locus-tag	class	description
DIU31_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DIU31_RS00025	COG2442	InterPro IPR007367
DIU31_RS00050	COG1704	LemA family
DIU31_RS00060	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
DIU31_RS00080	COG1132	(ABC) transporter
DIU31_RS00085	COG0859	PFAM glycosyl transferase family 9
DIU31_RS00090	COG1216	Glycosyl transferase, family 2
DIU31_RS00100	COG0859	PFAM glycosyl transferase family 9
DIU31_RS00115	COG0006	proline dipeptidase activity
DIU31_RS00130	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DIU31_RS00145	COG0300	oxidoreductase activity
DIU31_RS00150	COG0488	(ABC) transporter
DIU31_RS00155	COG0542	response to heat
DIU31_RS00170	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DIU31_RS00175	COG0497	DNA recombination
DIU31_RS00185	COG3682	Transcriptional regulator
DIU31_RS00190	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DIU31_RS00195	COG1595	DNA-templated transcription, initiation
DIU31_RS00245	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DIU31_RS00250	COG4974	Belongs to the 'phage' integrase family
DIU31_RS00295	COG0250	Participates in transcription elongation, termination and antitermination
DIU31_RS00300	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DIU31_RS00305	COG0081	regulation of translation
DIU31_RS00310	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DIU31_RS00315	COG0222	ribosome binding
DIU31_RS00320	COG0085	RNA polymerase activity
DIU31_RS00325	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DIU31_RS00350	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DIU31_RS00365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DIU31_RS00370	COG0110	maltose O-acetyltransferase activity
DIU31_RS00400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DIU31_RS00405	COG0673	inositol 2-dehydrogenase activity
DIU31_RS00410	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DIU31_RS00415	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS00420	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DIU31_RS00440	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
DIU31_RS00445	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DIU31_RS00450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DIU31_RS00455	COG3693	PFAM glycoside hydrolase, family 10
DIU31_RS00455	COG3507	Belongs to the glycosyl hydrolase 43 family
DIU31_RS00455	COG2382	esterase
DIU31_RS00475	COG0175	sulfate reduction
DIU31_RS00490	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DIU31_RS00505	COG0617	tRNA 3'-terminal CCA addition
DIU31_RS00505	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DIU31_RS00505	COG0517	IMP dehydrogenase activity
DIU31_RS00510	COG0009	L-threonylcarbamoyladenylate synthase
DIU31_RS00520	COG2171	N-acyltransferase activity
DIU31_RS00535	COG0590	tRNA wobble adenosine to inosine editing
DIU31_RS00545	COG0187	DNA topoisomerase II activity
DIU31_RS00570	COG0359	binds to the 23S rRNA
DIU31_RS00575	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DIU31_RS00580	COG0360	Binds together with S18 to 16S ribosomal RNA
DIU31_RS00600	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DIU31_RS00615	COG0538	isocitrate dehydrogenase activity
DIU31_RS00620	COG1482	cell wall glycoprotein biosynthetic process
DIU31_RS00630	COG2201	protein-glutamate methylesterase activity
DIU31_RS00650	COG3185	4-Hydroxyphenylpyruvate dioxygenase
DIU31_RS00675	COG3034	peptidoglycan biosynthetic process
DIU31_RS00680	COG3279	Response regulator of the LytR AlgR family
DIU31_RS00685	COG3275	phosphorelay sensor kinase activity
DIU31_RS00735	COG3186	Phenylalanine-4-hydroxylase
DIU31_RS00740	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS00775	COG0629	single-stranded DNA binding
DIU31_RS00820	COG0531	amino acid
DIU31_RS00830	COG2095	MarC family integral membrane protein
DIU31_RS00845	COG0519	Catalyzes the synthesis of GMP from XMP
DIU31_RS00845	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DIU31_RS00880	COG1127	ABC transporter
DIU31_RS00885	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DIU31_RS00890	COG2207	Transcriptional regulator
DIU31_RS00895	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DIU31_RS00900	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
DIU31_RS00905	COG2942	2-epimerase
DIU31_RS00910	COG4124	Belongs to the glycosyl hydrolase 26 family
DIU31_RS00915	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DIU31_RS00925	COG0738	Major facilitator superfamily
DIU31_RS00935	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DIU31_RS00940	COG3527	Alpha-acetolactate decarboxylase
DIU31_RS00990	COG3345	alpha-galactosidase
DIU31_RS01015	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DIU31_RS01030	COG5002	protein histidine kinase activity
DIU31_RS01035	COG0745	RESPONSE REGULATOR receiver
DIU31_RS01085	COG3254	rhamnose metabolic process
DIU31_RS01095	COG2721	sulfolactate sulfo-lyase activity
DIU31_RS01100	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS01110	COG0179	Fumarylacetoacetate (FAA) hydrolase
DIU31_RS01115	COG3618	amidohydrolase
DIU31_RS01155	COG1070	Carbohydrate kinase
DIU31_RS01160	COG4952	isomerase
DIU31_RS01165	COG3347	Dehydrogenase
DIU31_RS01165	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS01175	COG1070	Carbohydrate kinase
DIU31_RS01190	COG0735	belongs to the Fur family
DIU31_RS01195	COG0860	N-Acetylmuramoyl-L-alanine amidase
DIU31_RS01200	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DIU31_RS01205	COG0564	pseudouridine synthase activity
DIU31_RS01210	COG2515	1-aminocyclopropane-1-carboxylate deaminase
DIU31_RS01215	COG5002	protein histidine kinase activity
DIU31_RS01230	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DIU31_RS01235	COG0386	Belongs to the glutathione peroxidase family
DIU31_RS01245	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DIU31_RS01250	COG0735	belongs to the Fur family
DIU31_RS01255	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DIU31_RS01260	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DIU31_RS01270	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DIU31_RS01275	COG3876	Protein conserved in bacteria
DIU31_RS01280	COG4591	ABC-type transport system involved in lipoprotein release permease component
DIU31_RS01305	COG3956	TIGRFAM MazG family protein
DIU31_RS01340	COG3590	peptidase
DIU31_RS01345	COG0525	valine-tRNA ligase activity
DIU31_RS01350	COG2205	protein histidine kinase activity
DIU31_RS01350	COG0784	Response regulator, receiver
DIU31_RS01380	COG0529	Catalyzes the synthesis of activated sulfate
DIU31_RS01410	COG1846	Transcriptional regulator
DIU31_RS01420	COG0237	dephospho-CoA kinase activity
DIU31_RS01430	COG1862	Preprotein translocase
DIU31_RS01440	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DIU31_RS01455	COG1132	(ABC) transporter
DIU31_RS01465	COG2239	Acts as a magnesium transporter
DIU31_RS01470	COG0012	GTP binding
DIU31_RS01480	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS01490	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS01500	COG3119	arylsulfatase activity
DIU31_RS01570	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DIU31_RS01570	COG0551	DNA topoisomerase type I activity
DIU31_RS01610	COG0737	Belongs to the 5'-nucleotidase family
DIU31_RS01620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DIU31_RS01625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DIU31_RS01630	COG4232	protein-disulfide reductase activity
DIU31_RS01645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DIU31_RS01650	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DIU31_RS01670	COG2814	Major facilitator Superfamily
DIU31_RS01675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DIU31_RS01675	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DIU31_RS01680	COG0640	Transcriptional regulator
DIU31_RS01715	COG0464	growth
DIU31_RS01770	COG4206	TonB-dependent receptor
DIU31_RS01770	COG1629	transport
DIU31_RS01775	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DIU31_RS01785	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DIU31_RS01785	COG0574	Belongs to the PEP-utilizing enzyme family
DIU31_RS01790	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
DIU31_RS01795	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
DIU31_RS01815	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DIU31_RS01855	COG1309	transcriptional regulator
DIU31_RS01860	COG2814	Major facilitator Superfamily
DIU31_RS01870	COG1556	Lactate utilization protein
DIU31_RS01875	COG1139	Iron-sulfur cluster binding protein
DIU31_RS01880	COG0247	lactate metabolic process
DIU31_RS01890	COG3250	beta-galactosidase activity
DIU31_RS01895	COG0165	Argininosuccinate lyase
DIU31_RS01900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DIU31_RS01905	COG4895	conserved protein (DUF2196)
DIU31_RS01920	COG2207	Transcriptional regulator
DIU31_RS01965	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS01970	COG1801	Protein of unknown function DUF72
DIU31_RS01980	COG2755	lipolytic protein G-D-S-L family
DIU31_RS01980	COG0657	acetylesterase activity
DIU31_RS01995	COG0321	lipoyl(octanoyl) transferase activity
DIU31_RS01995	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DIU31_RS02015	COG0563	adenylate kinase activity
DIU31_RS02025	COG1674	ftsk spoiiie
DIU31_RS02030	COG0666	response to abiotic stimulus
DIU31_RS02035	COG2207	Transcriptional regulator
DIU31_RS02035	COG1917	Cupin 2, conserved barrel domain protein
DIU31_RS02060	COG0788	formyltetrahydrofolate deformylase activity
DIU31_RS02080	COG0167	dihydroorotate dehydrogenase activity
DIU31_RS02095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DIU31_RS02110	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
DIU31_RS02125	COG0488	(ABC) transporter
DIU31_RS02160	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DIU31_RS02170	COG0205	6-phosphofructokinase activity
DIU31_RS02195	COG0463	Glycosyl transferase, family 2
DIU31_RS02200	COG0726	polysaccharide deacetylase
DIU31_RS02215	COG1917	Cupin 2, conserved barrel domain protein
DIU31_RS02215	COG4977	sequence-specific DNA binding
DIU31_RS02235	COG4771	TonB-dependent receptor
DIU31_RS02240	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DIU31_RS02345	COG1278	Cold shock
DIU31_RS02355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DIU31_RS02365	COG0019	diaminopimelate decarboxylase activity
DIU31_RS02370	COG0527	aspartate kinase activity
DIU31_RS02395	COG3852	Histidine kinase
DIU31_RS02405	COG3275	phosphorelay sensor kinase activity
DIU31_RS02440	COG2205	protein histidine kinase activity
DIU31_RS02450	COG0432	Pfam Uncharacterised protein family UPF0047
DIU31_RS02510	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DIU31_RS02535	COG1595	DNA-templated transcription, initiation
DIU31_RS02545	COG3250	beta-galactosidase activity
DIU31_RS02575	COG3047	cAMP biosynthetic process
DIU31_RS02585	COG0720	synthase
DIU31_RS02605	COG3278	Belongs to the heme-copper respiratory oxidase family
DIU31_RS02615	COG2010	Cytochrome c
DIU31_RS02620	COG0348	domain, Protein
DIU31_RS02640	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DIU31_RS02645	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DIU31_RS02655	COG4191	Histidine kinase
DIU31_RS02665	COG3254	rhamnose metabolic process
DIU31_RS02675	COG0738	Major facilitator superfamily
DIU31_RS02680	COG4948	Mandelate Racemase Muconate Lactonizing
DIU31_RS02695	COG3292	Two component regulator propeller
DIU31_RS02695	COG2205	protein histidine kinase activity
DIU31_RS02695	COG0745	RESPONSE REGULATOR receiver
DIU31_RS02705	COG1472	Belongs to the glycosyl hydrolase 3 family
DIU31_RS02710	COG3250	beta-galactosidase activity
DIU31_RS02735	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DIU31_RS02735	COG5297	Belongs to the glycosyl hydrolase family 6
DIU31_RS02745	COG0561	phosphatase activity
DIU31_RS02750	COG4771	TonB-dependent receptor
DIU31_RS02760	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DIU31_RS02770	COG3292	Two component regulator propeller
DIU31_RS02770	COG2205	protein histidine kinase activity
DIU31_RS02770	COG0745	RESPONSE REGULATOR receiver
DIU31_RS02780	COG0702	epimerase
DIU31_RS02785	COG4771	TonB-dependent receptor
DIU31_RS02795	COG2814	Major facilitator Superfamily
DIU31_RS02810	COG2188	Transcriptional regulator
DIU31_RS02820	COG4771	TonB-dependent receptor
DIU31_RS02830	COG4771	TonB-dependent receptor
DIU31_RS02835	COG0702	epimerase
DIU31_RS02850	COG0702	epimerase
DIU31_RS02910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DIU31_RS02945	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS02950	COG1733	regulation of RNA biosynthetic process
DIU31_RS02955	COG1917	Cupin 2, conserved barrel domain protein
DIU31_RS02955	COG4977	sequence-specific DNA binding
DIU31_RS02975	COG1629	transport
DIU31_RS02975	COG4206	TonB-dependent receptor
DIU31_RS02985	COG2197	response regulator
DIU31_RS02995	COG3279	Response regulator of the LytR AlgR family
DIU31_RS03000	COG3275	phosphorelay sensor kinase activity
DIU31_RS03010	COG2353	YceI-like domain
DIU31_RS03025	COG0596	Alpha beta hydrolase
DIU31_RS03095	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DIU31_RS03115	COG0745	RESPONSE REGULATOR receiver
DIU31_RS03145	COG0745	RESPONSE REGULATOR receiver
DIU31_RS03150	COG1366	Belongs to the anti-sigma-factor antagonist family
DIU31_RS03150	COG2202	Pas domain
DIU31_RS03175	COG2823	Periplasmic or secreted lipoprotein
DIU31_RS03180	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DIU31_RS03210	COG5002	protein histidine kinase activity
DIU31_RS03240	COG2205	protein histidine kinase activity
DIU31_RS03245	COG4771	TonB-dependent receptor
DIU31_RS03250	COG0702	epimerase
DIU31_RS03265	COG3250	beta-galactosidase activity
DIU31_RS03275	COG0745	RESPONSE REGULATOR receiver
DIU31_RS03275	COG2205	protein histidine kinase activity
DIU31_RS03275	COG3292	Two component regulator propeller
DIU31_RS03290	COG4771	TonB-dependent receptor
DIU31_RS03310	COG3250	beta-galactosidase activity
DIU31_RS03350	COG2814	Major facilitator Superfamily
DIU31_RS03380	COG0028	Belongs to the TPP enzyme family
DIU31_RS03390	COG1017	nitric oxide dioxygenase activity
DIU31_RS03390	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DIU31_RS03395	COG3663	DNA glycosylase
DIU31_RS03405	COG0656	L-ascorbic acid biosynthetic process
DIU31_RS03480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DIU31_RS03485	COG1611	Belongs to the LOG family
DIU31_RS03495	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DIU31_RS03505	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS03515	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DIU31_RS03520	COG0133	tryptophan synthase activity
DIU31_RS03525	COG0159	tryptophan synthase activity
DIU31_RS03530	COG0009	L-threonylcarbamoyladenylate synthase
DIU31_RS03540	COG2353	YceI-like domain
DIU31_RS03545	COG0069	glutamate synthase activity
DIU31_RS03560	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DIU31_RS03575	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
DIU31_RS03585	COG4122	O-methyltransferase activity
DIU31_RS03600	COG0745	RESPONSE REGULATOR receiver
DIU31_RS03605	COG0745	RESPONSE REGULATOR receiver
DIU31_RS03610	COG2610	gluconate transmembrane transporter activity
DIU31_RS03630	COG2814	Major facilitator Superfamily
DIU31_RS03645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DIU31_RS03650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DIU31_RS03670	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DIU31_RS03685	COG0004	ammonium transporteR
DIU31_RS03700	COG0004	ammonium transporteR
DIU31_RS03705	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
DIU31_RS03765	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DIU31_RS03770	COG0346	lactoylglutathione lyase activity
DIU31_RS03775	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DIU31_RS03785	COG0328	RNA-DNA hybrid ribonuclease activity
DIU31_RS03800	COG2205	protein histidine kinase activity
DIU31_RS03805	COG0784	Response regulator, receiver
DIU31_RS03805	COG4191	Histidine kinase
DIU31_RS03820	COG4221	oxidoreductase activity
DIU31_RS03850	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS03865	COG0778	Nitroreductase
DIU31_RS03870	COG1741	Belongs to the pirin family
DIU31_RS03905	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DIU31_RS03940	COG1484	DNA-dependent DNA replication
DIU31_RS03945	COG4584	PFAM Integrase catalytic
DIU31_RS03950	COG3604	Transcriptional regulator
DIU31_RS03955	COG3604	Transcriptional regulator
DIU31_RS03970	COG0783	Belongs to the Dps family
DIU31_RS04045	COG3604	Transcriptional regulator
DIU31_RS04060	COG1609	Transcriptional regulator
DIU31_RS04090	COG1629	transport
DIU31_RS04115	COG1609	Transcriptional regulator
DIU31_RS04195	COG4771	TonB-dependent receptor
DIU31_RS04205	COG0745	RESPONSE REGULATOR receiver
DIU31_RS04205	COG2205	protein histidine kinase activity
DIU31_RS04205	COG3292	Two component regulator propeller
DIU31_RS04205	COG2205	protein histidine kinase activity
DIU31_RS04205	COG3292	Two component regulator propeller
DIU31_RS04205	COG0745	RESPONSE REGULATOR receiver
DIU31_RS04210	COG4771	TonB-dependent receptor
DIU31_RS04235	COG3250	beta-galactosidase activity
DIU31_RS04245	COG3254	rhamnose metabolic process
DIU31_RS04270	COG1629	transport
DIU31_RS04290	COG0584	glycerophosphoryl diester phosphodiesterase
DIU31_RS04310	COG0358	DNA primase activity
DIU31_RS04310	COG0305	Participates in initiation and elongation during chromosome replication
DIU31_RS04320	COG0783	Belongs to the Dps family
DIU31_RS04335	COG2080	2 iron, 2 sulfur cluster binding
DIU31_RS04340	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
DIU31_RS04345	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DIU31_RS04350	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DIU31_RS04355	COG1252	NADH dehydrogenase
DIU31_RS04365	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DIU31_RS04375	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DIU31_RS04390	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DIU31_RS04420	COG1629	transport
DIU31_RS04425	COG0702	epimerase
DIU31_RS04475	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DIU31_RS04490	COG4771	TonB-dependent receptor
DIU31_RS04490	COG4771	TonB-dependent receptor
DIU31_RS04530	COG0513	Belongs to the DEAD box helicase family
DIU31_RS04540	COG2340	Cysteine-rich secretory protein family
DIU31_RS04560	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DIU31_RS04595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DIU31_RS04610	COG0436	Aminotransferase
DIU31_RS04615	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DIU31_RS04625	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DIU31_RS04635	COG1368	sulfuric ester hydrolase activity
DIU31_RS04670	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DIU31_RS04680	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DIU31_RS04685	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DIU31_RS04690	COG0745	RESPONSE REGULATOR receiver
DIU31_RS04695	COG0798	PFAM Bile acid sodium symporter
DIU31_RS04700	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DIU31_RS04730	COG1085	galactose-1-phosphate uridylyltransferase
DIU31_RS04735	COG1011	Hydrolase
DIU31_RS04755	COG0174	glutamine synthetase
DIU31_RS04765	COG0564	pseudouridine synthase activity
DIU31_RS04780	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DIU31_RS04785	COG0303	'Molybdopterin
DIU31_RS04790	COG0315	cyclic pyranopterin monophosphate synthase activity
DIU31_RS04795	COG0746	molybdenum cofactor guanylyltransferase activity
DIU31_RS04810	COG0314	molybdopterin synthase activity
DIU31_RS04825	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DIU31_RS04870	COG1472	Belongs to the glycosyl hydrolase 3 family
DIU31_RS04920	COG1940	carbohydrate kinase activity
DIU31_RS04930	COG1252	NADH dehydrogenase
DIU31_RS04935	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DIU31_RS04940	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DIU31_RS04945	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DIU31_RS04950	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DIU31_RS04955	COG2084	Dehydrogenase
DIU31_RS04975	COG0343	queuine tRNA-ribosyltransferase activity
DIU31_RS04980	COG1215	transferase activity, transferring glycosyl groups
DIU31_RS04985	COG1595	DNA-templated transcription, initiation
DIU31_RS04990	COG0357	Ribosomal RNA small subunit methyltransferase G
DIU31_RS05010	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DIU31_RS05010	COG0758	DNA mediated transformation
DIU31_RS05030	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DIU31_RS05030	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DIU31_RS05035	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DIU31_RS05040	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DIU31_RS05040	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DIU31_RS05045	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DIU31_RS05045	COG1796	DNA polymerase
DIU31_RS05050	COG0616	signal peptide processing
DIU31_RS05055	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DIU31_RS05055	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DIU31_RS05070	COG1183	phosphatidylcholine synthase activity
DIU31_RS05080	COG0284	orotidine-5'-phosphate decarboxylase activity
DIU31_RS05085	COG0484	heat shock protein binding
DIU31_RS05090	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DIU31_RS05095	COG2884	Cell division ATP-binding protein ftsE
DIU31_RS05110	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DIU31_RS05115	COG0791	NLP P60 protein
DIU31_RS05125	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DIU31_RS05125	COG0140	phosphoribosyl-ATP diphosphatase activity
DIU31_RS05130	COG0107	imidazoleglycerol-phosphate synthase activity
DIU31_RS05135	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DIU31_RS05140	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DIU31_RS05145	COG0131	Imidazoleglycerol-phosphate dehydratase
DIU31_RS05150	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DIU31_RS05160	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DIU31_RS05165	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DIU31_RS05185	COG0393	Putative heavy-metal-binding
DIU31_RS05205	COG3622	Belongs to the hyi family
DIU31_RS05210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DIU31_RS05230	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DIU31_RS05250	COG0667	Aldo Keto reductase
DIU31_RS05280	COG2954	triphosphatase activity
DIU31_RS05290	COG0640	Transcriptional regulator
DIU31_RS05305	COG0069	glutamate synthase activity
DIU31_RS05305	COG0070	glutamate synthase
DIU31_RS05305	COG0067	glutamate synthase
DIU31_RS05310	COG3123	guanosine phosphorylase activity
DIU31_RS05325	COG0110	maltose O-acetyltransferase activity
DIU31_RS05330	COG3739	integral membrane protein
DIU31_RS05350	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DIU31_RS05355	COG0791	NLP P60 protein
DIU31_RS05380	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DIU31_RS05410	COG2255	four-way junction helicase activity
DIU31_RS05415	COG0463	Glycosyl transferase, family 2
DIU31_RS05430	COG0183	Belongs to the thiolase family
DIU31_RS05450	COG1480	7TM receptor with intracellular HD hydrolase
DIU31_RS05460	COG4974	Belongs to the 'phage' integrase family
DIU31_RS05480	COG1278	Cold shock
DIU31_RS05485	COG1278	Cold shock
DIU31_RS05505	COG0745	RESPONSE REGULATOR receiver
DIU31_RS05560	COG0745	RESPONSE REGULATOR receiver
DIU31_RS05560	COG3292	Two component regulator propeller
DIU31_RS05560	COG2205	protein histidine kinase activity
DIU31_RS05585	COG1309	transcriptional regulator
DIU31_RS05595	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
DIU31_RS05630	COG4771	TonB-dependent receptor
DIU31_RS05645	COG4585	Histidine kinase
DIU31_RS05670	COG1522	sequence-specific DNA binding
DIU31_RS05690	COG2207	Transcriptional regulator
DIU31_RS05690	COG0662	Cupin 2, conserved barrel domain protein
DIU31_RS05710	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
DIU31_RS05715	COG1396	sequence-specific DNA binding
DIU31_RS05760	COG0784	Response regulator, receiver
DIU31_RS05760	COG5002	protein histidine kinase activity
DIU31_RS05815	COG0745	RESPONSE REGULATOR receiver
DIU31_RS05830	COG4974	Belongs to the 'phage' integrase family
DIU31_RS06005	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DIU31_RS06010	COG0587	DNA-directed DNA polymerase activity
DIU31_RS06035	COG3285	dna ligase
DIU31_RS06035	COG1793	dna ligase
DIU31_RS06170	COG4771	TonB-dependent receptor
DIU31_RS06205	COG4974	Belongs to the 'phage' integrase family
DIU31_RS06240	COG3547	Transposase (IS116 IS110 IS902 family)
DIU31_RS06265	COG0443	Heat shock 70 kDa protein
DIU31_RS06325	COG0110	maltose O-acetyltransferase activity
DIU31_RS06340	COG2133	pyrroloquinoline quinone binding
DIU31_RS06435	COG0367	asparagine synthase
DIU31_RS06450	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DIU31_RS06455	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DIU31_RS06470	COG1216	Glycosyl transferase, family 2
DIU31_RS06480	COG2244	polysaccharide biosynthetic process
DIU31_RS06485	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DIU31_RS06495	COG0489	protein tyrosine kinase activity
DIU31_RS06495	COG3206	protein involved in exopolysaccharide biosynthesis
DIU31_RS06505	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DIU31_RS06525	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
DIU31_RS06580	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DIU31_RS06590	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DIU31_RS06595	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DIU31_RS06600	COG3959	Transketolase, thiamine diphosphate binding domain
DIU31_RS06605	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DIU31_RS06660	COG0018	arginyl-trna synthetase
DIU31_RS06670	COG1250	3-hydroxyacyl-CoA dehydrogenase
DIU31_RS06675	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DIU31_RS06680	COG0156	8-amino-7-oxononanoate synthase activity
DIU31_RS06700	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DIU31_RS06715	COG0823	Involved in the tonB-independent uptake of proteins
DIU31_RS06725	COG2326	polyphosphate kinase activity
DIU31_RS06735	COG3537	Alpha-1,2-mannosidase
DIU31_RS06745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DIU31_RS06755	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DIU31_RS06760	COG0436	Aminotransferase
DIU31_RS06770	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DIU31_RS06780	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DIU31_RS06850	COG0531	amino acid
DIU31_RS06855	COG4303	Ethanolamine ammonia lyase large subunit
DIU31_RS06875	COG0326	Molecular chaperone. Has ATPase activity
DIU31_RS06880	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DIU31_RS06885	COG0191	fructose-bisphosphate aldolase activity
DIU31_RS06905	COG0667	Aldo Keto reductase
DIU31_RS06915	COG4941	Belongs to the sigma-70 factor family
DIU31_RS06920	COG1472	Belongs to the glycosyl hydrolase 3 family
DIU31_RS06925	COG4206	TonB-dependent receptor
DIU31_RS06925	COG1629	transport
DIU31_RS06950	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DIU31_RS06985	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DIU31_RS07000	COG0439	Biotin carboxylase
DIU31_RS07015	COG0307	riboflavin synthase, alpha
DIU31_RS07035	COG0443	Heat shock 70 kDa protein
DIU31_RS07040	COG0667	Aldo Keto reductase
DIU31_RS07045	COG4999	Histidine kinase
DIU31_RS07045	COG3850	Histidine kinase
DIU31_RS07045	COG3437	response regulator, receiver
DIU31_RS07045	COG2205	protein histidine kinase activity
DIU31_RS07050	COG2207	Transcriptional regulator
DIU31_RS07080	COG4120	Belongs to the binding-protein-dependent transport system permease family
DIU31_RS07085	COG3842	ATPase activity
DIU31_RS07120	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DIU31_RS07125	COG2363	Small membrane protein
DIU31_RS07140	COG1214	PFAM Peptidase M22, glycoprotease
DIU31_RS07150	COG0594	ribonuclease P activity
DIU31_RS07155	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DIU31_RS07195	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DIU31_RS07200	COG1104	cysteine desulfurase activity
DIU31_RS07205	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DIU31_RS07220	COG0823	Involved in the tonB-independent uptake of proteins
DIU31_RS07220	COG1506	peptidase
DIU31_RS07225	COG0527	aspartate kinase activity
DIU31_RS07230	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DIU31_RS07235	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DIU31_RS07240	COG1252	NADH dehydrogenase
DIU31_RS07250	COG2808	Putative FMN-binding domain
DIU31_RS07260	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DIU31_RS07270	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DIU31_RS07280	COG0137	argininosuccinate synthase activity
DIU31_RS07290	COG0492	ferredoxin-NADP+ reductase activity
DIU31_RS07325	COG3279	Response regulator of the LytR AlgR family
DIU31_RS07335	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DIU31_RS07340	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DIU31_RS07345	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DIU31_RS07350	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DIU31_RS07355	COG1132	(ABC) transporter
DIU31_RS07370	COG1702	phosphate starvation-inducible protein PhoH
DIU31_RS07375	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DIU31_RS07385	COG1234	tRNA 3'-trailer cleavage
DIU31_RS07395	COG1388	LysM domain
DIU31_RS07395	COG0860	N-Acetylmuramoyl-L-alanine amidase
DIU31_RS07405	COG1546	Belongs to the CinA family
DIU31_RS07405	COG1058	Belongs to the CinA family
DIU31_RS07410	COG0508	dehydrogenase complex catalyzes the overall conversion of
DIU31_RS07415	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DIU31_RS07420	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DIU31_RS07425	COG1914	H( )-stimulated, divalent metal cation uptake system
DIU31_RS07430	COG1321	iron dependent repressor
DIU31_RS07430	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DIU31_RS07435	COG1522	sequence-specific DNA binding
DIU31_RS07440	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DIU31_RS07455	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DIU31_RS07470	COG0612	Peptidase, M16
DIU31_RS07500	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DIU31_RS07540	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DIU31_RS07555	COG4771	TonB-dependent receptor
DIU31_RS07585	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DIU31_RS07595	COG1477	protein flavinylation
DIU31_RS07625	COG1073	alpha beta
DIU31_RS07630	COG3537	Alpha-1,2-mannosidase
DIU31_RS07650	COG0702	epimerase
DIU31_RS07665	COG4771	TonB-dependent receptor
DIU31_RS07670	COG0702	epimerase
DIU31_RS07675	COG4771	TonB-dependent receptor
DIU31_RS07680	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DIU31_RS07695	COG3250	beta-galactosidase activity
DIU31_RS07700	COG0738	Major facilitator superfamily
DIU31_RS07705	COG1609	Transcriptional regulator
DIU31_RS07725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DIU31_RS07730	COG1309	transcriptional regulator
DIU31_RS07740	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DIU31_RS07765	COG0640	Transcriptional regulator
DIU31_RS07775	COG0517	IMP dehydrogenase activity
DIU31_RS07775	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DIU31_RS07780	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DIU31_RS07790	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DIU31_RS07805	COG4771	TonB-dependent receptor
DIU31_RS07810	COG0702	epimerase
DIU31_RS07845	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS07850	COG0302	gtp cyclohydrolase
DIU31_RS07865	COG1285	pathogenesis
DIU31_RS07870	COG3408	Glycogen debranching enzyme
DIU31_RS07875	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DIU31_RS07885	COG0438	transferase activity, transferring glycosyl groups
DIU31_RS07900	COG1216	Glycosyl transferase, family 2
DIU31_RS07910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DIU31_RS07915	COG0110	maltose O-acetyltransferase activity
DIU31_RS07920	COG0110	maltose O-acetyltransferase activity
DIU31_RS07950	COG4771	TonB-dependent receptor
DIU31_RS07955	COG0702	epimerase
DIU31_RS07970	COG4771	TonB-dependent receptor
DIU31_RS08045	COG3250	beta-galactosidase activity
DIU31_RS08065	COG4771	TonB-dependent receptor
DIU31_RS08070	COG2207	Transcriptional regulator
DIU31_RS08075	COG2824	Alkylphosphonate utilization operon protein PhnA
DIU31_RS08080	COG0352	thiamine-phosphate diphosphorylase activity
DIU31_RS08080	COG0351	phosphomethylpyrimidine kinase
DIU31_RS08085	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DIU31_RS08090	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DIU31_RS08095	COG2022	thiamine diphosphate biosynthetic process
DIU31_RS08100	COG0352	thiamine-phosphate diphosphorylase activity
DIU31_RS08110	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DIU31_RS08115	COG2104	thiamine diphosphate biosynthetic process
DIU31_RS08140	COG1278	Cold shock
DIU31_RS08145	COG1278	Cold shock
DIU31_RS08180	COG3507	Belongs to the glycosyl hydrolase 43 family
DIU31_RS08195	COG3693	PFAM glycoside hydrolase, family 10
DIU31_RS08195	COG3507	Belongs to the glycosyl hydrolase 43 family
DIU31_RS08195	COG2382	esterase
DIU31_RS08205	COG3693	PFAM glycoside hydrolase, family 10
DIU31_RS08205	COG2382	esterase
DIU31_RS08210	COG3292	Two component regulator propeller
DIU31_RS08210	COG2205	protein histidine kinase activity
DIU31_RS08210	COG0745	RESPONSE REGULATOR receiver
DIU31_RS08215	COG2382	esterase
DIU31_RS08220	COG4771	TonB-dependent receptor
DIU31_RS08245	COG3848	Pyruvate phosphate dikinase
DIU31_RS08245	COG0574	Belongs to the PEP-utilizing enzyme family
DIU31_RS08280	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DIU31_RS08310	COG1070	Carbohydrate kinase
DIU31_RS08315	COG2207	Transcriptional regulator
DIU31_RS08315	COG4753	response regulator
DIU31_RS08325	COG4948	Mandelate Racemase Muconate Lactonizing
DIU31_RS08330	COG0385	Bile acid
DIU31_RS08340	COG0129	dihydroxy-acid dehydratase activity
DIU31_RS08345	COG2610	gluconate transmembrane transporter activity
DIU31_RS08350	COG4206	TonB-dependent receptor
DIU31_RS08350	COG1629	transport
DIU31_RS08370	COG0659	secondary active sulfate transmembrane transporter activity
DIU31_RS08385	COG0509	glycine decarboxylation via glycine cleavage system
DIU31_RS08400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DIU31_RS08410	COG1881	PFAM PEBP family protein
DIU31_RS08425	COG1136	(ABC) transporter
DIU31_RS08445	COG1914	H( )-stimulated, divalent metal cation uptake system
DIU31_RS08450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DIU31_RS08470	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS08480	COG1127	ABC transporter
DIU31_RS08485	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DIU31_RS08490	COG0574	Belongs to the PEP-utilizing enzyme family
DIU31_RS08490	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DIU31_RS08495	COG0071	Belongs to the small heat shock protein (HSP20) family
DIU31_RS08500	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DIU31_RS08510	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DIU31_RS08530	COG0745	RESPONSE REGULATOR receiver
DIU31_RS08535	COG5002	protein histidine kinase activity
DIU31_RS08550	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DIU31_RS08570	COG0628	permease
DIU31_RS08585	COG1063	alcohol dehydrogenase
DIU31_RS08595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DIU31_RS08625	COG0745	RESPONSE REGULATOR receiver
DIU31_RS08630	COG5002	protein histidine kinase activity
DIU31_RS08640	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DIU31_RS08665	COG1611	Belongs to the LOG family
DIU31_RS08670	COG2205	protein histidine kinase activity
DIU31_RS08690	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
DIU31_RS08705	COG2205	protein histidine kinase activity
DIU31_RS08705	COG0784	Response regulator, receiver
DIU31_RS08755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DIU31_RS08785	COG0058	SHG alpha-glucan phosphorylase activity
DIU31_RS08805	COG4771	TonB-dependent receptor
DIU31_RS08825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DIU31_RS08835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DIU31_RS08840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DIU31_RS08875	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
DIU31_RS08925	COG0436	Aminotransferase
DIU31_RS08950	COG2989	Protein conserved in bacteria
DIU31_RS08955	COG4124	Belongs to the glycosyl hydrolase 26 family
DIU31_RS08975	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DIU31_RS08985	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DIU31_RS09005	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DIU31_RS09055	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DIU31_RS09075	COG3781	membrane
DIU31_RS09080	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DIU31_RS09105	COG0750	zinc metalloprotease
DIU31_RS09135	COG2217	Heavy metal translocating P-type atpase
DIU31_RS09315	COG0587	DNA-directed DNA polymerase activity
DIU31_RS09320	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DIU31_RS09335	COG1801	Protein of unknown function DUF72
DIU31_RS09345	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DIU31_RS09400	COG4771	TonB-dependent receptor
DIU31_RS09495	COG2815	serine threonine protein kinase
DIU31_RS09495	COG0515	serine threonine protein kinase
DIU31_RS09500	COG3593	DNA synthesis involved in DNA repair
DIU31_RS09505	COG1074	ATP-dependent DNA helicase activity
DIU31_RS09540	COG0028	Belongs to the TPP enzyme family
DIU31_RS09585	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS09610	COG3059	membrane
DIU31_RS09630	COG3604	Transcriptional regulator
DIU31_RS09635	COG3604	Transcriptional regulator
DIU31_RS09640	COG2814	Major facilitator Superfamily
DIU31_RS09670	COG0300	oxidoreductase activity
DIU31_RS09675	COG1309	transcriptional regulator
DIU31_RS09710	COG4771	TonB-dependent receptor
DIU31_RS09715	COG0702	epimerase
DIU31_RS09740	COG0745	RESPONSE REGULATOR receiver
DIU31_RS09740	COG2205	protein histidine kinase activity
DIU31_RS09740	COG3292	Two component regulator propeller
DIU31_RS09790	COG0582	viral genome integration into host DNA
DIU31_RS09830	COG1648	precorrin-2 dehydrogenase activity
DIU31_RS09830	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DIU31_RS09835	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DIU31_RS09840	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DIU31_RS09840	COG2146	nitrite reductase [NAD(P)H] activity
DIU31_RS09850	COG2223	nitrite transmembrane transporter activity
DIU31_RS09855	COG0243	molybdopterin cofactor binding
DIU31_RS09880	COG4771	TonB-dependent receptor
DIU31_RS09920	COG4771	TonB-dependent receptor
DIU31_RS09925	COG0702	epimerase
DIU31_RS09930	COG2755	lipolytic protein G-D-S-L family
DIU31_RS09940	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DIU31_RS09970	COG0579	oxidoreductase
DIU31_RS09980	COG4999	Histidine kinase
DIU31_RS09980	COG3437	response regulator, receiver
DIU31_RS09980	COG2205	protein histidine kinase activity
DIU31_RS09980	COG3850	Histidine kinase
DIU31_RS09985	COG4628	conserved protein (DUF2132)
DIU31_RS09990	COG0513	Belongs to the DEAD box helicase family
DIU31_RS09995	COG0101	tRNA pseudouridine synthase activity
DIU31_RS10010	COG0667	Aldo Keto reductase
DIU31_RS10040	COG1271	oxidase subunit
DIU31_RS10045	COG1609	Transcriptional regulator
DIU31_RS10050	COG1070	Carbohydrate kinase
DIU31_RS10055	COG2115	Belongs to the xylose isomerase family
DIU31_RS10065	COG1904	glucuronate isomerase
DIU31_RS10080	COG2271	Major facilitator Superfamily
DIU31_RS10090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DIU31_RS10095	COG3530	Putative quorum-sensing-regulated virulence factor
DIU31_RS10100	COG0598	Magnesium transport protein CorA
DIU31_RS10115	COG1215	transferase activity, transferring glycosyl groups
DIU31_RS10120	COG3264	Mechanosensitive ion channel
DIU31_RS10120	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
DIU31_RS10125	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DIU31_RS10130	COG4974	Belongs to the 'phage' integrase family
DIU31_RS10135	COG0824	Thioesterase
DIU31_RS10155	COG0647	UMP catabolic process
DIU31_RS10165	COG1584	GPR1 FUN34 yaaH family protein
DIU31_RS10170	COG0588	phosphoglycerate mutase activity
DIU31_RS10195	COG0612	Peptidase, M16
DIU31_RS10205	COG0517	IMP dehydrogenase activity
DIU31_RS10205	COG0516	GMP reductase activity
DIU31_RS10220	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DIU31_RS10230	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DIU31_RS10235	COG0492	ferredoxin-NADP+ reductase activity
DIU31_RS10250	COG0667	Aldo Keto reductase
DIU31_RS10265	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DIU31_RS10285	COG0750	zinc metalloprotease
DIU31_RS10290	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DIU31_RS10305	COG1216	Glycosyl transferase, family 2
DIU31_RS10305	COG0463	Glycosyl transferase, family 2
DIU31_RS10310	COG0463	Glycosyl transferase, family 2
DIU31_RS10320	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DIU31_RS10325	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DIU31_RS10330	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DIU31_RS10335	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DIU31_RS10355	COG4206	TonB-dependent receptor
DIU31_RS10365	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DIU31_RS10385	COG1956	GAF domain-containing protein
DIU31_RS10395	COG2094	Belongs to the DNA glycosylase MPG family
DIU31_RS10400	COG3844	kynureninase activity
DIU31_RS10405	COG3781	membrane
DIU31_RS10410	COG0123	including yeast histone deacetylase and acetoin utilization protein
DIU31_RS10415	COG0534	Mate efflux family protein
DIU31_RS10440	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS10470	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DIU31_RS10480	COG0408	coproporphyrinogen oxidase activity
DIU31_RS10485	COG2814	Major facilitator Superfamily
DIU31_RS10490	COG1278	Cold shock
DIU31_RS10495	COG0450	alkyl hydroperoxide reductase
DIU31_RS10500	COG3387	PFAM Glycoside hydrolase 15-related
DIU31_RS10505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DIU31_RS10510	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DIU31_RS10520	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS10530	COG0406	alpha-ribazole phosphatase activity
DIU31_RS10535	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DIU31_RS10545	COG0626	cystathionine gamma-synthase activity
DIU31_RS10550	COG1629	transport
DIU31_RS10555	COG2873	o-acetylhomoserine
DIU31_RS10560	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DIU31_RS10565	COG0460	homoserine dehydrogenase
DIU31_RS10570	COG0542	response to heat
DIU31_RS10580	COG5002	protein histidine kinase activity
DIU31_RS10590	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DIU31_RS10615	COG0494	nUDIX hydrolase
DIU31_RS10620	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DIU31_RS10630	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DIU31_RS10640	COG0488	(ABC) transporter
DIU31_RS10655	COG1309	transcriptional regulator
DIU31_RS10660	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DIU31_RS10675	COG0577	efflux transmembrane transporter activity
DIU31_RS10715	COG0163	prenyltransferase activity
DIU31_RS10725	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DIU31_RS10730	COG1666	GTP binding
DIU31_RS10735	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DIU31_RS10740	COG2239	Acts as a magnesium transporter
DIU31_RS10745	COG1739	Uncharacterized protein family UPF0029
DIU31_RS10750	COG0697	spore germination
DIU31_RS10755	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DIU31_RS10755	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DIU31_RS10760	COG2890	protein-(glutamine-N5) methyltransferase activity
DIU31_RS10770	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DIU31_RS10775	COG1181	Belongs to the D-alanine--D-alanine ligase family
DIU31_RS10795	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DIU31_RS10805	COG1295	ribonuclease BN
DIU31_RS10815	COG4974	Belongs to the 'phage' integrase family
DIU31_RS10855	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DIU31_RS10895	COG0702	epimerase
DIU31_RS10900	COG1629	transport
DIU31_RS10900	COG4206	TonB-dependent receptor
DIU31_RS10920	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DIU31_RS10955	COG2169	Transcriptional regulator
DIU31_RS10960	COG1166	arginine decarboxylase activity
DIU31_RS10990	COG1132	(ABC) transporter
DIU31_RS10995	COG1132	(ABC) transporter
DIU31_RS11005	COG4181	ATPase activity
DIU31_RS11035	COG0251	oxidation-reduction process
DIU31_RS11070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DIU31_RS11075	COG1522	sequence-specific DNA binding
DIU31_RS11090	COG2814	Major facilitator Superfamily
DIU31_RS11110	COG4771	TonB-dependent receptor
DIU31_RS11130	COG5002	protein histidine kinase activity
DIU31_RS11130	COG0784	Response regulator, receiver
DIU31_RS11130	COG2205	protein histidine kinase activity
DIU31_RS11140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DIU31_RS11145	COG0477	Major facilitator Superfamily
DIU31_RS11170	COG0456	acetyltransferase
DIU31_RS11190	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DIU31_RS11205	COG5002	protein histidine kinase activity
DIU31_RS11210	COG4251	negative regulation of phosphorylation
DIU31_RS11215	COG4251	negative regulation of phosphorylation
DIU31_RS11220	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
DIU31_RS11225	COG5002	protein histidine kinase activity
DIU31_RS11265	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DIU31_RS11295	COG2322	membrane
DIU31_RS11305	COG4221	oxidoreductase activity
DIU31_RS11350	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS11355	COG0071	Belongs to the small heat shock protein (HSP20) family
DIU31_RS11365	COG0277	FAD linked oxidase domain protein
DIU31_RS11375	COG1960	acyl-CoA dehydrogenase activity
DIU31_RS11380	COG2205	protein histidine kinase activity
DIU31_RS11385	COG2205	protein histidine kinase activity
DIU31_RS11390	COG2723	6-phospho-beta-galactosidase activity
DIU31_RS11405	COG1999	signal sequence binding
DIU31_RS11445	COG0481	GTPase activity
DIU31_RS11450	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DIU31_RS11470	COG0602	queuosine metabolic process
DIU31_RS11475	COG2885	chlorophyll binding
DIU31_RS11480	COG0514	ATP-dependent DNA helicase (RecQ)
DIU31_RS11490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DIU31_RS11495	COG0305	Participates in initiation and elongation during chromosome replication
DIU31_RS11510	COG2086	electron transfer activity
DIU31_RS11515	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DIU31_RS11525	COG2211	Major facilitator Superfamily
DIU31_RS11545	COG1959	2 iron, 2 sulfur cluster binding
DIU31_RS11550	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DIU31_RS11560	COG0730	response to heat
DIU31_RS11565	COG0175	sulfate reduction
DIU31_RS11575	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DIU31_RS11580	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DIU31_RS11585	COG0482	sulfurtransferase activity
DIU31_RS11605	COG3291	Pkd domain containing protein
DIU31_RS11620	COG0577	efflux transmembrane transporter activity
DIU31_RS11620	COG1136	(ABC) transporter
DIU31_RS11625	COG0577	efflux transmembrane transporter activity
DIU31_RS11625	COG1136	(ABC) transporter
DIU31_RS11630	COG0577	efflux transmembrane transporter activity
DIU31_RS11630	COG1136	(ABC) transporter
DIU31_RS11640	COG1136	(ABC) transporter
DIU31_RS11640	COG0577	efflux transmembrane transporter activity
DIU31_RS11650	COG0577	efflux transmembrane transporter activity
DIU31_RS11660	COG0577	efflux transmembrane transporter activity
DIU31_RS11665	COG0577	efflux transmembrane transporter activity
DIU31_RS11670	COG0577	efflux transmembrane transporter activity
DIU31_RS11705	COG0577	efflux transmembrane transporter activity
DIU31_RS11705	COG1136	(ABC) transporter
DIU31_RS11710	COG1136	(ABC) transporter
DIU31_RS11710	COG0577	efflux transmembrane transporter activity
DIU31_RS11715	COG1136	(ABC) transporter
DIU31_RS11730	COG3852	Histidine kinase
DIU31_RS11740	COG3132	Protein of unknown function, DUF480
DIU31_RS11745	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DIU31_RS11765	COG1741	Belongs to the pirin family
DIU31_RS11770	COG2855	membrane
DIU31_RS11800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DIU31_RS11815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DIU31_RS11825	COG2272	Belongs to the type-B carboxylesterase lipase family
DIU31_RS11830	COG2382	esterase
DIU31_RS11850	COG1765	OsmC-like protein
DIU31_RS11865	COG0700	Nucleoside recognition
DIU31_RS11920	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DIU31_RS11930	COG0483	inositol monophosphate 1-phosphatase activity
DIU31_RS11945	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DIU31_RS11965	COG0247	lactate metabolic process
DIU31_RS11970	COG2270	Major facilitator Superfamily
DIU31_RS11975	COG1742	UPF0060 membrane protein
DIU31_RS11990	COG2270	Major facilitator Superfamily
DIU31_RS12000	COG0028	Belongs to the TPP enzyme family
DIU31_RS12005	COG4771	TonB-dependent receptor
DIU31_RS12020	COG1131	(ABC) transporter
DIU31_RS12055	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
DIU31_RS12090	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DIU31_RS12095	COG0280	phosphate acetyltransferase
DIU31_RS12095	COG0857	belongs to the CobB CobQ family
DIU31_RS12125	COG2217	Heavy metal translocating P-type atpase
DIU31_RS12135	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DIU31_RS12145	COG0702	epimerase
DIU31_RS12150	COG4771	TonB-dependent receptor
DIU31_RS12175	COG1215	transferase activity, transferring glycosyl groups
DIU31_RS12185	COG3546	catalase activity
DIU31_RS12190	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS12200	COG1501	Belongs to the glycosyl hydrolase 31 family
DIU31_RS12225	COG2755	lipolytic protein G-D-S-L family
DIU31_RS12245	COG4206	TonB-dependent receptor
DIU31_RS12245	COG1629	transport
DIU31_RS12260	COG2755	lipolytic protein G-D-S-L family
DIU31_RS12295	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DIU31_RS12315	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
DIU31_RS12320	COG1058	Belongs to the CinA family
DIU31_RS12320	COG1546	Belongs to the CinA family
DIU31_RS12345	COG0745	RESPONSE REGULATOR receiver
DIU31_RS12360	COG3920	Histidine kinase
DIU31_RS12365	COG5002	protein histidine kinase activity
DIU31_RS12375	COG2267	carboxylic ester hydrolase activity
DIU31_RS12395	COG4249	Peptidase C14 caspase catalytic subunit p20
DIU31_RS12395	COG2319	Wd-40 repeat
DIU31_RS12415	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DIU31_RS12450	COG0346	lactoylglutathione lyase activity
DIU31_RS12455	COG0745	RESPONSE REGULATOR receiver
DIU31_RS12460	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DIU31_RS12480	COG0110	maltose O-acetyltransferase activity
DIU31_RS12490	COG0438	transferase activity, transferring glycosyl groups
DIU31_RS12505	COG1366	Belongs to the anti-sigma-factor antagonist family
DIU31_RS12510	COG0745	RESPONSE REGULATOR receiver
DIU31_RS12520	COG1215	transferase activity, transferring glycosyl groups
DIU31_RS12535	COG4953	penicillin-binding protein 1C
DIU31_RS12550	COG0557	exoribonuclease II activity
DIU31_RS12580	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DIU31_RS12585	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DIU31_RS12595	COG1301	dicarboxylic acid transport
DIU31_RS12605	COG1595	DNA-templated transcription, initiation
DIU31_RS12635	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DIU31_RS12650	COG2852	Protein conserved in bacteria
DIU31_RS12670	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DIU31_RS12680	COG0477	Major facilitator Superfamily
DIU31_RS12700	COG1012	belongs to the aldehyde dehydrogenase family
DIU31_RS12720	COG4771	TonB-dependent receptor
DIU31_RS12745	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DIU31_RS12805	COG0438	transferase activity, transferring glycosyl groups
DIU31_RS12805	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DIU31_RS12820	COG1216	Glycosyl transferase, family 2
DIU31_RS12850	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DIU31_RS12905	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DIU31_RS12920	COG2860	membrane
DIU31_RS12925	COG3537	Alpha-1,2-mannosidase
DIU31_RS12930	COG0702	epimerase
DIU31_RS12935	COG4771	TonB-dependent receptor
DIU31_RS12970	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
DIU31_RS13000	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DIU31_RS13005	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DIU31_RS13010	COG2081	HI0933 family
DIU31_RS13025	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DIU31_RS13035	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DIU31_RS13040	COG1678	Uncharacterized ACR, COG1678
DIU31_RS13045	COG0259	pyridoxamine-phosphate oxidase activity
DIU31_RS13050	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DIU31_RS13055	COG0649	NAD binding
DIU31_RS13060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DIU31_RS13095	COG1119	ATPase activity
DIU31_RS13100	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
DIU31_RS13105	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DIU31_RS13130	COG2910	NAD(P)H-binding
DIU31_RS13135	COG2264	protein methyltransferase activity
DIU31_RS13145	COG0149	triose-phosphate isomerase activity
DIU31_RS13155	COG0254	rRNA binding
DIU31_RS13160	COG0346	lactoylglutathione lyase activity
DIU31_RS13165	COG1104	cysteine desulfurase activity
DIU31_RS13170	COG0822	iron-sulfur transferase activity
DIU31_RS13175	COG0316	Belongs to the HesB IscA family
DIU31_RS13190	COG1022	Amp-dependent synthetase and ligase
DIU31_RS13205	COG2201	protein-glutamate methylesterase activity
DIU31_RS13210	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
DIU31_RS13225	COG2267	carboxylic ester hydrolase activity
DIU31_RS13250	COG1538	Outer membrane efflux protein
DIU31_RS13290	COG1185	polyribonucleotide nucleotidyltransferase activity
DIU31_RS13295	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DIU31_RS13305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DIU31_RS13310	COG1940	carbohydrate kinase activity
DIU31_RS13320	COG0628	permease
DIU31_RS13360	COG0702	epimerase
DIU31_RS13365	COG4771	TonB-dependent receptor
DIU31_RS13370	COG0673	inositol 2-dehydrogenase activity
DIU31_RS13380	COG1609	Transcriptional regulator
DIU31_RS13400	COG0708	Exodeoxyribonuclease III
DIU31_RS13410	COG1131	(ABC) transporter
DIU31_RS13420	COG1725	Transcriptional regulator
DIU31_RS13430	COG1131	(ABC) transporter
DIU31_RS13450	COG1629	transport
DIU31_RS13465	COG1609	Transcriptional regulator
DIU31_RS13470	COG1349	DNA-binding transcription factor activity
DIU31_RS13480	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DIU31_RS13485	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DIU31_RS13495	COG0702	epimerase
DIU31_RS13500	COG4771	TonB-dependent receptor
DIU31_RS13515	COG2186	Transcriptional regulator
DIU31_RS13520	COG2223	nitrite transmembrane transporter activity
DIU31_RS13550	COG4771	TonB-dependent receptor
DIU31_RS13570	COG3588	fructose-bisphosphate aldolase
DIU31_RS13575	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DIU31_RS13610	COG0277	FAD linked oxidase domain protein
DIU31_RS13635	COG1595	DNA-templated transcription, initiation
DIU31_RS13645	COG1312	Catalyzes the dehydration of D-mannonate
DIU31_RS13655	COG4191	Histidine kinase
DIU31_RS13660	COG2204	response regulator
DIU31_RS13670	COG1136	(ABC) transporter
DIU31_RS13670	COG0577	efflux transmembrane transporter activity
DIU31_RS13675	COG1136	(ABC) transporter
DIU31_RS13695	COG0784	Response regulator, receiver
DIU31_RS13695	COG2205	protein histidine kinase activity
DIU31_RS13695	COG5002	protein histidine kinase activity
DIU31_RS13715	COG2211	Major facilitator Superfamily
DIU31_RS13735	COG0673	inositol 2-dehydrogenase activity
DIU31_RS13770	COG0823	Involved in the tonB-independent uptake of proteins
DIU31_RS13780	COG2205	protein histidine kinase activity
DIU31_RS13785	COG1607	acyl-coa hydrolase
DIU31_RS13800	COG1047	Peptidyl-prolyl cis-trans
DIU31_RS13805	COG1331	Highly conserved protein containing a thioredoxin domain
DIU31_RS13815	COG0745	RESPONSE REGULATOR receiver
DIU31_RS13830	COG0210	DNA helicase
DIU31_RS13835	COG3620	sequence-specific DNA binding
DIU31_RS13855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DIU31_RS13865	COG4948	Mandelate Racemase Muconate Lactonizing
DIU31_RS13875	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DIU31_RS13895	COG4771	TonB-dependent receptor
DIU31_RS13900	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DIU31_RS13905	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DIU31_RS13915	COG0544	peptidyl-prolyl cis-trans isomerase activity
DIU31_RS13940	COG0640	Transcriptional regulator
DIU31_RS13950	COG0514	ATP-dependent DNA helicase (RecQ)
DIU31_RS13955	COG2819	hydrolase of the alpha beta superfamily
DIU31_RS13960	COG1629	transport
DIU31_RS13960	COG4206	TonB-dependent receptor
DIU31_RS13980	COG5002	protein histidine kinase activity
DIU31_RS13980	COG0784	Response regulator, receiver
DIU31_RS13990	COG1136	(ABC) transporter
DIU31_RS13990	COG0577	efflux transmembrane transporter activity
DIU31_RS13995	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DIU31_RS14000	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DIU31_RS14040	COG1136	(ABC) transporter
DIU31_RS14045	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DIU31_RS14055	COG0180	Tryptophanyl-tRNA synthetase
DIU31_RS14060	COG1428	Deoxynucleoside kinase
DIU31_RS14070	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DIU31_RS14080	COG0504	CTP synthase activity
DIU31_RS14085	COG0706	membrane insertase activity
DIU31_RS14090	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DIU31_RS14090	COG1199	ATP-dependent helicase activity
DIU31_RS14100	COG0823	Involved in the tonB-independent uptake of proteins
DIU31_RS14105	COG0823	Involved in the tonB-independent uptake of proteins
DIU31_RS14105	COG1506	peptidase
DIU31_RS14115	COG4152	abc transporter atp-binding protein
DIU31_RS14120	COG1668	transmembrane transport
DIU31_RS14125	COG0248	Ppx GppA phosphatase
DIU31_RS14140	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DIU31_RS14165	COG0424	maF-like protein
DIU31_RS14170	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DIU31_RS14180	COG0633	Ferredoxin
DIU31_RS14215	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DIU31_RS14250	COG0784	Response regulator, receiver
DIU31_RS14250	COG2205	protein histidine kinase activity
DIU31_RS14260	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DIU31_RS14265	COG0784	Response regulator, receiver
DIU31_RS14265	COG2205	protein histidine kinase activity
DIU31_RS14285	COG0513	Belongs to the DEAD box helicase family
DIU31_RS14295	COG1733	regulation of RNA biosynthetic process
DIU31_RS14305	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DIU31_RS14320	COG1673	EVE domain
DIU31_RS14325	COG2378	regulation of single-species biofilm formation
DIU31_RS14335	COG1446	asparaginase
DIU31_RS14340	COG3142	Participates in the control of copper homeostasis
DIU31_RS14410	COG1522	sequence-specific DNA binding
DIU31_RS14415	COG0697	spore germination
DIU31_RS14445	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
DIU31_RS14455	COG1690	Belongs to the RtcB family
DIU31_RS14485	COG1051	belongs to the nudix hydrolase family
DIU31_RS14550	COG3541	Predicted nucleotidyltransferase
DIU31_RS14560	COG3537	Alpha-1,2-mannosidase
DIU31_RS14570	COG1609	Transcriptional regulator
DIU31_RS14580	COG0626	cystathionine gamma-synthase activity
DIU31_RS14585	COG3604	Transcriptional regulator
DIU31_RS14685	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DIU31_RS14715	COG3507	Belongs to the glycosyl hydrolase 43 family
DIU31_RS14720	COG4977	sequence-specific DNA binding
DIU31_RS14725	COG4948	Mandelate Racemase Muconate Lactonizing
DIU31_RS14745	COG4771	TonB-dependent receptor
DIU31_RS14780	COG2207	Transcriptional regulator
DIU31_RS14790	COG2197	response regulator
DIU31_RS14805	COG5002	protein histidine kinase activity
DIU31_RS14820	COG1752	Esterase of the alpha-beta hydrolase superfamily
DIU31_RS14850	COG3507	Belongs to the glycosyl hydrolase 43 family
DIU31_RS14855	COG0702	epimerase
DIU31_RS14860	COG4771	TonB-dependent receptor
DIU31_RS14875	COG0667	Aldo Keto reductase
DIU31_RS14890	COG0501	Belongs to the peptidase M48B family
DIU31_RS14910	COG3552	Protein containing von Willebrand factor type A (VWA) domain
DIU31_RS14915	COG2425	protein containing a von Willebrand factor type A (vWA) domain
DIU31_RS14920	COG0714	Associated with various cellular activities
DIU31_RS14940	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DIU31_RS14945	COG1064	alcohol dehydrogenase
DIU31_RS14955	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS14975	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DIU31_RS14980	COG1607	acyl-coa hydrolase
DIU31_RS14985	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DIU31_RS14990	COG0460	homoserine dehydrogenase
DIU31_RS14990	COG0527	aspartate kinase activity
DIU31_RS15000	COG0456	acetyltransferase
DIU31_RS15005	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DIU31_RS15015	COG1193	negative regulation of DNA recombination
DIU31_RS15025	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DIU31_RS15025	COG2755	lipolytic protein G-D-S-L family
DIU31_RS15035	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DIU31_RS15055	COG3942	CHAP domain
DIU31_RS15055	COG1388	LysM domain
DIU31_RS15065	COG0783	Belongs to the Dps family
DIU31_RS15075	COG0577	efflux transmembrane transporter activity
DIU31_RS15090	COG0561	phosphatase activity
DIU31_RS15095	COG1629	transport
DIU31_RS15105	COG1595	DNA-templated transcription, initiation
DIU31_RS15120	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS15170	COG0702	epimerase
DIU31_RS15175	COG4771	TonB-dependent receptor
DIU31_RS15185	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DIU31_RS15215	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS15225	COG1022	Amp-dependent synthetase and ligase
DIU31_RS15230	COG0183	Belongs to the thiolase family
DIU31_RS15235	COG1024	Enoyl-CoA hydratase
DIU31_RS15235	COG1250	3-hydroxyacyl-CoA dehydrogenase
DIU31_RS15255	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DIU31_RS15265	COG1960	acyl-CoA dehydrogenase activity
DIU31_RS15290	COG1752	Esterase of the alpha-beta hydrolase superfamily
DIU31_RS15300	COG0671	phosphoesterase, PA-phosphatase related
DIU31_RS15325	COG3757	hydrolase, family 25
DIU31_RS15335	COG1733	regulation of RNA biosynthetic process
DIU31_RS15345	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DIU31_RS15350	COG0668	transmembrane transport
DIU31_RS15375	COG3279	Response regulator of the LytR AlgR family
DIU31_RS15410	COG0860	N-Acetylmuramoyl-L-alanine amidase
DIU31_RS15455	COG1309	transcriptional regulator
DIU31_RS15515	COG0724	RNA recognition motif
DIU31_RS15755	COG4771	TonB-dependent receptor
DIU31_RS15805	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DIU31_RS15820	COG0798	PFAM Bile acid sodium symporter
DIU31_RS15835	COG1742	UPF0060 membrane protein
DIU31_RS15900	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DIU31_RS15905	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DIU31_RS15920	COG2217	Heavy metal translocating P-type atpase
DIU31_RS15935	COG2217	Heavy metal translocating P-type atpase
DIU31_RS16085	COG4942	peptidase
DIU31_RS16125	COG0724	RNA recognition motif
DIU31_RS16140	COG0587	DNA-directed DNA polymerase activity
DIU31_RS16190	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DIU31_RS16215	COG4977	sequence-specific DNA binding
DIU31_RS16215	COG1917	Cupin 2, conserved barrel domain protein
DIU31_RS16220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DIU31_RS16225	COG1902	pentaerythritol trinitrate reductase activity
DIU31_RS16230	COG0640	Transcriptional regulator
DIU31_RS16240	COG1917	Cupin 2, conserved barrel domain protein
DIU31_RS16240	COG4977	sequence-specific DNA binding
DIU31_RS16310	COG3285	dna ligase
DIU31_RS16310	COG1793	dna ligase
DIU31_RS16370	COG1570	exodeoxyribonuclease VII activity
DIU31_RS16445	COG4372	Transposase
DIU31_RS16505	COG2267	carboxylic ester hydrolase activity
DIU31_RS16515	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS16530	COG1064	alcohol dehydrogenase
DIU31_RS16540	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS16545	COG1063	alcohol dehydrogenase
DIU31_RS16555	COG5002	protein histidine kinase activity
DIU31_RS16560	COG5002	protein histidine kinase activity
DIU31_RS16625	COG1864	DNA RNA non-specific endonuclease
DIU31_RS16625	COG3591	Belongs to the peptidase S1B family
DIU31_RS16630	COG1609	Transcriptional regulator
DIU31_RS16635	COG3537	Alpha-1,2-mannosidase
DIU31_RS16655	COG0702	epimerase
DIU31_RS16660	COG4206	TonB-dependent receptor
DIU31_RS16660	COG1629	transport
DIU31_RS16680	COG3279	Response regulator of the LytR AlgR family
DIU31_RS16695	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DIU31_RS16700	COG1764	response to oxidative stress
DIU31_RS16720	COG2814	Major facilitator Superfamily
DIU31_RS16735	COG2373	Large extracellular alpha-helical protein
DIU31_RS16775	COG2010	Cytochrome c
DIU31_RS16785	COG1959	2 iron, 2 sulfur cluster binding
DIU31_RS16790	COG5002	protein histidine kinase activity
DIU31_RS16850	COG3940	Belongs to the glycosyl hydrolase 43 family
DIU31_RS16910	COG0667	Aldo Keto reductase
DIU31_RS16915	COG0673	inositol 2-dehydrogenase activity
DIU31_RS16920	COG0628	permease
DIU31_RS16955	COG1764	response to oxidative stress
DIU31_RS17000	COG2197	response regulator
DIU31_RS17015	COG0702	epimerase
DIU31_RS17020	COG4771	TonB-dependent receptor
DIU31_RS17035	COG4191	Histidine kinase
DIU31_RS17055	COG2027	D-alanyl-D-alanine carboxypeptidase
DIU31_RS17060	COG0531	amino acid
DIU31_RS17065	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DIU31_RS17070	COG3655	Transcriptional regulator
DIU31_RS17080	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DIU31_RS17085	COG5654	RES domain protein
DIU31_RS17095	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DIU31_RS17120	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DIU31_RS17125	COG0540	Belongs to the ATCase OTCase family
DIU31_RS17145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DIU31_RS17170	COG3250	beta-galactosidase activity
DIU31_RS17200	COG1629	transport
DIU31_RS17200	COG4206	TonB-dependent receptor
DIU31_RS17205	COG1472	Belongs to the glycosyl hydrolase 3 family
DIU31_RS17220	COG2205	protein histidine kinase activity
DIU31_RS17230	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DIU31_RS17240	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DIU31_RS17250	COG2204	response regulator
DIU31_RS17270	COG0577	efflux transmembrane transporter activity
DIU31_RS17285	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DIU31_RS17305	COG0366	Alpha amylase catalytic
DIU31_RS17315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DIU31_RS17320	COG0366	Alpha amylase catalytic
DIU31_RS17355	COG1525	nuclease
DIU31_RS17390	COG0045	succinate-CoA ligase (ADP-forming) activity
DIU31_RS17395	COG1136	(ABC) transporter
DIU31_RS17415	COG1196	nuclear chromosome segregation
DIU31_RS17435	COG1131	(ABC) transporter
DIU31_RS17465	COG2972	Histidine kinase
DIU31_RS17470	COG3279	Response regulator of the LytR AlgR family
DIU31_RS17485	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DIU31_RS17490	COG0019	diaminopimelate decarboxylase activity
DIU31_RS17495	COG4413	Urea transporter
DIU31_RS17525	COG0006	proline dipeptidase activity
DIU31_RS17535	COG3345	alpha-galactosidase
DIU31_RS17540	COG0531	amino acid
DIU31_RS17555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DIU31_RS17560	COG3938	Belongs to the proline racemase family
DIU31_RS17565	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DIU31_RS17575	COG1629	transport
DIU31_RS17575	COG4206	TonB-dependent receptor
DIU31_RS17610	COG3250	beta-galactosidase activity
DIU31_RS17615	COG5520	Belongs to the glycosyl hydrolase 30 family
DIU31_RS17625	COG0702	epimerase
DIU31_RS17630	COG1629	transport
DIU31_RS17635	COG3292	Two component regulator propeller
DIU31_RS17635	COG2205	protein histidine kinase activity
DIU31_RS17635	COG0745	RESPONSE REGULATOR receiver
DIU31_RS17640	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DIU31_RS17650	COG1629	transport
DIU31_RS17655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DIU31_RS17700	COG4771	TonB-dependent receptor
DIU31_RS17705	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
DIU31_RS17710	COG1454	alcohol dehydrogenase
DIU31_RS17715	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DIU31_RS17720	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DIU31_RS17725	COG3395	kinase activity
DIU31_RS17730	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DIU31_RS17750	COG3940	Belongs to the glycosyl hydrolase 43 family
DIU31_RS17760	COG3408	Glycogen debranching enzyme
DIU31_RS17805	COG3408	Glycogen debranching enzyme
DIU31_RS17810	COG3250	beta-galactosidase activity
DIU31_RS17845	COG0702	epimerase
DIU31_RS17850	COG4771	TonB-dependent receptor
DIU31_RS17865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DIU31_RS17870	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DIU31_RS17875	COG3250	beta-galactosidase activity
DIU31_RS17885	COG3408	Glycogen debranching enzyme
DIU31_RS17890	COG3250	beta-galactosidase activity
DIU31_RS17910	COG1063	alcohol dehydrogenase
DIU31_RS17915	COG2721	sulfolactate sulfo-lyase activity
DIU31_RS17920	COG0246	Mannitol dehydrogenase
DIU31_RS17925	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DIU31_RS17930	COG4677	pectinesterase activity
DIU31_RS17995	COG0542	response to heat
DIU31_RS18050	COG0442	prolyl-tRNA aminoacylation
DIU31_RS18055	COG0626	cystathionine gamma-synthase activity
DIU31_RS18080	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DIU31_RS18110	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS18115	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
DIU31_RS18120	COG2731	YhcH YjgK YiaL family protein
DIU31_RS18130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DIU31_RS18135	COG3537	Alpha-1,2-mannosidase
DIU31_RS18140	COG1472	Belongs to the glycosyl hydrolase 3 family
DIU31_RS18145	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DIU31_RS18155	COG3408	Glycogen debranching enzyme
DIU31_RS18160	COG0702	epimerase
DIU31_RS18165	COG4771	TonB-dependent receptor
DIU31_RS18185	COG0346	lactoylglutathione lyase activity
DIU31_RS18190	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DIU31_RS18210	COG0772	Belongs to the SEDS family
DIU31_RS18240	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DIU31_RS18255	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DIU31_RS18270	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DIU31_RS18285	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DIU31_RS18290	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DIU31_RS18320	COG1228	amidohydrolase
DIU31_RS18330	COG3158	transport of potassium into the cell
DIU31_RS18340	COG0004	ammonium transporteR
DIU31_RS18345	COG1007	ATP synthesis coupled electron transport
DIU31_RS18350	COG4771	TonB-dependent receptor
DIU31_RS18360	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DIU31_RS18365	COG0713	ATP synthesis coupled electron transport
DIU31_RS18375	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DIU31_RS18380	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DIU31_RS18385	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DIU31_RS18405	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DIU31_RS18410	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DIU31_RS18425	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DIU31_RS18445	COG1610	YqeY-like protein
DIU31_RS18450	COG4221	oxidoreductase activity
DIU31_RS18460	COG2226	methyltransferase
DIU31_RS18465	COG0673	inositol 2-dehydrogenase activity
DIU31_RS18475	COG2514	catechol 2,3-dioxygenase activity
DIU31_RS18480	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DIU31_RS18485	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DIU31_RS18510	COG0438	transferase activity, transferring glycosyl groups
DIU31_RS18515	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DIU31_RS18535	COG1595	DNA-templated transcription, initiation
DIU31_RS18540	COG3958	Transketolase
DIU31_RS18545	COG3959	Transketolase, thiamine diphosphate binding domain
DIU31_RS18550	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DIU31_RS18560	COG0179	Fumarylacetoacetate (FAA) hydrolase
DIU31_RS18570	COG3158	transport of potassium into the cell
DIU31_RS18580	COG0531	amino acid
DIU31_RS18580	COG0531	amino acid
DIU31_RS18595	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
DIU31_RS18600	COG0745	RESPONSE REGULATOR receiver
DIU31_RS18615	COG3118	belongs to the thioredoxin family
DIU31_RS18625	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS18630	COG1733	regulation of RNA biosynthetic process
DIU31_RS18660	COG2197	response regulator
DIU31_RS18680	COG1217	gtp-binding protein TYPA
DIU31_RS18710	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DIU31_RS18735	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DIU31_RS18745	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DIU31_RS18760	COG4771	TonB-dependent receptor
DIU31_RS18765	COG0511	ligase activity, forming carbon-carbon bonds
DIU31_RS18775	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DIU31_RS18780	COG1253	flavin adenine dinucleotide binding
DIU31_RS18790	COG0586	Pfam SNARE associated Golgi protein
DIU31_RS18795	COG1007	ATP synthesis coupled electron transport
DIU31_RS18800	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DIU31_RS18805	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DIU31_RS18810	COG0713	ATP synthesis coupled electron transport
DIU31_RS18815	COG0839	Belongs to the complex I subunit 6 family
DIU31_RS18820	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DIU31_RS18825	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DIU31_RS18830	COG1034	ATP synthesis coupled electron transport
DIU31_RS18840	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DIU31_RS18845	COG0649	NAD binding
DIU31_RS18850	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DIU31_RS18855	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DIU31_RS18860	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DIU31_RS18885	COG0848	biopolymer transport protein
DIU31_RS18895	COG0811	peptide transport
DIU31_RS18905	COG1597	lipid kinase activity
DIU31_RS18910	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DIU31_RS18940	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DIU31_RS18955	COG1242	4 iron, 4 sulfur cluster binding
DIU31_RS18980	COG1349	DNA-binding transcription factor activity
DIU31_RS18985	COG2814	Major facilitator Superfamily
DIU31_RS19005	COG1943	Transposase
DIU31_RS19015	COG0494	nUDIX hydrolase
DIU31_RS19055	COG0457	Tetratricopeptide repeat
DIU31_RS19060	COG2814	Major facilitator Superfamily
DIU31_RS19060	COG0477	Major facilitator Superfamily
DIU31_RS19080	COG3275	phosphorelay sensor kinase activity
DIU31_RS19085	COG3279	Response regulator of the LytR AlgR family
DIU31_RS19100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DIU31_RS19110	COG1104	cysteine desulfurase activity
DIU31_RS19115	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DIU31_RS19115	COG2207	Transcriptional regulator
DIU31_RS19120	COG3059	membrane
DIU31_RS19155	COG0673	inositol 2-dehydrogenase activity
DIU31_RS19165	COG0596	Alpha beta hydrolase
DIU31_RS19195	COG0582	viral genome integration into host DNA
DIU31_RS19245	COG4584	PFAM Integrase catalytic
DIU31_RS19250	COG1484	DNA-dependent DNA replication
DIU31_RS19315	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DIU31_RS19335	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DIU31_RS19335	COG2755	lipolytic protein G-D-S-L family
DIU31_RS19350	COG1960	acyl-CoA dehydrogenase activity
DIU31_RS19370	COG3292	Two component regulator propeller
DIU31_RS19370	COG2205	protein histidine kinase activity
DIU31_RS19370	COG0745	RESPONSE REGULATOR receiver
DIU31_RS19375	COG1609	Transcriptional regulator
DIU31_RS19380	COG1082	Xylose isomerase domain protein TIM barrel
DIU31_RS19400	COG3292	Two component regulator propeller
DIU31_RS19400	COG0745	RESPONSE REGULATOR receiver
DIU31_RS19400	COG2205	protein histidine kinase activity
DIU31_RS19405	COG4771	TonB-dependent receptor
DIU31_RS19420	COG3250	beta-galactosidase activity
DIU31_RS19475	COG1619	proteins homologs of microcin C7 resistance protein MccF
DIU31_RS19485	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DIU31_RS19490	COG2188	Transcriptional regulator
DIU31_RS19510	COG0693	protein deglycase activity
DIU31_RS19535	COG1598	PFAM Uncharacterised protein family UPF0150
DIU31_RS19540	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DIU31_RS19545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DIU31_RS19550	COG0217	transcriptional regulatory protein
DIU31_RS19585	COG0702	epimerase
DIU31_RS19590	COG1629	transport
DIU31_RS19600	COG1054	Belongs to the UPF0176 family
DIU31_RS19610	COG0156	8-amino-7-oxononanoate synthase activity
DIU31_RS19625	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DIU31_RS19645	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DIU31_RS19655	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DIU31_RS19660	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DIU31_RS19665	COG0601	transmembrane transport
DIU31_RS19680	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DIU31_RS19695	COG1137	ATPase activity
DIU31_RS19700	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DIU31_RS19700	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DIU31_RS19710	COG2201	protein-glutamate methylesterase activity
DIU31_RS19715	COG2329	Antibiotic biosynthesis monooxygenase
DIU31_RS19740	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DIU31_RS19765	COG1663	tetraacyldisaccharide 4'-kinase activity
DIU31_RS19770	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DIU31_RS19790	COG2972	Histidine kinase
DIU31_RS19790	COG0745	RESPONSE REGULATOR receiver
DIU31_RS19795	COG3279	Response regulator of the LytR AlgR family
DIU31_RS19815	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DIU31_RS19820	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DIU31_RS19850	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DIU31_RS19865	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DIU31_RS19875	COG1301	dicarboxylic acid transport
DIU31_RS19905	COG1363	Peptidase, m42
DIU31_RS19920	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DIU31_RS19935	COG0288	reversible hydration of carbon dioxide
DIU31_RS19945	COG0288	reversible hydration of carbon dioxide
DIU31_RS19950	COG1012	belongs to the aldehyde dehydrogenase family
DIU31_RS19980	COG0667	Aldo Keto reductase
DIU31_RS19995	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
DIU31_RS19995	COG3264	Mechanosensitive ion channel
DIU31_RS20035	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
DIU31_RS20055	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DIU31_RS20115	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DIU31_RS20120	COG1555	photosystem II stabilization
DIU31_RS20140	COG1418	mRNA catabolic process
DIU31_RS20160	COG2003	Belongs to the UPF0758 family
DIU31_RS20165	COG0268	Binds directly to 16S ribosomal RNA
DIU31_RS20175	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DIU31_RS20195	COG0586	Pfam SNARE associated Golgi protein
DIU31_RS20210	COG0592	DNA-directed DNA polymerase activity
DIU31_RS20240	COG4555	ABC transporter
DIU31_RS20255	COG0423	glycine-tRNA ligase activity
DIU31_RS20300	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DIU31_RS20355	COG0730	response to heat
DIU31_RS20365	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DIU31_RS20380	COG0156	8-amino-7-oxononanoate synthase activity
DIU31_RS20385	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DIU31_RS20400	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DIU31_RS20405	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DIU31_RS20410	COG0772	Belongs to the SEDS family
DIU31_RS20415	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DIU31_RS20420	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DIU31_RS20425	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DIU31_RS20440	COG0275	rRNA processing
DIU31_RS20445	COG2001	Belongs to the MraZ family
DIU31_RS20455	COG4774	siderophore transport
DIU31_RS20485	COG0126	phosphoglycerate kinase activity
DIU31_RS20495	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DIU31_RS20500	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DIU31_RS20525	COG0367	asparagine synthase
DIU31_RS20530	COG0438	transferase activity, transferring glycosyl groups
DIU31_RS20565	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS20570	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DIU31_RS20575	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DIU31_RS20590	COG1216	Glycosyl transferase, family 2
DIU31_RS20590	COG1442	glycosyl transferase family 8
DIU31_RS20600	COG0110	maltose O-acetyltransferase activity
DIU31_RS20605	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DIU31_RS20615	COG1216	Glycosyl transferase, family 2
DIU31_RS20625	COG1696	Membrane protein involved in D-alanine export
DIU31_RS20665	COG1215	transferase activity, transferring glycosyl groups
DIU31_RS20675	COG0297	glycogen (starch) synthase activity
DIU31_RS20720	COG0110	maltose O-acetyltransferase activity
DIU31_RS20730	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DIU31_RS20735	COG0563	adenylate kinase activity
DIU31_RS20750	COG3321	synthase
DIU31_RS20750	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS20750	COG0604	alcohol dehydrogenase
DIU31_RS20760	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DIU31_RS20765	COG0129	dihydroxy-acid dehydratase activity
DIU31_RS20770	COG0028	Belongs to the TPP enzyme family
DIU31_RS20775	COG0440	acetolactate synthase activity
DIU31_RS20780	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DIU31_RS20785	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DIU31_RS20795	COG0066	3-isopropylmalate dehydratase activity
DIU31_RS20805	COG0473	3-isopropylmalate dehydrogenase activity
DIU31_RS20810	COG4106	trans-aconitate 2-methyltransferase activity
DIU31_RS20815	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DIU31_RS20820	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DIU31_RS20825	COG0596	Alpha beta hydrolase
DIU31_RS20870	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DIU31_RS20875	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DIU31_RS20910	COG0747	negative chemotaxis
DIU31_RS20915	COG0508	dehydrogenase complex catalyzes the overall conversion of
DIU31_RS20925	COG0415	Belongs to the DNA photolyase family
DIU31_RS20930	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
DIU31_RS20935	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DIU31_RS20955	COG2249	NAD(P)H dehydrogenase (quinone) activity
DIU31_RS20975	COG3250	beta-galactosidase activity
DIU31_RS20980	COG0300	oxidoreductase activity
DIU31_RS21020	COG2204	response regulator
DIU31_RS21025	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DIU31_RS21050	COG0632	four-way junction helicase activity
DIU31_RS21055	COG0281	malic enzyme
DIU31_RS21055	COG0280	phosphate acetyltransferase
DIU31_RS21065	COG0741	lytic transglycosylase activity
DIU31_RS21065	COG1388	LysM domain
DIU31_RS21070	COG0154	amidase activity
DIU31_RS21075	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DIU31_RS21080	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DIU31_RS21100	COG0756	dUTP diphosphatase activity
DIU31_RS21110	COG1254	Belongs to the acylphosphatase family
DIU31_RS21125	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DIU31_RS21140	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DIU31_RS21155	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DIU31_RS21160	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DIU31_RS21170	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DIU31_RS21190	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DIU31_RS21205	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DIU31_RS21210	COG0047	phosphoribosylformylglycinamidine synthase activity
DIU31_RS21235	COG1011	Hydrolase
DIU31_RS21240	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DIU31_RS21255	COG0556	nucleotide-excision repair
DIU31_RS21275	COG1216	Glycosyl transferase, family 2
DIU31_RS21285	COG0823	Involved in the tonB-independent uptake of proteins
DIU31_RS21300	COG0363	glucosamine-6-phosphate deaminase activity
DIU31_RS21325	COG0738	Major facilitator superfamily
DIU31_RS21350	COG1741	Belongs to the pirin family
DIU31_RS21400	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DIU31_RS21400	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
DIU31_RS21410	COG1472	Belongs to the glycosyl hydrolase 3 family
DIU31_RS21420	COG0210	DNA helicase
DIU31_RS21425	COG1943	Transposase
DIU31_RS21430	COG2234	aminopeptidase activity
DIU31_RS21450	COG3275	phosphorelay sensor kinase activity
DIU31_RS21460	COG3279	Response regulator of the LytR AlgR family
DIU31_RS21465	COG4251	negative regulation of phosphorylation
DIU31_RS21470	COG0745	RESPONSE REGULATOR receiver
DIU31_RS21475	COG0745	RESPONSE REGULATOR receiver
DIU31_RS21485	COG1132	(ABC) transporter
DIU31_RS21490	COG0233	cytoplasmic translational termination
DIU31_RS21505	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DIU31_RS21525	COG4974	Belongs to the 'phage' integrase family
DIU31_RS21565	COG4974	Belongs to the 'phage' integrase family
DIU31_RS21595	COG5433	transposase activity
DIU31_RS21755	COG1629	transport
DIU31_RS21755	COG4206	TonB-dependent receptor
DIU31_RS21775	COG3046	protein related to deoxyribodipyrimidine photolyase
DIU31_RS21800	COG3661	Belongs to the glycosyl hydrolase 67 family
DIU31_RS21805	COG1312	Catalyzes the dehydration of D-mannonate
DIU31_RS21815	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS21915	COG2972	Histidine kinase
DIU31_RS21920	COG3279	Response regulator of the LytR AlgR family
DIU31_RS21925	COG0252	asparaginase activity
DIU31_RS21930	COG0084	hydrolase, TatD family'
DIU31_RS21935	COG0545	Peptidyl-prolyl cis-trans isomerase
DIU31_RS21945	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DIU31_RS21950	COG0105	UTP biosynthetic process
DIU31_RS21965	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DIU31_RS21975	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DIU31_RS21985	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DIU31_RS21990	COG1595	DNA-templated transcription, initiation
DIU31_RS22000	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DIU31_RS22000	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DIU31_RS22005	COG0583	DNA-binding transcription factor activity
DIU31_RS22025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DIU31_RS22030	COG0531	amino acid
DIU31_RS22040	COG0590	tRNA wobble adenosine to inosine editing
DIU31_RS22045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DIU31_RS22070	COG2205	protein histidine kinase activity
DIU31_RS22070	COG5002	protein histidine kinase activity
DIU31_RS22070	COG0784	Response regulator, receiver
DIU31_RS22090	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DIU31_RS22120	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DIU31_RS22125	COG4771	TonB-dependent receptor
DIU31_RS22190	COG4242	Belongs to the peptidase S51 family
DIU31_RS22195	COG1446	asparaginase
DIU31_RS22210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DIU31_RS22220	COG4221	oxidoreductase activity
DIU31_RS22225	COG4221	oxidoreductase activity
DIU31_RS22230	COG4221	oxidoreductase activity
DIU31_RS22260	COG0640	Transcriptional regulator
DIU31_RS22275	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DIU31_RS22285	COG0798	PFAM Bile acid sodium symporter
DIU31_RS22340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DIU31_RS22355	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DIU31_RS22400	COG2217	Heavy metal translocating P-type atpase
DIU31_RS22405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DIU31_RS22410	COG2132	Multicopper oxidase
DIU31_RS22475	COG2132	Multicopper oxidase
DIU31_RS22495	COG2217	Heavy metal translocating P-type atpase
DIU31_RS22520	COG0745	RESPONSE REGULATOR receiver
DIU31_RS22530	COG0671	phosphoesterase, PA-phosphatase related
DIU31_RS22545	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DIU31_RS22570	COG2217	Heavy metal translocating P-type atpase
DIU31_RS22690	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DIU31_RS22745	COG1629	transport
DIU31_RS22745	COG4206	TonB-dependent receptor
DIU31_RS22780	COG2972	Histidine kinase
DIU31_RS22785	COG3279	Response regulator of the LytR AlgR family
DIU31_RS22790	COG3279	Response regulator of the LytR AlgR family
DIU31_RS22995	COG0582	viral genome integration into host DNA
DIU31_RS23025	COG2310	stress, protein
DIU31_RS23045	COG2310	stress, protein
DIU31_RS23055	COG3853	Toxic anion resistance protein (TelA)
DIU31_RS23070	COG0450	alkyl hydroperoxide reductase
DIU31_RS23075	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DIU31_RS23080	COG2814	Major facilitator Superfamily
DIU31_RS23095	COG1309	transcriptional regulator
DIU31_RS23105	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DIU31_RS23110	COG0436	Aminotransferase
DIU31_RS23120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DIU31_RS23130	COG1809	phosphosulfolactate synthase activity
DIU31_RS23140	COG1012	belongs to the aldehyde dehydrogenase family
DIU31_RS23155	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DIU31_RS23160	COG0416	fatty acid biosynthetic process
DIU31_RS23165	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DIU31_RS23170	COG0511	ligase activity, forming carbon-carbon bonds
DIU31_RS23175	COG0439	Biotin carboxylase
DIU31_RS23180	COG0805	protein transport
DIU31_RS23185	COG0698	ribose 5-phosphate isomerase
DIU31_RS23190	COG2234	aminopeptidase activity
DIU31_RS23195	COG1139	Iron-sulfur cluster binding protein
DIU31_RS23200	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DIU31_RS23220	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DIU31_RS23225	COG2205	protein histidine kinase activity
DIU31_RS23225	COG3292	Two component regulator propeller
DIU31_RS23225	COG0745	RESPONSE REGULATOR receiver
DIU31_RS23240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DIU31_RS23245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DIU31_RS23250	COG0571	ribonuclease III activity
DIU31_RS23260	COG1561	YicC-like family, N-terminal region
DIU31_RS23265	COG0194	GDP metabolic process
DIU31_RS23270	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DIU31_RS23280	COG1793	dna ligase
DIU31_RS23290	COG1619	proteins homologs of microcin C7 resistance protein MccF
DIU31_RS23295	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DIU31_RS23295	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DIU31_RS23305	COG4974	Belongs to the 'phage' integrase family
DIU31_RS23355	COG1484	DNA-dependent DNA replication
DIU31_RS23360	COG4584	PFAM Integrase catalytic
DIU31_RS23440	COG0488	(ABC) transporter
DIU31_RS23450	COG2345	Transcriptional regulator
DIU31_RS23455	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS23470	COG0488	(ABC) transporter
DIU31_RS23495	COG0612	Peptidase, M16
DIU31_RS23510	COG0363	glucosamine-6-phosphate deaminase activity
DIU31_RS23515	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DIU31_RS23525	COG2885	chlorophyll binding
DIU31_RS23550	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DIU31_RS23560	COG1629	transport
DIU31_RS23570	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DIU31_RS23590	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS23595	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS23600	COG4977	sequence-specific DNA binding
DIU31_RS23615	COG1595	DNA-templated transcription, initiation
DIU31_RS23635	COG2361	Protein of unknown function DUF86
DIU31_RS23650	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DIU31_RS23700	COG1530	ribonuclease E activity
DIU31_RS23710	COG0776	regulation of translation
DIU31_RS23715	COG1194	a g-specific adenine glycosylase
DIU31_RS23745	COG3386	PFAM SMP-30 Gluconolaconase
DIU31_RS23760	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DIU31_RS23770	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DIU31_RS23775	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DIU31_RS23780	COG0297	glycogen (starch) synthase activity
DIU31_RS23790	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DIU31_RS23795	COG0861	Integral membrane protein TerC family
DIU31_RS23800	COG1501	Belongs to the glycosyl hydrolase 31 family
DIU31_RS23830	COG0129	dihydroxy-acid dehydratase activity
DIU31_RS23835	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS23840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DIU31_RS23850	COG0366	Alpha amylase catalytic
DIU31_RS23890	COG0529	Catalyzes the synthesis of activated sulfate
DIU31_RS23895	COG2226	methyltransferase
DIU31_RS23910	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DIU31_RS23920	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DIU31_RS23920	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DIU31_RS23965	COG1484	DNA-dependent DNA replication
DIU31_RS23970	COG4584	PFAM Integrase catalytic
DIU31_RS24075	COG0004	ammonium transporteR
DIU31_RS24080	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DIU31_RS24090	COG5002	protein histidine kinase activity
DIU31_RS24115	COG1629	transport
DIU31_RS24115	COG4206	TonB-dependent receptor
DIU31_RS24130	COG5001	Diguanylate cyclase
DIU31_RS24135	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DIU31_RS24250	COG3279	Response regulator of the LytR AlgR family
DIU31_RS24295	COG0778	Nitroreductase
DIU31_RS24310	COG0702	epimerase
DIU31_RS24315	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
DIU31_RS24325	COG3258	Cytochrome c
DIU31_RS24355	COG0583	DNA-binding transcription factor activity
DIU31_RS24365	COG3275	phosphorelay sensor kinase activity
DIU31_RS24370	COG3279	Response regulator of the LytR AlgR family
DIU31_RS24465	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DIU31_RS24470	COG0745	RESPONSE REGULATOR receiver
DIU31_RS24470	COG2205	protein histidine kinase activity
DIU31_RS24470	COG3292	Two component regulator propeller
DIU31_RS24500	COG5000	phosphorelay sensor kinase activity
DIU31_RS24505	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DIU31_RS24510	COG0302	gtp cyclohydrolase
DIU31_RS24525	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
DIU31_RS24530	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DIU31_RS24545	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DIU31_RS24550	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DIU31_RS24560	COG1472	Belongs to the glycosyl hydrolase 3 family
DIU31_RS24565	COG1515	deoxyribonuclease V activity
DIU31_RS24580	COG1381	Involved in DNA repair and RecF pathway recombination
DIU31_RS24610	COG0363	glucosamine-6-phosphate deaminase activity
DIU31_RS24615	COG0673	inositol 2-dehydrogenase activity
DIU31_RS24630	COG0037	tRNA processing
DIU31_RS24650	COG0583	DNA-binding transcription factor activity
DIU31_RS24705	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DIU31_RS24720	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DIU31_RS24725	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DIU31_RS24730	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DIU31_RS24740	COG0714	Associated with various cellular activities
DIU31_RS24785	COG0438	transferase activity, transferring glycosyl groups
DIU31_RS24785	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DIU31_RS24795	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DIU31_RS24800	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS24820	COG0366	Alpha amylase catalytic
DIU31_RS24860	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DIU31_RS24860	COG2755	lipolytic protein G-D-S-L family
DIU31_RS24985	COG0542	response to heat
DIU31_RS25000	COG0628	permease
DIU31_RS25025	COG0148	phosphopyruvate hydratase activity
DIU31_RS25030	COG0038	chloride channel
DIU31_RS25040	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DIU31_RS25050	COG0671	phosphoesterase, PA-phosphatase related
DIU31_RS25065	COG0671	phosphoesterase, PA-phosphatase related
DIU31_RS25105	COG5002	protein histidine kinase activity
DIU31_RS25110	COG0745	RESPONSE REGULATOR receiver
DIU31_RS25120	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DIU31_RS25125	COG1160	GTP binding
DIU31_RS25135	COG0492	ferredoxin-NADP+ reductase activity
DIU31_RS25145	COG3409	Peptidoglycan-binding domain 1 protein
DIU31_RS25145	COG0793	Belongs to the peptidase S41A family
DIU31_RS25150	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DIU31_RS25160	COG0670	Belongs to the BI1 family
DIU31_RS25170	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DIU31_RS25200	COG3851	Histidine kinase
DIU31_RS25220	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
DIU31_RS25225	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DIU31_RS25230	COG1174	glycine betaine transport
DIU31_RS25235	COG0517	IMP dehydrogenase activity
DIU31_RS25235	COG1125	glycine betaine transport
DIU31_RS25295	COG3547	Transposase (IS116 IS110 IS902 family)
DIU31_RS25340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DIU31_RS25375	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DIU31_RS25405	COG0656	L-ascorbic acid biosynthetic process
DIU31_RS25410	COG0667	Aldo Keto reductase
DIU31_RS25420	COG0667	Aldo Keto reductase
DIU31_RS25425	COG0716	FMN binding
DIU31_RS25440	COG4804	nuclease activity
DIU31_RS25495	COG2267	carboxylic ester hydrolase activity
DIU31_RS25505	COG0024	Methionine aminopeptidase
DIU31_RS25515	COG2207	Transcriptional regulator
DIU31_RS25515	COG1917	Cupin 2, conserved barrel domain protein
DIU31_RS25520	COG0577	efflux transmembrane transporter activity
DIU31_RS25525	COG3279	Response regulator of the LytR AlgR family
DIU31_RS25530	COG2972	Histidine kinase
DIU31_RS25570	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DIU31_RS25575	COG4206	TonB-dependent receptor
DIU31_RS25575	COG1629	transport
DIU31_RS25595	COG0346	lactoylglutathione lyase activity
DIU31_RS25615	COG1942	4-Oxalocrotonate Tautomerase
DIU31_RS25620	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS25630	COG2070	2-Nitropropane dioxygenase
DIU31_RS25640	COG0589	response to stress
DIU31_RS25640	COG0475	glutathione-regulated potassium exporter activity
DIU31_RS25650	COG0736	holo-[acyl-carrier-protein] synthase activity
DIU31_RS25665	COG0204	Acyl-transferase
DIU31_RS25685	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS25695	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DIU31_RS25700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DIU31_RS25725	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DIU31_RS25740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DIU31_RS25745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DIU31_RS25755	COG0726	polysaccharide deacetylase
DIU31_RS25770	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DIU31_RS25795	COG1694	Mazg nucleotide pyrophosphohydrolase
DIU31_RS25815	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DIU31_RS25820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DIU31_RS25870	COG1051	belongs to the nudix hydrolase family
DIU31_RS25875	COG0604	alcohol dehydrogenase
DIU31_RS25875	COG3321	synthase
DIU31_RS25880	COG2321	neutral zinc metallopeptidase
DIU31_RS25890	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DIU31_RS25895	COG3685	Protein conserved in bacteria
DIU31_RS25915	COG3023	N-Acetylmuramoyl-L-alanine amidase
DIU31_RS25935	COG4115	mRNA cleavage
DIU31_RS25960	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DIU31_RS25980	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS25985	COG1309	transcriptional regulator
DIU31_RS25990	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DIU31_RS25995	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DIU31_RS26000	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DIU31_RS26005	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DIU31_RS26025	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DIU31_RS26045	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DIU31_RS26050	COG0612	Peptidase, M16
DIU31_RS26055	COG0242	peptide deformylase activity
DIU31_RS26070	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DIU31_RS26075	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
DIU31_RS26085	COG1595	DNA-templated transcription, initiation
DIU31_RS26100	COG1490	D-aminoacyl-tRNA deacylase activity
DIU31_RS26105	COG0626	cystathionine gamma-synthase activity
DIU31_RS26115	COG1162	GTPase activity
DIU31_RS26120	COG0460	homoserine dehydrogenase
DIU31_RS26120	COG0527	aspartate kinase activity
DIU31_RS26125	COG0083	homoserine kinase activity
DIU31_RS26130	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DIU31_RS26155	COG1045	serine acetyltransferase
DIU31_RS26180	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DIU31_RS26185	COG2172	sigma factor antagonist activity
DIU31_RS26220	COG0726	polysaccharide deacetylase
DIU31_RS26255	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
DIU31_RS26270	COG0640	Transcriptional regulator
DIU31_RS26290	COG3275	phosphorelay sensor kinase activity
DIU31_RS26340	COG0745	RESPONSE REGULATOR receiver
DIU31_RS26345	COG1609	Transcriptional regulator
DIU31_RS26365	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DIU31_RS26375	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DIU31_RS26380	COG0489	protein tyrosine kinase activity
DIU31_RS26385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DIU31_RS26415	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DIU31_RS26420	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DIU31_RS26425	COG1741	Belongs to the pirin family
DIU31_RS26435	COG0488	(ABC) transporter
DIU31_RS26445	COG0445	tRNA wobble uridine modification
DIU31_RS26455	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DIU31_RS26470	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DIU31_RS26475	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DIU31_RS26480	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DIU31_RS26515	COG1774	PSP1 C-terminal conserved region
DIU31_RS26520	COG0470	DNA polymerase III
DIU31_RS26525	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DIU31_RS26540	COG0791	NLP P60 protein
DIU31_RS26540	COG1388	LysM domain
DIU31_RS26570	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DIU31_RS26590	COG2204	response regulator
DIU31_RS26625	COG0606	chelatase, subunit chli
DIU31_RS26675	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DIU31_RS26680	COG1131	(ABC) transporter
DIU31_RS26685	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DIU31_RS26690	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DIU31_RS26690	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DIU31_RS26695	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DIU31_RS26700	COG1078	dGTPase activity
DIU31_RS26710	COG0708	Exodeoxyribonuclease III
DIU31_RS26735	COG0802	atpase or kinase
DIU31_RS26740	COG0686	Belongs to the AlaDH PNT family
DIU31_RS26750	COG1295	ribonuclease BN
DIU31_RS26755	COG0124	histidyl-tRNA synthetase
DIU31_RS26780	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DIU31_RS26800	COG0724	RNA recognition motif
DIU31_RS26805	COG0784	Response regulator, receiver
DIU31_RS26805	COG2205	protein histidine kinase activity
DIU31_RS26820	COG1215	transferase activity, transferring glycosyl groups
DIU31_RS26825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DIU31_RS26835	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DIU31_RS26845	COG1305	Transglutaminase-like
DIU31_RS26855	COG2308	Evidence 4 Homologs of previously reported genes of
DIU31_RS26900	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DIU31_RS26905	COG1574	metal-dependent hydrolase with the TIM-barrel fold
DIU31_RS26910	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DIU31_RS26930	COG0215	cysteine-tRNA ligase activity
DIU31_RS26945	COG0714	Associated with various cellular activities
DIU31_RS26950	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DIU31_RS26960	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DIU31_RS26970	COG2706	6-phosphogluconolactonase activity
DIU31_RS26975	COG1187	pseudouridine synthase activity
DIU31_RS26985	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DIU31_RS26990	COG2161	toxin-antitoxin pair type II binding
DIU31_RS26995	COG4115	mRNA cleavage
DIU31_RS27010	COG2353	YceI-like domain
DIU31_RS27015	COG3424	synthase
DIU31_RS27030	COG5002	protein histidine kinase activity
DIU31_RS27040	COG0306	phosphate transporter
DIU31_RS27080	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DIU31_RS27085	COG0195	Participates in both transcription termination and antitermination
DIU31_RS27090	COG0779	Required for maturation of 30S ribosomal subunits
DIU31_RS27110	COG0823	Involved in the tonB-independent uptake of proteins
DIU31_RS27110	COG4946	Tricorn protease homolog
DIU31_RS27110	COG1506	peptidase
DIU31_RS27135	COG2195	Cleaves the N-terminal amino acid of tripeptides
DIU31_RS27165	COG4948	Mandelate Racemase Muconate Lactonizing
DIU31_RS27170	COG3237	CsbD-like
DIU31_RS27185	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DIU31_RS27195	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DIU31_RS27200	COG2814	Major facilitator Superfamily
DIU31_RS27210	COG0640	Transcriptional regulator
DIU31_RS27225	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DIU31_RS27235	COG0798	PFAM Bile acid sodium symporter
DIU31_RS27265	COG0640	Transcriptional regulator
DIU31_RS27285	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DIU31_RS27330	COG2217	Heavy metal translocating P-type atpase
DIU31_RS27335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DIU31_RS27345	COG2132	Multicopper oxidase
DIU31_RS27375	COG4106	trans-aconitate 2-methyltransferase activity
DIU31_RS27380	COG4771	TonB-dependent receptor
DIU31_RS27400	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DIU31_RS27420	COG2132	Multicopper oxidase
DIU31_RS27435	COG2217	Heavy metal translocating P-type atpase
DIU31_RS27490	COG0750	zinc metalloprotease
DIU31_RS27495	COG0750	zinc metalloprotease
DIU31_RS27500	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DIU31_RS27530	COG1914	H( )-stimulated, divalent metal cation uptake system
DIU31_RS27535	COG2217	Heavy metal translocating P-type atpase
DIU31_RS27555	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DIU31_RS27555	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DIU31_RS27695	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
DIU31_RS27700	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DIU31_RS27775	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
DIU31_RS27780	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
DIU31_RS27790	COG1269	ATP hydrolysis coupled proton transport
DIU31_RS27800	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DIU31_RS27805	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DIU31_RS27830	COG2217	Heavy metal translocating P-type atpase
DIU31_RS27875	COG2132	Multicopper oxidase
DIU31_RS27900	COG1484	DNA-dependent DNA replication
DIU31_RS27905	COG4584	PFAM Integrase catalytic
DIU31_RS27930	COG4974	Belongs to the 'phage' integrase family
DIU31_RS27950	COG1733	regulation of RNA biosynthetic process
DIU31_RS27955	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS27960	COG4232	protein-disulfide reductase activity
DIU31_RS27965	COG0612	Peptidase, M16
DIU31_RS27980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DIU31_RS27990	COG1629	transport
DIU31_RS27990	COG4206	TonB-dependent receptor
DIU31_RS28000	COG1595	DNA-templated transcription, initiation
DIU31_RS28005	COG1408	metallophosphoesterase
DIU31_RS28010	COG0025	NhaP-type Na H and K H
DIU31_RS28015	COG0778	Nitroreductase
DIU31_RS28025	COG1064	alcohol dehydrogenase
DIU31_RS28040	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
DIU31_RS28045	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS28050	COG1309	transcriptional regulator
DIU31_RS28080	COG2267	carboxylic ester hydrolase activity
DIU31_RS28095	COG1082	Xylose isomerase domain protein TIM barrel
DIU31_RS28100	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DIU31_RS28115	COG0561	phosphatase activity
DIU31_RS28120	COG1629	transport
DIU31_RS28135	COG2207	Transcriptional regulator
DIU31_RS28135	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DIU31_RS28140	COG1012	belongs to the aldehyde dehydrogenase family
DIU31_RS28145	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS28150	COG1024	Enoyl-CoA hydratase
DIU31_RS28160	COG1309	transcriptional regulator
DIU31_RS28270	COG1396	sequence-specific DNA binding
DIU31_RS28280	COG1629	transport
DIU31_RS28280	COG4206	TonB-dependent receptor
DIU31_RS28505	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DIU31_RS28515	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DIU31_RS28550	COG0745	RESPONSE REGULATOR receiver
DIU31_RS28550	COG2205	protein histidine kinase activity
DIU31_RS28550	COG3292	Two component regulator propeller
DIU31_RS28555	COG1629	transport
DIU31_RS28575	COG3507	Belongs to the glycosyl hydrolase 43 family
DIU31_RS28585	COG3507	Belongs to the glycosyl hydrolase 43 family
DIU31_RS28600	COG1690	Belongs to the RtcB family
DIU31_RS28605	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DIU31_RS28635	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DIU31_RS28650	COG2272	Belongs to the type-B carboxylesterase lipase family
DIU31_RS28670	COG0531	amino acid
DIU31_RS28675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DIU31_RS28680	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DIU31_RS28685	COG1024	Enoyl-CoA hydratase
DIU31_RS28690	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DIU31_RS28690	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DIU31_RS28720	COG1090	epimerase
DIU31_RS28725	COG2130	NADP-dependent
DIU31_RS28735	COG0583	DNA-binding transcription factor activity
DIU31_RS28755	COG0509	glycine decarboxylation via glycine cleavage system
DIU31_RS28765	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DIU31_RS28770	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DIU31_RS28775	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DIU31_RS28785	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DIU31_RS28790	COG0297	glycogen (starch) synthase activity
DIU31_RS28805	COG0519	Catalyzes the synthesis of GMP from XMP
DIU31_RS28835	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DIU31_RS28860	COG0628	permease
DIU31_RS28880	COG0363	glucosamine-6-phosphate deaminase activity
DIU31_RS28885	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DIU31_RS28890	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DIU31_RS28900	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DIU31_RS28905	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DIU31_RS28910	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DIU31_RS28940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DIU31_RS28955	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DIU31_RS28965	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
DIU31_RS28970	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DIU31_RS28975	COG0552	protein localization to endoplasmic reticulum
DIU31_RS28985	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DIU31_RS28990	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DIU31_RS28995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DIU31_RS29005	COG2967	ApaG domain
DIU31_RS29010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DIU31_RS29025	COG4589	Belongs to the CDS family
DIU31_RS29035	COG0335	large ribosomal subunit rRNA binding
DIU31_RS29060	COG0336	Belongs to the RNA methyltransferase TrmD family
DIU31_RS29090	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DIU31_RS29095	COG0228	four-way junction DNA binding
DIU31_RS29100	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
DIU31_RS29110	COG0205	6-phosphofructokinase activity
DIU31_RS29115	COG4232	protein-disulfide reductase activity
DIU31_RS29135	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DIU31_RS29140	COG1556	Lactate utilization protein
DIU31_RS29160	COG2197	response regulator
DIU31_RS29170	COG2205	protein histidine kinase activity
DIU31_RS29180	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DIU31_RS29195	COG4221	oxidoreductase activity
DIU31_RS29205	COG0577	efflux transmembrane transporter activity
DIU31_RS29205	COG1136	(ABC) transporter
DIU31_RS29220	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DIU31_RS29225	COG0514	ATP-dependent DNA helicase (RecQ)
DIU31_RS29240	COG1983	PspC domain protein
DIU31_RS29245	COG1695	Transcriptional regulator
DIU31_RS29265	COG2259	Doxx family
DIU31_RS29285	COG1649	PFAM Uncharacterised BCR, COG1649
DIU31_RS29315	COG2885	chlorophyll binding
DIU31_RS29320	COG5002	protein histidine kinase activity
DIU31_RS29325	COG0745	RESPONSE REGULATOR receiver
DIU31_RS29350	COG1522	sequence-specific DNA binding
DIU31_RS29380	COG0793	Belongs to the peptidase S41A family
DIU31_RS29390	COG1360	Flagellar Motor Protein
DIU31_RS29420	COG0508	dehydrogenase complex catalyzes the overall conversion of
DIU31_RS29420	COG0022	dehydrogenase e1 component
DIU31_RS29435	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DIU31_RS29440	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DIU31_RS29450	COG0022	dehydrogenase e1 component
DIU31_RS29470	COG1082	Xylose isomerase domain protein TIM barrel
DIU31_RS29480	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DIU31_RS29500	COG3279	Response regulator of the LytR AlgR family
DIU31_RS29510	COG0545	Peptidyl-prolyl cis-trans isomerase
DIU31_RS29520	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DIU31_RS29595	COG0791	NLP P60 protein
DIU31_RS29600	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DIU31_RS29605	COG0508	dehydrogenase complex catalyzes the overall conversion of
DIU31_RS29625	COG0134	indole-3-glycerol-phosphate synthase activity
DIU31_RS29645	COG1505	serine-type exopeptidase activity
DIU31_RS29670	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DIU31_RS29675	COG2183	response to ionizing radiation
DIU31_RS29680	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
DIU31_RS29685	COG0714	Associated with various cellular activities
DIU31_RS29725	COG1760	l-serine dehydratase
DIU31_RS29745	COG0321	lipoyl(octanoyl) transferase activity
DIU31_RS29760	COG1629	transport
DIU31_RS29765	COG1629	transport
DIU31_RS29775	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DIU31_RS29785	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DIU31_RS29790	COG3483	tryptophan 2,3-dioxygenase activity
DIU31_RS29805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DIU31_RS29810	COG0010	Belongs to the arginase family
DIU31_RS29815	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DIU31_RS29820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DIU31_RS29845	COG0196	riboflavin kinase activity
DIU31_RS29850	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DIU31_RS29855	COG1968	undecaprenyl-diphosphatase activity
DIU31_RS29865	COG2177	Part of the ABC transporter FtsEX involved in
DIU31_RS29875	COG1132	(ABC) transporter
DIU31_RS29880	COG0101	tRNA pseudouridine synthase activity
DIU31_RS29910	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DIU31_RS29950	COG0438	transferase activity, transferring glycosyl groups
DIU31_RS29960	COG0038	chloride channel
DIU31_RS29990	COG0726	polysaccharide deacetylase
DIU31_RS30015	COG1629	transport
DIU31_RS30015	COG4206	TonB-dependent receptor
DIU31_RS30020	COG0702	epimerase
DIU31_RS30030	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DIU31_RS30035	COG0006	proline dipeptidase activity
DIU31_RS30050	COG0513	Belongs to the DEAD box helicase family
DIU31_RS30055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DIU31_RS30060	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DIU31_RS30100	COG0673	inositol 2-dehydrogenase activity
DIU31_RS30110	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DIU31_RS30115	COG2045	Belongs to the ComB family
DIU31_RS30120	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DIU31_RS30125	COG3852	Histidine kinase
DIU31_RS30150	COG1053	succinate dehydrogenase
DIU31_RS30165	COG0492	ferredoxin-NADP+ reductase activity
DIU31_RS30170	COG0583	DNA-binding transcription factor activity
DIU31_RS30180	COG2197	response regulator
DIU31_RS30230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DIU31_RS30245	COG1595	DNA-templated transcription, initiation
DIU31_RS30255	COG0861	Integral membrane protein TerC family
DIU31_RS30260	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DIU31_RS30280	COG0116	Belongs to the methyltransferase superfamily
DIU31_RS30280	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DIU31_RS30295	COG1418	mRNA catabolic process
DIU31_RS30305	COG0537	adenosine 5'-monophosphoramidase activity
DIU31_RS30310	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DIU31_RS30335	COG0352	thiamine-phosphate diphosphorylase activity
DIU31_RS30360	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DIU31_RS30370	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DIU31_RS30380	COG1960	acyl-CoA dehydrogenase activity
DIU31_RS30390	COG3590	peptidase
DIU31_RS30395	COG1012	belongs to the aldehyde dehydrogenase family
DIU31_RS30400	COG0668	transmembrane transport
DIU31_RS30405	COG0459	protein refolding
DIU31_RS30410	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DIU31_RS30490	COG0745	RESPONSE REGULATOR receiver
DIU31_RS30505	COG1408	metallophosphoesterase
DIU31_RS30520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DIU31_RS30555	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
DIU31_RS30560	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DIU31_RS30565	COG4974	Belongs to the 'phage' integrase family
DIU31_RS30600	COG3547	Transposase (IS116 IS110 IS902 family)
DIU31_RS30630	COG0443	Heat shock 70 kDa protein
DIU31_RS30660	COG0589	response to stress
DIU31_RS30670	COG3383	formate dehydrogenase (NAD+) activity
DIU31_RS30680	COG0778	Nitroreductase
DIU31_RS30700	COG4589	Belongs to the CDS family
DIU31_RS30730	COG0071	Belongs to the small heat shock protein (HSP20) family
DIU31_RS30755	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DIU31_RS30780	COG0322	excinuclease ABC activity
DIU31_RS30785	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DIU31_RS30805	COG0356	it plays a direct role in the translocation of protons across the membrane
DIU31_RS30810	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DIU31_RS30815	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DIU31_RS30820	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DIU31_RS30825	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DIU31_RS30830	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DIU31_RS30850	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DIU31_RS30850	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DIU31_RS30865	COG0405	Gamma-glutamyltransferase
DIU31_RS30885	COG0415	Belongs to the DNA photolyase family
DIU31_RS30890	COG1090	epimerase
DIU31_RS30895	COG0702	epimerase
DIU31_RS30905	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DIU31_RS30915	COG3118	belongs to the thioredoxin family
DIU31_RS30995	COG1595	DNA-templated transcription, initiation
DIU31_RS31015	COG0051	transcription antitermination factor activity, RNA binding
DIU31_RS31020	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DIU31_RS31025	COG0049	tRNA binding
DIU31_RS31030	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DIU31_RS31055	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DIU31_RS31055	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DIU31_RS31085	COG0017	Asparaginyl-tRNA synthetase
DIU31_RS31105	COG0358	DNA primase activity
DIU31_RS31110	COG0792	nuclease activity
DIU31_RS31140	COG0657	acetylesterase activity
DIU31_RS31140	COG2755	lipolytic protein G-D-S-L family
DIU31_RS31155	COG3279	Response regulator of the LytR AlgR family
DIU31_RS31160	COG3275	phosphorelay sensor kinase activity
DIU31_RS31190	COG0437	4 iron, 4 sulfur cluster binding
DIU31_RS31220	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DIU31_RS31230	COG0109	protoheme IX farnesyltransferase activity
DIU31_RS31235	COG1845	cytochrome c oxidase, subunit III
DIU31_RS31240	COG1845	cytochrome c oxidase, subunit III
DIU31_RS31250	COG1999	signal sequence binding
DIU31_RS31255	COG2322	membrane
DIU31_RS31285	COG2986	histidine ammonia-lyase
DIU31_RS31290	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DIU31_RS31295	COG1228	amidohydrolase
DIU31_RS31360	COG4771	TonB-dependent receptor
DIU31_RS31375	COG2201	protein-glutamate methylesterase activity
DIU31_RS31385	COG1621	beta-fructofuranosidase activity
DIU31_RS31390	COG0702	epimerase
DIU31_RS31395	COG1629	transport
DIU31_RS31405	COG2814	Major facilitator Superfamily
DIU31_RS31405	COG0477	Major facilitator Superfamily
DIU31_RS31410	COG2205	protein histidine kinase activity
DIU31_RS31410	COG0745	RESPONSE REGULATOR receiver
DIU31_RS31410	COG3292	Two component regulator propeller
DIU31_RS31445	COG1742	UPF0060 membrane protein
DIU31_RS31455	COG2197	response regulator
DIU31_RS31465	COG0156	8-amino-7-oxononanoate synthase activity
DIU31_RS31490	COG4206	TonB-dependent receptor
DIU31_RS31490	COG1629	transport
DIU31_RS31520	COG5002	protein histidine kinase activity
DIU31_RS31610	COG1914	H( )-stimulated, divalent metal cation uptake system
DIU31_RS31615	COG2217	Heavy metal translocating P-type atpase
DIU31_RS31985	COG3279	Response regulator of the LytR AlgR family
DIU31_RS31990	COG2972	Histidine kinase
DIU31_RS32025	COG2181	nitrate reductase activity
DIU31_RS32025	COG0247	lactate metabolic process
DIU31_RS32030	COG2181	nitrate reductase activity
DIU31_RS32030	COG0247	lactate metabolic process
DIU31_RS32065	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DIU31_RS32070	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DIU31_RS32075	COG0052	Belongs to the universal ribosomal protein uS2 family
DIU31_RS32080	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DIU31_RS32085	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DIU31_RS32090	COG0528	UMP kinase activity
DIU31_RS32100	COG0577	efflux transmembrane transporter activity
DIU31_RS32105	COG0577	efflux transmembrane transporter activity
DIU31_RS32105	COG1136	(ABC) transporter
DIU31_RS32110	COG0577	efflux transmembrane transporter activity
DIU31_RS32115	COG0577	efflux transmembrane transporter activity
DIU31_RS32120	COG0653	protein targeting
DIU31_RS32155	COG1192	Involved in chromosome partitioning
DIU31_RS32160	COG1475	DNA binding
DIU31_RS32170	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DIU31_RS32175	COG0681	Belongs to the peptidase S26 family
DIU31_RS32180	COG0681	Belongs to the peptidase S26 family
DIU31_RS32185	COG0681	Belongs to the peptidase S26 family
DIU31_RS32195	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DIU31_RS32210	COG1595	DNA-templated transcription, initiation
DIU31_RS32215	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DIU31_RS32255	COG0667	Aldo Keto reductase
DIU31_RS32275	COG4771	TonB-dependent receptor
DIU31_RS32315	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DIU31_RS32315	COG0116	Belongs to the methyltransferase superfamily
DIU31_RS32320	COG1127	ABC transporter
DIU31_RS32325	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DIU31_RS32330	COG1028	Short-chain dehydrogenase reductase Sdr
DIU31_RS32350	COG1051	belongs to the nudix hydrolase family
DIU31_RS32380	COG1764	response to oxidative stress
DIU31_RS32400	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DIU31_RS32405	COG0088	Forms part of the polypeptide exit tunnel
DIU31_RS32410	COG0089	rRNA binding
DIU31_RS32415	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DIU31_RS32420	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DIU31_RS32425	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DIU31_RS32430	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DIU31_RS32435	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DIU31_RS32440	COG0255	Belongs to the universal ribosomal protein uL29 family
DIU31_RS32445	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DIU31_RS32450	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DIU31_RS32455	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DIU31_RS32460	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DIU31_RS32465	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DIU31_RS32470	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DIU31_RS32475	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DIU31_RS32485	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DIU31_RS32490	COG1841	ribosomal large subunit assembly
DIU31_RS32495	COG0200	Binds to the 23S rRNA
DIU31_RS32510	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DIU31_RS32515	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DIU31_RS32520	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DIU31_RS32525	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DIU31_RS32530	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DIU31_RS32535	COG0202	RNA polymerase activity
DIU31_RS32540	COG0203	ribosomal protein L17
DIU31_RS32555	COG0443	Heat shock 70 kDa protein
DIU31_RS32560	COG0495	leucyl-tRNA aminoacylation
DIU31_RS32570	COG3781	membrane
DIU31_RS32585	COG0825	malonyl-CoA metabolic process
DIU31_RS32605	COG1874	Beta-galactosidase
DIU31_RS32615	COG2205	protein histidine kinase activity
DIU31_RS32620	COG0745	RESPONSE REGULATOR receiver
DIU31_RS32640	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DIU31_RS32645	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DIU31_RS32650	COG0193	aminoacyl-tRNA hydrolase activity
DIU31_RS32665	COG1393	Belongs to the ArsC family
DIU31_RS32680	COG4221	oxidoreductase activity
DIU31_RS32700	COG0745	RESPONSE REGULATOR receiver
DIU31_RS32700	COG2972	Histidine kinase
DIU31_RS32710	COG3842	ATPase activity
DIU31_RS32740	COG1981	membrane
DIU31_RS32745	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DIU31_RS32760	COG5002	protein histidine kinase activity
DIU31_RS32770	COG0113	porphobilinogen synthase activity
DIU31_RS32775	COG0181	hydroxymethylbilane synthase activity
DIU31_RS32790	COG0577	efflux transmembrane transporter activity
DIU31_RS32800	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DIU31_RS32810	COG3153	acetyltransferase
DIU31_RS32810	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DIU31_RS32840	COG1714	RDD family
DIU31_RS32850	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DIU31_RS32855	COG0151	Belongs to the GarS family
DIU31_RS32870	COG1196	nuclear chromosome segregation
DIU31_RS32870	COG0741	lytic transglycosylase activity
DIU31_RS32870	COG0739	heme binding
DIU31_RS32880	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DIU31_RS32885	COG4771	TonB-dependent receptor
DIU31_RS32915	COG0513	Belongs to the DEAD box helicase family
DIU31_RS32920	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DIU31_RS32925	COG0148	phosphopyruvate hydratase activity
DIU31_RS32975	COG4772	TonB-dependent receptor
DIU31_RS32980	COG0745	RESPONSE REGULATOR receiver
DIU31_RS32985	COG1435	thymidine kinase activity
DIU31_RS32995	COG0772	Belongs to the SEDS family
DIU31_RS33000	COG0768	penicillin binding
DIU31_RS33015	COG1077	Cell shape determining protein MreB Mrl
DIU31_RS33020	COG0138	bifunctional purine biosynthesis protein purh
DIU31_RS33045	COG0564	pseudouridine synthase activity
DIU31_RS33050	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DIU31_RS33055	COG0505	Belongs to the CarA family
DIU31_RS33085	COG1069	ribulokinase activity
DIU31_RS33100	COG2160	L-arabinose isomerase activity
DIU31_RS33110	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DIU31_RS33125	COG3507	Belongs to the glycosyl hydrolase 43 family
DIU31_RS33130	COG3507	Belongs to the glycosyl hydrolase 43 family
DIU31_RS33135	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DIU31_RS33140	COG1278	Cold shock
DIU31_RS33145	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DIU31_RS33155	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DIU31_RS33185	COG1519	Transferase
DIU31_RS33195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DIU31_RS33220	COG1136	(ABC) transporter
DIU31_RS33220	COG0577	efflux transmembrane transporter activity
DIU31_RS33230	COG0316	Belongs to the HesB IscA family
DIU31_RS33240	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DIU31_RS33240	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly