam PF03222 Tryptophan/tyrosine permease family 10 403 5.2E-146 T 29-03-2018 IPR018227 Amino acid/polyamine transporter 2 GO:0003333 MC49_RS17235 a6e42ad701e4b2b2720c5d820496a51b 415 TIGRFAM TIGR00837 araaP: aromatic amino acid transport protein 16 396 8.9E-150 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS17235 a6e42ad701e4b2b2720c5d820496a51b 415 PRINTS PR00166 Aromatic amino acid permease signature 156 176 2.6E-99 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS17235 a6e42ad701e4b2b2720c5d820496a51b 415 PRINTS PR00166 Aromatic amino acid permease signature 294 313 2.6E-99 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS17235 a6e42ad701e4b2b2720c5d820496a51b 415 PRINTS PR00166 Aromatic amino acid permease signature 46 65 2.6E-99 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS17235 a6e42ad701e4b2b2720c5d820496a51b 415 PRINTS PR00166 Aromatic amino acid permease signature 233 252 2.6E-99 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS17235 a6e42ad701e4b2b2720c5d820496a51b 415 PRINTS PR00166 Aromatic amino acid permease signature 194 216 2.6E-99 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS17235 a6e42ad701e4b2b2720c5d820496a51b 415 PRINTS PR00166 Aromatic amino acid permease signature 328 346 2.6E-99 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS17235 a6e42ad701e4b2b2720c5d820496a51b 415 PRINTS PR00166 Aromatic amino acid permease signature 19 42 2.6E-99 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS17235 a6e42ad701e4b2b2720c5d820496a51b 415 PRINTS PR00166 Aromatic amino acid permease signature 349 368 2.6E-99 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS17235 a6e42ad701e4b2b2720c5d820496a51b 415 PRINTS PR00166 Aromatic amino acid permease signature 91 111 2.6E-99 T 29-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 MC49_RS17235 a6e42ad701e4b2b2720c5d820496a51b 415 PIRSF PIRSF006060 7 306 1.3E-12 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MC49_RS17235 a6e42ad701e4b2b2720c5d820496a51b 415 PIRSF PIRSF006060 329 371 200.0 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MC49_RS08940 025f2e818ae9fdfdca275b40c8169df2 692 Gene3D G3DSA:1.10.3720.10 139 407 3.0E-35 T 29-03-2018 MC49_RS08940 025f2e818ae9fdfdca275b40c8169df2 692 Gene3D G3DSA:1.10.3720.10 425 686 5.0E-37 T 29-03-2018 MC49_RS08940 025f2e818ae9fdfdca275b40c8169df2 692 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 500 677 1.1E-12 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS08940 025f2e818ae9fdfdca275b40c8169df2 692 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 209 403 1.0E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS08940 025f2e818ae9fdfdca275b40c8169df2 692 SUPERFAMILY SSF161098 433 674 3.53E-46 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS08940 025f2e818ae9fdfdca275b40c8169df2 692 SUPERFAMILY SSF161098 145 405 1.44E-42 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS11630 f0cce0eb97854b8ce44fb0be7c700f13 468 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 21 426 4.2E-24 T 29-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 MC49_RS06475 a61818d5c122608f8222f0747082675a 221 SUPERFAMILY SSF51391 5 207 1.83E-64 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MC49_RS06475 a61818d5c122608f8222f0747082675a 221 Gene3D G3DSA:3.20.20.70 9 207 3.1E-43 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS06475 a61818d5c122608f8222f0747082675a 221 Pfam PF02581 Thiamine monophosphate synthase 23 191 2.2E-56 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MC49_RS06475 a61818d5c122608f8222f0747082675a 221 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 23 204 8.1E-56 T 29-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MC49_RS06475 a61818d5c122608f8222f0747082675a 221 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 12 209 20.381 T 29-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MC49_RS11090 2994ef1c1b1f7c2fffe6c162b1285376 393 Gene3D G3DSA:3.90.1760.10 79 223 9.7E-42 T 29-03-2018 IPR005165 Anthrax toxin, edema factor, central GO:0005576|GO:0008294|GO:0009405 KEGG: 00230+4.6.1.1 MC49_RS11090 2994ef1c1b1f7c2fffe6c162b1285376 393 Pfam PF03497 Anthrax toxin LF subunit 45 215 4.0E-70 T 29-03-2018 IPR005165 Anthrax toxin, edema factor, central GO:0005576|GO:0008294|GO:0009405 KEGG: 00230+4.6.1.1 MC49_RS11090 2994ef1c1b1f7c2fffe6c162b1285376 393 SUPERFAMILY SSF81298 47 336 3.27E-56 T 29-03-2018 IPR035099 Anthrax toxin, edema factor, C-terminal KEGG: 00230+4.6.1.1 MC49_RS17415 7a7c48a1a20fbd91de629b0c5fe36296 342 Gene3D G3DSA:3.40.630.30 2 132 2.8E-6 T 29-03-2018 MC49_RS17415 7a7c48a1a20fbd91de629b0c5fe36296 342 SUPERFAMILY SSF55729 1 93 8.99E-9 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS09540 08f21aafcb90354e3e7549c9a866ad93 229 Gene3D G3DSA:2.40.160.40 23 229 1.4E-30 T 29-03-2018 MC49_RS09540 08f21aafcb90354e3e7549c9a866ad93 229 SUPERFAMILY SSF56935 41 229 4.81E-10 T 29-03-2018 MC49_RS09540 08f21aafcb90354e3e7549c9a866ad93 229 Pfam PF06178 Oligogalacturonate-specific porin protein (KdgM) 16 229 2.9E-75 T 29-03-2018 IPR009331 Oligogalacturonate-specific porin MC49_RS12830 3bfba3a670d6f31a8d0688d3a16e3317 871 Gene3D G3DSA:3.90.199.10 34 285 4.2E-117 T 29-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 MC49_RS12830 3bfba3a670d6f31a8d0688d3a16e3317 871 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 588 639 2.2E-10 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MC49_RS12830 3bfba3a670d6f31a8d0688d3a16e3317 871 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 648 690 4.5E-8 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MC49_RS12830 3bfba3a670d6f31a8d0688d3a16e3317 871 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 795 841 1.4E-12 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MC49_RS12830 3bfba3a670d6f31a8d0688d3a16e3317 871 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 745 791 1.2E-14 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MC49_RS12830 3bfba3a670d6f31a8d0688d3a16e3317 871 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 538 584 5.1E-10 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MC49_RS12830 3bfba3a670d6f31a8d0688d3a16e3317 871 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 695 739 2.5E-14 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 MC49_RS12830 3bfba3a670d6f31a8d0688d3a16e3317 871 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 32 506 5.3E-153 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MC49_RS12830 3bfba3a670d6f31a8d0688d3a16e3317 871 SUPERFAMILY SSF56719 30 521 1.83E-182 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MC49_RS12830 3bfba3a670d6f31a8d0688d3a16e3317 871 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 2 843 24.721 T 29-03-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MC49_RS12830 3bfba3a670d6f31a8d0688d3a16e3317 871 Gene3D G3DSA:3.90.199.10 286 375 1.3E-8 T 29-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 MC49_RS12830 3bfba3a670d6f31a8d0688d3a16e3317 871 SUPERFAMILY SSF101904 533 850 5.23E-112 T 29-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal MC49_RS12830 3bfba3a670d6f31a8d0688d3a16e3317 871 Gene3D G3DSA:1.10.268.10 376 497 9.7E-50 T 29-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MC49_RS12830 3bfba3a670d6f31a8d0688d3a16e3317 871 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 8 842 0.0 T 29-03-2018 MC49_RS12830 3bfba3a670d6f31a8d0688d3a16e3317 871 SMART SM00434 11 499 2.7E-298 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MC49_RS12830 3bfba3a670d6f31a8d0688d3a16e3317 871 Gene3D G3DSA:2.120.10.90 533 859 1.2E-134 T 29-03-2018 MC49_RS16150 a1be434d93e29543536bba6bcb46142c 180 SUPERFAMILY SSF55021 95 179 2.5E-11 T 29-03-2018 MC49_RS16150 a1be434d93e29543536bba6bcb46142c 180 Pfam PF13740 ACT domain 7 82 2.5E-23 T 29-03-2018 MC49_RS16150 a1be434d93e29543536bba6bcb46142c 180 PIRSF PIRSF028103 5 180 4.2E-55 T 29-03-2018 IPR016867 Glycine cleavage system transcriptional repressor GO:0006355 MC49_RS16150 a1be434d93e29543536bba6bcb46142c 180 Gene3D G3DSA:3.30.70.260 8 87 1.4E-11 T 29-03-2018 MC49_RS16150 a1be434d93e29543536bba6bcb46142c 180 SUPERFAMILY SSF55021 7 84 1.67E-15 T 29-03-2018 MC49_RS16150 a1be434d93e29543536bba6bcb46142c 180 Gene3D G3DSA:3.30.70.260 96 180 5.7E-8 T 29-03-2018 MC49_RS19035 70015cf2881fedfb827c2e99338fc3aa 346 Gene3D G3DSA:1.10.3470.10 13 341 9.8E-37 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like MC49_RS19035 70015cf2881fedfb827c2e99338fc3aa 346 Pfam PF02653 Branched-chain amino acid transport system / permease component 62 335 3.1E-50 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 MC49_RS12410 0e18beda73df7d63fd36d47214fad1b1 231 Pfam PF02308 MgtC family 10 129 1.1E-37 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MC49_RS12410 0e18beda73df7d63fd36d47214fad1b1 231 PRINTS PR01837 MgtC/SapB protein signature 57 79 1.3E-46 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MC49_RS12410 0e18beda73df7d63fd36d47214fad1b1 231 PRINTS PR01837 MgtC/SapB protein signature 13 32 1.3E-46 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MC49_RS12410 0e18beda73df7d63fd36d47214fad1b1 231 PRINTS PR01837 MgtC/SapB protein signature 84 108 1.3E-46 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MC49_RS12410 0e18beda73df7d63fd36d47214fad1b1 231 PRINTS PR01837 MgtC/SapB protein signature 32 50 1.3E-46 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 MC49_RS10915 185fb0cc2a9c2e41ab8775c2a6a61e05 275 Gene3D G3DSA:3.40.50.720 1 148 1.3E-13 T 29-03-2018 MC49_RS10915 185fb0cc2a9c2e41ab8775c2a6a61e05 275 Pfam PF01370 NAD dependent epimerase/dehydratase family 76 213 3.9E-7 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MC49_RS10915 185fb0cc2a9c2e41ab8775c2a6a61e05 275 SUPERFAMILY SSF51735 1 266 1.7E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS10915 185fb0cc2a9c2e41ab8775c2a6a61e05 275 Gene3D G3DSA:3.90.25.10 155 268 2.9E-8 T 29-03-2018 MC49_RS05665 0e4376cc391789adb1976155153e6f2c 167 Gene3D G3DSA:3.40.1280.10 1 164 1.8E-32 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MC49_RS05665 0e4376cc391789adb1976155153e6f2c 167 PIRSF PIRSF029256 1 164 6.5E-65 T 29-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 MC49_RS05665 0e4376cc391789adb1976155153e6f2c 167 Pfam PF00588 SpoU rRNA Methylase family 2 151 2.6E-27 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MC49_RS05665 0e4376cc391789adb1976155153e6f2c 167 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 1 162 2.5E-65 T 29-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 MC49_RS05665 0e4376cc391789adb1976155153e6f2c 167 SUPERFAMILY SSF75217 2 162 1.18E-39 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases MC49_RS05665 0e4376cc391789adb1976155153e6f2c 167 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 161 32.954 T 29-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 MC49_RS10060 ab5a7a700cba4e3b8d945b6ca5817315 360 Gene3D G3DSA:3.40.50.300 141 343 1.2E-9 T 29-03-2018 MC49_RS10060 ab5a7a700cba4e3b8d945b6ca5817315 360 SMART SM00450 4 134 3.8E-7 T 29-03-2018 IPR001763 Rhodanese-like domain MC49_RS10060 ab5a7a700cba4e3b8d945b6ca5817315 360 Hamap MF_01622 tRNA 2-selenouridine synthase [selU]. 3 360 46.578 T 29-03-2018 IPR017582 tRNA 2-selenouridine synthase GO:0016785|GO:0043828|GO:0070329 MC49_RS10060 ab5a7a700cba4e3b8d945b6ca5817315 360 SUPERFAMILY SSF52821 94 156 5.62E-20 T 29-03-2018 IPR001763 Rhodanese-like domain MC49_RS10060 ab5a7a700cba4e3b8d945b6ca5817315 360 SUPERFAMILY SSF52821 11 66 5.62E-20 T 29-03-2018 IPR001763 Rhodanese-like domain MC49_RS10060 ab5a7a700cba4e3b8d945b6ca5817315 360 TIGRFAM TIGR03167 tRNA_sel_U_synt: tRNA 2-selenouridine synthase 17 346 4.2E-100 T 29-03-2018 IPR017582 tRNA 2-selenouridine synthase GO:0016785|GO:0043828|GO:0070329 MC49_RS10060 ab5a7a700cba4e3b8d945b6ca5817315 360 Gene3D G3DSA:3.40.250.10 5 140 1.4E-17 T 29-03-2018 IPR001763 Rhodanese-like domain MC49_RS10060 ab5a7a700cba4e3b8d945b6ca5817315 360 SUPERFAMILY SSF52540 143 269 3.4E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS12005 2866000f2323c66ffc793cb5e6c1e9d1 492 Pfam PF07690 Major Facilitator Superfamily 13 405 1.8E-54 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS12005 2866000f2323c66ffc793cb5e6c1e9d1 492 ProSitePatterns PS00216 Sugar transport proteins signature 1. 63 79 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MC49_RS12005 2866000f2323c66ffc793cb5e6c1e9d1 492 PRINTS PR01036 Tetracycline resistance protein TetB signature 72 94 2.4E-8 T 29-03-2018 MC49_RS12005 2866000f2323c66ffc793cb5e6c1e9d1 492 PRINTS PR01036 Tetracycline resistance protein TetB signature 12 36 2.4E-8 T 29-03-2018 MC49_RS12005 2866000f2323c66ffc793cb5e6c1e9d1 492 PRINTS PR01036 Tetracycline resistance protein TetB signature 134 158 2.4E-8 T 29-03-2018 MC49_RS12005 2866000f2323c66ffc793cb5e6c1e9d1 492 SUPERFAMILY SSF103473 4 193 2.88E-65 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS12005 2866000f2323c66ffc793cb5e6c1e9d1 492 SUPERFAMILY SSF103473 450 484 2.88E-65 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS12005 2866000f2323c66ffc793cb5e6c1e9d1 492 SUPERFAMILY SSF103473 244 415 2.88E-65 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS12005 2866000f2323c66ffc793cb5e6c1e9d1 492 Gene3D G3DSA:1.20.1250.20 1 198 3.5E-31 T 29-03-2018 MC49_RS12005 2866000f2323c66ffc793cb5e6c1e9d1 492 Gene3D G3DSA:1.20.1250.20 248 491 2.9E-27 T 29-03-2018 MC49_RS12005 2866000f2323c66ffc793cb5e6c1e9d1 492 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 9 421 4.8E-74 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 MC49_RS09915 c1158b309c27d8ca4258b141877b15ff 383 SUPERFAMILY SSF55021 277 374 4.03E-22 T 29-03-2018 MC49_RS09915 c1158b309c27d8ca4258b141877b15ff 383 Gene3D G3DSA:3.40.190.10 110 194 3.1E-30 T 29-03-2018 MC49_RS09915 c1158b309c27d8ca4258b141877b15ff 383 Gene3D G3DSA:3.30.70.260 286 380 7.1E-24 T 29-03-2018 MC49_RS09915 c1158b309c27d8ca4258b141877b15ff 383 PIRSF PIRSF001500 1 377 6.2E-132 T 29-03-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 MC49_RS09915 c1158b309c27d8ca4258b141877b15ff 383 SMART SM00830 8 88 3.6E-24 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MC49_RS09915 c1158b309c27d8ca4258b141877b15ff 383 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 322 329 - T 29-03-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 MC49_RS09915 c1158b309c27d8ca4258b141877b15ff 383 TIGRFAM TIGR01797 CM_P_1: chorismate mutase 4 86 8.6E-31 T 29-03-2018 IPR010952 Chorismate mutase, gammaproteobacteria GO:0004106|GO:0005737|GO:0009094 KEGG: 00400+5.4.99.5+4.2.1.51|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7432|MetaCyc: PWY-7626 MC49_RS09915 c1158b309c27d8ca4258b141877b15ff 383 Pfam PF01817 Chorismate mutase type II 8 86 8.6E-17 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MC49_RS09915 c1158b309c27d8ca4258b141877b15ff 383 Gene3D G3DSA:1.20.59.10 1 109 1.1E-27 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MC49_RS09915 c1158b309c27d8ca4258b141877b15ff 383 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 258 280 - T 29-03-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 MC49_RS09915 c1158b309c27d8ca4258b141877b15ff 383 SUPERFAMILY SSF53850 102 288 3.8E-56 T 29-03-2018 MC49_RS09915 c1158b309c27d8ca4258b141877b15ff 383 Gene3D G3DSA:3.40.190.10 195 271 5.0E-22 T 29-03-2018 MC49_RS09915 c1158b309c27d8ca4258b141877b15ff 383 SUPERFAMILY SSF48600 2 91 6.23E-22 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MC49_RS09915 c1158b309c27d8ca4258b141877b15ff 383 Pfam PF00800 Prephenate dehydratase 103 284 4.8E-58 T 29-03-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 MC49_RS11625 61871f556c6cb19ad4a7d68f0aba70e9 259 Pfam PF02633 Creatinine amidohydrolase 8 243 7.1E-51 T 29-03-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 MC49_RS11625 61871f556c6cb19ad4a7d68f0aba70e9 259 Gene3D G3DSA:3.40.50.10310 1 251 2.4E-60 T 29-03-2018 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 MC49_RS11625 61871f556c6cb19ad4a7d68f0aba70e9 259 SUPERFAMILY SSF102215 3 247 1.11E-52 T 29-03-2018 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 MC49_RS10445 51b0cbc032852c1b3ccb45e632b0ff2a 141 Pfam PF02472 Biopolymer transport protein ExbD/TolR 9 140 1.9E-22 T 29-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 MC49_RS03085 e53c101712dc7779b918303632d1847d 405 SUPERFAMILY SSF55031 219 335 1.05E-26 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain MC49_RS03085 e53c101712dc7779b918303632d1847d 405 SUPERFAMILY SSF53187 8 229 7.71E-81 T 29-03-2018 MC49_RS03085 e53c101712dc7779b918303632d1847d 405 SUPERFAMILY SSF53187 342 400 7.71E-81 T 29-03-2018 MC49_RS03085 e53c101712dc7779b918303632d1847d 405 Gene3D G3DSA:3.40.630.10 220 401 1.4E-23 T 29-03-2018 MC49_RS03085 e53c101712dc7779b918303632d1847d 405 Gene3D G3DSA:3.40.630.10 2 219 1.5E-35 T 29-03-2018 MC49_RS03085 e53c101712dc7779b918303632d1847d 405 PIRSF PIRSF001235 9 402 3.0E-123 T 29-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 MC49_RS03085 e53c101712dc7779b918303632d1847d 405 Pfam PF01546 Peptidase family M20/M25/M40 86 399 2.9E-31 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 MC49_RS03085 e53c101712dc7779b918303632d1847d 405 Pfam PF07687 Peptidase dimerisation domain 217 315 1.1E-9 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain MC49_RS03085 e53c101712dc7779b918303632d1847d 405 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 15 399 1.1E-119 T 29-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 MC49_RS13560 ab6dbabc402fe04bb85ac8175a72d428 940 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 401 538 8.4E-12 T 29-03-2018 MC49_RS13560 ab6dbabc402fe04bb85ac8175a72d428 940 PRINTS PR00775 90kDa heat shock protein signature 547 564 2.3E-11 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal MC49_RS13560 ab6dbabc402fe04bb85ac8175a72d428 940 PRINTS PR00775 90kDa heat shock protein signature 373 393 2.3E-11 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal MC49_RS13560 ab6dbabc402fe04bb85ac8175a72d428 940 PRINTS PR00775 90kDa heat shock protein signature 495 517 2.3E-11 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal MC49_RS13560 ab6dbabc402fe04bb85ac8175a72d428 940 PRINTS PR00775 90kDa heat shock protein signature 448 465 2.3E-11 T 29-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal MC49_RS13560 ab6dbabc402fe04bb85ac8175a72d428 940 SUPERFAMILY SSF55874 373 564 5.16E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS13560 ab6dbabc402fe04bb85ac8175a72d428 940 Gene3D G3DSA:3.30.565.10 399 597 4.7E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS05620 083753649f56170dc36f59af87a50f47 353 Gene3D G3DSA:3.40.50.2000 163 348 2.0E-44 T 29-03-2018 MC49_RS05620 083753649f56170dc36f59af87a50f47 353 SUPERFAMILY SSF53756 1 345 2.02E-99 T 29-03-2018 MC49_RS05620 083753649f56170dc36f59af87a50f47 353 Gene3D G3DSA:3.40.50.2000 1 151 4.9E-33 T 29-03-2018 MC49_RS05620 083753649f56170dc36f59af87a50f47 353 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 69 325 1.2E-80 T 29-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 MC49_RS05620 083753649f56170dc36f59af87a50f47 353 TIGRFAM TIGR02195 heptsyl_trn_II: lipopolysaccharide heptosyltransferase II 2 344 2.1E-160 T 29-03-2018 IPR011910 ADP-heptose--LPS heptosyltransferase 2 GO:0009103|GO:0016757 MC49_RS10745 0b8019ff2cee2cf7fc999558853de88e 393 SUPERFAMILY SSF103473 14 382 1.57E-22 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS10745 0b8019ff2cee2cf7fc999558853de88e 393 Pfam PF06779 Uncharacterised MFS-type transporter YbfB 23 380 1.1E-83 T 29-03-2018 IPR010645 Uncharacterised MFS-type transporter YbfB MC49_RS10745 0b8019ff2cee2cf7fc999558853de88e 393 Gene3D G3DSA:1.20.1250.20 14 201 3.6E-8 T 29-03-2018 MC49_RS10745 0b8019ff2cee2cf7fc999558853de88e 393 Gene3D G3DSA:1.20.1250.20 202 382 7.7E-8 T 29-03-2018 MC49_RS05330 18c1ab1a08c71850847912598b13c53a 366 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 120 2.2E-38 T 29-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS05330 18c1ab1a08c71850847912598b13c53a 366 SMART SM00480 17 362 2.7E-164 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS05330 18c1ab1a08c71850847912598b13c53a 366 SUPERFAMILY SSF55979 125 244 2.11E-30 T 29-03-2018 MC49_RS05330 18c1ab1a08c71850847912598b13c53a 366 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 366 6.2E-114 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS05330 18c1ab1a08c71850847912598b13c53a 366 Gene3D G3DSA:3.10.150.10 1 120 1.5E-28 T 29-03-2018 MC49_RS05330 18c1ab1a08c71850847912598b13c53a 366 Gene3D G3DSA:3.10.150.10 124 247 8.5E-33 T 29-03-2018 MC49_RS05330 18c1ab1a08c71850847912598b13c53a 366 SUPERFAMILY SSF55979 1 121 4.04E-28 T 29-03-2018 MC49_RS05330 18c1ab1a08c71850847912598b13c53a 366 PIRSF PIRSF000804 1 366 1.2E-115 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS05330 18c1ab1a08c71850847912598b13c53a 366 SUPERFAMILY SSF55979 245 366 6.73E-38 T 29-03-2018 MC49_RS05330 18c1ab1a08c71850847912598b13c53a 366 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 245 365 6.6E-45 T 29-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS05330 18c1ab1a08c71850847912598b13c53a 366 Gene3D G3DSA:3.10.150.10 248 366 2.3E-26 T 29-03-2018 MC49_RS05330 18c1ab1a08c71850847912598b13c53a 366 Pfam PF02767 DNA polymerase III beta subunit, central domain 130 243 2.1E-38 T 29-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS08285 48466205d9ca5653b8e108ea7322c1e9 383 Pfam PF13265 Protein of unknown function (DUF4056) 48 308 2.0E-126 T 29-03-2018 IPR025130 Protein of unknown function DUF4056 MC49_RS17190 dfd1993dc2073a2768c103ea1189d56b 365 Pfam PF01032 FecCD transport family 46 360 7.4E-84 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 MC49_RS17190 dfd1993dc2073a2768c103ea1189d56b 365 SUPERFAMILY SSF81345 26 360 2.48E-78 T 29-03-2018 IPR029022 ABC transporter, BtuC-like MC49_RS17190 dfd1993dc2073a2768c103ea1189d56b 365 Gene3D G3DSA:1.10.3470.10 30 365 3.3E-68 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like MC49_RS08985 c8457637cc7f80d13db2be5fd18aa35d 308 Gene3D G3DSA:3.40.50.300 1 251 5.0E-62 T 29-03-2018 MC49_RS08985 c8457637cc7f80d13db2be5fd18aa35d 308 SMART SM00382 30 213 6.5E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS08985 c8457637cc7f80d13db2be5fd18aa35d 308 SUPERFAMILY SSF52540 3 237 6.86E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS08985 c8457637cc7f80d13db2be5fd18aa35d 308 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS08985 c8457637cc7f80d13db2be5fd18aa35d 308 Pfam PF00005 ABC transporter 21 165 5.4E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS04345 742dc6c0d76e0097edd21626b71a9ecf 258 SMART SM00382 36 238 3.2E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS04345 742dc6c0d76e0097edd21626b71a9ecf 258 Pfam PF00005 ABC transporter 27 182 2.6E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS04345 742dc6c0d76e0097edd21626b71a9ecf 258 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 12 258 1.9E-119 T 29-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 MC49_RS04345 742dc6c0d76e0097edd21626b71a9ecf 258 SUPERFAMILY SSF52540 11 245 1.42E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS04345 742dc6c0d76e0097edd21626b71a9ecf 258 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS04345 742dc6c0d76e0097edd21626b71a9ecf 258 Gene3D G3DSA:3.40.50.300 8 256 1.0E-62 T 29-03-2018 MC49_RS12815 a2f9924037acfbee98c2b141a13ad90f 376 SUPERFAMILY SSF47240 3 340 1.93E-114 T 29-03-2018 IPR009078 Ferritin-like superfamily MC49_RS12815 a2f9924037acfbee98c2b141a13ad90f 376 Pfam PF00268 Ribonucleotide reductase, small chain 32 332 1.7E-47 T 29-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MC49_RS12815 a2f9924037acfbee98c2b141a13ad90f 376 Gene3D G3DSA:1.10.620.20 1 346 1.2E-114 T 29-03-2018 MC49_RS12815 a2f9924037acfbee98c2b141a13ad90f 376 ProSitePatterns PS00368 Ribonucleotide reductase small subunit signature. 115 131 - T 29-03-2018 IPR030475 Ribonucleotide reductase small subunit, acitve site KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MC49_RS05560 8c6ac1a4099f1b547dd340539e037e91 55 ProSitePatterns PS00582 Ribosomal protein L33 signature. 21 40 - T 29-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS05560 8c6ac1a4099f1b547dd340539e037e91 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 55 4.1E-27 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS05560 8c6ac1a4099f1b547dd340539e037e91 55 Pfam PF00471 Ribosomal protein L33 7 53 3.2E-19 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS05560 8c6ac1a4099f1b547dd340539e037e91 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 5 53 15.857 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS05560 8c6ac1a4099f1b547dd340539e037e91 55 SUPERFAMILY SSF57829 1 53 1.04E-20 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 MC49_RS12355 45aa245f8f5a15605ab6695c84788731 1026 Pfam PF01568 Molydopterin dinucleotide binding domain 892 995 8.3E-14 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 MC49_RS12355 45aa245f8f5a15605ab6695c84788731 1026 Gene3D G3DSA:2.20.25.90 72 154 8.7E-13 T 29-03-2018 MC49_RS12355 45aa245f8f5a15605ab6695c84788731 1026 Gene3D G3DSA:3.40.50.740 462 794 1.1E-32 T 29-03-2018 MC49_RS12355 45aa245f8f5a15605ab6695c84788731 1026 Pfam PF00384 Molybdopterin oxidoreductase 243 685 2.8E-14 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS12355 45aa245f8f5a15605ab6695c84788731 1026 Gene3D G3DSA:3.40.50.740 158 379 3.0E-19 T 29-03-2018 MC49_RS12355 45aa245f8f5a15605ab6695c84788731 1026 SMART SM00926 71 153 1.4E-13 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS12355 45aa245f8f5a15605ab6695c84788731 1026 Gene3D G3DSA:2.40.40.20 850 1026 2.2E-27 T 29-03-2018 MC49_RS12355 45aa245f8f5a15605ab6695c84788731 1026 SUPERFAMILY SSF50692 875 999 5.2E-26 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain MC49_RS12355 45aa245f8f5a15605ab6695c84788731 1026 SUPERFAMILY SSF53706 137 870 1.22E-111 T 29-03-2018 MC49_RS12355 45aa245f8f5a15605ab6695c84788731 1026 SUPERFAMILY SSF53706 75 110 1.22E-111 T 29-03-2018 MC49_RS12145 5f04de18e77c8501e63e8f7ece276309 431 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 110 421 7.8E-106 T 29-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MC49_RS12145 5f04de18e77c8501e63e8f7ece276309 431 SUPERFAMILY SSF53187 108 427 2.51E-104 T 29-03-2018 MC49_RS12145 5f04de18e77c8501e63e8f7ece276309 431 PRINTS PR00481 Cytosol aminopeptidase signature 250 271 8.4E-45 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MC49_RS12145 5f04de18e77c8501e63e8f7ece276309 431 PRINTS PR00481 Cytosol aminopeptidase signature 213 234 8.4E-45 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MC49_RS12145 5f04de18e77c8501e63e8f7ece276309 431 PRINTS PR00481 Cytosol aminopeptidase signature 272 292 8.4E-45 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MC49_RS12145 5f04de18e77c8501e63e8f7ece276309 431 PRINTS PR00481 Cytosol aminopeptidase signature 300 315 8.4E-45 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MC49_RS12145 5f04de18e77c8501e63e8f7ece276309 431 PRINTS PR00481 Cytosol aminopeptidase signature 191 208 8.4E-45 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MC49_RS12145 5f04de18e77c8501e63e8f7ece276309 431 PIRSF PIRSF036388 2 431 4.9E-218 T 29-03-2018 IPR008330 Peptidase M17, peptidase B GO:0004177|GO:0005737|GO:0006508|GO:0008235|GO:0030145 KEGG: 00480+3.4.11.23 MC49_RS12145 5f04de18e77c8501e63e8f7ece276309 431 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 276 283 - T 29-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MC49_RS12145 5f04de18e77c8501e63e8f7ece276309 431 Pfam PF12404 Peptidase 6 82 3.7E-31 T 29-03-2018 IPR008330 Peptidase M17, peptidase B GO:0004177|GO:0005737|GO:0006508|GO:0008235|GO:0030145 KEGG: 00480+3.4.11.23 MC49_RS12145 5f04de18e77c8501e63e8f7ece276309 431 Gene3D G3DSA:3.40.630.10 94 431 1.5E-114 T 29-03-2018 MC49_RS10515 b29457ccf6620ec5b47286019dc96e9b 483 SMART SM00382 280 474 3.1E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS10515 b29457ccf6620ec5b47286019dc96e9b 483 SMART SM00382 28 219 2.4E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS10515 b29457ccf6620ec5b47286019dc96e9b 483 Gene3D G3DSA:3.40.50.300 2 242 1.5E-28 T 29-03-2018 MC49_RS10515 b29457ccf6620ec5b47286019dc96e9b 483 SUPERFAMILY SSF52540 22 224 3.47E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS10515 b29457ccf6620ec5b47286019dc96e9b 483 SUPERFAMILY SSF52540 257 469 3.99E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS10515 b29457ccf6620ec5b47286019dc96e9b 483 Pfam PF00005 ABC transporter 271 423 4.0E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS10515 b29457ccf6620ec5b47286019dc96e9b 483 Pfam PF00005 ABC transporter 23 162 4.1E-18 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS10515 b29457ccf6620ec5b47286019dc96e9b 483 Gene3D G3DSA:3.40.50.300 243 480 2.7E-39 T 29-03-2018 MC49_RS16010 f543c7153369f4e0c24972e3c0f27cc3 291 SUPERFAMILY SSF81345 6 261 1.96E-38 T 29-03-2018 IPR029022 ABC transporter, BtuC-like MC49_RS16010 f543c7153369f4e0c24972e3c0f27cc3 291 Pfam PF00950 ABC 3 transport family 11 265 8.1E-87 T 29-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 MC49_RS16010 f543c7153369f4e0c24972e3c0f27cc3 291 Gene3D G3DSA:1.10.3470.10 2 273 7.7E-28 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like MC49_RS11745 3e4afa36330484fe646c085b748766b4 553 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 552 5.4E-159 T 29-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 MC49_RS11745 3e4afa36330484fe646c085b748766b4 553 SUPERFAMILY SSF52540 1 199 7.27E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS11745 3e4afa36330484fe646c085b748766b4 553 SUPERFAMILY SSF52540 351 512 7.27E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS11745 3e4afa36330484fe646c085b748766b4 553 SUPERFAMILY SSF52540 287 322 7.27E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS11745 3e4afa36330484fe646c085b748766b4 553 PIRSF PIRSF003128 1 553 1.6E-152 T 29-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 MC49_RS11745 3e4afa36330484fe646c085b748766b4 553 Gene3D G3DSA:3.40.50.300 1 533 4.3E-42 T 29-03-2018 MC49_RS11745 3e4afa36330484fe646c085b748766b4 553 Pfam PF02463 RecF/RecN/SMC N terminal domain 1 512 2.9E-19 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal MC49_RS04730 b556b389d411758cc0a77df69ffe6c48 841 Gene3D G3DSA:3.40.710.10 416 789 2.7E-94 T 29-03-2018 MC49_RS04730 b556b389d411758cc0a77df69ffe6c48 841 Pfam PF00912 Transglycosylase 55 229 7.2E-65 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 MC49_RS04730 b556b389d411758cc0a77df69ffe6c48 841 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 65 776 6.7E-175 T 29-03-2018 MC49_RS04730 b556b389d411758cc0a77df69ffe6c48 841 Gene3D G3DSA:2.40.50.140 348 415 2.4E-22 T 29-03-2018 MC49_RS04730 b556b389d411758cc0a77df69ffe6c48 841 SUPERFAMILY SSF56601 211 233 8.16E-111 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MC49_RS04730 b556b389d411758cc0a77df69ffe6c48 841 SUPERFAMILY SSF56601 262 313 8.16E-111 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MC49_RS04730 b556b389d411758cc0a77df69ffe6c48 841 SUPERFAMILY SSF56601 422 609 8.16E-111 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MC49_RS04730 b556b389d411758cc0a77df69ffe6c48 841 SUPERFAMILY SSF56601 675 821 8.16E-111 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MC49_RS04730 b556b389d411758cc0a77df69ffe6c48 841 Pfam PF00905 Penicillin binding protein transpeptidase domain 428 602 8.9E-21 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MC49_RS04730 b556b389d411758cc0a77df69ffe6c48 841 Pfam PF17092 Penicillin-binding protein OB-like domain 316 425 1.8E-30 T 29-03-2018 IPR031376 Penicillin-binding protein, OB-like domain MC49_RS04730 b556b389d411758cc0a77df69ffe6c48 841 SUPERFAMILY SSF53955 43 256 1.15E-80 T 29-03-2018 IPR023346 Lysozyme-like domain MC49_RS04730 b556b389d411758cc0a77df69ffe6c48 841 Gene3D G3DSA:1.10.3810.10 47 246 7.8E-82 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 MC49_RS14150 cba8dc68b01bbf406c6b5e57c9f03538 334 SUPERFAMILY SSF56524 75 330 4.58E-94 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 MC49_RS14150 cba8dc68b01bbf406c6b5e57c9f03538 334 Pfam PF00174 Oxidoreductase molybdopterin binding domain 107 267 6.3E-32 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 MC49_RS14150 cba8dc68b01bbf406c6b5e57c9f03538 334 Gene3D G3DSA:3.90.420.10 64 334 1.9E-66 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 MC49_RS14150 cba8dc68b01bbf406c6b5e57c9f03538 334 Hamap MF_01206 Protein-methionine-sulfoxide reductase catalytic subunit MsrP [msrP]. 2 334 54.505 T 29-03-2018 IPR022867 Protein-methionine-sulfoxide reductase subunit MsrP GO:0016667|GO:0030091|GO:0043546|GO:0055114 MC49_RS11830 3f1accbf1e985d30c9cfffcdb8d47e09 330 Pfam PF10502 Signal peptidase, peptidase S26 268 307 5.3E-5 T 29-03-2018 IPR019533 Peptidase S26 MC49_RS11830 3f1accbf1e985d30c9cfffcdb8d47e09 330 ProSitePatterns PS00761 Signal peptidases I signature 3. 275 288 - T 29-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 MC49_RS11830 3f1accbf1e985d30c9cfffcdb8d47e09 330 ProSitePatterns PS00760 Signal peptidases I lysine active site. 146 158 - T 29-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 MC49_RS11830 3f1accbf1e985d30c9cfffcdb8d47e09 330 ProSitePatterns PS00501 Signal peptidases I serine active site. 89 96 - T 29-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 MC49_RS11830 3f1accbf1e985d30c9cfffcdb8d47e09 330 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 270 289 2.4E-26 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MC49_RS11830 3f1accbf1e985d30c9cfffcdb8d47e09 330 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 80 96 2.4E-26 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MC49_RS11830 3f1accbf1e985d30c9cfffcdb8d47e09 330 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 144 156 2.4E-26 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MC49_RS11830 3f1accbf1e985d30c9cfffcdb8d47e09 330 Pfam PF00717 Peptidase S24-like 86 158 1.3E-21 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MC49_RS11830 3f1accbf1e985d30c9cfffcdb8d47e09 330 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 66 158 1.5E-26 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MC49_RS11830 3f1accbf1e985d30c9cfffcdb8d47e09 330 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 265 310 1.8E-17 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MC49_RS11830 3f1accbf1e985d30c9cfffcdb8d47e09 330 Gene3D G3DSA:2.10.109.10 76 326 5.1E-55 T 29-03-2018 MC49_RS11830 3f1accbf1e985d30c9cfffcdb8d47e09 330 SUPERFAMILY SSF51306 78 328 5.62E-73 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MC49_RS00735 670d9d25d639b4269be4576ae51cabe3 91 SUPERFAMILY SSF47729 1 90 2.8E-32 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 MC49_RS00735 670d9d25d639b4269be4576ae51cabe3 91 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 29-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 MC49_RS00735 670d9d25d639b4269be4576ae51cabe3 91 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 2.7E-20 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MC49_RS00735 670d9d25d639b4269be4576ae51cabe3 91 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 2.7E-20 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MC49_RS00735 670d9d25d639b4269be4576ae51cabe3 91 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 2.7E-20 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MC49_RS00735 670d9d25d639b4269be4576ae51cabe3 91 SMART SM00411 1 90 1.8E-43 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MC49_RS00735 670d9d25d639b4269be4576ae51cabe3 91 Gene3D G3DSA:4.10.520.10 1 91 2.6E-33 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 MC49_RS00735 670d9d25d639b4269be4576ae51cabe3 91 Pfam PF00216 Bacterial DNA-binding protein 1 90 2.4E-32 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MC49_RS11195 bfeb4ea53311bd0522a937b7e2033e7d 225 SUPERFAMILY SSF52499 12 210 3.79E-46 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 MC49_RS11195 bfeb4ea53311bd0522a937b7e2033e7d 225 Pfam PF00857 Isochorismatase family 21 172 5.7E-20 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 MC49_RS11195 bfeb4ea53311bd0522a937b7e2033e7d 225 Gene3D G3DSA:3.40.50.850 9 215 4.4E-37 T 29-03-2018 MC49_RS12470 99aacbb3b0102f04bad96bf231ddc218 212 Gene3D G3DSA:1.10.287.500 39 167 2.6E-12 T 29-03-2018 MC49_RS12470 99aacbb3b0102f04bad96bf231ddc218 212 Gene3D G3DSA:1.20.5.590 10 37 5.3E-10 T 29-03-2018 MC49_RS12470 99aacbb3b0102f04bad96bf231ddc218 212 PIRSF PIRSF002884 1 212 7.9E-62 T 29-03-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 MC49_RS12470 99aacbb3b0102f04bad96bf231ddc218 212 SUPERFAMILY SSF75708 13 211 1.12E-51 T 29-03-2018 MC49_RS12470 99aacbb3b0102f04bad96bf231ddc218 212 Pfam PF04344 Chemotaxis phosphatase, CheZ 19 212 5.5E-63 T 29-03-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 MC49_RS16635 9d3685bdbe7feb5069337d3b60c41d4d 273 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 15 250 5.8E-78 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS16635 9d3685bdbe7feb5069337d3b60c41d4d 273 Gene3D G3DSA:3.30.70.580 10 116 1.1E-36 T 29-03-2018 MC49_RS16635 9d3685bdbe7feb5069337d3b60c41d4d 273 Gene3D G3DSA:3.30.70.660 117 254 1.7E-37 T 29-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS16635 9d3685bdbe7feb5069337d3b60c41d4d 273 Pfam PF01416 tRNA pseudouridine synthase 20 114 9.1E-9 T 29-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS16635 9d3685bdbe7feb5069337d3b60c41d4d 273 Pfam PF01416 tRNA pseudouridine synthase 154 256 2.4E-29 T 29-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS16635 9d3685bdbe7feb5069337d3b60c41d4d 273 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 13 255 36.038 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS16635 9d3685bdbe7feb5069337d3b60c41d4d 273 PIRSF PIRSF001430 12 266 4.9E-80 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS16635 9d3685bdbe7feb5069337d3b60c41d4d 273 SUPERFAMILY SSF55120 12 267 2.59E-94 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS14355 7553ad02b4638ba7ddc9cee00d8ced36 201 SUPERFAMILY SSF52218 1 199 4.19E-51 T 29-03-2018 IPR029039 Flavoprotein-like domain MC49_RS14355 7553ad02b4638ba7ddc9cee00d8ced36 201 Pfam PF02525 Flavodoxin-like fold 3 196 3.3E-42 T 29-03-2018 IPR003680 Flavodoxin-like fold MC49_RS14355 7553ad02b4638ba7ddc9cee00d8ced36 201 Gene3D G3DSA:3.40.50.360 2 201 4.0E-38 T 29-03-2018 IPR029039 Flavoprotein-like domain MC49_RS14355 7553ad02b4638ba7ddc9cee00d8ced36 201 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 200 29.758 T 29-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 MC49_RS11045 82c414beab496611018b16c9d215007d 239 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 34 201 4.9E-70 T 29-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 MC49_RS11045 82c414beab496611018b16c9d215007d 239 SUPERFAMILY SSF55729 3 227 1.06E-89 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS11045 82c414beab496611018b16c9d215007d 239 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 239 93.213 T 29-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 MC49_RS11045 82c414beab496611018b16c9d215007d 239 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 35 214 2.9E-71 T 29-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 MC49_RS14155 04cdb6193414f601ce6c60f001be7367 204 Hamap MF_01207 Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ [msrQ]. 6 200 19.562 T 29-03-2018 IPR022837 Protein-methionine-sulfoxide reductase subunit MsrQ GO:0005887|GO:0030091 MC49_RS14155 04cdb6193414f601ce6c60f001be7367 204 Pfam PF01794 Ferric reductase like transmembrane component 50 160 2.2E-16 T 29-03-2018 IPR013130 Ferric reductase transmembrane component-like domain MC49_RS15360 6a11691c22148eeb77926d08dc5d0694 301 Gene3D G3DSA:3.90.550.10 1 301 1.1E-56 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MC49_RS15360 6a11691c22148eeb77926d08dc5d0694 301 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 8 277 1.4E-111 T 29-03-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 MC49_RS15360 6a11691c22148eeb77926d08dc5d0694 301 SUPERFAMILY SSF53448 9 290 4.96E-60 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MC49_RS15360 6a11691c22148eeb77926d08dc5d0694 301 Pfam PF00483 Nucleotidyl transferase 10 278 6.8E-24 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MC49_RS12395 781bcab734ae0707ec3d4e742067fa51 169 Pfam PF10777 Inner membrane protein YlaC 1 153 1.2E-68 T 29-03-2018 IPR019713 Inner membrane protein YlaC MC49_RS12255 2bfb5da52f48abcf2a69f1956988c328 280 Gene3D G3DSA:1.10.3720.10 13 279 4.1E-36 T 29-03-2018 MC49_RS12255 2bfb5da52f48abcf2a69f1956988c328 280 SUPERFAMILY SSF161098 12 263 3.14E-49 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS12255 2bfb5da52f48abcf2a69f1956988c328 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 261 3.2E-12 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS12255 2bfb5da52f48abcf2a69f1956988c328 280 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 10 265 2.9E-96 T 29-03-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 MC49_RS12255 2bfb5da52f48abcf2a69f1956988c328 280 TIGRFAM TIGR02140 permease_CysW: sulfate ABC transporter, permease protein CysW 14 266 1.0E-106 T 29-03-2018 IPR011866 Sulphate ABC transporter, permease protein CysW GO:0008272|GO:0015116|GO:0016021 MC49_RS06130 0a89bdb08965460e4849691c1fa8365e 339 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 336 3.6E-46 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS06130 0a89bdb08965460e4849691c1fa8365e 339 Gene3D G3DSA:1.10.3720.10 3 325 3.8E-48 T 29-03-2018 MC49_RS06130 0a89bdb08965460e4849691c1fa8365e 339 SUPERFAMILY SSF161098 89 160 8.18E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS06130 0a89bdb08965460e4849691c1fa8365e 339 SUPERFAMILY SSF161098 200 321 8.18E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS12425 a657886886f69ba85f172a74c971a2fc 295 Pfam PF01618 MotA/TolQ/ExbB proton channel family 138 238 4.3E-10 T 29-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 MC49_RS12425 a657886886f69ba85f172a74c971a2fc 295 TIGRFAM TIGR03818 MotA1: flagellar motor stator protein MotA 2 281 1.6E-110 T 29-03-2018 IPR022522 Flagellar motor stator, MotA MC49_RS12425 a657886886f69ba85f172a74c971a2fc 295 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 205 222 - T 29-03-2018 IPR000540 Flagellar motor protein MotA, conserved site MC49_RS13745 faa995c8d4fa6837117ff4211742113d 142 Gene3D G3DSA:3.40.50.620 1 142 2.0E-29 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS13745 faa995c8d4fa6837117ff4211742113d 142 SUPERFAMILY SSF52402 2 142 1.0E-30 T 29-03-2018 MC49_RS13745 faa995c8d4fa6837117ff4211742113d 142 PIRSF PIRSF006276 1 142 1.3E-19 T 29-03-2018 IPR006015 Universal stress protein A MC49_RS13745 faa995c8d4fa6837117ff4211742113d 142 Pfam PF00582 Universal stress protein family 1 142 1.6E-27 T 29-03-2018 IPR006016 UspA GO:0006950 MC49_RS13745 faa995c8d4fa6837117ff4211742113d 142 PRINTS PR01438 Universal stress protein signature 2 20 8.2E-14 T 29-03-2018 IPR006015 Universal stress protein A MC49_RS13745 faa995c8d4fa6837117ff4211742113d 142 PRINTS PR01438 Universal stress protein signature 120 142 8.2E-14 T 29-03-2018 IPR006015 Universal stress protein A MC49_RS13745 faa995c8d4fa6837117ff4211742113d 142 PRINTS PR01438 Universal stress protein signature 103 115 8.2E-14 T 29-03-2018 IPR006015 Universal stress protein A MC49_RS14715 a95fd790bb0723414b1502be2cd01dba 381 SUPERFAMILY SSF103473 5 374 5.89E-54 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS14715 a95fd790bb0723414b1502be2cd01dba 381 Pfam PF07690 Major Facilitator Superfamily 10 220 9.9E-34 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS14715 a95fd790bb0723414b1502be2cd01dba 381 Gene3D G3DSA:1.20.1250.20 198 380 4.9E-13 T 29-03-2018 MC49_RS14715 a95fd790bb0723414b1502be2cd01dba 381 Gene3D G3DSA:1.20.1250.20 5 192 3.7E-32 T 29-03-2018 MC49_RS17230 2bc91444a61d26b3cb5686057b317806 140 Gene3D G3DSA:3.90.79.10 2 132 4.0E-30 T 29-03-2018 MC49_RS17230 2bc91444a61d26b3cb5686057b317806 140 Pfam PF00293 NUDIX domain 5 127 5.9E-26 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MC49_RS17230 2bc91444a61d26b3cb5686057b317806 140 ProSitePatterns PS00893 Nudix box signature. 36 57 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MC49_RS17230 2bc91444a61d26b3cb5686057b317806 140 PRINTS PR00502 NUDIX hydrolase family signature 31 45 3.2E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MC49_RS17230 2bc91444a61d26b3cb5686057b317806 140 PRINTS PR00502 NUDIX hydrolase family signature 45 60 3.2E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MC49_RS17230 2bc91444a61d26b3cb5686057b317806 140 SUPERFAMILY SSF55811 4 135 8.53E-32 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MC49_RS06065 20bdb400fd578569590aa27be7197982 91 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 60 6.1E-28 T 29-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS06065 20bdb400fd578569590aa27be7197982 91 SMART SM01409 8 61 2.6E-14 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 MC49_RS06065 20bdb400fd578569590aa27be7197982 91 Pfam PF01192 RNA polymerase Rpb6 10 59 5.6E-16 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 MC49_RS06065 20bdb400fd578569590aa27be7197982 91 SUPERFAMILY SSF63562 1 79 1.67E-24 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 MC49_RS06065 20bdb400fd578569590aa27be7197982 91 Gene3D G3DSA:3.90.940.10 1 91 3.6E-28 T 29-03-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 MC49_RS06065 20bdb400fd578569590aa27be7197982 91 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 62 16.29 T 29-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS15145 32c98374f16918a5725fe2ed35d10251 289 Gene3D G3DSA:3.20.20.140 10 265 8.3E-43 T 29-03-2018 MC49_RS15145 32c98374f16918a5725fe2ed35d10251 289 SMART SM00481 13 80 1.8E-16 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal MC49_RS15145 32c98374f16918a5725fe2ed35d10251 289 SUPERFAMILY SSF89550 175 285 7.72E-52 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 MC49_RS15145 32c98374f16918a5725fe2ed35d10251 289 SUPERFAMILY SSF89550 13 93 7.72E-52 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 MC49_RS15145 32c98374f16918a5725fe2ed35d10251 289 Pfam PF02811 PHP domain 14 143 5.7E-9 T 29-03-2018 IPR004013 PHP domain GO:0003824 MC49_RS00920 6f9c2a334b10dfb0edc3c17772c3291d 229 Pfam PF00072 Response regulator receiver domain 5 117 1.7E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS00920 6f9c2a334b10dfb0edc3c17772c3291d 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 225 9.2E-30 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MC49_RS00920 6f9c2a334b10dfb0edc3c17772c3291d 229 SUPERFAMILY SSF52172 3 126 5.55E-42 T 29-03-2018 IPR011006 CheY-like superfamily MC49_RS00920 6f9c2a334b10dfb0edc3c17772c3291d 229 Gene3D G3DSA:3.40.50.2300 2 123 8.1E-35 T 29-03-2018 MC49_RS00920 6f9c2a334b10dfb0edc3c17772c3291d 229 SMART SM00448 3 116 1.9E-43 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS00920 6f9c2a334b10dfb0edc3c17772c3291d 229 Gene3D G3DSA:1.10.10.10 124 229 5.7E-36 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS00920 6f9c2a334b10dfb0edc3c17772c3291d 229 SMART SM00862 150 225 1.7E-28 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MC49_RS00920 6f9c2a334b10dfb0edc3c17772c3291d 229 SUPERFAMILY SSF46894 127 226 2.78E-33 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MC49_RS00920 6f9c2a334b10dfb0edc3c17772c3291d 229 TIGRFAM TIGR02154 PhoB: phosphate regulon transcriptional regulatory protein PhoB 1 226 8.3E-112 T 29-03-2018 IPR011879 Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB GO:0000156|GO:0000160|GO:0003677|GO:0006817 MC49_RS12800 d6f65d73b19da4199d20ad2794b6656f 393 PIRSF PIRSF001434 1 390 4.4E-114 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MC49_RS12800 d6f65d73b19da4199d20ad2794b6656f 393 Gene3D G3DSA:3.90.1150.10 258 392 1.4E-33 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS12800 d6f65d73b19da4199d20ad2794b6656f 393 TIGRFAM TIGR01324 cysta_beta_ly_B: cystathionine beta-lyase 13 389 3.3E-146 T 29-03-2018 IPR006233 Cystathionine beta-lyase, bacterial GO:0004121|GO:0005737|GO:0006520 KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 MC49_RS12800 d6f65d73b19da4199d20ad2794b6656f 393 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 13 387 5.7E-98 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MC49_RS12800 d6f65d73b19da4199d20ad2794b6656f 393 Gene3D G3DSA:3.40.640.10 9 257 2.4E-41 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS12800 d6f65d73b19da4199d20ad2794b6656f 393 SUPERFAMILY SSF53383 46 388 1.21E-89 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS18115 5a26c15332b43cdba231f2341930351e 422 TIGRFAM TIGR00804 nupC: nucleoside transporter, NupC family 5 419 4.4E-139 T 29-03-2018 IPR018270 Concentrative nucleoside transporter, metazoan/bacterial GO:0005337|GO:0016020|GO:1901642 Reactome: R-HSA-83936 MC49_RS18115 5a26c15332b43cdba231f2341930351e 422 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 81 3.0E-21 T 29-03-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 MC49_RS18115 5a26c15332b43cdba231f2341930351e 422 Pfam PF07670 Nucleoside recognition 99 194 2.9E-7 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 MC49_RS18115 5a26c15332b43cdba231f2341930351e 422 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 201 419 5.0E-72 T 29-03-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 MC49_RS04610 54c60080cb0fc60950ec40e2c6167e6a 351 SUPERFAMILY SSF49401 211 350 4.97E-12 T 29-03-2018 IPR008966 Adhesion domain MC49_RS04610 54c60080cb0fc60950ec40e2c6167e6a 351 Gene3D G3DSA:2.60.40.1090 199 351 1.1E-12 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS04610 54c60080cb0fc60950ec40e2c6167e6a 351 Pfam PF00419 Fimbrial protein 202 350 1.3E-10 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS07800 057e492bdc3142bf719050b848e350af 432 SUPERFAMILY SSF109998 26 200 9.03E-40 T 29-03-2018 IPR027304 Trigger factor/SurA domain MC49_RS07800 057e492bdc3142bf719050b848e350af 432 Pfam PF00639 PPIC-type PPIASE domain 179 272 1.9E-21 T 29-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 MC49_RS07800 057e492bdc3142bf719050b848e350af 432 Pfam PF00639 PPIC-type PPIASE domain 290 383 3.2E-26 T 29-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 MC49_RS07800 057e492bdc3142bf719050b848e350af 432 SUPERFAMILY SSF54534 174 276 3.01E-28 T 29-03-2018 MC49_RS07800 057e492bdc3142bf719050b848e350af 432 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 322 343 - T 29-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 MC49_RS07800 057e492bdc3142bf719050b848e350af 432 Gene3D G3DSA:1.10.4030.10 22 149 9.7E-24 T 29-03-2018 MC49_RS07800 057e492bdc3142bf719050b848e350af 432 Hamap MF_01183 Chaperone SurA [surA]. 7 429 33.497 T 29-03-2018 IPR023034 Peptidyl-prolyl isomerase SurA GO:0003755|GO:0006457|GO:0030288|GO:0042277|GO:0042710|GO:0043165|GO:0050821|GO:0051082|GO:0051085|GO:0060274 MC49_RS07800 057e492bdc3142bf719050b848e350af 432 SUPERFAMILY SSF54534 284 386 1.9E-32 T 29-03-2018 MC49_RS07800 057e492bdc3142bf719050b848e350af 432 Pfam PF09312 SurA N-terminal domain 26 143 2.3E-40 T 29-03-2018 IPR015391 SurA N-terminal MC49_RS07800 057e492bdc3142bf719050b848e350af 432 Gene3D G3DSA:3.10.50.40 164 279 1.4E-24 T 29-03-2018 MC49_RS07800 057e492bdc3142bf719050b848e350af 432 Gene3D G3DSA:3.10.50.40 280 421 1.8E-32 T 29-03-2018 MC49_RS06590 2e601c8bf7a784ebade720a54f17367c 309 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 36 289 4.0E-108 T 29-03-2018 MC49_RS06590 2e601c8bf7a784ebade720a54f17367c 309 PIRSF PIRSF000450 1 308 1.2E-144 T 29-03-2018 IPR033752 MetA family KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 MC49_RS06590 2e601c8bf7a784ebade720a54f17367c 309 Hamap MF_00295 Homoserine O-succinyltransferase [metA]. 1 301 52.438 T 29-03-2018 IPR005697 Homoserine O-succinyltransferase MetA GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 MC49_RS06590 2e601c8bf7a784ebade720a54f17367c 309 Pfam PF04204 Homoserine O-succinyltransferase 2 299 7.5E-133 T 29-03-2018 IPR033752 MetA family KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 MC49_RS06590 2e601c8bf7a784ebade720a54f17367c 309 Gene3D G3DSA:3.40.50.880 34 301 9.2E-42 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MC49_RS06590 2e601c8bf7a784ebade720a54f17367c 309 TIGRFAM TIGR01001 metA: homoserine O-succinyltransferase 1 301 3.1E-151 T 29-03-2018 IPR005697 Homoserine O-succinyltransferase MetA GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 MC49_RS06590 2e601c8bf7a784ebade720a54f17367c 309 SUPERFAMILY SSF52317 17 297 4.2E-100 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MC49_RS09650 418bbe97fc68b12548b8b0acc34983bd 203 SUPERFAMILY SSF52833 5 181 2.16E-21 T 29-03-2018 IPR012336 Thioredoxin-like fold MC49_RS09650 418bbe97fc68b12548b8b0acc34983bd 203 Gene3D G3DSA:3.40.30.10 1 195 2.9E-19 T 29-03-2018 MC49_RS01565 545fb7b82c8036dd243f7b20ac336460 187 TIGRFAM TIGR01670 KdsC-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family 25 178 1.1E-68 T 29-03-2018 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 MC49_RS01565 545fb7b82c8036dd243f7b20ac336460 187 Gene3D G3DSA:3.40.50.1000 6 187 3.1E-25 T 29-03-2018 IPR023214 HAD-like domain MC49_RS01565 545fb7b82c8036dd243f7b20ac336460 187 PIRSF PIRSF006118 12 187 7.4E-72 T 29-03-2018 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 MC49_RS01565 545fb7b82c8036dd243f7b20ac336460 187 SUPERFAMILY SSF56784 21 180 6.98E-40 T 29-03-2018 IPR023214 HAD-like domain MC49_RS01565 545fb7b82c8036dd243f7b20ac336460 187 Pfam PF08282 haloacid dehalogenase-like hydrolase 92 158 7.9E-8 T 29-03-2018 IPR023214 HAD-like domain MC49_RS12315 621ce0a0f3651d53af61990b85ffb2c4 239 Gene3D G3DSA:1.10.10.60 132 189 2.6E-8 T 29-03-2018 MC49_RS12315 621ce0a0f3651d53af61990b85ffb2c4 239 SMART SM00342 152 235 3.8E-24 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MC49_RS12315 621ce0a0f3651d53af61990b85ffb2c4 239 Gene3D G3DSA:2.60.120.10 7 89 2.6E-7 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MC49_RS12315 621ce0a0f3651d53af61990b85ffb2c4 239 SUPERFAMILY SSF51182 15 157 1.83E-11 T 29-03-2018 IPR011051 RmlC-like cupin domain MC49_RS12315 621ce0a0f3651d53af61990b85ffb2c4 239 Gene3D G3DSA:1.10.10.60 190 238 4.2E-11 T 29-03-2018 MC49_RS12315 621ce0a0f3651d53af61990b85ffb2c4 239 Pfam PF12833 Helix-turn-helix domain 162 235 3.2E-18 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MC49_RS12315 621ce0a0f3651d53af61990b85ffb2c4 239 SUPERFAMILY SSF46689 189 235 3.0E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS16595 8b99d175e56c240853e59b7e6face6b8 303 Gene3D G3DSA:3.40.50.720 1 302 5.3E-37 T 29-03-2018 MC49_RS16595 8b99d175e56c240853e59b7e6face6b8 303 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 218 8.7E-22 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MC49_RS16595 8b99d175e56c240853e59b7e6face6b8 303 SUPERFAMILY SSF51735 1 298 7.63E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS16595 8b99d175e56c240853e59b7e6face6b8 303 Pfam PF08338 Domain of unknown function (DUF1731) 250 296 9.0E-18 T 29-03-2018 IPR013549 Domain of unknown function DUF1731 MC49_RS16595 8b99d175e56c240853e59b7e6face6b8 303 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 293 1.5E-108 T 29-03-2018 IPR010099 Epimerase family protein SDR39U1 MC49_RS15810 0474786714c6b41bf2e4f7f6efea534f 248 SMART SM00382 26 223 9.3E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS15810 0474786714c6b41bf2e4f7f6efea534f 248 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 2 244 7.9E-112 T 29-03-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 MC49_RS15810 0474786714c6b41bf2e4f7f6efea534f 248 Gene3D G3DSA:3.40.50.300 1 248 9.1E-43 T 29-03-2018 MC49_RS15810 0474786714c6b41bf2e4f7f6efea534f 248 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS15810 0474786714c6b41bf2e4f7f6efea534f 248 Pfam PF00005 ABC transporter 17 172 1.0E-20 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS15810 0474786714c6b41bf2e4f7f6efea534f 248 SUPERFAMILY SSF52540 2 230 5.58E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS11405 5bd97b11056fa624c5787c82d73a6a96 93 SUPERFAMILY SSF55729 6 89 3.92E-21 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS11405 5bd97b11056fa624c5787c82d73a6a96 93 Gene3D G3DSA:3.40.630.30 1 92 6.4E-17 T 29-03-2018 MC49_RS11405 5bd97b11056fa624c5787c82d73a6a96 93 Pfam PF14542 GCN5-related N-acetyl-transferase 10 89 4.8E-21 T 29-03-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase MC49_RS03685 642fb095ad020fd1fdbf9674a1cb2287 298 Pfam PF00892 EamA-like transporter family 8 142 1.7E-15 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MC49_RS03685 642fb095ad020fd1fdbf9674a1cb2287 298 SUPERFAMILY SSF103481 42 145 6.02E-14 T 29-03-2018 MC49_RS03685 642fb095ad020fd1fdbf9674a1cb2287 298 SUPERFAMILY SSF103481 187 285 1.7E-7 T 29-03-2018 MC49_RS03685 642fb095ad020fd1fdbf9674a1cb2287 298 TIGRFAM TIGR00688 rarD: protein RarD 8 260 8.2E-97 T 29-03-2018 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 MC49_RS16645 9865f21bcb362283107e2eca20031cc5 376 Gene3D G3DSA:3.40.50.720 1 102 4.3E-21 T 29-03-2018 MC49_RS16645 9865f21bcb362283107e2eca20031cc5 376 Hamap MF_01825 Erythronate-4-phosphate dehydrogenase [pdxB]. 1 357 46.47 T 29-03-2018 IPR020921 Erythronate-4-phosphate dehydrogenase GO:0005737|GO:0008615|GO:0033711|GO:0055114 KEGG: 00260+1.1.1.29|KEGG: 00630+1.1.1.29|KEGG: 00680+1.1.1.29|KEGG: 00750+1.1.1.290|MetaCyc: PWY-181 MC49_RS16645 9865f21bcb362283107e2eca20031cc5 376 Gene3D G3DSA:3.40.50.720 103 259 8.2E-33 T 29-03-2018 MC49_RS16645 9865f21bcb362283107e2eca20031cc5 376 SUPERFAMILY SSF51735 91 257 6.79E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS16645 9865f21bcb362283107e2eca20031cc5 376 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 197 213 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site MC49_RS16645 9865f21bcb362283107e2eca20031cc5 376 Pfam PF11890 Domain of unknown function (DUF3410) 289 369 1.7E-27 T 29-03-2018 IPR024531 Erythronate-4-phosphate dehydrogenase, dimerisation domain GO:0046983 KEGG: 00260+1.1.1.29|KEGG: 00630+1.1.1.29|KEGG: 00680+1.1.1.29|KEGG: 00750+1.1.1.290|MetaCyc: PWY-181 MC49_RS16645 9865f21bcb362283107e2eca20031cc5 376 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 35 278 2.6E-17 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 MC49_RS16645 9865f21bcb362283107e2eca20031cc5 376 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 256 1.2E-34 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MC49_RS16645 9865f21bcb362283107e2eca20031cc5 376 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 119 146 - T 29-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 MC49_RS16645 9865f21bcb362283107e2eca20031cc5 376 SUPERFAMILY SSF52283 4 110 2.98E-17 T 29-03-2018 MC49_RS08915 87ec865204b3f909a4f2d784d0fbcc04 215 SUPERFAMILY SSF46689 14 77 2.24E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS08915 87ec865204b3f909a4f2d784d0fbcc04 215 Gene3D G3DSA:1.10.10.60 9 50 5.8E-12 T 29-03-2018 MC49_RS08915 87ec865204b3f909a4f2d784d0fbcc04 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 64 6.7E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS08915 87ec865204b3f909a4f2d784d0fbcc04 215 Gene3D G3DSA:1.10.10.60 51 126 1.3E-10 T 29-03-2018 MC49_RS18955 55e03c524e938d848e86aee82d8eeab3 282 Gene3D G3DSA:3.90.550.10 14 240 1.2E-9 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MC49_RS18955 55e03c524e938d848e86aee82d8eeab3 282 Pfam PF00535 Glycosyl transferase family 2 48 158 2.3E-5 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MC49_RS18955 55e03c524e938d848e86aee82d8eeab3 282 SUPERFAMILY SSF53448 50 196 3.94E-13 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MC49_RS16490 c2de870748138d3e51e086cd5ded09ef 100 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 8 95 1.6E-21 T 29-03-2018 MC49_RS16490 c2de870748138d3e51e086cd5ded09ef 100 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 2 100 18.26 T 29-03-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 MC49_RS07405 3f20c2d5055e79f3f37f8195054360ea 225 Gene3D G3DSA:2.60.260.20 2 81 8.6E-22 T 29-03-2018 MC49_RS07405 3f20c2d5055e79f3f37f8195054360ea 225 SUPERFAMILY SSF69287 3 79 3.53E-16 T 29-03-2018 IPR004029 UreE urease accessory, N-terminal MC49_RS07405 3f20c2d5055e79f3f37f8195054360ea 225 SMART SM00988 11 75 3.0E-9 T 29-03-2018 IPR004029 UreE urease accessory, N-terminal MC49_RS07405 3f20c2d5055e79f3f37f8195054360ea 225 Hamap MF_00822 Urease accessory protein UreE [ureE]. 2 170 15.063 T 29-03-2018 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 MC49_RS07405 3f20c2d5055e79f3f37f8195054360ea 225 Pfam PF02814 UreE urease accessory protein, N-terminal domain 15 72 5.2E-17 T 29-03-2018 IPR004029 UreE urease accessory, N-terminal MC49_RS07405 3f20c2d5055e79f3f37f8195054360ea 225 PIRSF PIRSF036402 2 225 8.2E-23 T 29-03-2018 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 MC49_RS15900 1457c5048ca76464d5f4a36bf41732c1 161 SUPERFAMILY SSF54001 41 161 1.96E-39 T 29-03-2018 MC49_RS15900 1457c5048ca76464d5f4a36bf41732c1 161 Gene3D G3DSA:2.30.260.10 89 159 4.9E-21 T 29-03-2018 MC49_RS15900 1457c5048ca76464d5f4a36bf41732c1 161 Gene3D G3DSA:3.90.1720.10 19 88 9.2E-13 T 29-03-2018 MC49_RS15900 1457c5048ca76464d5f4a36bf41732c1 161 Pfam PF00877 NlpC/P60 family 54 160 2.8E-28 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain MC49_RS02170 f5414924d324e648deba4a6569ea8fb2 309 Pfam PF08401 Domain of unknown function (DUF1738) 15 138 1.9E-38 T 29-03-2018 IPR013610 Domain of unknown function DUF1738 MC49_RS02170 f5414924d324e648deba4a6569ea8fb2 309 PIRSF PIRSF037112 1 309 4.4E-108 T 29-03-2018 IPR017113 Antirestriction, ArdC MC49_RS11160 3f937a4f218f528a7ea6cb0815b6c374 58 Hamap MF_01187 UPF0434 protein YcaR [ycaR]. 1 54 27.286 T 29-03-2018 IPR005651 Uncharacterised protein family UPF0434/Trm112 MC49_RS11160 3f937a4f218f528a7ea6cb0815b6c374 58 SUPERFAMILY SSF158997 1 53 2.22E-20 T 29-03-2018 MC49_RS11160 3f937a4f218f528a7ea6cb0815b6c374 58 Gene3D G3DSA:2.20.25.10 8 53 7.6E-20 T 29-03-2018 MC49_RS11160 3f937a4f218f528a7ea6cb0815b6c374 58 Pfam PF03966 Trm112p-like protein 2 40 1.1E-10 T 29-03-2018 IPR005651 Uncharacterised protein family UPF0434/Trm112 MC49_RS18170 b7d869debe7a384eebc0fb3a1649e470 350 Gene3D G3DSA:3.30.428.10 165 348 3.0E-48 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 MC49_RS18170 b7d869debe7a384eebc0fb3a1649e470 350 SUPERFAMILY SSF54197 3 177 1.05E-69 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 MC49_RS18170 b7d869debe7a384eebc0fb3a1649e470 350 ProSitePatterns PS00117 Galactose-1-phosphate uridyl transferase family 1 active site signature. 151 168 - T 29-03-2018 IPR019779 Galactose-1-phosphate uridyl transferase, class I His-active site KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 MC49_RS18170 b7d869debe7a384eebc0fb3a1649e470 350 PIRSF PIRSF000808 1 344 1.2E-116 T 29-03-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 MC49_RS18170 b7d869debe7a384eebc0fb3a1649e470 350 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 2 348 4.5E-169 T 29-03-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 MC49_RS18170 b7d869debe7a384eebc0fb3a1649e470 350 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 186 347 9.5E-60 T 29-03-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 MC49_RS18170 b7d869debe7a384eebc0fb3a1649e470 350 SUPERFAMILY SSF54197 181 347 4.35E-48 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 MC49_RS18170 b7d869debe7a384eebc0fb3a1649e470 350 Gene3D G3DSA:3.30.428.10 45 164 7.4E-48 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 MC49_RS18170 b7d869debe7a384eebc0fb3a1649e470 350 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 4 176 2.9E-65 T 29-03-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 MC49_RS02275 6e700991b10a0bfe80e034d98d217d3e 219 TIGRFAM TIGR03746 conj_TIGR03746: integrating conjugative element protein, PFL_4703 family 4 204 9.7E-88 T 29-03-2018 IPR021548 Protein of unknown function DUF2895 MC49_RS02275 6e700991b10a0bfe80e034d98d217d3e 219 Pfam PF11444 Protein of unknown function (DUF2895) 6 203 1.3E-84 T 29-03-2018 IPR021548 Protein of unknown function DUF2895 MC49_RS08300 52f65f804eacc1c3e1865df6c466eee9 490 Pfam PF00939 Sodium:sulfate symporter transmembrane region 13 490 1.0E-138 T 29-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 MC49_RS08300 52f65f804eacc1c3e1865df6c466eee9 490 PIRSF PIRSF002457 2 490 1.9E-135 T 29-03-2018 IPR030676 Citrate carrier CitT-related MC49_RS08300 52f65f804eacc1c3e1865df6c466eee9 490 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 27 484 1.7E-114 T 29-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 MC49_RS09725 70e0b69460cca2fc6fe58c1b3731efdc 198 TIGRFAM TIGR01940 nqrE: NADH:ubiquinone oxidoreductase, Na(+)-translocating, E subunit 2 197 1.3E-103 T 29-03-2018 IPR010967 Na(+)-translocating NADH-quinone reductase subunit E GO:0009276|GO:0016021|GO:0016655|GO:0022904|GO:0055114 MC49_RS09725 70e0b69460cca2fc6fe58c1b3731efdc 198 Pfam PF02508 Rnf-Nqr subunit, membrane protein 4 196 5.9E-59 T 29-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 MC49_RS09725 70e0b69460cca2fc6fe58c1b3731efdc 198 PIRSF PIRSF006102 1 198 6.3E-64 T 29-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 MC49_RS09725 70e0b69460cca2fc6fe58c1b3731efdc 198 Hamap MF_00429 Na(+)-translocating NADH-quinone reductase subunit E [nqrE]. 1 198 29.462 T 29-03-2018 IPR010967 Na(+)-translocating NADH-quinone reductase subunit E GO:0009276|GO:0016021|GO:0016655|GO:0022904|GO:0055114 MC49_RS13650 adba98033e918cc307e1f396f4c38a82 459 Gene3D G3DSA:3.60.120.10 3 456 6.3E-153 T 29-03-2018 IPR005801 ADC synthase GO:0009058 MC49_RS13650 adba98033e918cc307e1f396f4c38a82 459 PRINTS PR00095 Anthranilate synthase component I signature 388 402 1.3E-16 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MC49_RS13650 adba98033e918cc307e1f396f4c38a82 459 PRINTS PR00095 Anthranilate synthase component I signature 308 321 1.3E-16 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MC49_RS13650 adba98033e918cc307e1f396f4c38a82 459 PRINTS PR00095 Anthranilate synthase component I signature 403 417 1.3E-16 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MC49_RS13650 adba98033e918cc307e1f396f4c38a82 459 PRINTS PR00095 Anthranilate synthase component I signature 294 307 1.3E-16 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MC49_RS13650 adba98033e918cc307e1f396f4c38a82 459 SUPERFAMILY SSF56322 7 454 1.83E-140 T 29-03-2018 IPR005801 ADC synthase GO:0009058 MC49_RS13650 adba98033e918cc307e1f396f4c38a82 459 Pfam PF00425 chorismate binding enzyme 192 446 1.2E-91 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal MC49_RS13650 adba98033e918cc307e1f396f4c38a82 459 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 109 447 3.1E-122 T 29-03-2018 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 MC49_RS13650 adba98033e918cc307e1f396f4c38a82 459 Pfam PF04715 Anthranilate synthase component I, N terminal region 20 155 5.6E-28 T 29-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MC49_RS02370 e447653e71e0b093364e956045162dab 315 Pfam PF00419 Fimbrial protein 179 315 4.0E-9 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS02370 e447653e71e0b093364e956045162dab 315 SUPERFAMILY SSF49401 180 313 2.73E-13 T 29-03-2018 IPR008966 Adhesion domain MC49_RS02370 e447653e71e0b093364e956045162dab 315 Gene3D G3DSA:2.60.40.1090 175 313 5.3E-13 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS15755 b24640c5b0bc564f4eb7a6286dca8b7e 387 PIRSF PIRSF003085 2 382 9.3E-122 T 29-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 MC49_RS15755 b24640c5b0bc564f4eb7a6286dca8b7e 387 SUPERFAMILY SSF53335 117 374 1.08E-74 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS15755 b24640c5b0bc564f4eb7a6286dca8b7e 387 Gene3D G3DSA:3.40.50.150 104 375 1.8E-60 T 29-03-2018 MC49_RS15755 b24640c5b0bc564f4eb7a6286dca8b7e 387 Pfam PF02353 Mycolic acid cyclopropane synthetase 109 372 3.1E-96 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS10085 070fbad4cc5e7ac247de40e730cc3a8d 210 Gene3D G3DSA:3.30.930.10 1 204 1.5E-59 T 29-03-2018 MC49_RS10085 070fbad4cc5e7ac247de40e730cc3a8d 210 PIRSF PIRSF016262 1 210 3.4E-56 T 29-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MC49_RS10085 070fbad4cc5e7ac247de40e730cc3a8d 210 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 75 128 1.0E-19 T 29-03-2018 MC49_RS10085 070fbad4cc5e7ac247de40e730cc3a8d 210 SUPERFAMILY SSF55681 4 205 5.97E-68 T 29-03-2018 MC49_RS10085 070fbad4cc5e7ac247de40e730cc3a8d 210 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 27 202 9.6E-70 T 29-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MC49_RS10085 070fbad4cc5e7ac247de40e730cc3a8d 210 Hamap MF_00013 Octanoyltransferase [lipB]. 5 206 36.635 T 29-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MC49_RS10085 070fbad4cc5e7ac247de40e730cc3a8d 210 Pfam PF03099 Biotin/lipoate A/B protein ligase family 63 159 3.3E-7 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 MC49_RS10085 070fbad4cc5e7ac247de40e730cc3a8d 210 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 71 86 - T 29-03-2018 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 MC49_RS11495 4ac10cc431e97449cc9a9835a8449bbf 304 Gene3D G3DSA:3.20.80.10 130 304 6.9E-16 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain MC49_RS11495 4ac10cc431e97449cc9a9835a8449bbf 304 Gene3D G3DSA:1.10.10.60 7 61 6.0E-14 T 29-03-2018 MC49_RS11495 4ac10cc431e97449cc9a9835a8449bbf 304 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 59 104 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MC49_RS11495 4ac10cc431e97449cc9a9835a8449bbf 304 SUPERFAMILY SSF55136 133 281 1.12E-13 T 29-03-2018 MC49_RS11495 4ac10cc431e97449cc9a9835a8449bbf 304 Pfam PF12833 Helix-turn-helix domain 31 109 2.4E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MC49_RS11495 4ac10cc431e97449cc9a9835a8449bbf 304 Gene3D G3DSA:1.10.10.60 62 119 6.6E-12 T 29-03-2018 MC49_RS11495 4ac10cc431e97449cc9a9835a8449bbf 304 SMART SM00342 25 108 1.9E-31 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MC49_RS11495 4ac10cc431e97449cc9a9835a8449bbf 304 Pfam PF14526 Integron-associated effector binding protein 133 302 5.5E-36 T 29-03-2018 IPR029441 Integron-associated effector binding protein MC49_RS11495 4ac10cc431e97449cc9a9835a8449bbf 304 SUPERFAMILY SSF46689 10 59 9.31E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS11495 4ac10cc431e97449cc9a9835a8449bbf 304 SUPERFAMILY SSF46689 61 112 2.78E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS02380 4772546d4b2aa3b9073a868f8e771cd3 178 SUPERFAMILY SSF49401 24 139 1.44E-5 T 29-03-2018 IPR008966 Adhesion domain MC49_RS02380 4772546d4b2aa3b9073a868f8e771cd3 178 Gene3D G3DSA:2.60.40.1090 23 164 1.6E-7 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS02380 4772546d4b2aa3b9073a868f8e771cd3 178 Pfam PF00419 Fimbrial protein 25 130 4.6E-6 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS04680 4b553be111ab774cdaab6306f32ad910 239 Gene3D G3DSA:3.40.50.1000 2 41 0.0023 T 29-03-2018 IPR023214 HAD-like domain MC49_RS04680 4b553be111ab774cdaab6306f32ad910 239 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 108 193 1.8E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MC49_RS04680 4b553be111ab774cdaab6306f32ad910 239 Gene3D G3DSA:1.10.150.240 42 88 3.9E-15 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 MC49_RS04680 4b553be111ab774cdaab6306f32ad910 239 Gene3D G3DSA:3.40.50.1000 89 230 4.3E-30 T 29-03-2018 IPR023214 HAD-like domain MC49_RS04680 4b553be111ab774cdaab6306f32ad910 239 Pfam PF13419 Haloacid dehalogenase-like hydrolase 17 199 2.9E-36 T 29-03-2018 IPR023214 HAD-like domain MC49_RS04680 4b553be111ab774cdaab6306f32ad910 239 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 81 200 1.4E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MC49_RS04680 4b553be111ab774cdaab6306f32ad910 239 SUPERFAMILY SSF56784 10 229 3.51E-55 T 29-03-2018 IPR023214 HAD-like domain MC49_RS04680 4b553be111ab774cdaab6306f32ad910 239 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 144 160 2.6E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MC49_RS04680 4b553be111ab774cdaab6306f32ad910 239 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 13 24 2.6E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MC49_RS04680 4b553be111ab774cdaab6306f32ad910 239 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 113 126 2.6E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MC49_RS04680 4b553be111ab774cdaab6306f32ad910 239 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 162 182 2.6E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MC49_RS04680 4b553be111ab774cdaab6306f32ad910 239 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 16 229 1.2E-63 T 29-03-2018 IPR006346 2-phosphoglycolate phosphatase, prokaryotic GO:0008967|GO:0046295 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 MC49_RS10865 d18df5f68fe2d86a16a0465f8fdf4896 165 Pfam PF04073 Aminoacyl-tRNA editing domain 28 151 9.8E-24 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MC49_RS10865 d18df5f68fe2d86a16a0465f8fdf4896 165 SUPERFAMILY SSF55826 7 160 7.98E-35 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MC49_RS10865 d18df5f68fe2d86a16a0465f8fdf4896 165 Gene3D G3DSA:3.90.960.10 5 164 4.0E-36 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MC49_RS10505 5e174aaca2d7435c3c2a8a366143cc3e 250 SMART SM00855 5 191 2.6E-29 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MC49_RS10505 5e174aaca2d7435c3c2a8a366143cc3e 250 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 5 248 1.0E-126 T 29-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 MC49_RS10505 5e174aaca2d7435c3c2a8a366143cc3e 250 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 143 227 7.7E-5 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MC49_RS10505 5e174aaca2d7435c3c2a8a366143cc3e 250 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 128 2.0E-31 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MC49_RS10505 5e174aaca2d7435c3c2a8a366143cc3e 250 Gene3D G3DSA:3.40.50.1240 2 250 5.4E-69 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MC49_RS10505 5e174aaca2d7435c3c2a8a366143cc3e 250 SUPERFAMILY SSF53254 4 247 3.74E-78 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MC49_RS10505 5e174aaca2d7435c3c2a8a366143cc3e 250 PIRSF PIRSF000709 3 114 1.4E-9 T 29-03-2018 MC49_RS10505 5e174aaca2d7435c3c2a8a366143cc3e 250 PIRSF PIRSF000709 174 238 0.029 T 29-03-2018 MC49_RS10505 5e174aaca2d7435c3c2a8a366143cc3e 250 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 3 230 45.627 T 29-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 MC49_RS10505 5e174aaca2d7435c3c2a8a366143cc3e 250 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 8 17 - T 29-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 MC49_RS01750 61b88ae45e2eb601c99e2b4d2a499392 446 Pfam PF03605 Anaerobic c4-dicarboxylate membrane transporter 6 376 3.6E-148 T 29-03-2018 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 MC49_RS01750 61b88ae45e2eb601c99e2b4d2a499392 446 TIGRFAM TIGR00770 Dcu: transporter, anaerobic C4-dicarboxylate uptake (Dcu) family 6 443 1.5E-189 T 29-03-2018 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 MC49_RS01750 61b88ae45e2eb601c99e2b4d2a499392 446 PIRSF PIRSF004539 1 444 2.5E-191 T 29-03-2018 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 MC49_RS09330 68f0c50e5d17888da0521a7e533089df 489 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 9 483 9.6E-183 T 29-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 MC49_RS09330 68f0c50e5d17888da0521a7e533089df 489 SUPERFAMILY SSF103473 12 208 7.98E-27 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS09330 68f0c50e5d17888da0521a7e533089df 489 SUPERFAMILY SSF103473 245 486 7.98E-27 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS09330 68f0c50e5d17888da0521a7e533089df 489 ProSitePatterns PS01022 PTR2 family proton/oligopeptide symporters signature 1. 70 94 - T 29-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 MC49_RS09330 68f0c50e5d17888da0521a7e533089df 489 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 145 157 - T 29-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 MC49_RS09330 68f0c50e5d17888da0521a7e533089df 489 Gene3D G3DSA:1.20.1250.20 3 199 3.3E-25 T 29-03-2018 MC49_RS09330 68f0c50e5d17888da0521a7e533089df 489 Hamap MF_01879 Dipeptide and tripeptide permease B [dtpB]. 3 486 43.983 T 29-03-2018 IPR023778 Amino acid/peptide transporter family, dipeptide/tripeptide permease B MC49_RS09330 68f0c50e5d17888da0521a7e533089df 489 Pfam PF00854 POT family 82 441 1.1E-85 T 29-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 MC49_RS09330 68f0c50e5d17888da0521a7e533089df 489 Gene3D G3DSA:1.20.1250.20 255 489 1.1E-12 T 29-03-2018 MC49_RS10270 055766634dd6d7dfece1cc82b3b96a8b 387 SUPERFAMILY SSF51556 54 355 1.12E-97 T 29-03-2018 IPR032466 Metal-dependent hydrolase MC49_RS10270 055766634dd6d7dfece1cc82b3b96a8b 387 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 1 382 6.0E-151 T 29-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 MC49_RS10270 055766634dd6d7dfece1cc82b3b96a8b 387 Gene3D G3DSA:3.20.20.140 69 355 3.3E-89 T 29-03-2018 MC49_RS10270 055766634dd6d7dfece1cc82b3b96a8b 387 SUPERFAMILY SSF51338 1 53 4.03E-18 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS10270 055766634dd6d7dfece1cc82b3b96a8b 387 PIRSF PIRSF038994 1 387 3.5E-112 T 29-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 MC49_RS10270 055766634dd6d7dfece1cc82b3b96a8b 387 Pfam PF01979 Amidohydrolase family 50 384 4.4E-39 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MC49_RS10270 055766634dd6d7dfece1cc82b3b96a8b 387 Gene3D G3DSA:2.30.40.10 2 68 1.3E-11 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS02025 77f53b228283d0efdceff9b018119101 260 Gene3D G3DSA:3.40.50.700 26 181 2.1E-27 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS02025 77f53b228283d0efdceff9b018119101 260 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 130 146 - T 29-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS02025 77f53b228283d0efdceff9b018119101 260 SUPERFAMILY SSF56770 35 167 4.45E-48 T 29-03-2018 MC49_RS02025 77f53b228283d0efdceff9b018119101 260 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 47 155 7.9E-22 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS05920 78e0e7a2415c50bdddf251879dd15fa3 107 Pfam PF03797 Autotransporter beta-domain 2 84 2.4E-12 T 29-03-2018 IPR005546 Autotransporter beta-domain MC49_RS05920 78e0e7a2415c50bdddf251879dd15fa3 107 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 1 107 2.8E-27 T 29-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 MC49_RS05920 78e0e7a2415c50bdddf251879dd15fa3 107 SUPERFAMILY SSF103515 3 107 2.48E-12 T 29-03-2018 IPR005546 Autotransporter beta-domain MC49_RS05920 78e0e7a2415c50bdddf251879dd15fa3 107 Gene3D G3DSA:2.40.128.130 1 107 1.8E-14 T 29-03-2018 MC49_RS15800 2c093b68135f6a073497e9a1be20d68d 412 Gene3D G3DSA:3.90.1150.10 290 407 2.1E-40 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS15800 2c093b68135f6a073497e9a1be20d68d 412 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 8 411 6.6E-170 T 29-03-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 MC49_RS15800 2c093b68135f6a073497e9a1be20d68d 412 Pfam PF00266 Aminotransferase class-V 25 400 2.9E-144 T 29-03-2018 IPR000192 Aminotransferase class V domain MC49_RS15800 2c093b68135f6a073497e9a1be20d68d 412 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 223 242 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site MC49_RS15800 2c093b68135f6a073497e9a1be20d68d 412 Gene3D G3DSA:3.40.640.10 33 289 1.8E-58 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS15800 2c093b68135f6a073497e9a1be20d68d 412 SUPERFAMILY SSF53383 6 409 2.18E-119 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS15285 118b03f432e4c7735e250f23495c6dcf 306 Gene3D G3DSA:1.10.3720.10 2 294 2.1E-44 T 29-03-2018 MC49_RS15285 118b03f432e4c7735e250f23495c6dcf 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 306 1.4E-39 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS15285 118b03f432e4c7735e250f23495c6dcf 306 SUPERFAMILY SSF161098 88 290 9.03E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS08245 9355033cdd8279cf961b3e5a185f381e 253 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 3 233 1.2E-71 T 29-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 MC49_RS08245 9355033cdd8279cf961b3e5a185f381e 253 Pfam PF01975 Survival protein SurE 4 181 7.4E-58 T 29-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 MC49_RS08245 9355033cdd8279cf961b3e5a185f381e 253 Gene3D G3DSA:3.40.1210.10 1 248 3.2E-81 T 29-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 MC49_RS08245 9355033cdd8279cf961b3e5a185f381e 253 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 2 250 38.674 T 29-03-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 MC49_RS08245 9355033cdd8279cf961b3e5a185f381e 253 SUPERFAMILY SSF64167 2 247 1.07E-81 T 29-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 MC49_RS05475 bd38b31586fe52b291066fccb7565d1c 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 116 134 2.5E-44 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MC49_RS05475 bd38b31586fe52b291066fccb7565d1c 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 137 153 2.5E-44 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MC49_RS05475 bd38b31586fe52b291066fccb7565d1c 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 156 169 2.5E-44 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MC49_RS05475 bd38b31586fe52b291066fccb7565d1c 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 200 209 2.5E-44 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MC49_RS05475 bd38b31586fe52b291066fccb7565d1c 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 91 102 2.5E-44 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MC49_RS05475 bd38b31586fe52b291066fccb7565d1c 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 172 185 2.5E-44 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MC49_RS05475 bd38b31586fe52b291066fccb7565d1c 319 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 5 319 48.657 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MC49_RS05475 bd38b31586fe52b291066fccb7565d1c 319 SUPERFAMILY SSF52096 6 318 9.38E-103 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MC49_RS05475 bd38b31586fe52b291066fccb7565d1c 319 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 6 151 7.0E-61 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MC49_RS05475 bd38b31586fe52b291066fccb7565d1c 319 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 2 319 4.6E-152 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 MC49_RS05475 bd38b31586fe52b291066fccb7565d1c 319 Gene3D G3DSA:3.90.226.10 14 316 5.8E-63 T 29-03-2018 MC49_RS12485 6e0e19d3cb4963731e0e075a3001ed69 698 Pfam PF00771 FHIPEP family 31 687 1.1E-263 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MC49_RS12485 6e0e19d3cb4963731e0e075a3001ed69 698 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 147 170 - T 29-03-2018 IPR025505 FHIPEP conserved site MC49_RS12485 6e0e19d3cb4963731e0e075a3001ed69 698 PIRSF PIRSF005419 11 697 5.3E-237 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MC49_RS12485 6e0e19d3cb4963731e0e075a3001ed69 698 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 23 696 3.6E-270 T 29-03-2018 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 MC49_RS12485 6e0e19d3cb4963731e0e075a3001ed69 698 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 142 158 2.7E-56 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MC49_RS12485 6e0e19d3cb4963731e0e075a3001ed69 698 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 75 94 2.7E-56 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MC49_RS12485 6e0e19d3cb4963731e0e075a3001ed69 698 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 161 179 2.7E-56 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MC49_RS12485 6e0e19d3cb4963731e0e075a3001ed69 698 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 191 208 2.7E-56 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MC49_RS12485 6e0e19d3cb4963731e0e075a3001ed69 698 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 242 256 2.7E-56 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MC49_RS12485 6e0e19d3cb4963731e0e075a3001ed69 698 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 38 51 2.7E-56 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MC49_RS12505 0aefd0dd197f1f2c3ae3cfecd918f679 106 TIGRFAM TIGR03824 FlgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM 1 91 3.6E-14 T 29-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 MC49_RS12505 0aefd0dd197f1f2c3ae3cfecd918f679 106 SUPERFAMILY SSF101498 25 90 4.97E-10 T 29-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 MC49_RS12505 0aefd0dd197f1f2c3ae3cfecd918f679 106 Pfam PF04316 Anti-sigma-28 factor, FlgM 54 89 5.0E-10 T 29-03-2018 IPR031316 Anti-sigma-28 factor FlgM, C-terminal MC49_RS12505 0aefd0dd197f1f2c3ae3cfecd918f679 106 Gene3D G3DSA:1.10.287.1160 61 90 2.3E-10 T 29-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 MC49_RS09585 34558b0d0ba07d879562b6c95f6a5ed9 308 Pfam PF04960 Glutaminase 24 308 9.6E-114 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 MC49_RS09585 34558b0d0ba07d879562b6c95f6a5ed9 308 TIGRFAM TIGR03814 Gln_ase: glutaminase A 10 308 4.8E-128 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 MC49_RS09585 34558b0d0ba07d879562b6c95f6a5ed9 308 Gene3D G3DSA:3.40.710.10 2 308 4.4E-123 T 29-03-2018 MC49_RS09585 34558b0d0ba07d879562b6c95f6a5ed9 308 Hamap MF_00313 Glutaminase [glsA]. 6 308 47.336 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 MC49_RS09585 34558b0d0ba07d879562b6c95f6a5ed9 308 SUPERFAMILY SSF56601 6 308 3.76E-114 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MC49_RS09065 97869d80505ebc027c05fa2da6b2343e 218 Pfam PF01292 Prokaryotic cytochrome b561 14 187 1.8E-19 T 29-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 MC49_RS09065 97869d80505ebc027c05fa2da6b2343e 218 SUPERFAMILY SSF81342 4 213 1.23E-56 T 29-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 MC49_RS09065 97869d80505ebc027c05fa2da6b2343e 218 TIGRFAM TIGR01583 formate-DH-gamm: formate dehydrogenase, gamma subunit 8 206 3.8E-67 T 29-03-2018 IPR006471 Formate dehydrogenase, gamma subunit GO:0008863|GO:0009326|GO:0016021|GO:0045333 MC49_RS09065 97869d80505ebc027c05fa2da6b2343e 218 Gene3D G3DSA:1.20.950.20 1 218 4.6E-56 T 29-03-2018 MC49_RS04860 50f9e99c74e15603f0a00501ae14283d 73 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 23 64 9.7E-6 T 29-03-2018 IPR010260 DNA-binding transcriptional activator AlpA MC49_RS04860 50f9e99c74e15603f0a00501ae14283d 73 Gene3D G3DSA:1.10.10.10 21 71 1.3E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS14485 a1bab8a9b64245224afc64cf67935f06 161 Gene3D G3DSA:3.40.630.30 3 160 2.0E-9 T 29-03-2018 MC49_RS14485 a1bab8a9b64245224afc64cf67935f06 161 SUPERFAMILY SSF55729 8 140 7.77E-13 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS14485 a1bab8a9b64245224afc64cf67935f06 161 Pfam PF13302 Acetyltransferase (GNAT) domain 8 113 2.1E-6 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MC49_RS05995 12fa91c7aceedd609c88a843b1f2f6e5 456 TIGRFAM TIGR00538 hemN: oxygen-independent coproporphyrinogen III oxidase 7 456 5.0E-217 T 29-03-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 MC49_RS05995 12fa91c7aceedd609c88a843b1f2f6e5 456 SMART SM00729 51 271 9.8E-58 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MC49_RS05995 12fa91c7aceedd609c88a843b1f2f6e5 456 SUPERFAMILY SSF102114 5 443 8.11E-146 T 29-03-2018 MC49_RS05995 12fa91c7aceedd609c88a843b1f2f6e5 456 Pfam PF04055 Radical SAM superfamily 56 226 1.6E-17 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MC49_RS05995 12fa91c7aceedd609c88a843b1f2f6e5 456 PIRSF PIRSF000167 3 453 2.0E-173 T 29-03-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 MC49_RS05995 12fa91c7aceedd609c88a843b1f2f6e5 456 Gene3D G3DSA:3.20.20.70 33 352 9.4E-46 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS05995 12fa91c7aceedd609c88a843b1f2f6e5 456 Pfam PF06969 HemN C-terminal domain 362 430 1.4E-11 T 29-03-2018 IPR010723 HemN, C-terminal MC49_RS10225 20e9c2c06121109b725064d278ae3a81 393 Gene3D G3DSA:3.50.50.60 5 364 2.7E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS10225 20e9c2c06121109b725064d278ae3a81 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 9 31 1.7E-19 T 29-03-2018 MC49_RS10225 20e9c2c06121109b725064d278ae3a81 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 282 297 1.7E-19 T 29-03-2018 MC49_RS10225 20e9c2c06121109b725064d278ae3a81 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 297 313 1.7E-19 T 29-03-2018 MC49_RS10225 20e9c2c06121109b725064d278ae3a81 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 159 174 1.7E-19 T 29-03-2018 MC49_RS10225 20e9c2c06121109b725064d278ae3a81 393 SUPERFAMILY SSF51905 269 386 2.98E-61 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS10225 20e9c2c06121109b725064d278ae3a81 393 SUPERFAMILY SSF51905 9 180 2.98E-61 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS10225 20e9c2c06121109b725064d278ae3a81 393 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 10 392 6.4E-119 T 29-03-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 MC49_RS10225 20e9c2c06121109b725064d278ae3a81 393 Pfam PF01494 FAD binding domain 9 342 5.3E-28 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 MC49_RS00010 326cc56baadbf1270776b660aaf9506c 453 Pfam PF00860 Permease family 28 406 1.9E-111 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 MC49_RS00010 326cc56baadbf1270776b660aaf9506c 453 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 356 376 - T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 MC49_RS00010 326cc56baadbf1270776b660aaf9506c 453 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 25 439 2.9E-122 T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 MC49_RS00010 326cc56baadbf1270776b660aaf9506c 453 TIGRFAM TIGR03173 pbuX: xanthine permease 32 442 9.1E-149 T 29-03-2018 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 MC49_RS12595 627288bc81e8387a077d16540ff2b768 155 TIGRFAM TIGR03500 FliO_TIGR: flagellar biosynthetic protein FliO 52 119 3.9E-19 T 29-03-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 MC49_RS12595 627288bc81e8387a077d16540ff2b768 155 Pfam PF04347 Flagellar biosynthesis protein, FliO 63 140 6.4E-17 T 29-03-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 MC49_RS06480 27e15ac460a16e115a1ddfb6cacd9694 649 Pfam PF13667 ThiC-associated domain 46 127 1.8E-34 T 29-03-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MC49_RS06480 27e15ac460a16e115a1ddfb6cacd9694 649 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 166 618 9.6E-224 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MC49_RS06480 27e15ac460a16e115a1ddfb6cacd9694 649 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 166 620 56.432 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MC49_RS06480 27e15ac460a16e115a1ddfb6cacd9694 649 Pfam PF01964 Radical SAM ThiC family 167 615 5.7E-200 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MC49_RS17040 2ecc514fb4841226a790f619d0eefb72 340 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 7 304 4.0E-94 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MC49_RS17040 2ecc514fb4841226a790f619d0eefb72 340 Hamap MF_00364 Beta-hexosaminidase [nagZ]. 3 334 48.015 T 29-03-2018 IPR022956 Beta-hexosaminidase, bacterial GO:0004563 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 MC49_RS17040 2ecc514fb4841226a790f619d0eefb72 340 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 235 252 - T 29-03-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 MC49_RS17040 2ecc514fb4841226a790f619d0eefb72 340 SUPERFAMILY SSF51445 2 307 1.68E-83 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily MC49_RS17040 2ecc514fb4841226a790f619d0eefb72 340 Gene3D G3DSA:3.20.20.300 1 338 2.0E-83 T 29-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MC49_RS11460 b67c8e32ebb4090fe67a347f11fee575 177 Gene3D G3DSA:2.60.40.1090 30 177 1.4E-30 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS11460 b67c8e32ebb4090fe67a347f11fee575 177 SUPERFAMILY SSF49401 31 177 1.24E-28 T 29-03-2018 IPR008966 Adhesion domain MC49_RS11460 b67c8e32ebb4090fe67a347f11fee575 177 Pfam PF00419 Fimbrial protein 33 176 2.1E-18 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS01680 c1714091aa40ca050251ad1142dfb1e1 347 SUPERFAMILY SSF53067 9 152 1.39E-36 T 29-03-2018 MC49_RS01680 c1714091aa40ca050251ad1142dfb1e1 347 Gene3D G3DSA:3.30.420.40 257 321 6.4E-8 T 29-03-2018 MC49_RS01680 c1714091aa40ca050251ad1142dfb1e1 347 Pfam PF06723 MreB/Mbl protein 11 338 8.6E-150 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MC49_RS01680 c1714091aa40ca050251ad1142dfb1e1 347 SUPERFAMILY SSF53067 153 342 2.39E-51 T 29-03-2018 MC49_RS01680 c1714091aa40ca050251ad1142dfb1e1 347 Gene3D G3DSA:3.30.420.40 8 163 1.8E-41 T 29-03-2018 MC49_RS01680 c1714091aa40ca050251ad1142dfb1e1 347 Gene3D G3DSA:3.90.640.10 199 256 1.1E-27 T 29-03-2018 MC49_RS01680 c1714091aa40ca050251ad1142dfb1e1 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 136 155 7.0E-65 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MC49_RS01680 c1714091aa40ca050251ad1142dfb1e1 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 72 95 7.0E-65 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MC49_RS01680 c1714091aa40ca050251ad1142dfb1e1 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 191 211 7.0E-65 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MC49_RS01680 c1714091aa40ca050251ad1142dfb1e1 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 52 70 7.0E-65 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MC49_RS01680 c1714091aa40ca050251ad1142dfb1e1 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 304 330 7.0E-65 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MC49_RS01680 c1714091aa40ca050251ad1142dfb1e1 347 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 9 339 3.9E-169 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MC49_RS01680 c1714091aa40ca050251ad1142dfb1e1 347 Gene3D G3DSA:3.30.420.40 164 198 2.9E-4 T 29-03-2018 MC49_RS06205 e4c6e2e64932aad8bdf58fbf1081857e 100 Pfam PF06411 HdeA/HdeB family 8 92 1.9E-20 T 29-03-2018 IPR010486 HNS-dependent expression A/B MC49_RS06205 e4c6e2e64932aad8bdf58fbf1081857e 100 ProDom PD070929 HDEB PRECURSOR SIGNAL EXPORTED PERIPLASMIC SECRETED ECS4389 10K-L SEQUENCING DIRECT 30 93 7.0E-15 T 29-03-2018 MC49_RS06205 e4c6e2e64932aad8bdf58fbf1081857e 100 Hamap MF_00947 Acid stress chaperone HdeB [hdeB]. 2 99 25.542 T 29-03-2018 IPR028623 HNS-dependent expression B GO:0009268|GO:0051082 MC49_RS06205 e4c6e2e64932aad8bdf58fbf1081857e 100 Gene3D G3DSA:1.10.890.10 25 97 1.7E-16 T 29-03-2018 MC49_RS12840 b2f85522c972ede80cff6539a4f46a60 216 SUPERFAMILY SSF46894 148 206 2.24E-16 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MC49_RS12840 b2f85522c972ede80cff6539a4f46a60 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 8.0E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS12840 b2f85522c972ede80cff6539a4f46a60 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 8.0E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS12840 b2f85522c972ede80cff6539a4f46a60 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 8.0E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS12840 b2f85522c972ede80cff6539a4f46a60 216 SUPERFAMILY SSF52172 3 135 4.55E-22 T 29-03-2018 IPR011006 CheY-like superfamily MC49_RS12840 b2f85522c972ede80cff6539a4f46a60 216 Gene3D G3DSA:1.10.10.10 132 210 7.8E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS12840 b2f85522c972ede80cff6539a4f46a60 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 204 3.3E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS12840 b2f85522c972ede80cff6539a4f46a60 216 SMART SM00421 148 205 8.5E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS12840 b2f85522c972ede80cff6539a4f46a60 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 165 192 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MC49_RS12840 b2f85522c972ede80cff6539a4f46a60 216 SMART SM00448 4 120 1.9E-14 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS12840 b2f85522c972ede80cff6539a4f46a60 216 Gene3D G3DSA:3.40.50.2300 3 131 1.3E-22 T 29-03-2018 MC49_RS12840 b2f85522c972ede80cff6539a4f46a60 216 Pfam PF00072 Response regulator receiver domain 6 120 6.4E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS12840 b2f85522c972ede80cff6539a4f46a60 216 Hamap MF_00981 Transcriptional regulatory protein RcsB [rcsB]. 1 214 50.771 T 29-03-2018 IPR030864 Transcriptional regulatory protein RcsB GO:0000160|GO:0006355 MC49_RS10385 47451ae69a9a2d34afbc36e21e6afcad 403 Gene3D G3DSA:3.90.1170.30 1 49 1.5E-14 T 29-03-2018 MC49_RS10385 47451ae69a9a2d34afbc36e21e6afcad 403 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 4 403 3.3E-188 T 29-03-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 MC49_RS10385 47451ae69a9a2d34afbc36e21e6afcad 403 SUPERFAMILY SSF52777 173 402 3.16E-89 T 29-03-2018 MC49_RS10385 47451ae69a9a2d34afbc36e21e6afcad 403 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 173 401 4.0E-82 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 MC49_RS10385 47451ae69a9a2d34afbc36e21e6afcad 403 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MC49_RS10385 47451ae69a9a2d34afbc36e21e6afcad 403 Pfam PF00364 Biotin-requiring enzyme 5 77 1.9E-18 T 29-03-2018 IPR000089 Biotin/lipoyl attachment MC49_RS10385 47451ae69a9a2d34afbc36e21e6afcad 403 Gene3D G3DSA:4.10.320.10 120 160 7.2E-19 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 MC49_RS10385 47451ae69a9a2d34afbc36e21e6afcad 403 SUPERFAMILY SSF51230 2 83 5.89E-24 T 29-03-2018 IPR011053 Single hybrid motif MC49_RS10385 47451ae69a9a2d34afbc36e21e6afcad 403 SUPERFAMILY SSF47005 107 150 6.28E-11 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 MC49_RS10385 47451ae69a9a2d34afbc36e21e6afcad 403 Pfam PF02817 e3 binding domain 113 146 7.0E-12 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 MC49_RS10385 47451ae69a9a2d34afbc36e21e6afcad 403 Gene3D G3DSA:3.40.47.10 81 119 0.093 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 MC49_RS10385 47451ae69a9a2d34afbc36e21e6afcad 403 Gene3D G3DSA:3.30.559.10 161 401 2.8E-91 T 29-03-2018 MC49_RS07165 26c5e0ca6c2ae5be97748270947b518b 208 SUPERFAMILY SSF54980 137 203 5.04E-13 T 29-03-2018 IPR035647 EF-G domain III/V-like MC49_RS07165 26c5e0ca6c2ae5be97748270947b518b 208 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 80 109 - T 29-03-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site MC49_RS07165 26c5e0ca6c2ae5be97748270947b518b 208 Pfam PF01205 Uncharacterized protein family UPF0029 18 125 4.6E-27 T 29-03-2018 IPR001498 Impact, N-terminal MC49_RS07165 26c5e0ca6c2ae5be97748270947b518b 208 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 1 200 4.9E-72 T 29-03-2018 IPR015796 Impact family, bacterial/archaeal MC49_RS07165 26c5e0ca6c2ae5be97748270947b518b 208 Pfam PF09186 Domain of unknown function (DUF1949) 141 195 7.5E-12 T 29-03-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal MC49_RS07165 26c5e0ca6c2ae5be97748270947b518b 208 SUPERFAMILY SSF54211 2 128 3.53E-42 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MC49_RS07165 26c5e0ca6c2ae5be97748270947b518b 208 Gene3D G3DSA:3.30.70.240 136 199 1.4E-13 T 29-03-2018 MC49_RS07165 26c5e0ca6c2ae5be97748270947b518b 208 Gene3D G3DSA:3.30.230.30 6 132 2.0E-36 T 29-03-2018 IPR001498 Impact, N-terminal MC49_RS12135 d6a94a9bb1cc2811d59453b54e924ebb 111 ProSitePatterns PS00814 Adrenodoxin family, iron-sulfur binding region signature. 42 52 - T 29-03-2018 IPR018298 Adrenodoxin, iron-sulphur binding site GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 MC49_RS12135 d6a94a9bb1cc2811d59453b54e924ebb 111 SUPERFAMILY SSF54292 4 109 4.3E-35 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MC49_RS12135 d6a94a9bb1cc2811d59453b54e924ebb 111 TIGRFAM TIGR02007 fdx_isc: ferredoxin, 2Fe-2S type, ISC system 2 111 1.5E-62 T 29-03-2018 IPR011536 Ferredoxin 2Fe-2S type, proteobacteria GO:0009055|GO:0051537 MC49_RS12135 d6a94a9bb1cc2811d59453b54e924ebb 111 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 14 91 1.3E-15 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MC49_RS12135 d6a94a9bb1cc2811d59453b54e924ebb 111 Gene3D G3DSA:3.10.20.30 4 111 2.0E-32 T 29-03-2018 IPR012675 Beta-grasp domain MC49_RS12135 d6a94a9bb1cc2811d59453b54e924ebb 111 PRINTS PR00355 Adrenodoxin signature 42 52 9.4E-10 T 29-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 MC49_RS12135 d6a94a9bb1cc2811d59453b54e924ebb 111 PRINTS PR00355 Adrenodoxin signature 83 91 9.4E-10 T 29-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 MC49_RS12135 d6a94a9bb1cc2811d59453b54e924ebb 111 PRINTS PR00355 Adrenodoxin signature 60 74 9.4E-10 T 29-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 MC49_RS04090 a4c88b78cc77a798eee091170624778b 130 Gene3D G3DSA:3.30.1490.10 74 129 8.4E-23 T 29-03-2018 MC49_RS04090 a4c88b78cc77a798eee091170624778b 130 Pfam PF00410 Ribosomal protein S8 5 129 9.0E-48 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04090 a4c88b78cc77a798eee091170624778b 130 Gene3D G3DSA:3.30.1370.30 1 66 4.5E-25 T 29-03-2018 MC49_RS04090 a4c88b78cc77a798eee091170624778b 130 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 130 31.41 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04090 a4c88b78cc77a798eee091170624778b 130 ProSitePatterns PS00053 Ribosomal protein S8 signature. 100 117 - T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04090 a4c88b78cc77a798eee091170624778b 130 SUPERFAMILY SSF56047 2 129 1.96E-45 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS11385 4a54c719fa5259aaae677c7bf14df8d3 346 Pfam PF04143 Sulphur transport 22 333 2.6E-80 T 29-03-2018 IPR007272 Sulphur transport domain MC49_RS09225 6653341596a674bf4f56cddcff6d7198 244 Gene3D G3DSA:3.30.420.10 1 190 9.0E-40 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MC49_RS09225 6653341596a674bf4f56cddcff6d7198 244 TIGRFAM TIGR01406 dnaQ_proteo: DNA polymerase III, epsilon subunit 7 243 6.7E-91 T 29-03-2018 IPR006309 DNA polymerase 3, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS09225 6653341596a674bf4f56cddcff6d7198 244 Pfam PF00929 Exonuclease 9 173 3.7E-37 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MC49_RS09225 6653341596a674bf4f56cddcff6d7198 244 SUPERFAMILY SSF53098 7 184 6.4E-52 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MC49_RS09225 6653341596a674bf4f56cddcff6d7198 244 SMART SM00479 7 184 5.5E-47 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MC49_RS09225 6653341596a674bf4f56cddcff6d7198 244 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 6 225 7.4E-87 T 29-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS07410 1bd2e008fcd208b0aa630775e20a088c 228 PIRSF PIRSF009467 2 228 9.2E-59 T 29-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 MC49_RS07410 1bd2e008fcd208b0aa630775e20a088c 228 Hamap MF_01385 Urease accessory protein UreF [ureF]. 5 228 23.116 T 29-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 MC49_RS07410 1bd2e008fcd208b0aa630775e20a088c 228 Pfam PF01730 UreF 37 185 3.8E-25 T 29-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 MC49_RS02815 e04d77afabf28d06b7252ae9f5d32f0c 260 Gene3D G3DSA:1.10.3720.10 5 260 1.9E-40 T 29-03-2018 MC49_RS02815 e04d77afabf28d06b7252ae9f5d32f0c 260 SUPERFAMILY SSF161098 3 255 2.06E-56 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS02815 e04d77afabf28d06b7252ae9f5d32f0c 260 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 75 247 4.6E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS16545 4551b556a4a5d8b4c40a370c081dc2c1 404 SUPERFAMILY SSF53383 6 401 4.03E-95 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS16545 4551b556a4a5d8b4c40a370c081dc2c1 404 Gene3D G3DSA:3.40.640.10 53 280 4.5E-49 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS16545 4551b556a4a5d8b4c40a370c081dc2c1 404 Pfam PF00155 Aminotransferase class I and II 60 394 6.8E-46 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MC49_RS16545 4551b556a4a5d8b4c40a370c081dc2c1 404 Gene3D G3DSA:3.90.1150.10 281 404 5.9E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS03530 75e4ed5d70a14c085d6e13a88989808e 206 SUPERFAMILY SSF54534 7 205 9.43E-56 T 29-03-2018 MC49_RS03530 75e4ed5d70a14c085d6e13a88989808e 206 Pfam PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 3 108 6.3E-23 T 29-03-2018 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 MC49_RS03530 75e4ed5d70a14c085d6e13a88989808e 206 Gene3D G3DSA:1.10.287.460 1 94 4.1E-20 T 29-03-2018 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 MC49_RS03530 75e4ed5d70a14c085d6e13a88989808e 206 Gene3D G3DSA:3.10.50.40 95 206 2.4E-42 T 29-03-2018 MC49_RS03530 75e4ed5d70a14c085d6e13a88989808e 206 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 117 203 9.2E-28 T 29-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain MC49_RS17405 0e930fb32b533f5e7ce58d0424319d6b 447 Pfam PF04055 Radical SAM superfamily 168 327 1.0E-11 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MC49_RS17405 0e930fb32b533f5e7ce58d0424319d6b 447 SMART SM00729 163 370 6.4E-15 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MC49_RS17405 0e930fb32b533f5e7ce58d0424319d6b 447 SUPERFAMILY SSF102114 163 362 8.76E-27 T 29-03-2018 MC49_RS17405 0e930fb32b533f5e7ce58d0424319d6b 447 Gene3D G3DSA:3.40.50.280 31 127 8.3E-6 T 29-03-2018 MC49_RS17405 0e930fb32b533f5e7ce58d0424319d6b 447 Gene3D G3DSA:3.20.20.70 150 437 2.6E-22 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS04140 095aa7513db3a5c86b387f58d261c436 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 29-03-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04140 095aa7513db3a5c86b387f58d261c436 92 Pfam PF00203 Ribosomal protein S19 3 83 5.2E-37 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04140 095aa7513db3a5c86b387f58d261c436 92 PIRSF PIRSF002144 1 92 1.5E-32 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04140 095aa7513db3a5c86b387f58d261c436 92 SUPERFAMILY SSF54570 3 84 4.71E-36 T 29-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04140 095aa7513db3a5c86b387f58d261c436 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 91 1.3E-46 T 29-03-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 MC49_RS04140 095aa7513db3a5c86b387f58d261c436 92 Gene3D G3DSA:3.30.860.10 1 92 1.6E-41 T 29-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04140 095aa7513db3a5c86b387f58d261c436 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 1.7E-25 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04140 095aa7513db3a5c86b387f58d261c436 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 1.7E-25 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04140 095aa7513db3a5c86b387f58d261c436 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 1.7E-25 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04140 095aa7513db3a5c86b387f58d261c436 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.844 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS01825 4df06d4998f049b87550336e9a013bd1 378 SUPERFAMILY SSF110738 1 375 4.58E-141 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 MC49_RS01825 4df06d4998f049b87550336e9a013bd1 378 Gene3D G3DSA:3.90.1510.10 42 276 1.5E-94 T 29-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 MC49_RS01825 4df06d4998f049b87550336e9a013bd1 378 PIRSF PIRSF006078 1 377 1.3E-134 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 MC49_RS01825 4df06d4998f049b87550336e9a013bd1 378 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 375 6.7E-161 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 MC49_RS01825 4df06d4998f049b87550336e9a013bd1 378 Pfam PF02595 Glycerate kinase family 3 373 2.9E-148 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 MC49_RS04450 805d6298b0327298dfa3e90ad29f180d 573 Gene3D G3DSA:3.40.50.970 1 188 2.5E-40 T 29-03-2018 MC49_RS04450 805d6298b0327298dfa3e90ad29f180d 573 SUPERFAMILY SSF52467 182 350 1.89E-44 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MC49_RS04450 805d6298b0327298dfa3e90ad29f180d 573 SUPERFAMILY SSF52518 358 558 6.82E-59 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MC49_RS04450 805d6298b0327298dfa3e90ad29f180d 573 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 193 318 1.2E-31 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MC49_RS04450 805d6298b0327298dfa3e90ad29f180d 573 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 170 3.1E-40 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MC49_RS04450 805d6298b0327298dfa3e90ad29f180d 573 Gene3D G3DSA:3.40.50.1220 189 336 2.0E-34 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MC49_RS04450 805d6298b0327298dfa3e90ad29f180d 573 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 380 526 2.4E-39 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MC49_RS04450 805d6298b0327298dfa3e90ad29f180d 573 SUPERFAMILY SSF52518 1 177 3.78E-42 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MC49_RS04450 805d6298b0327298dfa3e90ad29f180d 573 Gene3D G3DSA:3.40.50.970 337 536 8.0E-43 T 29-03-2018 MC49_RS14420 b06bfc18ce55f8cdcb6b5c9c274b509f 342 SMART SM00354 5 75 6.8E-29 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MC49_RS14420 b06bfc18ce55f8cdcb6b5c9c274b509f 342 SUPERFAMILY SSF53822 63 331 3.2E-55 T 29-03-2018 IPR028082 Periplasmic binding protein-like I MC49_RS14420 b06bfc18ce55f8cdcb6b5c9c274b509f 342 Gene3D G3DSA:3.40.50.2300 60 179 7.2E-32 T 29-03-2018 MC49_RS14420 b06bfc18ce55f8cdcb6b5c9c274b509f 342 SUPERFAMILY SSF47413 4 62 9.57E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS14420 b06bfc18ce55f8cdcb6b5c9c274b509f 342 Gene3D G3DSA:1.10.260.40 6 59 1.7E-20 T 29-03-2018 MC49_RS14420 b06bfc18ce55f8cdcb6b5c9c274b509f 342 ProSitePatterns PS00356 LacI-type HTH domain signature. 8 26 - T 29-03-2018 MC49_RS14420 b06bfc18ce55f8cdcb6b5c9c274b509f 342 Gene3D G3DSA:3.40.50.2300 180 326 2.2E-31 T 29-03-2018 MC49_RS14420 b06bfc18ce55f8cdcb6b5c9c274b509f 342 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 52 3.0E-18 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MC49_RS14420 b06bfc18ce55f8cdcb6b5c9c274b509f 342 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 64 324 3.8E-47 T 29-03-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain MC49_RS13015 344e0edf6626c8f07e579aee54411853 144 PIRSF PIRSF029598 2 140 3.7E-39 T 29-03-2018 IPR009315 Phosphate-starvation-induced PsiE GO:0016021|GO:0016036 MC49_RS13015 344e0edf6626c8f07e579aee54411853 144 Pfam PF06146 Phosphate-starvation-inducible E 60 121 1.8E-11 T 29-03-2018 IPR020948 Phosphate-starvation-induced PsiE-like MC49_RS08585 4f01f3b6b5eb55068ee8bfd5a574146d 281 SUPERFAMILY SSF53067 33 130 4.43E-8 T 29-03-2018 MC49_RS08585 4f01f3b6b5eb55068ee8bfd5a574146d 281 Gene3D G3DSA:3.30.420.40 147 255 1.0E-15 T 29-03-2018 MC49_RS08585 4f01f3b6b5eb55068ee8bfd5a574146d 281 SUPERFAMILY SSF53067 142 271 1.08E-20 T 29-03-2018 MC49_RS08585 4f01f3b6b5eb55068ee8bfd5a574146d 281 Pfam PF14450 Cell division protein FtsA 143 210 5.5E-8 T 29-03-2018 MC49_RS08585 4f01f3b6b5eb55068ee8bfd5a574146d 281 Gene3D G3DSA:3.30.420.40 4 146 1.9E-15 T 29-03-2018 MC49_RS08585 4f01f3b6b5eb55068ee8bfd5a574146d 281 TIGRFAM TIGR02529 EutJ: ethanolamine utilization protein EutJ family protein 36 269 1.1E-95 T 29-03-2018 IPR013366 Ethanolamine utilisation EutJ MC49_RS17340 06ce52319bfada6d586d36f15fc01672 225 Pfam PF07077 Protein of unknown function (DUF1345) 45 216 9.4E-51 T 29-03-2018 IPR009781 Protein of unknown function DUF1345 MC49_RS01530 e69f83fad852d3dda06011f824ed1cb3 209 Pfam PF05494 MlaC protein 32 197 1.4E-53 T 29-03-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC MC49_RS01530 e69f83fad852d3dda06011f824ed1cb3 209 Gene3D G3DSA:3.10.450.50 25 73 1.6E-6 T 29-03-2018 MC49_RS01530 e69f83fad852d3dda06011f824ed1cb3 209 Gene3D G3DSA:3.10.450.50 74 171 2.5E-21 T 29-03-2018 MC49_RS01530 e69f83fad852d3dda06011f824ed1cb3 209 PIRSF PIRSF004649 1 209 6.5E-61 T 29-03-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC MC49_RS07390 a86079af1392b7b058b948b229c23f8c 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 100 1.8E-42 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MC49_RS07390 a86079af1392b7b058b948b229c23f8c 100 Pfam PF00547 Urease, gamma subunit 1 99 8.8E-43 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MC49_RS07390 a86079af1392b7b058b948b229c23f8c 100 Gene3D G3DSA:3.30.280.10 2 99 6.9E-42 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MC49_RS07390 a86079af1392b7b058b948b229c23f8c 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 6.0E-39 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MC49_RS07390 a86079af1392b7b058b948b229c23f8c 100 PIRSF PIRSF001223 1 100 3.4E-48 T 29-03-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MC49_RS07390 a86079af1392b7b058b948b229c23f8c 100 SUPERFAMILY SSF54111 1 99 4.58E-41 T 29-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MC49_RS07390 a86079af1392b7b058b948b229c23f8c 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 32.597 T 29-03-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MC49_RS09365 435bf7bc892f678cd3eb54714cd19a1d 225 Gene3D G3DSA:3.30.240.20 157 212 2.2E-12 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain MC49_RS09365 435bf7bc892f678cd3eb54714cd19a1d 225 Pfam PF04239 Protein of unknown function (DUF421) 91 191 2.6E-23 T 29-03-2018 IPR007353 Protein of unknown function DUF421 MC49_RS09365 435bf7bc892f678cd3eb54714cd19a1d 225 Gene3D G3DSA:3.30.240.20 83 153 4.7E-16 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain MC49_RS06515 c7684595adcc3c67a876efc47027aa2c 356 SUPERFAMILY SSF53850 43 348 7.39E-48 T 29-03-2018 MC49_RS06515 c7684595adcc3c67a876efc47027aa2c 356 Gene3D G3DSA:3.40.190.10 179 328 3.8E-18 T 29-03-2018 MC49_RS06515 c7684595adcc3c67a876efc47027aa2c 356 Pfam PF13343 Bacterial extracellular solute-binding protein 91 325 4.1E-34 T 29-03-2018 MC49_RS06515 c7684595adcc3c67a876efc47027aa2c 356 Gene3D G3DSA:3.40.190.10 7 178 3.6E-17 T 29-03-2018 MC49_RS09645 61dd7c5eb3224c2583c59183b46d153a 217 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 75 92 9.1E-9 T 29-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial MC49_RS09645 61dd7c5eb3224c2583c59183b46d153a 217 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 155 170 9.1E-9 T 29-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial MC49_RS09645 61dd7c5eb3224c2583c59183b46d153a 217 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 132 142 9.1E-9 T 29-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial MC49_RS09645 61dd7c5eb3224c2583c59183b46d153a 217 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 143 154 9.1E-9 T 29-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial MC49_RS09645 61dd7c5eb3224c2583c59183b46d153a 217 Pfam PF01478 Type IV leader peptidase family 67 173 2.3E-18 T 29-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 MC49_RS04605 e7c9d27d5b856dd08735f87dc5a3767f 836 Pfam PF13954 PapC N-terminal domain 48 180 2.3E-23 T 29-03-2018 IPR025885 PapC, N-terminal domain GO:0005515 MC49_RS04605 e7c9d27d5b856dd08735f87dc5a3767f 836 Pfam PF00577 Outer membrane usher protein 195 744 2.9E-141 T 29-03-2018 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 MC49_RS04605 e7c9d27d5b856dd08735f87dc5a3767f 836 SUPERFAMILY SSF141729 61 172 1.7E-15 T 29-03-2018 MC49_RS04605 e7c9d27d5b856dd08735f87dc5a3767f 836 Pfam PF13953 PapC C-terminal domain 753 816 3.5E-10 T 29-03-2018 IPR025949 PapC-like, C-terminal domain MC49_RS13355 181ebd8cf4a981f94568dcdd841bc3f8 144 SUPERFAMILY SSF88659 69 131 5.42E-6 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MC49_RS13355 181ebd8cf4a981f94568dcdd841bc3f8 144 Gene3D G3DSA:1.10.10.10 48 122 5.4E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS13355 181ebd8cf4a981f94568dcdd841bc3f8 144 Pfam PF06530 Phage antitermination protein Q 4 125 1.9E-33 T 29-03-2018 IPR010534 Bacteriophage 933W, GpQ GO:0003677|GO:0060567 MC49_RS14460 5e002fb0b509d9d7c6848c3bc4e681fc 79 Pfam PF14891 Effector protein 11 78 1.2E-9 T 29-03-2018 IPR028208 Effector protein NleD-like MC49_RS14460 5e002fb0b509d9d7c6848c3bc4e681fc 79 Gene3D G3DSA:3.90.1240.10 6 78 1.5E-5 T 29-03-2018 MC49_RS08665 b081bcacce5a7f39637d92b7a9af01fa 340 Pfam PF01145 SPFH domain / Band 7 family 15 184 3.1E-10 T 29-03-2018 IPR001107 Band 7 domain MC49_RS08665 b081bcacce5a7f39637d92b7a9af01fa 340 SUPERFAMILY SSF117892 56 181 1.83E-6 T 29-03-2018 IPR001107 Band 7 domain MC49_RS10190 fb79a3302ae804b89ea19e715033176a 242 Pfam PF13462 Thioredoxin 82 235 3.2E-22 T 29-03-2018 IPR012336 Thioredoxin-like fold MC49_RS10190 fb79a3302ae804b89ea19e715033176a 242 SUPERFAMILY SSF52833 71 235 7.75E-38 T 29-03-2018 IPR012336 Thioredoxin-like fold MC49_RS10190 fb79a3302ae804b89ea19e715033176a 242 Gene3D G3DSA:3.40.30.10 72 242 5.9E-36 T 29-03-2018 MC49_RS10190 fb79a3302ae804b89ea19e715033176a 242 ProSitePatterns PS00194 Thioredoxin family active site. 95 113 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MC49_RS18830 6a17519948ce632c9928b3438fe5efd1 502 SMART SM00382 284 479 0.82 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS18830 6a17519948ce632c9928b3438fe5efd1 502 SMART SM00382 34 221 8.2E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS18830 6a17519948ce632c9928b3438fe5efd1 502 ProSitePatterns PS00211 ABC transporters family signature. 403 417 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS18830 6a17519948ce632c9928b3438fe5efd1 502 SUPERFAMILY SSF52540 8 232 2.76E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS18830 6a17519948ce632c9928b3438fe5efd1 502 Gene3D G3DSA:3.40.50.300 262 500 3.3E-34 T 29-03-2018 MC49_RS18830 6a17519948ce632c9928b3438fe5efd1 502 SUPERFAMILY SSF52540 250 488 5.99E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS18830 6a17519948ce632c9928b3438fe5efd1 502 Pfam PF00005 ABC transporter 25 174 2.8E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS18830 6a17519948ce632c9928b3438fe5efd1 502 Pfam PF00005 ABC transporter 276 430 1.6E-17 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS18830 6a17519948ce632c9928b3438fe5efd1 502 Gene3D G3DSA:3.40.50.300 1 240 3.1E-51 T 29-03-2018 MC49_RS15995 99521acb5174b1db4c2a13c3dcf4eb36 226 Pfam PF01464 Transglycosylase SLT domain 62 187 2.8E-26 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 MC49_RS15995 99521acb5174b1db4c2a13c3dcf4eb36 226 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 79 107 - T 29-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 MC49_RS15995 99521acb5174b1db4c2a13c3dcf4eb36 226 SUPERFAMILY SSF53955 57 223 4.5E-28 T 29-03-2018 IPR023346 Lysozyme-like domain MC49_RS15995 99521acb5174b1db4c2a13c3dcf4eb36 226 Gene3D G3DSA:1.10.530.10 50 222 7.4E-29 T 29-03-2018 MC49_RS14035 57937b895d8528d63aa8bdfc2b151496 132 Gene3D G3DSA:1.20.120.550 1 130 1.5E-20 T 29-03-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain MC49_RS14035 57937b895d8528d63aa8bdfc2b151496 132 Pfam PF01124 MAPEG family 4 120 3.7E-24 T 29-03-2018 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein MC49_RS14035 57937b895d8528d63aa8bdfc2b151496 132 SUPERFAMILY SSF161084 4 126 1.83E-28 T 29-03-2018 MC49_RS00805 7001b9ccf793eda27228c84ccc59344b 453 Gene3D G3DSA:1.20.1250.20 203 396 3.6E-16 T 29-03-2018 MC49_RS00805 7001b9ccf793eda27228c84ccc59344b 453 SUPERFAMILY SSF103473 1 391 1.96E-65 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS00805 7001b9ccf793eda27228c84ccc59344b 453 Pfam PF07690 Major Facilitator Superfamily 20 354 9.6E-45 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS00805 7001b9ccf793eda27228c84ccc59344b 453 Gene3D G3DSA:1.20.1250.20 3 200 1.4E-34 T 29-03-2018 MC49_RS03120 d64c115b460389aee1d143871c9f5df6 89 SMART SM00530 14 69 4.0E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS03120 d64c115b460389aee1d143871c9f5df6 89 Gene3D G3DSA:1.10.260.40 1 86 2.9E-18 T 29-03-2018 MC49_RS03120 d64c115b460389aee1d143871c9f5df6 89 SUPERFAMILY SSF47413 8 74 1.69E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS03120 d64c115b460389aee1d143871c9f5df6 89 Pfam PF01381 Helix-turn-helix 15 69 5.3E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS14520 999e5930cee4713d73b71e7c33f266f8 303 Pfam PF01497 Periplasmic binding protein 40 275 1.2E-33 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 MC49_RS14520 999e5930cee4713d73b71e7c33f266f8 303 Gene3D G3DSA:3.40.50.1980 132 302 4.4E-29 T 29-03-2018 MC49_RS14520 999e5930cee4713d73b71e7c33f266f8 303 Gene3D G3DSA:3.40.50.1980 21 131 6.0E-24 T 29-03-2018 MC49_RS14520 999e5930cee4713d73b71e7c33f266f8 303 SUPERFAMILY SSF53807 30 295 6.28E-55 T 29-03-2018 MC49_RS16930 3651f2ad3a26cf16687c14282e5f9f01 229 Gene3D G3DSA:3.30.70.580 36 118 1.1E-14 T 29-03-2018 MC49_RS16930 3651f2ad3a26cf16687c14282e5f9f01 229 Gene3D G3DSA:3.30.70.1560 119 196 7.4E-24 T 29-03-2018 MC49_RS16930 3651f2ad3a26cf16687c14282e5f9f01 229 Pfam PF00849 RNA pseudouridylate synthase 39 184 2.8E-14 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS16930 3651f2ad3a26cf16687c14282e5f9f01 229 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 43 214 3.0E-57 T 29-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 MC49_RS16930 3651f2ad3a26cf16687c14282e5f9f01 229 SUPERFAMILY SSF55120 39 214 3.84E-43 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS16930 3651f2ad3a26cf16687c14282e5f9f01 229 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 74 88 - T 29-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 MC49_RS14965 b21078edc219b7f3cf0f5c54c94fe6c0 254 Gene3D G3DSA:2.30.260.10 123 252 3.7E-22 T 29-03-2018 MC49_RS14965 b21078edc219b7f3cf0f5c54c94fe6c0 254 Gene3D G3DSA:1.10.3670.10 31 122 3.6E-28 T 29-03-2018 MC49_RS14965 b21078edc219b7f3cf0f5c54c94fe6c0 254 Pfam PF07313 Protein of unknown function (DUF1460) 47 243 7.1E-67 T 29-03-2018 IPR010846 Protein of unknown function DUF1460 MC49_RS14965 b21078edc219b7f3cf0f5c54c94fe6c0 254 SUPERFAMILY SSF54001 42 250 4.51E-69 T 29-03-2018 MC49_RS11420 c72fef9bebe0a26a88c0c98ead889c6e 105 SMART SM00530 22 77 1.2E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS11420 c72fef9bebe0a26a88c0c98ead889c6e 105 Pfam PF01381 Helix-turn-helix 23 75 1.7E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS11420 c72fef9bebe0a26a88c0c98ead889c6e 105 Gene3D G3DSA:1.10.3100.10 13 103 4.9E-14 T 29-03-2018 IPR027910 YdiL-like domain MC49_RS11420 c72fef9bebe0a26a88c0c98ead889c6e 105 SUPERFAMILY SSF47413 11 78 7.6E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS09170 cf53685dee2efc2469d95ad96f3c066f 373 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 86 214 4.9E-10 T 29-03-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MC49_RS09170 cf53685dee2efc2469d95ad96f3c066f 373 SUPERFAMILY SSF55931 67 361 3.92E-21 T 29-03-2018 MC49_RS09170 cf53685dee2efc2469d95ad96f3c066f 373 SUPERFAMILY SSF55931 4 20 3.92E-21 T 29-03-2018 MC49_RS14620 47ce88d58be203012670e33cfd64b078 247 Pfam PF13803 Domain of unknown function (DUF4184) 1 237 1.9E-47 T 29-03-2018 IPR025238 Protein of unknown function DUF4184 MC49_RS11505 29bbd311193142a4dcf9801970663e63 122 SMART SM00422 3 71 4.9E-23 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MC49_RS11505 29bbd311193142a4dcf9801970663e63 122 Pfam PF13411 MerR HTH family regulatory protein 3 68 7.7E-20 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MC49_RS11505 29bbd311193142a4dcf9801970663e63 122 Gene3D G3DSA:1.10.1660.10 1 56 5.9E-22 T 29-03-2018 MC49_RS11505 29bbd311193142a4dcf9801970663e63 122 SUPERFAMILY SSF46955 3 116 5.49E-31 T 29-03-2018 IPR009061 Putative DNA-binding domain MC49_RS11505 29bbd311193142a4dcf9801970663e63 122 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 8.5E-7 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MC49_RS11505 29bbd311193142a4dcf9801970663e63 122 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 8.5E-7 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MC49_RS11505 29bbd311193142a4dcf9801970663e63 122 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 38 58 8.5E-7 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MC49_RS11505 29bbd311193142a4dcf9801970663e63 122 Gene3D G3DSA:1.10.1660.10 57 121 7.0E-15 T 29-03-2018 MC49_RS09525 1a8e2a13a47a6e415563962c3b39c5d3 496 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 38 443 2.9E-68 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 MC49_RS09525 1a8e2a13a47a6e415563962c3b39c5d3 496 Pfam PF00474 Sodium:solute symporter family 38 442 3.0E-43 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 MC49_RS16995 3ccd2cc7620137249a303a9bfae8e6f4 288 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 47 277 57.914 T 29-03-2018 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 Reactome: R-HSA-2151201 MC49_RS16995 3ccd2cc7620137249a303a9bfae8e6f4 288 SUPERFAMILY SSF52467 47 276 5.03E-75 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MC49_RS16995 3ccd2cc7620137249a303a9bfae8e6f4 288 Pfam PF02146 Sir2 family 54 227 2.4E-51 T 29-03-2018 IPR003000 Sirtuin family GO:0070403 MC49_RS16995 3ccd2cc7620137249a303a9bfae8e6f4 288 Gene3D G3DSA:3.40.50.1220 41 285 4.4E-55 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MC49_RS18275 e2204e2da80907a65d3bee41494a6b0d 207 ProSitePatterns PS00211 ABC transporters family signature. 124 138 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS18275 e2204e2da80907a65d3bee41494a6b0d 207 SUPERFAMILY SSF52540 5 202 1.11E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS18275 e2204e2da80907a65d3bee41494a6b0d 207 Gene3D G3DSA:3.40.50.300 2 206 4.4E-52 T 29-03-2018 MC49_RS18275 e2204e2da80907a65d3bee41494a6b0d 207 Pfam PF00005 ABC transporter 12 151 5.1E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS18275 e2204e2da80907a65d3bee41494a6b0d 207 SMART SM00382 21 200 9.1E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS01385 f36f4897ac54fe77c33c3744a5cc57ac 232 Pfam PF02678 Pirin 12 119 7.7E-12 T 29-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 MC49_RS01385 f36f4897ac54fe77c33c3744a5cc57ac 232 SUPERFAMILY SSF51182 1 229 8.48E-35 T 29-03-2018 IPR011051 RmlC-like cupin domain MC49_RS01385 f36f4897ac54fe77c33c3744a5cc57ac 232 Gene3D G3DSA:2.60.120.10 12 134 1.9E-16 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MC49_RS01385 f36f4897ac54fe77c33c3744a5cc57ac 232 Gene3D G3DSA:2.60.120.10 135 231 2.4E-18 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MC49_RS06295 6f89a920163be1e2ac615585bfb00955 328 SUPERFAMILY SSF53474 24 317 8.96E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS06295 6f89a920163be1e2ac615585bfb00955 328 Pfam PF00561 alpha/beta hydrolase fold 60 299 9.0E-19 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MC49_RS06295 6f89a920163be1e2ac615585bfb00955 328 Gene3D G3DSA:3.40.50.1820 35 322 8.0E-29 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS06295 6f89a920163be1e2ac615585bfb00955 328 PIRSF PIRSF005211 1 328 7.7E-106 T 29-03-2018 IPR012020 AB hydrolase 4 family MC49_RS06295 6f89a920163be1e2ac615585bfb00955 328 ProSitePatterns PS01133 Uncharacterized protein family UPF0017 signature. 226 267 - T 29-03-2018 IPR000952 AB hydrolase 4, conserved site MC49_RS14750 f7bb9c906d3b40b9a99f5fc34f2b3302 265 Gene3D G3DSA:1.10.260.40 1 106 1.1E-12 T 29-03-2018 MC49_RS14750 f7bb9c906d3b40b9a99f5fc34f2b3302 265 SMART SM00530 14 86 1.6E-4 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS14750 f7bb9c906d3b40b9a99f5fc34f2b3302 265 Pfam PF13560 Helix-turn-helix domain 10 89 3.5E-15 T 29-03-2018 MC49_RS18875 d8ec3ba4c55c284fe7b4cddc7357d4e4 183 Pfam PF10263 SprT-like family 37 118 2.6E-15 T 29-03-2018 IPR006640 SprT-like MC49_RS18875 d8ec3ba4c55c284fe7b4cddc7357d4e4 183 SMART SM00731 16 166 7.1E-54 T 29-03-2018 IPR006640 SprT-like MC49_RS18875 d8ec3ba4c55c284fe7b4cddc7357d4e4 183 Pfam PF17283 SprT-like zinc ribbon domain 126 164 1.5E-9 T 29-03-2018 IPR035240 SprT-like, zinc ribbon domain MC49_RS18875 d8ec3ba4c55c284fe7b4cddc7357d4e4 183 Hamap MF_00746 Protein SprT [sprT]. 12 166 39.317 T 29-03-2018 IPR023483 Uncharacterised protein family SprT MC49_RS15120 98decb63b0f71e8a4a5916e76b8fc859 350 Gene3D G3DSA:3.90.226.10 125 308 9.6E-33 T 29-03-2018 MC49_RS15120 98decb63b0f71e8a4a5916e76b8fc859 350 SUPERFAMILY SSF52096 240 295 4.97E-31 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MC49_RS15120 98decb63b0f71e8a4a5916e76b8fc859 350 SUPERFAMILY SSF52096 97 209 4.97E-31 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MC49_RS15120 98decb63b0f71e8a4a5916e76b8fc859 350 Pfam PF08496 Peptidase family S49 N-terminal 2 158 1.1E-57 T 29-03-2018 IPR013703 Peptidase S49, N-terminal proteobacteria GO:0004252|GO:0005886 MC49_RS15120 98decb63b0f71e8a4a5916e76b8fc859 350 Pfam PF01343 Peptidase family S49 161 303 3.9E-48 T 29-03-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 MC49_RS00825 b9dccdff9de2dec9235cfb89df30b525 593 Pfam PF13687 Domain of unknown function (DUF4153) 156 388 2.6E-8 T 29-03-2018 IPR025291 Protein of unknown function DUF4153 MC49_RS00385 ab541b59e08a87aaeac8c1586c35e10a 81 Gene3D G3DSA:2.30.130.30 2 79 3.8E-15 T 29-03-2018 MC49_RS18155 c4c44dd5c686159e999be4308cdc2955 110 SUPERFAMILY SSF50249 8 109 2.08E-29 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS18155 c4c44dd5c686159e999be4308cdc2955 110 Gene3D G3DSA:2.40.50.140 7 110 3.9E-30 T 29-03-2018 MC49_RS18155 c4c44dd5c686159e999be4308cdc2955 110 Pfam PF01588 Putative tRNA binding domain 14 107 6.8E-29 T 29-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 MC49_RS19160 23f7cb55d6d637440b76f026cd1578ee 214 Gene3D G3DSA:2.40.128.20 27 214 2.0E-70 T 29-03-2018 IPR012674 Calycin MC49_RS19160 23f7cb55d6d637440b76f026cd1578ee 214 SUPERFAMILY SSF50814 29 214 1.17E-76 T 29-03-2018 IPR012674 Calycin MC49_RS19160 23f7cb55d6d637440b76f026cd1578ee 214 Pfam PF09223 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment 35 214 4.2E-86 T 29-03-2018 IPR015304 ZinT domain GO:0008270 MC49_RS01080 a8dc8bbb671160a0f40c1cc4cd2cb587 355 Pfam PF00437 Type II/IV secretion system protein 32 299 1.7E-79 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 MC49_RS01080 a8dc8bbb671160a0f40c1cc4cd2cb587 355 SUPERFAMILY SSF52540 16 293 2.85E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS01080 a8dc8bbb671160a0f40c1cc4cd2cb587 355 Gene3D G3DSA:3.30.450.90 24 130 1.2E-18 T 29-03-2018 MC49_RS01080 a8dc8bbb671160a0f40c1cc4cd2cb587 355 TIGRFAM TIGR02782 TrbB_P: P-type conjugative transfer ATPase TrbB 20 320 2.5E-122 T 29-03-2018 IPR014149 Conjugative transfer, TrbB GO:0000746|GO:0005737 MC49_RS01080 a8dc8bbb671160a0f40c1cc4cd2cb587 355 Gene3D G3DSA:3.40.50.300 147 313 1.7E-12 T 29-03-2018 MC49_RS12290 c64081623d08aa9ce9f858e5cc1ebb9a 295 Pfam PF12833 Helix-turn-helix domain 213 291 6.9E-23 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MC49_RS12290 c64081623d08aa9ce9f858e5cc1ebb9a 295 SMART SM00342 207 290 6.9E-25 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MC49_RS12290 c64081623d08aa9ce9f858e5cc1ebb9a 295 SUPERFAMILY SSF46689 243 293 1.03E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS12290 c64081623d08aa9ce9f858e5cc1ebb9a 295 Gene3D G3DSA:1.10.10.60 247 293 9.9E-12 T 29-03-2018 MC49_RS12290 c64081623d08aa9ce9f858e5cc1ebb9a 295 Gene3D G3DSA:1.10.10.60 178 246 4.0E-14 T 29-03-2018 MC49_RS12290 c64081623d08aa9ce9f858e5cc1ebb9a 295 SUPERFAMILY SSF46689 191 240 1.19E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS12290 c64081623d08aa9ce9f858e5cc1ebb9a 295 Pfam PF06719 AraC-type transcriptional regulator N-terminus 29 178 2.4E-40 T 29-03-2018 IPR009594 Transcription regulator HTH, AraC, N-terminal MC49_RS13565 bf30d31dbb915265d79abce8fabee1b3 214 Gene3D G3DSA:3.40.50.850 1 208 7.8E-34 T 29-03-2018 MC49_RS13565 bf30d31dbb915265d79abce8fabee1b3 214 Pfam PF00857 Isochorismatase family 12 165 1.1E-24 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 MC49_RS13565 bf30d31dbb915265d79abce8fabee1b3 214 SUPERFAMILY SSF52499 2 204 5.76E-49 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 MC49_RS03265 d251a1697f2812c53001925354b128c8 399 Gene3D G3DSA:1.20.1250.20 2 201 8.7E-12 T 29-03-2018 MC49_RS03265 d251a1697f2812c53001925354b128c8 399 SUPERFAMILY SSF103473 17 384 1.83E-29 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS03265 d251a1697f2812c53001925354b128c8 399 Gene3D G3DSA:1.20.1250.20 205 398 1.9E-11 T 29-03-2018 MC49_RS03265 d251a1697f2812c53001925354b128c8 399 Pfam PF07690 Major Facilitator Superfamily 20 332 5.0E-16 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS15385 7775501931eb359a9f5462860c58b19d 287 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 7.1E-14 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS15385 7775501931eb359a9f5462860c58b19d 287 SUPERFAMILY SSF46785 5 79 9.25E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS15385 7775501931eb359a9f5462860c58b19d 287 Gene3D G3DSA:1.10.10.10 4 84 2.2E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS00980 acedd73c9fa7e88956a69408cc7f08c3 367 Gene3D G3DSA:3.40.50.300 173 312 3.7E-22 T 29-03-2018 MC49_RS00980 acedd73c9fa7e88956a69408cc7f08c3 367 TIGRFAM TIGR00073 hypB: hydrogenase accessory protein HypB 145 355 2.5E-93 T 29-03-2018 IPR004392 Hydrogenase accessory protein HypB GO:0006461|GO:0016151 MC49_RS00980 acedd73c9fa7e88956a69408cc7f08c3 367 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 174 335 8.8E-35 T 29-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain MC49_RS00980 acedd73c9fa7e88956a69408cc7f08c3 367 SUPERFAMILY SSF52540 151 357 8.84E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS00980 acedd73c9fa7e88956a69408cc7f08c3 367 Gene3D G3DSA:3.40.50.300 313 365 6.1E-6 T 29-03-2018 MC49_RS14285 19ef5f14c646b0bbb4bec33570b46e80 246 Pfam PF00005 ABC transporter 18 153 3.5E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS14285 19ef5f14c646b0bbb4bec33570b46e80 246 Gene3D G3DSA:3.40.50.300 1 224 1.4E-51 T 29-03-2018 MC49_RS14285 19ef5f14c646b0bbb4bec33570b46e80 246 SUPERFAMILY SSF52540 2 216 2.28E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS14285 19ef5f14c646b0bbb4bec33570b46e80 246 ProSitePatterns PS00211 ABC transporters family signature. 125 139 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS14285 19ef5f14c646b0bbb4bec33570b46e80 246 SMART SM00382 26 202 3.4E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS16705 75fbe6b31ca45c2a2a6ebe742b3f919d 266 Pfam PF01925 Sulfite exporter TauE/SafE 14 249 3.2E-39 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MC49_RS03505 6dd388d2f990fb1eeb831b6edbbcae5f 580 Pfam PF17243 POTRA domain TamA domain 1 26 100 2.3E-16 T 29-03-2018 IPR035243 TamA, POTRA domain 1 MC49_RS03505 6dd388d2f990fb1eeb831b6edbbcae5f 580 Pfam PF01103 Surface antigen 284 577 5.4E-34 T 29-03-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 MC49_RS03505 6dd388d2f990fb1eeb831b6edbbcae5f 580 Gene3D G3DSA:3.10.20.310 102 189 2.8E-13 T 29-03-2018 MC49_RS03505 6dd388d2f990fb1eeb831b6edbbcae5f 580 Pfam PF07244 Surface antigen variable number repeat 190 246 4.3E-7 T 29-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 MC49_RS03505 6dd388d2f990fb1eeb831b6edbbcae5f 580 Gene3D G3DSA:2.40.160.50 221 579 2.4E-56 T 29-03-2018 MC49_RS15165 ac4093d1e06450c6317c7c3d5efe433c 455 SUPERFAMILY SSF51366 13 255 6.31E-80 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MC49_RS15165 ac4093d1e06450c6317c7c3d5efe433c 455 SUPERFAMILY SSF51366 258 450 1.46E-56 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MC49_RS15165 ac4093d1e06450c6317c7c3d5efe433c 455 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 259 453 30.604 T 29-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 MC49_RS15165 ac4093d1e06450c6317c7c3d5efe433c 455 Pfam PF00218 Indole-3-glycerol phosphate synthase 6 253 1.8E-92 T 29-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 MC49_RS15165 ac4093d1e06450c6317c7c3d5efe433c 455 Gene3D G3DSA:3.20.20.70 5 256 1.3E-63 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS15165 ac4093d1e06450c6317c7c3d5efe433c 455 Gene3D G3DSA:3.20.20.70 258 454 8.9E-56 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS15165 ac4093d1e06450c6317c7c3d5efe433c 455 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 4 255 34.015 T 29-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 MC49_RS15165 ac4093d1e06450c6317c7c3d5efe433c 455 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 51 69 - T 29-03-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 MC49_RS15165 ac4093d1e06450c6317c7c3d5efe433c 455 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 259 448 3.4E-51 T 29-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 MC49_RS01605 a8caab8a514fa055e7796113baf5e199 90 SUPERFAMILY SSF55594 4 90 4.58E-23 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like MC49_RS01605 a8caab8a514fa055e7796113baf5e199 90 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 14 21 - T 29-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site MC49_RS01605 a8caab8a514fa055e7796113baf5e199 90 PRINTS PR00107 Phosphocarrier protein signature 55 72 3.7E-8 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like MC49_RS01605 a8caab8a514fa055e7796113baf5e199 90 PRINTS PR00107 Phosphocarrier protein signature 40 55 3.7E-8 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like MC49_RS01605 a8caab8a514fa055e7796113baf5e199 90 PRINTS PR00107 Phosphocarrier protein signature 14 30 3.7E-8 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like MC49_RS01605 a8caab8a514fa055e7796113baf5e199 90 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 5 83 1.1E-19 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like MC49_RS01605 a8caab8a514fa055e7796113baf5e199 90 Pfam PF00381 PTS HPr component phosphorylation site 6 84 1.8E-22 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like MC49_RS01605 a8caab8a514fa055e7796113baf5e199 90 Gene3D G3DSA:3.30.1340.10 2 89 1.1E-21 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like MC49_RS02335 78e20f7a2969a77ca539c1f9647d11ec 524 Gene3D G3DSA:3.40.190.10 149 285 9.6E-31 T 29-03-2018 MC49_RS02335 78e20f7a2969a77ca539c1f9647d11ec 524 TIGRFAM TIGR02294 nickel_nikA: nickel ABC transporter, nickel/metallophore periplasmic binding protein 25 519 4.4E-218 T 29-03-2018 IPR011980 Nickel ABC transporter, substrate-binding protein NikA GO:0015675|GO:0016151|GO:0020037 MC49_RS02335 78e20f7a2969a77ca539c1f9647d11ec 524 Gene3D G3DSA:3.10.105.10 286 491 6.5E-50 T 29-03-2018 MC49_RS02335 78e20f7a2969a77ca539c1f9647d11ec 524 PIRSF PIRSF002741 27 520 1.6E-89 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MC49_RS02335 78e20f7a2969a77ca539c1f9647d11ec 524 SUPERFAMILY SSF53850 28 514 2.71E-124 T 29-03-2018 MC49_RS02335 78e20f7a2969a77ca539c1f9647d11ec 524 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 67 433 1.4E-86 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain MC49_RS02335 78e20f7a2969a77ca539c1f9647d11ec 524 Gene3D G3DSA:3.90.76.10 46 148 1.0E-26 T 29-03-2018 MC49_RS02335 78e20f7a2969a77ca539c1f9647d11ec 524 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 73 95 - T 29-03-2018 IPR023765 Solute-binding protein family 5, conserved site MC49_RS03660 761a846c96c82be910c900a4421fe5ad 64 Pfam PF12587 Protein of unknown function (DUF3761) 35 63 2.2E-8 T 29-03-2018 IPR022236 Protein of unknown function DUF3761 MC49_RS18785 17357a8bb029d2d43b929458a204c9de 182 Pfam PF00583 Acetyltransferase (GNAT) family 42 160 3.3E-4 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MC49_RS18785 17357a8bb029d2d43b929458a204c9de 182 Gene3D G3DSA:3.40.630.30 2 179 1.3E-11 T 29-03-2018 MC49_RS18785 17357a8bb029d2d43b929458a204c9de 182 SUPERFAMILY SSF55729 6 177 2.98E-12 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS09245 f949c80fb761a639e23f554a29344d0a 664 ProSitePatterns PS00801 Transketolase signature 1. 12 32 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MC49_RS09245 f949c80fb761a639e23f554a29344d0a 664 TIGRFAM TIGR00232 tktlase_bact: transketolase 6 663 0.0 T 29-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 MC49_RS09245 f949c80fb761a639e23f554a29344d0a 664 Gene3D G3DSA:3.40.50.970 1 364 6.0E-126 T 29-03-2018 MC49_RS09245 f949c80fb761a639e23f554a29344d0a 664 SUPERFAMILY SSF52518 5 321 1.47E-121 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MC49_RS09245 f949c80fb761a639e23f554a29344d0a 664 SMART SM00861 355 525 2.8E-68 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MC49_RS09245 f949c80fb761a639e23f554a29344d0a 664 SUPERFAMILY SSF52922 533 664 5.37E-44 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MC49_RS09245 f949c80fb761a639e23f554a29344d0a 664 SUPERFAMILY SSF52518 335 526 1.39E-69 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MC49_RS09245 f949c80fb761a639e23f554a29344d0a 664 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 4 334 1.7E-167 T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MC49_RS09245 f949c80fb761a639e23f554a29344d0a 664 ProSitePatterns PS00802 Transketolase signature 2. 467 483 - T 29-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MC49_RS09245 f949c80fb761a639e23f554a29344d0a 664 Gene3D G3DSA:3.40.50.920 541 664 7.7E-33 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 MC49_RS09245 f949c80fb761a639e23f554a29344d0a 664 Pfam PF02780 Transketolase, C-terminal domain 547 655 1.3E-18 T 29-03-2018 IPR033248 Transketolase, C-terminal domain MC49_RS09245 f949c80fb761a639e23f554a29344d0a 664 Gene3D G3DSA:3.40.50.970 365 540 3.0E-42 T 29-03-2018 MC49_RS09245 f949c80fb761a639e23f554a29344d0a 664 Pfam PF02779 Transketolase, pyrimidine binding domain 354 524 8.4E-47 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MC49_RS01575 15336e0f4400c11ed8c92802f3c14279 178 TIGRFAM TIGR03002 outer_YhbN_LptA: lipopolysaccharide transport periplasmic protein LptA 23 162 1.1E-44 T 29-03-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 MC49_RS01575 15336e0f4400c11ed8c92802f3c14279 178 Gene3D G3DSA:2.60.450.10 23 160 7.6E-26 T 29-03-2018 MC49_RS01575 15336e0f4400c11ed8c92802f3c14279 178 Hamap MF_01914 Lipopolysaccharide export system protein LptA [lptA]. 3 163 23.877 T 29-03-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 MC49_RS01575 15336e0f4400c11ed8c92802f3c14279 178 Pfam PF03968 OstA-like protein 34 144 5.9E-26 T 29-03-2018 IPR005653 Organic solvent tolerance-like, N-terminal MC49_RS12560 220b98387b0085afd33942201968c50a 546 SUPERFAMILY SSF64518 165 544 9.42E-41 T 29-03-2018 MC49_RS12560 220b98387b0085afd33942201968c50a 546 Gene3D G3DSA:3.90.20.10 6 205 0.0019 T 29-03-2018 MC49_RS12560 220b98387b0085afd33942201968c50a 546 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 491 542 3.2E-6 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain MC49_RS12560 220b98387b0085afd33942201968c50a 546 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 5 356 4.9E-68 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 MC49_RS12560 220b98387b0085afd33942201968c50a 546 PRINTS PR01005 Flagellar hook-associated protein signature 359 381 8.2E-51 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 MC49_RS12560 220b98387b0085afd33942201968c50a 546 PRINTS PR01005 Flagellar hook-associated protein signature 440 459 8.2E-51 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 MC49_RS12560 220b98387b0085afd33942201968c50a 546 PRINTS PR01005 Flagellar hook-associated protein signature 409 426 8.2E-51 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 MC49_RS12560 220b98387b0085afd33942201968c50a 546 PRINTS PR01005 Flagellar hook-associated protein signature 12 35 8.2E-51 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 MC49_RS12560 220b98387b0085afd33942201968c50a 546 PRINTS PR01005 Flagellar hook-associated protein signature 157 181 8.2E-51 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 MC49_RS12560 220b98387b0085afd33942201968c50a 546 PRINTS PR01005 Flagellar hook-associated protein signature 215 233 8.2E-51 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 MC49_RS12560 220b98387b0085afd33942201968c50a 546 PRINTS PR01005 Flagellar hook-associated protein signature 124 144 8.2E-51 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 MC49_RS12560 220b98387b0085afd33942201968c50a 546 PRINTS PR01005 Flagellar hook-associated protein signature 50 72 8.2E-51 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 MC49_RS12560 220b98387b0085afd33942201968c50a 546 PRINTS PR01005 Flagellar hook-associated protein signature 259 281 8.2E-51 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 MC49_RS12560 220b98387b0085afd33942201968c50a 546 PRINTS PR01005 Flagellar hook-associated protein signature 512 536 8.2E-51 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 MC49_RS12560 220b98387b0085afd33942201968c50a 546 PRINTS PR01005 Flagellar hook-associated protein signature 465 486 8.2E-51 T 29-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 MC49_RS13700 b3b2be4a87c7ecb546dbe9d9f952aa84 681 SUPERFAMILY SSF52096 354 545 1.51E-68 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MC49_RS13700 b3b2be4a87c7ecb546dbe9d9f952aa84 681 SUPERFAMILY SSF52096 177 268 1.51E-68 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MC49_RS13700 b3b2be4a87c7ecb546dbe9d9f952aa84 681 SMART SM00228 250 327 7.6E-8 T 29-03-2018 IPR001478 PDZ domain GO:0005515 MC49_RS13700 b3b2be4a87c7ecb546dbe9d9f952aa84 681 SUPERFAMILY SSF50156 223 346 1.09E-14 T 29-03-2018 IPR001478 PDZ domain GO:0005515 MC49_RS13700 b3b2be4a87c7ecb546dbe9d9f952aa84 681 Pfam PF03572 Peptidase family S41 360 533 2.7E-50 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 MC49_RS13700 b3b2be4a87c7ecb546dbe9d9f952aa84 681 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 244 324 1.5E-13 T 29-03-2018 IPR001478 PDZ domain GO:0005515 MC49_RS13700 b3b2be4a87c7ecb546dbe9d9f952aa84 681 Gene3D G3DSA:2.30.42.10 250 333 3.1E-13 T 29-03-2018 MC49_RS13700 b3b2be4a87c7ecb546dbe9d9f952aa84 681 Gene3D G3DSA:3.30.750.44 160 249 6.3E-23 T 29-03-2018 MC49_RS13700 b3b2be4a87c7ecb546dbe9d9f952aa84 681 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 198 555 2.0E-117 T 29-03-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 MC49_RS13700 b3b2be4a87c7ecb546dbe9d9f952aa84 681 SMART SM00245 330 535 2.0E-72 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 MC49_RS13700 b3b2be4a87c7ecb546dbe9d9f952aa84 681 Gene3D G3DSA:3.90.226.10 334 613 1.0E-55 T 29-03-2018 MC49_RS13700 b3b2be4a87c7ecb546dbe9d9f952aa84 681 Pfam PF11818 C-terminal domain of tail specific protease (DUF3340) 538 671 3.0E-36 T 29-03-2018 IPR020992 Tail specific protease, C-terminal MC49_RS16740 9b6a576f11747d1cec7ce78a23ac2d00 98 Gene3D G3DSA:3.30.70.860 19 98 8.7E-32 T 29-03-2018 IPR035571 UPF0234/UPF0381 domain MC49_RS16740 9b6a576f11747d1cec7ce78a23ac2d00 98 Pfam PF04175 Protein of unknown function (DUF406) 8 98 4.4E-38 T 29-03-2018 IPR005272 Conserved hypothetical protein CHP00743 MC49_RS16740 9b6a576f11747d1cec7ce78a23ac2d00 98 TIGRFAM TIGR00743 TIGR00743: conserved hypothetical protein 7 98 6.7E-39 T 29-03-2018 IPR005272 Conserved hypothetical protein CHP00743 MC49_RS02525 1504a6560306f39419b308ec6eabccaa 830 Pfam PF13954 PapC N-terminal domain 28 165 3.5E-33 T 29-03-2018 IPR025885 PapC, N-terminal domain GO:0005515 MC49_RS02525 1504a6560306f39419b308ec6eabccaa 830 Pfam PF13953 PapC C-terminal domain 758 818 1.1E-13 T 29-03-2018 IPR025949 PapC-like, C-terminal domain MC49_RS02525 1504a6560306f39419b308ec6eabccaa 830 SUPERFAMILY SSF141729 50 156 1.83E-20 T 29-03-2018 MC49_RS02525 1504a6560306f39419b308ec6eabccaa 830 Pfam PF00577 Outer membrane usher protein 181 747 5.7E-158 T 29-03-2018 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 MC49_RS11970 dbb99a936a64f4d234f600f5c357f652 299 SUPERFAMILY SSF103481 217 295 5.36E-10 T 29-03-2018 MC49_RS11970 dbb99a936a64f4d234f600f5c357f652 299 Pfam PF00892 EamA-like transporter family 151 292 4.3E-19 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MC49_RS11970 dbb99a936a64f4d234f600f5c357f652 299 Pfam PF00892 EamA-like transporter family 2 135 1.1E-21 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MC49_RS11970 dbb99a936a64f4d234f600f5c357f652 299 SUPERFAMILY SSF103481 37 138 4.71E-12 T 29-03-2018 MC49_RS13060 a368005acb85993e6e8a68fd831493b9 175 Pfam PF03592 Terminase small subunit 3 159 5.0E-39 T 29-03-2018 IPR005335 Terminase small subunit GO:0006323 MC49_RS16720 d941143b2d53277e02cdf35edd9fa3ba 181 SMART SM00463 95 173 1.0E-17 T 29-03-2018 IPR002625 Smr domain MC49_RS16720 d941143b2d53277e02cdf35edd9fa3ba 181 Pfam PF01713 Smr domain 98 169 5.5E-17 T 29-03-2018 IPR002625 Smr domain MC49_RS16720 d941143b2d53277e02cdf35edd9fa3ba 181 SUPERFAMILY SSF160443 96 150 3.01E-9 T 29-03-2018 IPR002625 Smr domain MC49_RS16720 d941143b2d53277e02cdf35edd9fa3ba 181 Hamap MF_01042 UPF0115 protein YfcN [yfcN]. 1 174 38.737 T 29-03-2018 IPR022990 Uncharacterised protein family UPF0115 MC49_RS01225 d0f73f8010af24b652c292bdea3df668 688 Gene3D G3DSA:1.10.287.1060 320 401 0.0032 T 29-03-2018 MC49_RS01225 d0f73f8010af24b652c292bdea3df668 688 SUPERFAMILY SSF109709 121 219 7.19E-19 T 29-03-2018 MC49_RS01225 d0f73f8010af24b652c292bdea3df668 688 SUPERFAMILY SSF110849 29 148 6.28E-14 T 29-03-2018 IPR003115 ParB/Sulfiredoxin MC49_RS01225 d0f73f8010af24b652c292bdea3df668 688 SMART SM00470 30 127 1.2E-15 T 29-03-2018 IPR003115 ParB/Sulfiredoxin MC49_RS01225 d0f73f8010af24b652c292bdea3df668 688 Gene3D G3DSA:3.90.1530.10 18 127 4.5E-20 T 29-03-2018 MC49_RS01225 d0f73f8010af24b652c292bdea3df668 688 Pfam PF02195 ParB-like nuclease domain 32 126 1.7E-11 T 29-03-2018 IPR003115 ParB/Sulfiredoxin MC49_RS01225 d0f73f8010af24b652c292bdea3df668 688 Gene3D G3DSA:1.10.10.730 128 173 1.1E-9 T 29-03-2018 MC49_RS18420 103dac65c7a6dc0e0d2a403507901f70 95 Gene3D G3DSA:1.10.150.250 2 86 1.3E-26 T 29-03-2018 MC49_RS18420 103dac65c7a6dc0e0d2a403507901f70 95 SUPERFAMILY SSF109910 2 79 2.35E-27 T 29-03-2018 IPR005631 Flavinator of succinate dehydrogenase MC49_RS18420 103dac65c7a6dc0e0d2a403507901f70 95 Pfam PF03937 Flavinator of succinate dehydrogenase 7 77 2.6E-26 T 29-03-2018 IPR005631 Flavinator of succinate dehydrogenase MC49_RS12750 fb382572ea87ab82223ba4912f56e99f 137 Gene3D G3DSA:3.30.70.790 13 81 2.9E-13 T 29-03-2018 MC49_RS12750 fb382572ea87ab82223ba4912f56e99f 137 SUPERFAMILY SSF54913 19 78 6.45E-6 T 29-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta MC49_RS12750 fb382572ea87ab82223ba4912f56e99f 137 Pfam PF09413 Putative prokaryotic signal transducing protein 19 77 1.7E-6 T 29-03-2018 IPR018551 Domain of unknown function DUF2007 MC49_RS13120 0a2ab33daee7505a8f72b94b874bcdab 1107 Gene3D G3DSA:3.40.190.10 68 501 0.35 T 29-03-2018 MC49_RS13120 0a2ab33daee7505a8f72b94b874bcdab 1107 Pfam PF06120 Tail length tape measure protein 399 662 3.8E-15 T 29-03-2018 IPR009302 Tail length tape measure MC49_RS13120 0a2ab33daee7505a8f72b94b874bcdab 1107 TIGRFAM TIGR02675 tape_meas_nterm: tape measure domain 142 215 9.3E-24 T 29-03-2018 IPR013491 Caudovirus, tape measure, N-terminal MC49_RS02900 7f071dbf09f6d16457bd1ba306a44128 97 SUPERFAMILY SSF47413 9 71 8.04E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS02900 7f071dbf09f6d16457bd1ba306a44128 97 Pfam PF01381 Helix-turn-helix 16 69 3.1E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS02900 7f071dbf09f6d16457bd1ba306a44128 97 Gene3D G3DSA:1.10.260.40 2 78 1.4E-18 T 29-03-2018 MC49_RS02900 7f071dbf09f6d16457bd1ba306a44128 97 SMART SM00530 15 70 1.5E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS14845 ea213383b531cced6798c849af67bd8e 235 SUPERFAMILY SSF55729 27 198 2.88E-38 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS14845 ea213383b531cced6798c849af67bd8e 235 Gene3D G3DSA:3.40.630.30 16 206 1.7E-29 T 29-03-2018 MC49_RS14845 ea213383b531cced6798c849af67bd8e 235 Pfam PF13302 Acetyltransferase (GNAT) domain 36 174 2.3E-15 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MC49_RS04430 62f78a2988376e8b05097a5da0195545 495 Gene3D G3DSA:3.30.9.10 85 180 8.5E-18 T 29-03-2018 MC49_RS04430 62f78a2988376e8b05097a5da0195545 495 Gene3D G3DSA:3.30.9.10 181 320 4.2E-38 T 29-03-2018 MC49_RS04430 62f78a2988376e8b05097a5da0195545 495 Pfam PF01266 FAD dependent oxidoreductase 5 323 1.3E-49 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MC49_RS04430 62f78a2988376e8b05097a5da0195545 495 SUPERFAMILY SSF54373 226 319 1.84E-7 T 29-03-2018 MC49_RS04430 62f78a2988376e8b05097a5da0195545 495 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 9 26 - T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 MC49_RS04430 62f78a2988376e8b05097a5da0195545 495 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 4 16 6.4E-28 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 MC49_RS04430 62f78a2988376e8b05097a5da0195545 495 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 33 45 6.4E-28 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 MC49_RS04430 62f78a2988376e8b05097a5da0195545 495 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 17 27 6.4E-28 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 MC49_RS04430 62f78a2988376e8b05097a5da0195545 495 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 78 90 6.4E-28 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 MC49_RS04430 62f78a2988376e8b05097a5da0195545 495 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 313 319 6.4E-28 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 MC49_RS04430 62f78a2988376e8b05097a5da0195545 495 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 347 359 6.4E-28 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 MC49_RS04430 62f78a2988376e8b05097a5da0195545 495 SUPERFAMILY SSF51905 312 374 6.91E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS04430 62f78a2988376e8b05097a5da0195545 495 SUPERFAMILY SSF51905 1 260 6.91E-35 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS04430 62f78a2988376e8b05097a5da0195545 495 Gene3D G3DSA:3.40.50.720 3 84 0.0018 T 29-03-2018 MC49_RS04430 62f78a2988376e8b05097a5da0195545 495 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 381 480 2.6E-12 T 29-03-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 MC49_RS14945 086e80534ecbfee21d738e8a5227d20b 121 ProDom PD073251 YNFB PERIPLASMIC SECRETED ORF9 PRECURSOR SIGNAL SIMILAR ECS2289 EXPORTED ESCHERICHIA 32 116 4.0E-27 T 29-03-2018 IPR009700 Protein of unknown function DUF1283 MC49_RS14945 086e80534ecbfee21d738e8a5227d20b 121 Pfam PF06932 Protein of unknown function (DUF1283) 36 117 3.8E-40 T 29-03-2018 IPR009700 Protein of unknown function DUF1283 MC49_RS09630 07ea99c5b02c391e25f9fbe50473c6e5 187 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 1 187 38.743 T 29-03-2018 IPR003774 Protein of unknown function UPF0301 MC49_RS09630 07ea99c5b02c391e25f9fbe50473c6e5 187 Pfam PF02622 Uncharacterized ACR, COG1678 12 174 3.0E-50 T 29-03-2018 IPR003774 Protein of unknown function UPF0301 MC49_RS09630 07ea99c5b02c391e25f9fbe50473c6e5 187 SUPERFAMILY SSF143456 1 187 3.14E-64 T 29-03-2018 MC49_RS09630 07ea99c5b02c391e25f9fbe50473c6e5 187 Gene3D G3DSA:3.40.1740.10 1 94 2.3E-28 T 29-03-2018 MC49_RS09630 07ea99c5b02c391e25f9fbe50473c6e5 187 Gene3D G3DSA:3.40.1740.10 95 179 2.0E-10 T 29-03-2018 MC49_RS05405 8173b556ead3ba934b9337c2ed30c61f 254 Gene3D G3DSA:3.40.630.30 5 219 4.1E-19 T 29-03-2018 MC49_RS05405 8173b556ead3ba934b9337c2ed30c61f 254 Pfam PF00583 Acetyltransferase (GNAT) family 57 155 8.3E-5 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MC49_RS05405 8173b556ead3ba934b9337c2ed30c61f 254 SUPERFAMILY SSF55729 18 152 1.98E-9 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS08620 4c3b22567f8a13159fda67f91ac83561 186 SMART SM00877 3 79 8.7E-30 T 29-03-2018 IPR000249 Microcompartment protein, bacteria MC49_RS08620 4c3b22567f8a13159fda67f91ac83561 186 Pfam PF16365 Ethanolamine utilization protein EutK C-terminus 133 177 2.8E-14 T 29-03-2018 IPR032298 Ethanolamine utilization protein EutK, C-terminal MC49_RS08620 4c3b22567f8a13159fda67f91ac83561 186 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 4 54 1.0E-13 T 29-03-2018 MC49_RS08620 4c3b22567f8a13159fda67f91ac83561 186 SUPERFAMILY SSF143414 3 88 1.03E-25 T 29-03-2018 MC49_RS08620 4c3b22567f8a13159fda67f91ac83561 186 Pfam PF00936 BMC domain 4 79 2.3E-24 T 29-03-2018 IPR000249 Microcompartment protein, bacteria MC49_RS06440 1fce4a46794fbb5f02f62bb5b840c3bd 267 Gene3D G3DSA:1.10.1660.10 1 62 1.1E-21 T 29-03-2018 MC49_RS06440 1fce4a46794fbb5f02f62bb5b840c3bd 267 SUPERFAMILY SSF46955 3 111 3.3E-26 T 29-03-2018 IPR009061 Putative DNA-binding domain MC49_RS06440 1fce4a46794fbb5f02f62bb5b840c3bd 267 SMART SM00422 5 75 5.5E-16 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MC49_RS06440 1fce4a46794fbb5f02f62bb5b840c3bd 267 Pfam PF13411 MerR HTH family regulatory protein 5 74 3.9E-19 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MC49_RS06440 1fce4a46794fbb5f02f62bb5b840c3bd 267 Gene3D G3DSA:1.10.1660.10 63 126 2.4E-4 T 29-03-2018 MC49_RS17320 b0e6a48293887e94142d6fe9e5683b8d 209 SUPERFAMILY SSF110849 45 179 3.49E-21 T 29-03-2018 IPR003115 ParB/Sulfiredoxin MC49_RS17320 b0e6a48293887e94142d6fe9e5683b8d 209 Pfam PF02195 ParB-like nuclease domain 48 145 2.6E-8 T 29-03-2018 IPR003115 ParB/Sulfiredoxin MC49_RS17320 b0e6a48293887e94142d6fe9e5683b8d 209 SMART SM00470 47 146 2.0E-4 T 29-03-2018 IPR003115 ParB/Sulfiredoxin MC49_RS17320 b0e6a48293887e94142d6fe9e5683b8d 209 Gene3D G3DSA:3.90.1530.10 34 150 2.0E-9 T 29-03-2018 MC49_RS11660 b317e17f65646c3176a9740629eedada 195 Gene3D G3DSA:3.40.50.1240 16 187 1.5E-12 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MC49_RS11660 b317e17f65646c3176a9740629eedada 195 SUPERFAMILY SSF53254 23 118 1.96E-7 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MC49_RS13310 1c883c4418540f26656e77af63f47dc9 707 SUPERFAMILY SSF52540 458 705 1.2E-88 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS13310 1c883c4418540f26656e77af63f47dc9 707 Pfam PF03412 Peptidase C39 family 5 129 4.4E-28 T 29-03-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 MC49_RS13310 1c883c4418540f26656e77af63f47dc9 707 Pfam PF00664 ABC transporter transmembrane region 157 424 2.8E-59 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MC49_RS13310 1c883c4418540f26656e77af63f47dc9 707 Gene3D G3DSA:1.20.1560.10 134 454 1.1E-43 T 29-03-2018 MC49_RS13310 1c883c4418540f26656e77af63f47dc9 707 SMART SM00382 494 680 7.7E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS13310 1c883c4418540f26656e77af63f47dc9 707 TIGRFAM TIGR01846 type_I_sec_HlyB: type I secretion system ATPase 10 707 0.0 T 29-03-2018 IPR010132 ATPase, type I secretion system, HlyB GO:0005524|GO:0008565|GO:0016021|GO:0030253|GO:0030256 MC49_RS13310 1c883c4418540f26656e77af63f47dc9 707 Gene3D G3DSA:3.40.50.300 455 707 1.3E-75 T 29-03-2018 MC49_RS13310 1c883c4418540f26656e77af63f47dc9 707 Gene3D G3DSA:3.90.70.10 2 133 8.2E-20 T 29-03-2018 MC49_RS13310 1c883c4418540f26656e77af63f47dc9 707 ProSitePatterns PS00211 ABC transporters family signature. 606 620 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS13310 1c883c4418540f26656e77af63f47dc9 707 Pfam PF00005 ABC transporter 485 634 3.6E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS13310 1c883c4418540f26656e77af63f47dc9 707 SUPERFAMILY SSF90123 142 453 3.4E-66 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 MC49_RS14700 7ca5e993e20ac145b721aeaaa8c88bf5 405 Gene3D G3DSA:1.20.190.10 21 232 6.0E-16 T 29-03-2018 MC49_RS14700 7ca5e993e20ac145b721aeaaa8c88bf5 405 Gene3D G3DSA:2.60.120.260 233 405 6.6E-4 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS14700 7ca5e993e20ac145b721aeaaa8c88bf5 405 SUPERFAMILY SSF56849 46 197 1.83E-7 T 29-03-2018 IPR005639 Pesticidal crystal protein, N-terminal GO:0009405|GO:0090729 MC49_RS07685 de47457c7f23a1f1704ffedcd0fc44c8 324 SUPERFAMILY SSF55154 5 224 6.21E-49 T 29-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 MC49_RS07685 de47457c7f23a1f1704ffedcd0fc44c8 324 Pfam PF01928 CYTH domain 6 199 6.3E-28 T 29-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 MC49_RS07685 de47457c7f23a1f1704ffedcd0fc44c8 324 SMART SM01118 5 205 8.9E-35 T 29-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 MC49_RS07685 de47457c7f23a1f1704ffedcd0fc44c8 324 Gene3D G3DSA:2.40.320.10 3 210 6.2E-44 T 29-03-2018 MC49_RS08250 ade4790e515aedcad611c42eaeea60de 208 Gene3D G3DSA:3.40.50.150 1 206 3.0E-40 T 29-03-2018 MC49_RS08250 ade4790e515aedcad611c42eaeea60de 208 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 7 204 8.9E-68 T 29-03-2018 MC49_RS08250 ade4790e515aedcad611c42eaeea60de 208 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 130 145 - T 29-03-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 MC49_RS08250 ade4790e515aedcad611c42eaeea60de 208 SUPERFAMILY SSF53335 12 205 3.19E-48 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS08250 ade4790e515aedcad611c42eaeea60de 208 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 1 208 37.766 T 29-03-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 MC49_RS08250 ade4790e515aedcad611c42eaeea60de 208 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 3 205 1.8E-78 T 29-03-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 MC49_RS14110 8618ffda286cea64efbf04d9d4d8cf9d 491 SUPERFAMILY SSF51735 5 189 2.95E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS14110 8618ffda286cea64efbf04d9d4d8cf9d 491 Gene3D G3DSA:3.40.50.720 7 187 2.9E-61 T 29-03-2018 MC49_RS14110 8618ffda286cea64efbf04d9d4d8cf9d 491 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 176 182 - T 29-03-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MC49_RS14110 8618ffda286cea64efbf04d9d4d8cf9d 491 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 188 488 1.2E-113 T 29-03-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MC49_RS14110 8618ffda286cea64efbf04d9d4d8cf9d 491 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 9 489 88.6 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MC49_RS14110 8618ffda286cea64efbf04d9d4d8cf9d 491 PIRSF PIRSF000110 1 491 4.2E-178 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MC49_RS14110 8618ffda286cea64efbf04d9d4d8cf9d 491 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 9 489 3.6E-193 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MC49_RS14110 8618ffda286cea64efbf04d9d4d8cf9d 491 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 13 186 4.3E-58 T 29-03-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MC49_RS14110 8618ffda286cea64efbf04d9d4d8cf9d 491 Gene3D G3DSA:3.30.360.10 188 490 9.2E-124 T 29-03-2018 MC49_RS14110 8618ffda286cea64efbf04d9d4d8cf9d 491 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 218 235 7.6E-47 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MC49_RS14110 8618ffda286cea64efbf04d9d4d8cf9d 491 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 236 252 7.6E-47 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MC49_RS14110 8618ffda286cea64efbf04d9d4d8cf9d 491 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 142 155 7.6E-47 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MC49_RS14110 8618ffda286cea64efbf04d9d4d8cf9d 491 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 166 194 7.6E-47 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MC49_RS14110 8618ffda286cea64efbf04d9d4d8cf9d 491 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 327 353 7.6E-47 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MC49_RS14110 8618ffda286cea64efbf04d9d4d8cf9d 491 SUPERFAMILY SSF55347 176 488 8.83E-112 T 29-03-2018 MC49_RS10205 2c90347235963576bbd9b47a110c93f6 296 SMART SM00116 141 189 0.91 T 29-03-2018 IPR000644 CBS domain MC49_RS10205 2c90347235963576bbd9b47a110c93f6 296 SMART SM00116 78 127 12.0 T 29-03-2018 IPR000644 CBS domain MC49_RS10205 2c90347235963576bbd9b47a110c93f6 296 Pfam PF00571 CBS domain 69 124 1.3E-7 T 29-03-2018 IPR000644 CBS domain MC49_RS10205 2c90347235963576bbd9b47a110c93f6 296 Pfam PF00571 CBS domain 141 189 1.9E-5 T 29-03-2018 IPR000644 CBS domain MC49_RS10205 2c90347235963576bbd9b47a110c93f6 296 Gene3D G3DSA:3.30.465.10 200 281 6.7E-26 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 MC49_RS10205 2c90347235963576bbd9b47a110c93f6 296 SMART SM01091 205 283 3.6E-28 T 29-03-2018 IPR005170 Transporter-associated domain MC49_RS10205 2c90347235963576bbd9b47a110c93f6 296 Gene3D G3DSA:3.10.580.10 50 199 2.5E-34 T 29-03-2018 MC49_RS10205 2c90347235963576bbd9b47a110c93f6 296 Pfam PF03471 Transporter associated domain 207 281 3.3E-21 T 29-03-2018 IPR005170 Transporter-associated domain MC49_RS10205 2c90347235963576bbd9b47a110c93f6 296 SUPERFAMILY SSF56176 204 286 9.82E-22 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 MC49_RS10205 2c90347235963576bbd9b47a110c93f6 296 SUPERFAMILY SSF54631 65 202 4.67E-32 T 29-03-2018 MC49_RS13775 aebac0741cb548eaf11e392ee1ddf513 158 Hamap MF_01191 UPF0442 protein YjjB [yjjB]. 2 158 35.687 T 29-03-2018 IPR020914 Uncharacterised protein family UPF0442 MC49_RS13775 aebac0741cb548eaf11e392ee1ddf513 158 Pfam PF12821 Threonine/Serine exporter, ThrE 14 148 2.9E-34 T 29-03-2018 IPR024528 Threonine/Serine exporter, ThrE MC49_RS01505 9883d315c60690f1001de4158f6d8935 277 SUPERFAMILY SSF51197 3 277 3.02E-89 T 29-03-2018 MC49_RS01505 9883d315c60690f1001de4158f6d8935 277 Gene3D G3DSA:3.60.130.10 1 277 8.9E-70 T 29-03-2018 MC49_RS01505 9883d315c60690f1001de4158f6d8935 277 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 5 270 4.9E-59 T 29-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 MC49_RS10025 e44525f0f496121b85807d36fb877dd2 332 SUPERFAMILY SSF53850 24 328 3.08E-96 T 29-03-2018 MC49_RS10025 e44525f0f496121b85807d36fb877dd2 332 Gene3D G3DSA:3.40.190.10 21 159 1.8E-16 T 29-03-2018 MC49_RS10025 e44525f0f496121b85807d36fb877dd2 332 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 36 313 8.5E-59 T 29-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 MC49_RS10025 e44525f0f496121b85807d36fb877dd2 332 Gene3D G3DSA:3.40.190.10 160 326 1.8E-35 T 29-03-2018 MC49_RS15215 f6e0fb299d1288a3681aea93567a7ac1 576 SUPERFAMILY SSF52091 430 522 4.12E-6 T 29-03-2018 IPR002645 STAS domain MC49_RS15215 f6e0fb299d1288a3681aea93567a7ac1 576 Pfam PF01740 STAS domain 434 519 2.4E-8 T 29-03-2018 IPR002645 STAS domain MC49_RS15215 f6e0fb299d1288a3681aea93567a7ac1 576 Pfam PF00916 Sulfate permease family 16 380 4.2E-83 T 29-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 MC49_RS15215 f6e0fb299d1288a3681aea93567a7ac1 576 Gene3D G3DSA:3.30.750.24 430 557 2.6E-13 T 29-03-2018 IPR002645 STAS domain MC49_RS08500 72c5b7a00696f2585697b47f4104636c 457 Pfam PF07287 Acyclic terpene utilisation family protein AtuA 60 334 7.0E-21 T 29-03-2018 IPR010839 Acyclic terpene utilisation MC49_RS02945 d9dcedb935674e88e368721b19e16112 303 SUPERFAMILY SSF46785 10 118 1.4E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS02945 d9dcedb935674e88e368721b19e16112 303 Gene3D G3DSA:3.40.190.10 184 269 3.1E-24 T 29-03-2018 MC49_RS02945 d9dcedb935674e88e368721b19e16112 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 68 7.8E-19 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS02945 d9dcedb935674e88e368721b19e16112 303 Gene3D G3DSA:3.40.190.10 98 183 3.3E-15 T 29-03-2018 MC49_RS02945 d9dcedb935674e88e368721b19e16112 303 Gene3D G3DSA:1.10.10.10 5 90 3.1E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS02945 d9dcedb935674e88e368721b19e16112 303 SUPERFAMILY SSF53850 96 302 4.89E-40 T 29-03-2018 MC49_RS02945 d9dcedb935674e88e368721b19e16112 303 Pfam PF03466 LysR substrate binding domain 94 301 1.2E-37 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS15605 bc114098d17e968d0bca7dfd6db6757a 328 Gene3D G3DSA:1.10.8.60 181 240 4.8E-18 T 29-03-2018 MC49_RS15605 bc114098d17e968d0bca7dfd6db6757a 328 SUPERFAMILY SSF52540 8 242 1.56E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS15605 bc114098d17e968d0bca7dfd6db6757a 328 Gene3D G3DSA:3.40.50.300 1 179 2.0E-28 T 29-03-2018 MC49_RS15605 bc114098d17e968d0bca7dfd6db6757a 328 SMART SM00382 28 180 4.9E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS15605 bc114098d17e968d0bca7dfd6db6757a 328 Pfam PF02954 Bacterial regulatory protein, Fis family 285 316 8.0E-6 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MC49_RS15605 bc114098d17e968d0bca7dfd6db6757a 328 SUPERFAMILY SSF46689 222 321 8.06E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS15605 bc114098d17e968d0bca7dfd6db6757a 328 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 94 109 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MC49_RS15605 bc114098d17e968d0bca7dfd6db6757a 328 TIGRFAM TIGR02974 phageshock_pspF: psp operon transcriptional activator 8 321 2.7E-151 T 29-03-2018 IPR014317 Transcription activator PspF MC49_RS15605 bc114098d17e968d0bca7dfd6db6757a 328 Gene3D G3DSA:1.10.10.60 241 322 3.4E-6 T 29-03-2018 MC49_RS15605 bc114098d17e968d0bca7dfd6db6757a 328 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 222 231 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site MC49_RS15605 bc114098d17e968d0bca7dfd6db6757a 328 Pfam PF00158 Sigma-54 interaction domain 9 170 5.7E-62 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MC49_RS08280 9ef15344e635eb4b74b210e15e57bbec 380 Gene3D G3DSA:2.40.160.50 39 380 5.3E-37 T 29-03-2018 MC49_RS08280 9ef15344e635eb4b74b210e15e57bbec 380 Pfam PF01103 Surface antigen 112 380 2.8E-11 T 29-03-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 MC49_RS00280 60f949287d2ca39ccb2b458a8a9e717a 137 Gene3D G3DSA:1.10.10.10 11 115 4.6E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS18240 a3a26778790d70db8a1a56114f6fe610 174 Pfam PF03974 Ecotin 42 163 5.4E-48 T 29-03-2018 IPR023189 Proteinase inhibitor I11, ecotin domain MC49_RS18240 a3a26778790d70db8a1a56114f6fe610 174 SUPERFAMILY SSF49772 42 170 7.32E-50 T 29-03-2018 IPR023189 Proteinase inhibitor I11, ecotin domain MC49_RS18240 a3a26778790d70db8a1a56114f6fe610 174 Gene3D G3DSA:4.10.1230.10 117 171 7.6E-25 T 29-03-2018 IPR027438 Ecotin, C-terminal MC49_RS18240 a3a26778790d70db8a1a56114f6fe610 174 PIRSF PIRSF006865 8 174 2.3E-51 T 29-03-2018 IPR005658 Proteinase inhibitor I11, ecotin MC49_RS18240 a3a26778790d70db8a1a56114f6fe610 174 Gene3D G3DSA:2.60.40.550 39 110 2.3E-26 T 29-03-2018 MC49_RS06915 9238ac8af5d3aa206f6b1e80608c21c0 232 TIGRFAM TIGR01600 phage_tail_L: phage minor tail protein L 15 229 2.7E-72 T 29-03-2018 IPR006487 Bacteriophage lambda, GpL, minor tail MC49_RS06915 9238ac8af5d3aa206f6b1e80608c21c0 232 Pfam PF05100 Phage minor tail protein L 29 230 4.6E-71 T 29-03-2018 IPR006487 Bacteriophage lambda, GpL, minor tail MC49_RS11485 a6cf3e0716e8d429ccc3452fd9875434 78 Gene3D G3DSA:1.10.3100.10 1 77 1.1E-18 T 29-03-2018 IPR027910 YdiL-like domain MC49_RS11485 a6cf3e0716e8d429ccc3452fd9875434 78 SMART SM00530 11 66 1.8E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS11485 a6cf3e0716e8d429ccc3452fd9875434 78 Pfam PF01381 Helix-turn-helix 12 65 4.1E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS11485 a6cf3e0716e8d429ccc3452fd9875434 78 SUPERFAMILY SSF47413 1 73 2.28E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS18915 27358197dcc72efda9265bb259da35f4 466 PRINTS PR00762 Chloride channel signature 99 116 1.7E-27 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MC49_RS18915 27358197dcc72efda9265bb259da35f4 466 PRINTS PR00762 Chloride channel signature 402 421 1.7E-27 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MC49_RS18915 27358197dcc72efda9265bb259da35f4 466 PRINTS PR00762 Chloride channel signature 180 199 1.7E-27 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MC49_RS18915 27358197dcc72efda9265bb259da35f4 466 PRINTS PR00762 Chloride channel signature 349 369 1.7E-27 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MC49_RS18915 27358197dcc72efda9265bb259da35f4 466 PRINTS PR00762 Chloride channel signature 384 400 1.7E-27 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MC49_RS18915 27358197dcc72efda9265bb259da35f4 466 Gene3D G3DSA:1.10.3080.10 13 455 2.2E-100 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 MC49_RS18915 27358197dcc72efda9265bb259da35f4 466 Pfam PF00654 Voltage gated chloride channel 87 434 7.4E-91 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MC49_RS18915 27358197dcc72efda9265bb259da35f4 466 SUPERFAMILY SSF81340 18 450 3.79E-104 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 MC49_RS16050 0dd5aba66bc3134917b4cb5b36b6578d 129 SUPERFAMILY SSF54593 4 127 1.3E-27 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MC49_RS16050 0dd5aba66bc3134917b4cb5b36b6578d 129 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 126 1.9E-17 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MC49_RS16050 0dd5aba66bc3134917b4cb5b36b6578d 129 Gene3D G3DSA:3.10.180.10 1 129 4.7E-25 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MC49_RS00230 8015010c0ea932e402e5a6d31ebf389c 175 Pfam PF03592 Terminase small subunit 3 159 1.8E-39 T 29-03-2018 IPR005335 Terminase small subunit GO:0006323 MC49_RS06760 a9d19151a8c4beab8c036ec928f4b167 64 Pfam PF13973 Domain of unknown function (DUF4222) 8 58 3.3E-19 T 29-03-2018 IPR025317 Protein of unknown function DUF4222 MC49_RS17045 b553790c808f7c240c7e74b223adceaa 280 Hamap MF_01604 Thiamine kinase [thiK]. 1 277 38.554 T 29-03-2018 IPR014093 Thiamine kinase GO:0006772|GO:0016310|GO:0019165 KEGG: 00730+2.7.1.89|MetaCyc: PWY-6896 MC49_RS17045 b553790c808f7c240c7e74b223adceaa 280 SUPERFAMILY SSF56112 56 260 1.17E-26 T 29-03-2018 IPR011009 Protein kinase-like domain MC49_RS17045 b553790c808f7c240c7e74b223adceaa 280 Pfam PF01633 Choline/ethanolamine kinase 59 212 1.3E-10 T 29-03-2018 MC49_RS17045 b553790c808f7c240c7e74b223adceaa 280 Gene3D G3DSA:3.90.1200.10 54 269 3.4E-23 T 29-03-2018 MC49_RS16965 65784eeae203d54d2848f32becd94180 373 Pfam PF08007 Cupin superfamily protein 9 310 1.1E-95 T 29-03-2018 IPR003347 JmjC domain MC49_RS16965 65784eeae203d54d2848f32becd94180 373 Gene3D G3DSA:2.60.120.650 3 208 3.0E-26 T 29-03-2018 MC49_RS16965 65784eeae203d54d2848f32becd94180 373 SMART SM00558 87 215 7.8E-6 T 29-03-2018 IPR003347 JmjC domain MC49_RS16965 65784eeae203d54d2848f32becd94180 373 SUPERFAMILY SSF51197 6 291 1.13E-70 T 29-03-2018 MC49_RS04740 4dd228ad7c7a5dc165d1a9625a87060c 707 Pfam PF07095 Intracellular growth attenuator protein IgaA 1 701 9.8E-301 T 29-03-2018 IPR010771 Intracellular growth attenuator IgaA GO:0009276|GO:0016021 MC49_RS04740 4dd228ad7c7a5dc165d1a9625a87060c 707 ProDom PD147088 MEMBRANE INNER TRANSMEMBRANE IGAA HOMOLOG DEHYDROGENASE GROWTH ATTENUATOR INTRACELLULAR GENOME 12 696 5.0E-156 T 29-03-2018 IPR010771 Intracellular growth attenuator IgaA GO:0009276|GO:0016021 MC49_RS04740 4dd228ad7c7a5dc165d1a9625a87060c 707 Gene3D G3DSA:1.20.5.900 647 694 4.1E-5 T 29-03-2018 MC49_RS03700 822861fe01a465802c6d49e6a673eb26 723 TIGRFAM TIGR01075 uvrD: DNA helicase II 9 721 0.0 T 29-03-2018 IPR005753 DNA helicase, ATP-dependent, UvrD type GO:0004003|GO:0005737|GO:0006268 MC49_RS03700 822861fe01a465802c6d49e6a673eb26 723 Pfam PF00580 UvrD/REP helicase N-terminal domain 13 274 8.1E-73 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 MC49_RS03700 822861fe01a465802c6d49e6a673eb26 723 Pfam PF13361 UvrD-like helicase C-terminal domain 280 619 7.9E-73 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MC49_RS03700 822861fe01a465802c6d49e6a673eb26 723 SUPERFAMILY SSF52540 10 645 1.61E-178 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS03700 822861fe01a465802c6d49e6a673eb26 723 Gene3D G3DSA:3.40.50.300 286 386 4.2E-27 T 29-03-2018 MC49_RS03700 822861fe01a465802c6d49e6a673eb26 723 Gene3D G3DSA:3.40.50.300 7 149 2.9E-28 T 29-03-2018 MC49_RS03700 822861fe01a465802c6d49e6a673eb26 723 Gene3D G3DSA:3.40.50.300 152 285 3.1E-32 T 29-03-2018 MC49_RS03700 822861fe01a465802c6d49e6a673eb26 723 Gene3D G3DSA:1.10.486.10 387 553 5.9E-44 T 29-03-2018 MC49_RS08570 6f200cbca130ec44016a73094d11e94f 97 SUPERFAMILY SSF143414 1 90 3.53E-31 T 29-03-2018 MC49_RS08570 6f200cbca130ec44016a73094d11e94f 97 SMART SM00877 2 78 5.4E-35 T 29-03-2018 IPR000249 Microcompartment protein, bacteria MC49_RS08570 6f200cbca130ec44016a73094d11e94f 97 Pfam PF00936 BMC domain 3 78 4.9E-27 T 29-03-2018 IPR000249 Microcompartment protein, bacteria MC49_RS08570 6f200cbca130ec44016a73094d11e94f 97 ProSitePatterns PS01139 Bacterial microcompartiments proteins signature. 20 39 - T 29-03-2018 IPR020808 Bacterial microcompartments protein, conserved site MC49_RS08570 6f200cbca130ec44016a73094d11e94f 97 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 2 48 4.0E-17 T 29-03-2018 MC49_RS11940 ec99436f5b788110edb4bcc9afb7b16f 341 Pfam PF06996 Type VI secretion, TssG 24 327 5.4E-89 T 29-03-2018 IPR010732 Type VI secretion, TssG-like MC49_RS11940 ec99436f5b788110edb4bcc9afb7b16f 341 TIGRFAM TIGR03347 VI_chp_1: type VI secretion protein, VC_A0111 family 24 327 1.4E-90 T 29-03-2018 IPR010732 Type VI secretion, TssG-like MC49_RS12150 4a7e7a876a9267d8cb6270ab6a820b5b 140 Pfam PF14581 SseB protein C-terminal domain 12 125 7.0E-29 T 29-03-2018 IPR027945 SseB protein, C-terminal MC49_RS12820 8c030e67e20756f99228365e9d2a8f66 764 SUPERFAMILY SSF51998 222 740 8.24E-171 T 29-03-2018 MC49_RS12820 8c030e67e20756f99228365e9d2a8f66 764 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 599 621 - T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MC49_RS12820 8c030e67e20756f99228365e9d2a8f66 764 Pfam PF02867 Ribonucleotide reductase, barrel domain 223 731 2.8E-119 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MC49_RS12820 8c030e67e20756f99228365e9d2a8f66 764 SUPERFAMILY SSF48168 10 221 4.05E-72 T 29-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MC49_RS12820 8c030e67e20756f99228365e9d2a8f66 764 Pfam PF03477 ATP cone domain 6 92 1.6E-15 T 29-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 MC49_RS12820 8c030e67e20756f99228365e9d2a8f66 764 PRINTS PR01183 Ribonucleotide reductase large chain signature 511 533 8.0E-40 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MC49_RS12820 8c030e67e20756f99228365e9d2a8f66 764 PRINTS PR01183 Ribonucleotide reductase large chain signature 610 637 8.0E-40 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MC49_RS12820 8c030e67e20756f99228365e9d2a8f66 764 PRINTS PR01183 Ribonucleotide reductase large chain signature 433 444 8.0E-40 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MC49_RS12820 8c030e67e20756f99228365e9d2a8f66 764 PRINTS PR01183 Ribonucleotide reductase large chain signature 473 496 8.0E-40 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MC49_RS12820 8c030e67e20756f99228365e9d2a8f66 764 PRINTS PR01183 Ribonucleotide reductase large chain signature 298 317 8.0E-40 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MC49_RS12820 8c030e67e20756f99228365e9d2a8f66 764 PRINTS PR01183 Ribonucleotide reductase large chain signature 539 562 8.0E-40 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MC49_RS12820 8c030e67e20756f99228365e9d2a8f66 764 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 145 735 7.9E-180 T 29-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MC49_RS12820 8c030e67e20756f99228365e9d2a8f66 764 Gene3D G3DSA:3.20.70.20 122 739 1.5E-149 T 29-03-2018 MC49_RS12820 8c030e67e20756f99228365e9d2a8f66 764 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 141 219 3.3E-12 T 29-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MC49_RS11290 a58a8d422e2e47ede048a8d3f13e34a1 55 Hamap MF_00919 Ribosome modulation factor [rmf]. 1 55 27.899 T 29-03-2018 IPR007040 Ribosome modulation factor MC49_RS11290 a58a8d422e2e47ede048a8d3f13e34a1 55 Pfam PF04957 Ribosome modulation factor 1 51 1.5E-28 T 29-03-2018 IPR007040 Ribosome modulation factor MC49_RS11290 a58a8d422e2e47ede048a8d3f13e34a1 55 Gene3D G3DSA:1.10.10.620 3 53 9.8E-23 T 29-03-2018 MC49_RS11290 a58a8d422e2e47ede048a8d3f13e34a1 55 ProDom PD051650 RIBOSOME MODULATION FACTOR E FACTOR-RELATED DIMERIZATION BIOGENESIS RIBOSOMES INVOLVED 70S 1 55 3.0E-18 T 29-03-2018 IPR007040 Ribosome modulation factor MC49_RS14835 399d81a421496a4a921fd346dde7fb7e 259 Gene3D G3DSA:3.40.50.300 14 238 1.1E-49 T 29-03-2018 MC49_RS14835 399d81a421496a4a921fd346dde7fb7e 259 Pfam PF00005 ABC transporter 28 177 3.1E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS14835 399d81a421496a4a921fd346dde7fb7e 259 SMART SM00382 37 222 2.8E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS14835 399d81a421496a4a921fd346dde7fb7e 259 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS14835 399d81a421496a4a921fd346dde7fb7e 259 SUPERFAMILY SSF52540 27 236 6.41E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS17410 c1e65f9609595fcb197d5a57ac057cb9 436 SMART SM00729 153 362 1.6E-24 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MC49_RS17410 c1e65f9609595fcb197d5a57ac057cb9 436 Pfam PF02310 B12 binding domain 33 114 7.9E-7 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 MC49_RS17410 c1e65f9609595fcb197d5a57ac057cb9 436 SUPERFAMILY SSF102114 149 350 1.2E-34 T 29-03-2018 MC49_RS17410 c1e65f9609595fcb197d5a57ac057cb9 436 Pfam PF04055 Radical SAM superfamily 158 317 3.1E-16 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MC49_RS17410 c1e65f9609595fcb197d5a57ac057cb9 436 Gene3D G3DSA:3.40.50.280 29 124 6.8E-5 T 29-03-2018 MC49_RS17410 c1e65f9609595fcb197d5a57ac057cb9 436 Gene3D G3DSA:3.20.20.70 133 379 9.2E-30 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS17820 1bbcf740f07f627da6eaf79e0878a928 165 Pfam PF05565 Siphovirus Gp157 7 165 3.6E-46 T 29-03-2018 IPR008840 Siphovirus Gp157 MC49_RS15445 1bfa8686bb38fa2a20d9237d2d68e2e2 200 SUPERFAMILY SSF54001 22 199 1.77E-47 T 29-03-2018 MC49_RS15445 1bfa8686bb38fa2a20d9237d2d68e2e2 200 Pfam PF05708 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family 24 197 1.8E-43 T 29-03-2018 IPR024453 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family MC49_RS15445 1bfa8686bb38fa2a20d9237d2d68e2e2 200 Gene3D G3DSA:3.90.1720.10 20 200 2.1E-40 T 29-03-2018 MC49_RS00765 201acd51fc83b8b737b5ec73a54ebbc6 193 SUPERFAMILY SSF159594 72 181 1.8E-6 T 29-03-2018 MC49_RS00765 201acd51fc83b8b737b5ec73a54ebbc6 193 Gene3D G3DSA:3.40.50.10610 69 191 2.0E-8 T 29-03-2018 IPR005586 ABC-type transport auxiliary lipoprotein component MC49_RS00765 201acd51fc83b8b737b5ec73a54ebbc6 193 Pfam PF03923 Uncharacterized lipoprotein 34 188 2.8E-50 T 29-03-2018 IPR005619 Uncharacterised protein family, YajG MC49_RS12010 d8f6119e4ab473d641da83f9d5781f00 212 PIRSF PIRSF006324 5 212 4.0E-57 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MC49_RS12010 d8f6119e4ab473d641da83f9d5781f00 212 Pfam PF01810 LysE type translocator 18 209 5.3E-47 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MC49_RS17855 2d7244b4c663efa49dff0564778b9af6 182 Pfam PF01066 CDP-alcohol phosphatidyltransferase 4 71 5.0E-17 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MC49_RS17855 2d7244b4c663efa49dff0564778b9af6 182 PIRSF PIRSF000847 1 182 1.1E-42 T 29-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 MC49_RS17855 2d7244b4c663efa49dff0564778b9af6 182 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 49 71 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MC49_RS17855 2d7244b4c663efa49dff0564778b9af6 182 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 4 180 3.9E-59 T 29-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 MC49_RS19050 47edf510e3bdc9d84203eacd8c36ea54 304 Gene3D G3DSA:1.10.10.10 1 86 1.7E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS19050 47edf510e3bdc9d84203eacd8c36ea54 304 Pfam PF03466 LysR substrate binding domain 87 288 2.1E-41 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS19050 47edf510e3bdc9d84203eacd8c36ea54 304 SUPERFAMILY SSF46785 1 85 8.39E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS19050 47edf510e3bdc9d84203eacd8c36ea54 304 Gene3D G3DSA:3.40.190.10 87 175 1.3E-20 T 29-03-2018 MC49_RS19050 47edf510e3bdc9d84203eacd8c36ea54 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.3E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS19050 47edf510e3bdc9d84203eacd8c36ea54 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.3E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS19050 47edf510e3bdc9d84203eacd8c36ea54 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.3E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS19050 47edf510e3bdc9d84203eacd8c36ea54 304 SUPERFAMILY SSF53850 88 292 1.19E-37 T 29-03-2018 MC49_RS19050 47edf510e3bdc9d84203eacd8c36ea54 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 6.8E-22 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS19050 47edf510e3bdc9d84203eacd8c36ea54 304 Gene3D G3DSA:3.40.190.10 176 265 1.8E-22 T 29-03-2018 MC49_RS03980 fbd638bcfbdf66556ff9424d9699b529 190 Pfam PF01300 Telomere recombination 16 189 1.1E-41 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 MC49_RS03980 fbd638bcfbdf66556ff9424d9699b529 190 Hamap MF_01852 Threonylcarbamoyl-AMP synthase [tsaC]. 7 188 41.184 T 29-03-2018 IPR023535 Threonylcarbamoyl-AMP synthase GO:0002949|GO:0005524 MC49_RS03980 fbd638bcfbdf66556ff9424d9699b529 190 SUPERFAMILY SSF55821 7 187 2.26E-54 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain MC49_RS03980 fbd638bcfbdf66556ff9424d9699b529 190 Gene3D G3DSA:3.90.870.10 1 188 6.3E-52 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain MC49_RS15040 3ca7dd5a9106095811e96c79e483b1ab 208 Hamap MF_00479 Electron transport complex subunit RsxG [rsxG]. 2 194 25.634 T 29-03-2018 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 MC49_RS15040 3ca7dd5a9106095811e96c79e483b1ab 208 PIRSF PIRSF006091 1 202 1.6E-67 T 29-03-2018 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 MC49_RS15040 3ca7dd5a9106095811e96c79e483b1ab 208 Pfam PF04205 FMN-binding domain 100 188 2.7E-17 T 29-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 MC49_RS15040 3ca7dd5a9106095811e96c79e483b1ab 208 TIGRFAM TIGR01947 rnfG: electron transport complex, RnfABCDGE type, G subunit 9 193 3.0E-65 T 29-03-2018 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 MC49_RS15040 3ca7dd5a9106095811e96c79e483b1ab 208 SMART SM00900 100 192 4.4E-33 T 29-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 MC49_RS09275 5aa2dd6486178b45d047250309d0e788 359 Pfam PF11202 Phosphoribosyl transferase (PRTase) 9 248 3.0E-88 T 29-03-2018 IPR011215 Phosphoribosyl transferase MC49_RS09275 5aa2dd6486178b45d047250309d0e788 359 Pfam PF15608 PELOTA RNA binding domain 275 356 1.5E-26 T 29-03-2018 IPR028157 PELOTA RNA-binding domain MC49_RS09275 5aa2dd6486178b45d047250309d0e788 359 PIRSF PIRSF020979 1 358 3.1E-168 T 29-03-2018 IPR011215 Phosphoribosyl transferase MC49_RS02875 78e849e1e4291cbac49b3dcb55b0f46a 102 Pfam PF01381 Helix-turn-helix 16 68 1.4E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS02875 78e849e1e4291cbac49b3dcb55b0f46a 102 SMART SM00530 15 70 5.6E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS02875 78e849e1e4291cbac49b3dcb55b0f46a 102 Gene3D G3DSA:1.10.3100.10 6 100 2.0E-13 T 29-03-2018 IPR027910 YdiL-like domain MC49_RS02875 78e849e1e4291cbac49b3dcb55b0f46a 102 SUPERFAMILY SSF47413 6 71 1.85E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS05690 987bfbb7a9357a559b498e17326f4a57 493 PRINTS PR01806 Virulence factor MviN signature 255 281 1.5E-6 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MC49_RS05690 987bfbb7a9357a559b498e17326f4a57 493 PRINTS PR01806 Virulence factor MviN signature 53 69 1.5E-6 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MC49_RS05690 987bfbb7a9357a559b498e17326f4a57 493 PRINTS PR01806 Virulence factor MviN signature 152 173 1.5E-6 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MC49_RS05690 987bfbb7a9357a559b498e17326f4a57 493 Pfam PF03023 MviN-like protein 29 463 5.0E-38 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MC49_RS15580 2e5cd10376d3cb1cd0293e7488d3e51d 465 PIRSF PIRSF019381 1 465 2.1E-213 T 29-03-2018 IPR007413 Protein of unknown function DUF463, YcjX-like protein MC49_RS15580 2e5cd10376d3cb1cd0293e7488d3e51d 465 Gene3D G3DSA:3.40.50.300 15 430 3.6E-15 T 29-03-2018 MC49_RS15580 2e5cd10376d3cb1cd0293e7488d3e51d 465 Pfam PF04317 YcjX-like family, DUF463 20 464 3.2E-187 T 29-03-2018 IPR007413 Protein of unknown function DUF463, YcjX-like protein MC49_RS14780 e71b52c0fa1726692dbe2437595c1616 355 SUPERFAMILY SSF53474 329 339 2.91E-31 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS14780 e71b52c0fa1726692dbe2437595c1616 355 SUPERFAMILY SSF53474 23 181 2.91E-31 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS14780 e71b52c0fa1726692dbe2437595c1616 355 SUPERFAMILY SSF53474 210 301 2.91E-31 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS14780 e71b52c0fa1726692dbe2437595c1616 355 Gene3D G3DSA:3.40.50.1820 25 347 4.5E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS14780 e71b52c0fa1726692dbe2437595c1616 355 Pfam PF12146 Serine aminopeptidase, S33 63 299 9.7E-8 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 MC49_RS10610 45d154d7af1f41c2624f77a57d28a899 327 SMART SM00729 14 220 1.3E-5 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MC49_RS10610 45d154d7af1f41c2624f77a57d28a899 327 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 5 327 4.5E-105 T 29-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 MC49_RS10610 45d154d7af1f41c2624f77a57d28a899 327 Gene3D G3DSA:3.20.20.70 1 327 4.6E-73 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS10610 45d154d7af1f41c2624f77a57d28a899 327 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 20 31 - T 29-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 MC49_RS10610 45d154d7af1f41c2624f77a57d28a899 327 SUPERFAMILY SSF102114 5 299 4.19E-71 T 29-03-2018 MC49_RS10610 45d154d7af1f41c2624f77a57d28a899 327 Pfam PF13353 4Fe-4S single cluster domain 23 123 1.2E-7 T 29-03-2018 MC49_RS10610 45d154d7af1f41c2624f77a57d28a899 327 Pfam PF06463 Molybdenum Cofactor Synthesis C 184 310 6.4E-38 T 29-03-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 Reactome: R-HSA-947581 MC49_RS10610 45d154d7af1f41c2624f77a57d28a899 327 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 5 327 37.366 T 29-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 MC49_RS10610 45d154d7af1f41c2624f77a57d28a899 327 Pfam PF04055 Radical SAM superfamily 19 179 1.2E-29 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MC49_RS08230 178fe059283c3dc07b0aedbd93ad6bb4 159 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 2 156 2.1E-70 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MC49_RS08230 178fe059283c3dc07b0aedbd93ad6bb4 159 Pfam PF02542 YgbB family 1 154 6.2E-66 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MC49_RS08230 178fe059283c3dc07b0aedbd93ad6bb4 159 Gene3D G3DSA:3.30.1330.50 1 158 8.3E-73 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MC49_RS08230 178fe059283c3dc07b0aedbd93ad6bb4 159 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 35 50 - T 29-03-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MC49_RS08230 178fe059283c3dc07b0aedbd93ad6bb4 159 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 1 156 36.365 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MC49_RS08230 178fe059283c3dc07b0aedbd93ad6bb4 159 SUPERFAMILY SSF69765 1 156 1.06E-65 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MC49_RS12940 8130df451572fd86f8749471c1346c2d 263 SUPERFAMILY SSF46785 28 101 4.3E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS12940 8130df451572fd86f8749471c1346c2d 263 Gene3D G3DSA:1.10.10.10 29 134 2.4E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS12940 8130df451572fd86f8749471c1346c2d 263 Pfam PF04492 Bacteriophage replication protein O 17 111 9.8E-34 T 29-03-2018 IPR006497 Bacteriophage lambda, GpO, N-terminal GO:0006260 MC49_RS12940 8130df451572fd86f8749471c1346c2d 263 TIGRFAM TIGR01610 phage_O_Nterm: phage replication protein O, N-terminal domain 19 111 3.5E-31 T 29-03-2018 IPR006497 Bacteriophage lambda, GpO, N-terminal GO:0006260 MC49_RS16130 455367a0507ca54524c8938e4117a19c 384 Gene3D G3DSA:1.20.1250.20 204 383 9.4E-15 T 29-03-2018 MC49_RS16130 455367a0507ca54524c8938e4117a19c 384 SUPERFAMILY SSF103473 23 380 8.37E-33 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS16130 455367a0507ca54524c8938e4117a19c 384 Gene3D G3DSA:1.20.1250.20 20 188 3.9E-13 T 29-03-2018 MC49_RS07945 12bb85e2f1ed2ca9df46d4f898095bd5 403 Gene3D G3DSA:3.40.640.10 28 279 8.7E-60 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS07945 12bb85e2f1ed2ca9df46d4f898095bd5 403 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 214 233 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site MC49_RS07945 12bb85e2f1ed2ca9df46d4f898095bd5 403 SUPERFAMILY SSF53383 6 395 7.45E-107 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS07945 12bb85e2f1ed2ca9df46d4f898095bd5 403 Gene3D G3DSA:3.90.1150.10 280 396 1.2E-37 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS07945 12bb85e2f1ed2ca9df46d4f898095bd5 403 TIGRFAM TIGR03392 FeS_syn_CsdA: cysteine desulfurase, catalytic subunit CsdA 4 402 1.7E-184 T 29-03-2018 IPR022471 Cysteine desulphurase, catalytic subunit, CsdA GO:0016226|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 MC49_RS07945 12bb85e2f1ed2ca9df46d4f898095bd5 403 Pfam PF00266 Aminotransferase class-V 21 389 1.9E-125 T 29-03-2018 IPR000192 Aminotransferase class V domain MC49_RS16570 75c06470617042f6dc36248334b3426c 151 Pfam PF04217 Protein of unknown function, DUF412 12 149 3.4E-55 T 29-03-2018 IPR007334 Uncharacterised protein family UPF0208 MC49_RS16570 75c06470617042f6dc36248334b3426c 151 Hamap MF_01101 UPF0208 membrane protein YfbV [yfbV]. 9 151 34.76 T 29-03-2018 IPR007334 Uncharacterised protein family UPF0208 MC49_RS12915 66aca46c4553c793a4fcc7e18d684eb9 65 Pfam PF10965 Protein of unknown function (DUF2767) 5 61 1.6E-4 T 29-03-2018 IPR024493 Fumarase D MC49_RS08705 a52dc35023d1e55eab1407d38dc0f20e 212 Gene3D G3DSA:3.90.550.10 24 203 9.8E-22 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MC49_RS08705 a52dc35023d1e55eab1407d38dc0f20e 212 SUPERFAMILY SSF53448 28 206 4.16E-19 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases MC49_RS08705 a52dc35023d1e55eab1407d38dc0f20e 212 Pfam PF12804 MobA-like NTP transferase domain 31 183 3.9E-26 T 29-03-2018 IPR025877 MobA-like NTP transferase MC49_RS03095 94f8d70afe10778edf4d6169e3d22b01 373 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 81 93 - T 29-03-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-5334118 MC49_RS03095 94f8d70afe10778edf4d6169e3d22b01 373 Gene3D G3DSA:3.40.50.150 11 229 1.2E-62 T 29-03-2018 MC49_RS03095 94f8d70afe10778edf4d6169e3d22b01 373 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 189 202 1.6E-17 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 MC49_RS03095 94f8d70afe10778edf4d6169e3d22b01 373 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 120 134 1.6E-17 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 MC49_RS03095 94f8d70afe10778edf4d6169e3d22b01 373 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 21 37 1.6E-17 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 MC49_RS03095 94f8d70afe10778edf4d6169e3d22b01 373 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 172 359 3.7E-34 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 MC49_RS03095 94f8d70afe10778edf4d6169e3d22b01 373 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 22 148 6.7E-57 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 MC49_RS03095 94f8d70afe10778edf4d6169e3d22b01 373 SUPERFAMILY SSF53335 20 361 3.93E-86 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS03095 94f8d70afe10778edf4d6169e3d22b01 373 Pfam PF00145 C-5 cytosine-specific DNA methylase 172 359 1.2E-36 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS03095 94f8d70afe10778edf4d6169e3d22b01 373 Pfam PF00145 C-5 cytosine-specific DNA methylase 20 148 1.9E-54 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS03095 94f8d70afe10778edf4d6169e3d22b01 373 Gene3D G3DSA:3.90.120.10 230 347 8.5E-22 T 29-03-2018 MC49_RS15325 c9887ea676214fa04a20ae8347e6108a 241 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS15325 c9887ea676214fa04a20ae8347e6108a 241 Pfam PF00005 ABC transporter 29 173 7.3E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS15325 c9887ea676214fa04a20ae8347e6108a 241 Gene3D G3DSA:3.40.50.300 5 238 7.3E-61 T 29-03-2018 MC49_RS15325 c9887ea676214fa04a20ae8347e6108a 241 SUPERFAMILY SSF52540 9 230 9.06E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS15325 c9887ea676214fa04a20ae8347e6108a 241 SMART SM00382 34 222 1.6E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS03435 8467edd77742f529d6c6d4b25357c46d 480 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 26 469 2.3E-155 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MC49_RS03435 8467edd77742f529d6c6d4b25357c46d 480 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 61 80 1.3E-37 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MC49_RS03435 8467edd77742f529d6c6d4b25357c46d 480 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 427 440 1.3E-37 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MC49_RS03435 8467edd77742f529d6c6d4b25357c46d 480 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 363 377 1.3E-37 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MC49_RS03435 8467edd77742f529d6c6d4b25357c46d 480 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 348 362 1.3E-37 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MC49_RS03435 8467edd77742f529d6c6d4b25357c46d 480 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 289 311 1.3E-37 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MC49_RS03435 8467edd77742f529d6c6d4b25357c46d 480 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 48 449 1.3E-160 T 29-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MC49_RS03435 8467edd77742f529d6c6d4b25357c46d 480 Gene3D G3DSA:3.40.710.10 23 480 4.0E-40 T 29-03-2018 MC49_RS03435 8467edd77742f529d6c6d4b25357c46d 480 SUPERFAMILY SSF56601 26 474 1.98E-100 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MC49_RS14545 a4978eedc7e70d4d48f448ea84e424cb 450 SUPERFAMILY SSF53067 85 202 8.2E-27 T 29-03-2018 MC49_RS14545 a4978eedc7e70d4d48f448ea84e424cb 450 SUPERFAMILY SSF53067 1 44 8.2E-27 T 29-03-2018 MC49_RS14545 a4978eedc7e70d4d48f448ea84e424cb 450 SUPERFAMILY SSF53067 208 276 8.43E-31 T 29-03-2018 MC49_RS14545 a4978eedc7e70d4d48f448ea84e424cb 450 SUPERFAMILY SSF53067 328 446 8.43E-31 T 29-03-2018 MC49_RS14545 a4978eedc7e70d4d48f448ea84e424cb 450 Pfam PF00012 Hsp70 protein 129 232 3.9E-10 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MC49_RS14545 a4978eedc7e70d4d48f448ea84e424cb 450 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 213 226 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MC49_RS14545 a4978eedc7e70d4d48f448ea84e424cb 450 Gene3D G3DSA:3.30.420.40 218 429 2.1E-29 T 29-03-2018 MC49_RS14545 a4978eedc7e70d4d48f448ea84e424cb 450 Gene3D G3DSA:3.30.420.40 1 217 1.2E-34 T 29-03-2018 MC49_RS17035 3719b799e2fa2af21d9eff96a8ee7d74 182 Pfam PF05728 Uncharacterised protein family (UPF0227) 1 176 7.8E-61 T 29-03-2018 IPR008886 Uncharacterised protein family UPF0227/Esterase YqiA MC49_RS17035 3719b799e2fa2af21d9eff96a8ee7d74 182 SUPERFAMILY SSF53474 2 175 2.17E-5 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS06325 af992d4d33580aee148114fb3d66c6b1 188 Gene3D G3DSA:3.40.50.360 1 178 9.4E-32 T 29-03-2018 IPR029039 Flavoprotein-like domain MC49_RS06325 af992d4d33580aee148114fb3d66c6b1 188 SUPERFAMILY SSF52218 6 176 2.87E-44 T 29-03-2018 IPR029039 Flavoprotein-like domain MC49_RS06325 af992d4d33580aee148114fb3d66c6b1 188 Hamap MF_01415 Glutathione-regulated potassium-efflux system ancillary protein KefG [kefG]. 1 182 47.301 T 29-03-2018 IPR023947 Glutathione-regulated potassium-efflux system ancillary protein KefG GO:0006813 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 MC49_RS06325 af992d4d33580aee148114fb3d66c6b1 188 Pfam PF02525 Flavodoxin-like fold 6 170 7.7E-43 T 29-03-2018 IPR003680 Flavodoxin-like fold MC49_RS02450 f55952d1d8eee4251db230b2c0b70289 171 SUPERFAMILY SSF49401 25 170 2.98E-25 T 29-03-2018 IPR008966 Adhesion domain MC49_RS02450 f55952d1d8eee4251db230b2c0b70289 171 Gene3D G3DSA:2.60.40.1090 23 171 1.7E-17 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS05845 5303d9f3584748058847a2ffa392fa02 80 Hamap MF_01196 Cell division protein ZapB [zapB]. 1 79 17.897 T 29-03-2018 IPR009252 Cell division protein ZapB GO:0005737|GO:0043093|GO:0090529 MC49_RS05845 5303d9f3584748058847a2ffa392fa02 80 Gene3D G3DSA:1.20.5.370 50 80 5.3E-12 T 29-03-2018 MC49_RS05845 5303d9f3584748058847a2ffa392fa02 80 Gene3D G3DSA:1.20.5.370 13 49 1.9E-13 T 29-03-2018 MC49_RS05845 5303d9f3584748058847a2ffa392fa02 80 Pfam PF06005 Cell division protein ZapB 1 77 3.5E-28 T 29-03-2018 IPR009252 Cell division protein ZapB GO:0005737|GO:0043093|GO:0090529 MC49_RS02790 c7318c1e72a5751a52d0f94b824db811 187 Pfam PF09482 Bacterial type III secretion apparatus protein (OrgA_MxiK) 12 161 6.7E-18 T 29-03-2018 IPR013388 Type III secretion apparatus protein OrgA/MxiK GO:0009405 MC49_RS12265 73f0fd06403ecb0252f17373ad923352 293 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 30 48 - T 29-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 MC49_RS12265 73f0fd06403ecb0252f17373ad923352 293 TIGRFAM TIGR01136 cysKM: cysteine synthase 5 292 3.4E-120 T 29-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 MC49_RS12265 73f0fd06403ecb0252f17373ad923352 293 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 5 281 4.9E-70 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MC49_RS12265 73f0fd06403ecb0252f17373ad923352 293 Gene3D G3DSA:3.40.50.1100 130 293 1.7E-49 T 29-03-2018 MC49_RS12265 73f0fd06403ecb0252f17373ad923352 293 Gene3D G3DSA:3.40.50.1100 20 129 8.7E-36 T 29-03-2018 MC49_RS12265 73f0fd06403ecb0252f17373ad923352 293 SUPERFAMILY SSF53686 3 289 4.71E-95 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MC49_RS12265 73f0fd06403ecb0252f17373ad923352 293 TIGRFAM TIGR01138 cysM: cysteine synthase B 4 292 8.1E-144 T 29-03-2018 IPR005858 Cysteine synthase CysM GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 MC49_RS04755 16b06e8deac56f02d8694c7e75f5ced0 539 PIRSF PIRSF006294 2 539 9.6E-228 T 29-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 MC49_RS04755 16b06e8deac56f02d8694c7e75f5ced0 539 Pfam PF01293 Phosphoenolpyruvate carboxykinase 21 490 3.0E-210 T 29-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 MC49_RS04755 16b06e8deac56f02d8694c7e75f5ced0 539 SUPERFAMILY SSF68923 9 226 4.36E-89 T 29-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 MC49_RS04755 16b06e8deac56f02d8694c7e75f5ced0 539 ProSitePatterns PS00532 Phosphoenolpyruvate carboxykinase (ATP) signature. 264 279 - T 29-03-2018 IPR015994 Phosphoenolpyruvate carboxykinase (ATP), conserved site GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 MC49_RS04755 16b06e8deac56f02d8694c7e75f5ced0 539 TIGRFAM TIGR00224 pckA: phosphoenolpyruvate carboxykinase (ATP) 8 538 2.5E-277 T 29-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 MC49_RS04755 16b06e8deac56f02d8694c7e75f5ced0 539 SUPERFAMILY SSF53795 228 538 2.52E-130 T 29-03-2018 MC49_RS04755 16b06e8deac56f02d8694c7e75f5ced0 539 Hamap MF_00453 Phosphoenolpyruvate carboxykinase (ATP) [pckA]. 15 537 54.584 T 29-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 MC49_RS04755 16b06e8deac56f02d8694c7e75f5ced0 539 Gene3D G3DSA:3.90.228.20 227 306 1.7E-28 T 29-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 MC49_RS04755 16b06e8deac56f02d8694c7e75f5ced0 539 Gene3D G3DSA:3.90.228.20 307 537 4.0E-93 T 29-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 MC49_RS04755 16b06e8deac56f02d8694c7e75f5ced0 539 Gene3D G3DSA:3.40.449.10 22 226 5.5E-76 T 29-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 MC49_RS07785 6e2b953d6e4f3dd4d7421b4fa9a66aea 125 Pfam PF04379 ApaG domain 18 102 2.7E-35 T 29-03-2018 IPR007474 ApaG domain MC49_RS07785 6e2b953d6e4f3dd4d7421b4fa9a66aea 125 Gene3D G3DSA:2.60.40.1470 3 125 1.5E-44 T 29-03-2018 IPR007474 ApaG domain MC49_RS07785 6e2b953d6e4f3dd4d7421b4fa9a66aea 125 Hamap MF_00791 Protein ApaG [apaG]. 1 125 32.261 T 29-03-2018 IPR023065 Uncharacterised protein family ApaG MC49_RS07785 6e2b953d6e4f3dd4d7421b4fa9a66aea 125 SUPERFAMILY SSF110069 5 125 1.7E-47 T 29-03-2018 IPR007474 ApaG domain MC49_RS08655 7c737fb71923b927a10d361b9de424b4 302 Pfam PF01497 Periplasmic binding protein 38 280 1.7E-24 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 MC49_RS08655 7c737fb71923b927a10d361b9de424b4 302 SUPERFAMILY SSF53807 34 299 9.81E-39 T 29-03-2018 MC49_RS08655 7c737fb71923b927a10d361b9de424b4 302 Gene3D G3DSA:3.40.50.1980 29 144 6.0E-17 T 29-03-2018 MC49_RS08655 7c737fb71923b927a10d361b9de424b4 302 Gene3D G3DSA:3.40.50.1980 145 302 7.3E-36 T 29-03-2018 MC49_RS00555 6ae52184b599f443558c0cacb2dad198 891 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 526 606 2.9E-26 T 29-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 MC49_RS07125 fd514540a7d94f2bfccad28dd8acb327 251 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 4 241 17.929 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MC49_RS07125 fd514540a7d94f2bfccad28dd8acb327 251 Pfam PF00902 Sec-independent protein translocase protein (TatC) 12 221 6.8E-64 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MC49_RS07125 fd514540a7d94f2bfccad28dd8acb327 251 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 103 129 1.1E-48 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MC49_RS07125 fd514540a7d94f2bfccad28dd8acb327 251 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 154 182 1.1E-48 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MC49_RS07125 fd514540a7d94f2bfccad28dd8acb327 251 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 8 35 1.1E-48 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MC49_RS07125 fd514540a7d94f2bfccad28dd8acb327 251 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 85 103 1.1E-48 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MC49_RS07125 fd514540a7d94f2bfccad28dd8acb327 251 ProSitePatterns PS01218 TatC family signature. 154 173 - T 29-03-2018 IPR019820 Sec-independent periplasmic protein translocase, conserved site MC49_RS07125 fd514540a7d94f2bfccad28dd8acb327 251 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 9 226 2.7E-76 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MC49_RS17295 65a0768ab6ee1a5169952e731f1d6406 75 Hamap MF_00816 UPF0352 protein YejL [yejL]. 1 71 22.813 T 29-03-2018 IPR009857 Uncharacterised protein family UPF0352 MC49_RS17295 65a0768ab6ee1a5169952e731f1d6406 75 PIRSF PIRSF006188 1 72 1.1E-33 T 29-03-2018 IPR009857 Uncharacterised protein family UPF0352 MC49_RS17295 65a0768ab6ee1a5169952e731f1d6406 75 Pfam PF07208 Protein of unknown function (DUF1414) 26 69 1.5E-23 T 29-03-2018 IPR009857 Uncharacterised protein family UPF0352 MC49_RS17295 65a0768ab6ee1a5169952e731f1d6406 75 ProDom PD027794 UPF0352 YEJL NTHI1007 CPS_2611 VF1649 VV1166 HD1515 VP2129 YPO1261/Y2923/YP0880 ECA2748 1 69 5.0E-29 T 29-03-2018 IPR009857 Uncharacterised protein family UPF0352 MC49_RS17295 65a0768ab6ee1a5169952e731f1d6406 75 Gene3D G3DSA:1.10.3390.10 2 71 2.3E-34 T 29-03-2018 IPR023202 YejL-like domain MC49_RS17295 65a0768ab6ee1a5169952e731f1d6406 75 SUPERFAMILY SSF158651 1 75 5.63E-31 T 29-03-2018 IPR023202 YejL-like domain MC49_RS17750 49a9c8e9819c4a9e4dec6ee7da0d9705 208 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 76 82 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MC49_RS17750 49a9c8e9819c4a9e4dec6ee7da0d9705 208 TIGRFAM TIGR01712 phage_N6A_met: phage N-6-adenine-methyltransferase 7 190 1.8E-59 T 29-03-2018 IPR008593 DNA N-6-adenine-methyltransferase GO:0003677|GO:0009007|GO:0032775 MC49_RS17750 49a9c8e9819c4a9e4dec6ee7da0d9705 208 Pfam PF05869 DNA N-6-adenine-methyltransferase (Dam) 10 193 5.2E-58 T 29-03-2018 IPR008593 DNA N-6-adenine-methyltransferase GO:0003677|GO:0009007|GO:0032775 MC49_RS00710 5f19a57299e3be1fcd7b84debbbea99d 346 SUPERFAMILY SSF53686 20 333 3.14E-68 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MC49_RS00710 5f19a57299e3be1fcd7b84debbbea99d 346 Gene3D G3DSA:3.40.50.1100 141 329 1.2E-38 T 29-03-2018 MC49_RS00710 5f19a57299e3be1fcd7b84debbbea99d 346 Gene3D G3DSA:3.40.50.1100 32 140 4.6E-22 T 29-03-2018 MC49_RS00710 5f19a57299e3be1fcd7b84debbbea99d 346 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 33 313 3.5E-43 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MC49_RS18470 780be466d3d6263adc18ef9d5d8feae0 109 SUPERFAMILY SSF102829 6 95 8.37E-24 T 29-03-2018 IPR007838 Cell division protein ZapA-like MC49_RS18470 780be466d3d6263adc18ef9d5d8feae0 109 Pfam PF05164 Cell division protein ZapA 6 90 2.8E-18 T 29-03-2018 IPR007838 Cell division protein ZapA-like MC49_RS12330 800359345518ec745620f5b7441bb179 313 PIRSF PIRSF026649 2 306 8.6E-103 T 29-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 MC49_RS12330 800359345518ec745620f5b7441bb179 313 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 5 297 7.1E-104 T 29-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 MC49_RS12330 800359345518ec745620f5b7441bb179 313 Hamap MF_01942 Lipid A biosynthesis lauroyltransferase [lpxL]. 4 306 53.531 T 29-03-2018 IPR011920 Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase GO:0009245|GO:0016021|GO:0016740 KEGG: 00600+2.3.1.24 MC49_RS12330 800359345518ec745620f5b7441bb179 313 TIGRFAM TIGR02207 lipid_A_htrB: lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase 5 306 2.2E-145 T 29-03-2018 IPR011920 Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase GO:0009245|GO:0016021|GO:0016740 KEGG: 00600+2.3.1.24 MC49_RS18195 64fa45d15964da742bebd06ffbe3f440 488 Pfam PF13520 Amino acid permease 10 439 6.1E-30 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MC49_RS18195 64fa45d15964da742bebd06ffbe3f440 488 PIRSF PIRSF006060 1 476 1.3E-51 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MC49_RS18610 fb4f1fc44299f254c9ebea62b4303406 180 Pfam PF06558 Secretion monitor precursor protein (SecM) 31 177 8.1E-44 T 29-03-2018 IPR009502 Secretion monitor GO:0045182 MC49_RS18610 fb4f1fc44299f254c9ebea62b4303406 180 ProDom PD089227 MONITOR PERIPLASMIC SECRETION PRECURSOR SIGNAL YACA 11 176 4.0E-31 T 29-03-2018 IPR009502 Secretion monitor GO:0045182 MC49_RS18610 fb4f1fc44299f254c9ebea62b4303406 180 Hamap MF_01332 Secretion monitor [secM]. 8 180 27.301 T 29-03-2018 IPR009502 Secretion monitor GO:0045182 MC49_RS08615 0f41d025e0c323772245aeea5c644f0b 219 SMART SM00877 35 110 5.0E-6 T 29-03-2018 IPR000249 Microcompartment protein, bacteria MC49_RS08615 0f41d025e0c323772245aeea5c644f0b 219 SMART SM00877 146 219 2.5E-6 T 29-03-2018 IPR000249 Microcompartment protein, bacteria MC49_RS08615 0f41d025e0c323772245aeea5c644f0b 219 SUPERFAMILY SSF143414 159 211 7.06E-6 T 29-03-2018 MC49_RS08615 0f41d025e0c323772245aeea5c644f0b 219 Pfam PF00936 BMC domain 162 208 2.1E-6 T 29-03-2018 IPR000249 Microcompartment protein, bacteria MC49_RS08615 0f41d025e0c323772245aeea5c644f0b 219 Pfam PF00936 BMC domain 36 107 4.1E-12 T 29-03-2018 IPR000249 Microcompartment protein, bacteria MC49_RS08615 0f41d025e0c323772245aeea5c644f0b 219 SUPERFAMILY SSF143414 35 108 9.68E-5 T 29-03-2018 MC49_RS08615 0f41d025e0c323772245aeea5c644f0b 219 TIGRFAM TIGR04502 microcomp_EutL: microcompartment protein EutL 6 217 5.3E-99 T 29-03-2018 IPR030983 Ethanolamine utilization protein EutL GO:0005198 MC49_RS08615 0f41d025e0c323772245aeea5c644f0b 219 PIRSF PIRSF012290 1 219 1.2E-78 T 29-03-2018 IPR009193 Polyhedral organelle shell protein, EutL/PduB type GO:0009605 MC49_RS08615 0f41d025e0c323772245aeea5c644f0b 219 Gene3D G3DSA:2.40.50.100 39 200 9.2E-4 T 29-03-2018 MC49_RS01800 d72cc12e15bb5941900948390ad05472 256 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 233 253 3.4E-10 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal MC49_RS01800 d72cc12e15bb5941900948390ad05472 256 Gene3D G3DSA:3.40.50.300 1 254 8.4E-58 T 29-03-2018 MC49_RS01800 d72cc12e15bb5941900948390ad05472 256 Pfam PF00005 ABC transporter 21 181 2.1E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS01800 d72cc12e15bb5941900948390ad05472 256 SUPERFAMILY SSF52540 4 253 6.3E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS01800 d72cc12e15bb5941900948390ad05472 256 SMART SM00382 30 230 1.1E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS01800 d72cc12e15bb5941900948390ad05472 256 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS06865 ce43058dafaa840713c7d7c738eb3461 92 SUPERFAMILY SSF69279 2 91 6.12E-26 T 29-03-2018 MC49_RS06865 ce43058dafaa840713c7d7c738eb3461 92 Pfam PF13856 ATP-binding sugar transporter from pro-phage 3 87 8.8E-7 T 29-03-2018 IPR025601 ATP-binding sugar transporter-like protein MC49_RS06865 ce43058dafaa840713c7d7c738eb3461 92 Gene3D G3DSA:2.40.10.210 24 90 8.3E-25 T 29-03-2018 MC49_RS01060 6f33851d6122532acc159bdc05061786 245 TIGRFAM TIGR02780 TrbJ_Ti: P-type conjugative transfer protein TrbJ 4 243 2.3E-73 T 29-03-2018 IPR014147 Type IV conjugative transfer protein TrbJ MC49_RS01060 6f33851d6122532acc159bdc05061786 245 Gene3D G3DSA:1.20.58.430 29 220 4.2E-32 T 29-03-2018 MC49_RS01060 6f33851d6122532acc159bdc05061786 245 SUPERFAMILY SSF101082 31 207 2.09E-5 T 29-03-2018 IPR023220 Type IV secretion system, VirB5-domain MC49_RS17695 7523d871ad3b758d29bd73dceaab5df7 158 SUPERFAMILY SSF53955 8 157 7.16E-53 T 29-03-2018 IPR023346 Lysozyme-like domain MC49_RS17695 7523d871ad3b758d29bd73dceaab5df7 158 Pfam PF00959 Phage lysozyme 43 148 5.4E-25 T 29-03-2018 IPR002196 Glycoside hydrolase, family 24 GO:0003796|GO:0009253|GO:0016998 MC49_RS17695 7523d871ad3b758d29bd73dceaab5df7 158 Gene3D G3DSA:1.10.530.40 1 158 2.7E-50 T 29-03-2018 IPR023347 Lysozyme domain GO:0003796 MC49_RS03280 ce908282bb5f269c2cb1844a85883479 151 SUPERFAMILY SSF50475 6 139 1.2E-16 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MC49_RS03280 ce908282bb5f269c2cb1844a85883479 151 Hamap MF_00764 UPF0306 protein YhbP [yhbP]. 4 141 31.737 T 29-03-2018 IPR011194 Uncharacterised protein family UPF0306 MC49_RS03280 ce908282bb5f269c2cb1844a85883479 151 PIRSF PIRSF009554 1 144 8.1E-56 T 29-03-2018 IPR011194 Uncharacterised protein family UPF0306 MC49_RS03280 ce908282bb5f269c2cb1844a85883479 151 Gene3D G3DSA:2.30.110.10 2 144 6.2E-14 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 MC49_RS02345 7f8517afe401aa7fde04b0e648b7d98b 109 Pfam PF01381 Helix-turn-helix 24 75 2.9E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS02345 7f8517afe401aa7fde04b0e648b7d98b 109 Gene3D G3DSA:1.10.260.40 6 82 9.2E-15 T 29-03-2018 MC49_RS02345 7f8517afe401aa7fde04b0e648b7d98b 109 SUPERFAMILY SSF47413 11 82 4.35E-19 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS02345 7f8517afe401aa7fde04b0e648b7d98b 109 SMART SM00530 20 75 9.4E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS13770 35617dbe79b39551519c40dec28e8bea 262 Pfam PF06738 Putative threonine/serine exporter 17 255 9.1E-67 T 29-03-2018 IPR010619 Putative threonine/serine exporter MC49_RS15225 49f23ae11cabb5eeb4d915bd939fcf97 146 Pfam PF03061 Thioesterase superfamily 26 98 1.5E-20 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MC49_RS15225 49f23ae11cabb5eeb4d915bd939fcf97 146 SUPERFAMILY SSF54637 8 133 6.13E-39 T 29-03-2018 IPR029069 HotDog domain MC49_RS15225 49f23ae11cabb5eeb4d915bd939fcf97 146 Gene3D G3DSA:3.10.129.10 3 137 1.7E-35 T 29-03-2018 MC49_RS17420 dd06b6a9a80175acbaeae29331d365de 448 Pfam PF04055 Radical SAM superfamily 161 316 1.6E-11 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MC49_RS17420 dd06b6a9a80175acbaeae29331d365de 448 Gene3D G3DSA:3.20.20.70 137 407 3.4E-24 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS17420 dd06b6a9a80175acbaeae29331d365de 448 Gene3D G3DSA:3.40.50.280 34 136 7.9E-6 T 29-03-2018 MC49_RS17420 dd06b6a9a80175acbaeae29331d365de 448 SUPERFAMILY SSF102114 157 351 1.83E-27 T 29-03-2018 MC49_RS17420 dd06b6a9a80175acbaeae29331d365de 448 SMART SM00729 157 359 5.8E-20 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 MC49_RS17420 dd06b6a9a80175acbaeae29331d365de 448 Pfam PF02310 B12 binding domain 55 119 8.1E-7 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 MC49_RS11315 742c32d0071709bec31d1a6d72ba242c 168 SUPERFAMILY SSF52540 29 143 2.18E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS11315 742c32d0071709bec31d1a6d72ba242c 168 Gene3D G3DSA:3.40.50.300 28 144 7.3E-19 T 29-03-2018 MC49_RS11315 742c32d0071709bec31d1a6d72ba242c 168 Hamap MF_01179 Cell division inhibitor SulA [sulA]. 1 168 31.777 T 29-03-2018 IPR004596 Cell division suppressor protein, SulA GO:0009432|GO:0051782 MC49_RS11315 742c32d0071709bec31d1a6d72ba242c 168 PIRSF PIRSF003093 3 168 1.1E-57 T 29-03-2018 IPR004596 Cell division suppressor protein, SulA GO:0009432|GO:0051782 MC49_RS11315 742c32d0071709bec31d1a6d72ba242c 168 Pfam PF03846 Cell division inhibitor SulA 21 117 9.0E-38 T 29-03-2018 IPR004596 Cell division suppressor protein, SulA GO:0009432|GO:0051782 MC49_RS03270 f7327044439e568cd498bb31f66a0360 712 Pfam PF03477 ATP cone domain 4 89 3.7E-20 T 29-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 MC49_RS03270 f7327044439e568cd498bb31f66a0360 712 Gene3D G3DSA:3.20.70.20 121 687 2.7E-207 T 29-03-2018 MC49_RS03270 f7327044439e568cd498bb31f66a0360 712 ProSitePatterns PS00850 Glycine radical domain signature. 676 684 - T 29-03-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site MC49_RS03270 f7327044439e568cd498bb31f66a0360 712 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 116 705 1.4E-183 T 29-03-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 MC49_RS03270 f7327044439e568cd498bb31f66a0360 712 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 115 705 3.3E-204 T 29-03-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 MC49_RS03270 f7327044439e568cd498bb31f66a0360 712 SUPERFAMILY SSF51998 121 687 2.17E-195 T 29-03-2018 MC49_RS15190 daa58cba7d4dea91eafeaf706f6e7cc2 258 Pfam PF06790 Uncharacterised protein family (UPF0259) 1 246 1.7E-54 T 29-03-2018 IPR009627 Uncharacterised protein family UPF0259 MC49_RS15190 daa58cba7d4dea91eafeaf706f6e7cc2 258 Hamap MF_01067 UPF0259 membrane protein YciC [yciC]. 1 249 19.109 T 29-03-2018 IPR009627 Uncharacterised protein family UPF0259 MC49_RS04080 7602276e11d96de62a494cb093203ddb 117 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 1 117 7.3E-44 T 29-03-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS04080 7602276e11d96de62a494cb093203ddb 117 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 2 117 26.08 T 29-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS04080 7602276e11d96de62a494cb093203ddb 117 SUPERFAMILY SSF53137 3 115 2.83E-53 T 29-03-2018 MC49_RS04080 7602276e11d96de62a494cb093203ddb 117 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 3 117 1.4E-45 T 29-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS04080 7602276e11d96de62a494cb093203ddb 117 Gene3D G3DSA:3.30.420.100 1 117 4.2E-37 T 29-03-2018 MC49_RS13995 a6ecd0128b67305a959c64178c456df2 511 PIRSF PIRSF002869 1 511 7.2E-174 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MC49_RS13995 a6ecd0128b67305a959c64178c456df2 511 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 2 502 8.0E-164 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MC49_RS13995 a6ecd0128b67305a959c64178c456df2 511 Pfam PF03023 MviN-like protein 28 478 1.7E-151 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MC49_RS13995 a6ecd0128b67305a959c64178c456df2 511 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 3 467 20.218 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MC49_RS13995 a6ecd0128b67305a959c64178c456df2 511 PRINTS PR01806 Virulence factor MviN signature 33 52 1.3E-84 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MC49_RS13995 a6ecd0128b67305a959c64178c456df2 511 PRINTS PR01806 Virulence factor MviN signature 357 376 1.3E-84 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MC49_RS13995 a6ecd0128b67305a959c64178c456df2 511 PRINTS PR01806 Virulence factor MviN signature 133 157 1.3E-84 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MC49_RS13995 a6ecd0128b67305a959c64178c456df2 511 PRINTS PR01806 Virulence factor MviN signature 157 178 1.3E-84 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MC49_RS13995 a6ecd0128b67305a959c64178c456df2 511 PRINTS PR01806 Virulence factor MviN signature 52 68 1.3E-84 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MC49_RS13995 a6ecd0128b67305a959c64178c456df2 511 PRINTS PR01806 Virulence factor MviN signature 409 426 1.3E-84 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MC49_RS13995 a6ecd0128b67305a959c64178c456df2 511 PRINTS PR01806 Virulence factor MviN signature 259 285 1.3E-84 T 29-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MC49_RS01075 55b35294d272ac3c853e07a5a47e9b76 127 Pfam PF04956 TrbC/VIRB2 family 30 117 5.0E-24 T 29-03-2018 IPR007039 Conjugal transfer TrbC/type IV secretion VirB2 MC49_RS12680 2cc2396e9587dac9a69f15f408aa2027 132 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 4 121 17.431 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 MC49_RS12680 2cc2396e9587dac9a69f15f408aa2027 132 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 6 116 3.1E-18 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 MC49_RS04785 206bc79d30fdb1b8c88dffc0ac573b81 145 SUPERFAMILY SSF52402 3 139 6.28E-32 T 29-03-2018 MC49_RS04785 206bc79d30fdb1b8c88dffc0ac573b81 145 PIRSF PIRSF006276 1 141 1.6E-53 T 29-03-2018 IPR006015 Universal stress protein A MC49_RS04785 206bc79d30fdb1b8c88dffc0ac573b81 145 Pfam PF00582 Universal stress protein family 3 138 5.5E-21 T 29-03-2018 IPR006016 UspA GO:0006950 MC49_RS04785 206bc79d30fdb1b8c88dffc0ac573b81 145 Gene3D G3DSA:3.40.50.620 2 142 9.5E-26 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS14305 125e83326b96d728ad8a379e4167362c 679 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 39 - T 29-03-2018 IPR010916 TonB box, conserved site MC49_RS14305 125e83326b96d728ad8a379e4167362c 679 Pfam PF07715 TonB-dependent Receptor Plug Domain 71 163 4.8E-8 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MC49_RS14305 125e83326b96d728ad8a379e4167362c 679 SUPERFAMILY SSF56935 27 679 6.8E-83 T 29-03-2018 MC49_RS14305 125e83326b96d728ad8a379e4167362c 679 Gene3D G3DSA:2.40.170.20 170 679 8.4E-60 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MC49_RS14305 125e83326b96d728ad8a379e4167362c 679 Gene3D G3DSA:2.170.130.10 22 169 8.6E-12 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MC49_RS14305 125e83326b96d728ad8a379e4167362c 679 Pfam PF00593 TonB dependent receptor 192 678 3.2E-33 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MC49_RS14410 33c22ae305549df8633920efbf4fdf63 390 Gene3D G3DSA:3.40.640.10 43 272 8.3E-36 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS14410 33c22ae305549df8633920efbf4fdf63 390 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 6 387 8.4E-113 T 29-03-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 MC49_RS14410 33c22ae305549df8633920efbf4fdf63 390 SUPERFAMILY SSF53383 2 388 1.73E-84 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS14410 33c22ae305549df8633920efbf4fdf63 390 Pfam PF00155 Aminotransferase class I and II 32 380 2.0E-52 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MC49_RS14410 33c22ae305549df8633920efbf4fdf63 390 Gene3D G3DSA:3.90.1150.10 273 386 8.0E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS02745 2ad49cd4c2badd14b8fbf7f128449778 136 SUPERFAMILY SSF69635 2 132 1.14E-13 T 29-03-2018 MC49_RS02745 2ad49cd4c2badd14b8fbf7f128449778 136 Gene3D G3DSA:3.30.1460.10 1 133 3.5E-33 T 29-03-2018 MC49_RS02745 2ad49cd4c2badd14b8fbf7f128449778 136 Pfam PF03519 Invasion protein B family 24 94 1.1E-7 T 29-03-2018 IPR003065 Surface presentation of antigens protein SpaK MC49_RS14265 66d429ffca88e5681709559fa3564d7c 148 Pfam PF03692 Putative zinc- or iron-chelating domain 23 92 3.9E-7 T 29-03-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein MC49_RS14265 66d429ffca88e5681709559fa3564d7c 148 PIRSF PIRSF006173 1 145 5.5E-63 T 29-03-2018 IPR008228 Uncharacterised conserved protein UCP006173 MC49_RS14265 66d429ffca88e5681709559fa3564d7c 148 Hamap MF_00676 UPF0260 protein YcgN [ycgN]. 1 145 39.375 T 29-03-2018 IPR008228 Uncharacterised conserved protein UCP006173 MC49_RS17370 957f9f635b8017006bc33b50d1bcea98 134 SUPERFAMILY SSF55298 1 134 2.2E-29 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like MC49_RS17370 957f9f635b8017006bc33b50d1bcea98 134 Gene3D G3DSA:3.30.1330.40 4 134 1.7E-27 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like MC49_RS17370 957f9f635b8017006bc33b50d1bcea98 134 Pfam PF01042 Endoribonuclease L-PSP 18 132 1.3E-20 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family MC49_RS04320 cd10f048b728e4c8cf7c98e9aa77a0fa 836 Pfam PF00577 Outer membrane usher protein 183 752 1.7E-146 T 29-03-2018 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 MC49_RS04320 cd10f048b728e4c8cf7c98e9aa77a0fa 836 Pfam PF13954 PapC N-terminal domain 26 165 4.5E-30 T 29-03-2018 IPR025885 PapC, N-terminal domain GO:0005515 MC49_RS04320 cd10f048b728e4c8cf7c98e9aa77a0fa 836 SUPERFAMILY SSF141729 48 156 1.31E-18 T 29-03-2018 MC49_RS04320 cd10f048b728e4c8cf7c98e9aa77a0fa 836 Pfam PF13953 PapC C-terminal domain 763 821 1.0E-12 T 29-03-2018 IPR025949 PapC-like, C-terminal domain MC49_RS16015 dba9495995a017dddc5dd7592ade9494 284 Pfam PF00950 ABC 3 transport family 15 269 4.2E-92 T 29-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 MC49_RS16015 dba9495995a017dddc5dd7592ade9494 284 SUPERFAMILY SSF81345 8 267 3.14E-45 T 29-03-2018 IPR029022 ABC transporter, BtuC-like MC49_RS16015 dba9495995a017dddc5dd7592ade9494 284 Gene3D G3DSA:1.10.3470.10 7 275 3.8E-29 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like MC49_RS17725 23a2f6d1139c7bc2196a0d40caa492f0 161 Gene3D G3DSA:1.25.40.10 45 159 8.1E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MC49_RS13545 c5364c1ba6d91003380578025f1bd97d 458 Gene3D G3DSA:2.40.50.140 13 105 3.4E-6 T 29-03-2018 MC49_RS13545 c5364c1ba6d91003380578025f1bd97d 458 Gene3D G3DSA:3.90.226.10 139 407 0.0024 T 29-03-2018 MC49_RS13545 c5364c1ba6d91003380578025f1bd97d 458 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 7 443 29.918 T 29-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 MC49_RS13545 c5364c1ba6d91003380578025f1bd97d 458 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 11 354 5.8E-138 T 29-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 MC49_RS13545 c5364c1ba6d91003380578025f1bd97d 458 Pfam PF02601 Exonuclease VII, large subunit 126 440 1.0E-103 T 29-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 MC49_RS13545 c5364c1ba6d91003380578025f1bd97d 458 Pfam PF13742 OB-fold nucleic acid binding domain 10 103 3.2E-31 T 29-03-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 MC49_RS15420 8b30ce8affe645ae5a213f64b672cc28 213 Pfam PF00857 Isochorismatase family 4 206 8.8E-35 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 MC49_RS15420 8b30ce8affe645ae5a213f64b672cc28 213 Gene3D G3DSA:3.40.50.850 1 212 1.5E-62 T 29-03-2018 MC49_RS15420 8b30ce8affe645ae5a213f64b672cc28 213 SUPERFAMILY SSF52499 2 210 3.27E-53 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 MC49_RS12765 6660ae5d87dc77267a744a7cf6832b4f 240 PIRSF PIRSF039085 1 240 2.9E-115 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MC49_RS12765 6660ae5d87dc77267a744a7cf6832b4f 240 SMART SM00382 26 212 6.5E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS12765 6660ae5d87dc77267a744a7cf6832b4f 240 SUPERFAMILY SSF52540 1 235 1.94E-81 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS12765 6660ae5d87dc77267a744a7cf6832b4f 240 Gene3D G3DSA:3.40.50.300 1 239 4.7E-79 T 29-03-2018 MC49_RS12765 6660ae5d87dc77267a744a7cf6832b4f 240 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS12765 6660ae5d87dc77267a744a7cf6832b4f 240 Pfam PF00005 ABC transporter 17 165 6.6E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS11540 79c02f310c6702625f9317b96b09b12e 307 Gene3D G3DSA:3.40.190.10 185 270 1.8E-16 T 29-03-2018 MC49_RS11540 79c02f310c6702625f9317b96b09b12e 307 SUPERFAMILY SSF53850 98 303 8.14E-26 T 29-03-2018 MC49_RS11540 79c02f310c6702625f9317b96b09b12e 307 SUPERFAMILY SSF46785 8 92 1.33E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS11540 79c02f310c6702625f9317b96b09b12e 307 Pfam PF03466 LysR substrate binding domain 97 296 2.8E-24 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS11540 79c02f310c6702625f9317b96b09b12e 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 50 6.6E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS11540 79c02f310c6702625f9317b96b09b12e 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 40 6.6E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS11540 79c02f310c6702625f9317b96b09b12e 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 50 61 6.6E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS11540 79c02f310c6702625f9317b96b09b12e 307 Gene3D G3DSA:1.10.10.10 9 94 7.9E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS11540 79c02f310c6702625f9317b96b09b12e 307 Gene3D G3DSA:3.40.190.10 99 184 1.0E-13 T 29-03-2018 MC49_RS11540 79c02f310c6702625f9317b96b09b12e 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 15 73 5.6E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS03870 ce91ca5bb3970c3e504efa74e48ccbd1 159 Pfam PF05638 Type VI secretion system effector, Hcp 6 143 1.3E-23 T 29-03-2018 IPR008514 Type VI secretion system effector, Hcp MC49_RS03870 ce91ca5bb3970c3e504efa74e48ccbd1 159 Gene3D G3DSA:2.30.110.20 2 158 2.4E-44 T 29-03-2018 IPR008514 Type VI secretion system effector, Hcp MC49_RS03870 ce91ca5bb3970c3e504efa74e48ccbd1 159 SUPERFAMILY SSF141452 2 156 4.32E-35 T 29-03-2018 IPR008514 Type VI secretion system effector, Hcp MC49_RS03870 ce91ca5bb3970c3e504efa74e48ccbd1 159 TIGRFAM TIGR03344 VI_effect_Hcp1: type VI secretion system effector, Hcp1 family 1 153 5.9E-57 T 29-03-2018 IPR008514 Type VI secretion system effector, Hcp MC49_RS16450 9704b6074b8d53e11e2847c52da60f94 257 Pfam PF12697 Alpha/beta hydrolase family 18 246 3.9E-16 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MC49_RS16450 9704b6074b8d53e11e2847c52da60f94 257 TIGRFAM TIGR03695 menH_SHCHC: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase 16 252 6.8E-77 T 29-03-2018 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 MC49_RS16450 9704b6074b8d53e11e2847c52da60f94 257 Gene3D G3DSA:3.40.50.1820 2 254 1.5E-38 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS16450 9704b6074b8d53e11e2847c52da60f94 257 SUPERFAMILY SSF53474 9 252 3.95E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS16450 9704b6074b8d53e11e2847c52da60f94 257 Hamap MF_01660 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase [menH]. 10 253 32.579 T 29-03-2018 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 MC49_RS17185 568dfc924392248471281af5814a7dab 272 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS17185 568dfc924392248471281af5814a7dab 272 SMART SM00382 37 222 3.8E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS17185 568dfc924392248471281af5814a7dab 272 Pfam PF00005 ABC transporter 35 172 2.0E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS17185 568dfc924392248471281af5814a7dab 272 Gene3D G3DSA:3.40.50.300 6 250 2.2E-53 T 29-03-2018 MC49_RS17185 568dfc924392248471281af5814a7dab 272 SUPERFAMILY SSF52540 12 235 4.28E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS01160 68be483586f813c320f0cf6f593234db 94 Gene3D G3DSA:1.10.1220.10 1 89 1.6E-14 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 MC49_RS01160 68be483586f813c320f0cf6f593234db 94 SUPERFAMILY SSF47598 47 88 4.45E-8 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 MC49_RS15020 2dcd71355b3e3039b2a7dd23ef131b5d 193 Hamap MF_00459 Electron transport complex subunit RsxA [rsxA]. 2 191 26.426 T 29-03-2018 IPR011293 Electron transport complex, subunit RnfA/RsxA GO:0022900 MC49_RS15020 2dcd71355b3e3039b2a7dd23ef131b5d 193 TIGRFAM TIGR01943 rnfA: electron transport complex, RnfABCDGE type, A subunit 3 191 1.2E-90 T 29-03-2018 IPR011293 Electron transport complex, subunit RnfA/RsxA GO:0022900 MC49_RS15020 2dcd71355b3e3039b2a7dd23ef131b5d 193 Pfam PF02508 Rnf-Nqr subunit, membrane protein 5 190 8.7E-61 T 29-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 MC49_RS15020 2dcd71355b3e3039b2a7dd23ef131b5d 193 PIRSF PIRSF006102 1 193 1.5E-60 T 29-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 MC49_RS12930 39f7cb5d8a4605c95b2cd7f5b11d359c 69 Gene3D G3DSA:1.10.260.40 4 69 9.0E-11 T 29-03-2018 MC49_RS12930 39f7cb5d8a4605c95b2cd7f5b11d359c 69 SMART SM00530 5 60 6.5E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS12930 39f7cb5d8a4605c95b2cd7f5b11d359c 69 SUPERFAMILY SSF47413 6 60 2.23E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS12930 39f7cb5d8a4605c95b2cd7f5b11d359c 69 Pfam PF01381 Helix-turn-helix 6 59 8.4E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS09455 337945d256c4ff6eeab176b691c05594 943 Gene3D G3DSA:2.60.120.260 2 157 1.5E-8 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS09455 337945d256c4ff6eeab176b691c05594 943 Gene3D G3DSA:2.60.120.260 280 474 3.6E-6 T 29-03-2018 IPR008979 Galactose-binding domain-like MC49_RS03385 d9e2cfddf3120ead4ceee8394590b404 160 Gene3D G3DSA:2.30.30.180 97 157 2.5E-17 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal MC49_RS03385 d9e2cfddf3120ead4ceee8394590b404 160 Pfam PF17384 RimP C-terminal SH3 domain 95 160 3.1E-22 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal MC49_RS03385 d9e2cfddf3120ead4ceee8394590b404 160 SUPERFAMILY SSF75420 9 92 1.83E-24 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal MC49_RS03385 d9e2cfddf3120ead4ceee8394590b404 160 Gene3D G3DSA:3.30.300.70 9 89 7.5E-27 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal MC49_RS03385 d9e2cfddf3120ead4ceee8394590b404 160 Pfam PF02576 RimP N-terminal domain 22 92 1.2E-27 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal MC49_RS03385 d9e2cfddf3120ead4ceee8394590b404 160 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 16 160 24.371 T 29-03-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 MC49_RS03385 d9e2cfddf3120ead4ceee8394590b404 160 SUPERFAMILY SSF74942 93 160 2.48E-17 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal MC49_RS00045 e1ab9b7295c1b646b81424189edc3a24 323 SUPERFAMILY SSF117892 74 204 2.75E-6 T 29-03-2018 IPR001107 Band 7 domain MC49_RS00045 e1ab9b7295c1b646b81424189edc3a24 323 Pfam PF01145 SPFH domain / Band 7 family 50 217 2.7E-15 T 29-03-2018 IPR001107 Band 7 domain MC49_RS00045 e1ab9b7295c1b646b81424189edc3a24 323 SMART SM00244 34 202 0.0017 T 29-03-2018 IPR001107 Band 7 domain MC49_RS16845 2c6350691c9a31c636d813c3036e1bd7 291 Pfam PF01925 Sulfite exporter TauE/SafE 28 286 2.5E-36 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MC49_RS12835 eead5c06f9cbb5fe48ebf7c1b97b9131 948 Gene3D G3DSA:3.30.565.10 530 693 1.7E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS12835 eead5c06f9cbb5fe48ebf7c1b97b9131 948 SUPERFAMILY SSF55874 524 693 2.62E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS12835 eead5c06f9cbb5fe48ebf7c1b97b9131 948 PRINTS PR00344 Bacterial sensor protein C-terminal signature 636 646 1.3E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS12835 eead5c06f9cbb5fe48ebf7c1b97b9131 948 PRINTS PR00344 Bacterial sensor protein C-terminal signature 653 671 1.3E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS12835 eead5c06f9cbb5fe48ebf7c1b97b9131 948 PRINTS PR00344 Bacterial sensor protein C-terminal signature 618 632 1.3E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS12835 eead5c06f9cbb5fe48ebf7c1b97b9131 948 PRINTS PR00344 Bacterial sensor protein C-terminal signature 677 690 1.3E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS12835 eead5c06f9cbb5fe48ebf7c1b97b9131 948 SMART SM00388 470 535 1.3E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS12835 eead5c06f9cbb5fe48ebf7c1b97b9131 948 Gene3D G3DSA:1.10.287.130 474 529 2.1E-20 T 29-03-2018 MC49_RS12835 eead5c06f9cbb5fe48ebf7c1b97b9131 948 Gene3D G3DSA:3.40.50.2300 812 944 1.2E-41 T 29-03-2018 MC49_RS12835 eead5c06f9cbb5fe48ebf7c1b97b9131 948 Gene3D G3DSA:3.30.450.20 333 473 4.0E-8 T 29-03-2018 MC49_RS12835 eead5c06f9cbb5fe48ebf7c1b97b9131 948 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 582 690 3.4E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS12835 eead5c06f9cbb5fe48ebf7c1b97b9131 948 Pfam PF00072 Response regulator receiver domain 826 935 5.3E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS12835 eead5c06f9cbb5fe48ebf7c1b97b9131 948 SMART SM00448 824 935 1.2E-36 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS12835 eead5c06f9cbb5fe48ebf7c1b97b9131 948 Pfam PF00512 His Kinase A (phospho-acceptor) domain 470 534 3.7E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS12835 eead5c06f9cbb5fe48ebf7c1b97b9131 948 SUPERFAMILY SSF47384 454 536 4.9E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS12835 eead5c06f9cbb5fe48ebf7c1b97b9131 948 SMART SM00387 582 693 3.2E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS12835 eead5c06f9cbb5fe48ebf7c1b97b9131 948 SUPERFAMILY SSF52172 824 940 6.12E-39 T 29-03-2018 IPR011006 CheY-like superfamily MC49_RS12835 eead5c06f9cbb5fe48ebf7c1b97b9131 948 SUPERFAMILY SSF52172 710 808 6.42E-5 T 29-03-2018 IPR011006 CheY-like superfamily MC49_RS18505 7e7341a565dee3f0f7817c1d0db75130 207 Hamap MF_01901 Arginine exporter protein ArgO [argO]. 1 205 38.284 T 29-03-2018 IPR023445 Arginine exporter protein ArgO, enterobacteria GO:0015181|GO:0015809 MC49_RS18505 7e7341a565dee3f0f7817c1d0db75130 207 Pfam PF01810 LysE type translocator 14 202 5.6E-49 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MC49_RS15115 08a69aaf961d1081ac398fc5ff6641cc 83 Pfam PF10692 Protein of unknown function (DUF2498) 5 81 1.3E-43 T 29-03-2018 IPR019633 Protein of unknown function DUF2498 MC49_RS11710 edd7e8e640780b55b610127201222526 159 Pfam PF05638 Type VI secretion system effector, Hcp 6 143 1.4E-21 T 29-03-2018 IPR008514 Type VI secretion system effector, Hcp MC49_RS11710 edd7e8e640780b55b610127201222526 159 Gene3D G3DSA:2.30.110.20 2 159 7.2E-41 T 29-03-2018 IPR008514 Type VI secretion system effector, Hcp MC49_RS11710 edd7e8e640780b55b610127201222526 159 TIGRFAM TIGR03344 VI_effect_Hcp1: type VI secretion system effector, Hcp1 family 4 156 1.4E-50 T 29-03-2018 IPR008514 Type VI secretion system effector, Hcp MC49_RS11710 edd7e8e640780b55b610127201222526 159 SUPERFAMILY SSF141452 6 152 1.57E-32 T 29-03-2018 IPR008514 Type VI secretion system effector, Hcp MC49_RS01415 adb4d4cb6fefc703b4ca36668d57302c 190 Pfam PF04972 BON domain 46 112 4.2E-11 T 29-03-2018 IPR007055 BON domain MC49_RS01415 adb4d4cb6fefc703b4ca36668d57302c 190 Pfam PF04972 BON domain 124 187 8.8E-15 T 29-03-2018 IPR007055 BON domain MC49_RS01415 adb4d4cb6fefc703b4ca36668d57302c 190 SMART SM00749 51 113 2.8 T 29-03-2018 IPR014004 Transport-associated and nodulation domain, bacteria MC49_RS01415 adb4d4cb6fefc703b4ca36668d57302c 190 SMART SM00749 128 185 0.73 T 29-03-2018 IPR014004 Transport-associated and nodulation domain, bacteria MC49_RS07855 f1c7b9c2eb9dae45fd9584a7195b005a 298 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 1 286 2.4E-100 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 MC49_RS07855 f1c7b9c2eb9dae45fd9584a7195b005a 298 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 13 278 1.3E-80 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 MC49_RS07855 f1c7b9c2eb9dae45fd9584a7195b005a 298 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 10 283 20.508 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 MC49_RS07855 f1c7b9c2eb9dae45fd9584a7195b005a 298 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 142 154 - T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 MC49_RS09695 6d823ea8375fd0985eceaec707bf4a4b 258 Pfam PF13230 Glutamine amidotransferases class-II 1 253 2.8E-108 T 29-03-2018 IPR026869 Putative glutamine amidotransferase type 2 MC49_RS09695 6d823ea8375fd0985eceaec707bf4a4b 258 Gene3D G3DSA:3.60.20.10 1 256 1.9E-45 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MC49_RS09695 6d823ea8375fd0985eceaec707bf4a4b 258 SUPERFAMILY SSF56235 2 252 6.95E-49 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MC49_RS17870 42c241f5c40761974c10f287202980fc 206 Gene3D G3DSA:3.40.109.10 2 205 3.4E-40 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MC49_RS17870 42c241f5c40761974c10f287202980fc 206 SUPERFAMILY SSF55469 1 202 2.09E-47 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MC49_RS17870 42c241f5c40761974c10f287202980fc 206 Pfam PF00881 Nitroreductase family 7 178 3.5E-30 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MC49_RS09515 877c8a435d0a8aa433efc4dce742d796 295 SUPERFAMILY SSF46689 13 87 2.69E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS09515 877c8a435d0a8aa433efc4dce742d796 295 Gene3D G3DSA:1.10.10.10 9 88 3.5E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS09515 877c8a435d0a8aa433efc4dce742d796 295 SUPERFAMILY SSF53697 108 285 2.88E-42 T 29-03-2018 MC49_RS09515 877c8a435d0a8aa433efc4dce742d796 295 Pfam PF01418 Helix-turn-helix domain, rpiR family 14 87 1.4E-22 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 MC49_RS09515 877c8a435d0a8aa433efc4dce742d796 295 Pfam PF01380 SIS domain 140 268 5.5E-21 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MC49_RS09515 877c8a435d0a8aa433efc4dce742d796 295 Gene3D G3DSA:3.40.50.10490 96 294 1.0E-37 T 29-03-2018 MC49_RS09805 5130fff11429f38124ed349dab4e4553 173 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 16 162 1.0E-52 T 29-03-2018 IPR008136 CinA, C-terminal MC49_RS09805 5130fff11429f38124ed349dab4e4553 173 SUPERFAMILY SSF142433 9 165 3.92E-55 T 29-03-2018 IPR008136 CinA, C-terminal MC49_RS09805 5130fff11429f38124ed349dab4e4553 173 Gene3D G3DSA:3.90.950.20 3 170 1.2E-55 T 29-03-2018 MC49_RS09805 5130fff11429f38124ed349dab4e4553 173 Pfam PF02464 Competence-damaged protein 12 163 4.3E-56 T 29-03-2018 IPR008136 CinA, C-terminal MC49_RS18455 689e3aa8edee52d1b8cd7230b09fc452 400 Gene3D G3DSA:3.50.50.60 2 351 1.1E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS18455 689e3aa8edee52d1b8cd7230b09fc452 400 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 3 387 3.9E-131 T 29-03-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 MC49_RS18455 689e3aa8edee52d1b8cd7230b09fc452 400 SUPERFAMILY SSF51905 2 174 4.39E-51 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS18455 689e3aa8edee52d1b8cd7230b09fc452 400 SUPERFAMILY SSF51905 264 381 4.39E-51 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS18455 689e3aa8edee52d1b8cd7230b09fc452 400 Pfam PF01494 FAD binding domain 2 342 9.8E-22 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 MC49_RS18455 689e3aa8edee52d1b8cd7230b09fc452 400 TIGRFAM TIGR01984 UbiH: 2-polyprenyl-6-methoxyphenol 4-hydroxylase 3 387 1.1E-145 T 29-03-2018 IPR011295 2-polyprenyl-6-methoxyphenol 4-hydroxylase GO:0006744|GO:0008681 MC49_RS18455 689e3aa8edee52d1b8cd7230b09fc452 400 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 291 304 - T 29-03-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 MC49_RS18455 689e3aa8edee52d1b8cd7230b09fc452 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 308 1.7E-13 T 29-03-2018 MC49_RS18455 689e3aa8edee52d1b8cd7230b09fc452 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 153 168 1.7E-13 T 29-03-2018 MC49_RS18455 689e3aa8edee52d1b8cd7230b09fc452 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 1.7E-13 T 29-03-2018 MC49_RS18455 689e3aa8edee52d1b8cd7230b09fc452 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 277 292 1.7E-13 T 29-03-2018 MC49_RS08785 565db23c15bc50b2a243f4d72450ceda 395 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 186 372 1.0E-40 T 29-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 MC49_RS08785 565db23c15bc50b2a243f4d72450ceda 395 SUPERFAMILY SSF53671 17 373 5.24E-57 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MC49_RS08785 565db23c15bc50b2a243f4d72450ceda 395 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 21 177 1.5E-23 T 29-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 MC49_RS08785 565db23c15bc50b2a243f4d72450ceda 395 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 66 85 2.8E-8 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MC49_RS08785 565db23c15bc50b2a243f4d72450ceda 395 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 322 331 2.8E-8 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MC49_RS08785 565db23c15bc50b2a243f4d72450ceda 395 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 340 363 2.8E-8 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MC49_RS08785 565db23c15bc50b2a243f4d72450ceda 395 Gene3D G3DSA:3.40.50.1370 177 376 4.1E-37 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MC49_RS08785 565db23c15bc50b2a243f4d72450ceda 395 TIGRFAM TIGR03316 ygeW: knotted carbamoyltransferase YgeW 6 393 7.9E-201 T 29-03-2018 IPR017702 Putative carbamoyltransferase YgeW MC49_RS08785 565db23c15bc50b2a243f4d72450ceda 395 Gene3D G3DSA:3.40.50.1370 7 176 3.6E-32 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MC49_RS08785 565db23c15bc50b2a243f4d72450ceda 395 PRINTS PR00101 Aspartate carbamoyltransferase signature 94 103 3.9E-7 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MC49_RS08785 565db23c15bc50b2a243f4d72450ceda 395 PRINTS PR00101 Aspartate carbamoyltransferase signature 163 180 3.9E-7 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MC49_RS08785 565db23c15bc50b2a243f4d72450ceda 395 PRINTS PR00101 Aspartate carbamoyltransferase signature 56 78 3.9E-7 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MC49_RS18665 f84f96d23c4d4b544a2fd79371bd068a 360 ProSitePatterns PS01348 MraY family signature 2. 189 200 - T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MC49_RS18665 f84f96d23c4d4b544a2fd79371bd068a 360 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 25 358 25.789 T 29-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MC49_RS18665 f84f96d23c4d4b544a2fd79371bd068a 360 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 38 360 4.5E-157 T 29-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MC49_RS18665 f84f96d23c4d4b544a2fd79371bd068a 360 Pfam PF00953 Glycosyl transferase family 4 99 284 1.0E-36 T 29-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 MC49_RS01880 49f70c728dfe57c918013bb3792f219c 210 Pfam PF07947 YhhN family 26 206 3.3E-22 T 29-03-2018 IPR012506 YhhN-like GO:0016021 MC49_RS17080 2a883264194ddc0350dc212dae20f5f2 279 ProSitePatterns PS00770 Aminotransferases class-IV signature. 177 206 - T 29-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 MC49_RS17080 2a883264194ddc0350dc212dae20f5f2 279 Pfam PF01063 Amino-transferase class IV 29 251 3.8E-45 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 MC49_RS17080 2a883264194ddc0350dc212dae20f5f2 279 SUPERFAMILY SSF56752 7 252 6.67E-63 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 MC49_RS17080 2a883264194ddc0350dc212dae20f5f2 279 Gene3D G3DSA:3.20.10.10 118 268 3.9E-31 T 29-03-2018 MC49_RS17080 2a883264194ddc0350dc212dae20f5f2 279 TIGRFAM TIGR03461 pabC_Proteo: aminodeoxychorismate lyase 8 270 5.8E-94 T 29-03-2018 IPR017824 Aminodeoxychorismate lyase, class IV GO:0008696|GO:0030170|GO:0046656 KEGG: 00790+4.1.3.38|MetaCyc: PWY-6543 MC49_RS17080 2a883264194ddc0350dc212dae20f5f2 279 Gene3D G3DSA:3.30.470.10 1 114 2.9E-22 T 29-03-2018 MC49_RS13510 59ea06d6826a199219f7debbb16ea159 190 Gene3D G3DSA:3.40.50.850 1 190 1.7E-35 T 29-03-2018 MC49_RS13510 59ea06d6826a199219f7debbb16ea159 190 Pfam PF00857 Isochorismatase family 4 185 1.9E-35 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 MC49_RS13510 59ea06d6826a199219f7debbb16ea159 190 SUPERFAMILY SSF52499 2 188 8.5E-40 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 MC49_RS04810 8503f2589a9e846203747761cfa9666e 402 SUPERFAMILY SSF56349 98 380 5.3E-63 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MC49_RS04810 8503f2589a9e846203747761cfa9666e 402 Pfam PF00589 Phage integrase family 206 370 3.5E-24 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MC49_RS04810 8503f2589a9e846203747761cfa9666e 402 Gene3D G3DSA:1.10.443.10 204 386 4.5E-24 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MC49_RS04810 8503f2589a9e846203747761cfa9666e 402 Pfam PF13356 Arm DNA-binding domain 3 88 9.7E-18 T 29-03-2018 IPR025166 Integrase, DNA-binding domain MC49_RS04810 8503f2589a9e846203747761cfa9666e 402 Gene3D G3DSA:1.10.150.130 88 203 1.9E-19 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal MC49_RS05755 c9a687f18c2d73b588e93d5474f09513 396 SUPERFAMILY SSF51735 34 280 3.61E-27 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS05755 c9a687f18c2d73b588e93d5474f09513 396 Gene3D G3DSA:3.40.50.720 30 381 5.6E-36 T 29-03-2018 MC49_RS05755 c9a687f18c2d73b588e93d5474f09513 396 Pfam PF02719 Polysaccharide biosynthesis protein 36 284 8.8E-45 T 29-03-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain MC49_RS09320 dd98dfbc89109ed9bfddcf40f9328f83 191 Pfam PF02342 TerD domain 1 187 2.2E-84 T 29-03-2018 IPR003325 TerD domain GO:0006950 MC49_RS09320 dd98dfbc89109ed9bfddcf40f9328f83 191 Gene3D G3DSA:2.60.60.30 20 186 6.6E-63 T 29-03-2018 MC49_RS10785 326c7068dee36b600b22dba0fb7a308e 150 Pfam PF03788 LrgA family 25 115 3.1E-28 T 29-03-2018 IPR005538 LrgA/CidA family GO:0016021 MC49_RS10785 326c7068dee36b600b22dba0fb7a308e 150 Hamap MF_01144 UPF0299 membrane protein YohJ [yohJ]. 6 125 21.227 T 29-03-2018 IPR022957 Uncharacterised protein family UPF0299 MC49_RS05615 1d84aeb7462b1bcb06c5975cb86e8b2d 325 TIGRFAM TIGR02193 heptsyl_trn_I: lipopolysaccharide heptosyltransferase I 3 321 1.2E-125 T 29-03-2018 IPR011908 Lipopolysaccharide heptosyltransferase I GO:0008920|GO:0009244 MC49_RS05615 1d84aeb7462b1bcb06c5975cb86e8b2d 325 Gene3D G3DSA:3.40.50.2000 2 164 1.0E-38 T 29-03-2018 MC49_RS05615 1d84aeb7462b1bcb06c5975cb86e8b2d 325 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 76 310 1.8E-68 T 29-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 MC49_RS05615 1d84aeb7462b1bcb06c5975cb86e8b2d 325 SUPERFAMILY SSF53756 2 323 2.72E-71 T 29-03-2018 MC49_RS05615 1d84aeb7462b1bcb06c5975cb86e8b2d 325 Gene3D G3DSA:3.40.50.2000 165 325 1.6E-33 T 29-03-2018 MC49_RS04865 8da8e7fac6b97f3fd2526548d2c7fb89 352 Pfam PF11726 Inovirus Gp2 177 325 7.2E-17 T 29-03-2018 MC49_RS09220 ab6ff19eebbd474544c23ec56a6f1fe9 156 Pfam PF00075 RNase H 4 141 3.1E-51 T 29-03-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 MC49_RS09220 ab6ff19eebbd474544c23ec56a6f1fe9 156 Hamap MF_00042 Ribonuclease H [rnhA]. 2 150 36.771 T 29-03-2018 IPR022892 Ribonuclease HI GO:0004523 MC49_RS09220 ab6ff19eebbd474544c23ec56a6f1fe9 156 SUPERFAMILY SSF53098 3 142 1.52E-57 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MC49_RS09220 ab6ff19eebbd474544c23ec56a6f1fe9 156 Gene3D G3DSA:3.30.420.10 1 154 1.9E-53 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MC49_RS17720 d30d033d7f40eb03e2d361e905ba38c7 197 Pfam PF07105 Protein of unknown function (DUF1367) 1 196 6.1E-83 T 29-03-2018 IPR009797 Protein of unknown function DUF1367 MC49_RS05035 ad4d41e9876a01a099664a7f07e2ecb2 280 SUPERFAMILY SSF47616 181 259 7.1E-35 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like MC49_RS05035 ad4d41e9876a01a099664a7f07e2ecb2 280 SUPERFAMILY SSF47616 117 152 7.1E-35 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like MC49_RS05035 ad4d41e9876a01a099664a7f07e2ecb2 280 Gene3D G3DSA:3.40.30.10 45 143 8.6E-26 T 29-03-2018 MC49_RS05035 ad4d41e9876a01a099664a7f07e2ecb2 280 Pfam PF00043 Glutathione S-transferase, C-terminal domain 182 250 8.5E-9 T 29-03-2018 IPR004046 Glutathione S-transferase, C-terminal MC49_RS05035 ad4d41e9876a01a099664a7f07e2ecb2 280 SUPERFAMILY SSF52833 38 130 4.49E-18 T 29-03-2018 IPR012336 Thioredoxin-like fold MC49_RS05035 ad4d41e9876a01a099664a7f07e2ecb2 280 Gene3D G3DSA:1.20.1050.10 144 187 4.2E-10 T 29-03-2018 MC49_RS05035 ad4d41e9876a01a099664a7f07e2ecb2 280 Gene3D G3DSA:1.20.1050.10 188 254 5.4E-15 T 29-03-2018 MC49_RS05035 ad4d41e9876a01a099664a7f07e2ecb2 280 Pfam PF02798 Glutathione S-transferase, N-terminal domain 55 127 2.4E-7 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MC49_RS07005 4c1753f7bfdd7d69e4d24a71f6e502af 944 Gene3D G3DSA:3.40.50.300 412 609 4.1E-21 T 29-03-2018 MC49_RS07005 4c1753f7bfdd7d69e4d24a71f6e502af 944 Gene3D G3DSA:1.10.8.280 285 405 7.6E-37 T 29-03-2018 MC49_RS07005 4c1753f7bfdd7d69e4d24a71f6e502af 944 Gene3D G3DSA:3.40.50.300 34 73 0.063 T 29-03-2018 MC49_RS07005 4c1753f7bfdd7d69e4d24a71f6e502af 944 Hamap MF_00205 UvrABC system protein A [uvrA]. 1 940 22.928 T 29-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 MC49_RS07005 4c1753f7bfdd7d69e4d24a71f6e502af 944 SUPERFAMILY SSF52540 613 911 4.94E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS07005 4c1753f7bfdd7d69e4d24a71f6e502af 944 ProSitePatterns PS00211 ABC transporters family signature. 830 844 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS07005 4c1753f7bfdd7d69e4d24a71f6e502af 944 Gene3D G3DSA:3.40.50.300 610 940 7.8E-54 T 29-03-2018 MC49_RS07005 4c1753f7bfdd7d69e4d24a71f6e502af 944 SUPERFAMILY SSF52540 1 204 2.28E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS07005 4c1753f7bfdd7d69e4d24a71f6e502af 944 SUPERFAMILY SSF52540 430 569 2.28E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS07005 4c1753f7bfdd7d69e4d24a71f6e502af 944 Gene3D G3DSA:3.30.190.20 127 248 6.0E-42 T 29-03-2018 MC49_RS07005 4c1753f7bfdd7d69e4d24a71f6e502af 944 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 4 925 0.0 T 29-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 MC49_RS07005 4c1753f7bfdd7d69e4d24a71f6e502af 944 ProSitePatterns PS00211 ABC transporters family signature. 487 501 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS07005 4c1753f7bfdd7d69e4d24a71f6e502af 944 Gene3D G3DSA:3.40.50.300 5 33 0.0013 T 29-03-2018 MC49_RS07005 4c1753f7bfdd7d69e4d24a71f6e502af 944 Pfam PF00005 ABC transporter 623 860 4.8E-10 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS02660 1e1abdae5afb91b6bbf5cd486fd1726a 285 Gene3D G3DSA:3.20.80.10 129 276 5.5E-14 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain MC49_RS02660 1e1abdae5afb91b6bbf5cd486fd1726a 285 Pfam PF13411 MerR HTH family regulatory protein 5 73 6.1E-16 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MC49_RS02660 1e1abdae5afb91b6bbf5cd486fd1726a 285 Gene3D G3DSA:1.10.1660.10 1 62 7.5E-20 T 29-03-2018 MC49_RS02660 1e1abdae5afb91b6bbf5cd486fd1726a 285 SUPERFAMILY SSF55136 128 274 7.67E-17 T 29-03-2018 MC49_RS02660 1e1abdae5afb91b6bbf5cd486fd1726a 285 SUPERFAMILY SSF46955 3 108 2.78E-28 T 29-03-2018 IPR009061 Putative DNA-binding domain MC49_RS02660 1e1abdae5afb91b6bbf5cd486fd1726a 285 Gene3D G3DSA:1.10.1660.10 63 128 4.2E-10 T 29-03-2018 MC49_RS02660 1e1abdae5afb91b6bbf5cd486fd1726a 285 SMART SM00422 5 75 2.3E-17 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MC49_RS11445 5dc1c756accb09482b8d2b552077cee1 332 Gene3D G3DSA:2.60.40.1090 184 331 1.6E-14 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS11445 5dc1c756accb09482b8d2b552077cee1 332 SUPERFAMILY SSF49401 195 331 1.74E-12 T 29-03-2018 IPR008966 Adhesion domain MC49_RS11445 5dc1c756accb09482b8d2b552077cee1 332 Pfam PF00419 Fimbrial protein 188 331 1.7E-19 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS16655 14460a1132a850662bb6dac04e6a2f1c 309 SUPERFAMILY SSF103481 38 140 2.22E-9 T 29-03-2018 MC49_RS16655 14460a1132a850662bb6dac04e6a2f1c 309 SUPERFAMILY SSF103481 187 284 3.27E-13 T 29-03-2018 MC49_RS16655 14460a1132a850662bb6dac04e6a2f1c 309 Pfam PF00892 EamA-like transporter family 152 281 2.1E-19 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MC49_RS16655 14460a1132a850662bb6dac04e6a2f1c 309 Pfam PF00892 EamA-like transporter family 4 135 2.1E-18 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MC49_RS07310 2d14e314be9448237757ba5da4306f79 264 Pfam PF01026 TatD related DNase 4 259 2.9E-66 T 29-03-2018 IPR001130 TatD family GO:0016788 MC49_RS07310 2d14e314be9448237757ba5da4306f79 264 Gene3D G3DSA:3.20.20.140 1 264 1.8E-79 T 29-03-2018 MC49_RS07310 2d14e314be9448237757ba5da4306f79 264 PIRSF PIRSF005902 1 263 1.3E-67 T 29-03-2018 IPR001130 TatD family GO:0016788 MC49_RS07310 2d14e314be9448237757ba5da4306f79 264 SUPERFAMILY SSF51556 3 260 4.28E-77 T 29-03-2018 IPR032466 Metal-dependent hydrolase MC49_RS07310 2d14e314be9448237757ba5da4306f79 264 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 131 141 - T 29-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 MC49_RS07310 2d14e314be9448237757ba5da4306f79 264 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 195 211 - T 29-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 MC49_RS07310 2d14e314be9448237757ba5da4306f79 264 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 3 11 - T 29-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 MC49_RS05460 b9014daec82a3472222be98cc42ffdf1 142 SUPERFAMILY SSF50331 1 70 4.37E-19 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal MC49_RS05460 b9014daec82a3472222be98cc42ffdf1 142 Gene3D G3DSA:2.40.50.100 72 141 4.1E-20 T 29-03-2018 MC49_RS05460 b9014daec82a3472222be98cc42ffdf1 142 Gene3D G3DSA:2.40.50.100 1 68 2.5E-18 T 29-03-2018 MC49_RS05460 b9014daec82a3472222be98cc42ffdf1 142 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 73 140 1.0E-21 T 29-03-2018 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 MC49_RS05460 b9014daec82a3472222be98cc42ffdf1 142 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 1 68 1.1E-23 T 29-03-2018 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 MC49_RS05460 b9014daec82a3472222be98cc42ffdf1 142 SUPERFAMILY SSF50331 73 140 1.53E-19 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal MC49_RS05460 b9014daec82a3472222be98cc42ffdf1 142 Pfam PF03459 TOBE domain 76 138 2.4E-16 T 29-03-2018 IPR005116 Transport-associated OB, type 1 MC49_RS05460 b9014daec82a3472222be98cc42ffdf1 142 Pfam PF03459 TOBE domain 4 64 2.0E-14 T 29-03-2018 IPR005116 Transport-associated OB, type 1 MC49_RS03315 dbc3ef6c865e247272db0db4c62a8b12 152 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 6 147 3.4E-26 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like MC49_RS03315 dbc3ef6c865e247272db0db4c62a8b12 152 SUPERFAMILY SSF55298 1 150 9.27E-41 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like MC49_RS03315 dbc3ef6c865e247272db0db4c62a8b12 152 Gene3D G3DSA:3.30.1330.40 1 152 1.6E-18 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like MC49_RS17595 d46c9f50526763a3974337882464cf98 712 Gene3D G3DSA:1.20.5.1230 14 600 1.8E-10 T 29-03-2018 MC49_RS03965 771eea5cff2bbe6aecedb5d96885690a 162 SUPERFAMILY SSF51161 2 157 1.66E-41 T 29-03-2018 IPR011004 Trimeric LpxA-like MC49_RS03965 771eea5cff2bbe6aecedb5d96885690a 162 Gene3D G3DSA:2.160.10.10 1 162 5.0E-38 T 29-03-2018 MC49_RS03965 771eea5cff2bbe6aecedb5d96885690a 162 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 78 111 2.2E-8 T 29-03-2018 IPR001451 Hexapeptide repeat MC49_RS01625 9fd4d4232ea549be23031442bb818676 446 Gene3D G3DSA:3.30.2290.10 6 232 1.5E-58 T 29-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain MC49_RS01625 9fd4d4232ea549be23031442bb818676 446 Pfam PF01523 Putative modulator of DNA gyrase 32 323 9.4E-64 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 MC49_RS01625 9fd4d4232ea549be23031442bb818676 446 SUPERFAMILY SSF111283 12 445 4.58E-132 T 29-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 MC49_RS00630 dabb4897f8fdfa0a1475b8aaf3af4ea2 54 Pfam PF10689 Protein of unknown function (DUF2496) 2 44 4.5E-24 T 29-03-2018 IPR019630 Protein of unknown function DUF2496, YbaM-related MC49_RS13645 cfa6498636f4ad75b0b3633f321d5392 188 Gene3D G3DSA:3.90.79.10 8 187 4.8E-45 T 29-03-2018 MC49_RS13645 cfa6498636f4ad75b0b3633f321d5392 188 Pfam PF00293 NUDIX domain 27 108 9.8E-17 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MC49_RS13645 cfa6498636f4ad75b0b3633f321d5392 188 SUPERFAMILY SSF55811 26 182 6.09E-37 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MC49_RS10275 1e87b58335c11033419e8269df21b6bb 269 Gene3D G3DSA:3.40.50.1360 1 266 6.6E-88 T 29-03-2018 MC49_RS10275 1e87b58335c11033419e8269df21b6bb 269 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 10 230 5.8E-21 T 29-03-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 MC49_RS10275 1e87b58335c11033419e8269df21b6bb 269 SUPERFAMILY SSF100950 1 260 5.76E-104 T 29-03-2018 MC49_RS10275 1e87b58335c11033419e8269df21b6bb 269 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 247 40.935 T 29-03-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 MC49_RS10275 1e87b58335c11033419e8269df21b6bb 269 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 125 143 - T 29-03-2018 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 MC49_RS10275 1e87b58335c11033419e8269df21b6bb 269 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 1 259 2.2E-134 T 29-03-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 MC49_RS06790 596bae6c207b78f34ec199bf994e4b92 338 Pfam PF06147 Protein of unknown function (DUF968) 141 335 2.9E-62 T 29-03-2018 IPR010373 Protein of unknown function DUF968 MC49_RS06790 596bae6c207b78f34ec199bf994e4b92 338 SMART SM00507 255 304 0.0038 T 29-03-2018 IPR003615 HNH nuclease MC49_RS06790 596bae6c207b78f34ec199bf994e4b92 338 Gene3D G3DSA:3.30.50.20 264 332 1.1E-17 T 29-03-2018 MC49_RS12500 c8e2ce23f4e0c2c181e5a8169d18eb43 146 Pfam PF05130 FlgN protein 1 135 7.5E-21 T 29-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 MC49_RS12500 c8e2ce23f4e0c2c181e5a8169d18eb43 146 Gene3D G3DSA:1.20.58.300 1 120 2.3E-19 T 29-03-2018 MC49_RS12500 c8e2ce23f4e0c2c181e5a8169d18eb43 146 SUPERFAMILY SSF140566 1 119 4.18E-14 T 29-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 MC49_RS09640 2898a5047723fffaa1407f3df5755d05 243 Pfam PF04452 RNA methyltransferase 19 236 6.9E-75 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MC49_RS09640 2898a5047723fffaa1407f3df5755d05 243 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 2 242 5.9E-86 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MC49_RS09640 2898a5047723fffaa1407f3df5755d05 243 SUPERFAMILY SSF75217 75 242 1.15E-50 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases MC49_RS09640 2898a5047723fffaa1407f3df5755d05 243 SUPERFAMILY SSF88697 2 71 3.73E-17 T 29-03-2018 IPR015947 PUA-like domain MC49_RS09640 2898a5047723fffaa1407f3df5755d05 243 Gene3D G3DSA:3.40.1280.10 74 243 2.3E-56 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MC49_RS09640 2898a5047723fffaa1407f3df5755d05 243 PIRSF PIRSF015601 2 242 7.2E-54 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 MC49_RS09640 2898a5047723fffaa1407f3df5755d05 243 Gene3D G3DSA:2.40.240.20 1 73 5.5E-20 T 29-03-2018 MC49_RS05605 f3cd694acc6f5fd6972b053e8da989d6 373 Pfam PF13439 Glycosyltransferase Family 4 15 186 1.6E-14 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 MC49_RS05605 f3cd694acc6f5fd6972b053e8da989d6 373 Gene3D G3DSA:3.40.50.2000 195 352 8.5E-26 T 29-03-2018 MC49_RS05605 f3cd694acc6f5fd6972b053e8da989d6 373 SUPERFAMILY SSF53756 5 366 1.57E-50 T 29-03-2018 MC49_RS05605 f3cd694acc6f5fd6972b053e8da989d6 373 Pfam PF00534 Glycosyl transferases group 1 190 355 4.2E-24 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 MC49_RS05605 f3cd694acc6f5fd6972b053e8da989d6 373 Gene3D G3DSA:3.40.50.2000 1 194 2.8E-8 T 29-03-2018 MC49_RS14055 ab804b9fde92481ab2b15bd469bf108e 174 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 113 147 - T 29-03-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 MC49_RS14055 ab804b9fde92481ab2b15bd469bf108e 174 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 4 150 9.7E-66 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MC49_RS14055 ab804b9fde92481ab2b15bd469bf108e 174 SUPERFAMILY SSF53098 3 157 4.93E-56 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MC49_RS14055 ab804b9fde92481ab2b15bd469bf108e 174 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 4 157 2.1E-80 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MC49_RS14055 ab804b9fde92481ab2b15bd469bf108e 174 Gene3D G3DSA:3.30.420.10 2 159 1.2E-52 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MC49_RS14055 ab804b9fde92481ab2b15bd469bf108e 174 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 2 153 48.315 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MC49_RS14055 ab804b9fde92481ab2b15bd469bf108e 174 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 138 150 3.6E-44 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MC49_RS14055 ab804b9fde92481ab2b15bd469bf108e 174 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 5 18 3.6E-44 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MC49_RS14055 ab804b9fde92481ab2b15bd469bf108e 174 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 61 77 3.6E-44 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MC49_RS14055 ab804b9fde92481ab2b15bd469bf108e 174 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 83 99 3.6E-44 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MC49_RS14055 ab804b9fde92481ab2b15bd469bf108e 174 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 107 126 3.6E-44 T 29-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MC49_RS13670 3ea8390cdfa6d3d415f1646b62064c70 168 Pfam PF00210 Ferritin-like domain 8 143 1.4E-40 T 29-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 MC49_RS13670 3ea8390cdfa6d3d415f1646b62064c70 168 SUPERFAMILY SSF47240 1 159 5.16E-57 T 29-03-2018 IPR009078 Ferritin-like superfamily MC49_RS13670 3ea8390cdfa6d3d415f1646b62064c70 168 Gene3D G3DSA:1.20.1260.10 1 162 4.6E-42 T 29-03-2018 IPR012347 Ferritin-related MC49_RS12655 0d58c7eaaa33a9c36ad4bca27c920b02 197 Pfam PF01292 Prokaryotic cytochrome b561 16 183 2.1E-8 T 29-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 MC49_RS12655 0d58c7eaaa33a9c36ad4bca27c920b02 197 Gene3D G3DSA:1.20.950.20 11 188 2.5E-8 T 29-03-2018 MC49_RS07095 2b532303dac7e5b462314720e52ee933 474 Gene3D G3DSA:1.20.5.340 147 298 2.9E-24 T 29-03-2018 MC49_RS07095 2b532303dac7e5b462314720e52ee933 474 Pfam PF02646 RmuC family 137 432 1.5E-103 T 29-03-2018 IPR003798 DNA recombination RmuC MC49_RS06170 ff884af815100862954faff37ad4450e 330 TIGRFAM TIGR00766 TIGR00766: inner membrane protein YhjD 52 323 1.6E-101 T 29-03-2018 IPR005274 Inner membrane protein YhjD MC49_RS06170 ff884af815100862954faff37ad4450e 330 Pfam PF03631 Virulence factor BrkB 67 322 1.0E-42 T 29-03-2018 IPR017039 Virulence factor BrkB MC49_RS06170 ff884af815100862954faff37ad4450e 330 PIRSF PIRSF035875 49 326 5.5E-25 T 29-03-2018 IPR017039 Virulence factor BrkB MC49_RS15700 fdfe9fab63cbdc7a4dc384d6b2ae84a9 113 PIRSF PIRSF005894 1 108 3.4E-52 T 29-03-2018 IPR014434 Monothiol glutaredoxin GO:0015036 Reactome: R-HSA-1362409 MC49_RS15700 fdfe9fab63cbdc7a4dc384d6b2ae84a9 113 SUPERFAMILY SSF52833 2 104 5.42E-35 T 29-03-2018 IPR012336 Thioredoxin-like fold MC49_RS15700 fdfe9fab63cbdc7a4dc384d6b2ae84a9 113 Pfam PF00462 Glutaredoxin 17 81 9.7E-18 T 29-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 MC49_RS15700 fdfe9fab63cbdc7a4dc384d6b2ae84a9 113 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 5 101 1.4E-46 T 29-03-2018 IPR004480 Monothiol glutaredoxin-related MC49_RS15700 fdfe9fab63cbdc7a4dc384d6b2ae84a9 113 Gene3D G3DSA:3.40.30.10 3 113 5.7E-30 T 29-03-2018 MC49_RS05535 eadc0b49a4682fab8c378a864a1023e3 152 Gene3D G3DSA:2.70.40.10 114 151 5.4E-16 T 29-03-2018 MC49_RS05535 eadc0b49a4682fab8c378a864a1023e3 152 Pfam PF00692 dUTPase 18 150 8.5E-41 T 29-03-2018 IPR029054 dUTPase-like MC49_RS05535 eadc0b49a4682fab8c378a864a1023e3 152 TIGRFAM TIGR00576 dut: dUTP diphosphatase 13 151 9.0E-49 T 29-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 MC49_RS05535 eadc0b49a4682fab8c378a864a1023e3 152 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 7 151 34.364 T 29-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 MC49_RS05535 eadc0b49a4682fab8c378a864a1023e3 152 SUPERFAMILY SSF51283 1 151 2.75E-55 T 29-03-2018 IPR029054 dUTPase-like MC49_RS05535 eadc0b49a4682fab8c378a864a1023e3 152 Gene3D G3DSA:2.70.40.10 1 113 2.2E-39 T 29-03-2018 MC49_RS02060 0ed0e5e1d1662d693d116fa7dfa5c348 671 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 387 413 4.8E-11 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS02060 0ed0e5e1d1662d693d116fa7dfa5c348 671 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 167 191 4.8E-11 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS02060 0ed0e5e1d1662d693d116fa7dfa5c348 671 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 236 260 4.8E-11 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS02060 0ed0e5e1d1662d693d116fa7dfa5c348 671 Pfam PF00361 Proton-conducting membrane transporter 135 421 9.9E-56 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS14390 e90e44a2f5b680057a5b113bd0392380 315 SUPERFAMILY SSF52402 155 309 2.51E-23 T 29-03-2018 MC49_RS14390 e90e44a2f5b680057a5b113bd0392380 315 Gene3D G3DSA:3.40.50.620 1 154 7.3E-20 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS14390 e90e44a2f5b680057a5b113bd0392380 315 Pfam PF00582 Universal stress protein family 227 301 1.0E-10 T 29-03-2018 IPR006016 UspA GO:0006950 MC49_RS14390 e90e44a2f5b680057a5b113bd0392380 315 Pfam PF00582 Universal stress protein family 4 146 6.9E-19 T 29-03-2018 IPR006016 UspA GO:0006950 MC49_RS14390 e90e44a2f5b680057a5b113bd0392380 315 Gene3D G3DSA:3.40.50.620 155 304 4.4E-19 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS14390 e90e44a2f5b680057a5b113bd0392380 315 SUPERFAMILY SSF52402 4 153 2.01E-26 T 29-03-2018 MC49_RS18260 bae181e9354620ec10e6bbf93bd41bd5 118 ProDom PD075772 YGBA ECS3588 CYTOPLASMIC UVRA STM2860 AMIDOPHOSPHORIBOSYLTRANSFERASE VVA0912 SO0324 VPA0976 CPE0229 1 97 1.0E-34 T 29-03-2018 IPR020483 Uncharacterised protein family YgbA MC49_RS18260 bae181e9354620ec10e6bbf93bd41bd5 118 Pfam PF11756 Nitrous oxide-stimulated promoter 5 105 5.0E-40 T 29-03-2018 IPR020483 Uncharacterised protein family YgbA MC49_RS11905 234c4dc37a4f9723b058dc847c623d68 215 Pfam PF11319 Type VI secretion system VasI, EvfG, VC_A0118 38 215 3.1E-55 T 29-03-2018 IPR017738 Type VI secretion system-associated, VCA0118 MC49_RS11905 234c4dc37a4f9723b058dc847c623d68 215 TIGRFAM TIGR03360 VI_minor_1: type VI secretion-associated protein, VC_A0118 family 37 215 1.2E-55 T 29-03-2018 IPR017738 Type VI secretion system-associated, VCA0118 MC49_RS08100 905f9ca8c27f2fce964bbf6bf30d4168 198 Gene3D G3DSA:3.30.420.10 4 198 4.8E-70 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MC49_RS08100 905f9ca8c27f2fce964bbf6bf30d4168 198 SUPERFAMILY SSF53098 3 194 8.95E-70 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MC49_RS08100 905f9ca8c27f2fce964bbf6bf30d4168 198 Pfam PF01351 Ribonuclease HII 12 187 3.5E-41 T 29-03-2018 IPR024567 Ribonuclease HII/HIII domain MC49_RS08100 905f9ca8c27f2fce964bbf6bf30d4168 198 Hamap MF_00052_B Ribonuclease HII [rnhB]. 10 189 38.714 T 29-03-2018 IPR022898 Ribonuclease HII GO:0004523 MC49_RS08460 db20c161060b8dc7ada3cdb23a1da5c0 261 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 84 117 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 MC49_RS08460 db20c161060b8dc7ada3cdb23a1da5c0 261 Gene3D G3DSA:3.40.1010.10 3 128 1.6E-33 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MC49_RS08460 db20c161060b8dc7ada3cdb23a1da5c0 261 SUPERFAMILY SSF53790 2 239 8.77E-77 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MC49_RS08460 db20c161060b8dc7ada3cdb23a1da5c0 261 Gene3D G3DSA:3.30.950.10 129 256 2.5E-35 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MC49_RS08460 db20c161060b8dc7ada3cdb23a1da5c0 261 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 9 23 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 MC49_RS08460 db20c161060b8dc7ada3cdb23a1da5c0 261 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 215 2.4E-45 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MC49_RS08460 db20c161060b8dc7ada3cdb23a1da5c0 261 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 4 239 1.5E-94 T 29-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 MC49_RS05385 96189b23b4b44f393035a2f31a69b887 977 Gene3D G3DSA:2.170.130.10 54 182 9.2E-12 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MC49_RS05385 96189b23b4b44f393035a2f31a69b887 977 Pfam PF07715 TonB-dependent Receptor Plug Domain 62 155 1.8E-12 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MC49_RS05385 96189b23b4b44f393035a2f31a69b887 977 SUPERFAMILY SSF56935 57 189 6.59E-62 T 29-03-2018 MC49_RS05385 96189b23b4b44f393035a2f31a69b887 977 SUPERFAMILY SSF56935 238 282 6.59E-62 T 29-03-2018 MC49_RS05385 96189b23b4b44f393035a2f31a69b887 977 SUPERFAMILY SSF56935 442 539 6.59E-62 T 29-03-2018 MC49_RS05385 96189b23b4b44f393035a2f31a69b887 977 SUPERFAMILY SSF56935 691 831 6.59E-62 T 29-03-2018 MC49_RS05385 96189b23b4b44f393035a2f31a69b887 977 SUPERFAMILY SSF56935 858 977 6.59E-62 T 29-03-2018 MC49_RS05385 96189b23b4b44f393035a2f31a69b887 977 SUPERFAMILY SSF56935 404 413 6.59E-62 T 29-03-2018 MC49_RS05385 96189b23b4b44f393035a2f31a69b887 977 SUPERFAMILY SSF56935 315 366 6.59E-62 T 29-03-2018 MC49_RS05385 96189b23b4b44f393035a2f31a69b887 977 Pfam PF00593 TonB dependent receptor 689 975 4.7E-31 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MC49_RS05385 96189b23b4b44f393035a2f31a69b887 977 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 960 977 - T 29-03-2018 IPR010917 TonB-dependent receptor, conserved site MC49_RS05385 96189b23b4b44f393035a2f31a69b887 977 Gene3D G3DSA:2.40.170.20 230 977 2.1E-58 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MC49_RS14385 b95dea84579b1cd6f1d1a815773eace4 147 ProDom PD034160 PRECURSOR SIGNAL YFJT INTERGENIC-REGION C0283 YKFB 1 138 9.0E-16 T 29-03-2018 MC49_RS05735 f89cf9c43401aac793d212f8f40c3dc1 229 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 119 152 9.1E-4 T 29-03-2018 IPR001451 Hexapeptide repeat MC49_RS05735 f89cf9c43401aac793d212f8f40c3dc1 229 TIGRFAM TIGR03570 NeuD_NnaD: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family 18 212 1.3E-55 T 29-03-2018 IPR020019 Sialic acid O-acyltransferase NeuD-like MC49_RS05735 f89cf9c43401aac793d212f8f40c3dc1 229 Gene3D G3DSA:2.160.10.10 100 224 2.3E-23 T 29-03-2018 MC49_RS05735 f89cf9c43401aac793d212f8f40c3dc1 229 SUPERFAMILY SSF51161 8 214 1.94E-36 T 29-03-2018 IPR011004 Trimeric LpxA-like MC49_RS05735 f89cf9c43401aac793d212f8f40c3dc1 229 Gene3D G3DSA:3.40.50.20 14 99 7.8E-12 T 29-03-2018 MC49_RS13630 67c23e15beabe18a45e44f6f439fabc6 265 TIGRFAM TIGR00822 EII-Sor: PTS system, mannose/fructose/sorbose family, IIC component 1 265 3.4E-119 T 29-03-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 MC49_RS13630 67c23e15beabe18a45e44f6f439fabc6 265 Pfam PF03609 PTS system sorbose-specific iic component 5 237 4.4E-76 T 29-03-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 MC49_RS18340 2ddd60eb4ee54394dbd191384d4a9c25 88 Pfam PF11391 Protein of unknown function (DUF2798) 26 82 4.1E-17 T 29-03-2018 IPR021529 Protein of unknown function DUF2798 MC49_RS07090 f9a0514852c92a2e9bb03e771aaf3470 177 Pfam PF09335 SNARE associated Golgi protein 41 164 2.9E-16 T 29-03-2018 IPR032816 SNARE associated Golgi protein MC49_RS00545 6c264da203bb440520ec151f68d6caa4 269 Pfam PF01963 TraB family 33 267 1.0E-33 T 29-03-2018 IPR002816 Pheromone shutdown, TraB MC49_RS06815 1db56565ab7e6273f610a7943c985b86 158 Gene3D G3DSA:1.10.530.40 1 158 1.4E-50 T 29-03-2018 IPR023347 Lysozyme domain GO:0003796 MC49_RS06815 1db56565ab7e6273f610a7943c985b86 158 SUPERFAMILY SSF53955 8 157 6.14E-54 T 29-03-2018 IPR023346 Lysozyme-like domain MC49_RS06815 1db56565ab7e6273f610a7943c985b86 158 Pfam PF00959 Phage lysozyme 43 148 2.9E-25 T 29-03-2018 IPR002196 Glycoside hydrolase, family 24 GO:0003796|GO:0009253|GO:0016998 MC49_RS01580 40420952375b9042ae4f79f7ae581a32 241 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 215 236 1.3E-7 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal MC49_RS01580 40420952375b9042ae4f79f7ae581a32 241 Gene3D G3DSA:3.40.50.300 3 236 4.0E-62 T 29-03-2018 MC49_RS01580 40420952375b9042ae4f79f7ae581a32 241 SMART SM00382 28 213 8.2E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS01580 40420952375b9042ae4f79f7ae581a32 241 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 4 241 6.9E-121 T 29-03-2018 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 MC49_RS01580 40420952375b9042ae4f79f7ae581a32 241 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS01580 40420952375b9042ae4f79f7ae581a32 241 Pfam PF00005 ABC transporter 20 166 8.7E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS01580 40420952375b9042ae4f79f7ae581a32 241 SUPERFAMILY SSF52540 5 236 6.05E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS00910 9d7a942d84299c8b687204e69ef345b2 443 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 14 417 1.7E-147 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 MC49_RS00910 9d7a942d84299c8b687204e69ef345b2 443 Pfam PF05525 Branched-chain amino acid transport protein 8 430 9.7E-151 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 MC49_RS03290 fbcf2dea86ea8486685bfae92e5fa34f 106 SUPERFAMILY SSF82771 9 80 1.19E-9 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily MC49_RS03290 fbcf2dea86ea8486685bfae92e5fa34f 106 Pfam PF01541 GIY-YIG catalytic domain 10 80 1.8E-10 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily MC49_RS03290 fbcf2dea86ea8486685bfae92e5fa34f 106 Gene3D G3DSA:3.40.1440.10 2 89 6.0E-5 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily MC49_RS15140 b308d98a1ab44f5d52cd7eef9cf9b8c6 206 SUPERFAMILY SSF55821 1 204 7.94E-63 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain MC49_RS15140 b308d98a1ab44f5d52cd7eef9cf9b8c6 206 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 202 3.0E-71 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 MC49_RS15140 b308d98a1ab44f5d52cd7eef9cf9b8c6 206 Gene3D G3DSA:3.90.870.10 1 205 1.4E-59 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain MC49_RS15140 b308d98a1ab44f5d52cd7eef9cf9b8c6 206 Pfam PF01300 Telomere recombination 23 198 1.0E-45 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 MC49_RS14140 961b464a31e457704c752d144f789e89 234 Gene3D G3DSA:3.40.50.2300 11 130 2.9E-32 T 29-03-2018 MC49_RS14140 961b464a31e457704c752d144f789e89 234 TIGRFAM TIGR01387 cztR_silR_copR: heavy metal response regulator 15 230 9.4E-98 T 29-03-2018 IPR006291 Transcriptional regulatory protein PcoR, heavy metal response GO:0003677|GO:0006355 MC49_RS14140 961b464a31e457704c752d144f789e89 234 SUPERFAMILY SSF52172 12 138 1.71E-38 T 29-03-2018 IPR011006 CheY-like superfamily MC49_RS14140 961b464a31e457704c752d144f789e89 234 SMART SM00448 13 123 4.2E-42 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS14140 961b464a31e457704c752d144f789e89 234 SUPERFAMILY SSF46894 129 231 9.92E-29 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MC49_RS14140 961b464a31e457704c752d144f789e89 234 Gene3D G3DSA:1.10.10.10 131 234 6.1E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS14140 961b464a31e457704c752d144f789e89 234 SMART SM00862 155 230 8.3E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MC49_RS14140 961b464a31e457704c752d144f789e89 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 230 1.3E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MC49_RS14140 961b464a31e457704c752d144f789e89 234 Pfam PF00072 Response regulator receiver domain 15 124 5.9E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS08185 b53e2c199c1d9291fd96a7ebda45f4bf 261 SUPERFAMILY SSF56219 45 260 3.01E-24 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase MC49_RS08185 b53e2c199c1d9291fd96a7ebda45f4bf 261 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 50 253 6.7E-7 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase MC49_RS08185 b53e2c199c1d9291fd96a7ebda45f4bf 261 Gene3D G3DSA:3.60.10.10 38 261 3.4E-18 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase MC49_RS02980 8c88f3bb7b5622de9a666c322a973810 260 Pfam PF01925 Sulfite exporter TauE/SafE 7 255 3.4E-35 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MC49_RS18160 d6aacc92c8c3acf9a38dda3915227674 356 SUPERFAMILY SSF74650 18 354 3.27E-100 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 MC49_RS18160 d6aacc92c8c3acf9a38dda3915227674 356 ProSitePatterns PS00545 Aldose 1-epimerase putative active site. 179 188 - T 29-03-2018 IPR018052 Aldose 1-epimerase, conserved site KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 MC49_RS18160 d6aacc92c8c3acf9a38dda3915227674 356 PIRSF PIRSF005096 10 356 1.1E-105 T 29-03-2018 IPR015443 Aldose 1-epimerase GO:0016853|GO:0019318 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 MC49_RS18160 d6aacc92c8c3acf9a38dda3915227674 356 Gene3D G3DSA:2.70.98.10 13 356 1.9E-102 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 MC49_RS18160 d6aacc92c8c3acf9a38dda3915227674 356 Pfam PF01263 Aldose 1-epimerase 26 353 2.3E-80 T 29-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 MC49_RS09565 45a7c92c6f91d40ce494c229fdf272e7 90 PIRSF PIRSF029827 1 90 1.7E-42 T 29-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 MC49_RS09565 45a7c92c6f91d40ce494c229fdf272e7 90 ProDom PD029191 TRAFFICKING IRON PROBABLE FE2 YGGX FEII 3D-STRUCTURE OXIDATIVE CONTROL DIRECT 1 76 6.0E-35 T 29-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 MC49_RS09565 45a7c92c6f91d40ce494c229fdf272e7 90 SUPERFAMILY SSF111148 1 89 1.22E-38 T 29-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 MC49_RS09565 45a7c92c6f91d40ce494c229fdf272e7 90 Gene3D G3DSA:1.10.3880.10 2 89 1.2E-38 T 29-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 MC49_RS09565 45a7c92c6f91d40ce494c229fdf272e7 90 Pfam PF04362 Bacterial Fe(2+) trafficking 1 88 8.1E-39 T 29-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 MC49_RS09565 45a7c92c6f91d40ce494c229fdf272e7 90 Hamap MF_00686 Probable Fe(2+)-trafficking protein [yggX]. 1 88 27.394 T 29-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 MC49_RS05190 7d3c0d95d9a12ad99efbee28a36f5695 609 Pfam PF01380 SIS domain 292 418 1.4E-31 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MC49_RS05190 7d3c0d95d9a12ad99efbee28a36f5695 609 Pfam PF01380 SIS domain 462 591 2.7E-26 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MC49_RS05190 7d3c0d95d9a12ad99efbee28a36f5695 609 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 609 1.4E-262 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 MC49_RS05190 7d3c0d95d9a12ad99efbee28a36f5695 609 SUPERFAMILY SSF56235 2 234 4.72E-76 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MC49_RS05190 7d3c0d95d9a12ad99efbee28a36f5695 609 Gene3D G3DSA:3.40.50.10490 240 458 3.5E-61 T 29-03-2018 MC49_RS05190 7d3c0d95d9a12ad99efbee28a36f5695 609 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 609 40.979 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 MC49_RS05190 7d3c0d95d9a12ad99efbee28a36f5695 609 Pfam PF13522 Glutamine amidotransferase domain 64 184 2.1E-23 T 29-03-2018 MC49_RS05190 7d3c0d95d9a12ad99efbee28a36f5695 609 Gene3D G3DSA:3.40.50.10490 459 607 7.9E-49 T 29-03-2018 MC49_RS05190 7d3c0d95d9a12ad99efbee28a36f5695 609 SUPERFAMILY SSF53697 245 609 1.21E-112 T 29-03-2018 MC49_RS05190 7d3c0d95d9a12ad99efbee28a36f5695 609 Gene3D G3DSA:3.60.20.10 2 239 7.3E-69 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MC49_RS01180 81a699a2aa7f7669f7eab3c8198dcccd 93 Gene3D G3DSA:1.10.10.10 22 92 2.8E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS01180 81a699a2aa7f7669f7eab3c8198dcccd 93 SUPERFAMILY SSF46955 21 77 8.42E-9 T 29-03-2018 IPR009061 Putative DNA-binding domain MC49_RS01180 81a699a2aa7f7669f7eab3c8198dcccd 93 Pfam PF12728 Helix-turn-helix domain 22 72 7.1E-10 T 29-03-2018 MC49_RS05885 ab6b0fc4c2aa78347f1c9038788fe0a3 71 Pfam PF01197 Ribosomal protein L31 1 64 3.3E-29 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS05885 ab6b0fc4c2aa78347f1c9038788fe0a3 71 PRINTS PR01249 Ribosomal protein L31 signature 31 46 5.2E-22 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS05885 ab6b0fc4c2aa78347f1c9038788fe0a3 71 PRINTS PR01249 Ribosomal protein L31 signature 2 19 5.2E-22 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS05885 ab6b0fc4c2aa78347f1c9038788fe0a3 71 PRINTS PR01249 Ribosomal protein L31 signature 46 64 5.2E-22 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS05885 ab6b0fc4c2aa78347f1c9038788fe0a3 71 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 68 30.341 T 29-03-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS05885 ab6b0fc4c2aa78347f1c9038788fe0a3 71 SUPERFAMILY SSF143800 1 66 1.77E-26 T 29-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MC49_RS05885 ab6b0fc4c2aa78347f1c9038788fe0a3 71 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 65 1.4E-33 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS05885 ab6b0fc4c2aa78347f1c9038788fe0a3 71 ProSitePatterns PS01143 Ribosomal protein L31 signature. 35 56 - T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS14895 f235f94cd8f45e4ef15b56c5ac9f6a23 579 ProSitePatterns PS00211 ABC transporters family signature. 419 433 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS14895 f235f94cd8f45e4ef15b56c5ac9f6a23 579 Gene3D G3DSA:3.40.50.300 1 293 1.2E-47 T 29-03-2018 MC49_RS14895 f235f94cd8f45e4ef15b56c5ac9f6a23 579 Gene3D G3DSA:3.40.50.300 316 576 4.8E-34 T 29-03-2018 MC49_RS14895 f235f94cd8f45e4ef15b56c5ac9f6a23 579 SMART SM00382 29 199 7.6E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS14895 f235f94cd8f45e4ef15b56c5ac9f6a23 579 SMART SM00382 322 491 1.0E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS14895 f235f94cd8f45e4ef15b56c5ac9f6a23 579 Pfam PF00005 ABC transporter 20 154 1.7E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS14895 f235f94cd8f45e4ef15b56c5ac9f6a23 579 Pfam PF00005 ABC transporter 317 447 5.5E-16 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS14895 f235f94cd8f45e4ef15b56c5ac9f6a23 579 SUPERFAMILY SSF52540 3 201 3.35E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS14895 f235f94cd8f45e4ef15b56c5ac9f6a23 579 SUPERFAMILY SSF52540 317 506 3.69E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS16225 e3887ed6d54c58d7c8801774b8e964d3 429 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 329 349 - T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 MC49_RS16225 e3887ed6d54c58d7c8801774b8e964d3 429 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 11 405 7.6E-123 T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 MC49_RS16225 e3887ed6d54c58d7c8801774b8e964d3 429 Pfam PF00860 Permease family 17 383 2.0E-101 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 MC49_RS04965 3f5ec8c6f27cb65e549aacbdad9b9da4 401 Hamap MF_02062 Sodium/glutamate symporter [gltS]. 1 397 23.386 T 29-03-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 MC49_RS04965 3f5ec8c6f27cb65e549aacbdad9b9da4 401 Pfam PF03616 Sodium/glutamate symporter 2 366 6.3E-164 T 29-03-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 MC49_RS04965 3f5ec8c6f27cb65e549aacbdad9b9da4 401 TIGRFAM TIGR00210 gltS: sodium/glutamate symporter 3 396 1.6E-155 T 29-03-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 MC49_RS01155 5c77a5870f556c08106e75e5c76086ab 187 Pfam PF11000 Protein of unknown function (DUF2840) 38 184 7.9E-63 T 29-03-2018 IPR021263 Protein of unknown function DUF2840 MC49_RS01515 1179eb51391c276bc24a0dc3547e9395 421 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 417 44.017 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MC49_RS01515 1179eb51391c276bc24a0dc3547e9395 421 Gene3D G3DSA:3.65.10.10 21 220 2.3E-53 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 MC49_RS01515 1179eb51391c276bc24a0dc3547e9395 421 Gene3D G3DSA:3.65.10.10 221 419 1.3E-47 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 MC49_RS01515 1179eb51391c276bc24a0dc3547e9395 421 SUPERFAMILY SSF55205 1 418 2.13E-144 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 MC49_RS01515 1179eb51391c276bc24a0dc3547e9395 421 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 407 3.0E-120 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 MC49_RS01515 1179eb51391c276bc24a0dc3547e9395 421 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 416 2.5E-184 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MC49_RS00100 a8012dc2ff369b8afa57dc5c48678474 625 SUPERFAMILY SSF101898 322 616 2.62E-18 T 29-03-2018 MC49_RS00100 a8012dc2ff369b8afa57dc5c48678474 625 Gene3D G3DSA:2.120.10.30 477 531 0.0033 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like MC49_RS00100 a8012dc2ff369b8afa57dc5c48678474 625 Gene3D G3DSA:2.120.10.30 201 476 4.4E-13 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like MC49_RS00100 a8012dc2ff369b8afa57dc5c48678474 625 SUPERFAMILY SSF82171 191 415 3.92E-5 T 29-03-2018 MC49_RS00100 a8012dc2ff369b8afa57dc5c48678474 625 Gene3D G3DSA:2.120.10.30 532 625 0.0013 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like MC49_RS00100 a8012dc2ff369b8afa57dc5c48678474 625 Pfam PF01436 NHL repeat 437 461 4.2E-4 T 29-03-2018 IPR001258 NHL repeat GO:0005515 MC49_RS09380 add7e7bbf0f0989f4daf50a4a4eefb32 280 Gene3D G3DSA:3.20.20.120 12 128 7.5E-5 T 29-03-2018 IPR029065 Enolase C-terminal domain-like MC49_RS09380 add7e7bbf0f0989f4daf50a4a4eefb32 280 Gene3D G3DSA:3.20.20.70 129 264 1.2E-17 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS09380 add7e7bbf0f0989f4daf50a4a4eefb32 280 SUPERFAMILY SSF51366 86 261 3.77E-19 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MC49_RS09380 add7e7bbf0f0989f4daf50a4a4eefb32 280 SUPERFAMILY SSF51366 37 55 3.77E-19 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MC49_RS05230 8f4fdd057ffc7b9c562b7521cda1c73e 594 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 23 327 4.7E-11 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MC49_RS05230 8f4fdd057ffc7b9c562b7521cda1c73e 594 SUPERFAMILY SSF52540 247 363 1.29E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS05230 8f4fdd057ffc7b9c562b7521cda1c73e 594 SUPERFAMILY SSF52540 16 158 1.29E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS05230 8f4fdd057ffc7b9c562b7521cda1c73e 594 Gene3D G3DSA:3.40.50.300 14 452 2.7E-18 T 29-03-2018 MC49_RS04465 580e2f25b3410bc03c4c9e88f4728ff7 103 SUPERFAMILY SSF47413 2 76 9.38E-20 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS04465 580e2f25b3410bc03c4c9e88f4728ff7 103 Gene3D G3DSA:1.10.260.40 1 100 1.5E-18 T 29-03-2018 MC49_RS04465 580e2f25b3410bc03c4c9e88f4728ff7 103 SMART SM00530 15 70 6.3E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS04465 580e2f25b3410bc03c4c9e88f4728ff7 103 Pfam PF01381 Helix-turn-helix 19 70 5.1E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS14500 b54f615d634fb70ea9839a2a5f3a5285 88 Gene3D G3DSA:1.10.720.30 14 70 1.9E-30 T 29-03-2018 IPR003034 SAP domain MC49_RS14500 b54f615d634fb70ea9839a2a5f3a5285 88 Pfam PF09905 DNA-binding protein VF530 6 68 2.4E-33 T 29-03-2018 IPR018668 DNA-binding protein VF530-like GO:0003677 MC49_RS18265 9342804a7d73d3a4153523ea987315e4 184 SUPERFAMILY SSF55729 1 170 1.41E-38 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS18265 9342804a7d73d3a4153523ea987315e4 184 Gene3D G3DSA:3.40.630.30 1 184 1.6E-26 T 29-03-2018 MC49_RS18265 9342804a7d73d3a4153523ea987315e4 184 Pfam PF13302 Acetyltransferase (GNAT) domain 8 150 7.6E-32 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MC49_RS05080 f1453c2b685a66bc78b9392e7f4ff460 296 Pfam PF13407 Periplasmic binding protein domain 29 281 5.5E-54 T 29-03-2018 IPR025997 Periplasmic binding protein MC49_RS05080 f1453c2b685a66bc78b9392e7f4ff460 296 Gene3D G3DSA:3.40.50.2300 24 129 1.3E-19 T 29-03-2018 MC49_RS05080 f1453c2b685a66bc78b9392e7f4ff460 296 SUPERFAMILY SSF53822 26 295 3.33E-84 T 29-03-2018 IPR028082 Periplasmic binding protein-like I MC49_RS05080 f1453c2b685a66bc78b9392e7f4ff460 296 Gene3D G3DSA:3.40.50.2300 130 296 1.3E-45 T 29-03-2018 MC49_RS01165 b79117ce78b00e9c87813d7c31db92fa 212 Gene3D G3DSA:3.40.50.300 1 211 1.9E-37 T 29-03-2018 MC49_RS01165 b79117ce78b00e9c87813d7c31db92fa 212 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 184 6.7E-15 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain MC49_RS01165 b79117ce78b00e9c87813d7c31db92fa 212 SUPERFAMILY SSF52540 1 210 6.8E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS01165 b79117ce78b00e9c87813d7c31db92fa 212 PIRSF PIRSF009320 1 211 2.2E-51 T 29-03-2018 MC49_RS12945 7ab0f98a36e6dfb28b90892128bca541 242 SMART SM00382 98 228 9.0E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS12945 7ab0f98a36e6dfb28b90892128bca541 242 Gene3D G3DSA:3.40.50.300 62 231 3.6E-17 T 29-03-2018 MC49_RS12945 7ab0f98a36e6dfb28b90892128bca541 242 Pfam PF01695 IstB-like ATP binding protein 63 219 1.7E-21 T 29-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 MC49_RS12945 7ab0f98a36e6dfb28b90892128bca541 242 PIRSF PIRSF003073 1 242 1.4E-33 T 29-03-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein MC49_RS12945 7ab0f98a36e6dfb28b90892128bca541 242 SUPERFAMILY SSF52540 65 225 2.72E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS17445 ac2f7f08b5842baae81542fe09dbfb9c 185 Pfam PF09618 CRISPR-associated protein (Cas_Csy4) 4 185 8.0E-25 T 29-03-2018 IPR013396 CRISPR-associated endoribonuclease Cas6/Csy4, subtype I-F/YPEST GO:0004519|GO:0043571 MC49_RS17445 ac2f7f08b5842baae81542fe09dbfb9c 185 TIGRFAM TIGR02563 cas_Csy4: CRISPR-associated endoribonuclease Cas6/Csy4, subtype I-F/YPEST 3 112 2.2E-13 T 29-03-2018 IPR013396 CRISPR-associated endoribonuclease Cas6/Csy4, subtype I-F/YPEST GO:0004519|GO:0043571 MC49_RS08345 48aebc1f1067e3c6219f7d5462fe12a2 250 Gene3D G3DSA:3.30.2010.10 56 148 4.2E-18 T 29-03-2018 MC49_RS08345 48aebc1f1067e3c6219f7d5462fe12a2 250 Pfam PF01435 Peptidase family M48 73 244 4.5E-27 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 MC49_RS13655 4237d9d34e6d67e4e116b27ccfcb051c 64 Hamap MF_00507 UPF0181 protein YoaH [yoaH]. 1 58 18.711 T 29-03-2018 IPR005371 Uncharacterised protein family UPF0181 MC49_RS13655 4237d9d34e6d67e4e116b27ccfcb051c 64 ProDom PD026807 UPF0181 YOAH YPTB1650 VV20310 VPA0916 VCA0569 YPO1774/Y2534/YP1619 PLU2693 VVA0806 PM0480 1 45 4.0E-13 T 29-03-2018 IPR005371 Uncharacterised protein family UPF0181 MC49_RS13655 4237d9d34e6d67e4e116b27ccfcb051c 64 Pfam PF03701 Uncharacterised protein family (UPF0181) 1 49 1.5E-26 T 29-03-2018 IPR005371 Uncharacterised protein family UPF0181 MC49_RS08450 ae68d92f0cea44556de90ce4bd31d1fd 319 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 319 103.785 T 29-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 MC49_RS08450 ae68d92f0cea44556de90ce4bd31d1fd 319 Pfam PF03186 CobD/Cbib protein 7 297 1.4E-105 T 29-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 MC49_RS08450 ae68d92f0cea44556de90ce4bd31d1fd 319 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 7 302 9.1E-75 T 29-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 MC49_RS03235 4725d7620dd789c2dd0c8cfd3f0ac673 137 Pfam PF06877 Regulator of ribonuclease activity B 15 116 2.3E-34 T 29-03-2018 IPR009671 Regulator of ribonuclease activity B domain MC49_RS03235 4725d7620dd789c2dd0c8cfd3f0ac673 137 PIRSF PIRSF018193 3 135 2.6E-61 T 29-03-2018 IPR016716 Regulator of ribonuclease activity B MC49_RS03235 4725d7620dd789c2dd0c8cfd3f0ac673 137 SUPERFAMILY SSF89946 7 126 1.44E-40 T 29-03-2018 IPR009671 Regulator of ribonuclease activity B domain MC49_RS03235 4725d7620dd789c2dd0c8cfd3f0ac673 137 Hamap MF_01888 Regulator of ribonuclease activity B [rraB]. 7 120 30.313 T 29-03-2018 IPR016716 Regulator of ribonuclease activity B MC49_RS03235 4725d7620dd789c2dd0c8cfd3f0ac673 137 Gene3D G3DSA:3.30.70.970 7 119 1.7E-39 T 29-03-2018 IPR009671 Regulator of ribonuclease activity B domain MC49_RS08555 f4be1da01063392164ee50e629794b48 254 SUPERFAMILY SSF51182 132 251 1.23E-26 T 29-03-2018 IPR011051 RmlC-like cupin domain MC49_RS08555 f4be1da01063392164ee50e629794b48 254 Gene3D G3DSA:2.60.120.10 98 254 3.0E-29 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MC49_RS08555 f4be1da01063392164ee50e629794b48 254 Pfam PF06249 Ethanolamine utilisation protein EutQ 93 253 6.1E-56 T 29-03-2018 IPR010424 Ethanolamine utilisation EutQ MC49_RS10005 13f7fafb1ac8620acf361cfba15aa7d3 510 Pfam PF07690 Major Facilitator Superfamily 17 411 1.8E-52 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS10005 13f7fafb1ac8620acf361cfba15aa7d3 510 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 13 496 1.2E-202 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 MC49_RS10005 13f7fafb1ac8620acf361cfba15aa7d3 510 PRINTS PR01036 Tetracycline resistance protein TetB signature 203 221 5.3E-5 T 29-03-2018 MC49_RS10005 13f7fafb1ac8620acf361cfba15aa7d3 510 PRINTS PR01036 Tetracycline resistance protein TetB signature 16 40 5.3E-5 T 29-03-2018 MC49_RS10005 13f7fafb1ac8620acf361cfba15aa7d3 510 PRINTS PR01036 Tetracycline resistance protein TetB signature 137 161 5.3E-5 T 29-03-2018 MC49_RS10005 13f7fafb1ac8620acf361cfba15aa7d3 510 PRINTS PR01036 Tetracycline resistance protein TetB signature 107 127 5.3E-5 T 29-03-2018 MC49_RS10005 13f7fafb1ac8620acf361cfba15aa7d3 510 Gene3D G3DSA:1.20.1250.20 10 198 1.7E-33 T 29-03-2018 MC49_RS10005 13f7fafb1ac8620acf361cfba15aa7d3 510 SUPERFAMILY SSF103473 4 194 3.27E-70 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS10005 13f7fafb1ac8620acf361cfba15aa7d3 510 SUPERFAMILY SSF103473 473 498 3.27E-70 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS10005 13f7fafb1ac8620acf361cfba15aa7d3 510 SUPERFAMILY SSF103473 249 421 3.27E-70 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS10005 13f7fafb1ac8620acf361cfba15aa7d3 510 Gene3D G3DSA:1.20.1250.20 253 501 9.3E-31 T 29-03-2018 MC49_RS06695 1becd7b7cb9036c54c739be399697c45 241 Gene3D G3DSA:1.10.150.20 179 241 2.9E-12 T 29-03-2018 MC49_RS06695 1becd7b7cb9036c54c739be399697c45 241 SUPERFAMILY SSF47789 182 239 9.16E-11 T 29-03-2018 MC49_RS06695 1becd7b7cb9036c54c739be399697c45 241 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 183 231 7.2E-11 T 29-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS06695 1becd7b7cb9036c54c739be399697c45 241 Gene3D G3DSA:1.10.3210.10 1 176 6.2E-22 T 29-03-2018 MC49_RS06695 1becd7b7cb9036c54c739be399697c45 241 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 183 239 5.0E-6 T 29-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MC49_RS06695 1becd7b7cb9036c54c739be399697c45 241 SUPERFAMILY SSF109604 1 173 3.45E-37 T 29-03-2018 MC49_RS11075 89697381f11a7f9ae3a4281c3932d2cc 203 TIGRFAM TIGR00547 lolA: outer membrane lipoprotein carrier protein LolA 1 203 6.4E-95 T 29-03-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 MC49_RS11075 89697381f11a7f9ae3a4281c3932d2cc 203 Hamap MF_00240 Outer-membrane lipoprotein carrier protein [lolA]. 8 201 31.779 T 29-03-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 MC49_RS11075 89697381f11a7f9ae3a4281c3932d2cc 203 SUPERFAMILY SSF89392 24 202 2.2E-52 T 29-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX MC49_RS11075 89697381f11a7f9ae3a4281c3932d2cc 203 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 33 191 3.2E-54 T 29-03-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like MC49_RS11075 89697381f11a7f9ae3a4281c3932d2cc 203 Gene3D G3DSA:2.50.20.10 19 202 3.7E-36 T 29-03-2018 MC49_RS01040 d78b6af15d3cecc4c9dbee6eb798f0ba 330 TIGRFAM TIGR02775 TrbG_Ti: P-type conjugative transfer protein TrbG 104 311 1.0E-89 T 29-03-2018 IPR014142 P-type conjugative transfer protein TrbG MC49_RS01040 d78b6af15d3cecc4c9dbee6eb798f0ba 330 Pfam PF03524 Conjugal transfer protein 103 323 1.0E-63 T 29-03-2018 IPR010258 Conjugal transfer, TrbG/VirB9/CagX MC49_RS13385 427aa4e4e2eb5d3fa5f73be54fe420ff 656 Gene3D G3DSA:1.20.120.330 3 164 0.0041 T 29-03-2018 MC49_RS13385 427aa4e4e2eb5d3fa5f73be54fe420ff 656 Gene3D G3DSA:1.20.5.1230 189 544 3.4E-9 T 29-03-2018 MC49_RS15790 31da68ee0d235a9c65784a560a4949f9 360 Gene3D G3DSA:3.10.350.10 35 88 1.6E-8 T 29-03-2018 MC49_RS15790 31da68ee0d235a9c65784a560a4949f9 360 SMART SM00257 39 85 6.4E-5 T 29-03-2018 IPR018392 LysM domain MC49_RS15790 31da68ee0d235a9c65784a560a4949f9 360 Pfam PF01476 LysM domain 42 85 2.8E-5 T 29-03-2018 IPR018392 LysM domain MC49_RS15790 31da68ee0d235a9c65784a560a4949f9 360 Gene3D G3DSA:2.40.440.10 90 234 6.1E-29 T 29-03-2018 MC49_RS15790 31da68ee0d235a9c65784a560a4949f9 360 SUPERFAMILY SSF141523 94 232 2.22E-27 T 29-03-2018 MC49_RS15790 31da68ee0d235a9c65784a560a4949f9 360 Pfam PF03734 L,D-transpeptidase catalytic domain 98 232 1.1E-17 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 MC49_RS14740 f1adb222b1b5a7a1bf1c6d25d5d749b2 131 SUPERFAMILY SSF54593 4 122 4.56E-22 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MC49_RS14740 f1adb222b1b5a7a1bf1c6d25d5d749b2 131 Gene3D G3DSA:3.10.180.10 7 128 5.8E-24 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MC49_RS14740 f1adb222b1b5a7a1bf1c6d25d5d749b2 131 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 122 5.9E-9 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MC49_RS15175 fa997d8a353e8a6526cc0900ecf12305 268 Gene3D G3DSA:3.20.20.70 2 268 4.8E-67 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS15175 fa997d8a353e8a6526cc0900ecf12305 268 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 8 263 1.5E-96 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MC49_RS15175 fa997d8a353e8a6526cc0900ecf12305 268 SUPERFAMILY SSF51366 1 266 2.83E-86 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 MC49_RS15175 fa997d8a353e8a6526cc0900ecf12305 268 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 14 265 36.528 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MC49_RS15175 fa997d8a353e8a6526cc0900ecf12305 268 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 48 61 - T 29-03-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MC49_RS15175 fa997d8a353e8a6526cc0900ecf12305 268 Pfam PF00290 Tryptophan synthase alpha chain 8 266 2.5E-93 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MC49_RS08315 88cce04857cc5e7399a40aa9cbe795e1 313 SUPERFAMILY SSF53474 35 287 1.71E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS08315 88cce04857cc5e7399a40aa9cbe795e1 313 Gene3D G3DSA:3.40.50.1820 33 313 1.2E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS08315 88cce04857cc5e7399a40aa9cbe795e1 313 Pfam PF12146 Serine aminopeptidase, S33 75 276 2.4E-16 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 MC49_RS01450 e62be324d8b3a19ebd7faeb677ea318f 216 SUPERFAMILY SSF52833 11 110 6.69E-24 T 29-03-2018 IPR012336 Thioredoxin-like fold MC49_RS01450 e62be324d8b3a19ebd7faeb677ea318f 216 SUPERFAMILY SSF47616 82 211 1.25E-27 T 29-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like MC49_RS01450 e62be324d8b3a19ebd7faeb677ea318f 216 Gene3D G3DSA:1.20.1050.10 98 195 2.4E-16 T 29-03-2018 MC49_RS01450 e62be324d8b3a19ebd7faeb677ea318f 216 Pfam PF02798 Glutathione S-transferase, N-terminal domain 10 81 2.8E-17 T 29-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MC49_RS01450 e62be324d8b3a19ebd7faeb677ea318f 216 Pfam PF00043 Glutathione S-transferase, C-terminal domain 102 197 1.3E-12 T 29-03-2018 IPR004046 Glutathione S-transferase, C-terminal MC49_RS01450 e62be324d8b3a19ebd7faeb677ea318f 216 Gene3D G3DSA:3.40.30.10 2 97 5.2E-25 T 29-03-2018 MC49_RS06380 15aa8035933f188664ccd5f1fd6184f1 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 5.1E-71 T 29-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 MC49_RS06380 15aa8035933f188664ccd5f1fd6184f1 156 PIRSF PIRSF002122 3 156 1.4E-63 T 29-03-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 MC49_RS06380 15aa8035933f188664ccd5f1fd6184f1 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 7.8E-65 T 29-03-2018 IPR023798 Ribosomal protein S7 domain MC49_RS06380 15aa8035933f188664ccd5f1fd6184f1 156 SUPERFAMILY SSF47973 6 149 1.31E-59 T 29-03-2018 IPR023798 Ribosomal protein S7 domain MC49_RS06380 15aa8035933f188664ccd5f1fd6184f1 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.115 T 29-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 MC49_RS06380 15aa8035933f188664ccd5f1fd6184f1 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 29-03-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS06380 15aa8035933f188664ccd5f1fd6184f1 156 Gene3D G3DSA:1.10.455.10 6 156 3.6E-61 T 29-03-2018 IPR023798 Ribosomal protein S7 domain MC49_RS13350 5bea28e12be9e452b665c3dbc66b43d1 228 Pfam PF14485 Domain of unknown function (DUF4431) 172 216 4.9E-16 T 29-03-2018 IPR027826 Domain of unknown function DUF4431 MC49_RS12415 792ce034aa86cec3fcaf1e4b5fa3baa2 117 SUPERFAMILY SSF63592 4 99 6.8E-36 T 29-03-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 MC49_RS12415 792ce034aa86cec3fcaf1e4b5fa3baa2 117 ProDom PD015582 ACTIVATOR TRANSCRIPTIONAL TRANSCRIPTION FLAGELLUM FLHD FLAGELLAR DNA-BINDING REGULATION REGULATOR PROBABLE 10 99 2.0E-37 T 29-03-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 MC49_RS12415 792ce034aa86cec3fcaf1e4b5fa3baa2 117 Gene3D G3DSA:1.10.4000.10 4 103 3.2E-42 T 29-03-2018 MC49_RS12415 792ce034aa86cec3fcaf1e4b5fa3baa2 117 Hamap MF_00725 Flagellar transcriptional regulator FlhD [flhD]. 2 105 26.488 T 29-03-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 MC49_RS12415 792ce034aa86cec3fcaf1e4b5fa3baa2 117 Pfam PF05247 Flagellar transcriptional activator (FlhD) 3 101 1.6E-37 T 29-03-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 MC49_RS11650 f33c8760f6b08a879bb9091bd2f6ce6f 167 SUPERFAMILY SSF55729 4 162 8.48E-41 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS11650 f33c8760f6b08a879bb9091bd2f6ce6f 167 Gene3D G3DSA:3.40.630.30 1 167 1.1E-38 T 29-03-2018 MC49_RS11650 f33c8760f6b08a879bb9091bd2f6ce6f 167 Pfam PF00583 Acetyltransferase (GNAT) family 34 137 2.0E-20 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MC49_RS14635 efd709a444fbb31fec568bea418bc5cc 151 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site MC49_RS14635 efd709a444fbb31fec568bea418bc5cc 151 Gene3D G3DSA:3.30.70.920 53 138 8.3E-22 T 29-03-2018 MC49_RS14635 efd709a444fbb31fec568bea418bc5cc 151 SUPERFAMILY SSF54909 61 150 8.58E-18 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel MC49_RS14635 efd709a444fbb31fec568bea418bc5cc 151 Gene3D G3DSA:1.10.10.10 1 52 7.7E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS14635 efd709a444fbb31fec568bea418bc5cc 151 Pfam PF01037 Lrp/AsnC ligand binding domain 67 140 5.6E-20 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MC49_RS14635 efd709a444fbb31fec568bea418bc5cc 151 SUPERFAMILY SSF46785 1 60 4.83E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS14635 efd709a444fbb31fec568bea418bc5cc 151 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 47 2.6E-18 T 29-03-2018 MC49_RS14635 efd709a444fbb31fec568bea418bc5cc 151 SMART SM00344 1 110 1.4E-39 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MC49_RS14635 efd709a444fbb31fec568bea418bc5cc 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 2.2E-16 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MC49_RS14635 efd709a444fbb31fec568bea418bc5cc 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 2.2E-16 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MC49_RS14635 efd709a444fbb31fec568bea418bc5cc 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 2.2E-16 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 MC49_RS00795 1040366a2228b9fae61df1318af7bef6 110 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 20 93 9.7E-17 T 29-03-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 MC49_RS00795 1040366a2228b9fae61df1318af7bef6 110 TIGRFAM TIGR02847 CyoD: cytochrome o ubiquinol oxidase subunit IV 13 108 1.8E-38 T 29-03-2018 IPR014210 Cytochrome o ubiquinol oxidase subunit IV GO:0008827|GO:0015990|GO:0016021 MC49_RS10980 b8b3a920872a93cb9240a2b41ab2d3ee 224 SUPERFAMILY SSF161098 10 203 5.49E-28 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS10980 b8b3a920872a93cb9240a2b41ab2d3ee 224 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 38 217 1.3E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS10980 b8b3a920872a93cb9240a2b41ab2d3ee 224 Gene3D G3DSA:1.10.3720.10 3 223 1.7E-30 T 29-03-2018 MC49_RS10980 b8b3a920872a93cb9240a2b41ab2d3ee 224 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 9 109 1.4E-12 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 MC49_RS00400 ab62f26508ff9d2be444f01b9546d79d 117 Pfam PF10765 Protein of unknown function (DUF2591) 3 110 9.7E-16 T 29-03-2018 IPR019701 Bacteriophage P22, NinX MC49_RS04100 4299aec23bf7a1521fa4f7f99652b488 179 SUPERFAMILY SSF55282 4 179 1.13E-79 T 29-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04100 4299aec23bf7a1521fa4f7f99652b488 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 2.7E-41 T 29-03-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04100 4299aec23bf7a1521fa4f7f99652b488 179 PIRSF PIRSF002161 1 179 3.2E-67 T 29-03-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04100 4299aec23bf7a1521fa4f7f99652b488 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 44.845 T 29-03-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS04100 4299aec23bf7a1521fa4f7f99652b488 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 29-03-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04100 4299aec23bf7a1521fa4f7f99652b488 179 Pfam PF00281 Ribosomal protein L5 24 80 9.9E-29 T 29-03-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04100 4299aec23bf7a1521fa4f7f99652b488 179 Gene3D G3DSA:3.30.1440.10 1 179 1.1E-81 T 29-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS03500 3d7e4920ab3b9fb553415142edeef27a 1256 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 922 1256 5.1E-68 T 29-03-2018 IPR007452 Translocation and assembly module TamB MC49_RS13735 c20b082e3c47d5d191220192b363ea4f 73 Pfam PF10769 Protein of unknown function (DUF2594) 2 73 3.7E-36 T 29-03-2018 MC49_RS12270 5df754de8ce85795d905df6074bacce3 150 Gene3D G3DSA:3.40.630.30 1 147 1.8E-25 T 29-03-2018 MC49_RS12270 5df754de8ce85795d905df6074bacce3 150 Pfam PF13673 Acetyltransferase (GNAT) domain 52 129 1.1E-15 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MC49_RS12270 5df754de8ce85795d905df6074bacce3 150 SUPERFAMILY SSF55729 1 140 2.06E-24 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS07610 4a9399970ddbe3747172ef4771ecf892 173 ProSitePatterns PS00855 Signal peptidases II signature. 104 116 - T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MC49_RS07610 4a9399970ddbe3747172ef4771ecf892 173 Pfam PF01252 Signal peptidase (SPase) II 16 156 1.6E-38 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MC49_RS07610 4a9399970ddbe3747172ef4771ecf892 173 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 7 162 17.559 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MC49_RS07610 4a9399970ddbe3747172ef4771ecf892 173 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 101 116 1.1E-17 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MC49_RS07610 4a9399970ddbe3747172ef4771ecf892 173 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 137 153 1.1E-17 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MC49_RS07610 4a9399970ddbe3747172ef4771ecf892 173 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 53 61 1.1E-17 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MC49_RS07610 4a9399970ddbe3747172ef4771ecf892 173 TIGRFAM TIGR00077 lspA: signal peptidase II 2 163 1.9E-53 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MC49_RS18310 4a9a367976582b16decfc05bc97ac81f 91 Gene3D G3DSA:3.30.70.100 1 91 3.7E-11 T 29-03-2018 MC49_RS18310 4a9a367976582b16decfc05bc97ac81f 91 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 60 1.9E-7 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain MC49_RS18310 4a9a367976582b16decfc05bc97ac81f 91 SUPERFAMILY SSF54909 1 60 8.67E-17 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel MC49_RS06080 908d582952cd6de5199fa0ad880162ed 205 Pfam PF03458 UPF0126 domain 91 162 4.3E-21 T 29-03-2018 IPR005115 Uncharacterised domain UPF0126 MC49_RS06080 908d582952cd6de5199fa0ad880162ed 205 Pfam PF03458 UPF0126 domain 5 78 8.7E-19 T 29-03-2018 IPR005115 Uncharacterised domain UPF0126 MC49_RS09240 ff5169fff984db382bfa6a1f6b25741e 445 Pfam PF00860 Permease family 18 396 5.1E-77 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 MC49_RS09240 ff5169fff984db382bfa6a1f6b25741e 445 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 15 432 4.6E-88 T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 MC49_RS13780 e6665942b562e8573a47ec23f6eeb59f 332 SUPERFAMILY SSF54060 28 242 2.71E-77 T 29-03-2018 MC49_RS13780 e6665942b562e8573a47ec23f6eeb59f 332 Pfam PF04231 Endonuclease I 33 241 4.3E-52 T 29-03-2018 IPR007346 Endonuclease I GO:0004518 MC49_RS13780 e6665942b562e8573a47ec23f6eeb59f 332 SUPERFAMILY SSF57884 277 330 2.62E-10 T 29-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 MC49_RS13780 e6665942b562e8573a47ec23f6eeb59f 332 Gene3D G3DSA:3.40.10.10 219 332 1.3E-18 T 29-03-2018 IPR035451 Ada-like domain MC49_RS13780 e6665942b562e8573a47ec23f6eeb59f 332 Pfam PF02805 Metal binding domain of Ada 277 330 7.1E-7 T 29-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 MC49_RS01980 a03f74e3d2e35d622fe7b6ebc1681592 303 SUPERFAMILY SSF103481 209 292 1.14E-8 T 29-03-2018 MC49_RS01980 a03f74e3d2e35d622fe7b6ebc1681592 303 Pfam PF00892 EamA-like transporter family 6 130 2.3E-17 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MC49_RS01980 a03f74e3d2e35d622fe7b6ebc1681592 303 Pfam PF00892 EamA-like transporter family 146 288 1.5E-14 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MC49_RS01980 a03f74e3d2e35d622fe7b6ebc1681592 303 SUPERFAMILY SSF103481 40 134 1.03E-10 T 29-03-2018 MC49_RS15520 8c1f852ea360067d8affb3fd4665a877 430 Gene3D G3DSA:3.40.50.1000 242 392 1.8E-7 T 29-03-2018 IPR023214 HAD-like domain MC49_RS15520 8c1f852ea360067d8affb3fd4665a877 430 SUPERFAMILY SSF56784 39 109 1.33E-25 T 29-03-2018 IPR023214 HAD-like domain MC49_RS15520 8c1f852ea360067d8affb3fd4665a877 430 SUPERFAMILY SSF56784 137 218 1.33E-25 T 29-03-2018 IPR023214 HAD-like domain MC49_RS15520 8c1f852ea360067d8affb3fd4665a877 430 SUPERFAMILY SSF56784 252 375 1.33E-25 T 29-03-2018 IPR023214 HAD-like domain MC49_RS00900 8a0c8d3a41b20190283cfd5aa6bb1f95 195 Pfam PF04336 Acyl carrier protein phosphodiesterase 81 185 7.6E-29 T 29-03-2018 IPR007431 Acyl carrier protein phosphodiesterase GO:0006633|GO:0008770 KEGG: 00770+3.1.4.14|MetaCyc: PWY-6012 MC49_RS00900 8a0c8d3a41b20190283cfd5aa6bb1f95 195 PIRSF PIRSF011489 1 193 1.8E-75 T 29-03-2018 IPR007431 Acyl carrier protein phosphodiesterase GO:0006633|GO:0008770 KEGG: 00770+3.1.4.14|MetaCyc: PWY-6012 MC49_RS03785 6baf4d26aa473966530a1e5ede8ddfc2 451 Hamap MF_01003 Probable ECA polymerase [wzyE]. 1 448 37.953 T 29-03-2018 IPR010691 Probable ECA polymerase WzyE GO:0009246|GO:0016021 MC49_RS03785 6baf4d26aa473966530a1e5ede8ddfc2 451 Pfam PF06899 WzyE protein, O-antigen assembly polymerase 1 440 1.2E-242 T 29-03-2018 IPR010691 Probable ECA polymerase WzyE GO:0009246|GO:0016021 MC49_RS01420 dc011f81868519dc7b0ed8cc3cef21c8 240 Pfam PF00912 Transglycosylase 56 224 1.2E-50 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 MC49_RS01420 dc011f81868519dc7b0ed8cc3cef21c8 240 TIGRFAM TIGR02070 mono_pep_trsgly: monofunctional biosynthetic peptidoglycan transglycosylase 8 226 4.5E-81 T 29-03-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 MC49_RS01420 dc011f81868519dc7b0ed8cc3cef21c8 240 Gene3D G3DSA:1.10.3810.10 41 237 7.9E-56 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 MC49_RS01420 dc011f81868519dc7b0ed8cc3cef21c8 240 Hamap MF_00766 Monofunctional biosynthetic peptidoglycan transglycosylase [mtgA]. 4 229 42.271 T 29-03-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 MC49_RS01420 dc011f81868519dc7b0ed8cc3cef21c8 240 SUPERFAMILY SSF53955 45 227 1.29E-59 T 29-03-2018 IPR023346 Lysozyme-like domain MC49_RS05100 d6fbc7f57f57d5a7c50c59c588cf971d 191 Gene3D G3DSA:2.70.50.50 22 191 1.4E-53 T 29-03-2018 MC49_RS05100 d6fbc7f57f57d5a7c50c59c588cf971d 191 SUPERFAMILY SSF81296 22 191 2.66E-54 T 29-03-2018 IPR014756 Immunoglobulin E-set MC49_RS05100 d6fbc7f57f57d5a7c50c59c588cf971d 191 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 22 188 1.9E-33 T 29-03-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal MC49_RS11770 9dbd5199de97891175837f7d19cc77cd 272 SUPERFAMILY SSF53474 48 218 1.2E-12 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS11770 9dbd5199de97891175837f7d19cc77cd 272 Gene3D G3DSA:3.40.50.1820 43 264 9.0E-14 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS04335 aa3cc0a01f0c98a1b749047dc9421c79 86 Gene3D G3DSA:2.20.28.20 59 86 4.1E-4 T 29-03-2018 MC49_RS15815 63dd0edc68ee1a71a522518b8bf1618d 494 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 21 485 3.3E-195 T 29-03-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 MC49_RS15815 63dd0edc68ee1a71a522518b8bf1618d 494 Pfam PF01458 Uncharacterized protein family (UPF0051) 233 465 7.7E-69 T 29-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 MC49_RS15815 63dd0edc68ee1a71a522518b8bf1618d 494 SUPERFAMILY SSF101960 124 491 8.24E-136 T 29-03-2018 MC49_RS15815 63dd0edc68ee1a71a522518b8bf1618d 494 SUPERFAMILY SSF101960 41 86 8.24E-136 T 29-03-2018 MC49_RS10120 68e09dc80682a29348bfbc5e7c8d21cf 108 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 6 108 24.01 T 29-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS MC49_RS10120 68e09dc80682a29348bfbc5e7c8d21cf 108 SUPERFAMILY SSF81301 7 108 6.54E-36 T 29-03-2018 MC49_RS10120 68e09dc80682a29348bfbc5e7c8d21cf 108 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 10 107 2.3E-36 T 29-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS MC49_RS10120 68e09dc80682a29348bfbc5e7c8d21cf 108 Gene3D G3DSA:3.30.460.10 4 108 1.1E-33 T 29-03-2018 MC49_RS10120 68e09dc80682a29348bfbc5e7c8d21cf 108 Pfam PF02410 Ribosomal silencing factor during starvation 13 107 9.0E-28 T 29-03-2018 MC49_RS09110 be4b4bd85a58e80f4b8b35a4b85b0c20 426 Pfam PF00202 Aminotransferase class-III 32 396 3.0E-79 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MC49_RS09110 be4b4bd85a58e80f4b8b35a4b85b0c20 426 SUPERFAMILY SSF53383 2 426 5.09E-138 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS09110 be4b4bd85a58e80f4b8b35a4b85b0c20 426 Gene3D G3DSA:3.40.640.10 181 311 4.7E-47 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS09110 be4b4bd85a58e80f4b8b35a4b85b0c20 426 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 4 425 1.3E-198 T 29-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 MC49_RS09110 be4b4bd85a58e80f4b8b35a4b85b0c20 426 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 3 426 106.577 T 29-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 MC49_RS09110 be4b4bd85a58e80f4b8b35a4b85b0c20 426 Gene3D G3DSA:3.90.1150.10 312 426 5.1E-20 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS09110 be4b4bd85a58e80f4b8b35a4b85b0c20 426 Gene3D G3DSA:3.90.1150.10 1 180 8.6E-45 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS09110 be4b4bd85a58e80f4b8b35a4b85b0c20 426 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 234 270 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MC49_RS07775 6c81fb2defa64c3af461a9e2480a4963 164 SUPERFAMILY SSF53597 1 162 1.07E-56 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 MC49_RS07775 6c81fb2defa64c3af461a9e2480a4963 164 Gene3D G3DSA:3.40.430.10 1 164 4.9E-55 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 MC49_RS07775 6c81fb2defa64c3af461a9e2480a4963 164 PIRSF PIRSF000194 1 164 1.2E-57 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 MC49_RS07775 6c81fb2defa64c3af461a9e2480a4963 164 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 14 36 - T 29-03-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 MC49_RS07775 6c81fb2defa64c3af461a9e2480a4963 164 Pfam PF00186 Dihydrofolate reductase 3 161 7.5E-57 T 29-03-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 MC49_RS07775 6c81fb2defa64c3af461a9e2480a4963 164 PRINTS PR00070 Dihydrofolate reductase signature 28 36 9.5E-13 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 MC49_RS07775 6c81fb2defa64c3af461a9e2480a4963 164 PRINTS PR00070 Dihydrofolate reductase signature 41 52 9.5E-13 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 MC49_RS07775 6c81fb2defa64c3af461a9e2480a4963 164 PRINTS PR00070 Dihydrofolate reductase signature 93 107 9.5E-13 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 MC49_RS07775 6c81fb2defa64c3af461a9e2480a4963 164 PRINTS PR00070 Dihydrofolate reductase signature 14 24 9.5E-13 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 MC49_RS02405 9e4ce0a417acb93550ab8e7192770525 194 Pfam PF00419 Fimbrial protein 45 194 7.6E-17 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS02405 9e4ce0a417acb93550ab8e7192770525 194 SUPERFAMILY SSF49401 44 194 1.69E-32 T 29-03-2018 IPR008966 Adhesion domain MC49_RS02405 9e4ce0a417acb93550ab8e7192770525 194 Gene3D G3DSA:2.60.40.1090 43 194 1.4E-29 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS05440 a5b602178b51bce0e2dc8635b296aae4 460 Pfam PF12390 Selenocysteine synthase N terminal 7 46 1.4E-7 T 29-03-2018 IPR025862 L-seryl-tRNA selenium transferase N-terminal domain KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 MC49_RS05440 a5b602178b51bce0e2dc8635b296aae4 460 TIGRFAM TIGR00474 selA: L-seryl-tRNA(Sec) selenium transferase 8 457 8.9E-179 T 29-03-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 MC49_RS05440 a5b602178b51bce0e2dc8635b296aae4 460 Hamap MF_00423 L-seryl-tRNA(Sec) selenium transferase [selA]. 1 460 232.906 T 29-03-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 MC49_RS05440 a5b602178b51bce0e2dc8635b296aae4 460 Gene3D G3DSA:3.40.640.10 99 344 3.4E-32 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS05440 a5b602178b51bce0e2dc8635b296aae4 460 SUPERFAMILY SSF53383 71 458 8.0E-46 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS05440 a5b602178b51bce0e2dc8635b296aae4 460 Pfam PF03841 L-seryl-tRNA selenium transferase 80 448 1.4E-167 T 29-03-2018 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 MC49_RS04590 8404241c89afbd499297d0d0626a9a1f 339 Gene3D G3DSA:3.40.50.1100 162 336 2.1E-27 T 29-03-2018 MC49_RS04590 8404241c89afbd499297d0d0626a9a1f 339 PIRSF PIRSF006278 7 338 4.0E-92 T 29-03-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase MC49_RS04590 8404241c89afbd499297d0d0626a9a1f 339 TIGRFAM TIGR01275 ACC_deam_rel: pyridoxal phosphate-dependent enzymes, D-cysteine desulfhydrase family 25 333 1.3E-108 T 29-03-2018 IPR005966 D-cysteine desulfhydrase GO:0003824 KEGG: 00270+4.4.1.15 MC49_RS04590 8404241c89afbd499297d0d0626a9a1f 339 SUPERFAMILY SSF53686 22 335 5.11E-79 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MC49_RS04590 8404241c89afbd499297d0d0626a9a1f 339 Gene3D G3DSA:3.40.50.1100 61 161 2.5E-25 T 29-03-2018 MC49_RS04590 8404241c89afbd499297d0d0626a9a1f 339 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 26 324 1.1E-50 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme MC49_RS06705 9444165db34492568e0c9fb687dffb16 275 Pfam PF10065 Uncharacterized conserved protein (DUF2303) 6 273 1.1E-89 T 29-03-2018 IPR019276 Protein of unkown function DUF2303 MC49_RS04085 8445f7e351ce625094566fdf26e23573 177 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 36.209 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MC49_RS04085 8445f7e351ce625094566fdf26e23573 177 PRINTS PR00059 Ribosomal protein L6 signature 71 96 1.7E-33 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MC49_RS04085 8445f7e351ce625094566fdf26e23573 177 PRINTS PR00059 Ribosomal protein L6 signature 99 115 1.7E-33 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MC49_RS04085 8445f7e351ce625094566fdf26e23573 177 PRINTS PR00059 Ribosomal protein L6 signature 141 162 1.7E-33 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MC49_RS04085 8445f7e351ce625094566fdf26e23573 177 Gene3D G3DSA:3.90.930.12 5 85 3.1E-26 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04085 8445f7e351ce625094566fdf26e23573 177 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 29-03-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MC49_RS04085 8445f7e351ce625094566fdf26e23573 177 SUPERFAMILY SSF56053 1 82 3.01E-24 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04085 8445f7e351ce625094566fdf26e23573 177 Gene3D G3DSA:3.90.930.12 86 177 1.6E-38 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04085 8445f7e351ce625094566fdf26e23573 177 PIRSF PIRSF002162 1 177 6.2E-45 T 29-03-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04085 8445f7e351ce625094566fdf26e23573 177 Pfam PF00347 Ribosomal protein L6 11 82 1.1E-18 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04085 8445f7e351ce625094566fdf26e23573 177 Pfam PF00347 Ribosomal protein L6 90 164 2.5E-18 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04085 8445f7e351ce625094566fdf26e23573 177 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 1.6E-73 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MC49_RS04085 8445f7e351ce625094566fdf26e23573 177 SUPERFAMILY SSF56053 83 177 2.1E-35 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS04500 25c582063ef87cca57a32c8a1caba1c4 110 SMART SM00530 14 69 2.5E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS04500 25c582063ef87cca57a32c8a1caba1c4 110 Pfam PF01381 Helix-turn-helix 15 67 2.2E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS04500 25c582063ef87cca57a32c8a1caba1c4 110 SUPERFAMILY SSF47413 5 73 2.31E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS04500 25c582063ef87cca57a32c8a1caba1c4 110 Gene3D G3DSA:1.10.260.40 1 79 8.1E-20 T 29-03-2018 MC49_RS04880 7e3670465fe2ba9b4da086f4255d15c6 224 Gene3D G3DSA:1.10.10.10 1 69 1.9E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS04880 7e3670465fe2ba9b4da086f4255d15c6 224 Pfam PF13280 WYL domain 131 197 3.0E-7 T 29-03-2018 IPR026881 WYL domain MC49_RS07795 ca05e1bb1a137dfd74ed302cad3f990e 332 Gene3D G3DSA:3.40.718.10 1 332 7.8E-131 T 29-03-2018 MC49_RS07795 ca05e1bb1a137dfd74ed302cad3f990e 332 SUPERFAMILY SSF53659 8 331 1.82E-114 T 29-03-2018 MC49_RS07795 ca05e1bb1a137dfd74ed302cad3f990e 332 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 6 328 35.209 T 29-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 MC49_RS07795 ca05e1bb1a137dfd74ed302cad3f990e 332 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 37 324 7.8E-107 T 29-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 MC49_RS07795 ca05e1bb1a137dfd74ed302cad3f990e 332 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 10 327 1.3E-127 T 29-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 MC49_RS02330 41cebd0b4dd6308a5d168ad58d909fc8 314 SUPERFAMILY SSF161098 93 290 4.97E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS02330 41cebd0b4dd6308a5d168ad58d909fc8 314 TIGRFAM TIGR02789 nickel_nikB: nickel ABC transporter, permease subunit NikB 1 308 2.5E-146 T 29-03-2018 IPR014156 Nickel ABC transporter, permease subunit NikB GO:0015099|GO:0035444 MC49_RS02330 41cebd0b4dd6308a5d168ad58d909fc8 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 307 6.1E-45 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS02330 41cebd0b4dd6308a5d168ad58d909fc8 314 Gene3D G3DSA:1.10.3720.10 2 296 2.1E-48 T 29-03-2018 MC49_RS06545 11622c8a94e562c24a680feec5e599b8 218 Gene3D G3DSA:2.130.10.10 10 217 5.7E-4 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MC49_RS06545 11622c8a94e562c24a680feec5e599b8 218 Pfam PF07356 Protein of unknown function (DUF1481) 29 214 1.7E-67 T 29-03-2018 IPR010858 Protein of unknown function DUF1481 MC49_RS05595 c2cb4e046d45c5664003a12b27be22f3 357 TIGRFAM TIGR02201 heptsyl_trn_III: putative lipopolysaccharide heptosyltransferase III 10 356 4.6E-148 T 29-03-2018 IPR011916 Lipopolysaccharide heptosyltransferase III, putative MC49_RS05595 c2cb4e046d45c5664003a12b27be22f3 357 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 83 330 7.6E-51 T 29-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 MC49_RS05595 c2cb4e046d45c5664003a12b27be22f3 357 SUPERFAMILY SSF53756 9 357 1.73E-83 T 29-03-2018 MC49_RS05595 c2cb4e046d45c5664003a12b27be22f3 357 Gene3D G3DSA:3.40.50.2000 173 357 1.8E-43 T 29-03-2018 MC49_RS05595 c2cb4e046d45c5664003a12b27be22f3 357 Gene3D G3DSA:3.40.50.2000 1 172 1.8E-37 T 29-03-2018 MC49_RS06020 d8ccdb36a1d719e0dc2536cc08e55757 205 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 146 166 1.4E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MC49_RS06020 d8ccdb36a1d719e0dc2536cc08e55757 205 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 96 109 1.4E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MC49_RS06020 d8ccdb36a1d719e0dc2536cc08e55757 205 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 128 144 1.4E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MC49_RS06020 d8ccdb36a1d719e0dc2536cc08e55757 205 SUPERFAMILY SSF56784 3 191 6.08E-43 T 29-03-2018 IPR023214 HAD-like domain MC49_RS06020 d8ccdb36a1d719e0dc2536cc08e55757 205 Gene3D G3DSA:3.40.50.1000 75 204 1.0E-19 T 29-03-2018 IPR023214 HAD-like domain MC49_RS06020 d8ccdb36a1d719e0dc2536cc08e55757 205 Gene3D G3DSA:1.10.150.240 12 74 1.1E-16 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 MC49_RS06020 d8ccdb36a1d719e0dc2536cc08e55757 205 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 72 184 3.3E-17 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 MC49_RS06020 d8ccdb36a1d719e0dc2536cc08e55757 205 Pfam PF13419 Haloacid dehalogenase-like hydrolase 57 183 1.2E-10 T 29-03-2018 IPR023214 HAD-like domain MC49_RS08190 413e252c9e65a8c46d045af7329f2078 395 SUPERFAMILY SSF51905 119 261 2.48E-19 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS08190 413e252c9e65a8c46d045af7329f2078 395 SUPERFAMILY SSF51905 2 149 2.0E-23 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS08190 413e252c9e65a8c46d045af7329f2078 395 Gene3D G3DSA:3.50.50.60 2 124 8.4E-10 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS08190 413e252c9e65a8c46d045af7329f2078 395 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 141 1.9E-13 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS08190 413e252c9e65a8c46d045af7329f2078 395 Gene3D G3DSA:3.50.50.60 125 261 8.9E-23 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS07560 596e1b33a5ab46d20141cacc394c22fb 432 Gene3D G3DSA:1.20.1250.20 4 223 6.4E-25 T 29-03-2018 MC49_RS07560 596e1b33a5ab46d20141cacc394c22fb 432 SUPERFAMILY SSF103473 6 420 1.01E-57 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS07560 596e1b33a5ab46d20141cacc394c22fb 432 Pfam PF07690 Major Facilitator Superfamily 32 362 9.5E-26 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS07560 596e1b33a5ab46d20141cacc394c22fb 432 Gene3D G3DSA:1.20.1250.20 224 420 2.7E-16 T 29-03-2018 MC49_RS04770 637d111cde988a2b30f28a0153e17383 400 Gene3D G3DSA:2.40.30.10 190 277 1.7E-23 T 29-03-2018 MC49_RS04770 637d111cde988a2b30f28a0153e17383 400 SUPERFAMILY SSF160996 190 338 1.44E-42 T 29-03-2018 MC49_RS04770 637d111cde988a2b30f28a0153e17383 400 SUPERFAMILY SSF51905 337 394 6.49E-59 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS04770 637d111cde988a2b30f28a0153e17383 400 SUPERFAMILY SSF51905 3 188 6.49E-59 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS04770 637d111cde988a2b30f28a0153e17383 400 Gene3D G3DSA:3.50.50.60 4 189 8.3E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS04770 637d111cde988a2b30f28a0153e17383 400 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 7 392 4.5E-126 T 29-03-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like MC49_RS04770 637d111cde988a2b30f28a0153e17383 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 164 7.4E-8 T 29-03-2018 MC49_RS04770 637d111cde988a2b30f28a0153e17383 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 362 369 7.4E-8 T 29-03-2018 MC49_RS04770 637d111cde988a2b30f28a0153e17383 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 7.4E-8 T 29-03-2018 MC49_RS04770 637d111cde988a2b30f28a0153e17383 400 Gene3D G3DSA:1.10.8.260 278 321 5.7E-14 T 29-03-2018 IPR023166 HI0933 insert-like domain MC49_RS04770 637d111cde988a2b30f28a0153e17383 400 Pfam PF03486 HI0933-like protein 5 392 3.9E-152 T 29-03-2018 MC49_RS06690 526a1aa997ebb556a4f016bb85137f02 182 Pfam PF16473 3' exoribonuclease, RNase T-like 1 174 2.3E-46 T 29-03-2018 IPR033390 3'-5' exoribonuclease Rv2179c-like domain MC49_RS06690 526a1aa997ebb556a4f016bb85137f02 182 Gene3D G3DSA:3.30.420.10 1 181 3.2E-12 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MC49_RS06690 526a1aa997ebb556a4f016bb85137f02 182 SUPERFAMILY SSF53098 1 179 5.24E-14 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MC49_RS03455 737fdd0a01636ac46641f71076e02889 323 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 95 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site MC49_RS03455 737fdd0a01636ac46641f71076e02889 323 Gene3D G3DSA:1.10.600.10 1 323 1.2E-101 T 29-03-2018 IPR008949 Isoprenoid synthase domain MC49_RS03455 737fdd0a01636ac46641f71076e02889 323 Pfam PF00348 Polyprenyl synthetase 31 263 2.5E-76 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 MC49_RS03455 737fdd0a01636ac46641f71076e02889 323 SUPERFAMILY SSF48576 5 322 2.24E-100 T 29-03-2018 IPR008949 Isoprenoid synthase domain MC49_RS03455 737fdd0a01636ac46641f71076e02889 323 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 203 215 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site MC49_RS08805 422d17fca0bde219f09a4ace666a4496 159 SUPERFAMILY SSF47741 89 155 7.46E-24 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 MC49_RS08805 422d17fca0bde219f09a4ace666a4496 159 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 44 52 - T 29-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MC49_RS08805 422d17fca0bde219f09a4ace666a4496 159 Gene3D G3DSA:1.10.150.120 80 159 1.2E-25 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 MC49_RS08805 422d17fca0bde219f09a4ace666a4496 159 Gene3D G3DSA:3.10.20.30 4 79 1.0E-20 T 29-03-2018 IPR012675 Beta-grasp domain MC49_RS08805 422d17fca0bde219f09a4ace666a4496 159 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 12 57 5.6E-8 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MC49_RS08805 422d17fca0bde219f09a4ace666a4496 159 SUPERFAMILY SSF54292 8 81 2.75E-19 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MC49_RS08805 422d17fca0bde219f09a4ace666a4496 159 Pfam PF01799 [2Fe-2S] binding domain 78 152 4.4E-23 T 29-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 MC49_RS01185 a95b89264cc595736a114856be63617f 256 Pfam PF10074 Uncharacterized conserved protein (DUF2285) 127 249 2.4E-32 T 29-03-2018 IPR018754 Protein of unknown function DUF2285 MC49_RS04365 2a36e6ff5f6e402f2f10af2fbd9ada0b 444 Pfam PF00672 HAMP domain 180 227 2.7E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MC49_RS04365 2a36e6ff5f6e402f2f10af2fbd9ada0b 444 SMART SM00387 332 440 7.6E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS04365 2a36e6ff5f6e402f2f10af2fbd9ada0b 444 SMART SM00388 233 293 1.0E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS04365 2a36e6ff5f6e402f2f10af2fbd9ada0b 444 Gene3D G3DSA:3.30.565.10 294 444 7.5E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS04365 2a36e6ff5f6e402f2f10af2fbd9ada0b 444 Gene3D G3DSA:1.10.287.130 223 289 1.9E-12 T 29-03-2018 MC49_RS04365 2a36e6ff5f6e402f2f10af2fbd9ada0b 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 418 5.8E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS04365 2a36e6ff5f6e402f2f10af2fbd9ada0b 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 395 5.8E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS04365 2a36e6ff5f6e402f2f10af2fbd9ada0b 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 367 381 5.8E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MC49_RS04365 2a36e6ff5f6e402f2f10af2fbd9ada0b 444 SUPERFAMILY SSF47384 225 289 5.89E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS04365 2a36e6ff5f6e402f2f10af2fbd9ada0b 444 SMART SM00304 180 232 6.6E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 MC49_RS04365 2a36e6ff5f6e402f2f10af2fbd9ada0b 444 SUPERFAMILY SSF55874 292 439 2.62E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS04365 2a36e6ff5f6e402f2f10af2fbd9ada0b 444 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 333 439 5.7E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS04365 2a36e6ff5f6e402f2f10af2fbd9ada0b 444 Pfam PF00512 His Kinase A (phospho-acceptor) domain 236 287 9.4E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MC49_RS03180 bcd3eac34799fed52b2dc7de6f984d00 423 Pfam PF13356 Arm DNA-binding domain 3 87 6.4E-20 T 29-03-2018 IPR025166 Integrase, DNA-binding domain MC49_RS03180 bcd3eac34799fed52b2dc7de6f984d00 423 Gene3D G3DSA:1.10.443.10 205 394 6.6E-21 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MC49_RS03180 bcd3eac34799fed52b2dc7de6f984d00 423 Pfam PF00589 Phage integrase family 225 383 3.3E-19 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MC49_RS03180 bcd3eac34799fed52b2dc7de6f984d00 423 Gene3D G3DSA:1.10.150.130 93 204 2.0E-13 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal MC49_RS03180 bcd3eac34799fed52b2dc7de6f984d00 423 SUPERFAMILY SSF56349 97 388 2.94E-48 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MC49_RS07740 5f9031b15e91346d321f6658d9424a6f 192 Pfam PF05728 Uncharacterised protein family (UPF0227) 4 188 6.7E-60 T 29-03-2018 IPR008886 Uncharacterised protein family UPF0227/Esterase YqiA MC49_RS07740 5f9031b15e91346d321f6658d9424a6f 192 Gene3D G3DSA:3.40.50.1820 2 189 1.5E-18 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS07740 5f9031b15e91346d321f6658d9424a6f 192 SUPERFAMILY SSF53474 3 188 4.25E-20 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS15940 968bac3df811a91c3a43aa9d31848978 257 SUPERFAMILY SSF52540 22 226 1.11E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS15940 968bac3df811a91c3a43aa9d31848978 257 SMART SM00382 26 228 2.0E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS15940 968bac3df811a91c3a43aa9d31848978 257 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS15940 968bac3df811a91c3a43aa9d31848978 257 Gene3D G3DSA:3.40.50.300 21 257 6.1E-36 T 29-03-2018 MC49_RS15940 968bac3df811a91c3a43aa9d31848978 257 Pfam PF00005 ABC transporter 22 163 1.8E-20 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS10160 3a40699e5c3656fdc960cfb767d590cc 241 Gene3D G3DSA:3.40.50.300 1 239 2.8E-72 T 29-03-2018 MC49_RS10160 3a40699e5c3656fdc960cfb767d590cc 241 Pfam PF00005 ABC transporter 17 165 6.4E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS10160 3a40699e5c3656fdc960cfb767d590cc 241 PIRSF PIRSF039085 1 241 2.7E-105 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MC49_RS10160 3a40699e5c3656fdc960cfb767d590cc 241 SUPERFAMILY SSF52540 1 235 1.36E-77 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS10160 3a40699e5c3656fdc960cfb767d590cc 241 SMART SM00382 26 213 2.5E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS10160 3a40699e5c3656fdc960cfb767d590cc 241 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS15320 de855bc5a3153b3137796006e2620a99 282 Pfam PF00005 ABC transporter 22 177 4.3E-22 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS15320 de855bc5a3153b3137796006e2620a99 282 SMART SM00382 29 226 8.2E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS15320 de855bc5a3153b3137796006e2620a99 282 Gene3D G3DSA:3.40.50.300 2 278 6.1E-55 T 29-03-2018 MC49_RS15320 de855bc5a3153b3137796006e2620a99 282 SUPERFAMILY SSF52540 3 239 4.77E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS00370 2bcf88e9509c44aedde77e2d5f758941 245 Pfam PF03837 RecT family 24 169 5.4E-22 T 29-03-2018 IPR018330 RecT family GO:0003677|GO:0006259 MC49_RS00370 2bcf88e9509c44aedde77e2d5f758941 245 TIGRFAM TIGR01913 bet_lambda: phage recombination protein Bet 20 164 2.9E-32 T 29-03-2018 IPR010183 Bacteriophage lambda, Bet MC49_RS01215 0cbf3692b46d646738d88c365bbf3937 172 Pfam PF13527 Acetyltransferase (GNAT) domain 5 133 2.1E-13 T 29-03-2018 MC49_RS01215 0cbf3692b46d646738d88c365bbf3937 172 Gene3D G3DSA:3.40.630.30 91 125 0.0012 T 29-03-2018 MC49_RS01215 0cbf3692b46d646738d88c365bbf3937 172 SUPERFAMILY SSF55729 4 152 1.8E-28 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS01215 0cbf3692b46d646738d88c365bbf3937 172 Gene3D G3DSA:3.40.630.30 1 90 2.1E-16 T 29-03-2018 MC49_RS17255 a8ef28c2c1a298ab4d4e6ceda26f0fa6 239 SUPERFAMILY SSF48317 9 217 1.96E-16 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MC49_RS17255 a8ef28c2c1a298ab4d4e6ceda26f0fa6 239 Pfam PF01569 PAP2 superfamily 117 200 7.8E-8 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MC49_RS17255 a8ef28c2c1a298ab4d4e6ceda26f0fa6 239 Gene3D G3DSA:1.20.144.10 18 218 2.2E-8 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MC49_RS17255 a8ef28c2c1a298ab4d4e6ceda26f0fa6 239 SMART SM00014 92 210 1.3E-6 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MC49_RS09440 9ca8c8ae7deca584496fe12f242983cc 1480 Pfam PF12256 Insecticide toxin TcdB middle/N-terminal region 654 826 7.6E-28 T 29-03-2018 IPR022045 Insecticide toxin TcdB middle/N-terminal MC49_RS09440 9ca8c8ae7deca584496fe12f242983cc 1480 Pfam PF03534 Salmonella virulence plasmid 65kDa B protein 32 322 5.6E-90 T 29-03-2018 IPR003284 Salmonella virulence plasmid 65kDa B protein GO:0005737 MC49_RS09440 9ca8c8ae7deca584496fe12f242983cc 1480 PRINTS PR01341 Salmonella virulence plasmid 65kDa B protein signature 88 104 4.5E-30 T 29-03-2018 IPR003284 Salmonella virulence plasmid 65kDa B protein GO:0005737 MC49_RS09440 9ca8c8ae7deca584496fe12f242983cc 1480 PRINTS PR01341 Salmonella virulence plasmid 65kDa B protein signature 128 146 4.5E-30 T 29-03-2018 IPR003284 Salmonella virulence plasmid 65kDa B protein GO:0005737 MC49_RS09440 9ca8c8ae7deca584496fe12f242983cc 1480 PRINTS PR01341 Salmonella virulence plasmid 65kDa B protein signature 195 213 4.5E-30 T 29-03-2018 IPR003284 Salmonella virulence plasmid 65kDa B protein GO:0005737 MC49_RS09440 9ca8c8ae7deca584496fe12f242983cc 1480 PRINTS PR01341 Salmonella virulence plasmid 65kDa B protein signature 29 50 4.5E-30 T 29-03-2018 IPR003284 Salmonella virulence plasmid 65kDa B protein GO:0005737 MC49_RS09440 9ca8c8ae7deca584496fe12f242983cc 1480 PRINTS PR01341 Salmonella virulence plasmid 65kDa B protein signature 304 322 4.5E-30 T 29-03-2018 IPR003284 Salmonella virulence plasmid 65kDa B protein GO:0005737 MC49_RS09440 9ca8c8ae7deca584496fe12f242983cc 1480 PRINTS PR01341 Salmonella virulence plasmid 65kDa B protein signature 269 288 4.5E-30 T 29-03-2018 IPR003284 Salmonella virulence plasmid 65kDa B protein GO:0005737 MC49_RS09440 9ca8c8ae7deca584496fe12f242983cc 1480 SUPERFAMILY SSF69318 421 695 2.22E-17 T 29-03-2018 MC49_RS09440 9ca8c8ae7deca584496fe12f242983cc 1480 Gene3D G3DSA:2.130.10.130 584 694 1.3E-5 T 29-03-2018 MC49_RS09440 9ca8c8ae7deca584496fe12f242983cc 1480 Gene3D G3DSA:2.130.10.130 426 583 1.6E-6 T 29-03-2018 MC49_RS09440 9ca8c8ae7deca584496fe12f242983cc 1480 Pfam PF12255 Insecticide toxin TcdB middle/C-terminal region 876 1016 4.3E-46 T 29-03-2018 IPR022044 Insecticide toxin TcdB middle/C-terminal MC49_RS18060 9e9fbf1625772f3b7b1d28e27a262562 190 Gene3D G3DSA:1.10.260.40 2 80 3.4E-15 T 29-03-2018 MC49_RS18060 9e9fbf1625772f3b7b1d28e27a262562 190 SMART SM00530 11 66 9.5E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS18060 9e9fbf1625772f3b7b1d28e27a262562 190 Pfam PF07883 Cupin domain 114 177 4.5E-10 T 29-03-2018 IPR013096 Cupin 2, conserved barrel MC49_RS18060 9e9fbf1625772f3b7b1d28e27a262562 190 Pfam PF01381 Helix-turn-helix 13 64 4.4E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS18060 9e9fbf1625772f3b7b1d28e27a262562 190 SUPERFAMILY SSF47413 3 71 1.8E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS18060 9e9fbf1625772f3b7b1d28e27a262562 190 Gene3D G3DSA:2.60.120.10 93 190 5.7E-14 T 29-03-2018 IPR014710 RmlC-like jelly roll fold MC49_RS18060 9e9fbf1625772f3b7b1d28e27a262562 190 SUPERFAMILY SSF51182 51 187 1.73E-23 T 29-03-2018 IPR011051 RmlC-like cupin domain MC49_RS02180 93e6da6de3e8fc7b1ec5247234bce3a7 421 Gene3D G3DSA:3.30.460.10 17 201 4.4E-20 T 29-03-2018 MC49_RS02180 93e6da6de3e8fc7b1ec5247234bce3a7 421 SMART SM00954 62 220 4.3E-8 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 MC49_RS02180 93e6da6de3e8fc7b1ec5247234bce3a7 421 SUPERFAMILY SSF81301 163 248 4.09E-23 T 29-03-2018 MC49_RS02180 93e6da6de3e8fc7b1ec5247234bce3a7 421 SUPERFAMILY SSF81301 24 135 4.09E-23 T 29-03-2018 MC49_RS02180 93e6da6de3e8fc7b1ec5247234bce3a7 421 Pfam PF04607 Region found in RelA / SpoT proteins 63 216 5.4E-18 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 MC49_RS15670 ce534117405d48b1e1f4b6c9db2cc4a6 155 Pfam PF05433 Glycine zipper 2TM domain 63 103 1.4E-7 T 29-03-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 MC49_RS17210 919c286248e3f39ea914162a7d0d1c4d 288 SUPERFAMILY SSF53850 87 287 8.15E-41 T 29-03-2018 MC49_RS17210 919c286248e3f39ea914162a7d0d1c4d 288 Gene3D G3DSA:3.40.190.10 86 173 1.0E-21 T 29-03-2018 MC49_RS17210 919c286248e3f39ea914162a7d0d1c4d 288 Gene3D G3DSA:3.40.190.10 174 261 7.1E-19 T 29-03-2018 MC49_RS17210 919c286248e3f39ea914162a7d0d1c4d 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.9E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS17210 919c286248e3f39ea914162a7d0d1c4d 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.9E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS17210 919c286248e3f39ea914162a7d0d1c4d 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.9E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS17210 919c286248e3f39ea914162a7d0d1c4d 288 SUPERFAMILY SSF46785 1 108 1.63E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS17210 919c286248e3f39ea914162a7d0d1c4d 288 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 3.5E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS17210 919c286248e3f39ea914162a7d0d1c4d 288 Pfam PF03466 LysR substrate binding domain 87 288 2.4E-43 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS17210 919c286248e3f39ea914162a7d0d1c4d 288 Gene3D G3DSA:1.10.10.10 1 84 1.2E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS14800 3ffa41cb935028b70e9cca3d357387b6 280 SUPERFAMILY SSF54506 5 277 7.37E-66 T 29-03-2018 MC49_RS14800 3ffa41cb935028b70e9cca3d357387b6 280 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 5 277 2.4E-51 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 MC49_RS14800 3ffa41cb935028b70e9cca3d357387b6 280 Pfam PF02567 Phenazine biosynthesis-like protein 11 275 2.6E-47 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 MC49_RS14800 3ffa41cb935028b70e9cca3d357387b6 280 Gene3D G3DSA:3.10.310.10 135 267 8.4E-29 T 29-03-2018 MC49_RS14800 3ffa41cb935028b70e9cca3d357387b6 280 PIRSF PIRSF016184 3 279 8.2E-64 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 MC49_RS14800 3ffa41cb935028b70e9cca3d357387b6 280 Gene3D G3DSA:3.10.310.10 2 134 1.1E-31 T 29-03-2018 MC49_RS07070 b36831e560167505d0b7ad0903155aa3 202 SUPERFAMILY SSF75620 2 196 1.28E-46 T 29-03-2018 MC49_RS07070 b36831e560167505d0b7ad0903155aa3 202 TIGRFAM TIGR03072 release_prfH: putative peptide chain release factor H 1 197 5.0E-84 T 29-03-2018 IPR017509 Putative peptide chain release factor H MC49_RS07070 b36831e560167505d0b7ad0903155aa3 202 Pfam PF00472 RF-1 domain 101 188 1.6E-22 T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MC49_RS07070 b36831e560167505d0b7ad0903155aa3 202 Gene3D G3DSA:3.30.160.20 100 192 3.7E-23 T 29-03-2018 MC49_RS17140 8240b6721923edc7b54fb78ddec39c7c 1051 Pfam PF10150 Ribonuclease E/G family 118 388 2.2E-91 T 29-03-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 MC49_RS17140 8240b6721923edc7b54fb78ddec39c7c 1051 Gene3D G3DSA:2.40.50.140 30 121 6.8E-32 T 29-03-2018 MC49_RS17140 8240b6721923edc7b54fb78ddec39c7c 1051 Pfam PF00575 S1 RNA binding domain 33 115 1.3E-15 T 29-03-2018 IPR003029 S1 domain GO:0003676 MC49_RS17140 8240b6721923edc7b54fb78ddec39c7c 1051 Hamap MF_00970 Ribonuclease E [rne]. 1 1039 36.578 T 29-03-2018 IPR028878 Ribonuclease E GO:0006396|GO:0008995 MC49_RS17140 8240b6721923edc7b54fb78ddec39c7c 1051 SMART SM00316 34 116 2.9E-12 T 29-03-2018 IPR022967 RNA-binding domain, S1 MC49_RS17140 8240b6721923edc7b54fb78ddec39c7c 1051 SUPERFAMILY SSF50249 37 121 1.41E-20 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS17140 8240b6721923edc7b54fb78ddec39c7c 1051 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 10 422 1.2E-168 T 29-03-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 MC49_RS12230 dd7d369a9cf4b7f3b15c3a49b6cdf195 137 SUPERFAMILY SSF101756 48 132 8.5E-18 T 29-03-2018 IPR005220 Bacterial OB-fold MC49_RS12230 dd7d369a9cf4b7f3b15c3a49b6cdf195 137 Pfam PF04076 Bacterial OB fold (BOF) protein 48 126 1.1E-12 T 29-03-2018 IPR005220 Bacterial OB-fold MC49_RS12230 dd7d369a9cf4b7f3b15c3a49b6cdf195 137 Gene3D G3DSA:2.40.50.200 28 135 3.2E-15 T 29-03-2018 MC49_RS13370 e5757be958b83e99f562720336e21dbb 495 Pfam PF11863 Protein of unknown function (DUF3383) 6 494 3.0E-125 T 29-03-2018 IPR021808 Protein of unknown function DUF3383 MC49_RS05125 fde7496533edce7c2231a28e7164f4e7 147 SUPERFAMILY SSF52218 1 147 1.56E-40 T 29-03-2018 IPR029039 Flavoprotein-like domain MC49_RS05125 fde7496533edce7c2231a28e7164f4e7 147 Gene3D G3DSA:3.40.50.360 1 147 1.6E-34 T 29-03-2018 IPR029039 Flavoprotein-like domain MC49_RS05125 fde7496533edce7c2231a28e7164f4e7 147 Pfam PF00258 Flavodoxin 7 139 1.8E-27 T 29-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 MC49_RS05125 fde7496533edce7c2231a28e7164f4e7 147 PRINTS PR00369 Flavodoxin signature 107 126 4.4E-9 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MC49_RS05125 fde7496533edce7c2231a28e7164f4e7 147 PRINTS PR00369 Flavodoxin signature 52 63 4.4E-9 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MC49_RS05125 fde7496533edce7c2231a28e7164f4e7 147 PRINTS PR00369 Flavodoxin signature 5 18 4.4E-9 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MC49_RS05125 fde7496533edce7c2231a28e7164f4e7 147 PRINTS PR00369 Flavodoxin signature 83 93 4.4E-9 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MC49_RS08750 7c348a76c7902c569c48611cc6b677c3 183 Hamap MF_00299 Probable RNA 2'-phosphotransferase [kptA]. 3 177 32.998 T 29-03-2018 IPR022928 RNA 2'-phosphotransferase KptA, putative GO:0016773 MC49_RS08750 7c348a76c7902c569c48611cc6b677c3 183 Pfam PF01885 RNA 2'-phosphotransferase, Tpt1 / KptA family 5 170 1.2E-38 T 29-03-2018 IPR002745 Phosphotransferase KptA/Tpt1 GO:0006388|GO:0016772 MC49_RS08750 7c348a76c7902c569c48611cc6b677c3 183 SUPERFAMILY SSF56399 6 179 5.47E-56 T 29-03-2018 MC49_RS08365 89ece1ce5a7321b83d01bffceb926fc8 255 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 4 252 3.2E-58 T 29-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 MC49_RS08365 89ece1ce5a7321b83d01bffceb926fc8 255 Pfam PF02654 Cobalamin-5-phosphate synthase 10 250 1.9E-54 T 29-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 MC49_RS08365 89ece1ce5a7321b83d01bffceb926fc8 255 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 255 43.732 T 29-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 MC49_RS15530 301758317f0071028f4ddb5887da4941 199 Pfam PF13599 Pentapeptide repeats (9 copies) 115 185 6.0E-10 T 29-03-2018 IPR001646 Pentapeptide repeat MC49_RS15530 301758317f0071028f4ddb5887da4941 199 Pfam PF13599 Pentapeptide repeats (9 copies) 30 110 1.0E-10 T 29-03-2018 IPR001646 Pentapeptide repeat MC49_RS15530 301758317f0071028f4ddb5887da4941 199 Gene3D G3DSA:2.160.20.80 3 199 1.6E-33 T 29-03-2018 MC49_RS15530 301758317f0071028f4ddb5887da4941 199 SUPERFAMILY SSF141571 13 197 1.86E-40 T 29-03-2018 MC49_RS11325 00a3f0337fd533ca54b3f88ed6f1c792 738 Pfam PF12805 FUSC-like inner membrane protein yccS 69 348 2.2E-103 T 29-03-2018 IPR032692 Integral membrane protein YccS, N-terminal MC49_RS11325 00a3f0337fd533ca54b3f88ed6f1c792 738 Pfam PF13515 Fusaric acid resistance protein-like 410 529 6.5E-24 T 29-03-2018 MC49_RS11325 00a3f0337fd533ca54b3f88ed6f1c792 738 TIGRFAM TIGR01666 YCCS: TIGR01666 family membrane protein 10 710 5.9E-285 T 29-03-2018 IPR010019 Integral membrane protein, YccS MC49_RS11325 00a3f0337fd533ca54b3f88ed6f1c792 738 TIGRFAM TIGR01667 YCCS_YHJK: integral membrane protein, YccS/YhfK family 10 709 4.9E-254 T 29-03-2018 IPR010020 Integral membrane protein, YccS/YhfK MC49_RS04440 9db1f4f6ed3868a316d05312ce9ef313 476 Pfam PF10077 Uncharacterized protein conserved in bacteria (DUF2314) 393 471 1.7E-8 T 29-03-2018 IPR018756 Domain of unknown function DUF2314 MC49_RS04440 9db1f4f6ed3868a316d05312ce9ef313 476 Pfam PF13218 Protein of unknown function (DUF4026) 16 336 1.4E-178 T 29-03-2018 IPR025102 Protein of unknown function DUF4026 MC49_RS18425 17a818b56e04ab7aa9ab2d1f7e0f51b3 327 Pfam PF01571 Aminomethyltransferase folate-binding domain 24 134 6.0E-10 T 29-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal MC49_RS18425 17a818b56e04ab7aa9ab2d1f7e0f51b3 327 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 185 249 2.1E-22 T 29-03-2018 IPR017703 YgfZ/GcvT conserved site MC49_RS18425 17a818b56e04ab7aa9ab2d1f7e0f51b3 327 SUPERFAMILY SSF103025 18 240 7.06E-60 T 29-03-2018 MC49_RS18425 17a818b56e04ab7aa9ab2d1f7e0f51b3 327 PIRSF PIRSF006487 180 322 5.3 T 29-03-2018 MC49_RS18425 17a818b56e04ab7aa9ab2d1f7e0f51b3 327 PIRSF PIRSF006487 19 148 3.9E-10 T 29-03-2018 MC49_RS18425 17a818b56e04ab7aa9ab2d1f7e0f51b3 327 Gene3D G3DSA:3.30.70.1400 26 238 5.7E-25 T 29-03-2018 MC49_RS18425 17a818b56e04ab7aa9ab2d1f7e0f51b3 327 Hamap MF_01175 tRNA-modifying protein YgfZ [ygfZ]. 1 320 43.172 T 29-03-2018 IPR023758 tRNA-modifying protein YgfZ GO:0005542|GO:0009451 MC49_RS18425 17a818b56e04ab7aa9ab2d1f7e0f51b3 327 SUPERFAMILY SSF101790 242 323 1.5E-23 T 29-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain MC49_RS03250 f41dfb42def9f9158e935e1e8cb074c9 154 SUPERFAMILY SSF54893 2 100 1.19E-34 T 29-03-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal MC49_RS03250 f41dfb42def9f9158e935e1e8cb074c9 154 TIGRFAM TIGR00240 ATCase_reg: aspartate carbamoyltransferase, regulatory subunit 5 151 7.8E-60 T 29-03-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 MC49_RS03250 f41dfb42def9f9158e935e1e8cb074c9 154 ProDom PD006194 REGULATORY ASPARTATE CARBAMOYLTRANSFERASE CHAIN METAL-BINDING ZINC PYRIMIDINE BIOSYNTHESIS SUBUNIT TRANSFERASE 9 99 2.0E-35 T 29-03-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal MC49_RS03250 f41dfb42def9f9158e935e1e8cb074c9 154 Gene3D G3DSA:3.30.70.140 5 97 5.4E-33 T 29-03-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal MC49_RS03250 f41dfb42def9f9158e935e1e8cb074c9 154 SUPERFAMILY SSF57825 101 151 3.27E-14 T 29-03-2018 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal MC49_RS03250 f41dfb42def9f9158e935e1e8cb074c9 154 Gene3D G3DSA:2.30.30.20 102 150 1.0E-16 T 29-03-2018 MC49_RS03250 f41dfb42def9f9158e935e1e8cb074c9 154 Hamap MF_00002 Aspartate carbamoyltransferase regulatory chain [pyrI]. 4 152 32.124 T 29-03-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 MC49_RS03250 f41dfb42def9f9158e935e1e8cb074c9 154 Pfam PF01948 Aspartate carbamoyltransferase regulatory chain, allosteric domain 8 96 6.1E-30 T 29-03-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal MC49_RS03250 f41dfb42def9f9158e935e1e8cb074c9 154 Pfam PF02748 Aspartate carbamoyltransferase regulatory chain, metal binding domain 102 150 2.7E-17 T 29-03-2018 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal MC49_RS00250 f69e4dfa88bc95f2e08d0d6e2dbbd0fa 160 Gene3D G3DSA:3.90.1720.10 2 138 6.6E-9 T 29-03-2018 MC49_RS00250 f69e4dfa88bc95f2e08d0d6e2dbbd0fa 160 Pfam PF05257 CHAP domain 45 117 9.2E-6 T 29-03-2018 IPR007921 CHAP domain MC49_RS00250 f69e4dfa88bc95f2e08d0d6e2dbbd0fa 160 TIGRFAM TIGR02594 TIGR02594: TIGR02594 family protein 6 137 7.4E-38 T 29-03-2018 IPR013423 Conserved hypothetical protein CHP02594 MC49_RS16405 e1b78120126bd6e4016a8eb6ae48fc8c 484 TIGRFAM TIGR00835 agcS: amino acid carrier protein 13 442 1.0E-158 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MC49_RS16405 e1b78120126bd6e4016a8eb6ae48fc8c 484 PRINTS PR00175 Sodium/alanine symporter signature 411 431 9.1E-56 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MC49_RS16405 e1b78120126bd6e4016a8eb6ae48fc8c 484 PRINTS PR00175 Sodium/alanine symporter signature 87 109 9.1E-56 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MC49_RS16405 e1b78120126bd6e4016a8eb6ae48fc8c 484 PRINTS PR00175 Sodium/alanine symporter signature 206 225 9.1E-56 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MC49_RS16405 e1b78120126bd6e4016a8eb6ae48fc8c 484 PRINTS PR00175 Sodium/alanine symporter signature 350 372 9.1E-56 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MC49_RS16405 e1b78120126bd6e4016a8eb6ae48fc8c 484 PRINTS PR00175 Sodium/alanine symporter signature 178 196 9.1E-56 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MC49_RS16405 e1b78120126bd6e4016a8eb6ae48fc8c 484 PRINTS PR00175 Sodium/alanine symporter signature 303 321 9.1E-56 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MC49_RS16405 e1b78120126bd6e4016a8eb6ae48fc8c 484 Pfam PF01235 Sodium:alanine symporter family 47 453 1.5E-160 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MC49_RS16405 e1b78120126bd6e4016a8eb6ae48fc8c 484 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 87 102 - T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MC49_RS17450 f3c0f2edaff1f58562e8c95fcddcabe5 338 Pfam PF09615 CRISPR-associated protein (Cas_Csy3) 7 335 3.3E-106 T 29-03-2018 IPR013399 CRISPR-associated protein Csy3 MC49_RS17450 f3c0f2edaff1f58562e8c95fcddcabe5 338 TIGRFAM TIGR02566 cas_Csy3: CRISPR type I-F/YPEST-associated protein Csy3 7 337 4.1E-95 T 29-03-2018 IPR013399 CRISPR-associated protein Csy3 MC49_RS18165 f7d8962fe99a9df122e1b795792fc9d1 384 Pfam PF00288 GHMP kinases N terminal domain 116 182 8.6E-12 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 MC49_RS18165 f7d8962fe99a9df122e1b795792fc9d1 384 Hamap MF_00246 Galactokinase [galK]. 26 382 42.811 T 29-03-2018 IPR022963 Galactokinase, bacterial GO:0004335|GO:0006012 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MC49_RS18165 f7d8962fe99a9df122e1b795792fc9d1 384 Pfam PF10509 Galactokinase galactose-binding signature 11 58 2.6E-24 T 29-03-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MC49_RS18165 f7d8962fe99a9df122e1b795792fc9d1 384 Gene3D G3DSA:3.30.230.10 3 207 2.5E-61 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MC49_RS18165 f7d8962fe99a9df122e1b795792fc9d1 384 PIRSF PIRSF000530 1 384 1.4E-120 T 29-03-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MC49_RS18165 f7d8962fe99a9df122e1b795792fc9d1 384 SUPERFAMILY SSF54211 3 204 2.73E-64 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MC49_RS18165 f7d8962fe99a9df122e1b795792fc9d1 384 TIGRFAM TIGR00131 gal_kin: galactokinase 7 382 3.7E-144 T 29-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MC49_RS18165 f7d8962fe99a9df122e1b795792fc9d1 384 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 122 133 - T 29-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 MC49_RS18165 f7d8962fe99a9df122e1b795792fc9d1 384 PRINTS PR00473 Galactokinase signature 113 131 1.9E-30 T 29-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MC49_RS18165 f7d8962fe99a9df122e1b795792fc9d1 384 PRINTS PR00473 Galactokinase signature 28 46 1.9E-30 T 29-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MC49_RS18165 f7d8962fe99a9df122e1b795792fc9d1 384 PRINTS PR00473 Galactokinase signature 93 104 1.9E-30 T 29-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MC49_RS18165 f7d8962fe99a9df122e1b795792fc9d1 384 PRINTS PR00473 Galactokinase signature 264 278 1.9E-30 T 29-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MC49_RS18165 f7d8962fe99a9df122e1b795792fc9d1 384 Gene3D G3DSA:3.30.70.890 208 382 7.8E-53 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain MC49_RS18165 f7d8962fe99a9df122e1b795792fc9d1 384 PRINTS PR00959 Mevalonate kinase family signature 26 50 4.9E-45 T 29-03-2018 MC49_RS18165 f7d8962fe99a9df122e1b795792fc9d1 384 PRINTS PR00959 Mevalonate kinase family signature 120 142 4.9E-45 T 29-03-2018 MC49_RS18165 f7d8962fe99a9df122e1b795792fc9d1 384 PRINTS PR00959 Mevalonate kinase family signature 329 346 4.9E-45 T 29-03-2018 MC49_RS18165 f7d8962fe99a9df122e1b795792fc9d1 384 PRINTS PR00959 Mevalonate kinase family signature 163 182 4.9E-45 T 29-03-2018 MC49_RS18165 f7d8962fe99a9df122e1b795792fc9d1 384 ProSitePatterns PS00106 Galactokinase signature. 28 39 - T 29-03-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MC49_RS18165 f7d8962fe99a9df122e1b795792fc9d1 384 SUPERFAMILY SSF55060 207 383 3.68E-51 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain MC49_RS18165 f7d8962fe99a9df122e1b795792fc9d1 384 Pfam PF08544 GHMP kinases C terminal 280 361 3.9E-11 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain MC49_RS14345 621b66fc8bcb4534d00f1852e76f813a 63 ProDom PD052969 LIPOPROTEIN PRECURSOR SIGNAL YNBE MEMBRANE OUTER POSSIBLE SIMILAR ECS2004 SO2063 17 63 1.0E-15 T 29-03-2018 MC49_RS14345 621b66fc8bcb4534d00f1852e76f813a 63 Pfam PF13617 YnbE-like lipoprotein 9 60 2.8E-24 T 29-03-2018 IPR025985 YnbE-like lipoprotein MC49_RS02935 2ab78fe32e29aa1784311aa804f7a38e 244 Gene3D G3DSA:1.10.3480.10 24 206 8.4E-28 T 29-03-2018 IPR020945 DMSO/Nitrate reductase chaperone MC49_RS02935 2ab78fe32e29aa1784311aa804f7a38e 244 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 9 161 8.6E-43 T 29-03-2018 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 MC49_RS02935 2ab78fe32e29aa1784311aa804f7a38e 244 Pfam PF02613 Nitrate reductase delta subunit 41 148 5.0E-10 T 29-03-2018 IPR020945 DMSO/Nitrate reductase chaperone MC49_RS02935 2ab78fe32e29aa1784311aa804f7a38e 244 SUPERFAMILY SSF89155 3 163 2.22E-31 T 29-03-2018 IPR020945 DMSO/Nitrate reductase chaperone MC49_RS16455 0550b7305d1a063d1ba4bd0784845409 556 Gene3D G3DSA:3.40.50.970 1 204 1.7E-52 T 29-03-2018 MC49_RS16455 0550b7305d1a063d1ba4bd0784845409 556 Gene3D G3DSA:3.40.50.970 355 556 1.3E-26 T 29-03-2018 MC49_RS16455 0550b7305d1a063d1ba4bd0784845409 556 PIRSF PIRSF004983 1 556 3.3E-171 T 29-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 MC49_RS16455 0550b7305d1a063d1ba4bd0784845409 556 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 10 431 3.3E-134 T 29-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 MC49_RS16455 0550b7305d1a063d1ba4bd0784845409 556 SUPERFAMILY SSF52518 7 175 3.68E-29 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MC49_RS16455 0550b7305d1a063d1ba4bd0784845409 556 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 9 129 1.4E-24 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MC49_RS16455 0550b7305d1a063d1ba4bd0784845409 556 Gene3D G3DSA:3.40.50.1220 217 354 3.1E-19 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MC49_RS16455 0550b7305d1a063d1ba4bd0784845409 556 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 4 554 31.691 T 29-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 MC49_RS16455 0550b7305d1a063d1ba4bd0784845409 556 SUPERFAMILY SSF52467 219 358 5.09E-8 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MC49_RS16455 0550b7305d1a063d1ba4bd0784845409 556 Pfam PF16582 Middle domain of thiamine pyrophosphate 184 388 4.0E-85 T 29-03-2018 IPR032264 Menaquinone biosynthesis protein MenD, middle domain KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 MC49_RS16455 0550b7305d1a063d1ba4bd0784845409 556 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 421 536 6.1E-8 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MC49_RS16455 0550b7305d1a063d1ba4bd0784845409 556 SUPERFAMILY SSF52518 363 549 3.21E-31 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold MC49_RS12665 c33c71ea1baaf0db4ee504b8870c13ab 167 Pfam PF14302 Domain of unknown function (DUF4377) 34 108 3.5E-29 T 29-03-2018 IPR025485 Domain of unknown function DUF4377 MC49_RS12665 c33c71ea1baaf0db4ee504b8870c13ab 167 Pfam PF03891 Domain of unknown function (DUF333) 119 164 4.0E-21 T 29-03-2018 IPR005590 Protein of unknown function DUF333 MC49_RS00745 4411d15db27069fcb65d9861746a1a77 426 SMART SM00382 114 317 5.9E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS00745 4411d15db27069fcb65d9861746a1a77 426 Pfam PF07724 AAA domain (Cdc48 subfamily) 115 313 3.6E-48 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MC49_RS00745 4411d15db27069fcb65d9861746a1a77 426 Gene3D G3DSA:3.40.50.300 58 318 7.8E-69 T 29-03-2018 MC49_RS00745 4411d15db27069fcb65d9861746a1a77 426 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 320 398 9.6E-16 T 29-03-2018 IPR019489 Clp ATPase, C-terminal MC49_RS00745 4411d15db27069fcb65d9861746a1a77 426 SMART SM00994 12 51 1.3E-24 T 29-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 MC49_RS00745 4411d15db27069fcb65d9861746a1a77 426 Pfam PF06689 ClpX C4-type zinc finger 13 50 1.7E-20 T 29-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 MC49_RS00745 4411d15db27069fcb65d9861746a1a77 426 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 5 415 3.3E-212 T 29-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 MC49_RS00745 4411d15db27069fcb65d9861746a1a77 426 SUPERFAMILY SSF52540 64 405 1.05E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS00745 4411d15db27069fcb65d9861746a1a77 426 SUPERFAMILY SSF57716 13 48 4.13E-12 T 29-03-2018 MC49_RS00745 4411d15db27069fcb65d9861746a1a77 426 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 4 418 53.698 T 29-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 MC49_RS00745 4411d15db27069fcb65d9861746a1a77 426 Gene3D G3DSA:1.10.8.60 320 412 1.0E-31 T 29-03-2018 MC49_RS00745 4411d15db27069fcb65d9861746a1a77 426 SMART SM01086 320 406 4.3E-31 T 29-03-2018 IPR019489 Clp ATPase, C-terminal MC49_RS02315 0581e9cf83600f224d8e780c0e2c3b37 269 TIGRFAM TIGR02769 nickel_nikE: nickel import ATP-binding protein NikE 2 264 1.1E-111 T 29-03-2018 IPR014137 Nickel import ATP-binding protein NikE GO:0005886|GO:0015413|GO:0015675|GO:0016151 MC49_RS02315 0581e9cf83600f224d8e780c0e2c3b37 269 Pfam PF00005 ABC transporter 28 179 1.4E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS02315 0581e9cf83600f224d8e780c0e2c3b37 269 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS02315 0581e9cf83600f224d8e780c0e2c3b37 269 Gene3D G3DSA:3.40.50.300 1 268 1.9E-65 T 29-03-2018 MC49_RS02315 0581e9cf83600f224d8e780c0e2c3b37 269 SMART SM00382 37 229 9.6E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS02315 0581e9cf83600f224d8e780c0e2c3b37 269 SUPERFAMILY SSF52540 3 236 1.15E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS12985 20d785797fd355dd74eb6ecf9896d3db 143 Gene3D G3DSA:3.30.70.1290 10 142 2.0E-22 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MC49_RS12985 20d785797fd355dd74eb6ecf9896d3db 143 SUPERFAMILY SSF143422 11 140 2.22E-44 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MC49_RS12985 20d785797fd355dd74eb6ecf9896d3db 143 SMART SM01321 19 139 4.2E-41 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MC49_RS12985 20d785797fd355dd74eb6ecf9896d3db 143 Pfam PF01797 Transposase IS200 like 21 139 9.3E-39 T 29-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MC49_RS09100 65e06971e65a42bc6ab6e51eb2e53434 190 Gene3D G3DSA:1.10.3480.10 1 187 5.7E-39 T 29-03-2018 IPR020945 DMSO/Nitrate reductase chaperone MC49_RS09100 65e06971e65a42bc6ab6e51eb2e53434 190 SUPERFAMILY SSF89155 7 186 4.32E-40 T 29-03-2018 IPR020945 DMSO/Nitrate reductase chaperone MC49_RS09100 65e06971e65a42bc6ab6e51eb2e53434 190 PIRSF PIRSF004690 1 189 4.0E-38 T 29-03-2018 IPR026269 Tat proofreading chaperone DmsD-type MC49_RS09100 65e06971e65a42bc6ab6e51eb2e53434 190 Pfam PF02613 Nitrate reductase delta subunit 51 161 4.7E-22 T 29-03-2018 IPR020945 DMSO/Nitrate reductase chaperone MC49_RS03470 aa8167821359d34379d01ff66f891694 312 Gene3D G3DSA:3.90.110.10 148 312 9.1E-43 T 29-03-2018 MC49_RS03470 aa8167821359d34379d01ff66f891694 312 TIGRFAM TIGR01772 MDH_euk_gproteo: malate dehydrogenase, NAD-dependent 2 312 5.3E-135 T 29-03-2018 IPR010097 Malate dehydrogenase, type 1 GO:0006099|GO:0030060 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|Reactome: R-HSA-70263|Reactome: R-HSA-71403 MC49_RS03470 aa8167821359d34379d01ff66f891694 312 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 1 145 2.8E-45 T 29-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 MC49_RS03470 aa8167821359d34379d01ff66f891694 312 ProSitePatterns PS00068 Malate dehydrogenase active site signature. 146 158 - T 29-03-2018 IPR001252 Malate dehydrogenase, active site GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|Reactome: R-HSA-70263 MC49_RS03470 aa8167821359d34379d01ff66f891694 312 SUPERFAMILY SSF51735 1 145 7.25E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS03470 aa8167821359d34379d01ff66f891694 312 Hamap MF_01516 Malate dehydrogenase [mdh]. 1 311 58.702 T 29-03-2018 IPR023958 Malate dehydrogenase, type 1, bacterial GO:0006099|GO:0030060|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 MC49_RS03470 aa8167821359d34379d01ff66f891694 312 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 147 309 5.4E-50 T 29-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 MC49_RS03470 aa8167821359d34379d01ff66f891694 312 Gene3D G3DSA:3.40.50.720 2 147 3.1E-41 T 29-03-2018 MC49_RS03470 aa8167821359d34379d01ff66f891694 312 SUPERFAMILY SSF56327 146 311 3.73E-42 T 29-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 MC49_RS03470 aa8167821359d34379d01ff66f891694 312 PIRSF PIRSF000102 1 310 9.0E-62 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MC49_RS07315 df5dcf9d2ab18610849c424fc3488a13 425 Pfam PF07670 Nucleoside recognition 99 195 1.2E-8 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 MC49_RS07315 df5dcf9d2ab18610849c424fc3488a13 425 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 201 422 1.3E-76 T 29-03-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 MC49_RS07315 df5dcf9d2ab18610849c424fc3488a13 425 TIGRFAM TIGR00804 nupC: nucleoside transporter, NupC family 4 422 2.5E-151 T 29-03-2018 IPR018270 Concentrative nucleoside transporter, metazoan/bacterial GO:0005337|GO:0016020|GO:1901642 Reactome: R-HSA-83936 MC49_RS07315 df5dcf9d2ab18610849c424fc3488a13 425 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 81 1.5E-22 T 29-03-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 MC49_RS07415 ddae9e731325fb4ec026a82ca0526be1 211 Hamap MF_01389 Urease accessory protein UreG [ureG]. 3 204 44.654 T 29-03-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 MC49_RS07415 ddae9e731325fb4ec026a82ca0526be1 211 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 5 200 3.2E-78 T 29-03-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 MC49_RS07415 ddae9e731325fb4ec026a82ca0526be1 211 SUPERFAMILY SSF52540 2 202 1.05E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS07415 ddae9e731325fb4ec026a82ca0526be1 211 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 7 178 1.4E-30 T 29-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain MC49_RS07415 ddae9e731325fb4ec026a82ca0526be1 211 Gene3D G3DSA:3.40.50.300 3 201 1.3E-18 T 29-03-2018 MC49_RS07415 ddae9e731325fb4ec026a82ca0526be1 211 PIRSF PIRSF005624 1 210 1.6E-46 T 29-03-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 MC49_RS06775 0703f686101b46c27ed4e37343c5bfba 178 Pfam PF05869 DNA N-6-adenine-methyltransferase (Dam) 7 173 9.9E-64 T 29-03-2018 IPR008593 DNA N-6-adenine-methyltransferase GO:0003677|GO:0009007|GO:0032775 MC49_RS06775 0703f686101b46c27ed4e37343c5bfba 178 TIGRFAM TIGR01712 phage_N6A_met: phage N-6-adenine-methyltransferase 6 169 3.6E-63 T 29-03-2018 IPR008593 DNA N-6-adenine-methyltransferase GO:0003677|GO:0009007|GO:0032775 MC49_RS09295 ff3b100d0205adbd84a74927924898ee 195 Pfam PF02342 TerD domain 2 179 6.9E-47 T 29-03-2018 IPR003325 TerD domain GO:0006950 MC49_RS09295 ff3b100d0205adbd84a74927924898ee 195 Gene3D G3DSA:2.60.60.30 17 183 7.4E-48 T 29-03-2018 MC49_RS09395 55b48d1c9f681d669c0555fc2b0de0bc 531 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 6 529 7.9E-127 T 29-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 MC49_RS09395 55b48d1c9f681d669c0555fc2b0de0bc 531 Pfam PF02652 L-lactate permease 9 528 3.9E-134 T 29-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 MC49_RS09015 22f77d7d9ddd616fe3eb2ac6dd37be86 447 SUPERFAMILY SSF56954 4 423 5.1E-66 T 29-03-2018 MC49_RS09015 22f77d7d9ddd616fe3eb2ac6dd37be86 447 Gene3D G3DSA:1.20.1600.10 17 427 7.3E-59 T 29-03-2018 MC49_RS09015 22f77d7d9ddd616fe3eb2ac6dd37be86 447 Pfam PF02321 Outer membrane efflux protein 244 423 2.7E-24 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MC49_RS09015 22f77d7d9ddd616fe3eb2ac6dd37be86 447 Pfam PF02321 Outer membrane efflux protein 25 212 3.6E-18 T 29-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 MC49_RS12780 d53ed9b54b00d6e41337852d822e1b45 194 Gene3D G3DSA:3.40.50.1240 1 193 0.0058 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MC49_RS12780 d53ed9b54b00d6e41337852d822e1b45 194 SUPERFAMILY SSF53254 4 190 5.78E-7 T 29-03-2018 IPR029033 Histidine phosphatase superfamily MC49_RS01775 11c46d22ab9f1b5f8c1155057987e17b 560 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 2 558 34.13 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 MC49_RS01775 11c46d22ab9f1b5f8c1155057987e17b 560 Pfam PF03814 Potassium-transporting ATPase A subunit 12 556 6.2E-232 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 MC49_RS01775 11c46d22ab9f1b5f8c1155057987e17b 560 PIRSF PIRSF001294 1 560 7.3E-227 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 MC49_RS01775 11c46d22ab9f1b5f8c1155057987e17b 560 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 1 557 2.3E-247 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 MC49_RS15825 75cd16cadb01f930dac9c65b96c3bace 141 Gene3D G3DSA:3.10.129.10 1 141 9.6E-27 T 29-03-2018 MC49_RS15825 75cd16cadb01f930dac9c65b96c3bace 141 Pfam PF03061 Thioesterase superfamily 50 127 1.9E-16 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MC49_RS15825 75cd16cadb01f930dac9c65b96c3bace 141 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 19 134 3.1E-42 T 29-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 MC49_RS15825 75cd16cadb01f930dac9c65b96c3bace 141 SUPERFAMILY SSF54637 4 136 2.8E-30 T 29-03-2018 IPR029069 HotDog domain MC49_RS14550 4ce812dd5372258dc3f209ad83949d6f 309 Pfam PF04261 Dyp-type peroxidase family 30 303 3.1E-80 T 29-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 MC49_RS14550 4ce812dd5372258dc3f209ad83949d6f 309 SUPERFAMILY SSF54909 4 307 8.58E-98 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel MC49_RS14550 4ce812dd5372258dc3f209ad83949d6f 309 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 13 303 8.4E-75 T 29-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 MC49_RS16495 1b59460ff0c40ed67c7820982e8ecfd1 178 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 16 158 6.2E-32 T 29-03-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS18045 1299637578d692ec71042e7266f43fea 193 Gene3D G3DSA:3.40.50.1820 3 193 1.9E-19 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS18045 1299637578d692ec71042e7266f43fea 193 SUPERFAMILY SSF53474 4 61 2.34E-17 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS18045 1299637578d692ec71042e7266f43fea 193 SUPERFAMILY SSF53474 118 192 2.34E-17 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS13855 567b739798cc430cca1f05a9fe6cf1bc 324 SUPERFAMILY SSF53822 23 310 5.42E-62 T 29-03-2018 IPR028082 Periplasmic binding protein-like I MC49_RS13855 567b739798cc430cca1f05a9fe6cf1bc 324 Gene3D G3DSA:3.40.50.2300 23 140 1.1E-19 T 29-03-2018 MC49_RS13855 567b739798cc430cca1f05a9fe6cf1bc 324 Pfam PF13407 Periplasmic binding protein domain 28 284 1.7E-49 T 29-03-2018 IPR025997 Periplasmic binding protein MC49_RS13855 567b739798cc430cca1f05a9fe6cf1bc 324 Gene3D G3DSA:3.40.50.2300 141 297 1.8E-12 T 29-03-2018 MC49_RS15560 250dce286a18abd94c7c235cb3dccd7e 544 SUPERFAMILY SSF53850 36 532 2.99E-138 T 29-03-2018 MC49_RS15560 250dce286a18abd94c7c235cb3dccd7e 544 Gene3D G3DSA:3.90.76.10 50 210 5.4E-41 T 29-03-2018 MC49_RS15560 250dce286a18abd94c7c235cb3dccd7e 544 Gene3D G3DSA:3.40.190.10 211 307 3.1E-21 T 29-03-2018 MC49_RS15560 250dce286a18abd94c7c235cb3dccd7e 544 Gene3D G3DSA:3.10.105.10 308 513 1.4E-58 T 29-03-2018 MC49_RS15560 250dce286a18abd94c7c235cb3dccd7e 544 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 83 460 1.2E-80 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain MC49_RS15560 250dce286a18abd94c7c235cb3dccd7e 544 PIRSF PIRSF002741 1 543 7.5E-113 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MC49_RS09420 673292352a1286b8a5b1531f804faa8b 402 SUPERFAMILY SSF46785 23 83 1.11E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS09420 673292352a1286b8a5b1531f804faa8b 402 Pfam PF00480 ROK family 91 393 4.7E-25 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 MC49_RS09420 673292352a1286b8a5b1531f804faa8b 402 Gene3D G3DSA:3.30.420.40 205 401 7.6E-27 T 29-03-2018 MC49_RS09420 673292352a1286b8a5b1531f804faa8b 402 SUPERFAMILY SSF53067 88 396 1.66E-26 T 29-03-2018 MC49_RS09420 673292352a1286b8a5b1531f804faa8b 402 Gene3D G3DSA:3.30.420.40 81 204 2.1E-8 T 29-03-2018 MC49_RS09420 673292352a1286b8a5b1531f804faa8b 402 Gene3D G3DSA:1.10.10.10 21 80 2.1E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS14610 819ac95b53428759dbdc33f23d72bf30 474 Gene3D G3DSA:3.50.50.60 48 474 7.6E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS14610 819ac95b53428759dbdc33f23d72bf30 474 SUPERFAMILY SSF51905 417 473 7.77E-49 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS14610 819ac95b53428759dbdc33f23d72bf30 474 SUPERFAMILY SSF51905 56 275 7.77E-49 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS14610 819ac95b53428759dbdc33f23d72bf30 474 Pfam PF01266 FAD dependent oxidoreductase 57 455 1.5E-52 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MC49_RS00990 fa4cb9953b8c018ace5dd44a962998ae 117 Gene3D G3DSA:3.30.1130.10 1 117 8.2E-35 T 29-03-2018 MC49_RS00990 fa4cb9953b8c018ace5dd44a962998ae 117 TIGRFAM TIGR00526 folB_dom: FolB domain 1 115 9.2E-34 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MC49_RS00990 fa4cb9953b8c018ace5dd44a962998ae 117 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 4 114 6.0E-28 T 29-03-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MC49_RS00990 fa4cb9953b8c018ace5dd44a962998ae 117 SMART SM00905 4 114 1.9E-42 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MC49_RS00990 fa4cb9953b8c018ace5dd44a962998ae 117 Pfam PF02152 Dihydroneopterin aldolase 4 113 3.8E-31 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MC49_RS00990 fa4cb9953b8c018ace5dd44a962998ae 117 SUPERFAMILY SSF55620 1 115 2.22E-34 T 29-03-2018 MC49_RS00210 f81cef5e1393fcac823b836a69f01095 467 Pfam PF09979 Uncharacterized protein conserved in bacteria (DUF2213) 52 180 1.6E-5 T 29-03-2018 IPR016913 Uncharacterised conserved protein UCP029215 MC49_RS04310 2b45e5afbaaf23f56a665635aae225b2 195 SUPERFAMILY SSF49401 30 194 1.53E-13 T 29-03-2018 IPR008966 Adhesion domain MC49_RS04310 2b45e5afbaaf23f56a665635aae225b2 195 Pfam PF00419 Fimbrial protein 30 194 8.2E-11 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS04310 2b45e5afbaaf23f56a665635aae225b2 195 Gene3D G3DSA:2.60.40.1090 28 195 2.3E-19 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS01960 8ff92e78898e389f59a16b977043ef07 113 Hamap MF_00213 Probable hydrogenase nickel incorporation protein HypA [hypA]. 1 113 23.618 T 29-03-2018 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 MC49_RS01960 8ff92e78898e389f59a16b977043ef07 113 ProSitePatterns PS01249 Hydrogenases expression/synthesis hypA family signature. 34 76 - T 29-03-2018 IPR020538 Hydrogenase nickel incorporation protein HypA/HybF, conserved site MC49_RS01960 8ff92e78898e389f59a16b977043ef07 113 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 112 4.6E-31 T 29-03-2018 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 MC49_RS01960 8ff92e78898e389f59a16b977043ef07 113 PIRSF PIRSF004761 1 113 6.2E-36 T 29-03-2018 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 MC49_RS01960 8ff92e78898e389f59a16b977043ef07 113 TIGRFAM TIGR00100 hypA: hydrogenase nickel insertion protein HypA 1 113 7.7E-35 T 29-03-2018 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 MC49_RS17890 61200c05580397513ffc9d3869859f7c 429 Pfam PF04261 Dyp-type peroxidase family 65 408 9.6E-93 T 29-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 MC49_RS17890 61200c05580397513ffc9d3869859f7c 429 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 65 408 3.2E-83 T 29-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 MC49_RS17890 61200c05580397513ffc9d3869859f7c 429 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 12 421 3.9E-134 T 29-03-2018 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 MC49_RS17890 61200c05580397513ffc9d3869859f7c 429 SUPERFAMILY SSF54909 58 416 8.94E-79 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel MC49_RS14120 635f1508082e76299564a2a7247ca397 110 Pfam PF00893 Small Multidrug Resistance protein 12 100 1.7E-24 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 MC49_RS14120 635f1508082e76299564a2a7247ca397 110 SUPERFAMILY SSF103481 12 109 2.75E-17 T 29-03-2018 MC49_RS02785 f3a900973fbffbf8c1f6dba3320e8af9 245 Pfam PF01514 Secretory protein of YscJ/FliF family 5 189 5.9E-21 T 29-03-2018 IPR006182 Secretory protein YscJ/FliF MC49_RS02785 f3a900973fbffbf8c1f6dba3320e8af9 245 TIGRFAM TIGR02544 III_secr_YscJ: type III secretion apparatus lipoprotein, YscJ/HrcJ family 9 195 1.9E-54 T 29-03-2018 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 MC49_RS02785 f3a900973fbffbf8c1f6dba3320e8af9 245 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 118 131 6.9E-12 T 29-03-2018 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 MC49_RS02785 f3a900973fbffbf8c1f6dba3320e8af9 245 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 78 91 6.9E-12 T 29-03-2018 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 MC49_RS02785 f3a900973fbffbf8c1f6dba3320e8af9 245 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 98 113 6.9E-12 T 29-03-2018 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 MC49_RS02785 f3a900973fbffbf8c1f6dba3320e8af9 245 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 26 36 6.9E-12 T 29-03-2018 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 MC49_RS02785 f3a900973fbffbf8c1f6dba3320e8af9 245 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 168 180 6.9E-12 T 29-03-2018 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 MC49_RS02785 f3a900973fbffbf8c1f6dba3320e8af9 245 Gene3D G3DSA:3.30.70.1530 24 75 6.1E-17 T 29-03-2018 MC49_RS08120 f602c2520be38ce59e23767a4da2271a 88 Gene3D G3DSA:2.30.30.400 10 83 1.8E-24 T 29-03-2018 MC49_RS08120 f602c2520be38ce59e23767a4da2271a 88 SUPERFAMILY SSF101744 1 85 2.14E-28 T 29-03-2018 IPR023534 Rof/RNase P-like Reactome: R-HSA-6784531 MC49_RS08120 f602c2520be38ce59e23767a4da2271a 88 Pfam PF07073 Modulator of Rho-dependent transcription termination (ROF) 9 83 2.7E-26 T 29-03-2018 IPR009778 Modulator of Rho-dependent transcription termination MC49_RS16520 26cfa338b969041003d10b3b293d1213 182 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 139 157 - T 29-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16520 26cfa338b969041003d10b3b293d1213 182 PIRSF PIRSF000216 13 182 2.0E-52 T 29-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16520 26cfa338b969041003d10b3b293d1213 182 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 40 181 2.0E-49 T 29-03-2018 MC49_RS16520 26cfa338b969041003d10b3b293d1213 182 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 38 181 4.0E-51 T 29-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16520 26cfa338b969041003d10b3b293d1213 182 Gene3D G3DSA:3.40.30.10 100 181 8.5E-14 T 29-03-2018 MC49_RS16520 26cfa338b969041003d10b3b293d1213 182 SUPERFAMILY SSF52833 31 181 1.68E-49 T 29-03-2018 IPR012336 Thioredoxin-like fold MC49_RS18585 035d916b7c374062672899ccb09263df 205 Gene3D G3DSA:3.40.50.300 1 205 2.0E-40 T 29-03-2018 MC49_RS18585 035d916b7c374062672899ccb09263df 205 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 2 196 26.987 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 MC49_RS18585 035d916b7c374062672899ccb09263df 205 SUPERFAMILY SSF52540 1 191 1.5E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS18585 035d916b7c374062672899ccb09263df 205 Pfam PF01121 Dephospho-CoA kinase 3 177 4.0E-72 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 MC49_RS18585 035d916b7c374062672899ccb09263df 205 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 180 5.8E-62 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 MC49_RS16500 a6c116b2da057bcbfd9533f773aea029 180 Gene3D G3DSA:3.30.70.20 18 70 1.2E-7 T 29-03-2018 MC49_RS16500 a6c116b2da057bcbfd9533f773aea029 180 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 16 137 7.6E-52 T 29-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16500 a6c116b2da057bcbfd9533f773aea029 180 Pfam PF12838 4Fe-4S dicluster domain 59 113 6.8E-12 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MC49_RS16500 a6c116b2da057bcbfd9533f773aea029 180 Gene3D G3DSA:3.30.70.20 104 170 3.9E-8 T 29-03-2018 MC49_RS16500 a6c116b2da057bcbfd9533f773aea029 180 SUPERFAMILY SSF54862 33 162 3.56E-30 T 29-03-2018 MC49_RS16500 a6c116b2da057bcbfd9533f773aea029 180 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 7 168 27.027 T 29-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16500 a6c116b2da057bcbfd9533f773aea029 180 Gene3D G3DSA:3.30.70.20 71 103 1.9E-14 T 29-03-2018 MC49_RS16500 a6c116b2da057bcbfd9533f773aea029 180 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 99 110 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MC49_RS15805 59011f9b87d262e92b6e81bad16eab5a 434 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 143 417 4.9E-82 T 29-03-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 MC49_RS15805 59011f9b87d262e92b6e81bad16eab5a 434 SUPERFAMILY SSF101960 40 429 2.75E-104 T 29-03-2018 MC49_RS15805 59011f9b87d262e92b6e81bad16eab5a 434 Pfam PF01458 Uncharacterized protein family (UPF0051) 179 403 3.7E-72 T 29-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 MC49_RS00130 3b393e0790fe298daceeddf8c319398a 1153 Pfam PF06120 Tail length tape measure protein 417 502 3.3E-11 T 29-03-2018 IPR009302 Tail length tape measure MC49_RS00130 3b393e0790fe298daceeddf8c319398a 1153 Gene3D G3DSA:1.20.120.330 381 561 2.3E-4 T 29-03-2018 MC49_RS00130 3b393e0790fe298daceeddf8c319398a 1153 TIGRFAM TIGR02675 tape_meas_nterm: tape measure domain 142 216 9.7E-24 T 29-03-2018 IPR013491 Caudovirus, tape measure, N-terminal MC49_RS00065 34becdce84638d874c752cc276a49816 140 SUPERFAMILY SSF52833 4 135 2.31E-37 T 29-03-2018 IPR012336 Thioredoxin-like fold MC49_RS00065 34becdce84638d874c752cc276a49816 140 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 4 116 3.5E-38 T 29-03-2018 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 MC49_RS00065 34becdce84638d874c752cc276a49816 140 Gene3D G3DSA:3.40.30.10 1 140 1.2E-39 T 29-03-2018 MC49_RS00065 34becdce84638d874c752cc276a49816 140 Pfam PF03960 ArsC family 7 114 4.4E-19 T 29-03-2018 IPR006660 Arsenate reductase-like MC49_RS12280 e811260089746d46a66faa9e2d1d2df8 60 Pfam PF10735 Protein of unknown function (DUF2526) 1 59 1.9E-15 T 29-03-2018 IPR019671 Protein of unknown function DUF2526 MC49_RS14450 348a9ee67acad6ed801fc84bb3e0cc6b 341 Pfam PF01212 Beta-eliminating lyase 17 290 3.9E-31 T 29-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 MC49_RS14450 348a9ee67acad6ed801fc84bb3e0cc6b 341 SUPERFAMILY SSF53383 1 337 5.45E-81 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS14450 348a9ee67acad6ed801fc84bb3e0cc6b 341 Gene3D G3DSA:3.40.640.10 1 245 4.4E-35 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS14450 348a9ee67acad6ed801fc84bb3e0cc6b 341 Gene3D G3DSA:3.90.1150.10 246 341 4.4E-19 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS11510 ee9b400b3418c6b7d55e5ddd766e8e37 262 Pfam PF00106 short chain dehydrogenase 6 197 5.9E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS11510 ee9b400b3418c6b7d55e5ddd766e8e37 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MC49_RS11510 ee9b400b3418c6b7d55e5ddd766e8e37 262 Gene3D G3DSA:3.40.50.720 3 248 1.8E-38 T 29-03-2018 MC49_RS11510 ee9b400b3418c6b7d55e5ddd766e8e37 262 SUPERFAMILY SSF51735 5 232 2.88E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS11510 ee9b400b3418c6b7d55e5ddd766e8e37 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 4.6E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS11510 ee9b400b3418c6b7d55e5ddd766e8e37 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 4.6E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS11510 ee9b400b3418c6b7d55e5ddd766e8e37 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 4.6E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS11510 ee9b400b3418c6b7d55e5ddd766e8e37 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 4.6E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS11510 ee9b400b3418c6b7d55e5ddd766e8e37 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 4.6E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MC49_RS07035 ee98da4a7c3ca7c9164ed3836dadc730 249 Pfam PF01925 Sulfite exporter TauE/SafE 15 241 5.4E-29 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MC49_RS09270 2002ec4f3a93511d85874f10699d000b 315 SUPERFAMILY SSF51621 8 250 1.26E-30 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MC49_RS09270 2002ec4f3a93511d85874f10699d000b 315 PIRSF PIRSF015582 1 309 1.1E-57 T 29-03-2018 IPR011206 Citrate lyase beta subunit-like MC49_RS09270 2002ec4f3a93511d85874f10699d000b 315 Gene3D G3DSA:3.20.20.360 6 280 1.3E-35 T 29-03-2018 MC49_RS09270 2002ec4f3a93511d85874f10699d000b 315 Pfam PF15617 C-C_Bond_Lyase of the TIM-Barrel fold 5 300 1.5E-106 T 29-03-2018 MC49_RS11925 50252b3d4ca1b1d7262597beb04a6188 450 Pfam PF05936 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE 19 444 3.8E-150 T 29-03-2018 IPR010263 Type VI secretion protein, VC_A0114 MC49_RS11925 50252b3d4ca1b1d7262597beb04a6188 450 TIGRFAM TIGR03353 VI_chp_4: type VI secretion protein, VC_A0114 family 5 446 1.4E-158 T 29-03-2018 IPR010263 Type VI secretion protein, VC_A0114 MC49_RS06500 9e68f77e159ea104d49e28800b7fb7fb 266 SUPERFAMILY SSF161098 19 265 2.06E-44 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS06500 9e68f77e159ea104d49e28800b7fb7fb 266 Gene3D G3DSA:1.10.3720.10 17 266 3.4E-39 T 29-03-2018 MC49_RS06500 9e68f77e159ea104d49e28800b7fb7fb 266 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 264 2.5E-11 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS08675 7cc5e3fd92f47707458ddac3cd4a3b79 455 Pfam PF00860 Permease family 34 415 4.0E-78 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 MC49_RS15365 5a05a14435ce43659d3ae5b3e6aa5d06 342 Gene3D G3DSA:3.40.50.2300 1 125 6.8E-30 T 29-03-2018 MC49_RS15365 5a05a14435ce43659d3ae5b3e6aa5d06 342 Pfam PF00072 Response regulator receiver domain 11 114 5.7E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS15365 5a05a14435ce43659d3ae5b3e6aa5d06 342 Hamap MF_00958 Regulator of RpoS [rssB]. 1 338 52.665 T 29-03-2018 IPR028616 Regulator of RpoS MC49_RS15365 5a05a14435ce43659d3ae5b3e6aa5d06 342 SUPERFAMILY SSF52172 6 113 2.13E-28 T 29-03-2018 IPR011006 CheY-like superfamily MC49_RS15365 5a05a14435ce43659d3ae5b3e6aa5d06 342 SMART SM00448 8 120 8.8E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MC49_RS13580 9353e393bb4496d4a3e286394cc03a01 710 SUPERFAMILY SSF82171 42 200 8.24E-6 T 29-03-2018 MC49_RS13580 9353e393bb4496d4a3e286394cc03a01 710 SUPERFAMILY SSF82171 246 348 8.24E-6 T 29-03-2018 MC49_RS13580 9353e393bb4496d4a3e286394cc03a01 710 Pfam PF03797 Autotransporter beta-domain 462 688 1.2E-11 T 29-03-2018 IPR005546 Autotransporter beta-domain MC49_RS13580 9353e393bb4496d4a3e286394cc03a01 710 SUPERFAMILY SSF103515 423 710 4.18E-21 T 29-03-2018 IPR005546 Autotransporter beta-domain MC49_RS13580 9353e393bb4496d4a3e286394cc03a01 710 Gene3D G3DSA:2.130.10.120 23 352 4.9E-5 T 29-03-2018 MC49_RS13580 9353e393bb4496d4a3e286394cc03a01 710 Gene3D G3DSA:2.40.128.130 442 708 2.1E-17 T 29-03-2018 MC49_RS13580 9353e393bb4496d4a3e286394cc03a01 710 TIGRFAM TIGR02913 HAF_rpt: probable extracellular repeat, HAF family 176 212 3.4E-6 T 29-03-2018 IPR014262 Extracellular HAF MC49_RS13580 9353e393bb4496d4a3e286394cc03a01 710 TIGRFAM TIGR02913 HAF_rpt: probable extracellular repeat, HAF family 222 261 6.4E-9 T 29-03-2018 IPR014262 Extracellular HAF MC49_RS07440 4bd65e326b99502717d76cbe7daff276 127 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 5 122 15.878 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 MC49_RS07440 4bd65e326b99502717d76cbe7daff276 127 TIGRFAM TIGR00494 crcB: protein CrcB 7 119 1.2E-27 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 MC49_RS07440 4bd65e326b99502717d76cbe7daff276 127 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 8 117 1.3E-20 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 MC49_RS16475 af1e9d3820cfe9f404a374d0ae25e1d7 485 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 6 475 17.46 T 29-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 MC49_RS16475 af1e9d3820cfe9f404a374d0ae25e1d7 485 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 9 474 1.7E-128 T 29-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 MC49_RS16475 af1e9d3820cfe9f404a374d0ae25e1d7 485 Pfam PF00361 Proton-conducting membrane transporter 122 420 6.8E-80 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS05515 b265e78bdb82607641d516902059c70b 287 Pfam PF03755 YicC-like family, N-terminal region 2 153 1.2E-44 T 29-03-2018 IPR013527 YicC-like, N-terminal MC49_RS05515 b265e78bdb82607641d516902059c70b 287 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 287 1.2E-126 T 29-03-2018 IPR005229 Conserved hypothetical protein CHP00255 MC49_RS05515 b265e78bdb82607641d516902059c70b 287 Pfam PF08340 Domain of unknown function (DUF1732) 203 287 2.4E-34 T 29-03-2018 IPR013551 Domain of unknown function DUF1732 MC49_RS06190 a463088e0ac25f87a0ef8b18b44a82b5 102 Gene3D G3DSA:1.20.5.780 17 95 3.0E-22 T 29-03-2018 MC49_RS06190 a463088e0ac25f87a0ef8b18b44a82b5 102 SUPERFAMILY SSF47598 18 94 4.15E-17 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 MC49_RS06190 a463088e0ac25f87a0ef8b18b44a82b5 102 Pfam PF08681 Protein of unknown function (DUF1778) 21 94 3.2E-22 T 29-03-2018 IPR014795 Vibrio phage ICP1, Orf50 MC49_RS17310 ee12afbd37965ad4547a8196a74c58bc 157 Pfam PF00313 'Cold-shock' DNA-binding domain 1 62 1.0E-8 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MC49_RS17310 ee12afbd37965ad4547a8196a74c58bc 157 Gene3D G3DSA:2.40.50.140 1 70 3.0E-14 T 29-03-2018 MC49_RS17310 ee12afbd37965ad4547a8196a74c58bc 157 SUPERFAMILY SSF50249 2 62 1.62E-10 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold MC49_RS00150 ae85d5f7fd8364f7f04bfb0650a9e2da 76 Gene3D G3DSA:1.10.1220.10 1 75 4.1E-17 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 MC49_RS00150 ae85d5f7fd8364f7f04bfb0650a9e2da 76 Pfam PF03869 Arc-like DNA binding domain 7 49 1.1E-11 T 29-03-2018 IPR005569 Arc-like DNA binding domain GO:0003677 MC49_RS00150 ae85d5f7fd8364f7f04bfb0650a9e2da 76 SUPERFAMILY SSF47598 7 52 7.78E-12 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 MC49_RS18250 828e7351477f80b1a830e0531e6059b3 82 Pfam PF10678 Protein of unknown function (DUF2492) 6 81 1.3E-34 T 29-03-2018 IPR019620 Putative metal-binding protein MC49_RS18250 828e7351477f80b1a830e0531e6059b3 82 TIGRFAM TIGR03853 matur_matur: putative metal-binding protein 6 82 2.0E-34 T 29-03-2018 IPR019620 Putative metal-binding protein MC49_RS02085 2ecd1908293917bd31cc34c5258011ae 342 PIRSF PIRSF004911 3 342 4.9E-115 T 29-03-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase MC49_RS02085 2ecd1908293917bd31cc34c5258011ae 342 Gene3D G3DSA:3.20.20.70 102 329 1.2E-16 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS02085 2ecd1908293917bd31cc34c5258011ae 342 TIGRFAM TIGR03821 EFP_modif_epmB: EF-P beta-lysylation protein EpmB 15 335 1.5E-153 T 29-03-2018 IPR022462 Lysine-2,3-aminomutase-like MC49_RS02085 2ecd1908293917bd31cc34c5258011ae 342 Pfam PF13353 4Fe-4S single cluster domain 112 175 2.2E-6 T 29-03-2018 MC49_RS02085 2ecd1908293917bd31cc34c5258011ae 342 Pfam PF04055 Radical SAM superfamily 118 232 3.3E-8 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MC49_RS02085 2ecd1908293917bd31cc34c5258011ae 342 SUPERFAMILY SSF102114 102 324 1.09E-24 T 29-03-2018 MC49_RS02085 2ecd1908293917bd31cc34c5258011ae 342 TIGRFAM TIGR00238 TIGR00238: KamA family protein 3 328 4.2E-131 T 29-03-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase MC49_RS18335 dc9e30b0e9963acc15e9a5a403c106c5 231 Gene3D G3DSA:1.10.10.10 189 229 0.29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS18335 dc9e30b0e9963acc15e9a5a403c106c5 231 SMART SM00418 15 94 4.7E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MC49_RS18335 dc9e30b0e9963acc15e9a5a403c106c5 231 SUPERFAMILY SSF46785 8 95 2.09E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS18335 dc9e30b0e9963acc15e9a5a403c106c5 231 Gene3D G3DSA:1.10.10.10 1 184 1.2E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS18335 dc9e30b0e9963acc15e9a5a403c106c5 231 Pfam PF12840 Helix-turn-helix domain 16 73 4.2E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS11210 027e5ea625403ba137c1ae930b6253c3 182 Pfam PF05951 Bacterial protein of unknown function (DUF882) 34 182 2.6E-59 T 29-03-2018 IPR010275 Protein of unknown function DUF882 MC49_RS11210 027e5ea625403ba137c1ae930b6253c3 182 Gene3D G3DSA:3.30.1380.10 49 182 3.6E-22 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MC49_RS11210 027e5ea625403ba137c1ae930b6253c3 182 SUPERFAMILY SSF55166 68 182 1.62E-31 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MC49_RS00145 86c417815506cd4c765d4482a74e6cf6 53 SUPERFAMILY SSF47598 2 46 6.23E-7 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 MC49_RS00145 86c417815506cd4c765d4482a74e6cf6 53 Gene3D G3DSA:1.10.1220.10 2 53 2.1E-6 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 MC49_RS00145 86c417815506cd4c765d4482a74e6cf6 53 Pfam PF03869 Arc-like DNA binding domain 9 48 4.2E-7 T 29-03-2018 IPR005569 Arc-like DNA binding domain GO:0003677 MC49_RS14705 b0a769cf2ef95716960e9ac3713e4346 330 Gene3D G3DSA:3.40.50.1980 138 311 2.8E-39 T 29-03-2018 MC49_RS14705 b0a769cf2ef95716960e9ac3713e4346 330 SUPERFAMILY SSF53807 26 329 1.96E-59 T 29-03-2018 MC49_RS14705 b0a769cf2ef95716960e9ac3713e4346 330 Gene3D G3DSA:3.40.50.1980 20 137 2.0E-15 T 29-03-2018 MC49_RS14705 b0a769cf2ef95716960e9ac3713e4346 330 Pfam PF01497 Periplasmic binding protein 37 266 1.2E-25 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 MC49_RS04460 1bacbfc98bba99848cf326e1421eed0f 325 Gene3D G3DSA:3.40.190.10 184 268 5.7E-17 T 29-03-2018 MC49_RS04460 1bacbfc98bba99848cf326e1421eed0f 325 SUPERFAMILY SSF46785 1 86 2.67E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS04460 1bacbfc98bba99848cf326e1421eed0f 325 Pfam PF03466 LysR substrate binding domain 93 292 2.3E-38 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS04460 1bacbfc98bba99848cf326e1421eed0f 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.6E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS04460 1bacbfc98bba99848cf326e1421eed0f 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.6E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS04460 1bacbfc98bba99848cf326e1421eed0f 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.6E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS04460 1bacbfc98bba99848cf326e1421eed0f 325 Gene3D G3DSA:1.10.10.10 1 85 3.6E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS04460 1bacbfc98bba99848cf326e1421eed0f 325 Gene3D G3DSA:3.40.190.10 89 183 3.7E-24 T 29-03-2018 MC49_RS04460 1bacbfc98bba99848cf326e1421eed0f 325 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 64 1.4E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS04460 1bacbfc98bba99848cf326e1421eed0f 325 SUPERFAMILY SSF53850 93 296 1.3E-38 T 29-03-2018 MC49_RS11245 80e65a866b1408d1e239faf7186f26f0 409 Pfam PF04536 TPM domain 41 163 6.9E-41 T 29-03-2018 IPR007621 TPM domain MC49_RS04600 371144581a85b754b06dc6e52ac61e04 228 SUPERFAMILY SSF49354 23 138 1.41E-29 T 29-03-2018 IPR008962 PapD-like MC49_RS04600 371144581a85b754b06dc6e52ac61e04 228 PRINTS PR00969 Pili chaperone signature 120 135 3.3E-20 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS04600 371144581a85b754b06dc6e52ac61e04 228 PRINTS PR00969 Pili chaperone signature 96 113 3.3E-20 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS04600 371144581a85b754b06dc6e52ac61e04 228 PRINTS PR00969 Pili chaperone signature 24 33 3.3E-20 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS04600 371144581a85b754b06dc6e52ac61e04 228 PRINTS PR00969 Pili chaperone signature 157 172 3.3E-20 T 29-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 MC49_RS04600 371144581a85b754b06dc6e52ac61e04 228 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 162 221 5.5E-15 T 29-03-2018 IPR016148 Pili assembly chaperone, C-terminal MC49_RS04600 371144581a85b754b06dc6e52ac61e04 228 Gene3D G3DSA:2.60.40.10 25 136 2.1E-25 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS04600 371144581a85b754b06dc6e52ac61e04 228 Gene3D G3DSA:2.60.40.10 143 228 3.9E-22 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS04600 371144581a85b754b06dc6e52ac61e04 228 SUPERFAMILY SSF49584 143 226 1.27E-20 T 29-03-2018 IPR016148 Pili assembly chaperone, C-terminal MC49_RS04600 371144581a85b754b06dc6e52ac61e04 228 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 24 138 7.5E-30 T 29-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 MC49_RS06150 0342f38d1c52ea0932f890b6dcdd219e 235 Pfam PF17154 Gammaproteobacterial periplasmic sensor domain 38 158 3.1E-51 T 29-03-2018 IPR033419 Gammaproteobacterial periplasmic sensor domain GAPES3 MC49_RS01370 5a45d6e1fa6fa4dcdd80f18ac4178349 128 Pfam PF07681 DoxX 5 85 2.5E-16 T 29-03-2018 IPR032808 DoxX family MC49_RS02340 c714dd9aa14c1869ab961f228a33c7b3 111 Pfam PF08274 PhnA Zinc-Ribbon 2 30 5.4E-16 T 29-03-2018 IPR013987 PhnA protein, N-terminal MC49_RS02340 c714dd9aa14c1869ab961f228a33c7b3 111 Pfam PF03831 PhnA domain 44 110 2.2E-34 T 29-03-2018 IPR013988 PhnA protein, C-terminal MC49_RS02340 c714dd9aa14c1869ab961f228a33c7b3 111 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 2 110 3.4E-60 T 29-03-2018 IPR004624 PhnA protein MC49_RS02340 c714dd9aa14c1869ab961f228a33c7b3 111 SUPERFAMILY SSF82057 39 110 2.29E-29 T 29-03-2018 MC49_RS02340 c714dd9aa14c1869ab961f228a33c7b3 111 Gene3D G3DSA:2.30.30.40 43 110 5.8E-37 T 29-03-2018 MC49_RS02340 c714dd9aa14c1869ab961f228a33c7b3 111 SUPERFAMILY SSF57783 1 35 9.86E-15 T 29-03-2018 MC49_RS02340 c714dd9aa14c1869ab961f228a33c7b3 111 Gene3D G3DSA:2.20.25.10 1 39 7.3E-18 T 29-03-2018 MC49_RS09990 92d1d69230d7fb1fd53c4ed05ad1524a 234 SMART SM01144 27 219 7.0E-73 T 29-03-2018 IPR005636 DTW MC49_RS09990 92d1d69230d7fb1fd53c4ed05ad1524a 234 Pfam PF03942 DTW domain 30 213 1.2E-42 T 29-03-2018 IPR005636 DTW MC49_RS18570 5a1bfef6a775c8528a82ccf4a58c59a0 139 Gene3D G3DSA:3.30.700.10 6 134 4.3E-24 T 29-03-2018 MC49_RS18570 5a1bfef6a775c8528a82ccf4a58c59a0 139 SUPERFAMILY SSF54523 6 117 1.1E-22 T 29-03-2018 MC49_RS18570 5a1bfef6a775c8528a82ccf4a58c59a0 139 PRINTS PR00813 Bacterial general secretion pathway protein G signature 5 30 2.1E-9 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 MC49_RS18570 5a1bfef6a775c8528a82ccf4a58c59a0 139 PRINTS PR00813 Bacterial general secretion pathway protein G signature 41 59 2.1E-9 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 MC49_RS18570 5a1bfef6a775c8528a82ccf4a58c59a0 139 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 4 24 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site MC49_RS18570 5a1bfef6a775c8528a82ccf4a58c59a0 139 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 25 2.3E-10 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site MC49_RS18570 5a1bfef6a775c8528a82ccf4a58c59a0 139 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 3 26 1.8E-10 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site MC49_RS19105 2c0a3e8a97a6d7d7aa9d3dd4e73f1273 144 SUPERFAMILY SSF53062 1 130 4.19E-32 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 MC49_RS19105 2c0a3e8a97a6d7d7aa9d3dd4e73f1273 144 Gene3D G3DSA:3.40.50.510 1 144 1.5E-30 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 MC49_RS19105 2c0a3e8a97a6d7d7aa9d3dd4e73f1273 144 Pfam PF03610 PTS system fructose IIA component 3 115 3.0E-26 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 MC49_RS17150 ef43283911f1288a1079790699cd0ac7 472 Pfam PF00929 Exonuclease 8 183 4.0E-25 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MC49_RS17150 ef43283911f1288a1079790699cd0ac7 472 SUPERFAMILY SSF53098 6 470 5.21E-133 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MC49_RS17150 ef43283911f1288a1079790699cd0ac7 472 Pfam PF08411 Exonuclease C-terminal 207 468 1.6E-106 T 29-03-2018 IPR013620 Exodeoxyribonuclease I, C-terminal GO:0006281|GO:0008852 MC49_RS17150 ef43283911f1288a1079790699cd0ac7 472 Gene3D G3DSA:3.30.420.10 1 196 1.6E-24 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MC49_RS17150 ef43283911f1288a1079790699cd0ac7 472 PIRSF PIRSF000977 1 472 1.0E-201 T 29-03-2018 IPR023607 Exodeoxyribonuclease I GO:0004529 MC49_RS14435 6371f6e49daacfb8bd7aa6042c641fb0 153 Gene3D G3DSA:3.90.79.10 2 153 3.5E-21 T 29-03-2018 MC49_RS14435 6371f6e49daacfb8bd7aa6042c641fb0 153 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MC49_RS14435 6371f6e49daacfb8bd7aa6042c641fb0 153 PRINTS PR00502 NUDIX hydrolase family signature 32 46 5.3E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MC49_RS14435 6371f6e49daacfb8bd7aa6042c641fb0 153 PRINTS PR00502 NUDIX hydrolase family signature 46 61 5.3E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MC49_RS14435 6371f6e49daacfb8bd7aa6042c641fb0 153 SUPERFAMILY SSF55811 7 145 9.61E-23 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MC49_RS14435 6371f6e49daacfb8bd7aa6042c641fb0 153 Pfam PF00293 NUDIX domain 7 139 5.2E-15 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MC49_RS07600 881f7c29a16e158f6b3aff765b573835 314 PIRSF PIRSF004491 1 312 7.6E-105 T 29-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 MC49_RS07600 881f7c29a16e158f6b3aff765b573835 314 Pfam PF01687 Riboflavin kinase 184 306 1.5E-36 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 MC49_RS07600 881f7c29a16e158f6b3aff765b573835 314 SMART SM00904 183 307 1.7E-57 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 MC49_RS07600 881f7c29a16e158f6b3aff765b573835 314 Gene3D G3DSA:2.40.30.30 180 312 1.6E-38 T 29-03-2018 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 MC49_RS07600 881f7c29a16e158f6b3aff765b573835 314 Gene3D G3DSA:3.40.50.620 1 179 2.8E-52 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS07600 881f7c29a16e158f6b3aff765b573835 314 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 18 307 2.2E-112 T 29-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 MC49_RS07600 881f7c29a16e158f6b3aff765b573835 314 Pfam PF06574 FAD synthetase 12 167 1.2E-59 T 29-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 MC49_RS07600 881f7c29a16e158f6b3aff765b573835 314 SUPERFAMILY SSF82114 174 308 7.19E-43 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 MC49_RS07600 881f7c29a16e158f6b3aff765b573835 314 SUPERFAMILY SSF52374 15 175 1.49E-35 T 29-03-2018 MC49_RS10415 9d33b15320020b54022a246a99a97bfc 94 Pfam PF09600 Cyd operon protein YbgE (Cyd_oper_YbgE) 14 91 4.1E-30 T 29-03-2018 IPR011846 Cyd operon protein YbgE MC49_RS10415 9d33b15320020b54022a246a99a97bfc 94 TIGRFAM TIGR02112 cyd_oper_ybgE: cyd operon protein YbgE 3 93 2.9E-32 T 29-03-2018 IPR011846 Cyd operon protein YbgE MC49_RS06025 620856bece0fe2dc29303ce92d463adc 145 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 145 2.1E-67 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 MC49_RS06025 620856bece0fe2dc29303ce92d463adc 145 SUPERFAMILY SSF69500 1 144 6.41E-54 T 29-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain MC49_RS06025 620856bece0fe2dc29303ce92d463adc 145 Gene3D G3DSA:3.50.80.10 1 145 5.8E-52 T 29-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain MC49_RS06025 620856bece0fe2dc29303ce92d463adc 145 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 34.216 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 MC49_RS06025 620856bece0fe2dc29303ce92d463adc 145 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 3 143 4.7E-51 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 MC49_RS07375 f69be38abf7e9fcaec78213577eff072 322 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 318 3.9E-37 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS07375 f69be38abf7e9fcaec78213577eff072 322 SUPERFAMILY SSF161098 95 311 8.37E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS07375 f69be38abf7e9fcaec78213577eff072 322 Gene3D G3DSA:1.10.3720.10 85 317 1.1E-28 T 29-03-2018 MC49_RS19100 2d812a2b98bbf33d7c4514e88002704c 291 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 35 290 2.8E-91 T 29-03-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 MC49_RS15025 6de6858aef0c402492faae348c553060 202 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 146 157 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MC49_RS15025 6de6858aef0c402492faae348c553060 202 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 1 187 1.2E-86 T 29-03-2018 IPR010207 Electron transport complex, RnfB/RsxB GO:0009055|GO:0051536 MC49_RS15025 6de6858aef0c402492faae348c553060 202 Hamap MF_00463 Electron transport complex subunit RsxB [rsxB]. 4 184 42.751 T 29-03-2018 IPR016463 Electron transport complex, RnfB/RsxB, Proteobacteria GO:0005886|GO:0022900|GO:0051536 MC49_RS15025 6de6858aef0c402492faae348c553060 202 Gene3D G3DSA:3.30.70.20 151 179 0.0015 T 29-03-2018 MC49_RS15025 6de6858aef0c402492faae348c553060 202 SUPERFAMILY SSF54862 37 175 8.05E-29 T 29-03-2018 MC49_RS15025 6de6858aef0c402492faae348c553060 202 Gene3D G3DSA:3.30.70.20 23 119 1.8E-10 T 29-03-2018 MC49_RS15025 6de6858aef0c402492faae348c553060 202 Pfam PF14697 4Fe-4S dicluster domain 109 163 3.2E-17 T 29-03-2018 MC49_RS15025 6de6858aef0c402492faae348c553060 202 Gene3D G3DSA:3.30.70.20 120 150 1.7E-12 T 29-03-2018 MC49_RS15025 6de6858aef0c402492faae348c553060 202 Pfam PF04060 Putative Fe-S cluster 44 75 5.3E-12 T 29-03-2018 IPR007202 4Fe-4S domain GO:0051536 MC49_RS15025 6de6858aef0c402492faae348c553060 202 PIRSF PIRSF005784 3 189 7.6E-84 T 29-03-2018 IPR016463 Electron transport complex, RnfB/RsxB, Proteobacteria GO:0005886|GO:0022900|GO:0051536 MC49_RS17900 039e0efce9a5db1c378425e8c2f16982 279 Pfam PF03239 Iron permease FTR1 family 3 262 2.3E-25 T 29-03-2018 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0006827|GO:0016020|GO:0033573 MC49_RS01590 f6278c131987f4e0ad159c223dba78a4 95 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 95 1.5E-30 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 MC49_RS01590 f6278c131987f4e0ad159c223dba78a4 95 Gene3D G3DSA:3.30.160.100 1 95 4.0E-30 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 MC49_RS01590 f6278c131987f4e0ad159c223dba78a4 95 SUPERFAMILY SSF69754 1 95 9.42E-32 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 MC49_RS01590 f6278c131987f4e0ad159c223dba78a4 95 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 93 5.6E-26 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 MC49_RS18030 11fb763ba4c01821de768727b588b103 169 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 23 143 2.2E-50 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 MC49_RS18030 11fb763ba4c01821de768727b588b103 169 Gene3D G3DSA:2.70.70.10 9 169 4.8E-58 T 29-03-2018 MC49_RS18030 11fb763ba4c01821de768727b588b103 169 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 22 146 1.4E-49 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 MC49_RS18030 11fb763ba4c01821de768727b588b103 169 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 85 97 - T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 MC49_RS18030 11fb763ba4c01821de768727b588b103 169 SUPERFAMILY SSF51261 12 167 4.19E-56 T 29-03-2018 IPR011055 Duplicated hybrid motif MC49_RS07420 2f252ee36331b3eab8dcea7a8781ef5b 321 Pfam PF01774 UreD urease accessory protein 88 293 1.2E-43 T 29-03-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 MC49_RS07420 2f252ee36331b3eab8dcea7a8781ef5b 321 Hamap MF_01384 Urease accessory protein UreD [ureD]. 44 306 23.107 T 29-03-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 MC49_RS10910 6ba290e0ed2921401c6aacc2665807d1 15 Pfam PF08047 Histidine operon leader peptide 1 15 1.7E-8 T 29-03-2018 IPR012565 Histidine operon leader peptide GO:0000105 MC49_RS12675 9342fb04a20cbcb815097218a18548e2 126 TIGRFAM TIGR00494 crcB: protein CrcB 8 125 1.8E-25 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 MC49_RS12675 9342fb04a20cbcb815097218a18548e2 126 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 8 121 1.6E-22 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 MC49_RS12675 9342fb04a20cbcb815097218a18548e2 126 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 6 126 18.034 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 MC49_RS04560 1007ff307a24d2b5a71fbaa24070ef5b 436 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 10 422 7.1E-110 T 29-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit MC49_RS04560 1007ff307a24d2b5a71fbaa24070ef5b 436 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 21 427 3.1E-137 T 29-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 MC49_RS04560 1007ff307a24d2b5a71fbaa24070ef5b 436 PIRSF PIRSF006066 4 433 4.4E-163 T 29-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 MC49_RS08220 b3369959b771b9db40b7f524086e5d91 104 Pfam PF04977 Septum formation initiator 11 88 7.5E-27 T 29-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 MC49_RS08220 b3369959b771b9db40b7f524086e5d91 104 Hamap MF_00599 Cell division protein FtsB [ftsB]. 1 90 33.522 T 29-03-2018 IPR023081 Cell division protein FtsB MC49_RS07120 8b0cd02caa9c6a1f85a25f2a9b1d6b6e 176 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 40 58 1.4E-31 T 29-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 MC49_RS07120 8b0cd02caa9c6a1f85a25f2a9b1d6b6e 176 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 1.4E-31 T 29-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 MC49_RS07120 8b0cd02caa9c6a1f85a25f2a9b1d6b6e 176 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 1.4E-31 T 29-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 MC49_RS07120 8b0cd02caa9c6a1f85a25f2a9b1d6b6e 176 Gene3D G3DSA:1.20.5.1230 24 153 2.1E-4 T 29-03-2018 MC49_RS07120 8b0cd02caa9c6a1f85a25f2a9b1d6b6e 176 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 2 80 1.2E-29 T 29-03-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 MC49_RS07120 8b0cd02caa9c6a1f85a25f2a9b1d6b6e 176 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 1 164 18.789 T 29-03-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 MC49_RS10145 bc2ef6af4aeb0a76141728495112ee91 347 SUPERFAMILY SSF52540 2 210 1.77E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS10145 bc2ef6af4aeb0a76141728495112ee91 347 Gene3D G3DSA:1.10.8.60 143 222 2.5E-19 T 29-03-2018 MC49_RS10145 bc2ef6af4aeb0a76141728495112ee91 347 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 20 331 5.9E-93 T 29-03-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 MC49_RS10145 bc2ef6af4aeb0a76141728495112ee91 347 SUPERFAMILY SSF48019 212 334 1.68E-27 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 MC49_RS10145 bc2ef6af4aeb0a76141728495112ee91 347 Pfam PF06144 DNA polymerase III, delta subunit 21 190 3.0E-42 T 29-03-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 MC49_RS10145 bc2ef6af4aeb0a76141728495112ee91 347 Pfam PF14840 Processivity clamp loader gamma complex DNA pol III C-term 214 335 3.0E-50 T 29-03-2018 IPR032780 DNA polymerase III subunit delta, C-terminal KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS10145 bc2ef6af4aeb0a76141728495112ee91 347 Gene3D G3DSA:3.40.50.300 1 140 2.2E-21 T 29-03-2018 MC49_RS10145 bc2ef6af4aeb0a76141728495112ee91 347 Gene3D G3DSA:1.20.272.10 223 342 3.6E-21 T 29-03-2018 MC49_RS00515 35653b56c30956ae3aba730c8e0a9256 494 Pfam PF03577 Peptidase family C69 21 420 1.8E-120 T 29-03-2018 IPR005322 Peptidase C69, dipeptidase A GO:0006508|GO:0016805 MC49_RS00515 35653b56c30956ae3aba730c8e0a9256 494 Gene3D G3DSA:3.60.60.10 19 471 1.9E-37 T 29-03-2018 MC49_RS17145 5b6fa12b68efc2acbe2b5e50cacb4822 108 Pfam PF04363 Protein of unknown function (DUF496) 9 100 1.1E-45 T 29-03-2018 IPR007458 Protein of unknown function DUF496 MC49_RS17145 5b6fa12b68efc2acbe2b5e50cacb4822 108 Hamap MF_00683 UPF0265 protein YeeX [yeeX]. 9 103 25.088 T 29-03-2018 IPR007458 Protein of unknown function DUF496 MC49_RS17145 5b6fa12b68efc2acbe2b5e50cacb4822 108 PIRSF PIRSF028773 1 108 5.5E-50 T 29-03-2018 IPR007458 Protein of unknown function DUF496 MC49_RS17145 5b6fa12b68efc2acbe2b5e50cacb4822 108 ProDom PD030876 UPF0265 YEEX HELIX ALPHA BFL460 UNCHARACTERIZED FN0411 HI1168 VPA1226 BCR 12 99 1.0E-38 T 29-03-2018 IPR007458 Protein of unknown function DUF496 MC49_RS14865 08048a59b1d19379d0ab24a28a1d71c5 192 SUPERFAMILY SSF46689 20 79 5.08E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS14865 08048a59b1d19379d0ab24a28a1d71c5 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 2.0E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS14865 08048a59b1d19379d0ab24a28a1d71c5 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 2.0E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS14865 08048a59b1d19379d0ab24a28a1d71c5 192 Gene3D G3DSA:1.10.357.10 14 191 9.2E-20 T 29-03-2018 MC49_RS14865 08048a59b1d19379d0ab24a28a1d71c5 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 69 4.6E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS10655 ad5c3e1822f39e3e1ad121cf1dd79a36 332 Gene3D G3DSA:1.20.1600.10 177 262 6.0E-9 T 29-03-2018 MC49_RS10655 ad5c3e1822f39e3e1ad121cf1dd79a36 332 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 164 319 2.6E-15 T 29-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MC49_RS10655 ad5c3e1822f39e3e1ad121cf1dd79a36 332 SUPERFAMILY SSF111369 42 123 2.88E-7 T 29-03-2018 MC49_RS10655 ad5c3e1822f39e3e1ad121cf1dd79a36 332 Gene3D G3DSA:2.40.50.100 43 141 6.9E-12 T 29-03-2018 MC49_RS10655 ad5c3e1822f39e3e1ad121cf1dd79a36 332 SUPERFAMILY SSF111369 174 295 8.37E-13 T 29-03-2018 MC49_RS12360 3f6fea2b2df7f5b2e5965d0da81654f6 85 ProDom PD060858 YCEP CYTOPLASMIC STY1199 ESCHERICHIA COLI SIMILAR ECS1438 1 76 6.0E-28 T 29-03-2018 IPR025730 Biofilm regulator BssS MC49_RS12360 3f6fea2b2df7f5b2e5965d0da81654f6 85 Pfam PF13991 BssS protein family 11 80 2.8E-39 T 29-03-2018 IPR025730 Biofilm regulator BssS MC49_RS10780 95bf9aadcfdf5d778904786bf27e3bc5 231 TIGRFAM TIGR00659 TIGR00659: TIGR00659 family protein 4 226 1.8E-94 T 29-03-2018 IPR005261 Conserved hypothetical protein CHP00659 MC49_RS10780 95bf9aadcfdf5d778904786bf27e3bc5 231 Pfam PF04172 LrgB-like family 12 223 8.6E-77 T 29-03-2018 IPR007300 CidB/LrgB family MC49_RS06730 dcdcf75ff838d9f581cece56a3eae7af 109 SUPERFAMILY SSF143011 20 81 1.83E-7 T 29-03-2018 IPR035095 Toxin RelE-like domain MC49_RS06730 dcdcf75ff838d9f581cece56a3eae7af 109 Gene3D G3DSA:3.30.2310.20 1 108 1.6E-23 T 29-03-2018 MC49_RS02430 3838129a897d8d128ce1bff6a3de69e7 160 Gene3D G3DSA:2.60.40.1090 24 160 8.2E-8 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS02430 3838129a897d8d128ce1bff6a3de69e7 160 Pfam PF00419 Fimbrial protein 30 160 2.6E-9 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS02430 3838129a897d8d128ce1bff6a3de69e7 160 SUPERFAMILY SSF49401 34 160 1.19E-18 T 29-03-2018 IPR008966 Adhesion domain MC49_RS16480 c465664eac6d0faa250639c5a7e5502e 506 Pfam PF00361 Proton-conducting membrane transporter 133 426 4.2E-70 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16480 c465664eac6d0faa250639c5a7e5502e 506 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 3 495 4.5E-176 T 29-03-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16480 c465664eac6d0faa250639c5a7e5502e 506 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 249 273 2.5E-37 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16480 c465664eac6d0faa250639c5a7e5502e 506 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 174 198 2.5E-37 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16480 c465664eac6d0faa250639c5a7e5502e 506 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 337 356 2.5E-37 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16480 c465664eac6d0faa250639c5a7e5502e 506 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 139 158 2.5E-37 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS16480 c465664eac6d0faa250639c5a7e5502e 506 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 389 415 2.5E-37 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MC49_RS03320 fd64b6c035f6d535274952202e300508 387 Gene3D G3DSA:3.40.1710.10 36 194 2.6E-29 T 29-03-2018 MC49_RS03320 fd64b6c035f6d535274952202e300508 387 Pfam PF12698 ABC-2 family transporter protein 24 359 1.1E-30 T 29-03-2018 MC49_RS03585 1f598b87b1f0f7c62df471e2a778e51d 425 SMART SM00244 95 255 2.9E-39 T 29-03-2018 IPR001107 Band 7 domain MC49_RS03585 1f598b87b1f0f7c62df471e2a778e51d 425 SUPERFAMILY SSF117892 128 259 1.31E-21 T 29-03-2018 IPR001107 Band 7 domain MC49_RS03585 1f598b87b1f0f7c62df471e2a778e51d 425 Pfam PF01145 SPFH domain / Band 7 family 99 270 2.0E-29 T 29-03-2018 IPR001107 Band 7 domain MC49_RS03585 1f598b87b1f0f7c62df471e2a778e51d 425 Pfam PF12221 Bacterial membrane protein N terminal 1 57 2.5E-12 T 29-03-2018 IPR020980 Menbrane protein HflK, N-terminal MC49_RS03585 1f598b87b1f0f7c62df471e2a778e51d 425 TIGRFAM TIGR01933 hflK: HflK protein 97 355 3.5E-111 T 29-03-2018 IPR010201 HflK GO:0016021 MC49_RS10835 0e03f563a75a44c340abcf6be156773f 292 SUPERFAMILY SSF144091 23 228 9.42E-34 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 MC49_RS10835 0e03f563a75a44c340abcf6be156773f 292 Gene3D G3DSA:1.20.1540.10 22 229 1.7E-33 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 MC49_RS10835 0e03f563a75a44c340abcf6be156773f 292 Pfam PF01694 Rhomboid family 67 228 9.3E-30 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 MC49_RS03055 40a46d43d844b985521fc6e90843467f 464 Pfam PF03611 PTS system sugar-specific permease component 10 404 1.7E-127 T 29-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 MC49_RS08690 107637bd258ee5e3e9f8524216a27ba9 257 SUPERFAMILY SSF56176 4 154 5.14E-24 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 MC49_RS08690 107637bd258ee5e3e9f8524216a27ba9 257 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 4 147 5.5E-21 T 29-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 MC49_RS08690 107637bd258ee5e3e9f8524216a27ba9 257 SMART SM01092 161 251 4.4E-6 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal MC49_RS08690 107637bd258ee5e3e9f8524216a27ba9 257 Gene3D G3DSA:3.30.390.50 158 257 4.8E-12 T 29-03-2018 MC49_RS08690 107637bd258ee5e3e9f8524216a27ba9 257 Gene3D G3DSA:3.30.465.10 54 156 5.2E-17 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 MC49_RS08690 107637bd258ee5e3e9f8524216a27ba9 257 SUPERFAMILY SSF55447 165 252 4.71E-12 T 29-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal MC49_RS08690 107637bd258ee5e3e9f8524216a27ba9 257 TIGRFAM TIGR03312 Se_sel_red_FAD: probable selenate reductase, FAD-binding subunit 2 257 7.6E-107 T 29-03-2018 IPR017698 Probable selenate reductase, FAD-binding subunit MC49_RS17200 4fca851a1d7301e556f27cfc6734b517 493 Pfam PF00324 Amino acid permease 24 481 1.6E-142 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 MC49_RS17200 4fca851a1d7301e556f27cfc6734b517 493 ProSitePatterns PS00218 Amino acid permeases signature. 49 80 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 MC49_RS17200 4fca851a1d7301e556f27cfc6734b517 493 PIRSF PIRSF006060 1 489 3.2E-81 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MC49_RS06360 3c3ee11bb44e052e2601c9c94e78b770 131 Gene3D G3DSA:3.40.1260.10 4 131 9.2E-30 T 29-03-2018 MC49_RS06360 3c3ee11bb44e052e2601c9c94e78b770 131 Hamap MF_00390 Sulfurtransferase TusD [tusD]. 4 131 36.935 T 29-03-2018 IPR017463 Sulphur relay, TusD/DsrE GO:0005737|GO:0008033|GO:0016783 MC49_RS06360 3c3ee11bb44e052e2601c9c94e78b770 131 Pfam PF02635 DsrE/DsrF-like family 5 131 1.8E-27 T 29-03-2018 IPR003787 Sulphur relay, DsrE/F-like protein MC49_RS06360 3c3ee11bb44e052e2601c9c94e78b770 131 SUPERFAMILY SSF75169 5 131 1.5E-35 T 29-03-2018 IPR027396 DsrEFH-like MC49_RS06360 3c3ee11bb44e052e2601c9c94e78b770 131 TIGRFAM TIGR03012 sulf_tusD_dsrE: sulfur relay protein TusD/DsrE 6 131 2.7E-50 T 29-03-2018 IPR017463 Sulphur relay, TusD/DsrE GO:0005737|GO:0008033|GO:0016783 MC49_RS03655 e2c518a99490ded4f681ca06acd724e9 1120 Pfam PF00924 Mechanosensitive ion channel 886 1084 1.4E-48 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MC49_RS03655 e2c518a99490ded4f681ca06acd724e9 1120 SUPERFAMILY SSF82861 844 927 8.37E-7 T 29-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 MC49_RS03655 e2c518a99490ded4f681ca06acd724e9 1120 SUPERFAMILY SSF82689 996 1091 4.84E-13 T 29-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 MC49_RS03655 e2c518a99490ded4f681ca06acd724e9 1120 Pfam PF12794 Mechanosensitive ion channel inner membrane domain 1 486 825 1.1E-112 T 29-03-2018 IPR025692 Mechanosensitive ion channel inner membrane domain 1 MC49_RS03655 e2c518a99490ded4f681ca06acd724e9 1120 Gene3D G3DSA:1.20.5.110 30 696 6.3E-5 T 29-03-2018 MC49_RS03655 e2c518a99490ded4f681ca06acd724e9 1120 Pfam PF12795 Mechanosensitive ion channel porin domain 34 261 1.3E-54 T 29-03-2018 IPR024393 Mechanosensitive ion channel MscS, porin domain MC49_RS03655 e2c518a99490ded4f681ca06acd724e9 1120 SUPERFAMILY SSF50182 929 994 3.6E-16 T 29-03-2018 IPR010920 LSM domain MC49_RS03655 e2c518a99490ded4f681ca06acd724e9 1120 Gene3D G3DSA:3.30.70.100 996 1090 5.4E-12 T 29-03-2018 MC49_RS03655 e2c518a99490ded4f681ca06acd724e9 1120 Gene3D G3DSA:2.30.30.60 944 993 1.6E-11 T 29-03-2018 MC49_RS13490 6bab6377de7432d4fe70d5b21b3e1ec0 190 Pfam PF03729 Short repeat of unknown function (DUF308) 84 152 2.9E-7 T 29-03-2018 IPR005325 Protein of unknown function DUF308, membrane MC49_RS13490 6bab6377de7432d4fe70d5b21b3e1ec0 190 Pfam PF03729 Short repeat of unknown function (DUF308) 26 97 7.4E-12 T 29-03-2018 IPR005325 Protein of unknown function DUF308, membrane MC49_RS02965 e7801c7fdc18858b34602306cf7a100e 109 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 12 102 5.8E-22 T 29-03-2018 IPR009241 Toxin HigB-like MC49_RS04910 82b896653baabdde792fba6aebde3c85 341 PIRSF PIRSF015268 4 341 2.5E-141 T 29-03-2018 IPR011204 Virulence protein RhuM-like MC49_RS04910 82b896653baabdde792fba6aebde3c85 341 Pfam PF13310 Virulence protein RhuM family 69 319 5.2E-108 T 29-03-2018 IPR011204 Virulence protein RhuM-like MC49_RS00620 ce7cc059d0eb99e99a86b774725d0ace 183 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 11 180 1.4E-72 T 29-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 MC49_RS00620 ce7cc059d0eb99e99a86b774725d0ace 183 Gene3D G3DSA:3.40.50.2020 4 182 1.2E-43 T 29-03-2018 MC49_RS00620 ce7cc059d0eb99e99a86b774725d0ace 183 SUPERFAMILY SSF53271 13 180 1.35E-53 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like MC49_RS00620 ce7cc059d0eb99e99a86b774725d0ace 183 Pfam PF00156 Phosphoribosyl transferase domain 32 156 3.3E-16 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MC49_RS00620 ce7cc059d0eb99e99a86b774725d0ace 183 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 11 180 38.534 T 29-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 MC49_RS06850 8a874d770cf857f0def7cdbe321e3d40 491 TIGRFAM TIGR01539 portal_lambda: phage portal protein, lambda family 31 473 1.6E-141 T 29-03-2018 IPR006429 Phage portal protein, lambda family GO:0005198|GO:0019068 MC49_RS06850 8a874d770cf857f0def7cdbe321e3d40 491 Pfam PF05136 Phage portal protein, lambda family 36 367 4.7E-83 T 29-03-2018 IPR006429 Phage portal protein, lambda family GO:0005198|GO:0019068 MC49_RS02125 ca26c99e153153ac6e4e0cdc31070f05 97 Hamap MF_00580 10 kDa chaperonin [groS]. 2 96 23.7 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MC49_RS02125 ca26c99e153153ac6e4e0cdc31070f05 97 Pfam PF00166 Chaperonin 10 Kd subunit 2 95 2.0E-29 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MC49_RS02125 ca26c99e153153ac6e4e0cdc31070f05 97 Gene3D G3DSA:2.30.33.40 1 96 8.0E-33 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MC49_RS02125 ca26c99e153153ac6e4e0cdc31070f05 97 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 29-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 MC49_RS02125 ca26c99e153153ac6e4e0cdc31070f05 97 SMART SM00883 2 95 1.6E-47 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MC49_RS02125 ca26c99e153153ac6e4e0cdc31070f05 97 SUPERFAMILY SSF50129 1 96 2.54E-31 T 29-03-2018 IPR011032 GroES-like MC49_RS02125 ca26c99e153153ac6e4e0cdc31070f05 97 PRINTS PR00297 10kDa chaperonin signature 25 46 2.1E-27 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MC49_RS02125 ca26c99e153153ac6e4e0cdc31070f05 97 PRINTS PR00297 10kDa chaperonin signature 3 18 2.1E-27 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MC49_RS02125 ca26c99e153153ac6e4e0cdc31070f05 97 PRINTS PR00297 10kDa chaperonin signature 60 72 2.1E-27 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MC49_RS02125 ca26c99e153153ac6e4e0cdc31070f05 97 PRINTS PR00297 10kDa chaperonin signature 82 95 2.1E-27 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MC49_RS15015 05dc2a24e8b6fb29cb1a6310198b18f2 346 SUPERFAMILY SSF51735 3 157 3.95E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS15015 05dc2a24e8b6fb29cb1a6310198b18f2 346 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 134 241 4.2E-15 T 29-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 MC49_RS15015 05dc2a24e8b6fb29cb1a6310198b18f2 346 SUPERFAMILY SSF55347 129 313 1.16E-29 T 29-03-2018 MC49_RS15015 05dc2a24e8b6fb29cb1a6310198b18f2 346 Gene3D G3DSA:3.30.360.10 135 346 5.3E-46 T 29-03-2018 MC49_RS15015 05dc2a24e8b6fb29cb1a6310198b18f2 346 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 122 3.6E-24 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 MC49_RS15015 05dc2a24e8b6fb29cb1a6310198b18f2 346 Gene3D G3DSA:3.40.50.720 1 134 5.7E-37 T 29-03-2018 MC49_RS05540 62c9ebd93e0a236e402c1d89ffd93d0e 404 Pfam PF02441 Flavoprotein 7 180 3.5E-41 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 MC49_RS05540 62c9ebd93e0a236e402c1d89ffd93d0e 404 Gene3D G3DSA:3.40.50.1950 1 184 6.2E-53 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 MC49_RS05540 62c9ebd93e0a236e402c1d89ffd93d0e 404 SUPERFAMILY SSF102645 185 400 1.22E-79 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 MC49_RS05540 62c9ebd93e0a236e402c1d89ffd93d0e 404 SUPERFAMILY SSF52507 1 181 1.57E-54 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 MC49_RS05540 62c9ebd93e0a236e402c1d89ffd93d0e 404 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 188 369 8.0E-73 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 MC49_RS05540 62c9ebd93e0a236e402c1d89ffd93d0e 404 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 5 394 1.3E-153 T 29-03-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 MC49_RS05540 62c9ebd93e0a236e402c1d89ffd93d0e 404 Gene3D G3DSA:3.40.50.10300 185 403 3.6E-68 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 MC49_RS10115 a5ae5064e815f8423cec5279da400f3b 156 SUPERFAMILY SSF75217 1 154 1.78E-49 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases MC49_RS10115 a5ae5064e815f8423cec5279da400f3b 156 PIRSF PIRSF004505 1 155 5.4E-41 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MC49_RS10115 a5ae5064e815f8423cec5279da400f3b 156 Gene3D G3DSA:3.40.1280.10 1 155 1.2E-49 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MC49_RS10115 a5ae5064e815f8423cec5279da400f3b 156 Pfam PF02590 Predicted SPOUT methyltransferase 1 154 8.1E-47 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MC49_RS10115 a5ae5064e815f8423cec5279da400f3b 156 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 155 26.489 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MC49_RS10115 a5ae5064e815f8423cec5279da400f3b 156 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 2 156 8.5E-79 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 MC49_RS01100 0cecad0a2b0892338299fa16de057634 314 Gene3D G3DSA:3.40.190.10 88 174 1.2E-15 T 29-03-2018 MC49_RS01100 0cecad0a2b0892338299fa16de057634 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.8E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS01100 0cecad0a2b0892338299fa16de057634 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.8E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS01100 0cecad0a2b0892338299fa16de057634 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.8E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS01100 0cecad0a2b0892338299fa16de057634 314 Gene3D G3DSA:1.10.10.10 1 83 9.3E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS01100 0cecad0a2b0892338299fa16de057634 314 Pfam PF03466 LysR substrate binding domain 87 289 1.9E-30 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS01100 0cecad0a2b0892338299fa16de057634 314 Gene3D G3DSA:3.40.190.10 175 265 3.5E-16 T 29-03-2018 MC49_RS01100 0cecad0a2b0892338299fa16de057634 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.3E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS01100 0cecad0a2b0892338299fa16de057634 314 SUPERFAMILY SSF53850 91 285 2.33E-28 T 29-03-2018 MC49_RS01100 0cecad0a2b0892338299fa16de057634 314 SUPERFAMILY SSF46785 1 87 1.5E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS01125 330e3cecc58f3976dcd17c52be331fc5 111 Pfam PF00893 Small Multidrug Resistance protein 8 101 3.1E-20 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 MC49_RS01125 330e3cecc58f3976dcd17c52be331fc5 111 SUPERFAMILY SSF103481 11 110 3.79E-14 T 29-03-2018 MC49_RS02860 a549b08d0ec4a25fd0b5ed91b9470cc7 156 Gene3D G3DSA:2.160.20.70 8 112 6.3E-4 T 29-03-2018 MC49_RS02860 a549b08d0ec4a25fd0b5ed91b9470cc7 156 Pfam PF04519 Polymer-forming cytoskeletal 36 132 3.2E-18 T 29-03-2018 IPR007607 Protein of unknown function DUF583 MC49_RS16745 50e3798f4554df1a17ddb106fbe118fa 446 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 18 446 7.9E-132 T 29-03-2018 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) MC49_RS16745 50e3798f4554df1a17ddb106fbe118fa 446 Gene3D G3DSA:2.40.160.60 26 446 2.0E-82 T 29-03-2018 MC49_RS16745 50e3798f4554df1a17ddb106fbe118fa 446 SUPERFAMILY SSF56935 26 446 2.84E-105 T 29-03-2018 MC49_RS14570 08ed1cff7e45c2c339174e4c7f0a2f97 201 SUPERFAMILY SSF144091 26 197 1.57E-24 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 MC49_RS14570 08ed1cff7e45c2c339174e4c7f0a2f97 201 Pfam PF01694 Rhomboid family 58 194 7.2E-19 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 MC49_RS14570 08ed1cff7e45c2c339174e4c7f0a2f97 201 Gene3D G3DSA:1.20.1540.10 22 193 2.8E-15 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 MC49_RS18040 e7dd4c7085d959f6736a21d772eeee64 144 Pfam PF00582 Universal stress protein family 1 144 1.8E-19 T 29-03-2018 IPR006016 UspA GO:0006950 MC49_RS18040 e7dd4c7085d959f6736a21d772eeee64 144 SUPERFAMILY SSF52402 2 144 1.67E-26 T 29-03-2018 MC49_RS18040 e7dd4c7085d959f6736a21d772eeee64 144 PRINTS PR01438 Universal stress protein signature 122 144 1.6E-10 T 29-03-2018 IPR006015 Universal stress protein A MC49_RS18040 e7dd4c7085d959f6736a21d772eeee64 144 PRINTS PR01438 Universal stress protein signature 2 20 1.6E-10 T 29-03-2018 IPR006015 Universal stress protein A MC49_RS18040 e7dd4c7085d959f6736a21d772eeee64 144 PRINTS PR01438 Universal stress protein signature 105 117 1.6E-10 T 29-03-2018 IPR006015 Universal stress protein A MC49_RS18040 e7dd4c7085d959f6736a21d772eeee64 144 Gene3D G3DSA:3.40.50.620 2 144 7.7E-27 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS13660 e510b5e2ef8d435c8652506c2403c4c1 127 ProDom PD077599 YEBF LIPOPROTEIN EXPORTED PERIPLASMIC PRECURSOR SIGNAL SIMILAR PALMITATE MEMBRANE ESCHERICHIA 37 123 6.0E-20 T 29-03-2018 IPR025603 YebF/Colicin-M immunity protein MC49_RS13660 e510b5e2ef8d435c8652506c2403c4c1 127 Pfam PF13995 YebF-like protein 37 124 2.2E-37 T 29-03-2018 IPR025603 YebF/Colicin-M immunity protein MC49_RS13570 0642c0acf42802ea80cd6b4c362b85ad 622 SUPERFAMILY SSF51338 496 543 7.97E-20 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS13570 0642c0acf42802ea80cd6b4c362b85ad 622 SUPERFAMILY SSF51338 5 65 7.97E-20 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS13570 0642c0acf42802ea80cd6b4c362b85ad 622 Gene3D G3DSA:3.20.20.140 74 490 6.2E-35 T 29-03-2018 MC49_RS13570 0642c0acf42802ea80cd6b4c362b85ad 622 SUPERFAMILY SSF51556 64 126 7.15E-43 T 29-03-2018 IPR032466 Metal-dependent hydrolase MC49_RS13570 0642c0acf42802ea80cd6b4c362b85ad 622 SUPERFAMILY SSF51556 206 496 7.15E-43 T 29-03-2018 IPR032466 Metal-dependent hydrolase MC49_RS13570 0642c0acf42802ea80cd6b4c362b85ad 622 Gene3D G3DSA:2.30.40.10 5 73 2.1E-18 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS13570 0642c0acf42802ea80cd6b4c362b85ad 622 Pfam PF07969 Amidohydrolase family 53 537 7.9E-118 T 29-03-2018 IPR013108 Amidohydrolase 3 MC49_RS17505 abd8a54634643e3e7278332af39f01b8 171 Pfam PF04985 Phage tail tube protein FII 4 170 2.5E-64 T 29-03-2018 IPR006498 Tail tube protein MC49_RS17505 abd8a54634643e3e7278332af39f01b8 171 TIGRFAM TIGR01611 tail_tube: phage major tail tube protein 3 171 1.4E-53 T 29-03-2018 IPR006498 Tail tube protein MC49_RS14380 646b1743a7da3acfeb860753b2427a65 463 SUPERFAMILY SSF52467 290 463 1.44E-79 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MC49_RS14380 646b1743a7da3acfeb860753b2427a65 463 PIRSF PIRSF000204 1 463 3.9E-237 T 29-03-2018 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 MC49_RS14380 646b1743a7da3acfeb860753b2427a65 463 Gene3D G3DSA:3.40.50.1220 290 463 1.4E-92 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MC49_RS14380 646b1743a7da3acfeb860753b2427a65 463 Pfam PF02233 NAD(P) transhydrogenase beta subunit 7 461 8.5E-207 T 29-03-2018 IPR034300 NADP transhydrogenase beta-like domain KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 MC49_RS08610 14898aab3dda4af234ee3968ed543c14 297 PIRSF PIRSF018982 48 297 3.6E-99 T 29-03-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 MC49_RS08610 14898aab3dda4af234ee3968ed543c14 297 PIRSF PIRSF018982 3 46 280.0 T 29-03-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 MC49_RS08610 14898aab3dda4af234ee3968ed543c14 297 Hamap MF_00601 Ethanolamine ammonia-lyase light chain [eutC]. 59 296 38.747 T 29-03-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 MC49_RS08610 14898aab3dda4af234ee3968ed543c14 297 Pfam PF05985 Ethanolamine ammonia-lyase light chain (EutC) 68 295 4.1E-77 T 29-03-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 MC49_RS10335 65112fa941b6acfe8cd32f7ee44493ea 247 SUPERFAMILY SSF102705 1 246 8.76E-80 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 MC49_RS10335 65112fa941b6acfe8cd32f7ee44493ea 247 Gene3D G3DSA:3.40.1390.30 1 109 9.3E-27 T 29-03-2018 MC49_RS10335 65112fa941b6acfe8cd32f7ee44493ea 247 Gene3D G3DSA:3.40.1390.30 110 218 3.7E-30 T 29-03-2018 MC49_RS10335 65112fa941b6acfe8cd32f7ee44493ea 247 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 6 233 5.9E-57 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 MC49_RS10335 65112fa941b6acfe8cd32f7ee44493ea 247 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 1 246 2.8E-68 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 MC49_RS04995 b5fd282efe2f98e304d6d4bc9ce13276 222 Gene3D G3DSA:1.10.10.60 76 169 4.9E-8 T 29-03-2018 MC49_RS04995 b5fd282efe2f98e304d6d4bc9ce13276 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 44 89 3.4E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS04995 b5fd282efe2f98e304d6d4bc9ce13276 222 SUPERFAMILY SSF46689 32 100 4.98E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS04995 b5fd282efe2f98e304d6d4bc9ce13276 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 56 1.2E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS04995 b5fd282efe2f98e304d6d4bc9ce13276 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 64 87 1.2E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS04995 b5fd282efe2f98e304d6d4bc9ce13276 222 Gene3D G3DSA:1.10.10.60 25 75 2.2E-13 T 29-03-2018 MC49_RS04995 b5fd282efe2f98e304d6d4bc9ce13276 222 ProSitePatterns PS01081 TetR-type HTH domain signature. 55 86 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MC49_RS10410 424ca171e41e253cb9c1ade6a9d9a283 35 TIGRFAM TIGR02106 cyd_oper_ybgT: cyd operon protein YbgT 1 29 2.8E-18 T 29-03-2018 IPR011724 Cyd operon protein YbgT MetaCyc: PWY-7545 MC49_RS10410 424ca171e41e253cb9c1ade6a9d9a283 35 Pfam PF08173 Membrane bound YbgT-like protein 1 26 1.9E-14 T 29-03-2018 IPR012994 Membrane bound YbgT-like MC49_RS15010 702df8f8a344d577d0f304d5fb4b26d9 329 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 11 321 2.9E-102 T 29-03-2018 IPR016833 Putative sodium bile acid cotransporter MC49_RS15010 702df8f8a344d577d0f304d5fb4b26d9 329 PIRSF PIRSF026166 1 329 7.1E-129 T 29-03-2018 IPR016833 Putative sodium bile acid cotransporter MC49_RS03400 d0917e6166e8e3ec0399127a3eed5134 112 Pfam PF03840 Preprotein translocase SecG subunit 5 72 3.6E-22 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MC49_RS03400 d0917e6166e8e3ec0399127a3eed5134 112 PRINTS PR01651 Protein-export SecG membrane protein signature 54 76 2.4E-42 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MC49_RS03400 d0917e6166e8e3ec0399127a3eed5134 112 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 2.4E-42 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MC49_RS03400 d0917e6166e8e3ec0399127a3eed5134 112 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 2.4E-42 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MC49_RS03400 d0917e6166e8e3ec0399127a3eed5134 112 PRINTS PR01651 Protein-export SecG membrane protein signature 38 54 2.4E-42 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MC49_RS03400 d0917e6166e8e3ec0399127a3eed5134 112 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 2 73 7.5E-27 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MC49_RS18720 39904d98a305c1a133718a3ecdfe65ee 602 Gene3D G3DSA:3.30.300.30 466 602 1.1E-14 T 29-03-2018 MC49_RS18720 39904d98a305c1a133718a3ecdfe65ee 602 SUPERFAMILY SSF56801 7 290 4.97E-115 T 29-03-2018 MC49_RS18720 39904d98a305c1a133718a3ecdfe65ee 602 SUPERFAMILY SSF56801 341 600 4.97E-115 T 29-03-2018 MC49_RS18720 39904d98a305c1a133718a3ecdfe65ee 602 Pfam PF00501 AMP-binding enzyme 16 471 7.7E-94 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 MC49_RS18720 39904d98a305c1a133718a3ecdfe65ee 602 Gene3D G3DSA:3.40.50.980 194 390 1.5E-39 T 29-03-2018 MC49_RS18720 39904d98a305c1a133718a3ecdfe65ee 602 Gene3D G3DSA:2.30.38.10 391 464 4.1E-21 T 29-03-2018 MC49_RS18720 39904d98a305c1a133718a3ecdfe65ee 602 Gene3D G3DSA:3.40.50.980 9 193 6.8E-35 T 29-03-2018 MC49_RS18720 39904d98a305c1a133718a3ecdfe65ee 602 ProSitePatterns PS00455 Putative AMP-binding domain signature. 188 199 - T 29-03-2018 IPR020845 AMP-binding, conserved site MC49_RS16380 a62a70a29d4553d23b0e4794bd609d27 268 ProSitePatterns PS01228 Hypothetical cof family signature 1. 5 16 - T 29-03-2018 MC49_RS16380 a62a70a29d4553d23b0e4794bd609d27 268 Gene3D G3DSA:3.40.50.1000 1 268 6.9E-47 T 29-03-2018 IPR023214 HAD-like domain MC49_RS16380 a62a70a29d4553d23b0e4794bd609d27 268 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 237 3.0E-28 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 MC49_RS16380 a62a70a29d4553d23b0e4794bd609d27 268 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 264 2.3E-63 T 29-03-2018 IPR023214 HAD-like domain MC49_RS16380 a62a70a29d4553d23b0e4794bd609d27 268 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 264 2.6E-65 T 29-03-2018 IPR000150 Cof family GO:0016787 MC49_RS16380 a62a70a29d4553d23b0e4794bd609d27 268 SUPERFAMILY SSF56784 1 268 3.76E-73 T 29-03-2018 IPR023214 HAD-like domain MC49_RS16380 a62a70a29d4553d23b0e4794bd609d27 268 ProSitePatterns PS01229 Hypothetical cof family signature 2. 218 240 - T 29-03-2018 MC49_RS05680 676189398d9ff1fddcd039d5b71ff423 184 Pfam PF02397 Bacterial sugar transferase 2 179 4.4E-68 T 29-03-2018 IPR003362 Bacterial sugar transferase MC49_RS12020 0fa06a7020510a2607fd033b269484b3 479 SUPERFAMILY SSF53850 51 265 1.27E-35 T 29-03-2018 MC49_RS12020 0fa06a7020510a2607fd033b269484b3 479 SMART SM00062 43 267 2.4E-36 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MC49_RS12020 0fa06a7020510a2607fd033b269484b3 479 Pfam PF01464 Transglycosylase SLT domain 297 396 6.6E-21 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 MC49_RS12020 0fa06a7020510a2607fd033b269484b3 479 Gene3D G3DSA:3.40.190.10 163 271 3.9E-7 T 29-03-2018 MC49_RS12020 0fa06a7020510a2607fd033b269484b3 479 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 308 336 - T 29-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 MC49_RS12020 0fa06a7020510a2607fd033b269484b3 479 SUPERFAMILY SSF53955 243 396 1.06E-35 T 29-03-2018 IPR023346 Lysozyme-like domain MC49_RS12020 0fa06a7020510a2607fd033b269484b3 479 SUPERFAMILY SSF53955 431 446 1.06E-35 T 29-03-2018 IPR023346 Lysozyme-like domain MC49_RS12020 0fa06a7020510a2607fd033b269484b3 479 Gene3D G3DSA:3.40.190.10 1 162 4.1E-17 T 29-03-2018 MC49_RS12020 0fa06a7020510a2607fd033b269484b3 479 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 50 265 1.5E-32 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MC49_RS12020 0fa06a7020510a2607fd033b269484b3 479 Hamap MF_02016 Membrane-bound lytic murein transglycosylase F [mltF]. 5 473 45.006 T 29-03-2018 IPR023703 Membrane-bound lytic murein transglycosylase F GO:0016837 MC49_RS12020 0fa06a7020510a2607fd033b269484b3 479 Gene3D G3DSA:1.10.530.10 272 449 8.8E-35 T 29-03-2018 MC49_RS17160 c7669713513ebed53c5040b5f5f63130 581 Gene3D G3DSA:3.30.465.10 107 268 6.9E-77 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 MC49_RS17160 c7669713513ebed53c5040b5f5f63130 581 Gene3D G3DSA:3.30.43.10 3 103 1.6E-10 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 MC49_RS17160 c7669713513ebed53c5040b5f5f63130 581 SUPERFAMILY SSF55103 276 567 6.32E-115 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 MC49_RS17160 c7669713513ebed53c5040b5f5f63130 581 Gene3D G3DSA:3.30.70.610 349 434 1.0E-29 T 29-03-2018 IPR016172 D-lactate dehydrogenase, C-terminal subdomain 1 GO:0006089|GO:0050660|GO:0055085 KEGG: 00620+1.1.1.28|MetaCyc: PWY-6454|MetaCyc: PWY-6901 MC49_RS17160 c7669713513ebed53c5040b5f5f63130 581 Gene3D G3DSA:3.30.70.610 269 348 3.0E-18 T 29-03-2018 IPR016172 D-lactate dehydrogenase, C-terminal subdomain 1 GO:0006089|GO:0050660|GO:0055085 KEGG: 00620+1.1.1.28|MetaCyc: PWY-6454|MetaCyc: PWY-6901 MC49_RS17160 c7669713513ebed53c5040b5f5f63130 581 PIRSF PIRSF000101 4 569 1.3E-284 T 29-03-2018 IPR012256 D-lactate dehydrogenase GO:0004457|GO:0005887|GO:0006089|GO:0050660|GO:0051287 KEGG: 00620+1.1.1.28|MetaCyc: PWY-6454|MetaCyc: PWY-6901 MC49_RS17160 c7669713513ebed53c5040b5f5f63130 581 Pfam PF01565 FAD binding domain 47 184 2.9E-7 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MC49_RS17160 c7669713513ebed53c5040b5f5f63130 581 Pfam PF09330 D-lactate dehydrogenase, membrane binding 278 567 1.4E-146 T 29-03-2018 IPR015409 D-lactate dehydrogenase, membrane binding, C-terminal GO:0050660|GO:0055085 KEGG: 00620+1.1.1.28|MetaCyc: PWY-6454|MetaCyc: PWY-6901 MC49_RS17160 c7669713513ebed53c5040b5f5f63130 581 SUPERFAMILY SSF56176 11 271 3.33E-69 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 MC49_RS17160 c7669713513ebed53c5040b5f5f63130 581 Gene3D G3DSA:3.30.1370.20 435 518 7.3E-42 T 29-03-2018 IPR016173 D-lactate dehydrogenase, C-terminal subdomain 2 GO:0006089|GO:0050660|GO:0055085 KEGG: 00620+1.1.1.28|MetaCyc: PWY-6454|MetaCyc: PWY-6901 MC49_RS04640 f100d15bab78b37ecfc4034bddb32780 228 Pfam PF03475 3-alpha domain 169 212 1.5E-12 T 29-03-2018 IPR005163 3-alpha domain MC49_RS04640 f100d15bab78b37ecfc4034bddb32780 228 Pfam PF03473 MOSC domain 48 159 4.1E-17 T 29-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 MC49_RS04640 f100d15bab78b37ecfc4034bddb32780 228 Gene3D G3DSA:2.40.33.20 2 228 4.4E-41 T 29-03-2018 MC49_RS04640 f100d15bab78b37ecfc4034bddb32780 228 SUPERFAMILY SSF50800 4 224 2.88E-68 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain MC49_RS09720 ff8ff27b04799f73afdac7df96ecf536 209 Hamap MF_00428 Na(+)-translocating NADH-quinone reductase subunit D [nqrD]. 2 207 36.361 T 29-03-2018 IPR011292 Na(+)-translocating NADH-quinone reductase subunit D GO:0016655|GO:0055114 MC49_RS09720 ff8ff27b04799f73afdac7df96ecf536 209 TIGRFAM TIGR01939 nqrD: NADH:ubiquinone oxidoreductase, Na(+)-translocating, D subunit 4 207 1.2E-102 T 29-03-2018 IPR011292 Na(+)-translocating NADH-quinone reductase subunit D GO:0016655|GO:0055114 MC49_RS09720 ff8ff27b04799f73afdac7df96ecf536 209 PIRSF PIRSF006102 3 209 1.1E-68 T 29-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 MC49_RS09720 ff8ff27b04799f73afdac7df96ecf536 209 Pfam PF02508 Rnf-Nqr subunit, membrane protein 9 195 5.0E-60 T 29-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 MC49_RS09655 5ef5a80f921ef98a938b627e0b85e045 292 Gene3D G3DSA:3.60.15.10 19 261 3.1E-22 T 29-03-2018 IPR001279 Metallo-beta-lactamase MC49_RS09655 5ef5a80f921ef98a938b627e0b85e045 292 SUPERFAMILY SSF56281 24 245 2.8E-37 T 29-03-2018 IPR001279 Metallo-beta-lactamase MC49_RS09655 5ef5a80f921ef98a938b627e0b85e045 292 Pfam PF00753 Metallo-beta-lactamase superfamily 41 225 1.5E-9 T 29-03-2018 IPR001279 Metallo-beta-lactamase MC49_RS09655 5ef5a80f921ef98a938b627e0b85e045 292 SMART SM00849 40 225 1.2E-18 T 29-03-2018 IPR001279 Metallo-beta-lactamase MC49_RS16270 e87f11f4e5be0560f33fadeb26060832 449 Gene3D G3DSA:1.20.1250.20 231 449 1.9E-15 T 29-03-2018 MC49_RS16270 e87f11f4e5be0560f33fadeb26060832 449 Pfam PF07690 Major Facilitator Superfamily 68 394 1.5E-22 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS16270 e87f11f4e5be0560f33fadeb26060832 449 Gene3D G3DSA:1.20.1250.20 13 230 6.0E-24 T 29-03-2018 MC49_RS16270 e87f11f4e5be0560f33fadeb26060832 449 SUPERFAMILY SSF103473 18 430 8.89E-57 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS05855 b818956d0e736fb87f73998c47ed6d9c 309 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 11 304 21.079 T 29-03-2018 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 MC49_RS05855 b818956d0e736fb87f73998c47ed6d9c 309 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 20 303 2.7E-118 T 29-03-2018 MC49_RS05855 b818956d0e736fb87f73998c47ed6d9c 309 Pfam PF01040 UbiA prenyltransferase family 29 271 5.8E-35 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 MC49_RS05855 b818956d0e736fb87f73998c47ed6d9c 309 PIRSF PIRSF005355 4 309 4.1E-89 T 29-03-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 MC49_RS10290 37da7dd09b4ce92bdef3690085a89d01 149 SUPERFAMILY SSF46785 5 135 1.68E-44 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS10290 37da7dd09b4ce92bdef3690085a89d01 149 Pfam PF01475 Ferric uptake regulator family 11 130 3.2E-47 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 MC49_RS10290 37da7dd09b4ce92bdef3690085a89d01 149 Gene3D G3DSA:1.10.10.10 4 88 2.0E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS12645 6f55dfd04e3dce34932cf8690c81c807 103 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 4 103 18.406 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 MC49_RS12645 6f55dfd04e3dce34932cf8690c81c807 103 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 32 48 2.8E-17 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 MC49_RS12645 6f55dfd04e3dce34932cf8690c81c807 103 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 67 83 2.8E-17 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 MC49_RS12645 6f55dfd04e3dce34932cf8690c81c807 103 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 88 101 2.8E-17 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 MC49_RS12645 6f55dfd04e3dce34932cf8690c81c807 103 Pfam PF02049 Flagellar hook-basal body complex protein FliE 17 103 3.5E-28 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 MC49_RS12645 6f55dfd04e3dce34932cf8690c81c807 103 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 2 102 3.6E-30 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 MC49_RS02610 669e91fd408302c841e5c6a1dda9304c 180 SUPERFAMILY SSF52540 5 173 1.78E-23 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS02610 669e91fd408302c841e5c6a1dda9304c 180 Pfam PF01202 Shikimate kinase 17 126 5.4E-11 T 29-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 MC49_RS02610 669e91fd408302c841e5c6a1dda9304c 180 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 11 172 4.1E-63 T 29-03-2018 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 MC49_RS02610 669e91fd408302c841e5c6a1dda9304c 180 Gene3D G3DSA:3.40.50.300 7 179 6.5E-25 T 29-03-2018 MC49_RS07450 13f11110140feb24867425f593aea7a8 325 SUPERFAMILY SSF56784 112 316 1.29E-48 T 29-03-2018 IPR023214 HAD-like domain MC49_RS07450 13f11110140feb24867425f593aea7a8 325 Pfam PF12710 haloacid dehalogenase-like hydrolase 149 282 3.0E-17 T 29-03-2018 MC49_RS07450 13f11110140feb24867425f593aea7a8 325 Gene3D G3DSA:1.10.150.210 136 170 6.8E-25 T 29-03-2018 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 MC49_RS07450 13f11110140feb24867425f593aea7a8 325 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 114 284 4.4E-25 T 29-03-2018 MC49_RS07450 13f11110140feb24867425f593aea7a8 325 Gene3D G3DSA:3.40.50.1000 171 316 1.1E-27 T 29-03-2018 IPR023214 HAD-like domain MC49_RS07450 13f11110140feb24867425f593aea7a8 325 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 98 316 1.9E-85 T 29-03-2018 MC49_RS07450 13f11110140feb24867425f593aea7a8 325 Gene3D G3DSA:3.30.70.260 51 135 5.9E-4 T 29-03-2018 MC49_RS01200 eddfa21e34449f50c60550cabd76d320 98 SMART SM00530 28 83 4.0E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS01200 eddfa21e34449f50c60550cabd76d320 98 Gene3D G3DSA:1.10.260.40 15 90 8.7E-18 T 29-03-2018 MC49_RS01200 eddfa21e34449f50c60550cabd76d320 98 SUPERFAMILY SSF47413 22 88 9.29E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS01200 eddfa21e34449f50c60550cabd76d320 98 Pfam PF01381 Helix-turn-helix 29 82 3.3E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS12090 c1af3725b3b505c6a9b400be83cd99e8 383 Gene3D G3DSA:1.20.1250.20 193 383 9.6E-13 T 29-03-2018 MC49_RS12090 c1af3725b3b505c6a9b400be83cd99e8 383 Gene3D G3DSA:1.20.1250.20 2 189 4.8E-10 T 29-03-2018 MC49_RS12090 c1af3725b3b505c6a9b400be83cd99e8 383 SUPERFAMILY SSF103473 7 379 1.57E-34 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS12090 c1af3725b3b505c6a9b400be83cd99e8 383 PIRSF PIRSF004925 1 383 1.6E-107 T 29-03-2018 IPR026032 Probable 3-phenylpropionic acid transporter MC49_RS12090 c1af3725b3b505c6a9b400be83cd99e8 383 Pfam PF12832 MFS_1 like family 8 357 1.0E-45 T 29-03-2018 IPR024989 Major facilitator superfamily associated domain MC49_RS02920 495ba1ff30ffbd4fab90476cb00ae3d6 460 Gene3D G3DSA:1.20.1250.20 14 235 4.9E-16 T 29-03-2018 MC49_RS02920 495ba1ff30ffbd4fab90476cb00ae3d6 460 Gene3D G3DSA:1.20.1250.20 243 460 4.3E-25 T 29-03-2018 MC49_RS02920 495ba1ff30ffbd4fab90476cb00ae3d6 460 TIGRFAM TIGR00886 2A0108: nitrite transporter 35 417 4.6E-112 T 29-03-2018 IPR004737 Nitrate transporter GO:0015112|GO:0015113|GO:0015706|GO:0015707|GO:0016021 MC49_RS02920 495ba1ff30ffbd4fab90476cb00ae3d6 460 SUPERFAMILY SSF103473 34 459 1.96E-39 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS02920 495ba1ff30ffbd4fab90476cb00ae3d6 460 Pfam PF07690 Major Facilitator Superfamily 44 339 8.7E-15 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS18085 a1857e78bf5c353cb33bef586bf13852 384 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 177 372 6.8E-19 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain MC49_RS18085 a1857e78bf5c353cb33bef586bf13852 384 SUPERFAMILY SSF52266 171 380 2.33E-38 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain MC49_RS18085 a1857e78bf5c353cb33bef586bf13852 384 Gene3D G3DSA:3.40.50.1110 163 377 6.1E-25 T 29-03-2018 MC49_RS01140 0db2da3e0c5a436cdb8ad5978d7f0cad 660 Pfam PF11843 Protein of unknown function (DUF3363) 286 657 5.1E-140 T 29-03-2018 IPR021795 Protein of unknown function DUF3363 MC49_RS08415 f3734c0b9d87265575a2acec3d1a39ab 241 SUPERFAMILY SSF53790 1 239 1.7E-57 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MC49_RS08415 f3734c0b9d87265575a2acec3d1a39ab 241 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 2 240 1.1E-104 T 29-03-2018 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 MC49_RS08415 f3734c0b9d87265575a2acec3d1a39ab 241 Gene3D G3DSA:3.30.950.10 121 238 1.6E-51 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MC49_RS08415 f3734c0b9d87265575a2acec3d1a39ab 241 Gene3D G3DSA:3.40.1010.10 1 120 5.4E-35 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MC49_RS08415 f3734c0b9d87265575a2acec3d1a39ab 241 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 1 208 6.8E-41 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 MC49_RS09880 63996e17beecaf7ee24f02f8b76cb42b 182 Gene3D G3DSA:2.40.30.60 12 100 5.6E-25 T 29-03-2018 IPR002676 RimM protein GO:0006364 MC49_RS09880 63996e17beecaf7ee24f02f8b76cb42b 182 Pfam PF05239 PRC-barrel domain 104 168 9.1E-9 T 29-03-2018 IPR027275 PRC-barrel domain MC49_RS09880 63996e17beecaf7ee24f02f8b76cb42b 182 SUPERFAMILY SSF50447 12 100 2.51E-24 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain MC49_RS09880 63996e17beecaf7ee24f02f8b76cb42b 182 Pfam PF01782 RimM N-terminal domain 16 96 1.7E-24 T 29-03-2018 IPR002676 RimM protein GO:0006364 MC49_RS09880 63996e17beecaf7ee24f02f8b76cb42b 182 Gene3D G3DSA:2.30.30.240 102 177 9.0E-22 T 29-03-2018 MC49_RS09880 63996e17beecaf7ee24f02f8b76cb42b 182 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 14 182 5.1E-59 T 29-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 MC49_RS09880 63996e17beecaf7ee24f02f8b76cb42b 182 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 13 182 24.329 T 29-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 MC49_RS09880 63996e17beecaf7ee24f02f8b76cb42b 182 SUPERFAMILY SSF50346 106 182 1.02E-19 T 29-03-2018 IPR011033 PRC-barrel-like MC49_RS14465 8a46f84adc09afb58452c8c986c61b28 294 SUPERFAMILY SSF103481 55 139 1.15E-6 T 29-03-2018 MC49_RS14465 8a46f84adc09afb58452c8c986c61b28 294 Pfam PF00892 EamA-like transporter family 155 286 4.2E-14 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MC49_RS14465 8a46f84adc09afb58452c8c986c61b28 294 Pfam PF00892 EamA-like transporter family 13 141 2.1E-12 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MC49_RS14465 8a46f84adc09afb58452c8c986c61b28 294 SUPERFAMILY SSF103481 190 292 3.92E-9 T 29-03-2018 MC49_RS18305 8a05a25f53413875ca79f0d8732781bd 246 SUPERFAMILY SSF102198 14 244 1.7E-51 T 29-03-2018 MC49_RS18305 8a05a25f53413875ca79f0d8732781bd 246 Gene3D G3DSA:3.50.30.50 13 246 1.4E-46 T 29-03-2018 MC49_RS18305 8a05a25f53413875ca79f0d8732781bd 246 Pfam PF04199 Putative cyclase 18 182 7.8E-31 T 29-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 MC49_RS04895 881d95f905568b37b5bc25ae98f4c793 146 ProDom PD012854 PLASMID KLCA ANTIRESTRICTION YFJX YCIB ARDB STABLE YFEB Z1216 C0275 52 146 6.0E-22 T 29-03-2018 IPR004914 Antirestriction protein MC49_RS04895 881d95f905568b37b5bc25ae98f4c793 146 Pfam PF03230 Antirestriction protein 56 146 2.5E-29 T 29-03-2018 IPR004914 Antirestriction protein MC49_RS15090 4a2968dba5cf2b58e75dd5bec05197ac 206 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 9 198 1.4E-90 T 29-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 MC49_RS15090 4a2968dba5cf2b58e75dd5bec05197ac 206 Pfam PF00925 GTP cyclohydrolase II 9 174 1.3E-66 T 29-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 MC49_RS15090 4a2968dba5cf2b58e75dd5bec05197ac 206 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 5 200 47.281 T 29-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 MC49_RS15090 4a2968dba5cf2b58e75dd5bec05197ac 206 SUPERFAMILY SSF142695 7 177 3.01E-65 T 29-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 MC49_RS07670 eb1e8cf452ed698e71c0e90ab543454c 140 TIGRFAM TIGR02803 ExbD_1: TonB system transport protein ExbD 16 136 2.8E-65 T 29-03-2018 IPR014170 TonB system transport protein ExbD type-1 GO:0006810|GO:0016020 MC49_RS07670 eb1e8cf452ed698e71c0e90ab543454c 140 Pfam PF02472 Biopolymer transport protein ExbD/TolR 14 133 2.9E-29 T 29-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 MC49_RS03715 45b722dddc69ab401c03da638fd3e025 236 Gene3D G3DSA:3.30.450.40 50 232 5.5E-4 T 29-03-2018 IPR029016 GAF domain-like MC49_RS03715 45b722dddc69ab401c03da638fd3e025 236 Pfam PF04340 Protein of unknown function, DUF484 17 233 3.5E-63 T 29-03-2018 IPR007435 Protein of unknown function DUF484 MC49_RS09340 2f21d4da30ca0bb3aec26de8b2e8c408 490 Pfam PF00171 Aldehyde dehydrogenase family 24 483 2.5E-170 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 MC49_RS09340 2f21d4da30ca0bb3aec26de8b2e8c408 490 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 35 482 1.4E-219 T 29-03-2018 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 MC49_RS09340 2f21d4da30ca0bb3aec26de8b2e8c408 490 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 288 299 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 MC49_RS09340 2f21d4da30ca0bb3aec26de8b2e8c408 490 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 260 267 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 MC49_RS09340 2f21d4da30ca0bb3aec26de8b2e8c408 490 Gene3D G3DSA:3.40.309.10 279 470 2.2E-74 T 29-03-2018 MC49_RS09340 2f21d4da30ca0bb3aec26de8b2e8c408 490 Gene3D G3DSA:3.40.605.10 12 278 5.9E-103 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 MC49_RS09340 2f21d4da30ca0bb3aec26de8b2e8c408 490 SUPERFAMILY SSF53720 11 487 9.69E-173 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 MC49_RS12250 99586479f913c2aa152621f9b48ba22a 275 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 5 266 8.0E-112 T 29-03-2018 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 MC49_RS12250 99586479f913c2aa152621f9b48ba22a 275 SUPERFAMILY SSF161098 13 262 1.59E-55 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS12250 99586479f913c2aa152621f9b48ba22a 275 Gene3D G3DSA:1.10.3720.10 5 271 7.8E-45 T 29-03-2018 MC49_RS12250 99586479f913c2aa152621f9b48ba22a 275 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 6 265 4.1E-104 T 29-03-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 MC49_RS12250 99586479f913c2aa152621f9b48ba22a 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 264 1.8E-28 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS17005 c414ae106a4bb7e00f2a240a4e0acb21 231 SMART SM00382 34 223 1.5E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS17005 c414ae106a4bb7e00f2a240a4e0acb21 231 TIGRFAM TIGR02211 LolD_lipo_ex: lipoprotein releasing system, ATP-binding protein 5 224 3.4E-104 T 29-03-2018 IPR011924 Lipoprotein releasing system, ATP-binding protein GO:0005524|GO:0006810|GO:0016020 MC49_RS17005 c414ae106a4bb7e00f2a240a4e0acb21 231 Pfam PF00005 ABC transporter 25 173 7.1E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS17005 c414ae106a4bb7e00f2a240a4e0acb21 231 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS17005 c414ae106a4bb7e00f2a240a4e0acb21 231 Gene3D G3DSA:3.40.50.300 1 230 2.2E-62 T 29-03-2018 MC49_RS17005 c414ae106a4bb7e00f2a240a4e0acb21 231 SUPERFAMILY SSF52540 5 225 1.61E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS11185 cfee8f81e7498d8de59fe47367cfb0e4 245 Pfam PF04288 MukE-like family 10 235 5.5E-124 T 29-03-2018 IPR007385 Prokaryotic chromosome segregation/condensation protein MukE GO:0005737|GO:0007059|GO:0030261 MC49_RS11185 cfee8f81e7498d8de59fe47367cfb0e4 245 Hamap MF_01802 Chromosome partition protein MukE [mukE]. 10 244 48.039 T 29-03-2018 IPR007385 Prokaryotic chromosome segregation/condensation protein MukE GO:0005737|GO:0007059|GO:0030261 MC49_RS07045 09f47ecad83ce218d4b56140d0b63bc8 448 Pfam PF00860 Permease family 28 408 3.2E-77 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 MC49_RS10995 6189f1163b5b045bc0cea2849cc23874 242 SMART SM00382 27 218 9.5E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS10995 6189f1163b5b045bc0cea2849cc23874 242 SUPERFAMILY SSF52540 3 231 1.21E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS10995 6189f1163b5b045bc0cea2849cc23874 242 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MC49_RS10995 6189f1163b5b045bc0cea2849cc23874 242 Pfam PF00005 ABC transporter 20 170 1.1E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS10995 6189f1163b5b045bc0cea2849cc23874 242 Gene3D G3DSA:3.40.50.300 1 242 1.4E-66 T 29-03-2018 MC49_RS10995 6189f1163b5b045bc0cea2849cc23874 242 PIRSF PIRSF039085 1 242 1.9E-84 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 MC49_RS07665 b9e472d6b510198e0abfefd46c6a32a3 302 TIGRFAM TIGR02797 exbB: tonB-system energizer ExbB 81 288 5.8E-88 T 29-03-2018 IPR014164 TonB-system energizer ExbB type-1 GO:0006810|GO:0016020 MC49_RS07665 b9e472d6b510198e0abfefd46c6a32a3 302 Pfam PF01618 MotA/TolQ/ExbB proton channel family 176 274 6.2E-33 T 29-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 MC49_RS00305 08daabea73ad43af2c9b910276a97169 465 Gene3D G3DSA:1.10.860.10 1 153 3.1E-39 T 29-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal MC49_RS00305 08daabea73ad43af2c9b910276a97169 465 SUPERFAMILY SSF48024 7 120 5.62E-30 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 MC49_RS00305 08daabea73ad43af2c9b910276a97169 465 SUPERFAMILY SSF52540 190 433 1.02E-38 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS00305 08daabea73ad43af2c9b910276a97169 465 Gene3D G3DSA:3.40.50.300 172 451 1.2E-41 T 29-03-2018 MC49_RS00305 08daabea73ad43af2c9b910276a97169 465 Pfam PF00772 DnaB-like helicase N terminal domain 9 112 2.2E-28 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 MC49_RS00305 08daabea73ad43af2c9b910276a97169 465 Pfam PF03796 DnaB-like helicase C terminal domain 190 434 1.2E-65 T 29-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 MC49_RS18900 d05e3b62795d79d44e814ae8f18426d9 713 Gene3D G3DSA:2.40.170.20 176 713 1.4E-74 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MC49_RS18900 d05e3b62795d79d44e814ae8f18426d9 713 Pfam PF00593 TonB dependent receptor 252 712 1.2E-52 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MC49_RS18900 d05e3b62795d79d44e814ae8f18426d9 713 SUPERFAMILY SSF56935 39 713 6.11E-113 T 29-03-2018 MC49_RS18900 d05e3b62795d79d44e814ae8f18426d9 713 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 59 713 6.9E-90 T 29-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 MC49_RS18900 d05e3b62795d79d44e814ae8f18426d9 713 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 696 713 - T 29-03-2018 IPR010917 TonB-dependent receptor, conserved site MC49_RS18900 d05e3b62795d79d44e814ae8f18426d9 713 Gene3D G3DSA:2.170.130.10 28 175 3.2E-24 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MC49_RS18900 d05e3b62795d79d44e814ae8f18426d9 713 Pfam PF07715 TonB-dependent Receptor Plug Domain 59 169 5.4E-20 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MC49_RS13890 27fac173136921a587d5f391adb1f298 196 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 111 121 - T 29-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 MC49_RS13890 27fac173136921a587d5f391adb1f298 196 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 17 30 - T 29-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 MC49_RS13890 27fac173136921a587d5f391adb1f298 196 Gene3D G3DSA:3.40.50.1470 1 195 4.5E-69 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MC49_RS13890 27fac173136921a587d5f391adb1f298 196 SUPERFAMILY SSF53178 4 193 6.02E-70 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MC49_RS13890 27fac173136921a587d5f391adb1f298 196 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 4 190 2.0E-69 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MC49_RS13890 27fac173136921a587d5f391adb1f298 196 Pfam PF01195 Peptidyl-tRNA hydrolase 6 189 1.5E-53 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MC49_RS13890 27fac173136921a587d5f391adb1f298 196 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 4 183 36.212 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MC49_RS11545 6e276f90c8eb38f1d296bc3bf441d311 304 SUPERFAMILY SSF103481 38 141 1.83E-10 T 29-03-2018 MC49_RS11545 6e276f90c8eb38f1d296bc3bf441d311 304 Pfam PF00892 EamA-like transporter family 152 287 5.2E-18 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MC49_RS11545 6e276f90c8eb38f1d296bc3bf441d311 304 Pfam PF00892 EamA-like transporter family 11 137 1.2E-17 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MC49_RS11545 6e276f90c8eb38f1d296bc3bf441d311 304 SUPERFAMILY SSF103481 189 293 4.71E-14 T 29-03-2018 MC49_RS07720 37bbf61187707f1393091e3d31f5ad67 225 Pfam PF06693 Protein of unknown function (DUF1190) 43 210 3.4E-55 T 29-03-2018 IPR009576 Biofilm formation YgiB MC49_RS07720 37bbf61187707f1393091e3d31f5ad67 225 Hamap MF_01188 UPF0441 protein YgiB [ygiB]. 3 225 35.356 T 29-03-2018 IPR009576 Biofilm formation YgiB MC49_RS06095 95b9779f8aaf3091d78df91e901f2092 190 Gene3D G3DSA:1.10.340.30 8 189 2.7E-83 T 29-03-2018 MC49_RS06095 95b9779f8aaf3091d78df91e901f2092 190 TIGRFAM TIGR00624 tag: DNA-3-methyladenine glycosylase I 10 188 1.8E-82 T 29-03-2018 IPR004597 DNA-3-methyladenine glycosylase I GO:0006284|GO:0008725 MC49_RS06095 95b9779f8aaf3091d78df91e901f2092 190 SUPERFAMILY SSF48150 9 188 5.1E-80 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 MC49_RS06095 95b9779f8aaf3091d78df91e901f2092 190 Pfam PF03352 Methyladenine glycosylase 13 187 3.5E-80 T 29-03-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 MC49_RS15425 f3b11aae2c03ae27e64c232ebd7c070a 91 Pfam PF07023 Protein of unknown function (DUF1315) 5 77 2.3E-22 T 29-03-2018 IPR009749 Protein of unknown function DUF1315 MC49_RS05410 707c09927ae7a2ae04ac22e6639f027c 276 Gene3D G3DSA:3.40.140.10 142 276 2.2E-42 T 29-03-2018 MC49_RS05410 707c09927ae7a2ae04ac22e6639f027c 276 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 12 275 32.394 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 MC49_RS05410 707c09927ae7a2ae04ac22e6639f027c 276 PIRSF PIRSF015626 9 276 2.7E-78 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 MC49_RS05410 707c09927ae7a2ae04ac22e6639f027c 276 Pfam PF02634 FdhD/NarQ family 38 274 3.8E-71 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 MC49_RS05410 707c09927ae7a2ae04ac22e6639f027c 276 SUPERFAMILY SSF53927 24 275 2.41E-76 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 MC49_RS05410 707c09927ae7a2ae04ac22e6639f027c 276 Gene3D G3DSA:3.10.20.10 40 127 1.8E-22 T 29-03-2018 MC49_RS05410 707c09927ae7a2ae04ac22e6639f027c 276 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 34 275 8.1E-84 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 MC49_RS14645 41b7b3776bd39ed87c65b6a837aa0f0a 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 8.3E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS14645 41b7b3776bd39ed87c65b6a837aa0f0a 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 8.3E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS14645 41b7b3776bd39ed87c65b6a837aa0f0a 198 SUPERFAMILY SSF46689 4 75 1.75E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 MC49_RS14645 41b7b3776bd39ed87c65b6a837aa0f0a 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 8.7E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MC49_RS14645 41b7b3776bd39ed87c65b6a837aa0f0a 198 Gene3D G3DSA:1.10.357.10 2 193 1.8E-21 T 29-03-2018 MC49_RS07990 e83bc63fe20620024581a4853d98f330 107 PIRSF PIRSF006257 1 107 2.7E-37 T 29-03-2018 IPR007384 Protein of unknown function UCP006257 MC49_RS07990 e83bc63fe20620024581a4853d98f330 107 Pfam PF04287 tRNA pseudouridine synthase C 6 104 4.8E-34 T 29-03-2018 IPR023376 YqcC-like domain MC49_RS07990 e83bc63fe20620024581a4853d98f330 107 Gene3D G3DSA:1.20.1440.40 3 106 8.2E-35 T 29-03-2018 IPR023376 YqcC-like domain MC49_RS07990 e83bc63fe20620024581a4853d98f330 107 SUPERFAMILY SSF158452 1 106 6.93E-36 T 29-03-2018 IPR023376 YqcC-like domain MC49_RS10440 ffd61387aa683aed06dcce5c17cb28e0 228 TIGRFAM TIGR02796 tolQ: protein TolQ 5 219 7.9E-94 T 29-03-2018 IPR014163 Tol-Pal system, TolQ GO:0015031|GO:0016021 MC49_RS10440 ffd61387aa683aed06dcce5c17cb28e0 228 Pfam PF01618 MotA/TolQ/ExbB proton channel family 78 207 9.7E-43 T 29-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 MC49_RS15005 1c05aca413c7a37453e949fa3a637720 380 Pfam PF04536 TPM domain 33 157 6.8E-37 T 29-03-2018 IPR007621 TPM domain MC49_RS15470 6ab98cd0b79805a220d8abd85ef07708 286 Pfam PF12697 Alpha/beta hydrolase family 32 240 5.9E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MC49_RS15470 6ab98cd0b79805a220d8abd85ef07708 286 Gene3D G3DSA:3.40.50.1820 8 286 6.2E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS15470 6ab98cd0b79805a220d8abd85ef07708 286 SUPERFAMILY SSF53474 13 284 6.26E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS15590 26243d15db39cefaa3107727230db201 117 Pfam PF04024 PspC domain 6 63 3.4E-16 T 29-03-2018 IPR007168 Phage shock protein, PspC, N-terminal MC49_RS15590 26243d15db39cefaa3107727230db201 117 TIGRFAM TIGR02978 phageshock_pspC: phage shock protein C 5 117 5.4E-33 T 29-03-2018 IPR014320 Phage shock protein, PspC MC49_RS17610 f689ab6f6364531206a25e2720920ffd 495 Pfam PF11863 Protein of unknown function (DUF3383) 6 494 1.6E-124 T 29-03-2018 IPR021808 Protein of unknown function DUF3383 MC49_RS05020 15573f6fb508774c1340aaa3fff78261 328 Pfam PF03824 High-affinity nickel-transport protein 201 316 3.1E-10 T 29-03-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 MC49_RS05020 15573f6fb508774c1340aaa3fff78261 328 Pfam PF03824 High-affinity nickel-transport protein 64 165 1.2E-21 T 29-03-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 MC49_RS04110 2908592cc5c2477d64381c5e552a0b64 123 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 123 28.497 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MC49_RS04110 2908592cc5c2477d64381c5e552a0b64 123 SUPERFAMILY SSF50193 2 122 7.59E-51 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MC49_RS04110 2908592cc5c2477d64381c5e552a0b64 123 Gene3D G3DSA:2.40.150.20 1 123 8.3E-53 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MC49_RS04110 2908592cc5c2477d64381c5e552a0b64 123 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 123 1.9E-58 T 29-03-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 MC49_RS04110 2908592cc5c2477d64381c5e552a0b64 123 SMART SM01374 1 123 1.1E-84 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MC49_RS04110 2908592cc5c2477d64381c5e552a0b64 123 Pfam PF00238 Ribosomal protein L14p/L23e 1 123 2.1E-54 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MC49_RS04110 2908592cc5c2477d64381c5e552a0b64 123 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 29-03-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MC49_RS10720 6e0ee478aa5babffe8584ea8a8f468f5 450 Pfam PF00324 Amino acid permease 18 388 7.7E-30 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 MC49_RS10720 6e0ee478aa5babffe8584ea8a8f468f5 450 PIRSF PIRSF006060 1 447 2.7E-60 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MC49_RS09675 f557f7090036bf1c09ac691b817eb69a 319 Gene3D G3DSA:3.20.20.70 2 308 7.6E-67 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS09675 f557f7090036bf1c09ac691b817eb69a 319 SUPERFAMILY SSF51395 2 310 3.05E-66 T 29-03-2018 MC49_RS09675 f557f7090036bf1c09ac691b817eb69a 319 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 3 298 2.4E-45 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 MC49_RS08965 d38ce8c44ceac03c00958928317942b7 114 Pfam PF09691 Type II secretion system pilotin lipoprotein (PulS_OutS) 22 108 2.0E-11 T 29-03-2018 IPR019114 Chaperone lipoprotein, PulS/OutS-like MC49_RS08965 d38ce8c44ceac03c00958928317942b7 114 ProDom PD074041 YACC EXPORTED PRECURSOR SIGNAL PERIPLASMIC Y0776 SIMILAR ECS0126 STY0189 ESCHERICHIA 1 114 2.0E-29 T 29-03-2018 MC49_RS03805 7720882eeca300f37657e59e562263df 241 Pfam PF00583 Acetyltransferase (GNAT) family 133 223 2.7E-15 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MC49_RS03805 7720882eeca300f37657e59e562263df 241 Hamap MF_02027 dTDP-fucosamine acetyltransferase [wecD]. 44 235 45.245 T 29-03-2018 IPR012752 dTDP-fucosamine acetyltransferase WecD GO:0008080|GO:0009246 KEGG: 00071+2.3.1.21|MetaCyc: PWY-6111|MetaCyc: PWY-7315 MC49_RS03805 7720882eeca300f37657e59e562263df 241 Gene3D G3DSA:3.40.630.30 80 240 2.9E-23 T 29-03-2018 MC49_RS03805 7720882eeca300f37657e59e562263df 241 TIGRFAM TIGR02382 wecD_rffC: TDP-D-fucosamine acetyltransferase 44 235 3.8E-80 T 29-03-2018 IPR012752 dTDP-fucosamine acetyltransferase WecD GO:0008080|GO:0009246 KEGG: 00071+2.3.1.21|MetaCyc: PWY-6111|MetaCyc: PWY-7315 MC49_RS03805 7720882eeca300f37657e59e562263df 241 SUPERFAMILY SSF55729 45 228 9.83E-27 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS11480 e85038b47c074a3164e02647a5912208 181 Pfam PF00419 Fimbrial protein 33 181 9.1E-22 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS11480 e85038b47c074a3164e02647a5912208 181 Gene3D G3DSA:2.60.40.1090 31 181 2.8E-34 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS11480 e85038b47c074a3164e02647a5912208 181 SUPERFAMILY SSF49401 32 181 7.95E-35 T 29-03-2018 IPR008966 Adhesion domain MC49_RS17170 29b8644361e29d92dd59b6d0ec2929b1 459 Pfam PF13520 Amino acid permease 48 421 2.4E-36 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MC49_RS17170 29b8644361e29d92dd59b6d0ec2929b1 459 PIRSF PIRSF006060 11 454 2.4E-68 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MC49_RS11670 b542464ce3f339f57ccb4acb9bf06778 144 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 135 1.1E-30 T 29-03-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 MC49_RS11670 b542464ce3f339f57ccb4acb9bf06778 144 SUPERFAMILY SSF55961 1 142 9.95E-34 T 29-03-2018 MC49_RS11670 b542464ce3f339f57ccb4acb9bf06778 144 Gene3D G3DSA:3.30.530.20 1 144 3.0E-30 T 29-03-2018 IPR023393 START-like domain MC49_RS02470 41a370f64c0ee705500f767ef7d0384e 381 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 333 350 4.6E-15 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 MC49_RS02470 41a370f64c0ee705500f767ef7d0384e 381 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 56 67 4.6E-15 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 MC49_RS02470 41a370f64c0ee705500f767ef7d0384e 381 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 98 108 4.6E-15 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 MC49_RS02470 41a370f64c0ee705500f767ef7d0384e 381 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 247 259 4.6E-15 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 MC49_RS02470 41a370f64c0ee705500f767ef7d0384e 381 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 155 166 4.6E-15 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 MC49_RS02470 41a370f64c0ee705500f767ef7d0384e 381 SUPERFAMILY SSF56935 22 381 3.43E-77 T 29-03-2018 MC49_RS02470 41a370f64c0ee705500f767ef7d0384e 381 PRINTS PR00183 E.coli/Salmonella-type porin signature 22 38 5.2E-64 T 29-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 MC49_RS02470 41a370f64c0ee705500f767ef7d0384e 381 PRINTS PR00183 E.coli/Salmonella-type porin signature 253 270 5.2E-64 T 29-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 MC49_RS02470 41a370f64c0ee705500f767ef7d0384e 381 PRINTS PR00183 E.coli/Salmonella-type porin signature 98 120 5.2E-64 T 29-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 MC49_RS02470 41a370f64c0ee705500f767ef7d0384e 381 PRINTS PR00183 E.coli/Salmonella-type porin signature 153 175 5.2E-64 T 29-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 MC49_RS02470 41a370f64c0ee705500f767ef7d0384e 381 PRINTS PR00183 E.coli/Salmonella-type porin signature 55 73 5.2E-64 T 29-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 MC49_RS02470 41a370f64c0ee705500f767ef7d0384e 381 PRINTS PR00183 E.coli/Salmonella-type porin signature 287 306 5.2E-64 T 29-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 MC49_RS02470 41a370f64c0ee705500f767ef7d0384e 381 Pfam PF00267 Gram-negative porin 27 381 1.4E-133 T 29-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 MC49_RS02470 41a370f64c0ee705500f767ef7d0384e 381 Gene3D G3DSA:2.40.160.10 10 381 5.6E-54 T 29-03-2018 MC49_RS16025 12a5471606e294d797e5e943bd34899a 179 Pfam PF14002 YniB-like protein 15 179 4.9E-71 T 29-03-2018 IPR025229 YniB-like protein MC49_RS16025 12a5471606e294d797e5e943bd34899a 179 ProDom PD035714 MEMBRANE REGULATOR YNIB TRANSMEMBRANE YFEABCD YFEE PROBABLE LOCUS ESCHERICHIA ECS2432 1 179 2.0E-53 T 29-03-2018 MC49_RS11595 7f730a8bee94aaa05c99a6b3e684268d 80 Pfam PF11823 Protein of unknown function (DUF3343) 3 49 1.7E-6 T 29-03-2018 IPR021778 Domain of unknown function DUF3343 MC49_RS05685 8d17f80e340eccc6bfef9b29c9645f2f 278 SUPERFAMILY SSF51621 7 189 4.4E-30 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 MC49_RS05685 8d17f80e340eccc6bfef9b29c9645f2f 278 Gene3D G3DSA:3.20.20.60 2 191 2.3E-25 T 29-03-2018 MC49_RS05685 8d17f80e340eccc6bfef9b29c9645f2f 278 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 11 157 6.2E-12 T 29-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 MC49_RS10295 0ed87c4f304680311edb42115adc7ac7 176 SUPERFAMILY SSF52218 5 170 3.59E-53 T 29-03-2018 IPR029039 Flavoprotein-like domain MC49_RS10295 0ed87c4f304680311edb42115adc7ac7 176 Pfam PF00258 Flavodoxin 6 160 5.3E-32 T 29-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 MC49_RS10295 0ed87c4f304680311edb42115adc7ac7 176 PIRSF PIRSF038996 1 172 2.2E-69 T 29-03-2018 IPR010086 Flavodoxin, long chain GO:0010181 MC49_RS10295 0ed87c4f304680311edb42115adc7ac7 176 Gene3D G3DSA:3.40.50.360 4 170 2.7E-38 T 29-03-2018 IPR029039 Flavoprotein-like domain MC49_RS10295 0ed87c4f304680311edb42115adc7ac7 176 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 29-03-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 MC49_RS10295 0ed87c4f304680311edb42115adc7ac7 176 TIGRFAM TIGR01752 flav_long: flavodoxin 5 168 5.8E-75 T 29-03-2018 IPR010086 Flavodoxin, long chain GO:0010181 MC49_RS15480 2def08d9ad67979b6ccb29d6594c817d 515 Hamap MF_01599 Na(+)/H(+) antiporter NhaB [nhaB]. 1 515 347.275 T 29-03-2018 IPR004671 Na+/H+ antiporter NhaB GO:0006814|GO:0015385|GO:0016021 MC49_RS15480 2def08d9ad67979b6ccb29d6594c817d 515 TIGRFAM TIGR00774 NhaB: Na+/H+ antiporter NhaB 1 512 9.2E-270 T 29-03-2018 IPR004671 Na+/H+ antiporter NhaB GO:0006814|GO:0015385|GO:0016021 MC49_RS15480 2def08d9ad67979b6ccb29d6594c817d 515 Pfam PF06450 Bacterial Na+/H+ antiporter B (NhaB) 1 512 7.9E-270 T 29-03-2018 IPR004671 Na+/H+ antiporter NhaB GO:0006814|GO:0015385|GO:0016021 MC49_RS03305 d857e195f0aa5caf709cfc0d4fec5ad6 331 Gene3D G3DSA:3.20.20.150 9 301 9.0E-18 T 29-03-2018 MC49_RS03305 d857e195f0aa5caf709cfc0d4fec5ad6 331 SUPERFAMILY SSF51391 11 161 1.99E-5 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MC49_RS03305 d857e195f0aa5caf709cfc0d4fec5ad6 331 ProSitePatterns PS01276 Peptidase family U32 signature. 161 179 - T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 MC49_RS03305 d857e195f0aa5caf709cfc0d4fec5ad6 331 Pfam PF01136 Peptidase family U32 76 330 1.3E-65 T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 MC49_RS13415 4d386d99ad02b2cf829f34907f44a91e 395 Pfam PF04865 Baseplate J-like protein 78 199 2.2E-11 T 29-03-2018 IPR006949 Baseplate protein J-like MC49_RS09000 f780204b7fd82c65fc08db78c094a865 116 Pfam PF02974 Protease inhibitor Inh 27 114 9.6E-8 T 29-03-2018 IPR021140 Alkaline proteinase inhibitor/ Outer membrane lipoprotein Omp19 MC49_RS09000 f780204b7fd82c65fc08db78c094a865 116 Gene3D G3DSA:2.40.128.10 28 115 9.8E-11 T 29-03-2018 MC49_RS09000 f780204b7fd82c65fc08db78c094a865 116 SUPERFAMILY SSF50882 25 113 5.75E-10 T 29-03-2018 IPR016085 Protease inhibitor, beta-barrel domain GO:0004866 MC49_RS07380 47b1f060d49b1beab93bac9665d91ac4 268 SUPERFAMILY SSF161098 61 255 1.44E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS07380 47b1f060d49b1beab93bac9665d91ac4 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 262 4.1E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS07380 47b1f060d49b1beab93bac9665d91ac4 268 Gene3D G3DSA:1.10.3720.10 8 266 3.3E-31 T 29-03-2018 MC49_RS18450 288c04e9ec8a622e3eefb0988d25908a 411 Gene3D G3DSA:3.50.50.60 1 366 2.8E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS18450 288c04e9ec8a622e3eefb0988d25908a 411 SUPERFAMILY SSF51905 269 386 1.2E-57 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS18450 288c04e9ec8a622e3eefb0988d25908a 411 SUPERFAMILY SSF51905 4 178 1.2E-57 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MC49_RS18450 288c04e9ec8a622e3eefb0988d25908a 411 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 5 392 9.2E-128 T 29-03-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 MC49_RS18450 288c04e9ec8a622e3eefb0988d25908a 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 297 313 5.5E-17 T 29-03-2018 MC49_RS18450 288c04e9ec8a622e3eefb0988d25908a 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 282 297 5.5E-17 T 29-03-2018 MC49_RS18450 288c04e9ec8a622e3eefb0988d25908a 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 5.5E-17 T 29-03-2018 MC49_RS18450 288c04e9ec8a622e3eefb0988d25908a 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 157 172 5.5E-17 T 29-03-2018 MC49_RS18450 288c04e9ec8a622e3eefb0988d25908a 411 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 296 309 - T 29-03-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 MC49_RS18450 288c04e9ec8a622e3eefb0988d25908a 411 Pfam PF01494 FAD binding domain 4 315 6.2E-25 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 MC49_RS19090 4a3ca9242eeb2b48f5922580238c4bb3 157 Gene3D G3DSA:3.40.35.10 3 157 1.2E-56 T 29-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 MC49_RS19090 4a3ca9242eeb2b48f5922580238c4bb3 157 SUPERFAMILY SSF52728 3 156 9.81E-52 T 29-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 MC49_RS19090 4a3ca9242eeb2b48f5922580238c4bb3 157 TIGRFAM TIGR00854 pts-sorbose: PTS system, mannose/fructose/sorbose family, IIB component 3 152 3.4E-69 T 29-03-2018 IPR018455 Phosphotransferase system, sorbose subfamily IIB component, subgroup GO:0005737|GO:0008982|GO:0009401 MC49_RS19090 4a3ca9242eeb2b48f5922580238c4bb3 157 Pfam PF03830 PTS system sorbose subfamily IIB component 4 149 7.7E-51 T 29-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 MC49_RS00005 924d6a7415d755fc2bcdf8269132ba4c 134 SUPERFAMILY SSF56059 3 122 1.27E-35 T 29-03-2018 MC49_RS00005 924d6a7415d755fc2bcdf8269132ba4c 134 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 4 122 1.2E-26 T 29-03-2018 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain MC49_RS13535 fdebbef96dfe80c06b4be08a31c403ef 183 SUPERFAMILY SSF52218 5 165 2.33E-46 T 29-03-2018 IPR029039 Flavoprotein-like domain MC49_RS13535 fdebbef96dfe80c06b4be08a31c403ef 183 Pfam PF03358 NADPH-dependent FMN reductase 5 146 2.0E-38 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 MC49_RS13535 fdebbef96dfe80c06b4be08a31c403ef 183 Gene3D G3DSA:3.40.50.360 2 183 1.7E-37 T 29-03-2018 IPR029039 Flavoprotein-like domain MC49_RS01330 8aeb6a5ab380c230404320407a825d44 438 SUPERFAMILY SSF161070 4 437 1.83E-120 T 29-03-2018 MC49_RS01330 8aeb6a5ab380c230404320407a825d44 438 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 39 58 2.4E-11 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MC49_RS01330 8aeb6a5ab380c230404320407a825d44 438 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 10 31 2.4E-11 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MC49_RS01330 8aeb6a5ab380c230404320407a825d44 438 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 417 437 2.4E-11 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MC49_RS01330 8aeb6a5ab380c230404320407a825d44 438 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 84 110 2.4E-11 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MC49_RS01330 8aeb6a5ab380c230404320407a825d44 438 Pfam PF00209 Sodium:neurotransmitter symporter family 140 437 4.7E-34 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MC49_RS01330 8aeb6a5ab380c230404320407a825d44 438 Pfam PF00209 Sodium:neurotransmitter symporter family 3 120 2.1E-19 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MC49_RS07765 042afd5645d11aa26cac2bd63f1c1b6e 254 Gene3D G3DSA:3.30.460.10 4 135 8.8E-13 T 29-03-2018 MC49_RS07765 042afd5645d11aa26cac2bd63f1c1b6e 254 SUPERFAMILY SSF81301 28 77 5.23E-9 T 29-03-2018 MC49_RS07765 042afd5645d11aa26cac2bd63f1c1b6e 254 Pfam PF01909 Nucleotidyltransferase domain 26 68 1.5E-4 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 MC49_RS01270 9ef19b13a9aff64c00fb4e2eeee7ffbd 291 Pfam PF00892 EamA-like transporter family 144 282 9.1E-21 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MC49_RS01270 9ef19b13a9aff64c00fb4e2eeee7ffbd 291 Pfam PF00892 EamA-like transporter family 8 136 3.7E-16 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MC49_RS01270 9ef19b13a9aff64c00fb4e2eeee7ffbd 291 SUPERFAMILY SSF103481 202 287 1.16E-11 T 29-03-2018 MC49_RS01270 9ef19b13a9aff64c00fb4e2eeee7ffbd 291 SUPERFAMILY SSF103481 41 137 6.15E-7 T 29-03-2018 MC49_RS17165 19e8f2536e57afe21b8219aa85aee5ab 261 Pfam PF01925 Sulfite exporter TauE/SafE 20 253 6.8E-33 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MC49_RS15045 db54f1b353715ac64df3aad33624bbb0 234 Pfam PF02508 Rnf-Nqr subunit, membrane protein 5 199 7.8E-65 T 29-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 MC49_RS15045 db54f1b353715ac64df3aad33624bbb0 234 TIGRFAM TIGR01948 rnfE: electron transport complex, RnfABCDGE type, E subunit 6 208 1.7E-84 T 29-03-2018 IPR010968 Electron transport complex, RsxE GO:0016020|GO:0022900 MC49_RS15045 db54f1b353715ac64df3aad33624bbb0 234 Hamap MF_00478 Electron transport complex subunit RsxE [rsxE]. 1 210 28.489 T 29-03-2018 IPR010968 Electron transport complex, RsxE GO:0016020|GO:0022900 MC49_RS15045 db54f1b353715ac64df3aad33624bbb0 234 PIRSF PIRSF006102 1 219 4.6E-79 T 29-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 MC49_RS03780 457eb8c71c310fbdeb689585f1b335f2 253 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 72 238 5.7E-53 T 29-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 MC49_RS03780 457eb8c71c310fbdeb689585f1b335f2 253 Hamap MF_01001 UDP-N-acetyl-D-mannosaminuronic acid transferase [wecG]. 8 253 58.156 T 29-03-2018 IPR023085 UDP-N-acetyl-D-mannosaminuronic acid transferase GO:0009246|GO:0016758 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 MC49_RS03780 457eb8c71c310fbdeb689585f1b335f2 253 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 68 244 1.1E-71 T 29-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 MC49_RS16750 14010dd316434ed8d1699969453db9f8 252 PRINTS PR01805 VacJ lipoprotein signature 139 156 5.6E-33 T 29-03-2018 IPR007428 MlaA lipoprotein GO:0016020 MC49_RS16750 14010dd316434ed8d1699969453db9f8 252 PRINTS PR01805 VacJ lipoprotein signature 49 65 5.6E-33 T 29-03-2018 IPR007428 MlaA lipoprotein GO:0016020 MC49_RS16750 14010dd316434ed8d1699969453db9f8 252 PRINTS PR01805 VacJ lipoprotein signature 31 44 5.6E-33 T 29-03-2018 IPR007428 MlaA lipoprotein GO:0016020 MC49_RS16750 14010dd316434ed8d1699969453db9f8 252 PRINTS PR01805 VacJ lipoprotein signature 100 117 5.6E-33 T 29-03-2018 IPR007428 MlaA lipoprotein GO:0016020 MC49_RS16750 14010dd316434ed8d1699969453db9f8 252 Pfam PF04333 MlaA lipoprotein 30 223 1.1E-63 T 29-03-2018 IPR007428 MlaA lipoprotein GO:0016020 MC49_RS05390 be70c1559ed2dfe9cb3acb93f2340359 450 Pfam PF04575 Protein of unknown function (DUF560) 209 450 3.0E-34 T 29-03-2018 IPR007655 Protein of unknown function DUF560 MC49_RS05390 be70c1559ed2dfe9cb3acb93f2340359 450 Gene3D G3DSA:1.25.40.10 25 400 3.7E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MC49_RS05390 be70c1559ed2dfe9cb3acb93f2340359 450 SUPERFAMILY SSF48452 46 145 2.58E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MC49_RS17000 57663177c306defca805625b17881898 415 Pfam PF02687 FtsX-like permease family 303 408 7.6E-12 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MC49_RS17000 57663177c306defca805625b17881898 415 TIGRFAM TIGR02213 lolE_release: lipoprotein releasing system, transmembrane protein LolE 6 415 1.6E-189 T 29-03-2018 IPR011926 Lipoprotein-releasing system transmembrane protein LolC/E, gammaproteobacteria type GO:0006810|GO:0009276|GO:0016021 MC49_RS17000 57663177c306defca805625b17881898 415 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 5 414 1.1E-145 T 29-03-2018 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 MC49_RS17000 57663177c306defca805625b17881898 415 Pfam PF12704 MacB-like periplasmic core domain 28 238 3.3E-14 T 29-03-2018 IPR025857 MacB-like periplasmic core domain MC49_RS03195 90d719645607ff630dd07c1cb28e1e39 408 SUPERFAMILY SSF103365 9 408 7.32E-141 T 29-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 MC49_RS03195 90d719645607ff630dd07c1cb28e1e39 408 ProSitePatterns PS01288 Uncharacterized protein family UPF0027 signature. 33 62 - T 29-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 MC49_RS03195 90d719645607ff630dd07c1cb28e1e39 408 Pfam PF01139 tRNA-splicing ligase RtcB 33 408 1.1E-137 T 29-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 MC49_RS02820 112aabeb2028ceeb92245b4ea69ce844 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 282 7.6E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS02820 112aabeb2028ceeb92245b4ea69ce844 286 SUPERFAMILY SSF161098 6 275 3.64E-54 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS02820 112aabeb2028ceeb92245b4ea69ce844 286 Gene3D G3DSA:1.10.3720.10 9 285 1.7E-43 T 29-03-2018 MC49_RS09775 9958a225801da917017e46b88ff3702e 133 Pfam PF07417 Transcriptional regulator Crl 7 121 8.3E-49 T 29-03-2018 IPR009986 Sigma factor-binding protein Crl GO:0005737|GO:0045893 MC49_RS09775 9958a225801da917017e46b88ff3702e 133 Hamap MF_01178 Sigma factor-binding protein Crl [crl]. 2 128 29.145 T 29-03-2018 IPR009986 Sigma factor-binding protein Crl GO:0005737|GO:0045893 MC49_RS04290 50380bcceca45e26466a119a9fdc0fa5 444 PIRSF PIRSF005353 6 444 1.3E-171 T 29-03-2018 IPR026033 Purine permease PbuG-like MC49_RS04290 50380bcceca45e26466a119a9fdc0fa5 444 Pfam PF00860 Permease family 30 404 2.4E-43 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 MC49_RS10150 9f36fb8484edf9851e4200f90abfa3a8 184 Gene3D G3DSA:3.30.160.150 20 173 4.0E-44 T 29-03-2018 MC49_RS10150 9f36fb8484edf9851e4200f90abfa3a8 184 Hamap MF_01186 LPS-assembly lipoprotein LptE [lptE]. 5 164 24.252 T 29-03-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 MC49_RS10150 9f36fb8484edf9851e4200f90abfa3a8 184 Pfam PF04390 Lipopolysaccharide-assembly 36 159 1.9E-11 T 29-03-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 MC49_RS11955 171314dc22108114ac102a2454c62aa8 494 TIGRFAM TIGR03355 VI_chp_2: type VI secretion protein, EvpB/VC_A0108 family 20 492 2.4E-209 T 29-03-2018 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath MC49_RS11955 171314dc22108114ac102a2454c62aa8 494 Pfam PF05943 Type VI secretion protein, EvpB/VC_A0108, tail sheath 68 491 1.9E-174 T 29-03-2018 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath MC49_RS04925 bf165a3d522203f57115cee570e25e45 322 Gene3D G3DSA:1.25.40.20 25 266 6.6E-8 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain MC49_RS04925 bf165a3d522203f57115cee570e25e45 322 SUPERFAMILY SSF48403 36 94 6.06E-7 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain MC49_RS08515 bba061685b23c4d6f699cd94547eed23 111 Gene3D G3DSA:2.102.10.10 1 111 2.6E-21 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MC49_RS08515 bba061685b23c4d6f699cd94547eed23 111 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 3 107 4.9E-34 T 29-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 MC49_RS08515 bba061685b23c4d6f699cd94547eed23 111 Pfam PF13806 Rieske-like [2Fe-2S] domain 3 106 1.2E-37 T 29-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 MC49_RS08515 bba061685b23c4d6f699cd94547eed23 111 SUPERFAMILY SSF50022 1 107 1.61E-35 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MC49_RS04535 c400ec7d29069406d9f0333e39dcf339 211 Gene3D G3DSA:3.20.20.70 1 211 3.4E-35 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS04535 c400ec7d29069406d9f0333e39dcf339 211 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 39 48 - T 29-03-2018 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 MC49_RS04535 c400ec7d29069406d9f0333e39dcf339 211 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 9 208 1.1E-84 T 29-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 MC49_RS04535 c400ec7d29069406d9f0333e39dcf339 211 Pfam PF01081 KDPG and KHG aldolase 9 202 4.3E-83 T 29-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 MC49_RS04535 c400ec7d29069406d9f0333e39dcf339 211 SUPERFAMILY SSF51569 6 210 5.31E-69 T 29-03-2018 MC49_RS04535 c400ec7d29069406d9f0333e39dcf339 211 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 127 140 - T 29-03-2018 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 MC49_RS12515 c2a3490f4c220da6bef4dbe2b2e368f6 138 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 15 35 - T 29-03-2018 IPR019776 Flagellar basal body rod protein, conserved site MC49_RS12515 c2a3490f4c220da6bef4dbe2b2e368f6 138 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 6 136 3.8E-39 T 29-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 MC49_RS12515 c2a3490f4c220da6bef4dbe2b2e368f6 138 Pfam PF00460 Flagella basal body rod protein 11 39 4.6E-9 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 MC49_RS12515 c2a3490f4c220da6bef4dbe2b2e368f6 138 PIRSF PIRSF002889 1 138 1.3E-42 T 29-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 MC49_RS10645 9e922b4aef9551ba049b2ccb8c5919b2 378 Gene3D G3DSA:3.40.1710.10 46 197 2.1E-23 T 29-03-2018 MC49_RS10645 9e922b4aef9551ba049b2ccb8c5919b2 378 Pfam PF12698 ABC-2 family transporter protein 31 370 6.7E-42 T 29-03-2018 MC49_RS14910 5f56d82dce761db4465adf308cd69806 211 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 17 208 5.7E-56 T 29-03-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like MC49_RS14910 5f56d82dce761db4465adf308cd69806 211 SUPERFAMILY SSF51197 14 209 1.14E-59 T 29-03-2018 MC49_RS14910 5f56d82dce761db4465adf308cd69806 211 Gene3D G3DSA:2.60.120.590 10 211 2.5E-47 T 29-03-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like MC49_RS18910 8856e7ae911b29264c1bce906c626219 459 Pfam PF01235 Sodium:alanine symporter family 53 447 5.6E-145 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MC49_RS18910 8856e7ae911b29264c1bce906c626219 459 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 91 106 - T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MC49_RS18910 8856e7ae911b29264c1bce906c626219 459 PRINTS PR00175 Sodium/alanine symporter signature 91 113 2.6E-52 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MC49_RS18910 8856e7ae911b29264c1bce906c626219 459 PRINTS PR00175 Sodium/alanine symporter signature 350 372 2.6E-52 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MC49_RS18910 8856e7ae911b29264c1bce906c626219 459 PRINTS PR00175 Sodium/alanine symporter signature 212 231 2.6E-52 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MC49_RS18910 8856e7ae911b29264c1bce906c626219 459 PRINTS PR00175 Sodium/alanine symporter signature 184 202 2.6E-52 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MC49_RS18910 8856e7ae911b29264c1bce906c626219 459 PRINTS PR00175 Sodium/alanine symporter signature 307 325 2.6E-52 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MC49_RS18910 8856e7ae911b29264c1bce906c626219 459 PRINTS PR00175 Sodium/alanine symporter signature 409 429 2.6E-52 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MC49_RS18910 8856e7ae911b29264c1bce906c626219 459 TIGRFAM TIGR00835 agcS: amino acid carrier protein 16 439 1.6E-151 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MC49_RS13075 69cc42a89716829922ca0d6071ab7001 353 Pfam PF04233 Phage Mu protein F like protein 144 259 1.4E-6 T 29-03-2018 IPR006528 Phage head morphogenesis domain MC49_RS16180 c2baba8a43370d5be57d330b35a32d7e 168 Pfam PF07262 CDI immunity protein 10 163 6.4E-54 T 29-03-2018 IPR009888 Immunity protein CdiI MC49_RS16180 c2baba8a43370d5be57d330b35a32d7e 168 Gene3D G3DSA:3.40.1590.10 8 163 6.3E-38 T 29-03-2018 MC49_RS16180 c2baba8a43370d5be57d330b35a32d7e 168 SUPERFAMILY SSF160207 5 164 9.81E-37 T 29-03-2018 MC49_RS15610 353f6cd35ddb005f8d1256d839aafdb3 562 Gene3D G3DSA:3.90.76.10 57 220 2.6E-31 T 29-03-2018 MC49_RS15610 353f6cd35ddb005f8d1256d839aafdb3 562 SUPERFAMILY SSF53850 48 549 1.23E-134 T 29-03-2018 MC49_RS15610 353f6cd35ddb005f8d1256d839aafdb3 562 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 91 470 9.2E-85 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain MC49_RS15610 353f6cd35ddb005f8d1256d839aafdb3 562 Gene3D G3DSA:3.40.190.10 221 316 6.4E-22 T 29-03-2018 MC49_RS15610 353f6cd35ddb005f8d1256d839aafdb3 562 Gene3D G3DSA:3.10.105.10 317 523 1.9E-55 T 29-03-2018 MC49_RS15610 353f6cd35ddb005f8d1256d839aafdb3 562 PIRSF PIRSF002741 5 551 8.1E-92 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MC49_RS14775 598ab4b74085fb97d639e5131365804f 349 SUPERFAMILY SSF56601 15 326 2.49E-80 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MC49_RS14775 598ab4b74085fb97d639e5131365804f 349 Pfam PF00144 Beta-lactamase 15 320 3.7E-58 T 29-03-2018 IPR001466 Beta-lactamase-related MC49_RS14775 598ab4b74085fb97d639e5131365804f 349 Gene3D G3DSA:3.40.710.10 5 338 1.8E-71 T 29-03-2018 MC49_RS08955 b7de886990102cc7c00ed21033f648c4 515 Pfam PF05231 MASE1 11 281 7.1E-41 T 29-03-2018 IPR007895 MASE1 MC49_RS08955 b7de886990102cc7c00ed21033f648c4 515 SUPERFAMILY SSF55874 395 506 2.88E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS08955 b7de886990102cc7c00ed21033f648c4 515 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 424 506 2.9E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS08955 b7de886990102cc7c00ed21033f648c4 515 Pfam PF07730 Histidine kinase 317 380 6.3E-14 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MC49_RS08955 b7de886990102cc7c00ed21033f648c4 515 SMART SM00387 419 509 7.3E-9 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS08955 b7de886990102cc7c00ed21033f648c4 515 Gene3D G3DSA:3.30.565.10 378 515 3.6E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain MC49_RS14665 b19c9eea76117d928cb38b79d4f9d948 167 Pfam PF14096 Domain of unknown function (DUF4274) 21 95 5.6E-25 T 29-03-2018 IPR025369 Domain of unknown function DUF4274 MC49_RS16795 e7da41bea51c5c8757808347ebaa1237 158 Pfam PF00959 Phage lysozyme 43 148 2.2E-23 T 29-03-2018 IPR002196 Glycoside hydrolase, family 24 GO:0003796|GO:0009253|GO:0016998 MC49_RS16795 e7da41bea51c5c8757808347ebaa1237 158 Gene3D G3DSA:1.10.530.40 1 158 2.5E-49 T 29-03-2018 IPR023347 Lysozyme domain GO:0003796 MC49_RS16795 e7da41bea51c5c8757808347ebaa1237 158 SUPERFAMILY SSF53955 9 156 2.0E-50 T 29-03-2018 IPR023346 Lysozyme-like domain MC49_RS11965 fbf2e541e5779cbad1e10dc0ea8a0e6b 192 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 33 73 1.5E-8 T 29-03-2018 IPR006530 YD repeat MC49_RS11965 fbf2e541e5779cbad1e10dc0ea8a0e6b 192 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 78 112 1.8E-6 T 29-03-2018 IPR006530 YD repeat MC49_RS11965 fbf2e541e5779cbad1e10dc0ea8a0e6b 192 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 2 31 1.3E-4 T 29-03-2018 IPR006530 YD repeat MC49_RS11965 fbf2e541e5779cbad1e10dc0ea8a0e6b 192 Pfam PF05593 RHS Repeat 33 67 6.3E-8 T 29-03-2018 IPR031325 RHS repeat MC49_RS11965 fbf2e541e5779cbad1e10dc0ea8a0e6b 192 Pfam PF05593 RHS Repeat 12 44 6.3E-8 T 29-03-2018 IPR031325 RHS repeat MC49_RS11965 fbf2e541e5779cbad1e10dc0ea8a0e6b 192 SUPERFAMILY SSF69304 5 138 3.4E-5 T 29-03-2018 MC49_RS06890 67841e29460854fd0729251f522d9bdb 102 TIGRFAM TIGR01715 phage_lam_T: phage tail assembly protein T 2 100 8.0E-31 T 29-03-2018 IPR009350 Minor tail T MC49_RS06890 67841e29460854fd0729251f522d9bdb 102 Pfam PF06223 Minor tail protein T 2 100 2.7E-31 T 29-03-2018 IPR009350 Minor tail T MC49_RS00945 4cc3c0c6e27cb8894ac7eddbb62651dd 302 Pfam PF04381 Putative exonuclease, RdgC 1 299 5.2E-126 T 29-03-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 MC49_RS00945 4cc3c0c6e27cb8894ac7eddbb62651dd 302 Hamap MF_00194 Recombination-associated protein RdgC [rdgC]. 1 301 40.648 T 29-03-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 MC49_RS17905 06283862b98f0d115dd4c3e36bf984bb 106 Gene3D G3DSA:2.60.40.420 10 104 7.4E-9 T 29-03-2018 IPR008972 Cupredoxin MC49_RS17905 06283862b98f0d115dd4c3e36bf984bb 106 SUPERFAMILY SSF49503 7 104 6.42E-15 T 29-03-2018 IPR008972 Cupredoxin MC49_RS17905 06283862b98f0d115dd4c3e36bf984bb 106 Pfam PF13473 Cupredoxin-like domain 3 105 8.1E-28 T 29-03-2018 IPR028096 EfeO-type cupredoxin-like domain MC49_RS17515 8e4d1619beea6df2665751e047c7ab86 38 Pfam PF06528 Phage P2 GpE 1 36 1.1E-18 T 29-03-2018 IPR009493 Burkholderia phage phiE202, Gp27 MC49_RS10195 4cce4e6f317eb6c5997ba1749509225b 165 SUPERFAMILY SSF52833 11 154 6.52E-26 T 29-03-2018 IPR012336 Thioredoxin-like fold MC49_RS10195 4cce4e6f317eb6c5997ba1749509225b 165 Pfam PF00578 AhpC/TSA family 40 145 3.1E-13 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MC49_RS10195 4cce4e6f317eb6c5997ba1749509225b 165 Gene3D G3DSA:3.40.30.10 26 160 2.4E-21 T 29-03-2018 MC49_RS07445 f41fd9d352bb2c625e509b7109e9baca 222 Pfam PF10144 Bacterial virulence factor haemolysin 1 162 1.4E-63 T 29-03-2018 IPR019305 Uncharacterised protein family Smp MC49_RS12295 f15da275381be104f6ffe7d494610f14 194 Gene3D G3DSA:3.40.50.360 1 193 6.2E-31 T 29-03-2018 IPR029039 Flavoprotein-like domain MC49_RS12295 f15da275381be104f6ffe7d494610f14 194 SUPERFAMILY SSF52218 1 188 3.43E-33 T 29-03-2018 IPR029039 Flavoprotein-like domain MC49_RS12295 f15da275381be104f6ffe7d494610f14 194 Pfam PF02525 Flavodoxin-like fold 2 186 6.6E-32 T 29-03-2018 IPR003680 Flavodoxin-like fold MC49_RS18230 ebd9c11c61503e62988b4f51477b75b7 145 PRINTS PR01438 Universal stress protein signature 123 145 5.9E-11 T 29-03-2018 IPR006015 Universal stress protein A MC49_RS18230 ebd9c11c61503e62988b4f51477b75b7 145 PRINTS PR01438 Universal stress protein signature 2 20 5.9E-11 T 29-03-2018 IPR006015 Universal stress protein A MC49_RS18230 ebd9c11c61503e62988b4f51477b75b7 145 PRINTS PR01438 Universal stress protein signature 106 118 5.9E-11 T 29-03-2018 IPR006015 Universal stress protein A MC49_RS18230 ebd9c11c61503e62988b4f51477b75b7 145 Gene3D G3DSA:3.40.50.620 1 144 1.0E-23 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS18230 ebd9c11c61503e62988b4f51477b75b7 145 SUPERFAMILY SSF52402 2 145 1.76E-25 T 29-03-2018 MC49_RS18230 ebd9c11c61503e62988b4f51477b75b7 145 Pfam PF00582 Universal stress protein family 1 145 4.9E-21 T 29-03-2018 IPR006016 UspA GO:0006950 MC49_RS00120 972a568c6459455f55ed50dd5ec479e9 156 Pfam PF08875 Domain of unknown function (DUF1833) 6 143 6.6E-8 T 29-03-2018 IPR014974 Domain of unknown function DUF1833 MC49_RS00070 2eb6ae1e27f7736e0a1f1fc56e45ea7e 429 PRINTS PR00758 Arsenical pump membrane protein signature 217 242 2.1E-121 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MC49_RS00070 2eb6ae1e27f7736e0a1f1fc56e45ea7e 429 PRINTS PR00758 Arsenical pump membrane protein signature 323 345 2.1E-121 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MC49_RS00070 2eb6ae1e27f7736e0a1f1fc56e45ea7e 429 PRINTS PR00758 Arsenical pump membrane protein signature 364 389 2.1E-121 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MC49_RS00070 2eb6ae1e27f7736e0a1f1fc56e45ea7e 429 PRINTS PR00758 Arsenical pump membrane protein signature 144 168 2.1E-121 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MC49_RS00070 2eb6ae1e27f7736e0a1f1fc56e45ea7e 429 PRINTS PR00758 Arsenical pump membrane protein signature 278 302 2.1E-121 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MC49_RS00070 2eb6ae1e27f7736e0a1f1fc56e45ea7e 429 PRINTS PR00758 Arsenical pump membrane protein signature 101 125 2.1E-121 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MC49_RS00070 2eb6ae1e27f7736e0a1f1fc56e45ea7e 429 PRINTS PR00758 Arsenical pump membrane protein signature 397 421 2.1E-121 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MC49_RS00070 2eb6ae1e27f7736e0a1f1fc56e45ea7e 429 PRINTS PR00758 Arsenical pump membrane protein signature 177 200 2.1E-121 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MC49_RS00070 2eb6ae1e27f7736e0a1f1fc56e45ea7e 429 Pfam PF02040 Arsenical pump membrane protein 4 423 1.2E-164 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MC49_RS00070 2eb6ae1e27f7736e0a1f1fc56e45ea7e 429 TIGRFAM TIGR00935 2a45: arsenite/antimonite efflux pump membrane protein 3 427 1.7E-217 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 MC49_RS06510 8eedffc5b2ae68dcb2f12043675df649 274 SUPERFAMILY SSF53649 1 255 6.05E-49 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 MC49_RS06510 8eedffc5b2ae68dcb2f12043675df649 274 Gene3D G3DSA:3.40.720.10 2 258 6.2E-36 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 MC49_RS06510 8eedffc5b2ae68dcb2f12043675df649 274 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 5 209 2.1E-14 T 29-03-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 MC49_RS11395 e514764544bd4830678b0c87868cc50b 231 Pfam PF04474 Protein of unknown function (DUF554) 3 225 8.4E-67 T 29-03-2018 IPR007563 Protein of unknown function DUF554 MC49_RS17830 2d97a6f2824994a1917bede668dd759e 72 Pfam PF13986 Domain of unknown function (DUF4224) 8 51 1.1E-16 T 29-03-2018 IPR025319 Domain of unknown function DUF4224 MC49_RS12630 b4fe6c3b276f583042e7875010e17265 243 Pfam PF02108 Flagellar assembly protein FliH 109 233 9.9E-35 T 29-03-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE MC49_RS12630 b4fe6c3b276f583042e7875010e17265 243 PRINTS PR01003 Flagellar assembly protein FliH signature 109 128 3.2E-57 T 29-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 MC49_RS12630 b4fe6c3b276f583042e7875010e17265 243 PRINTS PR01003 Flagellar assembly protein FliH signature 67 89 3.2E-57 T 29-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 MC49_RS12630 b4fe6c3b276f583042e7875010e17265 243 PRINTS PR01003 Flagellar assembly protein FliH signature 147 169 3.2E-57 T 29-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 MC49_RS12630 b4fe6c3b276f583042e7875010e17265 243 PRINTS PR01003 Flagellar assembly protein FliH signature 129 146 3.2E-57 T 29-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 MC49_RS12630 b4fe6c3b276f583042e7875010e17265 243 PRINTS PR01003 Flagellar assembly protein FliH signature 198 214 3.2E-57 T 29-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 MC49_RS12630 b4fe6c3b276f583042e7875010e17265 243 PRINTS PR01003 Flagellar assembly protein FliH signature 9 28 3.2E-57 T 29-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 MC49_RS12630 b4fe6c3b276f583042e7875010e17265 243 PRINTS PR01003 Flagellar assembly protein FliH signature 170 197 3.2E-57 T 29-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 MC49_RS12630 b4fe6c3b276f583042e7875010e17265 243 PRINTS PR01003 Flagellar assembly protein FliH signature 90 108 3.2E-57 T 29-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 MC49_RS12630 b4fe6c3b276f583042e7875010e17265 243 PRINTS PR01003 Flagellar assembly protein FliH signature 215 240 3.2E-57 T 29-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 MC49_RS02285 f6edadc8e6282836225f0cbcaef53983 115 Pfam PF11190 Protein of unknown function (DUF2976) 27 113 6.8E-29 T 29-03-2018 IPR021356 Integrating conjugative element protein PFL4702 MC49_RS02285 f6edadc8e6282836225f0cbcaef53983 115 TIGRFAM TIGR03745 conj_TIGR03745: integrating conjugative element membrane protein, PFL_4702 family 16 114 1.5E-31 T 29-03-2018 IPR021356 Integrating conjugative element protein PFL4702 MC49_RS07225 5bd35622adc766c8c5535a7a6ae6f9d4 298 Gene3D G3DSA:3.40.190.10 182 263 1.1E-9 T 29-03-2018 MC49_RS07225 5bd35622adc766c8c5535a7a6ae6f9d4 298 SUPERFAMILY SSF46785 4 88 9.52E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS07225 5bd35622adc766c8c5535a7a6ae6f9d4 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 5.4E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MC49_RS07225 5bd35622adc766c8c5535a7a6ae6f9d4 298 Gene3D G3DSA:3.40.190.10 94 181 4.7E-11 T 29-03-2018 MC49_RS07225 5bd35622adc766c8c5535a7a6ae6f9d4 298 SUPERFAMILY SSF53850 88 292 3.08E-25 T 29-03-2018 MC49_RS07225 5bd35622adc766c8c5535a7a6ae6f9d4 298 Gene3D G3DSA:1.10.10.10 3 82 4.5E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS07225 5bd35622adc766c8c5535a7a6ae6f9d4 298 Pfam PF03466 LysR substrate binding domain 90 292 4.9E-23 T 29-03-2018 IPR005119 LysR, substrate-binding MC49_RS02645 087dca2986a07c71375fa2b0f7d38ee4 642 SUPERFAMILY SSF56935 34 642 4.03E-83 T 29-03-2018 MC49_RS02645 087dca2986a07c71375fa2b0f7d38ee4 642 Pfam PF07715 TonB-dependent Receptor Plug Domain 35 135 2.0E-17 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MC49_RS02645 087dca2986a07c71375fa2b0f7d38ee4 642 Gene3D G3DSA:2.170.130.10 32 146 7.1E-21 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MC49_RS02645 087dca2986a07c71375fa2b0f7d38ee4 642 Gene3D G3DSA:2.40.170.20 147 642 5.6E-52 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MC49_RS02645 087dca2986a07c71375fa2b0f7d38ee4 642 Pfam PF00593 TonB dependent receptor 181 641 5.2E-31 T 29-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 MC49_RS10105 9ab1a2b55363a589b3bea8e4605ac69d 370 Pfam PF01098 Cell cycle protein 20 364 2.4E-120 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 MC49_RS10105 9ab1a2b55363a589b3bea8e4605ac69d 370 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 17 364 4.9E-137 T 29-03-2018 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 MC49_RS10105 9ab1a2b55363a589b3bea8e4605ac69d 370 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 321 345 - T 29-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 MC49_RS08770 78a9137756cc1d07ef62136e095bcbf6 463 Gene3D G3DSA:2.30.40.10 1 62 1.2E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS08770 78a9137756cc1d07ef62136e095bcbf6 463 Gene3D G3DSA:3.20.20.140 63 278 4.1E-51 T 29-03-2018 MC49_RS08770 78a9137756cc1d07ef62136e095bcbf6 463 Gene3D G3DSA:3.20.20.140 279 422 2.3E-40 T 29-03-2018 MC49_RS08770 78a9137756cc1d07ef62136e095bcbf6 463 SUPERFAMILY SSF51338 1 53 2.1E-36 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS08770 78a9137756cc1d07ef62136e095bcbf6 463 SUPERFAMILY SSF51338 381 453 2.1E-36 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 MC49_RS08770 78a9137756cc1d07ef62136e095bcbf6 463 SUPERFAMILY SSF51556 54 381 3.21E-94 T 29-03-2018 IPR032466 Metal-dependent hydrolase MC49_RS08770 78a9137756cc1d07ef62136e095bcbf6 463 Pfam PF01979 Amidohydrolase family 50 435 1.7E-22 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 MC49_RS08770 78a9137756cc1d07ef62136e095bcbf6 463 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 4 453 1.4E-183 T 29-03-2018 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: R-HSA-399956 MC49_RS09850 b1a479df548dbcec50146080964f3154 519 TIGRFAM TIGR01434 glu_cys_ligase: glutamate--cysteine ligase 6 514 2.4E-237 T 29-03-2018 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MC49_RS09850 b1a479df548dbcec50146080964f3154 519 Pfam PF04262 Glutamate-cysteine ligase 10 380 3.2E-172 T 29-03-2018 IPR007370 Glutamate--cysteine ligase GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MC49_RS09850 b1a479df548dbcec50146080964f3154 519 Hamap MF_00578 Glutamate--cysteine ligase [gshA]. 1 519 220.33 T 29-03-2018 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MC49_RS09850 b1a479df548dbcec50146080964f3154 519 SUPERFAMILY SSF55931 4 514 3.4E-202 T 29-03-2018 MC49_RS05310 238109ce9e9f04022bbeba6d47254f33 426 Pfam PF13520 Amino acid permease 10 393 9.9E-28 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MC49_RS05310 238109ce9e9f04022bbeba6d47254f33 426 PIRSF PIRSF006060 1 425 4.8E-41 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MC49_RS02740 7b920bfdd17ce4f4e7c32f462a1847b6 430 Gene3D G3DSA:3.40.50.300 81 356 1.3E-73 T 29-03-2018 MC49_RS02740 7b920bfdd17ce4f4e7c32f462a1847b6 430 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 14 429 1.5E-125 T 29-03-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MC49_RS02740 7b920bfdd17ce4f4e7c32f462a1847b6 430 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 140 349 2.5E-66 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MC49_RS02740 7b920bfdd17ce4f4e7c32f462a1847b6 430 SMART SM00382 152 333 6.6E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS02740 7b920bfdd17ce4f4e7c32f462a1847b6 430 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 340 349 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 MC49_RS02740 7b920bfdd17ce4f4e7c32f462a1847b6 430 SUPERFAMILY SSF52540 85 355 5.88E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS17395 98cf5ba4f3dce97f6c05bf6b98cf0e90 206 Gene3D G3DSA:3.10.450.50 25 167 2.0E-12 T 29-03-2018 MC49_RS17395 98cf5ba4f3dce97f6c05bf6b98cf0e90 206 SUPERFAMILY SSF54427 24 152 2.05E-15 T 29-03-2018 IPR032710 NTF2-like domain MC49_RS17395 98cf5ba4f3dce97f6c05bf6b98cf0e90 206 Pfam PF13474 SnoaL-like domain 33 152 1.1E-6 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain MC49_RS04655 b5f4313d2e4770a0e2e91ff0ccc2855d 286 Pfam PF04976 DMSO reductase anchor subunit (DmsC) 1 276 6.9E-87 T 29-03-2018 IPR007059 DMSO reductase anchor subunit (DmsC) GO:0016021|GO:0019645 MC49_RS04655 b5f4313d2e4770a0e2e91ff0ccc2855d 286 Gene3D G3DSA:1.20.1630.10 3 284 4.7E-42 T 29-03-2018 MC49_RS02560 862835babb8e42ccedbbb94fb792b622 453 TIGRFAM TIGR04298 his_histam_anti: histidine-histamine antiporter 11 434 6.5E-239 T 29-03-2018 IPR027562 Histidine-histamine antiporter MC49_RS02560 862835babb8e42ccedbbb94fb792b622 453 PIRSF PIRSF006060 3 451 5.9E-60 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MC49_RS02560 862835babb8e42ccedbbb94fb792b622 453 Pfam PF13520 Amino acid permease 13 419 1.2E-55 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MC49_RS07770 77810a0c287a63fac6938623b9d2a279 204 Pfam PF01810 LysE type translocator 15 203 9.1E-35 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MC49_RS07770 77810a0c287a63fac6938623b9d2a279 204 PIRSF PIRSF006324 1 204 5.7E-57 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MC49_RS13790 8c147353e8506e21c1b02a5d18d2e5b1 274 SUPERFAMILY SSF63380 5 137 7.94E-13 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 MC49_RS13790 8c147353e8506e21c1b02a5d18d2e5b1 274 Pfam PF04954 Siderophore-interacting protein 139 255 1.1E-30 T 29-03-2018 IPR007037 Siderophore-interacting protein MC49_RS13790 8c147353e8506e21c1b02a5d18d2e5b1 274 Gene3D G3DSA:2.40.30.10 6 132 1.6E-26 T 29-03-2018 MC49_RS13790 8c147353e8506e21c1b02a5d18d2e5b1 274 Pfam PF08021 Siderophore-interacting FAD-binding domain 17 132 1.7E-35 T 29-03-2018 IPR013113 FAD-binding 9, siderophore-interacting MC49_RS13790 8c147353e8506e21c1b02a5d18d2e5b1 274 Gene3D G3DSA:3.40.50.80 135 274 1.5E-33 T 29-03-2018 MC49_RS12875 cffcb5a7c74ea5cb3ca620afe05f0190 204 Pfam PF04404 ERF superfamily 4 140 1.3E-23 T 29-03-2018 IPR007499 Essential recombination function protein MC49_RS09705 07b9bc04c8505ba9822f9f47aa2cdea9 447 TIGRFAM TIGR01936 nqrA: NADH:ubiquinone oxidoreductase, Na(+)-translocating, A subunit 2 447 2.0E-177 T 29-03-2018 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 MC49_RS09705 07b9bc04c8505ba9822f9f47aa2cdea9 447 Pfam PF11973 NQRA C-terminal domain 262 307 1.5E-19 T 29-03-2018 IPR022615 Na(+)-translocating NADH-quinone reductase subunit A, C-terminal domain GO:0016655|GO:0055114 MC49_RS09705 07b9bc04c8505ba9822f9f47aa2cdea9 447 Hamap MF_00425 Na(+)-translocating NADH-quinone reductase subunit A [nqrA]. 1 447 45.317 T 29-03-2018 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 MC49_RS09705 07b9bc04c8505ba9822f9f47aa2cdea9 447 Pfam PF05896 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) 1 256 2.6E-112 T 29-03-2018 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 MC49_RS05140 3fd315c0b6de46f8f1238e597e1de208 125 Pfam PF03899 ATP synthase I chain 13 110 2.6E-14 T 29-03-2018 IPR005598 ATP synthase protein I MC49_RS16045 a72e7755f1070abf1bbec96fe822e848 293 Gene3D G3DSA:3.30.2010.10 64 157 2.8E-21 T 29-03-2018 MC49_RS16045 a72e7755f1070abf1bbec96fe822e848 293 Pfam PF01435 Peptidase family M48 73 288 4.2E-41 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 MC49_RS16045 a72e7755f1070abf1bbec96fe822e848 293 Hamap MF_00188 Protease HtpX [htpX]. 1 289 26.264 T 29-03-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 MC49_RS13235 cb822ccc3e1e4f69598baff46719881d 77 SMART SM00671 39 74 4.1E-8 T 29-03-2018 IPR006597 Sel1-like repeat MC49_RS13235 cb822ccc3e1e4f69598baff46719881d 77 SUPERFAMILY SSF81901 30 77 2.49E-9 T 29-03-2018 MC49_RS13235 cb822ccc3e1e4f69598baff46719881d 77 Gene3D G3DSA:2.60.40.1180 14 77 3.3E-12 T 29-03-2018 MC49_RS08160 d088efe294dc60007d1544a5c4381e69 193 Pfam PF13242 HAD-hyrolase-like 107 177 1.4E-12 T 29-03-2018 MC49_RS08160 d088efe294dc60007d1544a5c4381e69 193 TIGRFAM TIGR00213 GmhB_yaeD: D,D-heptose 1,7-bisphosphate phosphatase 4 178 4.7E-87 T 29-03-2018 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 MC49_RS08160 d088efe294dc60007d1544a5c4381e69 193 SUPERFAMILY SSF56784 1 182 2.07E-54 T 29-03-2018 IPR023214 HAD-like domain MC49_RS08160 d088efe294dc60007d1544a5c4381e69 193 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 5 149 1.5E-37 T 29-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 MC49_RS08160 d088efe294dc60007d1544a5c4381e69 193 Gene3D G3DSA:3.40.50.1000 2 189 5.0E-32 T 29-03-2018 IPR023214 HAD-like domain MC49_RS08160 d088efe294dc60007d1544a5c4381e69 193 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 4 153 3.9E-42 T 29-03-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 MC49_RS08160 d088efe294dc60007d1544a5c4381e69 193 PIRSF PIRSF004682 1 189 9.9E-69 T 29-03-2018 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 MC49_RS10215 b94eb05ac3704ec2a9a4054dff391321 360 Gene3D G3DSA:3.40.50.300 122 329 8.1E-29 T 29-03-2018 MC49_RS10215 b94eb05ac3704ec2a9a4054dff391321 360 Pfam PF02562 PhoH-like protein 126 329 5.6E-94 T 29-03-2018 IPR003714 PhoH-like protein GO:0005524 MC49_RS10215 b94eb05ac3704ec2a9a4054dff391321 360 SUPERFAMILY SSF52540 125 306 5.01E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS19005 0c75d39acb41ff3b02a1eb940c0f91ad 374 Pfam PF12698 ABC-2 family transporter protein 25 364 1.0E-32 T 29-03-2018 MC49_RS19005 0c75d39acb41ff3b02a1eb940c0f91ad 374 Gene3D G3DSA:3.40.1710.10 41 190 1.4E-20 T 29-03-2018 MC49_RS06090 1257901afa0298e2700cd5b3e0463a79 112 Pfam PF07119 Protein of unknown function (DUF1375) 15 76 1.6E-13 T 29-03-2018 IPR010780 Protein of unknown function DUF1375 MC49_RS10545 78c120686961f094c493c3392b7f5d17 231 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 11 220 8.9E-74 T 29-03-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 MC49_RS10545 78c120686961f094c493c3392b7f5d17 231 SUPERFAMILY SSF161098 4 218 6.41E-51 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS10545 78c120686961f094c493c3392b7f5d17 231 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 25 225 5.6E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS10545 78c120686961f094c493c3392b7f5d17 231 Gene3D G3DSA:1.10.3720.10 2 227 9.8E-38 T 29-03-2018 MC49_RS03790 3e3facf1571d37082138340de8afaeba 362 Pfam PF07429 4-alpha-L-fucosyltransferase glycosyl transferase group 56 1 358 5.7E-181 T 29-03-2018 IPR009993 TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase GO:0008417|GO:0009246|GO:0036065 MC49_RS03790 3e3facf1571d37082138340de8afaeba 362 Hamap MF_01002 TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase [wecF]. 1 362 63.859 T 29-03-2018 IPR009993 TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase GO:0008417|GO:0009246|GO:0036065 MC49_RS03790 3e3facf1571d37082138340de8afaeba 362 Gene3D G3DSA:3.40.50.2000 188 355 4.7E-4 T 29-03-2018 MC49_RS13030 f05bf324b41c885ece4db900c75a5bd7 63 Pfam PF16080 Bacteriophage holin family HP1 5 59 6.3E-29 T 29-03-2018 IPR032118 Bacteriophage holin HP1 family MC49_RS02455 ed2f841fe5b1bde44a05a5fe026726f3 175 Gene3D G3DSA:2.60.40.1090 29 175 3.4E-33 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS02455 ed2f841fe5b1bde44a05a5fe026726f3 175 SUPERFAMILY SSF49401 30 175 4.62E-37 T 29-03-2018 IPR008966 Adhesion domain MC49_RS02455 ed2f841fe5b1bde44a05a5fe026726f3 175 Pfam PF00419 Fimbrial protein 32 175 8.4E-20 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS04915 0ad2d385d866cc7bd72e03e52d6004dc 120 Pfam PF10928 Protein of unknown function (DUF2810) 66 117 8.7E-31 T 29-03-2018 IPR021230 Protein of unknown function DUF2810 MC49_RS10325 23c0a9b3c12bb2228e0214e0108ba63c 142 Pfam PF00892 EamA-like transporter family 4 140 3.0E-22 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MC49_RS10325 23c0a9b3c12bb2228e0214e0108ba63c 142 SUPERFAMILY SSF103481 38 141 7.32E-15 T 29-03-2018 MC49_RS06335 e6634b19a8710e0214209dd8eae60f8d 67 Pfam PF09526 Probable metal-binding protein (DUF2387) 4 58 1.8E-20 T 29-03-2018 IPR012658 Conserved hypothetical protein CHP02443 MC49_RS06335 e6634b19a8710e0214209dd8eae60f8d 67 TIGRFAM TIGR02443 TIGR02443: conserved hypothetical protein 3 60 3.1E-29 T 29-03-2018 IPR012658 Conserved hypothetical protein CHP02443 MC49_RS06335 e6634b19a8710e0214209dd8eae60f8d 67 Gene3D G3DSA:2.20.25.10 11 51 2.8E-4 T 29-03-2018 MC49_RS10340 09b5cf1d8d992574642f26770129583d 381 Gene3D G3DSA:1.20.1250.20 195 371 3.6E-8 T 29-03-2018 MC49_RS10340 09b5cf1d8d992574642f26770129583d 381 SUPERFAMILY SSF103473 5 369 3.79E-48 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS10340 09b5cf1d8d992574642f26770129583d 381 Pfam PF07690 Major Facilitator Superfamily 20 341 1.1E-35 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS10340 09b5cf1d8d992574642f26770129583d 381 Gene3D G3DSA:1.20.1250.20 2 194 5.9E-29 T 29-03-2018 MC49_RS10340 09b5cf1d8d992574642f26770129583d 381 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 7 343 1.8E-60 T 29-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 MC49_RS18865 c32dcaac81407f6597703ed21e060396 136 Pfam PF04143 Sulphur transport 13 129 5.4E-8 T 29-03-2018 IPR007272 Sulphur transport domain MC49_RS09625 3770d47c5d28c6dec71bb62f40e535a8 140 Gene3D G3DSA:3.30.420.140 2 139 2.2E-39 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 MC49_RS09625 3770d47c5d28c6dec71bb62f40e535a8 140 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 7 136 9.8E-52 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 MC49_RS09625 3770d47c5d28c6dec71bb62f40e535a8 140 SUPERFAMILY SSF53098 4 137 8.65E-41 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MC49_RS09625 3770d47c5d28c6dec71bb62f40e535a8 140 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 4 139 24.793 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 MC49_RS09625 3770d47c5d28c6dec71bb62f40e535a8 140 SMART SM00732 4 104 4.0E-34 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 MC49_RS09625 3770d47c5d28c6dec71bb62f40e535a8 140 Pfam PF03652 Holliday junction resolvase 5 136 3.2E-40 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 MC49_RS07170 7903a1f6580daca4d44ef4092c153325 483 Pfam PF02386 Cation transport protein 36 475 2.2E-87 T 29-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 MC49_RS07170 7903a1f6580daca4d44ef4092c153325 483 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 84 466 2.7E-124 T 29-03-2018 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 MC49_RS07170 7903a1f6580daca4d44ef4092c153325 483 PIRSF PIRSF006247 1 483 4.9E-183 T 29-03-2018 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 MC49_RS15230 a097f086477d8f7dcbe743c17d2cab8a 457 Gene3D G3DSA:3.40.50.300 221 452 4.4E-44 T 29-03-2018 MC49_RS15230 a097f086477d8f7dcbe743c17d2cab8a 457 Pfam PF00271 Helicase conserved C-terminal domain 228 336 1.5E-29 T 29-03-2018 IPR001650 Helicase, C-terminal MC49_RS15230 a097f086477d8f7dcbe743c17d2cab8a 457 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 151 159 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site MC49_RS15230 a097f086477d8f7dcbe743c17d2cab8a 457 Pfam PF00270 DEAD/DEAH box helicase 27 191 2.0E-45 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MC49_RS15230 a097f086477d8f7dcbe743c17d2cab8a 457 SUPERFAMILY SSF52540 73 351 1.11E-73 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS15230 a097f086477d8f7dcbe743c17d2cab8a 457 Gene3D G3DSA:3.40.50.300 5 220 2.6E-60 T 29-03-2018 MC49_RS15230 a097f086477d8f7dcbe743c17d2cab8a 457 Pfam PF03880 DbpA RNA binding domain 384 454 2.1E-22 T 29-03-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain MC49_RS15230 a097f086477d8f7dcbe743c17d2cab8a 457 SMART SM00490 255 336 2.0E-30 T 29-03-2018 IPR001650 Helicase, C-terminal MC49_RS15230 a097f086477d8f7dcbe743c17d2cab8a 457 SMART SM00487 22 219 7.4E-60 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MC49_RS15230 a097f086477d8f7dcbe743c17d2cab8a 457 Hamap MF_00965 ATP-dependent RNA helicase DbpA [dbpA]. 5 457 66.528 T 29-03-2018 IPR028619 ATP-dependent RNA helicase DbpA GO:0000027|GO:0003724 MC49_RS03645 d73e1224643f49c0d375275c5847db6a 349 SUPERFAMILY SSF52540 113 339 1.7E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS03645 d73e1224643f49c0d375275c5847db6a 349 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 72 333 1.4E-91 T 29-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 MC49_RS03645 d73e1224643f49c0d375275c5847db6a 349 Gene3D G3DSA:2.40.50.140 34 101 7.8E-19 T 29-03-2018 MC49_RS03645 d73e1224643f49c0d375275c5847db6a 349 Gene3D G3DSA:1.10.40.50 276 343 4.7E-23 T 29-03-2018 MC49_RS03645 d73e1224643f49c0d375275c5847db6a 349 Gene3D G3DSA:3.40.50.300 115 274 9.9E-25 T 29-03-2018 MC49_RS03645 d73e1224643f49c0d375275c5847db6a 349 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 39 339 37.678 T 29-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 MC49_RS03645 d73e1224643f49c0d375275c5847db6a 349 Pfam PF03193 RsgA GTPase 99 275 1.5E-56 T 29-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 MC49_RS04900 0cecb6ccf00eaa8370e74eb5bca7cd24 110 Pfam PF06755 CbtA_toxin of type IV toxin-antitoxin system 8 98 4.0E-36 T 29-03-2018 IPR009610 CbtA toxin of type IV toxin-antitoxin system MC49_RS06765 6806ddde98d65b0dee56584bf1ce9060 294 SUPERFAMILY SSF46785 34 69 5.36E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS06765 6806ddde98d65b0dee56584bf1ce9060 294 Pfam PF13730 Helix-turn-helix domain 19 67 1.2E-10 T 29-03-2018 MC49_RS06765 6806ddde98d65b0dee56584bf1ce9060 294 Gene3D G3DSA:1.10.10.10 7 75 4.6E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS12715 85a057c1c6ebadaceb1ccdd72d0b7bd4 170 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 91 168 2.7E-9 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 MC49_RS12715 85a057c1c6ebadaceb1ccdd72d0b7bd4 170 TIGRFAM TIGR03823 FliZ: flagellar regulatory protein FliZ 1 167 4.8E-88 T 29-03-2018 IPR022523 Flagellar regulator, FliZ MC49_RS12715 85a057c1c6ebadaceb1ccdd72d0b7bd4 170 Gene3D G3DSA:1.10.150.130 84 169 2.6E-4 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal MC49_RS06995 e835780c920f54f0980d3e8ef87a124b 398 Gene3D G3DSA:3.90.1150.10 1 75 1.6E-11 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS06995 e835780c920f54f0980d3e8ef87a124b 398 Gene3D G3DSA:3.90.1150.10 289 398 1.8E-27 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS06995 e835780c920f54f0980d3e8ef87a124b 398 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 244 257 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 MC49_RS06995 e835780c920f54f0980d3e8ef87a124b 398 Pfam PF00155 Aminotransferase class I and II 27 392 7.1E-82 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MC49_RS06995 e835780c920f54f0980d3e8ef87a124b 398 SUPERFAMILY SSF53383 1 394 2.5E-115 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS06995 e835780c920f54f0980d3e8ef87a124b 398 Gene3D G3DSA:3.40.640.10 76 288 1.9E-28 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS06995 e835780c920f54f0980d3e8ef87a124b 398 PRINTS PR00799 Aspartate aminotransferase signature 274 299 2.4E-34 T 29-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 MC49_RS06995 e835780c920f54f0980d3e8ef87a124b 398 PRINTS PR00799 Aspartate aminotransferase signature 176 195 2.4E-34 T 29-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 MC49_RS06995 e835780c920f54f0980d3e8ef87a124b 398 PRINTS PR00799 Aspartate aminotransferase signature 342 360 2.4E-34 T 29-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 MC49_RS06995 e835780c920f54f0980d3e8ef87a124b 398 PRINTS PR00799 Aspartate aminotransferase signature 207 219 2.4E-34 T 29-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 MC49_RS10075 91b96fe6667e85c81d22fe4fafb2a2c5 282 SUPERFAMILY SSF103481 41 136 7.32E-12 T 29-03-2018 MC49_RS10075 91b96fe6667e85c81d22fe4fafb2a2c5 282 SUPERFAMILY SSF103481 177 279 2.88E-14 T 29-03-2018 MC49_RS10075 91b96fe6667e85c81d22fe4fafb2a2c5 282 Pfam PF00892 EamA-like transporter family 7 133 2.8E-13 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MC49_RS10075 91b96fe6667e85c81d22fe4fafb2a2c5 282 Pfam PF00892 EamA-like transporter family 143 275 5.3E-23 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MC49_RS10455 2745e75b97388cd1d096dc812b0d1280 430 Pfam PF04052 TolB amino-terminal domain 23 122 8.3E-31 T 29-03-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 MC49_RS10455 2745e75b97388cd1d096dc812b0d1280 430 SUPERFAMILY SSF69304 155 428 4.97E-54 T 29-03-2018 MC49_RS10455 2745e75b97388cd1d096dc812b0d1280 430 Gene3D G3DSA:2.130.10.10 170 279 7.5E-19 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MC49_RS10455 2745e75b97388cd1d096dc812b0d1280 430 Gene3D G3DSA:2.140.10.30 280 413 7.4E-22 T 29-03-2018 MC49_RS10455 2745e75b97388cd1d096dc812b0d1280 430 Pfam PF07676 WD40-like Beta Propeller Repeat 199 223 1.2E-4 T 29-03-2018 IPR011659 WD40-like Beta Propeller MC49_RS10455 2745e75b97388cd1d096dc812b0d1280 430 Pfam PF07676 WD40-like Beta Propeller Repeat 371 396 0.038 T 29-03-2018 IPR011659 WD40-like Beta Propeller MC49_RS10455 2745e75b97388cd1d096dc812b0d1280 430 Pfam PF07676 WD40-like Beta Propeller Repeat 280 315 1.3E-11 T 29-03-2018 IPR011659 WD40-like Beta Propeller MC49_RS10455 2745e75b97388cd1d096dc812b0d1280 430 Pfam PF07676 WD40-like Beta Propeller Repeat 237 272 1.8E-9 T 29-03-2018 IPR011659 WD40-like Beta Propeller MC49_RS10455 2745e75b97388cd1d096dc812b0d1280 430 Gene3D G3DSA:3.40.50.10070 22 164 7.8E-38 T 29-03-2018 MC49_RS10455 2745e75b97388cd1d096dc812b0d1280 430 Hamap MF_00671 Protein TolB [tolB]. 8 426 34.023 T 29-03-2018 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 MC49_RS10455 2745e75b97388cd1d096dc812b0d1280 430 TIGRFAM TIGR02800 propeller_TolB: Tol-Pal system beta propeller repeat protein TolB 14 427 4.6E-158 T 29-03-2018 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 MC49_RS10455 2745e75b97388cd1d096dc812b0d1280 430 SUPERFAMILY SSF52964 28 161 1.44E-39 T 29-03-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 MC49_RS01410 1b5f27d1e033fa81ac59d55aed3318e4 196 SUPERFAMILY SSF53697 2 191 2.43E-49 T 29-03-2018 MC49_RS01410 1b5f27d1e033fa81ac59d55aed3318e4 196 Gene3D G3DSA:3.40.50.10490 1 196 1.7E-34 T 29-03-2018 MC49_RS01410 1b5f27d1e033fa81ac59d55aed3318e4 196 Pfam PF13580 SIS domain 9 144 2.4E-33 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MC49_RS10635 92226f1434eeb052df6cba6f6bc7f102 295 Gene3D G3DSA:1.10.510.10 57 289 5.5E-22 T 29-03-2018 MC49_RS10635 92226f1434eeb052df6cba6f6bc7f102 295 Pfam PF01636 Phosphotransferase enzyme family 33 247 3.2E-35 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase MC49_RS10635 92226f1434eeb052df6cba6f6bc7f102 295 SUPERFAMILY SSF56112 15 265 1.05E-47 T 29-03-2018 IPR011009 Protein kinase-like domain MC49_RS11390 cdcab05e07d36d611bf5cfb4bf3b09d0 75 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 6 30 - T 29-03-2018 IPR001455 TusA-like domain MC49_RS11390 cdcab05e07d36d611bf5cfb4bf3b09d0 75 Pfam PF01206 Sulfurtransferase TusA 5 74 3.4E-22 T 29-03-2018 IPR001455 TusA-like domain MC49_RS11390 cdcab05e07d36d611bf5cfb4bf3b09d0 75 SUPERFAMILY SSF64307 3 75 7.98E-25 T 29-03-2018 IPR001455 TusA-like domain MC49_RS11390 cdcab05e07d36d611bf5cfb4bf3b09d0 75 Gene3D G3DSA:3.30.110.40 1 75 2.2E-21 T 29-03-2018 IPR001455 TusA-like domain MC49_RS04285 ff0aee39da8467882c64990846e9647c 214 SUPERFAMILY SSF52540 4 208 1.15E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS04285 ff0aee39da8467882c64990846e9647c 214 SMART SM00382 32 209 1.9E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS04285 ff0aee39da8467882c64990846e9647c 214 Gene3D G3DSA:3.40.50.300 3 210 6.0E-45 T 29-03-2018 MC49_RS04285 ff0aee39da8467882c64990846e9647c 214 Pfam PF00005 ABC transporter 24 169 1.3E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MC49_RS04175 499a35b95dd0ec7c8338fe99fb0481cc 63 Pfam PF04324 BFD-like [2Fe-2S] binding domain 2 52 7.4E-14 T 29-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain MC49_RS05695 434bace3428b76dd64b6d8a82d3f1889 368 TIGRFAM TIGR03573 WbuX: N-acetyl sugar amidotransferase 1 346 1.1E-132 T 29-03-2018 IPR020022 N-acetyl sugar amidotransferase MC49_RS05695 434bace3428b76dd64b6d8a82d3f1889 368 SUPERFAMILY SSF52402 16 168 1.52E-15 T 29-03-2018 MC49_RS05695 434bace3428b76dd64b6d8a82d3f1889 368 Gene3D G3DSA:3.40.50.620 50 365 1.2E-11 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS16870 26ca148e613055897243f985d29a510b 102 Pfam PF11287 Protein of unknown function (DUF3088) 2 79 4.2E-30 T 29-03-2018 IPR021439 Protein of unknown function DUF3088 MC49_RS16870 26ca148e613055897243f985d29a510b 102 SUPERFAMILY SSF52833 22 82 3.66E-5 T 29-03-2018 IPR012336 Thioredoxin-like fold MC49_RS17020 65031d9fba8575582aaa16a2aa9c531f 389 Gene3D G3DSA:3.90.1150.10 307 384 9.1E-14 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 MC49_RS17020 65031d9fba8575582aaa16a2aa9c531f 389 Pfam PF00155 Aminotransferase class I and II 48 379 1.1E-39 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MC49_RS17020 65031d9fba8575582aaa16a2aa9c531f 389 SUPERFAMILY SSF53383 31 383 3.73E-64 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase MC49_RS17020 65031d9fba8575582aaa16a2aa9c531f 389 Gene3D G3DSA:3.40.640.10 57 306 8.1E-34 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 MC49_RS07175 878691434c41f62ba3bd11c35ab3d1a1 174 Gene3D G3DSA:3.40.50.360 3 174 2.5E-16 T 29-03-2018 IPR029039 Flavoprotein-like domain MC49_RS07175 878691434c41f62ba3bd11c35ab3d1a1 174 SUPERFAMILY SSF52218 1 172 1.29E-27 T 29-03-2018 IPR029039 Flavoprotein-like domain MC49_RS07175 878691434c41f62ba3bd11c35ab3d1a1 174 Pfam PF12724 Flavodoxin domain 4 152 5.5E-50 T 29-03-2018 IPR026816 Flavodoxin domain MC49_RS09390 c6886ad40f43d16ff1cbc3e303bd1bf2 380 Hamap MF_01559 L-lactate dehydrogenase [lldD]. 1 380 74.774 T 29-03-2018 IPR020920 L-lactate dehydrogenase, bacterial GO:0004457|GO:0006089|GO:0010181|GO:0055114 MC49_RS09390 c6886ad40f43d16ff1cbc3e303bd1bf2 380 Pfam PF01070 FMN-dependent dehydrogenase 13 375 1.7E-128 T 29-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 MC49_RS09390 c6886ad40f43d16ff1cbc3e303bd1bf2 380 Gene3D G3DSA:3.20.20.70 2 378 5.9E-98 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS09390 c6886ad40f43d16ff1cbc3e303bd1bf2 380 PIRSF PIRSF000138 2 379 1.7E-123 T 29-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 MC49_RS09390 c6886ad40f43d16ff1cbc3e303bd1bf2 380 SUPERFAMILY SSF51395 7 376 2.87E-101 T 29-03-2018 MC49_RS09390 c6886ad40f43d16ff1cbc3e303bd1bf2 380 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 273 279 - T 29-03-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 MC49_RS11880 14cc83ab8b5b6eb9f0e07072dd885f54 577 Pfam PF05947 Type VI secretion system, TssF 6 565 8.6E-56 T 29-03-2018 IPR010272 Type VI secretion system, TssF-like MC49_RS14650 1ea47b32d243e6901b8b41b2e5d3c9fc 163 Pfam PF13671 AAA domain 10 151 2.5E-26 T 29-03-2018 MC49_RS14650 1ea47b32d243e6901b8b41b2e5d3c9fc 163 Gene3D G3DSA:3.40.50.300 8 157 1.2E-14 T 29-03-2018 MC49_RS14650 1ea47b32d243e6901b8b41b2e5d3c9fc 163 SUPERFAMILY SSF52540 10 130 1.31E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS04265 19e4d452714c71bfc4fe225b3811c33a 229 Pfam PF10670 Domain of unknown function (DUF4198) 20 197 4.2E-15 T 29-03-2018 IPR019613 Protein of unknown function DUF4198 MC49_RS11935 37ea6236b42caf1ffc1d4882b94fa8aa 422 Gene3D G3DSA:2.60.200.20 14 116 3.4E-9 T 29-03-2018 MC49_RS11935 37ea6236b42caf1ffc1d4882b94fa8aa 422 TIGRFAM TIGR03354 VI_FHA: type VI secretion system FHA domain protein 8 419 1.9E-100 T 29-03-2018 IPR017735 Type VI secretion system, FHA domain-containing protein MC49_RS11935 37ea6236b42caf1ffc1d4882b94fa8aa 422 SUPERFAMILY SSF49879 28 103 6.78E-8 T 29-03-2018 IPR008984 SMAD/FHA domain GO:0005515 MC49_RS11935 37ea6236b42caf1ffc1d4882b94fa8aa 422 Pfam PF00498 FHA domain 32 98 1.5E-4 T 29-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 MC49_RS17835 9bb6f7214abdbeacd7224593a4e9ee99 340 Gene3D G3DSA:1.10.150.130 57 166 1.8E-21 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal MC49_RS17835 9bb6f7214abdbeacd7224593a4e9ee99 340 SUPERFAMILY SSF56349 62 325 6.18E-52 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MC49_RS17835 9bb6f7214abdbeacd7224593a4e9ee99 340 Pfam PF00589 Phage integrase family 165 325 1.3E-10 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MC49_RS17835 9bb6f7214abdbeacd7224593a4e9ee99 340 Gene3D G3DSA:1.10.443.10 167 328 7.7E-17 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MC49_RS12285 ae43c930dd71ed9458b9bfc7988acf38 128 Pfam PF03692 Putative zinc- or iron-chelating domain 14 105 2.0E-10 T 29-03-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein MC49_RS18130 7fe853814bf682b11920fb502deca7ee 161 Pfam PF16103 Domain of unknown function (DUF4822) 44 160 6.7E-17 T 29-03-2018 IPR032247 Domain of unknown function DUF4822 MC49_RS01555 68fed17f50a59fa7b43184190359ade0 319 Pfam PF01699 Sodium/calcium exchanger protein 6 135 1.8E-22 T 29-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 MC49_RS01555 68fed17f50a59fa7b43184190359ade0 319 Pfam PF01699 Sodium/calcium exchanger protein 175 314 4.2E-24 T 29-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 MC49_RS01555 68fed17f50a59fa7b43184190359ade0 319 TIGRFAM TIGR00367 TIGR00367: K+-dependent Na+/Ca+ exchanger homolog 2 312 5.7E-73 T 29-03-2018 IPR004481 Sodium/potassium/calcium exchanger Reactome: R-HSA-425561 MC49_RS06885 0abe901963528eba3e0304ee52c87335 132 TIGRFAM TIGR01674 phage_lambda_G: phage minor tail protein G 3 124 1.4E-22 T 29-03-2018 IPR010027 Bacteriophage lambda, GpG, minor tail MC49_RS06885 0abe901963528eba3e0304ee52c87335 132 Pfam PF06894 Bacteriophage lambda tail assembly chaperone, TAC, protein G 3 115 1.1E-24 T 29-03-2018 IPR010027 Bacteriophage lambda, GpG, minor tail MC49_RS05805 8d41f0ebcc602e01884262697d80abfb 206 Pfam PF07305 Protein of unknown function (DUF1454) 12 201 8.7E-72 T 29-03-2018 IPR009918 Protein of unknown function DUF1454 MC49_RS06280 765398663c9c6bc16dc8a5ed4a85fc70 135 Gene3D G3DSA:2.20.25.10 1 29 4.2E-16 T 29-03-2018 MC49_RS06280 765398663c9c6bc16dc8a5ed4a85fc70 135 SUPERFAMILY SSF82784 1 131 5.23E-41 T 29-03-2018 IPR003718 OsmC/Ohr family MC49_RS06280 765398663c9c6bc16dc8a5ed4a85fc70 135 Pfam PF02566 OsmC-like protein 31 127 3.5E-18 T 29-03-2018 IPR003718 OsmC/Ohr family MC49_RS06280 765398663c9c6bc16dc8a5ed4a85fc70 135 Gene3D G3DSA:3.30.300.20 34 135 1.4E-19 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta MC49_RS07085 37e3901dea5b1a2e7e91cfeaa263b830 260 Pfam PF13350 Tyrosine phosphatase family 13 260 2.4E-55 T 29-03-2018 IPR026893 Tyrosine/serine-protein phosphatase IphP-type MC49_RS07085 37e3901dea5b1a2e7e91cfeaa263b830 260 SUPERFAMILY SSF52799 12 259 7.28E-48 T 29-03-2018 IPR029021 Protein-tyrosine phosphatase-like MC49_RS07085 37e3901dea5b1a2e7e91cfeaa263b830 260 Gene3D G3DSA:3.90.190.10 26 203 1.3E-16 T 29-03-2018 IPR029021 Protein-tyrosine phosphatase-like MC49_RS03060 f0894c9b7c5278c87c600cce414f1dee 93 Gene3D G3DSA:3.40.50.2300 1 92 4.6E-16 T 29-03-2018 MC49_RS03060 f0894c9b7c5278c87c600cce414f1dee 93 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 71 1.3E-14 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 MC49_RS03060 f0894c9b7c5278c87c600cce414f1dee 93 SUPERFAMILY SSF52794 1 88 3.79E-19 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 MC49_RS15545 44f9a3415fd2a04e25074c52d9d1e491 113 Gene3D G3DSA:1.10.260.40 1 108 8.8E-19 T 29-03-2018 MC49_RS15545 44f9a3415fd2a04e25074c52d9d1e491 113 SUPERFAMILY SSF47413 4 78 1.18E-19 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS15545 44f9a3415fd2a04e25074c52d9d1e491 113 Pfam PF01381 Helix-turn-helix 15 65 3.0E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS15545 44f9a3415fd2a04e25074c52d9d1e491 113 SMART SM00530 13 68 8.0E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS13140 85ef6f01971677ba5ae7ee49f6117f3a 188 Pfam PF06805 Bacteriophage lambda tail assembly protein I 7 84 1.2E-8 T 29-03-2018 IPR010654 Bacteriophage lambda tail assembly I MC49_RS13140 85ef6f01971677ba5ae7ee49f6117f3a 188 SUPERFAMILY SSF54285 5 83 2.62E-5 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp MC49_RS19045 54fdeae4240daaaaa4f1b5957b583124 294 Gene3D G3DSA:1.20.1000.10 23 189 5.0E-5 T 29-03-2018 MC49_RS19045 54fdeae4240daaaaa4f1b5957b583124 294 Pfam PF10979 Protein of unknown function (DUF2786) 68 104 1.5E-10 T 29-03-2018 IPR024498 Domain of unknown function DUF2786 MC49_RS01365 5ba88e4e580fed88ee9366dff25c4394 100 Pfam PF13997 YqjK-like protein 16 88 2.4E-25 T 29-03-2018 IPR025612 YqjK-like protein MC49_RS05485 6c3a8b1f91274408401f368d27e43648 147 Pfam PF04214 Protein of unknown function, DUF 58 121 9.1E-18 T 29-03-2018 IPR007332 Protein of unknown function DUF411 MC49_RS05485 6c3a8b1f91274408401f368d27e43648 147 Gene3D G3DSA:3.40.30.10 9 107 0.0011 T 29-03-2018 MC49_RS01900 13df1d710881cb7fe312669fdb519340 222 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 12 204 6.4E-63 T 29-03-2018 IPR003744 Queuosine precursor transporter MC49_RS01900 13df1d710881cb7fe312669fdb519340 222 Pfam PF02592 Putative vitamin uptake transporter 43 198 2.0E-33 T 29-03-2018 IPR003744 Queuosine precursor transporter MC49_RS14810 1cf4c8b6dd866ebf44427d5c303228b4 134 SUPERFAMILY SSF55811 10 117 4.33E-18 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 MC49_RS14810 1cf4c8b6dd866ebf44427d5c303228b4 134 ProSitePatterns PS00893 Nudix box signature. 35 56 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MC49_RS14810 1cf4c8b6dd866ebf44427d5c303228b4 134 Pfam PF00293 NUDIX domain 10 113 3.0E-11 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MC49_RS14810 1cf4c8b6dd866ebf44427d5c303228b4 134 Gene3D G3DSA:3.90.79.10 8 130 3.8E-15 T 29-03-2018 MC49_RS02595 a9feebf91460e2a33fb48c8216dfaa86 318 SUPERFAMILY SSF53613 11 314 2.49E-48 T 29-03-2018 IPR029056 Ribokinase-like MC49_RS02595 a9feebf91460e2a33fb48c8216dfaa86 318 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 259 272 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MC49_RS02595 a9feebf91460e2a33fb48c8216dfaa86 318 Pfam PF00294 pfkB family carbohydrate kinase 12 302 2.2E-40 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB MC49_RS02595 a9feebf91460e2a33fb48c8216dfaa86 318 Gene3D G3DSA:3.40.1190.20 8 318 3.1E-48 T 29-03-2018 IPR029056 Ribokinase-like MC49_RS08510 ff0818a4ce3b7c1e412a85a285f3384c 431 SUPERFAMILY SSF118215 6 404 2.62E-109 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MC49_RS08510 ff0818a4ce3b7c1e412a85a285f3384c 431 PRINTS PR00173 Glutamate-aspartate symporter signature 50 70 4.7E-40 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MC49_RS08510 ff0818a4ce3b7c1e412a85a285f3384c 431 PRINTS PR00173 Glutamate-aspartate symporter signature 195 214 4.7E-40 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MC49_RS08510 ff0818a4ce3b7c1e412a85a285f3384c 431 PRINTS PR00173 Glutamate-aspartate symporter signature 80 105 4.7E-40 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MC49_RS08510 ff0818a4ce3b7c1e412a85a285f3384c 431 PRINTS PR00173 Glutamate-aspartate symporter signature 357 377 4.7E-40 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MC49_RS08510 ff0818a4ce3b7c1e412a85a285f3384c 431 PRINTS PR00173 Glutamate-aspartate symporter signature 148 170 4.7E-40 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MC49_RS08510 ff0818a4ce3b7c1e412a85a285f3384c 431 PRINTS PR00173 Glutamate-aspartate symporter signature 330 349 4.7E-40 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MC49_RS08510 ff0818a4ce3b7c1e412a85a285f3384c 431 PRINTS PR00173 Glutamate-aspartate symporter signature 4 24 4.7E-40 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MC49_RS08510 ff0818a4ce3b7c1e412a85a285f3384c 431 PRINTS PR00173 Glutamate-aspartate symporter signature 295 321 4.7E-40 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MC49_RS08510 ff0818a4ce3b7c1e412a85a285f3384c 431 Gene3D G3DSA:1.10.3860.10 1 409 7.4E-113 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MC49_RS08510 ff0818a4ce3b7c1e412a85a285f3384c 431 Pfam PF00375 Sodium:dicarboxylate symporter family 6 403 1.7E-105 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MC49_RS02090 7cac4cf0a9d4b4d8e49c9096e6b2e967 260 SUPERFAMILY SSF53335 51 169 1.15E-29 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS02090 7cac4cf0a9d4b4d8e49c9096e6b2e967 260 SUPERFAMILY SSF53335 198 241 1.15E-29 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS02090 7cac4cf0a9d4b4d8e49c9096e6b2e967 260 Gene3D G3DSA:3.40.50.150 4 243 2.7E-23 T 29-03-2018 MC49_RS02090 7cac4cf0a9d4b4d8e49c9096e6b2e967 260 Pfam PF08241 Methyltransferase domain 63 157 1.8E-14 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 MC49_RS17530 f28db93126887634f18ef11441eba3ad 363 Pfam PF05954 Phage late control gene D protein (GPD) 61 333 2.4E-23 T 29-03-2018 MC49_RS17530 f28db93126887634f18ef11441eba3ad 363 Gene3D G3DSA:3.55.50.10 111 196 1.6E-4 T 29-03-2018 MC49_RS17530 f28db93126887634f18ef11441eba3ad 363 SUPERFAMILY SSF69279 21 186 2.38E-26 T 29-03-2018 MC49_RS07755 2872a2f198bcaf28f3b0b4008d06f9ca 248 Gene3D G3DSA:3.40.1130.10 30 248 5.5E-42 T 29-03-2018 MC49_RS07755 2872a2f198bcaf28f3b0b4008d06f9ca 248 SMART SM00563 67 182 4.4E-40 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MC49_RS07755 2872a2f198bcaf28f3b0b4008d06f9ca 248 SUPERFAMILY SSF69593 8 241 3.66E-60 T 29-03-2018 MC49_RS07755 2872a2f198bcaf28f3b0b4008d06f9ca 248 Pfam PF01553 Acyltransferase 58 180 4.6E-31 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 MC49_RS07755 2872a2f198bcaf28f3b0b4008d06f9ca 248 TIGRFAM TIGR00530 AGP_acyltrn: 1-acylglycerol-3-phosphate O-acyltransferases 50 180 1.8E-48 T 29-03-2018 IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferase GO:0003841|GO:0008654|GO:0016020 KEGG: 00561+2.3.1.51|KEGG: 00564+2.3.1.51|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7417|MetaCyc: PWY-7587|MetaCyc: PWY-7589|MetaCyc: PWY-7782|Reactome: R-HSA-1483166 MC49_RS00295 c496b938954250f216a7da1f42c7f3ba 102 Pfam PF04448 Protein of unknown function (DUF551) 38 60 1.3E-5 T 29-03-2018 IPR007539 Domain of unknown function DUF551 MC49_RS14605 85cd79e584c868d1f4c7e6fd52cf3131 162 Gene3D G3DSA:3.30.1330.40 25 162 4.6E-22 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like MC49_RS14605 85cd79e584c868d1f4c7e6fd52cf3131 162 SUPERFAMILY SSF55298 32 162 1.46E-22 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like MC49_RS14605 85cd79e584c868d1f4c7e6fd52cf3131 162 Pfam PF01042 Endoribonuclease L-PSP 41 160 1.5E-18 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family MC49_RS02425 0fbbadcb88d221dcf17cf7a259e900b3 181 Gene3D G3DSA:2.60.40.1090 30 181 8.6E-27 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS02425 0fbbadcb88d221dcf17cf7a259e900b3 181 Pfam PF00419 Fimbrial protein 34 180 5.1E-14 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS02425 0fbbadcb88d221dcf17cf7a259e900b3 181 SUPERFAMILY SSF49401 31 181 2.19E-32 T 29-03-2018 IPR008966 Adhesion domain MC49_RS10210 fae697c634a395a491da3087f9b325bd 155 Pfam PF02130 Uncharacterized protein family UPF0054 20 144 7.0E-40 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 MC49_RS10210 fae697c634a395a491da3087f9b325bd 155 Gene3D G3DSA:3.40.390.30 1 155 6.8E-56 T 29-03-2018 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 MC49_RS10210 fae697c634a395a491da3087f9b325bd 155 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 114 124 - T 29-03-2018 IPR020549 Endoribonuclease YbeY, conserved site MC49_RS10210 fae697c634a395a491da3087f9b325bd 155 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 40 145 1.8E-37 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 MC49_RS10210 fae697c634a395a491da3087f9b325bd 155 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 5 148 25.006 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 MC49_RS10210 fae697c634a395a491da3087f9b325bd 155 SUPERFAMILY SSF55486 4 151 2.69E-50 T 29-03-2018 MC49_RS13480 9bcec426c850ea3c9e19d8023e6ac8a5 178 Gene3D G3DSA:1.25.40.10 79 178 1.1E-35 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MC49_RS13480 9bcec426c850ea3c9e19d8023e6ac8a5 178 Gene3D G3DSA:1.20.58.320 1 78 1.2E-24 T 29-03-2018 MC49_RS13480 9bcec426c850ea3c9e19d8023e6ac8a5 178 Pfam PF06041 Bacterial protein of unknown function (DUF924) 6 175 6.3E-61 T 29-03-2018 IPR010323 Protein of unknown function DUF924 MC49_RS13480 9bcec426c850ea3c9e19d8023e6ac8a5 178 SUPERFAMILY SSF48452 3 174 2.69E-67 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MC49_RS01470 279517102fb9e312468fe02e6efe8054 134 Pfam PF06295 Protein of unknown function (DUF1043) 6 127 2.9E-48 T 29-03-2018 IPR009386 Protein of unknown function DUF1043 MC49_RS01470 279517102fb9e312468fe02e6efe8054 134 PIRSF PIRSF006318 1 134 1.2E-49 T 29-03-2018 IPR009386 Protein of unknown function DUF1043 MC49_RS06960 e68b2498a88c67e27c2e17f3b03b9e74 149 Pfam PF06114 IrrE N-terminal-like domain 66 129 7.6E-8 T 29-03-2018 IPR010359 IrrE N-terminal-like domain MC49_RS13805 6c9e04e2adea9995cd3b9d94e5d4780e 446 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 9 437 3.8E-163 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 MC49_RS13805 6c9e04e2adea9995cd3b9d94e5d4780e 446 PIRSF PIRSF006446 2 446 1.9E-211 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 MC49_RS07300 813c96686ee090df5633fe2ee643efbc 166 Pfam PF04972 BON domain 98 159 5.0E-18 T 29-03-2018 IPR007055 BON domain MC49_RS07300 813c96686ee090df5633fe2ee643efbc 166 Gene3D G3DSA:1.20.120.20 32 102 0.0011 T 29-03-2018 MC49_RS04325 65ac61cd7b424e4696c2297d779209c9 359 SUPERFAMILY SSF49401 206 359 2.29E-13 T 29-03-2018 IPR008966 Adhesion domain MC49_RS04325 65ac61cd7b424e4696c2297d779209c9 359 Pfam PF00419 Fimbrial protein 199 358 3.5E-11 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS04325 65ac61cd7b424e4696c2297d779209c9 359 Gene3D G3DSA:2.60.40.1090 205 359 7.4E-18 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS13825 1e0eead2691e56d1f6bceb623beb6215 202 Pfam PF01810 LysE type translocator 17 200 1.4E-29 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MC49_RS05985 5eca73690a0228be58f88a5a600d7a33 490 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 89 216 4.8E-15 T 29-03-2018 MC49_RS15620 9bc991019d751208f54fbb2fae8f9d13 296 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 14 66 8.8E-8 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain MC49_RS15620 9bc991019d751208f54fbb2fae8f9d13 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 295 7.8E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS15620 9bc991019d751208f54fbb2fae8f9d13 296 Gene3D G3DSA:1.10.3720.10 19 285 8.1E-26 T 29-03-2018 MC49_RS15620 9bc991019d751208f54fbb2fae8f9d13 296 SUPERFAMILY SSF161098 90 277 9.16E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS12055 16343e2183860018104a357758665327 259 ProDom PD117379 LIPOPROTEIN YFHG HELIX ALPHA REGULATOR MEMBRANE TRANSCRIPTIONAL FAMILIIY EBP TWO-COMPONENT 10 201 1.0E-54 T 29-03-2018 MC49_RS12055 16343e2183860018104a357758665327 259 Pfam PF13942 YfhG lipoprotein 35 203 2.0E-71 T 29-03-2018 IPR025262 Quorum-sensing regulator protein G MC49_RS00580 371991cb29756c5acc867f0b93451412 436 Gene3D G3DSA:3.40.1190.20 34 433 4.2E-40 T 29-03-2018 IPR029056 Ribokinase-like MC49_RS00580 371991cb29756c5acc867f0b93451412 436 Pfam PF00294 pfkB family carbohydrate kinase 140 296 4.8E-9 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB MC49_RS00580 371991cb29756c5acc867f0b93451412 436 SUPERFAMILY SSF53613 38 307 3.12E-44 T 29-03-2018 IPR029056 Ribokinase-like MC49_RS00580 371991cb29756c5acc867f0b93451412 436 SUPERFAMILY SSF53613 340 418 3.12E-44 T 29-03-2018 IPR029056 Ribokinase-like MC49_RS09415 055e4042208cea033cd8f9efc5b5cc1a 133 Gene3D G3DSA:3.10.450.100 23 133 4.7E-11 T 29-03-2018 MC49_RS09415 055e4042208cea033cd8f9efc5b5cc1a 133 Pfam PF12870 Domain of unknown function (DUF4878) 20 130 7.9E-20 T 29-03-2018 IPR024267 Domain of unknown function (DUF4878) MC49_RS15715 6d2be1de503f8f355878ba4783973186 253 Pfam PF00849 RNA pseudouridylate synthase 46 201 7.2E-28 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS15715 6d2be1de503f8f355878ba4783973186 253 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 84 98 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS15715 6d2be1de503f8f355878ba4783973186 253 SUPERFAMILY SSF55120 38 253 9.6E-59 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MC49_RS15715 6d2be1de503f8f355878ba4783973186 253 Gene3D G3DSA:3.30.2350.10 37 253 1.5E-56 T 29-03-2018 MC49_RS03490 29c241353779cfefbbfc7affdf5f3a54 176 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 66 72 - T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MC49_RS03490 29c241353779cfefbbfc7affdf5f3a54 176 SUPERFAMILY SSF50324 3 173 1.96E-67 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MC49_RS03490 29c241353779cfefbbfc7affdf5f3a54 176 Gene3D G3DSA:3.90.80.10 2 176 1.1E-53 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MC49_RS03490 29c241353779cfefbbfc7affdf5f3a54 176 Pfam PF00719 Inorganic pyrophosphatase 18 172 3.9E-55 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MC49_RS03490 29c241353779cfefbbfc7affdf5f3a54 176 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 14 174 36.927 T 29-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MC49_RS15280 27f0de6eca07921feeaf22163fde4ad1 302 Gene3D G3DSA:1.10.3720.10 28 291 1.3E-39 T 29-03-2018 MC49_RS15280 27f0de6eca07921feeaf22163fde4ad1 302 SUPERFAMILY SSF161098 100 283 5.63E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS15280 27f0de6eca07921feeaf22163fde4ad1 302 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 24 70 2.7E-11 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain MC49_RS15280 27f0de6eca07921feeaf22163fde4ad1 302 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 300 4.5E-28 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS17630 3a898add2853f2c6a2214eccb749855f 142 Pfam PF13262 Protein of unknown function (DUF4054) 11 112 2.1E-21 T 29-03-2018 IPR025127 Protein of unknown function DUF4054 MC49_RS09325 63062bdc779601df258770aaaf963b70 587 Pfam PF01019 Gamma-glutamyltranspeptidase 48 577 1.1E-180 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MC49_RS09325 63062bdc779601df258770aaaf963b70 587 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 33 547 4.9E-172 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MC49_RS09325 63062bdc779601df258770aaaf963b70 587 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 146 165 8.6E-76 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MC49_RS09325 63062bdc779601df258770aaaf963b70 587 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 374 392 8.6E-76 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MC49_RS09325 63062bdc779601df258770aaaf963b70 587 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 245 261 8.6E-76 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MC49_RS09325 63062bdc779601df258770aaaf963b70 587 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 439 454 8.6E-76 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MC49_RS09325 63062bdc779601df258770aaaf963b70 587 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 128 146 8.6E-76 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MC49_RS09325 63062bdc779601df258770aaaf963b70 587 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 463 480 8.6E-76 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MC49_RS09325 63062bdc779601df258770aaaf963b70 587 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 275 294 8.6E-76 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MC49_RS09325 63062bdc779601df258770aaaf963b70 587 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 398 416 8.6E-76 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MC49_RS09325 63062bdc779601df258770aaaf963b70 587 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 55 80 8.6E-76 T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MC49_RS09325 63062bdc779601df258770aaaf963b70 587 ProSitePatterns PS00462 Gamma-glutamyltranspeptidase signature. 374 398 - T 29-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 MC49_RS09325 63062bdc779601df258770aaaf963b70 587 SUPERFAMILY SSF56235 26 578 1.54E-185 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MC49_RS05270 c82790479fc5f94cdf10f741c77fb36a 303 SUPERFAMILY SSF53067 1 299 4.38E-60 T 29-03-2018 MC49_RS05270 c82790479fc5f94cdf10f741c77fb36a 303 Gene3D G3DSA:3.30.420.40 114 302 1.5E-49 T 29-03-2018 MC49_RS05270 c82790479fc5f94cdf10f741c77fb36a 303 Gene3D G3DSA:3.30.420.40 1 113 9.4E-24 T 29-03-2018 MC49_RS05270 c82790479fc5f94cdf10f741c77fb36a 303 Pfam PF00480 ROK family 2 299 5.1E-74 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 MC49_RS05270 c82790479fc5f94cdf10f741c77fb36a 303 ProSitePatterns PS01125 ROK family signature. 130 157 - T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 MC49_RS12755 199aa24507fa07316430bd005878d372 444 PIRSF PIRSF005353 5 444 1.5E-175 T 29-03-2018 IPR026033 Purine permease PbuG-like MC49_RS12755 199aa24507fa07316430bd005878d372 444 Pfam PF00860 Permease family 31 403 6.3E-45 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 MC49_RS13800 af37dbda2226da1f8d290defc6278ab8 335 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 5 324 1.3E-94 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MC49_RS13800 af37dbda2226da1f8d290defc6278ab8 335 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 6 331 3.1E-51 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MC49_RS11285 67ba97613d820e261694330681190982 195 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 46 190 7.5E-31 T 29-03-2018 IPR005586 ABC-type transport auxiliary lipoprotein component MC49_RS11285 67ba97613d820e261694330681190982 195 SUPERFAMILY SSF159594 27 194 1.05E-22 T 29-03-2018 MC49_RS11285 67ba97613d820e261694330681190982 195 Gene3D G3DSA:3.40.50.10610 15 195 2.9E-38 T 29-03-2018 IPR005586 ABC-type transport auxiliary lipoprotein component MC49_RS18500 600fa4b8d8c53bf601b33a53e6d81b52 241 Pfam PF04402 Protein of unknown function (DUF541) 32 237 3.5E-46 T 29-03-2018 IPR007497 Protein of unknown function DUF541 MC49_RS03920 a6c40afc3b223968919a78151b650de7 112 Pfam PF04219 Protein of unknown function, DUF 10 98 2.8E-40 T 29-03-2018 IPR007335 Protein of unknown function DUF413 MC49_RS12305 4a61a80e2c3b55bc8355a36745230126 233 Pfam PF04773 FecR protein 32 116 5.0E-11 T 29-03-2018 IPR006860 FecR protein MC49_RS01910 9b7fcfb41903ca5c617474e3459235ab 222 Pfam PF11769 Protein of unknown function (DUF3313) 21 217 5.9E-42 T 29-03-2018 IPR021747 Protein of unknown function DUF3313 MC49_RS09265 8cfed3d4d69cb486eec6a6c893dbdb86 160 Gene3D G3DSA:1.10.10.10 1 111 2.9E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS14115 37c8ea310ffdd8019bf2d0966dfbfb6b 129 Hamap MF_01598 Spermidine export protein MdtJ [mdtJ]. 1 122 29.582 T 29-03-2018 IPR023740 Spermidine export protein MdtJ GO:0005886|GO:0015606|GO:0015848 MC49_RS14115 37c8ea310ffdd8019bf2d0966dfbfb6b 129 SUPERFAMILY SSF103481 6 105 8.37E-16 T 29-03-2018 MC49_RS14115 37c8ea310ffdd8019bf2d0966dfbfb6b 129 Pfam PF00893 Small Multidrug Resistance protein 3 94 1.8E-22 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 MC49_RS11645 eff23df18ca40405a943feb5ab14e08e 169 Pfam PF10754 Protein of unknown function (DUF2569) 31 168 5.9E-27 T 29-03-2018 IPR019690 Protein of unknown function DUF2569 MC49_RS18320 e699ebec7860ac15a9f5e36433f6ab98 150 Pfam PF04657 Putative inner membrane exporter, YdcZ 7 145 1.2E-30 T 29-03-2018 IPR006750 Putative inner membrane exporter, YdcZ MC49_RS17915 5a044504028809db8430a276c74fb2a2 193 SUPERFAMILY SSF52317 2 183 4.76E-42 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MC49_RS17915 5a044504028809db8430a276c74fb2a2 193 Gene3D G3DSA:3.40.50.880 1 193 5.8E-49 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MC49_RS17915 5a044504028809db8430a276c74fb2a2 193 Pfam PF01965 DJ-1/PfpI family 5 163 1.7E-22 T 29-03-2018 IPR002818 DJ-1/PfpI MC49_RS17770 e81dbea811e479e56db4d5d0caae4de0 190 SUPERFAMILY SSF52540 29 182 4.05E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS17770 e81dbea811e479e56db4d5d0caae4de0 190 Pfam PF01695 IstB-like ATP binding protein 38 169 2.7E-21 T 29-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 MC49_RS17770 e81dbea811e479e56db4d5d0caae4de0 190 Gene3D G3DSA:3.40.50.300 4 176 8.3E-21 T 29-03-2018 MC49_RS17770 e81dbea811e479e56db4d5d0caae4de0 190 SMART SM00382 48 180 4.0E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS06870 ca912ac6d6180fc3cb0f2f3e447dfc98 187 PIRSF PIRSF004395 1 184 3.9E-74 T 29-03-2018 IPR010633 Bacteriophage lambda, GpZ, minor tail MC49_RS06870 ca912ac6d6180fc3cb0f2f3e447dfc98 187 Pfam PF06763 Prophage minor tail protein Z (GPZ) 2 183 4.2E-63 T 29-03-2018 IPR010633 Bacteriophage lambda, GpZ, minor tail MC49_RS16195 4219662ee32e4d72c356b356e99e1383 209 Pfam PF01066 CDP-alcohol phosphatidyltransferase 27 94 7.8E-10 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MC49_RS16020 a6ec7aa6a63b3570b498345c21035df8 287 Gene3D G3DSA:3.30.200.20 9 91 7.7E-14 T 29-03-2018 MC49_RS16020 a6ec7aa6a63b3570b498345c21035df8 287 Pfam PF03881 Fructosamine kinase 1 286 1.1E-109 T 29-03-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 MC49_RS16020 a6ec7aa6a63b3570b498345c21035df8 287 PIRSF PIRSF006221 1 287 1.7E-89 T 29-03-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 MC49_RS16020 a6ec7aa6a63b3570b498345c21035df8 287 SUPERFAMILY SSF56112 5 280 3.15E-41 T 29-03-2018 IPR011009 Protein kinase-like domain MC49_RS16020 a6ec7aa6a63b3570b498345c21035df8 287 Gene3D G3DSA:3.90.1200.10 96 279 2.6E-15 T 29-03-2018 MC49_RS01195 96ad9da2b5155d02c38ee9aa1c65d1b9 116 Pfam PF11171 Protein of unknown function (DUF2958) 5 114 3.7E-42 T 29-03-2018 IPR021341 Protein of unknown function DUF2958 MC49_RS17540 02ac9350bfe54a0562dd18f585d08f72 93 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 10 75 5.5E-14 T 29-03-2018 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 MC49_RS00270 d0ce4ebae4121bfe54e3a02cc1c61514 199 Pfam PF05766 Bacteriophage Lambda NinG protein 2 194 4.5E-75 T 29-03-2018 IPR008713 Bacteriophage lambda NinG MC49_RS16910 f8744532c55f040125f4ef53c5afabef 126 SUPERFAMILY SSF46785 14 118 8.77E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS16910 f8744532c55f040125f4ef53c5afabef 126 Gene3D G3DSA:1.10.10.10 1 126 9.0E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS16910 f8744532c55f040125f4ef53c5afabef 126 Pfam PF01638 HxlR-like helix-turn-helix 29 115 4.3E-31 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type MC49_RS01570 e42784d27056133cfcb76e7f6311c5ad 193 Hamap MF_01915 Lipopolysaccharide export system protein LptC [lptC]. 4 187 26.146 T 29-03-2018 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 MC49_RS01570 e42784d27056133cfcb76e7f6311c5ad 193 PIRSF PIRSF028513 1 188 5.1E-34 T 29-03-2018 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 MC49_RS01570 e42784d27056133cfcb76e7f6311c5ad 193 TIGRFAM TIGR04409 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC 7 184 1.6E-51 T 29-03-2018 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 MC49_RS01570 e42784d27056133cfcb76e7f6311c5ad 193 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 11 185 2.1E-51 T 29-03-2018 IPR010664 Lipopolysaccharide assembly, LptC-related MC49_RS01570 e42784d27056133cfcb76e7f6311c5ad 193 Gene3D G3DSA:2.60.450.10 89 188 2.0E-5 T 29-03-2018 MC49_RS08735 949639206a48b1346c7bff9480d2bf5d 61 SUPERFAMILY SSF48498 8 55 1.56E-5 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal MC49_RS08005 5af27365a96c07ed5e356f41de1398dc 128 Pfam PF11944 Protein of unknown function (DUF3461) 1 125 1.8E-49 T 29-03-2018 IPR020911 Uncharacterised protein family UPF0325 MC49_RS08005 5af27365a96c07ed5e356f41de1398dc 128 Hamap MF_01519 UPF0325 protein YaeH [yaeH]. 1 126 29.501 T 29-03-2018 IPR020911 Uncharacterised protein family UPF0325 MC49_RS08005 5af27365a96c07ed5e356f41de1398dc 128 ProDom PD080106 UPF0325 YAEH STRUCTURAL ECA1027 VV11856 YPTB3007 PBPRA2971 VV2560 VF1965 VC2264 1 125 3.0E-53 T 29-03-2018 IPR020911 Uncharacterised protein family UPF0325 MC49_RS05085 ba57285dfcb31d41243ad30bd22c6a1f 323 Gene3D G3DSA:1.10.3470.10 35 321 3.0E-40 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like MC49_RS05085 ba57285dfcb31d41243ad30bd22c6a1f 323 Pfam PF02653 Branched-chain amino acid transport system / permease component 46 315 4.0E-52 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 MC49_RS05220 b983f02c677e9c34e75b6a8defdac4af 76 Gene3D G3DSA:1.10.260.40 2 74 5.0E-9 T 29-03-2018 MC49_RS05220 b983f02c677e9c34e75b6a8defdac4af 76 SUPERFAMILY SSF47413 1 68 1.16E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS05220 b983f02c677e9c34e75b6a8defdac4af 76 SMART SM00530 5 61 0.0017 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS05220 b983f02c677e9c34e75b6a8defdac4af 76 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 5 67 4.3E-19 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MC49_RS03145 c1a32735101fc7231dcd515acce12ad4 648 SUPERFAMILY SSF52540 6 84 3.17E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS03145 c1a32735101fc7231dcd515acce12ad4 648 SUPERFAMILY SSF52540 308 379 3.17E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS03145 c1a32735101fc7231dcd515acce12ad4 648 SUPERFAMILY SSF52540 153 233 3.17E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS03145 c1a32735101fc7231dcd515acce12ad4 648 Pfam PF07693 KAP family P-loop domain 16 381 3.6E-47 T 29-03-2018 IPR011646 KAP family P-loop domain MC49_RS03145 c1a32735101fc7231dcd515acce12ad4 648 Gene3D G3DSA:3.40.50.300 14 254 4.9E-9 T 29-03-2018 MC49_RS01300 266404ea56d25495e0ff8d23f222012c 163 TIGRFAM TIGR03993 hydrog_HybE: [NiFe] hydrogenase assembly chaperone, HybE family 16 155 1.3E-43 T 29-03-2018 IPR023994 [NiFe]-hydrogenase assembly, chaperone, HybE MC49_RS01300 266404ea56d25495e0ff8d23f222012c 163 Pfam PF11939 [NiFe]-hydrogenase assembly, chaperone, HybE 12 156 5.1E-40 T 29-03-2018 IPR023994 [NiFe]-hydrogenase assembly, chaperone, HybE MC49_RS01300 266404ea56d25495e0ff8d23f222012c 163 ProDom PD008308 HUPJ HYDROGENASE EXPRESSION/FORMATION HYDROGENASE-2 HYBE COMPONENT OPERON ELECTRON METAL-BINDING IRON 16 157 4.0E-51 T 29-03-2018 IPR023994 [NiFe]-hydrogenase assembly, chaperone, HybE MC49_RS10630 ad109a958a623f23fa76deb810afba95 236 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 20 232 1.7E-60 T 29-03-2018 IPR006214 Bax inhibitor 1-related MC49_RS18805 afd3ead8f04362267b8148ffb91928da 365 Gene3D G3DSA:1.10.3290.10 21 281 5.0E-50 T 29-03-2018 IPR003812 Fido domain MC49_RS18805 afd3ead8f04362267b8148ffb91928da 365 SUPERFAMILY SSF140931 96 290 2.35E-39 T 29-03-2018 IPR003812 Fido domain MC49_RS18805 afd3ead8f04362267b8148ffb91928da 365 Gene3D G3DSA:1.10.10.10 282 364 1.8E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS18805 afd3ead8f04362267b8148ffb91928da 365 Pfam PF02661 Fic/DOC family 110 221 1.2E-18 T 29-03-2018 IPR003812 Fido domain MC49_RS18805 afd3ead8f04362267b8148ffb91928da 365 Pfam PF13776 Domain of unknown function (DUF4172) 2 81 1.6E-23 T 29-03-2018 IPR025230 Domain of unknown function DUF4172 MC49_RS06785 96a4d9c62850e49095cb568dfa3bb763 262 SMART SM01252 8 106 7.7E-35 T 29-03-2018 IPR018004 KilA, N-terminal/APSES-type HTH, DNA-binding MC49_RS06785 96a4d9c62850e49095cb568dfa3bb763 262 Pfam PF04383 KilA-N domain 9 102 6.9E-21 T 29-03-2018 IPR018004 KilA, N-terminal/APSES-type HTH, DNA-binding MC49_RS04710 6ff0680c831262e3a72760fafa6a1b4e 351 ProSitePatterns PS00875 Bacterial type II secretion system protein D signature. 295 328 - T 29-03-2018 IPR004845 Type II secretion system GspD, conserved site GO:0008565 MC49_RS04710 6ff0680c831262e3a72760fafa6a1b4e 351 Pfam PF00263 Bacterial type II and III secretion system protein 191 349 3.6E-44 T 29-03-2018 IPR004846 Type II/III secretion system GO:0009306 MC49_RS04710 6ff0680c831262e3a72760fafa6a1b4e 351 PRINTS PR00811 Bacterial general secretion pathway protein D signature 314 332 1.4E-10 T 29-03-2018 IPR001775 GspD/PilQ family MC49_RS04710 6ff0680c831262e3a72760fafa6a1b4e 351 PRINTS PR00811 Bacterial general secretion pathway protein D signature 187 211 1.4E-10 T 29-03-2018 IPR001775 GspD/PilQ family MC49_RS04710 6ff0680c831262e3a72760fafa6a1b4e 351 PRINTS PR00811 Bacterial general secretion pathway protein D signature 337 351 1.4E-10 T 29-03-2018 IPR001775 GspD/PilQ family MC49_RS04710 6ff0680c831262e3a72760fafa6a1b4e 351 Pfam PF03958 Bacterial type II/III secretion system short domain 63 127 9.7E-10 T 29-03-2018 IPR005644 NolW-like MC49_RS14025 cd63e0294b50896a3d168287177457ce 324 Gene3D G3DSA:3.40.50.150 76 324 9.6E-23 T 29-03-2018 MC49_RS14025 cd63e0294b50896a3d168287177457ce 324 SUPERFAMILY SSF53335 92 324 7.23E-35 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS14025 cd63e0294b50896a3d168287177457ce 324 Pfam PF08003 Protein of unknown function (DUF1698) 7 323 3.4E-162 T 29-03-2018 IPR027555 tRNA (mo5U34)-methyltransferase-like MC49_RS14025 cd63e0294b50896a3d168287177457ce 324 TIGRFAM TIGR00452 TIGR00452: tRNA (mo5U34)-methyltransferase 13 322 1.2E-144 T 29-03-2018 IPR010017 tRNA U34 carboxymethyltransferase GO:0002098|GO:0016765 MC49_RS14025 cd63e0294b50896a3d168287177457ce 324 Hamap MF_01590 tRNA U34 carboxymethyltransferase [cmoB]. 13 323 53.77 T 29-03-2018 IPR010017 tRNA U34 carboxymethyltransferase GO:0002098|GO:0016765 MC49_RS07620 f00ffc33b5b19173510553855775983c 316 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 287 37.644 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 MC49_RS07620 f00ffc33b5b19173510553855775983c 316 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2 285 1.1E-98 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 MC49_RS07620 f00ffc33b5b19173510553855775983c 316 Pfam PF02401 LytB protein 3 283 1.3E-92 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 MC49_RS07620 f00ffc33b5b19173510553855775983c 316 Gene3D G3DSA:3.40.50.1220 14 290 2.8E-4 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain MC49_RS13980 b31e2439afa99a77ee3c98c7c5938352 185 Pfam PF07273 Protein of unknown function (DUF1439) 27 178 2.2E-45 T 29-03-2018 IPR010835 Protein of unknown function DUF1439 MC49_RS01065 d76bbb156373ad7aa142180932910857 816 Pfam PF03135 CagE, TrbE, VirB family, component of type IV transporter system 187 388 2.2E-13 T 29-03-2018 IPR018145 CagE, TrbE, VirB component of type IV transporter system, central domain GO:0005524 MC49_RS01065 d76bbb156373ad7aa142180932910857 816 SUPERFAMILY SSF52540 398 738 2.41E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MC49_RS01065 d76bbb156373ad7aa142180932910857 816 SMART SM00382 440 704 6.3E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain MC49_RS01065 d76bbb156373ad7aa142180932910857 816 Gene3D G3DSA:3.40.50.300 386 770 1.2E-32 T 29-03-2018 MC49_RS00445 d68dc0f2eb0439dcb3ea2df8f70cb9c3 129 Gene3D G3DSA:1.20.120.10 25 129 1.7E-18 T 29-03-2018 MC49_RS00445 d68dc0f2eb0439dcb3ea2df8f70cb9c3 129 Pfam PF07361 Cytochrome b562 26 129 3.0E-30 T 29-03-2018 IPR009155 Cytochrome b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900|GO:0042597 MC49_RS00445 d68dc0f2eb0439dcb3ea2df8f70cb9c3 129 PIRSF PIRSF000029 1 129 2.0E-42 T 29-03-2018 IPR009155 Cytochrome b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900|GO:0042597 MC49_RS00445 d68dc0f2eb0439dcb3ea2df8f70cb9c3 129 SUPERFAMILY SSF47175 25 129 4.0E-29 T 29-03-2018 IPR010980 Cytochrome c/b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900 MC49_RS08385 39b2526e701ef01baeb2fa7f3a902234 225 Pfam PF02361 Cobalt transport protein 10 221 2.2E-43 T 29-03-2018 IPR003339 ABC/ECF transporter, transmembrane component MC49_RS08385 39b2526e701ef01baeb2fa7f3a902234 225 TIGRFAM TIGR02454 ECF_T_CbiQ: cobalt ECF transporter T component CbiQ 16 216 6.3E-48 T 29-03-2018 IPR012809 Cobalt ECF transporter T component CbiQ GO:0005887|GO:0006824|GO:0043190 MC49_RS16970 680a950726a7b0079da0dd7fb8819004 350 Gene3D G3DSA:2.60.40.1090 216 350 3.9E-22 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS16970 680a950726a7b0079da0dd7fb8819004 350 Pfam PF00419 Fimbrial protein 211 350 4.5E-9 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS16970 680a950726a7b0079da0dd7fb8819004 350 SUPERFAMILY SSF49401 215 350 1.49E-18 T 29-03-2018 IPR008966 Adhesion domain MC49_RS09505 9483779113a2ba3c17733412f211fb6e 219 Pfam PF08242 Methyltransferase domain 54 152 2.0E-9 T 29-03-2018 IPR013217 Methyltransferase type 12 MC49_RS09505 9483779113a2ba3c17733412f211fb6e 219 Gene3D G3DSA:3.40.50.150 25 213 1.3E-11 T 29-03-2018 MC49_RS09505 9483779113a2ba3c17733412f211fb6e 219 SUPERFAMILY SSF53335 20 187 7.32E-16 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS09505 9483779113a2ba3c17733412f211fb6e 219 PIRSF PIRSF011491 1 219 1.9E-83 T 29-03-2018 IPR016584 Methyltransferase VrtF-like MC49_RS16915 be0ee44784ff5fe9cfca2159b5c5e985 132 Pfam PF00589 Phage integrase family 10 121 1.0E-8 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MC49_RS16915 be0ee44784ff5fe9cfca2159b5c5e985 132 Gene3D G3DSA:1.10.443.10 3 131 1.9E-7 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 MC49_RS16915 be0ee44784ff5fe9cfca2159b5c5e985 132 SUPERFAMILY SSF56349 7 130 7.06E-14 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MC49_RS15075 16e6a6bef4ce0b203f05bb18ee21ba73 389 Gene3D G3DSA:1.25.40.10 208 343 9.9E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MC49_RS15075 16e6a6bef4ce0b203f05bb18ee21ba73 389 SUPERFAMILY SSF81901 112 324 2.88E-12 T 29-03-2018 MC49_RS15075 16e6a6bef4ce0b203f05bb18ee21ba73 389 Gene3D G3DSA:1.25.40.10 90 207 2.5E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MC49_RS15075 16e6a6bef4ce0b203f05bb18ee21ba73 389 Gene3D G3DSA:1.25.40.10 19 89 3.2E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 MC49_RS15075 16e6a6bef4ce0b203f05bb18ee21ba73 389 Hamap MF_00994 Lipopolysaccharide assembly protein B [lapB]. 4 387 35.428 T 29-03-2018 IPR030865 Lipopolysaccharide assembly protein B GO:0008653 MC49_RS03220 6f4d41561c8ca44a33118cad8f412fb0 149 Gene3D G3DSA:3.40.50.10110 1 146 1.9E-51 T 29-03-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 MC49_RS03220 6f4d41561c8ca44a33118cad8f412fb0 149 Pfam PF04364 DNA polymerase III chi subunit, HolC 1 141 1.4E-39 T 29-03-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 MC49_RS03220 6f4d41561c8ca44a33118cad8f412fb0 149 SUPERFAMILY SSF102400 1 143 3.14E-47 T 29-03-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 MC49_RS16085 f2372d6aa72c964357a1735fc21c6f1a 138 PIRSF PIRSF016789 5 125 4.8E-44 T 29-03-2018 IPR007401 Protein of unknown function DUF454 MC49_RS16085 f2372d6aa72c964357a1735fc21c6f1a 138 Pfam PF04304 Protein of unknown function (DUF454) 6 120 1.2E-39 T 29-03-2018 IPR007401 Protein of unknown function DUF454 MC49_RS14575 9a7d51cf5a5246bac7022806e486ca93 159 Gene3D G3DSA:2.170.130.10 39 158 2.7E-11 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MC49_RS14575 9a7d51cf5a5246bac7022806e486ca93 159 Pfam PF07715 TonB-dependent Receptor Plug Domain 79 145 5.3E-10 T 29-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 MC49_RS14575 9a7d51cf5a5246bac7022806e486ca93 159 SUPERFAMILY SSF56935 71 154 1.19E-12 T 29-03-2018 MC49_RS06340 b88a893f0f8605bf25607bbabeeea2c3 209 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 5 137 4.1E-7 T 29-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain MC49_RS06340 b88a893f0f8605bf25607bbabeeea2c3 209 Gene3D G3DSA:3.10.50.40 1 186 1.4E-25 T 29-03-2018 MC49_RS06340 b88a893f0f8605bf25607bbabeeea2c3 209 SUPERFAMILY SSF54534 2 140 1.43E-29 T 29-03-2018 MC49_RS01400 741890ee6f1fb8434c7af2412e445dea 584 SUPERFAMILY SSF53822 438 579 1.09E-64 T 29-03-2018 IPR028082 Periplasmic binding protein-like I MC49_RS01400 741890ee6f1fb8434c7af2412e445dea 584 SUPERFAMILY SSF53822 172 200 1.09E-64 T 29-03-2018 IPR028082 Periplasmic binding protein-like I MC49_RS01400 741890ee6f1fb8434c7af2412e445dea 584 SUPERFAMILY SSF53822 270 405 1.09E-64 T 29-03-2018 IPR028082 Periplasmic binding protein-like I MC49_RS01400 741890ee6f1fb8434c7af2412e445dea 584 Pfam PF04348 LppC putative lipoprotein 270 575 3.4E-65 T 29-03-2018 IPR007443 Penicillin-binding protein activator LpoA MC49_RS01400 741890ee6f1fb8434c7af2412e445dea 584 Pfam PF04348 LppC putative lipoprotein 42 224 3.3E-27 T 29-03-2018 IPR007443 Penicillin-binding protein activator LpoA MC49_RS01400 741890ee6f1fb8434c7af2412e445dea 584 Gene3D G3DSA:3.40.50.2300 381 568 3.5E-13 T 29-03-2018 MC49_RS01400 741890ee6f1fb8434c7af2412e445dea 584 Gene3D G3DSA:3.40.50.2300 171 380 9.1E-33 T 29-03-2018 MC49_RS15680 19a9a5433b907c6690d466832622a4de 78 Pfam PF06945 Protein of unknown function (DUF1289) 12 58 1.4E-19 T 29-03-2018 IPR010710 Protein of unknown function DUF1289 MC49_RS07490 f1258b6a8c914107b9958de404ec414c 180 Pfam PF13302 Acetyltransferase (GNAT) domain 7 147 9.7E-23 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MC49_RS07490 f1258b6a8c914107b9958de404ec414c 180 Gene3D G3DSA:3.40.630.30 1 180 1.2E-25 T 29-03-2018 MC49_RS07490 f1258b6a8c914107b9958de404ec414c 180 SUPERFAMILY SSF55729 2 154 3.29E-32 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS12660 61e2da14fc6f87d40362d5f689b9e1c2 110 SUPERFAMILY SSF141488 25 80 2.09E-12 T 29-03-2018 IPR018660 C-type lysozyme inhibitor MC49_RS12660 61e2da14fc6f87d40362d5f689b9e1c2 110 Pfam PF09864 Membrane-bound lysozyme-inhibitor of c-type lysozyme 29 88 1.5E-12 T 29-03-2018 IPR018660 C-type lysozyme inhibitor MC49_RS07700 83da31fa169e2beacd1c597a462a31ab 86 Pfam PF04380 Membrane fusogenic activity 1 78 4.2E-29 T 29-03-2018 IPR007475 Membrane fusogenic activity MC49_RS00215 a81e4129632c16bf3826747175ad0b39 330 Pfam PF04233 Phage Mu protein F like protein 193 298 1.9E-9 T 29-03-2018 IPR006528 Phage head morphogenesis domain MC49_RS01175 8dc4bae85a742664c89db2a284d13f56 285 Pfam PF10134 Replication initiator protein A 32 261 1.1E-91 T 29-03-2018 IPR018777 Replication initiator protein A MC49_RS01175 8dc4bae85a742664c89db2a284d13f56 285 Gene3D G3DSA:1.10.10.10 60 167 1.5E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS03535 d7ed34aeac2619cf20d865ca1628f459 207 Pfam PF04225 Opacity-associated protein A LysM-like domain 126 207 2.6E-20 T 29-03-2018 IPR007340 Opacity-associated protein A MC49_RS11550 4fbd3924aedc51b94c71680d60283603 178 Pfam PF04657 Putative inner membrane exporter, YdcZ 11 149 2.2E-37 T 29-03-2018 IPR006750 Putative inner membrane exporter, YdcZ MC49_RS11575 f28cfba481f2515efcf7cb2d23a75ae5 148 Gene3D G3DSA:3.10.180.10 12 140 1.8E-11 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MC49_RS11575 f28cfba481f2515efcf7cb2d23a75ae5 148 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 19 134 3.3E-4 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MC49_RS11575 f28cfba481f2515efcf7cb2d23a75ae5 148 SUPERFAMILY SSF54593 19 136 5.34E-13 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MC49_RS10310 654f079646f8d15874e54bc80a897ef2 259 Gene3D G3DSA:3.40.50.1820 7 258 1.9E-52 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS10310 654f079646f8d15874e54bc80a897ef2 259 Pfam PF12697 Alpha/beta hydrolase family 23 249 2.5E-24 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 MC49_RS10310 654f079646f8d15874e54bc80a897ef2 259 SUPERFAMILY SSF53474 8 257 1.1E-54 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS01675 540eaf4a4ac44b091a355370b30c415e 373 Pfam PF04085 rod shape-determining protein MreC 125 269 3.4E-37 T 29-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 MC49_RS01675 540eaf4a4ac44b091a355370b30c415e 373 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 1 275 1.4E-108 T 29-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 MC49_RS03105 e0018856eb9fe5c8c9103e6fff37809c 232 SUPERFAMILY SSF46785 1 61 1.6E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS03105 e0018856eb9fe5c8c9103e6fff37809c 232 Pfam PF08279 HTH domain 6 60 1.2E-14 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 MC49_RS03105 e0018856eb9fe5c8c9103e6fff37809c 232 Gene3D G3DSA:1.10.10.10 1 64 1.9E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS03105 e0018856eb9fe5c8c9103e6fff37809c 232 Pfam PF13280 WYL domain 140 221 2.5E-11 T 29-03-2018 IPR026881 WYL domain MC49_RS02605 dd71c7b0ec42a6787483ffda00544dfe 445 Pfam PF02447 GntP family permease 5 441 1.2E-153 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 MC49_RS02605 dd71c7b0ec42a6787483ffda00544dfe 445 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 4 444 1.3E-158 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 MC49_RS02605 dd71c7b0ec42a6787483ffda00544dfe 445 PIRSF PIRSF002746 1 445 1.0E-148 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 MC49_RS09095 9f469bf04e3abbbc0c396fa546f2ad1b 300 Pfam PF04976 DMSO reductase anchor subunit (DmsC) 2 172 3.2E-20 T 29-03-2018 IPR007059 DMSO reductase anchor subunit (DmsC) GO:0016021|GO:0019645 MC49_RS09095 9f469bf04e3abbbc0c396fa546f2ad1b 300 Gene3D G3DSA:1.20.1630.10 2 299 1.5E-30 T 29-03-2018 MC49_RS06175 4fd572b380c94d0c3db42b0df6c311b4 129 Gene3D G3DSA:1.10.287.620 22 129 1.4E-4 T 29-03-2018 MC49_RS06175 4fd572b380c94d0c3db42b0df6c311b4 129 Pfam PF06476 Protein of unknown function (DUF1090) 16 119 2.5E-36 T 29-03-2018 IPR009468 Protein of unknown function DUF1090 MC49_RS09230 33573e523f2c1364f72b5674b7e4d0d5 84 Pfam PF03692 Putative zinc- or iron-chelating domain 3 57 1.9E-5 T 29-03-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein MC49_RS07135 f627117d5fda887fdececb6d45178db8 241 Gene3D G3DSA:3.40.50.880 1 230 5.5E-35 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MC49_RS07135 f627117d5fda887fdececb6d45178db8 241 SUPERFAMILY SSF52317 1 210 5.8E-33 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like MC49_RS07135 f627117d5fda887fdececb6d45178db8 241 Pfam PF03575 Peptidase family S51 3 205 2.0E-41 T 29-03-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 MC49_RS10675 b2ca425e4cfd4c32a9aee1823eed2a02 82 Pfam PF04226 Transglycosylase associated protein 33 81 2.5E-11 T 29-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 MC49_RS13070 805276958bc70c09225fa992d6b76b64 459 Pfam PF13264 Domain of unknown function (DUF4055) 246 384 7.5E-37 T 29-03-2018 IPR025129 Domain of unknown function DUF4055 MC49_RS05765 f4e6ce41bc1a6f5d9aa84c5a85b04ad7 410 Gene3D G3DSA:3.40.50.2000 6 236 1.9E-10 T 29-03-2018 MC49_RS05765 f4e6ce41bc1a6f5d9aa84c5a85b04ad7 410 Pfam PF04007 Protein of unknown function (DUF354) 132 405 1.6E-5 T 29-03-2018 IPR007152 Protein of unknown function DUF354 MC49_RS05765 f4e6ce41bc1a6f5d9aa84c5a85b04ad7 410 SUPERFAMILY SSF53756 123 408 3.71E-21 T 29-03-2018 MC49_RS05765 f4e6ce41bc1a6f5d9aa84c5a85b04ad7 410 SUPERFAMILY SSF53756 10 68 3.71E-21 T 29-03-2018 MC49_RS16855 388a60ec8c3790e3715dae14e01dcf18 181 SUPERFAMILY SSF55729 18 168 3.42E-13 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS16855 388a60ec8c3790e3715dae14e01dcf18 181 Gene3D G3DSA:3.40.630.30 19 181 8.9E-13 T 29-03-2018 MC49_RS18220 8330111bc89d2dc82ea75cc20fa1f0f9 290 Pfam PF07395 Mig-14 38 285 5.5E-29 T 29-03-2018 IPR009977 Mig-14 MC49_RS18220 8330111bc89d2dc82ea75cc20fa1f0f9 290 SUPERFAMILY SSF55729 132 279 3.18E-12 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS18220 8330111bc89d2dc82ea75cc20fa1f0f9 290 Gene3D G3DSA:3.40.630.30 100 284 8.7E-13 T 29-03-2018 MC49_RS05025 1f142c2cfbcff27373421d8ae1c93af8 211 Pfam PF06226 Protein of unknown function (DUF1007) 8 209 2.2E-52 T 29-03-2018 IPR010412 Protein of unknown function DUF1007 MC49_RS05025 1f142c2cfbcff27373421d8ae1c93af8 211 PIRSF PIRSF008159 1 210 1.3E-52 T 29-03-2018 IPR016537 Uncharacterised conserved protein UCP008159, MC49_RS15595 8fe37f7b040d0ead7312e34e679832b9 73 Pfam PF06667 Phage shock protein B 3 72 2.4E-28 T 29-03-2018 IPR009554 Phage shock protein B GO:0006355|GO:0009271 MC49_RS15595 8fe37f7b040d0ead7312e34e679832b9 73 TIGRFAM TIGR02976 phageshock_pspB: phage shock protein B 1 72 1.3E-25 T 29-03-2018 IPR009554 Phage shock protein B GO:0006355|GO:0009271 MC49_RS05315 50bddbe9eaac2beaeb8a15110d6cd555 217 Pfam PF01914 MarC family integral membrane protein 8 207 2.1E-21 T 29-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 MC49_RS07365 51596d4b6539a8c9dde2c57a777058cd 257 SUPERFAMILY SSF74653 154 249 6.02E-17 T 29-03-2018 MC49_RS07365 51596d4b6539a8c9dde2c57a777058cd 257 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 178 257 5.1E-15 T 29-03-2018 IPR006260 TonB, C-terminal GO:0006810 MC49_RS07365 51596d4b6539a8c9dde2c57a777058cd 257 Gene3D G3DSA:3.30.1150.10 61 257 1.2E-18 T 29-03-2018 MC49_RS07365 51596d4b6539a8c9dde2c57a777058cd 257 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 179 256 3.3E-16 T 29-03-2018 IPR006260 TonB, C-terminal GO:0006810 MC49_RS00255 ede3c11f1d7dca2ade467d30127592a7 102 TIGRFAM TIGR01594 holin_lambda: phage holin, lambda family 1 96 2.9E-27 T 29-03-2018 IPR006481 Bacteriophage lambda, GpS, holin MC49_RS00255 ede3c11f1d7dca2ade467d30127592a7 102 Pfam PF05106 Phage holin family (Lysis protein S) 3 94 3.4E-29 T 29-03-2018 IPR006481 Bacteriophage lambda, GpS, holin MC49_RS03675 75b5a81d56c0bd6aa406bf0c5839abd7 332 Gene3D G3DSA:3.40.50.1820 32 332 3.5E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS03675 75b5a81d56c0bd6aa406bf0c5839abd7 332 Pfam PF12146 Serine aminopeptidase, S33 56 315 5.9E-50 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 MC49_RS03675 75b5a81d56c0bd6aa406bf0c5839abd7 332 SUPERFAMILY SSF53474 16 329 3.47E-29 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold MC49_RS13130 0c08be02b6bb927ece349237d15c9593 232 TIGRFAM TIGR01600 phage_tail_L: phage minor tail protein L 13 231 1.7E-73 T 29-03-2018 IPR006487 Bacteriophage lambda, GpL, minor tail MC49_RS13130 0c08be02b6bb927ece349237d15c9593 232 Pfam PF05100 Phage minor tail protein L 30 231 4.8E-76 T 29-03-2018 IPR006487 Bacteriophage lambda, GpL, minor tail MC49_RS11885 050d5a3baebf90b6ba5ee671b47ff2a1 159 Gene3D G3DSA:2.30.110.20 2 159 3.2E-41 T 29-03-2018 IPR008514 Type VI secretion system effector, Hcp MC49_RS11885 050d5a3baebf90b6ba5ee671b47ff2a1 159 TIGRFAM TIGR03344 VI_effect_Hcp1: type VI secretion system effector, Hcp1 family 1 156 1.6E-57 T 29-03-2018 IPR008514 Type VI secretion system effector, Hcp MC49_RS11885 050d5a3baebf90b6ba5ee671b47ff2a1 159 SUPERFAMILY SSF141452 2 157 2.09E-32 T 29-03-2018 IPR008514 Type VI secretion system effector, Hcp MC49_RS11885 050d5a3baebf90b6ba5ee671b47ff2a1 159 Pfam PF05638 Type VI secretion system effector, Hcp 18 143 6.3E-20 T 29-03-2018 IPR008514 Type VI secretion system effector, Hcp MC49_RS06895 467c164feb411859e59383163917480c 975 Pfam PF06791 Prophage tail length tape measure protein 269 401 2.4E-34 T 29-03-2018 IPR009628 Bacteriophage lambda, GpH, tail tape measure, N-terminal MC49_RS06895 467c164feb411859e59383163917480c 975 TIGRFAM TIGR01541 tape_meas_lam_C: phage tail tape measure protein, lambda family 627 939 9.9E-48 T 29-03-2018 IPR006431 Bacteriophage lambda, GpH, tail tape measure, C-terminal MC49_RS06895 467c164feb411859e59383163917480c 975 Pfam PF09718 Lambda phage tail tape-measure protein (Tape_meas_lam_C) 778 848 4.1E-17 T 29-03-2018 IPR006431 Bacteriophage lambda, GpH, tail tape measure, C-terminal MC49_RS02130 c858a057d579dded17c93ce3442081d9 168 Pfam PF04186 FxsA cytoplasmic membrane protein 8 110 9.7E-33 T 29-03-2018 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 MC49_RS08125 362ef23799e3b699c93703ccc7f20479 219 Pfam PF17185 NlpE C-terminal OB domain 131 219 1.1E-33 T 29-03-2018 IPR033450 NlpE, C-terminal OB domain MC49_RS08125 362ef23799e3b699c93703ccc7f20479 219 Pfam PF04170 NlpE N-terminal domain 38 123 1.2E-24 T 29-03-2018 IPR007298 Copper resistance lipoprotein NlpE MC49_RS05810 5d63d5a4af8a8047defe13bedc878227 142 Pfam PF05656 Protein of unknown function (DUF805) 8 132 8.8E-16 T 29-03-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 MC49_RS17660 223214951871883633f1cbba45770bad 504 Pfam PF06381 Protein of unknown function (DUF1073) 84 431 6.1E-91 T 29-03-2018 IPR024459 Protein of unknown function DUF1073 MC49_RS11400 a8bc711b92ae660bcee4a5b490bd216d 310 Pfam PF07670 Nucleoside recognition 19 72 1.2E-5 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 MC49_RS02045 ef091225e96762845ffc121cc829212f 216 ProDom PD037531 MEMBRANE HYDROGENASE SUBUNIT COMPONENT HYDROGENASE-4 E OXIDOREDUCTASE PRECURSOR SIGNAL 1.-.-.- 13 197 4.0E-71 T 29-03-2018 MC49_RS02045 ef091225e96762845ffc121cc829212f 216 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 128 211 1.5E-9 T 29-03-2018 MC49_RS00885 b78289d2b7c2a76ed4756b1468be2f68 111 PRINTS PR01853 Bacterial YajC preprotein translocase signature 60 78 2.9E-17 T 29-03-2018 IPR003849 Preprotein translocase YajC MC49_RS00885 b78289d2b7c2a76ed4756b1468be2f68 111 PRINTS PR01853 Bacterial YajC preprotein translocase signature 22 42 2.9E-17 T 29-03-2018 IPR003849 Preprotein translocase YajC MC49_RS00885 b78289d2b7c2a76ed4756b1468be2f68 111 SMART SM01323 20 103 1.1E-39 T 29-03-2018 IPR003849 Preprotein translocase YajC MC49_RS00885 b78289d2b7c2a76ed4756b1468be2f68 111 Pfam PF02699 Preprotein translocase subunit 23 100 5.1E-28 T 29-03-2018 IPR003849 Preprotein translocase YajC MC49_RS00885 b78289d2b7c2a76ed4756b1468be2f68 111 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 20 103 9.4E-34 T 29-03-2018 IPR003849 Preprotein translocase YajC MC49_RS16040 66967091244413bff7516c938438d2dd 464 Pfam PF00375 Sodium:dicarboxylate symporter family 30 443 1.1E-100 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MC49_RS16040 66967091244413bff7516c938438d2dd 464 SUPERFAMILY SSF118215 30 442 2.09E-95 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MC49_RS16040 66967091244413bff7516c938438d2dd 464 Gene3D G3DSA:1.10.3860.10 19 451 8.3E-94 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MC49_RS16040 66967091244413bff7516c938438d2dd 464 PRINTS PR00173 Glutamate-aspartate symporter signature 398 418 3.2E-27 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MC49_RS16040 66967091244413bff7516c938438d2dd 464 PRINTS PR00173 Glutamate-aspartate symporter signature 183 205 3.2E-27 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MC49_RS16040 66967091244413bff7516c938438d2dd 464 PRINTS PR00173 Glutamate-aspartate symporter signature 76 96 3.2E-27 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MC49_RS16040 66967091244413bff7516c938438d2dd 464 PRINTS PR00173 Glutamate-aspartate symporter signature 106 131 3.2E-27 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MC49_RS16040 66967091244413bff7516c938438d2dd 464 PRINTS PR00173 Glutamate-aspartate symporter signature 28 48 3.2E-27 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MC49_RS16040 66967091244413bff7516c938438d2dd 464 PRINTS PR00173 Glutamate-aspartate symporter signature 371 390 3.2E-27 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MC49_RS10535 aa8fd0da5d141cf85e6ea003f06584dd 46 Pfam PF10766 Multidrug efflux pump-associated protein AcrZ 1 44 7.9E-19 T 29-03-2018 IPR019702 Multidrug efflux pump accessory protein AcrZ GO:0005886|GO:0006855|GO:0015238 MC49_RS10535 aa8fd0da5d141cf85e6ea003f06584dd 46 Hamap MF_01484 Multidrug efflux pump accessory protein AcrZ [acrZ]. 1 46 16.635 T 29-03-2018 IPR019702 Multidrug efflux pump accessory protein AcrZ GO:0005886|GO:0006855|GO:0015238 MC49_RS14565 d0894487b953e7b34da3b031823192c5 153 Pfam PF07308 Protein of unknown function (DUF1456) 3 70 7.2E-27 T 29-03-2018 IPR009921 Domain of unknown function DUF1456 MC49_RS14565 d0894487b953e7b34da3b031823192c5 153 Pfam PF07308 Protein of unknown function (DUF1456) 86 152 4.7E-26 T 29-03-2018 IPR009921 Domain of unknown function DUF1456 MC49_RS00625 b0a91f9fcdc86ba4f98d3f7cac24343b 181 Pfam PF07445 Primosomal replication protein priC 8 176 2.9E-50 T 29-03-2018 IPR010890 Primosomal replication PriB/PriC MC49_RS14830 e5b859c3e71a9ff7ce3efcc335e39382 323 Pfam PF01497 Periplasmic binding protein 55 295 6.5E-22 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 MC49_RS14830 e5b859c3e71a9ff7ce3efcc335e39382 323 Gene3D G3DSA:3.40.50.1980 24 157 7.6E-21 T 29-03-2018 MC49_RS14830 e5b859c3e71a9ff7ce3efcc335e39382 323 SUPERFAMILY SSF53807 52 320 2.16E-39 T 29-03-2018 MC49_RS14830 e5b859c3e71a9ff7ce3efcc335e39382 323 Gene3D G3DSA:3.40.50.1980 158 323 1.2E-28 T 29-03-2018 MC49_RS06855 23058da9b13333629e59e571e5a04416 678 Pfam PF00574 Clp protease 32 191 2.8E-37 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA MC49_RS06855 23058da9b13333629e59e571e5a04416 678 Gene3D G3DSA:3.90.226.10 16 206 3.1E-28 T 29-03-2018 MC49_RS06855 23058da9b13333629e59e571e5a04416 678 PRINTS PR00127 Clp protease catalytic subunit P signature 93 110 7.7E-10 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MC49_RS06855 23058da9b13333629e59e571e5a04416 678 PRINTS PR00127 Clp protease catalytic subunit P signature 169 188 7.7E-10 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MC49_RS06855 23058da9b13333629e59e571e5a04416 678 PRINTS PR00127 Clp protease catalytic subunit P signature 62 82 7.7E-10 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MC49_RS06855 23058da9b13333629e59e571e5a04416 678 SUPERFAMILY SSF52096 30 198 1.62E-48 T 29-03-2018 IPR029045 ClpP/crotonase-like domain MC49_RS07105 2150ad49be23038141e19b4c2758fe3d 224 SUPERFAMILY SSF55718 26 133 2.38E-9 T 29-03-2018 IPR003033 SCP2 sterol-binding domain MC49_RS07105 2150ad49be23038141e19b4c2758fe3d 224 Gene3D G3DSA:3.30.1050.10 28 136 7.0E-8 T 29-03-2018 IPR003033 SCP2 sterol-binding domain MC49_RS07105 2150ad49be23038141e19b4c2758fe3d 224 Pfam PF02036 SCP-2 sterol transfer family 30 128 1.2E-17 T 29-03-2018 IPR003033 SCP2 sterol-binding domain MC49_RS05570 29b7edc4c4a9a55f825018f0130cfeff 416 Pfam PF04932 O-Antigen ligase 195 346 3.4E-9 T 29-03-2018 IPR007016 O-antigen ligase-related MC49_RS04280 5c3686d4d4e7ec2605ca32ddf20c76ba 238 Pfam PF02361 Cobalt transport protein 13 199 7.8E-19 T 29-03-2018 IPR003339 ABC/ECF transporter, transmembrane component MC49_RS12300 3a2f6fc5ebddf62234ebbe111e51334d 215 Pfam PF01810 LysE type translocator 16 211 1.7E-39 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MC49_RS12300 3a2f6fc5ebddf62234ebbe111e51334d 215 PIRSF PIRSF006324 1 215 4.4E-60 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MC49_RS09445 3036a67c8df3128e3c0ab7067ac5f15a 1186 Gene3D G3DSA:2.60.40.10 970 1073 5.5E-7 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS09445 3036a67c8df3128e3c0ab7067ac5f15a 1186 SUPERFAMILY SSF49373 1004 1069 1.75E-6 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS09445 3036a67c8df3128e3c0ab7067ac5f15a 1186 Pfam PF03538 Salmonella virulence plasmid 28.1kDa A protein 98 311 7.3E-32 T 29-03-2018 IPR018003 Insecticidal toxin complex/plasmid virulence protein MC49_RS09445 3036a67c8df3128e3c0ab7067ac5f15a 1186 SUPERFAMILY SSF49373 1098 1173 1.31E-8 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments MC49_RS09445 3036a67c8df3128e3c0ab7067ac5f15a 1186 Gene3D G3DSA:2.60.40.10 1092 1185 1.2E-7 T 29-03-2018 IPR013783 Immunoglobulin-like fold MC49_RS17400 41ecb1eba219e7b3abbae82cae1e393f 202 Gene3D G3DSA:1.20.144.10 11 202 1.1E-6 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MC49_RS17400 41ecb1eba219e7b3abbae82cae1e393f 202 SUPERFAMILY SSF48317 12 200 8.83E-5 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MC49_RS17400 41ecb1eba219e7b3abbae82cae1e393f 202 Pfam PF14378 PAP2 superfamily 62 198 6.4E-12 T 29-03-2018 IPR026841 Inositolphosphotransferase Aur1/Ipt1 MC49_RS06880 2fabb750ae9bdae8a3476e06b732eb07 175 Pfam PF16461 Lambda phage tail tube protein, TTP 5 155 3.6E-65 T 29-03-2018 IPR032494 Lambda phage tail tube protein MC49_RS01035 4610795f0c91b8a9c3f1e8a7064cc427 422 Pfam PF03743 Bacterial conjugation TrbI-like protein 228 408 4.1E-58 T 29-03-2018 IPR005498 Type IV secretion system, VirB10 / TraB / TrbI MC49_RS06660 fdcf47f375e29226e612d0d1ca92d9da 156 Pfam PF04073 Aminoacyl-tRNA editing domain 23 142 1.0E-27 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MC49_RS06660 fdcf47f375e29226e612d0d1ca92d9da 156 Gene3D G3DSA:3.90.960.10 2 155 1.4E-37 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MC49_RS06660 fdcf47f375e29226e612d0d1ca92d9da 156 SUPERFAMILY SSF55826 5 152 4.45E-39 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MC49_RS14535 73349a31d5b4b094a3d5b10ad56859d3 366 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 5 344 3.5E-89 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 MC49_RS14535 73349a31d5b4b094a3d5b10ad56859d3 366 SUPERFAMILY SSF51395 3 364 7.33E-122 T 29-03-2018 MC49_RS14535 73349a31d5b4b094a3d5b10ad56859d3 366 Gene3D G3DSA:3.20.20.70 5 366 1.2E-123 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS10765 9aa5371144433b91d1beff87102da572 260 Gene3D G3DSA:3.40.50.620 41 178 1.4E-19 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS10765 9aa5371144433b91d1beff87102da572 260 Pfam PF02698 DUF218 domain 54 172 1.2E-16 T 29-03-2018 IPR003848 Domain of unknown function DUF218 MC49_RS10765 9aa5371144433b91d1beff87102da572 260 PIRSF PIRSF005011 6 254 5.4E-125 T 29-03-2018 IPR023604 Uncharacterised protein family SanA MC49_RS00660 1b4b5a7060a89df147dc72d0b97c5923 119 Pfam PF10757 Biofilm formation regulator YbaJ 1 114 4.8E-40 T 29-03-2018 IPR019693 Biofilm formation regulator YbaJ MC49_RS02445 3663bc696cb44fdf603674f401ebc524 885 Pfam PF13954 PapC N-terminal domain 36 182 1.0E-36 T 29-03-2018 IPR025885 PapC, N-terminal domain GO:0005515 MC49_RS02445 3663bc696cb44fdf603674f401ebc524 885 SUPERFAMILY SSF141729 34 157 9.29E-29 T 29-03-2018 MC49_RS02445 3663bc696cb44fdf603674f401ebc524 885 ProSitePatterns PS01151 Fimbrial biogenesis outer membrane usher protein signature. 315 325 - T 29-03-2018 IPR018030 Fimbrial membrane usher, conserved site MC49_RS02445 3663bc696cb44fdf603674f401ebc524 885 Pfam PF00577 Outer membrane usher protein 198 749 7.1E-194 T 29-03-2018 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 MC49_RS02445 3663bc696cb44fdf603674f401ebc524 885 Pfam PF13953 PapC C-terminal domain 760 816 3.0E-13 T 29-03-2018 IPR025949 PapC-like, C-terminal domain MC49_RS06900 7533e59bdb2551492d999f7d91f6464f 109 Pfam PF05939 Phage minor tail protein 2 107 7.0E-35 T 29-03-2018 IPR010265 Bacteriophage lambda, GpM, minor tail MC49_RS01345 d7f51e19485e3f827e2eb7767a56e0d7 316 Pfam PF04393 Protein of unknown function (DUF535) 20 297 6.5E-97 T 29-03-2018 IPR007488 Protein of unknown function DUF535 MC49_RS08990 c66cb948f9de1279d1b50e31769947ad 256 PIRSF PIRSF006648 6 253 1.0E-25 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MC49_RS08990 c66cb948f9de1279d1b50e31769947ad 256 PRINTS PR00164 ABC-2 type transport system membrane protein signature 58 80 2.1E-8 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MC49_RS08990 c66cb948f9de1279d1b50e31769947ad 256 PRINTS PR00164 ABC-2 type transport system membrane protein signature 196 215 2.1E-8 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MC49_RS08990 c66cb948f9de1279d1b50e31769947ad 256 PRINTS PR00164 ABC-2 type transport system membrane protein signature 176 195 2.1E-8 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MC49_RS08990 c66cb948f9de1279d1b50e31769947ad 256 PRINTS PR00164 ABC-2 type transport system membrane protein signature 138 162 2.1E-8 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 MC49_RS08990 c66cb948f9de1279d1b50e31769947ad 256 Pfam PF01061 ABC-2 type transporter 9 218 7.3E-39 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 MC49_RS05200 d44e426bbb4a5e029a55c8decb545993 696 SUPERFAMILY SSF53098 264 453 1.78E-10 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MC49_RS05200 d44e426bbb4a5e029a55c8decb545993 696 Pfam PF00665 Integrase core domain 266 405 5.1E-14 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 MC49_RS05200 d44e426bbb4a5e029a55c8decb545993 696 Gene3D G3DSA:3.30.420.10 256 495 1.7E-25 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 MC49_RS01520 b4dbab2bd24c60864ec8c814a3f019ee 84 Pfam PF01722 BolA-like protein 22 74 2.1E-14 T 29-03-2018 IPR002634 BolA protein MC49_RS01520 b4dbab2bd24c60864ec8c814a3f019ee 84 PIRSF PIRSF003113 1 83 5.6E-22 T 29-03-2018 IPR002634 BolA protein MC49_RS01520 b4dbab2bd24c60864ec8c814a3f019ee 84 SUPERFAMILY SSF82657 2 81 6.15E-29 T 29-03-2018 IPR002634 BolA protein MC49_RS01520 b4dbab2bd24c60864ec8c814a3f019ee 84 Gene3D G3DSA:3.30.300.90 1 83 6.2E-24 T 29-03-2018 MC49_RS02570 bbfc08292f4f2dd07b4869bdf28248c2 470 PIRSF PIRSF006060 1 438 3.5E-50 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MC49_RS02570 bbfc08292f4f2dd07b4869bdf28248c2 470 Pfam PF13520 Amino acid permease 3 403 2.9E-46 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MC49_RS09475 a70ec82aa92da13b8df70d70f4508360 932 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 596 677 1.0E-23 T 29-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 MC49_RS02005 663701a50cbfb0956a701365db0c08b2 65 Pfam PF04328 Selenoprotein, putative 5 65 1.7E-29 T 29-03-2018 IPR007423 Selenoprotein, putative MC49_RS08430 035d7a1b17f67dca2c6cff899f36eec4 189 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 13 132 1.4E-36 T 29-03-2018 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.196|MetaCyc: PWY-2201|MetaCyc: PWY-7377 MC49_RS08430 035d7a1b17f67dca2c6cff899f36eec4 189 Gene3D G3DSA:3.40.50.150 1 188 4.5E-24 T 29-03-2018 MC49_RS08430 035d7a1b17f67dca2c6cff899f36eec4 189 SUPERFAMILY SSF53335 11 170 5.47E-24 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS08430 035d7a1b17f67dca2c6cff899f36eec4 189 Pfam PF03602 Conserved hypothetical protein 95 19 93 1.2E-7 T 29-03-2018 MC49_RS09215 58318dd1395301e6f733877b89a36cb0 243 SUPERFAMILY SSF53335 63 181 3.38E-14 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS09215 58318dd1395301e6f733877b89a36cb0 243 Pfam PF08241 Methyltransferase domain 77 125 2.2E-8 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 MC49_RS09215 58318dd1395301e6f733877b89a36cb0 243 Gene3D G3DSA:3.40.50.150 63 209 2.2E-12 T 29-03-2018 MC49_RS09550 984dbbe55d90cd9c9e13a1063c61260a 89 Pfam PF13356 Arm DNA-binding domain 3 85 3.0E-21 T 29-03-2018 IPR025166 Integrase, DNA-binding domain MC49_RS06240 a56614b8bd936161ee9666bd22b8db52 525 Pfam PF03235 Protein of unknown function DUF262 9 215 2.3E-30 T 29-03-2018 IPR004919 Domain of unknown function DUF262 MC49_RS10710 6cd662c79a8590b86fee7e8b7625ec35 153 SUPERFAMILY SSF55729 1 145 2.87E-32 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase MC49_RS10710 6cd662c79a8590b86fee7e8b7625ec35 153 Gene3D G3DSA:3.40.630.30 1 148 6.8E-33 T 29-03-2018 MC49_RS10710 6cd662c79a8590b86fee7e8b7625ec35 153 Pfam PF00583 Acetyltransferase (GNAT) family 20 142 1.0E-18 T 29-03-2018 IPR000182 GNAT domain GO:0008080 MC49_RS14220 fc44446ec5895996a9957cd364a29a7d 196 PIRSF PIRSF004982 6 190 5.1E-47 T 29-03-2018 IPR004658 Outer membrane lipoprotein Slp GO:0019867 MC49_RS14220 fc44446ec5895996a9957cd364a29a7d 196 TIGRFAM TIGR00752 slp: outer membrane lipoprotein, Slp family 15 185 1.9E-52 T 29-03-2018 IPR004658 Outer membrane lipoprotein Slp GO:0019867 MC49_RS14220 fc44446ec5895996a9957cd364a29a7d 196 Pfam PF03843 Outer membrane lipoprotein Slp family 20 172 3.2E-48 T 29-03-2018 IPR004658 Outer membrane lipoprotein Slp GO:0019867 MC49_RS13270 99547388fdf756a5625f31a5d3e1392a 61 Pfam PF16080 Bacteriophage holin family HP1 5 57 1.7E-26 T 29-03-2018 IPR032118 Bacteriophage holin HP1 family MC49_RS03910 84669b29c76a82b4133013600d499fbd 32 Pfam PF08046 IlvGEDA operon leader peptide 1 28 4.9E-17 T 29-03-2018 IPR012567 IlvGEDA operon leader peptide GO:0009082 MC49_RS19095 a056fbe986afd38ab111007ef443dafe 259 Pfam PF03609 PTS system sorbose-specific iic component 5 236 7.8E-72 T 29-03-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 MC49_RS13080 8c17685c720043d2d57bb00dd18ab4c4 228 Gene3D G3DSA:3.40.50.300 7 228 0.0011 T 29-03-2018 MC49_RS11450 5049c3a3d95792654642911f64ef279b 185 SUPERFAMILY SSF49401 39 184 1.34E-33 T 29-03-2018 IPR008966 Adhesion domain MC49_RS11450 5049c3a3d95792654642911f64ef279b 185 Gene3D G3DSA:2.60.40.1090 37 185 8.8E-32 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS03750 22458d92a042c5bf61b59447ac212bf8 457 Pfam PF04375 HemX, putative uroporphyrinogen-III C-methyltransferase 90 423 9.8E-113 T 29-03-2018 IPR007470 Putative uroporphyrinogen-III C-methyltransferase HemX MC49_RS03750 22458d92a042c5bf61b59447ac212bf8 457 Gene3D G3DSA:1.20.1000.10 21 186 9.7E-5 T 29-03-2018 MC49_RS13975 1e5ed317c6bc15d33240e7b87cb7b689 437 Pfam PF03600 Citrate transporter 15 384 1.7E-42 T 29-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 MC49_RS13975 1e5ed317c6bc15d33240e7b87cb7b689 437 TIGRFAM TIGR00784 citMHS: citrate transporter 1 426 1.5E-83 T 29-03-2018 IPR014738 Citrate transporter GO:0015137|GO:0015746 MC49_RS18415 4f9fba4499dd88c63ada77740eb7ab89 135 ProDom PD083358 MEMBRANE YGFX INNER SIMILAR ECS3768 Y3281 ESCHERICHIA TRANSMEMBRANE YPO0896A STY3202 21 133 2.0E-24 T 29-03-2018 IPR009883 Inner membrane protein YgfX MC49_RS18415 4f9fba4499dd88c63ada77740eb7ab89 135 Pfam PF07254 Membrane-bound toxin component of toxin-antitoxin system 2 130 5.3E-48 T 29-03-2018 IPR009883 Inner membrane protein YgfX MC49_RS08395 0a4f3117b1288421223e3782287a38c1 244 Hamap MF_01462 Cobalt transport protein CbiM [cbiM]. 29 241 27.348 T 29-03-2018 IPR018024 Cobalamin (vitamin B12) biosynthesis protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 MC49_RS08395 0a4f3117b1288421223e3782287a38c1 244 TIGRFAM TIGR00123 cbiM: cobalamin biosynthesis protein CbiM 29 236 1.1E-100 T 29-03-2018 IPR018024 Cobalamin (vitamin B12) biosynthesis protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 MC49_RS08395 0a4f3117b1288421223e3782287a38c1 244 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 30 234 3.0E-50 T 29-03-2018 IPR002751 Cobalamin (vitamin B12) biosynthesis CbiM family GO:0000041|GO:0016021 MC49_RS12770 840abdf67327374b1b4aa09b3a083d1a 254 SUPERFAMILY SSF161098 14 234 2.09E-41 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS12770 840abdf67327374b1b4aa09b3a083d1a 254 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 61 249 5.2E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS12770 840abdf67327374b1b4aa09b3a083d1a 254 Gene3D G3DSA:1.10.3720.10 2 254 9.0E-43 T 29-03-2018 MC49_RS06505 c20f0980b625c6b0b8caca34852809f4 297 Gene3D G3DSA:1.10.3720.10 28 295 1.1E-32 T 29-03-2018 MC49_RS06505 c20f0980b625c6b0b8caca34852809f4 297 SUPERFAMILY SSF161098 28 293 6.28E-43 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS10125 9800be21edbe94a30a88c3b4551b8417 175 Pfam PF08349 Protein of unknown function (DUF1722) 45 162 1.9E-34 T 29-03-2018 IPR013560 Domain of unknown function DUF1722 MC49_RS10815 307786ca8b1a9b272f6a1c327bf17427 620 Pfam PF05170 AsmA family 6 176 5.0E-19 T 29-03-2018 IPR007844 AsmA MC49_RS10815 307786ca8b1a9b272f6a1c327bf17427 620 Pfam PF05170 AsmA family 259 514 1.3E-21 T 29-03-2018 IPR007844 AsmA MC49_RS15255 6dc1c7ddc10c8f585c873ee95347424e 110 Gene3D G3DSA:3.10.450.140 10 109 9.6E-33 T 29-03-2018 IPR007376 dsDNA mimic, putative MC49_RS15255 6dc1c7ddc10c8f585c873ee95347424e 110 ProDom PD020447 UPF0263 YCIU HD0986 VV1228 UNCHARACTERIZED 3D-STRUCTURE VV13059 BCR PM0536 VC1208 8 110 1.0E-22 T 29-03-2018 IPR007376 dsDNA mimic, putative MC49_RS15255 6dc1c7ddc10c8f585c873ee95347424e 110 SUPERFAMILY SSF102816 5 108 1.83E-31 T 29-03-2018 IPR007376 dsDNA mimic, putative MC49_RS15255 6dc1c7ddc10c8f585c873ee95347424e 110 Pfam PF04269 Protein of unknown function, DUF440 8 109 2.4E-31 T 29-03-2018 IPR007376 dsDNA mimic, putative MC49_RS15255 6dc1c7ddc10c8f585c873ee95347424e 110 PIRSF PIRSF004916 1 110 1.9E-34 T 29-03-2018 IPR007376 dsDNA mimic, putative MC49_RS16425 d863a47551703a192bef21803303f4d7 179 Pfam PF07437 YfaZ precursor 1 179 9.1E-52 T 29-03-2018 IPR009998 YfaZ MC49_RS16425 d863a47551703a192bef21803303f4d7 179 Gene3D G3DSA:2.40.160.40 1 179 2.1E-6 T 29-03-2018 MC49_RS05210 7cefe13d504c938790eb0ffd3c699f55 506 Pfam PF15978 Tn7-like transposition protein D 330 447 4.4E-16 T 29-03-2018 IPR032750 Transposon Tn7 transposition protein TnsD, C-termianl MC49_RS05210 7cefe13d504c938790eb0ffd3c699f55 506 Pfam PF06527 TniQ 4 156 1.3E-20 T 29-03-2018 IPR009492 TniQ MC49_RS17755 f2d4e2c93b872b3f25f2773234131be2 77 SUPERFAMILY SSF46575 13 73 1.24E-7 T 29-03-2018 MC49_RS17755 f2d4e2c93b872b3f25f2773234131be2 77 Gene3D G3DSA:1.20.58.250 14 77 8.5E-18 T 29-03-2018 IPR009052 DNA polymerase III-theta, bacterial GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MC49_RS01135 2829a1bdd1187a961d700c7c80494faa 427 SUPERFAMILY SSF52151 10 190 4.97E-35 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MC49_RS01135 2829a1bdd1187a961d700c7c80494faa 427 SUPERFAMILY SSF52151 221 288 4.97E-35 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 MC49_RS01135 2829a1bdd1187a961d700c7c80494faa 427 Gene3D G3DSA:3.40.1090.10 2 411 3.7E-35 T 29-03-2018 MC49_RS01135 2829a1bdd1187a961d700c7c80494faa 427 Pfam PF01734 Patatin-like phospholipase 15 250 4.7E-23 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 MC49_RS17910 8a640c5b14cede22725bb0a933d80285 184 PIRSF PIRSF017018 1 184 3.5E-72 T 29-03-2018 IPR018470 Periplasmic metal-binding protein Tp34-type MC49_RS17910 8a640c5b14cede22725bb0a933d80285 184 Pfam PF10634 Fe2+ transport protein 21 177 2.6E-65 T 29-03-2018 IPR018470 Periplasmic metal-binding protein Tp34-type MC49_RS07540 90de2d1b0cc1ff4320dfc97ccd41899f 263 Pfam PF03883 Peroxide stress protein YaaA 1 243 1.9E-92 T 29-03-2018 IPR005583 Peroxide stress protein YaaA MC49_RS07540 90de2d1b0cc1ff4320dfc97ccd41899f 263 Hamap MF_00652 UPF0246 protein YaaA [yaaA]. 1 255 38.356 T 29-03-2018 IPR005583 Peroxide stress protein YaaA MC49_RS12825 15f757121ddf9c87ebd932f6a54e7511 241 Gene3D G3DSA:3.40.50.150 4 238 1.0E-48 T 29-03-2018 MC49_RS12825 15f757121ddf9c87ebd932f6a54e7511 241 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 14 240 38.337 T 29-03-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 MC49_RS12825 15f757121ddf9c87ebd932f6a54e7511 241 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 16 234 1.2E-89 T 29-03-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 MC49_RS12825 15f757121ddf9c87ebd932f6a54e7511 241 Pfam PF13489 Methyltransferase domain 57 207 2.6E-26 T 29-03-2018 MC49_RS12825 15f757121ddf9c87ebd932f6a54e7511 241 SUPERFAMILY SSF53335 18 227 4.59E-47 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS05245 9c68f85aa502f1ff895adb9f12d14bef 380 Pfam PF13289 SIR2-like domain 172 327 3.1E-13 T 29-03-2018 MC49_RS09740 dc880f44a4656c5895d3e1e036f81871 75 Pfam PF04400 (Na+)-NQR maturation NqrM 23 65 2.1E-22 T 29-03-2018 IPR007495 (Na+)-NQR maturation factor NqrM MC49_RS17895 841da92bff11dd8b4227564978f87fe0 299 Pfam PF09375 Imelysin 53 282 1.5E-18 T 29-03-2018 IPR018976 Peptidase M75, Imelysin MC49_RS18280 e2f83c402c119339f2bc605db7312542 262 TIGRFAM TIGR01581 Mo_ABC_porter: NifC-like ABC-type porter 26 248 9.2E-71 T 29-03-2018 IPR006469 NifC-like ABC-type porter GO:0005215|GO:0006810|GO:0016020 MC49_RS18280 e2f83c402c119339f2bc605db7312542 262 Gene3D G3DSA:1.10.3720.10 3 260 1.7E-36 T 29-03-2018 MC49_RS18280 e2f83c402c119339f2bc605db7312542 262 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 66 249 2.5E-10 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS18280 e2f83c402c119339f2bc605db7312542 262 SUPERFAMILY SSF161098 7 254 1.4E-46 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS17570 5100a936a7f748ea4c706cb262efa149 114 Gene3D G3DSA:3.10.450.40 4 110 2.0E-4 T 29-03-2018 MC49_RS13505 58fab329a7d738abc69fd5d66bf7144b 108 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 9 102 8.4E-14 T 29-03-2018 IPR008407 Branched-chain amino acid transport, AzlD MC49_RS03205 2104dd310790d11f41c97d54bdd33284 360 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 6 358 7.7E-136 T 29-03-2018 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 MC49_RS03205 2104dd310790d11f41c97d54bdd33284 360 Pfam PF03739 Predicted permease YjgP/YjgQ family 9 357 3.8E-73 T 29-03-2018 IPR005495 Permease LptG/LptF-related GO:0016021 MC49_RS17565 a656b6360408dfd31a6856d4301dffac 395 Pfam PF04865 Baseplate J-like protein 78 199 6.9E-11 T 29-03-2018 IPR006949 Baseplate protein J-like MC49_RS15905 81ee41b6830a7c2989bdb197243dc3b2 565 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 21 251 4.4E-29 T 29-03-2018 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 MC49_RS15905 81ee41b6830a7c2989bdb197243dc3b2 565 Hamap MF_01165 Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase [arnT]. 15 564 37.432 T 29-03-2018 IPR022839 Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase GO:0016763 MC49_RS17460 582ca822547d80fdd153c47b18d03818 241 Pfam PF09611 CRISPR-associated protein (Cas_Csy1) 196 230 1.1E-10 T 29-03-2018 IPR013397 CRISPR-associated protein Csy1 MC49_RS17460 582ca822547d80fdd153c47b18d03818 241 Pfam PF09611 CRISPR-associated protein (Cas_Csy1) 22 187 4.0E-39 T 29-03-2018 IPR013397 CRISPR-associated protein Csy1 MC49_RS01535 fe59b65751f482c7a83c92105381b8b2 172 TIGRFAM TIGR04430 OM_asym_MlaD: outer membrane lipid asymmetry maintenance protein MlaD 2 155 5.4E-54 T 29-03-2018 IPR030970 Probable phospholipid ABC transporter-binding protein MlaD GO:0015914 MC49_RS01535 fe59b65751f482c7a83c92105381b8b2 172 Pfam PF02470 MlaD protein 39 116 6.9E-19 T 29-03-2018 IPR003399 Mce/MlaD MC49_RS01130 aade62aaaaf2b44a47b81539a02244b0 205 Pfam PF11769 Protein of unknown function (DUF3313) 20 195 2.0E-22 T 29-03-2018 IPR021747 Protein of unknown function DUF3313 MC49_RS02295 72bd06db2d92ea2b24081646a483dd2d 81 ProDom PD059807 YMJA ECS1872 1 81 2.0E-26 T 29-03-2018 IPR020251 Uncharacterised protein family, YmjA MC49_RS02295 72bd06db2d92ea2b24081646a483dd2d 81 Pfam PF10820 Protein of unknown function (DUF2543) 1 81 2.1E-47 T 29-03-2018 IPR020251 Uncharacterised protein family, YmjA MC49_RS15485 495456de11acfc2724e45695be720bd4 176 Pfam PF02600 Disulfide bond formation protein DsbB 12 160 1.0E-44 T 29-03-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 MC49_RS15485 495456de11acfc2724e45695be720bd4 176 Gene3D G3DSA:1.20.1550.10 1 176 1.6E-52 T 29-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain MC49_RS15485 495456de11acfc2724e45695be720bd4 176 SUPERFAMILY SSF158442 15 162 4.58E-44 T 29-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain MC49_RS15485 495456de11acfc2724e45695be720bd4 176 Hamap MF_00286 Disulfide bond formation protein B [dsbB]. 7 168 22.614 T 29-03-2018 IPR022920 Disulphide bond formation protein DsbB MC49_RS06875 4ee5078ef70dac7cb92b1faa2923a823 132 Pfam PF06141 Phage minor tail protein U 3 130 1.1E-44 T 29-03-2018 IPR009312 Minor tail protein U-like MC49_RS06875 4ee5078ef70dac7cb92b1faa2923a823 132 SUPERFAMILY SSF143749 3 130 1.31E-47 T 29-03-2018 IPR009312 Minor tail protein U-like MC49_RS10850 f24a931158eb7b03847403f8d045cbb5 65 ProDom PD034160 PRECURSOR SIGNAL YFJT INTERGENIC-REGION C0283 YKFB 20 64 0.004 T 29-03-2018 MC49_RS12475 1c38b3b1b3fca52f0f010e45a573a1a9 107 Pfam PF17274 Family of unknown function (DUF5339) 34 106 6.2E-24 T 29-03-2018 IPR020493 Uncharacterised protein family HI0310 MC49_RS12475 1c38b3b1b3fca52f0f010e45a573a1a9 107 Gene3D G3DSA:3.40.190.10 1 105 5.2E-5 T 29-03-2018 MC49_RS08200 74fca3dbdada4784d8b8fb7906178949 453 Pfam PF00324 Amino acid permease 16 452 6.4E-107 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 MC49_RS08200 74fca3dbdada4784d8b8fb7906178949 453 ProSitePatterns PS00218 Amino acid permeases signature. 41 71 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 MC49_RS08200 74fca3dbdada4784d8b8fb7906178949 453 PIRSF PIRSF006060 1 453 9.2E-77 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MC49_RS18295 a52957465408eb4e9bed381a54860444 244 Pfam PF16806 Antiactivator protein ExsD 27 243 1.6E-8 T 29-03-2018 IPR031835 Antiactivator protein ExsD MC49_RS03210 b5b64cfb034234d678e705fa86c3325f 367 Pfam PF03739 Predicted permease YjgP/YjgQ family 5 345 1.5E-73 T 29-03-2018 IPR005495 Permease LptG/LptF-related GO:0016021 MC49_RS03210 b5b64cfb034234d678e705fa86c3325f 367 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 2 348 6.7E-113 T 29-03-2018 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 MC49_RS18355 e7ea803f18a88993e5e64bcf3a7c14cc 442 PIRSF PIRSF006060 1 441 1.6E-51 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MC49_RS18355 e7ea803f18a88993e5e64bcf3a7c14cc 442 TIGRFAM TIGR04299 antiport_PotE: putrescine-ornithine antiporter 4 432 4.4E-240 T 29-03-2018 IPR027566 Putrescine transporter PotE GO:0015496|GO:0015822|GO:0015847 MC49_RS18355 e7ea803f18a88993e5e64bcf3a7c14cc 442 Pfam PF13520 Amino acid permease 9 403 6.1E-50 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MC49_RS18355 e7ea803f18a88993e5e64bcf3a7c14cc 442 Hamap MF_02073 Putrescine transporter PotE [potE]. 8 435 36.161 T 29-03-2018 IPR027566 Putrescine transporter PotE GO:0015496|GO:0015822|GO:0015847 MC49_RS18355 e7ea803f18a88993e5e64bcf3a7c14cc 442 TIGRFAM TIGR00905 2A0302: transporter, basic amino acid/polyamine antiporter (APA) family 1 434 1.4E-141 T 29-03-2018 IPR004754 Amino acid antiporter GO:0006865|GO:0016021 MC49_RS15910 f35faae69adf8fa6681b9c05d06e1fd9 130 SUPERFAMILY SSF103481 36 125 6.28E-12 T 29-03-2018 MC49_RS15910 f35faae69adf8fa6681b9c05d06e1fd9 130 Hamap MF_00538 Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF [arnF]. 2 128 21.825 T 29-03-2018 IPR022832 Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF MC49_RS15920 1bbe7162a84155986c57a637b1c92c9c 553 Hamap MF_01165 Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase [arnT]. 5 552 40.509 T 29-03-2018 IPR022839 Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase GO:0016763 MC49_RS15920 1bbe7162a84155986c57a637b1c92c9c 553 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 10 241 1.7E-31 T 29-03-2018 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 MC49_RS14510 5bdb12d626d6efb822785a244591d482 330 Pfam PF04143 Sulphur transport 18 318 4.2E-88 T 29-03-2018 IPR007272 Sulphur transport domain MC49_RS05215 557e414c1d01010a1d5ea26d4c4d62b1 534 PIRSF PIRSF004567 1 534 2.4E-190 T 29-03-2018 IPR016421 Transposition, TnsE MC49_RS17455 833a1f71827a4490a3c79c993450c1ed 273 Pfam PF09614 CRISPR-associated protein (Cas_Csy2) 6 267 2.9E-60 T 29-03-2018 IPR013398 CRISPR-associated protein Csy2 MC49_RS17735 59f62060af032989241eb15ed2453fe6 164 Gene3D G3DSA:2.130.10.10 21 163 1.6E-4 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 MC49_RS12405 836ef15520796d43f69a9b250991a38a 65 Pfam PF10781 Dextransucrase DSRB 2 62 5.8E-36 T 29-03-2018 IPR019717 Dextransucrase DSRB MC49_RS14260 7862f16698ff466b5c33ed9c8228b6b7 218 SUPERFAMILY SSF56529 11 210 9.81E-66 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 MC49_RS14260 7862f16698ff466b5c33ed9c8228b6b7 218 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 18 208 1.7E-51 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 MC49_RS14260 7862f16698ff466b5c33ed9c8228b6b7 218 Gene3D G3DSA:3.90.850.10 10 215 3.0E-68 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 MC49_RS18270 13098597ddea81720ea223d4d09f5ea1 345 Pfam PF04519 Polymer-forming cytoskeletal 176 272 5.1E-20 T 29-03-2018 IPR007607 Protein of unknown function DUF583 MC49_RS18270 13098597ddea81720ea223d4d09f5ea1 345 Gene3D G3DSA:1.20.1250.20 37 152 9.1E-4 T 29-03-2018 MC49_RS16465 a4a93bbf45a3fb2c5dde5830184cf838 399 SUPERFAMILY SSF58100 45 394 3.66E-38 T 29-03-2018 MC49_RS16465 a4a93bbf45a3fb2c5dde5830184cf838 399 Gene3D G3DSA:1.20.1170.10 77 396 9.2E-12 T 29-03-2018 MC49_RS12615 588b4789d8b1f999e1747f28f170ef05 455 Pfam PF02120 Flagellar hook-length control protein FliK 324 404 2.9E-19 T 29-03-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal MC49_RS04625 1d2589eefebf3ba3c390806d04e747ec 103 Pfam PF04341 Protein of unknown function, DUF485 11 98 1.5E-35 T 29-03-2018 IPR007436 Protein of unknown function DUF485 MC49_RS06530 91ea4074e6f734df10faac942f2ff108 247 Pfam PF04493 Endonuclease V 15 207 3.8E-70 T 29-03-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 MC49_RS06530 91ea4074e6f734df10faac942f2ff108 247 Hamap MF_00801 Endonuclease V [nfi]. 5 217 33.254 T 29-03-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 MC49_RS09610 8f9e2886eb38685f12a5e20ef12aa2b3 182 Pfam PF02325 YGGT family 10 78 1.9E-19 T 29-03-2018 IPR003425 CCB3/YggT GO:0016020 MC49_RS09610 8f9e2886eb38685f12a5e20ef12aa2b3 182 Pfam PF02325 YGGT family 110 170 2.1E-18 T 29-03-2018 IPR003425 CCB3/YggT GO:0016020 MC49_RS10450 0aff367346355ce081925946c97323ac 361 SUPERFAMILY SSF74653 273 361 3.92E-18 T 29-03-2018 MC49_RS10450 0aff367346355ce081925946c97323ac 361 Gene3D G3DSA:3.30.1150.10 283 355 2.6E-16 T 29-03-2018 MC49_RS10450 0aff367346355ce081925946c97323ac 361 Pfam PF06519 TolA C-terminal 269 358 5.5E-28 T 29-03-2018 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0006810|GO:0016020 MC49_RS10450 0aff367346355ce081925946c97323ac 361 TIGRFAM TIGR02794 tolA_full: protein TolA 13 360 4.5E-73 T 29-03-2018 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0006810|GO:0016020 MC49_RS12785 f8612777908b3a3e9a812019d4ecb8e6 308 Pfam PF01148 Cytidylyltransferase family 42 306 1.1E-64 T 29-03-2018 MC49_RS08150 3953623e2ec44739e1e70fd756d57d99 217 SUPERFAMILY SSF161098 9 201 2.09E-47 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS08150 3953623e2ec44739e1e70fd756d57d99 217 Gene3D G3DSA:1.10.3720.10 2 217 2.6E-38 T 29-03-2018 MC49_RS08150 3953623e2ec44739e1e70fd756d57d99 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 214 1.2E-19 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 MC49_RS11635 8189c3284856e51a5512e1d7c2a09705 270 Pfam PF09916 Uncharacterized protein conserved in bacteria (DUF2145) 51 244 1.6E-60 T 29-03-2018 IPR014547 Uncharacterised conserved protein UCP028477 MC49_RS17690 cd13138c6e026d9a2e5c476663f8211e 149 Pfam PF03245 Bacteriophage Rz lysis protein 34 148 6.2E-22 T 29-03-2018 IPR004929 Spanin, inner membrane subunit GO:0019076|GO:0019835 MC49_RS13475 78039eaf6fa83417932751deafe29fd1 297 SUPERFAMILY SSF103481 49 141 3.27E-7 T 29-03-2018 MC49_RS13475 78039eaf6fa83417932751deafe29fd1 297 Pfam PF00892 EamA-like transporter family 163 289 1.7E-8 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MC49_RS13475 78039eaf6fa83417932751deafe29fd1 297 Pfam PF00892 EamA-like transporter family 10 137 7.5E-10 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MC49_RS13475 78039eaf6fa83417932751deafe29fd1 297 SUPERFAMILY SSF103481 191 295 2.22E-8 T 29-03-2018 MC49_RS07355 5c304df615aaffe86cd1e9d8a66d3a8e 320 Pfam PF04773 FecR protein 111 200 2.8E-17 T 29-03-2018 IPR006860 FecR protein MC49_RS07355 5c304df615aaffe86cd1e9d8a66d3a8e 320 PIRSF PIRSF018266 1 317 3.6E-68 T 29-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component MC49_RS07355 5c304df615aaffe86cd1e9d8a66d3a8e 320 Pfam PF16220 Domain of unknown function (DUF4880) 12 53 3.4E-11 T 29-03-2018 IPR032623 FecR, N-terminal MC49_RS13730 322cc52660969b99230cea700bc5777b 483 Pfam PF13163 Protein of unknown function (DUF3999) 41 474 4.2E-115 T 29-03-2018 IPR025060 Protein of unknown function DUF3999 MC49_RS00440 91713a7ef515e555c13a2d42d0738cee 177 Pfam PF01292 Prokaryotic cytochrome b561 6 173 8.0E-23 T 29-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 MC49_RS00440 91713a7ef515e555c13a2d42d0738cee 177 Gene3D G3DSA:1.20.950.20 1 177 8.9E-26 T 29-03-2018 MC49_RS00440 91713a7ef515e555c13a2d42d0738cee 177 SUPERFAMILY SSF81342 4 173 1.8E-23 T 29-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 MC49_RS01655 aa8417fa070610c241288acd43c892ff 1259 Pfam PF13502 AsmA-like C-terminal region 1005 1246 2.1E-49 T 29-03-2018 IPR032712 AsmA-like, C-terminal MC49_RS01655 aa8417fa070610c241288acd43c892ff 1259 Pfam PF13116 Protein of unknown function 501 780 1.6E-89 T 29-03-2018 IPR025263 Domain of unknown function DUF3971 MC49_RS01655 aa8417fa070610c241288acd43c892ff 1259 TIGRFAM TIGR02099 TIGR02099: TIGR02099 family protein 2 1256 0.0 T 29-03-2018 IPR011836 Conserved hypothetical protein CHP02099 MC49_RS17925 95da2e29a107571ca93f19b1591ba41d 172 Pfam PF10688 Bacterial inner membrane protein 7 162 5.8E-51 T 29-03-2018 IPR019629 Uncharacterised protein family HI1736/YgjV MC49_RS17925 95da2e29a107571ca93f19b1591ba41d 172 PIRSF PIRSF011443 3 172 6.2E-49 T 29-03-2018 IPR026267 Inner membrane protein YgjV MC49_RS17390 69699048fc2d3e22f723fb9ea266f558 306 Pfam PF00487 Fatty acid desaturase 30 267 5.0E-23 T 29-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 MC49_RS08140 b55c7237cfb7d139a31f3abae07f0da1 104 Pfam PF16358 RcsF lipoprotein 5 101 2.0E-41 T 29-03-2018 IPR030852 Outer membrane lipoprotein RcsF GO:0009279|GO:0035556 MC49_RS13330 6ab0ab33516ceb9d6e2b220df00776e6 170 PRINTS PR01489 Gram-negative bacterial RTX toxin-activating protein C signature 129 150 3.1E-41 T 29-03-2018 IPR003996 RTX toxin-activating protein C, bacteria GO:0005737|GO:0009404|GO:0016746 MC49_RS13330 6ab0ab33516ceb9d6e2b220df00776e6 170 PRINTS PR01489 Gram-negative bacterial RTX toxin-activating protein C signature 11 27 3.1E-41 T 29-03-2018 IPR003996 RTX toxin-activating protein C, bacteria GO:0005737|GO:0009404|GO:0016746 MC49_RS13330 6ab0ab33516ceb9d6e2b220df00776e6 170 PRINTS PR01489 Gram-negative bacterial RTX toxin-activating protein C signature 53 71 3.1E-41 T 29-03-2018 IPR003996 RTX toxin-activating protein C, bacteria GO:0005737|GO:0009404|GO:0016746 MC49_RS13330 6ab0ab33516ceb9d6e2b220df00776e6 170 PRINTS PR01489 Gram-negative bacterial RTX toxin-activating protein C signature 75 97 3.1E-41 T 29-03-2018 IPR003996 RTX toxin-activating protein C, bacteria GO:0005737|GO:0009404|GO:0016746 MC49_RS13330 6ab0ab33516ceb9d6e2b220df00776e6 170 Pfam PF02794 RTX toxin acyltransferase family 9 128 1.7E-42 T 29-03-2018 IPR003996 RTX toxin-activating protein C, bacteria GO:0005737|GO:0009404|GO:0016746 MC49_RS03100 f25cb096f942b820334d94943202c6ff 156 Gene3D G3DSA:3.40.960.10 20 153 2.8E-24 T 29-03-2018 MC49_RS03100 f25cb096f942b820334d94943202c6ff 156 SUPERFAMILY SSF52980 1 148 1.39E-48 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MC49_RS03100 f25cb096f942b820334d94943202c6ff 156 Pfam PF03852 DNA mismatch endonuclease Vsr 1 74 2.4E-31 T 29-03-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 MC49_RS03100 f25cb096f942b820334d94943202c6ff 156 PIRSF PIRSF018267 1 140 4.1E-48 T 29-03-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 MC49_RS03100 f25cb096f942b820334d94943202c6ff 156 TIGRFAM TIGR00632 vsr: DNA mismatch endonuclease Vsr 1 117 2.9E-41 T 29-03-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 MC49_RS13685 5bb683dd04afff27ae73cb89b1db9379 112 Pfam PF10709 Protein of unknown function (DUF2511) 23 109 1.3E-30 T 29-03-2018 IPR019648 Protein of unknown function DUF2511 MC49_RS16665 3d203f11c1ff17a06154d2d77d975aed 89 ProDom PD063639 YJBD CYTOPLASMIC STY4411 YPO2363 ECS5006 Y1969 1 89 9.0E-9 T 29-03-2018 IPR020317 Uncharacterised protein family YjbD MC49_RS16665 3d203f11c1ff17a06154d2d77d975aed 89 Pfam PF11656 YjbD family (DUF3811) 1 89 2.6E-36 T 29-03-2018 IPR020317 Uncharacterised protein family YjbD MC49_RS07875 3693ccef843aa2011e3291aa94e70307 148 Pfam PF10713 Protein of unknown function (DUF2509) 6 135 1.2E-34 T 29-03-2018 IPR019652 Protein of unknown function DUF2509 MC49_RS14365 b5ecceaa75eb59d7405909b168bd1ad9 463 Pfam PF13520 Amino acid permease 5 435 1.5E-65 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MC49_RS14365 b5ecceaa75eb59d7405909b168bd1ad9 463 PIRSF PIRSF006060 1 463 9.0E-43 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 MC49_RS14365 b5ecceaa75eb59d7405909b168bd1ad9 463 TIGRFAM TIGR00905 2A0302: transporter, basic amino acid/polyamine antiporter (APA) family 3 462 1.5E-164 T 29-03-2018 IPR004754 Amino acid antiporter GO:0006865|GO:0016021 MC49_RS16420 55273b8e227429d6dbb9f34ccfa7aec8 189 Pfam PF01184 GPR1/FUN34/yaaH family 3 178 9.6E-46 T 29-03-2018 IPR000791 Acetate transporter GPR1/FUN34/SatP family GO:0016021 MC49_RS01230 fa32e80ddd766e76e5264b776aeb6e74 276 Pfam PF06067 Domain of unknown function (DUF932) 37 265 8.2E-61 T 29-03-2018 IPR026325 Protein of unknown function DUF932 MC49_RS17680 0316d5f2e7b723a6870767074633d94f 70 Pfam PF09926 Uncharacterized small protein (DUF2158) 7 65 1.6E-13 T 29-03-2018 IPR019226 Protein of unknown function DUF2158 MC49_RS08650 4988156aa6f832005ea157c29ce62bed 239 Gene3D G3DSA:3.40.30.10 142 239 2.0E-18 T 29-03-2018 MC49_RS08650 4988156aa6f832005ea157c29ce62bed 239 SUPERFAMILY SSF52833 142 235 2.8E-17 T 29-03-2018 IPR012336 Thioredoxin-like fold MC49_RS07015 ff8e2675ad2e4f585956cbb8ea9153c3 35 Pfam PF08049 IlvB leader peptide 10 35 2.2E-7 T 29-03-2018 IPR012566 IlvB leader peptide MC49_RS04020 b759c382f0f19e7269f8761667a24032 66 Pfam PF03889 Domain of unknown function 9 46 8.4E-24 T 29-03-2018 IPR005589 Protein of unknown function DUF331 MC49_RS14185 0ad6aa409814497c213a3684dba21e5b 334 Gene3D G3DSA:1.10.3470.10 11 307 3.2E-29 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like MC49_RS14185 0ad6aa409814497c213a3684dba21e5b 334 Pfam PF02653 Branched-chain amino acid transport system / permease component 40 301 3.4E-44 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 MC49_RS15720 ab091d391ae37717c7585af15ec08785 179 Pfam PF09831 Uncharacterized protein conserved in bacteria (DUF2058) 5 179 7.5E-58 T 29-03-2018 IPR018636 Protein of unknown function DUF2058 MC49_RS18550 d211149fe284630b400dcdb147fc585c 124 SMART SM00644 2 104 2.8E-14 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MC49_RS18550 d211149fe284630b400dcdb147fc585c 124 SUPERFAMILY SSF55846 6 118 4.32E-48 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MC49_RS18550 d211149fe284630b400dcdb147fc585c 124 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 10 105 2.7E-25 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MC49_RS18550 d211149fe284630b400dcdb147fc585c 124 Gene3D G3DSA:3.40.80.10 4 121 5.2E-40 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MC49_RS18345 bdf24475f0c89f1dd617ad6c299f17a2 473 Pfam PF13644 DKNYY family 53 236 1.6E-8 T 29-03-2018 IPR027375 DKNYY family MC49_RS03725 321e6e13c5f6847f8c0994a9bd701cae 63 Pfam PF13627 Prokaryotic lipoprotein-attachment site 11 29 1.2E-8 T 29-03-2018 IPR032831 Prokaryotic lipoprotein-attachment site MC49_RS06780 d0ee01bda2d4a4eb1963250ec8e55d0e 133 Gene3D G3DSA:1.10.10.10 3 76 8.5E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain MC49_RS02590 0b659691a8e1a27c620a660d588a7166 466 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 25 436 2.7E-38 T 29-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 MC49_RS02590 0b659691a8e1a27c620a660d588a7166 466 PIRSF PIRSF002744 1 465 3.1E-90 T 29-03-2018 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 MC49_RS03690 8929a2c41369ebbec00949a8f28bd46f 169 Pfam PF09335 SNARE associated Golgi protein 40 160 2.3E-11 T 29-03-2018 IPR032816 SNARE associated Golgi protein MC49_RS14660 9f796f7fa54bce3095503f5c0b0cff16 175 Pfam PF12883 Protein of unknown function (DUF3828) 30 174 1.6E-12 T 29-03-2018 IPR024289 Domain of unknown function DUF3828 MC49_RS17365 c512ea8cf8b2f4778a98bac0195e1a20 90 Pfam PF02583 Metal-sensitive transcriptional repressor 7 85 1.8E-20 T 29-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 MC49_RS16695 0563de5096a74cff93fbdcff0ca5cd69 93 Gene3D G3DSA:1.10.357.10 2 89 2.5E-4 T 29-03-2018 MC49_RS16695 0563de5096a74cff93fbdcff0ca5cd69 93 Pfam PF08891 YfcL protein 4 86 2.5E-36 T 29-03-2018 IPR014987 Uncharacterised protein family YfcL MC49_RS04780 c1a883ad855f753c59f4c2f4cd46d3fe 111 Pfam PF10625 Universal stress protein B (UspB) 1 107 5.3E-52 T 29-03-2018 IPR019598 Universal stress protein B MC49_RS09865 f27959d91de029b8f84af5d5383354a1 263 Pfam PF01578 Cytochrome C assembly protein 37 260 2.0E-35 T 29-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 MC49_RS00325 54003d8b0f2ffc01c0a5703090cd697e 110 Gene3D G3DSA:1.10.260.40 11 93 6.6E-4 T 29-03-2018 MC49_RS11000 473ad4ef2b663c6e897ed2ac104fb422 482 SUPERFAMILY SSF51735 1 294 2.49E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS11000 473ad4ef2b663c6e897ed2ac104fb422 482 Gene3D G3DSA:3.40.50.720 1 302 8.6E-23 T 29-03-2018 MC49_RS11000 473ad4ef2b663c6e897ed2ac104fb422 482 Pfam PF11066 Protein of unknown function (DUF2867) 332 463 2.0E-15 T 29-03-2018 IPR021295 Protein of unknown function DUF2867 MC49_RS11000 473ad4ef2b663c6e897ed2ac104fb422 482 Pfam PF13460 NAD(P)H-binding 10 137 5.1E-14 T 29-03-2018 IPR016040 NAD(P)-binding domain MC49_RS05455 41d9b71bb262ea55ea84a8a10226d146 77 Pfam PF08759 Glycosyltransferase GT-D fold 11 68 7.6E-11 T 29-03-2018 IPR014869 Glycosyltransferase GT-D fold MC49_RS12185 2834a76c6e9e4bb6b33b9e90e6a4615d 322 Pfam PF13413 Helix-turn-helix domain 18 75 2.3E-13 T 29-03-2018 MC49_RS12185 2834a76c6e9e4bb6b33b9e90e6a4615d 322 Gene3D G3DSA:1.10.260.40 7 87 1.2E-8 T 29-03-2018 MC49_RS12185 2834a76c6e9e4bb6b33b9e90e6a4615d 322 Pfam PF13464 Domain of unknown function (DUF4115) 243 316 4.3E-23 T 29-03-2018 IPR025194 Domain of unknown function DUF4115 MC49_RS11375 745e190f2869e047b4b82d4b22c7914e 113 SUPERFAMILY SSF47752 33 102 6.54E-26 T 29-03-2018 IPR024972 HNS-dependent expression A GO:0030288|GO:0071468 MC49_RS11375 745e190f2869e047b4b82d4b22c7914e 113 Hamap MF_00946 Acid stress chaperone HdeA [hdeA]. 1 108 34.386 T 29-03-2018 IPR024972 HNS-dependent expression A GO:0030288|GO:0071468 MC49_RS11375 745e190f2869e047b4b82d4b22c7914e 113 Pfam PF06411 HdeA/HdeB family 9 98 6.4E-19 T 29-03-2018 IPR010486 HNS-dependent expression A/B MC49_RS11375 745e190f2869e047b4b82d4b22c7914e 113 ProDom PD065392 HDEA PRECURSOR SIGNAL PERIPLASMIC 3D-STRUCTURE DIRECT 10K-S SEQUENCING 40 102 1.0E-15 T 29-03-2018 IPR024972 HNS-dependent expression A GO:0030288|GO:0071468 MC49_RS11375 745e190f2869e047b4b82d4b22c7914e 113 Gene3D G3DSA:1.10.890.10 29 103 1.3E-18 T 29-03-2018 MC49_RS01315 fb094c1468f07f77c2f5adeef961117a 393 Gene3D G3DSA:1.20.1630.10 41 336 8.8E-42 T 29-03-2018 MC49_RS01315 fb094c1468f07f77c2f5adeef961117a 393 Pfam PF03916 Polysulphide reductase, NrfD 46 329 5.9E-15 T 29-03-2018 IPR005614 NrfD family MC49_RS06720 24e4fa822e0a4265fe54ef4252abec38 69 Gene3D G3DSA:1.20.5.500 22 64 9.7E-4 T 29-03-2018 MC49_RS14825 87819c441a3151d261c27a3eaabf20ac 103 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 3 99 1.7E-16 T 29-03-2018 IPR008407 Branched-chain amino acid transport, AzlD MC49_RS17875 ad952f408d2a8add7c16d03c9e3ead44 442 TIGRFAM TIGR00814 stp: serine transporter 15 431 5.0E-161 T 29-03-2018 IPR004694 Hydroxy amino acid transporter GO:0005215|GO:0006810|GO:0016021 MC49_RS17875 ad952f408d2a8add7c16d03c9e3ead44 442 Hamap MF_01583 Threonine/serine transporter TdcC [tdcC]. 1 441 47.983 T 29-03-2018 IPR023726 Threonine/serine transporter TdcC GO:0015565|GO:0015826|GO:0016021|GO:0022889|GO:0032329 MC49_RS17875 ad952f408d2a8add7c16d03c9e3ead44 442 Pfam PF01490 Transmembrane amino acid transporter protein 23 432 3.8E-6 T 29-03-2018 IPR013057 Amino acid transporter, transmembrane domain MC49_RS14995 f924c223020c942318228e07de39d11b 529 Pfam PF06097 Bacterial protein of unknown function (DUF945) 1 473 1.2E-117 T 29-03-2018 IPR010352 Protein of unknown function DUF945 MC49_RS18615 bc31722c8f6c3d7d69c791b25e38ac74 174 Pfam PF05258 Protein of unknown function (DUF721) 20 90 4.2E-11 T 29-03-2018 IPR007922 Protein of unknown function DUF721/UPF0232 MC49_RS17710 f082af13a2d0febb69f98294317e8765 177 Pfam PF06530 Phage antitermination protein Q 21 107 2.4E-8 T 29-03-2018 IPR010534 Bacteriophage 933W, GpQ GO:0003677|GO:0060567 MC49_RS03300 3a851ddaadb8d91cbcb36f65b7a5981f 173 Gene3D G3DSA:3.30.1050.10 24 139 7.2E-17 T 29-03-2018 IPR003033 SCP2 sterol-binding domain MC49_RS03300 3a851ddaadb8d91cbcb36f65b7a5981f 173 SUPERFAMILY SSF55718 37 138 8.48E-22 T 29-03-2018 IPR003033 SCP2 sterol-binding domain MC49_RS03300 3a851ddaadb8d91cbcb36f65b7a5981f 173 PIRSF PIRSF025550 1 173 8.7E-80 T 29-03-2018 IPR016830 Uncharacterised conserved protein UCP025550, lipid carrier protein, YhbT MC49_RS03300 3a851ddaadb8d91cbcb36f65b7a5981f 173 Pfam PF02036 SCP-2 sterol transfer family 36 133 3.6E-19 T 29-03-2018 IPR003033 SCP2 sterol-binding domain MC49_RS17290 fe4fd5906769f742674541baa4054e58 334 Pfam PF04245 37-kD nucleoid-associated bacterial protein 10 324 3.5E-100 T 29-03-2018 IPR007358 Nucleoid-associated protein NdpA GO:0009295 MC49_RS17290 fe4fd5906769f742674541baa4054e58 334 Hamap MF_00730 Nucleoid-associated protein YejK [yejK]. 3 330 45.399 T 29-03-2018 IPR007358 Nucleoid-associated protein NdpA GO:0009295 MC49_RS10950 413873521dd91d797ac722450f7dd967 431 TIGRFAM TIGR00814 stp: serine transporter 14 416 4.3E-175 T 29-03-2018 IPR004694 Hydroxy amino acid transporter GO:0005215|GO:0006810|GO:0016021 MC49_RS10950 413873521dd91d797ac722450f7dd967 431 Pfam PF03222 Tryptophan/tyrosine permease family 26 392 1.6E-9 T 29-03-2018 IPR018227 Amino acid/polyamine transporter 2 GO:0003333 MC49_RS17510 42c60b984479a5154a28e52d18dc93f9 102 Pfam PF10109 Phage tail assembly chaperone proteins, E, or 41 or 14 12 89 1.0E-10 T 29-03-2018 IPR019289 Bacteriophage tail protein Gp41, putative MC49_RS02795 c2f39a6f5e86dffaba38c93e48597d25 199 ProDom PD038222 INVASION PLASMID OXYGEN-REGULATED III SECRETION MXIN TYPE SYSTEM PATHWAY ORGB 18 174 1.0E-6 T 29-03-2018 MC49_RS13680 0e1f63e75f1c7839049e9c2ea300bdab 299 Pfam PF05425 Copper resistance protein D 195 292 5.7E-16 T 29-03-2018 IPR008457 Copper resistance protein D GO:0016021 MC49_RS04855 cfb3e12ccb9dab35d21db05a67737f50 665 ProSitePatterns PS01303 BCCT family of transporters signature. 320 329 - T 29-03-2018 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 MC49_RS04855 cfb3e12ccb9dab35d21db05a67737f50 665 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 18 501 3.3E-193 T 29-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 MC49_RS04855 cfb3e12ccb9dab35d21db05a67737f50 665 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 56 502 2.6E-161 T 29-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 MC49_RS13500 86c401e0f535ed81ae3f4223964a0921 216 Pfam PF03591 AzlC protein 18 149 2.0E-32 T 29-03-2018 IPR011606 Branched-chain amino acid transport, permease MC49_RS13175 bd8cfb27c8caaf80de42c32ad89d41a8 138 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 90 102 3.7E-11 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MC49_RS13175 bd8cfb27c8caaf80de42c32ad89d41a8 138 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 51 61 3.7E-11 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MC49_RS13175 bd8cfb27c8caaf80de42c32ad89d41a8 138 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 62 73 3.7E-11 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MC49_RS13175 bd8cfb27c8caaf80de42c32ad89d41a8 138 Gene3D G3DSA:2.10.109.10 19 137 5.7E-26 T 29-03-2018 MC49_RS13175 bd8cfb27c8caaf80de42c32ad89d41a8 138 SUPERFAMILY SSF51306 14 135 6.1E-35 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MC49_RS13175 bd8cfb27c8caaf80de42c32ad89d41a8 138 Pfam PF00717 Peptidase S24-like 54 119 8.4E-12 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MC49_RS06860 c0e9e0584fe38c0fd07af6352000c335 113 PIRSF PIRSF030771 1 106 4.7E-32 T 29-03-2018 IPR011231 Bacteriophage VT1-Sakai, H0018 MC49_RS06860 c0e9e0584fe38c0fd07af6352000c335 113 Pfam PF09956 Uncharacterized conserved protein (DUF2190) 3 104 1.2E-17 T 29-03-2018 IPR011231 Bacteriophage VT1-Sakai, H0018 MC49_RS12240 b71c7c3ba0ae7aa5ac1872e2a9a49003 298 Pfam PF04261 Dyp-type peroxidase family 5 294 2.0E-85 T 29-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 MC49_RS12240 b71c7c3ba0ae7aa5ac1872e2a9a49003 298 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 5 294 3.1E-83 T 29-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 MC49_RS12240 b71c7c3ba0ae7aa5ac1872e2a9a49003 298 SUPERFAMILY SSF54909 1 296 2.86E-90 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel MC49_RS04585 49be65db48ff1e2e89072484b767ccda 481 Pfam PF03553 Na+/H+ antiporter family 168 479 2.6E-39 T 29-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 MC49_RS17525 1698f3bcbb6596aaa0d0b09030ef1192 160 Pfam PF06995 Phage P2 GpU 5 124 1.1E-41 T 29-03-2018 IPR009734 Myoviridae, GpU MC49_RS17525 1698f3bcbb6596aaa0d0b09030ef1192 160 PIRSF PIRSF029208 1 152 3.9E-52 T 29-03-2018 IPR016912 Bacteriophage P2, GpU MC49_RS09385 120e6ff3a6a41581e3acb58b2f5619e8 524 Gene3D G3DSA:3.20.20.70 11 468 1.4E-7 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MC49_RS17265 c6ee76c34e452eff6565f2795597841e 114 Pfam PF13989 YejG-like protein 6 108 4.3E-40 T 29-03-2018 IPR020489 Uncharacterised protein family YejG MC49_RS17265 c6ee76c34e452eff6565f2795597841e 114 ProDom PD073777 YEJG CYTOPLASMIC SIMILAR Y2914 YPO1269 STY2456 ECS3073 ESCHERICHIA COLI 1 114 2.0E-24 T 29-03-2018 IPR020489 Uncharacterised protein family YejG MC49_RS14755 e8003a2b761d0ef4d6e15610abf78df1 211 Pfam PF01810 LysE type translocator 17 208 8.6E-20 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MC49_RS03190 e4054002570632ef03761f3d107cbbc0 407 SUPERFAMILY SSF56601 59 379 1.04E-64 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like MC49_RS03190 e4054002570632ef03761f3d107cbbc0 407 Gene3D G3DSA:3.40.710.10 53 400 1.5E-68 T 29-03-2018 MC49_RS03190 e4054002570632ef03761f3d107cbbc0 407 Pfam PF00144 Beta-lactamase 70 381 6.8E-59 T 29-03-2018 IPR001466 Beta-lactamase-related MC49_RS17050 f860c7f273fa2b2529dd22e126ebbe5c 195 TIGRFAM TIGR02722 lp_: uncharacterized lipoprotein 2 192 6.1E-34 T 29-03-2018 IPR014094 Penicillin-binding protein activator LpoB MC49_RS17050 f860c7f273fa2b2529dd22e126ebbe5c 195 Gene3D G3DSA:3.40.50.10070 72 195 7.8E-10 T 29-03-2018 MC49_RS17050 f860c7f273fa2b2529dd22e126ebbe5c 195 Pfam PF13036 Peptidoglycan-synthase activator LpoB 53 191 1.3E-23 T 29-03-2018 IPR014094 Penicillin-binding protein activator LpoB MC49_RS02280 3b85729e3f7e7a3b3383d3bd87fdfa71 125 TIGRFAM TIGR03750 conj_TIGR03750: conjugative transfer region protein, TIGR03750 family 4 113 7.4E-38 T 29-03-2018 IPR021877 Protein of unknown function DUF3487 MC49_RS02280 3b85729e3f7e7a3b3383d3bd87fdfa71 125 Pfam PF11990 Protein of unknown function (DUF3487) 3 114 3.9E-38 T 29-03-2018 IPR021877 Protein of unknown function DUF3487 MC49_RS02905 e74f393a127c250cd8eef1016fe77ce0 245 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 6 236 3.8E-37 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 MC49_RS02905 e74f393a127c250cd8eef1016fe77ce0 245 SUPERFAMILY SSF51695 1 239 1.81E-67 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 MC49_RS02905 e74f393a127c250cd8eef1016fe77ce0 245 Gene3D G3DSA:3.20.20.190 1 241 1.1E-63 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 MC49_RS00260 e747a1b08227679e03d39b831ecb1bac 167 Pfam PF06530 Phage antitermination protein Q 17 100 2.4E-7 T 29-03-2018 IPR010534 Bacteriophage 933W, GpQ GO:0003677|GO:0060567 MC49_RS10490 f21ca944b2136ad4d039f72322909d7d 233 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 23 232 2.4E-59 T 29-03-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 MC49_RS10490 f21ca944b2136ad4d039f72322909d7d 233 Pfam PF04973 Nicotinamide mononucleotide transporter 24 228 4.1E-50 T 29-03-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 MC49_RS02975 33b55562d5520a844cd36b4588d232e8 330 Gene3D G3DSA:2.40.37.10 102 317 0.003 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MC49_RS04775 0ce94bde48614a3797ba61a9cccb9e42 496 Pfam PF01384 Phosphate transporter family 30 485 3.9E-88 T 29-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 MC49_RS14765 482da2d9041cd178d5d353073353461f 395 SUPERFAMILY SSF103473 5 383 7.98E-49 T 29-03-2018 IPR020846 Major facilitator superfamily domain MC49_RS14765 482da2d9041cd178d5d353073353461f 395 Pfam PF07690 Major Facilitator Superfamily 11 319 3.3E-23 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MC49_RS14765 482da2d9041cd178d5d353073353461f 395 Gene3D G3DSA:1.20.1250.20 196 393 1.8E-18 T 29-03-2018 MC49_RS14765 482da2d9041cd178d5d353073353461f 395 Gene3D G3DSA:1.20.1250.20 1 195 2.7E-18 T 29-03-2018 MC49_RS16630 919975f38d177c78ff627b794dcc40c4 223 Pfam PF09335 SNARE associated Golgi protein 49 176 2.3E-26 T 29-03-2018 IPR032816 SNARE associated Golgi protein MC49_RS06925 6b5f62d7450d974cf95c70e8d694e1ae 192 Pfam PF06805 Bacteriophage lambda tail assembly protein I 2 75 7.9E-12 T 29-03-2018 IPR010654 Bacteriophage lambda tail assembly I MC49_RS00140 2107b6ce5c2df8b0c94dabe3f984b28f 312 Pfam PF10547 P22_AR N-terminal domain 8 119 3.8E-40 T 29-03-2018 IPR018875 Antirepressor protein ANT, N-terminal MC49_RS00140 2107b6ce5c2df8b0c94dabe3f984b28f 312 PRINTS PR01994 Antirepressor protein ANT signature 26 47 1.7E-24 T 29-03-2018 IPR018875 Antirepressor protein ANT, N-terminal MC49_RS00140 2107b6ce5c2df8b0c94dabe3f984b28f 312 PRINTS PR01994 Antirepressor protein ANT signature 71 94 1.7E-24 T 29-03-2018 IPR018875 Antirepressor protein ANT, N-terminal MC49_RS00140 2107b6ce5c2df8b0c94dabe3f984b28f 312 PRINTS PR01994 Antirepressor protein ANT signature 95 117 1.7E-24 T 29-03-2018 IPR018875 Antirepressor protein ANT, N-terminal MC49_RS10330 59eaea862bae807a7a08ecc9fe5d9077 70 Pfam PF10725 Protein of unknown function (DUF2517) 4 63 2.3E-35 T 29-03-2018 IPR019663 Uncharacterised protein YbfA MC49_RS06825 28de87c79c1d05fde52f2791d0a38a46 73 ProDom PD288183 P16 LYTIC ECS4964 RZ1 2 71 2.0E-14 T 29-03-2018 IPR020307 Protein of unknown function P16 MC49_RS10430 e97b1fd2dec69c7c24b79bd7ac0c7b3d 135 SUPERFAMILY SSF54427 10 133 2.19E-26 T 29-03-2018 IPR032710 NTF2-like domain MC49_RS10430 e97b1fd2dec69c7c24b79bd7ac0c7b3d 135 Gene3D G3DSA:3.10.450.50 8 132 1.7E-29 T 29-03-2018 MC49_RS10430 e97b1fd2dec69c7c24b79bd7ac0c7b3d 135 PIRSF PIRSF029394 3 135 3.4E-25 T 29-03-2018 IPR016918 Uncharacterised conserved protein UCP029394 MC49_RS16800 a3a7c713280075cf5f9f8e95b2cfdf3a 64 Pfam PF16080 Bacteriophage holin family HP1 5 58 2.4E-28 T 29-03-2018 IPR032118 Bacteriophage holin HP1 family MC49_RS07870 5abaaf330673aadb90d3c3a2799a0192 195 PIRSF PIRSF004525 1 193 9.2E-44 T 29-03-2018 IPR016419 Prepilin peptidase-dependent protein B, predicted MC49_RS13710 69da6969b4533adb2bb5e9abe57f2b0e 116 Pfam PF04343 Protein of unknown function, DUF488 4 111 4.3E-30 T 29-03-2018 IPR007438 Protein of unknown function DUF488 MC49_RS04905 cb48c17d54b91193bc6f4671511fc4af 278 Pfam PF06067 Domain of unknown function (DUF932) 37 262 5.5E-55 T 29-03-2018 IPR026325 Protein of unknown function DUF932 MC49_RS16785 495c4ea238e3daaa0fd4040450af3adb 93 ProDom PD288183 P16 LYTIC ECS4964 RZ1 18 81 5.0E-6 T 29-03-2018 IPR020307 Protein of unknown function P16 MC49_RS01540 f8499471768bf0c2177645bfd90ed502 260 Pfam PF02405 Permease MlaE 46 256 1.4E-75 T 29-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 MC49_RS01540 f8499471768bf0c2177645bfd90ed502 260 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 5 258 7.3E-101 T 29-03-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria MC49_RS00965 47bad0ae76274b299e40a9d46afa74b4 403 Pfam PF04143 Sulphur transport 237 390 1.3E-24 T 29-03-2018 IPR007272 Sulphur transport domain MC49_RS00965 47bad0ae76274b299e40a9d46afa74b4 403 Pfam PF04143 Sulphur transport 4 160 3.5E-25 T 29-03-2018 IPR007272 Sulphur transport domain MC49_RS13450 7274a3f26d0542ec0b5eaedc335a4922 72 ProDom PD052686 LIPOPROTEIN INDUCIBLE OSMOTICALLY B PRECURSOR SIGNAL MEMBRANE PALMITATE TRANSMEMBRANE SURFACE 23 72 0.002 T 29-03-2018 MC49_RS13450 7274a3f26d0542ec0b5eaedc335a4922 72 Pfam PF05433 Glycine zipper 2TM domain 34 70 9.9E-8 T 29-03-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 MC49_RS14430 2db941377230e2f3398ee92860c5390c 301 Pfam PF03547 Membrane transport protein 152 296 2.4E-10 T 29-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 MC49_RS14820 159d16504877f7397b67093ad0b130d2 238 Pfam PF03591 AzlC protein 27 163 7.9E-34 T 29-03-2018 IPR011606 Branched-chain amino acid transport, permease MC49_RS18035 70a2612ab5a7541d69938ca1b2703a54 115 Pfam PF11225 Protein of unknown function (DUF3024) 60 112 7.7E-12 T 29-03-2018 IPR021388 Bacteriophage 933W, L0084 MC49_RS16585 644ce3df48a73c002865009cfc034b58 693 Gene3D G3DSA:3.30.2010.10 215 314 4.1E-10 T 29-03-2018 MC49_RS16585 644ce3df48a73c002865009cfc034b58 693 Pfam PF01435 Peptidase family M48 232 455 2.9E-15 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 MC49_RS10970 3ba273204770132c6ce32df1c144593a 162 Pfam PF10722 Putative bacterial sensory transduction regulator 6 126 4.7E-12 T 29-03-2018 IPR019660 Putative sensory transduction regulator YbjN MC49_RS16700 b4818ccd5b98cdaeef675a04e9370bb6 183 Pfam PF04315 Elongation factor P hydroxylase 12 175 5.9E-78 T 29-03-2018 IPR007411 Elongation factor P hydroxylase MC49_RS05700 020ea8830eb846735fdcb5469e830e12 423 TIGRFAM TIGR03573 WbuX: N-acetyl sugar amidotransferase 1 347 2.8E-115 T 29-03-2018 IPR020022 N-acetyl sugar amidotransferase MC49_RS13615 6b90d7e99588b04fc7e6f53806f507c0 189 Pfam PF02659 Putative manganese efflux pump 33 184 8.2E-53 T 29-03-2018 IPR003810 Putative manganese efflux pump MC49_RS13615 6b90d7e99588b04fc7e6f53806f507c0 189 Hamap MF_01521 Probable manganese efflux pump MntP [mntP]. 1 187 25.322 T 29-03-2018 IPR022929 Putative manganese efflux pump MntP MC49_RS05610 7aadae629709cf9a0b61fc3f1a24fdac 325 Gene3D G3DSA:3.20.20.370 3 325 1.2E-26 T 29-03-2018 MC49_RS05610 7aadae629709cf9a0b61fc3f1a24fdac 325 SUPERFAMILY SSF88713 30 180 3.34E-8 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MC49_RS15490 d40f7ae0137619d7640b6dcd5e6f1fb1 101 Pfam PF03891 Domain of unknown function (DUF333) 53 95 4.2E-10 T 29-03-2018 IPR005590 Protein of unknown function DUF333 MC49_RS01350 7c67632815289fb3db5a90cfd3c77716 226 Pfam PF09335 SNARE associated Golgi protein 48 173 6.1E-21 T 29-03-2018 IPR032816 SNARE associated Golgi protein MC49_RS17640 a586278415c5bae031170e991d9b1b23 355 Pfam PF09950 Uncharacterized protein conserved in bacteria (DUF2184) 113 297 4.3E-12 T 29-03-2018 IPR020049 Protein of unknown function DUF2184 MC49_RS09355 57b9788d4e5a1c120955fc66166d9e77 169 SUPERFAMILY SSF58113 34 159 8.11E-6 T 29-03-2018 MC49_RS09355 57b9788d4e5a1c120955fc66166d9e77 169 Gene3D G3DSA:1.20.120.20 22 169 7.2E-11 T 29-03-2018 MC49_RS13425 379fc3810c8a4650f775205242c330fe 410 Gene3D G3DSA:2.10.10.20 72 118 7.2E-5 T 29-03-2018 MC49_RS07955 ee8c0c3097737349c274650a15257a82 126 Pfam PF04241 Protein of unknown function (DUF423) 15 101 5.1E-22 T 29-03-2018 IPR006696 Protein of unknown function DUF423 MC49_RS02515 3dbccf65ca472486957ecfdad434fbac 210 Pfam PF00419 Fimbrial protein 57 209 3.7E-15 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS02515 3dbccf65ca472486957ecfdad434fbac 210 SUPERFAMILY SSF49401 57 209 3.08E-25 T 29-03-2018 IPR008966 Adhesion domain MC49_RS02515 3dbccf65ca472486957ecfdad434fbac 210 Gene3D G3DSA:2.60.40.1090 55 209 1.2E-29 T 29-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 MC49_RS13420 d9f3841f27413b4072a3427ba3359e82 220 Pfam PF11041 Protein of unknown function (DUF2612) 15 196 1.0E-56 T 29-03-2018 IPR021283 Protein of unknown function DUF2612 MC49_RS11890 6aba876e0c55d3527dfad4b2e29e92ee 451 Pfam PF06812 ImpA, N-terminal, type VI secretion system 14 113 1.3E-18 T 29-03-2018 IPR010657 ImpA, N-terminal MC49_RS11890 6aba876e0c55d3527dfad4b2e29e92ee 451 Pfam PF12486 Type VI secretion system, EvfB, or VasL 290 435 5.3E-40 T 29-03-2018 IPR021069 ImpA, C-terminal MC49_RS03155 117eb32a4c2146638868c0a28c685eac 453 Gene3D G3DSA:3.40.50.620 150 383 3.7E-10 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MC49_RS03005 7addbe51296ac9ef847359fc08869820 262 Pfam PF11299 Protein of unknown function (DUF3100) 19 248 5.9E-89 T 29-03-2018 IPR021450 Protein of unknown function DUF3100 MC49_RS14020 8a18241330b7eeb4cf8dd00559fabb38 724 Pfam PF11308 Glycosyl hydrolases related to GH101 family, GH129 369 686 2.5E-125 T 29-03-2018 IPR021459 Glycosyl hydrolases related to GH101 family, GHL1-GHL3 MC49_RS16095 367384aac7e58652a0275d7886dfc45d 65 Hamap MF_01566 UPF0370 protein YpfN [ypfN]. 1 62 26.016 T 29-03-2018 IPR020910 Uncharacterised protein family UPF0370 MC49_RS16095 367384aac7e58652a0275d7886dfc45d 65 Pfam PF13980 Uncharacterised protein family (UPF0370) 1 61 3.4E-36 T 29-03-2018 IPR020910 Uncharacterised protein family UPF0370 MC49_RS18205 c06cb6344e08ed3c99357a6da375fd92 434 Pfam PF00860 Permease family 10 392 5.9E-63 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 MC49_RS13125 1ae9e40f389d13ec23189df328ad6895 109 Pfam PF05939 Phage minor tail protein 3 108 1.3E-30 T 29-03-2018 IPR010265 Bacteriophage lambda, GpM, minor tail MC49_RS07210 5c7c56af609a5f53a24874ca17d066bb 139 Pfam PF07007 Lysozyme inhibitor LprI 42 136 1.4E-15 T 29-03-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal MC49_RS13610 eed1b74bca9fb580036f2cb06c09e45c 273 SUPERFAMILY SSF53335 6 253 1.53E-44 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MC49_RS13610 eed1b74bca9fb580036f2cb06c09e45c 273 PIRSF PIRSF018249 1 272 3.0E-84 T 29-03-2018 IPR016718 rRNA (guanine-N1-)-methyltransferase A, predicted GO:0008168 MC49_RS13610 eed1b74bca9fb580036f2cb06c09e45c 273 Gene3D G3DSA:3.40.50.150 3 273 9.2E-57 T 29-03-2018 MC49_RS13610 eed1b74bca9fb580036f2cb06c09e45c 273 Pfam PF13847 Methyltransferase domain 87 201 6.0E-13 T 29-03-2018 IPR025714 Methyltransferase domain MC49_RS06685 a51d47592b86a5939e0ff658a2168692 85 Pfam PF11112 Pyocin activator protein PrtN 3 75 2.7E-23 T 29-03-2018 IPR020518 Transcription regulator PrtN GO:0006355 MC49_RS11865 96493bac2873312dda6d9f951afb40c5 139 Pfam PF06836 Protein of unknown function (DUF1240) 47 138 6.4E-12 T 29-03-2018 IPR010665 Protein of unknown function DUF1240 MC49_RS11615 8a36edfdba1f45186f2d7157107b2eb1 164 Pfam PF04463 Protein of unknown function (DUF523) 3 146 3.3E-41 T 29-03-2018 IPR007553 Domain of unknown function DUF523 MC49_RS17345 71397c3a04deb12fac39427ea298df40 183 Pfam PF09335 SNARE associated Golgi protein 29 145 4.8E-14 T 29-03-2018 IPR032816 SNARE associated Golgi protein MC49_RS16110 3bb9a0e17ae93fd9a49ed12195c6a2a2 295 Pfam PF04228 Putative neutral zinc metallopeptidase 1 291 1.2E-130 T 29-03-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative MC49_RS05265 d940e7fc4d2c7aeffa7e2622e91cc9e2 192 Pfam PF09937 Uncharacterized protein conserved in bacteria (DUF2169) 23 167 1.7E-31 T 29-03-2018 IPR018683 Domain of unknown function DUF2169 MC49_RS14340 b4353194b16b75417836cf1a8f53de33 869 Pfam PF11739 Dicarboxylate transport 659 860 3.5E-59 T 29-03-2018 IPR021730 Dicarboxylate transport MC49_RS05960 cf2ab5171ec9893e66cfce00915c5e7d 71 SUPERFAMILY SSF47413 5 37 1.01E-5 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 MC49_RS05960 cf2ab5171ec9893e66cfce00915c5e7d 71 Pfam PF13693 Winged helix-turn-helix DNA-binding 4 39 1.8E-9 T 29-03-2018 MC49_RS18245 0eda1ebd43c98fa3bf7e2c637771931d 70 Pfam PF04325 Protein of unknown function (DUF465) 19 66 1.5E-13 T 29-03-2018 IPR007420 Protein of unknown function DUF465 MC49_RS01870 2ac350f9f28aea2b0c4104764ceef249 95 Pfam PF06611 Protein of unknown function (DUF1145) 3 58 1.3E-23 T 29-03-2018 IPR009525 Protein of unknown function DUF1145 MC49_RS06840 bf2036d4bee2ae577aafab04bdd3a9d9 704 Pfam PF05876 Phage terminase large subunit (GpA) 35 645 4.8E-186 T 29-03-2018 IPR008866 Bacteriophage lambda, GpA MC49_RS00105 fe855abba13121ae41a2e4ab53435084 635 SUPERFAMILY SSF51126 213 483 2.67E-6 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor MC49_RS13845 4bcd648f13bbdac722421b4993f89867 331 Gene3D G3DSA:1.10.3470.10 34 318 1.3E-26 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like MC49_RS13845 4bcd648f13bbdac722421b4993f89867 331 Pfam PF02653 Branched-chain amino acid transport system / permease component 40 311 2.3E-42 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 MC49_RS15195 f99a99f8d2c383ac04969d0af7228115 189 Pfam PF14317 YcxB-like protein 112 172 4.8E-6 T 29-03-2018 IPR025588 YcxB-like protein MC49_RS04565 bb2c21df21c101fb6ecba71b353b6914 167 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 24 154 3.2E-32 T 29-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component MC49_RS00080 3d0ddfec3993437b5eebf4def1685013 121 Pfam PF06953 Arsenical resistance operon trans-acting repressor ArsD 1 121 2.3E-48 T 29-03-2018 IPR010712 Arsenical-resistance operon trans-acting repressor ArsD GO:0003677|GO:0045892|GO:0046685 MC49_RS01780 71e387d2be9bdfc18a39022f59782a81 29 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 6 29 6.8E-9 T 29-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 MC49_RS01780 71e387d2be9bdfc18a39022f59782a81 29 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 7 29 5.5E-7 T 29-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 MC49_RS11990 071acb3abb5483f87d98b0438c0317cf 68 Pfam PF11903 ParD-like antitoxin of type II bacterial toxin-antitoxin system 2 58 1.2E-22 T 29-03-2018 IPR021831 ParD-like antitoxin of type II bacterial toxin-antitoxin system MC49_RS17120 0d56dc406078acf8681a84134af8f0c7 174 Pfam PF02620 Uncharacterized ACR, COG1399 62 171 5.0E-17 T 29-03-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD MC49_RS04975 22e906d042c7e02baec09ff54e21f32b 128 SUPERFAMILY SSF55021 70 107 4.84E-5 T 29-03-2018 MC49_RS04975 22e906d042c7e02baec09ff54e21f32b 128 Gene3D G3DSA:3.30.2130.10 34 123 2.2E-4 T 29-03-2018 MC49_RS12610 6081593c5923362a0e5a776ff4f98a3c 161 Pfam PF03748 Flagellar basal body-associated protein FliL 61 159 2.3E-18 T 29-03-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 MC49_RS09580 c30b0a1834bea27839ec4b4f84a6a73b 108 Pfam PF04320 Protein with unknown function (DUF469) 7 107 1.4E-39 T 29-03-2018 IPR007416 Protein of unknown function DUF469 MC49_RS07965 1b9e395ea6e5f0e8e3a4c91436f22105 231 Pfam PF12158 Protein of unknown function (DUF3592) 8 130 1.2E-16 T 29-03-2018 IPR021994 Protein of unknown function DUF3592 MC49_RS11370 6d8336748796a365180f6d2d15b62c4e 316 Pfam PF13515 Fusaric acid resistance protein-like 187 307 4.0E-12 T 29-03-2018 MC49_RS12795 d2957e99b6974d1c698b09588e36b245 223 Pfam PF01066 CDP-alcohol phosphatidyltransferase 33 107 1.3E-5 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MC49_RS02195 b67c9914e710556055617aa9b29430d9 393 Pfam PF11876 Protein of unknown function (DUF3396) 130 316 6.1E-49 T 29-03-2018 IPR021815 Protein of unknown function DUF3396 MC49_RS16165 ee5373db004422a2a0e1edfa180a2641 360 Pfam PF01594 AI-2E family transporter 20 345 1.9E-78 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like MC49_RS01255 9c450672b38cf32ec245e628c65867d5 354 Pfam PF06250 Protein of unknown function (DUF1016) 19 335 2.1E-110 T 29-03-2018 IPR009362 Protein of unknown function DUF1016 MC49_RS10725 0d1e35c025d1a427bf206116eafc54be 415 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 11 397 1.6E-69 T 29-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 MC49_RS12920 7e6aa425eba4fa3ade0179248220fa6f 113 Pfam PF11225 Protein of unknown function (DUF3024) 62 112 1.4E-8 T 29-03-2018 IPR021388 Bacteriophage 933W, L0084