locus-tag	class	description
FR932_RS00040	COG1192	Involved in chromosome partitioning
FR932_RS00145	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FR932_RS00150	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FR932_RS00155	COG0747	negative chemotaxis
FR932_RS00160	COG0601	transmembrane transport
FR932_RS00165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FR932_RS00170	COG0444	Belongs to the ABC transporter superfamily
FR932_RS00175	COG4608	Belongs to the ABC transporter superfamily
FR932_RS00180	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FR932_RS00185	COG0142	geranyltranstransferase activity
FR932_RS00195	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FR932_RS00200	COG1360	Flagellar Motor Protein
FR932_RS00210	COG0601	transmembrane transport
FR932_RS00215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FR932_RS00230	COG0737	Belongs to the 5'-nucleotidase family
FR932_RS00235	COG2356	endonuclease I
FR932_RS00250	COG0737	Belongs to the 5'-nucleotidase family
FR932_RS00265	COG1869	D-ribose catabolic process
FR932_RS00270	COG1129	ABC transporter
FR932_RS00275	COG1172	Belongs to the binding-protein-dependent transport system permease family
FR932_RS00280	COG1879	ABC-type sugar transport system periplasmic component
FR932_RS00285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FR932_RS00290	COG1609	Transcriptional regulator
FR932_RS00340	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FR932_RS00345	COG2867	negative regulation of translational initiation
FR932_RS00350	COG2914	Belongs to the UPF0125 (RnfH) family
FR932_RS00355	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FR932_RS00360	COG0497	DNA recombination
FR932_RS00370	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FR932_RS00375	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FR932_RS00380	COG0739	heme binding
FR932_RS00385	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FR932_RS00400	COG1534	Rna-binding protein
FR932_RS00405	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FR932_RS00410	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FR932_RS00415	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FR932_RS00420	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FR932_RS00425	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FR932_RS00440	COG0779	Required for maturation of 30S ribosomal subunits
FR932_RS00445	COG0195	Participates in both transcription termination and antitermination
FR932_RS00450	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FR932_RS00455	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FR932_RS00460	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FR932_RS00465	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FR932_RS00470	COG1185	polyribonucleotide nucleotidyltransferase activity
FR932_RS00480	COG0826	peptidase U32
FR932_RS00485	COG0826	peptidase U32
FR932_RS00490	COG3154	lipid carrier protein
FR932_RS00500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FR932_RS00505	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FR932_RS00510	COG0826	peptidase U32
FR932_RS00515	COG1283	sodium-dependent phosphate transmembrane transporter activity
FR932_RS00515	COG1283	sodium-dependent phosphate transmembrane transporter activity
FR932_RS00520	COG2974	May be involved in recombination
FR932_RS00525	COG0745	RESPONSE REGULATOR receiver
FR932_RS00530	COG5002	protein histidine kinase activity
FR932_RS00540	COG2223	nitrite transmembrane transporter activity
FR932_RS00550	COG0573	inorganic phosphate transmembrane transporter activity
FR932_RS00555	COG0573	inorganic phosphate transmembrane transporter activity
FR932_RS00560	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FR932_RS00565	COG0704	Plays a role in the regulation of phosphate uptake
FR932_RS00575	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FR932_RS00585	COG0330	HflC and HflK could
FR932_RS00600	COG1115	amino acid carrier protein
FR932_RS00605	COG0626	cystathionine gamma-synthase activity
FR932_RS00635	COG0702	epimerase
FR932_RS00640	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FR932_RS00645	COG1678	Uncharacterized ACR, COG1678
FR932_RS00650	COG0189	ligase activity
FR932_RS00655	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FR932_RS00660	COG3048	D-serine ammonia-lyase activity
FR932_RS00665	COG0583	DNA-binding transcription factor activity
FR932_RS00680	COG2356	endonuclease I
FR932_RS00715	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FR932_RS00720	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FR932_RS00725	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FR932_RS00750	COG1489	DNA binding
FR932_RS00760	COG1643	Atp-dependent helicase
FR932_RS00765	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FR932_RS00775	COG0739	heme binding
FR932_RS00790	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FR932_RS00805	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FR932_RS00850	COG0628	permease
FR932_RS00855	COG2154	pterin-4-alpha-carbinolamine dehydratase
FR932_RS00865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FR932_RS00875	COG2165	general secretion pathway protein
FR932_RS00880	COG2165	general secretion pathway protein
FR932_RS00885	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FR932_RS00900	COG3291	Pkd domain containing protein
FR932_RS00905	COG2716	regulation of RNA biosynthetic process
FR932_RS00910	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FR932_RS00915	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FR932_RS00925	COG1876	peptidase activity
FR932_RS00935	COG0564	pseudouridine synthase activity
FR932_RS00940	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FR932_RS00945	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FR932_RS00950	COG0287	Prephenate dehydrogenase
FR932_RS00950	COG1605	Chorismate mutase
FR932_RS00955	COG0077	Prephenate dehydratase
FR932_RS00955	COG1605	Chorismate mutase
FR932_RS00960	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FR932_RS00970	COG4166	transmembrane transport
FR932_RS00975	COG4174	ABC transporter (Permease)
FR932_RS00980	COG4239	(ABC) transporter, permease
FR932_RS00985	COG4172	Belongs to the ABC transporter superfamily
FR932_RS00990	COG0840	transmembrane signaling receptor activity
FR932_RS01005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FR932_RS01015	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FR932_RS01025	COG0493	'glutamate synthase
FR932_RS01030	COG0070	glutamate synthase
FR932_RS01030	COG0067	glutamate synthase
FR932_RS01030	COG0069	glutamate synthase activity
FR932_RS01035	COG2203	Gaf domain
FR932_RS01035	COG3706	GGDEF domain
FR932_RS01035	COG4251	negative regulation of phosphorylation
FR932_RS01035	COG5001	Diguanylate cyclase
FR932_RS01040	COG2198	Histidine kinase
FR932_RS01040	COG0784	Response regulator, receiver
FR932_RS01040	COG5002	protein histidine kinase activity
FR932_RS01055	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FR932_RS01075	COG0788	formyltetrahydrofolate deformylase activity
FR932_RS01080	COG3012	SEC-C Motif Domain Protein
FR932_RS01090	COG0429	hydrolase of the alpha beta-hydrolase fold
FR932_RS01140	COG2200	EAL domain
FR932_RS01165	COG3604	Transcriptional regulator
FR932_RS01170	COG1773	rubredoxin
FR932_RS01170	COG0426	domain, Protein
FR932_RS01180	COG0346	lactoylglutathione lyase activity
FR932_RS01195	COG0300	oxidoreductase activity
FR932_RS01210	COG1349	DNA-binding transcription factor activity
FR932_RS01215	COG1192	Involved in chromosome partitioning
FR932_RS01220	COG0408	coproporphyrinogen oxidase activity
FR932_RS01225	COG0668	transmembrane transport
FR932_RS01235	COG0494	nUDIX hydrolase
FR932_RS01255	COG1960	acyl-CoA dehydrogenase activity
FR932_RS01260	COG0469	pyruvate kinase activity
FR932_RS01265	COG1737	Transcriptional regulator
FR932_RS01270	COG1760	l-serine dehydratase
FR932_RS01290	COG0784	Response regulator, receiver
FR932_RS01290	COG0835	chemotaxis
FR932_RS01300	COG1815	bacterial-type flagellum-dependent cell motility
FR932_RS01320	COG4786	Flagellar basal body rod
FR932_RS01330	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FR932_RS01335	COG1706	bacterial-type flagellum-dependent cell motility
FR932_RS01340	COG3951	Flagellar rod assembly protein muramidase FlgJ
FR932_RS01340	COG1705	Flagellar rod assembly protein muramidase FlgJ
FR932_RS01355	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FR932_RS01365	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FR932_RS01370	COG1334	flagellar protein FlaG
FR932_RS01375	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FR932_RS01395	COG2814	Major facilitator Superfamily
FR932_RS01400	COG1058	Belongs to the CinA family
FR932_RS01400	COG1546	Belongs to the CinA family
FR932_RS01415	COG0583	DNA-binding transcription factor activity
FR932_RS01425	COG1760	l-serine dehydratase
FR932_RS01430	COG0109	protoheme IX farnesyltransferase activity
FR932_RS01465	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FR932_RS01470	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FR932_RS01470	COG1565	acr, cog1565
FR932_RS01480	COG0544	peptidyl-prolyl cis-trans isomerase activity
FR932_RS01485	COG0740	serine-type endopeptidase activity
FR932_RS01490	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FR932_RS01495	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FR932_RS01500	COG0776	regulation of translation
FR932_RS01505	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FR932_RS01515	COG4172	Belongs to the ABC transporter superfamily
FR932_RS01525	COG4171	peptide transport system, permease
FR932_RS01530	COG4168	peptide transport system, permease
FR932_RS01555	COG0259	pyridoxamine-phosphate oxidase activity
FR932_RS01560	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FR932_RS01565	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FR932_RS01575	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FR932_RS01595	COG0730	response to heat
FR932_RS01600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FR932_RS01615	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FR932_RS01620	COG0436	Aminotransferase
FR932_RS01630	COG0584	glycerophosphoryl diester phosphodiesterase
FR932_RS01645	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FR932_RS01650	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FR932_RS01650	COG0574	Belongs to the PEP-utilizing enzyme family
FR932_RS01660	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FR932_RS01665	COG0277	FAD linked oxidase domain protein
FR932_RS01665	COG0247	lactate metabolic process
FR932_RS01675	COG0676	glucose-6-phosphate 1-epimerase activity
FR932_RS01680	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FR932_RS01700	COG3139	Protein of unknown function (DUF1315)
FR932_RS01705	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FR932_RS01710	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FR932_RS01715	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FR932_RS01720	COG0492	ferredoxin-NADP+ reductase activity
FR932_RS01730	COG0531	amino acid
FR932_RS01730	COG1674	ftsk spoiiie
FR932_RS01740	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FR932_RS01745	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FR932_RS01750	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FR932_RS01755	COG2920	part of a sulfur-relay system
FR932_RS01760	COG0670	Belongs to the BI1 family
FR932_RS01790	COG2197	response regulator
FR932_RS01795	COG0322	excinuclease ABC activity
FR932_RS01800	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FR932_RS01860	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FR932_RS01865	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FR932_RS01885	COG1677	Flagellar hook-basal body complex protein FliE
FR932_RS01895	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FR932_RS01945	COG1987	bacterial-type flagellum assembly
FR932_RS01960	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FR932_RS01985	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FR932_RS01990	COG0643	Histidine kinase
FR932_RS01990	COG0784	Response regulator, receiver
FR932_RS01990	COG2198	Histidine kinase
FR932_RS01995	COG2201	protein-glutamate methylesterase activity
FR932_RS02000	COG1192	Involved in chromosome partitioning
FR932_RS02010	COG0835	chemotaxis
FR932_RS02020	COG4133	protoheme IX ABC transporter activity
FR932_RS02025	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FR932_RS02030	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FR932_RS02035	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FR932_RS02040	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FR932_RS02045	COG1138	Cytochrome C-type biogenesis protein
FR932_RS02050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FR932_RS02060	COG4235	cytochrome complex assembly
FR932_RS02060	COG3088	subunit of a heme lyase
FR932_RS02065	COG2850	peptidyl-arginine hydroxylation
FR932_RS02070	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FR932_RS02080	COG0513	Belongs to the DEAD box helicase family
FR932_RS02090	COG0513	Belongs to the DEAD box helicase family
FR932_RS02095	COG0247	lactate metabolic process
FR932_RS02105	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FR932_RS02110	COG0583	DNA-binding transcription factor activity
FR932_RS02115	COG4221	oxidoreductase activity
FR932_RS02125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FR932_RS02130	COG4597	amino acid ABC transporter
FR932_RS02135	COG0765	amino acid transport
FR932_RS02140	COG1126	abc transporter atp-binding protein
FR932_RS02150	COG3634	alkyl hydroperoxide reductase activity
FR932_RS02165	COG0456	acetyltransferase
FR932_RS02175	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FR932_RS02185	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FR932_RS02190	COG2915	High frequency lysogenization protein hflD homolog
FR932_RS02195	COG0482	sulfurtransferase activity
FR932_RS02200	COG1187	pseudouridine synthase activity
FR932_RS02205	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FR932_RS02205	COG2755	lipolytic protein G-D-S-L family
FR932_RS02220	COG3118	belongs to the thioredoxin family
FR932_RS02235	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FR932_RS02250	COG2770	Histidine kinase
FR932_RS02250	COG3437	response regulator, receiver
FR932_RS02260	COG3300	MHYT domain
FR932_RS02260	COG5001	Diguanylate cyclase
FR932_RS02265	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FR932_RS02285	COG1902	pentaerythritol trinitrate reductase activity
FR932_RS02290	COG2814	Major facilitator Superfamily
FR932_RS02295	COG0583	DNA-binding transcription factor activity
FR932_RS02300	COG0243	molybdopterin cofactor binding
FR932_RS02305	COG1272	protein, Hemolysin III
FR932_RS02315	COG3101	peptidyl-lysine hydroxylation
FR932_RS02330	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FR932_RS02335	COG5380	lipid catabolic process
FR932_RS02350	COG0745	RESPONSE REGULATOR receiver
FR932_RS02355	COG2205	protein histidine kinase activity
FR932_RS02370	COG4580	involved in the transport of maltose and maltodextrins
FR932_RS02390	COG3842	ATPase activity
