locus-tag	class	description
A3O06_RS00010	COG0592	DNA-directed DNA polymerase activity
A3O06_RS00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
A3O06_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
A3O06_RS00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
A3O06_RS00030	COG0187	DNA topoisomerase II activity
A3O06_RS00120	COG2814	Major facilitator Superfamily
A3O06_RS00125	COG0583	DNA-binding transcription factor activity
A3O06_RS00140	COG0457	Tetratricopeptide repeat
A3O06_RS00140	COG0705	Rhomboid family
A3O06_RS00175	COG0515	serine threonine protein kinase
A3O06_RS00175	COG2815	serine threonine protein kinase
A3O06_RS00180	COG0515	serine threonine protein kinase
A3O06_RS00185	COG0768	penicillin binding
A3O06_RS00200	COG1716	ATPase activity
A3O06_RS00205	COG1716	ATPase activity
A3O06_RS00230	COG0754	glutathionylspermidine amidase activity
A3O06_RS00240	COG1309	transcriptional regulator
A3O06_RS00260	COG4842	Belongs to the WXG100 family
A3O06_RS00280	COG0590	tRNA wobble adenosine to inosine editing
A3O06_RS00290	COG0583	DNA-binding transcription factor activity
A3O06_RS00295	COG1643	Atp-dependent helicase
A3O06_RS00300	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS00330	COG1960	acyl-CoA dehydrogenase activity
A3O06_RS00385	COG0346	lactoylglutathione lyase activity
A3O06_RS00390	COG1414	Transcriptional regulator
A3O06_RS00410	COG1053	succinate dehydrogenase
A3O06_RS00440	COG1785	Belongs to the alkaline phosphatase family
A3O06_RS00460	COG0070	glutamate synthase
A3O06_RS00460	COG0069	glutamate synthase activity
A3O06_RS00460	COG0067	glutamate synthase
A3O06_RS00490	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A3O06_RS00490	COG1796	DNA polymerase
A3O06_RS00500	COG2072	flavoprotein involved in K transport
A3O06_RS00510	COG2124	cytochrome p450
A3O06_RS00550	COG2372	response to copper ion
A3O06_RS00600	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A3O06_RS00615	COG5001	Diguanylate cyclase
A3O06_RS00615	COG5002	protein histidine kinase activity
A3O06_RS00615	COG3447	MASE1 domain protein
A3O06_RS00625	COG1528	Iron-storage protein
A3O06_RS00630	COG1528	Iron-storage protein
A3O06_RS00635	COG1316	TRANSCRIPTIONal
A3O06_RS00665	COG0406	alpha-ribazole phosphatase activity
A3O06_RS00670	COG0028	Belongs to the TPP enzyme family
A3O06_RS00680	COG2072	flavoprotein involved in K transport
A3O06_RS00690	COG2072	flavoprotein involved in K transport
A3O06_RS00710	COG1285	pathogenesis
A3O06_RS00760	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A3O06_RS00760	COG2146	nitrite reductase [NAD(P)H] activity
A3O06_RS00770	COG4133	protoheme IX ABC transporter activity
A3O06_RS00775	COG2070	2-Nitropropane dioxygenase
A3O06_RS00780	COG1942	4-Oxalocrotonate Tautomerase
A3O06_RS00785	COG0583	DNA-binding transcription factor activity
A3O06_RS00800	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS00805	COG0204	Acyl-transferase
A3O06_RS00815	COG0561	phosphatase activity
A3O06_RS00835	COG1216	Glycosyl transferase, family 2
A3O06_RS00840	COG0671	phosphoesterase, PA-phosphatase related
A3O06_RS00845	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
A3O06_RS00850	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
A3O06_RS00870	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
A3O06_RS00875	COG0318	PFAM AMP-dependent synthetase and ligase
A3O06_RS00880	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A3O06_RS00880	COG3321	synthase
A3O06_RS00880	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
A3O06_RS00885	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A3O06_RS00935	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS00940	COG0277	FAD linked oxidase domain protein
A3O06_RS00955	COG2376	Dihydroxyacetone kinase
A3O06_RS00960	COG2267	carboxylic ester hydrolase activity
A3O06_RS00965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3O06_RS00970	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A3O06_RS00985	COG0671	phosphoesterase, PA-phosphatase related
A3O06_RS00995	COG1216	Glycosyl transferase, family 2
A3O06_RS01055	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A3O06_RS01060	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A3O06_RS01300	COG2304	oxidoreductase activity
A3O06_RS01595	COG4974	Belongs to the 'phage' integrase family
A3O06_RS01645	COG1960	acyl-CoA dehydrogenase activity
A3O06_RS01660	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS01680	COG1174	glycine betaine transport
A3O06_RS01695	COG0287	Prephenate dehydrogenase
A3O06_RS01705	COG0590	tRNA wobble adenosine to inosine editing
A3O06_RS01730	COG0343	queuine tRNA-ribosyltransferase activity
A3O06_RS01740	COG0765	amino acid transport
A3O06_RS01745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A3O06_RS01750	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A3O06_RS01755	COG1793	dna ligase
A3O06_RS01785	COG2271	Major facilitator Superfamily
A3O06_RS01790	COG0604	alcohol dehydrogenase
A3O06_RS01840	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS01875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3O06_RS01900	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A3O06_RS01910	COG0148	phosphopyruvate hydratase activity
A3O06_RS01940	COG0860	N-Acetylmuramoyl-L-alanine amidase
A3O06_RS01955	COG1492	cobalamin metabolic process
A3O06_RS01980	COG1960	acyl-CoA dehydrogenase activity
A3O06_RS01995	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
A3O06_RS02025	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A3O06_RS02070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3O06_RS02080	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A3O06_RS02110	COG2070	2-Nitropropane dioxygenase
A3O06_RS02145	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A3O06_RS02150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A3O06_RS02155	COG2971	BadF BadG BcrA BcrD
A3O06_RS02160	COG2814	Major facilitator Superfamily
A3O06_RS02180	COG3572	ergothioneine biosynthetic process
A3O06_RS02185	COG1262	PFAM Formylglycine-generating sulfatase enzyme
A3O06_RS02190	COG0121	glutamine amidotransferase
A3O06_RS02195	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
A3O06_RS02200	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A3O06_RS02225	COG0183	Belongs to the thiolase family
A3O06_RS02230	COG2030	dehydratase
A3O06_RS02235	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS02240	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A3O06_RS02250	COG1695	Transcriptional regulator
A3O06_RS02260	COG0475	glutathione-regulated potassium exporter activity
A3O06_RS02260	COG0569	domain protein
A3O06_RS02280	COG0714	Associated with various cellular activities
A3O06_RS02320	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A3O06_RS02325	COG1074	ATP-dependent DNA helicase activity
A3O06_RS02330	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
A3O06_RS02340	COG2755	lipolytic protein G-D-S-L family
A3O06_RS02370	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A3O06_RS02375	COG1408	metallophosphoesterase
A3O06_RS02380	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
A3O06_RS02410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3O06_RS02450	COG2945	thiolester hydrolase activity
A3O06_RS02450	COG0596	Alpha beta hydrolase
A3O06_RS02465	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A3O06_RS02470	COG0747	negative chemotaxis
A3O06_RS02480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A3O06_RS02560	COG1695	Transcriptional regulator
A3O06_RS02565	COG0657	acetylesterase activity
A3O06_RS02570	COG1902	pentaerythritol trinitrate reductase activity
A3O06_RS02575	COG1111	helicase
A3O06_RS02575	COG1205	dead DEAH box helicase
A3O06_RS02580	COG1278	Cold shock
A3O06_RS02590	COG1754	DNA topoisomerase type I activity
A3O06_RS02590	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A3O06_RS02620	COG2267	carboxylic ester hydrolase activity
A3O06_RS02730	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
A3O06_RS02825	COG0740	serine-type endopeptidase activity
A3O06_RS03060	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A3O06_RS03095	COG2027	D-alanyl-D-alanine carboxypeptidase
A3O06_RS03125	COG1063	alcohol dehydrogenase
A3O06_RS03135	COG2267	carboxylic ester hydrolase activity
A3O06_RS03145	COG1309	transcriptional regulator
A3O06_RS03160	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3O06_RS03205	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
A3O06_RS03215	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
A3O06_RS03235	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
A3O06_RS03240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A3O06_RS03280	COG4977	sequence-specific DNA binding
A3O06_RS03285	COG1194	a g-specific adenine glycosylase
A3O06_RS03295	COG1316	TRANSCRIPTIONal
A3O06_RS03305	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
A3O06_RS03315	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A3O06_RS03335	COG1329	Transcriptional regulator
A3O06_RS03340	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
A3O06_RS03350	COG0215	cysteine-tRNA ligase activity
A3O06_RS03360	COG0584	glycerophosphoryl diester phosphodiesterase
A3O06_RS03370	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A3O06_RS03375	COG1120	ATPase activity
A3O06_RS03380	COG0803	Belongs to the bacterial solute-binding protein 9 family
A3O06_RS03390	COG1309	transcriptional regulator
A3O06_RS03395	COG1960	acyl-CoA dehydrogenase activity
A3O06_RS03405	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A3O06_RS03415	COG0346	lactoylglutathione lyase activity
A3O06_RS03455	COG1960	acyl-CoA dehydrogenase activity
A3O06_RS03460	COG1960	acyl-CoA dehydrogenase activity
A3O06_RS03465	COG1960	acyl-CoA dehydrogenase activity
A3O06_RS03470	COG0318	PFAM AMP-dependent synthetase and ligase
A3O06_RS03475	COG1960	acyl-CoA dehydrogenase activity
A3O06_RS03490	COG0183	Belongs to the thiolase family
A3O06_RS03520	COG1024	Enoyl-CoA hydratase
A3O06_RS03525	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS03530	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS03550	COG0183	Belongs to the thiolase family
A3O06_RS03560	COG1960	acyl-CoA dehydrogenase activity
A3O06_RS03565	COG1960	acyl-CoA dehydrogenase activity
A3O06_RS03570	COG2030	dehydratase
A3O06_RS03595	COG2030	dehydratase
A3O06_RS03600	COG1053	succinate dehydrogenase
A3O06_RS03610	COG3971	2-oxopent-4-enoate hydratase activity
A3O06_RS03745	COG0464	growth
A3O06_RS03755	COG1674	ftsk spoiiie
A3O06_RS03790	COG0651	ATP synthesis coupled electron transport
A3O06_RS03800	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A3O06_RS03800	COG2111	Na H antiporter
A3O06_RS03815	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3O06_RS03835	COG0647	UMP catabolic process
A3O06_RS03860	COG4221	oxidoreductase activity
A3O06_RS03880	COG0459	protein refolding
A3O06_RS03895	COG0714	Associated with various cellular activities
A3O06_RS03945	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A3O06_RS03960	COG4842	Belongs to the WXG100 family
A3O06_RS04000	COG0745	RESPONSE REGULATOR receiver
A3O06_RS04005	COG5002	protein histidine kinase activity
A3O06_RS04005	COG5000	phosphorelay sensor kinase activity
A3O06_RS04010	COG0537	adenosine 5'-monophosphoramidase activity
A3O06_RS04015	COG0697	spore germination
A3O06_RS04025	COG0596	Alpha beta hydrolase
A3O06_RS04055	COG0436	Aminotransferase
A3O06_RS04065	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A3O06_RS04090	COG0477	Major facilitator Superfamily
A3O06_RS04095	COG0386	Belongs to the glutathione peroxidase family
A3O06_RS04105	COG3573	Dehydrogenase
A3O06_RS04115	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A3O06_RS04130	COG2837	iron assimilation
A3O06_RS04210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A3O06_RS04220	COG0601	transmembrane transport
A3O06_RS04225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A3O06_RS04260	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
A3O06_RS04270	COG0354	folic acid binding
A3O06_RS04320	COG2897	thiosulfate sulfurtransferase activity
A3O06_RS04340	COG0745	RESPONSE REGULATOR receiver
A3O06_RS04360	COG0581	inorganic phosphate transmembrane transporter activity
A3O06_RS04365	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A3O06_RS04370	COG0604	alcohol dehydrogenase
A3O06_RS04425	COG1250	3-hydroxyacyl-CoA dehydrogenase
A3O06_RS04450	COG0697	spore germination
A3O06_RS04470	COG0442	prolyl-tRNA aminoacylation
A3O06_RS04475	COG2814	Major facilitator Superfamily
A3O06_RS04560	COG0305	Participates in initiation and elongation during chromosome replication
A3O06_RS04565	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A3O06_RS04590	COG3645	SOS response
A3O06_RS04590	COG3646	Phage regulatory protein
A3O06_RS04595	COG0629	single-stranded DNA binding
A3O06_RS04775	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A3O06_RS04905	COG0739	heme binding
A3O06_RS04975	COG4974	Belongs to the 'phage' integrase family
A3O06_RS05120	COG5651	PPE family
A3O06_RS05125	COG0436	Aminotransferase
A3O06_RS05135	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A3O06_RS05140	COG1960	acyl-CoA dehydrogenase activity
A3O06_RS05145	COG1012	belongs to the aldehyde dehydrogenase family
A3O06_RS05150	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A3O06_RS05165	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS05180	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS05195	COG1024	Enoyl-CoA hydratase
A3O06_RS05240	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A3O06_RS05245	COG0657	acetylesterase activity
A3O06_RS05265	COG0183	Belongs to the thiolase family
A3O06_RS05280	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A3O06_RS05300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A3O06_RS05315	COG1061	Type III restriction enzyme res subunit
A3O06_RS05355	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A3O06_RS05375	COG1278	Cold shock
A3O06_RS05415	COG2814	Major facilitator Superfamily
A3O06_RS05490	COG1764	response to oxidative stress
A3O06_RS05495	COG1846	Transcriptional regulator
A3O06_RS05500	COG1216	Glycosyl transferase, family 2
A3O06_RS05505	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
A3O06_RS05505	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
A3O06_RS05535	COG0259	pyridoxamine-phosphate oxidase activity
A3O06_RS05545	COG0318	PFAM AMP-dependent synthetase and ligase
A3O06_RS05550	COG5651	PPE family
A3O06_RS05555	COG2409	Drug exporters of the RND superfamily
A3O06_RS05580	COG4977	sequence-specific DNA binding
A3O06_RS05605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3O06_RS05615	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A3O06_RS05625	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A3O06_RS05635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3O06_RS05640	COG0545	Peptidyl-prolyl cis-trans isomerase
A3O06_RS05660	COG2072	flavoprotein involved in K transport
A3O06_RS05680	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A3O06_RS05685	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A3O06_RS05725	COG1012	belongs to the aldehyde dehydrogenase family
A3O06_RS05740	COG3022	response to hydroperoxide
A3O06_RS05750	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A3O06_RS05785	COG1309	transcriptional regulator
A3O06_RS05815	COG1393	Belongs to the ArsC family
A3O06_RS05820	COG0583	DNA-binding transcription factor activity
A3O06_RS05860	COG0183	Belongs to the thiolase family
A3O06_RS05905	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A3O06_RS05945	COG0438	transferase activity, transferring glycosyl groups
A3O06_RS05950	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A3O06_RS06000	COG0667	Aldo Keto reductase
A3O06_RS06050	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
A3O06_RS06060	COG1846	Transcriptional regulator
A3O06_RS06105	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
A3O06_RS06115	COG2326	polyphosphate kinase activity
A3O06_RS06130	COG0523	cobalamin synthesis protein
A3O06_RS06135	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A3O06_RS06140	COG0235	Class ii aldolase
A3O06_RS06145	COG1396	sequence-specific DNA binding
A3O06_RS06150	COG0166	Belongs to the GPI family
A3O06_RS06195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3O06_RS06250	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A3O06_RS06280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A3O06_RS06285	COG0521	Mo-molybdopterin cofactor biosynthetic process
A3O06_RS06285	COG0315	cyclic pyranopterin monophosphate synthase activity
A3O06_RS06315	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A3O06_RS06320	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A3O06_RS06365	COG1063	alcohol dehydrogenase
A3O06_RS06380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3O06_RS06415	COG2235	arginine
A3O06_RS06430	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A3O06_RS06445	COG1252	NADH dehydrogenase
A3O06_RS06455	COG0084	hydrolase, TatD family'
A3O06_RS06460	COG3583	domain protein
A3O06_RS06475	COG0515	serine threonine protein kinase
A3O06_RS06475	COG2815	serine threonine protein kinase
A3O06_RS06495	COG1846	Transcriptional regulator
A3O06_RS06495	COG0456	acetyltransferase
A3O06_RS06505	COG0318	PFAM AMP-dependent synthetase and ligase
A3O06_RS06520	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
A3O06_RS06560	COG1309	transcriptional regulator
A3O06_RS06605	COG3956	TIGRFAM MazG family protein
A3O06_RS06620	COG2837	iron assimilation
A3O06_RS06625	COG2822	iron ion transport
A3O06_RS06660	COG0596	Alpha beta hydrolase
A3O06_RS06685	COG0318	PFAM AMP-dependent synthetase and ligase
A3O06_RS06755	COG0427	acetyl-CoA hydrolase
A3O06_RS06815	COG1846	Transcriptional regulator
A3O06_RS06830	COG1024	Enoyl-CoA hydratase
A3O06_RS06855	COG0183	Belongs to the thiolase family
A3O06_RS06860	COG2755	lipolytic protein G-D-S-L family
A3O06_RS06865	COG0657	acetylesterase activity
A3O06_RS06875	COG1714	RDD family
A3O06_RS06890	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A3O06_RS06910	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A3O06_RS06920	COG1331	Highly conserved protein containing a thioredoxin domain
A3O06_RS06925	COG3631	Ketosteroid isomerase-related protein
A3O06_RS06940	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A3O06_RS06945	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS06950	COG2124	cytochrome p450
A3O06_RS06970	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS07010	COG2272	Belongs to the type-B carboxylesterase lipase family
A3O06_RS07020	COG1174	glycine betaine transport
A3O06_RS07025	COG0517	IMP dehydrogenase activity
A3O06_RS07025	COG1125	glycine betaine transport
A3O06_RS07030	COG1174	glycine betaine transport
A3O06_RS07075	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
A3O06_RS07085	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
A3O06_RS07090	COG0726	polysaccharide deacetylase
A3O06_RS07160	COG1570	exodeoxyribonuclease VII activity
A3O06_RS07170	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
A3O06_RS07185	COG1966	Carbon starvation protein
A3O06_RS07210	COG3189	MarR family transcriptional regulator
A3O06_RS07215	COG0012	GTP binding
A3O06_RS07225	COG2132	Multicopper oxidase
A3O06_RS07235	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A3O06_RS07245	COG0488	(ABC) transporter
A3O06_RS07310	COG2409	Drug exporters of the RND superfamily
A3O06_RS07345	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A3O06_RS07365	COG1716	ATPase activity
A3O06_RS07395	COG1051	belongs to the nudix hydrolase family
A3O06_RS07420	COG1217	gtp-binding protein TYPA
A3O06_RS07430	COG2015	COG2015, Alkyl sulfatase and related hydrolases
A3O06_RS07495	COG1902	pentaerythritol trinitrate reductase activity
A3O06_RS07495	COG0446	pyridine nucleotide-disulphide oxidoreductase
A3O06_RS07505	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
A3O06_RS07515	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
A3O06_RS07520	COG1012	belongs to the aldehyde dehydrogenase family
A3O06_RS07525	COG0506	proline dehydrogenase activity
A3O06_RS07530	COG0318	PFAM AMP-dependent synthetase and ligase
A3O06_RS07555	COG2207	Transcriptional regulator
A3O06_RS07570	COG1611	Belongs to the LOG family
A3O06_RS07575	COG1611	Belongs to the LOG family
A3O06_RS07580	COG0318	PFAM AMP-dependent synthetase and ligase
A3O06_RS07590	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A3O06_RS07595	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A3O06_RS07600	COG0463	Glycosyl transferase, family 2
A3O06_RS07615	COG0519	Catalyzes the synthesis of GMP from XMP
A3O06_RS07625	COG0297	glycogen (starch) synthase activity
A3O06_RS07640	COG3559	Exporter of polyketide antibiotics
A3O06_RS07645	COG1131	(ABC) transporter
A3O06_RS07650	COG1309	transcriptional regulator
A3O06_RS07660	COG1595	DNA-templated transcription, initiation
A3O06_RS07665	COG5662	AntiSigma factor
A3O06_RS07670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A3O06_RS07740	COG0598	Magnesium transport protein CorA
A3O06_RS07745	COG2095	MarC family integral membrane protein
A3O06_RS07760	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A3O06_RS07765	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A3O06_RS07785	COG3835	regulator
A3O06_RS07790	COG1073	alpha beta
A3O06_RS07795	COG0508	dehydrogenase complex catalyzes the overall conversion of
A3O06_RS07795	COG0567	Dehydrogenase, E1 component
A3O06_RS07805	COG2814	Major facilitator Superfamily
A3O06_RS07865	COG0277	FAD linked oxidase domain protein
A3O06_RS07870	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS07885	COG0668	transmembrane transport
A3O06_RS07975	COG2814	Major facilitator Superfamily
A3O06_RS08005	COG0019	diaminopimelate decarboxylase activity
A3O06_RS08010	COG0460	homoserine dehydrogenase
A3O06_RS08015	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A3O06_RS08055	COG2890	protein-(glutamine-N5) methyltransferase activity
A3O06_RS08065	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A3O06_RS08075	COG0356	it plays a direct role in the translocation of protons across the membrane
A3O06_RS08080	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
A3O06_RS08105	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
A3O06_RS08165	COG0346	lactoylglutathione lyase activity
A3O06_RS08170	COG0183	Belongs to the thiolase family
A3O06_RS08175	COG2409	Drug exporters of the RND superfamily
A3O06_RS08190	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
A3O06_RS08195	COG0366	Alpha amylase catalytic
A3O06_RS08200	COG0058	SHG alpha-glucan phosphorylase activity
A3O06_RS08215	COG1335	isochorismatase
A3O06_RS08225	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A3O06_RS08240	COG3191	aminopeptidase activity
A3O06_RS08285	COG0604	alcohol dehydrogenase
A3O06_RS08305	COG0318	PFAM AMP-dependent synthetase and ligase
A3O06_RS08320	COG0419	ATPase involved in DNA repair
A3O06_RS08325	COG1024	Enoyl-CoA hydratase
A3O06_RS08335	COG0243	molybdopterin cofactor binding
A3O06_RS08350	COG2188	Transcriptional regulator
A3O06_RS08410	COG0596	Alpha beta hydrolase
A3O06_RS08415	COG3757	hydrolase, family 25
A3O06_RS08430	COG1051	belongs to the nudix hydrolase family
A3O06_RS08450	COG1309	transcriptional regulator
A3O06_RS08465	COG4585	Histidine kinase
A3O06_RS08470	COG2197	response regulator
A3O06_RS08480	COG2239	Acts as a magnesium transporter
A3O06_RS08490	COG0300	oxidoreductase activity
A3O06_RS08500	COG0656	L-ascorbic acid biosynthetic process
A3O06_RS08515	COG1376	ErfK ybiS ycfS ynhG family protein
A3O06_RS08530	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
A3O06_RS08535	COG0433	COG0433 Predicted ATPase
A3O06_RS08550	COG0300	oxidoreductase activity
A3O06_RS08565	COG1301	dicarboxylic acid transport
A3O06_RS08575	COG0531	amino acid
A3O06_RS08595	COG4424	Sulfotransferase
A3O06_RS08600	COG3119	arylsulfatase activity
A3O06_RS08640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3O06_RS08640	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A3O06_RS08690	COG0582	viral genome integration into host DNA
A3O06_RS08720	COG2902	Dehydrogenase
A3O06_RS08725	COG0824	Thioesterase
A3O06_RS08740	COG0366	Alpha amylase catalytic
A3O06_RS08775	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A3O06_RS08795	COG1309	transcriptional regulator
A3O06_RS08830	COG0740	serine-type endopeptidase activity
A3O06_RS08835	COG0740	serine-type endopeptidase activity
A3O06_RS08885	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A3O06_RS08895	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A3O06_RS08895	COG0674	pyruvate-flavodoxin oxidoreductase activity
A3O06_RS08900	COG1013	pyruvate-flavodoxin oxidoreductase activity
A3O06_RS08910	COG1388	LysM domain
A3O06_RS08940	COG0525	valine-tRNA ligase activity
A3O06_RS08945	COG0285	dihydrofolate synthase activity
A3O06_RS08960	COG1530	ribonuclease E activity
A3O06_RS08960	COG1530	ribonuclease E activity
A3O06_RS08980	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
A3O06_RS09000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A3O06_RS09005	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
A3O06_RS09010	COG0542	response to heat
A3O06_RS09020	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
A3O06_RS09030	COG0406	alpha-ribazole phosphatase activity
A3O06_RS09035	COG2755	lipolytic protein G-D-S-L family
A3O06_RS09055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A3O06_RS09090	COG2308	Evidence 4 Homologs of previously reported genes of
A3O06_RS09100	COG1305	Transglutaminase-like
A3O06_RS09130	COG3387	PFAM Glycoside hydrolase 15-related
A3O06_RS09145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A3O06_RS09180	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
A3O06_RS09185	COG4208	sulfate ABC transporter
A3O06_RS09240	COG0484	heat shock protein binding
A3O06_RS09290	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A3O06_RS09340	COG0076	glutamate decarboxylase activity
A3O06_RS09375	COG0318	PFAM AMP-dependent synthetase and ligase
A3O06_RS09380	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A3O06_RS09425	COG0423	glycine-tRNA ligase activity
A3O06_RS09430	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A3O06_RS09435	COG2515	1-aminocyclopropane-1-carboxylate deaminase
A3O06_RS09455	COG0358	DNA primase activity
A3O06_RS09515	COG1175	transmembrane transport
A3O06_RS09530	COG0745	RESPONSE REGULATOR receiver
A3O06_RS09535	COG5002	protein histidine kinase activity
A3O06_RS09595	COG3038	cytochrome b561
A3O06_RS09620	COG0488	(ABC) transporter
A3O06_RS09645	COG1960	acyl-CoA dehydrogenase activity
A3O06_RS09650	COG1335	isochorismatase
A3O06_RS09660	COG0058	SHG alpha-glucan phosphorylase activity
A3O06_RS09700	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A3O06_RS09705	COG1960	acyl-CoA dehydrogenase activity
A3O06_RS09710	COG0183	Belongs to the thiolase family
A3O06_RS09730	COG1228	amidohydrolase
A3O06_RS09760	COG3321	synthase
A3O06_RS09760	COG0604	alcohol dehydrogenase
A3O06_RS09760	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS09780	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A3O06_RS09785	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A3O06_RS09810	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
A3O06_RS09855	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A3O06_RS09900	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
A3O06_RS09905	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
A3O06_RS09965	COG0714	Associated with various cellular activities
A3O06_RS10000	COG0318	PFAM AMP-dependent synthetase and ligase
A3O06_RS10025	COG0174	glutamine synthetase
A3O06_RS10030	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
A3O06_RS10060	COG2205	protein histidine kinase activity
A3O06_RS10090	COG0174	glutamine synthetase
A3O06_RS10100	COG0477	Major facilitator Superfamily
A3O06_RS10110	COG3486	L-lysine 6-monooxygenase (NADPH) activity
A3O06_RS10135	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
A3O06_RS10140	COG0321	lipoyl(octanoyl) transferase activity
A3O06_RS10155	COG1872	DUF167
A3O06_RS10170	COG0404	The glycine cleavage system catalyzes the degradation of glycine
A3O06_RS10175	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A3O06_RS10185	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
A3O06_RS10190	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
A3O06_RS10220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A3O06_RS10265	COG2010	Cytochrome c
A3O06_RS10270	COG1845	cytochrome c oxidase, subunit III
A3O06_RS10310	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A3O06_RS10335	COG0003	Pfam Anion-transporting ATPase
A3O06_RS10345	COG0204	Acyl-transferase
A3O06_RS10350	COG5650	phosphatidylinositol metabolic process
A3O06_RS10360	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
A3O06_RS10385	COG0142	geranyltranstransferase activity
A3O06_RS10425	COG0768	penicillin binding
A3O06_RS10445	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
A3O06_RS10455	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A3O06_RS10470	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A3O06_RS10495	COG0640	Transcriptional regulator
A3O06_RS10545	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A3O06_RS10555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A3O06_RS10565	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS10595	COG2814	Major facilitator Superfamily
A3O06_RS10610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A3O06_RS10640	COG1968	undecaprenyl-diphosphatase activity
A3O06_RS10675	COG1218	3'(2'),5'-bisphosphate nucleotidase
A3O06_RS10685	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS10710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A3O06_RS10720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A3O06_RS10720	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
A3O06_RS10735	COG2860	membrane
A3O06_RS10745	COG1410	methionine synthase
A3O06_RS10745	COG0646	methionine synthase
A3O06_RS10750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A3O06_RS10760	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
A3O06_RS10795	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A3O06_RS10800	COG1034	ATP synthesis coupled electron transport
A3O06_RS10805	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
A3O06_RS10810	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3O06_RS10850	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A3O06_RS10850	COG1017	nitric oxide dioxygenase activity
A3O06_RS10900	COG0513	Belongs to the DEAD box helicase family
A3O06_RS10940	COG0028	Belongs to the TPP enzyme family
A3O06_RS10955	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A3O06_RS10960	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A3O06_RS10965	COG4122	O-methyltransferase activity
A3O06_RS10995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A3O06_RS11000	COG4521	taurine ABC transporter
A3O06_RS11005	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
A3O06_RS11045	COG2378	regulation of single-species biofilm formation
A3O06_RS11050	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A3O06_RS11085	COG0300	oxidoreductase activity
A3O06_RS11140	COG1574	metal-dependent hydrolase with the TIM-barrel fold
A3O06_RS11150	COG0463	Glycosyl transferase, family 2
A3O06_RS11175	COG0604	alcohol dehydrogenase
A3O06_RS11175	COG3321	synthase
A3O06_RS11175	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS11195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A3O06_RS11205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A3O06_RS11210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3O06_RS11230	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
A3O06_RS11240	COG1404	Belongs to the peptidase S8 family
A3O06_RS11255	COG4842	Belongs to the WXG100 family
A3O06_RS11285	COG0464	growth
A3O06_RS11305	COG0583	DNA-binding transcription factor activity
A3O06_RS11335	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A3O06_RS11340	COG1169	isochorismate synthase
A3O06_RS11345	COG0789	Transcriptional regulator
A3O06_RS11350	COG1021	2,3-dihydroxybenzoate-AMP ligase
A3O06_RS11380	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A3O06_RS11385	COG1132	(ABC) transporter
A3O06_RS11390	COG2375	cellular response to nickel ion
A3O06_RS11390	COG1132	(ABC) transporter
A3O06_RS11395	COG0477	Major facilitator Superfamily
A3O06_RS11400	COG5285	phytanoyl-CoA dioxygenase
A3O06_RS11410	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A3O06_RS11415	COG0456	acetyltransferase
A3O06_RS11435	COG2837	iron assimilation
A3O06_RS11445	COG2186	Transcriptional regulator
A3O06_RS11450	COG2807	transmembrane transport
A3O06_RS11460	COG2409	Drug exporters of the RND superfamily
A3O06_RS11465	COG3629	intracellular signal transduction
A3O06_RS11470	COG1012	belongs to the aldehyde dehydrogenase family
A3O06_RS11510	COG0475	glutathione-regulated potassium exporter activity
A3O06_RS11570	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A3O06_RS11570	COG0237	dephospho-CoA kinase activity
A3O06_RS11745	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
A3O06_RS11750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A3O06_RS11750	COG0072	phenylalanine-tRNA ligase activity
A3O06_RS11760	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
A3O06_RS11765	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
A3O06_RS11770	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A3O06_RS11775	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A3O06_RS11780	COG1438	arginine binding
A3O06_RS11785	COG0137	argininosuccinate synthase activity
A3O06_RS11825	COG2835	tetraacyldisaccharide 4'-kinase activity
A3O06_RS11830	COG1309	transcriptional regulator
A3O06_RS11835	COG2094	Belongs to the DNA glycosylase MPG family
A3O06_RS11860	COG0647	UMP catabolic process
A3O06_RS11875	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A3O06_RS11895	COG0504	CTP synthase activity
A3O06_RS11900	COG0494	nUDIX hydrolase
A3O06_RS11915	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
A3O06_RS11920	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
A3O06_RS11935	COG1160	GTP binding
A3O06_RS11945	COG1403	HNH endonuclease
A3O06_RS11985	COG1053	succinate dehydrogenase
A3O06_RS11985	COG3976	FMN-binding domain protein
A3O06_RS12015	COG1960	acyl-CoA dehydrogenase activity
A3O06_RS12070	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A3O06_RS12070	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A3O06_RS12085	COG1253	flavin adenine dinucleotide binding
A3O06_RS12090	COG1253	flavin adenine dinucleotide binding
A3O06_RS12100	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
A3O06_RS12155	COG0832	Belongs to the urease beta subunit family
A3O06_RS12165	COG0830	nickel cation binding
A3O06_RS12180	COG1252	NADH dehydrogenase
A3O06_RS12190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3O06_RS12225	COG0243	molybdopterin cofactor binding
A3O06_RS12235	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A3O06_RS12250	COG1058	Belongs to the CinA family
A3O06_RS12250	COG1546	Belongs to the CinA family
A3O06_RS12260	COG4977	sequence-specific DNA binding
A3O06_RS12265	COG1741	Belongs to the pirin family
A3O06_RS12285	COG1968	undecaprenyl-diphosphatase activity
A3O06_RS12290	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
A3O06_RS12315	COG0277	FAD linked oxidase domain protein
A3O06_RS12325	COG1309	transcriptional regulator
A3O06_RS12340	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
A3O06_RS12345	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A3O06_RS12375	COG4290	ribonuclease
A3O06_RS12405	COG3883	PFAM NLP P60 protein
A3O06_RS12405	COG0791	NLP P60 protein
A3O06_RS12460	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A3O06_RS12465	COG0067	glutamate synthase
A3O06_RS12465	COG0069	glutamate synthase activity
A3O06_RS12465	COG0070	glutamate synthase
A3O06_RS12495	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A3O06_RS12510	COG1960	acyl-CoA dehydrogenase activity
A3O06_RS12525	COG0443	Heat shock 70 kDa protein
A3O06_RS12535	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS12560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A3O06_RS12570	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
A3O06_RS12590	COG2890	protein-(glutamine-N5) methyltransferase activity
A3O06_RS12680	COG2192	nodulation
A3O06_RS12685	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A3O06_RS12690	COG0859	PFAM glycosyl transferase family 9
A3O06_RS12695	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
A3O06_RS12700	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
A3O06_RS12700	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
A3O06_RS12705	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS12715	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A3O06_RS12720	COG1982	Orn Lys Arg decarboxylase major
A3O06_RS12780	COG0028	Belongs to the TPP enzyme family
A3O06_RS12810	COG1309	transcriptional regulator
A3O06_RS12815	COG2957	Belongs to the agmatine deiminase family
A3O06_RS12820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A3O06_RS12830	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A3O06_RS12880	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
A3O06_RS12905	COG0288	reversible hydration of carbon dioxide
A3O06_RS12975	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
A3O06_RS13025	COG0640	Transcriptional regulator
A3O06_RS13035	COG0798	PFAM Bile acid sodium symporter
A3O06_RS13040	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A3O06_RS13070	COG2409	Drug exporters of the RND superfamily
A3O06_RS13080	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A3O06_RS13085	COG4569	acetaldehyde dehydrogenase (acetylating) activity
A3O06_RS13150	COG0668	transmembrane transport
A3O06_RS13165	COG0745	RESPONSE REGULATOR receiver
A3O06_RS13170	COG2205	protein histidine kinase activity
A3O06_RS13190	COG3707	response regulator
A3O06_RS13230	COG3467	pyridoxamine 5'-phosphate
A3O06_RS13255	COG0640	Transcriptional regulator
A3O06_RS13275	COG1309	transcriptional regulator
A3O06_RS13280	COG2072	flavoprotein involved in K transport
A3O06_RS13290	COG0318	PFAM AMP-dependent synthetase and ligase
A3O06_RS13295	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A3O06_RS13300	COG0561	phosphatase activity
A3O06_RS13305	COG0673	inositol 2-dehydrogenase activity
A3O06_RS13310	COG0738	Major facilitator superfamily
A3O06_RS13315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A3O06_RS13395	COG1271	oxidase subunit
A3O06_RS13400	COG1294	oxidase, subunit
A3O06_RS13405	COG4988	ABC transporter
A3O06_RS13410	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
A3O06_RS13435	COG1946	Acyl-CoA thioesterase
A3O06_RS13445	COG2076	Multidrug Resistance protein
A3O06_RS13480	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A3O06_RS13485	COG1846	Transcriptional regulator
A3O06_RS13510	COG2072	flavoprotein involved in K transport
A3O06_RS13515	COG0657	acetylesterase activity
A3O06_RS13570	COG0483	inositol monophosphate 1-phosphatase activity
A3O06_RS13580	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A3O06_RS13585	COG0131	Imidazoleglycerol-phosphate dehydratase
A3O06_RS13590	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A3O06_RS13615	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
A3O06_RS13630	COG1309	transcriptional regulator
A3O06_RS13650	COG0583	DNA-binding transcription factor activity
A3O06_RS13655	COG0579	oxidoreductase
A3O06_RS13695	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
A3O06_RS13695	COG2755	lipolytic protein G-D-S-L family
A3O06_RS13740	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
A3O06_RS13760	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
A3O06_RS13765	COG2814	Major facilitator Superfamily
A3O06_RS13770	COG0583	DNA-binding transcription factor activity
A3O06_RS13820	COG2239	Acts as a magnesium transporter
A3O06_RS13850	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A3O06_RS13860	COG2304	oxidoreductase activity
A3O06_RS13870	COG0714	Associated with various cellular activities
A3O06_RS13880	COG0791	NLP P60 protein
A3O06_RS13880	COG3883	PFAM NLP P60 protein
A3O06_RS13890	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
A3O06_RS13895	COG1309	transcriptional regulator
A3O06_RS13920	COG0488	(ABC) transporter
A3O06_RS13935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A3O06_RS13950	COG0456	acetyltransferase
A3O06_RS13960	COG2151	metal-sulfur cluster biosynthetic enzyme
A3O06_RS13975	COG0396	ATPase activity
A3O06_RS14000	COG1131	(ABC) transporter
A3O06_RS14040	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A3O06_RS14100	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A3O06_RS14160	COG0531	amino acid
A3O06_RS14215	COG2011	ABC-type metal ion transport system permease component
A3O06_RS14220	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A3O06_RS14240	COG0477	Major facilitator Superfamily
A3O06_RS14275	COG0657	acetylesterase activity
A3O06_RS14280	COG1953	Uracil, thiamine, allantoin
A3O06_RS14290	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A3O06_RS14295	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A3O06_RS14305	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
A3O06_RS14315	COG1758	RNA polymerase activity
A3O06_RS14335	COG0284	orotidine-5'-phosphate decarboxylase activity
A3O06_RS14340	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A3O06_RS14345	COG0505	Belongs to the CarA family
A3O06_RS14365	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
A3O06_RS14385	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A3O06_RS14395	COG0006	proline dipeptidase activity
A3O06_RS14410	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
A3O06_RS14415	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
A3O06_RS14430	COG4106	trans-aconitate 2-methyltransferase activity
A3O06_RS14445	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A3O06_RS14460	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A3O06_RS14510	COG0701	Predicted permease
A3O06_RS14535	COG2272	Belongs to the type-B carboxylesterase lipase family
A3O06_RS14575	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A3O06_RS14585	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A3O06_RS14595	COG0747	negative chemotaxis
A3O06_RS14600	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A3O06_RS14615	COG2255	four-way junction helicase activity
A3O06_RS14625	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
A3O06_RS14660	COG1946	Acyl-CoA thioesterase
A3O06_RS14665	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
A3O06_RS14675	COG0438	transferase activity, transferring glycosyl groups
A3O06_RS14715	COG4762	Protein conserved in bacteria
A3O06_RS14745	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A3O06_RS14765	COG4585	Histidine kinase
A3O06_RS14775	COG1305	Transglutaminase-like
A3O06_RS14805	COG2072	flavoprotein involved in K transport
A3O06_RS14825	COG0657	acetylesterase activity
A3O06_RS14830	COG2226	methyltransferase
A3O06_RS14835	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A3O06_RS14845	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A3O06_RS14855	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A3O06_RS14930	COG2072	flavoprotein involved in K transport
A3O06_RS14940	COG2072	flavoprotein involved in K transport
A3O06_RS14950	COG0657	acetylesterase activity
A3O06_RS14955	COG2267	carboxylic ester hydrolase activity
A3O06_RS14970	COG2124	cytochrome p450
A3O06_RS14980	COG0142	geranyltranstransferase activity
A3O06_RS15060	COG0305	Participates in initiation and elongation during chromosome replication
A3O06_RS15105	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
A3O06_RS15110	COG0328	RNA-DNA hybrid ribonuclease activity
A3O06_RS15275	COG1061	Type III restriction enzyme res subunit
A3O06_RS15280	COG1481	regulation of sporulation
A3O06_RS15310	COG1481	regulation of sporulation
A3O06_RS15415	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A3O06_RS15450	COG1674	ftsk spoiiie
A3O06_RS15465	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
A3O06_RS15780	COG1733	regulation of RNA biosynthetic process
A3O06_RS15805	COG0789	Transcriptional regulator
A3O06_RS15810	COG0071	Belongs to the small heat shock protein (HSP20) family
A3O06_RS15830	COG2382	esterase
A3O06_RS15865	COG0038	chloride channel
A3O06_RS16105	COG2161	toxin-antitoxin pair type II binding
A3O06_RS16160	COG2801	Transposase and inactivated derivatives
A3O06_RS16160	COG3415	Transposase
A3O06_RS16200	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A3O06_RS16210	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A3O06_RS16275	COG0328	RNA-DNA hybrid ribonuclease activity
A3O06_RS16285	COG1793	dna ligase
A3O06_RS16285	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
A3O06_RS16445	COG1404	Belongs to the peptidase S8 family
A3O06_RS16530	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
A3O06_RS16620	COG1192	Involved in chromosome partitioning
A3O06_RS16815	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A3O06_RS16830	COG1529	Aldehyde oxidase and xanthine dehydrogenase
A3O06_RS16830	COG2080	2 iron, 2 sulfur cluster binding
A3O06_RS16845	COG0402	S-adenosylhomocysteine deaminase activity
A3O06_RS16865	COG2233	PERMEase
A3O06_RS16885	COG1953	Uracil, thiamine, allantoin
A3O06_RS16895	COG1301	dicarboxylic acid transport
A3O06_RS16905	COG4266	Belongs to the allantoicase family
A3O06_RS16930	COG0501	Belongs to the peptidase M48B family
A3O06_RS16945	COG0477	Major facilitator Superfamily
A3O06_RS17000	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A3O06_RS17010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A3O06_RS17050	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A3O06_RS17070	COG3253	May function as heme-dependent peroxidase
A3O06_RS17075	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
A3O06_RS17080	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
A3O06_RS17090	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
A3O06_RS17105	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
A3O06_RS17110	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A3O06_RS17115	COG0531	amino acid
A3O06_RS17120	COG0569	domain protein
A3O06_RS17150	COG0702	epimerase
A3O06_RS17165	COG0756	dUTP diphosphatase activity
A3O06_RS17210	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A3O06_RS17220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A3O06_RS17260	COG3220	belongs to the UPF0276 family
A3O06_RS17335	COG1388	LysM domain
A3O06_RS17350	COG1960	acyl-CoA dehydrogenase activity
A3O06_RS17360	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A3O06_RS17380	COG1196	nuclear chromosome segregation
A3O06_RS17400	COG1126	abc transporter atp-binding protein
A3O06_RS17405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A3O06_RS17410	COG0765	amino acid transport
A3O06_RS17415	COG0765	amino acid transport
A3O06_RS17465	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
A3O06_RS17470	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
A3O06_RS17485	COG1842	Phage shock protein A
A3O06_RS17490	COG1396	sequence-specific DNA binding
A3O06_RS17500	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS17510	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
A3O06_RS17565	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A3O06_RS17570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A3O06_RS17585	COG3214	Protein conserved in bacteria
A3O06_RS17635	COG0659	secondary active sulfate transmembrane transporter activity
A3O06_RS17645	COG0686	Belongs to the AlaDH PNT family
A3O06_RS17660	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS17710	COG2977	Belongs to the P-Pant transferase superfamily
A3O06_RS17715	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A3O06_RS17735	COG1960	acyl-CoA dehydrogenase activity
A3O06_RS17740	COG1960	acyl-CoA dehydrogenase activity
A3O06_RS17745	COG1024	Enoyl-CoA hydratase
A3O06_RS17770	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A3O06_RS17795	COG1017	nitric oxide dioxygenase activity
A3O06_RS17795	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A3O06_RS17800	COG1959	2 iron, 2 sulfur cluster binding
A3O06_RS17845	COG1648	precorrin-2 dehydrogenase activity
A3O06_RS17845	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A3O06_RS17870	COG0604	alcohol dehydrogenase
A3O06_RS17870	COG3321	synthase
A3O06_RS17870	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS17930	COG0579	oxidoreductase
A3O06_RS17950	COG1492	cobalamin metabolic process
A3O06_RS17960	COG1376	ErfK ybiS ycfS ynhG family protein
A3O06_RS17985	COG0750	zinc metalloprotease
A3O06_RS18010	COG0820	rRNA (adenine-C2-)-methyltransferase activity
A3O06_RS18075	COG0528	UMP kinase activity
A3O06_RS18080	COG3973	AAA domain
A3O06_RS18095	COG2723	6-phospho-beta-galactosidase activity
A3O06_RS18130	COG1309	transcriptional regulator
A3O06_RS18170	COG0583	DNA-binding transcription factor activity
A3O06_RS18260	COG0336	Belongs to the RNA methyltransferase TrmD family
A3O06_RS18300	COG1686	Belongs to the peptidase S11 family
A3O06_RS18320	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
A3O06_RS18340	COG1304	FMN binding
A3O06_RS18390	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
A3O06_RS18395	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
A3O06_RS18415	COG0571	ribonuclease III activity
A3O06_RS18425	COG3599	regulation of cell shape
A3O06_RS18470	COG0742	ribosomal rna small subunit methyltransferase
A3O06_RS18475	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
A3O06_RS18490	COG0657	acetylesterase activity
A3O06_RS18495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3O06_RS18515	COG2124	cytochrome p450
A3O06_RS18530	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A3O06_RS18535	COG1461	Dihydroxyacetone kinase
A3O06_RS18545	COG1024	Enoyl-CoA hydratase
A3O06_RS18570	COG1181	Belongs to the D-alanine--D-alanine ligase family
A3O06_RS18575	COG0626	cystathionine gamma-synthase activity
A3O06_RS18580	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
A3O06_RS18645	COG0179	Fumarylacetoacetate (FAA) hydrolase
A3O06_RS18660	COG2271	Major facilitator Superfamily
A3O06_RS18680	COG1309	transcriptional regulator
A3O06_RS18690	COG2124	cytochrome p450
A3O06_RS18720	COG0440	acetolactate synthase activity
A3O06_RS18735	COG1748	Saccharopine dehydrogenase
A3O06_RS18740	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A3O06_RS18760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A3O06_RS18780	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A3O06_RS18790	COG2272	Belongs to the type-B carboxylesterase lipase family
A3O06_RS18805	COG0745	RESPONSE REGULATOR receiver
A3O06_RS18810	COG2205	protein histidine kinase activity
A3O06_RS18835	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
A3O06_RS18865	COG1024	Enoyl-CoA hydratase
A3O06_RS18870	COG0778	Nitroreductase
A3O06_RS18880	COG2252	PERMEase
A3O06_RS18920	COG2197	response regulator
A3O06_RS18925	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
A3O06_RS18935	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A3O06_RS18960	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
A3O06_RS18975	COG1309	transcriptional regulator
A3O06_RS19000	COG0110	maltose O-acetyltransferase activity
A3O06_RS19005	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A3O06_RS19030	COG1119	ATPase activity
A3O06_RS19040	COG2364	Membrane
A3O06_RS19045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3O06_RS19060	COG4607	ABC-type enterochelin transport system periplasmic component
A3O06_RS19110	COG1064	alcohol dehydrogenase
A3O06_RS19130	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A3O06_RS19135	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS19195	COG0477	Major facilitator Superfamily
A3O06_RS19215	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS19245	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS19270	COG1335	isochorismatase
A3O06_RS19280	COG2855	membrane
A3O06_RS19290	COG0318	PFAM AMP-dependent synthetase and ligase
A3O06_RS19305	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS19310	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A3O06_RS19370	COG2272	Belongs to the type-B carboxylesterase lipase family
A3O06_RS19375	COG2272	Belongs to the type-B carboxylesterase lipase family
A3O06_RS19385	COG0183	Belongs to the thiolase family
A3O06_RS19420	COG1309	transcriptional regulator
A3O06_RS19450	COG0789	Transcriptional regulator
A3O06_RS19460	COG0028	Belongs to the TPP enzyme family
A3O06_RS19555	COG2177	Part of the ABC transporter FtsEX involved in
A3O06_RS19560	COG2884	Cell division ATP-binding protein ftsE
A3O06_RS19570	COG0668	transmembrane transport
A3O06_RS19610	COG0483	inositol monophosphate 1-phosphatase activity
A3O06_RS19615	COG1960	acyl-CoA dehydrogenase activity
A3O06_RS19620	COG1960	acyl-CoA dehydrogenase activity
A3O06_RS19635	COG0318	PFAM AMP-dependent synthetase and ligase
A3O06_RS19645	COG0542	response to heat
A3O06_RS19690	COG3480	Lon protease (S16) C-terminal proteolytic domain
A3O06_RS19695	COG3011	Protein conserved in bacteria
A3O06_RS19710	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A3O06_RS19715	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A3O06_RS19720	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A3O06_RS19755	COG0475	glutathione-regulated potassium exporter activity
A3O06_RS19755	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A3O06_RS19770	COG0596	Alpha beta hydrolase
A3O06_RS19785	COG0745	RESPONSE REGULATOR receiver
A3O06_RS19795	COG2146	nitrite reductase [NAD(P)H] activity
A3O06_RS19795	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A3O06_RS19800	COG2223	nitrite transmembrane transporter activity
A3O06_RS19840	COG0513	Belongs to the DEAD box helicase family
A3O06_RS19855	COG0406	alpha-ribazole phosphatase activity
A3O06_RS19875	COG1597	lipid kinase activity
A3O06_RS19890	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
A3O06_RS19900	COG1595	DNA-templated transcription, initiation
A3O06_RS19910	COG2135	peptidase activity
A3O06_RS19915	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
A3O06_RS19920	COG1162	GTPase activity
A3O06_RS19955	COG1309	transcriptional regulator
A3O06_RS19960	COG0653	protein targeting
A3O06_RS19970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3O06_RS19975	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A3O06_RS19985	COG1309	transcriptional regulator
A3O06_RS20000	COG5401	PFAM Sporulation and spore germination
A3O06_RS20005	COG5002	protein histidine kinase activity
A3O06_RS20015	COG0318	PFAM AMP-dependent synthetase and ligase
A3O06_RS20020	COG1285	pathogenesis
A3O06_RS20060	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A3O06_RS20065	COG0531	amino acid
A3O06_RS20075	COG1482	cell wall glycoprotein biosynthetic process
A3O06_RS20105	COG0391	Required for morphogenesis under gluconeogenic growth conditions
A3O06_RS20110	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
A3O06_RS20110	COG0778	Nitroreductase
A3O06_RS20125	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A3O06_RS20140	COG1316	TRANSCRIPTIONal
A3O06_RS20160	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A3O06_RS20170	COG2175	clavaminate synthase activity
A3O06_RS20195	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
A3O06_RS20195	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
A3O06_RS20205	COG0318	PFAM AMP-dependent synthetase and ligase
A3O06_RS20220	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A3O06_RS20230	COG0424	maF-like protein
A3O06_RS20245	COG2226	methyltransferase
A3O06_RS20255	COG3265	gluconokinase activity
A3O06_RS20260	COG1960	acyl-CoA dehydrogenase activity
A3O06_RS20275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3O06_RS20320	COG1733	regulation of RNA biosynthetic process
A3O06_RS20345	COG4770	biotin carboxylase activity
A3O06_RS20380	COG1012	belongs to the aldehyde dehydrogenase family
A3O06_RS20385	COG1309	transcriptional regulator
A3O06_RS20390	COG1201	RNA secondary structure unwinding
A3O06_RS20405	COG0564	pseudouridine synthase activity
A3O06_RS20425	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
A3O06_RS20425	COG1473	amidohydrolase
A3O06_RS20440	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A3O06_RS20455	COG0791	NLP P60 protein
A3O06_RS20455	COG3883	PFAM NLP P60 protein
A3O06_RS20500	COG2009	succinate dehydrogenase
A3O06_RS20515	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A3O06_RS20520	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A3O06_RS20525	COG1595	DNA-templated transcription, initiation
A3O06_RS20540	COG1686	Belongs to the peptidase S11 family
A3O06_RS20555	COG0708	Exodeoxyribonuclease III
A3O06_RS20615	COG1733	regulation of RNA biosynthetic process
A3O06_RS20620	COG2910	NAD(P)H-binding
A3O06_RS20625	COG0842	Transport permease protein
A3O06_RS20625	COG1131	(ABC) transporter
A3O06_RS20625	COG1716	ATPase activity
A3O06_RS20630	COG1357	PFAM Pentapeptide repeats (8 copies)
A3O06_RS20635	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A3O06_RS20640	COG0587	DNA-directed DNA polymerase activity
A3O06_RS20645	COG1073	alpha beta
A3O06_RS20650	COG1309	transcriptional regulator
A3O06_RS20715	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A3O06_RS20715	COG0519	Catalyzes the synthesis of GMP from XMP
A3O06_RS20725	COG0516	GMP reductase activity
A3O06_RS20785	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
A3O06_RS20800	COG0456	acetyltransferase
A3O06_RS20820	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A3O06_RS20825	COG0076	glutamate decarboxylase activity
A3O06_RS20835	COG2267	carboxylic ester hydrolase activity
A3O06_RS20840	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A3O06_RS20865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3O06_RS20875	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A3O06_RS20880	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A3O06_RS20915	COG1404	Belongs to the peptidase S8 family
A3O06_RS20945	COG2267	carboxylic ester hydrolase activity
A3O06_RS21000	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
A3O06_RS21005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A3O06_RS21015	COG2268	Band 7 protein
A3O06_RS21025	COG1088	dTDP-glucose 4,6-dehydratase activity
A3O06_RS21030	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
A3O06_RS21075	COG0616	signal peptide processing
A3O06_RS21090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3O06_RS21110	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
A3O06_RS21120	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
A3O06_RS21130	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A3O06_RS21145	COG2272	Belongs to the type-B carboxylesterase lipase family
A3O06_RS21170	COG0477	Major facilitator Superfamily
A3O06_RS21185	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
A3O06_RS21225	COG0088	Forms part of the polypeptide exit tunnel
A3O06_RS21230	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
A3O06_RS21235	COG0051	transcription antitermination factor activity, RNA binding
A3O06_RS21270	COG0531	amino acid
A3O06_RS21300	COG0535	radical SAM domain protein
A3O06_RS21325	COG1834	amidinotransferase
A3O06_RS21330	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A3O06_RS21335	COG0531	amino acid
A3O06_RS21380	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
A3O06_RS21385	COG1309	transcriptional regulator
A3O06_RS21410	COG1024	Enoyl-CoA hydratase
A3O06_RS21425	COG1960	acyl-CoA dehydrogenase activity
A3O06_RS21455	COG1113	amino acid transport
A3O06_RS21470	COG0085	RNA polymerase activity
A3O06_RS21475	COG0243	molybdopterin cofactor binding
A3O06_RS21530	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A3O06_RS21545	COG0277	FAD linked oxidase domain protein
A3O06_RS21565	COG4941	Belongs to the sigma-70 factor family
A3O06_RS21600	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A3O06_RS21640	COG0783	Belongs to the Dps family
A3O06_RS21645	COG0693	protein deglycase activity
A3O06_RS21685	COG1404	Belongs to the peptidase S8 family
A3O06_RS21705	COG1280	lysine exporter protein (LysE YggA)
A3O06_RS21775	COG0501	Belongs to the peptidase M48B family
A3O06_RS21780	COG0142	geranyltranstransferase activity
A3O06_RS21785	COG0644	oxidoreductase
A3O06_RS21795	COG0438	transferase activity, transferring glycosyl groups
A3O06_RS21815	COG4948	Mandelate Racemase Muconate Lactonizing
A3O06_RS21835	COG3706	GGDEF domain
A3O06_RS21850	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A3O06_RS21860	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
A3O06_RS21865	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS22065	COG0740	serine-type endopeptidase activity
A3O06_RS22205	COG4974	Belongs to the 'phage' integrase family
A3O06_RS22210	COG4221	oxidoreductase activity
A3O06_RS22250	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A3O06_RS22255	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A3O06_RS22290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A3O06_RS22335	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A3O06_RS22345	COG0785	Cytochrome C biogenesis protein
A3O06_RS22350	COG0386	Belongs to the glutathione peroxidase family
A3O06_RS22355	COG0406	alpha-ribazole phosphatase activity
A3O06_RS22370	COG3590	peptidase
A3O06_RS22420	COG1648	precorrin-2 dehydrogenase activity
A3O06_RS22420	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A3O06_RS22445	COG2030	dehydratase
A3O06_RS22470	COG2070	2-Nitropropane dioxygenase
A3O06_RS22495	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A3O06_RS22550	COG2072	flavoprotein involved in K transport
A3O06_RS22585	COG2072	flavoprotein involved in K transport
A3O06_RS22610	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A3O06_RS22660	COG2072	flavoprotein involved in K transport
A3O06_RS22675	COG2072	flavoprotein involved in K transport
A3O06_RS22680	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS22685	COG0657	acetylesterase activity
A3O06_RS22690	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A3O06_RS22700	COG0745	RESPONSE REGULATOR receiver
A3O06_RS22705	COG5002	protein histidine kinase activity
A3O06_RS22715	COG2072	flavoprotein involved in K transport
A3O06_RS22785	COG2814	Major facilitator Superfamily
A3O06_RS22880	COG2733	membrane
A3O06_RS22890	COG2326	polyphosphate kinase activity
A3O06_RS22895	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A3O06_RS22930	COG2224	Isocitrate lyase
A3O06_RS22975	COG2226	methyltransferase
A3O06_RS23025	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A3O06_RS23060	COG0667	Aldo Keto reductase
A3O06_RS23080	COG4552	Acetyltransferase involved in intracellular survival and related
A3O06_RS23085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3O06_RS23110	COG1505	serine-type exopeptidase activity
A3O06_RS23130	COG2326	polyphosphate kinase activity
A3O06_RS23145	COG2223	nitrite transmembrane transporter activity
A3O06_RS23150	COG0640	Transcriptional regulator
A3O06_RS23175	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
A3O06_RS23195	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A3O06_RS23220	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A3O06_RS23225	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A3O06_RS23230	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS23240	COG1960	acyl-CoA dehydrogenase activity
A3O06_RS23245	COG1960	acyl-CoA dehydrogenase activity
A3O06_RS23250	COG0318	PFAM AMP-dependent synthetase and ligase
A3O06_RS23260	COG2070	2-Nitropropane dioxygenase
A3O06_RS23270	COG1024	Enoyl-CoA hydratase
A3O06_RS23280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3O06_RS23315	COG4638	Rieske (2fe-2S)
A3O06_RS23355	COG0175	sulfate reduction
A3O06_RS23425	COG2814	Major facilitator Superfamily
A3O06_RS23435	COG0351	phosphomethylpyrimidine kinase
A3O06_RS23445	COG1252	NADH dehydrogenase
A3O06_RS23455	COG1309	transcriptional regulator
A3O06_RS23465	COG1012	belongs to the aldehyde dehydrogenase family
A3O06_RS23500	COG0494	nUDIX hydrolase
A3O06_RS23510	COG2234	aminopeptidase activity
A3O06_RS23515	COG2234	aminopeptidase activity
A3O06_RS23525	COG1131	(ABC) transporter
A3O06_RS23530	COG2022	thiamine diphosphate biosynthetic process
A3O06_RS23565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A3O06_RS23570	COG0515	serine threonine protein kinase
A3O06_RS23575	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
A3O06_RS23605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3O06_RS23610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3O06_RS23615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3O06_RS23620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3O06_RS23630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A3O06_RS23635	COG1126	abc transporter atp-binding protein
A3O06_RS23675	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
A3O06_RS23695	COG0415	Belongs to the DNA photolyase family
A3O06_RS23700	COG1090	epimerase
A3O06_RS23710	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A3O06_RS23725	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A3O06_RS23735	COG1595	DNA-templated transcription, initiation
A3O06_RS23760	COG1994	Peptidase M50
A3O06_RS23780	COG0586	Pfam SNARE associated Golgi protein
A3O06_RS23810	COG4221	oxidoreductase activity
A3O06_RS23830	COG0542	response to heat
A3O06_RS23855	COG0789	Transcriptional regulator
A3O06_RS23865	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A3O06_RS23935	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
A3O06_RS23935	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A3O06_RS23955	COG2259	Doxx family
A3O06_RS23975	COG0247	lactate metabolic process
A3O06_RS23975	COG2181	nitrate reductase activity
A3O06_RS23985	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A3O06_RS24025	COG3345	alpha-galactosidase
A3O06_RS24030	COG1262	PFAM Formylglycine-generating sulfatase enzyme
A3O06_RS24035	COG1305	Transglutaminase-like
A3O06_RS24050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A3O06_RS24080	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A3O06_RS24095	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A3O06_RS24110	COG1012	belongs to the aldehyde dehydrogenase family
A3O06_RS24175	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS24180	COG1960	acyl-CoA dehydrogenase activity
A3O06_RS24195	COG3268	Saccharopine dehydrogenase
A3O06_RS24200	COG0318	PFAM AMP-dependent synthetase and ligase
A3O06_RS24205	COG3285	dna ligase
A3O06_RS24205	COG1793	dna ligase
A3O06_RS24215	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A3O06_RS24220	COG0318	PFAM AMP-dependent synthetase and ligase
A3O06_RS24260	COG1309	transcriptional regulator
A3O06_RS24265	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
A3O06_RS24280	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A3O06_RS24285	COG1984	allophanate hydrolase subunit 2
A3O06_RS24350	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
A3O06_RS24355	COG1802	Transcriptional regulator
A3O06_RS24385	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A3O06_RS24395	COG0473	3-isopropylmalate dehydrogenase activity
A3O06_RS24410	COG1053	succinate dehydrogenase
A3O06_RS24430	COG0640	Transcriptional regulator
A3O06_RS24480	COG2318	DinB family
A3O06_RS24485	COG1960	acyl-CoA dehydrogenase activity
A3O06_RS24510	COG0183	Belongs to the thiolase family
A3O06_RS24515	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS24520	COG2030	dehydratase
A3O06_RS24535	COG0659	secondary active sulfate transmembrane transporter activity
A3O06_RS24540	COG1309	transcriptional regulator
A3O06_RS24545	COG0861	Integral membrane protein TerC family
A3O06_RS24570	COG0318	PFAM AMP-dependent synthetase and ligase
A3O06_RS24585	COG1472	Belongs to the glycosyl hydrolase 3 family
A3O06_RS24590	COG4941	Belongs to the sigma-70 factor family
A3O06_RS24605	COG3119	arylsulfatase activity
A3O06_RS24620	COG4981	capsule polysaccharide biosynthetic process
A3O06_RS24655	COG0438	transferase activity, transferring glycosyl groups
A3O06_RS24710	COG2197	response regulator
A3O06_RS24715	COG3850	Histidine kinase
A3O06_RS24735	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
A3O06_RS24765	COG2409	Drug exporters of the RND superfamily
A3O06_RS24830	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A3O06_RS24840	COG2197	response regulator
A3O06_RS24870	COG2353	YceI-like domain
A3O06_RS24890	COG2409	Drug exporters of the RND superfamily
A3O06_RS24905	COG4552	Acetyltransferase involved in intracellular survival and related
A3O06_RS24910	COG1832	CoA-binding protein
A3O06_RS24925	COG3590	peptidase
A3O06_RS24930	COG1376	ErfK ybiS ycfS ynhG family protein
A3O06_RS24935	COG1960	acyl-CoA dehydrogenase activity
A3O06_RS24945	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A3O06_RS24955	COG1937	Protein conserved in bacteria
A3O06_RS24985	COG4122	O-methyltransferase activity
A3O06_RS25000	COG2267	carboxylic ester hydrolase activity
A3O06_RS25030	COG1704	LemA family
A3O06_RS25040	COG0318	PFAM AMP-dependent synthetase and ligase
A3O06_RS25095	COG1024	Enoyl-CoA hydratase
A3O06_RS25100	COG1802	Transcriptional regulator
A3O06_RS25110	COG2267	carboxylic ester hydrolase activity
A3O06_RS25115	COG1309	transcriptional regulator
A3O06_RS25145	COG0435	Glutathione S-transferase
A3O06_RS25185	COG1024	Enoyl-CoA hydratase
A3O06_RS25195	COG2211	Major facilitator Superfamily
A3O06_RS25200	COG2365	Tyrosine phosphatase family
A3O06_RS25250	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A3O06_RS25265	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS25270	COG1012	belongs to the aldehyde dehydrogenase family
A3O06_RS25285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A3O06_RS25290	COG1960	acyl-CoA dehydrogenase activity
A3O06_RS25295	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A3O06_RS25325	COG3800	Transcriptional regulator
A3O06_RS25325	COG1396	sequence-specific DNA binding
A3O06_RS25335	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
A3O06_RS25375	COG0318	PFAM AMP-dependent synthetase and ligase
A3O06_RS25435	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
A3O06_RS25445	COG0129	dihydroxy-acid dehydratase activity
A3O06_RS25470	COG2186	Transcriptional regulator
A3O06_RS25500	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A3O06_RS25505	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A3O06_RS25535	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS25575	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS25595	COG0318	PFAM AMP-dependent synthetase and ligase
A3O06_RS25600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A3O06_RS25605	COG1136	(ABC) transporter
A3O06_RS25615	COG1104	cysteine desulfurase activity
A3O06_RS25675	COG1309	transcriptional regulator
A3O06_RS25680	COG1819	glycosyl
A3O06_RS25725	COG1819	glycosyl
A3O06_RS25825	COG3263	regulation of cellular component size
A3O06_RS25900	COG1595	DNA-templated transcription, initiation
A3O06_RS25910	COG0783	Belongs to the Dps family
A3O06_RS25955	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A3O06_RS25960	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A3O06_RS25975	COG1937	Protein conserved in bacteria
A3O06_RS26000	COG1403	HNH endonuclease
A3O06_RS26070	COG2140	Oxalate decarboxylase
A3O06_RS26095	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
A3O06_RS26115	COG1376	ErfK ybiS ycfS ynhG family protein
A3O06_RS26135	COG2030	dehydratase
A3O06_RS26140	COG0488	(ABC) transporter
A3O06_RS26145	COG3757	hydrolase, family 25
A3O06_RS26205	COG0583	DNA-binding transcription factor activity
A3O06_RS26215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3O06_RS26230	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A3O06_RS26235	COG3757	hydrolase, family 25
A3O06_RS26260	COG2205	protein histidine kinase activity
A3O06_RS26265	COG0745	RESPONSE REGULATOR receiver
A3O06_RS26320	COG1595	DNA-templated transcription, initiation
A3O06_RS26330	COG0667	Aldo Keto reductase
A3O06_RS26405	COG1704	LemA family
A3O06_RS26440	COG0629	single-stranded DNA binding
A3O06_RS26455	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A3O06_RS26485	COG1260	myo-inositol-1-phosphate synthase
A3O06_RS26490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A3O06_RS26495	COG1113	amino acid transport
A3O06_RS26510	COG1309	transcriptional regulator
A3O06_RS26515	COG1028	Short-chain dehydrogenase reductase Sdr
A3O06_RS26530	COG0508	dehydrogenase complex catalyzes the overall conversion of
A3O06_RS26535	COG0022	dehydrogenase e1 component
A3O06_RS26550	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
A3O06_RS26555	COG2311	Membrane
A3O06_RS26620	COG0617	tRNA 3'-terminal CCA addition
A3O06_RS26640	COG1595	DNA-templated transcription, initiation
A3O06_RS26660	COG0860	N-Acetylmuramoyl-L-alanine amidase
A3O06_RS26660	COG3409	Peptidoglycan-binding domain 1 protein
A3O06_RS26670	COG2124	cytochrome p450
A3O06_RS26700	COG1192	Involved in chromosome partitioning
A3O06_RS26705	COG0357	Ribosomal RNA small subunit methyltransferase G
A3O06_RS26715	COG0706	membrane insertase activity