locus-tag	class	description
AOY11_RS00050	COG0583	DNA-binding transcription factor activity
AOY11_RS00065	COG0705	Rhomboid family
AOY11_RS00065	COG0457	Tetratricopeptide repeat
AOY11_RS00100	COG0515	serine threonine protein kinase
AOY11_RS00100	COG2815	serine threonine protein kinase
AOY11_RS00105	COG0515	serine threonine protein kinase
AOY11_RS00110	COG0768	penicillin binding
AOY11_RS00125	COG1716	ATPase activity
AOY11_RS00130	COG1716	ATPase activity
AOY11_RS00145	COG0754	glutathionylspermidine amidase activity
AOY11_RS00155	COG1309	transcriptional regulator
AOY11_RS00175	COG4842	Belongs to the WXG100 family
AOY11_RS00195	COG0590	tRNA wobble adenosine to inosine editing
AOY11_RS00205	COG0583	DNA-binding transcription factor activity
AOY11_RS00210	COG1643	Atp-dependent helicase
AOY11_RS00230	COG4585	Histidine kinase
AOY11_RS00250	COG1960	acyl-CoA dehydrogenase activity
AOY11_RS00295	COG2072	flavoprotein involved in K transport
AOY11_RS00305	COG0346	lactoylglutathione lyase activity
AOY11_RS00310	COG1414	Transcriptional regulator
AOY11_RS00330	COG1053	succinate dehydrogenase
AOY11_RS00360	COG1785	Belongs to the alkaline phosphatase family
AOY11_RS00380	COG0067	glutamate synthase
AOY11_RS00380	COG0070	glutamate synthase
AOY11_RS00380	COG0069	glutamate synthase activity
AOY11_RS00410	COG1796	DNA polymerase
AOY11_RS00410	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AOY11_RS00420	COG2072	flavoprotein involved in K transport
AOY11_RS00430	COG2124	cytochrome p450
AOY11_RS00445	COG1024	Enoyl-CoA hydratase
AOY11_RS00475	COG2372	response to copper ion
AOY11_RS00525	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AOY11_RS00545	COG3447	MASE1 domain protein
AOY11_RS00545	COG5001	Diguanylate cyclase
AOY11_RS00545	COG5002	protein histidine kinase activity
AOY11_RS00555	COG1528	Iron-storage protein
AOY11_RS00560	COG1528	Iron-storage protein
AOY11_RS00565	COG1316	TRANSCRIPTIONal
AOY11_RS00595	COG0406	alpha-ribazole phosphatase activity
AOY11_RS00605	COG0028	Belongs to the TPP enzyme family
AOY11_RS00635	COG2072	flavoprotein involved in K transport
AOY11_RS00645	COG2072	flavoprotein involved in K transport
AOY11_RS00665	COG1285	pathogenesis
AOY11_RS00715	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AOY11_RS00715	COG2146	nitrite reductase [NAD(P)H] activity
AOY11_RS00725	COG4133	protoheme IX ABC transporter activity
AOY11_RS00730	COG2070	2-Nitropropane dioxygenase
AOY11_RS00735	COG1942	4-Oxalocrotonate Tautomerase
AOY11_RS00740	COG0583	DNA-binding transcription factor activity
AOY11_RS00755	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS00770	COG0561	phosphatase activity
AOY11_RS00790	COG1216	Glycosyl transferase, family 2
AOY11_RS00795	COG0671	phosphoesterase, PA-phosphatase related
AOY11_RS00800	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AOY11_RS00805	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AOY11_RS00825	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
AOY11_RS00830	COG0318	PFAM AMP-dependent synthetase and ligase
AOY11_RS00835	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AOY11_RS00835	COG3321	synthase
AOY11_RS00835	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AOY11_RS00840	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AOY11_RS00890	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS00895	COG0277	FAD linked oxidase domain protein
AOY11_RS00910	COG2376	Dihydroxyacetone kinase
AOY11_RS00915	COG2267	carboxylic ester hydrolase activity
AOY11_RS00920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOY11_RS00925	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AOY11_RS00940	COG0671	phosphoesterase, PA-phosphatase related
AOY11_RS00950	COG1216	Glycosyl transferase, family 2
AOY11_RS01025	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AOY11_RS01030	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOY11_RS01100	COG1960	acyl-CoA dehydrogenase activity
AOY11_RS01120	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS01140	COG1174	glycine betaine transport
AOY11_RS01155	COG0287	Prephenate dehydrogenase
AOY11_RS01165	COG0590	tRNA wobble adenosine to inosine editing
AOY11_RS01205	COG0343	queuine tRNA-ribosyltransferase activity
AOY11_RS01215	COG0765	amino acid transport
AOY11_RS01220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOY11_RS01225	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AOY11_RS01230	COG1793	dna ligase
AOY11_RS01260	COG2271	Major facilitator Superfamily
AOY11_RS01265	COG2130	NADP-dependent
AOY11_RS01290	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AOY11_RS01310	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS01350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOY11_RS01375	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AOY11_RS01385	COG0148	phosphopyruvate hydratase activity
AOY11_RS01415	COG0860	N-Acetylmuramoyl-L-alanine amidase
AOY11_RS01440	COG1492	cobalamin metabolic process
AOY11_RS01465	COG1960	acyl-CoA dehydrogenase activity
AOY11_RS01480	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AOY11_RS01555	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AOY11_RS01565	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AOY11_RS01595	COG2070	2-Nitropropane dioxygenase
AOY11_RS01640	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AOY11_RS01645	COG2971	BadF BadG BcrA BcrD
AOY11_RS01650	COG2814	Major facilitator Superfamily
AOY11_RS01670	COG3572	ergothioneine biosynthetic process
AOY11_RS01675	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AOY11_RS01680	COG0121	glutamine amidotransferase
AOY11_RS01685	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AOY11_RS01690	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AOY11_RS01715	COG0183	Belongs to the thiolase family
AOY11_RS01720	COG2030	dehydratase
AOY11_RS01725	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS01730	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AOY11_RS01740	COG1695	Transcriptional regulator
AOY11_RS01750	COG0569	domain protein
AOY11_RS01750	COG0475	glutathione-regulated potassium exporter activity
AOY11_RS01765	COG0714	Associated with various cellular activities
AOY11_RS01810	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AOY11_RS01815	COG1074	ATP-dependent DNA helicase activity
AOY11_RS01820	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AOY11_RS01830	COG2755	lipolytic protein G-D-S-L family
AOY11_RS01860	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AOY11_RS01865	COG1408	metallophosphoesterase
AOY11_RS01900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOY11_RS01940	COG2945	thiolester hydrolase activity
AOY11_RS01940	COG0596	Alpha beta hydrolase
AOY11_RS01955	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AOY11_RS01960	COG0747	negative chemotaxis
AOY11_RS02040	COG0582	viral genome integration into host DNA
AOY11_RS02085	COG2217	Heavy metal translocating P-type atpase
AOY11_RS02095	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AOY11_RS02155	COG2132	Multicopper oxidase
AOY11_RS02190	COG0596	Alpha beta hydrolase
AOY11_RS02325	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AOY11_RS02335	COG0657	acetylesterase activity
AOY11_RS02340	COG1902	pentaerythritol trinitrate reductase activity
AOY11_RS02350	COG1278	Cold shock
AOY11_RS02370	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AOY11_RS02445	COG1215	transferase activity, transferring glycosyl groups
AOY11_RS02480	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AOY11_RS02515	COG2027	D-alanyl-D-alanine carboxypeptidase
AOY11_RS02550	COG1063	alcohol dehydrogenase
AOY11_RS02560	COG2267	carboxylic ester hydrolase activity
AOY11_RS02570	COG1309	transcriptional regulator
AOY11_RS02585	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AOY11_RS02630	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AOY11_RS02640	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AOY11_RS02660	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AOY11_RS02665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOY11_RS02705	COG4977	sequence-specific DNA binding
AOY11_RS02710	COG1194	a g-specific adenine glycosylase
AOY11_RS02720	COG1316	TRANSCRIPTIONal
AOY11_RS02730	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
AOY11_RS02740	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AOY11_RS02760	COG1329	Transcriptional regulator
AOY11_RS02765	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AOY11_RS02775	COG0215	cysteine-tRNA ligase activity
AOY11_RS02785	COG0584	glycerophosphoryl diester phosphodiesterase
AOY11_RS02795	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AOY11_RS02800	COG1120	ATPase activity
AOY11_RS02805	COG0803	Belongs to the bacterial solute-binding protein 9 family
AOY11_RS02815	COG1309	transcriptional regulator
AOY11_RS02820	COG1960	acyl-CoA dehydrogenase activity
AOY11_RS02835	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AOY11_RS02845	COG0346	lactoylglutathione lyase activity
AOY11_RS02885	COG1960	acyl-CoA dehydrogenase activity
AOY11_RS02890	COG1960	acyl-CoA dehydrogenase activity
AOY11_RS02895	COG1960	acyl-CoA dehydrogenase activity
AOY11_RS02900	COG0318	PFAM AMP-dependent synthetase and ligase
AOY11_RS02905	COG1960	acyl-CoA dehydrogenase activity
AOY11_RS02920	COG0183	Belongs to the thiolase family
AOY11_RS02950	COG1024	Enoyl-CoA hydratase
AOY11_RS02955	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS02960	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS02980	COG0183	Belongs to the thiolase family
AOY11_RS02990	COG1960	acyl-CoA dehydrogenase activity
AOY11_RS02995	COG1960	acyl-CoA dehydrogenase activity
AOY11_RS03000	COG2030	dehydratase
AOY11_RS03025	COG2030	dehydratase
AOY11_RS03040	COG3971	2-oxopent-4-enoate hydratase activity
AOY11_RS03090	COG0651	ATP synthesis coupled electron transport
AOY11_RS03100	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AOY11_RS03100	COG2111	Na H antiporter
AOY11_RS03105	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AOY11_RS03125	COG0647	UMP catabolic process
AOY11_RS03150	COG4221	oxidoreductase activity
AOY11_RS03170	COG0459	protein refolding
AOY11_RS03185	COG0714	Associated with various cellular activities
AOY11_RS03365	COG5651	PPE family
AOY11_RS03370	COG0436	Aminotransferase
AOY11_RS03390	COG0531	amino acid
AOY11_RS03395	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AOY11_RS03400	COG1012	belongs to the aldehyde dehydrogenase family
AOY11_RS03410	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AOY11_RS03415	COG2902	Dehydrogenase
AOY11_RS03420	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AOY11_RS03425	COG1960	acyl-CoA dehydrogenase activity
AOY11_RS03430	COG1012	belongs to the aldehyde dehydrogenase family
AOY11_RS03435	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AOY11_RS03445	COG0657	acetylesterase activity
AOY11_RS03460	COG1902	pentaerythritol trinitrate reductase activity
AOY11_RS03475	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS03490	COG1024	Enoyl-CoA hydratase
AOY11_RS03535	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AOY11_RS03540	COG0657	acetylesterase activity
AOY11_RS03560	COG0183	Belongs to the thiolase family
AOY11_RS03575	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AOY11_RS03595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOY11_RS03610	COG1061	Type III restriction enzyme res subunit
AOY11_RS03650	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AOY11_RS03670	COG1278	Cold shock
AOY11_RS03710	COG2814	Major facilitator Superfamily
AOY11_RS03775	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AOY11_RS03780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AOY11_RS03810	COG1012	belongs to the aldehyde dehydrogenase family
AOY11_RS03810	COG2030	dehydratase
AOY11_RS03815	COG1309	transcriptional regulator
AOY11_RS03825	COG1024	Enoyl-CoA hydratase
AOY11_RS03830	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOY11_RS03840	COG3396	Phenylacetate-CoA oxygenase
AOY11_RS03845	COG3460	Phenylacetate-CoA oxygenase
AOY11_RS03850	COG3396	Phenylacetate-CoA oxygenase
AOY11_RS03855	COG2151	metal-sulfur cluster biosynthetic enzyme
AOY11_RS03860	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AOY11_RS03885	COG0179	Fumarylacetoacetate (FAA) hydrolase
AOY11_RS03895	COG2124	cytochrome p450
AOY11_RS03925	COG1764	response to oxidative stress
AOY11_RS03930	COG1846	Transcriptional regulator
AOY11_RS03935	COG1216	Glycosyl transferase, family 2
AOY11_RS03940	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AOY11_RS03970	COG0259	pyridoxamine-phosphate oxidase activity
AOY11_RS03980	COG0318	PFAM AMP-dependent synthetase and ligase
AOY11_RS03985	COG5651	PPE family
AOY11_RS03990	COG2409	Drug exporters of the RND superfamily
AOY11_RS04015	COG4977	sequence-specific DNA binding
AOY11_RS04040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOY11_RS04055	COG0833	amino acid
AOY11_RS04070	COG2186	Transcriptional regulator
AOY11_RS04075	COG0545	Peptidyl-prolyl cis-trans isomerase
AOY11_RS04115	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AOY11_RS04120	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AOY11_RS04165	COG1012	belongs to the aldehyde dehydrogenase family
AOY11_RS04180	COG3022	response to hydroperoxide
AOY11_RS04190	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AOY11_RS04225	COG1309	transcriptional regulator
AOY11_RS04260	COG1393	Belongs to the ArsC family
AOY11_RS04265	COG0583	DNA-binding transcription factor activity
AOY11_RS04305	COG0183	Belongs to the thiolase family
AOY11_RS04350	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AOY11_RS04390	COG0438	transferase activity, transferring glycosyl groups
AOY11_RS04395	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AOY11_RS04410	COG2382	esterase
AOY11_RS04440	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AOY11_RS04450	COG1846	Transcriptional regulator
AOY11_RS04500	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AOY11_RS04510	COG2326	polyphosphate kinase activity
AOY11_RS04525	COG2084	Dehydrogenase
AOY11_RS04540	COG0523	cobalamin synthesis protein
AOY11_RS04545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOY11_RS04550	COG0235	Class ii aldolase
AOY11_RS04555	COG1396	sequence-specific DNA binding
AOY11_RS04560	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AOY11_RS04565	COG0166	Belongs to the GPI family
AOY11_RS04675	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AOY11_RS04705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOY11_RS04710	COG0315	cyclic pyranopterin monophosphate synthase activity
AOY11_RS04710	COG0521	Mo-molybdopterin cofactor biosynthetic process
AOY11_RS04740	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AOY11_RS04745	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AOY11_RS04780	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AOY11_RS04785	COG1104	cysteine desulfurase activity
AOY11_RS04925	COG2235	arginine
AOY11_RS04940	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AOY11_RS04955	COG1252	NADH dehydrogenase
AOY11_RS04965	COG0084	hydrolase, TatD family'
AOY11_RS04970	COG3583	domain protein
AOY11_RS04985	COG0515	serine threonine protein kinase
AOY11_RS04985	COG2815	serine threonine protein kinase
AOY11_RS05010	COG1846	Transcriptional regulator
AOY11_RS05010	COG0456	acetyltransferase
AOY11_RS05015	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AOY11_RS05020	COG0318	PFAM AMP-dependent synthetase and ligase
AOY11_RS05035	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AOY11_RS05070	COG1309	transcriptional regulator
AOY11_RS05115	COG3956	TIGRFAM MazG family protein
AOY11_RS05130	COG2837	iron assimilation
AOY11_RS05170	COG0596	Alpha beta hydrolase
AOY11_RS05195	COG0318	PFAM AMP-dependent synthetase and ligase
AOY11_RS05205	COG0427	acetyl-CoA hydrolase
AOY11_RS05255	COG1846	Transcriptional regulator
AOY11_RS05270	COG1024	Enoyl-CoA hydratase
AOY11_RS05295	COG0183	Belongs to the thiolase family
AOY11_RS05300	COG2755	lipolytic protein G-D-S-L family
AOY11_RS05315	COG1714	RDD family
AOY11_RS05330	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AOY11_RS05350	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AOY11_RS05360	COG1331	Highly conserved protein containing a thioredoxin domain
AOY11_RS05365	COG3631	Ketosteroid isomerase-related protein
AOY11_RS05380	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AOY11_RS05385	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS05390	COG2124	cytochrome p450
AOY11_RS05410	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS05450	COG2272	Belongs to the type-B carboxylesterase lipase family
AOY11_RS05460	COG1174	glycine betaine transport
AOY11_RS05470	COG1174	glycine betaine transport
AOY11_RS05515	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AOY11_RS05525	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AOY11_RS05530	COG0726	polysaccharide deacetylase
AOY11_RS05600	COG1570	exodeoxyribonuclease VII activity
AOY11_RS05610	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AOY11_RS05625	COG1966	Carbon starvation protein
AOY11_RS05650	COG3189	MarR family transcriptional regulator
AOY11_RS05655	COG0012	GTP binding
AOY11_RS05675	COG2132	Multicopper oxidase
AOY11_RS05685	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AOY11_RS05695	COG0488	(ABC) transporter
AOY11_RS05755	COG2409	Drug exporters of the RND superfamily
AOY11_RS05790	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AOY11_RS05810	COG1716	ATPase activity
AOY11_RS05840	COG1051	belongs to the nudix hydrolase family
AOY11_RS05865	COG1217	gtp-binding protein TYPA
AOY11_RS05875	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AOY11_RS05880	COG1609	Transcriptional regulator
AOY11_RS05880	COG2207	Transcriptional regulator
AOY11_RS05940	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOY11_RS05940	COG1902	pentaerythritol trinitrate reductase activity
AOY11_RS05950	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AOY11_RS05960	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AOY11_RS05970	COG0506	proline dehydrogenase activity
AOY11_RS05975	COG0318	PFAM AMP-dependent synthetase and ligase
AOY11_RS06000	COG2207	Transcriptional regulator
AOY11_RS06015	COG1611	Belongs to the LOG family
AOY11_RS06020	COG1611	Belongs to the LOG family
AOY11_RS06025	COG0318	PFAM AMP-dependent synthetase and ligase
AOY11_RS06035	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AOY11_RS06045	COG0463	Glycosyl transferase, family 2
AOY11_RS06060	COG0519	Catalyzes the synthesis of GMP from XMP
AOY11_RS06070	COG0297	glycogen (starch) synthase activity
AOY11_RS06105	COG3559	Exporter of polyketide antibiotics
AOY11_RS06110	COG1131	(ABC) transporter
AOY11_RS06115	COG1309	transcriptional regulator
AOY11_RS06125	COG1595	DNA-templated transcription, initiation
AOY11_RS06130	COG5662	AntiSigma factor
AOY11_RS06135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOY11_RS06205	COG0598	Magnesium transport protein CorA
AOY11_RS06210	COG1309	transcriptional regulator
AOY11_RS06250	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AOY11_RS06270	COG3835	regulator
AOY11_RS06275	COG1073	alpha beta
AOY11_RS06280	COG0567	Dehydrogenase, E1 component
AOY11_RS06280	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOY11_RS06290	COG2814	Major facilitator Superfamily
AOY11_RS06350	COG0277	FAD linked oxidase domain protein
AOY11_RS06355	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS06370	COG0668	transmembrane transport
AOY11_RS06460	COG2814	Major facilitator Superfamily
AOY11_RS06490	COG0019	diaminopimelate decarboxylase activity
AOY11_RS06495	COG0460	homoserine dehydrogenase
AOY11_RS06500	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AOY11_RS06540	COG2890	protein-(glutamine-N5) methyltransferase activity
AOY11_RS06550	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AOY11_RS06560	COG0356	it plays a direct role in the translocation of protons across the membrane
AOY11_RS06565	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AOY11_RS06590	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AOY11_RS06650	COG0346	lactoylglutathione lyase activity
AOY11_RS06655	COG0183	Belongs to the thiolase family
AOY11_RS06660	COG2409	Drug exporters of the RND superfamily
AOY11_RS06675	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AOY11_RS06680	COG0366	Alpha amylase catalytic
AOY11_RS06685	COG0058	SHG alpha-glucan phosphorylase activity
AOY11_RS06700	COG1335	isochorismatase
AOY11_RS06710	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AOY11_RS06725	COG3191	aminopeptidase activity
AOY11_RS06770	COG0604	alcohol dehydrogenase
AOY11_RS06790	COG0318	PFAM AMP-dependent synthetase and ligase
AOY11_RS06810	COG1024	Enoyl-CoA hydratase
AOY11_RS06820	COG0243	molybdopterin cofactor binding
AOY11_RS06835	COG2188	Transcriptional regulator
AOY11_RS06900	COG0596	Alpha beta hydrolase
AOY11_RS06905	COG3757	hydrolase, family 25
AOY11_RS06920	COG1051	belongs to the nudix hydrolase family
AOY11_RS06940	COG1309	transcriptional regulator
AOY11_RS06955	COG4585	Histidine kinase
AOY11_RS06960	COG2197	response regulator
AOY11_RS06970	COG2239	Acts as a magnesium transporter
AOY11_RS06980	COG0300	oxidoreductase activity
AOY11_RS06990	COG0656	L-ascorbic acid biosynthetic process
AOY11_RS07005	COG1376	ErfK ybiS ycfS ynhG family protein
AOY11_RS07020	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AOY11_RS07025	COG0433	COG0433 Predicted ATPase
AOY11_RS07040	COG0300	oxidoreductase activity
AOY11_RS07055	COG1301	dicarboxylic acid transport
AOY11_RS07065	COG0531	amino acid
AOY11_RS07085	COG4424	Sulfotransferase
AOY11_RS07090	COG3119	arylsulfatase activity
AOY11_RS07125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOY11_RS07125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOY11_RS07160	COG2902	Dehydrogenase
AOY11_RS07165	COG0824	Thioesterase
AOY11_RS07215	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AOY11_RS07235	COG1309	transcriptional regulator
AOY11_RS07250	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AOY11_RS07270	COG0740	serine-type endopeptidase activity
AOY11_RS07275	COG0740	serine-type endopeptidase activity
AOY11_RS07325	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AOY11_RS07335	COG0674	pyruvate-flavodoxin oxidoreductase activity
AOY11_RS07335	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AOY11_RS07340	COG1013	pyruvate-flavodoxin oxidoreductase activity
AOY11_RS07350	COG1388	LysM domain
AOY11_RS07385	COG0285	dihydrofolate synthase activity
AOY11_RS07400	COG1530	ribonuclease E activity
AOY11_RS07400	COG1530	ribonuclease E activity
AOY11_RS07430	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AOY11_RS07450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOY11_RS07455	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AOY11_RS07460	COG0542	response to heat
AOY11_RS07470	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AOY11_RS07480	COG0406	alpha-ribazole phosphatase activity
AOY11_RS07485	COG2755	lipolytic protein G-D-S-L family
AOY11_RS07505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOY11_RS07540	COG2308	Evidence 4 Homologs of previously reported genes of
AOY11_RS07550	COG1305	Transglutaminase-like
AOY11_RS07580	COG3387	PFAM Glycoside hydrolase 15-related
AOY11_RS07595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOY11_RS07630	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AOY11_RS07635	COG4208	sulfate ABC transporter
AOY11_RS07695	COG0484	heat shock protein binding
AOY11_RS07745	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AOY11_RS07775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AOY11_RS07790	COG0076	glutamate decarboxylase activity
AOY11_RS07825	COG0318	PFAM AMP-dependent synthetase and ligase
AOY11_RS07830	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AOY11_RS07875	COG0423	glycine-tRNA ligase activity
AOY11_RS07880	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AOY11_RS07885	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AOY11_RS07905	COG0358	DNA primase activity
AOY11_RS07970	COG0745	RESPONSE REGULATOR receiver
AOY11_RS07975	COG5002	protein histidine kinase activity
AOY11_RS08135	COG0488	(ABC) transporter
AOY11_RS08160	COG1960	acyl-CoA dehydrogenase activity
AOY11_RS08165	COG1335	isochorismatase
AOY11_RS08175	COG0058	SHG alpha-glucan phosphorylase activity
AOY11_RS08215	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AOY11_RS08220	COG1960	acyl-CoA dehydrogenase activity
AOY11_RS08225	COG0183	Belongs to the thiolase family
AOY11_RS08245	COG1228	amidohydrolase
AOY11_RS08275	COG0604	alcohol dehydrogenase
AOY11_RS08275	COG3321	synthase
AOY11_RS08275	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS08295	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AOY11_RS08300	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AOY11_RS08325	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AOY11_RS08395	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AOY11_RS08400	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AOY11_RS08460	COG0714	Associated with various cellular activities
AOY11_RS08480	COG0557	exoribonuclease II activity
AOY11_RS08490	COG0318	PFAM AMP-dependent synthetase and ligase
AOY11_RS08515	COG0174	glutamine synthetase
AOY11_RS08520	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AOY11_RS08550	COG2205	protein histidine kinase activity
AOY11_RS08580	COG0174	glutamine synthetase
AOY11_RS08590	COG0477	Major facilitator Superfamily
AOY11_RS08600	COG3486	L-lysine 6-monooxygenase (NADPH) activity
AOY11_RS08620	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AOY11_RS08625	COG0321	lipoyl(octanoyl) transferase activity
AOY11_RS08640	COG1872	DUF167
AOY11_RS08660	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AOY11_RS08670	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AOY11_RS08675	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AOY11_RS08705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOY11_RS08740	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AOY11_RS08755	COG1845	cytochrome c oxidase, subunit III
AOY11_RS08760	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AOY11_RS08795	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AOY11_RS08820	COG0003	Pfam Anion-transporting ATPase
AOY11_RS08830	COG0204	Acyl-transferase
AOY11_RS08835	COG5650	phosphatidylinositol metabolic process
AOY11_RS08845	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AOY11_RS08870	COG0142	geranyltranstransferase activity
AOY11_RS08910	COG0768	penicillin binding
AOY11_RS08930	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AOY11_RS08940	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AOY11_RS08955	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AOY11_RS08980	COG0640	Transcriptional regulator
AOY11_RS09035	COG0154	amidase activity
AOY11_RS09045	COG2957	Belongs to the agmatine deiminase family
AOY11_RS09055	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AOY11_RS09065	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AOY11_RS09075	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS09105	COG2814	Major facilitator Superfamily
AOY11_RS09200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOY11_RS09205	COG2030	dehydratase
AOY11_RS09225	COG1024	Enoyl-CoA hydratase
AOY11_RS09240	COG1309	transcriptional regulator
AOY11_RS09305	COG2072	flavoprotein involved in K transport
AOY11_RS09320	COG0318	PFAM AMP-dependent synthetase and ligase
AOY11_RS09325	COG1960	acyl-CoA dehydrogenase activity
AOY11_RS09345	COG1960	acyl-CoA dehydrogenase activity
AOY11_RS09385	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AOY11_RS09415	COG1968	undecaprenyl-diphosphatase activity
AOY11_RS09450	COG1218	3'(2'),5'-bisphosphate nucleotidase
AOY11_RS09460	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS09485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOY11_RS09495	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AOY11_RS09495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOY11_RS09510	COG2860	membrane
AOY11_RS09520	COG0646	methionine synthase
AOY11_RS09520	COG1410	methionine synthase
AOY11_RS09525	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AOY11_RS09535	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AOY11_RS09575	COG1034	ATP synthesis coupled electron transport
AOY11_RS09580	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AOY11_RS09585	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOY11_RS09665	COG0513	Belongs to the DEAD box helicase family
AOY11_RS09705	COG0028	Belongs to the TPP enzyme family
AOY11_RS09720	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AOY11_RS09725	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AOY11_RS09730	COG4122	O-methyltransferase activity
AOY11_RS09760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOY11_RS09765	COG4521	taurine ABC transporter
AOY11_RS09770	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AOY11_RS09805	COG2378	regulation of single-species biofilm formation
AOY11_RS09810	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AOY11_RS09845	COG0300	oxidoreductase activity
AOY11_RS09900	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AOY11_RS09915	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS09940	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS09940	COG3321	synthase
AOY11_RS09940	COG0604	alcohol dehydrogenase
AOY11_RS09960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOY11_RS09970	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOY11_RS09975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOY11_RS09995	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
AOY11_RS10005	COG1404	Belongs to the peptidase S8 family
AOY11_RS10020	COG4842	Belongs to the WXG100 family
AOY11_RS10050	COG0464	growth
AOY11_RS10070	COG0583	DNA-binding transcription factor activity
AOY11_RS10105	COG1169	isochorismate synthase
AOY11_RS10110	COG0789	Transcriptional regulator
AOY11_RS10115	COG1021	2,3-dihydroxybenzoate-AMP ligase
AOY11_RS10145	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AOY11_RS10155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOY11_RS10170	COG0318	PFAM AMP-dependent synthetase and ligase
AOY11_RS10170	COG0300	oxidoreductase activity
AOY11_RS10170	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS10170	COG3321	synthase
AOY11_RS10170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOY11_RS10185	COG1132	(ABC) transporter
AOY11_RS10190	COG1132	(ABC) transporter
AOY11_RS10190	COG2375	cellular response to nickel ion
AOY11_RS10195	COG0477	Major facilitator Superfamily
AOY11_RS10200	COG5285	phytanoyl-CoA dioxygenase
AOY11_RS10210	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AOY11_RS10215	COG0456	acetyltransferase
AOY11_RS10235	COG2837	iron assimilation
AOY11_RS10245	COG2186	Transcriptional regulator
AOY11_RS10250	COG2807	transmembrane transport
AOY11_RS10260	COG2409	Drug exporters of the RND superfamily
AOY11_RS10265	COG3629	intracellular signal transduction
AOY11_RS10270	COG1012	belongs to the aldehyde dehydrogenase family
AOY11_RS10310	COG0475	glutathione-regulated potassium exporter activity
AOY11_RS10375	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AOY11_RS10375	COG0237	dephospho-CoA kinase activity
AOY11_RS10560	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AOY11_RS10565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOY11_RS10565	COG0072	phenylalanine-tRNA ligase activity
AOY11_RS10575	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AOY11_RS10580	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AOY11_RS10585	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AOY11_RS10590	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AOY11_RS10595	COG1438	arginine binding
AOY11_RS10600	COG0137	argininosuccinate synthase activity
AOY11_RS10640	COG2835	tetraacyldisaccharide 4'-kinase activity
AOY11_RS10645	COG1309	transcriptional regulator
AOY11_RS10650	COG2094	Belongs to the DNA glycosylase MPG family
AOY11_RS10675	COG0647	UMP catabolic process
AOY11_RS10690	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AOY11_RS10710	COG0504	CTP synthase activity
AOY11_RS10715	COG0494	nUDIX hydrolase
AOY11_RS10735	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AOY11_RS10750	COG1160	GTP binding
AOY11_RS10760	COG1403	HNH endonuclease
AOY11_RS10870	COG1960	acyl-CoA dehydrogenase activity
AOY11_RS10925	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AOY11_RS10925	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AOY11_RS10940	COG1253	flavin adenine dinucleotide binding
AOY11_RS10945	COG1253	flavin adenine dinucleotide binding
AOY11_RS10955	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AOY11_RS11010	COG0832	Belongs to the urease beta subunit family
AOY11_RS11020	COG0830	nickel cation binding
AOY11_RS11035	COG1252	NADH dehydrogenase
AOY11_RS11045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOY11_RS11080	COG0243	molybdopterin cofactor binding
AOY11_RS11090	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AOY11_RS11105	COG1546	Belongs to the CinA family
AOY11_RS11105	COG1058	Belongs to the CinA family
AOY11_RS11115	COG4977	sequence-specific DNA binding
AOY11_RS11120	COG1741	Belongs to the pirin family
AOY11_RS11140	COG1968	undecaprenyl-diphosphatase activity
AOY11_RS11145	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AOY11_RS11170	COG0277	FAD linked oxidase domain protein
AOY11_RS11180	COG1309	transcriptional regulator
AOY11_RS11195	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AOY11_RS11200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOY11_RS11205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOY11_RS11230	COG4290	ribonuclease
AOY11_RS11260	COG0791	NLP P60 protein
AOY11_RS11260	COG3883	PFAM NLP P60 protein
AOY11_RS11295	COG0477	Major facilitator Superfamily
AOY11_RS11315	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AOY11_RS11320	COG0070	glutamate synthase
AOY11_RS11320	COG0069	glutamate synthase activity
AOY11_RS11320	COG0067	glutamate synthase
AOY11_RS11350	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AOY11_RS11365	COG1960	acyl-CoA dehydrogenase activity
AOY11_RS11380	COG0443	Heat shock 70 kDa protein
AOY11_RS11385	COG0596	Alpha beta hydrolase
AOY11_RS11405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOY11_RS11415	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AOY11_RS11435	COG2264	protein methyltransferase activity
AOY11_RS11505	COG1982	Orn Lys Arg decarboxylase major
AOY11_RS11560	COG0028	Belongs to the TPP enzyme family
AOY11_RS11570	COG0318	PFAM AMP-dependent synthetase and ligase
AOY11_RS11595	COG2957	Belongs to the agmatine deiminase family
AOY11_RS11600	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AOY11_RS11615	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AOY11_RS11660	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AOY11_RS11675	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AOY11_RS11695	COG0640	Transcriptional regulator
AOY11_RS11705	COG0798	PFAM Bile acid sodium symporter
AOY11_RS11710	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AOY11_RS11715	COG0390	transport system, permease component
AOY11_RS11735	COG0318	PFAM AMP-dependent synthetase and ligase
AOY11_RS11740	COG0179	Fumarylacetoacetate (FAA) hydrolase
AOY11_RS11775	COG2205	protein histidine kinase activity
AOY11_RS11780	COG0745	RESPONSE REGULATOR receiver
AOY11_RS11805	COG4974	Belongs to the 'phage' integrase family
AOY11_RS11810	COG0745	RESPONSE REGULATOR receiver
AOY11_RS11815	COG2205	protein histidine kinase activity
AOY11_RS11830	COG1917	Cupin 2, conserved barrel domain protein
AOY11_RS11835	COG3707	response regulator
AOY11_RS11875	COG3467	pyridoxamine 5'-phosphate
AOY11_RS11880	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
AOY11_RS11900	COG0640	Transcriptional regulator
AOY11_RS11920	COG1309	transcriptional regulator
AOY11_RS11925	COG2072	flavoprotein involved in K transport
AOY11_RS11935	COG0318	PFAM AMP-dependent synthetase and ligase
AOY11_RS11940	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AOY11_RS11945	COG0561	phosphatase activity
AOY11_RS11950	COG0673	inositol 2-dehydrogenase activity
AOY11_RS11955	COG0738	Major facilitator superfamily
AOY11_RS11960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOY11_RS12040	COG1271	oxidase subunit
AOY11_RS12045	COG1294	oxidase, subunit
AOY11_RS12050	COG4988	ABC transporter
AOY11_RS12055	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AOY11_RS12080	COG1946	Acyl-CoA thioesterase
AOY11_RS12125	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AOY11_RS12130	COG1846	Transcriptional regulator
AOY11_RS12160	COG2072	flavoprotein involved in K transport
AOY11_RS12220	COG0483	inositol monophosphate 1-phosphatase activity
AOY11_RS12230	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AOY11_RS12235	COG0131	Imidazoleglycerol-phosphate dehydratase
AOY11_RS12240	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AOY11_RS12265	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AOY11_RS12280	COG1309	transcriptional regulator
AOY11_RS12300	COG0583	DNA-binding transcription factor activity
AOY11_RS12305	COG0579	oxidoreductase
AOY11_RS12345	COG2755	lipolytic protein G-D-S-L family
AOY11_RS12345	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AOY11_RS12400	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AOY11_RS12420	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AOY11_RS12425	COG2814	Major facilitator Superfamily
AOY11_RS12430	COG0583	DNA-binding transcription factor activity
AOY11_RS12480	COG2239	Acts as a magnesium transporter
AOY11_RS12510	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AOY11_RS12520	COG2304	oxidoreductase activity
AOY11_RS12530	COG0714	Associated with various cellular activities
AOY11_RS12540	COG3883	PFAM NLP P60 protein
AOY11_RS12540	COG0791	NLP P60 protein
AOY11_RS12550	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AOY11_RS12555	COG1309	transcriptional regulator
AOY11_RS12580	COG0488	(ABC) transporter
AOY11_RS12595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AOY11_RS12610	COG0456	acetyltransferase
AOY11_RS12620	COG2151	metal-sulfur cluster biosynthetic enzyme
AOY11_RS12635	COG0396	ATPase activity
AOY11_RS12660	COG1131	(ABC) transporter
AOY11_RS12700	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AOY11_RS12720	COG0583	DNA-binding transcription factor activity
AOY11_RS12725	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AOY11_RS12795	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AOY11_RS12855	COG0531	amino acid
AOY11_RS12910	COG2011	ABC-type metal ion transport system permease component
AOY11_RS12915	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AOY11_RS12935	COG0477	Major facilitator Superfamily
AOY11_RS12970	COG0657	acetylesterase activity
AOY11_RS12975	COG1953	Uracil, thiamine, allantoin
AOY11_RS12985	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AOY11_RS12990	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AOY11_RS13000	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AOY11_RS13010	COG1758	RNA polymerase activity
AOY11_RS13030	COG0284	orotidine-5'-phosphate decarboxylase activity
AOY11_RS13040	COG0505	Belongs to the CarA family
AOY11_RS13060	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AOY11_RS13080	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AOY11_RS13090	COG0006	proline dipeptidase activity
AOY11_RS13105	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AOY11_RS13110	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AOY11_RS13125	COG4106	trans-aconitate 2-methyltransferase activity
AOY11_RS13140	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AOY11_RS13155	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AOY11_RS13205	COG0701	Predicted permease
AOY11_RS13230	COG2272	Belongs to the type-B carboxylesterase lipase family
AOY11_RS13270	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AOY11_RS13280	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AOY11_RS13290	COG0747	negative chemotaxis
AOY11_RS13295	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AOY11_RS13310	COG2255	four-way junction helicase activity
AOY11_RS13320	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AOY11_RS13355	COG1946	Acyl-CoA thioesterase
AOY11_RS13360	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AOY11_RS13370	COG0438	transferase activity, transferring glycosyl groups
AOY11_RS13410	COG4762	Protein conserved in bacteria
AOY11_RS13465	COG1309	transcriptional regulator
AOY11_RS13490	COG3878	Protein conserved in bacteria
AOY11_RS13540	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AOY11_RS13590	COG2233	PERMEase
AOY11_RS13610	COG1953	Uracil, thiamine, allantoin
AOY11_RS13620	COG1301	dicarboxylic acid transport
AOY11_RS13630	COG4266	Belongs to the allantoicase family
AOY11_RS13660	COG2267	carboxylic ester hydrolase activity
AOY11_RS13665	COG1960	acyl-CoA dehydrogenase activity
AOY11_RS13670	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS13685	COG0183	Belongs to the thiolase family
AOY11_RS13700	COG0501	Belongs to the peptidase M48B family
AOY11_RS13770	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AOY11_RS13780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AOY11_RS13820	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AOY11_RS13850	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AOY11_RS13855	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AOY11_RS13865	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AOY11_RS13880	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AOY11_RS13885	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AOY11_RS13895	COG0569	domain protein
AOY11_RS13925	COG0702	epimerase
AOY11_RS13940	COG0756	dUTP diphosphatase activity
AOY11_RS13985	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AOY11_RS14035	COG3220	belongs to the UPF0276 family
AOY11_RS14110	COG1388	LysM domain
AOY11_RS14125	COG1960	acyl-CoA dehydrogenase activity
AOY11_RS14135	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AOY11_RS14155	COG1196	nuclear chromosome segregation
AOY11_RS14175	COG1126	abc transporter atp-binding protein
AOY11_RS14180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOY11_RS14185	COG0765	amino acid transport
AOY11_RS14190	COG0765	amino acid transport
AOY11_RS14240	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
AOY11_RS14245	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
AOY11_RS14260	COG1842	Phage shock protein A
AOY11_RS14265	COG1396	sequence-specific DNA binding
AOY11_RS14275	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS14340	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AOY11_RS14345	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOY11_RS14360	COG3214	Protein conserved in bacteria
AOY11_RS14410	COG0659	secondary active sulfate transmembrane transporter activity
AOY11_RS14420	COG0686	Belongs to the AlaDH PNT family
AOY11_RS14435	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS14505	COG2977	Belongs to the P-Pant transferase superfamily
AOY11_RS14510	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AOY11_RS14530	COG1960	acyl-CoA dehydrogenase activity
AOY11_RS14535	COG1960	acyl-CoA dehydrogenase activity
AOY11_RS14540	COG1024	Enoyl-CoA hydratase
AOY11_RS14565	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AOY11_RS14590	COG1017	nitric oxide dioxygenase activity
AOY11_RS14590	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AOY11_RS14595	COG1959	2 iron, 2 sulfur cluster binding
AOY11_RS14640	COG1648	precorrin-2 dehydrogenase activity
AOY11_RS14640	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AOY11_RS14665	COG0604	alcohol dehydrogenase
AOY11_RS14665	COG3321	synthase
AOY11_RS14665	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS14725	COG0579	oxidoreductase
AOY11_RS14745	COG1492	cobalamin metabolic process
AOY11_RS14755	COG1376	ErfK ybiS ycfS ynhG family protein
AOY11_RS14780	COG0750	zinc metalloprotease
AOY11_RS14805	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AOY11_RS14870	COG0528	UMP kinase activity
AOY11_RS14875	COG3973	AAA domain
AOY11_RS14890	COG2723	6-phospho-beta-galactosidase activity
AOY11_RS14925	COG1309	transcriptional regulator
AOY11_RS14965	COG0583	DNA-binding transcription factor activity
AOY11_RS14995	COG0792	nuclease activity
AOY11_RS15055	COG0336	Belongs to the RNA methyltransferase TrmD family
AOY11_RS15095	COG1686	Belongs to the peptidase S11 family
AOY11_RS15115	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AOY11_RS15135	COG1304	FMN binding
AOY11_RS15185	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AOY11_RS15190	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AOY11_RS15210	COG0571	ribonuclease III activity
AOY11_RS15220	COG3599	regulation of cell shape
AOY11_RS15260	COG0742	ribosomal rna small subunit methyltransferase
AOY11_RS15265	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AOY11_RS15280	COG0657	acetylesterase activity
AOY11_RS15285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOY11_RS15305	COG2124	cytochrome p450
AOY11_RS15320	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AOY11_RS15335	COG1024	Enoyl-CoA hydratase
AOY11_RS15360	COG1181	Belongs to the D-alanine--D-alanine ligase family
AOY11_RS15365	COG0626	cystathionine gamma-synthase activity
AOY11_RS15370	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AOY11_RS15380	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AOY11_RS15435	COG0179	Fumarylacetoacetate (FAA) hydrolase
AOY11_RS15450	COG2271	Major facilitator Superfamily
AOY11_RS15485	COG0583	DNA-binding transcription factor activity
AOY11_RS15495	COG0778	Nitroreductase
AOY11_RS15510	COG1309	transcriptional regulator
AOY11_RS15515	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AOY11_RS15520	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AOY11_RS15525	COG2124	cytochrome p450
AOY11_RS15555	COG0440	acetolactate synthase activity
AOY11_RS15570	COG1748	Saccharopine dehydrogenase
AOY11_RS15575	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AOY11_RS15595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOY11_RS15615	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AOY11_RS15625	COG2272	Belongs to the type-B carboxylesterase lipase family
AOY11_RS15640	COG0745	RESPONSE REGULATOR receiver
AOY11_RS15645	COG2205	protein histidine kinase activity
AOY11_RS15670	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AOY11_RS15700	COG1024	Enoyl-CoA hydratase
AOY11_RS15705	COG0778	Nitroreductase
AOY11_RS15715	COG2252	PERMEase
AOY11_RS15755	COG2197	response regulator
AOY11_RS15760	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AOY11_RS15770	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AOY11_RS15795	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AOY11_RS15810	COG1309	transcriptional regulator
AOY11_RS15840	COG0110	maltose O-acetyltransferase activity
AOY11_RS15870	COG1119	ATPase activity
AOY11_RS15880	COG2364	Membrane
AOY11_RS15885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOY11_RS15900	COG4607	ABC-type enterochelin transport system periplasmic component
AOY11_RS15950	COG1064	alcohol dehydrogenase
AOY11_RS15970	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AOY11_RS15975	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS16035	COG0477	Major facilitator Superfamily
AOY11_RS16055	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS16085	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS16110	COG1335	isochorismatase
AOY11_RS16120	COG2855	membrane
AOY11_RS16130	COG0318	PFAM AMP-dependent synthetase and ligase
AOY11_RS16145	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS16155	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS16160	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AOY11_RS16215	COG2272	Belongs to the type-B carboxylesterase lipase family
AOY11_RS16230	COG0183	Belongs to the thiolase family
AOY11_RS16265	COG1309	transcriptional regulator
AOY11_RS16290	COG0789	Transcriptional regulator
AOY11_RS16300	COG0028	Belongs to the TPP enzyme family
AOY11_RS16690	COG0582	viral genome integration into host DNA
AOY11_RS16705	COG2177	Part of the ABC transporter FtsEX involved in
AOY11_RS16710	COG2884	Cell division ATP-binding protein ftsE
AOY11_RS16720	COG0668	transmembrane transport
AOY11_RS16760	COG0483	inositol monophosphate 1-phosphatase activity
AOY11_RS16765	COG1960	acyl-CoA dehydrogenase activity
AOY11_RS16770	COG1960	acyl-CoA dehydrogenase activity
AOY11_RS16785	COG0318	PFAM AMP-dependent synthetase and ligase
AOY11_RS16795	COG0542	response to heat
AOY11_RS16840	COG3480	Lon protease (S16) C-terminal proteolytic domain
AOY11_RS16845	COG3011	Protein conserved in bacteria
AOY11_RS16860	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AOY11_RS16865	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AOY11_RS16875	COG0300	oxidoreductase activity
AOY11_RS16880	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AOY11_RS16915	COG0475	glutathione-regulated potassium exporter activity
AOY11_RS16915	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AOY11_RS16930	COG0596	Alpha beta hydrolase
AOY11_RS16945	COG0745	RESPONSE REGULATOR receiver
AOY11_RS16955	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOY11_RS16960	COG2223	nitrite transmembrane transporter activity
AOY11_RS17000	COG0513	Belongs to the DEAD box helicase family
AOY11_RS17015	COG0406	alpha-ribazole phosphatase activity
AOY11_RS17035	COG1597	lipid kinase activity
AOY11_RS17050	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AOY11_RS17065	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AOY11_RS17070	COG2135	peptidase activity
AOY11_RS17075	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AOY11_RS17115	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AOY11_RS17210	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AOY11_RS17215	COG0604	alcohol dehydrogenase
AOY11_RS17215	COG3321	synthase
AOY11_RS17220	COG3321	synthase
AOY11_RS17220	COG0604	alcohol dehydrogenase
AOY11_RS17225	COG1960	acyl-CoA dehydrogenase activity
AOY11_RS17240	COG0653	protein targeting
AOY11_RS17250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOY11_RS17255	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AOY11_RS17265	COG1309	transcriptional regulator
AOY11_RS17280	COG5401	PFAM Sporulation and spore germination
AOY11_RS17285	COG5002	protein histidine kinase activity
AOY11_RS17295	COG0318	PFAM AMP-dependent synthetase and ligase
AOY11_RS17300	COG1285	pathogenesis
AOY11_RS17330	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AOY11_RS17335	COG0531	amino acid
AOY11_RS17345	COG1482	cell wall glycoprotein biosynthetic process
AOY11_RS17375	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AOY11_RS17380	COG0778	Nitroreductase
AOY11_RS17380	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
AOY11_RS17395	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AOY11_RS17410	COG1316	TRANSCRIPTIONal
AOY11_RS17430	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AOY11_RS17440	COG2175	clavaminate synthase activity
AOY11_RS17465	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AOY11_RS17465	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AOY11_RS17475	COG0318	PFAM AMP-dependent synthetase and ligase
AOY11_RS17490	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AOY11_RS17510	COG3265	gluconokinase activity
AOY11_RS17515	COG1960	acyl-CoA dehydrogenase activity
AOY11_RS17530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOY11_RS17550	COG4770	biotin carboxylase activity
AOY11_RS17560	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AOY11_RS17580	COG1012	belongs to the aldehyde dehydrogenase family
AOY11_RS17585	COG1309	transcriptional regulator
AOY11_RS17605	COG0564	pseudouridine synthase activity
AOY11_RS17625	COG1473	amidohydrolase
AOY11_RS17625	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AOY11_RS17640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AOY11_RS17655	COG0791	NLP P60 protein
AOY11_RS17655	COG3883	PFAM NLP P60 protein
AOY11_RS17700	COG2009	succinate dehydrogenase
AOY11_RS17715	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AOY11_RS17720	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AOY11_RS17725	COG1595	DNA-templated transcription, initiation
AOY11_RS17740	COG1686	Belongs to the peptidase S11 family
AOY11_RS17755	COG0708	Exodeoxyribonuclease III
AOY11_RS17815	COG1733	regulation of RNA biosynthetic process
AOY11_RS17820	COG2910	NAD(P)H-binding
AOY11_RS17825	COG0842	Transport permease protein
AOY11_RS17825	COG1131	(ABC) transporter
AOY11_RS17825	COG1716	ATPase activity
AOY11_RS17830	COG1357	PFAM Pentapeptide repeats (8 copies)
AOY11_RS17845	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AOY11_RS17850	COG0587	DNA-directed DNA polymerase activity
AOY11_RS17855	COG1073	alpha beta
AOY11_RS17860	COG1309	transcriptional regulator
AOY11_RS17925	COG0519	Catalyzes the synthesis of GMP from XMP
AOY11_RS17925	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AOY11_RS17935	COG0516	GMP reductase activity
AOY11_RS17995	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AOY11_RS18010	COG0456	acetyltransferase
AOY11_RS18030	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AOY11_RS18035	COG0076	glutamate decarboxylase activity
AOY11_RS18045	COG2267	carboxylic ester hydrolase activity
AOY11_RS18050	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AOY11_RS18075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOY11_RS18085	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AOY11_RS18090	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AOY11_RS18125	COG1404	Belongs to the peptidase S8 family
AOY11_RS18155	COG2267	carboxylic ester hydrolase activity
AOY11_RS18210	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AOY11_RS18215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOY11_RS18225	COG2268	Band 7 protein
AOY11_RS18235	COG1088	dTDP-glucose 4,6-dehydratase activity
AOY11_RS18240	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AOY11_RS18285	COG0616	signal peptide processing
AOY11_RS18300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOY11_RS18320	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AOY11_RS18330	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AOY11_RS18340	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AOY11_RS18350	COG2272	Belongs to the type-B carboxylesterase lipase family
AOY11_RS18375	COG0477	Major facilitator Superfamily
AOY11_RS18390	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AOY11_RS18430	COG0088	Forms part of the polypeptide exit tunnel
AOY11_RS18435	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AOY11_RS18440	COG0051	transcription antitermination factor activity, RNA binding
AOY11_RS18615	COG2814	Major facilitator Superfamily
AOY11_RS18620	COG0442	prolyl-tRNA aminoacylation
AOY11_RS18640	COG0697	spore germination
AOY11_RS18665	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOY11_RS18720	COG0604	alcohol dehydrogenase
AOY11_RS18725	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AOY11_RS18730	COG0581	inorganic phosphate transmembrane transporter activity
AOY11_RS18750	COG0745	RESPONSE REGULATOR receiver
AOY11_RS18770	COG2897	thiosulfate sulfurtransferase activity
AOY11_RS18820	COG0354	folic acid binding
AOY11_RS18830	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AOY11_RS18860	COG4172	Belongs to the ABC transporter superfamily
AOY11_RS18865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOY11_RS18870	COG0601	transmembrane transport
AOY11_RS18880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AOY11_RS18960	COG1362	aminopeptidase activity
AOY11_RS18965	COG2837	iron assimilation
AOY11_RS18980	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AOY11_RS18990	COG3573	Dehydrogenase
AOY11_RS19000	COG0386	Belongs to the glutathione peroxidase family
AOY11_RS19005	COG0477	Major facilitator Superfamily
AOY11_RS19030	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AOY11_RS19040	COG0436	Aminotransferase
AOY11_RS19070	COG0596	Alpha beta hydrolase
AOY11_RS19080	COG0697	spore germination
AOY11_RS19085	COG0537	adenosine 5'-monophosphoramidase activity
AOY11_RS19090	COG5002	protein histidine kinase activity
AOY11_RS19090	COG5000	phosphorelay sensor kinase activity
AOY11_RS19095	COG0745	RESPONSE REGULATOR receiver
AOY11_RS19205	COG4974	Belongs to the 'phage' integrase family
AOY11_RS19265	COG0535	radical SAM domain protein
AOY11_RS19290	COG1834	amidinotransferase
AOY11_RS19295	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AOY11_RS19300	COG0531	amino acid
AOY11_RS19345	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AOY11_RS19350	COG1309	transcriptional regulator
AOY11_RS19375	COG1024	Enoyl-CoA hydratase
AOY11_RS19390	COG1960	acyl-CoA dehydrogenase activity
AOY11_RS19420	COG1113	amino acid transport
AOY11_RS19435	COG0085	RNA polymerase activity
AOY11_RS19440	COG0243	molybdopterin cofactor binding
AOY11_RS19495	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AOY11_RS19510	COG0277	FAD linked oxidase domain protein
AOY11_RS19530	COG4941	Belongs to the sigma-70 factor family
AOY11_RS19565	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AOY11_RS19605	COG0783	Belongs to the Dps family
AOY11_RS19610	COG0693	protein deglycase activity
AOY11_RS19655	COG1404	Belongs to the peptidase S8 family
AOY11_RS19765	COG1280	lysine exporter protein (LysE YggA)
AOY11_RS19835	COG0501	Belongs to the peptidase M48B family
AOY11_RS19840	COG0142	geranyltranstransferase activity
AOY11_RS19845	COG0644	oxidoreductase
AOY11_RS19855	COG0438	transferase activity, transferring glycosyl groups
AOY11_RS19875	COG4948	Mandelate Racemase Muconate Lactonizing
AOY11_RS19900	COG3706	GGDEF domain
AOY11_RS19915	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AOY11_RS19925	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AOY11_RS19930	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS19935	COG4221	oxidoreductase activity
AOY11_RS19980	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AOY11_RS19985	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AOY11_RS20025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOY11_RS20070	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AOY11_RS20080	COG0785	Cytochrome C biogenesis protein
AOY11_RS20090	COG0406	alpha-ribazole phosphatase activity
AOY11_RS20110	COG3590	peptidase
AOY11_RS20160	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AOY11_RS20160	COG1587	Uroporphyrinogen-III synthase
AOY11_RS20185	COG2030	dehydratase
AOY11_RS20210	COG2070	2-Nitropropane dioxygenase
AOY11_RS20230	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AOY11_RS20235	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AOY11_RS20280	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AOY11_RS20325	COG2072	flavoprotein involved in K transport
AOY11_RS20340	COG1309	transcriptional regulator
AOY11_RS20350	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AOY11_RS20400	COG2072	flavoprotein involved in K transport
AOY11_RS20415	COG2072	flavoprotein involved in K transport
AOY11_RS20420	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS20425	COG0657	acetylesterase activity
AOY11_RS20430	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AOY11_RS20440	COG0745	RESPONSE REGULATOR receiver
AOY11_RS20445	COG5002	protein histidine kinase activity
AOY11_RS20455	COG2072	flavoprotein involved in K transport
AOY11_RS20470	COG0300	oxidoreductase activity
AOY11_RS20525	COG2814	Major facilitator Superfamily
AOY11_RS20620	COG2733	membrane
AOY11_RS20630	COG2326	polyphosphate kinase activity
AOY11_RS20635	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AOY11_RS20670	COG2224	Isocitrate lyase
AOY11_RS20710	COG2226	methyltransferase
AOY11_RS20760	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AOY11_RS20795	COG0667	Aldo Keto reductase
AOY11_RS20815	COG4552	Acetyltransferase involved in intracellular survival and related
AOY11_RS20820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOY11_RS20865	COG1073	alpha beta
AOY11_RS20870	COG2326	polyphosphate kinase activity
AOY11_RS20885	COG2223	nitrite transmembrane transporter activity
AOY11_RS20890	COG0640	Transcriptional regulator
AOY11_RS20920	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AOY11_RS20940	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AOY11_RS20965	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AOY11_RS20970	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AOY11_RS20975	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS20985	COG1960	acyl-CoA dehydrogenase activity
AOY11_RS20995	COG0318	PFAM AMP-dependent synthetase and ligase
AOY11_RS21005	COG2070	2-Nitropropane dioxygenase
AOY11_RS21015	COG1024	Enoyl-CoA hydratase
AOY11_RS21025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOY11_RS21060	COG4638	Rieske (2fe-2S)
AOY11_RS21100	COG0175	sulfate reduction
AOY11_RS21170	COG2814	Major facilitator Superfamily
AOY11_RS21180	COG0351	phosphomethylpyrimidine kinase
AOY11_RS21190	COG1252	NADH dehydrogenase
AOY11_RS21200	COG1309	transcriptional regulator
AOY11_RS21210	COG1012	belongs to the aldehyde dehydrogenase family
AOY11_RS21245	COG0494	nUDIX hydrolase
AOY11_RS21255	COG2234	aminopeptidase activity
AOY11_RS21260	COG2234	aminopeptidase activity
AOY11_RS21270	COG1131	(ABC) transporter
AOY11_RS21275	COG2022	thiamine diphosphate biosynthetic process
AOY11_RS21310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOY11_RS21315	COG0515	serine threonine protein kinase
AOY11_RS21320	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AOY11_RS21350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOY11_RS21355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOY11_RS21360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOY11_RS21365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOY11_RS21375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOY11_RS21380	COG1126	abc transporter atp-binding protein
AOY11_RS21420	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AOY11_RS21450	COG1994	Peptidase M50
AOY11_RS21470	COG0586	Pfam SNARE associated Golgi protein
AOY11_RS21500	COG4221	oxidoreductase activity
AOY11_RS21520	COG0542	response to heat
AOY11_RS21545	COG0789	Transcriptional regulator
AOY11_RS21550	COG0484	heat shock protein binding
AOY11_RS21555	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AOY11_RS21625	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AOY11_RS21625	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AOY11_RS21665	COG2181	nitrate reductase activity
AOY11_RS21665	COG0247	lactate metabolic process
AOY11_RS21675	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AOY11_RS21715	COG3345	alpha-galactosidase
AOY11_RS21720	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AOY11_RS21725	COG1305	Transglutaminase-like
AOY11_RS21740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOY11_RS21810	COG1012	belongs to the aldehyde dehydrogenase family
AOY11_RS21820	COG0454	-acetyltransferase
AOY11_RS21875	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS21880	COG1960	acyl-CoA dehydrogenase activity
AOY11_RS21895	COG3268	Saccharopine dehydrogenase
AOY11_RS21900	COG0318	PFAM AMP-dependent synthetase and ligase
AOY11_RS21905	COG1793	dna ligase
AOY11_RS21905	COG3285	dna ligase
AOY11_RS21910	COG0494	nUDIX hydrolase
AOY11_RS21920	COG2902	Dehydrogenase
AOY11_RS21925	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AOY11_RS21940	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AOY11_RS21960	COG1309	transcriptional regulator
AOY11_RS21970	COG0778	Nitroreductase
AOY11_RS21975	COG0179	Fumarylacetoacetate (FAA) hydrolase
AOY11_RS22000	COG0179	Fumarylacetoacetate (FAA) hydrolase
AOY11_RS22005	COG0318	PFAM AMP-dependent synthetase and ligase
AOY11_RS22010	COG1396	sequence-specific DNA binding
AOY11_RS22030	COG2267	carboxylic ester hydrolase activity
AOY11_RS22035	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AOY11_RS22050	COG4638	Rieske (2fe-2S)
AOY11_RS22060	COG3384	dioxygenase
AOY11_RS22065	COG3971	2-oxopent-4-enoate hydratase activity
AOY11_RS22080	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AOY11_RS22120	COG1309	transcriptional regulator
AOY11_RS22145	COG1309	transcriptional regulator
AOY11_RS22150	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AOY11_RS22235	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AOY11_RS22240	COG1802	Transcriptional regulator
AOY11_RS22270	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AOY11_RS22280	COG0473	3-isopropylmalate dehydrogenase activity
AOY11_RS22295	COG1053	succinate dehydrogenase
AOY11_RS22315	COG0640	Transcriptional regulator
AOY11_RS22365	COG2318	DinB family
AOY11_RS22370	COG1960	acyl-CoA dehydrogenase activity
AOY11_RS22385	COG1660	Displays ATPase and GTPase activities
AOY11_RS22395	COG0183	Belongs to the thiolase family
AOY11_RS22400	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS22405	COG2030	dehydratase
AOY11_RS22420	COG0659	secondary active sulfate transmembrane transporter activity
AOY11_RS22425	COG1309	transcriptional regulator
AOY11_RS22430	COG0861	Integral membrane protein TerC family
AOY11_RS22455	COG0318	PFAM AMP-dependent synthetase and ligase
AOY11_RS22470	COG1472	Belongs to the glycosyl hydrolase 3 family
AOY11_RS22475	COG4941	Belongs to the sigma-70 factor family
AOY11_RS22480	COG3547	Transposase (IS116 IS110 IS902 family)
AOY11_RS22565	COG4981	capsule polysaccharide biosynthetic process
AOY11_RS22600	COG0438	transferase activity, transferring glycosyl groups
AOY11_RS22645	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOY11_RS22690	COG2197	response regulator
AOY11_RS22695	COG3850	Histidine kinase
AOY11_RS22715	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AOY11_RS22745	COG2409	Drug exporters of the RND superfamily
AOY11_RS22790	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AOY11_RS22800	COG2197	response regulator
AOY11_RS22830	COG2353	YceI-like domain
AOY11_RS22850	COG2409	Drug exporters of the RND superfamily
AOY11_RS22865	COG4552	Acetyltransferase involved in intracellular survival and related
AOY11_RS22870	COG1832	CoA-binding protein
AOY11_RS22885	COG3590	peptidase
AOY11_RS22890	COG1376	ErfK ybiS ycfS ynhG family protein
AOY11_RS22905	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AOY11_RS22915	COG1937	Protein conserved in bacteria
AOY11_RS22940	COG1012	belongs to the aldehyde dehydrogenase family
AOY11_RS22945	COG4122	O-methyltransferase activity
AOY11_RS22960	COG2267	carboxylic ester hydrolase activity
AOY11_RS22990	COG1704	LemA family
AOY11_RS23000	COG0318	PFAM AMP-dependent synthetase and ligase
AOY11_RS23055	COG1024	Enoyl-CoA hydratase
AOY11_RS23060	COG1802	Transcriptional regulator
AOY11_RS23070	COG2267	carboxylic ester hydrolase activity
AOY11_RS23075	COG1309	transcriptional regulator
AOY11_RS23105	COG0435	Glutathione S-transferase
AOY11_RS23145	COG1024	Enoyl-CoA hydratase
AOY11_RS23155	COG2211	Major facilitator Superfamily
AOY11_RS23160	COG2365	Tyrosine phosphatase family
AOY11_RS23225	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS23230	COG1012	belongs to the aldehyde dehydrogenase family
AOY11_RS23245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AOY11_RS23250	COG1960	acyl-CoA dehydrogenase activity
AOY11_RS23255	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AOY11_RS23270	COG2226	methyltransferase
AOY11_RS23285	COG1396	sequence-specific DNA binding
AOY11_RS23285	COG3800	Transcriptional regulator
AOY11_RS23295	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AOY11_RS23335	COG0318	PFAM AMP-dependent synthetase and ligase
AOY11_RS23395	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AOY11_RS23425	COG2186	Transcriptional regulator
AOY11_RS23455	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AOY11_RS23460	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AOY11_RS23470	COG0723	plastoquinol--plastocyanin reductase activity
AOY11_RS23490	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS23530	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS23545	COG0318	PFAM AMP-dependent synthetase and ligase
AOY11_RS23550	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AOY11_RS23555	COG1136	(ABC) transporter
AOY11_RS23565	COG1104	cysteine desulfurase activity
AOY11_RS23625	COG1309	transcriptional regulator
AOY11_RS23635	COG1819	glycosyl
AOY11_RS23660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOY11_RS23690	COG1819	glycosyl
AOY11_RS23800	COG3263	regulation of cellular component size
AOY11_RS23880	COG1595	DNA-templated transcription, initiation
AOY11_RS23890	COG0783	Belongs to the Dps family
AOY11_RS23930	COG1252	NADH dehydrogenase
AOY11_RS23950	COG1937	Protein conserved in bacteria
AOY11_RS23975	COG1403	HNH endonuclease
AOY11_RS24050	COG2140	Oxalate decarboxylase
AOY11_RS24075	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AOY11_RS24095	COG1376	ErfK ybiS ycfS ynhG family protein
AOY11_RS24115	COG2030	dehydratase
AOY11_RS24125	COG3757	hydrolase, family 25
AOY11_RS24190	COG0583	DNA-binding transcription factor activity
AOY11_RS24200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOY11_RS24215	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AOY11_RS24220	COG3757	hydrolase, family 25
AOY11_RS24425	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AOY11_RS24455	COG0745	RESPONSE REGULATOR receiver
AOY11_RS24460	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AOY11_RS24520	COG0640	Transcriptional regulator
AOY11_RS24525	COG0640	Transcriptional regulator
AOY11_RS24530	COG0798	PFAM Bile acid sodium symporter
AOY11_RS24535	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AOY11_RS24540	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOY11_RS24550	COG0717	Belongs to the dCTP deaminase family
AOY11_RS24580	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AOY11_RS24605	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AOY11_RS24615	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AOY11_RS24650	COG0454	-acetyltransferase
AOY11_RS24695	COG0629	single-stranded DNA binding
AOY11_RS24710	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AOY11_RS24740	COG1260	myo-inositol-1-phosphate synthase
AOY11_RS24750	COG1113	amino acid transport
AOY11_RS24765	COG1309	transcriptional regulator
AOY11_RS24770	COG1028	Short-chain dehydrogenase reductase Sdr
AOY11_RS24785	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOY11_RS24790	COG0022	dehydrogenase e1 component
AOY11_RS24805	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AOY11_RS24810	COG2311	Membrane
AOY11_RS24875	COG0617	tRNA 3'-terminal CCA addition
AOY11_RS24895	COG1595	DNA-templated transcription, initiation
AOY11_RS24915	COG3409	Peptidoglycan-binding domain 1 protein
AOY11_RS24915	COG0860	N-Acetylmuramoyl-L-alanine amidase
AOY11_RS24925	COG2124	cytochrome p450
AOY11_RS24935	COG1309	transcriptional regulator
AOY11_RS24955	COG1192	Involved in chromosome partitioning
AOY11_RS24960	COG0357	Ribosomal RNA small subunit methyltransferase G
AOY11_RS24970	COG0706	membrane insertase activity
AOY11_RS25000	COG0592	DNA-directed DNA polymerase activity
AOY11_RS25005	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AOY11_RS25010	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AOY11_RS25015	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
AOY11_RS25020	COG0187	DNA topoisomerase II activity
AOY11_RS25085	COG0582	viral genome integration into host DNA
AOY11_RS25120	COG1674	ftsk spoiiie
AOY11_RS25125	COG1674	ftsk spoiiie
AOY11_RS25255	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AOY11_RS25395	COG0740	serine-type endopeptidase activity
AOY11_RS25525	COG4584	PFAM Integrase catalytic
AOY11_RS25540	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate