locus-tag	class	description
A3N99_RS00010	COG0592	DNA-directed DNA polymerase activity
A3N99_RS00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
A3N99_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
A3N99_RS00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
A3N99_RS00030	COG0187	DNA topoisomerase II activity
A3N99_RS00115	COG2814	Major facilitator Superfamily
A3N99_RS00120	COG0583	DNA-binding transcription factor activity
A3N99_RS00135	COG0457	Tetratricopeptide repeat
A3N99_RS00135	COG0705	Rhomboid family
A3N99_RS00170	COG2815	serine threonine protein kinase
A3N99_RS00170	COG0515	serine threonine protein kinase
A3N99_RS00175	COG0515	serine threonine protein kinase
A3N99_RS00180	COG0768	penicillin binding
A3N99_RS00195	COG1716	ATPase activity
A3N99_RS00200	COG1716	ATPase activity
A3N99_RS00245	COG0754	glutathionylspermidine amidase activity
A3N99_RS00265	COG1309	transcriptional regulator
A3N99_RS00285	COG4842	Belongs to the WXG100 family
A3N99_RS00305	COG0590	tRNA wobble adenosine to inosine editing
A3N99_RS00315	COG0583	DNA-binding transcription factor activity
A3N99_RS00325	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS00355	COG1960	acyl-CoA dehydrogenase activity
A3N99_RS00400	COG2072	flavoprotein involved in K transport
A3N99_RS00410	COG0346	lactoylglutathione lyase activity
A3N99_RS00415	COG1414	Transcriptional regulator
A3N99_RS00435	COG1053	succinate dehydrogenase
A3N99_RS00465	COG1785	Belongs to the alkaline phosphatase family
A3N99_RS00485	COG0070	glutamate synthase
A3N99_RS00485	COG0069	glutamate synthase activity
A3N99_RS00485	COG0067	glutamate synthase
A3N99_RS00515	COG1796	DNA polymerase
A3N99_RS00515	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A3N99_RS00525	COG2072	flavoprotein involved in K transport
A3N99_RS00535	COG2124	cytochrome p450
A3N99_RS00575	COG2372	response to copper ion
A3N99_RS00625	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A3N99_RS00640	COG3447	MASE1 domain protein
A3N99_RS00640	COG5001	Diguanylate cyclase
A3N99_RS00640	COG5002	protein histidine kinase activity
A3N99_RS00650	COG1528	Iron-storage protein
A3N99_RS00655	COG1528	Iron-storage protein
A3N99_RS00660	COG1316	TRANSCRIPTIONal
A3N99_RS00690	COG0406	alpha-ribazole phosphatase activity
A3N99_RS00700	COG0028	Belongs to the TPP enzyme family
A3N99_RS00730	COG2072	flavoprotein involved in K transport
A3N99_RS00740	COG2072	flavoprotein involved in K transport
A3N99_RS00760	COG1285	pathogenesis
A3N99_RS00810	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A3N99_RS00810	COG2146	nitrite reductase [NAD(P)H] activity
A3N99_RS00820	COG4133	protoheme IX ABC transporter activity
A3N99_RS00825	COG2070	2-Nitropropane dioxygenase
A3N99_RS00830	COG1942	4-Oxalocrotonate Tautomerase
A3N99_RS00835	COG0583	DNA-binding transcription factor activity
A3N99_RS00850	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS00855	COG0204	Acyl-transferase
A3N99_RS00865	COG0561	phosphatase activity
A3N99_RS00885	COG1216	Glycosyl transferase, family 2
A3N99_RS00890	COG0671	phosphoesterase, PA-phosphatase related
A3N99_RS00895	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
A3N99_RS00900	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
A3N99_RS00920	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
A3N99_RS00925	COG0318	PFAM AMP-dependent synthetase and ligase
A3N99_RS00930	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
A3N99_RS00930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A3N99_RS00930	COG3321	synthase
A3N99_RS00935	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A3N99_RS00985	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS00990	COG0277	FAD linked oxidase domain protein
A3N99_RS01005	COG2376	Dihydroxyacetone kinase
A3N99_RS01010	COG2267	carboxylic ester hydrolase activity
A3N99_RS01015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3N99_RS01020	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A3N99_RS01035	COG0671	phosphoesterase, PA-phosphatase related
A3N99_RS01045	COG1216	Glycosyl transferase, family 2
A3N99_RS01120	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A3N99_RS01125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A3N99_RS01225	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A3N99_RS01300	COG1960	acyl-CoA dehydrogenase activity
A3N99_RS01315	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS01335	COG1174	glycine betaine transport
A3N99_RS01350	COG0287	Prephenate dehydrogenase
A3N99_RS01360	COG0590	tRNA wobble adenosine to inosine editing
A3N99_RS01385	COG0343	queuine tRNA-ribosyltransferase activity
A3N99_RS01395	COG0765	amino acid transport
A3N99_RS01400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A3N99_RS01405	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A3N99_RS01410	COG1793	dna ligase
A3N99_RS01440	COG2271	Major facilitator Superfamily
A3N99_RS01445	COG0604	alcohol dehydrogenase
A3N99_RS01470	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A3N99_RS01495	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS01525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3N99_RS01550	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A3N99_RS01560	COG0148	phosphopyruvate hydratase activity
A3N99_RS01590	COG0860	N-Acetylmuramoyl-L-alanine amidase
A3N99_RS01605	COG1492	cobalamin metabolic process
A3N99_RS01630	COG1960	acyl-CoA dehydrogenase activity
A3N99_RS01645	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
A3N99_RS01675	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A3N99_RS01720	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3N99_RS01730	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A3N99_RS01760	COG2070	2-Nitropropane dioxygenase
A3N99_RS01795	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A3N99_RS01800	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A3N99_RS01805	COG2971	BadF BadG BcrA BcrD
A3N99_RS01810	COG2814	Major facilitator Superfamily
A3N99_RS01830	COG3572	ergothioneine biosynthetic process
A3N99_RS01835	COG1262	PFAM Formylglycine-generating sulfatase enzyme
A3N99_RS01840	COG0121	glutamine amidotransferase
A3N99_RS01845	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
A3N99_RS01850	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A3N99_RS01880	COG2030	dehydratase
A3N99_RS01885	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS01890	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A3N99_RS01900	COG1695	Transcriptional regulator
A3N99_RS01910	COG0569	domain protein
A3N99_RS01910	COG0475	glutathione-regulated potassium exporter activity
A3N99_RS01930	COG0714	Associated with various cellular activities
A3N99_RS01970	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A3N99_RS01975	COG1074	ATP-dependent DNA helicase activity
A3N99_RS01980	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
A3N99_RS01990	COG2755	lipolytic protein G-D-S-L family
A3N99_RS02090	COG4974	Belongs to the 'phage' integrase family
A3N99_RS02100	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A3N99_RS02105	COG1408	metallophosphoesterase
A3N99_RS02110	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
A3N99_RS02140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3N99_RS02180	COG2945	thiolester hydrolase activity
A3N99_RS02180	COG0596	Alpha beta hydrolase
A3N99_RS02195	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A3N99_RS02200	COG0747	negative chemotaxis
A3N99_RS02210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A3N99_RS02295	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A3N99_RS02370	COG0582	viral genome integration into host DNA
A3N99_RS02415	COG2217	Heavy metal translocating P-type atpase
A3N99_RS02425	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A3N99_RS02485	COG2132	Multicopper oxidase
A3N99_RS02520	COG0596	Alpha beta hydrolase
A3N99_RS02575	COG1695	Transcriptional regulator
A3N99_RS02580	COG0657	acetylesterase activity
A3N99_RS02585	COG1902	pentaerythritol trinitrate reductase activity
A3N99_RS02590	COG1111	helicase
A3N99_RS02590	COG1205	dead DEAH box helicase
A3N99_RS02595	COG1278	Cold shock
A3N99_RS02605	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A3N99_RS02605	COG1754	DNA topoisomerase type I activity
A3N99_RS02780	COG1802	Transcriptional regulator
A3N99_RS02780	COG4626	Terminase
A3N99_RS02950	COG4974	Belongs to the 'phage' integrase family
A3N99_RS03080	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A3N99_RS03115	COG2027	D-alanyl-D-alanine carboxypeptidase
A3N99_RS03145	COG1063	alcohol dehydrogenase
A3N99_RS03155	COG2267	carboxylic ester hydrolase activity
A3N99_RS03165	COG1309	transcriptional regulator
A3N99_RS03180	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3N99_RS03225	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
A3N99_RS03235	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
A3N99_RS03255	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
A3N99_RS03260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A3N99_RS03300	COG4977	sequence-specific DNA binding
A3N99_RS03305	COG1194	a g-specific adenine glycosylase
A3N99_RS03315	COG1316	TRANSCRIPTIONal
A3N99_RS03325	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
A3N99_RS03335	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A3N99_RS03355	COG1329	Transcriptional regulator
A3N99_RS03360	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
A3N99_RS03370	COG0215	cysteine-tRNA ligase activity
A3N99_RS03380	COG0584	glycerophosphoryl diester phosphodiesterase
A3N99_RS03390	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A3N99_RS03395	COG1120	ATPase activity
A3N99_RS03400	COG0803	Belongs to the bacterial solute-binding protein 9 family
A3N99_RS03410	COG1309	transcriptional regulator
A3N99_RS03415	COG1960	acyl-CoA dehydrogenase activity
A3N99_RS03425	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A3N99_RS03435	COG0346	lactoylglutathione lyase activity
A3N99_RS03475	COG1960	acyl-CoA dehydrogenase activity
A3N99_RS03480	COG1960	acyl-CoA dehydrogenase activity
A3N99_RS03485	COG1960	acyl-CoA dehydrogenase activity
A3N99_RS03490	COG0318	PFAM AMP-dependent synthetase and ligase
A3N99_RS03495	COG1960	acyl-CoA dehydrogenase activity
A3N99_RS03510	COG0183	Belongs to the thiolase family
A3N99_RS03540	COG1024	Enoyl-CoA hydratase
A3N99_RS03545	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS03550	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS03570	COG0183	Belongs to the thiolase family
A3N99_RS03580	COG1960	acyl-CoA dehydrogenase activity
A3N99_RS03585	COG1960	acyl-CoA dehydrogenase activity
A3N99_RS03590	COG2030	dehydratase
A3N99_RS03615	COG2030	dehydratase
A3N99_RS03620	COG1053	succinate dehydrogenase
A3N99_RS03630	COG3971	2-oxopent-4-enoate hydratase activity
A3N99_RS03675	COG0651	ATP synthesis coupled electron transport
A3N99_RS03685	COG2111	Na H antiporter
A3N99_RS03685	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A3N99_RS03690	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3N99_RS03710	COG0647	UMP catabolic process
A3N99_RS03745	COG4221	oxidoreductase activity
A3N99_RS03765	COG0459	protein refolding
A3N99_RS03780	COG0714	Associated with various cellular activities
A3N99_RS03830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A3N99_RS03845	COG4842	Belongs to the WXG100 family
A3N99_RS03885	COG0745	RESPONSE REGULATOR receiver
A3N99_RS03890	COG5002	protein histidine kinase activity
A3N99_RS03890	COG5000	phosphorelay sensor kinase activity
A3N99_RS03895	COG0537	adenosine 5'-monophosphoramidase activity
A3N99_RS03900	COG0697	spore germination
A3N99_RS03910	COG0596	Alpha beta hydrolase
A3N99_RS03940	COG0436	Aminotransferase
A3N99_RS03950	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A3N99_RS03970	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS03975	COG0477	Major facilitator Superfamily
A3N99_RS03980	COG0386	Belongs to the glutathione peroxidase family
A3N99_RS03990	COG3573	Dehydrogenase
A3N99_RS04000	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A3N99_RS04015	COG2837	iron assimilation
A3N99_RS04020	COG1362	aminopeptidase activity
A3N99_RS04095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A3N99_RS04105	COG0601	transmembrane transport
A3N99_RS04110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A3N99_RS04145	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
A3N99_RS04155	COG0354	folic acid binding
A3N99_RS04200	COG2897	thiosulfate sulfurtransferase activity
A3N99_RS04220	COG0745	RESPONSE REGULATOR receiver
A3N99_RS04240	COG0581	inorganic phosphate transmembrane transporter activity
A3N99_RS04245	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A3N99_RS04250	COG0604	alcohol dehydrogenase
A3N99_RS04305	COG1250	3-hydroxyacyl-CoA dehydrogenase
A3N99_RS04330	COG0697	spore germination
A3N99_RS04350	COG0442	prolyl-tRNA aminoacylation
A3N99_RS04355	COG2814	Major facilitator Superfamily
A3N99_RS04385	COG5651	PPE family
A3N99_RS04390	COG0436	Aminotransferase
A3N99_RS04410	COG0531	amino acid
A3N99_RS04415	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
A3N99_RS04420	COG1012	belongs to the aldehyde dehydrogenase family
A3N99_RS04430	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A3N99_RS04440	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A3N99_RS04445	COG1960	acyl-CoA dehydrogenase activity
A3N99_RS04450	COG1012	belongs to the aldehyde dehydrogenase family
A3N99_RS04455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A3N99_RS04470	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS04485	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS04500	COG1024	Enoyl-CoA hydratase
A3N99_RS04545	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A3N99_RS04550	COG0657	acetylesterase activity
A3N99_RS04570	COG0183	Belongs to the thiolase family
A3N99_RS04585	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A3N99_RS04605	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A3N99_RS04620	COG1061	Type III restriction enzyme res subunit
A3N99_RS04660	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A3N99_RS04680	COG1278	Cold shock
A3N99_RS04720	COG2814	Major facilitator Superfamily
A3N99_RS04795	COG1764	response to oxidative stress
A3N99_RS04800	COG1846	Transcriptional regulator
A3N99_RS04805	COG1216	Glycosyl transferase, family 2
A3N99_RS04810	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
A3N99_RS04810	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
A3N99_RS04840	COG0259	pyridoxamine-phosphate oxidase activity
A3N99_RS04850	COG0318	PFAM AMP-dependent synthetase and ligase
A3N99_RS04855	COG5651	PPE family
A3N99_RS04885	COG4977	sequence-specific DNA binding
A3N99_RS04910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3N99_RS04920	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A3N99_RS04930	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A3N99_RS04935	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS04940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3N99_RS04945	COG0545	Peptidyl-prolyl cis-trans isomerase
A3N99_RS04965	COG2072	flavoprotein involved in K transport
A3N99_RS04985	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A3N99_RS04990	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A3N99_RS05030	COG1012	belongs to the aldehyde dehydrogenase family
A3N99_RS05045	COG3022	response to hydroperoxide
A3N99_RS05055	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A3N99_RS05090	COG1309	transcriptional regulator
A3N99_RS05120	COG1393	Belongs to the ArsC family
A3N99_RS05165	COG0183	Belongs to the thiolase family
A3N99_RS05210	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A3N99_RS05250	COG0438	transferase activity, transferring glycosyl groups
A3N99_RS05255	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A3N99_RS05260	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A3N99_RS05315	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
A3N99_RS05325	COG1846	Transcriptional regulator
A3N99_RS05340	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
A3N99_RS05370	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
A3N99_RS05380	COG2326	polyphosphate kinase activity
A3N99_RS05395	COG0523	cobalamin synthesis protein
A3N99_RS05400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A3N99_RS05405	COG0235	Class ii aldolase
A3N99_RS05410	COG1396	sequence-specific DNA binding
A3N99_RS05415	COG0166	Belongs to the GPI family
A3N99_RS05460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3N99_RS05515	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A3N99_RS05545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A3N99_RS05550	COG0315	cyclic pyranopterin monophosphate synthase activity
A3N99_RS05550	COG0521	Mo-molybdopterin cofactor biosynthetic process
A3N99_RS05580	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A3N99_RS05585	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A3N99_RS05680	COG2235	arginine
A3N99_RS05695	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A3N99_RS05710	COG1252	NADH dehydrogenase
A3N99_RS05720	COG0084	hydrolase, TatD family'
A3N99_RS05725	COG3583	domain protein
A3N99_RS05740	COG2815	serine threonine protein kinase
A3N99_RS05740	COG0515	serine threonine protein kinase
A3N99_RS05760	COG0456	acetyltransferase
A3N99_RS05760	COG1846	Transcriptional regulator
A3N99_RS05770	COG0318	PFAM AMP-dependent synthetase and ligase
A3N99_RS05785	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
A3N99_RS05820	COG1309	transcriptional regulator
A3N99_RS05865	COG3956	TIGRFAM MazG family protein
A3N99_RS05880	COG2837	iron assimilation
A3N99_RS05885	COG2822	iron ion transport
A3N99_RS05920	COG0596	Alpha beta hydrolase
A3N99_RS05945	COG0318	PFAM AMP-dependent synthetase and ligase
A3N99_RS05955	COG0427	acetyl-CoA hydrolase
A3N99_RS06010	COG1846	Transcriptional regulator
A3N99_RS06025	COG1024	Enoyl-CoA hydratase
A3N99_RS06050	COG0183	Belongs to the thiolase family
A3N99_RS06055	COG2755	lipolytic protein G-D-S-L family
A3N99_RS06060	COG0657	acetylesterase activity
A3N99_RS06070	COG1714	RDD family
A3N99_RS06085	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A3N99_RS06105	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A3N99_RS06115	COG1331	Highly conserved protein containing a thioredoxin domain
A3N99_RS06120	COG3631	Ketosteroid isomerase-related protein
A3N99_RS06135	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A3N99_RS06140	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS06145	COG2124	cytochrome p450
A3N99_RS06165	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS06205	COG2272	Belongs to the type-B carboxylesterase lipase family
A3N99_RS06215	COG1174	glycine betaine transport
A3N99_RS06225	COG1174	glycine betaine transport
A3N99_RS06270	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
A3N99_RS06280	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
A3N99_RS06285	COG0726	polysaccharide deacetylase
A3N99_RS06350	COG1722	exodeoxyribonuclease VII activity
A3N99_RS06355	COG1570	exodeoxyribonuclease VII activity
A3N99_RS06365	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
A3N99_RS06380	COG1966	Carbon starvation protein
A3N99_RS06405	COG3189	MarR family transcriptional regulator
A3N99_RS06410	COG0012	GTP binding
A3N99_RS06420	COG2132	Multicopper oxidase
A3N99_RS06430	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A3N99_RS06440	COG0488	(ABC) transporter
A3N99_RS06495	COG2409	Drug exporters of the RND superfamily
A3N99_RS06530	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A3N99_RS06550	COG1716	ATPase activity
A3N99_RS06580	COG1051	belongs to the nudix hydrolase family
A3N99_RS06605	COG1217	gtp-binding protein TYPA
A3N99_RS06615	COG2015	COG2015, Alkyl sulfatase and related hydrolases
A3N99_RS06680	COG1902	pentaerythritol trinitrate reductase activity
A3N99_RS06680	COG0446	pyridine nucleotide-disulphide oxidoreductase
A3N99_RS06690	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
A3N99_RS06700	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
A3N99_RS06705	COG1012	belongs to the aldehyde dehydrogenase family
A3N99_RS06710	COG0506	proline dehydrogenase activity
A3N99_RS06715	COG0318	PFAM AMP-dependent synthetase and ligase
A3N99_RS06740	COG2207	Transcriptional regulator
A3N99_RS06755	COG1611	Belongs to the LOG family
A3N99_RS06760	COG1611	Belongs to the LOG family
A3N99_RS06765	COG0318	PFAM AMP-dependent synthetase and ligase
A3N99_RS06775	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A3N99_RS06780	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A3N99_RS06785	COG0463	Glycosyl transferase, family 2
A3N99_RS06800	COG0519	Catalyzes the synthesis of GMP from XMP
A3N99_RS06810	COG0297	glycogen (starch) synthase activity
A3N99_RS06825	COG3559	Exporter of polyketide antibiotics
A3N99_RS06830	COG1131	(ABC) transporter
A3N99_RS06835	COG1309	transcriptional regulator
A3N99_RS06845	COG1595	DNA-templated transcription, initiation
A3N99_RS06850	COG5662	AntiSigma factor
A3N99_RS06855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A3N99_RS06925	COG0598	Magnesium transport protein CorA
A3N99_RS06930	COG2095	MarC family integral membrane protein
A3N99_RS06945	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A3N99_RS06950	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A3N99_RS06970	COG3835	regulator
A3N99_RS06975	COG1073	alpha beta
A3N99_RS06980	COG0508	dehydrogenase complex catalyzes the overall conversion of
A3N99_RS06980	COG0567	Dehydrogenase, E1 component
A3N99_RS06990	COG2814	Major facilitator Superfamily
A3N99_RS07050	COG0277	FAD linked oxidase domain protein
A3N99_RS07055	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS07070	COG0668	transmembrane transport
A3N99_RS07105	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A3N99_RS07160	COG2814	Major facilitator Superfamily
A3N99_RS07190	COG0019	diaminopimelate decarboxylase activity
A3N99_RS07195	COG0460	homoserine dehydrogenase
A3N99_RS07200	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A3N99_RS07240	COG2890	protein-(glutamine-N5) methyltransferase activity
A3N99_RS07250	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A3N99_RS07260	COG0356	it plays a direct role in the translocation of protons across the membrane
A3N99_RS07265	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
A3N99_RS07290	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
A3N99_RS07350	COG0346	lactoylglutathione lyase activity
A3N99_RS07355	COG0183	Belongs to the thiolase family
A3N99_RS07360	COG2409	Drug exporters of the RND superfamily
A3N99_RS07375	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
A3N99_RS07380	COG0366	Alpha amylase catalytic
A3N99_RS07385	COG0058	SHG alpha-glucan phosphorylase activity
A3N99_RS07400	COG1335	isochorismatase
A3N99_RS07410	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A3N99_RS07425	COG3191	aminopeptidase activity
A3N99_RS07470	COG0604	alcohol dehydrogenase
A3N99_RS07490	COG0318	PFAM AMP-dependent synthetase and ligase
A3N99_RS07505	COG0419	ATPase involved in DNA repair
A3N99_RS07510	COG1024	Enoyl-CoA hydratase
A3N99_RS07520	COG0243	molybdopterin cofactor binding
A3N99_RS07535	COG2188	Transcriptional regulator
A3N99_RS07550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A3N99_RS07595	COG0596	Alpha beta hydrolase
A3N99_RS07600	COG3757	hydrolase, family 25
A3N99_RS07615	COG1051	belongs to the nudix hydrolase family
A3N99_RS07635	COG1309	transcriptional regulator
A3N99_RS07650	COG4585	Histidine kinase
A3N99_RS07655	COG2197	response regulator
A3N99_RS07665	COG2239	Acts as a magnesium transporter
A3N99_RS07675	COG0300	oxidoreductase activity
A3N99_RS07685	COG0656	L-ascorbic acid biosynthetic process
A3N99_RS07700	COG1376	ErfK ybiS ycfS ynhG family protein
A3N99_RS07715	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
A3N99_RS07720	COG0433	COG0433 Predicted ATPase
A3N99_RS07735	COG0300	oxidoreductase activity
A3N99_RS07750	COG1301	dicarboxylic acid transport
A3N99_RS07760	COG0531	amino acid
A3N99_RS07780	COG4424	Sulfotransferase
A3N99_RS07785	COG3119	arylsulfatase activity
A3N99_RS07825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3N99_RS07825	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A3N99_RS07830	COG0662	Cupin 2, conserved barrel domain protein
A3N99_RS07860	COG2902	Dehydrogenase
A3N99_RS07865	COG0824	Thioesterase
A3N99_RS07880	COG0366	Alpha amylase catalytic
A3N99_RS07915	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A3N99_RS07935	COG1309	transcriptional regulator
A3N99_RS07950	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
A3N99_RS07970	COG0740	serine-type endopeptidase activity
A3N99_RS07975	COG0740	serine-type endopeptidase activity
A3N99_RS08025	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A3N99_RS08035	COG0674	pyruvate-flavodoxin oxidoreductase activity
A3N99_RS08035	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A3N99_RS08040	COG1013	pyruvate-flavodoxin oxidoreductase activity
A3N99_RS08050	COG1388	LysM domain
A3N99_RS08080	COG0525	valine-tRNA ligase activity
A3N99_RS08085	COG0285	dihydrofolate synthase activity
A3N99_RS08100	COG1530	ribonuclease E activity
A3N99_RS08100	COG1530	ribonuclease E activity
A3N99_RS08120	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
A3N99_RS08140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A3N99_RS08145	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
A3N99_RS08150	COG0542	response to heat
A3N99_RS08160	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
A3N99_RS08170	COG0406	alpha-ribazole phosphatase activity
A3N99_RS08175	COG2755	lipolytic protein G-D-S-L family
A3N99_RS08195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A3N99_RS08230	COG2308	Evidence 4 Homologs of previously reported genes of
A3N99_RS08240	COG1305	Transglutaminase-like
A3N99_RS08270	COG3387	PFAM Glycoside hydrolase 15-related
A3N99_RS08285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A3N99_RS08320	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
A3N99_RS08325	COG4208	sulfate ABC transporter
A3N99_RS08380	COG0484	heat shock protein binding
A3N99_RS08430	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A3N99_RS08475	COG0076	glutamate decarboxylase activity
A3N99_RS08510	COG0318	PFAM AMP-dependent synthetase and ligase
A3N99_RS08560	COG0423	glycine-tRNA ligase activity
A3N99_RS08565	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A3N99_RS08570	COG2515	1-aminocyclopropane-1-carboxylate deaminase
A3N99_RS08590	COG0358	DNA primase activity
A3N99_RS09000	COG0745	RESPONSE REGULATOR receiver
A3N99_RS09005	COG5002	protein histidine kinase activity
A3N99_RS09085	COG0488	(ABC) transporter
A3N99_RS09110	COG1960	acyl-CoA dehydrogenase activity
A3N99_RS09115	COG1335	isochorismatase
A3N99_RS09125	COG0058	SHG alpha-glucan phosphorylase activity
A3N99_RS09170	COG1960	acyl-CoA dehydrogenase activity
A3N99_RS09175	COG0183	Belongs to the thiolase family
A3N99_RS09190	COG1228	amidohydrolase
A3N99_RS09220	COG0604	alcohol dehydrogenase
A3N99_RS09220	COG3321	synthase
A3N99_RS09220	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS09240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A3N99_RS09245	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A3N99_RS09270	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
A3N99_RS09340	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
A3N99_RS09345	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
A3N99_RS09405	COG0714	Associated with various cellular activities
A3N99_RS09440	COG0338	D12 class N6 adenine-specific DNA methyltransferase
A3N99_RS09450	COG0557	exoribonuclease II activity
A3N99_RS09460	COG0318	PFAM AMP-dependent synthetase and ligase
A3N99_RS09485	COG0174	glutamine synthetase
A3N99_RS09490	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
A3N99_RS09520	COG2205	protein histidine kinase activity
A3N99_RS09570	COG0174	glutamine synthetase
A3N99_RS09580	COG0477	Major facilitator Superfamily
A3N99_RS09590	COG3486	L-lysine 6-monooxygenase (NADPH) activity
A3N99_RS09615	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
A3N99_RS09620	COG0321	lipoyl(octanoyl) transferase activity
A3N99_RS09635	COG1872	DUF167
A3N99_RS09650	COG0404	The glycine cleavage system catalyzes the degradation of glycine
A3N99_RS09655	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A3N99_RS09665	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
A3N99_RS09670	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
A3N99_RS09700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A3N99_RS09745	COG2010	Cytochrome c
A3N99_RS09750	COG1845	cytochrome c oxidase, subunit III
A3N99_RS09790	COG2226	methyltransferase
A3N99_RS09815	COG0003	Pfam Anion-transporting ATPase
A3N99_RS09825	COG0204	Acyl-transferase
A3N99_RS09830	COG5650	phosphatidylinositol metabolic process
A3N99_RS09840	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
A3N99_RS09865	COG0142	geranyltranstransferase activity
A3N99_RS09905	COG0768	penicillin binding
A3N99_RS09925	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
A3N99_RS09935	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A3N99_RS09950	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A3N99_RS09975	COG0640	Transcriptional regulator
A3N99_RS10025	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A3N99_RS10035	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A3N99_RS10045	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS10075	COG2814	Major facilitator Superfamily
A3N99_RS10150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3N99_RS10155	COG2030	dehydratase
A3N99_RS10175	COG1024	Enoyl-CoA hydratase
A3N99_RS10190	COG1309	transcriptional regulator
A3N99_RS10210	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A3N99_RS10260	COG2072	flavoprotein involved in K transport
A3N99_RS10270	COG2072	flavoprotein involved in K transport
A3N99_RS10285	COG0318	PFAM AMP-dependent synthetase and ligase
A3N99_RS10290	COG1960	acyl-CoA dehydrogenase activity
A3N99_RS10310	COG1960	acyl-CoA dehydrogenase activity
A3N99_RS10355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A3N99_RS10385	COG1968	undecaprenyl-diphosphatase activity
A3N99_RS10420	COG1218	3'(2'),5'-bisphosphate nucleotidase
A3N99_RS10430	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS10455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A3N99_RS10465	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
A3N99_RS10465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A3N99_RS10480	COG2860	membrane
A3N99_RS10490	COG0646	methionine synthase
A3N99_RS10490	COG1410	methionine synthase
A3N99_RS10495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A3N99_RS10505	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
A3N99_RS10540	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A3N99_RS10545	COG1034	ATP synthesis coupled electron transport
A3N99_RS10550	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
A3N99_RS10555	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3N99_RS10595	COG1017	nitric oxide dioxygenase activity
A3N99_RS10595	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A3N99_RS10645	COG0513	Belongs to the DEAD box helicase family
A3N99_RS10685	COG0028	Belongs to the TPP enzyme family
A3N99_RS10700	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A3N99_RS10705	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A3N99_RS10710	COG4122	O-methyltransferase activity
A3N99_RS10740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A3N99_RS10745	COG4521	taurine ABC transporter
A3N99_RS10750	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
A3N99_RS10790	COG2378	regulation of single-species biofilm formation
A3N99_RS10795	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A3N99_RS10830	COG0300	oxidoreductase activity
A3N99_RS10885	COG1574	metal-dependent hydrolase with the TIM-barrel fold
A3N99_RS10895	COG0463	Glycosyl transferase, family 2
A3N99_RS10900	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS10925	COG0604	alcohol dehydrogenase
A3N99_RS10925	COG3321	synthase
A3N99_RS10925	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS10945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A3N99_RS10955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A3N99_RS10960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3N99_RS10980	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
A3N99_RS10990	COG1404	Belongs to the peptidase S8 family
A3N99_RS11005	COG4842	Belongs to the WXG100 family
A3N99_RS11035	COG0464	growth
A3N99_RS11090	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A3N99_RS11095	COG1169	isochorismate synthase
A3N99_RS11100	COG0789	Transcriptional regulator
A3N99_RS11105	COG1021	2,3-dihydroxybenzoate-AMP ligase
A3N99_RS11135	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A3N99_RS11140	COG1132	(ABC) transporter
A3N99_RS11145	COG1132	(ABC) transporter
A3N99_RS11145	COG2375	cellular response to nickel ion
A3N99_RS11150	COG0477	Major facilitator Superfamily
A3N99_RS11155	COG5285	phytanoyl-CoA dioxygenase
A3N99_RS11165	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A3N99_RS11170	COG0456	acetyltransferase
A3N99_RS11190	COG2837	iron assimilation
A3N99_RS11200	COG2186	Transcriptional regulator
A3N99_RS11205	COG2807	transmembrane transport
A3N99_RS11215	COG2409	Drug exporters of the RND superfamily
A3N99_RS11220	COG3629	intracellular signal transduction
A3N99_RS11225	COG1012	belongs to the aldehyde dehydrogenase family
A3N99_RS11265	COG0475	glutathione-regulated potassium exporter activity
A3N99_RS11325	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A3N99_RS11325	COG0237	dephospho-CoA kinase activity
A3N99_RS11500	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
A3N99_RS11505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A3N99_RS11505	COG0072	phenylalanine-tRNA ligase activity
A3N99_RS11515	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
A3N99_RS11520	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
A3N99_RS11525	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A3N99_RS11530	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A3N99_RS11535	COG1438	arginine binding
A3N99_RS11540	COG0137	argininosuccinate synthase activity
A3N99_RS11580	COG2835	tetraacyldisaccharide 4'-kinase activity
A3N99_RS11585	COG1309	transcriptional regulator
A3N99_RS11590	COG2094	Belongs to the DNA glycosylase MPG family
A3N99_RS11615	COG0647	UMP catabolic process
A3N99_RS11630	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A3N99_RS11650	COG0504	CTP synthase activity
A3N99_RS11655	COG0494	nUDIX hydrolase
A3N99_RS11670	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
A3N99_RS11675	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
A3N99_RS11690	COG1160	GTP binding
A3N99_RS11745	COG3976	FMN-binding domain protein
A3N99_RS11745	COG1053	succinate dehydrogenase
A3N99_RS11775	COG1960	acyl-CoA dehydrogenase activity
A3N99_RS11830	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A3N99_RS11830	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A3N99_RS11845	COG1253	flavin adenine dinucleotide binding
A3N99_RS11850	COG1253	flavin adenine dinucleotide binding
A3N99_RS11860	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
A3N99_RS11915	COG0832	Belongs to the urease beta subunit family
A3N99_RS11925	COG0830	nickel cation binding
A3N99_RS11940	COG1252	NADH dehydrogenase
A3N99_RS11950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3N99_RS11985	COG0243	molybdopterin cofactor binding
A3N99_RS11990	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A3N99_RS11995	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A3N99_RS12010	COG1546	Belongs to the CinA family
A3N99_RS12010	COG1058	Belongs to the CinA family
A3N99_RS12020	COG4977	sequence-specific DNA binding
A3N99_RS12025	COG1741	Belongs to the pirin family
A3N99_RS12045	COG1968	undecaprenyl-diphosphatase activity
A3N99_RS12050	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
A3N99_RS12075	COG0277	FAD linked oxidase domain protein
A3N99_RS12085	COG1309	transcriptional regulator
A3N99_RS12100	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
A3N99_RS12105	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A3N99_RS12135	COG4290	ribonuclease
A3N99_RS12165	COG3883	PFAM NLP P60 protein
A3N99_RS12165	COG0791	NLP P60 protein
A3N99_RS12200	COG0477	Major facilitator Superfamily
A3N99_RS12220	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A3N99_RS12225	COG0070	glutamate synthase
A3N99_RS12225	COG0069	glutamate synthase activity
A3N99_RS12225	COG0067	glutamate synthase
A3N99_RS12255	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A3N99_RS12270	COG1960	acyl-CoA dehydrogenase activity
A3N99_RS12285	COG0443	Heat shock 70 kDa protein
A3N99_RS12290	COG0596	Alpha beta hydrolase
A3N99_RS12310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A3N99_RS12320	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
A3N99_RS12345	COG2890	protein-(glutamine-N5) methyltransferase activity
A3N99_RS12410	COG1982	Orn Lys Arg decarboxylase major
A3N99_RS12470	COG2957	Belongs to the agmatine deiminase family
A3N99_RS12540	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
A3N99_RS12565	COG0288	reversible hydration of carbon dioxide
A3N99_RS12630	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
A3N99_RS12680	COG0640	Transcriptional regulator
A3N99_RS12690	COG0798	PFAM Bile acid sodium symporter
A3N99_RS12695	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A3N99_RS12705	COG0179	Fumarylacetoacetate (FAA) hydrolase
A3N99_RS12775	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
A3N99_RS12780	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
A3N99_RS12805	COG1917	Cupin 2, conserved barrel domain protein
A3N99_RS12810	COG3707	response regulator
A3N99_RS12845	COG3467	pyridoxamine 5'-phosphate
A3N99_RS12865	COG0640	Transcriptional regulator
A3N99_RS12885	COG1309	transcriptional regulator
A3N99_RS12890	COG2072	flavoprotein involved in K transport
A3N99_RS12900	COG0318	PFAM AMP-dependent synthetase and ligase
A3N99_RS12905	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A3N99_RS12910	COG0561	phosphatase activity
A3N99_RS12915	COG0673	inositol 2-dehydrogenase activity
A3N99_RS12920	COG0738	Major facilitator superfamily
A3N99_RS12930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A3N99_RS13010	COG1271	oxidase subunit
A3N99_RS13015	COG1294	oxidase, subunit
A3N99_RS13020	COG4988	ABC transporter
A3N99_RS13025	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
A3N99_RS13050	COG1946	Acyl-CoA thioesterase
A3N99_RS13060	COG2076	Multidrug Resistance protein
A3N99_RS13095	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A3N99_RS13100	COG1846	Transcriptional regulator
A3N99_RS13135	COG0483	inositol monophosphate 1-phosphatase activity
A3N99_RS13145	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A3N99_RS13150	COG0131	Imidazoleglycerol-phosphate dehydratase
A3N99_RS13155	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A3N99_RS13180	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
A3N99_RS13195	COG1309	transcriptional regulator
A3N99_RS13215	COG0583	DNA-binding transcription factor activity
A3N99_RS13220	COG0579	oxidoreductase
A3N99_RS13260	COG2755	lipolytic protein G-D-S-L family
A3N99_RS13260	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
A3N99_RS13305	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
A3N99_RS13325	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
A3N99_RS13330	COG2814	Major facilitator Superfamily
A3N99_RS13335	COG0583	DNA-binding transcription factor activity
A3N99_RS13385	COG2239	Acts as a magnesium transporter
A3N99_RS13415	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A3N99_RS13425	COG2304	oxidoreductase activity
A3N99_RS13435	COG0714	Associated with various cellular activities
A3N99_RS13445	COG0791	NLP P60 protein
A3N99_RS13445	COG3883	PFAM NLP P60 protein
A3N99_RS13455	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
A3N99_RS13460	COG1309	transcriptional regulator
A3N99_RS13485	COG0488	(ABC) transporter
A3N99_RS13500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A3N99_RS13515	COG0456	acetyltransferase
A3N99_RS13525	COG2151	metal-sulfur cluster biosynthetic enzyme
A3N99_RS13540	COG0396	ATPase activity
A3N99_RS13565	COG1131	(ABC) transporter
A3N99_RS13585	COG1309	transcriptional regulator
A3N99_RS13610	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A3N99_RS13675	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A3N99_RS13735	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A3N99_RS13795	COG0531	amino acid
A3N99_RS13850	COG2011	ABC-type metal ion transport system permease component
A3N99_RS13855	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A3N99_RS13860	COG1464	Belongs to the NlpA lipoprotein family
A3N99_RS13875	COG0477	Major facilitator Superfamily
A3N99_RS13910	COG0657	acetylesterase activity
A3N99_RS13915	COG1953	Uracil, thiamine, allantoin
A3N99_RS13925	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A3N99_RS13930	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A3N99_RS13940	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
A3N99_RS13950	COG1758	RNA polymerase activity
A3N99_RS13970	COG0284	orotidine-5'-phosphate decarboxylase activity
A3N99_RS13975	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A3N99_RS13980	COG0505	Belongs to the CarA family
A3N99_RS14000	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
A3N99_RS14020	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A3N99_RS14030	COG0006	proline dipeptidase activity
A3N99_RS14045	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
A3N99_RS14050	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
A3N99_RS14065	COG4106	trans-aconitate 2-methyltransferase activity
A3N99_RS14080	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A3N99_RS14095	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A3N99_RS14145	COG0701	Predicted permease
A3N99_RS14170	COG2272	Belongs to the type-B carboxylesterase lipase family
A3N99_RS14210	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A3N99_RS14220	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A3N99_RS14230	COG0747	negative chemotaxis
A3N99_RS14235	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A3N99_RS14250	COG2255	four-way junction helicase activity
A3N99_RS14260	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
A3N99_RS14295	COG1946	Acyl-CoA thioesterase
A3N99_RS14300	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
A3N99_RS14310	COG0438	transferase activity, transferring glycosyl groups
A3N99_RS14350	COG4762	Protein conserved in bacteria
A3N99_RS14385	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A3N99_RS14405	COG4585	Histidine kinase
A3N99_RS14460	COG3831	ATPase activity
A3N99_RS14465	COG0714	Associated with various cellular activities
A3N99_RS14470	COG2425	protein containing a von Willebrand factor type A (vWA) domain
A3N99_RS14475	COG3552	Protein containing von Willebrand factor type A (VWA) domain
A3N99_RS14480	COG4715	Zinc finger, swim domain protein
A3N99_RS14495	COG0328	RNA-DNA hybrid ribonuclease activity
A3N99_RS14580	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
A3N99_RS14630	COG5651	PPE family
A3N99_RS14660	COG1061	Type III restriction enzyme res subunit
A3N99_RS14665	COG1481	regulation of sporulation
A3N99_RS14695	COG1481	regulation of sporulation
A3N99_RS14800	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A3N99_RS14830	COG1674	ftsk spoiiie
A3N99_RS14845	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
A3N99_RS15390	COG2124	cytochrome p450
A3N99_RS15440	COG0328	RNA-DNA hybrid ribonuclease activity
A3N99_RS15445	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
A3N99_RS15445	COG1793	dna ligase
A3N99_RS15580	COG3878	Protein conserved in bacteria
A3N99_RS15630	COG1404	Belongs to the peptidase S8 family
A3N99_RS15730	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
A3N99_RS15820	COG1192	Involved in chromosome partitioning
A3N99_RS16135	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A3N99_RS16150	COG1529	Aldehyde oxidase and xanthine dehydrogenase
A3N99_RS16150	COG2080	2 iron, 2 sulfur cluster binding
A3N99_RS16165	COG0402	S-adenosylhomocysteine deaminase activity
A3N99_RS16205	COG1953	Uracil, thiamine, allantoin
A3N99_RS16215	COG1301	dicarboxylic acid transport
A3N99_RS16225	COG4266	Belongs to the allantoicase family
A3N99_RS16235	COG0596	Alpha beta hydrolase
A3N99_RS16250	COG0501	Belongs to the peptidase M48B family
A3N99_RS16265	COG0477	Major facilitator Superfamily
A3N99_RS16280	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
A3N99_RS16320	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A3N99_RS16330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A3N99_RS16370	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A3N99_RS16390	COG3253	May function as heme-dependent peroxidase
A3N99_RS16395	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
A3N99_RS16400	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
A3N99_RS16410	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
A3N99_RS16430	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
A3N99_RS16435	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A3N99_RS16440	COG0531	amino acid
A3N99_RS16445	COG0569	domain protein
A3N99_RS16475	COG0702	epimerase
A3N99_RS16490	COG0756	dUTP diphosphatase activity
A3N99_RS16535	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A3N99_RS16585	COG3220	belongs to the UPF0276 family
A3N99_RS16660	COG1388	LysM domain
A3N99_RS16675	COG1960	acyl-CoA dehydrogenase activity
A3N99_RS16685	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A3N99_RS16705	COG1196	nuclear chromosome segregation
A3N99_RS16725	COG1126	abc transporter atp-binding protein
A3N99_RS16730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A3N99_RS16735	COG0765	amino acid transport
A3N99_RS16740	COG0765	amino acid transport
A3N99_RS16790	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
A3N99_RS16795	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
A3N99_RS16810	COG1842	Phage shock protein A
A3N99_RS16815	COG1396	sequence-specific DNA binding
A3N99_RS16825	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS16835	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
A3N99_RS16890	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A3N99_RS16895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A3N99_RS16910	COG3214	Protein conserved in bacteria
A3N99_RS16960	COG0659	secondary active sulfate transmembrane transporter activity
A3N99_RS16970	COG0686	Belongs to the AlaDH PNT family
A3N99_RS17055	COG2977	Belongs to the P-Pant transferase superfamily
A3N99_RS17060	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A3N99_RS17080	COG1960	acyl-CoA dehydrogenase activity
A3N99_RS17085	COG1960	acyl-CoA dehydrogenase activity
A3N99_RS17090	COG1024	Enoyl-CoA hydratase
A3N99_RS17115	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A3N99_RS17140	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A3N99_RS17140	COG1017	nitric oxide dioxygenase activity
A3N99_RS17145	COG1959	2 iron, 2 sulfur cluster binding
A3N99_RS17190	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A3N99_RS17190	COG1648	precorrin-2 dehydrogenase activity
A3N99_RS17215	COG3321	synthase
A3N99_RS17215	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS17215	COG0604	alcohol dehydrogenase
A3N99_RS17275	COG0579	oxidoreductase
A3N99_RS17295	COG1492	cobalamin metabolic process
A3N99_RS17305	COG1376	ErfK ybiS ycfS ynhG family protein
A3N99_RS17330	COG0750	zinc metalloprotease
A3N99_RS17355	COG0820	rRNA (adenine-C2-)-methyltransferase activity
A3N99_RS17395	COG0412	Dienelactone hydrolase
A3N99_RS17420	COG0528	UMP kinase activity
A3N99_RS17425	COG3973	AAA domain
A3N99_RS17440	COG2723	6-phospho-beta-galactosidase activity
A3N99_RS17475	COG1309	transcriptional regulator
A3N99_RS17515	COG0583	DNA-binding transcription factor activity
A3N99_RS17545	COG0792	nuclease activity
A3N99_RS17620	COG0336	Belongs to the RNA methyltransferase TrmD family
A3N99_RS17660	COG1686	Belongs to the peptidase S11 family
A3N99_RS17680	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
A3N99_RS17700	COG1304	FMN binding
A3N99_RS17750	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
A3N99_RS17755	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
A3N99_RS17775	COG0571	ribonuclease III activity
A3N99_RS17785	COG3599	regulation of cell shape
A3N99_RS17830	COG0742	ribosomal rna small subunit methyltransferase
A3N99_RS17835	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
A3N99_RS17850	COG0657	acetylesterase activity
A3N99_RS17855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3N99_RS17875	COG2124	cytochrome p450
A3N99_RS17890	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A3N99_RS17895	COG1461	Dihydroxyacetone kinase
A3N99_RS17905	COG1024	Enoyl-CoA hydratase
A3N99_RS17930	COG1181	Belongs to the D-alanine--D-alanine ligase family
A3N99_RS17935	COG0626	cystathionine gamma-synthase activity
A3N99_RS17940	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
A3N99_RS17950	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
A3N99_RS18020	COG0179	Fumarylacetoacetate (FAA) hydrolase
A3N99_RS18035	COG2271	Major facilitator Superfamily
A3N99_RS18070	COG0583	DNA-binding transcription factor activity
A3N99_RS18080	COG0778	Nitroreductase
A3N99_RS18095	COG1309	transcriptional regulator
A3N99_RS18100	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A3N99_RS18105	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A3N99_RS18110	COG2124	cytochrome p450
A3N99_RS18185	COG0440	acetolactate synthase activity
A3N99_RS18200	COG1748	Saccharopine dehydrogenase
A3N99_RS18205	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A3N99_RS18225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A3N99_RS18245	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A3N99_RS18255	COG2272	Belongs to the type-B carboxylesterase lipase family
A3N99_RS18270	COG0745	RESPONSE REGULATOR receiver
A3N99_RS18275	COG2205	protein histidine kinase activity
A3N99_RS18300	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
A3N99_RS18330	COG1024	Enoyl-CoA hydratase
A3N99_RS18335	COG0778	Nitroreductase
A3N99_RS18345	COG2252	PERMEase
A3N99_RS18385	COG2197	response regulator
A3N99_RS18390	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
A3N99_RS18400	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A3N99_RS18425	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
A3N99_RS18440	COG1309	transcriptional regulator
A3N99_RS18465	COG0110	maltose O-acetyltransferase activity
A3N99_RS18470	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A3N99_RS18495	COG1119	ATPase activity
A3N99_RS18505	COG2364	Membrane
A3N99_RS18510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3N99_RS18525	COG4607	ABC-type enterochelin transport system periplasmic component
A3N99_RS18575	COG1064	alcohol dehydrogenase
A3N99_RS18595	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A3N99_RS18600	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS18675	COG0477	Major facilitator Superfamily
A3N99_RS18695	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS18725	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS18750	COG1335	isochorismatase
A3N99_RS18760	COG2855	membrane
A3N99_RS18770	COG0318	PFAM AMP-dependent synthetase and ligase
A3N99_RS18785	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS18795	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS18800	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A3N99_RS18855	COG2272	Belongs to the type-B carboxylesterase lipase family
A3N99_RS18860	COG2272	Belongs to the type-B carboxylesterase lipase family
A3N99_RS18870	COG0183	Belongs to the thiolase family
A3N99_RS18905	COG1309	transcriptional regulator
A3N99_RS18935	COG0789	Transcriptional regulator
A3N99_RS18945	COG0028	Belongs to the TPP enzyme family
A3N99_RS18970	COG2177	Part of the ABC transporter FtsEX involved in
A3N99_RS18975	COG2884	Cell division ATP-binding protein ftsE
A3N99_RS18985	COG0668	transmembrane transport
A3N99_RS19025	COG0483	inositol monophosphate 1-phosphatase activity
A3N99_RS19030	COG1960	acyl-CoA dehydrogenase activity
A3N99_RS19035	COG1960	acyl-CoA dehydrogenase activity
A3N99_RS19050	COG0318	PFAM AMP-dependent synthetase and ligase
A3N99_RS19060	COG0542	response to heat
A3N99_RS19105	COG3480	Lon protease (S16) C-terminal proteolytic domain
A3N99_RS19110	COG3011	Protein conserved in bacteria
A3N99_RS19125	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A3N99_RS19130	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A3N99_RS19135	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A3N99_RS19170	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A3N99_RS19170	COG0475	glutathione-regulated potassium exporter activity
A3N99_RS19185	COG0596	Alpha beta hydrolase
A3N99_RS19200	COG0745	RESPONSE REGULATOR receiver
A3N99_RS19210	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A3N99_RS19210	COG2146	nitrite reductase [NAD(P)H] activity
A3N99_RS19215	COG2223	nitrite transmembrane transporter activity
A3N99_RS19255	COG0513	Belongs to the DEAD box helicase family
A3N99_RS19270	COG0406	alpha-ribazole phosphatase activity
A3N99_RS19280	COG0456	acetyltransferase
A3N99_RS19290	COG1597	lipid kinase activity
A3N99_RS19305	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
A3N99_RS19315	COG1595	DNA-templated transcription, initiation
A3N99_RS19325	COG2135	peptidase activity
A3N99_RS19330	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
A3N99_RS19335	COG1162	GTPase activity
A3N99_RS19370	COG1309	transcriptional regulator
A3N99_RS19375	COG0653	protein targeting
A3N99_RS19385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3N99_RS19390	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A3N99_RS19400	COG1309	transcriptional regulator
A3N99_RS19415	COG5401	PFAM Sporulation and spore germination
A3N99_RS19420	COG5002	protein histidine kinase activity
A3N99_RS19430	COG0318	PFAM AMP-dependent synthetase and ligase
A3N99_RS19435	COG1285	pathogenesis
A3N99_RS19475	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A3N99_RS19480	COG0531	amino acid
A3N99_RS19490	COG1482	cell wall glycoprotein biosynthetic process
A3N99_RS19520	COG0391	Required for morphogenesis under gluconeogenic growth conditions
A3N99_RS19525	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
A3N99_RS19525	COG0778	Nitroreductase
A3N99_RS19540	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A3N99_RS19555	COG1316	TRANSCRIPTIONal
A3N99_RS19575	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A3N99_RS19585	COG2175	clavaminate synthase activity
A3N99_RS19610	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
A3N99_RS19610	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
A3N99_RS19620	COG0318	PFAM AMP-dependent synthetase and ligase
A3N99_RS19635	COG1309	transcriptional regulator
A3N99_RS19660	COG0582	viral genome integration into host DNA
A3N99_RS19690	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A3N99_RS19700	COG0424	maF-like protein
A3N99_RS19715	COG2226	methyltransferase
A3N99_RS19725	COG3265	gluconokinase activity
A3N99_RS19745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3N99_RS19755	COG1733	regulation of RNA biosynthetic process
A3N99_RS19780	COG4770	biotin carboxylase activity
A3N99_RS19815	COG1012	belongs to the aldehyde dehydrogenase family
A3N99_RS19820	COG1309	transcriptional regulator
A3N99_RS19825	COG1201	RNA secondary structure unwinding
A3N99_RS19840	COG0564	pseudouridine synthase activity
A3N99_RS19860	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
A3N99_RS19860	COG1473	amidohydrolase
A3N99_RS19875	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A3N99_RS19890	COG0791	NLP P60 protein
A3N99_RS19890	COG3883	PFAM NLP P60 protein
A3N99_RS19935	COG2009	succinate dehydrogenase
A3N99_RS19950	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A3N99_RS19955	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A3N99_RS19960	COG1595	DNA-templated transcription, initiation
A3N99_RS19970	COG1686	Belongs to the peptidase S11 family
A3N99_RS19985	COG0708	Exodeoxyribonuclease III
A3N99_RS20045	COG1733	regulation of RNA biosynthetic process
A3N99_RS20050	COG2910	NAD(P)H-binding
A3N99_RS20055	COG0842	Transport permease protein
A3N99_RS20055	COG1716	ATPase activity
A3N99_RS20055	COG1131	(ABC) transporter
A3N99_RS20060	COG1357	PFAM Pentapeptide repeats (8 copies)
A3N99_RS20065	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A3N99_RS20080	COG1309	transcriptional regulator
A3N99_RS20145	COG0519	Catalyzes the synthesis of GMP from XMP
A3N99_RS20145	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A3N99_RS20155	COG0516	GMP reductase activity
A3N99_RS20200	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
A3N99_RS20215	COG0456	acetyltransferase
A3N99_RS20235	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A3N99_RS20240	COG0076	glutamate decarboxylase activity
A3N99_RS20250	COG2267	carboxylic ester hydrolase activity
A3N99_RS20255	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A3N99_RS20280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3N99_RS20290	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A3N99_RS20295	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A3N99_RS20330	COG1404	Belongs to the peptidase S8 family
A3N99_RS20360	COG2267	carboxylic ester hydrolase activity
A3N99_RS20415	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
A3N99_RS20420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A3N99_RS20430	COG2268	Band 7 protein
A3N99_RS20440	COG1088	dTDP-glucose 4,6-dehydratase activity
A3N99_RS20445	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
A3N99_RS20490	COG0616	signal peptide processing
A3N99_RS20505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3N99_RS20525	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
A3N99_RS20535	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
A3N99_RS20545	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A3N99_RS20560	COG2272	Belongs to the type-B carboxylesterase lipase family
A3N99_RS20585	COG0477	Major facilitator Superfamily
A3N99_RS20600	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
A3N99_RS20615	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
A3N99_RS20640	COG0088	Forms part of the polypeptide exit tunnel
A3N99_RS20645	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
A3N99_RS20650	COG0051	transcription antitermination factor activity, RNA binding
A3N99_RS20655	COG0259	pyridoxamine-phosphate oxidase activity
A3N99_RS20685	COG0531	amino acid
A3N99_RS20715	COG0535	radical SAM domain protein
A3N99_RS20740	COG1834	amidinotransferase
A3N99_RS20745	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A3N99_RS20750	COG0531	amino acid
A3N99_RS20795	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
A3N99_RS20800	COG1309	transcriptional regulator
A3N99_RS20825	COG1024	Enoyl-CoA hydratase
A3N99_RS20840	COG1960	acyl-CoA dehydrogenase activity
A3N99_RS20870	COG1113	amino acid transport
A3N99_RS20885	COG0085	RNA polymerase activity
A3N99_RS20890	COG0243	molybdopterin cofactor binding
A3N99_RS20945	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A3N99_RS20960	COG0277	FAD linked oxidase domain protein
A3N99_RS20980	COG4941	Belongs to the sigma-70 factor family
A3N99_RS21015	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A3N99_RS21055	COG0783	Belongs to the Dps family
A3N99_RS21060	COG0693	protein deglycase activity
A3N99_RS21105	COG1404	Belongs to the peptidase S8 family
A3N99_RS21125	COG1280	lysine exporter protein (LysE YggA)
A3N99_RS21195	COG0501	Belongs to the peptidase M48B family
A3N99_RS21200	COG0142	geranyltranstransferase activity
A3N99_RS21205	COG0644	oxidoreductase
A3N99_RS21215	COG0438	transferase activity, transferring glycosyl groups
A3N99_RS21235	COG4948	Mandelate Racemase Muconate Lactonizing
A3N99_RS21255	COG3706	GGDEF domain
A3N99_RS21270	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A3N99_RS21280	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
A3N99_RS21285	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS21290	COG4221	oxidoreductase activity
A3N99_RS21335	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A3N99_RS21340	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A3N99_RS21375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A3N99_RS21420	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A3N99_RS21430	COG0785	Cytochrome C biogenesis protein
A3N99_RS21435	COG0386	Belongs to the glutathione peroxidase family
A3N99_RS21440	COG0406	alpha-ribazole phosphatase activity
A3N99_RS21455	COG3590	peptidase
A3N99_RS21505	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A3N99_RS21505	COG1648	precorrin-2 dehydrogenase activity
A3N99_RS21530	COG2030	dehydratase
A3N99_RS21555	COG2070	2-Nitropropane dioxygenase
A3N99_RS21575	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A3N99_RS21580	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A3N99_RS21665	COG2072	flavoprotein involved in K transport
A3N99_RS21690	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A3N99_RS21740	COG2072	flavoprotein involved in K transport
A3N99_RS21755	COG2072	flavoprotein involved in K transport
A3N99_RS21760	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS21765	COG0657	acetylesterase activity
A3N99_RS21770	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A3N99_RS21780	COG0745	RESPONSE REGULATOR receiver
A3N99_RS21785	COG5002	protein histidine kinase activity
A3N99_RS21795	COG2072	flavoprotein involved in K transport
A3N99_RS21810	COG0300	oxidoreductase activity
A3N99_RS21865	COG2814	Major facilitator Superfamily
A3N99_RS21960	COG2733	membrane
A3N99_RS21970	COG2326	polyphosphate kinase activity
A3N99_RS21975	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A3N99_RS22010	COG2224	Isocitrate lyase
A3N99_RS22050	COG2226	methyltransferase
A3N99_RS22105	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A3N99_RS22140	COG0667	Aldo Keto reductase
A3N99_RS22160	COG4552	Acetyltransferase involved in intracellular survival and related
A3N99_RS22165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3N99_RS22190	COG1505	serine-type exopeptidase activity
A3N99_RS22210	COG1073	alpha beta
A3N99_RS22215	COG2326	polyphosphate kinase activity
A3N99_RS22230	COG2223	nitrite transmembrane transporter activity
A3N99_RS22235	COG0640	Transcriptional regulator
A3N99_RS22265	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
A3N99_RS22285	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A3N99_RS22310	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A3N99_RS22320	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A3N99_RS22325	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS22335	COG1960	acyl-CoA dehydrogenase activity
A3N99_RS22340	COG1960	acyl-CoA dehydrogenase activity
A3N99_RS22345	COG0318	PFAM AMP-dependent synthetase and ligase
A3N99_RS22355	COG2070	2-Nitropropane dioxygenase
A3N99_RS22365	COG1024	Enoyl-CoA hydratase
A3N99_RS22375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3N99_RS22410	COG4638	Rieske (2fe-2S)
A3N99_RS22450	COG0175	sulfate reduction
A3N99_RS22520	COG2814	Major facilitator Superfamily
A3N99_RS22530	COG0351	phosphomethylpyrimidine kinase
A3N99_RS22540	COG1252	NADH dehydrogenase
A3N99_RS22550	COG1309	transcriptional regulator
A3N99_RS22560	COG1012	belongs to the aldehyde dehydrogenase family
A3N99_RS22595	COG0494	nUDIX hydrolase
A3N99_RS22605	COG2234	aminopeptidase activity
A3N99_RS22610	COG2234	aminopeptidase activity
A3N99_RS22620	COG1131	(ABC) transporter
A3N99_RS22625	COG2022	thiamine diphosphate biosynthetic process
A3N99_RS22660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A3N99_RS22665	COG0515	serine threonine protein kinase
A3N99_RS22670	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
A3N99_RS22700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3N99_RS22705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3N99_RS22710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3N99_RS22715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3N99_RS22725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A3N99_RS22730	COG1126	abc transporter atp-binding protein
A3N99_RS22735	COG0765	amino acid transport
A3N99_RS22770	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
A3N99_RS22790	COG0415	Belongs to the DNA photolyase family
A3N99_RS22795	COG1090	epimerase
A3N99_RS22805	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A3N99_RS22820	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A3N99_RS22830	COG1595	DNA-templated transcription, initiation
A3N99_RS22855	COG1994	Peptidase M50
A3N99_RS22875	COG0586	Pfam SNARE associated Golgi protein
A3N99_RS22905	COG4221	oxidoreductase activity
A3N99_RS22925	COG0542	response to heat
A3N99_RS22950	COG0789	Transcriptional regulator
A3N99_RS22960	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A3N99_RS23035	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A3N99_RS23035	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
A3N99_RS23055	COG2259	Doxx family
A3N99_RS23075	COG2181	nitrate reductase activity
A3N99_RS23075	COG0247	lactate metabolic process
A3N99_RS23085	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A3N99_RS23125	COG3345	alpha-galactosidase
A3N99_RS23130	COG1262	PFAM Formylglycine-generating sulfatase enzyme
A3N99_RS23135	COG1305	Transglutaminase-like
A3N99_RS23150	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A3N99_RS23230	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A3N99_RS23305	COG1012	belongs to the aldehyde dehydrogenase family
A3N99_RS23370	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS23375	COG1960	acyl-CoA dehydrogenase activity
A3N99_RS23390	COG3268	Saccharopine dehydrogenase
A3N99_RS23395	COG0318	PFAM AMP-dependent synthetase and ligase
A3N99_RS23400	COG3285	dna ligase
A3N99_RS23400	COG1793	dna ligase
A3N99_RS23410	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A3N99_RS23415	COG0318	PFAM AMP-dependent synthetase and ligase
A3N99_RS23455	COG1309	transcriptional regulator
A3N99_RS23460	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
A3N99_RS23475	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A3N99_RS23480	COG1984	allophanate hydrolase subunit 2
A3N99_RS23545	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
A3N99_RS23550	COG1802	Transcriptional regulator
A3N99_RS23580	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A3N99_RS23590	COG0473	3-isopropylmalate dehydrogenase activity
A3N99_RS23605	COG1053	succinate dehydrogenase
A3N99_RS23625	COG0640	Transcriptional regulator
A3N99_RS23675	COG2318	DinB family
A3N99_RS23680	COG1960	acyl-CoA dehydrogenase activity
A3N99_RS23705	COG0183	Belongs to the thiolase family
A3N99_RS23710	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS23715	COG2030	dehydratase
A3N99_RS23730	COG0659	secondary active sulfate transmembrane transporter activity
A3N99_RS23735	COG1309	transcriptional regulator
A3N99_RS23740	COG0861	Integral membrane protein TerC family
A3N99_RS23765	COG0318	PFAM AMP-dependent synthetase and ligase
A3N99_RS23780	COG1472	Belongs to the glycosyl hydrolase 3 family
A3N99_RS23785	COG4941	Belongs to the sigma-70 factor family
A3N99_RS23840	COG3119	arylsulfatase activity
A3N99_RS23855	COG4981	capsule polysaccharide biosynthetic process
A3N99_RS23890	COG0438	transferase activity, transferring glycosyl groups
A3N99_RS23945	COG2197	response regulator
A3N99_RS23950	COG3850	Histidine kinase
A3N99_RS23970	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
A3N99_RS24000	COG2409	Drug exporters of the RND superfamily
A3N99_RS24045	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A3N99_RS24055	COG2197	response regulator
A3N99_RS24085	COG2353	YceI-like domain
A3N99_RS24105	COG2409	Drug exporters of the RND superfamily
A3N99_RS24120	COG4552	Acetyltransferase involved in intracellular survival and related
A3N99_RS24125	COG1832	CoA-binding protein
A3N99_RS24140	COG3590	peptidase
A3N99_RS24145	COG1376	ErfK ybiS ycfS ynhG family protein
A3N99_RS24150	COG1960	acyl-CoA dehydrogenase activity
A3N99_RS24160	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A3N99_RS24170	COG1937	Protein conserved in bacteria
A3N99_RS24200	COG4122	O-methyltransferase activity
A3N99_RS24215	COG2267	carboxylic ester hydrolase activity
A3N99_RS24245	COG1704	LemA family
A3N99_RS24255	COG0318	PFAM AMP-dependent synthetase and ligase
A3N99_RS24310	COG1024	Enoyl-CoA hydratase
A3N99_RS24315	COG1802	Transcriptional regulator
A3N99_RS24325	COG2267	carboxylic ester hydrolase activity
A3N99_RS24330	COG1309	transcriptional regulator
A3N99_RS24360	COG0435	Glutathione S-transferase
A3N99_RS24400	COG1024	Enoyl-CoA hydratase
A3N99_RS24410	COG2211	Major facilitator Superfamily
A3N99_RS24415	COG2365	Tyrosine phosphatase family
A3N99_RS24480	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS24485	COG1012	belongs to the aldehyde dehydrogenase family
A3N99_RS24500	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A3N99_RS24505	COG1960	acyl-CoA dehydrogenase activity
A3N99_RS24510	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A3N99_RS24525	COG2813	Specifically methylates the guanine in position
A3N99_RS24540	COG1396	sequence-specific DNA binding
A3N99_RS24540	COG3800	Transcriptional regulator
A3N99_RS24550	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
A3N99_RS24590	COG0318	PFAM AMP-dependent synthetase and ligase
A3N99_RS24650	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
A3N99_RS24660	COG0129	dihydroxy-acid dehydratase activity
A3N99_RS24685	COG2186	Transcriptional regulator
A3N99_RS24715	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A3N99_RS24720	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A3N99_RS24750	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS24790	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS24810	COG0318	PFAM AMP-dependent synthetase and ligase
A3N99_RS24815	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A3N99_RS24820	COG1136	(ABC) transporter
A3N99_RS24830	COG1104	cysteine desulfurase activity
A3N99_RS24890	COG1309	transcriptional regulator
A3N99_RS24895	COG1819	glycosyl
A3N99_RS24940	COG1819	glycosyl
A3N99_RS25050	COG3263	regulation of cellular component size
A3N99_RS25125	COG1595	DNA-templated transcription, initiation
A3N99_RS25135	COG0783	Belongs to the Dps family
A3N99_RS25180	COG1252	NADH dehydrogenase
A3N99_RS25200	COG1937	Protein conserved in bacteria
A3N99_RS25295	COG2140	Oxalate decarboxylase
A3N99_RS25320	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
A3N99_RS25340	COG1376	ErfK ybiS ycfS ynhG family protein
A3N99_RS25370	COG2030	dehydratase
A3N99_RS25375	COG0488	(ABC) transporter
A3N99_RS25380	COG3757	hydrolase, family 25
A3N99_RS25440	COG0583	DNA-binding transcription factor activity
A3N99_RS25450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3N99_RS25465	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A3N99_RS25470	COG3757	hydrolase, family 25
A3N99_RS25495	COG2205	protein histidine kinase activity
A3N99_RS25500	COG0745	RESPONSE REGULATOR receiver
A3N99_RS25540	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A3N99_RS25555	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
A3N99_RS25565	COG1335	isochorismatase
A3N99_RS25585	COG0629	single-stranded DNA binding
A3N99_RS25600	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A3N99_RS25630	COG1260	myo-inositol-1-phosphate synthase
A3N99_RS25635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3N99_RS25640	COG1113	amino acid transport
A3N99_RS25655	COG1309	transcriptional regulator
A3N99_RS25660	COG1028	Short-chain dehydrogenase reductase Sdr
A3N99_RS25675	COG0508	dehydrogenase complex catalyzes the overall conversion of
A3N99_RS25680	COG0022	dehydrogenase e1 component
A3N99_RS25695	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
A3N99_RS25700	COG2311	Membrane
A3N99_RS25765	COG0617	tRNA 3'-terminal CCA addition
A3N99_RS25785	COG1595	DNA-templated transcription, initiation
A3N99_RS25805	COG3409	Peptidoglycan-binding domain 1 protein
A3N99_RS25805	COG0860	N-Acetylmuramoyl-L-alanine amidase
A3N99_RS25815	COG2124	cytochrome p450
A3N99_RS25825	COG1309	transcriptional regulator
A3N99_RS25845	COG1192	Involved in chromosome partitioning
A3N99_RS25850	COG0357	Ribosomal RNA small subunit methyltransferase G
A3N99_RS25860	COG0706	membrane insertase activity