FR932_RS02400	COG1175	transmembrane transport
FR932_RS02405	COG3833	ABC-type maltose transport systems, permease component
FR932_RS02430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FR932_RS02435	COG0784	Response regulator, receiver
FR932_RS02435	COG2205	protein histidine kinase activity
FR932_RS02445	COG2909	trisaccharide binding
FR932_RS02455	COG0058	SHG alpha-glucan phosphorylase activity
FR932_RS02460	COG1640	4-alpha-glucanotransferase
FR932_RS02480	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FR932_RS02490	COG0659	secondary active sulfate transmembrane transporter activity
FR932_RS02495	COG0583	DNA-binding transcription factor activity
FR932_RS02510	COG0583	DNA-binding transcription factor activity
FR932_RS02515	COG0006	proline dipeptidase activity
FR932_RS02530	COG3791	Glutathione-dependent formaldehyde-activating
FR932_RS02540	COG0840	transmembrane signaling receptor activity
FR932_RS02545	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FR932_RS02545	COG0678	peroxiredoxin activity
FR932_RS02555	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FR932_RS02565	COG1215	transferase activity, transferring glycosyl groups
FR932_RS02635	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FR932_RS02640	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FR932_RS02645	COG0583	DNA-binding transcription factor activity
FR932_RS02660	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FR932_RS02665	COG1609	Transcriptional regulator
FR932_RS02670	COG3265	gluconokinase activity
FR932_RS02675	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FR932_RS02680	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FR932_RS02755	COG1012	belongs to the aldehyde dehydrogenase family
FR932_RS02760	COG1733	regulation of RNA biosynthetic process
FR932_RS02770	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FR932_RS02780	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FR932_RS02795	COG1757	Na H antiporter
FR932_RS02805	COG2130	NADP-dependent
FR932_RS02830	COG0405	Gamma-glutamyltransferase
FR932_RS02835	COG4989	oxidoreductase activity
FR932_RS02840	COG0824	Thioesterase
FR932_RS02850	COG5001	Diguanylate cyclase
FR932_RS02855	COG1349	DNA-binding transcription factor activity
FR932_RS02865	COG1454	alcohol dehydrogenase
FR932_RS02865	COG1012	belongs to the aldehyde dehydrogenase family
FR932_RS02870	COG1528	Iron-storage protein
FR932_RS02890	COG4067	protein conserved in archaea
FR932_RS02890	COG0189	ligase activity
FR932_RS02895	COG4067	protein conserved in archaea
FR932_RS02895	COG0189	ligase activity
FR932_RS02900	COG0500	methyltransferase
FR932_RS02905	COG2226	methyltransferase
FR932_RS02920	COG0583	DNA-binding transcription factor activity
FR932_RS02945	COG3706	GGDEF domain
FR932_RS02950	COG1067	ATP-dependent peptidase activity
FR932_RS02960	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FR932_RS02985	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FR932_RS02990	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FR932_RS02995	COG0730	response to heat
FR932_RS03000	COG0583	DNA-binding transcription factor activity
FR932_RS03005	COG1609	Transcriptional regulator
FR932_RS03015	COG1105	Belongs to the carbohydrate kinase PfkB family
FR932_RS03020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FR932_RS03020	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FR932_RS03020	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FR932_RS03055	COG0328	RNA-DNA hybrid ribonuclease activity
FR932_RS03080	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FR932_RS03085	COG0632	four-way junction helicase activity
FR932_RS03090	COG2255	four-way junction helicase activity
FR932_RS03095	COG0824	Thioesterase
FR932_RS03100	COG0811	peptide transport
FR932_RS03120	COG2885	chlorophyll binding
FR932_RS03210	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FR932_RS03220	COG2917	probably involved in intracellular septation
FR932_RS03245	COG0735	belongs to the Fur family
FR932_RS03255	COG0716	FMN binding
FR932_RS03270	COG0596	Alpha beta hydrolase
FR932_RS03275	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FR932_RS03285	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
FR932_RS03290	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FR932_RS03305	COG0537	adenosine 5'-monophosphoramidase activity
FR932_RS03320	COG1472	Belongs to the glycosyl hydrolase 3 family
FR932_RS03330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FR932_RS03345	COG0101	tRNA pseudouridine synthase activity
FR932_RS03350	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FR932_RS03355	COG0285	dihydrofolate synthase activity
FR932_RS03360	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FR932_RS03365	COG1286	toxin biosynthetic process
FR932_RS03370	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FR932_RS03375	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FR932_RS03380	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FR932_RS03385	COG0215	cysteine-tRNA ligase activity
FR932_RS03390	COG0545	Peptidyl-prolyl cis-trans isomerase
FR932_RS03395	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FR932_RS03420	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FR932_RS03430	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FR932_RS03435	COG1028	Short-chain dehydrogenase reductase Sdr
FR932_RS03445	COG3806	Anti-sigma factor
FR932_RS03450	COG1595	DNA-templated transcription, initiation
FR932_RS03495	COG1288	antiporter activity
FR932_RS03500	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FR932_RS03530	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FR932_RS03535	COG1447	Phosphotransferase system cellobiose-specific component IIA
FR932_RS03540	COG1486	melibiose metabolic process
FR932_RS03550	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FR932_RS03555	COG0243	molybdopterin cofactor binding
FR932_RS03585	COG1309	transcriptional regulator
FR932_RS03615	COG4176	ABC-type proline glycine betaine transport system permease component
FR932_RS03620	COG4175	Glycine betaine
FR932_RS03620	COG3448	diguanylate cyclase activity
FR932_RS03625	COG3901	Regulator of nitric oxide reductase transcription
FR932_RS03625	COG0348	domain, Protein
FR932_RS03645	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FR932_RS03665	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FR932_RS03685	COG3540	Alkaline phosphatase
FR932_RS03690	COG2813	Specifically methylates the guanine in position
FR932_RS03705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FR932_RS03710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FR932_RS03740	COG2986	histidine ammonia-lyase
FR932_RS03765	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FR932_RS03775	COG1028	Short-chain dehydrogenase reductase Sdr
FR932_RS03780	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FR932_RS03835	COG2801	Transposase and inactivated derivatives
FR932_RS03840	COG2963	transposase activity
FR932_RS03845	COG1247	-acetyltransferase
FR932_RS03850	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FR932_RS03855	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FR932_RS03860	COG0436	Aminotransferase
FR932_RS03880	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FR932_RS03885	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FR932_RS03960	COG0653	protein targeting
FR932_RS03965	COG3279	Response regulator of the LytR AlgR family
FR932_RS03970	COG3275	phosphorelay sensor kinase activity
FR932_RS03975	COG5001	Diguanylate cyclase
FR932_RS03995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FR932_RS04000	COG0745	RESPONSE REGULATOR receiver
FR932_RS04010	COG0667	Aldo Keto reductase
FR932_RS04015	COG2770	Histidine kinase
FR932_RS04015	COG3437	response regulator, receiver
FR932_RS04020	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FR932_RS04025	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FR932_RS04055	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FR932_RS04060	COG0583	DNA-binding transcription factor activity
FR932_RS04065	COG4895	conserved protein (DUF2196)
FR932_RS04070	COG1061	Type III restriction enzyme res subunit
FR932_RS04085	COG1401	restriction endodeoxyribonuclease activity
FR932_RS04140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FR932_RS04145	COG3300	MHYT domain
FR932_RS04145	COG5001	Diguanylate cyclase
FR932_RS04155	COG2199	diguanylate cyclase activity
FR932_RS04200	COG0628	permease
FR932_RS04220	COG0010	Belongs to the arginase family
FR932_RS04225	COG0189	ligase activity
FR932_RS04245	COG2866	Carboxypeptidase
FR932_RS04250	COG1254	Belongs to the acylphosphatase family
FR932_RS04260	COG1846	Transcriptional regulator
FR932_RS04280	COG0745	RESPONSE REGULATOR receiver
FR932_RS04285	COG2205	protein histidine kinase activity
FR932_RS04290	COG4774	siderophore transport
FR932_RS04300	COG0811	peptide transport
FR932_RS04305	COG0811	peptide transport
FR932_RS04310	COG0848	biopolymer transport protein
FR932_RS04400	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FR932_RS04405	COG0363	glucosamine-6-phosphate deaminase activity
FR932_RS04410	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FR932_RS04415	COG0288	reversible hydration of carbon dioxide
FR932_RS04420	COG1278	Cold shock
FR932_RS04435	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FR932_RS04440	COG0303	'Molybdopterin
FR932_RS04445	COG0302	gtp cyclohydrolase
FR932_RS04455	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FR932_RS04460	COG0386	Belongs to the glutathione peroxidase family
FR932_RS04465	COG0326	Molecular chaperone. Has ATPase activity
FR932_RS04470	COG0563	adenylate kinase activity
FR932_RS04485	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FR932_RS04485	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FR932_RS04490	COG3099	Belongs to the UPF0263 family
FR932_RS04495	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FR932_RS04510	COG1609	Transcriptional regulator
FR932_RS04520	COG0477	Major facilitator Superfamily
FR932_RS04525	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FR932_RS04535	COG0156	8-amino-7-oxononanoate synthase activity
FR932_RS04540	COG1063	alcohol dehydrogenase
FR932_RS04555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FR932_RS04560	COG2027	D-alanyl-D-alanine carboxypeptidase
FR932_RS04565	COG2827	Endonuclease containing a URI domain
FR932_RS04580	COG3083	sulfuric ester hydrolase activity
FR932_RS04585	COG3082	Protein of unknown function (DUF1414)
FR932_RS04590	COG3081	Nucleoid-associated protein
FR932_RS04610	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FR932_RS04615	COG0583	DNA-binding transcription factor activity
FR932_RS04620	COG0745	RESPONSE REGULATOR receiver
FR932_RS04630	COG5002	protein histidine kinase activity
FR932_RS04635	COG0745	RESPONSE REGULATOR receiver
FR932_RS04645	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FR932_RS04650	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FR932_RS04680	COG1448	Aminotransferase
FR932_RS04685	COG2223	nitrite transmembrane transporter activity
FR932_RS04695	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FR932_RS04705	COG0517	IMP dehydrogenase activity
FR932_RS04715	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FR932_RS04720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FR932_RS04725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FR932_RS04730	COG1116	anion transmembrane transporter activity
FR932_RS04735	COG0351	phosphomethylpyrimidine kinase
FR932_RS04735	COG0352	thiamine-phosphate diphosphorylase activity
FR932_RS04740	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FR932_RS04750	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FR932_RS04755	COG0372	Belongs to the citrate synthase family
FR932_RS04760	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FR932_RS04790	COG1280	lysine exporter protein (LysE YggA)
FR932_RS04800	COG2226	methyltransferase
FR932_RS04860	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FR932_RS04865	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FR932_RS04870	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FR932_RS04875	COG0539	negative regulation of cytoplasmic translation
FR932_RS04880	COG0776	regulation of translation
FR932_RS04890	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FR932_RS04905	COG3148	PFAM DTW domain containing protein
FR932_RS04910	COG3530	Putative quorum-sensing-regulated virulence factor
FR932_RS04920	COG2916	Histone family protein nucleoid-structuring protein H-NS
FR932_RS04925	COG1757	Na H antiporter
FR932_RS04930	COG1435	thymidine kinase activity
FR932_RS04935	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FR932_RS04980	COG2205	protein histidine kinase activity
FR932_RS04985	COG0745	RESPONSE REGULATOR receiver
FR932_RS05010	COG3123	guanosine phosphorylase activity
FR932_RS05020	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FR932_RS05025	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FR932_RS05035	COG2719	SpoVR family
FR932_RS05040	COG2718	Belongs to the UPF0229 family
FR932_RS05045	COG2766	serine protein kinase
FR932_RS05055	COG0066	3-isopropylmalate dehydratase activity
FR932_RS05060	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FR932_RS05065	COG4109	DRTGG domain
FR932_RS05070	COG2271	Major facilitator Superfamily
FR932_RS05075	COG1643	Atp-dependent helicase
FR932_RS05080	COG5001	Diguanylate cyclase
FR932_RS05080	COG4251	negative regulation of phosphorylation
FR932_RS05080	COG2203	Gaf domain
FR932_RS05080	COG3706	GGDEF domain
FR932_RS05105	COG2233	PERMEase
FR932_RS05115	COG0390	transport system, permease component
FR932_RS05180	COG1012	belongs to the aldehyde dehydrogenase family
FR932_RS05185	COG2165	general secretion pathway protein
FR932_RS05195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR932_RS05200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FR932_RS05250	COG0583	DNA-binding transcription factor activity
FR932_RS05270	COG0583	DNA-binding transcription factor activity
FR932_RS05275	COG3038	cytochrome b561
FR932_RS05280	COG2353	YceI-like domain
FR932_RS05285	COG3706	GGDEF domain
FR932_RS05300	COG2091	lysine biosynthetic process via aminoadipic acid
FR932_RS05315	COG4720	Psort location CytoplasmicMembrane, score
FR932_RS05320	COG0673	inositol 2-dehydrogenase activity
FR932_RS05325	COG2239	Acts as a magnesium transporter
FR932_RS05345	COG0840	transmembrane signaling receptor activity
FR932_RS05385	COG0791	NLP P60 protein
FR932_RS05390	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FR932_RS05400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FR932_RS05425	COG0437	4 iron, 4 sulfur cluster binding
FR932_RS05430	COG3301	Polysulphide reductase, NrfD
FR932_RS05435	COG1138	Cytochrome C-type biogenesis protein
FR932_RS05440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FR932_RS05445	COG4235	cytochrome complex assembly
FR932_RS05445	COG3088	subunit of a heme lyase
FR932_RS05455	COG3568	Endonuclease Exonuclease Phosphatase
FR932_RS05465	COG2274	protein secretion by the type I secretion system
FR932_RS05505	COG4335	DNA alkylation repair
FR932_RS05510	COG2824	Alkylphosphonate utilization operon protein PhnA
FR932_RS05515	COG0076	glutamate decarboxylase activity
FR932_RS05525	COG0019	diaminopimelate decarboxylase activity
FR932_RS05570	COG0295	cytidine deaminase activity
FR932_RS05575	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FR932_RS05580	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FR932_RS05580	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FR932_RS05585	COG0489	protein tyrosine kinase activity
FR932_RS05590	COG0572	uridine kinase
FR932_RS05595	COG0717	Belongs to the dCTP deaminase family
FR932_RS05600	COG3314	Sporulation integral membrane protein YlbJ
FR932_RS05610	COG2925	Exonuclease
FR932_RS05615	COG2258	MOSC domain
FR932_RS05625	COG3148	PFAM DTW domain containing protein
FR932_RS05630	COG0673	inositol 2-dehydrogenase activity
FR932_RS05645	COG1846	Transcriptional regulator
FR932_RS05650	COG2814	Major facilitator Superfamily
FR932_RS05660	COG2314	TM2 domain
FR932_RS05680	COG2165	general secretion pathway protein
FR932_RS05685	COG0737	Belongs to the 5'-nucleotidase family
FR932_RS05690	COG2226	methyltransferase
FR932_RS05705	COG1027	Aspartate ammonia-lyase
FR932_RS05710	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FR932_RS05715	COG0297	glycogen (starch) synthase activity
FR932_RS05720	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FR932_RS05725	COG0058	SHG alpha-glucan phosphorylase activity
FR932_RS05730	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FR932_RS05740	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FR932_RS05745	COG3437	response regulator, receiver
FR932_RS05750	COG3437	response regulator, receiver
FR932_RS05755	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FR932_RS05760	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FR932_RS05785	COG0513	Belongs to the DEAD box helicase family
FR932_RS05800	COG3106	COG3106 Predicted ATPase
FR932_RS05805	COG3768	UPF0283 membrane protein
FR932_RS05815	COG1566	PFAM secretion protein HlyD family protein
FR932_RS05840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FR932_RS05845	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FR932_RS05850	COG2375	cellular response to nickel ion
FR932_RS05885	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FR932_RS05895	COG0501	Belongs to the peptidase M48B family
FR932_RS05900	COG3273	potassium ion transport
FR932_RS05900	COG0471	metal ion transport
FR932_RS05955	COG3604	Transcriptional regulator
FR932_RS05960	COG0534	Mate efflux family protein
FR932_RS05965	COG0307	riboflavin synthase, alpha
FR932_RS05975	COG1346	cytolysis
FR932_RS05980	COG1380	Effector of murein hydrolase LrgA
FR932_RS05985	COG0602	queuosine metabolic process
FR932_RS06015	COG1763	Mo-molybdopterin cofactor biosynthetic process
FR932_RS06020	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FR932_RS06025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR932_RS06030	COG1061	Type III restriction enzyme res subunit
FR932_RS06035	COG0753	catalase activity
FR932_RS06040	COG0753	catalase activity
FR932_RS06050	COG0183	Belongs to the thiolase family
FR932_RS06055	COG1024	Enoyl-CoA hydratase
FR932_RS06055	COG1250	3-hydroxyacyl-CoA dehydrogenase
FR932_RS06075	COG0583	DNA-binding transcription factor activity
FR932_RS06095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FR932_RS06100	COG3069	C4-dicarboxylate transmembrane transporter activity
FR932_RS06105	COG0521	Mo-molybdopterin cofactor biosynthetic process
FR932_RS06115	COG1032	radical SAM domain protein
FR932_RS06125	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FR932_RS06130	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FR932_RS06135	COG1216	Glycosyl transferase, family 2
FR932_RS06160	COG0438	transferase activity, transferring glycosyl groups
FR932_RS06175	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FR932_RS06185	COG4591	ABC-type transport system involved in lipoprotein release permease component
FR932_RS06190	COG1136	(ABC) transporter
FR932_RS06195	COG4591	ABC-type transport system involved in lipoprotein release permease component
FR932_RS06230	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FR932_RS06240	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FR932_RS06250	COG5001	Diguanylate cyclase
FR932_RS06250	COG5002	protein histidine kinase activity
FR932_RS06255	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FR932_RS06260	COG0072	phenylalanine-tRNA ligase activity
FR932_RS06265	COG0776	regulation of translation
FR932_RS06270	COG0659	secondary active sulfate transmembrane transporter activity
FR932_RS06275	COG1530	ribonuclease E activity
FR932_RS06280	COG0564	pseudouridine synthase activity
FR932_RS06285	COG0424	maF-like protein
FR932_RS06290	COG1399	metal-binding, possibly nucleic acid-binding protein
FR932_RS06305	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FR932_RS06310	COG1028	Short-chain dehydrogenase reductase Sdr
FR932_RS06320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FR932_RS06325	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FR932_RS06335	COG0470	DNA polymerase III
FR932_RS06340	COG0084	hydrolase, TatD family'
FR932_RS06355	COG0658	competence protein
FR932_RS06355	COG2333	competence protein COMEC
FR932_RS06365	COG1090	epimerase
FR932_RS06375	COG0463	Glycosyl transferase, family 2
FR932_RS06380	COG0745	RESPONSE REGULATOR receiver
FR932_RS06385	COG2205	protein histidine kinase activity
FR932_RS06400	COG1671	Belongs to the UPF0178 family
FR932_RS06405	COG2989	Protein conserved in bacteria
FR932_RS06410	COG3108	Peptidase M15
FR932_RS06425	COG2244	polysaccharide biosynthetic process
FR932_RS06455	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FR932_RS06460	COG4988	ABC transporter
FR932_RS06470	COG1294	oxidase, subunit
FR932_RS06500	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FR932_RS06505	COG0131	Imidazoleglycerol-phosphate dehydratase
FR932_RS06505	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FR932_RS06510	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FR932_RS06515	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FR932_RS06520	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FR932_RS06530	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FR932_RS06535	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FR932_RS06540	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FR932_RS06545	COG1199	ATP-dependent helicase activity
FR932_RS06550	COG1214	PFAM Peptidase M22, glycoprotease
FR932_RS06555	COG0596	Alpha beta hydrolase
FR932_RS06560	COG0318	PFAM AMP-dependent synthetase and ligase
FR932_RS06565	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FR932_RS06570	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FR932_RS06575	COG2894	cell division
FR932_RS06585	COG3100	YcgL domain-containing protein
FR932_RS06590	COG2951	lytic endotransglycosylase activity
FR932_RS06595	COG0179	Fumarylacetoacetate (FAA) hydrolase
FR932_RS06600	COG2983	Belongs to the UPF0260 family
FR932_RS06610	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FR932_RS06625	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FR932_RS06630	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FR932_RS06635	COG1177	transmembrane transport
FR932_RS06655	COG0037	tRNA processing
FR932_RS06660	COG0589	response to stress
FR932_RS06690	COG2010	Cytochrome c
FR932_RS06705	COG3278	Belongs to the heme-copper respiratory oxidase family
FR932_RS06710	COG0033	Phosphoglucomutase
FR932_RS06720	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FR932_RS06745	COG2203	Gaf domain
FR932_RS06745	COG2199	diguanylate cyclase activity
FR932_RS06755	COG0443	Heat shock 70 kDa protein
FR932_RS06765	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FR932_RS06765	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FR932_RS06770	COG3008	intermembrane lipid transfer
FR932_RS06775	COG2995	paraquat-inducible protein a
FR932_RS06780	COG2995	paraquat-inducible protein a
FR932_RS06785	COG3141	response to X-ray
FR932_RS06790	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
FR932_RS06795	COG0793	Belongs to the peptidase S41A family
FR932_RS06800	COG0308	aminopeptidase N
FR932_RS06805	COG2902	Dehydrogenase
FR932_RS06820	COG0116	Belongs to the methyltransferase superfamily
FR932_RS06820	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FR932_RS06830	COG0488	(ABC) transporter
FR932_RS06845	COG4974	Belongs to the 'phage' integrase family
FR932_RS06850	COG0827	DNA restriction-modification system
FR932_RS06855	COG2205	protein histidine kinase activity
FR932_RS06855	COG0784	Response regulator, receiver
FR932_RS06935	COG4695	Portal protein
FR932_RS07055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FR932_RS07060	COG1067	ATP-dependent peptidase activity
FR932_RS07065	COG3122	Protein conserved in bacteria
FR932_RS07080	COG1376	ErfK ybiS ycfS ynhG family protein
FR932_RS07095	COG2203	Gaf domain
FR932_RS07095	COG3706	GGDEF domain
FR932_RS07095	COG4251	negative regulation of phosphorylation
FR932_RS07095	COG5001	Diguanylate cyclase
FR932_RS07100	COG2968	Membrane
FR932_RS07115	COG3781	membrane
FR932_RS07140	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FR932_RS07150	COG1115	amino acid carrier protein
FR932_RS07165	COG4977	sequence-specific DNA binding
FR932_RS07165	COG1917	Cupin 2, conserved barrel domain protein
FR932_RS07180	COG3220	belongs to the UPF0276 family
FR932_RS07220	COG0513	Belongs to the DEAD box helicase family
FR932_RS07235	COG0583	DNA-binding transcription factor activity
FR932_RS07275	COG0500	methyltransferase
FR932_RS07300	COG2010	Cytochrome c
FR932_RS07310	COG3278	Belongs to the heme-copper respiratory oxidase family
FR932_RS07355	COG2070	2-Nitropropane dioxygenase
FR932_RS07355	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FR932_RS07370	COG0300	oxidoreductase activity
FR932_RS07370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FR932_RS07370	COG3321	synthase
FR932_RS07370	COG4221	oxidoreductase activity
FR932_RS07380	COG4628	conserved protein (DUF2132)
FR932_RS07385	COG1752	Esterase of the alpha-beta hydrolase superfamily
FR932_RS07390	COG0469	pyruvate kinase activity
FR932_RS07400	COG0367	asparagine synthase
FR932_RS07405	COG0183	Belongs to the thiolase family
FR932_RS07420	COG2030	dehydratase
FR932_RS07425	COG0318	PFAM AMP-dependent synthetase and ligase
FR932_RS07435	COG3323	Protein of unknown function (DUF1653)
FR932_RS07435	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FR932_RS07440	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FR932_RS07465	COG1187	pseudouridine synthase activity
FR932_RS07470	COG2996	Protein conserved in bacteria
FR932_RS07480	COG0542	response to heat
FR932_RS07490	COG1278	Cold shock
FR932_RS07495	COG2911	Protein conserved in bacteria
FR932_RS07500	COG0729	surface antigen
FR932_RS07510	COG0513	Belongs to the DEAD box helicase family
FR932_RS07515	COG0583	DNA-binding transcription factor activity
FR932_RS07520	COG0189	ligase activity
FR932_RS07530	COG0314	molybdopterin synthase activity
FR932_RS07535	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FR932_RS07540	COG0315	cyclic pyranopterin monophosphate synthase activity
FR932_RS07545	COG0521	Mo-molybdopterin cofactor biosynthetic process
FR932_RS07560	COG3005	denitrification pathway
FR932_RS07570	COG0243	molybdopterin cofactor binding
FR932_RS07580	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FR932_RS07585	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FR932_RS07590	COG3850	Histidine kinase
FR932_RS07595	COG2197	response regulator
FR932_RS07605	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FR932_RS07640	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FR932_RS07645	COG0045	succinate-CoA ligase (ADP-forming) activity
FR932_RS07650	COG0508	dehydrogenase complex catalyzes the overall conversion of
FR932_RS07655	COG0567	Dehydrogenase, E1 component
FR932_RS07660	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FR932_RS07665	COG1053	succinate dehydrogenase
FR932_RS07670	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FR932_RS07685	COG2205	protein histidine kinase activity
FR932_RS07700	COG2176	DNA-directed DNA polymerase activity
FR932_RS07715	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FR932_RS07720	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FR932_RS07725	COG2835	tetraacyldisaccharide 4'-kinase activity
FR932_RS07730	COG1663	tetraacyldisaccharide 4'-kinase activity
FR932_RS07735	COG1132	(ABC) transporter
FR932_RS07770	COG0156	8-amino-7-oxononanoate synthase activity
FR932_RS07775	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FR932_RS07780	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FR932_RS07790	COG0017	Asparaginyl-tRNA synthetase
FR932_RS07795	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FR932_RS07820	COG0778	Nitroreductase
FR932_RS07825	COG1902	pentaerythritol trinitrate reductase activity
FR932_RS07825	COG0446	pyridine nucleotide-disulphide oxidoreductase
FR932_RS07830	COG0616	signal peptide processing
FR932_RS07835	COG0252	asparaginase activity
FR932_RS07840	COG2814	Major facilitator Superfamily
FR932_RS07845	COG0583	DNA-binding transcription factor activity
FR932_RS07860	COG2195	Cleaves the N-terminal amino acid of tripeptides
FR932_RS07870	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FR932_RS07875	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FR932_RS07885	COG0583	DNA-binding transcription factor activity
FR932_RS07890	COG0318	PFAM AMP-dependent synthetase and ligase
FR932_RS07930	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FR932_RS07945	COG0384	phenazine biosynthesis protein PhzF
FR932_RS07990	COG0513	Belongs to the DEAD box helicase family
FR932_RS08005	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FR932_RS08030	COG1028	Short-chain dehydrogenase reductase Sdr
FR932_RS08060	COG0300	oxidoreductase activity
FR932_RS08065	COG1309	transcriptional regulator
FR932_RS08080	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FR932_RS08090	COG1454	alcohol dehydrogenase
FR932_RS08140	COG0561	phosphatase activity
FR932_RS08150	COG0242	peptide deformylase activity
FR932_RS08160	COG2169	Transcriptional regulator
FR932_RS08160	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FR932_RS08215	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FR932_RS08230	COG2267	carboxylic ester hydrolase activity
FR932_RS08240	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FR932_RS08260	COG1918	ferrous iron import across plasma membrane
FR932_RS08265	COG1132	(ABC) transporter
FR932_RS08270	COG0814	amino acid
FR932_RS08290	COG2165	general secretion pathway protein
FR932_RS08300	COG1451	nucleotide metabolic process
FR932_RS08320	COG2165	general secretion pathway protein
FR932_RS08335	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FR932_RS08340	COG1703	isobutyryl-CoA mutase activity
FR932_RS08340	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FR932_RS08340	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FR932_RS08355	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FR932_RS08365	COG0733	neurotransmitter:sodium symporter activity
FR932_RS08390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FR932_RS08410	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FR932_RS08415	COG1960	acyl-CoA dehydrogenase activity
FR932_RS08420	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FR932_RS08425	COG1024	Enoyl-CoA hydratase
FR932_RS08430	COG4770	biotin carboxylase activity
FR932_RS08440	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FR932_RS08455	COG0640	Transcriptional regulator
FR932_RS08460	COG0753	catalase activity
FR932_RS08465	COG4667	esterase of the alpha-beta hydrolase superfamily
FR932_RS08470	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FR932_RS08490	COG1573	uracil-dna glycosylase
FR932_RS08500	COG3257	ureidoglycine aminohydrolase activity
FR932_RS08505	COG1742	UPF0060 membrane protein
FR932_RS08510	COG0519	Catalyzes the synthesis of GMP from XMP
FR932_RS08540	COG1278	Cold shock
FR932_RS08545	COG0646	methionine synthase
FR932_RS08545	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FR932_RS08555	COG0784	Response regulator, receiver
FR932_RS08555	COG2205	protein histidine kinase activity
FR932_RS08560	COG2207	Transcriptional regulator
FR932_RS08565	COG1979	alcohol dehydrogenase
FR932_RS08575	COG1280	lysine exporter protein (LysE YggA)
FR932_RS08600	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FR932_RS08605	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FR932_RS08610	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FR932_RS08620	COG3706	GGDEF domain
FR932_RS08625	COG0471	metal ion transport
FR932_RS08630	COG3706	GGDEF domain
FR932_RS08645	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FR932_RS08670	COG0546	phosphoglycolate phosphatase activity
FR932_RS08710	COG3791	Glutathione-dependent formaldehyde-activating
FR932_RS08735	COG2161	toxin-antitoxin pair type II binding
FR932_RS08740	COG4115	mRNA cleavage
FR932_RS08770	COG3813	Protein conserved in bacteria
FR932_RS08790	COG1942	4-Oxalocrotonate Tautomerase
FR932_RS08805	COG0698	ribose 5-phosphate isomerase
FR932_RS08880	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FR932_RS08885	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FR932_RS08895	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FR932_RS08945	COG0730	response to heat
FR932_RS08985	COG1054	Belongs to the UPF0176 family
FR932_RS08990	COG0584	glycerophosphoryl diester phosphodiesterase
FR932_RS08995	COG2271	Major facilitator Superfamily
FR932_RS09015	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
FR932_RS09025	COG1024	Enoyl-CoA hydratase
FR932_RS09030	COG0583	DNA-binding transcription factor activity
FR932_RS09060	COG2203	Gaf domain
FR932_RS09060	COG5001	Diguanylate cyclase
FR932_RS09060	COG3706	GGDEF domain
FR932_RS09060	COG4251	negative regulation of phosphorylation
FR932_RS09090	COG1088	dTDP-glucose 4,6-dehydratase activity
FR932_RS09105	COG0438	transferase activity, transferring glycosyl groups
FR932_RS09110	COG0826	peptidase U32
FR932_RS09140	COG0583	DNA-binding transcription factor activity
FR932_RS09155	COG2814	Major facilitator Superfamily
FR932_RS09175	COG1136	(ABC) transporter
FR932_RS09180	COG0513	Belongs to the DEAD box helicase family
FR932_RS09200	COG1477	protein flavinylation
FR932_RS09215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FR932_RS09265	COG4964	Belongs to the GSP D family
FR932_RS09335	COG1151	hydroxylamine reductase activity
FR932_RS09340	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FR932_RS09345	COG0589	response to stress
FR932_RS09360	COG0745	RESPONSE REGULATOR receiver
FR932_RS09360	COG2205	protein histidine kinase activity
FR932_RS09360	COG3292	Two component regulator propeller
FR932_RS09370	COG0668	transmembrane transport
FR932_RS09380	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
FR932_RS09385	COG2944	sequence-specific DNA binding
FR932_RS09415	COG1228	amidohydrolase
FR932_RS09420	COG0010	Belongs to the arginase family
FR932_RS09425	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FR932_RS09430	COG2986	histidine ammonia-lyase
FR932_RS09445	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FR932_RS09455	COG3615	Tellurite resistance protein tehB
FR932_RS09460	COG2723	6-phospho-beta-galactosidase activity
FR932_RS09475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FR932_RS09480	COG2137	regulation of response to DNA damage stimulus
FR932_RS09485	COG0653	protein targeting
FR932_RS09500	COG0840	transmembrane signaling receptor activity
FR932_RS09505	COG0625	glutathione transferase activity
FR932_RS09515	COG0765	amino acid transport
FR932_RS09535	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FR932_RS09550	COG0625	glutathione transferase activity
FR932_RS09555	COG0583	DNA-binding transcription factor activity
FR932_RS09565	COG0583	DNA-binding transcription factor activity
FR932_RS09570	COG0435	Glutathione S-transferase
FR932_RS09575	COG1741	Belongs to the pirin family
FR932_RS09585	COG4533	DNA binding
FR932_RS09625	COG2205	protein histidine kinase activity
FR932_RS09625	COG0784	Response regulator, receiver
FR932_RS09625	COG2198	Histidine kinase
FR932_RS09630	COG1879	ABC-type sugar transport system periplasmic component
FR932_RS09635	COG0745	RESPONSE REGULATOR receiver
FR932_RS09660	COG0300	oxidoreductase activity
FR932_RS09665	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FR932_RS09675	COG5001	Diguanylate cyclase
FR932_RS09680	COG1280	lysine exporter protein (LysE YggA)
FR932_RS09685	COG0668	transmembrane transport
FR932_RS09715	COG2130	NADP-dependent
FR932_RS09725	COG0625	glutathione transferase activity
FR932_RS09730	COG0583	DNA-binding transcription factor activity
FR932_RS09740	COG1716	ATPase activity
FR932_RS09740	COG5001	Diguanylate cyclase
FR932_RS09750	COG1441	menaquinone biosynthetic process
FR932_RS09755	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FR932_RS09765	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FR932_RS09770	COG1169	isochorismate synthase
FR932_RS09775	COG0730	response to heat
FR932_RS09805	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FR932_RS09815	COG0205	6-phosphofructokinase activity
FR932_RS09820	COG0556	nucleotide-excision repair
FR932_RS09880	COG5001	Diguanylate cyclase
FR932_RS09880	COG3300	MHYT domain
FR932_RS09885	COG4657	Part of a membrane complex involved in electron transport
FR932_RS09890	COG2878	Part of a membrane complex involved in electron transport
FR932_RS09895	COG4656	Part of a membrane complex involved in electron transport
FR932_RS09900	COG4658	electron transport chain
FR932_RS09910	COG4660	Part of a membrane complex involved in electron transport
FR932_RS09915	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FR932_RS09970	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FR932_RS09975	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FR932_RS10060	COG1477	protein flavinylation
FR932_RS10065	COG1584	GPR1 FUN34 yaaH family protein
FR932_RS10075	COG2885	chlorophyll binding
FR932_RS10090	COG2056	Na+-H+ antiporter family
FR932_RS10095	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FR932_RS10105	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FR932_RS10110	COG0484	heat shock protein binding
FR932_RS10135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FR932_RS10145	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FR932_RS10155	COG3437	response regulator, receiver
FR932_RS10170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FR932_RS10180	COG1012	belongs to the aldehyde dehydrogenase family
FR932_RS10190	COG0583	DNA-binding transcription factor activity
FR932_RS10240	COG2197	response regulator
FR932_RS10245	COG0204	Acyl-transferase
FR932_RS10265	COG4565	transcriptional regulatory protein
FR932_RS10270	COG3290	protein histidine kinase activity
FR932_RS10275	COG0840	transmembrane signaling receptor activity
FR932_RS10280	COG0583	DNA-binding transcription factor activity
FR932_RS10305	COG0583	DNA-binding transcription factor activity
FR932_RS10310	COG1942	4-Oxalocrotonate Tautomerase
FR932_RS10340	COG0475	glutathione-regulated potassium exporter activity
FR932_RS10340	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FR932_RS10345	COG0640	Transcriptional regulator
FR932_RS10350	COG0798	PFAM Bile acid sodium symporter
FR932_RS10355	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FR932_RS10375	COG4134	Bacterial extracellular solute-binding protein
FR932_RS10380	COG4135	transport system, permease component
FR932_RS10385	COG4136	ATPase activity
FR932_RS10390	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FR932_RS10395	COG5002	protein histidine kinase activity
FR932_RS10395	COG2198	Histidine kinase
FR932_RS10395	COG0784	Response regulator, receiver
FR932_RS10405	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FR932_RS10405	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FR932_RS10410	COG1560	Kdo2-lipid A biosynthetic process
FR932_RS10435	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FR932_RS10440	COG1823	symporter activity
FR932_RS10445	COG5001	Diguanylate cyclase
FR932_RS10445	COG1716	ATPase activity
FR932_RS10460	COG3585	molybdate ion transport
FR932_RS10460	COG2005	Transcriptional regulator
FR932_RS10465	COG3681	Belongs to the UPF0597 family
FR932_RS10470	COG3706	GGDEF domain
FR932_RS10475	COG3706	GGDEF domain
FR932_RS10480	COG0725	ABC transporter, periplasmic molybdate-binding protein
FR932_RS10485	COG4149	molybdate abc transporter
FR932_RS10535	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FR932_RS10540	COG0534	Mate efflux family protein
FR932_RS10545	COG0583	DNA-binding transcription factor activity
FR932_RS10550	COG4172	Belongs to the ABC transporter superfamily
FR932_RS10555	COG0747	negative chemotaxis
FR932_RS10560	COG0601	transmembrane transport
FR932_RS10565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FR932_RS10570	COG3104	oligopeptide transport
FR932_RS10575	COG2165	general secretion pathway protein
FR932_RS10600	COG0786	glutamate:sodium symporter activity
FR932_RS10610	COG2204	response regulator
FR932_RS10620	COG0438	transferase activity, transferring glycosyl groups
FR932_RS10630	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FR932_RS10635	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FR932_RS10640	COG1121	(ABC) transporter
FR932_RS10665	COG2814	Major facilitator Superfamily
FR932_RS10685	COG2205	protein histidine kinase activity
FR932_RS10690	COG0745	RESPONSE REGULATOR receiver
FR932_RS10700	COG1199	ATP-dependent helicase activity
FR932_RS10705	COG0730	response to heat
FR932_RS10720	COG0210	DNA helicase
FR932_RS10730	COG2194	sulfuric ester hydrolase activity
FR932_RS10740	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FR932_RS10760	COG0840	transmembrane signaling receptor activity
FR932_RS10760	COG0840	transmembrane signaling receptor activity
FR932_RS10775	COG4232	protein-disulfide reductase activity
FR932_RS10795	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
FR932_RS10830	COG0714	Associated with various cellular activities
FR932_RS10835	COG3119	arylsulfatase activity
FR932_RS10845	COG4607	ABC-type enterochelin transport system periplasmic component
FR932_RS10850	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FR932_RS10855	COG4605	iron ion homeostasis
FR932_RS10860	COG4604	ABC transporter, ATP-binding protein
FR932_RS10880	COG3706	GGDEF domain
FR932_RS10910	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FR932_RS10915	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FR932_RS10920	COG1757	Na H antiporter
FR932_RS10925	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FR932_RS10940	COG0641	radical SAM
FR932_RS10945	COG3119	arylsulfatase activity
FR932_RS10955	COG1051	belongs to the nudix hydrolase family
FR932_RS10990	COG0419	ATPase involved in DNA repair
FR932_RS10995	COG0420	3'-5' exonuclease activity
FR932_RS11035	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FR932_RS11040	COG0814	amino acid
FR932_RS11050	COG1280	lysine exporter protein (LysE YggA)
FR932_RS11055	COG0454	-acetyltransferase
FR932_RS11070	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FR932_RS11100	COG1328	CTP reductase activity
FR932_RS11105	COG0602	queuosine metabolic process
FR932_RS11110	COG4221	oxidoreductase activity
FR932_RS11115	COG3706	GGDEF domain
FR932_RS11135	COG1024	Enoyl-CoA hydratase
FR932_RS11135	COG1250	3-hydroxyacyl-CoA dehydrogenase
FR932_RS11140	COG0183	Belongs to the thiolase family
FR932_RS11145	COG0714	Associated with various cellular activities
FR932_RS11175	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FR932_RS11180	COG2067	long-chain fatty acid transport protein
FR932_RS11190	COG2067	long-chain fatty acid transport protein
FR932_RS11195	COG0406	alpha-ribazole phosphatase activity
FR932_RS11200	COG0438	transferase activity, transferring glycosyl groups
FR932_RS11220	COG0668	transmembrane transport
FR932_RS11235	COG0616	signal peptide processing
FR932_RS11240	COG1028	Short-chain dehydrogenase reductase Sdr
FR932_RS11250	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FR932_RS11255	COG1984	allophanate hydrolase subunit 2
FR932_RS11280	COG3706	GGDEF domain
FR932_RS11290	COG4807	Protein conserved in bacteria
FR932_RS11310	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FR932_RS11315	COG0443	Heat shock 70 kDa protein
FR932_RS11325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FR932_RS11330	COG2207	Transcriptional regulator
FR932_RS11345	COG0004	ammonium transporteR
FR932_RS11350	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FR932_RS11355	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FR932_RS11360	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FR932_RS11365	COG1053	succinate dehydrogenase
FR932_RS11375	COG0700	Nucleoside recognition
FR932_RS11380	COG3366	ferrous iron transmembrane transporter activity
FR932_RS11390	COG1764	response to oxidative stress
FR932_RS11435	COG1575	Belongs to the MenA family. Type 1 subfamily
FR932_RS11440	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FR932_RS11445	COG1301	dicarboxylic acid transport
FR932_RS11450	COG2252	PERMEase
FR932_RS11470	COG4266	Belongs to the allantoicase family
FR932_RS11485	COG0671	phosphoesterase, PA-phosphatase related
FR932_RS11500	COG0583	DNA-binding transcription factor activity
FR932_RS11510	COG1309	transcriptional regulator
FR932_RS11515	COG1215	transferase activity, transferring glycosyl groups
FR932_RS11520	COG0438	transferase activity, transferring glycosyl groups
FR932_RS11525	COG0402	S-adenosylhomocysteine deaminase activity
FR932_RS11540	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FR932_RS11590	COG2165	general secretion pathway protein
FR932_RS11595	COG2197	response regulator
FR932_RS11600	COG0708	Exodeoxyribonuclease III
FR932_RS11605	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FR932_RS11615	COG4215	(ABC) transporter
FR932_RS11620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FR932_RS11630	COG2116	formate transmembrane transporter activity
FR932_RS11635	COG1882	Formate acetyltransferase
FR932_RS11640	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FR932_RS11645	COG2226	methyltransferase
FR932_RS11650	COG3092	negative regulation of chromosome organization
FR932_RS11655	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FR932_RS11660	COG0280	phosphate acetyltransferase
FR932_RS11660	COG0857	belongs to the CobB CobQ family
FR932_RS11670	COG0628	permease
FR932_RS11680	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FR932_RS11685	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FR932_RS11690	COG3115	cell septum assembly
FR932_RS11695	COG1196	nuclear chromosome segregation
FR932_RS11710	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FR932_RS11715	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR932_RS11725	COG2190	(PTS) system
FR932_RS11730	COG3706	GGDEF domain
FR932_RS11735	COG0840	transmembrane signaling receptor activity
FR932_RS11740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FR932_RS11765	COG1187	pseudouridine synthase activity
FR932_RS11775	COG0431	NADPH-dependent FMN reductase
FR932_RS11785	COG3300	MHYT domain
FR932_RS11785	COG5001	Diguanylate cyclase
FR932_RS11795	COG0786	glutamate:sodium symporter activity
FR932_RS11810	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
FR932_RS11815	COG0579	oxidoreductase
FR932_RS11835	COG1393	Belongs to the ArsC family
FR932_RS11840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FR932_RS11855	COG1309	transcriptional regulator
FR932_RS11865	COG0516	GMP reductase activity
FR932_RS11870	COG1605	Chorismate mutase
FR932_RS11880	COG1595	DNA-templated transcription, initiation
FR932_RS11895	COG2199	diguanylate cyclase activity
FR932_RS11910	COG2165	general secretion pathway protein
FR932_RS11920	COG0346	lactoylglutathione lyase activity
FR932_RS11925	COG4533	DNA binding
FR932_RS11940	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FR932_RS11955	COG1560	Kdo2-lipid A biosynthetic process
FR932_RS11960	COG0589	response to stress
FR932_RS11965	COG0659	secondary active sulfate transmembrane transporter activity
FR932_RS11970	COG3383	formate dehydrogenase (NAD+) activity
FR932_RS11975	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FR932_RS11990	COG2233	PERMEase
FR932_RS11995	COG1902	pentaerythritol trinitrate reductase activity
FR932_RS12010	COG3655	Transcriptional regulator
FR932_RS12045	COG4251	negative regulation of phosphorylation
FR932_RS12045	COG5001	Diguanylate cyclase
FR932_RS12045	COG3706	GGDEF domain
FR932_RS12045	COG2203	Gaf domain
FR932_RS12060	COG2252	PERMEase
FR932_RS12070	COG4968	Prepilin-type N-terminal cleavage methylation domain
FR932_RS12090	COG0641	radical SAM
FR932_RS12095	COG3119	arylsulfatase activity
FR932_RS12100	COG2197	response regulator
FR932_RS12125	COG4771	TonB-dependent receptor
FR932_RS12150	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FR932_RS12155	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FR932_RS12160	COG1132	(ABC) transporter
FR932_RS12165	COG3102	Protein conserved in bacteria
FR932_RS12170	COG2926	Belongs to the UPF0265 family
FR932_RS12180	COG3408	Glycogen debranching enzyme
FR932_RS12180	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FR932_RS12225	COG2801	Transposase and inactivated derivatives
FR932_RS12230	COG2963	transposase activity
FR932_RS12235	COG0488	(ABC) transporter
FR932_RS12245	COG0583	DNA-binding transcription factor activity
FR932_RS12250	COG1556	Lactate utilization protein
FR932_RS12255	COG1139	Iron-sulfur cluster binding protein
FR932_RS12260	COG0247	lactate metabolic process
FR932_RS12265	COG1620	l-lactate permease
FR932_RS12285	COG5001	Diguanylate cyclase
FR932_RS12310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FR932_RS12315	COG1396	sequence-specific DNA binding
FR932_RS12320	COG3135	benzoate transporter
FR932_RS12325	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FR932_RS12335	COG0514	ATP-dependent DNA helicase (RecQ)
FR932_RS12345	COG1263	PTS System
FR932_RS12345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FR932_RS12345	COG2190	(PTS) system
FR932_RS12350	COG0363	glucosamine-6-phosphate deaminase activity
FR932_RS12355	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FR932_RS12365	COG0023	Translation Initiation Factor
FR932_RS12375	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FR932_RS12385	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FR932_RS12390	COG4181	ATPase activity
FR932_RS12400	COG0417	DNA replication proofreading
FR932_RS12430	COG1358	cellular component organization or biogenesis
FR932_RS12455	COG0668	transmembrane transport
FR932_RS12470	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FR932_RS12480	COG0009	L-threonylcarbamoyladenylate synthase
FR932_RS12490	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FR932_RS12495	COG0512	Glutamine amidotransferase of anthranilate synthase
FR932_RS12495	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FR932_RS12500	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FR932_RS12505	COG0135	phosphoribosylanthranilate isomerase activity
FR932_RS12505	COG0134	indole-3-glycerol-phosphate synthase activity
FR932_RS12510	COG0133	tryptophan synthase activity
FR932_RS12515	COG0159	tryptophan synthase activity
FR932_RS12525	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FR932_RS12535	COG0733	neurotransmitter:sodium symporter activity
FR932_RS12545	COG0814	amino acid
FR932_RS12550	COG1609	Transcriptional regulator
FR932_RS12555	COG0784	Response regulator, receiver
FR932_RS12555	COG5002	protein histidine kinase activity
FR932_RS12555	COG2205	protein histidine kinase activity
FR932_RS12560	COG2017	converts alpha-aldose to the beta-anomer
FR932_RS12565	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FR932_RS12570	COG1085	galactose-1-phosphate uridylyltransferase
FR932_RS12575	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FR932_RS12580	COG1609	Transcriptional regulator
FR932_RS12585	COG3250	beta-galactosidase activity
FR932_RS12590	COG2731	YhcH YjgK YiaL family protein
FR932_RS12595	COG0531	amino acid
FR932_RS12600	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FR932_RS12605	COG2890	protein-(glutamine-N5) methyltransferase activity
FR932_RS12610	COG2840	Smr protein MutS2
FR932_RS12625	COG2062	phosphohistidine phosphatase, SixA
FR932_RS12630	COG1025	Belongs to the peptidase M16 family
FR932_RS12635	COG1280	lysine exporter protein (LysE YggA)
FR932_RS12645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FR932_RS12645	COG1042	CoA-binding domain protein
FR932_RS12645	COG0045	succinate-CoA ligase (ADP-forming) activity
FR932_RS12700	COG5001	Diguanylate cyclase
FR932_RS12700	COG5002	protein histidine kinase activity
FR932_RS12705	COG2205	protein histidine kinase activity
FR932_RS12710	COG0745	RESPONSE REGULATOR receiver
FR932_RS12740	COG0300	oxidoreductase activity
FR932_RS12750	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FR932_RS12760	COG0415	Belongs to the DNA photolyase family
FR932_RS12765	COG1012	belongs to the aldehyde dehydrogenase family
FR932_RS12770	COG3710	Transcriptional regulator
FR932_RS12775	COG1024	Enoyl-CoA hydratase
FR932_RS12775	COG1250	3-hydroxyacyl-CoA dehydrogenase
FR932_RS12850	COG1280	lysine exporter protein (LysE YggA)
FR932_RS12860	COG5002	protein histidine kinase activity
FR932_RS12860	COG5001	Diguanylate cyclase
FR932_RS12865	COG0814	amino acid
FR932_RS12875	COG1011	Hydrolase
FR932_RS12880	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FR932_RS12890	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FR932_RS12905	COG1253	flavin adenine dinucleotide binding
FR932_RS12935	COG4667	esterase of the alpha-beta hydrolase superfamily
FR932_RS12950	COG2855	membrane
FR932_RS12975	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FR932_RS12980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR932_RS12990	COG3844	kynureninase activity
FR932_RS13000	COG2175	clavaminate synthase activity
FR932_RS13010	COG0840	transmembrane signaling receptor activity
FR932_RS13045	COG0784	Response regulator, receiver
FR932_RS13045	COG2205	protein histidine kinase activity
FR932_RS13055	COG5001	Diguanylate cyclase
FR932_RS13055	COG3300	MHYT domain
FR932_RS13065	COG3397	chitin binding
FR932_RS13080	COG2990	Protein conserved in bacteria
FR932_RS13110	COG0583	DNA-binding transcription factor activity
FR932_RS13115	COG2223	nitrite transmembrane transporter activity
FR932_RS13120	COG3279	Response regulator of the LytR AlgR family
FR932_RS13125	COG3275	phosphorelay sensor kinase activity
FR932_RS13130	COG1187	pseudouridine synthase activity
FR932_RS13135	COG3097	Belongs to the UPF0267 family
FR932_RS13140	COG0626	cystathionine gamma-synthase activity
FR932_RS13190	COG0583	DNA-binding transcription factor activity
FR932_RS13195	COG2814	Major facilitator Superfamily
FR932_RS13210	COG0583	DNA-binding transcription factor activity
FR932_RS13225	COG2207	Transcriptional regulator
FR932_RS13230	COG2807	transmembrane transport
FR932_RS13235	COG0519	Catalyzes the synthesis of GMP from XMP
FR932_RS13245	COG5001	Diguanylate cyclase
FR932_RS13250	COG4251	negative regulation of phosphorylation
FR932_RS13250	COG3706	GGDEF domain
FR932_RS13250	COG2203	Gaf domain
FR932_RS13250	COG5001	Diguanylate cyclase
FR932_RS13305	COG4964	Belongs to the GSP D family
FR932_RS13335	COG0745	RESPONSE REGULATOR receiver
FR932_RS13360	COG1566	PFAM secretion protein HlyD family protein
FR932_RS13365	COG0583	DNA-binding transcription factor activity
FR932_RS13370	COG0840	transmembrane signaling receptor activity
FR932_RS13375	COG5001	Diguanylate cyclase
FR932_RS13385	COG2095	MarC family integral membrane protein
FR932_RS13405	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FR932_RS13415	COG3314	Sporulation integral membrane protein YlbJ
FR932_RS13430	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FR932_RS13450	COG1335	isochorismatase
FR932_RS13455	COG3550	peptidyl-serine autophosphorylation
FR932_RS13460	COG1396	sequence-specific DNA binding
FR932_RS13475	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FR932_RS13480	COG2801	Transposase and inactivated derivatives
FR932_RS13550	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FR932_RS13550	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FR932_RS13555	COG0509	glycine decarboxylation via glycine cleavage system
FR932_RS13560	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FR932_RS13565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FR932_RS13570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FR932_RS13585	COG0583	DNA-binding transcription factor activity
FR932_RS13595	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FR932_RS13605	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FR932_RS13610	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FR932_RS13615	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FR932_RS13620	COG1757	Na H antiporter
FR932_RS13635	COG0191	fructose-bisphosphate aldolase activity
FR932_RS13640	COG0126	phosphoglycerate kinase activity
FR932_RS13645	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FR932_RS13650	COG1946	Acyl-CoA thioesterase
FR932_RS13655	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FR932_RS13660	COG0083	homoserine kinase activity
FR932_RS13670	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
FR932_RS13675	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FR932_RS13680	COG0745	RESPONSE REGULATOR receiver
FR932_RS13685	COG0784	Response regulator, receiver
FR932_RS13685	COG0835	chemotaxis
FR932_RS13690	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FR932_RS13690	COG0047	phosphoribosylformylglycinamidine synthase activity
FR932_RS13695	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FR932_RS13715	COG2067	long-chain fatty acid transport protein
FR932_RS13730	COG1063	alcohol dehydrogenase
FR932_RS13735	COG0156	8-amino-7-oxononanoate synthase activity
FR932_RS13740	COG0281	malic enzyme
FR932_RS13745	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FR932_RS13750	COG1607	acyl-coa hydrolase
FR932_RS13755	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FR932_RS13760	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FR932_RS13790	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FR932_RS13795	COG0505	Belongs to the CarA family
FR932_RS13800	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FR932_RS13805	COG0545	Peptidyl-prolyl cis-trans isomerase
FR932_RS13815	COG0484	heat shock protein binding
FR932_RS13820	COG0443	Heat shock 70 kDa protein
FR932_RS13830	COG3909	cytochrome
FR932_RS13835	COG4999	Histidine kinase
FR932_RS13835	COG3850	Histidine kinase
FR932_RS13835	COG3437	response regulator, receiver
FR932_RS13835	COG2205	protein histidine kinase activity
FR932_RS13845	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FR932_RS13845	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
FR932_RS13865	COG0564	pseudouridine synthase activity
FR932_RS13870	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FR932_RS13875	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FR932_RS13880	COG1862	Preprotein translocase
FR932_RS13890	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FR932_RS13900	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FR932_RS13900	COG0519	Catalyzes the synthesis of GMP from XMP
FR932_RS13905	COG0516	GMP reductase activity
FR932_RS13905	COG0517	IMP dehydrogenase activity
FR932_RS13925	COG2814	Major facilitator Superfamily
FR932_RS13950	COG3852	Histidine kinase
FR932_RS13955	COG2204	response regulator
FR932_RS13965	COG4662	Binding-protein-dependent transport system inner membrane component
FR932_RS13970	COG3842	ATPase activity
FR932_RS13975	COG0746	molybdenum cofactor guanylyltransferase activity
FR932_RS13980	COG0303	'Molybdopterin
FR932_RS13990	COG0437	4 iron, 4 sulfur cluster binding
FR932_RS13995	COG3383	formate dehydrogenase (NAD+) activity
FR932_RS13995	COG0243	molybdopterin cofactor binding
FR932_RS14025	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FR932_RS14035	COG1454	alcohol dehydrogenase
FR932_RS14040	COG1024	Enoyl-CoA hydratase
FR932_RS14045	COG2824	Alkylphosphonate utilization operon protein PhnA
FR932_RS14055	COG4783	chaperone-mediated protein folding
FR932_RS14060	COG1393	Belongs to the ArsC family
FR932_RS14085	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FR932_RS14090	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FR932_RS14095	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FR932_RS14100	COG0121	glutamine amidotransferase
FR932_RS14105	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FR932_RS14110	COG1960	acyl-CoA dehydrogenase activity
FR932_RS14115	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FR932_RS14120	COG2975	iron-sulfur cluster assembly
FR932_RS14130	COG0443	Heat shock 70 kDa protein
FR932_RS14135	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FR932_RS14145	COG0822	iron-sulfur transferase activity
FR932_RS14150	COG1104	cysteine desulfurase activity
FR932_RS14155	COG1959	2 iron, 2 sulfur cluster binding
FR932_RS14175	COG4264	IucA IucC family
FR932_RS14195	COG1120	ATPase activity
FR932_RS14220	COG4667	esterase of the alpha-beta hydrolase superfamily
FR932_RS14235	COG0446	pyridine nucleotide-disulphide oxidoreductase
FR932_RS14235	COG1902	pentaerythritol trinitrate reductase activity
FR932_RS14250	COG1956	GAF domain-containing protein
FR932_RS14260	COG1160	GTP binding
FR932_RS14265	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FR932_RS14275	COG0124	histidyl-tRNA synthetase
FR932_RS14280	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FR932_RS14290	COG3063	Type IV pilus biogenesis stability protein PilW
FR932_RS14295	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FR932_RS14300	COG0105	UTP biosynthetic process
FR932_RS14310	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FR932_RS14315	COG2226	methyltransferase
FR932_RS14320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FR932_RS14325	COG0741	lytic transglycosylase activity
FR932_RS14325	COG1388	LysM domain
FR932_RS14335	COG1115	amino acid carrier protein
FR932_RS14405	COG2067	long-chain fatty acid transport protein
FR932_RS14415	COG0069	glutamate synthase activity
FR932_RS14435	COG0733	neurotransmitter:sodium symporter activity
FR932_RS14485	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FR932_RS14490	COG2011	ABC-type metal ion transport system permease component
FR932_RS14495	COG1464	Belongs to the NlpA lipoprotein family
FR932_RS14510	COG1218	3'(2'),5'-bisphosphate nucleotidase
FR932_RS14515	COG0529	Catalyzes the synthesis of activated sulfate
FR932_RS14520	COG0471	metal ion transport
FR932_RS14520	COG3273	potassium ion transport
FR932_RS14525	COG2895	sulfate adenylyltransferase (ATP) activity
FR932_RS14530	COG0175	sulfate reduction
FR932_RS14535	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FR932_RS14540	COG3047	cAMP biosynthetic process
FR932_RS14545	COG2991	Protein conserved in bacteria
FR932_RS14550	COG1477	protein flavinylation
FR932_RS14560	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FR932_RS14565	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FR932_RS14570	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FR932_RS14575	COG1805	sodium ion transport
FR932_RS14580	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FR932_RS14585	COG0271	Belongs to the BolA IbaG family
FR932_RS14590	COG2813	Specifically methylates the guanine in position
FR932_RS14600	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FR932_RS14615	COG1666	GTP binding
FR932_RS14625	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FR932_RS14630	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FR932_RS14630	COG0301	tRNA thio-modification
FR932_RS14635	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FR932_RS14645	COG2888	peptidyl-tyrosine sulfation
FR932_RS14650	COG0495	leucyl-tRNA aminoacylation
FR932_RS14655	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FR932_RS14660	COG1466	dna polymerase III delta subunit
FR932_RS14665	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FR932_RS14670	COG0799	negative regulation of ribosome biogenesis
FR932_RS14675	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FR932_RS14680	COG0768	penicillin binding
FR932_RS14685	COG0772	Belongs to the SEDS family
FR932_RS14690	COG2951	lytic endotransglycosylase activity
FR932_RS14695	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FR932_RS14700	COG1686	Belongs to the peptidase S11 family
FR932_RS14705	COG2921	Belongs to the UPF0250 family
FR932_RS14710	COG0321	lipoyl(octanoyl) transferase activity
FR932_RS14715	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FR932_RS14725	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FR932_RS14730	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FR932_RS14740	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FR932_RS14745	COG2195	Cleaves the N-terminal amino acid of tripeptides
FR932_RS14760	COG0175	sulfate reduction
FR932_RS14765	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FR932_RS14770	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FR932_RS14775	COG1024	Enoyl-CoA hydratase
FR932_RS14790	COG0028	Belongs to the TPP enzyme family
FR932_RS14795	COG3300	MHYT domain
FR932_RS14795	COG5001	Diguanylate cyclase
FR932_RS14800	COG1022	Amp-dependent synthetase and ligase
FR932_RS14810	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FR932_RS14815	COG0473	3-isopropylmalate dehydrogenase activity
FR932_RS14830	COG0830	nickel cation binding
FR932_RS14835	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FR932_RS14840	COG0829	nickel cation binding
FR932_RS14850	COG0804	urea catabolic process
FR932_RS14855	COG0832	Belongs to the urease beta subunit family
FR932_RS14895	COG1178	ABC-type Fe3 transport system permease component
FR932_RS14900	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FR932_RS14925	COG3084	Protein conserved in bacteria
FR932_RS14945	COG1121	(ABC) transporter
FR932_RS14985	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FR932_RS15000	COG0251	oxidation-reduction process
FR932_RS15015	COG1720	tRNA m6t6A37 methyltransferase activity
FR932_RS15025	COG0442	prolyl-tRNA aminoacylation
FR932_RS15030	COG4969	Belongs to the N-Me-Phe pilin family
FR932_RS15050	COG3706	GGDEF domain
FR932_RS15060	COG1418	mRNA catabolic process
FR932_RS15070	COG2252	PERMEase
FR932_RS15085	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FR932_RS15095	COG0142	geranyltranstransferase activity
FR932_RS15105	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FR932_RS15115	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FR932_RS15120	COG1388	LysM domain
FR932_RS15120	COG2373	Large extracellular alpha-helical protein
FR932_RS15120	COG4932	domain protein
FR932_RS15125	COG0513	Belongs to the DEAD box helicase family
FR932_RS15140	COG3267	Type II secretory pathway component ExeA
FR932_RS15140	COG3409	Peptidoglycan-binding domain 1 protein
FR932_RS15145	COG0617	tRNA 3'-terminal CCA addition
FR932_RS15150	COG1968	undecaprenyl-diphosphatase activity
FR932_RS15160	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FR932_RS15165	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FR932_RS15170	COG0138	bifunctional purine biosynthesis protein purh
FR932_RS15175	COG0151	Belongs to the GarS family
FR932_RS15185	COG1854	S-ribosylhomocysteine lyase activity
FR932_RS15190	COG2918	glutathione biosynthetic process
FR932_RS15195	COG0612	Peptidase, M16
FR932_RS15200	COG1238	metal cluster binding
FR932_RS15245	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FR932_RS15250	COG0527	aspartate kinase activity
FR932_RS15255	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FR932_RS15290	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FR932_RS15295	COG1047	Peptidyl-prolyl cis-trans
FR932_RS15300	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FR932_RS15305	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FR932_RS15310	COG0196	riboflavin kinase activity
FR932_RS15315	COG0728	peptidoglycan biosynthetic process
FR932_RS15320	COG0268	Binds directly to 16S ribosomal RNA
FR932_RS15345	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FR932_RS15375	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FR932_RS15380	COG0494	nUDIX hydrolase
FR932_RS15385	COG0402	S-adenosylhomocysteine deaminase activity
FR932_RS15395	COG0335	large ribosomal subunit rRNA binding
FR932_RS15400	COG0336	Belongs to the RNA methyltransferase TrmD family
FR932_RS15405	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FR932_RS15410	COG0228	four-way junction DNA binding
FR932_RS15415	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FR932_RS15420	COG4137	Cytochrome C assembly protein
FR932_RS15425	COG4536	flavin adenine dinucleotide binding
FR932_RS15430	COG0776	regulation of translation
FR932_RS15450	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FR932_RS15455	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FR932_RS15465	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FR932_RS15470	COG4942	peptidase
FR932_RS15470	COG1388	LysM domain
FR932_RS15475	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FR932_RS15480	COG0585	pseudouridine synthase activity
FR932_RS15485	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FR932_RS15490	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FR932_RS15500	COG0148	phosphopyruvate hydratase activity
FR932_RS15510	COG3956	TIGRFAM MazG family protein
FR932_RS15515	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FR932_RS15520	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FR932_RS15545	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FR932_RS15550	COG1381	Involved in DNA repair and RecF pathway recombination
FR932_RS15555	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FR932_RS15560	COG0571	ribonuclease III activity
FR932_RS15570	COG0481	GTPase activity
FR932_RS15575	COG3086	response to oxidative stress
FR932_RS15580	COG3026	antisigma factor binding
FR932_RS15590	COG1595	DNA-templated transcription, initiation
FR932_RS15595	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FR932_RS15610	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FR932_RS15620	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FR932_RS15630	COG0617	tRNA 3'-terminal CCA addition
FR932_RS15630	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FR932_RS15630	COG0517	IMP dehydrogenase activity
FR932_RS15635	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FR932_RS15645	COG4974	Belongs to the 'phage' integrase family
FR932_RS15650	COG0716	FMN binding
FR932_RS15655	COG0330	HflC and HflK could
FR932_RS15660	COG0330	HflC and HflK could
FR932_RS15665	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FR932_RS15670	COG1923	regulation of RNA biosynthetic process
FR932_RS15675	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FR932_RS15680	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FR932_RS15685	COG0860	N-Acetylmuramoyl-L-alanine amidase
FR932_RS15685	COG1388	LysM domain
FR932_RS15690	COG0802	atpase or kinase
FR932_RS15695	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FR932_RS15755	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FR932_RS15760	COG1162	GTPase activity
FR932_RS15765	COG0688	phosphatidylethanolamine metabolic process
FR932_RS15775	COG3264	Mechanosensitive ion channel
FR932_RS15775	COG1511	domain protein
FR932_RS15780	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FR932_RS15785	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FR932_RS15790	COG1509	lysine 2,3-aminomutase activity
FR932_RS15795	COG1252	NADH dehydrogenase
FR932_RS15805	COG2067	long-chain fatty acid transport protein
FR932_RS15815	COG1309	transcriptional regulator
FR932_RS15820	COG0604	alcohol dehydrogenase
FR932_RS15825	COG0737	Belongs to the 5'-nucleotidase family
FR932_RS15830	COG0523	cobalamin synthesis protein
FR932_RS15840	COG4628	conserved protein (DUF2132)
FR932_RS15855	COG0534	Mate efflux family protein
FR932_RS15860	COG1027	Aspartate ammonia-lyase
FR932_RS15865	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FR932_RS15890	COG4232	protein-disulfide reductase activity
FR932_RS15895	COG2814	Major facilitator Superfamily
FR932_RS15900	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FR932_RS15905	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FR932_RS15910	COG0511	ligase activity, forming carbon-carbon bonds
FR932_RS15915	COG0439	Biotin carboxylase
FR932_RS15920	COG3469	chitinase activity
FR932_RS15925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FR932_RS15935	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FR932_RS15945	COG1840	ABC-type Fe3 transport system, periplasmic component
FR932_RS15950	COG3842	ATPase activity
FR932_RS15965	COG0668	transmembrane transport
FR932_RS15985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR932_RS15995	COG2264	protein methyltransferase activity
FR932_RS16000	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FR932_RS16005	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FR932_RS16030	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FR932_RS16060	COG0564	pseudouridine synthase activity
FR932_RS16065	COG2204	response regulator
FR932_RS16070	COG4145	pantothenate transmembrane transporter activity
FR932_RS16085	COG1765	OsmC-like protein
FR932_RS16095	COG2084	Dehydrogenase
FR932_RS16100	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FR932_RS16110	COG0004	ammonium transporteR
FR932_RS16190	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FR932_RS16195	COG4206	TonB-dependent receptor
FR932_RS16215	COG1218	3'(2'),5'-bisphosphate nucleotidase
FR932_RS16220	COG0494	nUDIX hydrolase
FR932_RS16240	COG3156	type II secretion system protein K
FR932_RS16245	COG4795	General secretion pathway protein
FR932_RS16250	COG2165	general secretion pathway protein
FR932_RS16260	COG2165	general secretion pathway protein
FR932_RS16265	COG1459	type II secretion system
FR932_RS16270	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FR932_RS16285	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FR932_RS16290	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FR932_RS16295	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FR932_RS16300	COG2801	Transposase and inactivated derivatives
FR932_RS16305	COG2963	transposase activity
FR932_RS16310	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FR932_RS16315	COG2183	response to ionizing radiation
FR932_RS16320	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FR932_RS16325	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FR932_RS16330	COG0049	tRNA binding
FR932_RS16335	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FR932_RS16345	COG2923	Belongs to the DsrF TusC family
FR932_RS16350	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FR932_RS16355	COG0251	oxidation-reduction process
FR932_RS16415	COG2964	Protein conserved in bacteria
FR932_RS16420	COG0742	ribosomal rna small subunit methyltransferase
FR932_RS16435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FR932_RS16475	COG1999	signal sequence binding
FR932_RS16480	COG1522	sequence-specific DNA binding
FR932_RS16490	COG2204	response regulator
FR932_RS16495	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FR932_RS16500	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FR932_RS16505	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FR932_RS16520	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FR932_RS16525	COG2022	thiamine diphosphate biosynthetic process
FR932_RS16535	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FR932_RS16540	COG0352	thiamine-phosphate diphosphorylase activity
FR932_RS16545	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FR932_RS16550	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FR932_RS16555	COG0085	RNA polymerase activity
FR932_RS16560	COG0222	ribosome binding
FR932_RS16565	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FR932_RS16570	COG0081	regulation of translation
FR932_RS16575	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FR932_RS16610	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FR932_RS16610	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FR932_RS16615	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FR932_RS16630	COG1494	fructose-1,6-bisphosphatase
FR932_RS16635	COG3217	Mosc domain protein beta barrel domain protein
FR932_RS16635	COG3217	Mosc domain protein beta barrel domain protein
FR932_RS16635	COG0633	Ferredoxin
FR932_RS16635	COG0633	Ferredoxin
FR932_RS16645	COG0784	Response regulator, receiver
FR932_RS16645	COG2205	protein histidine kinase activity
FR932_RS16650	COG0513	Belongs to the DEAD box helicase family
FR932_RS16655	COG2354	Protein conserved in bacteria
FR932_RS16660	COG4681	YaeQ
FR932_RS16665	COG0243	molybdopterin cofactor binding
FR932_RS16670	COG3005	denitrification pathway
FR932_RS16675	COG4459	periplasmic nitrate reductase
FR932_RS16680	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FR932_RS16690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FR932_RS16700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FR932_RS16710	COG4232	protein-disulfide reductase activity
FR932_RS16735	COG0626	cystathionine gamma-synthase activity
FR932_RS16740	COG1522	sequence-specific DNA binding
FR932_RS16745	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FR932_RS16750	COG1301	dicarboxylic acid transport
FR932_RS16755	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FR932_RS16760	COG1074	ATP-dependent DNA helicase activity
FR932_RS16765	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FR932_RS16795	COG0438	transferase activity, transferring glycosyl groups
FR932_RS16805	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FR932_RS16815	COG1045	serine acetyltransferase
FR932_RS16825	COG0745	RESPONSE REGULATOR receiver
FR932_RS16830	COG2205	protein histidine kinase activity
FR932_RS16840	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FR932_RS16855	COG0534	Mate efflux family protein
FR932_RS16860	COG0840	transmembrane signaling receptor activity
FR932_RS16870	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FR932_RS16875	COG0835	chemotaxis
FR932_RS16880	COG2198	Histidine kinase
FR932_RS16880	COG0643	Histidine kinase
FR932_RS16885	COG0745	RESPONSE REGULATOR receiver
FR932_RS16895	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FR932_RS16900	COG2937	Belongs to the GPAT DAPAT family
FR932_RS16905	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FR932_RS16920	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FR932_RS16920	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FR932_RS16930	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FR932_RS16935	COG1519	Transferase
FR932_RS16945	COG3642	lipopolysaccharide core region biosynthetic process
FR932_RS16950	COG0859	PFAM glycosyl transferase family 9
FR932_RS16960	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FR932_RS16965	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FR932_RS16975	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FR932_RS16980	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FR932_RS16985	COG2003	Belongs to the UPF0758 family
FR932_RS16990	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FR932_RS17000	COG1309	transcriptional regulator
FR932_RS17005	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FR932_RS17010	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FR932_RS17015	COG1561	YicC-like family, N-terminal region
FR932_RS17020	COG2199	diguanylate cyclase activity
FR932_RS17035	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FR932_RS17045	COG0625	glutathione transferase activity
FR932_RS17090	COG3258	Cytochrome c
FR932_RS17115	COG3132	Protein of unknown function, DUF480
FR932_RS17135	COG0583	DNA-binding transcription factor activity
FR932_RS17140	COG1301	dicarboxylic acid transport
FR932_RS17170	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FR932_RS17180	COG0194	GDP metabolic process
FR932_RS17185	COG1758	RNA polymerase activity
FR932_RS17190	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FR932_RS17195	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FR932_RS17200	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FR932_RS17205	COG0456	acetyltransferase
FR932_RS17220	COG1295	ribonuclease BN
FR932_RS17225	COG1217	gtp-binding protein TYPA
FR932_RS17230	COG0174	glutamine synthetase
FR932_RS17240	COG3852	Histidine kinase
FR932_RS17245	COG2204	response regulator
FR932_RS17265	COG0701	Predicted permease
FR932_RS17270	COG1349	DNA-binding transcription factor activity
FR932_RS17280	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FR932_RS17300	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FR932_RS17305	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FR932_RS17305	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FR932_RS17315	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FR932_RS17355	COG0514	ATP-dependent DNA helicase (RecQ)
FR932_RS17365	COG2050	protein possibly involved in aromatic compounds catabolism
FR932_RS17370	COG2962	Rard protein
FR932_RS17380	COG0210	DNA helicase
FR932_RS17385	COG1011	Hydrolase
FR932_RS17390	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FR932_RS17400	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FR932_RS17405	COG0019	diaminopimelate decarboxylase activity
FR932_RS17415	COG1965	Belongs to the frataxin family
FR932_RS17420	COG1357	PFAM Pentapeptide repeats (8 copies)
FR932_RS17425	COG3072	Adenylate cyclase
FR932_RS17480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR932_RS17485	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FR932_RS17495	COG0181	hydroxymethylbilane synthase activity
FR932_RS17505	COG2959	enzyme of heme biosynthesis
FR932_RS17520	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FR932_RS17530	COG3118	belongs to the thioredoxin family
FR932_RS17535	COG0513	Belongs to the DEAD box helicase family
FR932_RS17540	COG0248	Ppx GppA phosphatase
FR932_RS17550	COG1309	transcriptional regulator
FR932_RS17565	COG0805	protein transport
FR932_RS17570	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FR932_RS17575	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FR932_RS17580	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FR932_RS17590	COG2226	methyltransferase
FR932_RS17595	COG0402	S-adenosylhomocysteine deaminase activity
FR932_RS17600	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FR932_RS17645	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FR932_RS17650	COG0523	cobalamin synthesis protein
FR932_RS17665	COG2217	Heavy metal translocating P-type atpase
FR932_RS17670	COG0166	Belongs to the GPI family
FR932_RS17740	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FR932_RS17750	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FR932_RS17755	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FR932_RS17760	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FR932_RS17765	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FR932_RS17770	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FR932_RS17785	COG0356	it plays a direct role in the translocation of protons across the membrane
FR932_RS17795	COG1475	DNA binding
FR932_RS17800	COG1192	Involved in chromosome partitioning
FR932_RS17805	COG0357	Ribosomal RNA small subunit methyltransferase G
FR932_RS17810	COG0445	tRNA wobble uridine modification
FR932_RS17815	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FR932_RS17825	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FR932_RS17830	COG0706	membrane insertase activity
FR932_RS17835	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FR932_RS17840	COG0594	ribonuclease P activity
FR932_RS17850	COG1126	abc transporter atp-binding protein
FR932_RS17865	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FR932_RS17875	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FR932_RS17880	COG0187	DNA topoisomerase II activity
FR932_RS17885	COG3977	Valine--pyruvate aminotransferase
FR932_RS17895	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FR932_RS17905	COG0752	glycyl-tRNA synthetase alpha subunit
FR932_RS17910	COG0425	Belongs to the sulfur carrier protein TusA family
FR932_RS17920	COG2193	ferroxidase activity
FR932_RS17945	COG1289	transmembrane transporter activity
FR932_RS17950	COG1653	transport
FR932_RS17955	COG2205	protein histidine kinase activity
FR932_RS17965	COG0183	Belongs to the thiolase family
FR932_RS17970	COG1024	Enoyl-CoA hydratase
FR932_RS17970	COG1250	3-hydroxyacyl-CoA dehydrogenase
FR932_RS17975	COG1739	Uncharacterized protein family UPF0029
FR932_RS17980	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FR932_RS18020	COG3710	Transcriptional regulator
FR932_RS18025	COG0531	amino acid
FR932_RS18030	COG1982	Orn Lys Arg decarboxylase major
FR932_RS18035	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FR932_RS18040	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FR932_RS18045	COG2076	Multidrug Resistance protein
FR932_RS18050	COG2076	Multidrug Resistance protein
FR932_RS18055	COG0583	DNA-binding transcription factor activity
FR932_RS18065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FR932_RS18070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FR932_RS18080	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FR932_RS18085	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FR932_RS18090	COG1022	Amp-dependent synthetase and ligase
FR932_RS18095	COG0204	Acyl-transferase
FR932_RS18100	COG0204	Acyl-transferase
FR932_RS18105	COG0606	chelatase, subunit chli
FR932_RS18115	COG3978	acetolactate synthase activity
FR932_RS18120	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FR932_RS18125	COG0129	dihydroxy-acid dehydratase activity
FR932_RS18130	COG0686	Belongs to the AlaDH PNT family
FR932_RS18135	COG2992	FlgJ-related protein
FR932_RS18140	COG1301	dicarboxylic acid transport
FR932_RS18145	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FR932_RS18150	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FR932_RS18180	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FR932_RS18185	COG0625	glutathione transferase activity
FR932_RS18190	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FR932_RS18195	COG0183	Belongs to the thiolase family
FR932_RS18200	COG2166	iron-sulfur cluster assembly
FR932_RS18230	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FR932_RS18235	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FR932_RS18240	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FR932_RS18250	COG3706	GGDEF domain
FR932_RS18250	COG5001	Diguanylate cyclase
FR932_RS18250	COG2203	Gaf domain
FR932_RS18250	COG4251	negative regulation of phosphorylation
FR932_RS18320	COG1322	Protein conserved in bacteria
FR932_RS18325	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FR932_RS18330	COG0569	domain protein
FR932_RS18335	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FR932_RS18335	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FR932_RS18355	COG0758	DNA mediated transformation
FR932_RS18360	COG2922	Belongs to the Smg family
FR932_RS18365	COG0551	DNA topoisomerase type I activity
FR932_RS18370	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FR932_RS18375	COG0009	L-threonylcarbamoyladenylate synthase
FR932_RS18380	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FR932_RS18385	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FR932_RS18435	COG2081	HI0933 family
FR932_RS18445	COG0561	phosphatase activity
FR932_RS18450	COG2267	carboxylic ester hydrolase activity
FR932_RS18455	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FR932_RS18460	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FR932_RS18470	COG0018	arginyl-trna synthetase
FR932_RS18475	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FR932_RS18480	COG0254	rRNA binding
FR932_RS18485	COG0281	malic enzyme
FR932_RS18500	COG0527	aspartate kinase activity
FR932_RS18500	COG0460	homoserine dehydrogenase
FR932_RS18510	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FR932_RS18545	COG0051	transcription antitermination factor activity, RNA binding
FR932_RS18550	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FR932_RS18555	COG0088	Forms part of the polypeptide exit tunnel
FR932_RS18560	COG0089	rRNA binding
FR932_RS18565	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FR932_RS18570	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FR932_RS18575	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FR932_RS18580	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FR932_RS18585	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FR932_RS18595	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FR932_RS18605	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FR932_RS18610	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FR932_RS18615	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FR932_RS18620	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FR932_RS18625	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FR932_RS18630	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FR932_RS18635	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FR932_RS18640	COG1841	ribosomal large subunit assembly
FR932_RS18645	COG0200	Binds to the 23S rRNA
FR932_RS18650	COG0201	protein transport
FR932_RS18655	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FR932_RS18660	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FR932_RS18665	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FR932_RS18680	COG0203	ribosomal protein L17
FR932_RS18720	COG4942	peptidase
FR932_RS18725	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FR932_RS18730	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FR932_RS18735	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FR932_RS18740	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FR932_RS18770	COG2095	MarC family integral membrane protein
FR932_RS18775	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FR932_RS18785	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FR932_RS18810	COG2814	Major facilitator Superfamily
FR932_RS18815	COG0629	single-stranded DNA binding
FR932_RS18855	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FR932_RS18890	COG2199	diguanylate cyclase activity
FR932_RS18890	COG2200	EAL domain
FR932_RS18920	COG3267	Type II secretory pathway component ExeA
FR932_RS18920	COG3409	Peptidoglycan-binding domain 1 protein
FR932_RS18930	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FR932_RS18935	COG1459	type II secretion system
FR932_RS18940	COG2165	general secretion pathway protein
FR932_RS18945	COG2165	general secretion pathway protein
FR932_RS18965	COG1077	Cell shape determining protein MreB Mrl
FR932_RS18970	COG1792	Involved in formation and maintenance of cell shape
FR932_RS18975	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FR932_RS18980	COG0424	maF-like protein
FR932_RS18985	COG1530	ribonuclease E activity
FR932_RS18990	COG3164	Protein of unknown function
FR932_RS18995	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FR932_RS19000	COG0312	modulator of DNA gyrase
FR932_RS19005	COG3028	Belongs to the UPF0307 family
FR932_RS19010	COG0312	modulator of DNA gyrase
FR932_RS19015	COG2239	Acts as a magnesium transporter
FR932_RS19020	COG1660	Displays ATPase and GTPase activities
FR932_RS19030	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FR932_RS19035	COG1137	ATPase activity
FR932_RS19040	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FR932_RS19050	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FR932_RS19055	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FR932_RS19055	COG0517	IMP dehydrogenase activity
FR932_RS19065	COG5007	Belongs to the BolA IbaG family
FR932_RS19070	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FR932_RS19075	COG2801	Transposase and inactivated derivatives
FR932_RS19080	COG2963	transposase activity
FR932_RS19085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FR932_RS19090	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FR932_RS19100	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FR932_RS19110	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FR932_RS19115	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FR932_RS19120	COG0723	plastoquinol--plastocyanin reductase activity
FR932_RS19125	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FR932_RS19130	COG2857	Cytochrome c1
FR932_RS19135	COG0625	glutathione transferase activity
FR932_RS19140	COG2969	positive regulation of protein catabolic process
FR932_RS19145	COG2823	Periplasmic or secreted lipoprotein
FR932_RS19150	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FR932_RS19160	COG3107	peptidoglycan biosynthetic process
FR932_RS19165	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FR932_RS19175	COG0275	rRNA processing
FR932_RS19180	COG3116	cell division
FR932_RS19185	COG0768	penicillin binding
FR932_RS19195	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FR932_RS19200	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FR932_RS19210	COG0772	Belongs to the SEDS family
FR932_RS19215	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FR932_RS19220	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FR932_RS19225	COG1181	Belongs to the D-alanine--D-alanine ligase family
FR932_RS19230	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FR932_RS19235	COG0849	cell division
FR932_RS19240	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FR932_RS19245	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FR932_RS19250	COG0739	heme binding
FR932_RS19255	COG0653	protein targeting
FR932_RS19260	COG0494	nUDIX hydrolase
FR932_RS19270	COG0237	dephospho-CoA kinase activity
FR932_RS19280	COG1459	type II secretion system
FR932_RS19285	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FR932_RS19290	COG4969	Belongs to the N-Me-Phe pilin family
FR932_RS19300	COG3577	Aspartyl protease
FR932_RS19305	COG3023	N-Acetylmuramoyl-L-alanine amidase
FR932_RS19310	COG3725	Membrane protein required for beta-lactamase induction
FR932_RS19315	COG2186	Transcriptional regulator
FR932_RS19320	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FR932_RS19325	COG0508	dehydrogenase complex catalyzes the overall conversion of
FR932_RS19330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FR932_RS19335	COG1752	Esterase of the alpha-beta hydrolase superfamily
FR932_RS19345	COG3112	Uncharacterised protein family (UPF0231)
FR932_RS19350	COG2860	membrane
FR932_RS19355	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FR932_RS19375	COG1280	lysine exporter protein (LysE YggA)
FR932_RS19380	COG0742	ribosomal rna small subunit methyltransferase
FR932_RS19385	COG0552	protein localization to endoplasmic reticulum
FR932_RS19390	COG2884	Cell division ATP-binding protein ftsE
FR932_RS19395	COG2177	Part of the ABC transporter FtsEX involved in
FR932_RS19410	COG0204	Acyl-transferase
FR932_RS19420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FR932_RS19440	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FR932_RS19470	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FR932_RS19475	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FR932_RS19485	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FR932_RS19490	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FR932_RS19500	COG0180	Tryptophanyl-tRNA synthetase
FR932_RS19505	COG2095	MarC family integral membrane protein
FR932_RS19520	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FR932_RS19525	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FR932_RS19525	COG1648	precorrin-2 dehydrogenase activity
FR932_RS19530	COG0243	molybdopterin cofactor binding
FR932_RS19600	COG0741	lytic transglycosylase activity
FR932_RS19605	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FR932_RS19610	COG1194	a g-specific adenine glycosylase
FR932_RS19620	COG3171	Protein conserved in bacteria
FR932_RS19625	COG2066	Belongs to the glutaminase family
FR932_RS19630	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FR932_RS19645	COG0762	integral membrane protein
FR932_RS19650	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FR932_RS19655	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FR932_RS19670	COG3022	response to hydroperoxide
FR932_RS19675	COG4991	sh3 domain protein
FR932_RS19680	COG0306	phosphate transporter
FR932_RS19685	COG1392	Phosphate transport regulator
FR932_RS19690	COG3025	triphosphatase activity
FR932_RS19720	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FR932_RS19725	COG1560	Kdo2-lipid A biosynthetic process
FR932_RS19730	COG1538	Outer membrane efflux protein
FR932_RS19735	COG0494	nUDIX hydrolase
FR932_RS19740	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FR932_RS19745	COG3150	esterase
FR932_RS19750	COG0187	DNA topoisomerase II activity
FR932_RS19755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR932_RS19765	COG1840	ABC-type Fe3 transport system, periplasmic component
FR932_RS19775	COG3842	ATPase activity
FR932_RS19785	COG1126	abc transporter atp-binding protein
FR932_RS19790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FR932_RS19795	COG4215	(ABC) transporter
FR932_RS19800	COG4160	amino acid transport
FR932_RS19810	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FR932_RS19815	COG0557	exoribonuclease II activity
FR932_RS19820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FR932_RS19825	COG1714	RDD family
FR932_RS19830	COG2153	protein acetylation
FR932_RS19835	COG0360	Binds together with S18 to 16S ribosomal RNA
FR932_RS19840	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FR932_RS19845	COG0359	binds to the 23S rRNA
FR932_RS19850	COG1070	Carbohydrate kinase
FR932_RS19855	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FR932_RS19875	COG0305	Participates in initiation and elongation during chromosome replication
FR932_RS19880	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FR932_RS19930	COG3621	Patatin-like phospholipase
FR932_RS19975	COG0450	alkyl hydroperoxide reductase
FR932_RS19985	COG0735	belongs to the Fur family
FR932_RS19990	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FR932_RS20020	COG0768	penicillin binding
FR932_RS20025	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
FR932_RS20030	COG5001	Diguanylate cyclase
FR932_RS20035	COG0525	valine-tRNA ligase activity
FR932_RS20040	COG2927	DNA polymerase III (CHI subunit)
FR932_RS20045	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FR932_RS20050	COG0795	lipopolysaccharide-transporting ATPase activity
FR932_RS20055	COG0795	lipopolysaccharide-transporting ATPase activity
FR932_RS20065	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FR932_RS20140	COG1028	Short-chain dehydrogenase reductase Sdr
FR932_RS20145	COG1733	regulation of RNA biosynthetic process
FR932_RS20155	COG5640	endopeptidase activity
FR932_RS20160	COG2194	sulfuric ester hydrolase activity
FR932_RS20165	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FR932_RS20175	COG2175	clavaminate synthase activity
FR932_RS20180	COG3842	ATPase activity
FR932_RS20210	COG0583	DNA-binding transcription factor activity
FR932_RS20235	COG3842	ATPase activity
FR932_RS20245	COG1176	ABC-type spermidine putrescine transport system, permease component I
FR932_RS20270	COG2832	Protein of unknown function (DUF454)
FR932_RS20285	COG1803	Methylglyoxal synthase
FR932_RS20290	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FR932_RS20300	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FR932_RS20300	COG1648	precorrin-2 dehydrogenase activity
FR932_RS20305	COG2431	L-lysine efflux transmembrane transporter activity
FR932_RS20310	COG3954	Phosphoribulokinase
FR932_RS20315	COG3089	Belongs to the UPF0270 family
FR932_RS20325	COG0811	peptide transport
FR932_RS20330	COG0811	peptide transport
FR932_RS20335	COG0848	biopolymer transport protein
FR932_RS20355	COG0488	(ABC) transporter
FR932_RS20365	COG1047	Peptidyl-prolyl cis-trans
FR932_RS20380	COG0545	Peptidyl-prolyl cis-trans isomerase
FR932_RS20385	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FR932_RS20395	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FR932_RS20400	COG0564	pseudouridine synthase activity
FR932_RS20410	COG0542	response to heat
FR932_RS20415	COG1115	amino acid carrier protein
FR932_RS20420	COG0714	Associated with various cellular activities
FR932_RS20455	COG4585	Histidine kinase
FR932_RS20465	COG1566	PFAM secretion protein HlyD family protein
FR932_RS20480	COG0840	transmembrane signaling receptor activity
FR932_RS20520	COG0800	Aldolase
FR932_RS20525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FR932_RS20530	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FR932_RS20535	COG4535	Mg2 and Co2 transporter CorC
FR932_RS20540	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FR932_RS20545	COG1702	phosphate starvation-inducible protein PhoH
FR932_RS20550	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FR932_RS20555	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FR932_RS20620	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FR932_RS20625	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FR932_RS20630	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FR932_RS20635	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FR932_RS20640	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FR932_RS20645	COG2890	protein-(glutamine-N5) methyltransferase activity
FR932_RS20655	COG2912	Transglutaminase-like superfamily
FR932_RS20660	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FR932_RS20665	COG0583	DNA-binding transcription factor activity
FR932_RS20670	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FR932_RS20680	COG0473	3-isopropylmalate dehydrogenase activity
FR932_RS20685	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FR932_RS20690	COG1611	Belongs to the LOG family
FR932_RS20705	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FR932_RS20705	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FR932_RS20740	COG3098	single-species biofilm formation
FR932_RS20750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FR932_RS20750	COG1263	PTS System
FR932_RS20755	COG2171	N-acyltransferase activity
FR932_RS20765	COG0024	Methionine aminopeptidase
FR932_RS20775	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FR932_RS20780	COG0528	UMP kinase activity
FR932_RS20790	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FR932_RS20795	COG0575	Belongs to the CDS family
FR932_RS20800	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FR932_RS20805	COG0750	zinc metalloprotease
FR932_RS20815	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FR932_RS20820	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FR932_RS20825	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FR932_RS20830	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FR932_RS20835	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FR932_RS20845	COG0587	DNA-directed DNA polymerase activity
FR932_RS20850	COG0825	malonyl-CoA metabolic process
FR932_RS20855	COG0037	tRNA processing
FR932_RS20860	COG0748	coenzyme F420 binding
FR932_RS20865	COG3721	Heme iron utilization protein
FR932_RS20875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FR932_RS20885	COG2966	Psort location CytoplasmicMembrane, score
FR932_RS20890	COG3610	response to peptide
FR932_RS20900	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FR932_RS20905	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FR932_RS20910	COG2967	ApaG domain
FR932_RS20920	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FR932_RS20925	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FR932_RS20930	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FR932_RS20935	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FR932_RS20945	COG0564	pseudouridine synthase activity
FR932_RS20950	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FR932_RS20995	COG1022	Amp-dependent synthetase and ligase
FR932_RS21000	COG1227	inorganic diphosphatase activity
FR932_RS21005	COG0659	secondary active sulfate transmembrane transporter activity
FR932_RS21010	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FR932_RS21015	COG0513	Belongs to the DEAD box helicase family
FR932_RS21020	COG1770	oligopeptidase
FR932_RS21035	COG3706	GGDEF domain
FR932_RS21040	COG0084	hydrolase, TatD family'
FR932_RS21045	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FR932_RS21050	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FR932_RS21055	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FR932_RS21060	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FR932_RS21065	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FR932_RS21070	COG0813	purine-nucleoside phosphorylase activity
FR932_RS21075	COG0488	(ABC) transporter
FR932_RS21080	COG5002	protein histidine kinase activity
FR932_RS21080	COG3447	MASE1 domain protein
FR932_RS21080	COG5001	Diguanylate cyclase
FR932_RS21090	COG0560	Phosphoserine phosphatase
FR932_RS21100	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FR932_RS21115	COG0163	prenyltransferase activity
FR932_RS21135	COG1131	(ABC) transporter
FR932_RS21140	COG0842	Transport permease protein
FR932_RS21175	COG0438	transferase activity, transferring glycosyl groups
FR932_RS21175	COG0297	glycogen (starch) synthase activity
FR932_RS21210	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FR932_RS21215	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FR932_RS21220	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FR932_RS21225	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FR932_RS21230	COG1086	Polysaccharide biosynthesis protein
FR932_RS21235	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FR932_RS21245	COG2089	acid synthase
FR932_RS21250	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FR932_RS21265	COG1083	cytidylyl-transferase
FR932_RS21270	COG1181	Belongs to the D-alanine--D-alanine ligase family
FR932_RS21300	COG1086	Polysaccharide biosynthesis protein
FR932_RS21310	COG1083	cytidylyl-transferase
FR932_RS21320	COG2089	acid synthase
FR932_RS21335	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FR932_RS21340	COG3381	protein complex oligomerization
FR932_RS21345	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FR932_RS21360	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FR932_RS21365	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FR932_RS21365	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FR932_RS21380	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FR932_RS21385	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons